# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Aldedh PF00171.17 CCF47883.1 - 2.9e-14 52.2 0.0 3.3e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RVT_2 PF07727.9 CCF47884.1 - 1.6e-42 145.2 0.3 2.2e-42 144.7 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ERCC4 PF02732.10 CCF47884.1 - 0.028 14.1 0.1 0.067 12.9 0.0 1.6 2 0 0 2 2 2 0 ERCC4 domain RVT_1 PF00078.22 CCF47885.1 - 1.8e-06 27.4 0.0 3.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF47886.1 - 3.4e-20 72.3 0.0 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Abhydrolase_6 PF12697.2 CCF47893.1 - 1.2e-29 103.8 1.3 3.2e-29 102.4 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF47893.1 - 2e-18 66.8 0.0 3.1e-15 56.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF47893.1 - 9.1e-14 51.4 0.0 1.3e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 CCF47893.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CCF47893.1 - 5.5e-06 26.1 0.0 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 CCF47893.1 - 0.0003 20.5 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 CCF47893.1 - 0.00033 19.9 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 CCF47893.1 - 0.00062 19.4 0.0 0.0016 18.0 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.9 CCF47893.1 - 0.0054 15.2 0.0 0.01 14.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 CCF47893.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF915 PF06028.6 CCF47893.1 - 0.015 14.3 0.0 0.093 11.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 CCF47893.1 - 0.019 14.8 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 CCF47893.1 - 0.031 13.7 0.0 5.9 6.2 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 CCF47893.1 - 0.033 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 CCF47893.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RVT_2 PF07727.9 CCF47894.1 - 0.003 16.5 0.1 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UPF0061 PF02696.9 CCF47894.1 - 0.069 11.4 0.1 0.078 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family DUF221 PF02714.10 CCF47895.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF221 HA2 PF04408.18 CCF47897.1 - 4e-19 68.5 1.8 4.6e-19 68.3 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF47897.1 - 1.3e-12 47.3 0.1 3.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCF47897.1 - 4e-11 42.7 0.1 1.1e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCF47897.1 - 3.4e-10 39.6 0.0 6.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF47897.1 - 2.9e-08 33.9 0.0 8.7e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCF47897.1 - 0.0018 18.6 8.0 0.095 13.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CCF47897.1 - 0.022 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CCF47897.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CCF47897.1 - 0.073 13.3 0.5 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 ABC transporter RuvA_C PF07499.8 CCF47897.1 - 0.22 11.6 5.1 0.27 11.4 0.1 3.3 3 0 0 3 3 3 0 RuvA, C-terminal domain P16-Arc PF04699.9 CCF47898.1 - 1.8e-49 167.6 0.0 2e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) AviRa PF11599.3 CCF47898.1 - 0.038 13.0 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF1296 PF06972.6 CCF47898.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) RVT_2 PF07727.9 CCF47899.1 - 0.059 12.3 0.1 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NST1 PF13945.1 CCF47900.1 - 6.3e-51 173.1 2.5 6.3e-51 173.1 1.7 7.6 4 3 2 7 7 7 3 Salt tolerance down-regulator SET PF00856.23 CCF47901.1 - 3.8e-13 50.0 0.0 4.3e-10 40.1 0.0 2.6 3 0 0 3 3 3 2 SET domain Urb2 PF10441.4 CCF47901.1 - 0.029 13.9 0.8 0.029 13.9 0.6 2.2 2 0 0 2 2 2 0 Urb2/Npa2 family RRM_1 PF00076.17 CCF47902.1 - 1.2e-13 50.4 0.0 1.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF47902.1 - 1.5e-09 37.6 0.0 2.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF47902.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCF47902.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3827 PF12877.2 CCF47902.1 - 1.4 6.9 7.0 1.8 6.5 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) rve PF00665.21 CCF47903.1 - 1.2e-11 44.7 0.7 3.5e-08 33.5 0.1 2.5 1 1 1 2 2 2 2 Integrase core domain gag_pre-integrs PF13976.1 CCF47903.1 - 2.3e-05 23.9 0.0 5.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_Tnp_1 PF01609.16 CCF47903.1 - 0.072 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain RVT_2 PF07727.9 CCF47904.1 - 2.3e-49 167.5 0.0 3.9e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF47905.1 - 9.9e-22 77.3 0.0 1.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adap_comp_sub PF00928.16 CCF47906.1 - 4.9e-22 78.2 0.0 7.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCF47906.1 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain COX5A PF02284.11 CCF47907.1 - 2e-40 137.0 0.2 2.4e-40 136.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Cas_Cas02710 PF09670.5 CCF47907.1 - 0.065 11.8 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) PspA_IM30 PF04012.7 CCF47907.1 - 0.1 11.9 0.3 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 PspA/IM30 family RRM_6 PF14259.1 CCF47908.1 - 4.3e-11 42.6 0.0 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCF47908.1 - 1.9e-08 33.9 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CCF47908.1 - 6.5e-08 32.2 0.4 3.8e-07 29.8 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF47908.1 - 1.9e-07 30.6 0.5 0.019 14.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCF47908.1 - 2.6e-06 26.9 3.8 4.6e-06 26.1 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 CCF47908.1 - 1.2e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_3 PF08777.6 CCF47908.1 - 0.00039 20.2 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 RNA binding motif Seryl_tRNA_N PF02403.17 CCF47908.1 - 0.61 10.1 14.0 0.041 13.9 5.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_60s PF00428.14 CCF47908.1 - 0.86 10.0 34.0 0.49 10.8 2.9 4.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein Ribosomal_L18ae PF01775.12 CCF47909.1 - 2e-59 198.9 2.1 2.4e-59 198.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain UQ_con PF00179.21 CCF47910.1 - 6.2e-34 116.4 0.0 8e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WD40 PF00400.27 CCF47912.1 - 1.6e-10 40.4 10.4 0.00026 20.7 0.3 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat VHS PF00790.14 CCF47913.1 - 2.6e-16 59.5 0.1 4.5e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 VHS domain MarR_2 PF12802.2 CCF47913.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 MarR family Ras PF00071.17 CCF47914.1 - 3.2e-58 195.7 0.0 3.7e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF47914.1 - 2.1e-19 70.1 0.0 3.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF47914.1 - 2.5e-12 46.3 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF47914.1 - 1.5e-06 27.8 0.0 2.8e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF47914.1 - 5.2e-06 25.7 0.0 6.5e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF47914.1 - 2e-05 24.5 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCF47914.1 - 0.017 15.2 0.1 0.83 9.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 CCF47914.1 - 0.028 14.4 0.8 0.13 12.2 0.6 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCF47914.1 - 0.042 13.0 0.1 0.12 11.6 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 CCF47914.1 - 0.11 11.7 0.1 0.33 10.1 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Imm15 PF15590.1 CCF47915.1 - 0.31 10.1 1.0 0.58 9.2 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 15 RHS PF03527.9 CCF47917.1 - 0.026 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 RHS protein RVT_2 PF07727.9 CCF47918.1 - 4e-33 114.4 0.0 6e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_11 PF13414.1 CCF47919.1 - 5.4e-25 86.8 32.5 6.9e-11 41.6 0.4 11.6 9 3 5 14 14 13 8 TPR repeat TPR_17 PF13431.1 CCF47919.1 - 4.8e-20 70.0 8.2 0.00094 19.2 0.0 11.4 14 0 0 14 14 11 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCF47919.1 - 3e-18 64.5 21.2 0.00067 19.1 0.1 11.0 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCF47919.1 - 1.5e-17 63.7 52.4 0.00015 22.2 0.6 14.2 14 2 3 17 17 14 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCF47919.1 - 2.2e-17 61.4 42.7 0.0019 17.9 0.3 15.8 18 0 0 18 18 18 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF47919.1 - 1.6e-15 55.6 16.7 0.077 12.8 0.0 11.5 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF47919.1 - 2.7e-15 56.0 34.6 2.9e-05 23.9 0.0 10.8 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF47919.1 - 3.8e-13 48.7 51.5 0.0028 18.1 0.2 15.3 11 4 6 17 17 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCF47919.1 - 2.5e-09 37.3 32.8 0.5 10.7 2.8 10.0 10 1 0 11 11 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCF47919.1 - 1.2e-08 34.1 12.1 0.52 10.2 0.0 8.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF47919.1 - 6.6e-05 22.9 0.0 6.6e-05 22.9 0.0 7.1 8 1 0 9 9 8 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 CCF47919.1 - 0.00074 18.3 0.2 0.047 12.4 0.0 3.0 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 CCF47919.1 - 0.0008 19.2 12.5 0.51 10.2 0.3 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCF47919.1 - 0.005 17.2 28.7 0.71 10.4 0.2 11.1 15 0 0 15 15 10 1 Tetratricopeptide repeat Apolipoprotein PF01442.13 CCF47920.1 - 2.9e-05 23.6 5.1 9.3e-05 22.0 3.3 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 CCF47920.1 - 3e-05 23.8 7.5 0.0063 16.3 0.9 2.6 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.7 CCF47920.1 - 0.048 12.1 1.2 0.077 11.4 0.9 1.3 1 0 0 1 1 1 0 Dor1-like family Gp58 PF07902.6 CCF47920.1 - 0.051 11.7 0.6 0.075 11.2 0.4 1.1 1 0 0 1 1 1 0 gp58-like protein zf-AD PF07776.10 CCF47920.1 - 0.055 13.4 3.0 0.088 12.8 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF1876 PF08962.6 CCF47920.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) GvpL_GvpF PF06386.6 CCF47920.1 - 0.18 11.3 1.8 0.31 10.6 1.3 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF ApoLp-III PF07464.6 CCF47920.1 - 0.18 11.8 7.7 2.4 8.1 0.7 2.6 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DHC PF09626.5 CCF47920.1 - 0.25 11.9 3.3 15 6.2 0.1 2.7 2 0 0 2 2 2 0 Dihaem cytochrome c IncA PF04156.9 CCF47920.1 - 1.1 8.7 6.1 3.4 7.2 4.2 1.8 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 CCF47920.1 - 4 7.4 9.2 0.39 10.6 2.1 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 CCF47920.1 - 4.1 7.2 6.5 0.99 9.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SUR7 PF06687.7 CCF47921.1 - 4.1e-27 95.1 8.0 5.5e-27 94.7 5.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family MMPL PF03176.10 CCF47921.1 - 0.21 10.2 3.5 0.37 9.4 2.5 1.3 1 0 0 1 1 1 0 MMPL family HpaP PF09483.5 CCF47921.1 - 1.8 8.4 7.1 0.18 11.7 0.5 2.2 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Claudin_2 PF13903.1 CCF47921.1 - 4.3 6.9 15.2 2.6 7.7 8.9 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ANTH PF07651.11 CCF47922.1 - 1.1e-74 250.6 0.3 1.1e-74 250.6 0.2 2.3 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 CCF47922.1 - 1.6e-62 209.9 9.2 1.6e-62 209.9 6.4 4.1 4 1 1 5 5 5 2 I/LWEQ domain ENTH PF01417.15 CCF47922.1 - 3.1e-09 36.7 0.8 1.7e-08 34.3 0.1 2.7 2 0 0 2 2 2 1 ENTH domain ATP-synt_ab PF00006.20 CCF47922.1 - 0.064 12.7 0.8 0.15 11.5 0.5 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PCI PF01399.22 CCF47923.1 - 3.5e-18 65.8 0.0 3.6e-17 62.5 0.0 2.5 2 1 0 2 2 2 1 PCI domain DUF1510 PF07423.6 CCF47923.1 - 0.0014 18.0 7.7 0.0027 17.1 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CCF47923.1 - 0.026 14.5 12.8 0.11 12.4 8.9 2.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 CCF47923.1 - 0.054 11.2 7.8 0.074 10.7 5.4 1.3 1 0 0 1 1 1 0 Ycf1 Cnd1_N PF12922.2 CCF47923.1 - 0.55 9.8 7.6 8 6.0 0.0 3.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term RNase_H2-Ydr279 PF09468.5 CCF47923.1 - 9.8 5.2 16.4 0.64 9.1 6.3 2.1 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Pkinase PF00069.20 CCF47924.1 - 3.2e-39 134.6 0.0 4.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF47924.1 - 6.4e-16 58.2 0.0 8.5e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF47924.1 - 1e-05 25.4 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CCF47924.1 - 0.02 13.7 0.1 0.032 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UBN2 PF14223.1 CCF47925.1 - 0.0029 17.3 0.2 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2183 PF09949.4 CCF47926.1 - 1e-24 86.3 0.0 3e-24 84.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF1489 PF07370.6 CCF47926.1 - 0.056 12.9 0.5 4.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1489) RVT_1 PF00078.22 CCF47928.1 - 1.3e-08 34.4 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CCF47928.1 - 0.0032 17.1 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like SNARE PF05739.14 CCF47929.1 - 1e-16 60.3 2.4 1.3e-16 60.0 0.7 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCF47929.1 - 6.6e-15 55.1 0.5 6.6e-15 55.1 0.3 2.5 2 1 0 2 2 2 1 Syntaxin DUF1664 PF07889.7 CCF47929.1 - 0.012 15.4 2.2 0.077 12.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CCF47929.1 - 0.042 13.7 1.2 0.14 12.1 0.2 2.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin-18_N PF10496.4 CCF47929.1 - 0.055 13.3 1.1 0.37 10.6 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin-6_N PF09177.6 CCF47929.1 - 0.11 12.9 3.7 1 9.8 0.2 2.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal MCPsignal PF00015.16 CCF47929.1 - 0.15 11.6 4.5 0.52 9.8 0.5 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.4 CCF47929.1 - 0.3 11.2 3.9 3.3 7.8 0.4 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 CCF47929.1 - 0.8 10.1 4.9 1.8 9.0 0.4 2.7 2 1 0 2 2 2 0 SlyX DUF148 PF02520.12 CCF47929.1 - 4.3 7.1 7.8 0.67 9.7 1.3 2.5 2 1 1 3 3 3 0 Domain of unknown function DUF148 DNA_pol_B_thumb PF14791.1 CCF47930.1 - 2e-20 72.2 0.0 4.5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CCF47930.1 - 5.8e-10 39.2 0.0 2.4e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 CCF47930.1 - 8.5e-09 35.4 0.0 3.7e-08 33.4 0.0 2.1 2 1 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CCF47930.1 - 0.00011 21.6 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DASH_Dad2 PF08654.5 CCF47930.1 - 0.062 13.2 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 SR-25 PF10500.4 CCF47930.1 - 3.2 7.1 11.4 5.7 6.3 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Abhydrolase_5 PF12695.2 CCF47931.1 - 0.0001 22.0 0.4 0.00024 20.8 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF47931.1 - 0.0019 18.1 0.6 0.008 16.0 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCF47931.1 - 0.032 13.6 0.0 0.71 9.2 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Rifin_STEVOR PF02009.11 CCF47931.1 - 0.19 11.3 0.2 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Syndecan PF01034.15 CCF47931.1 - 2.8 7.6 4.9 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Syndecan domain ABC_tran PF00005.22 CCF47932.1 - 9.2e-36 123.1 0.0 1.8e-34 118.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CCF47932.1 - 6.7e-32 110.9 7.3 8.5e-32 110.6 5.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CCF47932.1 - 2e-07 31.3 0.0 0.012 15.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 CCF47932.1 - 6.6e-06 25.5 0.1 0.00079 18.7 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 CCF47932.1 - 0.0008 19.6 0.0 0.0086 16.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF47932.1 - 0.0023 17.9 0.1 0.031 14.2 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 CCF47932.1 - 0.0075 15.7 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 CCF47932.1 - 0.015 15.1 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCF47932.1 - 0.018 15.2 0.1 0.13 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCF47932.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCF47932.1 - 0.082 13.7 0.0 0.18 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCF47932.1 - 0.094 12.4 0.0 0.55 9.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CCF47932.1 - 0.11 12.4 1.4 0.42 10.5 0.1 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CCF47932.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Archease PF01951.11 CCF47933.1 - 0.0019 18.1 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 2 Archease protein family (MTH1598/TM1083) Aminotran_1_2 PF00155.16 CCF47934.1 - 3.9e-92 309.0 0.0 4.5e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Retrotrans_gag PF03732.12 CCF47936.1 - 0.0069 16.4 0.6 0.011 15.7 0.1 1.7 1 1 0 1 1 1 1 Retrotransposon gag protein Rsa3 PF14615.1 CCF47937.1 - 0.00016 20.8 0.0 0.00016 20.8 0.0 2.2 3 1 0 3 3 3 1 Ribosome-assembly protein 3 DUF3350 PF11830.3 CCF47937.1 - 0.052 13.5 0.1 0.052 13.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) DUF605 PF04652.11 CCF47937.1 - 2.9 7.1 28.0 4 6.7 19.4 1.2 1 0 0 1 1 1 0 Vta1 like RVT_2 PF07727.9 CCF47938.1 - 1.6e-16 60.0 0.0 2.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF47939.1 - 8.5e-10 38.7 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF47939.1 - 7.4e-06 25.5 3.0 7.4e-06 25.5 2.1 2.2 3 0 0 3 3 3 1 GAG-pre-integrase domain RVT_2 PF07727.9 CCF47940.1 - 9e-52 175.4 0.1 1e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF47940.1 - 0.0036 16.6 0.4 0.011 15.0 0.3 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Hid1 PF12722.2 CCF47943.1 - 0.083 10.5 0.0 0.088 10.4 0.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_A12 PF04651.8 CCF47944.1 - 2.2e-05 24.6 0.0 2.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A12 protein RVT_2 PF07727.9 CCF47948.1 - 3.8e-30 104.6 0.2 5.9e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1817 PF08847.6 CCF47948.1 - 0.026 14.0 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1817) UBN2 PF14223.1 CCF47949.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CCF47949.1 - 0.0029 17.1 0.3 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 CCF47949.1 - 0.0038 17.0 1.6 0.01 15.6 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 CCF47949.1 - 0.0052 16.3 1.1 0.018 14.6 0.0 2.3 2 1 1 3 3 3 1 gag-polypeptide of LTR copia-type PAAR_motif PF05488.8 CCF47949.1 - 0.027 14.4 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 PAAR motif zf-CCHC_3 PF13917.1 CCF47949.1 - 0.063 13.0 2.3 0.16 11.7 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle TryThrA_C PF12319.3 CCF47950.1 - 0.046 12.8 3.4 0.068 12.3 2.3 1.2 1 0 0 1 1 1 0 Tryptophan-Threonine-rich plasmodium antigen C terminal GATA PF00320.22 CCF47951.1 - 1.9e-15 55.9 2.7 3.1e-15 55.1 1.9 1.4 1 0 0 1 1 1 1 GATA zinc finger Pdase_C33_assoc PF14756.1 CCF47951.1 - 0.016 14.8 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase_C33-associated domain PIH1 PF08190.7 CCF47951.1 - 0.74 9.1 7.5 2 7.7 5.2 1.7 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Macoilin PF09726.4 CCF47951.1 - 1 7.5 11.4 1.6 6.9 7.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 CCF47951.1 - 9.6 4.3 9.7 16 3.6 6.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M43 PF05572.8 CCF47952.1 - 4.8e-17 61.9 0.2 8.2e-17 61.2 0.1 1.5 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 CCF47952.1 - 7.5e-07 29.2 2.5 7.5e-07 29.2 1.7 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CCF47952.1 - 7.4e-05 23.2 1.9 7.4e-05 23.2 0.4 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CCF47952.1 - 0.00017 21.6 3.7 0.00017 21.6 2.5 1.8 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CCF47952.1 - 0.052 13.0 3.2 0.16 11.4 2.2 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CCF47952.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Matrixin zf-CHCC PF10276.4 CCF47954.1 - 1e-16 60.4 0.6 1.5e-16 59.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 CCF47954.1 - 0.0081 15.8 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb OTU PF02338.14 CCF47958.1 - 5.2e-15 56.1 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease LRV PF01816.12 CCF47958.1 - 0.16 12.2 0.3 0.36 11.1 0.2 1.6 1 0 0 1 1 1 0 Leucine rich repeat variant F_actin_cap_B PF01115.12 CCF47959.1 - 3.5e-103 344.0 0.0 4e-103 343.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit LptE PF04390.7 CCF47959.1 - 0.041 13.6 0.5 0.47 10.1 0.0 2.1 1 1 1 2 2 2 0 Lipopolysaccharide-assembly gag_pre-integrs PF13976.1 CCF47962.1 - 6.9e-08 32.0 0.1 1.2e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain NinF PF05810.7 CCF47962.1 - 0.032 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 NinF protein TgMIC1 PF11476.3 CCF47962.1 - 0.054 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF3584 PF12128.3 CCF47963.1 - 0.029 11.7 39.0 0.046 11.0 27.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 CCF47963.1 - 0.24 11.1 50.4 0.015 15.0 13.7 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 CCF47963.1 - 2.5 8.0 21.1 2.9 7.8 0.2 5.6 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF4588 PF15251.1 CCF47964.1 - 0.16 11.9 1.4 0.21 11.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF834 PF05754.9 CCF47965.1 - 0.017 14.9 1.6 0.017 14.9 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF834) Ras PF00071.17 CCF47966.1 - 1.2e-56 190.5 0.0 1.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF47966.1 - 8.8e-18 64.9 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF47966.1 - 2.5e-12 46.3 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF47966.1 - 1.6e-06 28.0 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCF47966.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF47966.1 - 3.7e-05 23.2 0.0 0.00071 19.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCF47966.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCF47966.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CCF47966.1 - 0.0032 16.9 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCF47966.1 - 0.0038 16.2 0.1 0.053 12.5 0.0 2.2 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 CCF47966.1 - 0.0052 16.7 0.0 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CCF47966.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCF47966.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 CCF47966.1 - 0.0086 15.5 0.0 0.029 13.8 0.0 1.7 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CCF47966.1 - 0.0096 15.4 0.3 0.6 9.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CCF47966.1 - 0.011 15.5 0.0 0.06 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CCF47966.1 - 0.013 14.9 0.1 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 CCF47966.1 - 0.02 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 CCF47966.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 CCF47966.1 - 0.035 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCF47966.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 CCF47966.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B RVT_2 PF07727.9 CCF47967.1 - 9.1e-32 109.9 0.0 1e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3408 PF11888.3 CCF47967.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) rve PF00665.21 CCF47969.1 - 6.3e-08 32.7 0.1 9.8e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain 2-oxoacid_dh PF00198.18 CCF47970.1 - 3.8e-78 261.9 0.2 5e-78 261.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCF47970.1 - 1.3e-20 72.8 1.2 2.5e-20 71.8 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 CCF47970.1 - 4.2e-17 61.4 0.2 1.2e-16 60.0 0.2 1.9 1 0 0 1 1 1 1 e3 binding domain Granin PF01271.12 CCF47970.1 - 0.0069 15.1 4.7 0.0096 14.6 3.2 1.1 1 0 0 1 1 1 1 Granin (chromogranin or secretogranin) DUF755 PF05501.6 CCF47970.1 - 0.0074 16.3 6.4 0.0074 16.3 4.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF755) Macoilin PF09726.4 CCF47970.1 - 0.6 8.3 4.5 0.8 7.9 3.1 1.3 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CCF47970.1 - 1.4 8.3 21.1 0.012 15.1 7.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 CCF47970.1 - 9 4.2 8.9 14 3.6 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 CCF47971.1 - 9.4e-15 54.1 26.6 2.2e-14 52.9 18.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CCF47971.1 - 8.1e-05 21.1 14.0 0.00013 20.5 9.0 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 CCF47971.1 - 0.051 12.1 14.6 0.0055 15.3 5.9 1.8 1 1 1 2 2 2 0 Sugar (and other) transporter RVT_1 PF00078.22 CCF47973.1 - 2.2e-25 89.2 0.0 4.5e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 CCF47973.1 - 0.0012 18.4 0.8 0.0023 17.5 0.5 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Thoc2 PF11732.3 CCF47973.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Usp PF00582.21 CCF47976.1 - 5.7e-22 78.4 0.7 5.7e-22 78.4 0.5 2.2 2 0 0 2 2 2 1 Universal stress protein family Vps51 PF08700.6 CCF47977.1 - 6.1e-18 64.4 0.1 1.1e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 Vps51/Vps67 FlgN PF05130.7 CCF47977.1 - 0.013 15.7 0.5 0.073 13.3 0.1 2.0 2 0 0 2 2 2 0 FlgN protein Dor1 PF04124.7 CCF47977.1 - 0.018 13.5 0.2 0.022 13.2 0.2 1.1 1 0 0 1 1 1 0 Dor1-like family COG5 PF10392.4 CCF47977.1 - 0.04 13.8 2.2 0.068 13.1 1.5 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Pribosyltran PF00156.22 CCF47978.1 - 5.5e-09 35.8 0.0 9.4e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2OG-FeII_Oxy_2 PF13532.1 CCF47979.1 - 3.5e-11 43.2 0.0 5.4e-11 42.6 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCF47979.1 - 0.00036 20.7 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 CCF47980.1 - 7.6e-19 68.2 4.0 2e-18 66.8 0.2 2.3 1 1 2 3 3 3 1 short chain dehydrogenase KR PF08659.5 CCF47980.1 - 2e-07 30.8 1.3 4.1e-07 29.8 0.2 1.9 2 1 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 CCF47980.1 - 1.5e-06 27.3 0.0 2.8e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCF47980.1 - 1.2e-05 24.3 0.4 1.4e-05 24.1 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 CCF47980.1 - 1.4e-05 25.0 0.1 4.4e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCF47980.1 - 7.7e-05 22.2 0.1 0.00029 20.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCF47980.1 - 0.00011 21.0 0.3 0.00016 20.5 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCF47980.1 - 0.031 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF47980.1 - 0.096 12.6 0.8 1 9.3 0.6 2.2 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 CCF47981.1 - 1.7e-70 237.8 12.8 2e-70 237.6 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF47981.1 - 4e-16 58.6 16.7 4e-16 58.6 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCF47981.1 - 1.3e-05 23.7 22.6 0.0018 16.7 0.8 4.2 3 2 2 5 5 5 2 MFS/sugar transport protein OTU PF02338.14 CCF47982.1 - 5.6e-15 56.0 0.1 1.4e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease AT_hook PF02178.14 CCF47982.1 - 0.19 11.4 5.7 0.57 10.0 4.0 1.9 1 0 0 1 1 1 0 AT hook motif DUF1199 PF06712.6 CCF47982.1 - 0.44 10.3 3.9 2 8.3 2.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) ArfGap PF01412.13 CCF47987.1 - 1.9e-35 121.1 0.2 4e-35 120.1 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 CCF47987.1 - 9.5e-12 45.0 0.0 4.7e-11 42.8 0.0 2.3 3 0 0 3 3 3 1 PH domain PH_9 PF15410.1 CCF47987.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain tRNA-synt_1c PF00749.16 CCF47988.1 - 3.1e-81 272.4 0.0 4.6e-81 271.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Rft-1 PF04506.8 CCF47989.1 - 1.6e-70 238.0 0.0 2.4e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Rft protein Tho2 PF11262.3 CCF47990.1 - 1.5e-73 247.4 0.0 2.6e-73 246.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CCF47990.1 - 3.7e-28 97.1 0.2 1.2e-27 95.4 0.1 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit RhoGEF PF00621.15 CCF47991.1 - 9e-33 113.6 0.0 2.3e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain Chibby PF14645.1 CCF47991.1 - 0.13 12.1 7.1 0.15 11.9 0.2 3.1 1 1 2 3 3 3 0 Chibby family RRM_1 PF00076.17 CCF47992.1 - 8.6e-37 124.6 1.4 1.8e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF47992.1 - 2e-27 94.9 0.1 3.7e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF47992.1 - 1.1e-14 53.9 0.0 2.1e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF47992.1 - 0.0065 16.2 2.5 0.11 12.2 0.0 2.9 2 1 0 2 2 2 1 Limkain b1 RRM_3 PF08777.6 CCF47992.1 - 0.086 12.7 9.5 0.1 12.4 0.3 3.0 2 1 0 3 3 3 0 RNA binding motif DUF221 PF02714.10 CCF47992.1 - 0.16 10.7 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF221 Menin PF05053.8 CCF47992.1 - 1.3 7.0 9.9 1.8 6.6 6.9 1.2 1 0 0 1 1 1 0 Menin OB_RNB PF08206.6 CCF47992.1 - 5.2 6.6 7.0 1.4 8.5 0.0 3.3 4 0 0 4 4 4 0 Ribonuclease B OB domain Hid1 PF12722.2 CCF47992.1 - 5.8 4.4 7.7 8.3 3.9 5.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LtrA PF06772.6 CCF47993.1 - 7.5e-17 61.2 18.1 8.1e-11 41.4 5.1 3.2 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) EnY2 PF10163.4 CCF47994.1 - 3.3e-19 68.5 0.0 4.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 Actino_peptide PF14408.1 CCF47994.1 - 3.3 7.7 7.8 6.4 6.7 5.4 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes zf-CCHC PF00098.18 CCF47995.1 - 9.8e-06 25.2 1.3 2.1e-05 24.1 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF1771 PF08590.5 CCF47998.1 - 3.4e-15 55.8 4.8 3.4e-15 55.8 3.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CCF47998.1 - 2.4e-07 30.8 0.1 6.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 CCF47998.1 - 6.1e-05 22.5 11.6 0.0047 16.5 1.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 CCF47998.1 - 0.016 15.3 1.4 0.032 14.3 0.0 2.1 2 0 0 2 2 2 0 HBS1 N-terminus Tombus_P19 PF03220.8 CCF48004.1 - 0.02 14.2 0.1 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Tombusvirus P19 core protein ERF PF04404.7 CCF48004.1 - 0.025 14.1 1.2 0.03 13.8 0.1 1.6 1 1 0 1 1 1 0 ERF superfamily Herpes_PAP PF03325.8 CCF48004.1 - 0.035 13.6 4.3 0.043 13.3 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein RVT_1 PF00078.22 CCF48006.1 - 2.9e-07 30.0 0.0 5.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CCF48006.1 - 0.011 15.4 0.1 0.055 13.1 0.0 2.1 3 0 0 3 3 3 0 Phage integrase family zf-C2H2 PF00096.21 CCF48007.1 - 3.2e-06 27.1 12.3 0.00029 20.9 2.2 4.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF48007.1 - 0.00085 19.5 12.9 0.0036 17.5 0.9 4.6 4 0 0 4 4 4 1 Zinc-finger double domain TRAP_alpha PF03896.11 CCF48007.1 - 0.087 11.8 2.7 0.18 10.8 1.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-C2H2_jaz PF12171.3 CCF48007.1 - 0.89 9.7 4.9 1.9 8.7 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCF48007.1 - 4.1 7.4 10.9 1.1 9.2 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCF48007.1 - 4.9 6.9 7.3 4.9 6.9 0.4 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 CCF48007.1 - 8 7.0 19.8 0.3 11.4 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger NIF3 PF01784.13 CCF48008.1 - 7.7e-62 209.0 0.0 9.2e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.7 CCF48009.1 - 1.9e-39 135.5 0.3 2.9e-39 134.9 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCF48009.1 - 2.3e-23 81.9 0.2 4.7e-23 80.9 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RNA_pol_A_bac PF01000.21 CCF48010.1 - 4.4e-28 97.6 0.0 7.9e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCF48010.1 - 4.3e-16 57.7 0.0 6.1e-16 57.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_C65 PF10275.4 CCF48011.1 - 3.2e-71 239.5 0.0 3.8e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CCF48011.1 - 0.0011 19.6 0.0 0.006 17.1 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease TetR_C PF02909.12 CCF48011.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain Fungal_trans PF04082.13 CCF48012.1 - 7.7e-17 61.0 0.2 1.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF48012.1 - 3.5e-05 23.6 11.0 5.5e-05 22.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_dim PF02852.17 CCF48013.1 - 6.2e-42 142.0 1.5 1.1e-41 141.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCF48013.1 - 3.4e-39 134.8 14.6 8.9e-30 104.0 3.3 3.4 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF48013.1 - 4.9e-20 71.7 11.4 1.8e-17 63.4 1.8 3.6 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCF48013.1 - 1.8e-11 43.8 8.8 2.2e-11 43.4 0.3 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCF48013.1 - 3.3e-09 37.1 6.7 2.2e-05 24.6 1.5 3.2 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCF48013.1 - 6.4e-09 35.1 12.1 4.6e-07 29.0 4.5 3.0 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCF48013.1 - 1.6e-07 30.5 3.7 1.6e-07 30.5 2.6 4.0 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.12 CCF48013.1 - 3.1e-07 29.7 3.8 0.00017 20.7 0.1 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 CCF48013.1 - 3.6e-07 28.9 14.4 0.00024 19.7 1.1 4.1 4 0 0 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.1 CCF48013.1 - 6.9e-07 29.1 4.8 0.00056 19.8 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCF48013.1 - 3.9e-06 26.1 10.5 0.023 13.7 0.5 3.5 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.19 CCF48013.1 - 2.1e-05 23.5 15.1 0.002 17.0 0.3 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCF48013.1 - 5.4e-05 22.2 1.7 0.18 10.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CCF48013.1 - 0.00016 21.2 5.1 0.042 13.4 0.1 2.8 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Mqo PF06039.10 CCF48013.1 - 0.028 12.6 3.5 0.04 12.1 0.3 2.1 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 CCF48013.1 - 0.064 12.1 3.6 0.27 10.0 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCF48013.1 - 1.6 8.3 9.9 0.095 12.3 0.8 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3506 PF12014.3 CCF48014.1 - 1e-09 38.3 0.0 4.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 CCF48014.1 - 2.8e-09 36.5 0.1 6.2e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF48014.1 - 2.3e-05 23.8 0.0 6.6e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain Aa_trans PF01490.13 CCF48015.1 - 5.1e-22 77.9 35.5 6.6e-22 77.5 24.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2368 PF10166.4 CCF48015.1 - 0.048 13.2 0.1 0.048 13.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Myb_DNA-bind_4 PF13837.1 CCF48016.1 - 0.061 13.4 2.2 0.11 12.6 0.5 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain 60KD_IMP PF02096.15 CCF48017.1 - 5.9e-39 133.7 0.9 9.2e-39 133.1 0.6 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Membr_traf_MHD PF10540.4 CCF48018.1 - 1.9e-18 66.6 0.2 2.9e-17 62.7 0.1 2.7 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CCF48018.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain zf-NPL4 PF05020.10 CCF48018.1 - 0.018 14.6 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 NPL4 family, putative zinc binding region Nucleos_tra2_C PF07662.8 CCF48018.1 - 0.041 13.3 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus Phage_Gp19 PF09355.5 CCF48019.1 - 0.095 12.5 1.1 2.8 7.7 0.0 2.8 3 0 0 3 3 3 0 Phage protein Gp19/Gp15/Gp42 DUF2576 PF10845.3 CCF48019.1 - 0.49 9.6 1.8 1.2 8.4 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Mus7 PF09462.5 CCF48020.1 - 3.5e-179 597.6 0.0 4.7e-179 597.1 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Sod_Fe_C PF02777.13 CCF48021.1 - 9.4e-35 118.6 0.1 1.7e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCF48021.1 - 1.2e-31 108.7 3.6 1.9e-31 108.1 1.9 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 CCF48021.1 - 3 7.8 6.0 23 4.9 0.6 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Adaptin_binding PF10199.4 CCF48022.1 - 1.2e-31 109.7 0.1 2.8e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Lyase_1 PF00206.15 CCF48023.1 - 4e-23 82.0 0.0 6.5e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCF48023.1 - 2.7e-15 56.1 0.1 5.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Adaptin_N PF01602.15 CCF48024.1 - 4e-151 503.9 7.7 5.2e-151 503.5 5.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCF48024.1 - 8.7e-28 97.3 1.5 1.4e-24 86.9 0.0 3.6 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCF48024.1 - 4.6e-17 62.0 7.4 4.8e-08 33.1 0.0 5.6 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.17 CCF48024.1 - 2.3e-10 39.6 0.7 0.007 16.3 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 CCF48024.1 - 1.4e-05 25.4 1.6 0.24 11.9 0.0 6.2 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.3 CCF48024.1 - 0.00063 19.1 0.0 1.5 8.1 0.0 3.2 3 0 0 3 3 3 2 CLASP N terminal RrnaAD PF00398.15 CCF48025.1 - 5.3e-56 189.5 0.0 7.3e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCF48025.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF48025.1 - 0.0003 20.1 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCF48025.1 - 0.00054 20.5 0.0 0.00098 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF48025.1 - 0.0014 19.0 0.0 0.0026 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCF48025.1 - 0.0021 17.1 0.0 0.017 14.1 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 CCF48025.1 - 0.003 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 CCF48025.1 - 0.0043 17.4 0.0 0.0081 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF48025.1 - 0.0068 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCF48025.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 CCF48025.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 CCF48025.1 - 0.067 12.3 0.0 0.16 11.0 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Metallophos PF00149.23 CCF48026.1 - 1.4e-42 145.4 0.1 1.8e-42 145.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNA_pol_Rpb2_6 PF00562.23 CCF48027.1 - 1.6e-122 408.9 0.0 2.7e-122 408.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCF48027.1 - 6.7e-60 201.4 0.2 2.5e-59 199.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCF48027.1 - 2.1e-35 121.8 0.6 4.2e-35 120.8 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCF48027.1 - 6.3e-27 93.6 0.1 1.6e-26 92.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCF48027.1 - 2.4e-24 84.8 0.8 8.6e-24 83.1 0.2 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCF48027.1 - 1.2e-20 73.0 0.0 2.6e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCF48027.1 - 6.3e-12 45.2 0.1 1.7e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_clus PF00172.13 CCF48028.1 - 6.9e-09 35.4 12.7 1.2e-08 34.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF48028.1 - 0.00027 19.9 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1620 PF07774.8 CCF48029.1 - 1.5e-54 184.5 0.0 2.2e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CCF48029.1 - 2.5e-10 40.2 3.9 7.1e-05 22.3 0.9 4.3 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 CCF48029.1 - 1.3e-07 30.8 0.1 0.56 9.8 0.0 5.6 6 0 0 6 6 6 3 PQQ enzyme repeat PQQ_3 PF13570.1 CCF48029.1 - 0.052 13.8 2.3 6.2 7.2 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain DUF482 PF04339.7 CCF48029.1 - 0.081 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 HLH PF00010.21 CCF48030.1 - 2.2e-13 49.6 0.2 5e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4423 PF14394.1 CCF48030.1 - 0.1 12.1 0.4 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) eIF-5a PF01287.15 CCF48032.1 - 2e-29 101.3 0.4 2.8e-29 100.8 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCF48032.1 - 0.0001 21.8 0.5 0.00026 20.5 0.4 1.7 1 0 0 1 1 1 1 KOW motif Dus PF01207.12 CCF48034.1 - 5.4e-43 146.9 0.1 6e-24 84.4 0.0 3.0 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) ASF1_hist_chap PF04729.8 CCF48035.1 - 4.3e-67 224.5 0.1 4.9e-67 224.3 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone OGFr_III PF04680.8 CCF48037.1 - 0.18 11.9 2.9 0.23 11.6 0.3 2.3 2 0 0 2 2 2 0 Opioid growth factor receptor repeat RhoGEF PF00621.15 CCF48039.1 - 1.4e-44 152.1 0.1 2.6e-44 151.2 0.0 1.5 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 CCF48039.1 - 9.5e-19 67.0 10.5 2.3e-18 65.8 7.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 CCF48039.1 - 2e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCF48039.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain FYVE_2 PF02318.11 CCF48039.1 - 0.46 10.4 7.3 1 9.3 5.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger RRM_1 PF00076.17 CCF48041.1 - 4.6e-33 112.6 0.0 4.1e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48041.1 - 2.9e-28 97.6 0.0 6.5e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48041.1 - 1.4e-11 44.0 0.0 6.4e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 CCF48042.1 - 2.1e-60 202.6 0.0 7.2e-45 152.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF48042.1 - 2.6e-07 30.7 5.1 0.01 15.8 0.1 4.7 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CCF48042.1 - 1e-06 29.5 0.0 0.0082 16.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCF48042.1 - 7.1e-06 25.7 0.0 0.017 14.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCF48042.1 - 1.4e-05 24.9 0.0 0.035 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCF48042.1 - 1.7e-05 24.9 0.1 0.0055 16.8 0.0 3.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCF48042.1 - 4.1e-05 22.7 0.0 0.0054 15.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CCF48042.1 - 8e-05 22.1 0.2 0.002 17.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CCF48042.1 - 0.00017 21.6 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.17 CCF48042.1 - 0.00043 20.1 0.0 0.28 11.0 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 CCF48042.1 - 0.00089 19.1 0.1 0.2 11.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CCF48042.1 - 0.00096 18.8 0.1 0.0067 16.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 CCF48042.1 - 0.001 18.5 0.1 0.0032 16.8 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein DUF815 PF05673.8 CCF48042.1 - 0.0011 17.9 0.0 1.6 7.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 CCF48042.1 - 0.0022 17.5 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain KaiC PF06745.8 CCF48042.1 - 0.0024 17.0 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.1 CCF48042.1 - 0.0028 17.6 1.8 0.19 11.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 CCF48042.1 - 0.0031 17.4 0.0 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CCF48042.1 - 0.0031 16.6 1.4 0.5 9.4 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin Vps4_C PF09336.5 CCF48042.1 - 0.004 17.0 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CCF48042.1 - 0.0045 15.7 0.0 0.031 12.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 CCF48042.1 - 0.0048 17.1 0.0 0.16 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCF48042.1 - 0.0063 16.6 0.0 0.079 13.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 CCF48042.1 - 0.0081 15.0 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 CCF48042.1 - 0.012 14.7 0.4 0.046 12.8 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CCF48042.1 - 0.02 14.5 1.3 3.1 7.4 0.0 3.9 4 0 0 4 4 4 0 NACHT domain AAA_3 PF07726.6 CCF48042.1 - 0.029 13.9 0.0 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CCF48042.1 - 0.034 13.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CCF48042.1 - 0.037 13.2 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CDC48_2 PF02933.12 CCF48042.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_24 PF13479.1 CCF48042.1 - 0.048 13.2 0.2 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCF48042.1 - 0.075 11.8 0.0 1.4 7.6 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain RhoGEF PF00621.15 CCF48043.1 - 2.6e-44 151.2 0.1 7.5e-44 149.7 0.1 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CCF48043.1 - 4.3e-42 142.9 0.3 9.9e-42 141.7 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 CCF48043.1 - 2.5e-34 117.1 0.1 4.8e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 CCF48043.1 - 5.3e-09 35.6 0.2 1.2e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 CCF48043.1 - 0.00015 21.8 0.1 0.00034 20.7 0.1 1.6 1 0 0 1 1 1 1 PH domain 4HB_MCP_1 PF12729.2 CCF48043.1 - 5.3 6.3 9.1 0.62 9.4 1.5 2.6 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction zf-RanBP PF00641.13 CCF48044.1 - 0.0061 15.6 2.0 0.014 14.5 1.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Arteri_nucleo PF01481.11 CCF48045.1 - 0.08 13.0 0.3 0.08 13.0 0.2 2.0 2 1 0 3 3 3 0 Arterivirus nucleocapsid protein VWA_2 PF13519.1 CCF48046.1 - 5e-16 59.2 0.2 5e-16 59.2 0.2 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 CCF48046.1 - 1.6e-09 37.6 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 CCF48046.1 - 1.1e-06 28.4 0.3 2.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CCF48046.1 - 1.5e-06 27.2 31.7 3.6e-05 22.9 1.0 4.3 4 0 0 4 4 4 3 Ubiquitin interaction motif CAF1 PF04857.15 CCF48047.1 - 5.2e-65 219.3 0.0 7.5e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease UQ_con PF00179.21 CCF48048.1 - 2.9e-46 156.3 0.0 3.3e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF48048.1 - 0.0058 16.3 0.1 0.017 14.8 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B Apc1 PF12859.2 CCF48049.1 - 4.2e-14 52.6 0.3 3e-13 49.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CCF48049.1 - 5.6e-07 29.4 17.4 0.37 11.1 0.1 6.3 6 0 0 6 6 6 4 Proteasome/cyclosome repeat Thioredoxin PF00085.15 CCF48050.1 - 6.2e-61 202.5 1.1 1.2e-31 108.4 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CCF48050.1 - 4.9e-41 140.5 1.8 1.4e-29 103.2 0.4 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF48050.1 - 2.5e-12 46.7 0.5 0.0066 16.5 0.0 4.6 4 2 1 5 5 5 3 Thioredoxin-like Thioredoxin_7 PF13899.1 CCF48050.1 - 2.7e-11 43.3 0.0 3.6e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CCF48050.1 - 3.5e-11 43.2 2.3 0.0005 20.2 0.0 4.5 4 2 0 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.12 CCF48050.1 - 2.9e-10 39.4 2.5 4.7e-10 38.7 1.7 1.2 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 CCF48050.1 - 1e-05 25.1 1.7 0.1 12.3 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CCF48050.1 - 1.2e-05 24.9 3.3 0.019 14.4 0.0 3.3 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 CCF48050.1 - 0.00013 22.0 1.6 0.1 12.6 0.0 3.3 4 1 0 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 CCF48050.1 - 0.012 15.4 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain EF1G PF00647.14 CCF48051.1 - 3.3e-46 155.4 0.1 6.6e-46 154.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 CCF48051.1 - 5.7e-11 42.4 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCF48051.1 - 4e-10 39.5 0.0 1.3e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCF48051.1 - 1.2e-08 34.7 0.0 2.9e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCF48051.1 - 1.8e-08 34.4 0.0 4.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCF48051.1 - 3.5e-06 27.4 0.0 7.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCF48051.1 - 4.4e-06 26.5 0.0 9.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CPDase PF07823.6 CCF48052.1 - 2.7e-29 102.0 0.0 3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CCF48052.1 - 0.0005 19.8 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Telomere_Sde2 PF13019.1 CCF48052.1 - 0.073 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Telomere stability and silencing ubiquitin PF00240.18 CCF48053.1 - 6.2e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCF48053.1 - 3e-31 106.7 9.3 4.8e-31 106.1 6.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCF48053.1 - 6.4e-20 70.6 0.7 8.8e-20 70.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCF48053.1 - 8.2e-06 25.9 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCF48053.1 - 0.00017 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCF48053.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCF48053.1 - 0.016 15.3 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCF48053.1 - 0.31 10.8 1.7 0.84 9.4 0.0 2.1 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 CCF48053.1 - 0.81 9.0 3.0 1.2 8.5 2.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase zf-C2H2_2 PF12756.2 CCF48054.1 - 4e-37 126.3 3.2 2.5e-28 98.1 0.0 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCF48054.1 - 9.8e-11 41.4 18.4 2.7e-08 33.7 3.6 5.2 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF48054.1 - 1e-09 38.2 5.2 3.6e-09 36.4 1.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 CCF48054.1 - 0.0031 17.1 0.7 0.016 14.9 0.5 2.2 1 0 0 1 1 1 1 DBF zinc finger AKAP95 PF04988.7 CCF48054.1 - 0.0095 15.7 2.0 4.8 6.9 0.0 2.7 1 1 1 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CCF48054.1 - 0.011 16.0 15.0 0.75 10.2 0.3 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCF48054.1 - 0.026 14.8 17.6 0.22 11.9 0.5 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCF48054.1 - 0.035 14.0 7.8 0.045 13.6 0.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF48054.1 - 0.58 10.5 0.0 0.58 10.5 0.0 4.3 5 0 0 5 5 5 0 Zinc-finger double domain DENN PF02141.16 CCF48055.1 - 0.023 14.3 2.2 0.28 10.8 0.1 2.4 2 0 0 2 2 2 0 DENN (AEX-3) domain Complex1_LYR PF05347.10 CCF48056.1 - 5.6e-06 26.0 0.6 8.6e-06 25.4 0.4 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCF48056.1 - 5.8e-05 23.2 0.5 0.00012 22.1 0.2 1.6 1 1 0 1 1 1 1 Complex1_LYR-like E1-E2_ATPase PF00122.15 CCF48057.1 - 4e-19 68.5 0.0 2.8e-18 65.7 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCF48057.1 - 5.6e-17 62.8 0.0 8.7e-16 58.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF48057.1 - 2.2e-10 41.0 0.1 5.5e-10 39.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF48057.1 - 9.6e-06 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF48057.1 - 0.0097 15.5 0.1 0.025 14.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M3 PF01432.15 CCF48058.1 - 1.8e-117 393.1 0.0 2.5e-117 392.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF4344 PF14247.1 CCF48058.1 - 0.53 9.9 1.7 39 3.8 0.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4344) rve PF00665.21 CCF48061.1 - 5.4e-15 55.5 0.0 8.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF48061.1 - 0.0024 17.3 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF48061.1 - 0.0031 17.1 0.0 0.0084 15.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain TFIIE_beta PF02186.10 CCF48061.1 - 0.019 14.9 0.1 5.4 7.0 0.0 3.1 3 0 0 3 3 3 0 TFIIE beta subunit core domain MFS_1 PF07690.11 CCF48062.1 - 1.6e-28 99.4 45.3 1.6e-28 99.4 31.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Lipase_3 PF01764.20 CCF48063.1 - 6.4e-17 61.4 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Myb_DNA-bind_5 PF13873.1 CCF48064.1 - 6.1e-05 22.8 2.4 0.00015 21.5 1.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 CCF48065.1 - 1.3e-12 47.5 0.0 8.4e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease ABC1 PF03109.11 CCF48066.1 - 2.9e-29 101.4 0.0 6.8e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 CCF48066.1 - 4.6e-19 67.5 0.4 1.1e-18 66.3 0.3 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Mid1 PF12929.2 CCF48067.1 - 5.1e-71 239.6 3.4 6.7e-71 239.2 2.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component fn3 PF00041.16 CCF48067.1 - 0.013 15.6 0.3 0.25 11.4 0.0 2.5 2 0 0 2 2 2 0 Fibronectin type III domain DUF1180 PF06679.7 CCF48067.1 - 0.085 12.7 0.4 0.21 11.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Fz PF01392.17 CCF48067.1 - 0.46 10.8 4.9 0.36 11.2 0.9 2.3 2 1 0 2 2 2 0 Fz domain Hep_59 PF07052.6 CCF48068.1 - 2.1e-23 82.6 0.5 4.5e-23 81.5 0.0 1.7 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Glutaredoxin PF00462.19 CCF48069.1 - 7.2e-09 35.5 0.0 9.1e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 CCF48069.1 - 0.0018 18.4 0.0 0.0022 18.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF48069.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain rve PF00665.21 CCF48070.1 - 3.3e-10 40.0 0.0 6.2e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 CCF48071.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Bcl-2_BAD PF10514.4 CCF48074.1 - 1.6 8.6 7.4 0.81 9.6 0.4 2.3 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD rve PF00665.21 CCF48075.1 - 3.8e-06 27.0 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RRM_5 PF13893.1 CCF48076.1 - 4.9e-18 64.7 0.0 1.3e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF48076.1 - 2.6e-16 59.0 0.3 1.2e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48076.1 - 3.7e-10 39.6 0.1 4.3e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF48076.1 - 0.036 13.9 0.1 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DARPP-32 PF05395.7 CCF48077.1 - 0.09 12.9 0.5 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RVT_2 PF07727.9 CCF48078.1 - 8e-38 129.8 0.0 9.3e-38 129.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_AP2 PF14657.1 CCF48079.1 - 0.082 12.7 0.7 0.16 11.7 0.5 1.4 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain SLX9 PF15341.1 CCF48079.1 - 0.28 11.6 5.0 0.47 10.8 3.4 1.3 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DEAD PF00270.24 CCF48080.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase UPF0203 PF05254.7 CCF48086.1 - 0.0057 16.4 3.2 0.039 13.7 2.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.8 CCF48086.1 - 0.025 14.5 2.1 0.078 12.9 1.4 1.8 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.5 CCF48086.1 - 0.12 12.1 4.8 0.25 11.1 3.3 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CCF48086.1 - 0.34 10.9 2.4 0.52 10.3 1.7 1.4 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_6 PF12697.2 CCF48087.1 - 1e-15 58.2 2.2 1.6e-15 57.6 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF48087.1 - 6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF48087.1 - 3.7e-05 23.5 0.0 0.00077 19.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 CCF48088.1 - 0.035 13.2 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain SET PF00856.23 CCF48089.1 - 3.9e-25 89.0 0.1 3.9e-25 89.0 0.0 3.0 2 2 0 2 2 2 1 SET domain SRI PF08236.6 CCF48089.1 - 6e-19 67.7 1.0 1.5e-18 66.4 0.7 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.27 CCF48090.1 - 6e-18 63.9 0.5 3.4e-08 33.0 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCF48090.1 - 5.1e-05 22.6 0.0 0.0033 16.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 CCF48090.1 - 0.028 14.0 0.5 16 5.2 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MoCF_biosynth PF00994.19 CCF48090.1 - 0.043 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain FA_desaturase PF00487.19 CCF48091.1 - 1.9e-32 112.7 24.8 5.3e-32 111.2 17.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCF48091.1 - 1.1e-13 50.7 0.0 2.8e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rubella_E2 PF05749.6 CCF48091.1 - 0.12 11.5 2.5 0.21 10.7 1.7 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Amidohydro_3 PF07969.6 CCF48093.1 - 2.7e-68 231.0 0.2 3.7e-68 230.6 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Methyltransf_23 PF13489.1 CCF48093.1 - 1.9e-10 40.7 0.0 4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF48093.1 - 8.3e-09 36.0 0.2 2.4e-08 34.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF48093.1 - 1.8e-06 28.3 0.0 3.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF48093.1 - 1.2e-05 24.9 0.0 7.7e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCF48093.1 - 0.0003 19.9 0.0 0.00059 19.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CCF48093.1 - 0.0026 18.0 0.0 0.0057 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Amidohydro_5 PF13594.1 CCF48093.1 - 0.0038 17.0 0.2 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 Amidohydrolase RrnaAD PF00398.15 CCF48093.1 - 0.0051 15.8 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 CCF48093.1 - 0.0079 16.6 0.0 0.047 14.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCF48093.1 - 0.014 16.2 0.0 0.037 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCF48093.1 - 0.023 14.0 0.0 0.056 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CCF48093.1 - 0.024 14.6 0.0 0.083 12.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Amidohydro_1 PF01979.15 CCF48093.1 - 0.054 13.1 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family PCMT PF01135.14 CCF48093.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 CCF48093.1 - 0.17 11.0 0.0 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB MetW PF07021.7 CCF48093.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCI PF01399.22 CCF48094.1 - 2.4e-10 40.6 0.0 6.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain Ras PF00071.17 CCF48095.1 - 2.3e-51 173.3 0.0 2.7e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF48095.1 - 3.7e-17 62.9 0.0 5.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF48095.1 - 2.9e-06 26.6 0.0 4.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CCF48095.1 - 0.0099 15.3 0.0 4.2 6.8 0.0 2.6 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 CCF48095.1 - 0.01 15.2 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCF48095.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_pol PF00940.14 CCF48096.1 - 9.8e-157 521.5 0.0 1.6e-156 520.8 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCF48096.1 - 4.2e-79 266.0 1.9 8.4e-79 265.1 1.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 CCF48096.1 - 0.0027 17.6 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 CCF48096.1 - 0.11 12.7 1.9 1.1 9.6 0.2 3.7 4 1 0 4 4 4 0 Pentatricopeptide repeat domain TauD PF02668.11 CCF48097.1 - 2.3e-27 96.2 0.0 5.7e-27 95.0 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Gp_dh_C PF02800.15 CCF48098.1 - 1.9e-75 251.6 0.0 2.7e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCF48098.1 - 1.6e-58 196.9 0.4 2.7e-58 196.2 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Chromo PF00385.19 CCF48100.1 - 1.2e-11 44.0 0.1 1.7e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_2 PF07727.9 CCF48103.1 - 4.6e-27 94.5 0.0 6.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF48104.1 - 6.2e-35 120.3 0.0 8.3e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF48104.1 - 0.046 13.0 0.1 0.21 10.9 0.0 1.9 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.1 CCF48105.1 - 0.0038 16.6 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CCF48105.1 - 0.13 12.2 1.7 0.13 12.2 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle Dicty_REP PF05086.7 CCF48105.1 - 0.62 7.7 4.5 0.61 7.7 3.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 CCF48107.1 - 1.7e-74 250.2 2.0 1.8e-74 250.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48107.1 - 1.4e-52 178.3 0.1 1.4e-52 178.3 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 CCF48107.1 - 6.5e-21 74.5 0.0 2.2e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CCF48107.1 - 1.1e-09 38.4 1.2 2.4e-09 37.3 0.9 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CCF48107.1 - 3.1e-07 29.6 0.0 5.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CCF48107.1 - 0.00027 21.1 0.8 0.022 15.0 0.2 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain APH PF01636.18 CCF48107.1 - 0.0027 17.4 0.0 0.009 15.7 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sen15 PF09631.5 CCF48108.1 - 3.3e-11 43.3 0.0 5.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein EF-hand_1 PF00036.27 CCF48110.1 - 0.0096 15.1 0.0 0.027 13.7 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CCF48110.1 - 0.035 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 CCF48110.1 - 0.099 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.20 CCF48111.1 - 5.8e-45 153.4 0.0 2.3e-44 151.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48111.1 - 6.3e-24 84.4 0.0 1.4e-23 83.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCF48111.1 - 0.086 12.1 0.3 3.7 6.8 0.0 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL RPA_interact_C PF14768.1 CCF48114.1 - 0.0033 17.8 0.3 0.0052 17.1 0.2 1.3 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Lar_restr_allev PF14354.1 CCF48114.1 - 0.051 13.8 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar RRM_1 PF00076.17 CCF48115.1 - 2.4e-23 81.5 0.0 3.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48115.1 - 1.5e-18 66.4 0.0 2.1e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48115.1 - 9.3e-11 41.4 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytadhesin_P30 PF07271.6 CCF48115.1 - 0.00014 21.2 10.1 0.00017 20.9 7.0 1.1 1 0 0 1 1 1 1 Cytadhesin P30/P32 Glyoxal_oxid_N PF07250.6 CCF48116.1 - 7.1e-34 116.9 0.1 2.2e-30 105.5 0.1 3.6 2 2 1 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCF48116.1 - 1.5e-19 69.8 0.2 3.5e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) EphA2_TM PF14575.1 CCF48116.1 - 0.19 12.1 0.8 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_L11_N PF03946.9 CCF48118.1 - 2.5e-18 65.2 0.1 4.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCF48118.1 - 7.9e-12 45.1 0.2 1.3e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.3 CCF48118.1 - 0.44 10.6 2.4 0.86 9.7 1.6 1.4 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M WD40 PF00400.27 CCF48119.1 - 1.1e-63 208.9 23.2 1.9e-11 43.3 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCF48119.1 - 3.2e-05 22.2 8.8 0.036 12.2 1.8 3.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCF48119.1 - 0.054 12.2 1.4 2.6 6.7 0.0 2.6 1 1 1 2 2 2 0 Nup133 N terminal like PD40 PF07676.7 CCF48119.1 - 0.059 13.0 1.4 41 3.9 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Thymidylat_synt PF00303.14 CCF48120.1 - 3.5e-112 373.8 0.0 4.9e-112 373.3 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 CCF48120.1 - 5.8e-29 101.2 0.0 4.6e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Sec23_trunk PF04811.10 CCF48121.1 - 1.3e-57 194.9 0.0 4.4e-57 193.2 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCF48121.1 - 2.6e-24 84.6 0.1 4.5e-24 83.8 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCF48121.1 - 7.4e-20 71.2 0.0 1.7e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCF48121.1 - 1.2e-15 56.7 2.2 2.6e-15 55.6 1.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCF48121.1 - 0.00016 21.2 0.0 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat peroxidase PF00141.18 CCF48122.1 - 5.9e-49 166.6 0.0 1e-48 165.8 0.0 1.4 1 0 0 1 1 1 1 Peroxidase COX_ARM PF06481.9 CCF48122.1 - 0.39 10.4 6.1 2.8 7.6 0.1 2.8 3 0 0 3 3 3 0 COX Aromatic Rich Motif IGPS PF00218.16 CCF48123.1 - 4.9e-94 314.1 0.0 2.1e-92 308.8 0.0 2.2 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 CCF48123.1 - 9.3e-52 175.4 0.0 8.4e-47 159.2 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 CCF48123.1 - 1.8e-45 154.7 0.0 3.3e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCF48123.1 - 3.1e-05 23.5 0.1 0.00011 21.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 CCF48123.1 - 0.0089 15.5 0.0 0.031 13.7 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 CCF48123.1 - 0.0099 14.8 0.1 3.3 6.6 0.0 2.8 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase HEAT PF02985.17 CCF48124.1 - 3.8e-20 70.1 14.9 0.00037 20.3 0.0 10.1 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.1 CCF48124.1 - 1.1e-17 64.0 14.6 4.3e-08 33.3 0.0 7.3 2 1 4 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CCF48124.1 - 6.8e-17 61.4 20.6 2.3e-08 34.2 0.0 8.8 10 1 1 11 11 10 5 HEAT-like repeat IBN_N PF03810.14 CCF48124.1 - 1.2e-11 44.3 0.3 1e-09 38.1 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 CCF48124.1 - 2.2e-06 27.2 14.0 0.0095 15.7 0.0 5.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CCF48124.1 - 0.0048 15.2 0.3 0.26 9.5 0.0 3.5 2 2 1 3 3 3 1 Adaptin N terminal region TIP120 PF08623.5 CCF48124.1 - 0.013 15.0 0.2 0.44 10.0 0.0 2.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) TFCD_C PF12612.3 CCF48124.1 - 0.02 14.3 1.5 1.3 8.3 0.1 3.4 4 1 0 4 4 4 0 Tubulin folding cofactor D C terminal CLASP_N PF12348.3 CCF48124.1 - 0.03 13.6 0.1 49 3.1 0.0 4.1 4 1 1 5 5 5 0 CLASP N terminal Proteasom_PSMB PF10508.4 CCF48124.1 - 0.059 11.6 0.1 0.32 9.2 0.0 2.1 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit MMS19_N PF14500.1 CCF48124.1 - 0.14 11.4 0.2 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_PBS PF03130.11 CCF48124.1 - 0.17 12.4 5.6 25 5.7 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RVT_1 PF00078.22 CCF48126.1 - 7.6e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF48127.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain D5_N PF08706.6 CCF48127.1 - 0.027 14.5 0.0 0.063 13.3 0.0 1.5 2 0 0 2 2 2 0 D5 N terminal like Laminin_G_3 PF13385.1 CCF48128.1 - 0.041 14.1 0.2 0.041 14.1 0.2 1.1 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily rve PF00665.21 CCF48129.1 - 1.4e-08 34.8 0.0 1.7e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain PepX_N PF09168.5 CCF48131.1 - 0.13 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal RVT_2 PF07727.9 CCF48132.1 - 5.6e-41 140.1 0.5 7.1e-41 139.7 0.4 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF48133.1 - 4.7e-50 169.8 0.1 1.8e-37 128.6 0.0 2.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF48135.1 - 3.3e-05 22.9 0.2 4.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CCF48136.1 - 2.2e-11 43.2 0.1 3.8e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mit_ribos_Mrp51 PF11709.3 CCF48137.1 - 0.027 13.6 0.5 0.035 13.3 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Imm25 PF15571.1 CCF48137.1 - 0.14 12.2 0.6 0.29 11.2 0.4 1.5 1 0 0 1 1 1 0 Immunity protein 25 Syntaxin PF00804.20 CCF48137.1 - 0.18 12.0 3.6 0.45 10.6 2.0 2.2 1 1 1 2 2 2 0 Syntaxin RVT_1 PF00078.22 CCF48138.1 - 1.5e-20 73.5 0.0 5.5e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CCF48138.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease FimH_man-bind PF09160.5 CCF48138.1 - 0.0042 16.9 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 FimH, mannose binding gag-asp_proteas PF13975.1 CCF48138.1 - 0.0073 16.1 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF4256 PF14066.1 CCF48138.1 - 0.036 13.5 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) rve_3 PF13683.1 CCF48139.1 - 7.3e-06 25.4 1.3 2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain rve PF00665.21 CCF48139.1 - 6.9e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CCF48139.1 - 0.00011 21.9 1.1 0.00035 20.3 0.8 1.9 1 0 0 1 1 1 1 Zinc knuckle DUF883 PF05957.8 CCF48142.1 - 2.3e-06 27.9 29.6 0.014 15.7 3.1 4.3 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) LEA_4 PF02987.11 CCF48142.1 - 0.0057 16.5 22.6 0.012 15.4 5.5 4.5 4 2 1 5 5 5 2 Late embryogenesis abundant protein YtxH PF12732.2 CCF48142.1 - 0.088 13.1 25.7 1.5e+04 -11.1 17.8 4.4 1 1 0 1 1 1 0 YtxH-like protein Uds1 PF15456.1 CCF48142.1 - 0.49 10.3 9.4 0.12 12.4 1.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Apolipoprotein PF01442.13 CCF48142.1 - 0.85 9.0 16.7 3.8 6.9 2.4 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Chlorosome_CsmC PF11098.3 CCF48142.1 - 1.3 8.6 23.5 0.28 10.9 6.9 3.7 1 1 2 3 3 3 0 Chlorosome envelope protein C EspB PF05802.6 CCF48142.1 - 2.5 6.9 42.5 1.3 7.9 5.4 3.1 1 1 2 3 3 3 0 Enterobacterial EspB protein Phage_Coat_Gp8 PF05371.7 CCF48142.1 - 2.5 7.7 0.0 2.5 7.7 0.0 4.2 4 1 1 5 5 5 0 Phage major coat protein, Gp8 DivIVA PF05103.8 CCF48142.1 - 9.8 6.2 36.7 3.9 7.5 5.0 4.9 1 1 3 4 4 4 0 DivIVA protein PG_binding_2 PF08823.6 CCF48143.1 - 0.086 12.9 0.1 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Putative peptidoglycan binding domain NYN PF01936.13 CCF48145.1 - 5.8e-27 94.7 0.0 1.2e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 NYN domain SLH PF00395.15 CCF48145.1 - 0.31 10.8 1.7 1.2e+02 2.5 0.0 3.8 4 0 0 4 4 4 0 S-layer homology domain RVT_1 PF00078.22 CCF48148.1 - 6.1e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MTHFR PF02219.12 CCF48149.1 - 2.6e-111 371.3 0.0 4e-111 370.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AP_endonuc_2 PF01261.19 CCF48149.1 - 0.065 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF3479 PF11965.3 CCF48149.1 - 0.084 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Skp1 PF01466.14 CCF48150.1 - 9.6e-40 134.4 0.9 1.5e-39 133.8 0.6 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCF48150.1 - 3.1e-25 88.0 0.2 7.6e-25 86.7 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CCF48150.1 - 0.013 15.4 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Med12 PF09497.5 CCF48151.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Paf1 PF03985.8 CCF48152.1 - 8.5e-37 126.9 22.7 4.8e-34 117.8 0.0 4.2 2 2 2 4 4 4 2 Paf1 4HBT PF03061.17 CCF48153.1 - 2.9e-05 24.0 0.1 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily RVT_1 PF00078.22 CCF48155.1 - 9e-15 54.6 0.1 3.9e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PIP5K PF01504.13 CCF48156.1 - 4.5e-63 212.6 0.0 8.6e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCF48156.1 - 7.5e-24 84.1 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCF48156.1 - 4.7e-16 58.4 10.9 1.3e-15 57.0 7.5 1.8 1 0 0 1 1 1 1 FYVE zinc finger TRAP_alpha PF03896.11 CCF48156.1 - 0.84 8.5 6.1 2 7.3 4.2 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ytp1 PF10355.4 CCF48156.1 - 2.6 7.1 0.0 4.3 6.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) Cpn60_TCP1 PF00118.19 CCF48157.1 - 2.7e-147 491.2 1.0 3.2e-147 491.0 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family A_deaminase PF00962.17 CCF48158.1 - 8.6e-38 130.0 0.0 1.4e-37 129.3 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase LRR_6 PF13516.1 CCF48159.1 - 1.2e-12 46.4 3.1 0.33 11.1 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.2 CCF48159.1 - 9.6e-09 34.8 0.0 2.4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 CCF48159.1 - 2.1e-07 30.3 2.9 0.034 13.7 0.1 5.0 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CCF48159.1 - 0.00015 21.4 11.9 3.4 8.2 0.2 7.3 7 1 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 CCF48159.1 - 0.00017 21.1 7.9 7.9 6.9 0.1 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat F-box PF00646.28 CCF48159.1 - 0.0015 18.1 5.7 0.021 14.4 0.0 3.8 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.1 CCF48159.1 - 0.0058 16.3 9.3 13 5.6 0.2 5.3 4 2 0 4 4 4 2 Leucine rich repeat Lactamase_B PF00753.22 CCF48160.1 - 1.2e-27 96.8 2.4 1.6e-27 96.4 1.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCF48160.1 - 0.00034 20.1 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3970 PF13113.1 CCF48160.1 - 0.13 11.9 0.0 0.74 9.5 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) Vsr PF03852.10 CCF48161.1 - 0.07 12.7 0.5 0.3 10.7 0.1 2.2 3 0 0 3 3 3 0 DNA mismatch endonuclease Vsr Ribosomal_S7 PF00177.16 CCF48162.1 - 2.5e-40 137.4 0.8 3e-40 137.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e WD40 PF00400.27 CCF48163.1 - 5e-63 206.9 12.5 5.4e-10 38.7 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 CCF48163.1 - 2.9e-06 26.8 0.3 5.2e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CCF48163.1 - 0.0012 18.5 0.0 0.061 13.0 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCF48163.1 - 0.0031 16.9 0.1 11 5.6 0.0 4.6 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 CCF48163.1 - 0.06 12.3 1.7 0.076 12.0 0.0 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CDC45 PF02724.9 CCF48165.1 - 0.04 11.9 12.7 0.048 11.6 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CCF48165.1 - 0.053 13.0 7.9 0.07 12.6 5.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 CCF48165.1 - 0.082 12.3 9.2 0.092 12.1 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2201_N PF13203.1 CCF48165.1 - 0.17 11.0 9.5 0.2 10.8 6.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Paf1 PF03985.8 CCF48165.1 - 0.24 10.0 15.5 0.3 9.7 10.7 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 CCF48165.1 - 0.26 9.1 15.2 0.28 9.0 10.5 1.0 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.1 CCF48165.1 - 0.48 8.8 7.1 0.54 8.7 5.0 1.0 1 0 0 1 1 1 0 Raftlin Daxx PF03344.10 CCF48165.1 - 0.61 8.5 15.8 0.68 8.3 11.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF4407 PF14362.1 CCF48165.1 - 0.71 8.7 7.1 0.87 8.4 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 CCF48165.1 - 2.1 7.6 17.9 2.5 7.4 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 CCF48165.1 - 2.7 7.7 8.5 3.5 7.4 5.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TRAP_alpha PF03896.11 CCF48165.1 - 3 6.7 5.7 3.7 6.4 4.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Suf PF05843.9 CCF48165.1 - 3.7 7.2 8.1 4.2 7.0 5.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CCF48165.1 - 3.8 7.3 5.8 4.6 7.0 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.5 CCF48165.1 - 4 7.4 15.3 5 7.1 10.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3c_N PF05470.7 CCF48165.1 - 4 5.4 9.8 4.3 5.3 6.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SRP72 PF08492.7 CCF48165.1 - 4.3 7.7 8.9 31 5.0 6.2 2.1 1 1 0 1 1 1 0 SRP72 RNA-binding domain Ycf1 PF05758.7 CCF48165.1 - 4.3 4.9 9.6 4.8 4.7 6.7 1.0 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 CCF48165.1 - 5.8 4.6 10.3 6.3 4.5 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 CCF48165.1 - 6 4.8 6.3 7.2 4.5 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AFT PF08731.6 CCF48165.1 - 8.7 6.5 7.5 25 5.1 5.2 1.8 1 1 0 1 1 1 0 Transcription factor AFT RVT_2 PF07727.9 CCF48169.1 - 3.1e-53 180.2 0.0 3.4e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF48170.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF48172.1 - 1.2e-14 54.4 0.3 1.5e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Integrase core domain Guanylin PF02058.10 CCF48172.1 - 0.1 12.7 0.0 0.85 9.7 0.0 2.0 2 0 0 2 2 2 0 Guanylin precursor DUF1342 PF07072.6 CCF48173.1 - 0.11 12.1 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) SNF2_N PF00176.18 CCF48174.1 - 3e-65 219.9 0.1 5.8e-65 219.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCF48174.1 - 3.5e-13 49.4 0.0 7.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CCF48174.1 - 7.4e-10 38.5 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CCF48174.1 - 4e-05 23.3 1.0 0.0001 22.0 0.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCF48174.1 - 8.8e-05 22.1 0.5 8.8e-05 22.1 0.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCF48174.1 - 0.00017 21.5 1.1 0.00017 21.5 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF48174.1 - 0.00023 20.7 0.6 0.00065 19.3 0.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF48174.1 - 0.014 15.0 0.1 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ResIII PF04851.10 CCF48174.1 - 0.047 13.5 0.2 2.3 8.0 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DZR PF12773.2 CCF48174.1 - 0.08 12.7 1.8 3.6 7.4 0.6 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 CCF48174.1 - 7.2 6.5 8.7 0.32 10.8 1.2 2.4 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING PNP_UDP_1 PF01048.15 CCF48175.1 - 6.5e-36 123.4 0.0 7.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF410 PF04190.8 CCF48175.1 - 0.051 13.1 0.8 0.079 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) DUF4193 PF13834.1 CCF48175.1 - 0.2 11.8 0.6 0.53 10.4 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4193) MMR_HSR1 PF01926.18 CCF48176.1 - 6.4e-14 51.9 0.0 7.8e-13 48.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF48176.1 - 0.00013 21.3 0.0 0.0011 18.2 0.0 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCF48176.1 - 0.0034 17.2 0.1 0.02 14.7 0.1 2.2 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CCF48176.1 - 0.008 15.3 0.1 0.017 14.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CCF48176.1 - 0.031 14.7 0.0 0.1 13.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Septin PF00735.13 CCF48176.1 - 0.12 11.3 0.0 0.73 8.7 0.0 2.0 2 0 0 2 2 2 0 Septin NIF PF03031.13 CCF48177.1 - 2.6e-21 75.9 0.0 8.5e-21 74.2 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CCF48177.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain HAD_2 PF13419.1 CCF48177.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 2.2 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase BRCT PF00533.21 CCF48177.1 - 0.086 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DPBB_1 PF03330.13 CCF48178.1 - 7.3e-06 25.9 0.4 1.7e-05 24.7 0.3 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCF48178.1 - 0.0033 17.0 0.1 0.0078 15.8 0.1 1.7 1 1 0 1 1 1 1 Barwin family DUF605 PF04652.11 CCF48178.1 - 1.6 8.0 18.7 2.4 7.4 12.9 1.2 1 0 0 1 1 1 0 Vta1 like MSP1_C PF07462.6 CCF48178.1 - 2.5 6.4 8.6 3.2 6.0 6.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RVT_2 PF07727.9 CCF48184.1 - 1.8e-13 50.0 0.0 2e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CCF48188.1 - 4.1e-06 26.5 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCF48188.1 - 6.1e-06 26.2 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CCF48188.1 - 0.0012 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCF48189.1 - 3e-05 23.7 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCF48189.1 - 4.9e-05 23.2 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CCF48189.1 - 0.0048 17.3 0.0 0.0093 16.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag_pre-integrs PF13976.1 CCF48192.1 - 1.5e-05 24.5 1.2 2.7e-05 23.6 0.8 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF2946 PF11162.3 CCF48195.1 - 0.1 12.8 1.3 0.14 12.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) MAM PF00629.18 CCF48197.1 - 0.046 13.5 0.2 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 MAM domain rve PF00665.21 CCF48198.1 - 6.9e-21 74.5 0.0 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF48198.1 - 0.096 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain zf-C2H2 PF00096.21 CCF48199.1 - 2.3 8.7 6.3 1.7 9.1 0.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type LSM PF01423.17 CCF48200.1 - 5.7e-17 61.0 0.0 8.2e-17 60.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain MFS_1 PF07690.11 CCF48201.1 - 1.4e-30 106.2 25.6 1.4e-30 106.2 17.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF48201.1 - 3.4e-14 52.2 20.7 5.1e-13 48.4 7.3 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Abhydrolase_6 PF12697.2 CCF48203.1 - 9.3e-20 71.4 0.0 1.3e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48203.1 - 7.6e-17 61.4 0.0 5.4e-16 58.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCF48203.1 - 5.9e-09 34.8 0.0 5.7e-07 28.3 0.0 2.3 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CCF48203.1 - 6.4e-08 32.3 0.0 8.4e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CCF48203.1 - 6.2e-07 28.8 0.1 1.7e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 CCF48203.1 - 2.3e-06 27.0 0.0 3.1e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 CCF48203.1 - 8.9e-06 24.2 0.2 0.073 11.3 0.0 2.3 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.6 CCF48203.1 - 2.3e-05 24.2 0.0 7.7e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 CCF48203.1 - 0.0015 18.1 0.0 0.015 14.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 CCF48203.1 - 0.0052 15.4 0.0 0.007 14.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 CCF48203.1 - 0.011 15.2 0.0 0.12 11.9 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCF48203.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase BRCT PF00533.21 CCF48204.1 - 3.3e-23 81.6 0.2 3.9e-09 36.5 0.0 7.0 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCF48204.1 - 2.2e-17 62.6 0.8 3.1e-15 55.7 0.2 4.3 5 0 0 5 5 5 1 twin BRCT domain RRM_1 PF00076.17 CCF48205.1 - 6.8e-13 48.0 0.0 1.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48205.1 - 3.6e-10 39.6 0.0 6.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48205.1 - 2.6e-07 30.3 0.0 4.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCF48205.1 - 1.7e-06 28.3 6.4 1.7e-06 28.3 4.5 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 DUF221 PF02714.10 CCF48206.1 - 2e-86 289.8 18.1 3.5e-86 289.0 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCF48206.1 - 2.9e-37 127.6 1.4 8.9e-37 126.0 1.0 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCF48206.1 - 2.6e-18 66.3 0.0 5.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Beach PF02138.13 CCF48207.1 - 1.4e-103 346.0 0.0 2.2e-103 345.4 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 CCF48207.1 - 3.6e-11 42.4 10.0 1.7e-05 24.4 0.6 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat PH_BEACH PF14844.1 CCF48207.1 - 3.7e-09 36.3 0.0 8.8e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FYVE PF01363.16 CCF48207.1 - 0.00016 21.5 8.2 0.00034 20.4 5.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 CCF48207.1 - 1.7 8.6 7.0 4.8 7.1 4.8 1.8 1 1 0 1 1 1 0 IBR domain HSP20 PF00011.16 CCF48208.1 - 9.3e-18 63.9 0.5 3e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family GvpH PF05455.6 CCF48208.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 GvpH PA14_2 PF10528.4 CCF48208.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 GLEYA domain PI-PLC-X PF00388.14 CCF48209.1 - 0.0048 16.2 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF1995 PF09353.5 CCF48209.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) RAP1 PF07218.6 CCF48209.1 - 1.7 6.6 4.4 2.3 6.2 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BRO1 PF03097.13 CCF48210.1 - 6e-110 367.5 0.0 1e-109 366.7 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCF48210.1 - 1.1e-72 244.5 0.0 2.2e-72 243.5 0.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MCPVI PF02993.9 CCF48210.1 - 1.3 9.1 11.1 5.4 7.1 6.3 2.3 2 0 0 2 2 2 0 Minor capsid protein VI WGG PF10273.4 CCF48211.1 - 2.5e-24 85.1 0.0 3.9e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 T2SM PF04612.7 CCF48211.1 - 0.11 12.2 0.8 0.16 11.7 0.6 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M RRP7 PF12923.2 CCF48211.1 - 0.14 12.1 1.3 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) DUF4167 PF13763.1 CCF48212.1 - 0.086 12.8 3.0 0.26 11.3 2.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) SNN_linker PF09050.5 CCF48212.1 - 1.7 8.2 5.9 9.3 5.8 0.5 3.3 3 0 0 3 3 3 0 Stannin unstructured linker Voltage_CLC PF00654.15 CCF48213.1 - 2.3e-92 309.7 26.0 2.3e-92 309.7 18.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCF48213.1 - 0.00013 21.6 0.1 0.00048 19.8 0.0 2.0 2 0 0 2 2 2 1 CBS domain DASH_Hsk3 PF08227.6 CCF48214.1 - 1.7e-15 56.8 0.9 2.3e-15 56.4 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like LRR_8 PF13855.1 CCF48215.1 - 1.2e-08 34.5 5.1 2.1e-08 33.7 2.3 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 CCF48215.1 - 2e-08 33.6 8.6 1.4e-06 27.7 1.1 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCF48215.1 - 0.027 14.4 5.7 0.89 9.8 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CCF48215.1 - 0.2 11.9 7.6 1.2 9.6 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat UPRTase PF14681.1 CCF48216.1 - 7.6e-79 263.7 0.0 8.7e-79 263.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCF48216.1 - 5.2e-05 22.9 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ESCRT-II PF05871.7 CCF48217.1 - 1.4e-47 161.0 0.1 2.2e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit Pepsin-I3 PF06394.8 CCF48217.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Rxt3 PF08642.5 CCF48218.1 - 1.8e-19 70.0 0.0 1.8e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 MIP-T3 PF10243.4 CCF48218.1 - 2.5e-06 26.2 21.4 2.5e-06 26.2 14.8 3.6 4 0 0 4 4 4 2 Microtubule-binding protein MIP-T3 LCCL PF03815.14 CCF48218.1 - 0.032 14.2 0.0 0.89 9.5 0.0 2.4 2 0 0 2 2 2 0 LCCL domain SAPS PF04499.10 CCF48218.1 - 0.086 11.4 5.3 0.14 10.7 1.6 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DEAD PF00270.24 CCF48219.1 - 1.4e-37 128.7 0.1 2.8e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48219.1 - 4.4e-23 80.9 0.0 2.7e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCF48219.1 - 0.00064 19.5 1.6 0.0023 17.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit FLO_LFY PF01698.11 CCF48219.1 - 0.005 15.7 1.1 0.0094 14.8 0.8 1.3 1 0 0 1 1 1 1 Floricaula / Leafy protein CDC45 PF02724.9 CCF48219.1 - 0.015 13.3 4.0 0.022 12.8 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-CCCH PF00642.19 CCF48220.1 - 1.4e-12 46.9 14.3 1.2e-06 28.0 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CCF48220.1 - 1.5e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF48220.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase2 PF03162.8 CCF48221.1 - 1.3e-48 164.4 0.0 1.5e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCF48221.1 - 4.6e-05 23.7 0.0 0.00042 20.5 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCF48221.1 - 0.0035 16.9 0.0 0.0059 16.1 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF48221.1 - 0.047 13.0 0.0 0.054 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase XPG_N PF00752.12 CCF48222.1 - 2.8e-29 101.3 0.0 5.1e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCF48222.1 - 2.2e-25 88.5 0.0 4.9e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region MFS_1 PF07690.11 CCF48223.1 - 2.9e-44 151.2 45.8 1e-42 146.1 33.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCF48223.1 - 1e-24 86.7 30.7 6.8e-24 83.9 22.0 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCF48223.1 - 3e-10 39.2 38.0 5.1e-10 38.5 10.6 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 CCF48223.1 - 0.95 9.3 7.9 0.43 10.4 0.3 3.2 3 0 0 3 3 3 0 MFS_1 like family Dishevelled PF02377.10 CCF48223.1 - 4.4 7.5 9.9 5.2 7.3 1.8 2.8 2 1 1 3 3 3 0 Dishevelled specific domain Sds3 PF08598.6 CCF48224.1 - 6e-15 55.3 0.0 7.9e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Sds3-like Baculo_PP31 PF05311.6 CCF48224.1 - 0.0015 17.8 1.2 0.0015 17.8 0.8 2.2 2 0 0 2 2 2 2 Baculovirus 33KDa late protein (PP31) DUF566 PF04484.7 CCF48224.1 - 2.7 7.4 17.5 0.18 11.3 6.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF566) Cullin PF00888.17 CCF48225.1 - 2.7e-149 498.4 5.0 5.4e-143 477.6 0.2 2.2 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CCF48225.1 - 5.2e-31 106.2 1.3 1.5e-30 104.7 0.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.5 CCF48225.1 - 0.00052 19.5 0.1 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 IclR helix-turn-helix domain TrmB PF01978.14 CCF48225.1 - 0.021 14.5 0.0 0.73 9.5 0.0 2.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF3658 PF12395.3 CCF48225.1 - 0.024 14.1 0.2 0.07 12.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function MarR_2 PF12802.2 CCF48225.1 - 0.029 14.0 0.2 6.2 6.5 0.0 2.7 2 0 0 2 2 2 0 MarR family DDRGK PF09756.4 CCF48225.1 - 0.032 13.6 6.6 0.023 14.0 0.9 2.6 2 0 0 2 2 2 0 DDRGK domain HTH_AsnC-type PF13404.1 CCF48225.1 - 0.063 12.8 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Opi1 PF08618.5 CCF48226.1 - 3.5e-160 533.6 6.3 3.5e-160 533.6 4.4 3.0 3 1 0 3 3 3 1 Transcription factor Opi1 Perilipin PF03036.11 CCF48226.1 - 0.00033 19.6 0.6 0.0023 16.8 0.0 2.3 1 1 1 2 2 2 1 Perilipin family Big_3_2 PF12245.3 CCF48226.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) REF PF05755.7 CCF48226.1 - 0.15 11.8 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Pkinase PF00069.20 CCF48227.1 - 1.1e-31 109.9 0.0 2.9e-31 108.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48227.1 - 3.7e-14 52.4 0.0 1.5e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF48227.1 - 0.00031 19.8 0.0 0.0027 16.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Hydantoinase_A PF01968.13 CCF48228.1 - 2.5e-89 299.2 0.8 3.6e-89 298.7 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CCF48228.1 - 6.2e-53 178.9 0.0 2.3e-50 170.5 0.0 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region cwf21 PF08312.7 CCF48228.1 - 1.5 8.7 6.4 0.43 10.4 1.6 2.1 2 0 0 2 2 2 0 cwf21 domain MKT1_C PF12246.3 CCF48229.1 - 9.9e-68 227.7 0.0 1.7e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCF48229.1 - 1e-25 89.8 0.0 1.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CCF48229.1 - 1.7e-05 24.7 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCF48229.1 - 4.4e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain zf-C3HC4_3 PF13920.1 CCF48231.1 - 2.8e-10 39.7 3.8 4.2e-10 39.1 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF48231.1 - 1e-05 25.4 2.9 2.1e-05 24.4 2.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF48231.1 - 1.1e-05 24.9 3.4 1.9e-05 24.2 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF48231.1 - 5.5e-05 22.9 5.7 9.3e-05 22.1 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCF48231.1 - 0.00039 20.0 3.4 0.00069 19.2 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain DUF455 PF04305.9 CCF48232.1 - 3.2e-101 337.8 0.0 4.9e-101 337.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 CCF48232.1 - 1.6e-07 30.7 0.2 3.2e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain VPS9 PF02204.13 CCF48233.1 - 1.8e-14 53.6 0.0 3.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain GATA PF00320.22 CCF48234.1 - 0.1 11.9 2.7 1.6 8.1 0.1 2.9 2 0 0 2 2 2 0 GATA zinc finger MFS_1 PF07690.11 CCF48235.1 - 1.8e-19 69.7 45.2 9.9e-17 60.6 11.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily SDA1 PF05285.7 CCF48235.1 - 7.2 5.7 5.0 11 5.2 3.5 1.1 1 0 0 1 1 1 0 SDA1 MFS_1 PF07690.11 CCF48237.1 - 3.8e-36 124.5 30.4 3.8e-36 124.5 21.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PsbM PF05151.7 CCF48237.1 - 4.8 6.8 7.6 7.2 6.3 0.1 2.9 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) F-box-like PF12937.2 CCF48238.1 - 0.00069 19.2 0.1 0.0024 17.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 CCF48238.1 - 0.0032 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 CCF48238.1 - 0.0038 16.8 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Complex1_LYR_1 PF13232.1 CCF48238.1 - 0.028 14.6 0.1 0.088 13.0 0.1 1.8 1 0 0 1 1 1 0 Complex1_LYR-like EF-hand_1 PF00036.27 CCF48239.1 - 4.3e-41 135.1 13.3 5.6e-10 37.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCF48239.1 - 6.5e-37 125.5 4.0 1.9e-20 72.7 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCF48239.1 - 4e-32 109.6 12.4 3.1e-16 58.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CCF48239.1 - 2e-30 101.9 8.1 1.2e-09 37.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCF48239.1 - 3.6e-27 92.4 8.6 7.9e-07 28.1 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CCF48239.1 - 1.8e-13 50.2 0.1 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCF48239.1 - 4.2e-10 39.2 1.3 5.4e-05 22.8 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCF48239.1 - 6.7e-09 35.7 0.0 0.00049 20.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CCF48239.1 - 1.9e-07 30.5 0.0 0.013 15.0 0.0 3.4 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CCF48239.1 - 2.8e-05 24.0 1.2 0.00019 21.3 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 CCF48239.1 - 0.00092 18.8 0.1 0.11 12.0 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein DUF1103 PF06513.6 CCF48239.1 - 0.001 18.5 1.2 0.0012 18.3 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_like PF09279.6 CCF48239.1 - 0.011 15.7 0.5 0.065 13.2 0.1 2.3 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 CCF48239.1 - 0.013 15.2 0.1 1.1 8.9 0.0 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB Poly_export PF02563.11 CCF48239.1 - 0.019 14.7 0.1 3.6 7.4 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CCF48239.1 - 0.021 14.3 0.1 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SapB_1 PF05184.10 CCF48239.1 - 0.032 14.0 0.4 33 4.4 0.0 3.6 4 0 0 4 4 4 0 Saposin-like type B, region 1 Tenui_NCP PF04876.7 CCF48239.1 - 0.057 12.9 0.1 0.73 9.3 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein MotA_activ PF09114.5 CCF48239.1 - 0.088 12.5 0.2 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain RloB PF13707.1 CCF48239.1 - 6 6.4 5.8 46 3.5 4.0 2.4 1 1 0 1 1 1 0 RloB-like protein Mito_carr PF00153.22 CCF48240.1 - 2.3e-64 213.1 2.8 2.5e-21 75.1 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 CCF48241.1 - 1.3e-36 123.1 1.1 4e-07 29.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCF48241.1 - 1.6e-05 24.6 1.2 0.00053 19.7 0.2 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A HPP PF04982.8 CCF48242.1 - 8.6e-33 112.7 6.2 1.5e-32 111.9 4.3 1.4 1 0 0 1 1 1 1 HPP family Glycos_transf_4 PF00953.16 CCF48242.1 - 0.011 15.5 0.2 0.011 15.5 0.2 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 4 Fis1_TPR_C PF14853.1 CCF48243.1 - 3.5e-24 84.4 0.7 5.6e-24 83.7 0.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CCF48243.1 - 1.3e-15 56.3 0.0 2.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 CCF48243.1 - 0.00035 20.2 0.2 0.00098 18.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCF48243.1 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48243.1 - 0.075 13.3 1.6 0.093 13.0 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF48243.1 - 0.086 13.3 0.7 0.29 11.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PX PF00787.19 CCF48244.1 - 1.8e-21 76.0 0.2 4.7e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CCF48244.1 - 6.7e-11 41.9 4.5 3.7e-07 29.6 1.2 2.3 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 CCF48244.1 - 0.0036 16.8 0.2 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 BAR domain MerR-DNA-bind PF09278.6 CCF48244.1 - 0.018 15.4 1.3 1.4 9.4 0.0 3.5 3 0 0 3 3 3 0 MerR, DNA binding DUF1513 PF07433.6 CCF48244.1 - 0.055 12.3 0.2 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Clathrin PF00637.15 CCF48245.1 - 1.2e-206 676.6 36.9 1.2e-32 112.4 0.1 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 CCF48245.1 - 5.4e-34 114.1 4.2 7.7e-06 25.8 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 CCF48245.1 - 1.6e-31 107.9 0.1 6.1e-31 106.1 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 CCF48245.1 - 1.1e-10 40.3 0.2 1.1e-10 40.3 0.1 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_14 PF13428.1 CCF48245.1 - 0.00042 20.7 13.0 8.9 7.2 0.2 9.2 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCF48245.1 - 0.0053 16.6 18.6 0.44 10.5 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCF48245.1 - 0.0089 15.6 7.6 10 5.9 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCF48245.1 - 0.018 14.8 11.0 2.5 8.2 0.1 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF48245.1 - 7.4 6.6 13.0 32 4.6 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.24 CCF48246.1 - 3.5e-43 146.9 0.0 5.9e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF48246.1 - 2.6e-07 30.7 0.1 1.2e-05 25.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CCF48246.1 - 6.3e-07 29.4 0.0 4.5e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCF48246.1 - 7.6e-07 28.9 0.1 1.7e-05 24.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCF48246.1 - 2.7e-06 27.5 0.0 0.001 19.1 0.0 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CCF48246.1 - 8.2e-06 25.0 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCF48246.1 - 0.00019 21.0 0.1 0.00046 19.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CCF48246.1 - 0.00065 18.6 0.0 0.0018 17.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCF48246.1 - 0.00078 20.2 0.9 0.0025 18.6 0.2 2.4 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CCF48246.1 - 0.0013 18.6 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCF48246.1 - 0.0025 17.0 0.0 0.0051 15.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCF48246.1 - 0.0026 16.5 0.0 0.005 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CCF48246.1 - 0.003 17.4 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCF48246.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CCF48246.1 - 0.005 16.9 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CCF48246.1 - 0.0052 17.0 1.4 0.017 15.3 0.0 2.5 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.1 CCF48246.1 - 0.0056 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CCF48246.1 - 0.0079 15.6 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain ResIII PF04851.10 CCF48246.1 - 0.0086 15.9 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 CCF48246.1 - 0.0098 15.0 0.1 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCF48246.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCF48246.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 CCF48246.1 - 0.018 14.9 2.1 0.046 13.6 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_25 PF13481.1 CCF48246.1 - 0.024 14.0 0.2 0.12 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCF48246.1 - 0.025 14.2 0.6 0.17 11.5 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase NACHT PF05729.7 CCF48246.1 - 0.031 13.9 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 CCF48246.1 - 0.032 13.4 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CCF48246.1 - 0.032 13.3 0.1 0.15 11.1 0.0 2.0 1 1 0 2 2 2 0 KaiC AAA_30 PF13604.1 CCF48246.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCF48246.1 - 0.036 14.1 0.1 0.13 12.2 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain DASH_Dad3 PF08656.5 CCF48246.1 - 0.039 13.6 0.5 0.09 12.4 0.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 UPF0079 PF02367.12 CCF48246.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CCF48246.1 - 0.066 12.7 0.3 0.5 9.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 CCF48246.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 CCF48246.1 - 0.069 13.4 4.3 8.9 6.5 1.4 2.4 2 1 0 2 2 2 0 AAA domain CPT PF07931.7 CCF48246.1 - 0.087 12.4 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_1 PF00515.23 CCF48246.1 - 6 6.6 6.4 0.54 9.9 0.6 2.2 3 0 0 3 3 2 0 Tetratricopeptide repeat GPI-anchored PF10342.4 CCF48247.1 - 5.1e-08 33.2 0.2 8.4e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 CCF48247.1 - 0.032 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CBM_5_12 PF02839.9 CCF48247.1 - 0.071 12.6 1.8 0.15 11.6 1.2 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain DUF3035 PF11233.3 CCF48248.1 - 0.95 9.4 4.6 1.2 9.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF605 PF04652.11 CCF48249.1 - 0.17 11.2 15.7 0.23 10.8 10.9 1.1 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 CCF48250.1 - 3.4e-05 23.6 7.5 6.4e-05 22.7 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_10 PF05971.7 CCF48251.1 - 2.4e-48 164.8 0.0 4.1e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 CCF48251.1 - 0.0018 18.7 0.0 0.027 14.9 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF48251.1 - 0.0029 18.1 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CENP-O PF09496.5 CCF48252.1 - 1.5e-22 79.5 0.0 3.5e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Pkinase PF00069.20 CCF48254.1 - 7.6e-68 228.4 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48254.1 - 3.8e-34 117.9 0.0 6.6e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF48254.1 - 0.0027 17.4 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCF48254.1 - 0.0095 15.5 0.2 0.035 13.6 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CCF48254.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCF48254.1 - 0.017 14.0 0.0 0.039 12.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CCF48254.1 - 0.057 12.7 0.0 0.15 11.3 0.0 1.7 1 1 0 1 1 1 0 RIO1 family EAL PF00563.15 CCF48254.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 EAL domain Histone PF00125.19 CCF48255.1 - 9e-31 105.8 0.4 1.4e-30 105.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCF48255.1 - 5.5e-06 26.4 0.0 8.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCF48255.1 - 0.0018 18.3 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCF48255.1 - 0.0036 16.9 0.1 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 CCF48255.1 - 0.14 11.3 1.0 0.22 10.7 0.7 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2296 PF10058.4 CCF48256.1 - 8e-21 73.5 0.2 1.4e-20 72.8 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) UcrQ PF02939.11 CCF48257.1 - 1.2e-23 82.6 1.9 1.6e-23 82.3 1.3 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 CCF48257.1 - 0.12 12.5 0.3 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2741) CNH PF00780.17 CCF48258.1 - 9.8e-85 284.2 0.0 1.5e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 CCF48258.1 - 6.9e-50 168.4 0.6 1.2e-49 167.7 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 CCF48258.1 - 2.7e-38 131.6 0.2 2.7e-38 131.6 0.1 1.6 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 CCF48258.1 - 5.6e-13 48.4 0.0 1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HIG_1_N PF04588.8 CCF48259.1 - 7.2e-06 25.6 1.7 1.3e-05 24.8 1.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1115 PF06544.7 CCF48260.1 - 0.0015 18.2 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1115) ETC_C1_NDUFA5 PF04716.9 CCF48261.1 - 3.8e-15 55.1 3.2 8.6e-15 54.0 1.5 2.2 2 1 0 2 2 2 1 ETC complex I subunit conserved region PspA_IM30 PF04012.7 CCF48261.1 - 0.033 13.5 8.4 0.045 13.0 5.8 1.2 1 0 0 1 1 1 0 PspA/IM30 family T2SM PF04612.7 CCF48261.1 - 0.038 13.7 7.9 0.033 13.9 3.7 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M OEP PF02321.13 CCF48261.1 - 0.11 12.0 8.3 0.16 11.5 5.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein T5orf172 PF10544.4 CCF48261.1 - 0.14 12.6 0.1 0.56 10.6 0.0 1.9 2 0 0 2 2 2 0 T5orf172 domain ATP-synt_B PF00430.13 CCF48261.1 - 0.19 11.5 6.7 0.25 11.1 4.6 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Smoothelin PF12510.3 CCF48261.1 - 0.64 9.9 3.1 2.2 8.2 2.2 1.9 1 1 0 1 1 1 0 Smoothelin cytoskeleton protein WW PF00397.21 CCF48262.1 - 0.0027 17.5 1.4 0.0064 16.3 1.0 1.6 1 0 0 1 1 1 1 WW domain Sel1 PF08238.7 CCF48263.1 - 1e-41 140.3 29.2 4.9e-07 30.1 1.0 9.3 9 0 0 9 9 9 7 Sel1 repeat DAO PF01266.19 CCF48264.1 - 1.3e-46 159.1 0.0 2.4e-46 158.3 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCF48264.1 - 1.2e-08 34.2 0.7 8.5e-06 24.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CCF48264.1 - 2.9e-07 30.5 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCF48264.1 - 3.2e-07 29.5 0.0 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CCF48264.1 - 1.1e-06 28.8 0.0 0.004 17.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF48264.1 - 3.4e-06 26.9 0.1 0.018 14.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCF48264.1 - 4.2e-06 27.0 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF48264.1 - 2.6e-05 24.1 0.0 6.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCF48264.1 - 4e-05 22.2 0.0 0.0091 14.5 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.13 CCF48264.1 - 0.00062 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CCF48264.1 - 0.002 17.2 0.0 0.032 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCF48264.1 - 0.0022 17.1 0.0 0.005 15.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 CCF48264.1 - 0.0023 16.6 0.0 0.019 13.6 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 CCF48264.1 - 0.0035 16.3 0.1 0.027 13.4 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 CCF48264.1 - 0.0078 15.3 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF48264.1 - 0.024 14.6 0.1 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 CCF48264.1 - 0.033 13.7 0.0 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 CCF48264.1 - 0.038 13.0 0.0 0.16 11.0 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase XdhC_C PF13478.1 CCF48264.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 1 0 XdhC Rossmann domain ApbA PF02558.11 CCF48264.1 - 0.075 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CCF48264.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HA2 PF04408.18 CCF48265.1 - 2.7e-28 97.9 1.9 3e-28 97.8 0.1 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCF48265.1 - 3.2e-28 97.8 0.0 7e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCF48265.1 - 6.2e-13 48.4 0.0 1.6e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 CCF48265.1 - 6.6e-08 32.5 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CCF48265.1 - 4e-05 23.1 0.1 4e-05 23.1 0.1 1.7 2 0 0 2 2 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF48265.1 - 0.00023 21.3 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCF48265.1 - 0.00025 20.0 0.2 0.00077 18.4 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 CCF48265.1 - 0.0044 17.3 0.2 0.83 9.9 0.1 3.3 2 1 0 2 2 2 1 ABC transporter AAA_19 PF13245.1 CCF48265.1 - 0.02 14.6 0.2 0.062 13.0 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 CCF48265.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 CCF48265.1 - 0.077 12.8 0.0 0.46 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CCF48265.1 - 0.081 12.1 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 CCF48265.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 CCF48265.1 - 0.17 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DAGAT PF03982.8 CCF48266.1 - 2.2e-105 351.5 0.0 2.8e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 CCF48266.1 - 0.09 12.3 0.5 0.17 11.4 0.4 1.5 1 0 0 1 1 1 0 Rer1 family CS PF04969.11 CCF48267.1 - 9e-06 26.1 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 CCF48267.1 - 5.3 7.4 18.5 9.1 6.6 12.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region RRM_1 PF00076.17 CCF48268.1 - 4.6e-16 58.1 0.0 1.6e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48268.1 - 2.8e-13 49.6 0.0 9.6e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48268.1 - 3.6e-10 39.5 0.0 1.1e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 CCF48268.1 - 0.29 9.0 15.8 0.016 13.3 6.9 1.8 2 0 0 2 2 2 0 CDC45-like protein Spore_coat_CotO PF14153.1 CCF48268.1 - 0.35 10.2 14.4 0.029 13.8 5.5 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Limkain-b1 PF11608.3 CCF48268.1 - 0.68 9.7 7.0 5.6 6.7 0.0 3.5 4 0 0 4 4 4 0 Limkain b1 DUF2782 PF11191.3 CCF48268.1 - 2.3 8.2 10.1 2.1 8.3 0.1 3.6 2 2 0 2 2 2 0 Protein of unknown function (DUF2782) SIT PF15330.1 CCF48268.1 - 7.3 6.7 6.2 20 5.3 4.3 1.8 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT NUDIX PF00293.23 CCF48269.1 - 5.5e-12 45.4 0.0 8.1e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3218 PF11508.3 CCF48269.1 - 0.0058 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3218) FAD_binding_3 PF01494.14 CCF48269.1 - 0.11 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pro_isomerase PF00160.16 CCF48270.1 - 4.8e-35 121.0 0.0 1.1e-34 119.8 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 CCF48270.1 - 0.028 14.6 5.2 0.028 14.6 3.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) Glyco_hydro_63 PF03200.11 CCF48271.1 - 5.1e-06 24.6 0.2 5.1e-06 24.6 0.1 3.8 5 1 0 5 5 5 2 Mannosyl oligosaccharide glucosidase Methyltransf_16 PF10294.4 CCF48272.1 - 2.6e-18 66.0 0.0 1.5e-08 34.3 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase RrnaAD PF00398.15 CCF48272.1 - 7.5e-05 21.8 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CCF48272.1 - 0.0002 21.9 0.0 0.00037 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF48272.1 - 0.028 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3643 PF12356.3 CCF48272.1 - 0.043 13.1 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) Methyltransf_26 PF13659.1 CCF48272.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.10 CCF48272.1 - 0.058 12.8 0.0 1.2 8.5 0.0 2.3 1 1 1 2 2 2 0 NADPH-dependent FMN reductase MTS PF05175.9 CCF48272.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PH PF00169.24 CCF48273.1 - 5.2e-05 23.3 0.0 0.088 13.0 0.0 3.0 3 0 0 3 3 3 2 PH domain BSP_II PF05432.6 CCF48273.1 - 0.0022 17.3 2.6 0.0062 15.8 1.8 1.8 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) PH_9 PF15410.1 CCF48273.1 - 0.05 13.7 0.1 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Nucleoplasmin PF03066.10 CCF48273.1 - 0.079 12.4 4.3 0.15 11.5 3.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCF48273.1 - 0.93 8.6 1.7 1.5 7.9 1.2 1.2 1 0 0 1 1 1 0 NOA36 protein VHS PF00790.14 CCF48274.1 - 2.6e-32 111.3 1.1 2.9e-32 111.2 0.1 1.5 2 0 0 2 2 2 1 VHS domain SH3_9 PF14604.1 CCF48274.1 - 2.8e-15 55.5 0.1 5.5e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCF48274.1 - 3.1e-15 55.2 0.0 5.6e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCF48274.1 - 1.9e-12 46.4 0.1 3.1e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 CCF48274.1 - 0.00038 20.3 0.1 0.0013 18.6 0.1 2.0 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 CCF48274.1 - 0.012 15.1 2.0 0.012 15.1 1.4 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Hrs_helical PF12210.3 CCF48274.1 - 0.014 15.6 0.4 0.038 14.2 0.3 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Cyt-b5 PF00173.23 CCF48275.1 - 2.3e-18 65.7 0.0 3.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain A_deaminase PF00962.17 CCF48277.1 - 1.1e-109 366.3 0.2 1.5e-109 365.9 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Rep_fac_C PF08542.6 CCF48278.1 - 6.5e-20 70.9 0.0 1.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CCF48278.1 - 1.1e-16 61.1 0.0 2.3e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCF48278.1 - 2e-16 60.0 0.0 2.7e-14 53.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CCF48278.1 - 1.4e-12 47.0 0.0 1.7e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCF48278.1 - 8.1e-06 26.0 0.1 0.0037 17.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCF48278.1 - 1e-05 24.6 0.0 7.2e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCF48278.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 CCF48278.1 - 7.7e-05 22.3 0.0 0.00018 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCF48278.1 - 8.2e-05 22.6 0.0 0.0025 17.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCF48278.1 - 0.0002 21.0 0.0 0.00047 19.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 CCF48278.1 - 0.00024 20.6 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.1 CCF48278.1 - 0.00053 19.6 0.0 0.00095 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCF48278.1 - 0.00073 19.2 0.1 0.0041 16.8 0.0 2.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CCF48278.1 - 0.00084 18.3 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 CCF48278.1 - 0.0033 16.9 0.1 2.9 7.2 0.0 2.5 1 1 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 CCF48278.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CCF48278.1 - 0.016 14.7 0.1 0.17 11.3 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 CCF48278.1 - 0.021 14.6 0.0 0.11 12.3 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CCF48278.1 - 0.024 13.7 0.0 0.14 11.3 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CCF48278.1 - 0.034 13.7 0.4 0.26 10.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 CCF48278.1 - 0.039 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 CCF48278.1 - 0.05 13.2 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCF48278.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 CCF48278.1 - 0.082 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 CCF48278.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Nucleopor_Nup85 PF07575.8 CCF48279.1 - 1.9e-86 290.5 0.0 9.4e-52 175.9 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin zf-C2H2_jaz PF12171.3 CCF48280.1 - 4.1e-09 36.3 1.5 7.3e-09 35.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF48280.1 - 0.00057 19.9 1.0 0.00097 19.2 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCF48280.1 - 0.0009 19.3 0.4 0.0009 19.3 0.3 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCF48280.1 - 0.021 15.1 1.7 0.021 15.1 1.2 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3020 PF11223.3 CCF48280.1 - 0.044 14.1 0.1 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) Phlebovirus_NSM PF07246.6 CCF48280.1 - 0.13 11.4 0.4 0.16 11.0 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AKAP95 PF04988.7 CCF48280.1 - 0.18 11.5 1.8 0.37 10.5 1.3 1.7 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Ribosomal_L35Ae PF01247.13 CCF48281.1 - 4.7e-42 141.6 1.8 5.2e-42 141.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCF48281.1 - 0.0035 17.2 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF1746 PF08508.5 CCF48282.1 - 2.1e-20 72.7 7.7 3e-20 72.2 5.3 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Scm3 PF10384.4 CCF48283.1 - 6.2e-22 76.8 0.3 2.2e-19 68.7 0.2 2.6 2 0 0 2 2 2 2 Centromere protein Scm3 dsrm PF00035.20 CCF48284.1 - 2.9e-07 30.9 0.0 6.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Telethonin PF09470.5 CCF48284.1 - 0.036 13.5 0.0 0.083 12.3 0.0 1.5 1 1 0 1 1 1 0 Telethonin protein ACC_central PF08326.7 CCF48285.1 - 6.4e-213 708.8 0.1 9.5e-213 708.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCF48285.1 - 1.1e-169 564.9 0.0 1.4e-169 564.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCF48285.1 - 3.4e-53 180.0 0.0 6.5e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCF48285.1 - 2.3e-23 82.3 0.0 6.4e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCF48285.1 - 2.3e-21 75.7 0.1 8.4e-20 70.7 0.0 3.0 3 0 0 3 3 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCF48285.1 - 4.5e-14 51.8 0.2 9.6e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCF48285.1 - 5.5e-14 52.3 0.0 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCF48285.1 - 4.9e-07 29.3 0.1 2.2e-06 27.2 0.0 2.2 2 0 0 2 2 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 CCF48285.1 - 8.4e-05 21.9 0.0 0.00021 20.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCF48285.1 - 0.001 18.5 0.0 0.012 15.1 0.0 2.4 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCF48285.1 - 0.0048 16.3 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCF48285.1 - 0.0083 16.0 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 CCF48285.1 - 0.012 15.3 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_2 PF12700.2 CCF48285.1 - 0.035 13.2 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein HlyD PF00529.15 CCF48285.1 - 0.054 12.7 0.0 0.054 12.7 0.0 3.4 3 1 0 3 3 2 0 HlyD family secretion protein PapC_C PF13953.1 CCF48285.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain ERCC4 PF02732.10 CCF48286.1 - 3.3e-24 85.2 0.0 7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 CCF48286.1 - 1.8e-08 34.4 0.1 2.7e-07 30.6 0.0 2.6 2 1 1 3 3 3 1 Helix-hairpin-helix domain Cytochrom_C1 PF02167.10 CCF48287.1 - 2.2e-85 285.7 0.0 2.7e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCF48287.1 - 0.00042 20.4 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CCF48287.1 - 0.025 15.3 0.2 0.094 13.5 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c Ribosomal_60s PF00428.14 CCF48288.1 - 7e-28 96.8 11.7 9.2e-28 96.4 8.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 CCF48290.1 - 1.6e-30 104.4 0.2 2.3e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_L18p PF00861.17 CCF48291.1 - 9.8e-41 138.6 0.2 4e-40 136.7 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCF48291.1 - 6.2e-33 113.2 1.4 1.6e-32 111.9 0.9 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L15e PF00827.12 CCF48292.1 - 1.2e-89 298.8 13.2 1.4e-89 298.6 9.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 TPP1 PF10341.4 CCF48293.1 - 4e-08 33.2 0.0 1.2e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD NESP55 PF06390.7 CCF48293.1 - 0.082 12.2 10.3 0.54 9.5 2.0 2.2 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 CCF48293.1 - 0.98 9.2 11.6 2.2 8.0 8.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DER1 PF04511.10 CCF48294.1 - 0.00024 20.6 1.1 0.00036 20.0 0.8 1.3 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CCF48294.1 - 0.0017 18.3 0.9 0.0017 18.3 0.6 2.3 3 0 0 3 3 3 1 Rhomboid family DUF1751 PF08551.5 CCF48294.1 - 0.19 12.0 4.2 0.13 12.6 0.6 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) EAP30 PF04157.11 CCF48295.1 - 1.9e-46 157.9 0.1 3.1e-46 157.3 0.1 1.3 1 1 0 1 1 1 1 EAP30/Vps36 family BID PF06393.6 CCF48295.1 - 0.03 13.6 0.2 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 BH3 interacting domain (BID) TB2_DP1_HVA22 PF03134.14 CCF48296.1 - 7e-28 96.2 9.6 1.2e-27 95.5 6.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.13 CCF48297.1 - 7.4e-07 28.9 6.1 0.00099 18.9 0.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.21 CCF48298.1 - 8.4e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF48298.1 - 0.00031 20.3 0.2 0.0016 18.0 0.1 2.3 1 1 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CCF48298.1 - 0.022 14.2 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Glyco_hydro_11 PF00457.12 CCF48300.1 - 8.6e-53 178.4 16.5 1e-52 178.1 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Uroplakin_II PF07353.7 CCF48300.1 - 0.058 12.7 0.4 0.089 12.1 0.3 1.2 1 0 0 1 1 1 0 Uroplakin II Foie-gras_1 PF11817.3 CCF48301.1 - 3.9e-32 111.6 0.0 1.4e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.7 CCF48301.1 - 4.1e-15 55.1 3.3 1.6e-14 53.1 2.3 1.8 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi PRCC PF10253.4 CCF48302.1 - 7.4e-06 26.7 9.1 7.4e-06 26.7 6.3 5.1 2 2 2 4 4 4 1 Mitotic checkpoint regulator, MAD2B-interacting Lsm_interact PF05391.6 CCF48302.1 - 0.12 11.8 3.3 0.13 11.7 0.1 2.9 2 0 0 2 2 2 0 Lsm interaction motif TMEM190 PF15431.1 CCF48302.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 190 Peptidase_S10 PF00450.17 CCF48303.1 - 2.3e-105 353.1 0.0 2.9e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCF48303.1 - 0.00015 21.6 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Varsurf_PPLC PF03490.8 CCF48303.1 - 0.041 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Variant-surface-glycoprotein phospholipase C Candida_ALS PF05792.8 CCF48305.1 - 6.2 7.0 19.0 1.5 9.0 9.4 2.8 2 0 0 2 2 2 0 Candida agglutinin-like (ALS) YL1_C PF08265.6 CCF48306.1 - 1.7e-15 56.2 0.3 1.7e-15 56.2 0.2 1.6 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Gag_p30 PF02093.11 CCF48306.1 - 0.015 14.5 0.3 0.025 13.7 0.2 1.3 1 0 0 1 1 1 0 Gag P30 core shell protein Spore_coat_CotO PF14153.1 CCF48306.1 - 1.6 8.1 11.2 2.7 7.3 7.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 CCF48306.1 - 9.9 4.7 16.2 12 4.4 11.2 1.0 1 0 0 1 1 1 0 Paf1 DNA_pol3_gamma3 PF12169.3 CCF48308.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Adeno_E3_CR2 PF02439.10 CCF48309.1 - 0.23 11.0 0.1 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Prefoldin_2 PF01920.15 CCF48310.1 - 3.2e-24 84.7 7.7 4.5e-24 84.2 5.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit CAP_assoc_N PF14504.1 CCF48310.1 - 0.01 15.5 0.3 0.025 14.2 0.1 1.6 1 1 1 2 2 2 0 CAP-associated N-terminal DUF4600 PF15372.1 CCF48310.1 - 0.012 15.8 3.6 0.018 15.2 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Sec3_C PF09763.4 CCF48310.1 - 0.013 13.6 0.6 0.013 13.6 0.4 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec3 Prefoldin PF02996.12 CCF48310.1 - 0.088 12.4 6.0 0.13 11.9 2.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit LRS4 PF10422.4 CCF48310.1 - 0.11 11.8 3.0 0.13 11.5 2.1 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ADIP PF11559.3 CCF48310.1 - 0.16 11.8 3.1 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PspA_IM30 PF04012.7 CCF48310.1 - 0.17 11.2 5.8 0.086 12.1 1.2 1.9 2 0 0 2 2 2 0 PspA/IM30 family ALIX_LYPXL_bnd PF13949.1 CCF48310.1 - 0.19 10.6 8.1 1.3 7.9 0.6 2.0 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF724 PF05266.9 CCF48310.1 - 0.29 10.7 6.7 0.31 10.6 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF342 PF03961.8 CCF48310.1 - 0.36 9.1 3.9 0.45 8.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CCF48310.1 - 0.44 10.8 4.0 0.51 10.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YlqD PF11068.3 CCF48310.1 - 0.5 10.4 6.5 4.4 7.3 0.7 2.1 1 1 1 2 2 2 0 YlqD protein Seryl_tRNA_N PF02403.17 CCF48310.1 - 0.71 9.9 6.5 0.13 12.2 0.7 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3847 PF12958.2 CCF48310.1 - 0.75 9.6 4.9 0.85 9.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TMF_DNA_bd PF12329.3 CCF48310.1 - 1.1 9.1 9.7 0.32 10.8 2.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Nsp1_C PF05064.8 CCF48310.1 - 1.2 8.7 8.8 0.12 12.0 1.1 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0122 PF04297.9 CCF48310.1 - 1.3 9.0 5.4 1.9 8.5 0.4 2.3 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like FTA4 PF13093.1 CCF48310.1 - 1.6 8.1 6.6 5.1 6.4 4.7 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CCDC-167 PF15188.1 CCF48310.1 - 1.6 8.7 9.1 13 5.7 6.3 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF515 PF04415.7 CCF48310.1 - 2.1 6.5 5.5 2.5 6.2 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TBPIP PF07106.8 CCF48310.1 - 4.1 6.9 8.0 0.5 9.8 0.7 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CCF48310.1 - 4.2 6.9 11.9 17 4.9 8.3 1.8 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 CCF48310.1 - 6 6.9 10.0 1.1 9.3 1.7 2.1 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.16 CCF48310.1 - 6.8 6.7 7.9 1.4 8.9 1.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor Glyco_trans_1_4 PF13692.1 CCF48311.1 - 4.8e-15 55.9 0.0 5.7e-13 49.1 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCF48311.1 - 1.9e-10 41.0 4.0 2.4e-10 40.8 1.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CCF48311.1 - 0.00065 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CCF48311.1 - 0.044 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Exo_endo_phos_2 PF14529.1 CCF48314.1 - 0.075 12.6 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase rve PF00665.21 CCF48315.1 - 5.6e-21 74.8 0.0 1.5e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF48315.1 - 0.0081 15.6 2.7 0.017 14.5 0.2 2.4 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 CCF48316.1 - 0.00011 21.9 1.3 0.00029 20.6 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CCF48316.1 - 0.0023 17.9 0.1 0.0064 16.5 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein eIF3g PF12353.3 CCF48316.1 - 0.036 13.9 0.3 0.07 13.0 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 CCF48316.1 - 0.046 13.2 2.6 0.067 12.6 0.4 2.2 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.1 CCF48316.1 - 0.048 13.1 2.2 0.094 12.2 1.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF1992 PF09350.5 CCF48317.1 - 4.5e-19 68.0 0.3 2.6e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Dynein_light PF01221.13 CCF48318.1 - 4.7e-38 129.0 0.3 5.5e-38 128.8 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Suc_Fer-like PF06999.7 CCF48320.1 - 9.6e-24 84.6 0.0 1.8e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Radical_SAM PF04055.16 CCF48320.1 - 1.1e-10 41.8 0.0 1.9e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.6 CCF48320.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal LRR_9 PF14580.1 CCF48322.1 - 2.5e-52 176.9 0.1 3.4e-52 176.5 0.1 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCF48322.1 - 1.4e-14 53.3 26.6 1.4e-07 30.9 1.3 3.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF48322.1 - 1.4e-10 40.7 8.7 2.9e-09 36.5 4.6 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CCF48322.1 - 4e-06 26.3 7.2 1.1 9.4 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 CCF48322.1 - 0.2 11.8 14.7 2.4 8.5 0.4 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CCF48322.1 - 0.22 11.8 5.1 62 4.4 0.3 4.3 4 0 0 4 4 4 0 Leucine rich repeat MFS_1 PF07690.11 CCF48323.1 - 6.1e-18 64.6 41.6 6.1e-18 64.6 28.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CRAL_TRIO_2 PF13716.1 CCF48324.1 - 2.1e-32 112.1 0.0 3.7e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CCF48324.1 - 5.6e-23 81.2 0.0 1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain AAA PF00004.24 CCF48325.1 - 1e-49 168.1 0.0 2.7e-41 140.8 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF48325.1 - 1e-06 28.8 5.5 3.2e-05 23.9 0.0 4.2 4 1 0 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 CCF48325.1 - 4.1e-05 23.0 0.0 9.3e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 CCF48325.1 - 7.6e-05 22.6 0.8 0.00028 20.8 0.0 2.4 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCF48325.1 - 0.00082 19.5 0.1 0.044 13.9 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CCF48325.1 - 0.00086 19.0 0.1 0.01 15.5 0.0 3.0 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCF48325.1 - 0.0016 18.1 0.0 0.0063 16.2 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCF48325.1 - 0.005 16.7 5.4 0.042 13.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCF48325.1 - 0.012 15.8 2.6 0.068 13.4 0.0 3.5 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.1 CCF48325.1 - 0.015 16.0 4.2 0.027 15.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 CCF48325.1 - 0.021 14.2 1.6 0.031 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CCF48325.1 - 0.068 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 CCF48325.1 - 0.087 13.0 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.27 CCF48326.1 - 5.2e-69 225.8 22.1 2e-13 49.6 1.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCF48326.1 - 1.2e-05 24.7 0.0 0.3 10.6 0.0 5.1 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 CCF48326.1 - 0.025 14.2 0.0 6 6.5 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CCF48326.1 - 0.17 9.6 0.6 2.4 5.8 0.0 2.2 2 0 0 2 2 2 0 IKI3 family DUF4136 PF13590.1 CCF48327.1 - 0.083 12.9 0.7 0.095 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) FGGY_N PF00370.16 CCF48328.1 - 2.3e-72 243.2 0.7 3e-72 242.8 0.5 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CCF48328.1 - 2.3e-65 219.9 1.7 5.5e-65 218.7 0.6 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain TFIIS_C PF01096.13 CCF48329.1 - 2.4e-19 68.6 3.5 2.4e-19 68.6 2.4 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCF48329.1 - 5.8e-10 38.6 2.0 5.8e-10 38.6 1.4 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CCF48329.1 - 0.015 15.0 8.3 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 CCF48329.1 - 0.032 14.5 6.6 1 9.7 0.5 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-DNA_Pol PF08996.5 CCF48329.1 - 1.1 8.6 5.1 0.23 10.7 0.1 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger DZR PF12773.2 CCF48329.1 - 1.4 8.8 6.4 3.4 7.5 0.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon Terminase_GpA PF05876.7 CCF48329.1 - 1.4 7.1 4.9 0.37 9.0 0.8 1.7 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 CCF48329.1 - 8.2 5.8 9.2 0.64 9.3 0.4 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding NRDE PF05742.7 CCF48330.1 - 7.4e-43 146.8 0.0 1.5e-41 142.5 0.0 2.4 1 1 0 1 1 1 1 NRDE protein Ribosomal_S19e PF01090.14 CCF48331.1 - 4.9e-55 184.8 0.0 5.7e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SDA1 PF05285.7 CCF48331.1 - 0.079 12.2 9.3 0.093 11.9 6.5 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 CCF48331.1 - 0.47 10.2 5.1 0.6 9.9 3.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 CCF48331.1 - 0.68 9.1 6.4 0.75 9.0 4.4 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CCF48331.1 - 0.84 7.4 9.9 0.85 7.4 6.9 1.0 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 CCF48331.1 - 1.6 7.9 14.5 2 7.6 10.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 CCF48331.1 - 1.9 8.9 9.7 3.6 8.0 6.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.9 CCF48331.1 - 2.2 6.2 7.4 2.5 6.0 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 CCF48331.1 - 7.5 6.9 11.6 12 6.3 8.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 CCF48331.1 - 9.5 5.7 14.5 13 5.3 10.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region AphA_like PF14557.1 CCF48332.1 - 0.0018 17.8 1.2 0.0049 16.4 0.8 1.8 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator FlaC_arch PF05377.6 CCF48332.1 - 4.6 7.2 9.3 16 5.4 0.1 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) HA2 PF04408.18 CCF48333.1 - 5.4e-20 71.3 0.3 8.8e-19 67.4 0.0 3.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF48333.1 - 5.5e-13 48.5 0.1 6.3e-12 45.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCF48333.1 - 6.7e-13 48.4 0.0 3.8e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCF48333.1 - 1.3e-05 24.7 0.1 2.9e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF48333.1 - 3.6e-05 23.9 0.1 0.00016 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCF48333.1 - 0.0015 17.7 0.1 0.005 15.9 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_23 PF13476.1 CCF48333.1 - 0.076 13.3 0.0 0.076 13.3 0.0 4.1 5 0 0 5 5 5 0 AAA domain 4HBT PF03061.17 CCF48334.1 - 4.7e-11 42.6 0.1 8.7e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 CCF48334.1 - 0.054 13.4 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Fim-adh_lectin PF09222.5 CCF48334.1 - 0.067 12.4 0.5 0.092 12.0 0.3 1.2 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain DHDPS PF00701.17 CCF48335.1 - 4.4e-38 130.5 0.0 5.2e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ParA PF10609.4 CCF48336.1 - 1.1e-31 108.4 0.1 1.8e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCF48336.1 - 9.7e-16 57.7 1.5 5.7e-15 55.2 1.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCF48336.1 - 2.3e-08 34.1 0.3 6.5e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 CCF48336.1 - 2.8e-05 23.8 0.1 0.011 15.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.10 CCF48336.1 - 3.7e-05 22.9 1.6 0.00037 19.6 0.4 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 CCF48336.1 - 0.0028 16.7 0.1 0.0075 15.3 0.0 1.7 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.13 CCF48336.1 - 0.004 16.3 0.1 0.041 13.0 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 CCF48336.1 - 0.0072 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF48336.1 - 0.019 15.7 0.1 0.077 13.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_N PF04675.9 CCF48337.1 - 2.2e-37 128.6 0.0 5.1e-37 127.3 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 CCF48337.1 - 1.7e-33 115.6 0.1 1.2e-22 80.2 0.0 4.7 5 0 0 5 5 5 4 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 CCF48337.1 - 1.9e-16 60.2 0.0 5.9e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pkinase PF00069.20 CCF48338.1 - 9.8e-38 129.7 0.0 1.7e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48338.1 - 1.8e-12 46.8 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.5 CCF48338.1 - 2.9e-08 32.4 0.1 1.9e-06 26.4 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.18 CCF48338.1 - 9.5e-06 25.5 0.0 9.5e-06 25.5 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCF48338.1 - 0.0025 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CCF48338.1 - 0.17 10.9 0.0 0.46 9.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase_phd PF10503.4 CCF48339.1 - 4.4e-13 48.9 0.3 1.4e-12 47.3 0.2 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 CCF48339.1 - 2.4e-09 36.7 0.9 3.6e-09 36.1 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCF48339.1 - 5.7e-08 32.6 0.1 7.9e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF48339.1 - 4.1e-05 23.5 0.0 9.7e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF48339.1 - 0.0024 17.4 0.3 0.005 16.4 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 CCF48339.1 - 0.11 11.5 0.2 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_6 PF13344.1 CCF48341.1 - 1.6e-22 79.3 0.0 3e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF48341.1 - 1.9e-19 69.1 0.0 4.9e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CCF48341.1 - 0.019 15.2 0.1 1 9.5 0.0 3.0 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF48341.1 - 0.14 12.5 0.0 1.4 9.2 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF829 PF05705.9 CCF48342.1 - 3.7e-24 85.7 0.0 1.8e-17 63.8 0.0 3.4 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Transglut_core3 PF13471.1 CCF48342.1 - 0.018 14.8 0.1 0.076 12.8 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Host_attach PF10116.4 CCF48342.1 - 1.6 8.9 6.2 0.3 11.3 0.1 2.8 3 0 0 3 3 3 0 Protein required for attachment to host cells MFS_1 PF07690.11 CCF48343.1 - 8.5e-24 83.9 47.7 8.5e-24 83.9 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 CCF48344.1 - 4.5e-32 109.5 0.0 5e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48344.1 - 6.6e-18 64.4 0.0 9.2e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48344.1 - 7.4e-18 64.1 0.0 8.6e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF48344.1 - 0.00058 19.5 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.6 CCF48344.1 - 0.014 14.9 0.2 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Rab5ip PF07019.7 CCF48345.1 - 4.1e-10 39.6 3.9 4.6e-08 33.0 0.2 2.2 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) Shugoshin_C PF07557.6 CCF48346.1 - 1.8e-08 33.7 2.0 1.8e-08 33.7 1.4 3.3 4 0 0 4 4 4 1 Shugoshin C terminus Shugoshin_N PF07558.6 CCF48346.1 - 6.3e-05 22.6 1.8 0.00012 21.6 1.3 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Actin PF00022.14 CCF48347.1 - 6.7e-34 116.9 0.0 6.1e-33 113.8 0.0 2.3 1 1 0 1 1 1 1 Actin Band_7 PF01145.20 CCF48348.1 - 1.7e-21 76.9 0.4 2.8e-21 76.2 0.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ribosomal_L1 PF00687.16 CCF48349.1 - 1.6e-52 178.0 3.8 1.8e-52 177.8 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CN_hydrolase PF00795.17 CCF48350.1 - 3.2e-24 85.3 0.0 4.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 CCF48351.1 - 1.6e-39 135.6 46.7 8.3e-28 97.1 14.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CCF48352.1 - 1.2e-18 66.9 26.3 1.2e-18 66.9 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF48352.1 - 0.0011 17.5 5.3 0.0011 17.5 3.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter AA_permease PF00324.16 CCF48353.1 - 4.1e-112 374.9 46.0 5e-112 374.6 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF48353.1 - 7.4e-30 103.8 50.2 9.4e-30 103.4 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 CCF48354.1 - 3.9e-18 65.4 0.0 2e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48354.1 - 4.1e-15 55.4 0.3 2.8e-13 49.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF48354.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AMP-binding PF00501.23 CCF48355.1 - 0 1313.4 3.3 1.5e-77 260.7 0.0 6.3 6 0 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 CCF48355.1 - 1.1e-153 510.4 13.2 1.1e-34 119.6 0.2 5.4 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 CCF48355.1 - 6.6e-69 228.1 7.5 1.8e-15 56.9 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site NRPS PF08415.5 CCF48355.1 - 2.4e-39 132.8 2.9 1.6e-09 37.3 0.0 4.9 4 0 0 4 4 4 4 Nonribosomal peptide synthase AMP-binding_C PF13193.1 CCF48355.1 - 3.3e-32 111.2 10.5 4.1e-08 34.0 0.1 7.8 8 0 0 8 8 8 4 AMP-binding enzyme C-terminal domain Nitroreductase PF00881.19 CCF48355.1 - 0.017 14.9 0.0 11 5.8 0.0 3.7 3 0 0 3 3 3 0 Nitroreductase family BEX PF04538.7 CCF48355.1 - 8.3 6.6 0.0 44 4.3 0.0 2.1 2 0 0 2 2 2 0 Brain expressed X-linked like family ecTbetaR2 PF08917.5 CCF48355.1 - 8.6 6.1 0.0 20 4.9 0.0 1.5 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain AMP-binding PF00501.23 CCF48356.1 - 2.6e-79 266.5 0.0 3.6e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 CCF48356.1 - 1.3e-16 60.2 0.1 4.5e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.20 CCF48356.1 - 1.7e-08 34.6 0.0 6.8e-08 32.6 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CCF48356.1 - 6.2e-05 23.8 0.1 0.00024 21.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CD34_antigen PF06365.7 CCF48357.1 - 0.18 11.4 0.3 14 5.2 0.0 2.3 1 1 1 2 2 2 0 CD34/Podocalyxin family Colicin_V PF02674.11 CCF48357.1 - 0.99 9.2 12.1 0.23 11.3 3.4 2.7 1 1 1 2 2 2 0 Colicin V production protein Thioesterase PF00975.15 CCF48360.1 - 7.4e-07 29.6 1.7 5.4e-05 23.5 0.6 2.7 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 CCF48360.1 - 1.3e-06 28.4 0.0 1.6e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48360.1 - 0.0017 18.1 0.1 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 CCF48361.1 - 4.6e-24 85.6 0.0 6.7e-23 81.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCF48361.1 - 2.5e-12 45.7 0.0 2.6e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CCF48361.1 - 6.1e-12 45.3 0.0 2.2e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCF48361.1 - 9.2e-12 45.0 0.0 0.00013 21.7 0.0 3.3 3 0 0 3 3 3 3 FAD-NAD(P)-binding K_oxygenase PF13434.1 CCF48361.1 - 1.2e-11 44.1 0.0 3.1e-07 29.6 0.0 3.1 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCF48361.1 - 3.6e-05 23.7 0.0 0.003 17.4 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF48361.1 - 3.9e-05 22.7 0.0 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CCF48361.1 - 0.001 18.2 0.0 0.023 13.7 0.0 2.4 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CCF48361.1 - 0.0024 18.2 0.0 0.0092 16.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF48361.1 - 0.23 9.8 0.2 0.84 8.0 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein FSH1 PF03959.8 CCF48362.1 - 2.8e-19 69.4 0.0 6.4e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCF48362.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCF48362.1 - 0.0023 17.4 0.5 0.051 13.0 0.3 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase p450 PF00067.17 CCF48363.1 - 7e-64 216.0 0.0 1.1e-63 215.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Erf4 PF10256.4 CCF48364.1 - 2.3e-13 50.0 0.0 5.7e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Pyridoxal_deC PF00282.14 CCF48365.1 - 4.4e-60 203.1 0.0 1e-58 198.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 CCF48365.1 - 4.9e-07 29.1 0.0 4e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCF48365.1 - 0.0043 15.8 0.0 0.0064 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HTH_6 PF01418.12 CCF48365.1 - 0.1 12.3 0.1 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family Aa_trans PF01490.13 CCF48367.1 - 4e-05 22.2 6.6 0.021 13.2 4.5 2.4 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein zf-RING_2 PF13639.1 CCF48368.1 - 1.2e-11 44.2 11.0 5.3e-08 32.5 1.9 3.1 2 2 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CCF48368.1 - 1.6e-05 24.9 6.2 4.2e-05 23.5 0.4 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCF48368.1 - 9e-05 22.0 0.6 9e-05 22.0 0.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF48368.1 - 0.00029 20.7 11.7 0.0019 18.2 1.4 3.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF48368.1 - 0.00053 19.6 11.4 0.0032 17.1 0.4 3.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCF48368.1 - 0.00093 18.9 0.5 0.00093 18.9 0.3 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCF48368.1 - 0.0017 17.9 11.9 0.007 16.0 0.7 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.4 CCF48368.1 - 0.15 12.2 2.1 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RINGv PF12906.2 CCF48368.1 - 0.35 10.9 7.3 0.09 12.8 1.7 2.4 2 0 0 2 2 2 0 RING-variant domain AsnC_trans_reg PF01037.16 CCF48369.1 - 0.23 11.2 0.0 0.43 10.3 0.0 1.4 1 0 0 1 1 1 0 AsnC family GILT PF03227.11 CCF48370.1 - 5.5e-06 26.1 1.2 8.7e-06 25.5 0.2 1.8 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) 4HBT PF03061.17 CCF48371.1 - 5.8e-07 29.5 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Pkinase PF00069.20 CCF48372.1 - 1e-58 198.5 0.0 1.9e-58 197.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 CCF48372.1 - 5.1e-58 196.1 0.0 8.5e-58 195.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 CCF48372.1 - 5e-41 140.4 0.0 3.3e-40 137.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF48372.1 - 0.0024 16.8 0.0 0.01 14.8 0.0 2.1 1 1 0 1 1 1 1 Kinase-like WD40 PF00400.27 CCF48374.1 - 2.4e-38 128.6 17.6 1.9e-09 37.0 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF3312 PF11768.3 CCF48374.1 - 0.0051 15.1 0.2 0.016 13.4 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) DUF4613 PF15390.1 CCF48374.1 - 0.065 11.4 0.4 0.12 10.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IKI3 PF04762.7 CCF48374.1 - 0.096 10.4 0.1 0.14 9.9 0.1 1.4 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.1 CCF48374.1 - 0.32 11.3 0.1 0.32 11.3 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain MutS_V PF00488.16 CCF48375.1 - 4.6e-57 193.1 0.0 8e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCF48375.1 - 3.9e-11 43.1 3.7 3.9e-11 43.1 2.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CCF48375.1 - 2.3e-06 27.6 0.1 4.8e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CCF48375.1 - 1.1e-05 25.5 0.2 3.6e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 CCF48375.1 - 0.0028 17.1 0.0 0.0076 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF48375.1 - 0.023 14.8 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCF48375.1 - 0.062 13.6 0.0 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCF48375.1 - 0.11 11.8 0.2 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_L7Ae PF01248.21 CCF48376.1 - 9.8e-28 95.5 0.1 1.2e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCF48376.1 - 0.006 16.4 0.0 0.0071 16.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 CCF48376.1 - 0.043 13.5 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain HTH_Crp_2 PF13545.1 CCF48376.1 - 0.077 12.7 0.0 0.34 10.7 0.0 2.1 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Arrestin_N PF00339.24 CCF48378.1 - 4.2e-05 23.4 0.0 9.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain UPF0203 PF05254.7 CCF48379.1 - 1.4e-12 47.3 0.9 1e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) DUF1180 PF06679.7 CCF48379.1 - 7.3 6.4 12.2 0.94 9.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) 3Beta_HSD PF01073.14 CCF48380.1 - 1.7e-17 63.0 0.0 2.8e-17 62.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCF48380.1 - 4.8e-17 62.1 0.0 9e-17 61.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCF48380.1 - 8.1e-15 54.4 0.0 6e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCF48380.1 - 3.9e-14 53.0 0.0 9.5e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCF48380.1 - 1.9e-06 27.3 0.1 3.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 CCF48380.1 - 0.00035 20.5 0.0 0.00082 19.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCF48380.1 - 0.0019 17.1 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCF48380.1 - 0.012 15.3 0.1 0.087 12.4 0.1 2.1 1 1 0 1 1 1 0 KR domain Ldh_1_N PF00056.18 CCF48380.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCF48380.1 - 0.11 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ribonuc_red_sm PF00268.16 CCF48381.1 - 1.3e-115 385.2 1.7 1.5e-115 385.0 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Abhydrolase_6 PF12697.2 CCF48382.1 - 6.1e-08 32.8 0.0 8.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48382.1 - 2e-07 30.8 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCF48382.1 - 0.00038 20.2 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 CCF48382.1 - 0.00089 18.8 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCF48382.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 CCF48382.1 - 0.023 14.0 0.0 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.17 CCF48382.1 - 0.039 13.6 0.1 3.6 7.2 0.0 2.6 1 1 1 2 2 2 0 Cutinase Abhydrolase_1 PF00561.15 CCF48382.1 - 0.047 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 CCF48382.1 - 0.096 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Aldolase_II PF00596.16 CCF48383.1 - 3e-23 82.3 0.0 4.5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2647 PF10839.3 CCF48383.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2647) DUF3533 PF12051.3 CCF48384.1 - 8.3e-92 307.8 19.8 9.7e-92 307.6 13.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) UPF0233 PF06781.7 CCF48384.1 - 0.86 9.2 0.0 0.86 9.2 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) HemY_N PF07219.8 CCF48384.1 - 2.5 7.7 0.0 2.5 7.7 0.0 3.3 4 0 0 4 4 4 0 HemY protein N-terminus PRK PF00485.13 CCF48386.1 - 3.8e-09 36.4 0.0 5.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CCF48386.1 - 3e-05 24.3 0.3 0.00082 19.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF48386.1 - 0.00019 22.2 0.0 0.00036 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF48386.1 - 0.011 15.6 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCF48386.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 CCF48386.1 - 0.024 13.5 0.3 0.035 13.0 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 CCF48386.1 - 0.14 12.1 0.3 0.34 10.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CCF48386.1 - 0.17 11.6 0.1 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 CCF48387.1 - 1.7e-66 222.7 0.0 1.9e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCF48387.1 - 6.9e-10 38.1 0.1 1.7e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CCF48387.1 - 1.7e-09 37.1 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CCF48387.1 - 7.5e-09 36.1 0.0 1e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCF48387.1 - 2e-08 33.7 0.0 2.3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CCF48387.1 - 2.7e-07 30.5 0.0 4.9e-07 29.6 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCF48387.1 - 1.4e-05 24.3 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF48387.1 - 0.0038 16.6 0.0 0.12 11.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCF48387.1 - 0.009 15.4 0.0 0.05 13.1 0.0 2.1 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.3 CCF48387.1 - 0.044 13.0 0.0 0.099 11.8 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) IF4E PF01652.13 CCF48388.1 - 1.1e-50 171.3 0.0 1.4e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Bromo_TP PF07524.8 CCF48389.1 - 2.5e-06 27.1 0.3 4.3e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 CCF48389.1 - 0.01 15.8 1.4 0.01 15.8 0.9 2.6 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Rhodanese PF00581.15 CCF48390.1 - 8.2e-08 32.5 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ECH PF00378.15 CCF48391.1 - 4e-37 127.6 0.4 8.8e-37 126.5 0.3 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CCF48391.1 - 0.029 14.1 0.0 0.089 12.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 Antimicrobial12 PF08107.6 CCF48393.1 - 0.069 12.7 0.4 0.097 12.2 0.2 1.3 1 0 0 1 1 1 0 Pleurocidin family Pkinase PF00069.20 CCF48395.1 - 1.8e-58 197.7 0.0 3.5e-33 114.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48395.1 - 3.4e-19 68.9 0.0 3.1e-17 62.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Elong_Iki1 PF10483.4 CCF48395.1 - 2.4e-18 66.5 0.1 1.5e-11 44.2 0.1 2.2 2 0 0 2 2 2 2 Elongator subunit Iki1 Kdo PF06293.9 CCF48395.1 - 0.0027 16.7 0.2 0.0052 15.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.16 CCF48396.1 - 3.9e-08 33.1 11.1 8.7e-07 28.8 7.8 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 CCF48396.1 - 3.7e-07 29.8 4.5 3.7e-07 29.8 3.1 1.6 1 1 1 2 2 2 1 Basic region leucine zipper DUF972 PF06156.8 CCF48396.1 - 0.015 15.6 0.3 0.038 14.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc7 PF08317.6 CCF48396.1 - 0.023 13.3 1.4 0.035 12.7 1.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_Maf PF03131.12 CCF48396.1 - 0.039 14.2 3.8 0.072 13.3 2.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.13 CCF48396.1 - 0.081 12.9 0.9 0.22 11.5 0.3 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Herpes_BLRF2 PF05812.7 CCF48396.1 - 0.17 11.7 3.1 0.26 11.0 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein IncA PF04156.9 CCF48396.1 - 0.21 11.1 2.4 0.35 10.4 1.7 1.2 1 0 0 1 1 1 0 IncA protein zf-CCHC PF00098.18 CCF48397.1 - 5.1e-10 38.7 12.0 1.4e-05 24.7 1.1 2.5 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 CCF48397.1 - 1.3e-06 27.9 0.5 2.3e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 CCF48397.1 - 2.6e-06 27.0 11.1 0.00042 19.9 2.0 2.6 1 1 1 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 CCF48397.1 - 5.4e-05 22.5 26.3 0.0004 19.7 6.4 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) KH_3 PF13014.1 CCF48397.1 - 0.00025 20.6 0.2 0.00058 19.4 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 CCF48397.1 - 3.1 7.5 10.2 6.8 6.4 1.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CCF48397.1 - 6.2 6.5 13.3 1.1 8.9 1.5 2.6 1 1 1 2 2 2 0 Zinc knuckle PRP21_like_P PF12230.3 CCF48399.1 - 0.14 11.6 3.5 0.1 12.0 0.2 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Syntaxin-6_N PF09177.6 CCF48401.1 - 8.3e-20 71.0 1.3 1.6e-19 70.0 0.1 2.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CCF48401.1 - 2.6e-11 43.0 3.1 2.6e-11 43.0 2.1 2.1 2 0 0 2 2 2 1 SNARE domain DUF2959 PF11172.3 CCF48401.1 - 0.11 12.2 1.9 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF1664 PF07889.7 CCF48401.1 - 0.74 9.6 2.6 21 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CCF48401.1 - 0.98 9.3 3.1 8.7 6.3 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TFIID-31kDa PF02291.10 CCF48402.1 - 9.1e-40 135.4 0.0 1.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 CCF48402.1 - 0.0033 17.1 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Ribosomal_S14 PF00253.16 CCF48403.1 - 1.1e-20 72.7 0.4 7.8e-20 70.0 0.0 2.3 2 1 1 3 3 3 1 Ribosomal protein S14p/S29e COX7C PF02935.11 CCF48403.1 - 0.18 11.6 0.5 0.35 10.6 0.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc SIP1 PF04938.7 CCF48404.1 - 3.6e-14 52.6 0.2 1.8e-13 50.4 0.1 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) MFS_1 PF07690.11 CCF48405.1 - 4.8e-32 111.0 35.3 1.3e-29 103.0 10.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF48405.1 - 3.3e-17 62.2 4.1 3.3e-17 62.2 2.8 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter COX15-CtaA PF02628.10 CCF48406.1 - 7.2e-77 258.2 13.7 2.1e-76 256.6 9.5 1.8 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosomal_L19 PF01245.15 CCF48407.1 - 4.2e-27 94.1 0.3 6.3e-27 93.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.10 CCF48408.1 - 8.5e-97 322.9 25.2 1.2e-96 322.4 17.5 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCF48408.1 - 1.4e-45 154.4 12.5 4.4e-45 152.8 8.6 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 CCF48408.1 - 0.003 17.0 2.7 0.008 15.7 1.9 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) MbeD_MobD PF04899.7 CCF48408.1 - 0.0081 16.0 1.4 0.58 10.0 0.0 2.7 2 0 0 2 2 2 1 MbeD/MobD like Cep57_MT_bd PF06657.8 CCF48408.1 - 0.26 11.2 6.3 0.054 13.4 1.3 2.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ribonuclease_3 PF00636.21 CCF48410.1 - 1.2e-29 103.0 0.0 3.3e-13 50.0 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCF48410.1 - 1.7e-16 60.3 0.0 1.8e-06 27.9 0.0 4.0 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 CCF48410.1 - 2.1e-15 56.2 0.1 4.7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 CCF48410.1 - 1.1e-11 44.4 0.1 3.1e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF48410.1 - 1.2e-10 41.2 0.0 4.1e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCF48410.1 - 9.3e-06 25.5 0.0 6.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 CCF48410.1 - 0.07 13.7 0.1 0.22 12.1 0.1 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF3439 PF11921.3 CCF48410.1 - 0.097 12.4 1.0 0.24 11.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) cwf21 PF08312.7 CCF48411.1 - 1.7e-15 56.5 13.2 1.7e-15 56.5 9.2 2.5 2 0 0 2 2 2 1 cwf21 domain C2 PF00168.25 CCF48412.1 - 3.7e-12 45.9 0.0 3.2e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain WLM PF08325.5 CCF48413.1 - 1.1e-28 100.3 0.1 2.3e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 CCF48413.1 - 0.021 14.5 0.8 0.037 13.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 ubiquitin PF00240.18 CCF48413.1 - 0.07 12.5 0.5 0.22 10.9 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin family Acyl-CoA_dh_1 PF00441.19 CCF48414.1 - 2.3e-25 89.4 4.4 3.4e-25 88.8 3.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF48414.1 - 2.7e-14 52.4 0.1 7.8e-14 50.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CCF48414.1 - 2.8e-11 43.7 4.9 5.1e-11 42.9 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCF48414.1 - 2.6e-10 40.8 0.0 6.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SLAC1 PF03595.12 CCF48415.1 - 1.3e-80 270.5 42.5 1.5e-80 270.3 29.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HCV_NS2 PF01538.13 CCF48415.1 - 0.22 10.9 2.8 0.53 9.7 2.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS2 MCM PF00493.18 CCF48416.1 - 1.7e-132 441.2 0.0 1.3e-131 438.3 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCF48416.1 - 1.1e-28 100.1 0.0 4.5e-28 98.1 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CCF48416.1 - 6.8e-08 32.3 0.0 3.8e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCF48416.1 - 1.8e-07 30.5 0.1 1.7e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCF48416.1 - 0.029 13.9 0.0 0.13 11.8 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF48416.1 - 0.13 11.7 0.1 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Ras PF00071.17 CCF48417.1 - 3e-43 147.0 0.1 4.5e-41 139.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCF48417.1 - 6.3e-20 71.8 0.6 1.5e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCF48417.1 - 1.7e-11 43.7 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF48417.1 - 0.00045 20.1 0.0 0.00086 19.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCF48417.1 - 0.00055 19.1 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCF48417.1 - 0.0014 17.8 0.0 0.0041 16.3 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CCF48417.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCF48417.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AhpC-TSA PF00578.16 CCF48418.1 - 2.5e-33 114.3 0.0 3.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCF48418.1 - 1.2e-11 44.3 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CCF48418.1 - 3.9e-10 39.2 0.0 6.8e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 CCF48418.1 - 0.046 13.6 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme AMMECR1 PF01871.12 CCF48419.1 - 2.2e-36 124.5 0.0 2.2e-27 95.2 0.0 2.1 2 0 0 2 2 2 2 AMMECR1 TspO_MBR PF03073.10 CCF48420.1 - 5.6e-47 158.9 9.4 6.4e-47 158.7 6.5 1.0 1 0 0 1 1 1 1 TspO/MBR family His_Phos_2 PF00328.17 CCF48421.1 - 1.3e-72 245.0 0.1 1.9e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCF48421.1 - 6.1e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain SBDS PF01172.13 CCF48423.1 - 9.5e-15 54.1 0.1 1.1e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF5 PF04855.7 CCF48424.1 - 2.1e-67 227.1 1.8 1.6e-64 217.7 0.2 2.2 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 tRNA-synt_2 PF00152.15 CCF48425.1 - 2e-100 335.8 0.0 2.8e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCF48425.1 - 3.4e-06 26.8 0.0 6.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCF48425.1 - 0.0026 17.3 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CCF48425.1 - 0.014 14.5 0.0 0.82 8.8 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) LIM PF00412.17 CCF48426.1 - 1.8e-28 98.3 34.0 9.4e-14 51.2 1.7 5.1 4 1 0 4 4 4 4 LIM domain NAM-associated PF14303.1 CCF48428.1 - 0.43 10.8 3.9 0.16 12.3 0.8 1.7 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain ketoacyl-synt PF00109.21 CCF48429.1 - 3.6e-55 187.1 0.1 7e-55 186.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.20 CCF48429.1 - 2.2e-21 75.8 3.1 4.9e-10 39.5 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 CCF48429.1 - 7.6e-20 72.1 0.0 1.4e-17 64.6 0.0 3.6 3 1 0 3 3 3 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 CCF48429.1 - 7.1e-14 51.6 0.3 1.9e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Abhydrolase_5 PF12695.2 CCF48429.1 - 0.0044 16.7 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3263 PF11662.3 CCF48431.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Zn_clus PF00172.13 CCF48432.1 - 0.0013 18.6 6.3 0.28 11.1 0.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain VIGSSK PF14773.1 CCF48432.1 - 2.4 8.1 6.8 0.43 10.5 0.1 3.2 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal BAF1_ABF1 PF04684.8 CCF48432.1 - 5.1 5.8 13.4 11 4.6 9.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ndc1_Nup PF09531.5 CCF48433.1 - 1.5e-73 248.2 5.2 2.5e-73 247.5 3.6 1.3 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DDHD PF02862.12 CCF48433.1 - 4 7.1 6.2 14 5.4 4.3 1.9 1 1 0 1 1 1 0 DDHD domain Sod_Fe_C PF02777.13 CCF48434.1 - 9.9e-19 67.1 0.6 2.2e-08 33.9 0.2 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain ketoacyl-synt PF00109.21 CCF48435.1 - 4.4e-50 170.5 0.1 7.4e-50 169.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 CCF48435.1 - 2.2e-47 161.9 0.0 1.1e-46 159.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 CCF48435.1 - 4.4e-29 100.7 0.2 1.5e-28 99.0 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 CCF48435.1 - 1.3e-23 84.4 0.0 5e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 CCF48435.1 - 1.6e-17 63.5 0.0 3.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 CCF48435.1 - 9.6e-07 28.9 0.1 0.00032 20.6 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48435.1 - 1.8e-05 24.4 0.1 0.23 11.2 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 CCF48435.1 - 0.00071 18.6 4.0 0.0059 15.6 0.2 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain FSH1 PF03959.8 CCF48436.1 - 2.4e-20 72.9 0.0 4.6e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) SNARE_assoc PF09335.6 CCF48437.1 - 3.6e-14 53.0 4.0 1e-13 51.5 2.8 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein UPF0160 PF03690.8 CCF48438.1 - 1e-121 406.2 0.0 1.3e-121 405.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) cobW PF02492.14 CCF48438.1 - 2.7e-36 124.6 0.0 4.2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CCF48438.1 - 6.9e-05 21.7 1.6 0.00024 19.9 1.1 1.7 1 1 0 1 1 1 1 ArgK protein Pox_A32 PF04665.7 CCF48438.1 - 0.0029 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_17 PF13207.1 CCF48438.1 - 0.004 17.9 0.1 0.015 16.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF48438.1 - 0.0067 16.4 1.2 0.17 11.8 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCF48438.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 CCF48438.1 - 0.013 15.1 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CCF48438.1 - 0.02 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CCF48438.1 - 0.027 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CCF48438.1 - 0.03 14.4 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCF48438.1 - 0.043 13.5 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase KAP_NTPase PF07693.9 CCF48438.1 - 0.056 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.18 CCF48438.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CCF48438.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCF48438.1 - 0.11 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain APH PF01636.18 CCF48439.1 - 2e-37 129.1 0.0 3.1e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCF48439.1 - 8.9e-07 28.3 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 CCF48439.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SLT_L PF14718.1 CCF48439.1 - 0.34 10.7 5.8 0.5 10.1 0.1 2.4 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Aldedh PF00171.17 CCF48440.1 - 2.2e-76 257.0 0.0 2.6e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhaP_Bmeg PF09602.5 CCF48440.1 - 0.038 13.8 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) BTB PF00651.26 CCF48441.1 - 5.7e-07 29.5 0.0 3.8e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Acyltransferase PF01553.16 CCF48442.1 - 3.3e-33 113.9 0.0 5.3e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Glyco_hydro_3 PF00933.16 CCF48443.1 - 1.1e-55 188.6 0.0 1.9e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCF48443.1 - 1.4e-37 129.4 0.0 2.2e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCF48443.1 - 6.3e-10 38.8 0.0 1.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 CCF48443.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 CARDB UBN2 PF14223.1 CCF48444.1 - 0.0024 17.6 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type PBP1_TM PF14812.1 CCF48444.1 - 0.19 12.0 3.2 8.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_2 PF07727.9 CCF48445.1 - 5.3e-38 130.3 0.0 9.9e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF48445.1 - 1.7e-09 37.8 0.1 3.3e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF48445.1 - 8.5e-07 28.5 0.1 2.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF936 PF06075.7 CCF48446.1 - 0.098 11.5 0.2 0.15 10.9 0.1 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF936) MoCF_biosynth PF00994.19 CCF48447.1 - 1.9e-14 53.2 0.1 6.5e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain AAA_2 PF07724.9 CCF48448.1 - 1.7e-47 161.5 0.2 8.6e-46 155.9 0.0 3.1 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCF48448.1 - 6.3e-26 91.1 0.0 4.5e-16 59.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCF48448.1 - 1.6e-17 63.1 0.7 6.1e-17 61.2 0.1 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCF48448.1 - 7.1e-15 54.9 0.0 2.3e-09 37.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF48448.1 - 1e-13 51.7 0.5 7.4e-05 22.8 0.0 4.9 2 2 0 4 4 4 2 AAA ATPase domain Clp_N PF02861.15 CCF48448.1 - 2.9e-13 49.5 6.5 2.4e-06 27.3 0.6 4.0 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 CCF48448.1 - 3.5e-09 36.3 0.0 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 CCF48448.1 - 1.6e-08 34.7 0.2 0.0055 16.8 0.0 4.6 3 2 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CCF48448.1 - 3.2e-07 29.6 0.1 0.0012 17.9 0.0 3.9 3 1 1 4 4 4 1 Zeta toxin Mg_chelatase PF01078.16 CCF48448.1 - 5.1e-05 22.5 0.4 0.43 9.7 0.1 3.8 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCF48448.1 - 0.00014 22.2 0.4 0.83 9.9 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 CCF48448.1 - 0.00026 20.5 1.7 1.9 7.8 0.0 4.0 3 1 1 4 4 4 2 AAA-like domain IstB_IS21 PF01695.12 CCF48448.1 - 0.00035 20.0 0.0 0.034 13.5 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCF48448.1 - 0.00038 21.2 4.4 0.66 10.8 0.6 3.8 2 1 1 3 3 2 2 AAA domain AAA_33 PF13671.1 CCF48448.1 - 0.00045 20.1 0.6 0.88 9.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain TrwB_AAD_bind PF10412.4 CCF48448.1 - 0.00051 18.7 0.0 1.9 7.0 0.0 3.4 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 CCF48448.1 - 0.00065 19.4 0.1 0.08 12.7 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CCF48448.1 - 0.0015 18.5 2.6 0.23 11.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain Torsin PF06309.6 CCF48448.1 - 0.002 18.0 0.0 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.17 CCF48448.1 - 0.0021 18.2 0.1 4.9 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.7 CCF48448.1 - 0.0035 17.0 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 CCF48448.1 - 0.0058 16.1 0.1 4 7.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain EMP24_GP25L PF01105.19 CCF48448.1 - 0.0086 15.8 2.0 0.019 14.7 1.4 1.5 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AAA_25 PF13481.1 CCF48448.1 - 0.014 14.7 1.8 3 7.2 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF258 PF03193.11 CCF48448.1 - 0.015 14.4 0.0 0.96 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 CbiA PF01656.18 CCF48448.1 - 0.016 14.6 0.7 0.74 9.1 0.0 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 CCF48448.1 - 0.025 14.1 0.0 14 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 CCF48448.1 - 0.03 14.0 0.0 8.4 6.1 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CCF48448.1 - 0.031 13.9 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CCF48448.1 - 0.04 14.2 3.2 11 6.2 0.0 4.0 4 0 0 4 4 4 0 ABC transporter AAA_3 PF07726.6 CCF48448.1 - 0.051 13.1 0.0 8.4 6.0 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCF48448.1 - 0.22 11.2 7.2 0.5 10.0 0.0 4.2 4 1 0 5 5 5 0 Archaeal ATPase Cytochrom_B561 PF03188.11 CCF48449.1 - 3.1e-09 36.7 12.3 3.1e-09 36.7 8.5 2.1 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 CCF48449.1 - 8.1e-06 25.7 0.2 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.1 CCF48449.1 - 0.00013 22.0 6.3 0.00013 22.0 4.4 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF4079) DUF2427 PF10348.4 CCF48449.1 - 0.0039 16.7 7.5 0.0039 16.7 5.2 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF2427) DUF3995 PF13160.1 CCF48449.1 - 0.012 15.7 0.9 0.012 15.7 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) OpgC_C PF10129.4 CCF48449.1 - 0.092 11.4 13.3 0.19 10.3 9.2 1.5 1 0 0 1 1 1 0 OpgC protein E1-E2_ATPase PF00122.15 CCF48450.1 - 4.7e-53 179.5 2.6 7.3e-53 178.9 1.2 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF48450.1 - 8.1e-36 123.2 7.6 8.1e-36 123.2 5.3 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF48450.1 - 4.3e-32 112.2 0.0 1e-31 111.0 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF48450.1 - 8e-17 60.9 0.0 1.9e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCF48450.1 - 4.2e-16 59.6 0.0 1.3e-15 58.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF48450.1 - 6.9e-12 44.6 0.0 2e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCF48450.1 - 0.00067 19.3 0.6 0.0013 18.3 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 CCF48450.1 - 0.077 13.3 2.0 1 9.7 0.2 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF2207 PF09972.4 CCF48450.1 - 0.2 10.2 2.3 3.1 6.2 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1049 PF06305.6 CCF48450.1 - 0.36 10.3 4.0 1.5 8.3 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF805 PF05656.9 CCF48450.1 - 4.1 7.2 14.6 0.046 13.5 1.3 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF805) Herpes_gE PF02480.11 CCF48451.1 - 0.0037 15.5 0.0 0.0062 14.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Orthoreo_P10 PF07204.6 CCF48451.1 - 0.019 14.7 0.2 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 EphA2_TM PF14575.1 CCF48451.1 - 0.038 14.3 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 CCF48451.1 - 0.039 13.3 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Utp12 PF04003.7 CCF48452.1 - 0.005 16.7 0.6 0.0069 16.2 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Dict-STAT-coil PF09267.5 CCF48452.1 - 0.048 13.8 1.2 0.061 13.5 0.8 1.2 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Adeno_E4_ORF3 PF06931.6 CCF48452.1 - 0.09 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein TMPIT PF07851.8 CCF48452.1 - 0.099 11.6 1.6 0.11 11.5 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.10 CCF48452.1 - 0.17 11.0 2.5 0.19 10.8 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RVT_2 PF07727.9 CCF48453.1 - 2.3e-53 180.6 0.1 3.1e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.1 CCF48454.1 - 1.7e-40 138.5 0.1 2.8e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCF48454.1 - 2.2e-28 99.4 0.1 4.6e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF48454.1 - 1.4e-10 40.8 0.3 6.1e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain zf-CCCH PF00642.19 CCF48454.1 - 2.1e-10 40.0 14.4 8.4e-06 25.3 2.1 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_30 PF13604.1 CCF48454.1 - 1.7e-07 30.9 0.1 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CCF48454.1 - 5.2e-06 25.6 0.0 0.017 14.1 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 CCF48454.1 - 0.00017 21.0 0.0 0.00046 19.5 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF4372 PF14294.1 CCF48454.1 - 0.018 14.9 0.1 0.081 12.8 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) AAA_26 PF13500.1 CCF48454.1 - 0.033 13.7 0.3 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCF48454.1 - 0.065 12.1 0.1 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CCF48454.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 CCF48454.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit gag_pre-integrs PF13976.1 CCF48455.1 - 0.00012 21.6 1.8 0.00023 20.7 1.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCF48456.1 - 0.06 13.2 3.9 0.19 11.7 2.7 1.9 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 CCF48458.1 - 3.3e-15 56.2 0.0 7.8e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MiaE PF06175.6 CCF48458.1 - 0.037 13.3 0.2 0.073 12.4 0.2 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RVT_2 PF07727.9 CCF48459.1 - 2.3e-25 89.0 0.1 2.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Iron_traffic PF04362.9 CCF48461.1 - 0.084 12.3 2.7 0.072 12.5 0.9 1.6 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking Gti1_Pac2 PF09729.4 CCF48461.1 - 0.15 11.8 0.6 0.18 11.6 0.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Abhydrolase_5 PF12695.2 CCF48462.1 - 4.5e-06 26.4 0.7 7.3e-06 25.7 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF48462.1 - 0.00047 20.1 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCF48462.1 - 0.0014 18.2 0.1 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CCF48462.1 - 0.019 14.5 0.3 0.03 13.8 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-Tim10_DDP PF02953.10 CCF48463.1 - 4.8e-19 67.4 3.2 4.8e-19 67.4 2.2 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DUF1178 PF06676.6 CCF48463.1 - 0.055 13.6 0.3 0.12 12.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) DFF-C PF09033.5 CCF48463.1 - 0.084 12.6 0.1 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain eIF-6 PF01912.13 CCF48464.1 - 5.5e-82 273.6 0.4 7.5e-82 273.2 0.1 1.3 2 0 0 2 2 2 1 eIF-6 family PRKCSH-like PF12999.2 CCF48465.1 - 3.7e-45 153.6 6.5 3.7e-45 153.6 4.5 1.9 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCF48465.1 - 9.9e-30 103.0 1.0 3.4e-29 101.3 0.2 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CCF48465.1 - 1.2e-10 42.0 2.4 3.7e-10 40.4 1.6 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 CCF48465.1 - 0.12 12.2 15.8 0.99 9.3 1.0 3.3 3 0 0 3 3 3 0 Low-density lipoprotein receptor domain class A Tctex-1 PF03645.8 CCF48466.1 - 1.7e-05 24.5 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family RNA_Me_trans PF04252.8 CCF48467.1 - 5.7e-25 87.8 0.0 2.3e-19 69.5 0.0 3.1 2 1 0 2 2 2 2 Predicted SAM-dependent RNA methyltransferase GTP_cyclohydroI PF01227.17 CCF48468.1 - 2e-72 242.1 0.1 2.7e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCF48468.1 - 0.0015 18.4 0.0 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 CCF48468.1 - 0.011 15.5 0.1 0.037 13.8 0.1 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BolA PF01722.13 CCF48469.1 - 1.8e-14 53.4 0.0 2.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_S25 PF03297.10 CCF48470.1 - 6.5e-42 141.8 3.1 7.2e-42 141.6 2.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein BioT2 PF15368.1 CCF48470.1 - 0.068 12.9 0.7 0.077 12.7 0.4 1.3 1 1 0 1 1 1 0 Spermatogenesis family BioT2 HTH_24 PF13412.1 CCF48470.1 - 0.068 12.5 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PulS_OutS PF09691.5 CCF48470.1 - 0.16 12.0 1.4 0.37 10.8 0.6 1.7 1 1 1 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) Mt_ATP-synt_D PF05873.7 CCF48471.1 - 1.9e-12 47.1 2.2 2.2e-12 46.9 1.5 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DivIC PF04977.10 CCF48471.1 - 0.007 15.8 4.1 0.23 10.9 0.2 2.4 2 0 0 2 2 2 1 Septum formation initiator V_ATPase_I PF01496.14 CCF48471.1 - 0.056 11.3 2.1 0.068 11.0 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2e PF02091.10 CCF48471.1 - 0.058 12.4 0.6 0.072 12.1 0.4 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Gcd10p PF04189.8 CCF48471.1 - 0.096 11.8 2.2 0.12 11.4 1.3 1.3 1 1 0 1 1 1 0 Gcd10p family DUF1366 PF07104.6 CCF48471.1 - 0.12 12.0 3.0 0.21 11.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) IncA PF04156.9 CCF48471.1 - 0.12 11.9 5.0 0.18 11.3 3.5 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_M17_N PF02789.12 CCF48471.1 - 0.13 12.0 0.2 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Prominin PF05478.6 CCF48471.1 - 0.26 8.7 3.1 0.29 8.6 2.2 1.0 1 0 0 1 1 1 0 Prominin MscS_porin PF12795.2 CCF48471.1 - 0.32 10.2 13.7 1 8.5 2.9 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF2408 PF10303.4 CCF48471.1 - 0.34 11.0 5.6 0.71 9.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prefoldin_2 PF01920.15 CCF48471.1 - 0.37 10.5 9.4 1.9 8.3 6.5 2.0 1 1 0 1 1 1 0 Prefoldin subunit WXG100 PF06013.7 CCF48471.1 - 0.47 10.4 6.1 2.1 8.4 0.6 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Flagellin_N PF00669.15 CCF48471.1 - 0.53 10.0 5.3 1.3 8.8 3.5 1.9 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF2564 PF10819.3 CCF48471.1 - 0.72 10.0 6.7 0.67 10.1 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) Snf7 PF03357.16 CCF48471.1 - 0.88 8.9 8.2 0.14 11.4 1.2 2.2 1 1 0 2 2 2 0 Snf7 FlxA PF14282.1 CCF48471.1 - 2.6 8.0 13.5 7.8 6.5 1.4 2.2 1 1 1 2 2 2 0 FlxA-like protein DUF2570 PF10828.3 CCF48471.1 - 3.3 7.3 9.5 1.5 8.4 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) PRP1_N PF06424.7 CCF48471.1 - 3.6 7.9 5.8 29 4.9 4.1 2.0 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3573 PF12097.3 CCF48471.1 - 4.8 5.6 5.8 5 5.6 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) cNMP_binding PF00027.24 CCF48472.1 - 2e-39 133.2 0.1 4.8e-19 67.9 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CCF48472.1 - 1.2e-16 59.8 0.2 2.5e-16 58.8 0.2 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.6 CCF48472.1 - 0.056 12.9 0.5 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Cupin domain SR-25 PF10500.4 CCF48472.1 - 0.21 11.0 4.1 0.36 10.2 2.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aft1_HRA PF11786.3 CCF48474.1 - 3.1e-19 68.9 14.0 1.3e-18 67.0 7.1 3.5 3 0 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 CCF48474.1 - 1.5e-09 37.6 8.7 2.9e-09 36.7 6.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCF48474.1 - 4.5e-07 29.5 9.1 1.2e-06 28.2 6.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Aft1_OSA PF11785.3 CCF48474.1 - 0.00024 21.5 0.7 0.00024 21.5 0.5 4.4 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_Maf PF03131.12 CCF48474.1 - 0.00033 20.8 4.7 0.00033 20.8 3.2 1.9 2 0 0 2 2 2 1 bZIP Maf transcription factor Shugoshin_N PF07558.6 CCF48474.1 - 0.0013 18.3 0.6 0.0028 17.3 0.4 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 CCF48474.1 - 0.07 13.4 0.6 0.07 13.4 0.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) DUF3972 PF13118.1 CCF48474.1 - 0.14 12.2 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) HALZ PF02183.13 CCF48474.1 - 0.4 10.4 3.4 0.17 11.5 0.7 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glypican PF01153.14 CCF48474.1 - 1.3 7.5 5.4 0.58 8.7 2.0 1.4 1 1 0 1 1 1 0 Glypican TSC22 PF01166.13 CCF48474.1 - 8.2 6.4 6.1 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family DAO PF01266.19 CCF48475.1 - 0.0038 16.1 0.1 0.005 15.7 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Transaldolase PF00923.14 CCF48476.1 - 3.3e-32 111.7 0.2 4.7e-32 111.2 0.0 1.3 2 0 0 2 2 2 1 Transaldolase Cupin_2 PF07883.6 CCF48477.1 - 9.2e-05 21.8 1.5 0.064 12.7 0.0 3.5 4 0 0 4 4 4 2 Cupin domain Cupin_3 PF05899.7 CCF48477.1 - 0.0021 17.3 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) PMI_typeI PF01238.16 CCF48477.1 - 0.0076 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CCF48477.1 - 0.016 14.9 0.6 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain Cupin_6 PF12852.2 CCF48477.1 - 0.016 14.8 0.1 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 Cupin JmjC PF02373.17 CCF48477.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Abhydrolase_6 PF12697.2 CCF48478.1 - 2.7e-13 50.3 0.0 3.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48478.1 - 3.6e-11 42.9 0.0 5e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF48478.1 - 1.5e-07 30.8 3.2 9.1e-07 28.3 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1749 PF08538.5 CCF48478.1 - 3.2e-06 26.2 0.1 0.00014 20.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.3 CCF48478.1 - 0.0018 18.0 0.1 0.0098 15.7 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCF48478.1 - 0.0018 17.8 0.4 0.0066 16.0 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CCF48478.1 - 0.0025 17.3 2.1 0.11 11.8 0.2 2.3 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 CCF48478.1 - 0.0026 17.2 0.0 0.0097 15.3 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Tannase PF07519.6 CCF48478.1 - 0.042 12.5 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase rve PF00665.21 CCF48482.1 - 1.5e-11 44.4 0.0 2.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF48482.1 - 9.4e-11 41.2 0.1 2.5e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CCF48482.1 - 0.37 10.3 1.7 0.6 9.6 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain gag_pre-integrs PF13976.1 CCF48485.1 - 1.2e-06 28.1 0.0 3.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain PIGA PF08288.7 CCF48486.1 - 1.4e-44 150.3 0.4 2.6e-44 149.4 0.3 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCF48486.1 - 5.1e-24 84.6 0.0 8.6e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCF48486.1 - 2.2e-16 60.0 0.6 6.5e-16 58.5 0.2 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCF48486.1 - 1.9e-13 50.8 0.3 4.9e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCF48486.1 - 8e-11 42.2 0.0 1.5e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCF48486.1 - 6.8e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCF48486.1 - 0.0055 16.9 0.0 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 RRM_1 PF00076.17 CCF48487.1 - 4.1e-21 74.3 0.0 5.8e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48487.1 - 1.4e-17 63.4 0.0 2.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48487.1 - 4.3e-10 39.2 0.1 1e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF48487.1 - 0.048 13.4 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 GRP PF07172.6 CCF48487.1 - 0.19 12.2 10.8 0.048 14.1 4.8 2.0 2 0 0 2 2 2 0 Glycine rich protein family DUF2428 PF10350.4 CCF48488.1 - 1.1e-55 188.3 0.1 2.6e-55 187.2 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CCF48488.1 - 0.0011 18.8 9.1 1.2 9.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Yip1 PF04893.12 CCF48489.1 - 3.7e-08 33.0 11.0 6.9e-08 32.1 7.6 1.5 1 0 0 1 1 1 1 Yip1 domain DUF21 PF01595.15 CCF48490.1 - 9.4e-37 126.0 0.9 9.4e-37 126.0 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CCF48490.1 - 3.6e-07 29.8 1.3 0.0027 17.4 0.0 2.8 3 0 0 3 3 3 2 CBS domain TRP PF06011.7 CCF48491.1 - 4e-93 312.3 16.4 5.8e-93 311.8 11.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCF48491.1 - 1.4e-31 109.4 0.1 2.2e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCF48491.1 - 0.0099 16.1 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 ML domain DASH_Duo1 PF08651.5 CCF48494.1 - 4.4e-23 80.6 0.3 7.6e-23 79.8 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF572 PF04502.8 CCF48494.1 - 2.4 7.2 9.4 7.4 5.6 6.5 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) ABA_GPCR PF12430.3 CCF48495.1 - 4.5e-43 146.6 5.4 8.3e-43 145.8 3.7 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCF48495.1 - 1.1e-14 54.2 0.0 2.1e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) NADH-u_ox-rdase PF10785.4 CCF48495.1 - 0.13 12.5 0.9 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit IncA PF04156.9 CCF48496.1 - 0.0022 17.5 30.4 1.4 8.4 11.2 4.2 3 0 0 3 3 3 3 IncA protein TMF_DNA_bd PF12329.3 CCF48496.1 - 0.0026 17.5 3.2 0.0026 17.5 2.2 5.3 3 1 2 5 5 5 2 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CCF48496.1 - 0.014 15.7 26.4 0.038 14.3 0.5 5.3 3 1 2 5 5 5 0 Protein of unknown function (DUF972) DASH_Dam1 PF08653.5 CCF48496.1 - 0.12 12.1 2.0 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 TrmB PF01978.14 CCF48496.1 - 0.27 10.9 1.6 6.2 6.6 0.5 2.7 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Spectrin PF00435.16 CCF48496.1 - 0.45 10.8 21.3 3.3 8.0 0.7 4.8 4 1 1 5 5 5 0 Spectrin repeat Snapin_Pallidin PF14712.1 CCF48496.1 - 0.54 10.6 19.9 3.9 7.8 0.5 4.8 3 1 2 5 5 5 0 Snapin/Pallidin DUF2400 PF09674.5 CCF48496.1 - 2.3 7.8 5.3 6.5 6.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) DUF16 PF01519.11 CCF48496.1 - 4.4 7.5 9.1 3.5 7.9 2.9 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.7 CCF48496.1 - 8.5 6.1 12.6 0.36 10.6 2.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1749 PF08538.5 CCF48497.1 - 4.3e-63 213.0 0.0 6.2e-61 205.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CCF48497.1 - 2.5e-09 37.3 0.3 3.6e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48497.1 - 1.3e-07 31.4 0.0 3.1e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CCF48497.1 - 3.9e-06 26.5 0.2 9.9e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Chlorophyllase2 PF12740.2 CCF48497.1 - 0.00081 18.3 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF900 PF05990.7 CCF48497.1 - 0.0061 15.9 0.0 0.0094 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.16 CCF48497.1 - 0.0069 15.6 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2305 PF10230.4 CCF48497.1 - 0.0075 15.7 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase PF07224.6 CCF48497.1 - 0.052 12.3 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.15 CCF48497.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.10 CCF48497.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CS PF04969.11 CCF48498.1 - 0.00073 20.0 0.0 0.0093 16.4 0.0 2.4 1 1 0 1 1 1 1 CS domain CPSase_sm_chain PF00988.17 CCF48499.1 - 1.3e-43 147.6 0.0 2e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCF48499.1 - 3.5e-38 130.9 0.0 1.3e-37 129.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCF48499.1 - 1e-05 25.1 0.3 4.3e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 Peptidase_M22 PF00814.20 CCF48499.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family NAD_Gly3P_dh_C PF07479.9 CCF48500.1 - 3.6e-50 169.5 0.1 5.6e-50 168.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CCF48500.1 - 1.9e-48 164.1 0.1 3.5e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CCF48500.1 - 0.00046 20.5 0.1 0.0053 17.1 0.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PAS PF00989.19 CCF48500.1 - 0.069 12.9 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold CASP_C PF08172.7 CCF48501.1 - 6.9e-70 234.8 2.9 6.9e-70 234.8 2.0 4.9 2 2 1 3 3 3 1 CASP C terminal Homeobox PF00046.24 CCF48503.1 - 2.2e-16 59.2 2.0 5.6e-16 57.9 1.4 1.7 1 0 0 1 1 1 1 Homeobox domain FSH1 PF03959.8 CCF48505.1 - 1.8e-58 197.4 0.0 3.3e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cyt-b5 PF00173.23 CCF48505.1 - 4.5e-10 39.1 0.3 7.7e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_6 PF12697.2 CCF48505.1 - 2.3e-06 27.6 0.1 0.007 16.2 0.0 2.6 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCF48505.1 - 2e-05 24.1 0.2 9.9e-05 21.8 0.1 2.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCF48505.1 - 2.3e-05 24.1 0.0 4.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF48505.1 - 0.075 12.5 0.0 15 5.0 0.0 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CCF48505.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.4 CCF48505.1 - 0.14 10.9 0.2 4.4 6.0 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2048) LAG1-DNAbind PF09271.6 CCF48506.1 - 2.4e-39 135.0 1.0 5.4e-39 133.8 0.0 2.2 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CCF48506.1 - 3.2e-19 69.2 0.0 1.3e-17 64.0 0.0 2.9 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain Zn_clus PF00172.13 CCF48507.1 - 0.00082 19.2 9.1 0.00082 19.2 6.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.6 CCF48507.1 - 0.0025 17.8 0.0 0.0084 16.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 CCF48507.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.1 CCF48507.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain AT_hook PF02178.14 CCF48508.1 - 0.054 13.1 36.2 0.23 11.2 0.6 7.7 6 0 0 6 6 6 0 AT hook motif SPC22 PF04573.7 CCF48509.1 - 2.8e-42 143.9 0.7 3.3e-42 143.7 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Med11 PF10280.4 CCF48510.1 - 2.9e-06 27.3 0.5 1e-05 25.5 0.1 2.1 1 1 1 2 2 2 1 Mediator complex protein CsgG PF03783.9 CCF48510.1 - 0.045 12.8 4.8 0.052 12.6 2.5 1.7 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG FAA_hydrolase_N PF09298.6 CCF48510.1 - 7 6.7 9.4 0.34 10.9 2.1 2.1 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal ArfGap PF01412.13 CCF48511.1 - 1.1e-41 141.3 3.0 1.5e-41 140.8 2.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Abhydrolase_3 PF07859.8 CCF48512.1 - 1.2e-32 113.1 0.0 2.3e-23 82.8 0.0 2.8 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCF48512.1 - 0.065 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PPP4R2 PF09184.6 CCF48512.1 - 2.5 7.5 11.3 0.012 15.1 1.1 2.0 2 0 0 2 2 2 0 PPP4R2 FAD_binding_1 PF00667.15 CCF48513.1 - 2.4e-55 187.3 0.0 3.9e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCF48513.1 - 8e-35 119.9 0.4 2e-34 118.6 0.3 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCF48513.1 - 1.2e-21 77.3 0.0 6.6e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CCF48513.1 - 0.035 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain SQS_PSY PF00494.14 CCF48514.1 - 7.9e-74 248.3 4.7 1.1e-73 247.8 3.3 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF1765 PF08578.5 CCF48515.1 - 4.1e-31 107.6 1.6 6.8e-31 106.9 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) F5_F8_type_C PF00754.20 CCF48517.1 - 1.8e-07 31.0 0.1 2.4e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain RNase_H PF00075.19 CCF48518.1 - 1.6e-26 93.1 0.0 4.7e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 CCF48518.1 - 7.3e-17 61.1 3.0 1.4e-16 60.2 2.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin GPI-anchored PF10342.4 CCF48519.1 - 2.9e-07 30.8 0.3 6.1e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Trm112p PF03966.11 CCF48520.1 - 3.3e-18 65.8 0.5 7.1e-18 64.7 0.4 1.5 1 1 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.5 CCF48520.1 - 0.052 13.0 0.2 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain zf-NADH-PPase PF09297.6 CCF48520.1 - 0.06 12.8 0.4 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CCF48520.1 - 0.089 12.6 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Vps26 PF03643.10 CCF48521.1 - 5.3e-131 435.4 4.4 6.1e-131 435.2 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CCF48521.1 - 0.0034 17.2 1.9 1.1 9.1 0.1 3.3 2 2 1 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCF48521.1 - 0.0071 16.4 0.5 0.059 13.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RAP1 PF07218.6 CCF48522.1 - 6.3 4.7 7.2 9.3 4.2 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WD40 PF00400.27 CCF48523.1 - 9.9e-18 63.2 3.7 8e-07 28.7 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Arena_nucleocap PF00843.12 CCF48523.1 - 0.2 9.4 0.0 9.5 3.9 0.0 2.1 2 0 0 2 2 2 0 Arenavirus nucleocapsid protein Glyco_transf_22 PF03901.12 CCF48524.1 - 3.1e-72 243.8 0.0 5e-54 183.9 0.0 2.3 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family Tfb2 PF03849.9 CCF48525.1 - 3.3e-147 489.9 0.0 4.1e-147 489.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CCF48525.1 - 0.00024 20.8 0.1 0.0016 18.2 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Diphthamide_syn PF01866.12 CCF48526.1 - 1.3e-63 215.0 0.0 8.7e-39 133.5 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein DUF3663 PF12404.3 CCF48526.1 - 0.071 12.8 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Peptidase DUF3235 PF11574.3 CCF48526.1 - 0.16 12.2 1.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) VIT1 PF01988.14 CCF48527.1 - 4.1e-78 261.7 4.5 5.4e-78 261.3 3.1 1.2 1 0 0 1 1 1 1 VIT family RecX PF02631.11 CCF48527.1 - 0.17 12.0 1.7 0.29 11.3 1.2 1.3 1 0 0 1 1 1 0 RecX family MRC1 PF09444.5 CCF48528.1 - 5.5e-29 101.3 24.6 5.5e-29 101.3 17.1 8.1 8 1 0 8 8 8 1 MRC1-like domain Pept_tRNA_hydro PF01195.14 CCF48529.1 - 9e-18 64.4 0.4 1.2e-11 44.4 0.4 4.7 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Methyltransf_26 PF13659.1 CCF48529.1 - 1.3e-13 51.0 0.0 4.5e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF48529.1 - 3.5e-11 42.9 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF48529.1 - 5e-08 33.5 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF48529.1 - 5.3e-06 25.9 0.1 1.3e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 CCF48529.1 - 6.9e-05 22.0 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 CCF48529.1 - 0.00021 20.4 0.1 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CCF48529.1 - 0.00052 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF48529.1 - 0.00096 19.4 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCF48529.1 - 0.0061 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 CCF48529.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 CCF48529.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Aldo_ket_red PF00248.16 CCF48530.1 - 1.4e-64 217.7 0.0 1.5e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 CCF48532.1 - 3.2e-64 212.6 1.4 3.2e-21 74.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RAMP4 PF06624.7 CCF48534.1 - 0.00039 19.8 0.4 0.00039 19.8 0.2 1.7 2 0 0 2 2 2 1 Ribosome associated membrane protein RAMP4 ATG13 PF10033.4 CCF48535.1 - 5.7e-49 166.6 0.0 9.2e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 YedD PF13987.1 CCF48536.1 - 0.035 13.6 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 YedD-like protein LEA_6 PF10714.4 CCF48536.1 - 4.1 7.2 11.2 0.23 11.2 0.3 3.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Pkinase PF00069.20 CCF48537.1 - 9.9e-53 178.9 0.0 2.7e-52 177.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48537.1 - 7e-20 71.1 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF48537.1 - 0.0062 16.2 0.1 0.0062 16.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCF48537.1 - 0.021 14.1 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Ribosomal_S9 PF00380.14 CCF48539.1 - 1.1e-34 119.3 0.1 2e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2894 PF11445.3 CCF48539.1 - 0.062 13.5 0.3 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) RFX_DNA_binding PF02257.10 CCF48540.1 - 2.2e-25 88.5 0.1 5.7e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 CCF48540.1 - 0.0031 17.7 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 Poxvirus D5 protein-like BPL_LplA_LipB PF03099.14 CCF48542.1 - 4.2e-09 36.4 0.0 1.1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DEAD PF00270.24 CCF48543.1 - 5.6e-39 133.3 0.0 1e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48543.1 - 1.4e-18 66.5 0.0 2.8e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF48543.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCF48543.1 - 0.056 12.4 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GWT1 PF06423.7 CCF48545.1 - 1.1e-40 138.8 0.3 2.7e-40 137.6 0.2 1.7 1 0 0 1 1 1 1 GWT1 FAM176 PF14851.1 CCF48545.1 - 0.0086 15.7 0.2 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 FAM176 family Exo_endo_phos PF03372.18 CCF48546.1 - 4.9e-25 88.8 0.3 3.8e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family IF-2B PF01008.12 CCF48548.1 - 3.1e-69 233.0 0.0 3.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIID_20kDa PF03847.8 CCF48548.1 - 0.076 13.3 0.3 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Pkinase PF00069.20 CCF48549.1 - 2.4e-32 112.1 0.0 2.5e-26 92.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48549.1 - 3.6e-17 62.2 0.0 2.4e-14 53.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF48549.1 - 7.3e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCF48549.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PI3_PI4_kinase PF00454.22 CCF48550.1 - 4.1e-36 124.6 0.0 6.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CAP_GLY PF01302.20 CCF48551.1 - 6.7e-17 60.9 0.1 1.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_2 PF13696.1 CCF48551.1 - 0.81 9.2 3.4 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCF48551.1 - 9.3 6.0 7.6 10 5.8 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 CCF48552.1 - 2.3e-46 158.0 0.0 1.1e-45 155.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48552.1 - 1.5e-29 102.8 0.0 3.9e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCF48552.1 - 0.0023 17.6 0.1 0.15 11.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cellulase PF00150.13 CCF48553.1 - 0.00015 21.0 0.2 0.062 12.5 0.1 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Acyl_transf_3 PF01757.17 CCF48555.1 - 4.9e-35 120.9 26.7 4.9e-35 120.9 18.5 3.1 3 0 0 3 3 3 1 Acyltransferase family Glyco_trans_2_3 PF13632.1 CCF48555.1 - 3.7e-28 98.5 2.0 3.7e-28 98.5 1.4 3.9 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF48555.1 - 3.2e-18 66.3 0.0 6.2e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CCF48555.1 - 0.019 14.2 0.2 0.2 10.9 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferase family 21 FAD_binding_3 PF01494.14 CCF48556.1 - 1.5e-19 70.2 1.2 1.7e-12 47.0 0.0 3.4 3 1 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 CCF48556.1 - 3.3e-07 30.5 0.5 8.2e-06 26.1 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF48556.1 - 6.1e-05 22.9 0.1 0.00021 21.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF48556.1 - 0.00022 20.2 0.0 0.00043 19.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF48556.1 - 0.00053 18.5 1.0 0.002 16.6 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 CCF48556.1 - 0.0021 17.0 0.0 0.0041 16.0 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 CCF48556.1 - 0.011 14.6 0.1 0.26 10.0 0.0 2.8 3 0 0 3 3 3 0 Squalene epoxidase Pyr_redox_2 PF07992.9 CCF48556.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 CCF48556.1 - 0.014 15.3 0.0 1.7 8.6 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat FAD_oxidored PF12831.2 CCF48556.1 - 0.018 14.1 0.2 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 CCF48556.1 - 0.052 12.6 0.0 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 CCF48556.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_ligase_A_N PF04675.9 CCF48556.1 - 0.081 12.7 0.9 0.18 11.5 0.6 1.5 1 0 0 1 1 1 0 DNA ligase N terminus Glyco_hydro_45 PF02015.11 CCF48558.1 - 1.6e-80 269.8 12.2 2.9e-80 269.0 8.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 RNA_pol_Rpc34 PF05158.7 CCF48559.1 - 5.9e-80 268.9 0.9 7e-69 232.5 0.1 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.14 CCF48559.1 - 0.0027 17.3 0.1 0.0092 15.6 0.1 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 CCF48559.1 - 0.016 15.0 0.2 0.053 13.3 0.1 1.9 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF936 PF06075.7 CCF48559.1 - 0.034 13.0 26.7 0.057 12.3 18.5 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOBP PF15279.1 CCF48559.1 - 2.9 8.1 14.7 7.2 6.8 10.2 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein WD40 PF00400.27 CCF48560.1 - 9.5e-28 95.0 15.7 7.5e-08 31.9 0.0 7.1 6 1 1 7 7 7 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CCF48560.1 - 1.4e-24 86.6 0.0 2.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCF48560.1 - 3e-10 39.8 0.0 5.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 CCF48560.1 - 0.00015 20.6 5.7 0.0069 15.1 1.2 3.9 2 2 2 4 4 4 1 Nup133 N terminal like Pox_TAP PF03355.9 CCF48560.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral Trans-Activator Protein Glyoxalase PF00903.20 CCF48561.1 - 3.9e-23 81.8 0.3 5.3e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCF48561.1 - 2.3e-17 63.5 0.0 3.2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCF48561.1 - 1e-09 38.3 0.1 1.8e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CCF48561.1 - 2.9e-06 27.3 0.0 0.0066 16.3 0.0 2.1 1 1 2 3 3 3 2 Glyoxalase-like domain EAP30 PF04157.11 CCF48561.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 EAP30/Vps36 family DUF1681 PF07933.9 CCF48561.1 - 0.13 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) Glycos_transf_2 PF00535.21 CCF48562.1 - 8.9e-28 97.0 0.0 1.2e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCF48562.1 - 7.4e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCF48562.1 - 0.00067 18.8 0.0 0.00093 18.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CLASP_N PF12348.3 CCF48563.1 - 1.4e-24 86.7 0.0 1.1e-07 31.4 0.0 5.4 5 2 1 6 6 6 4 CLASP N terminal HEAT PF02985.17 CCF48563.1 - 1.6e-16 58.7 14.9 0.012 15.6 0.0 9.4 9 0 0 9 9 9 5 HEAT repeat Proteasom_PSMB PF10508.4 CCF48563.1 - 0.00049 18.5 0.0 0.27 9.4 0.0 3.0 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.2 CCF48563.1 - 0.0011 19.2 0.0 3.1 8.2 0.0 5.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCF48563.1 - 0.0013 19.1 17.7 0.63 10.6 0.0 8.6 8 0 0 8 8 8 1 HEAT-like repeat Arm PF00514.18 CCF48563.1 - 0.0013 18.5 2.3 0.96 9.3 0.1 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat NUDE_C PF04880.8 CCF48564.1 - 4e-11 43.5 13.7 4e-11 43.5 9.5 5.2 2 1 4 6 6 2 1 NUDE protein, C-terminal conserved region Filament PF00038.16 CCF48564.1 - 0.0012 18.3 8.8 0.0012 18.3 6.1 2.3 1 1 1 2 2 2 1 Intermediate filament protein TMF_DNA_bd PF12329.3 CCF48564.1 - 0.0088 15.8 3.0 0.0088 15.8 2.1 4.2 2 2 2 4 4 4 2 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CCF48564.1 - 0.023 15.0 8.2 0.023 15.0 5.7 3.7 2 1 1 3 3 2 0 Protein of unknown function (DUF904) DUF3584 PF12128.3 CCF48564.1 - 0.038 11.3 20.5 0.051 10.9 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Latarcin PF10279.4 CCF48564.1 - 0.044 13.9 7.5 1.1 9.5 0.8 3.6 1 1 1 2 2 2 0 Latarcin precursor Prefoldin_2 PF01920.15 CCF48564.1 - 0.045 13.5 25.3 2.6 7.8 9.9 4.1 2 1 1 3 3 3 0 Prefoldin subunit ERM PF00769.14 CCF48564.1 - 0.046 13.2 28.4 0.32 10.4 11.3 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family IncA PF04156.9 CCF48564.1 - 0.05 13.2 27.8 0.7 9.4 11.8 3.2 1 1 1 2 2 2 0 IncA protein TPR_MLP1_2 PF07926.7 CCF48564.1 - 0.088 12.5 29.0 0.12 12.1 4.3 3.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 CCF48564.1 - 0.13 12.3 7.7 7 6.7 0.1 3.9 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Bacillus_HBL PF05791.6 CCF48564.1 - 0.16 11.3 9.1 0.013 14.9 2.1 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 CCF48564.1 - 0.2 11.1 14.0 0.33 10.4 0.1 3.7 2 1 1 3 3 3 0 Septum formation initiator DUF1409 PF07197.7 CCF48564.1 - 0.46 10.5 6.4 0.69 10.0 0.3 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1409) Phlebovirus_NSM PF07246.6 CCF48564.1 - 0.51 9.4 10.8 1.1 8.3 1.9 2.4 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M WEMBL PF05701.6 CCF48564.1 - 0.52 8.7 31.2 0.087 11.2 19.0 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF948 PF06103.6 CCF48564.1 - 0.55 10.1 10.3 7.2 6.5 0.6 3.9 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 CCF48564.1 - 0.83 9.4 5.4 0.65 9.8 0.4 2.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 CCF48564.1 - 0.93 9.2 17.4 0.12 12.0 4.1 2.8 1 1 1 2 2 2 0 Laminin Domain II DMPK_coil PF08826.5 CCF48564.1 - 1 9.3 22.6 0.2 11.6 1.4 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like MCPsignal PF00015.16 CCF48564.1 - 1.2 8.6 10.8 0.026 14.0 1.0 2.7 2 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SlyX PF04102.7 CCF48564.1 - 1.2 9.5 15.4 2.3 8.6 0.6 5.1 3 1 2 5 5 5 0 SlyX NPV_P10 PF05531.7 CCF48564.1 - 1.5 9.1 7.0 48 4.3 2.6 3.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 CCF48564.1 - 1.6 9.2 18.8 0.39 11.1 2.6 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2225 PF09986.4 CCF48564.1 - 2.1 7.7 5.0 3.7 6.9 3.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Prominin PF05478.6 CCF48564.1 - 2.2 5.6 12.1 3.2 5.1 8.4 1.1 1 0 0 1 1 1 0 Prominin DUF3452 PF11934.3 CCF48564.1 - 2.3 7.5 5.1 1.5 8.1 1.3 2.3 2 1 0 2 2 1 0 Domain of unknown function (DUF3452) Atg14 PF10186.4 CCF48564.1 - 2.9 6.7 19.8 2.5 6.9 7.3 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 CCF48564.1 - 3.2 7.5 9.2 2.8 7.7 1.0 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper Mnd1 PF03962.10 CCF48564.1 - 7.6 6.1 24.7 3.6 7.1 8.5 2.3 1 1 1 2 2 2 0 Mnd1 family FAA_hydrolase PF01557.13 CCF48565.1 - 2.7e-45 154.4 0.0 3.5e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GST_N_3 PF13417.1 CCF48566.1 - 2.8e-11 43.4 0.0 5.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCF48566.1 - 7.6e-11 42.0 0.0 2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCF48566.1 - 3.8e-09 36.4 0.0 6.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCF48566.1 - 5.9e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF48566.1 - 4.6e-08 32.8 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF48566.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OSCP PF00213.13 CCF48567.1 - 2.7e-36 125.0 0.2 3.2e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit eIF-3c_N PF05470.7 CCF48568.1 - 1.9e-180 600.8 21.1 1.9e-180 600.8 14.7 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCF48568.1 - 1.6e-13 50.8 0.0 5.4e-13 49.1 0.0 2.0 1 0 0 1 1 1 1 PCI domain FeoC PF09012.5 CCF48568.1 - 0.028 14.1 0.7 0.074 12.7 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator DnaJ PF00226.26 CCF48569.1 - 7.1e-12 44.8 0.5 7.1e-12 44.8 0.3 2.7 3 0 0 3 3 3 1 DnaJ domain Pkinase PF00069.20 CCF48570.1 - 1.7e-10 40.5 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 CCF48570.1 - 3.1e-07 29.9 3.0 0.041 13.9 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.2 CCF48570.1 - 0.057 13.3 0.3 33 4.5 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Pkinase_Tyr PF07714.12 CCF48570.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Vac14_Fab1_bd PF12755.2 CCF48570.1 - 0.11 12.8 0.0 6.3 7.2 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Med14 PF08638.6 CCF48571.1 - 9.8e-52 175.0 0.0 2e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 MHYT PF03707.11 CCF48572.1 - 2.1e-10 40.5 23.2 6.4e-05 22.9 3.5 4.7 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Pex16 PF08610.5 CCF48574.1 - 4e-76 256.2 0.0 3.3e-72 243.3 0.0 2.7 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Pkinase PF00069.20 CCF48575.1 - 7.4e-55 185.8 0.0 9.1e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48575.1 - 1.8e-38 132.1 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF48575.1 - 1.1e-05 24.6 0.0 2.4e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCF48575.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Prominin PF05478.6 CCF48575.1 - 0.16 9.4 0.1 0.23 8.9 0.0 1.1 1 0 0 1 1 1 0 Prominin Sporozoite_P67 PF05642.6 CCF48575.1 - 4.4 5.0 11.9 7.8 4.2 8.3 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MmgE_PrpD PF03972.9 CCF48576.1 - 7.6e-150 498.9 0.0 9.6e-150 498.6 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PALP PF00291.20 CCF48577.1 - 2.3e-65 220.8 0.0 3e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3425 PF11905.3 CCF48578.1 - 1.2e-17 64.1 1.3 2.1e-17 63.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.10 CCF48578.1 - 0.015 15.1 1.9 0.024 14.4 1.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Lant_dehyd_C PF04738.8 CCF48578.1 - 0.021 13.0 0.4 0.03 12.5 0.3 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus bZIP_1 PF00170.16 CCF48578.1 - 1.3 9.0 6.7 2.6 8.0 4.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor PPR_2 PF13041.1 CCF48580.1 - 2.9e-13 49.5 0.0 4e-05 23.4 0.0 4.8 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.15 CCF48580.1 - 4.4e-07 29.4 0.0 0.91 9.6 0.0 5.7 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 CCF48580.1 - 5.6e-06 26.2 6.1 9.5 6.7 0.0 8.5 12 0 0 12 12 12 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCF48580.1 - 0.025 14.0 0.1 1.1 8.7 0.1 3.2 3 0 0 3 3 3 0 PPR repeat KH_1 PF00013.24 CCF48581.1 - 5.4e-81 266.1 33.3 7.7e-13 47.8 2.2 13.7 14 1 0 14 14 14 10 KH domain KH_3 PF13014.1 CCF48581.1 - 2.4e-50 167.4 36.1 3.5e-08 32.9 1.3 14.4 15 0 0 15 15 15 8 KH domain KH_2 PF07650.12 CCF48581.1 - 2.8e-19 68.4 22.2 0.0066 15.9 0.0 10.6 10 1 1 11 11 11 5 KH domain KH_4 PF13083.1 CCF48581.1 - 2.8e-07 30.0 21.3 0.32 10.6 0.0 8.8 7 1 2 9 9 9 4 KH domain SLS PF14611.1 CCF48581.1 - 0.00027 20.4 19.4 0.086 12.2 0.4 8.2 8 1 1 9 9 9 2 Mitochondrial inner-membrane-bound regulator DUF4112 PF13430.1 CCF48582.1 - 2.1e-28 98.3 0.9 5.1e-28 97.0 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MFS_1 PF07690.11 CCF48582.1 - 8.1e-20 70.8 54.8 6.1e-14 51.5 17.3 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 CCF48582.1 - 0.029 12.4 9.4 0.094 10.7 2.3 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family KAR9 PF08580.5 CCF48586.1 - 2.8e-07 29.2 0.0 2.8e-07 29.2 0.0 4.3 3 1 0 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.12 CCF48586.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HALZ PF02183.13 CCF48586.1 - 0.11 12.2 0.9 0.29 10.8 0.6 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper Spectrin PF00435.16 CCF48586.1 - 0.23 11.7 4.2 5.5 7.3 0.1 3.3 3 0 0 3 3 3 0 Spectrin repeat YgaB PF14182.1 CCF48586.1 - 0.27 11.4 1.5 22 5.3 0.0 3.5 3 0 0 3 3 3 0 YgaB-like protein TBPIP PF07106.8 CCF48586.1 - 0.28 10.7 0.6 29 4.1 0.0 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ribosomal_L27 PF01016.14 CCF48587.1 - 5.6e-32 109.3 0.1 8.8e-32 108.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Neuregulin PF02158.10 CCF48587.1 - 0.023 13.4 1.4 0.032 13.0 0.9 1.2 1 0 0 1 1 1 0 Neuregulin family OEP PF02321.13 CCF48587.1 - 0.12 11.9 0.5 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Outer membrane efflux protein Tim17 PF02466.14 CCF48588.1 - 2.2e-25 89.1 6.4 3e-25 88.7 4.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PTP_N PF12453.3 CCF48588.1 - 2.1 8.0 5.2 0.35 10.5 0.7 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase N terminal Fungal_trans PF04082.13 CCF48589.1 - 7.7e-15 54.4 0.0 1.5e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF48589.1 - 0.00016 21.4 11.1 0.00031 20.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHF5 PF03660.9 CCF48590.1 - 8.5e-48 160.8 7.5 9.9e-48 160.6 5.2 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 CCF48590.1 - 0.061 13.0 2.1 0.061 13.0 1.5 2.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DZR PF12773.2 CCF48590.1 - 0.17 11.7 9.6 6 6.7 6.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 CCF48590.1 - 0.3 10.8 11.3 2.6 7.8 0.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 CCF48590.1 - 0.9 9.2 7.9 1.7 8.3 4.7 2.3 2 1 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 CCF48590.1 - 1.5 8.5 12.1 2.8 7.6 0.3 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF48590.1 - 3.2 7.8 11.4 10 6.2 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 CCF48590.1 - 3.5 7.4 9.3 60 3.5 5.3 2.3 1 1 1 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 CCF48590.1 - 3.5 7.0 13.2 1.6 8.1 1.6 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding DUF2039 PF10217.4 CCF48590.1 - 8.3 6.5 9.3 1 9.4 1.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) ELMO_CED12 PF04727.8 CCF48591.1 - 8e-35 119.8 0.0 1.2e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 CCF48591.1 - 1.6e-09 37.6 0.0 1.1e-07 31.7 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.9 CCF48591.1 - 0.0021 17.2 0.1 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 V-ATPase subunit H Coq4 PF05019.8 CCF48592.1 - 6.3e-60 201.8 0.0 5.1e-49 166.1 0.0 2.1 1 1 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Glyco_transf_21 PF13506.1 CCF48593.1 - 1.5e-18 66.6 0.2 2.1e-07 30.3 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 CCF48593.1 - 3e-10 40.2 0.0 2.4e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Lyase_1 PF00206.15 CCF48594.1 - 8.4e-96 320.8 0.0 1.3e-95 320.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CCF48594.1 - 2.6e-28 97.8 0.0 5.3e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Phage_term_smal PF05944.7 CCF48594.1 - 0.11 12.1 0.0 9.2 5.9 0.0 2.6 2 0 0 2 2 2 0 Phage small terminase subunit Methyltransf_31 PF13847.1 CCF48597.1 - 5e-26 91.1 0.0 1.3e-24 86.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF48597.1 - 2.7e-24 85.4 0.0 5.9e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF48597.1 - 1.5e-18 67.4 0.1 8.6e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF48597.1 - 1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF48597.1 - 3.2e-16 59.6 0.0 5.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF48597.1 - 2.1e-14 53.7 0.0 7.5e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF48597.1 - 4.8e-13 48.7 0.0 8.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCF48597.1 - 1.4e-09 37.9 0.2 6.5e-09 35.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCF48597.1 - 1.9e-08 33.8 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CCF48597.1 - 8.3e-07 28.7 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CCF48597.1 - 8.5e-07 28.2 0.0 2.5e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 CCF48597.1 - 0.00035 19.9 0.0 0.0066 15.8 0.0 2.1 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 CCF48597.1 - 0.00053 19.1 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 CCF48597.1 - 0.00072 18.5 0.0 0.0048 15.8 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_29 PF03141.11 CCF48597.1 - 0.00092 17.6 1.0 0.0018 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.6 CCF48597.1 - 0.00096 17.9 0.0 0.0023 16.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 CCF48597.1 - 0.0015 18.1 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCF48597.1 - 0.0048 15.9 0.1 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 CCF48597.1 - 0.0074 15.9 0.0 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase CheR PF01739.13 CCF48597.1 - 0.0083 15.4 0.0 0.71 9.1 0.0 2.2 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Prok-E2_E PF14462.1 CCF48597.1 - 0.019 14.5 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family E NAD_binding_10 PF13460.1 CCF48597.1 - 0.043 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NodS PF05401.6 CCF48597.1 - 0.045 13.1 0.0 0.094 12.1 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) FtsJ PF01728.14 CCF48597.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1772 PF08592.6 CCF48598.1 - 1.2e-28 99.6 4.4 1.5e-28 99.2 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) FMN_dh PF01070.13 CCF48602.1 - 1.8e-113 379.0 0.0 2.2e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CCF48602.1 - 0.00013 21.0 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCF48602.1 - 0.00018 20.5 0.2 0.00043 19.2 0.1 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCF48602.1 - 0.0082 15.2 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 CCF48602.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Amidase PF01425.16 CCF48603.1 - 9.2e-102 341.1 3.8 3e-101 339.4 2.6 1.7 1 1 0 1 1 1 1 Amidase Response_reg PF00072.19 CCF48605.1 - 1.1e-15 57.5 0.0 2.6e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Tropomyosin_1 PF12718.2 CCF48606.1 - 9.7e-46 155.1 31.0 1.1e-45 154.9 21.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CCF48606.1 - 1.3e-11 44.0 30.2 4.1e-05 22.7 4.2 2.9 1 1 2 3 3 3 3 Tropomyosin CENP-F_leu_zip PF10473.4 CCF48606.1 - 1.5e-06 28.1 30.1 4.9e-05 23.2 5.8 2.9 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.3 CCF48606.1 - 1.8e-05 24.1 21.3 0.00076 18.8 6.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) GAS PF13851.1 CCF48606.1 - 0.00013 21.1 27.9 0.00024 20.3 19.3 1.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CCF48606.1 - 0.00033 20.4 29.9 0.002 17.9 4.8 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 CCF48606.1 - 0.0008 19.3 14.7 0.0017 18.2 2.0 2.8 1 1 2 3 3 3 1 FlxA-like protein Myosin_tail_1 PF01576.14 CCF48606.1 - 0.0028 15.4 31.4 0.0034 15.2 21.8 1.0 1 0 0 1 1 1 1 Myosin tail ERM PF00769.14 CCF48606.1 - 0.0041 16.7 26.9 0.0041 16.7 18.7 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family FliD_C PF07195.7 CCF48606.1 - 0.0056 16.0 13.9 0.015 14.6 0.3 2.9 1 1 2 3 3 3 1 Flagellar hook-associated protein 2 C-terminus APG6 PF04111.7 CCF48606.1 - 0.0075 15.3 29.6 0.039 12.9 11.7 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CCF48606.1 - 0.012 14.8 6.3 0.077 12.1 0.6 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CCF48606.1 - 0.013 15.1 26.6 0.0088 15.6 13.8 2.0 1 1 1 2 2 2 0 IncA protein ADIP PF11559.3 CCF48606.1 - 0.013 15.3 27.4 0.47 10.3 0.9 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TelA PF05816.6 CCF48606.1 - 0.022 13.4 13.0 0.027 13.1 1.8 2.0 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) DUF3584 PF12128.3 CCF48606.1 - 0.027 11.8 25.6 0.026 11.8 8.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 CCF48606.1 - 0.034 14.2 12.8 1.4 9.0 0.2 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3287 PF11690.3 CCF48606.1 - 0.039 14.0 11.5 0.071 13.1 0.5 3.3 1 1 3 4 4 3 0 Protein of unknown function (DUF3287) DUF4200 PF13863.1 CCF48606.1 - 0.04 13.8 27.0 0.15 12.0 4.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Rota_NSP3 PF01665.11 CCF48606.1 - 0.043 12.7 4.7 0.063 12.2 0.8 1.9 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 ATG16 PF08614.6 CCF48606.1 - 0.044 13.6 24.7 0.38 10.5 5.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CCF48606.1 - 0.046 12.1 18.7 0.05 12.0 13.0 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 CCF48606.1 - 0.05 12.2 24.2 0.026 13.2 13.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.1 CCF48606.1 - 0.068 13.6 23.6 0.16 12.4 3.2 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 CCF48606.1 - 0.07 12.0 18.3 0.22 10.4 12.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF869 PF05911.6 CCF48606.1 - 0.092 10.9 24.0 0.027 12.7 3.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Mod_r PF07200.8 CCF48606.1 - 0.096 12.6 22.5 0.078 12.9 10.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF948 PF06103.6 CCF48606.1 - 0.11 12.3 8.0 1.9 8.3 0.6 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.3 CCF48606.1 - 0.11 11.8 19.9 0.18 11.1 6.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Snapin_Pallidin PF14712.1 CCF48606.1 - 0.11 12.7 14.5 0.29 11.4 2.4 2.5 1 1 1 2 2 2 0 Snapin/Pallidin DUF812 PF05667.6 CCF48606.1 - 0.15 10.5 24.2 0.33 9.4 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_27 PF13514.1 CCF48606.1 - 0.15 9.6 28.5 0.041 11.5 10.5 2.0 1 1 1 2 2 2 0 AAA domain EzrA PF06160.7 CCF48606.1 - 0.19 9.9 21.0 0.082 11.0 5.8 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Filament PF00038.16 CCF48606.1 - 0.19 11.1 24.5 0.42 10.0 17.0 1.5 1 1 0 1 1 1 0 Intermediate filament protein BLOC1_2 PF10046.4 CCF48606.1 - 0.22 11.6 16.3 2.1 8.5 3.6 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF641 PF04859.7 CCF48606.1 - 0.23 11.2 15.9 0.18 11.5 1.2 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.6 CCF48606.1 - 0.23 10.8 22.0 1.6 8.1 9.1 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Laminin_II PF06009.7 CCF48606.1 - 0.23 11.1 15.3 0.11 12.3 3.5 2.2 1 1 1 2 2 2 0 Laminin Domain II SlyX PF04102.7 CCF48606.1 - 0.24 11.8 17.4 1.5 9.2 1.0 3.6 2 2 2 4 4 3 0 SlyX Atg14 PF10186.4 CCF48606.1 - 0.27 10.1 23.0 0.22 10.4 11.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 CCF48606.1 - 0.27 11.2 25.0 2.2 8.2 10.9 2.9 1 1 1 2 2 2 0 Up-regulated During Septation bZIP_1 PF00170.16 CCF48606.1 - 0.29 11.0 21.4 0.36 10.8 2.3 3.9 2 2 1 3 3 3 0 bZIP transcription factor CCDC144C PF14915.1 CCF48606.1 - 0.33 9.8 24.7 12 4.6 17.1 2.1 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region Borrelia_P83 PF05262.6 CCF48606.1 - 0.34 9.1 22.3 0.38 8.9 15.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3552 PF12072.3 CCF48606.1 - 0.38 9.9 27.4 2.6 7.2 10.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TPR_MLP1_2 PF07926.7 CCF48606.1 - 0.41 10.3 29.1 35 4.1 20.2 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.1 CCF48606.1 - 0.42 10.0 23.3 36 3.7 10.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-Q PF13094.1 CCF48606.1 - 0.43 10.6 29.2 5.2 7.0 7.5 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cluap1 PF10234.4 CCF48606.1 - 0.44 9.7 20.8 0.28 10.3 5.2 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Prefoldin_2 PF01920.15 CCF48606.1 - 0.45 10.2 26.8 0.32 10.7 1.9 3.9 1 1 3 4 4 4 0 Prefoldin subunit PspA_IM30 PF04012.7 CCF48606.1 - 0.53 9.6 27.6 8.8 5.6 18.9 2.6 1 1 0 1 1 1 0 PspA/IM30 family NPV_P10 PF05531.7 CCF48606.1 - 0.56 10.4 9.8 1.5 9.0 0.7 3.4 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CCF48606.1 - 0.57 9.9 11.4 0.45 10.3 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.8 CCF48606.1 - 0.63 10.4 14.5 9.6 6.6 2.3 3.9 1 1 2 3 3 3 0 Histidine kinase RmuC PF02646.11 CCF48606.1 - 0.68 8.7 13.3 0.78 8.5 1.4 2.3 1 1 0 2 2 2 0 RmuC family BBP1_N PF15271.1 CCF48606.1 - 0.69 10.2 5.7 0.54 10.6 3.0 1.5 1 1 1 2 2 1 0 Spindle pole body component BBP1, Mps2-binding protein WXG100 PF06013.7 CCF48606.1 - 0.81 9.7 11.5 13 5.8 0.7 3.5 2 1 2 4 4 4 0 Proteins of 100 residues with WXG YlqD PF11068.3 CCF48606.1 - 1 9.4 19.1 0.59 10.1 5.0 2.8 1 1 2 3 3 3 0 YlqD protein Mnd1 PF03962.10 CCF48606.1 - 1.2 8.7 24.3 2.3 7.8 10.7 2.7 1 1 1 2 2 2 0 Mnd1 family CALCOCO1 PF07888.6 CCF48606.1 - 1.3 7.2 22.2 1.8 6.7 15.4 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nup54 PF13874.1 CCF48606.1 - 1.4 8.6 18.2 1 9.0 2.6 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 CENP-K PF11802.3 CCF48606.1 - 1.4 8.0 12.8 0.074 12.2 1.7 2.0 1 1 1 2 2 2 0 Centromere-associated protein K DUF4559 PF15112.1 CCF48606.1 - 1.7 7.7 13.6 3.2 6.8 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) GrpE PF01025.14 CCF48606.1 - 1.9 8.0 25.1 20 4.6 4.0 3.0 1 1 1 2 2 2 0 GrpE CCDC155 PF14662.1 CCF48606.1 - 2.1 7.9 28.7 3.2 7.3 15.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 LRS4 PF10422.4 CCF48606.1 - 2.2 7.5 15.2 2.9 7.1 10.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 TMCO5 PF14992.1 CCF48606.1 - 2.3 7.3 23.9 7.6 5.5 14.5 2.4 1 1 1 2 2 2 0 TMCO5 family TMF_TATA_bd PF12325.3 CCF48606.1 - 2.3 7.9 26.8 4.1 7.1 11.4 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Lectin_N PF03954.9 CCF48606.1 - 2.3 7.5 8.4 4.6 6.6 4.7 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.17 CCF48606.1 - 2.6 8.1 23.2 5.2 7.1 0.5 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 CCF48606.1 - 2.6 7.6 21.6 8.2 5.9 8.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) EHN PF06441.7 CCF48606.1 - 2.7 7.9 8.8 7 6.6 2.0 2.6 1 1 2 3 3 3 0 Epoxide hydrolase N terminus IFT57 PF10498.4 CCF48606.1 - 2.8 6.6 19.3 2.4 6.8 4.8 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF919 PF06034.6 CCF48606.1 - 2.8 7.6 9.6 1.5 8.4 0.8 3.2 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Prefoldin PF02996.12 CCF48606.1 - 2.9 7.5 23.3 0.96 9.1 2.0 4.0 1 1 3 4 4 4 0 Prefoldin subunit Cortex-I_coil PF09304.5 CCF48606.1 - 3.1 7.8 27.1 0.79 9.7 6.0 3.0 1 1 0 2 2 2 0 Cortexillin I, coiled coil FemAB PF02388.11 CCF48606.1 - 3.3 6.3 16.2 0.3 9.7 3.0 2.1 1 1 1 2 2 2 0 FemAB family Med9 PF07544.8 CCF48606.1 - 3.7 7.3 14.7 3.8 7.3 2.4 2.9 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Vac_Fusion PF02346.11 CCF48606.1 - 4.3 6.8 7.3 4.3 6.8 0.1 3.0 2 1 1 3 3 3 0 Chordopoxvirus fusion protein Tup_N PF08581.5 CCF48606.1 - 4.7 7.4 18.9 0.56 10.4 1.6 3.0 1 1 1 2 2 2 0 Tup N-terminal AHS1 PF02682.11 CCF48606.1 - 5.5 6.3 7.6 3.2 7.1 1.8 2.0 1 1 1 2 2 2 0 Allophanate hydrolase subunit 1 Fzo_mitofusin PF04799.8 CCF48606.1 - 5.7 6.2 12.3 0.96 8.8 2.5 2.4 1 1 1 2 2 2 0 fzo-like conserved region Med4 PF10018.4 CCF48606.1 - 6.1 6.2 20.8 8.6 5.7 5.5 2.9 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Ax_dynein_light PF10211.4 CCF48606.1 - 7.4 6.3 23.6 4.9 6.9 6.2 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain Hormone_1 PF00103.15 CCF48606.1 - 7.4 5.8 8.8 5 6.3 0.6 2.1 1 1 1 2 2 2 0 Somatotropin hormone family Jnk-SapK_ap_N PF09744.4 CCF48606.1 - 7.7 6.4 25.4 1.8 8.5 12.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Microtub_assoc PF07989.6 CCF48606.1 - 8.3 6.3 16.0 15 5.5 1.5 3.3 2 1 1 3 3 3 0 Microtubule associated V_ATPase_I PF01496.14 CCF48606.1 - 8.3 4.1 18.3 19 2.9 12.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD PF00529.15 CCF48606.1 - 8.4 5.6 19.4 13 4.9 13.5 1.3 1 1 0 1 1 1 0 HlyD family secretion protein Syntaxin-6_N PF09177.6 CCF48606.1 - 8.5 6.8 18.3 6.8 7.1 6.0 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spectrin PF00435.16 CCF48606.1 - 8.7 6.6 23.3 6.3 7.1 9.0 3.2 1 1 1 2 2 2 0 Spectrin repeat bZIP_2 PF07716.10 CCF48606.1 - 9.3 6.1 20.4 1.8 8.4 2.5 3.9 2 2 1 3 3 3 0 Basic region leucine zipper DUF972 PF06156.8 CCF48606.1 - 9.8 6.5 20.9 1.5e+04 -5.3 14.5 2.3 1 1 0 1 1 0 0 Protein of unknown function (DUF972) Kinesin PF00225.18 CCF48607.1 - 3.8e-96 321.7 0.1 3.8e-96 321.7 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DMPK_coil PF08826.5 CCF48607.1 - 0.0016 18.2 0.9 0.0016 18.2 0.6 4.0 4 1 1 5 5 5 2 DMPK coiled coil domain like AAA_24 PF13479.1 CCF48607.1 - 0.003 17.1 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain UpxZ PF06603.6 CCF48607.1 - 0.006 16.5 0.0 0.2 11.7 0.0 2.8 2 0 0 2 2 2 1 UpxZ family of transcription anti-terminator antagonists Reo_sigmaC PF04582.7 CCF48607.1 - 0.0081 15.3 9.3 0.01 15.0 0.7 2.6 2 0 0 2 2 2 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 CCF48607.1 - 0.32 11.1 3.7 0.96 9.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF3527 PF12043.3 CCF48607.1 - 6.6 6.1 12.8 1.1 8.6 6.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) GAS PF13851.1 CCF48607.1 - 6.6 5.8 26.8 0.017 14.3 3.2 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding TRAUB PF08164.7 CCF48608.1 - 1.4e-25 89.2 3.6 7e-25 86.9 0.0 2.9 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CCF48608.1 - 8.6e-19 67.9 1.3 8.6e-19 67.9 0.9 3.3 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor Nsp1_C PF05064.8 CCF48609.1 - 7.6e-28 96.5 0.0 1.5e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CCF48609.1 - 0.00012 22.2 185.2 0.18 12.0 28.5 6.3 1 1 3 4 4 4 3 Nucleoporin FG repeat region Ribosomal_L2_C PF03947.13 CCF48611.1 - 1.2e-45 154.4 5.4 1.4e-45 154.2 1.3 2.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCF48611.1 - 4.6e-26 90.5 0.4 1.3e-25 89.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain DnaJ PF00226.26 CCF48612.1 - 2.6e-20 71.8 1.4 4.7e-20 71.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain EF1G PF00647.14 CCF48612.1 - 0.074 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain GlutR_dimer PF00745.15 CCF48612.1 - 0.15 12.0 2.9 6.4 6.7 0.0 3.5 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4407 PF14362.1 CCF48612.1 - 4.7 6.0 10.7 12 4.7 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_transf_22 PF03901.12 CCF48613.1 - 3.9e-36 124.9 21.8 1.7e-28 99.8 7.2 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Cnd1_N PF12922.2 CCF48615.1 - 0.048 13.2 0.4 0.048 13.2 0.3 1.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Gastrin PF00918.12 CCF48615.1 - 0.27 12.0 1.2 0.43 11.4 0.2 1.8 1 1 1 2 2 2 0 Gastrin/cholecystokinin family PAP1 PF08601.5 CCF48615.1 - 0.28 10.8 24.1 0.34 10.5 16.7 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 SpoIIIAH PF12685.2 CCF48615.1 - 0.77 9.2 7.3 1.1 8.7 5.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SOG2 PF10428.4 CCF48615.1 - 2.6 6.5 22.8 3 6.3 15.8 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1628 PF07790.6 CCF48615.1 - 2.7 8.8 7.8 32 5.3 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) TPR_11 PF13414.1 CCF48616.1 - 2.3e-15 55.9 0.6 3.4e-09 36.1 0.0 5.0 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 CCF48616.1 - 2.3e-09 36.4 2.5 9e-05 21.9 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCF48616.1 - 2.2e-08 33.3 11.1 1.2e-05 24.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCF48616.1 - 1.5e-06 27.9 0.3 0.00095 18.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCF48616.1 - 8.1e-06 25.6 1.0 0.63 10.3 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF48616.1 - 3.4e-05 23.3 2.8 0.0092 15.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCF48616.1 - 4.3e-05 23.5 1.3 0.0002 21.4 0.3 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCF48616.1 - 0.00011 21.7 0.7 0.0036 16.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCF48616.1 - 0.0006 19.6 8.7 0.011 15.6 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48616.1 - 0.00077 19.7 2.4 0.12 12.7 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCF48616.1 - 0.061 13.8 1.7 13 6.5 0.0 5.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCF48616.1 - 0.19 12.4 19.3 0.21 12.2 0.4 5.5 6 1 0 7 7 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF48616.1 - 1 10.1 0.0 1 10.1 0.0 7.4 9 1 1 10 10 6 0 Tetratricopeptide repeat DUF3835 PF12927.2 CCF48617.1 - 0.00062 20.6 1.7 0.00062 20.6 1.2 6.3 7 2 0 7 7 7 2 Domain of unknown function (DUF3835) HECT PF00632.20 CCF48618.1 - 4.4e-77 259.3 0.0 6.5e-77 258.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 CCF48618.1 - 2.5 6.3 4.8 0.78 7.9 0.1 2.2 3 0 0 3 3 3 0 Adaptin N terminal region DEAD PF00270.24 CCF48619.1 - 7.5e-46 155.7 0.0 1.6e-45 154.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCF48619.1 - 5.3e-23 80.3 0.7 1.2e-22 79.2 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCF48619.1 - 2.2e-22 78.7 0.0 6.1e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3371 PF11851.3 CCF48620.1 - 0.025 15.2 0.0 0.086 13.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TPR_14 PF13428.1 CCF48620.1 - 1.2 9.9 10.4 0.21 12.3 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Chorion_2 PF03964.10 CCF48620.1 - 9.2 6.8 8.0 11 6.6 1.5 2.5 2 0 0 2 2 2 0 Chorion family 2 Rad21_Rec8_N PF04825.8 CCF48621.1 - 0.0016 18.3 0.1 0.0045 16.9 0.1 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Cupin_8 PF13621.1 CCF48622.1 - 2.3e-09 37.1 0.0 8.9e-09 35.2 0.0 1.9 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.17 CCF48622.1 - 4.8e-06 26.8 0.1 0.00016 21.8 0.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CCF48622.1 - 3.4e-05 23.4 13.7 7.8e-05 22.2 9.5 1.6 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF48622.1 - 4.6 6.6 15.2 0.51 9.6 7.5 1.8 2 0 0 2 2 2 0 PHD-finger Ammonium_transp PF00909.16 CCF48623.1 - 1.7e-105 352.7 29.0 2e-105 352.5 20.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family UIM PF02809.15 CCF48624.1 - 1 9.1 3.7 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Kinesin PF00225.18 CCF48625.1 - 2.1e-97 325.8 0.0 3.1e-97 325.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TMF_DNA_bd PF12329.3 CCF48625.1 - 0.5 10.2 9.4 0.085 12.6 0.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2015 PF09435.5 CCF48626.1 - 5.1e-30 103.8 0.2 1.5e-29 102.3 0.0 1.7 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF2015) DNA_pol_B PF00136.16 CCF48628.1 - 1.9e-113 379.7 0.1 2.7e-113 379.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCF48628.1 - 8.1e-62 207.9 0.0 1.3e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CCF48628.1 - 5e-28 97.9 0.0 8.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CCF48628.1 - 1.4e-19 69.6 4.2 1.4e-19 69.6 2.9 2.7 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal Nop14 PF04147.7 CCF48628.1 - 1.1 7.1 10.4 1.7 6.4 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.22 CCF48629.1 - 2.3e-28 97.7 3.5 3.5e-16 58.6 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein PRKCSH PF07915.8 CCF48630.1 - 3.1e-13 50.3 1.2 1.5e-09 38.5 0.0 3.4 3 0 0 3 3 3 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 CCF48630.1 - 0.077 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PX PF00787.19 CCF48631.1 - 1.2e-20 73.3 0.0 2.6e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CCF48631.1 - 1.9e-05 24.0 10.0 0.0015 17.8 0.8 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.4 CCF48631.1 - 0.058 12.6 1.3 0.094 11.9 0.1 1.8 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DASH_Hsk3 PF08227.6 CCF48631.1 - 1.3 9.2 3.8 0.93 9.7 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like FAD_binding_4 PF01565.18 CCF48635.1 - 3.6e-22 78.3 0.4 6.6e-22 77.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Exo5 PF09810.4 CCF48637.1 - 2.2e-43 148.7 0.0 3.3e-40 138.2 0.0 2.7 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease GPI2 PF06432.6 CCF48638.1 - 5.5e-66 222.7 8.4 8.3e-66 222.1 5.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Tmemb_cc2 PF10267.4 CCF48639.1 - 0.065 11.8 0.3 0.1 11.1 0.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MFS_1 PF07690.11 CCF48640.1 - 4e-29 101.4 21.3 1.6e-26 92.8 16.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_kinase PF01513.16 CCF48641.1 - 2.3e-53 180.8 0.0 3.2e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF3386 PF11866.3 CCF48641.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) DUF1014 PF06244.7 CCF48642.1 - 1.9e-27 95.8 11.7 1.5e-26 92.9 8.1 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF2852 PF11014.3 CCF48642.1 - 0.77 9.7 10.0 0.05 13.5 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) Rhodanese PF00581.15 CCF48643.1 - 4.5e-19 68.8 0.0 7.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain UQ_con PF00179.21 CCF48644.1 - 1.1e-46 157.6 0.0 1.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF48644.1 - 0.00067 19.4 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCF48644.1 - 0.06 13.2 0.8 0.074 12.9 0.5 1.5 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.20 CCF48645.1 - 5.6e-58 196.1 0.3 8.2e-58 195.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48645.1 - 5.2e-21 74.8 0.0 8.8e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCF48645.1 - 0.0075 15.1 0.1 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CCF48645.1 - 0.071 12.4 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DUF3967 PF13152.1 CCF48646.1 - 0.31 10.7 0.1 0.31 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3967) CLASP_N PF12348.3 CCF48647.1 - 6.7e-69 231.7 3.7 7.3e-32 110.5 0.0 4.5 3 1 1 4 4 4 4 CLASP N terminal HEAT PF02985.17 CCF48647.1 - 6.7e-05 22.6 1.2 0.087 12.9 0.1 4.4 4 0 0 4 4 4 2 HEAT repeat CTNNBL PF08216.6 CCF48647.1 - 0.034 13.7 0.1 0.087 12.4 0.1 1.7 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear UPF0029 PF01205.14 CCF48648.1 - 6.1e-16 58.0 3.2 2.3e-15 56.2 0.0 3.2 3 1 0 3 3 3 1 Uncharacterized protein family UPF0029 Dimerisation PF08100.6 CCF48648.1 - 0.17 11.7 0.6 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain AAA PF00004.24 CCF48649.1 - 7.3e-41 139.4 0.0 1.4e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF48649.1 - 9.9e-05 22.3 0.1 0.0074 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CCF48649.1 - 0.00027 20.9 0.5 0.0034 17.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCF48649.1 - 0.00037 20.2 0.2 0.0045 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCF48649.1 - 0.00039 20.5 0.4 0.017 15.2 0.3 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 CCF48649.1 - 0.00065 18.9 0.7 0.0092 15.2 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein RuvB_N PF05496.7 CCF48649.1 - 0.00094 18.2 0.0 0.002 17.2 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCF48649.1 - 0.0017 19.1 0.1 0.006 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCF48649.1 - 0.007 15.7 1.1 0.13 11.6 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CCF48649.1 - 0.01 15.5 0.1 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CCF48649.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CCF48649.1 - 0.012 14.7 0.1 0.043 12.9 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCF48649.1 - 0.012 15.4 0.0 0.052 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CCF48649.1 - 0.018 14.4 0.1 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 CCF48649.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 CCF48649.1 - 0.035 13.6 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCF48649.1 - 0.064 12.8 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCF48649.1 - 0.1 11.6 0.3 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 KaiC RPN7 PF10602.4 CCF48650.1 - 1e-51 174.8 0.0 2.2e-51 173.7 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CCF48650.1 - 1e-12 48.2 0.1 4.1e-12 46.3 0.0 2.0 2 0 0 2 2 1 1 PCI domain TPR_2 PF07719.12 CCF48650.1 - 0.00058 19.5 1.1 0.059 13.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF48650.1 - 0.0031 17.1 0.0 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CCF48650.1 - 0.0079 16.1 0.2 0.085 12.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCF48650.1 - 0.025 15.2 1.7 6.7 7.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48650.1 - 0.034 14.4 0.2 1.1 9.6 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF48650.1 - 0.052 14.2 0.3 8.6 7.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCF48650.1 - 0.058 13.8 5.4 4 8.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF48650.1 - 0.091 12.6 0.1 3.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF48650.1 - 0.12 11.9 0.2 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_PH PF01138.16 CCF48651.1 - 2.8e-33 115.0 0.0 4.7e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MS_channel PF00924.13 CCF48652.1 - 3.8e-20 72.1 0.5 5.7e-20 71.5 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CCF48652.1 - 0.00022 20.3 0.2 0.00048 19.2 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CCF48652.1 - 0.0028 16.9 0.2 0.0062 15.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CCF48652.1 - 0.0035 17.0 0.1 0.0098 15.7 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CCF48652.1 - 0.02 14.9 0.1 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 CCF48652.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Cyclin_N PF00134.18 CCF48653.1 - 3.6e-10 39.4 0.1 3.9e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 CCF48653.1 - 0.013 15.3 0.0 0.66 9.8 0.0 2.8 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Bax1-I PF01027.15 CCF48654.1 - 9.4e-33 113.5 9.0 9.4e-33 113.5 6.2 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 HEAT_EZ PF13513.1 CCF48655.1 - 2.7e-33 113.6 6.3 2.6e-05 24.5 0.0 12.0 11 0 0 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 CCF48655.1 - 5.6e-25 87.4 11.6 5.4e-05 23.3 0.0 8.7 5 4 4 9 9 9 7 HEAT repeats HEAT PF02985.17 CCF48655.1 - 3.3e-18 64.0 14.8 0.0041 17.0 0.1 11.4 13 0 0 13 13 13 3 HEAT repeat UME PF08064.8 CCF48655.1 - 4.1e-11 42.7 0.1 0.0011 18.9 0.0 6.1 4 2 1 5 5 5 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 CCF48655.1 - 7.2e-10 39.1 0.0 0.0083 16.4 0.0 6.0 7 0 0 7 7 6 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CCF48655.1 - 8.4e-10 38.5 0.7 0.0094 15.9 0.0 6.3 6 1 1 7 7 7 2 Rix1 complex component involved in 60S ribosome maturation IBN_N PF03810.14 CCF48655.1 - 2.6e-08 33.6 0.1 1.3e-07 31.4 0.0 2.4 2 0 0 2 2 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CCF48655.1 - 2.6e-08 32.6 4.4 0.015 13.6 0.0 4.3 3 1 0 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 CCF48655.1 - 8e-08 31.9 0.0 0.18 11.1 0.0 5.2 4 1 1 5 5 5 2 CLASP N terminal Xpo1 PF08389.7 CCF48655.1 - 3.6e-06 26.9 7.7 0.03 14.2 0.1 6.5 6 1 0 6 6 6 1 Exportin 1-like protein Cohesin_HEAT PF12765.2 CCF48655.1 - 1.6e-05 24.7 1.1 0.0082 16.0 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 CCF48655.1 - 0.00055 19.5 0.1 0.025 14.2 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Cnd1 PF12717.2 CCF48655.1 - 0.00064 19.6 0.0 1 9.1 0.0 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 CCF48655.1 - 0.00074 18.3 4.2 6.2 5.4 0.2 6.4 6 2 1 8 8 8 1 RNAPII transcription regulator C-terminal Cnd3 PF12719.2 CCF48655.1 - 0.01 14.8 0.9 0.42 9.5 0.1 3.8 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 CCF48655.1 - 0.013 15.3 0.6 13 5.7 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Ric8 PF10165.4 CCF48655.1 - 0.085 11.6 0.4 0.63 8.7 0.0 2.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor synembryn DUF2454 PF10521.4 CCF48655.1 - 0.14 11.0 0.1 17 4.3 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2454) Arm PF00514.18 CCF48655.1 - 2.5 8.0 11.7 92 3.0 0.0 7.1 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat Myosin_head PF00063.16 CCF48656.1 - 7.3e-243 807.6 0.4 1.3e-242 806.7 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CCF48656.1 - 3.5e-35 120.0 1.6 1.2e-34 118.2 1.1 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 CCF48656.1 - 1e-18 65.0 32.2 8.6e-05 21.8 0.1 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 CCF48656.1 - 0.011 15.9 0.0 0.052 13.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 CCF48656.1 - 0.079 12.7 19.4 0.043 13.6 3.0 3.1 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 CCF48656.1 - 0.39 10.5 9.2 0.37 10.6 2.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF972 PF06156.8 CCF48656.1 - 3.6 7.9 10.5 17 5.8 2.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ubiquitin PF00240.18 CCF48657.1 - 6.1e-70 230.5 5.9 1.4e-34 117.2 0.3 2.2 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CCF48657.1 - 3.5e-40 135.5 5.8 1e-19 69.9 0.3 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCF48657.1 - 5.3e-13 49.0 1.1 4.7e-05 23.5 0.0 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCF48657.1 - 6.1e-10 39.0 0.0 0.00081 19.1 0.0 2.2 2 0 0 2 2 2 2 Telomere stability and silencing zf-AN1 PF01428.11 CCF48657.1 - 1.4e-09 37.6 5.8 1.4e-09 37.6 4.0 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD_2 PF13881.1 CCF48657.1 - 3.2e-07 30.2 0.2 0.031 14.1 0.0 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCF48657.1 - 2.6e-06 27.5 0.2 0.038 14.1 0.0 2.3 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCF48657.1 - 0.0001 22.2 0.0 0.8 9.7 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CCF48657.1 - 0.0004 20.2 0.3 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CCF48657.1 - 0.00069 19.3 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 FlgD Ig-like domain Methyltrans_RNA PF04452.9 CCF48657.1 - 0.0028 16.7 0.3 0.65 9.0 0.0 2.6 2 1 0 3 3 3 1 RNA methyltransferase Plexin_cytopl PF08337.7 CCF48657.1 - 0.012 13.9 1.8 2.5 6.2 0.2 3.3 3 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 CCF48657.1 - 0.077 12.8 3.0 0.13 12.1 2.1 1.3 1 0 0 1 1 1 0 IBR domain USP7_C2 PF14533.1 CCF48657.1 - 0.087 12.2 0.2 7.7 5.8 0.0 2.1 1 1 0 2 2 2 0 Ubiquitin-specific protease C-terminal FERM_N PF09379.5 CCF48657.1 - 0.17 11.9 1.1 42 4.2 0.1 3.6 3 2 0 3 3 3 0 FERM N-terminal domain DUF2207 PF09972.4 CCF48657.1 - 0.25 9.8 2.4 7.1 5.0 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Tash_PEST PF07708.6 CCF48657.1 - 2.3 8.2 7.5 2.5 8.1 1.2 2.3 2 0 0 2 2 2 0 Tash protein PEST motif HsbA PF12296.3 CCF48658.1 - 1e-23 83.5 11.5 1e-23 83.5 7.9 1.5 1 1 1 2 2 2 1 Hydrophobic surface binding protein A TBPIP PF07106.8 CCF48658.1 - 0.026 14.0 0.2 1.2 8.6 0.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CCF48658.1 - 0.46 10.7 7.9 8 6.7 3.1 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein SMC_Nse1 PF07574.8 CCF48659.1 - 3.1e-22 79.1 1.5 7.7e-20 71.3 1.1 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCF48659.1 - 1.9e-05 24.5 5.0 1.9e-05 24.5 3.5 2.0 2 0 0 2 2 2 1 RING-like domain zf-HC5HC2H PF13771.1 CCF48659.1 - 0.00045 20.3 1.2 0.00092 19.3 0.9 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCF48659.1 - 0.0014 18.5 0.1 0.0029 17.5 0.1 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.24 CCF48659.1 - 0.021 14.4 2.8 0.053 13.2 1.9 1.7 1 1 0 1 1 1 0 PHD-finger Nop14 PF04147.7 CCF48659.1 - 0.59 7.9 20.8 0.1 10.5 10.6 2.0 2 0 0 2 2 2 0 Nop14-like family PPP4R2 PF09184.6 CCF48659.1 - 2.7 7.4 16.5 0.054 13.0 5.7 2.0 2 0 0 2 2 2 0 PPP4R2 zf-RING_2 PF13639.1 CCF48659.1 - 7.3 6.5 9.8 1.4 8.7 4.2 1.8 2 0 0 2 2 2 0 Ring finger domain Sugar_tr PF00083.19 CCF48660.1 - 9.2e-79 265.1 18.6 1.1e-78 264.8 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF48660.1 - 4.8e-17 61.7 47.3 2.1e-15 56.3 12.4 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily PfkB PF00294.19 CCF48662.1 - 1.2e-39 136.2 0.0 1.6e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_1_2 PF00155.16 CCF48663.1 - 3.1e-87 292.8 0.1 3.6e-87 292.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II efThoc1 PF11957.3 CCF48664.1 - 1.1e-99 334.1 0.3 4.3e-44 150.8 0.0 3.3 2 1 1 3 3 3 3 THO complex subunit 1 transcription elongation factor CobN-Mg_chel PF02514.11 CCF48664.1 - 0.055 10.8 3.4 0.08 10.3 2.3 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase CENP-B_dimeris PF09026.5 CCF48664.1 - 6.8 7.0 9.8 1.1 9.4 0.8 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RRM_1 PF00076.17 CCF48665.1 - 3.4e-06 26.5 0.1 6.2e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48665.1 - 0.00051 19.9 0.1 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.4 CCF48666.1 - 1.2e-52 177.8 1.3 1.2e-52 177.8 0.9 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CCF48666.1 - 7.3e-16 58.3 0.1 2.3e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 CCF48666.1 - 0.011 15.3 0.5 0.018 14.6 0.3 1.4 1 0 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCF48666.1 - 0.072 12.8 0.4 0.2 11.4 0.3 1.8 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 S4 PF01479.20 CCF48666.1 - 0.12 11.8 0.0 21 4.6 0.0 3.3 3 0 0 3 3 3 0 S4 domain Pribosyltran PF00156.22 CCF48667.1 - 1.2e-16 60.5 0.1 1.8e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCF48667.1 - 0.0027 16.9 0.0 0.0044 16.2 0.0 1.4 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase SHR3_chaperone PF08229.6 CCF48670.1 - 1.7e-27 95.6 0.0 4.4e-27 94.3 0.0 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 SecG PF03840.9 CCF48670.1 - 0.01 15.5 0.3 0.027 14.1 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit UQ_con PF00179.21 CCF48672.1 - 2.1e-21 75.8 0.0 2.3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCF48672.1 - 0.0056 16.5 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain An_peroxidase PF03098.10 CCF48673.1 - 1.2e-82 278.0 0.0 5.1e-81 272.6 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase DUF883 PF05957.8 CCF48673.1 - 0.013 15.8 3.0 0.033 14.5 2.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) p450 PF00067.17 CCF48673.1 - 0.016 13.7 0.1 0.048 12.1 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 zf-HIT PF04438.11 CCF48674.1 - 5.7e-10 38.6 14.3 1.6e-09 37.2 6.4 2.5 2 0 0 2 2 2 2 HIT zinc finger zf-B_box PF00643.19 CCF48674.1 - 0.2 11.5 5.4 0.35 10.7 3.7 1.4 1 0 0 1 1 1 0 B-box zinc finger Gar1 PF04410.9 CCF48675.1 - 9.6e-41 138.8 0.1 9.6e-41 138.8 0.0 2.4 1 1 2 3 3 3 1 Gar1/Naf1 RNA binding region OPT PF03169.10 CCF48676.1 - 1.3e-159 532.5 37.1 1.5e-159 532.3 25.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.14 CCF48676.1 - 0.00017 21.1 4.0 0.44 10.0 0.4 3.6 3 0 0 3 3 3 2 VIT family TP2 PF01254.13 CCF48677.1 - 0.21 11.9 6.2 0.25 11.6 2.8 1.9 1 1 1 2 2 2 0 Nuclear transition protein 2 SET PF00856.23 CCF48677.1 - 0.43 10.8 3.5 0.47 10.7 2.4 1.1 1 0 0 1 1 1 0 SET domain DUF1977 PF09320.6 CCF48677.1 - 2.8 8.2 5.3 1.3 9.3 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1977) Metal_resist PF13801.1 CCF48677.1 - 3.1 7.8 6.0 6.3 6.8 4.1 1.6 1 1 0 1 1 1 0 Heavy-metal resistance Asp-B-Hydro_N PF05279.6 CCF48677.1 - 3.5 7.3 13.1 4.1 7.1 9.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Na_trans_assoc PF06512.8 CCF48677.1 - 4.1 7.3 9.8 4.9 7.0 6.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PBP_sp32 PF07222.7 CCF48677.1 - 5 6.2 12.8 6.2 5.9 8.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 CCF48677.1 - 8.6 4.9 16.7 10 4.7 11.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DnaJ PF00226.26 CCF48678.1 - 2.6e-23 81.5 0.3 3.8e-23 80.9 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain SSF PF00474.12 CCF48679.1 - 9.6e-17 60.7 27.9 1.3e-16 60.2 19.4 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Actin PF00022.14 CCF48680.1 - 3.4e-21 75.1 0.0 8.2e-11 40.9 0.0 3.1 3 0 0 3 3 3 3 Actin TPR_14 PF13428.1 CCF48681.1 - 2.6e-05 24.4 0.1 2.5 8.9 0.0 3.9 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48681.1 - 0.00017 21.8 3.1 0.051 13.9 0.1 3.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCF48681.1 - 0.00055 20.2 0.1 2.3 8.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF48681.1 - 0.00085 18.9 0.0 0.042 13.5 0.0 2.9 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 CCF48681.1 - 0.044 14.4 0.1 29 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.15 CCF48682.1 - 2.4e-56 189.4 2.4 2.6e-56 189.2 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPR_11 PF13414.1 CCF48683.1 - 4.1e-13 48.7 5.5 5.3e-09 35.6 0.8 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCF48683.1 - 5.5e-07 29.0 1.9 0.032 14.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCF48683.1 - 1.3e-05 24.5 1.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCF48683.1 - 0.0054 17.3 5.4 1.2 9.8 0.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF48683.1 - 0.0065 17.0 4.3 0.24 12.1 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCF48683.1 - 0.12 12.1 0.4 3.8 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCF48683.1 - 0.23 11.3 3.5 3.7 7.4 0.2 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.4 CCF48684.1 - 2.1e-34 117.6 0.3 2.9e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 CCF48684.1 - 4e-13 48.8 0.0 7.5e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit tRNA-synt_2 PF00152.15 CCF48685.1 - 1.8e-65 220.9 0.0 2.6e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Neugrin PF06413.6 CCF48685.1 - 2e-09 37.6 1.3 5.5e-09 36.1 0.9 1.8 1 0 0 1 1 1 1 Neugrin Oligomerisation PF02410.10 CCF48685.1 - 7.2e-08 32.3 0.0 3e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Oligomerisation domain MRP-L20 PF12824.2 CCF48685.1 - 0.00079 19.4 0.0 0.0021 18.0 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF4296 PF14129.1 CCF48685.1 - 0.098 12.8 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) PseudoU_synth_1 PF01416.15 CCF48686.1 - 1.3e-20 73.7 0.0 7.2e-11 42.4 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase Peptidase_C97 PF05903.9 CCF48687.1 - 1.1e-36 125.9 0.0 3.5e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 PPPDE putative peptidase domain PUL PF08324.6 CCF48687.1 - 1.1e-22 80.0 1.3 1.6e-22 79.6 0.9 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 CCF48687.1 - 1.7e-08 34.1 0.0 3.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin PITH PF06201.8 CCF48688.1 - 2.1e-36 124.9 0.0 3.6e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 CCF48688.1 - 3.5e-26 90.8 0.0 6.6e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CCF48688.1 - 0.00018 21.0 0.0 0.00048 19.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCF48688.1 - 0.00042 20.3 0.0 0.003 17.6 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CCF48688.1 - 0.0015 18.4 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCF48688.1 - 0.0017 18.5 0.1 0.01 16.0 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HLH PF00010.21 CCF48689.1 - 3.1e-09 36.3 0.6 1.3e-08 34.3 0.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NBP1 PF08537.5 CCF48689.1 - 0.0021 17.3 2.0 0.0037 16.5 1.4 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 RhoGAP PF00620.22 CCF48690.1 - 7.2e-48 162.0 0.0 1.2e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CCF48690.1 - 1.3e-14 54.1 1.1 7.9e-14 51.6 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Tropomyosin_1 PF12718.2 CCF48690.1 - 0.18 11.6 5.1 6.4 6.6 1.4 2.6 1 1 1 2 2 2 0 Tropomyosin like Pkinase PF00069.20 CCF48691.1 - 2e-70 236.9 0.0 2.6e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48691.1 - 8.8e-47 159.3 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCF48691.1 - 1.4e-21 76.6 0.1 4.3e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 CCF48691.1 - 6.1e-06 25.3 0.0 1.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCF48691.1 - 0.011 15.4 0.1 0.17 11.5 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 CCF48691.1 - 0.029 13.6 0.1 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 CCF48691.1 - 0.072 12.1 0.1 0.83 8.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 CCF48691.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF2810 PF10928.3 CCF48693.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Trp_syntA PF00290.15 CCF48694.1 - 5.3e-88 293.9 0.1 1e-87 292.9 0.1 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCF48694.1 - 9.6e-47 159.6 0.4 1.7e-46 158.8 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CCF48694.1 - 0.0026 17.0 0.2 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein Rad9 PF04139.8 CCF48695.1 - 5.9e-47 159.9 0.0 7.2e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Rad9 DUF605 PF04652.11 CCF48695.1 - 0.03 13.7 14.7 0.045 13.1 10.2 1.3 1 0 0 1 1 1 0 Vta1 like RINGv PF12906.2 CCF48696.1 - 1e-14 54.2 9.9 1.8e-14 53.4 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCF48696.1 - 0.3 10.9 10.3 0.53 10.1 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 CCF48696.1 - 3 7.7 6.1 7.2 6.5 4.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2256 PF10013.4 CCF48696.1 - 3.1 7.6 6.0 0.2 11.4 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DEAD PF00270.24 CCF48697.1 - 5.2e-43 146.4 0.0 8.7e-42 142.4 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48697.1 - 1e-22 79.7 0.2 3.8e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCHC PF00098.18 CCF48697.1 - 0.0027 17.5 0.5 0.0046 16.8 0.3 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1253 PF06862.7 CCF48697.1 - 0.079 11.3 0.0 1.5 7.1 0.0 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1253) zf-CCHC_4 PF14392.1 CCF48697.1 - 0.083 12.5 0.5 0.18 11.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Phage_endo_I PF05367.6 CCF48697.1 - 0.09 12.1 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Phage endonuclease I zf-CCHC_2 PF13696.1 CCF48697.1 - 0.14 11.6 0.3 0.38 10.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle ubiquitin PF00240.18 CCF48698.1 - 8.7e-35 117.9 0.7 1.4e-34 117.2 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CCF48698.1 - 3.7e-25 87.4 0.8 6.4e-25 86.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CCF48698.1 - 8e-20 70.3 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCF48698.1 - 1.2e-05 25.4 0.1 5e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCF48698.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCF48698.1 - 0.0011 18.8 0.2 0.0024 17.7 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 CCF48698.1 - 0.0027 17.5 0.4 0.0039 17.0 0.3 1.3 1 0 0 1 1 1 1 IBR domain DUF2407 PF10302.4 CCF48698.1 - 0.0087 16.2 0.3 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCF48698.1 - 0.063 13.3 0.3 0.12 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 CCF48698.1 - 0.09 11.3 0.1 0.097 11.2 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 CCF48698.1 - 0.14 10.4 1.6 3.4 5.8 0.0 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Med4 PF10018.4 CCF48699.1 - 5.1e-24 84.7 5.6 8.8e-24 83.9 3.9 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 G-patch PF01585.18 CCF48700.1 - 5e-06 26.2 2.5 5.2e-06 26.1 0.1 2.4 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 CCF48700.1 - 0.038 13.8 0.0 0.088 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDP-OH_P_transf PF01066.16 CCF48701.1 - 3.2e-12 46.6 2.8 3.2e-12 46.6 1.9 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UCH_1 PF13423.1 CCF48702.1 - 4.4e-45 154.3 0.0 6.9e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCF48702.1 - 1.7e-22 80.4 0.0 1.2e-20 74.4 0.0 2.5 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 CCF48702.1 - 0.00047 19.3 0.0 0.031 13.3 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 CCF48702.1 - 0.0033 17.2 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Fungal_trans PF04082.13 CCF48703.1 - 2.2e-05 23.4 0.0 6.8e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2419 PF10343.4 CCF48704.1 - 7.7e-07 28.6 0.1 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) RVT_2 PF07727.9 CCF48705.1 - 2.2e-52 177.5 0.0 3e-50 170.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF48705.1 - 1.1e-13 51.3 0.1 2.5e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Tim44 PF04280.10 CCF48707.1 - 1.1e-26 93.5 0.0 2.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain Pkinase PF00069.20 CCF48708.1 - 3.2e-55 187.1 0.0 4.6e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48708.1 - 1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF48708.1 - 0.0081 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCF48708.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CCF48708.1 - 0.096 12.2 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SAC3_GANP PF03399.11 CCF48710.1 - 8.3e-73 244.2 2.6 1.1e-72 243.8 1.8 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCF48710.1 - 5.7e-06 26.1 1.8 7e-06 25.8 0.2 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 COX5A PF02284.11 CCF48710.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Pollen_allerg_2 PF01620.11 CCF48710.1 - 0.31 11.3 8.8 0.36 11.1 0.1 3.1 3 0 0 3 3 3 0 Ribonuclease (pollen allergen) BAG PF02179.11 CCF48711.1 - 8.6e-12 44.9 2.1 2e-11 43.8 1.1 1.9 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.18 CCF48711.1 - 0.00068 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CDC37_N PF03234.9 CCF48711.1 - 0.063 13.6 1.6 0.089 13.1 1.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TarH PF02203.10 CCF48711.1 - 1.5 8.6 4.2 0.51 10.1 0.4 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue GHMP_kinases_N PF00288.21 CCF48712.1 - 5.7e-14 51.9 0.2 1.6e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCF48712.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal WD40 PF00400.27 CCF48713.1 - 2.3e-20 71.6 12.6 0.00081 19.1 0.2 6.9 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3373 PF11853.3 CCF48713.1 - 0.29 9.6 4.5 0.92 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF2514 PF10721.4 CCF48713.1 - 1.5 8.4 19.7 0.84 9.3 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) DUF4355 PF14265.1 CCF48713.1 - 6.8 6.6 12.3 0.99 9.3 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) PRP38 PF03371.10 CCF48714.1 - 4.1e-57 192.5 0.0 5.3e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ctr PF04145.10 CCF48715.1 - 3.7e-16 59.4 0.2 6.2e-16 58.7 0.2 1.3 1 0 0 1 1 1 1 Ctr copper transporter family HnRNPA1 PF11627.3 CCF48716.1 - 0.074 13.2 1.2 0.074 13.2 0.8 2.7 2 0 0 2 2 2 0 Nuclear factor hnRNPA1 AA_permease PF00324.16 CCF48717.1 - 2.5e-63 214.1 29.1 3.1e-63 213.8 20.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 CCF48718.1 - 5.2e-72 242.1 0.0 8.8e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_3 PF07859.8 CCF48718.1 - 2.8e-47 161.0 0.2 1.4e-46 158.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 CCF48718.1 - 3.7e-36 124.5 0.0 5.7e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2424 PF10340.4 CCF48718.1 - 1.6e-12 46.7 0.0 5e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) YrbL-PhoP_reg PF10707.4 CCF48718.1 - 1.5e-07 30.9 0.0 2.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Abhydrolase_5 PF12695.2 CCF48718.1 - 0.00091 19.0 0.1 0.0033 17.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Kdo PF06293.9 CCF48718.1 - 0.0013 17.8 0.4 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCF48718.1 - 0.083 11.6 0.1 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CCF48718.1 - 0.097 11.6 0.0 0.4 9.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DUF2422 PF10337.4 CCF48719.1 - 3.2e-112 375.6 3.6 9.2e-111 370.8 1.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CCF48719.1 - 1.5e-23 83.5 1.7 3.6e-13 49.6 0.0 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CCF48719.1 - 3.6e-07 30.1 18.6 3.6e-07 30.1 12.9 3.8 2 2 2 4 4 4 1 Fusaric acid resistance protein-like DUF1736 PF08409.6 CCF48719.1 - 0.015 14.8 0.4 0.015 14.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) ALMT PF11744.3 CCF48719.1 - 0.027 13.1 0.0 0.065 11.8 0.0 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Translin PF01997.11 CCF48720.1 - 4.1e-53 179.9 0.3 5.6e-53 179.5 0.2 1.2 1 0 0 1 1 1 1 Translin family UNC45-central PF11701.3 CCF48723.1 - 2.4e-06 27.2 4.8 1.8e-05 24.4 0.0 3.4 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Bac_luciferase PF00296.15 CCF48723.1 - 0.019 14.0 0.5 0.038 13.0 0.4 1.5 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF3385 PF11865.3 CCF48723.1 - 0.12 12.2 1.1 0.3 11.0 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) RNA_pol_Rpb1_5 PF04998.12 CCF48724.1 - 1.1e-94 316.8 0.4 1.5e-94 316.3 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCF48724.1 - 1.8e-88 297.0 0.0 2.6e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCF48724.1 - 1.4e-66 223.5 0.0 2.7e-66 222.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCF48724.1 - 1.7e-37 128.5 0.0 5e-37 127.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCF48724.1 - 4.4e-31 106.8 0.0 1.1e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Tox-MPTase2 PF15638.1 CCF48724.1 - 0.017 14.6 0.0 0.055 12.9 0.0 1.8 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Zn_Tnp_IS1 PF03811.8 CCF48724.1 - 0.021 14.2 0.1 0.063 12.7 0.1 1.8 1 0 0 1 1 1 0 InsA N-terminal domain Baculo_ME53 PF06061.6 CCF48724.1 - 0.03 13.3 0.1 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 DUF2225 PF09986.4 CCF48724.1 - 0.11 11.8 0.3 0.22 10.9 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Spherulin4 PF12138.3 CCF48725.1 - 1.2e-58 198.5 1.3 1.5e-58 198.1 0.9 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Sugar_tr PF00083.19 CCF48726.1 - 2.3e-70 237.4 29.6 2.1e-35 122.2 7.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF48726.1 - 4.2e-11 42.1 41.8 3.6e-07 29.2 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 CCF48727.1 - 1.2e-12 47.8 0.1 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DUF1793 PF08760.6 CCF48728.1 - 1.1e-66 223.8 0.2 2.7e-66 222.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) URO-D PF01208.12 CCF48729.1 - 1.9e-132 441.3 0.0 2.2e-132 441.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) HMG_box PF00505.14 CCF48730.1 - 3.5e-16 59.2 2.0 7.7e-16 58.1 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF48730.1 - 7.1e-13 48.7 1.4 1.3e-12 47.8 1.0 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 CCF48730.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.5 2 1 1 3 3 3 0 YABBY protein KRAB PF01352.22 CCF48730.1 - 0.16 11.4 0.4 0.3 10.5 0.3 1.3 1 0 0 1 1 1 0 KRAB box zf-CCCH PF00642.19 CCF48731.1 - 0.0079 15.8 8.2 0.013 15.1 5.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med26 PF08711.6 CCF48731.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.1 CCF48731.1 - 4.3 7.4 6.1 7.3 6.7 4.2 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DinB_2 PF12867.2 CCF48732.1 - 0.019 15.2 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 DinB superfamily DUF3461 PF11944.3 CCF48732.1 - 0.13 12.1 0.0 4.4 7.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) Vfa1 PF08432.5 CCF48734.1 - 2.8e-30 105.6 5.8 3e-29 102.3 4.0 2.0 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4231 PF14015.1 CCF48734.1 - 0.056 13.4 0.5 0.092 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Rad50_zn_hook PF04423.9 CCF48734.1 - 0.43 10.0 5.3 1.2 8.6 0.4 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif XRN_N PF03159.13 CCF48735.1 - 1.3e-105 352.0 0.0 2.4e-105 351.2 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 CCF48735.1 - 0.00045 20.0 2.6 0.00087 19.1 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle PMI_typeI PF01238.16 CCF48737.1 - 4.5e-108 361.5 0.0 5.3e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 CCF48737.1 - 0.00047 19.5 0.1 0.18 11.3 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 CCF48737.1 - 0.012 15.2 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 Cupin Cupin_3 PF05899.7 CCF48737.1 - 0.04 13.3 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF2834 PF11196.3 CCF48738.1 - 1.3e-05 25.2 17.7 0.03 14.4 1.0 4.4 4 0 0 4 4 4 3 Protein of unknown function (DUF2834) Strabismus PF06638.6 CCF48738.1 - 0.14 10.3 0.7 0.27 9.4 0.5 1.4 1 0 0 1 1 1 0 Strabismus protein CGI-121 PF08617.5 CCF48739.1 - 8.3e-46 155.5 0.0 1.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 NDUF_B7 PF05676.8 CCF48740.1 - 7.5e-28 95.7 2.9 8.9e-28 95.4 2.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 CCF48740.1 - 0.0011 18.6 2.2 0.0011 18.6 1.5 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2638 PF10937.3 CCF48741.1 - 1.1e-11 45.7 0.6 1.2e-11 45.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF4211 PF13926.1 CCF48742.1 - 7.3e-06 25.4 0.2 4.1e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) SR-25 PF10500.4 CCF48742.1 - 0.05 13.0 66.5 1.1 8.7 12.0 4.7 3 1 1 4 4 4 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 CCF48742.1 - 4.9 6.9 8.8 13 5.5 6.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SNARE PF05739.14 CCF48743.1 - 1.6e-15 56.5 0.3 1.6e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCF48743.1 - 1.3e-06 28.5 0.4 1.3e-06 28.5 0.2 3.0 2 2 1 3 3 3 1 Syntaxin Toxin_10 PF05431.6 CCF48743.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 Aida_N PF08910.5 CCF48743.1 - 0.43 10.8 2.6 0.48 10.6 0.4 1.9 2 0 0 2 2 2 0 Aida N-terminus PMT PF02366.13 CCF48744.1 - 1.6e-72 243.7 14.7 3.1e-72 242.8 10.2 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCF48744.1 - 3e-45 154.1 0.5 2.9e-44 150.9 0.4 2.3 1 1 0 1 1 1 1 MIR domain Abhydro_lipase PF04083.11 CCF48745.1 - 2.2e-16 58.9 0.0 5e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCF48745.1 - 0.00014 21.8 0.1 0.00028 20.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF48745.1 - 0.00042 19.9 0.1 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF48745.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec63 PF02889.11 CCF48746.1 - 1.9e-42 145.6 0.0 3.1e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 CCF48746.1 - 3.9e-15 55.3 0.3 1.1e-14 53.9 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 CCF48747.1 - 8.2e-30 103.5 0.0 1.9e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 PITH domain MAM33 PF02330.11 CCF48750.1 - 6.3e-28 97.9 0.1 8.2e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF1889 PF08986.5 CCF48750.1 - 0.065 13.4 0.1 0.3 11.2 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1889) RRM_6 PF14259.1 CCF48751.1 - 1.1e-14 54.0 0.0 1.5e-07 31.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF48751.1 - 2.8e-14 52.5 0.0 1.5e-05 24.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AF-4 PF05110.8 CCF48751.1 - 0.00031 18.8 22.8 0.00031 18.8 15.8 2.6 3 0 0 3 3 3 1 AF-4 proto-oncoprotein tRNA-synt_2b PF00587.20 CCF48752.1 - 1.9e-25 89.4 0.0 2.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF48752.1 - 0.0036 17.2 0.0 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain Acyl-CoA_dh_1 PF00441.19 CCF48753.1 - 1.9e-44 151.4 5.8 1.9e-44 151.4 4.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCF48753.1 - 1.5e-25 89.9 0.6 4.3e-25 88.4 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCF48753.1 - 1.6e-22 80.2 2.7 1.6e-22 80.2 1.9 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF48753.1 - 1.9e-17 62.4 0.0 4.5e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Snf7 PF03357.16 CCF48753.1 - 0.0045 16.3 3.8 0.0099 15.2 2.6 1.5 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 CCF48753.1 - 0.054 13.2 0.9 2.7 7.8 0.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit adh_short PF00106.20 CCF48754.1 - 3e-21 76.0 0.8 1.8e-20 73.5 0.4 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF48754.1 - 7.1e-20 71.7 0.0 9.5e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF48754.1 - 6.3e-06 25.9 0.0 1.3e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 KR domain DSPn PF14671.1 CCF48755.1 - 1.2e-35 122.5 0.0 1.3e-33 115.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCF48755.1 - 2.3e-13 49.8 0.1 6.5e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF48755.1 - 1.2e-05 24.7 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCF48755.1 - 0.093 12.7 0.2 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate ThiF PF00899.16 CCF48756.1 - 4.4e-46 156.0 0.0 7e-28 97.1 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CCF48756.1 - 5.1e-44 149.4 0.2 1.1e-43 148.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCF48756.1 - 3.6e-36 122.5 0.5 2e-24 84.9 0.0 2.7 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCF48756.1 - 2.8e-25 87.4 1.5 4e-22 77.3 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CCF48756.1 - 0.027 14.5 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CCF48756.1 - 0.065 12.3 0.1 0.67 9.0 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.23 CCF48758.1 - 2e-63 214.9 3.3 2.4e-63 214.6 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pap_E4 PF02711.9 CCF48758.1 - 0.19 12.5 3.1 0.94 10.3 2.4 1.9 2 0 0 2 2 2 0 E4 protein 2-Hacid_dh_C PF02826.14 CCF48759.1 - 1.4e-31 109.0 0.3 2.6e-31 108.1 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CCF48759.1 - 0.00095 18.2 0.3 0.0017 17.4 0.2 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 CCF48759.1 - 0.01 15.6 0.9 0.05 13.4 0.6 2.1 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.1 CCF48759.1 - 0.012 15.8 0.1 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCF48759.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3040 PF11239.3 CCF48760.1 - 0.027 14.4 0.3 0.098 12.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) V-SNARE PF05008.10 CCF48760.1 - 0.033 14.3 0.4 0.24 11.6 0.7 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PPR_2 PF13041.1 CCF48760.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 PPR repeat family Planc_extracel PF07595.7 CCF48761.1 - 0.11 12.2 4.2 0.076 12.7 0.7 2.4 2 0 0 2 2 2 0 Planctomycete extracellular ALG3 PF05208.8 CCF48763.1 - 4e-107 358.6 14.9 6.5e-107 357.9 10.3 1.3 1 0 0 1 1 1 1 ALG3 protein Gaa1 PF04114.9 CCF48763.1 - 1.3e-46 159.4 12.1 5.1e-44 150.8 2.2 3.9 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component TAF4 PF05236.9 CCF48764.1 - 6.1e-31 107.6 2.3 2.8e-29 102.2 1.6 2.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 CCF48764.1 - 0.092 12.4 4.3 0.055 13.1 0.9 2.2 1 1 1 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Got1 PF04178.7 CCF48765.1 - 2.6e-20 72.6 13.8 3.1e-20 72.4 9.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family LIM_bind PF01803.11 CCF48766.1 - 2.5e-36 125.0 0.0 2.3e-19 69.4 0.0 6.2 3 2 2 5 5 5 2 LIM-domain binding protein RVT_2 PF07727.9 CCF48767.1 - 2e-56 190.7 0.0 3.1e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF48767.1 - 9.4e-13 48.3 0.1 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Biotin_lipoyl PF00364.17 CCF48767.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF3546 PF12066.3 CCF48768.1 - 1.3e-15 57.3 2.4 6e-15 55.2 1.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CCF48768.1 - 4.1e-10 40.2 0.0 1.4e-09 38.5 0.0 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF1543 PF07566.7 CCF48768.1 - 0.045 13.2 0.2 0.21 11.1 0.2 2.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) RRM_1 PF00076.17 CCF48768.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G_like PF09088.6 CCF48769.1 - 4.1e-67 225.3 0.0 6.8e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCF48769.1 - 3.2e-36 124.8 0.4 9.6e-36 123.2 0.2 1.9 2 0 0 2 2 2 1 MIF4G like Spt4 PF06093.8 CCF48770.1 - 1.1e-32 111.6 0.1 1.3e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 CCF48770.1 - 0.068 12.5 0.7 0.084 12.2 0.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Cyclin_N PF00134.18 CCF48771.1 - 1.7e-12 46.9 0.3 2.3e-11 43.3 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCF48771.1 - 0.0013 18.6 0.9 0.61 10.0 0.0 3.0 2 1 1 3 3 3 2 Cyclin, C-terminal domain Abi PF02517.11 CCF48772.1 - 7.6e-12 45.2 12.4 3.5e-11 43.0 8.5 2.4 1 1 0 1 1 1 1 CAAX protease self-immunity NTPase_1 PF03266.10 CCF48773.1 - 0.027 14.1 0.4 4.1 7.0 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 CCF48773.1 - 0.029 14.1 0.1 0.41 10.4 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 CCF48773.1 - 0.079 13.1 0.1 0.24 11.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RICTOR_N PF14664.1 CCF48775.1 - 6.5e-83 278.3 1.3 1.8e-82 276.9 0.9 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CCF48775.1 - 7.4e-82 273.7 2.0 2.9e-80 268.4 0.1 3.2 3 1 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CCF48775.1 - 2.8e-35 120.7 2.0 2.4e-33 114.4 0.1 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CCF48775.1 - 1.6e-31 108.0 1.9 2.1e-29 101.2 0.1 4.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 CCF48775.1 - 1.5e-12 47.0 3.9 5.2e-12 45.3 2.7 2.0 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.17 CCF48775.1 - 0.055 13.5 4.3 12 6.2 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Na_trans_assoc PF06512.8 CCF48775.1 - 0.59 10.0 3.5 1.3 8.9 2.4 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.7 CCF48775.1 - 1.4 6.7 10.8 2.3 6.0 7.5 1.2 1 0 0 1 1 1 0 Nop14-like family Thioredoxin PF00085.15 CCF48776.1 - 3.1e-38 129.6 0.0 1.6e-20 72.7 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CCF48776.1 - 2e-14 53.8 0.0 3.7e-08 33.3 0.0 4.4 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCF48776.1 - 1.2e-08 35.0 0.2 0.0022 18.1 0.0 3.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF48776.1 - 5.4e-06 26.4 0.1 0.0076 16.3 0.0 4.0 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CCF48776.1 - 5.2e-05 23.1 0.0 0.0033 17.4 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.1 CCF48776.1 - 0.00012 22.1 2.0 0.17 11.9 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_3 PF13192.1 CCF48776.1 - 0.0011 18.6 0.0 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain AhpC-TSA PF00578.16 CCF48776.1 - 0.019 14.6 0.4 0.23 11.1 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family SSP160 PF06933.6 CCF48776.1 - 0.019 12.9 11.3 0.034 12.1 7.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CCF48776.1 - 0.7 7.5 1.6 0.99 7.0 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 CCF48776.1 - 0.82 9.4 9.8 1.9 8.2 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) His_biosynth PF00977.16 CCF48777.1 - 1.9e-33 115.6 0.0 6.3e-33 113.9 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein GST_N PF02798.15 CCF48777.1 - 3.1e-09 36.8 0.0 5.5e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCF48777.1 - 1.5e-05 25.1 0.1 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF48777.1 - 0.00023 21.1 0.0 0.00049 20.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCF48777.1 - 0.053 13.9 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF48777.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Actin PF00022.14 CCF48778.1 - 2.2e-159 530.0 0.0 2.5e-159 529.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CCF48778.1 - 0.088 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SLT PF01464.15 CCF48779.1 - 7.5e-16 57.7 0.1 1.7e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain Rad10 PF03834.9 CCF48780.1 - 2.8e-30 103.7 0.0 5.2e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CCF48780.1 - 0.0038 17.3 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.15 CCF48780.1 - 0.081 12.5 0.7 0.16 11.5 0.5 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_L2_C PF03947.13 CCF48781.1 - 1.4e-42 144.5 1.7 2.3e-42 143.8 1.2 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCF48781.1 - 5.1e-14 51.9 0.1 1.2e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DIM PF08194.7 CCF48783.1 - 1.1 9.2 2.8 1.8 8.5 1.9 1.3 1 0 0 1 1 1 0 DIM protein GTP_EFTU PF00009.22 CCF48786.1 - 1.5e-32 112.5 1.9 2.2e-32 112.0 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCF48786.1 - 3.6e-17 62.2 0.5 2.1e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCF48786.1 - 1.3e-14 54.0 4.6 4.8e-10 39.4 0.2 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF48786.1 - 2.5e-06 27.4 0.0 1.1e-05 25.4 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCF48786.1 - 0.011 15.8 0.1 0.056 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Cgr1 PF03879.9 CCF48787.1 - 2e-26 92.2 23.3 2.3e-26 92.0 16.2 1.0 1 0 0 1 1 1 1 Cgr1 family Phlebovirus_NSM PF07246.6 CCF48787.1 - 0.58 9.2 10.2 0.27 10.3 5.7 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M APG6 PF04111.7 CCF48787.1 - 0.63 9.0 7.6 0.61 9.0 5.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4637 PF15470.1 CCF48787.1 - 1 8.9 7.0 1.3 8.6 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Hom_end_hint PF05203.11 CCF48787.1 - 1.1 8.8 5.6 1.3 8.7 3.9 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint Carboxyl_trans PF01039.17 CCF48787.1 - 1.1 7.4 5.8 1.2 7.3 4.0 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain DUF4355 PF14265.1 CCF48787.1 - 1.6 8.6 19.1 2.1 8.2 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Borrelia_P83 PF05262.6 CCF48787.1 - 2.1 6.5 15.1 2.2 6.4 10.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.7 CCF48787.1 - 2.3 8.0 8.7 2.5 7.9 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atg14 PF10186.4 CCF48787.1 - 3.4 6.5 14.8 3.9 6.3 10.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bud13 PF09736.4 CCF48787.1 - 9.7 6.4 14.3 12 6.1 9.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2433 PF10360.4 CCF48788.1 - 2.2e-43 147.7 0.4 4.4e-43 146.7 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 CCF48788.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 CCF48788.1 - 0.0016 18.0 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48788.1 - 0.012 15.5 0.0 0.044 13.7 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 CCF48788.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain HLH PF00010.21 CCF48789.1 - 4.7e-16 58.2 0.2 8.9e-16 57.3 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyoxalase PF00903.20 CCF48789.1 - 0.019 14.9 0.2 0.034 14.1 0.2 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CPSase_L_D2 PF02786.12 CCF48790.1 - 2.4e-106 353.7 0.0 7.8e-82 273.6 0.0 2.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCF48790.1 - 2.2e-40 137.2 0.4 5.7e-40 135.9 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CCF48790.1 - 1.3e-37 129.3 0.2 3.2e-19 69.3 0.1 3.0 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 CCF48790.1 - 6.3e-35 119.6 0.0 2e-16 60.0 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CCF48790.1 - 4.1e-26 91.5 0.0 2.8e-10 39.4 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCF48790.1 - 2.1e-17 63.0 0.0 2.1e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCF48790.1 - 7.4e-14 51.6 0.1 2.9e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CCF48790.1 - 6e-11 42.1 0.0 6.1e-07 29.1 0.0 3.1 4 0 0 4 4 4 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCF48790.1 - 4.8e-07 29.7 0.0 5.9e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 CCF48790.1 - 2.5e-05 23.6 0.3 0.031 13.5 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 CCF48790.1 - 0.00076 19.3 0.0 0.0036 17.2 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Epimerase PF01370.16 CCF48790.1 - 0.0048 16.3 0.0 0.26 10.6 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Peptidase_M17_N PF02789.12 CCF48790.1 - 0.028 14.1 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Adeno_Penton_B PF01686.12 CCF48790.1 - 0.12 10.6 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus penton base protein Myb_DNA-binding PF00249.26 CCF48791.1 - 0.52 10.4 2.2 2.1 8.4 1.5 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain DEAD PF00270.24 CCF48792.1 - 4e-38 130.5 0.0 3.6e-37 127.4 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48792.1 - 1e-17 63.7 0.0 2.4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCF48792.1 - 2.3e-17 62.2 0.2 5.4e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCF48792.1 - 9.3e-06 25.5 0.1 5.1e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCF48792.1 - 0.33 10.6 1.7 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain SDA1 PF05285.7 CCF48793.1 - 9.1e-85 284.7 68.6 4.1e-43 147.9 21.6 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 CCF48793.1 - 1.2e-18 67.1 0.0 2.5e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 NUC130/3NT domain VTC PF09359.5 CCF48794.1 - 7.4e-104 346.7 0.0 1.6e-103 345.6 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CCF48794.1 - 3.5e-30 105.7 6.0 3.5e-30 105.7 4.2 3.5 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 CCF48794.1 - 1.5e-09 37.9 0.4 1.5e-09 37.9 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fork_head PF00250.13 CCF48795.1 - 2.6e-22 78.6 0.2 1.2e-21 76.4 0.1 2.1 1 1 0 1 1 1 1 Fork head domain Zip PF02535.17 CCF48795.1 - 0.0036 16.3 1.7 0.0061 15.5 1.2 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 CCF48795.1 - 0.77 9.0 12.3 1.7 7.9 8.5 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SH3_1 PF00018.23 CCF48797.1 - 2e-10 39.8 0.2 2.9e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF48797.1 - 2.6e-08 33.2 0.1 4e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF48797.1 - 1.9e-07 30.4 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Nop PF01798.13 CCF48798.1 - 1.2e-58 196.6 0.1 2.5e-58 195.6 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCF48798.1 - 8.4e-27 92.7 0.0 2.5e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCF48798.1 - 2.5e-18 66.0 0.1 2.5e-18 66.0 0.1 2.7 2 0 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 CCF48798.1 - 1.9 8.3 13.9 2.8 7.8 9.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Proteasome PF00227.21 CCF48799.1 - 8.4e-49 165.4 1.4 1.1e-45 155.2 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CCF48799.1 - 2.2e-15 55.6 0.4 3.9e-15 54.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chorion_S16 PF05836.7 CCF48799.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Chorion protein S16 Cpn60_TCP1 PF00118.19 CCF48800.1 - 4.2e-138 460.9 11.4 4.9e-138 460.7 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ABC_tran PF00005.22 CCF48802.1 - 4e-50 169.6 0.0 2.4e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCF48802.1 - 1.4e-47 162.3 11.7 1.7e-24 86.6 3.3 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 CCF48802.1 - 3.8e-11 43.4 0.3 1.3e-05 25.3 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCF48802.1 - 7.8e-11 42.2 0.8 2.9e-05 24.1 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CCF48802.1 - 1.9e-10 40.3 3.2 0.00034 19.9 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF48802.1 - 2e-09 36.8 0.8 2.8e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCF48802.1 - 2.2e-09 37.9 0.2 2.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCF48802.1 - 4.5e-08 32.8 0.1 0.0055 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 CCF48802.1 - 6e-08 32.3 0.0 0.00083 18.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 CCF48802.1 - 7e-07 29.3 0.8 0.014 15.2 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 CCF48802.1 - 6e-06 27.0 0.0 0.083 13.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 CCF48802.1 - 1.6e-05 23.9 0.0 0.0019 17.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 CCF48802.1 - 5.4e-05 23.5 0.0 0.76 10.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CCF48802.1 - 5.7e-05 23.0 0.4 0.16 11.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 CCF48802.1 - 6.4e-05 22.6 0.0 0.14 11.8 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CCF48802.1 - 0.00017 20.8 0.2 0.046 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCF48802.1 - 0.00024 21.2 1.1 0.77 9.9 0.0 3.9 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 CCF48802.1 - 0.00035 21.0 0.6 0.87 10.0 0.1 2.9 2 0 0 2 2 2 1 Miro-like protein TrwB_AAD_bind PF10412.4 CCF48802.1 - 0.00045 18.9 0.1 0.22 10.0 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 CCF48802.1 - 0.0006 18.9 0.2 0.15 11.1 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 CCF48802.1 - 0.0019 17.7 0.1 1.4 8.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 CCF48802.1 - 0.0024 17.6 0.2 0.019 14.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 CCF48802.1 - 0.0036 17.0 0.0 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase KAP_NTPase PF07693.9 CCF48802.1 - 0.0038 16.2 0.0 0.48 9.3 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 CCF48802.1 - 0.0052 16.3 0.9 4 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain DEAD PF00270.24 CCF48802.1 - 0.0067 15.9 0.2 11 5.4 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF815 PF05673.8 CCF48802.1 - 0.0085 15.0 0.0 3.2 6.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 CCF48802.1 - 0.01 15.4 1.6 1.2 8.8 0.1 2.8 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CCF48802.1 - 0.011 15.1 0.3 0.084 12.3 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CCF48802.1 - 0.015 15.2 0.0 0.78 9.6 0.0 3.2 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 CCF48802.1 - 0.015 15.4 0.2 9.5 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.21 CCF48802.1 - 0.016 14.6 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.10 CCF48802.1 - 0.019 13.6 0.0 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.12 CCF48802.1 - 0.022 14.1 0.3 9.9 5.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 CCF48802.1 - 0.048 13.8 0.1 9.1 6.4 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CCF48802.1 - 0.05 13.5 0.3 1.3 9.0 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CbiA PF01656.18 CCF48802.1 - 0.052 12.9 0.0 6.7 6.0 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 CCF48802.1 - 0.081 11.8 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CCF48802.1 - 0.1 12.3 0.1 26 4.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CCF48802.1 - 0.13 11.8 0.1 11 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CCF48802.1 - 0.32 10.5 3.1 2.6 7.5 0.0 3.5 4 1 0 5 5 4 0 AAA domain PhoH PF02562.11 CCF48802.1 - 0.34 10.1 0.9 15 4.7 0.0 2.9 3 0 0 3 3 3 0 PhoH-like protein AAA_33 PF13671.1 CCF48802.1 - 0.53 10.1 4.2 10 6.0 0.0 3.5 5 0 0 5 5 2 0 AAA domain AAA_15 PF13175.1 CCF48802.1 - 0.81 8.6 0.0 1.8 7.4 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain Dynamin_N PF00350.18 CCF48802.1 - 1.2 8.9 7.8 1.1 9.1 0.1 2.7 3 0 0 3 3 2 0 Dynamin family ABC_ATPase PF09818.4 CCF48802.1 - 2.7 6.4 5.3 8 4.9 0.0 2.8 4 0 0 4 4 3 0 Predicted ATPase of the ABC class ECR1_N PF14382.1 CCF48803.1 - 3.7e-05 22.9 0.0 6.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCF48803.1 - 0.043 13.7 0.0 0.17 11.8 0.0 2.0 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Myb_DNA-bind_2 PF08914.6 CCF48804.1 - 0.00057 19.6 1.8 0.44 10.3 0.0 3.3 2 1 0 2 2 2 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 CCF48804.1 - 0.0017 18.8 9.1 0.0027 18.2 0.5 3.5 3 0 0 3 3 3 1 Rap1, DNA-binding BRCT PF00533.21 CCF48804.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HSP70 PF00012.15 CCF48804.1 - 4.7 4.9 14.4 8.5 4.1 10.0 1.3 1 0 0 1 1 1 0 Hsp70 protein DHBP_synthase PF00926.14 CCF48805.1 - 1.7e-78 262.2 0.0 2e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TPR_1 PF00515.23 CCF48806.1 - 9.2e-08 31.3 7.0 0.014 15.0 0.6 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF48806.1 - 3.8e-07 29.5 29.3 0.069 13.1 0.6 9.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCF48806.1 - 1.1e-06 29.1 0.2 1.1e-06 29.1 0.1 11.5 13 1 0 13 13 13 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCF48806.1 - 9.2e-06 25.2 3.8 8.7e-05 22.0 0.2 10.1 9 3 3 13 13 13 3 TPR repeat TPR_8 PF13181.1 CCF48806.1 - 0.0018 17.9 5.6 29 4.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF48806.1 - 0.0044 17.5 49.5 0.038 14.6 0.5 11.8 12 1 1 13 13 13 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF48806.1 - 0.027 14.4 0.2 0.027 14.4 0.1 9.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF48806.1 - 0.05 14.0 24.7 0.33 11.5 0.1 10.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48806.1 - 0.7 10.2 0.0 0.7 10.2 0.0 12.2 11 3 1 13 13 13 0 Tetratricopeptide repeat SNO PF01174.14 CCF48807.1 - 1.4e-54 184.5 0.0 2.5e-43 147.9 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 CCF48807.1 - 1e-10 41.4 0.2 1.7e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 CCF48807.1 - 2e-06 27.4 0.0 0.00024 20.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 CCF48807.1 - 3.5e-05 23.6 0.0 6.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.19 CCF48807.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family BPL_N PF09825.4 CCF48807.1 - 0.005 15.6 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal DUF4066 PF13278.1 CCF48807.1 - 0.0082 15.4 0.1 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Putative amidotransferase Peptidase_C26 PF07722.8 CCF48807.1 - 0.13 11.6 0.3 1 8.7 0.0 2.3 2 1 0 2 2 2 0 Peptidase C26 CBFD_NFYB_HMF PF00808.18 CCF48808.1 - 2.2e-25 88.5 0.4 2.8e-25 88.1 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF48808.1 - 1.6e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 CCF48808.1 - 0.068 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Ribosomal_60s PF00428.14 CCF48808.1 - 7.7 6.9 8.3 18 5.8 5.7 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein PIP5K PF01504.13 CCF48809.1 - 1.2e-43 149.0 0.0 3.5e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase DUF4021 PF13213.1 CCF48809.1 - 0.22 11.1 0.3 0.68 9.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4021) Ric8 PF10165.4 CCF48810.1 - 2.5e-97 326.5 0.1 3e-96 322.9 0.1 2.0 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn PIG-X PF08320.7 CCF48811.1 - 4.1e-14 52.3 0.1 1.8e-05 24.0 0.0 3.4 3 1 0 3 3 3 3 PIG-X / PBN1 SNF2_N PF00176.18 CCF48813.1 - 1.2e-63 214.6 3.0 5.8e-63 212.4 2.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF48813.1 - 1e-14 54.1 0.0 3.3e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribosomal_60s PF00428.14 CCF48813.1 - 0.22 11.9 16.9 0.044 14.1 0.9 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_N PF08240.7 CCF48814.1 - 1.3e-27 95.6 2.6 4e-27 94.1 1.8 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF48814.1 - 7.8e-21 73.9 1.1 2e-20 72.6 0.5 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCF48814.1 - 0.00037 19.7 0.1 0.00072 18.7 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCF48814.1 - 0.092 13.1 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Asp PF00026.18 CCF48815.1 - 2.1e-07 30.5 1.0 0.0027 16.9 0.3 3.1 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF48815.1 - 0.00029 20.8 1.4 0.00053 19.9 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCF48815.1 - 0.012 16.1 1.3 7.7 7.0 0.0 3.8 3 1 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.1 CCF48815.1 - 0.017 14.9 0.0 16 5.3 0.0 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Mur_ligase_M PF08245.7 CCF48816.1 - 3e-05 24.1 0.0 7.6e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Glyco_hydro_cc PF11790.3 CCF48817.1 - 1.9e-62 210.8 9.2 2.3e-62 210.5 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 CCF48817.1 - 0.00062 18.6 1.4 0.00095 18.0 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 53 Glyco_hydro_2_C PF02836.12 CCF48817.1 - 0.003 16.4 0.1 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Med13_C PF06333.7 CCF48818.1 - 0.00058 18.5 1.0 0.00058 18.5 0.7 3.9 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal PPR_2 PF13041.1 CCF48819.1 - 1e-47 159.8 2.2 6.5e-11 42.0 0.0 11.8 8 3 5 13 13 13 9 PPR repeat family PPR_3 PF13812.1 CCF48819.1 - 1.7e-38 127.6 10.9 9.4e-05 22.3 0.0 14.6 15 0 0 15 15 15 8 Pentatricopeptide repeat domain PPR PF01535.15 CCF48819.1 - 1.4e-30 103.1 11.8 9.9e-05 22.0 0.0 13.4 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 CCF48819.1 - 1.3e-24 85.3 4.6 9.6e-07 28.1 0.0 9.7 10 0 0 10 10 10 4 PPR repeat Methyltransf_11 PF08241.7 CCF48819.1 - 4.9e-14 52.5 0.0 1.3e-12 48.0 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF48819.1 - 6.3e-11 42.0 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF48819.1 - 1e-09 38.3 0.0 3e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF48819.1 - 1.3e-09 38.4 0.0 7.2e-09 36.0 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF48819.1 - 4.5e-07 29.2 0.0 1.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPR_14 PF13428.1 CCF48819.1 - 2.9e-06 27.3 8.1 0.28 11.9 0.0 8.7 7 2 2 9 9 8 1 Tetratricopeptide repeat Methyltransf_25 PF13649.1 CCF48819.1 - 6.4e-05 23.2 0.0 0.00055 20.2 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain RPM2 PF08579.6 CCF48819.1 - 0.00045 20.3 0.0 0.23 11.5 0.0 3.9 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) Methyltransf_18 PF12847.2 CCF48819.1 - 0.00083 19.9 0.0 0.0077 16.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCF48819.1 - 0.0034 17.0 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain TPR_16 PF13432.1 CCF48819.1 - 0.0081 16.8 21.0 0.16 12.6 0.0 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCF48819.1 - 0.068 13.0 0.1 13 5.9 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Kinesin PF00225.18 CCF48820.1 - 5.9e-110 367.1 0.1 9.3e-110 366.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 CCF48820.1 - 4.6e-37 126.8 0.0 1.7e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 CCF48820.1 - 8.9e-13 48.3 0.0 3.3e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 CCF48820.1 - 5.3e-08 32.7 0.1 1.6e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CCF48820.1 - 3.7e-06 26.9 0.0 1.5e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 CCF48820.1 - 0.00068 19.8 1.2 0.0026 18.0 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Ribosomal_60s PF00428.14 CCF48820.1 - 9.1 6.7 14.1 13 6.2 2.0 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 CCF48823.1 - 5e-22 78.0 0.1 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF48823.1 - 5.2e-08 32.6 10.1 1e-07 31.7 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF48824.1 - 8.7e-18 64.1 0.0 1.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF48824.1 - 8.1e-09 35.2 9.8 1.4e-08 34.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC PF00098.18 CCF48825.1 - 0.027 14.3 1.5 0.06 13.2 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF99 PF01949.11 CCF48825.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF544 PF04424.8 CCF48826.1 - 5.3e-16 58.5 0.0 2.1e-15 56.5 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF544) Aminotran_4 PF01063.14 CCF48826.1 - 6.7e-10 38.8 0.0 6.3e-09 35.6 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class IV RdRP PF05183.7 CCF48827.1 - 6.2e-134 447.8 0.0 8.2e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 CCF48827.1 - 0.046 13.7 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) P-mevalo_kinase PF04275.9 CCF48828.1 - 0.0071 16.0 0.1 0.016 14.9 0.1 1.6 1 1 0 1 1 1 1 Phosphomevalonate kinase RVT_2 PF07727.9 CCF48829.1 - 8.8e-42 142.7 0.1 2.3e-41 141.4 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pro_isomerase PF00160.16 CCF48830.1 - 1.5e-44 151.9 0.1 2.5e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCF48830.1 - 0.00042 19.9 2.1 0.12 12.0 0.1 2.4 2 0 0 2 2 2 2 TPR repeat Cadherin_pro PF08758.6 CCF48830.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Cadherin prodomain like TPR_1 PF00515.23 CCF48830.1 - 0.14 11.7 4.4 1.4 8.6 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCF48830.1 - 0.29 11.1 4.5 3.7 7.7 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Tcf25 PF04910.9 CCF48831.1 - 1e-99 333.9 0.0 3.2e-99 332.3 0.0 1.7 2 0 0 2 2 2 1 Transcriptional repressor TCF25 DUF4604 PF15377.1 CCF48831.1 - 0.53 10.4 26.8 1.3 9.1 18.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) TFIIF_alpha PF05793.7 CCF48831.1 - 3.7 5.7 25.1 7.3 4.8 17.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SCO1-SenC PF02630.9 CCF48832.1 - 5.1e-57 192.2 0.0 7.6e-57 191.7 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CCF48832.1 - 0.0005 20.1 0.0 0.00091 19.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CCF48832.1 - 0.0071 16.0 0.0 0.019 14.6 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Eaf7 PF07904.8 CCF48833.1 - 1.4e-10 40.9 0.6 0.00048 20.0 0.0 3.4 2 1 0 2 2 2 2 Chromatin modification-related protein EAF7 ACOX PF01756.14 CCF48834.1 - 1.6e-18 66.7 0.0 2.6e-17 62.7 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CCF48834.1 - 2.9e-13 50.2 0.3 5.3e-13 49.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CCF48834.1 - 2e-10 39.9 0.2 5.1e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Methyltransf_18 PF12847.2 CCF48835.1 - 9.6e-07 29.3 0.0 2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF48835.1 - 0.00019 21.2 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF48835.1 - 0.0013 19.1 0.0 0.0042 17.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF48835.1 - 0.018 15.5 0.0 0.076 13.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCF48835.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CCF48835.1 - 0.072 13.4 0.0 0.35 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CCF48835.1 - 0.11 12.1 0.0 0.43 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Fumble PF03630.9 CCF48836.1 - 1.8e-113 378.8 0.0 4.1e-86 288.9 0.0 3.1 3 0 0 3 3 3 3 Fumble V-SNARE PF05008.10 CCF48837.1 - 1.1e-21 76.7 12.5 2.8e-21 75.4 2.6 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CCF48837.1 - 1.1e-16 60.6 6.9 1.1e-16 60.6 4.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF883 PF05957.8 CCF48837.1 - 0.00013 22.2 10.2 0.048 14.0 0.2 3.1 1 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 CCF48837.1 - 0.00015 21.8 7.4 0.0054 16.7 0.9 2.1 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) Sec20 PF03908.8 CCF48837.1 - 0.0014 18.3 0.4 0.0014 18.3 0.3 1.9 2 0 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 CCF48837.1 - 0.0033 15.5 0.4 0.0033 15.5 0.3 1.6 2 0 0 2 2 2 1 Fusion glycoprotein F0 YqjK PF13997.1 CCF48837.1 - 0.029 14.5 1.2 0.029 14.5 0.9 1.9 2 0 0 2 2 1 0 YqjK-like protein DUF3391 PF11871.3 CCF48837.1 - 0.043 14.0 11.0 0.38 10.9 1.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) Prominin PF05478.6 CCF48837.1 - 0.047 11.2 5.3 0.081 10.4 3.6 1.5 1 1 0 1 1 1 0 Prominin T2SF PF00482.18 CCF48837.1 - 0.048 13.5 1.7 0.89 9.4 1.2 2.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF912 PF06024.7 CCF48837.1 - 0.048 13.7 1.6 0.091 12.8 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PTS_IIA PF02255.11 CCF48837.1 - 0.063 13.1 2.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit YukC PF10140.4 CCF48837.1 - 0.071 11.6 0.7 0.11 11.0 0.0 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Synaptobrevin PF00957.16 CCF48837.1 - 0.33 10.5 2.9 0.21 11.2 0.2 2.0 2 0 0 2 2 2 0 Synaptobrevin BLOC1_2 PF10046.4 CCF48837.1 - 0.76 9.9 7.9 0.8 9.8 0.2 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COX4_pro_2 PF07835.7 CCF48837.1 - 1.3 9.0 3.3 1.2 9.1 0.9 1.8 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Sigma_reg_N PF13800.1 CCF48837.1 - 2 8.5 6.1 0.89 9.6 2.5 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CASP_C PF08172.7 CCF48837.1 - 2.4 7.1 8.8 0.84 8.6 0.6 2.4 1 1 1 2 2 2 0 CASP C terminal Sec8_exocyst PF04048.9 CCF48837.1 - 3 7.4 7.3 0.82 9.2 0.5 2.4 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 CCF48837.1 - 3.1 7.6 5.7 1.7 8.4 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.9 CCF48837.1 - 8.9 6.2 16.1 5.6 6.8 3.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Myotub-related PF06602.9 CCF48838.1 - 2.5e-119 398.2 0.0 3.1e-118 394.5 0.0 2.0 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CCF48838.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Vps36_ESCRT-II PF11605.3 CCF48838.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Y_phosphatase PF00102.22 CCF48838.1 - 0.021 14.1 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GRAM PF02893.15 CCF48838.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.15 CCF48838.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cation_efflux PF01545.16 CCF48839.1 - 2.4e-43 148.2 8.2 3.6e-43 147.6 5.7 1.3 1 0 0 1 1 1 1 Cation efflux family Myb_DNA-bind_6 PF13921.1 CCF48839.1 - 0.061 13.4 0.3 0.21 11.7 0.2 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain WD40 PF00400.27 CCF48840.1 - 3.1e-08 33.1 11.5 0.0062 16.3 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCF48840.1 - 0.088 11.5 0.0 3.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Nup133 N terminal like RF-1 PF00472.15 CCF48841.1 - 1.6e-17 63.2 1.6 2.1e-17 62.9 1.1 1.1 1 0 0 1 1 1 1 RF-1 domain GCS PF03074.11 CCF48842.1 - 1.1e-162 541.2 0.0 7e-129 430.0 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase DUF1769 PF08588.5 CCF48843.1 - 4.3e-25 87.4 0.2 7.8e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) KH_1 PF00013.24 CCF48844.1 - 1.1e-08 34.6 0.1 3.3e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CCF48844.1 - 2.5e-05 23.8 2.9 0.00049 19.6 0.2 2.8 2 0 0 2 2 2 1 KH domain Trp_repressor PF01371.14 CCF48844.1 - 0.016 15.1 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein PGI PF00342.14 CCF48845.1 - 2.4e-210 699.0 0.2 2.8e-210 698.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase HMG_box_2 PF09011.5 CCF48846.1 - 1.5e-16 60.4 11.8 1e-10 41.8 0.3 2.9 3 0 0 3 3 3 2 HMG-box domain HMG_box PF00505.14 CCF48846.1 - 2.3e-16 59.8 21.5 6.2e-11 42.4 1.2 3.9 3 2 0 3 3 3 2 HMG (high mobility group) box GCV_T PF01571.16 CCF48848.1 - 4.6e-13 49.0 0.0 2.8e-12 46.4 0.0 2.3 3 1 0 3 3 3 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCF48848.1 - 6e-07 29.4 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain AhpC-TSA_2 PF13911.1 CCF48849.1 - 1.2e-12 47.7 0.0 2.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 CCF48849.1 - 7.3e-09 35.3 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCF48849.1 - 1.9e-07 30.7 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin Plasmodium_Vir PF05795.6 CCF48849.1 - 0.27 10.4 0.5 1.2 8.2 0.3 2.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LtrA PF06772.6 CCF48850.1 - 4.9e-18 65.1 12.3 6.8e-09 35.0 5.3 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2207 PF09972.4 CCF48850.1 - 2.4 6.6 5.9 6.7 5.1 4.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNB PF00773.14 CCF48851.1 - 1.9e-50 171.9 0.0 4.5e-50 170.7 0.0 1.7 1 1 0 1 1 1 1 RNB domain Ribul_P_3_epim PF00834.14 CCF48851.1 - 0.22 10.6 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Ras PF00071.17 CCF48852.1 - 2.3e-35 121.3 0.1 2.7e-35 121.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF48852.1 - 1.6e-22 80.2 0.0 7.5e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCF48852.1 - 4.2e-08 32.6 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF48852.1 - 2.8e-07 29.9 0.1 3.4e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF48852.1 - 7.8e-05 22.1 0.0 0.00065 19.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF48852.1 - 0.0043 16.9 0.0 0.0075 16.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CCF48852.1 - 0.042 12.5 0.1 0.097 11.3 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit SRPRB PF09439.5 CCF48852.1 - 0.047 12.8 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PBP5_C PF07943.8 CCF48852.1 - 0.064 13.2 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Penicillin-binding protein 5, C-terminal domain PduV-EutP PF10662.4 CCF48852.1 - 0.083 12.3 0.1 0.28 10.6 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PAPA-1 PF04795.7 CCF48853.1 - 5.9e-14 52.5 8.3 5.9e-14 52.5 5.8 4.9 5 1 0 5 5 5 1 PAPA-1-like conserved region Med3 PF11593.3 CCF48853.1 - 0.92 8.6 17.4 1.9 7.6 12.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nse4_C PF08743.5 CCF48854.1 - 0.1 12.6 0.2 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 Nse4 C-terminal RNA_pol_Rpc4 PF05132.9 CCF48854.1 - 1.3 9.0 4.9 0.16 11.9 0.5 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 HUN PF08729.5 CCF48856.1 - 2.6e-11 43.1 1.5 2.6e-11 43.1 1.1 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 CCF48856.1 - 3.7e-08 33.3 0.8 3.7e-08 33.3 0.5 2.2 2 0 0 2 2 2 1 Ubinuclein conserved middle domain DUF815 PF05673.8 CCF48857.1 - 0.037 12.9 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NMD3 PF04981.8 CCF48858.1 - 1.8e-80 269.4 2.6 1.8e-80 269.4 1.8 2.0 2 0 0 2 2 2 1 NMD3 family DZR PF12773.2 CCF48858.1 - 0.0065 16.2 5.7 0.071 12.9 3.1 2.7 2 1 1 3 3 3 2 Double zinc ribbon zf-C3HC4_3 PF13920.1 CCF48858.1 - 1.5 8.5 6.0 0.23 11.1 0.4 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2340 PF10209.4 CCF48859.1 - 1.6e-47 160.6 2.0 1.9e-47 160.3 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Daxx PF03344.10 CCF48861.1 - 0.0056 15.2 14.2 0.0064 15.0 9.8 1.0 1 0 0 1 1 1 1 Daxx Family DUF1510 PF07423.6 CCF48861.1 - 0.032 13.6 9.5 0.036 13.4 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CCF48861.1 - 0.036 14.1 5.3 0.039 13.9 3.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 CCF48861.1 - 0.11 10.5 10.1 0.11 10.4 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_YhcN_YlaJ PF09580.5 CCF48861.1 - 0.15 12.1 16.0 0.19 11.8 11.1 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BUD22 PF09073.5 CCF48861.1 - 0.3 10.1 9.7 0.34 9.9 6.8 1.0 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 CCF48861.1 - 0.52 9.5 8.2 0.56 9.3 5.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NOA36 PF06524.7 CCF48861.1 - 0.71 9.0 14.9 0.85 8.8 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop25 PF09805.4 CCF48861.1 - 1.1 9.2 9.1 1.5 8.8 6.3 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) FimP PF09766.4 CCF48861.1 - 1.2 8.1 14.7 1.3 8.0 10.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Nop14 PF04147.7 CCF48861.1 - 1.3 6.8 12.7 1.3 6.8 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.1 CCF48861.1 - 1.3 6.6 7.1 1.4 6.5 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1754 PF08555.5 CCF48861.1 - 1.6 9.4 9.4 2.6 8.6 6.5 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2076 PF09849.4 CCF48861.1 - 2.1 8.3 20.7 2.6 8.0 14.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pox_Ag35 PF03286.9 CCF48861.1 - 2.2 7.7 13.2 2.7 7.4 9.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GOLD_2 PF13897.1 CCF48861.1 - 2.8 8.1 5.0 4.7 7.4 3.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CobT PF06213.7 CCF48861.1 - 5 6.1 16.1 5.9 5.9 11.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 CCF48861.1 - 8.3 5.1 10.8 9.5 4.9 7.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF506 PF04720.7 CCF48861.1 - 8.6 5.9 9.1 12 5.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Gti1_Pac2 PF09729.4 CCF48861.1 - 9.1 6.1 8.5 8.4 6.2 5.3 1.3 1 1 0 1 1 1 0 Gti1/Pac2 family Whi5 PF08528.6 CCF48862.1 - 4.8e-06 26.0 0.1 9.8e-06 25.0 0.1 1.5 1 0 0 1 1 1 1 Whi5 like TRAPP PF04051.11 CCF48863.1 - 3e-34 117.7 0.0 4.4e-34 117.2 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component dsDNA_bind PF01984.15 CCF48864.1 - 2.1e-29 101.6 2.9 3.4e-29 100.9 2.0 1.4 1 1 0 1 1 1 1 Double-stranded DNA-binding domain DGCR6 PF07324.6 CCF48864.1 - 0.11 11.9 2.2 0.14 11.6 1.5 1.1 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Steroid_dh PF02544.11 CCF48865.1 - 2.7e-26 92.1 5.7 1.7e-19 70.0 3.7 4.4 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CCF48865.1 - 0.00026 20.3 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FDC-SP PF15215.1 CCF48865.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.3 3 1 1 4 4 4 0 Follicular dendritic cell secreted peptide RVT_2 PF07727.9 CCF48866.1 - 1.6e-13 50.2 0.1 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) JmjC PF02373.17 CCF48867.1 - 1.5e-15 57.3 0.0 4.4e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CCF48867.1 - 4.7e-07 29.5 0.1 0.048 13.1 0.0 3.4 3 0 0 3 3 3 2 Cupin-like domain zf-B_box PF00643.19 CCF48867.1 - 0.11 12.3 6.0 0.28 11.1 4.2 1.6 1 0 0 1 1 1 0 B-box zinc finger RVT_2 PF07727.9 CCF48868.1 - 4.5e-37 127.3 1.0 4.9e-23 81.3 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF48868.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) FKBP_C PF00254.23 CCF48869.1 - 6.5e-32 109.4 0.0 7.5e-32 109.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Maf1 PF09174.5 CCF48871.1 - 5.2e-35 120.9 0.1 1.1e-28 100.3 0.0 2.4 2 0 0 2 2 2 2 Maf1 regulator TruD PF01142.13 CCF48872.1 - 3.6e-57 193.7 0.0 1.5e-52 178.5 0.0 4.9 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Gly-rich_Ago1 PF12764.2 CCF48872.1 - 0.28 11.8 0.1 0.28 11.8 0.1 3.0 2 0 0 2 2 2 0 Glycine-rich region of argonaut Glyco_hydro_3 PF00933.16 CCF48873.1 - 5.8e-79 265.1 0.0 8.5e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCF48873.1 - 1.8e-48 165.0 0.1 3.1e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCF48873.1 - 1.4e-20 72.9 0.1 2.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PGAP1 PF07819.8 CCF48874.1 - 4.2e-56 190.0 0.0 6.2e-56 189.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Luteo_Vpg PF01659.11 CCF48876.1 - 0.001 18.6 3.3 5.3 6.7 0.1 3.3 3 0 0 3 3 3 3 Luteovirus putative VPg genome linked protein Abhydrolase_3 PF07859.8 CCF48880.1 - 1.7e-16 60.4 0.1 3.2e-16 59.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCF48880.1 - 6e-11 41.6 0.0 3.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCF48880.1 - 0.00011 22.0 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF48880.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3605 PF12239.3 CCF48881.1 - 1.4e-20 73.6 0.0 1.2e-05 25.1 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) GMC_oxred_N PF00732.14 CCF48882.1 - 4.2e-58 196.8 0.0 5.6e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF48882.1 - 1.5e-31 109.6 0.1 4e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCF48882.1 - 7.9e-06 24.9 1.4 0.00022 20.1 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCF48882.1 - 7.6e-05 22.6 0.8 0.00043 20.2 1.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCF48882.1 - 0.0014 18.7 3.8 0.36 10.8 1.7 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF48882.1 - 0.0018 17.2 3.6 0.0077 15.1 2.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCF48882.1 - 0.0041 16.0 0.5 0.0067 15.3 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCF48882.1 - 0.02 13.9 0.6 0.049 12.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 CCF48882.1 - 0.082 12.7 3.2 0.16 11.8 1.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Solute_trans_a PF03619.11 CCF48884.1 - 1.3e-72 244.4 27.4 1.7e-72 244.0 19.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 CCF48884.1 - 7.8 6.4 11.1 0.11 12.3 2.3 1.9 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WD40 PF00400.27 CCF48885.1 - 1.2e-16 59.9 9.7 1.7e-06 27.6 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 CCF48886.1 - 1.6e-06 27.8 7.8 3.1e-06 26.9 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 CCF48887.1 - 3.8e-126 421.1 0.2 4.3e-126 420.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF48887.1 - 7.2e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 CCF48887.1 - 0.0018 17.5 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) CPL PF08144.6 CCF48887.1 - 0.0029 17.4 0.0 0.0095 15.7 0.0 1.9 1 0 0 1 1 1 1 CPL (NUC119) domain HORMA PF02301.13 CCF48888.1 - 2.2e-42 144.9 0.0 2.5e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain zf-RING_2 PF13639.1 CCF48889.1 - 2.5e-11 43.2 1.4 2.5e-11 43.2 1.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_3 PF14369.1 CCF48889.1 - 4.8e-09 36.0 0.8 4.8e-09 36.0 0.6 2.9 3 0 0 3 3 3 1 zinc-finger zf-C3HC4_3 PF13920.1 CCF48889.1 - 1.4e-08 34.2 9.9 4.6e-06 26.2 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF48889.1 - 4.1e-08 33.1 1.4 4.1e-08 33.1 1.0 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCF48889.1 - 1.2e-05 25.2 1.3 1.2e-05 25.2 0.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF48889.1 - 6.3e-05 22.6 11.8 0.0002 21.0 0.2 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCF48889.1 - 0.00032 20.3 0.5 0.00032 20.3 0.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF48889.1 - 0.0029 17.4 0.5 0.0029 17.4 0.3 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 CCF48889.1 - 0.039 13.7 5.7 0.15 11.8 0.2 3.0 3 0 0 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.1 CCF48889.1 - 0.082 12.5 9.7 0.9 9.1 0.1 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-TFIIB PF13453.1 CCF48889.1 - 0.28 10.3 5.9 6.5 6.0 0.1 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.14 CCF48889.1 - 4.3 7.0 7.1 0.45 10.2 0.2 2.3 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family His_Phos_1 PF00300.17 CCF48890.1 - 2.1e-15 57.1 0.0 4.9e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GMP_synt_C PF00958.17 CCF48891.1 - 3.9e-40 135.4 0.0 8.6e-40 134.3 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CCF48891.1 - 7.4e-37 126.6 0.0 1.4e-36 125.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CCF48891.1 - 6.1e-12 44.9 0.1 1.4e-07 30.6 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CCF48891.1 - 7.7e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 CCF48891.1 - 4.6e-05 22.1 0.2 8.5e-05 21.2 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 CCF48891.1 - 6.5e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 CCF48891.1 - 0.00078 18.5 0.2 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CCF48891.1 - 0.00082 18.9 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CCF48891.1 - 0.0016 17.7 0.0 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 CCF48891.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 CCF48891.1 - 0.084 13.2 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 CCF48891.1 - 0.12 11.8 0.2 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 PP-loop family IF3_C PF00707.17 CCF48892.1 - 4.2e-05 23.2 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 CCF48892.1 - 0.00058 19.2 2.1 0.00083 18.7 0.6 1.9 1 1 0 1 1 1 1 Mitochondrial translation initiation factor DUF1908 PF08926.6 CCF48892.1 - 0.0042 15.8 0.7 0.0042 15.8 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) ATP-synt_E_2 PF08112.6 CCF48892.1 - 0.25 11.4 0.0 0.25 11.4 0.0 2.3 3 0 0 3 3 3 0 ATP synthase epsilon subunit Chorion_2 PF03964.10 CCF48892.1 - 1.5 9.4 7.0 2.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Chorion family 2 Herpes_capsid PF06112.6 CCF48892.1 - 6.2 6.8 14.4 1.9 8.5 3.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein WD40 PF00400.27 CCF48893.1 - 1e-16 60.0 5.8 3.7e-05 23.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.15 CCF48894.1 - 8.9e-19 67.0 0.0 7.7e-18 63.9 0.0 2.3 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CCF48894.1 - 0.005 15.8 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II NP1-WLL PF11733.3 CCF48894.1 - 0.061 13.5 0.5 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Non-capsid protein NP1 FliX PF10768.4 CCF48895.1 - 0.0026 18.0 1.1 0.0096 16.1 0.7 1.9 1 0 0 1 1 1 1 Class II flagellar assembly regulator PBP_dimer PF03717.10 CCF48895.1 - 0.065 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain ParA PF10609.4 CCF48896.1 - 7.8e-35 118.6 0.0 1.4e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCF48896.1 - 1.5e-10 40.8 0.1 2e-09 37.1 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CCF48896.1 - 0.00028 20.0 0.6 0.0026 16.8 0.4 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 CCF48896.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCF48896.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 CCF48896.1 - 0.14 11.6 0.0 0.87 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 CCF48896.1 - 0.16 11.4 0.1 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E F-box PF00646.28 CCF48898.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain DUF4407 PF14362.1 CCF48898.1 - 1.1 8.1 4.2 3.4 6.5 2.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TOM13 PF08219.6 CCF48899.1 - 1.6e-09 37.4 2.7 3.1e-09 36.4 1.9 1.7 1 1 0 1 1 1 1 Outer membrane protein TOM13 TPR_2 PF07719.12 CCF48900.1 - 3.8e-29 98.2 13.0 5.7e-05 22.7 0.1 9.2 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 CCF48900.1 - 3.5e-25 87.4 14.2 1.6e-08 34.0 0.0 7.5 5 1 5 10 10 10 7 TPR repeat TPR_1 PF00515.23 CCF48900.1 - 3.5e-24 83.3 4.1 5.6e-06 25.7 0.1 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 CCF48900.1 - 3e-18 65.7 13.8 2.4e-08 33.9 1.3 5.0 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCF48900.1 - 1.2e-14 54.5 18.4 3.1e-06 27.7 0.0 6.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF48900.1 - 1.4e-14 52.6 0.0 0.087 12.6 0.0 7.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCF48900.1 - 2e-14 53.2 13.9 1.5e-05 24.8 0.0 7.3 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF48900.1 - 1.6e-11 43.7 23.9 0.2 12.3 0.1 9.1 7 3 3 10 10 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCF48900.1 - 3.6e-10 39.2 2.3 0.12 12.5 0.0 7.5 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF48900.1 - 1.1e-09 38.4 14.4 0.021 15.1 0.3 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCF48900.1 - 4.3e-06 26.4 14.5 0.0065 16.2 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCF48900.1 - 2.3e-05 24.5 13.8 5.8 7.5 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCF48900.1 - 0.0017 18.1 7.7 9.6 6.2 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Mito_carr PF00153.22 CCF48901.1 - 2.2e-58 193.9 8.6 1.8e-20 72.4 0.2 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein Gly-zipper_OmpA PF13436.1 CCF48901.1 - 1.4 8.5 11.9 0.42 10.2 4.1 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain RVT_2 PF07727.9 CCF48902.1 - 6.1e-17 61.4 0.0 3.1e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-Hacid_dh_C PF02826.14 CCF48903.1 - 4.6e-42 143.1 0.0 7.4e-41 139.2 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF48903.1 - 1.6e-26 92.3 0.0 2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCF48903.1 - 0.00031 20.6 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCF48903.1 - 0.062 13.7 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 CCF48904.1 - 7.6e-14 51.2 0.5 6e-12 45.0 0.1 2.4 2 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 CCF48904.1 - 9.4e-11 41.5 0.1 1.9e-10 40.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCF48904.1 - 4.8e-08 32.0 0.0 9.5e-08 31.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCF48904.1 - 0.0073 16.2 0.4 0.22 11.4 0.2 2.8 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CCF48904.1 - 0.0099 15.1 0.0 0.098 11.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 CCF48904.1 - 0.055 13.1 0.2 0.82 9.3 0.2 2.7 2 1 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 CCF48904.1 - 0.067 12.0 0.0 0.24 10.2 0.0 1.9 3 0 0 3 3 3 0 RmlD substrate binding domain E1-E2_ATPase PF00122.15 CCF48905.1 - 4.8e-23 81.4 4.5 5.1e-23 81.3 0.1 2.8 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CCF48905.1 - 7e-23 81.7 0.1 1.3e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF48905.1 - 1.5e-17 64.7 1.5 5.9e-16 59.5 0.1 3.7 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 CCF48905.1 - 3.9e-08 33.1 0.0 1.9e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 CCF48905.1 - 2.2e-05 24.3 0.0 7.2e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCF48905.1 - 0.0001 21.7 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Sugar_tr PF00083.19 CCF48906.1 - 3.3e-86 289.6 21.9 3.9e-86 289.4 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF48906.1 - 1.4e-20 73.3 15.6 1.4e-20 73.3 10.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.6 CCF48906.1 - 1.3 8.2 8.0 0.64 9.2 3.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Glyco_hydro_15 PF00723.16 CCF48907.1 - 1.1e-78 264.7 0.2 1.8e-78 264.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Abhydrolase_6 PF12697.2 CCF48908.1 - 5.7e-31 108.1 0.0 8e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48908.1 - 3.4e-10 39.8 0.0 8.4e-10 38.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF48908.1 - 3.8e-09 36.4 0.0 0.00012 21.7 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCF48908.1 - 0.0018 18.0 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CCF48908.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein QueF PF14489.1 CCF48908.1 - 0.012 15.4 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 QueF-like protein Rad60-SLD_2 PF13881.1 CCF48909.1 - 3.4e-13 49.4 3.1 6.1e-13 48.6 0.0 2.5 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like WD40 PF00400.27 CCF48910.1 - 1.2e-25 88.3 0.7 1.8e-07 30.7 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat PH PF00169.24 CCF48911.1 - 2.4e-06 27.7 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCF48911.1 - 0.003 17.8 0.2 0.012 15.8 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain GATA PF00320.22 CCF48912.1 - 5.1e-12 44.9 3.3 9.7e-12 44.0 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger WLM PF08325.5 CCF48913.1 - 1.7e-47 161.7 6.6 4.2e-47 160.4 1.1 2.7 2 1 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 CCF48913.1 - 1e-05 24.5 3.4 1.9e-05 23.6 2.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 CCF48913.1 - 0.0059 16.4 0.1 0.02 14.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function DUF45 Vps16_N PF04841.8 CCF48914.1 - 3e-68 230.2 0.0 9.2e-44 149.5 0.0 3.2 3 0 0 3 3 3 3 Vps16, N-terminal region Vps16_C PF04840.7 CCF48914.1 - 1.2e-67 228.1 4.6 1.5e-44 152.2 2.3 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region VWA_3 PF13768.1 CCF48914.1 - 0.089 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF1168 PF06658.7 CCF48915.1 - 1.4e-41 141.2 19.4 2.1e-41 140.7 13.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) HemX PF04375.9 CCF48915.1 - 0.13 10.8 5.7 0.18 10.4 3.9 1.2 1 0 0 1 1 1 0 HemX CENP-N PF05238.8 CCF48915.1 - 0.37 9.7 10.2 0.43 9.5 7.1 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Abhydrolase_3 PF07859.8 CCF48916.1 - 4.8e-25 88.3 0.0 8.7e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF48916.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 CCF48916.1 - 1.8e-05 23.5 0.0 2.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) UQ_con PF00179.21 CCF48917.1 - 4.1e-24 84.6 0.0 5.5e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ras PF00071.17 CCF48918.1 - 6.6e-46 155.6 0.0 8.2e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF48918.1 - 3.5e-16 59.7 0.0 4.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF48918.1 - 1.8e-07 30.5 0.0 2.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF48918.1 - 0.054 12.6 0.0 0.087 11.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF48918.1 - 0.057 12.8 0.0 0.52 9.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCF48918.1 - 0.091 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCF48918.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Helicase_C_3 PF13625.1 CCF48919.1 - 1.2e-27 96.1 0.0 3.3e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF48919.1 - 6.9e-15 55.3 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCF48919.1 - 7.2e-13 47.9 0.1 1.2e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF48919.1 - 6.2e-10 38.7 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF48919.1 - 1.1e-07 31.4 0.6 2.1e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Methyltransf_23 PF13489.1 CCF48919.1 - 0.055 13.1 0.0 3 7.5 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain GST_N PF02798.15 CCF48920.1 - 2.8e-12 46.6 0.0 6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF48920.1 - 9e-12 44.8 0.0 1.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCF48920.1 - 1.3e-11 44.4 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L5_C PF00673.16 CCF48921.1 - 1.3e-22 79.3 0.0 1.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCF48921.1 - 9.3e-20 70.1 0.0 2e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 DEAD PF00270.24 CCF48923.1 - 2.3e-44 150.8 0.0 2.3e-43 147.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF48923.1 - 8.6e-28 96.0 0.1 1.7e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF48923.1 - 0.0032 17.3 0.0 0.0089 15.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCF48923.1 - 0.059 11.7 0.0 0.1 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) ABC_membrane_2 PF06472.10 CCF48924.1 - 3.9e-98 328.0 7.4 4.4e-97 324.5 2.9 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCF48924.1 - 1.4e-15 57.7 0.0 7.6e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 CCF48924.1 - 0.0088 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCF48924.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CCF48924.1 - 0.017 14.2 0.2 0.039 12.9 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCF48924.1 - 0.017 15.9 0.0 0.065 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCF48924.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CCF48924.1 - 0.041 13.8 0.2 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCF48924.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCF48924.1 - 0.076 13.3 0.9 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCF48924.1 - 0.078 12.5 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 CCF48924.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 CCF48924.1 - 0.12 11.5 0.0 11 5.1 0.0 2.2 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Ribosomal_L33 PF00471.15 CCF48927.1 - 1.3e-13 50.8 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Peptidase_S10 PF00450.17 CCF48928.1 - 1.5e-96 324.1 5.3 2.7e-96 323.2 3.7 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase rve PF00665.21 CCF48930.1 - 3.9e-07 30.2 0.0 5.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain hDGE_amylase PF14701.1 CCF48933.1 - 6.3e-163 542.5 0.0 8.4e-163 542.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CCF48933.1 - 1e-111 373.2 0.0 1.7e-111 372.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CCF48933.1 - 1.3e-79 267.1 0.0 2.1e-79 266.4 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CCF48933.1 - 1.8e-20 72.5 0.1 4.4e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CCF48933.1 - 0.0094 15.3 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Ran_BP1 PF00638.13 CCF48934.1 - 2.1e-20 73.0 2.0 2.6e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain vATP-synt_E PF01991.13 CCF48935.1 - 1e-57 194.6 18.8 1.2e-57 194.3 13.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit eIF3g PF12353.3 CCF48936.1 - 9.4e-44 148.4 4.8 1.3e-43 147.9 3.4 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCF48936.1 - 3.5e-17 61.7 0.1 7.3e-17 60.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF48936.1 - 8.9e-14 51.2 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF48936.1 - 3.6e-08 33.1 0.0 1.1e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF48936.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Limkain b1 DHHW PF14286.1 CCF48936.1 - 0.18 11.0 0.1 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Ribonucleas_3_3 PF14622.1 CCF48937.1 - 6e-31 107.0 0.0 1.1e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCF48937.1 - 3.9e-05 24.0 0.0 0.00021 21.7 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain PAP1 PF08601.5 CCF48937.1 - 1.3 8.6 7.5 1.9 8.0 5.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 HhH-GPD PF00730.20 CCF48938.1 - 2.8e-19 69.4 0.0 7.7e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CCF48938.1 - 1.4e-13 50.2 0.1 1.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 NUDIX domain EndIII_4Fe-2S PF10576.4 CCF48938.1 - 0.0023 18.0 9.8 0.0023 18.0 6.8 2.6 3 0 0 3 3 3 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 CCF48938.1 - 0.0034 16.9 0.1 0.0086 15.7 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Rota_NS35 PF02509.9 CCF48938.1 - 0.099 11.3 0.2 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 NDUF_B8 PF05821.6 CCF48940.1 - 6.6e-09 35.6 0.0 9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Metallophos PF00149.23 CCF48941.1 - 1.2e-42 145.6 1.1 1.5e-42 145.2 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ELO PF01151.13 CCF48942.1 - 3.8e-60 203.2 15.6 3.8e-60 203.2 10.8 1.5 2 0 0 2 2 2 1 GNS1/SUR4 family Cpn60_TCP1 PF00118.19 CCF48943.1 - 2.1e-144 481.7 0.5 2.4e-144 481.5 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Collagen PF01391.13 CCF48944.1 - 0.0015 18.0 4.2 0.0039 16.7 2.9 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF448 PF04296.8 CCF48944.1 - 0.035 13.7 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF448) Fes1 PF08609.5 CCF48945.1 - 1.6e-19 70.1 0.2 4.6e-19 68.7 0.1 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CCF48945.1 - 1.4e-07 31.6 1.7 1.7e-05 25.0 0.2 2.3 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 CCF48945.1 - 1.4e-06 27.8 0.1 0.0051 16.5 0.0 3.1 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CCF48945.1 - 0.0016 18.3 0.1 5.1 7.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 CCF48945.1 - 0.0062 16.9 0.9 0.048 14.1 0.0 2.8 2 1 1 3 3 3 1 HEAT-like repeat DUF1180 PF06679.7 CCF48945.1 - 0.074 12.9 1.8 0.15 11.9 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cnd1 PF12717.2 CCF48945.1 - 0.082 12.7 0.3 16 5.2 0.0 2.6 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.3 CCF48945.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) Adaptin_N PF01602.15 CCF48945.1 - 0.16 10.2 0.5 6 5.0 0.1 2.1 1 1 1 2 2 2 0 Adaptin N terminal region zf-RING_2 PF13639.1 CCF48946.1 - 1.2e-11 44.2 9.2 1.2e-11 44.2 6.4 2.0 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 CCF48946.1 - 1.4e-10 41.1 5.8 3.5e-10 39.8 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCF48946.1 - 1.2e-06 28.0 7.3 2.9e-06 26.8 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF48946.1 - 3.6e-06 26.5 8.5 8.7e-06 25.3 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCF48946.1 - 6.3e-06 25.7 10.7 1.4e-05 24.6 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF48946.1 - 9.9e-06 25.4 10.2 9.9e-06 25.4 7.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF48946.1 - 3.2e-05 23.6 4.5 7.7e-05 22.4 3.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CCF48946.1 - 0.12 12.4 11.0 0.13 12.3 6.6 1.9 2 0 0 2 2 2 0 RING-variant domain PHD PF00628.24 CCF48946.1 - 0.13 11.9 8.3 0.34 10.6 5.8 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 CCF48946.1 - 0.81 9.3 9.2 2.1 7.9 6.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CCF48946.1 - 1 9.3 9.2 1.1 9.2 4.9 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain PRP3 PF08572.5 CCF48948.1 - 1.8e-63 213.9 9.9 1.8e-63 213.9 6.8 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCF48948.1 - 1.3e-31 108.9 0.0 3.5e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Serglycin PF04360.7 CCF48948.1 - 0.065 12.9 2.6 0.056 13.1 0.5 1.8 1 1 0 1 1 1 0 Serglycin PAPS_reduct PF01507.14 CCF48949.1 - 1.1e-21 77.4 0.0 7.2e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Prothymosin PF03247.9 CCF48950.1 - 0.0092 16.1 23.8 0.024 14.7 16.5 1.7 1 0 0 1 1 1 1 Prothymosin/parathymosin family VID27 PF08553.5 CCF48950.1 - 4.5 5.3 12.2 8.9 4.3 8.5 1.4 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nucleoplasmin PF03066.10 CCF48950.1 - 4.9 6.6 21.8 65 3.0 0.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin PAT1 PF09770.4 CCF48951.1 - 1.8e-197 658.2 26.8 1.1e-196 655.6 18.6 1.8 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sec1 PF00995.18 CCF48952.1 - 1.2e-157 525.9 0.0 1.8e-157 525.4 0.0 1.2 1 0 0 1 1 1 1 Sec1 family NIF PF03031.13 CCF48953.1 - 1.7e-49 167.5 0.0 4.2e-49 166.2 0.0 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Neisseria_TspB PF05616.8 CCF48954.1 - 4.8 5.4 6.9 6.5 4.9 4.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SKI PF01202.17 CCF48955.1 - 6.8e-12 45.5 0.1 8.7e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 CCF48955.1 - 1.7e-07 31.1 0.1 1.2e-05 25.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF48955.1 - 5.9e-07 30.3 0.0 3.1e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCF48955.1 - 3.3e-05 24.1 0.5 0.015 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 CCF48955.1 - 0.0026 17.7 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_16 PF13191.1 CCF48955.1 - 0.0029 17.6 0.3 0.017 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCF48955.1 - 0.0053 16.8 2.0 0.79 9.8 0.1 3.0 2 1 0 3 3 3 1 AAA domain APS_kinase PF01583.15 CCF48955.1 - 0.0072 15.9 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.1 CCF48955.1 - 0.0086 15.5 1.1 0.016 14.7 0.8 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 CCF48955.1 - 0.025 13.7 0.1 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IL5 PF02025.10 CCF48955.1 - 0.046 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Interleukin 5 Zeta_toxin PF06414.7 CCF48955.1 - 0.049 12.7 0.3 0.13 11.3 0.0 1.8 2 1 1 3 3 3 0 Zeta toxin CoaE PF01121.15 CCF48955.1 - 0.08 12.3 0.4 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Dephospho-CoA kinase ETF_alpha PF00766.14 CCF48955.1 - 0.11 12.1 0.7 7.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain ABC_tran PF00005.22 CCF48955.1 - 0.12 12.6 0.5 0.2 11.9 0.4 1.9 1 1 0 1 1 1 0 ABC transporter Ribosomal_L23 PF00276.15 CCF48956.1 - 1.7e-07 31.0 0.0 4.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 Pkinase PF00069.20 CCF48957.1 - 4e-62 209.7 0.0 5.1e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF48957.1 - 8.4e-34 116.8 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF48957.1 - 1.6e-07 30.5 0.0 3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF48957.1 - 0.00019 21.2 0.5 0.00041 20.1 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCF48957.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Histidinol_dh PF00815.15 CCF48958.1 - 5e-164 545.8 5.3 2.2e-145 484.4 2.2 3.1 3 0 0 3 3 3 2 Histidinol dehydrogenase PRA-CH PF01502.13 CCF48958.1 - 8.8e-23 79.7 0.2 1.6e-22 78.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CCF48958.1 - 1.2e-09 38.2 0.1 3.5e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 CCF48958.1 - 0.027 14.4 0.1 0.06 13.2 0.1 1.6 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Peptidase_S10 PF00450.17 CCF48959.1 - 9.1e-94 314.9 0.0 1.5e-93 314.2 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCF48959.1 - 0.00052 19.9 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 CCF48960.1 - 9e-34 116.2 0.0 1.4e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF48960.1 - 1.5e-10 41.0 1.1 3.5e-10 39.8 0.8 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Collagen PF01391.13 CCF48961.1 - 1.8e-07 30.5 34.7 3.8e-06 26.3 24.1 2.7 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) NUDIX PF00293.23 CCF48963.1 - 2e-08 33.9 0.0 4.7e-07 29.5 0.0 2.8 1 1 1 2 2 2 1 NUDIX domain Exo_endo_phos PF03372.18 CCF48964.1 - 1.6e-24 87.2 0.0 3.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 CCF48964.1 - 8.1e-05 22.3 1.2 0.014 15.2 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat CN_hydrolase PF00795.17 CCF48965.1 - 8.6e-26 90.4 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SRP19 PF01922.12 CCF48967.1 - 5.7e-18 65.2 0.0 1.3e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein DUF3123 PF11321.3 CCF48967.1 - 1.1 9.6 5.0 2.6 8.3 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) PolyA_pol PF01743.15 CCF48968.1 - 4.9e-21 75.2 0.0 9.2e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCF48968.1 - 1.6e-05 24.3 0.2 5.2e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Y_phosphatase2 PF03162.8 CCF48969.1 - 2.8e-58 195.9 0.0 4.4e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCF48969.1 - 1e-07 32.3 0.0 3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCF48969.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF48969.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF4544 PF15077.1 CCF48969.1 - 0.27 10.6 0.8 0.47 9.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF2462 PF09495.5 CCF48970.1 - 4.8e-20 72.0 11.2 4.8e-20 72.0 7.8 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Cnd2 PF05786.9 CCF48971.1 - 8.3e-142 474.2 0.2 8.3e-142 474.2 0.1 2.4 1 1 0 2 2 2 1 Condensin complex subunit 2 NDK PF00334.14 CCF48972.1 - 9.8e-33 112.8 0.0 1.4e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Spt20 PF12090.3 CCF48973.1 - 2.7e-37 127.8 0.0 2.7e-37 127.8 0.0 4.7 3 3 0 3 3 3 1 Spt20 family Hamartin PF04388.7 CCF48973.1 - 0.2 10.3 29.0 0.59 8.7 4.8 2.2 2 0 0 2 2 2 0 Hamartin protein Hid1 PF12722.2 CCF48973.1 - 0.69 7.5 35.0 0.67 7.5 7.7 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein BaxI_1 PF12811.2 CCF48973.1 - 1.4 8.0 10.0 3 6.9 6.9 1.5 1 0 0 1 1 1 0 Bax inhibitor 1 like adh_short PF00106.20 CCF48974.1 - 2.2e-24 86.2 0.0 1.2e-17 64.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCF48974.1 - 3e-14 53.3 0.0 6e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF48974.1 - 8.9e-07 28.7 0.1 6.3e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCF48974.1 - 0.0023 17.3 0.0 0.0057 16.1 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCF48974.1 - 0.022 14.5 0.1 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 CCF48974.1 - 0.086 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CDC14 PF08045.6 CCF48976.1 - 1.6e-05 24.1 0.0 0.00017 20.8 0.0 2.4 1 1 0 1 1 1 1 Cell division control protein 14, SIN component BRAP2 PF07576.7 CCF48977.1 - 1.3e-23 82.6 0.1 2.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CCF48977.1 - 6.6e-19 67.7 5.2 6.6e-19 67.7 3.6 2.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CCF48977.1 - 8.4e-09 35.1 10.3 8.4e-09 35.1 7.2 2.8 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCF48977.1 - 8.8e-05 22.0 8.8 8.8e-05 22.0 6.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF48977.1 - 0.0001 22.2 9.9 0.0001 22.2 6.8 2.5 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF48977.1 - 0.00054 20.0 6.3 0.00054 20.0 4.3 2.8 4 0 0 4 4 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCF48977.1 - 0.0011 18.6 4.4 0.0052 16.4 1.8 2.6 1 1 1 2 2 2 1 RING-type zinc-finger RRM_6 PF14259.1 CCF48977.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 CCF48977.1 - 0.046 13.2 5.8 0.12 11.9 4.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zip PF02535.17 CCF48977.1 - 0.073 12.0 5.7 0.054 12.5 2.5 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 CCF48977.1 - 0.097 11.5 21.7 0.19 10.5 15.1 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RRM_1 PF00076.17 CCF48977.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_GP20 PF06810.6 CCF48977.1 - 6 6.2 20.6 0.019 14.3 7.6 1.8 2 0 0 2 2 1 0 Phage minor structural protein GP20 Aldo_ket_red PF00248.16 CCF48978.1 - 3.9e-56 189.9 0.1 4.5e-56 189.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPP_enzyme_N PF02776.13 CCF48979.1 - 2.4e-34 118.2 0.0 4.4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCF48979.1 - 2.4e-27 95.3 0.0 6.9e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCF48979.1 - 2.6e-14 53.0 0.0 9.2e-14 51.2 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TauD PF02668.11 CCF48980.1 - 2.7e-51 174.7 0.1 3.7e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1644 PF07800.7 CCF48981.1 - 0.021 14.6 2.2 0.027 14.3 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Thymidylate_kin PF02223.12 CCF48981.1 - 0.031 13.6 1.3 0.034 13.5 0.9 1.1 1 0 0 1 1 1 0 Thymidylate kinase SHR3_chaperone PF08229.6 CCF48981.1 - 0.031 13.2 4.6 0.03 13.3 3.2 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 OATP PF03137.15 CCF48981.1 - 0.05 11.6 2.8 0.046 11.7 1.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FHIPEP PF00771.15 CCF48981.1 - 0.06 11.6 1.2 0.055 11.7 0.9 1.0 1 0 0 1 1 1 0 FHIPEP family AIF_C PF14721.1 CCF48981.1 - 0.082 13.1 1.7 0.081 13.1 1.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.10 CCF48981.1 - 0.09 11.4 3.8 0.086 11.5 2.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spt20 PF12090.3 CCF48981.1 - 0.098 11.9 9.3 0.1 11.9 6.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF1980 PF09323.5 CCF48981.1 - 0.098 12.3 2.2 0.1 12.3 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ETRAMP PF09716.5 CCF48981.1 - 0.11 12.4 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Hom_end_hint PF05203.11 CCF48981.1 - 0.14 11.8 3.3 0.15 11.7 2.3 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint Folate_carrier PF01770.13 CCF48981.1 - 0.14 10.5 6.3 0.16 10.4 4.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier Band_3_cyto PF07565.8 CCF48981.1 - 0.41 10.1 5.7 0.4 10.1 4.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4199 PF13858.1 CCF48981.1 - 0.89 9.4 3.0 0.88 9.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) UPF0560 PF10577.4 CCF48981.1 - 1.1 7.4 11.4 0.93 7.6 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF_4EBP PF05456.6 CCF48981.1 - 1.9 8.2 7.9 2.2 7.9 5.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF912 PF06024.7 CCF48981.1 - 2.2 8.3 5.7 2.5 8.1 3.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CCF48981.1 - 6.5 5.7 21.5 7.2 5.5 14.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CCF48981.1 - 6.8 6.3 17.8 7.2 6.2 12.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) G0-G1_switch_2 PF15103.1 CCF48981.1 - 7.8 6.7 7.6 9.5 6.5 5.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 DivIC PF04977.10 CCF48981.1 - 9 5.8 17.3 11 5.5 12.0 1.3 1 0 0 1 1 1 0 Septum formation initiator RXT2_N PF08595.6 CCF48983.1 - 0.099 12.4 0.8 0.11 12.2 0.5 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 CCF48983.1 - 0.91 9.7 7.2 1.2 9.3 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4140 PF13600.1 CCF48984.1 - 0.044 14.2 5.9 0.75 10.2 1.2 2.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 CCF48984.1 - 0.048 13.6 10.9 0.22 11.5 3.0 2.3 2 0 0 2 2 2 0 Up-regulated During Septation TP_methylase PF00590.15 CCF48985.1 - 1e-36 126.6 0.2 2.2e-36 125.5 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CCF48985.1 - 7.4e-11 42.2 0.0 9.8e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCF48985.1 - 4.5e-08 32.2 0.2 3.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCF48985.1 - 1.3e-05 24.0 0.1 2.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central LEAP-2 PF07359.6 CCF48985.1 - 0.02 14.5 0.0 0.086 12.5 0.0 2.1 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) COX17 PF05051.8 CCF48986.1 - 2.6e-16 59.3 7.6 4e-16 58.7 5.3 1.3 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 CCF48986.1 - 0.037 13.8 2.8 0.064 13.1 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) Peptidase_M16_C PF05193.16 CCF48987.1 - 2.2e-17 63.3 0.0 1.4e-10 41.1 0.0 2.9 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCF48987.1 - 5.7e-07 29.3 0.2 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF1478 PF07349.6 CCF48987.1 - 0.078 12.3 0.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) Sdh_cyt PF01127.17 CCF48988.1 - 2.7e-24 85.3 5.0 3.8e-24 84.8 3.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Exonuc_VII_L PF02601.10 CCF48989.1 - 0.063 12.4 18.6 0.12 11.5 9.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2524 PF10732.4 CCF48989.1 - 0.73 10.0 7.1 1 9.5 4.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DNA_pol_A PF00476.15 CCF48990.1 - 1.8e-88 296.7 0.0 2.8e-88 296.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_B_exo2 PF10108.4 CCF48990.1 - 0.07 12.6 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Urease_alpha PF00449.15 CCF48991.1 - 1.4e-54 183.4 0.4 2.6e-54 182.4 0.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 CCF48991.1 - 1.3e-50 172.9 1.2 2.4e-50 172.1 0.8 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_gamma PF00547.13 CCF48991.1 - 3.9e-39 132.6 0.1 9.1e-39 131.4 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 CCF48991.1 - 1.1e-35 121.5 0.1 4.1e-35 119.6 0.0 2.1 2 1 0 2 2 2 1 Urease beta subunit Amidohydro_5 PF13594.1 CCF48991.1 - 1.2e-05 25.0 4.4 5.7e-05 22.8 3.1 2.2 2 0 0 2 2 2 1 Amidohydrolase Flavin_Reduct PF01613.13 CCF48992.1 - 6.3e-31 107.3 0.1 6.3e-31 107.3 0.1 1.7 2 0 0 2 2 2 1 Flavin reductase like domain Abhydrolase_1 PF00561.15 CCF48993.1 - 5.1e-19 68.7 0.0 2.2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF48993.1 - 1.9e-11 44.2 4.0 3e-10 40.3 2.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF48993.1 - 0.00056 19.6 0.2 0.16 11.6 0.1 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 CCF48993.1 - 0.077 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase GAF_2 PF13185.1 CCF48994.1 - 0.03 14.8 0.3 1.6 9.1 0.0 2.2 2 0 0 2 2 2 0 GAF domain Seipin PF06775.9 CCF48995.1 - 1.6e-60 204.0 0.0 2.4e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Glyco_hydro_92 PF07971.7 CCF48997.1 - 5.9e-131 437.5 0.0 7e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Aldo_ket_red PF00248.16 CCF48998.1 - 1.8e-38 131.9 0.0 2.1e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TAP42 PF04177.7 CCF48999.1 - 2.2e-72 243.8 0.0 2.8e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 TAP42-like family DUF1492 PF07374.6 CCF49000.1 - 0.046 13.8 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Ribosomal_L10 PF00466.15 CCF49001.1 - 4e-26 90.8 0.0 8.4e-26 89.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CCF49001.1 - 1.3e-22 79.9 10.4 5.9e-22 77.8 6.4 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1021 PF06257.6 CCF49001.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) LIM PF00412.17 CCF49002.1 - 2.6e-11 43.3 39.8 0.00014 21.8 1.3 6.6 6 0 0 6 6 6 4 LIM domain Epimerase PF01370.16 CCF49003.1 - 2.3e-42 145.0 0.0 2.9e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCF49003.1 - 1.9e-25 88.5 0.0 3.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CCF49003.1 - 3.8e-12 45.5 0.0 9.1e-11 40.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCF49003.1 - 9e-11 41.1 0.0 2.1e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CCF49003.1 - 4.8e-09 35.5 0.0 7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCF49003.1 - 7.4e-08 31.6 0.0 4.8e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCF49003.1 - 7.8e-05 22.6 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCF49003.1 - 0.00011 22.2 0.0 0.0069 16.4 0.0 2.3 1 1 1 2 2 2 1 NADH(P)-binding KR PF08659.5 CCF49003.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 KR domain PrpF PF04303.8 CCF49004.1 - 5.1e-53 180.1 0.2 4.4e-34 117.8 0.1 3.2 2 1 0 2 2 2 2 PrpF protein DUF2791 PF10923.3 CCF49004.1 - 0.22 10.1 0.2 0.35 9.4 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Acyltransferase PF01553.16 CCF49005.1 - 3.5e-22 78.2 0.0 6.1e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NatB_MDM20 PF09797.4 CCF49007.1 - 1.2e-72 244.6 9.6 1.6e-72 244.2 5.1 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 CCF49007.1 - 8.9e-06 25.9 12.5 0.25 11.7 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49007.1 - 0.0065 17.1 6.2 0.034 14.8 0.2 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF49007.1 - 0.0088 16.6 5.6 2.7 8.8 0.1 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF1708 PF08101.6 CCF49008.1 - 1.8e-13 50.1 0.0 1.7e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CCF49008.1 - 5.2e-08 32.6 0.0 6.8e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 RhoGAP domain Pyridoxal_deC PF00282.14 CCF49009.1 - 2e-63 214.1 0.0 2.9e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCF49009.1 - 0.00043 19.1 0.0 0.00086 18.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF2613 PF11021.3 CCF49010.1 - 0.056 13.1 1.8 0.2 11.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF1510 PF07423.6 CCF49010.1 - 0.12 11.7 0.2 0.12 11.7 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1510) IncA PF04156.9 CCF49010.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 IncA protein DUF809 PF05663.6 CCF49010.1 - 1.8 8.5 6.1 4.3 7.2 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF809) MTHFR PF02219.12 CCF49011.1 - 2.4e-100 335.3 0.0 6.3e-83 278.1 0.0 2.1 2 0 0 2 2 2 2 Methylenetetrahydrofolate reductase PLDc_2 PF13091.1 CCF49012.1 - 3.1e-17 62.5 0.0 2.8e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain Dicty_REP PF05086.7 CCF49012.1 - 2.1 5.9 6.2 3.1 5.4 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cpn60_TCP1 PF00118.19 CCF49013.1 - 1.3e-156 522.0 2.6 1.4e-156 521.9 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nol1_Nop2_Fmu PF01189.12 CCF49015.1 - 1.8e-11 43.9 0.2 8.8e-07 28.5 0.0 2.6 3 0 0 3 3 3 2 NOL1/NOP2/sun family Pyrophosphatase PF00719.14 CCF49016.1 - 9.2e-53 177.8 0.2 1.2e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase COesterase PF00135.23 CCF49017.1 - 8.3e-91 305.3 0.0 1.1e-90 304.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF49017.1 - 2.7e-09 36.9 3.0 0.0006 19.4 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold OTU PF02338.14 CCF49018.1 - 4.2e-11 43.4 0.0 7.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_jaz PF12171.3 CCF49018.1 - 0.079 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_3 PF00933.16 CCF49019.1 - 9.7e-60 202.0 0.0 1.8e-43 148.6 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCF49019.1 - 1.5e-45 155.4 0.0 1.5e-44 152.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCF49019.1 - 1.9e-23 82.1 0.4 3.6e-23 81.2 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.19 CCF49020.1 - 3.7e-104 348.8 26.8 5.2e-104 348.3 18.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF49020.1 - 8.7e-28 97.0 34.9 7.2e-27 94.0 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CRA PF06589.6 CCF49020.1 - 1.2 8.4 2.9 1.2 8.4 0.2 2.0 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) FAD_binding_7 PF03441.9 CCF49021.1 - 2.3e-88 296.0 0.1 3.6e-88 295.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CCF49021.1 - 1.7e-41 141.7 0.0 3.1e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase YbjN PF10722.4 CCF49021.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative bacterial sensory transduction regulator Pribosyltran_N PF13793.1 CCF49022.1 - 6.2e-46 154.8 0.2 3.4e-45 152.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCF49022.1 - 1.9e-39 135.3 0.6 3.4e-32 111.6 0.2 2.6 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCF49022.1 - 3.1e-12 46.3 1.8 1.5e-11 44.0 0.3 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCF49022.1 - 0.071 12.3 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase Pil1 PF13805.1 CCF49023.1 - 2.4e-20 72.8 1.4 6e-20 71.5 1.0 1.6 1 0 0 1 1 1 1 Eisosome component PIL1 AAA_27 PF13514.1 CCF49023.1 - 0.023 12.4 4.9 0.034 11.8 3.4 1.1 1 0 0 1 1 1 0 AAA domain GrpE PF01025.14 CCF49023.1 - 0.024 14.1 0.8 0.048 13.2 0.6 1.5 1 0 0 1 1 1 0 GrpE TMF_TATA_bd PF12325.3 CCF49023.1 - 0.058 13.1 2.6 0.14 11.9 1.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 CCF49023.1 - 0.083 11.3 4.7 0.12 10.8 3.2 1.1 1 0 0 1 1 1 0 AAA domain Gp-FAR-1 PF05823.7 CCF49023.1 - 0.14 12.1 6.0 0.075 12.9 1.1 2.4 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Vps51 PF08700.6 CCF49023.1 - 0.16 11.8 1.3 0.41 10.5 0.9 1.7 1 0 0 1 1 1 0 Vps51/Vps67 CENP-Q PF13094.1 CCF49023.1 - 0.75 9.8 6.3 17 5.3 0.1 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 CCF49023.1 - 6.1 5.4 11.0 0.75 8.3 2.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein NIPSNAP PF07978.8 CCF49024.1 - 2.6e-36 123.6 0.6 2.3e-26 91.7 0.1 2.3 2 0 0 2 2 2 2 NIPSNAP Pyridoxal_deC PF00282.14 CCF49025.1 - 1.5e-97 326.4 0.0 7.3e-64 215.5 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain BCDHK_Adom3 PF10436.4 CCF49026.1 - 3.1e-45 153.6 0.0 4.7e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCF49026.1 - 4.8e-13 48.7 0.0 1.9e-11 43.6 0.0 2.3 1 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCF49026.1 - 3e-06 26.9 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Grp1_Fun34_YaaH PF01184.14 CCF49027.1 - 7.7e-16 58.0 11.0 9.6e-16 57.7 7.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CCF49029.1 - 7.9e-70 234.4 16.3 9.4e-70 234.1 11.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.20 CCF49030.1 - 4.1e-15 56.0 0.9 1.2e-14 54.5 0.6 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF49030.1 - 0.00016 21.5 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF49030.1 - 0.035 13.7 6.7 0.027 14.1 1.2 2.7 2 1 0 2 2 2 0 KR domain P12 PF12669.2 CCF49031.1 - 0.004 17.3 3.4 0.005 17.0 2.4 1.1 1 0 0 1 1 1 1 Virus attachment protein p12 family L6_membrane PF05805.7 CCF49031.1 - 0.079 12.4 0.6 0.088 12.3 0.4 1.0 1 0 0 1 1 1 0 L6 membrane protein AAA PF00004.24 CCF49032.1 - 2.3e-14 53.7 0.0 5.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF49032.1 - 6.9e-10 39.2 0.0 4.2e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCF49032.1 - 4e-07 30.2 0.0 9.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF49032.1 - 4.8e-05 23.0 0.0 0.00024 20.7 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CCF49032.1 - 0.0043 16.6 0.2 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCF49032.1 - 0.018 14.7 0.0 0.055 13.1 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 CCF49032.1 - 0.032 13.7 0.0 0.094 12.2 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 CCF49032.1 - 0.042 12.8 0.1 0.089 11.7 0.0 1.5 2 0 0 2 2 2 0 PIF1-like helicase DUF2075 PF09848.4 CCF49032.1 - 0.05 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_transf_22 PF03901.12 CCF49033.1 - 2.1e-64 218.1 24.4 2.8e-63 214.3 15.5 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family DUF3816 PF12822.2 CCF49033.1 - 3.2 7.5 11.6 0.46 10.3 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) SPC25 PF06703.6 CCF49034.1 - 1.3e-41 141.8 0.0 1.6e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pam17 PF08566.5 CCF49034.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 RRM_1 PF00076.17 CCF49035.1 - 5.4e-12 45.1 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49035.1 - 1.9e-11 43.7 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-4B PF06273.6 CCF49035.1 - 0.0057 15.4 45.1 0.02 13.6 30.2 2.5 1 1 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B DUF2417 PF10329.4 CCF49036.1 - 1e-10 41.4 0.4 1.8e-10 40.6 0.3 1.4 1 1 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CCF49036.1 - 2.5e-05 24.2 1.3 4e-05 23.5 0.3 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Nuc_sug_transp PF04142.10 CCF49037.1 - 2.4e-67 226.5 1.3 5.3e-67 225.4 0.9 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CCF49037.1 - 8.3e-08 31.4 7.3 7.7e-05 21.7 0.2 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 CCF49037.1 - 0.00011 22.2 0.7 0.00011 22.2 0.5 2.7 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CCF49037.1 - 0.00015 21.9 1.0 0.00015 21.9 0.7 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 CCF49037.1 - 0.00023 20.8 14.0 0.0044 16.6 0.1 3.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family zf-C2H2 PF00096.21 CCF49038.1 - 6.4e-06 26.1 2.6 0.07 13.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCF49038.1 - 1.5e-05 24.9 3.9 0.00041 20.4 0.3 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCF49038.1 - 0.0012 19.0 3.5 0.016 15.4 0.1 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CCF49038.1 - 0.0021 18.1 1.2 0.28 11.3 0.9 2.2 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CCF49038.1 - 0.15 12.0 1.7 0.42 10.5 0.0 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF49038.1 - 3.2 8.2 8.0 0.94 9.8 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Rrn6 PF10214.4 CCF49040.1 - 4.9e-07 28.2 21.4 0.00023 19.4 7.4 3.2 2 1 1 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Peptidase_M16 PF00675.15 CCF49042.1 - 4.3e-08 33.0 0.4 0.011 15.5 0.0 3.0 1 1 2 3 3 3 2 Insulinase (Peptidase family M16) Hydrolase_like2 PF13246.1 CCF49042.1 - 0.011 15.6 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Vps16_C PF04840.7 CCF49043.1 - 2e-05 23.7 0.0 3.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Vps16, C-terminal region MtrD PF04207.7 CCF49045.1 - 0.03 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Peptidase_M36 PF02128.10 CCF49046.1 - 1.1e-125 419.4 6.2 6.2e-125 416.9 3.4 2.7 2 1 0 2 2 2 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 CCF49046.1 - 1.2e-08 34.2 0.0 2.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif cwf21 PF08312.7 CCF49046.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 cwf21 domain Peptidase_M4_C PF02868.10 CCF49046.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Nup188 PF10487.4 CCF49047.1 - 1.7e-13 49.4 0.1 5e-06 24.7 0.0 3.1 3 0 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 Abhydrolase_5 PF12695.2 CCF49048.1 - 0.027 14.2 0.0 0.12 12.1 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family ThiF PF00899.16 CCF49049.1 - 2.6e-39 134.1 0.0 1e-38 132.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CCF49049.1 - 8.3e-26 89.3 0.1 1.7e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 CCF49049.1 - 3.1e-21 74.9 0.0 4.8e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 CCF49049.1 - 1.2e-19 69.4 1.2 2.4e-19 68.4 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CCF49049.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 CCF49049.1 - 0.0017 17.9 0.2 0.0099 15.4 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Gmx_para_CXXCG PF09535.5 CCF49049.1 - 0.043 12.7 0.1 1.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Cellulase PF00150.13 CCF49050.1 - 1e-16 61.0 4.2 2.4e-16 59.7 2.9 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PI3_PI4_kinase PF00454.22 CCF49051.1 - 7.7e-35 120.4 0.2 6.7e-34 117.3 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCF49051.1 - 1e-23 83.4 0.6 2e-23 82.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 CCF49051.1 - 0.0058 16.5 0.1 0.072 13.0 0.0 2.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Ras PF00071.17 CCF49052.1 - 7.6e-60 200.9 1.0 9.9e-60 200.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF49052.1 - 4e-21 75.7 0.2 8.7e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCF49052.1 - 4.7e-16 58.5 0.2 6.2e-16 58.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF49052.1 - 3.5e-08 33.0 0.2 1.6e-07 30.9 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCF49052.1 - 4.8e-06 25.9 0.1 6.9e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCF49052.1 - 5.6e-06 25.6 0.4 7e-06 25.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF49052.1 - 1.7e-05 24.7 0.1 4.5e-05 23.3 0.1 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF49052.1 - 0.0036 16.6 0.0 0.19 10.9 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.1 CCF49052.1 - 0.021 14.7 0.1 1.3 8.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCF49052.1 - 0.026 14.6 0.0 1.6 8.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 CCF49052.1 - 0.029 14.0 0.2 3.1 7.4 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCF49052.1 - 0.036 13.8 0.1 3.3 7.5 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 CCF49052.1 - 0.098 12.3 0.1 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase Transket_pyr PF02779.19 CCF49053.1 - 1.3e-44 151.8 0.0 2.3e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCF49053.1 - 1.7e-37 128.1 0.2 3.8e-37 126.9 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF900 PF05990.7 CCF49053.1 - 0.037 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CK_II_beta PF01214.13 CCF49054.1 - 1.3e-71 239.8 0.0 1.8e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PNP_UDP_1 PF01048.15 CCF49055.1 - 1e-31 109.7 0.0 2.3e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily G-gamma PF00631.17 CCF49057.1 - 4.4e-26 90.4 0.0 4.8e-26 90.2 0.0 1.0 1 0 0 1 1 1 1 GGL domain Iso_dh PF00180.15 CCF49058.1 - 4.2e-73 246.2 0.0 5e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.15 CCF49059.1 - 2.7e-73 246.9 0.0 3.1e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PSD1 PF07587.6 CCF49060.1 - 0.0013 18.1 2.5 0.3 10.4 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1553) SpaB_C PF14028.1 CCF49060.1 - 0.25 10.8 4.3 0.43 10.0 3.0 1.4 1 1 0 1 1 1 0 SpaB C-terminal domain WHIM3 PF15614.1 CCF49060.1 - 6.4 6.6 6.5 4.4 7.1 1.5 2.5 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 Chitin_synth_2 PF03142.10 CCF49061.1 - 2.4e-20 72.4 0.6 9.3e-18 63.8 0.1 2.7 2 2 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCF49061.1 - 5e-07 29.6 5.6 5e-07 29.6 3.9 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF49061.1 - 0.00023 21.0 0.9 0.001 18.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UDPG_MGDP_dh_N PF03721.9 CCF49062.1 - 9.6e-22 77.2 0.0 3.9e-20 72.0 0.0 2.6 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 CCF49062.1 - 2e-17 63.1 0.0 5.8e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 CCF49062.1 - 3.1e-05 24.0 0.2 0.0002 21.4 0.0 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_18 PF12847.2 CCF49062.1 - 0.00068 20.1 0.0 0.0033 17.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_2 PF03446.10 CCF49062.1 - 0.0008 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 CCF49062.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_26 PF13659.1 CCF49062.1 - 0.015 15.3 0.0 0.053 13.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain GFO_IDH_MocA PF01408.17 CCF49062.1 - 0.016 15.7 0.5 0.14 12.6 0.0 2.7 2 1 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 CCF49062.1 - 0.019 14.1 0.0 0.9 8.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 CCF49062.1 - 0.027 14.0 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Mucin PF01456.12 CCF49063.1 - 0.13 11.9 14.9 0.2 11.4 10.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Cutinase PF01083.17 CCF49064.1 - 1.9e-31 109.1 2.2 1.9e-31 109.1 1.5 1.8 2 0 0 2 2 2 1 Cutinase Thioesterase PF00975.15 CCF49064.1 - 0.019 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain YchF-GTPase_C PF06071.8 CCF49066.1 - 5.4e-32 109.4 0.5 5.4e-32 109.4 0.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCF49066.1 - 4.3e-14 52.4 0.1 3.1e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF49066.1 - 2.4e-05 23.6 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CCF49066.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 TGS domain BetaGal_dom3 PF13363.1 CCF49066.1 - 0.027 13.8 0.3 0.088 12.2 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 AAA_14 PF13173.1 CCF49066.1 - 0.093 12.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pro-kuma_activ PF09286.6 CCF49067.1 - 2.3e-34 118.4 0.1 5.2e-34 117.3 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 CCF49067.1 - 1.2e-12 47.6 0.5 6.1e-12 45.2 0.0 2.0 1 1 1 2 2 2 1 Subtilase family TMPIT PF07851.8 CCF49069.1 - 0.21 10.5 3.1 0.49 9.4 2.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein UCR_UQCRX_QCR9 PF05365.7 CCF49070.1 - 6e-29 99.4 3.0 6.6e-29 99.3 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like YqzE PF14038.1 CCF49072.1 - 0.0068 16.1 2.0 0.038 13.7 0.8 2.2 2 0 0 2 2 2 1 YqzE-like protein DEAD PF00270.24 CCF49073.1 - 9.9e-43 145.5 0.3 7e-42 142.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF49073.1 - 9.2e-29 99.1 0.2 2.5e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CCF49073.1 - 0.019 13.3 0.0 0.082 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 CCF49073.1 - 0.031 14.1 0.1 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCF49073.1 - 0.11 12.2 0.3 0.31 10.8 0.2 1.7 1 1 0 1 1 1 0 Part of AAA domain DUF3449 PF11931.3 CCF49074.1 - 1.3e-66 223.8 0.7 2.9e-66 222.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 CCF49074.1 - 3.8e-10 39.1 0.1 8.6e-10 37.9 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 CCF49074.1 - 8.6e-05 22.5 8.5 0.00034 20.6 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF49074.1 - 0.001 19.1 5.6 0.0023 18.0 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCF49074.1 - 0.0036 17.3 0.8 3.3 7.8 0.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) RNase_HII PF01351.13 CCF49075.1 - 1.3e-42 145.6 0.0 2.3e-38 131.8 0.0 2.5 1 1 0 2 2 2 2 Ribonuclease HII DNA_pol_A_exo1 PF01612.15 CCF49076.1 - 7.7e-42 142.7 0.5 1.3e-41 141.9 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CCF49076.1 - 1.7e-11 44.2 0.9 1.8e-06 28.1 0.1 2.7 1 1 1 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.18 CCF49076.1 - 3.2e-11 42.7 0.1 8.1e-11 41.4 0.1 1.8 1 0 0 1 1 1 1 HRDC domain Glyco_hydro_17 PF00332.13 CCF49077.1 - 6.2e-11 41.9 0.9 7.5e-09 35.0 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Ribosomal_S11 PF00411.14 CCF49078.1 - 4.3e-12 46.1 0.3 1e-11 44.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 DUF92 PF01940.11 CCF49079.1 - 1.4e-54 184.6 4.6 2.4e-52 177.3 3.2 2.0 1 1 0 1 1 1 1 Integral membrane protein DUF92 COG6 PF06419.6 CCF49080.1 - 4.8e-120 401.5 0.0 2.7e-94 316.5 0.0 2.1 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 PTR2 PF00854.16 CCF49082.1 - 5.3e-40 137.3 16.9 6.6e-39 133.7 11.7 2.1 1 1 0 1 1 1 1 POT family Cation_efflux PF01545.16 CCF49083.1 - 1.3e-60 204.9 10.3 2.9e-60 203.7 3.2 3.2 3 0 0 3 3 3 1 Cation efflux family EF-hand_1 PF00036.27 CCF49084.1 - 3.6e-21 72.7 0.1 9.7e-06 24.5 0.0 4.3 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CCF49084.1 - 9.6e-17 59.3 0.0 5.1e-06 25.9 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CCF49084.1 - 9.5e-16 56.3 0.0 0.00069 18.8 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CCF49084.1 - 1.5e-15 57.0 0.0 5.6e-06 26.4 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCF49084.1 - 2.2e-14 52.8 0.4 2.3e-08 33.5 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair Extensin_2 PF04554.8 CCF49084.1 - 0.011 15.5 16.0 0.011 15.5 11.1 2.6 1 1 1 2 2 2 0 Extensin-like region PEHE PF15275.1 CCF49085.1 - 8.3e-05 23.0 2.2 8.3e-05 23.0 1.5 5.3 4 1 1 5 5 5 1 PEHE domain SAS4 PF15460.1 CCF49085.1 - 0.00031 20.5 0.5 0.0007 19.4 0.3 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Exo_endo_phos PF03372.18 CCF49087.1 - 2.6e-19 70.1 0.0 3.5e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCF49087.1 - 6.1e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Mad3_BUB1_I PF08311.7 CCF49088.1 - 1.2e-35 122.0 0.3 2.1e-35 121.2 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 CCF49088.1 - 1.1e-11 44.4 0.0 3.6e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF936 PF06075.7 CCF49089.1 - 9.6 4.9 16.4 11 4.7 11.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ELFV_dehydrog PF00208.16 CCF49090.1 - 1.1e-48 165.9 0.0 1.7e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CCF49090.1 - 4.9e-24 83.9 0.0 1e-16 59.6 0.0 2.4 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CCF49090.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Herpes_gE PF02480.11 CCF49091.1 - 3.1e-05 22.4 0.0 3.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 CCF49091.1 - 0.00098 19.3 0.4 0.0016 18.6 0.3 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator PAG PF15347.1 CCF49091.1 - 0.018 14.1 0.2 0.021 13.9 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched DUF3357 PF11837.3 CCF49091.1 - 0.023 14.5 3.7 0.047 13.5 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) CD34_antigen PF06365.7 CCF49091.1 - 0.043 13.4 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 CCF49091.1 - 0.049 14.0 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.6 CCF49091.1 - 0.053 13.1 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein SIT PF15330.1 CCF49091.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 CCF49091.1 - 0.06 13.0 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Git3 PF11710.3 CCF49091.1 - 0.082 12.4 0.6 0.11 12.0 0.4 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Ctr PF04145.10 CCF49091.1 - 0.1 12.6 0.2 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family F-box-like PF12937.2 CCF49092.1 - 0.001 18.7 0.6 0.0027 17.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF49092.1 - 0.02 14.5 0.6 0.058 13.0 0.1 2.0 2 0 0 2 2 2 0 F-box domain Proteasome PF00227.21 CCF49093.1 - 1.3e-56 190.9 0.4 1.6e-56 190.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF49093.1 - 1.4e-14 53.0 0.0 2.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Abhydrolase_5 PF12695.2 CCF49094.1 - 2.2e-05 24.2 0.0 4.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF49094.1 - 6.7e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CCF49094.1 - 0.00022 20.8 0.0 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 CCF49094.1 - 0.00087 18.9 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 CCF49094.1 - 0.0058 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.10 CCF49094.1 - 0.025 13.5 0.0 0.087 11.7 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF2974 PF11187.3 CCF49094.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-CCHC PF00098.18 CCF49095.1 - 0.22 11.4 5.3 0.39 10.7 3.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Dioxygenase_C PF00775.16 CCF49096.1 - 1.1e-09 37.8 1.9 3.7e-07 29.5 0.1 2.6 2 1 0 2 2 2 2 Dioxygenase Abhydrolase_6 PF12697.2 CCF49097.1 - 2.2e-31 109.4 2.7 4.3e-31 108.5 1.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF49097.1 - 8.9e-14 51.5 0.2 6.9e-13 48.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF49097.1 - 5.5e-12 45.6 0.2 1.2e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 CCF49097.1 - 4.9e-09 35.8 0.7 1.4e-08 34.4 0.5 1.8 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.16 CCF49097.1 - 2e-05 23.9 0.0 0.026 13.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.9 CCF49097.1 - 2.1e-05 23.1 0.0 4.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 CCF49097.1 - 0.00014 21.3 0.1 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 CCF49097.1 - 0.011 15.3 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CCF49097.1 - 0.034 13.4 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CCF49097.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Tannase PF07519.6 CCF49097.1 - 0.073 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Ribosomal_L22 PF00237.14 CCF49098.1 - 7.2e-29 99.8 0.1 1.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PAP_central PF04928.12 CCF49099.1 - 7.3e-105 349.3 0.0 1.1e-104 348.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCF49099.1 - 2.8e-48 163.3 0.0 4.6e-48 162.7 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCF49099.1 - 2.9e-09 37.1 0.0 7.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 CCF49099.1 - 0.094 10.2 0.1 0.15 9.6 0.1 1.2 1 0 0 1 1 1 0 Nrap protein DNA_methylase PF00145.12 CCF49100.1 - 9.7e-44 149.8 0.0 2.5e-43 148.4 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase ENTH PF01417.15 CCF49101.1 - 1.7e-44 150.7 0.1 2.5e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCF49101.1 - 9.6e-05 21.2 0.1 0.00014 20.7 0.1 1.2 1 0 0 1 1 1 1 ANTH domain DUF3542 PF12061.3 CCF49101.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3542) Peptidase_M16 PF00675.15 CCF49102.1 - 3.9e-56 188.9 0.2 8.9e-56 187.7 0.2 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCF49102.1 - 8.6e-43 146.1 0.0 8.4e-41 139.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain WD40 PF00400.27 CCF49103.1 - 4.8e-09 35.7 0.1 0.0004 20.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat SurE PF01975.12 CCF49104.1 - 1.8e-31 108.9 0.0 1.8e-31 108.9 0.0 2.1 2 1 0 2 2 2 1 Survival protein SurE Sucrose_synth PF00862.14 CCF49106.1 - 0.091 10.7 0.1 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase RRM_1 PF00076.17 CCF49107.1 - 6.3e-08 32.1 0.0 1.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.1 CCF49107.1 - 3.6e-07 30.2 0.1 3.6e-07 30.2 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CCF49107.1 - 4e-07 29.3 0.1 0.0073 16.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain RRM_6 PF14259.1 CCF49107.1 - 3.2e-06 27.0 0.0 7.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.27 CCF49107.1 - 1.4e-05 24.0 0.1 0.11 11.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CCF49107.1 - 0.0024 17.4 0.3 0.057 13.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair RRM_5 PF13893.1 CCF49107.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.1 CCF49107.1 - 0.016 14.5 0.3 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 EF hand RVT_2 PF07727.9 CCF49108.1 - 3.1e-65 219.5 0.0 4.6e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF49108.1 - 0.0004 19.9 1.0 0.0011 18.5 0.7 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 CCF49109.1 - 2.7e-06 27.1 0.0 4.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 CCF49109.1 - 5.6e-06 25.9 0.2 8.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CCF49109.1 - 7.4e-05 22.2 0.1 0.00016 21.2 0.0 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF1600 PF07667.6 CCF49109.1 - 0.008 16.2 0.3 0.013 15.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1600) Dopey_N PF04118.9 CCF49109.1 - 0.021 13.5 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Dopey, N-terminal Y1_Tnp PF01797.11 CCF49109.1 - 0.051 13.4 0.2 0.1 12.4 0.1 1.5 2 0 0 2 2 2 0 Transposase IS200 like DUF4517 PF15006.1 CCF49109.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) Aconitase PF00330.15 CCF49110.1 - 7.4e-186 618.1 0.1 8.8e-186 617.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCF49110.1 - 3.2e-45 153.4 0.0 6.2e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.18 CCF49111.1 - 2.2e-92 309.3 30.4 4.9e-51 173.7 13.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF49111.1 - 7.2e-67 223.9 0.0 3.4e-32 111.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF49111.1 - 1.1e-15 57.4 0.7 1.4e-05 24.4 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF49111.1 - 3.5e-12 46.9 0.0 0.061 13.2 0.0 4.3 3 1 1 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CCF49111.1 - 1.9e-10 39.9 2.6 0.0014 17.2 0.3 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCF49111.1 - 5.5e-09 35.4 0.4 0.00037 19.9 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCF49111.1 - 1.3e-07 32.4 0.0 0.0089 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF49111.1 - 1.6e-07 31.5 5.7 0.002 18.1 0.2 3.6 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 CCF49111.1 - 4.6e-06 26.4 2.5 0.075 12.9 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CCF49111.1 - 7e-06 26.2 1.8 0.22 11.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCF49111.1 - 2.3e-05 23.6 0.0 0.17 11.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_14 PF13173.1 CCF49111.1 - 8.3e-05 22.4 0.0 0.26 11.2 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CCF49111.1 - 0.0001 21.7 0.2 0.08 12.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 CCF49111.1 - 0.00065 19.9 3.4 2.2 8.4 0.2 3.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCF49111.1 - 0.00082 19.6 0.0 2.6 8.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 CCF49111.1 - 0.00095 19.5 0.0 1.2 9.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCF49111.1 - 0.0011 18.6 0.0 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCF49111.1 - 0.0024 17.7 2.0 2.3 8.0 0.3 3.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CCF49111.1 - 0.0041 16.2 0.0 3.6 6.6 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 CCF49111.1 - 0.0073 16.2 0.3 2 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCF49111.1 - 0.0088 14.9 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF87 PF01935.12 CCF49111.1 - 0.011 15.5 2.1 3.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CCF49111.1 - 0.013 14.9 0.8 7.4 5.9 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 CCF49111.1 - 0.024 14.3 0.5 7.8 6.1 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCF49111.1 - 0.033 13.0 0.1 3.8 6.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 CCF49111.1 - 0.046 13.2 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 CCF49111.1 - 0.062 13.4 1.4 5.2 7.2 0.0 3.6 4 0 0 4 4 3 0 RNA helicase Miro PF08477.8 CCF49111.1 - 0.072 13.5 0.0 10 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein APS_kinase PF01583.15 CCF49111.1 - 0.089 12.4 1.4 1.3 8.6 0.0 3.0 4 0 0 4 4 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 CCF49111.1 - 0.1 12.5 0.1 17 5.4 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 CCF49111.1 - 0.32 9.9 0.0 3.3 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 CCF49111.1 - 0.4 9.3 9.8 1.6 7.3 0.0 3.1 3 0 0 3 3 2 0 G-protein alpha subunit Dynamin_N PF00350.18 CCF49112.1 - 5.5e-17 62.0 3.5 1.5e-15 57.3 0.0 3.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 CCF49112.1 - 6.7e-10 38.9 0.0 7.7e-09 35.5 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF49112.1 - 1.9e-07 30.7 0.3 5e-06 26.0 0.2 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCF49112.1 - 0.00048 20.6 1.1 0.15 12.5 0.2 3.5 2 1 0 2 2 2 1 Miro-like protein cobW PF02492.14 CCF49112.1 - 0.001 18.5 0.3 0.0043 16.5 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CCF49112.1 - 0.0041 16.6 0.0 0.017 14.6 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain IIGP PF05049.8 CCF49112.1 - 0.0054 15.5 0.1 0.017 13.9 0.0 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 CCF49112.1 - 0.012 14.5 0.0 0.086 11.7 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF258 PF03193.11 CCF49112.1 - 0.041 13.0 0.1 0.23 10.6 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Exo_endo_phos_2 PF14529.1 CCF49112.1 - 0.043 13.4 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase HR1 PF02185.11 CCF49112.1 - 2.3 8.0 7.8 0.32 10.7 0.5 3.0 3 0 0 3 3 3 0 Hr1 repeat ABM PF03992.11 CCF49113.1 - 8.4e-06 25.7 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PQ-loop PF04193.9 CCF49114.1 - 1.4e-26 91.8 7.3 6.8e-14 51.1 0.0 3.0 4 0 0 4 4 4 2 PQ loop repeat DUF1301 PF06979.7 CCF49114.1 - 0.027 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) DUF3357 PF11837.3 CCF49114.1 - 0.069 13.0 0.1 1.2 8.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) PepSY_TM_2 PF13703.1 CCF49114.1 - 0.077 13.1 0.0 0.077 13.1 0.0 4.2 6 1 0 6 6 6 0 PepSY-associated TM helix NfeD PF01957.13 CCF49114.1 - 0.5 10.4 7.0 6.9 6.7 0.0 3.8 2 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding DUF1183 PF06682.7 CCF49115.1 - 3.6e-55 187.8 5.9 6.2e-55 187.0 4.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) CPSase_L_D2 PF02786.12 CCF49116.1 - 7.3e-53 178.9 0.0 1.7e-52 177.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 CCF49116.1 - 3.8e-43 147.5 0.2 8.4e-43 146.4 0.1 1.5 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_chain PF00289.17 CCF49116.1 - 2.1e-28 98.5 0.0 6.3e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCF49116.1 - 2e-25 88.8 0.0 4.3e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCF49116.1 - 4.4e-12 46.1 0.0 9.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCF49116.1 - 1.5e-11 43.7 4.1 4.1e-11 42.3 2.8 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCF49116.1 - 1.2e-09 37.4 0.0 0.00024 19.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CCF49116.1 - 8.8e-07 28.5 4.7 0.0015 18.1 0.2 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD PF00529.15 CCF49116.1 - 0.0015 17.8 5.0 0.0032 16.8 0.3 2.6 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 CCF49116.1 - 0.011 14.8 2.4 0.057 12.5 1.7 2.0 1 1 0 1 1 1 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 CCF49116.1 - 0.033 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF2118 PF09891.4 CCF49116.1 - 0.056 13.1 0.4 0.26 10.9 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 CCF49116.1 - 0.063 13.6 1.7 1.6 9.0 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_YheCD PF14398.1 CCF49116.1 - 0.11 11.3 0.0 0.19 10.4 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp FHA PF00498.21 CCF49117.1 - 2.5e-08 33.9 0.0 4.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain HIT PF01230.18 CCF49118.1 - 2.3e-24 85.7 0.3 3e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCF49118.1 - 3.5e-14 53.0 0.1 4.8e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCF49118.1 - 1.5e-05 24.5 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Rotamase PF00639.16 CCF49119.1 - 2.7e-23 82.5 0.1 3.8e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCF49119.1 - 1e-19 70.8 0.1 1.3e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CCF49119.1 - 2.5e-07 31.3 0.1 3.8e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CCF49119.1 - 1e-06 28.5 0.7 1e-06 28.5 0.5 1.7 2 0 0 2 2 2 1 WW domain DUF3480 PF11979.3 CCF49120.1 - 0.059 11.9 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) YABBY PF04690.8 CCF49121.1 - 3.4e-09 37.1 0.2 3.5e-09 37.1 0.2 1.0 1 0 0 1 1 1 1 YABBY protein DUF1014 PF06244.7 CCF49121.1 - 1.9e-05 24.8 1.4 2.1e-05 24.7 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 CCF49121.1 - 4.2e-05 23.8 2.4 5.2e-05 23.5 1.7 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CCF49121.1 - 0.00022 21.3 2.6 0.00029 21.0 1.8 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box Pkinase PF00069.20 CCF49122.1 - 3.1e-27 95.3 0.0 5.6e-20 71.5 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49122.1 - 2.4e-07 30.1 0.0 0.00021 20.4 0.0 3.4 3 1 0 3 3 3 1 Protein tyrosine kinase RVT_2 PF07727.9 CCF49123.1 - 2.5e-21 75.7 0.2 1.7e-12 46.8 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF49123.1 - 0.0033 17.0 0.7 0.014 14.9 0.5 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain Tet_JBP PF12851.2 CCF49124.1 - 4e-07 29.4 0.6 8.1e-06 25.2 0.3 2.3 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy PF03171.15 CCF49124.1 - 0.01 16.0 0.1 0.028 14.7 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2360 PF10152.4 CCF49124.1 - 0.046 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MMS1_N PF10433.4 CCF49125.1 - 0.11 10.5 0.0 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 CCF49125.1 - 0.26 11.2 1.3 3.5 7.6 0.0 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_L23eN PF03939.8 CCF49126.1 - 8.1e-19 67.4 10.4 1.9e-18 66.2 7.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 CCF49126.1 - 8.8e-17 60.8 0.8 1.5e-16 60.1 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 AA_permease PF00324.16 CCF49127.1 - 1.6e-118 396.1 44.3 1.9e-118 395.8 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF49127.1 - 1e-33 116.5 45.7 1.3e-33 116.1 31.7 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.16 CCF49127.1 - 0.14 11.8 2.1 8.8 6.0 0.0 3.2 3 0 0 3 3 3 0 Synaptobrevin RhoGEF PF00621.15 CCF49128.1 - 8.1e-40 136.6 2.9 9.4e-40 136.3 1.3 1.7 2 0 0 2 2 2 1 RhoGEF domain SH3_1 PF00018.23 CCF49128.1 - 6.4e-21 73.4 0.8 2.5e-09 36.3 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCF49128.1 - 4.6e-17 61.3 1.7 1.6e-09 37.1 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 CCF49128.1 - 3.4e-16 58.8 0.0 1e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 CCF49128.1 - 8.6e-12 44.3 0.0 2.2e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 CCF49128.1 - 1.2e-08 34.3 0.4 4.4e-08 32.4 0.2 2.1 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 CCF49128.1 - 0.00018 21.5 0.0 0.00048 20.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CCF49128.1 - 0.0027 16.8 0.0 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 EF hand DUF2665 PF11654.3 CCF49129.1 - 1.6e-20 72.3 0.1 2.3e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF2934 PF11154.3 CCF49129.1 - 0.014 14.7 0.4 0.03 13.6 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2934) zf-RING_2 PF13639.1 CCF49130.1 - 3e-11 42.9 9.1 5e-11 42.2 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCF49130.1 - 1.6e-09 37.7 4.3 2.9e-09 36.9 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCF49130.1 - 1.8e-06 27.4 9.0 3e-06 26.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF49130.1 - 2.4e-06 27.4 8.7 3.7e-06 26.8 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF49130.1 - 3.9e-06 26.4 7.2 6.2e-06 25.8 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCF49130.1 - 9.4e-06 25.3 3.5 4.4e-05 23.2 3.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CCF49130.1 - 5.6e-05 22.7 7.6 9.1e-05 22.0 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CCF49130.1 - 0.27 11.2 8.4 0.45 10.5 5.8 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 CCF49130.1 - 0.5 9.9 9.3 0.88 9.2 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 CCF49130.1 - 2.7 8.1 11.0 4.6 7.3 7.6 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 CCF49130.1 - 9.7 5.9 10.1 16 5.2 7.0 1.4 1 0 0 1 1 1 0 PHD-finger PTPlike_phytase PF14566.1 CCF49131.1 - 6.3e-122 402.7 0.2 1e-41 142.4 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 CCF49131.1 - 3e-09 36.5 0.0 0.22 11.1 0.0 4.4 4 0 0 4 4 4 3 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCF49131.1 - 1.8e-06 28.3 0.0 0.75 10.0 0.0 4.2 4 0 0 4 4 4 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCF49131.1 - 0.00016 21.1 0.1 0.16 11.2 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 CCF49131.1 - 0.0013 18.6 0.0 0.47 10.4 0.0 3.3 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha Y_phosphatase2 PF03162.8 CCF49131.1 - 0.24 10.7 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family HisG PF01634.13 CCF49132.1 - 7.7e-46 155.6 0.0 1.3e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CCF49132.1 - 2.8e-25 88.0 0.1 5.6e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 CCF49132.1 - 0.0043 16.6 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.15 CCF49132.1 - 0.084 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Cation_efflux PF01545.16 CCF49133.1 - 1.6e-13 50.4 1.7 2.6e-13 49.7 1.2 1.2 1 0 0 1 1 1 1 Cation efflux family Pkinase PF00069.20 CCF49134.1 - 1.5e-71 240.5 0.0 2e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49134.1 - 6.9e-36 123.6 0.0 9.6e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49134.1 - 2.1e-08 33.4 0.0 3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCF49134.1 - 2.1e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCF49134.1 - 4.8e-05 22.5 0.1 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCF49134.1 - 0.00055 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCF49134.1 - 0.039 13.0 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 CCF49134.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CCF49134.1 - 0.1 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase EssA PF10661.4 CCF49134.1 - 2 8.1 8.8 3.7 7.2 5.1 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA NOA36 PF06524.7 CCF49134.1 - 3.1 6.9 7.1 5.9 6.0 4.9 1.4 1 0 0 1 1 1 0 NOA36 protein DAGK_cat PF00781.19 CCF49135.1 - 1.6e-20 72.8 0.0 4.1e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pox_A_type_inc PF04508.7 CCF49136.1 - 0.19 11.6 1.2 8.5 6.4 0.1 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RibD_C PF01872.12 CCF49137.1 - 1.1e-32 113.2 0.0 1.4e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain HMG_box PF00505.14 CCF49140.1 - 3.1e-11 43.3 5.1 5.6e-10 39.3 3.6 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF49140.1 - 5.6e-05 23.4 2.3 0.00013 22.2 1.6 1.6 1 0 0 1 1 1 1 HMG-box domain ubiquitin PF00240.18 CCF49141.1 - 8.7e-25 85.9 0.3 9.7e-25 85.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCF49141.1 - 6.5e-17 60.9 0.3 7.1e-17 60.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCF49141.1 - 0.00015 21.9 0.1 0.00042 20.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CCF49141.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like tRNA-synt_His PF13393.1 CCF49142.1 - 1.1e-41 142.9 1.3 1.7e-35 122.6 0.0 3.1 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCF49142.1 - 1.3e-17 63.9 0.0 2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF49142.1 - 3.2e-07 30.1 0.0 8.8e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCF49142.1 - 0.00015 20.7 0.6 0.082 11.6 0.1 3.0 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 CCF49142.1 - 0.0026 17.3 3.9 0.017 14.8 2.7 2.5 1 0 0 1 1 1 1 WHEP-TRS domain APG6 PF04111.7 CCF49142.1 - 0.018 14.0 1.1 0.029 13.4 0.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HGTP_anticodon2 PF12745.2 CCF49142.1 - 0.02 14.0 0.5 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Use1 PF09753.4 CCF49143.1 - 1.2e-09 38.0 4.0 3.5e-09 36.4 2.4 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 FlxA PF14282.1 CCF49143.1 - 0.0078 16.1 4.2 0.0078 16.1 2.9 2.3 3 0 0 3 3 3 1 FlxA-like protein zf-HC5HC2H_2 PF13832.1 CCF49144.1 - 1e-32 112.3 6.9 1e-32 112.3 4.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCF49144.1 - 2.8e-24 85.0 4.4 2.8e-24 85.0 3.0 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 CCF49144.1 - 1.9e-21 76.9 1.0 1.9e-21 76.9 0.7 3.9 3 1 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.20 CCF49144.1 - 7.7e-20 70.5 0.6 1.5e-19 69.6 0.4 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 CCF49144.1 - 1.1e-14 53.4 2.6 1.1e-14 53.4 1.8 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 CCF49144.1 - 4.4e-09 36.4 0.1 1.2e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 CCF49144.1 - 9.1e-09 34.8 9.4 9.1e-09 34.8 6.5 2.7 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 CCF49144.1 - 0.49 10.1 14.9 0.048 13.3 1.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Coiled-coil_56 PF09813.4 CCF49145.1 - 2.9e-05 23.9 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Scramblase PF03803.10 CCF49146.1 - 8.8e-60 201.5 0.0 1.2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Scramblase Romo1 PF10247.4 CCF49147.1 - 2e-24 85.5 8.2 2.5e-24 85.2 5.7 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Macro PF01661.16 CCF49148.1 - 2.8e-41 140.1 0.0 4.6e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain Peptidase_M24 PF00557.19 CCF49149.1 - 2.8e-42 144.6 0.2 3.6e-42 144.2 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SDA1 PF05285.7 CCF49149.1 - 0.0014 17.9 12.6 0.002 17.4 8.7 1.1 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.7 CCF49149.1 - 0.0035 15.7 11.6 0.0049 15.2 8.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 CCF49149.1 - 0.015 13.2 8.6 0.023 12.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CCF49149.1 - 0.038 13.5 12.1 0.061 12.9 8.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 CCF49149.1 - 0.061 11.3 9.2 0.084 10.8 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CCF49149.1 - 0.46 8.9 11.2 0.57 8.5 7.8 1.1 1 0 0 1 1 1 0 Daxx Family NST1 PF13945.1 CCF49149.1 - 1.3 9.0 9.2 2.2 8.3 6.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Nucleoplasmin PF03066.10 CCF49149.1 - 2.4 7.6 9.1 5.2 6.5 6.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin HSP90 PF00183.13 CCF49149.1 - 2.6 6.3 11.7 4.2 5.6 8.1 1.2 1 0 0 1 1 1 0 Hsp90 protein SURF2 PF05477.6 CCF49149.1 - 6.1 5.9 13.4 1.8 7.6 7.0 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) GATase_2 PF00310.16 CCF49150.1 - 3.5e-25 88.4 0.0 4.6e-20 71.6 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCF49150.1 - 2.6e-15 56.5 0.0 8.8e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CCF49150.1 - 7.6e-14 51.5 0.3 4.3e-13 49.0 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 CCF49150.1 - 2.5e-12 46.6 0.0 6.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCF49150.1 - 1.2e-07 30.7 0.0 6.8e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Activator_LAG-3 PF11498.3 CCF49150.1 - 0.071 11.8 2.0 0.11 11.2 1.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 cwf18 PF08315.7 CCF49151.1 - 7.3e-26 91.1 4.0 1.1e-25 90.5 2.8 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF4109 PF13397.1 CCF49151.1 - 0.0036 17.6 1.2 0.031 14.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4109) CHASE PF03924.8 CCF49151.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 CHASE domain YL1 PF05764.8 CCF49152.1 - 1.6e-48 165.4 21.7 1.6e-48 165.4 15.1 2.9 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 CCF49152.1 - 5.4e-15 54.6 0.6 9.5e-15 53.8 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.1 CCF49153.1 - 0.00014 21.5 0.0 0.00039 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF49153.1 - 0.0042 17.4 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF49153.1 - 0.0055 17.2 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CCF49153.1 - 0.022 15.2 0.0 1.7 9.2 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCF49153.1 - 0.034 14.6 0.1 2.7 8.4 0.1 2.6 1 1 0 1 1 1 0 Methyltransferase domain zf-RING_6 PF14835.1 CCF49154.1 - 0.17 11.7 0.1 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 CCF49154.1 - 0.25 11.7 2.4 0.54 10.7 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF49154.1 - 2.6 8.5 5.9 4.8 7.7 4.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3808 PF10300.4 CCF49155.1 - 2.6e-71 240.6 1.2 4.6e-71 239.7 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 CCF49155.1 - 6.5e-34 116.7 0.2 1.5e-33 115.5 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCF49155.1 - 6.1e-14 52.1 0.0 1.7e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF49155.1 - 5.4e-11 42.4 0.4 2.5e-10 40.3 0.3 2.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPR_12 PF13424.1 CCF49155.1 - 2.7e-05 24.0 3.8 0.14 12.1 0.8 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCF49155.1 - 0.00091 18.8 10.1 0.069 12.8 1.2 4.9 3 2 1 4 4 4 1 TPR repeat DUF4366 PF14283.1 CCF49155.1 - 0.0023 17.4 6.1 0.0023 17.4 4.2 2.6 2 1 1 3 3 2 2 Domain of unknown function (DUF4366) TPR_2 PF07719.12 CCF49155.1 - 0.0059 16.4 12.5 0.82 9.7 0.7 5.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF49155.1 - 0.11 13.1 2.1 4 8.3 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF49155.1 - 0.48 11.0 5.1 1.1 9.9 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF49155.1 - 3.6 7.6 6.0 2.4 8.1 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat DIOX_N PF14226.1 CCF49156.1 - 8.9e-10 39.1 0.0 3e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCF49156.1 - 2.6e-09 37.2 0.0 6.9e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.16 CCF49157.1 - 8.8e-41 140.1 0.0 1.7e-40 139.2 0.0 1.5 1 1 0 1 1 1 1 Amidase Abhydrolase_5 PF12695.2 CCF49158.1 - 3.6e-21 75.4 0.0 1.2e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF49158.1 - 7.5e-16 58.6 0.1 1.1e-13 51.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF49158.1 - 6.8e-11 42.1 0.0 7.6e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 CCF49158.1 - 1.4e-05 23.7 1.4 0.0052 15.3 0.0 2.9 2 2 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CCF49158.1 - 0.00068 19.1 0.0 0.0087 15.5 0.0 2.5 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 CCF49158.1 - 0.0032 16.7 0.0 0.17 11.1 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 CCF49158.1 - 0.0049 16.5 0.1 0.15 11.7 0.0 2.8 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CCF49158.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CCF49158.1 - 0.014 14.8 0.4 0.051 12.9 0.2 2.0 1 1 0 1 1 1 0 Putative esterase Peptidase_M76 PF09768.4 CCF49159.1 - 2.5e-61 206.1 0.0 3.4e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family Rcd1 PF04078.8 CCF49160.1 - 8.4e-128 424.7 0.7 1.1e-127 424.3 0.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cyto_heme_lyase PF01265.12 CCF49161.1 - 1.1e-71 241.4 9.1 1.9e-70 237.4 6.3 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PMM PF03332.8 CCF49162.1 - 1.6e-99 331.9 2.0 4.3e-99 330.5 1.4 1.6 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CCF49162.1 - 1.8e-05 24.4 0.0 0.00037 20.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Chordopox_A13L PF05961.6 CCF49162.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Mre11_DNA_bind PF04152.9 CCF49163.1 - 5.5e-44 150.1 0.1 5.5e-44 150.1 0.0 2.6 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCF49163.1 - 1.6e-24 86.3 0.3 2.4e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DNA_pol_phi PF04931.8 CCF49163.1 - 1.6 6.3 19.8 2.5 5.7 13.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF619 PF04768.8 CCF49164.1 - 5.2e-34 117.1 0.2 8.3e-22 77.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) RVT_2 PF07727.9 CCF49166.1 - 8.4e-49 165.7 0.1 1.3e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pec_lyase_C PF00544.14 CCF49169.1 - 1.2e-13 50.9 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Pectate lyase PAT1 PF09770.4 CCF49169.1 - 4.8 5.3 31.1 6.1 4.9 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPP4R2 PF09184.6 CCF49169.1 - 5.3 6.5 18.8 9 5.7 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 rve PF00665.21 CCF49172.1 - 6.7e-11 42.3 0.8 3.6e-08 33.5 0.6 2.8 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF49172.1 - 0.016 14.7 0.1 0.058 12.9 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Acetyltransf_9 PF13527.1 CCF49174.1 - 0.02 14.7 0.2 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain OPT PF03169.10 CCF49175.1 - 9.3e-98 328.2 40.5 1.3e-97 327.8 28.1 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3938 PF13074.1 CCF49175.1 - 0.0037 17.0 0.4 0.026 14.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3938) DNase_NucA_NucB PF14040.1 CCF49176.1 - 7.8e-19 67.9 2.1 7.8e-19 67.9 1.4 1.6 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB UBX PF00789.15 CCF49177.1 - 0.00059 19.8 0.1 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 UBX domain DUF2422 PF10337.4 CCF49178.1 - 4.2e-82 276.3 7.0 2.9e-79 267.0 0.0 4.2 3 1 0 4 4 4 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CCF49178.1 - 7e-55 186.1 11.1 5e-54 183.3 0.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 CCF49178.1 - 4.8e-08 32.9 11.5 4.8e-08 32.9 7.9 3.4 2 2 1 3 3 3 1 Fusaric acid resistance protein-like DUF1510 PF07423.6 CCF49178.1 - 0.0046 16.3 0.8 0.0046 16.3 0.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) Otopetrin PF03189.8 CCF49178.1 - 0.27 10.1 3.5 0.77 8.6 2.4 1.7 1 0 0 1 1 1 0 Otopetrin G0-G1_switch_2 PF15103.1 CCF49178.1 - 4.8 7.4 9.8 0.98 9.6 3.6 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Hid1 PF12722.2 CCF49178.1 - 6.2 4.3 23.1 0.013 13.2 4.7 2.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CCF49178.1 - 6.8 6.3 26.9 3.3 7.3 1.2 3.0 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Kei1 PF08552.6 CCF49178.1 - 7.3 6.2 9.0 2.1 7.9 2.1 2.8 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4557 PF15101.1 CCF49178.1 - 9 6.0 24.2 0.15 11.8 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CMAS PF02353.15 CCF49179.1 - 2.1e-37 128.7 2.6 3e-37 128.1 1.8 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 CCF49179.1 - 1.2e-14 54.1 0.0 1.4e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF49179.1 - 1.5e-14 54.0 0.3 3.3e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF49179.1 - 3.9e-13 49.6 0.0 1.1e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF49179.1 - 6.1e-11 42.6 0.0 2.6e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF49179.1 - 1.4e-10 41.7 0.0 5.9e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCF49179.1 - 1.8e-08 33.9 0.0 3.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CCF49179.1 - 3.5e-06 27.3 0.0 1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CCF49179.1 - 7.4e-05 22.0 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 CCF49179.1 - 8.9e-05 21.6 0.0 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 CCF49179.1 - 0.0045 16.2 0.0 0.014 14.6 0.0 1.6 1 1 1 2 2 2 1 O-methyltransferase GidB PF02527.10 CCF49179.1 - 0.01 15.0 0.0 0.054 12.6 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF938 PF06080.7 CCF49179.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 CCF49179.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CCF49179.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FTO_CTD PF12934.2 CCF49179.1 - 0.19 11.3 2.3 0.21 11.1 0.8 1.7 2 0 0 2 2 2 0 FTO C-terminal domain tRNA_int_end_N2 PF12928.2 CCF49180.1 - 8.2e-16 57.2 0.0 1.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term DUF3439 PF11921.3 CCF49180.1 - 0.049 13.3 12.0 0.11 12.2 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CCF49180.1 - 1.5 6.7 15.9 2.4 6.0 11.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PTS_2-RNA PF01885.11 CCF49181.1 - 1.4e-55 187.4 1.9 1.4e-54 184.2 1.3 2.3 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4140 PF13600.1 CCF49181.1 - 2.6 8.5 7.3 1.1 9.8 0.8 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SET PF00856.23 CCF49182.1 - 0.0042 17.3 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 SET domain V-ATPase_C PF03223.10 CCF49183.1 - 2.2e-114 382.2 1.3 2.5e-114 382.0 0.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C RRM_1 PF00076.17 CCF49184.1 - 5.4e-15 54.7 0.0 2.1e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49184.1 - 3.6e-08 33.2 0.0 2.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49184.1 - 2.2e-06 27.4 0.0 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HlyD PF00529.15 CCF49184.1 - 0.62 9.3 9.4 1 8.6 6.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein PLRV_ORF5 PF01690.12 CCF49184.1 - 6.7 5.7 19.1 0.15 11.1 0.3 2.2 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein adh_short PF00106.20 CCF49185.1 - 2e-20 73.3 3.7 4.4e-20 72.2 2.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF49185.1 - 4e-11 42.9 0.5 5.9e-11 42.3 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF49185.1 - 8e-11 42.1 0.2 9.9e-11 41.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CCF49185.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_4 PF07993.7 CCF49185.1 - 0.015 14.2 1.2 0.37 9.6 0.9 2.5 1 1 0 1 1 1 0 Male sterility protein PsbY PF06298.6 CCF49185.1 - 0.17 11.4 2.3 0.4 10.2 1.6 1.7 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Fasciclin PF02469.17 CCF49186.1 - 2.6e-26 92.1 2.0 1.9e-19 69.9 0.1 2.4 2 1 0 2 2 2 2 Fasciclin domain DUF912 PF06024.7 CCF49187.1 - 0.083 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rhomboid PF01694.17 CCF49188.1 - 3.3e-07 30.4 17.4 3.3e-07 30.4 12.1 3.3 2 1 1 3 3 3 1 Rhomboid family RNA_pol_Rpb4 PF03874.11 CCF49189.1 - 1.6e-12 47.4 1.8 9.2e-12 44.9 1.3 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 CCF49190.1 - 7.5e-55 180.9 17.6 1.7e-10 40.3 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CCF49190.1 - 7.1e-11 40.9 12.0 0.059 11.5 0.0 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 eIF2A PF08662.6 CCF49190.1 - 1.3e-08 34.8 2.2 0.00015 21.5 0.1 3.5 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCF49190.1 - 0.042 13.3 0.0 12 5.5 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 CCF49190.1 - 0.066 11.4 0.5 0.67 8.1 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Nbas_N PF15492.1 CCF49190.1 - 0.11 11.5 3.0 1.9 7.5 0.2 3.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 CCF49190.1 - 0.14 11.5 2.3 9.1 5.6 0.2 2.9 1 1 2 3 3 3 0 PQQ-like domain DUF1295 PF06966.7 CCF49191.1 - 3e-35 121.6 3.0 3.4e-34 118.1 2.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCF49191.1 - 1.6 8.9 5.8 0.59 10.3 0.1 3.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Kinesin PF00225.18 CCF49192.1 - 1.5e-106 355.9 0.5 1.5e-106 355.9 0.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain SAICAR_synt PF01259.13 CCF49193.1 - 4.1e-78 261.9 0.0 5.1e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Kinesin PF00225.18 CCF49194.1 - 2.9e-82 276.0 0.0 6.6e-82 274.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Pico_P1A PF02226.11 CCF49197.1 - 0.11 12.2 0.1 12 5.7 0.0 2.1 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) RIO1 PF01163.17 CCF49200.1 - 6.5e-41 139.7 0.1 1.8e-28 99.2 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 CCF49200.1 - 6.6e-33 112.6 0.1 1.4e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CCF49200.1 - 4e-08 33.3 0.8 3.3e-05 23.7 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCF49200.1 - 0.00091 18.3 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.2 CCF49200.1 - 0.0026 17.3 0.0 0.052 13.2 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.1 CCF49200.1 - 0.02 14.7 0.0 0.075 12.8 0.0 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Phage_rep_O PF04492.8 CCF49200.1 - 0.083 13.1 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage replication protein O E1_DerP2_DerF2 PF02221.10 CCF49201.1 - 7.8e-24 84.4 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CCF49201.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 ML-like domain DUF1180 PF06679.7 CCF49201.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4625 PF15418.1 CCF49201.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) DUF4098 PF13345.1 CCF49202.1 - 6.1e-11 42.1 5.2 2.7e-07 30.4 0.2 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF4098) OppC_N PF12911.2 CCF49202.1 - 0.09 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PPR_2 PF13041.1 CCF49203.1 - 2.2e-36 123.5 1.1 8.5e-08 32.0 0.0 8.7 8 1 1 9 9 9 6 PPR repeat family PPR_1 PF12854.2 CCF49203.1 - 5.8e-25 86.4 8.1 3.3e-07 29.6 0.1 9.8 12 0 0 12 12 12 5 PPR repeat PPR PF01535.15 CCF49203.1 - 8e-21 72.5 18.2 1.8e-06 27.5 0.4 11.2 12 0 0 12 12 12 3 PPR repeat PPR_3 PF13812.1 CCF49203.1 - 1e-20 72.1 21.4 0.0044 17.1 0.1 12.4 14 0 0 14 14 14 6 Pentatricopeptide repeat domain TPR_14 PF13428.1 CCF49203.1 - 2.4e-05 24.5 8.3 12 6.8 0.0 7.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCF49203.1 - 0.02 15.2 6.6 2 8.7 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Snf7 PF03357.16 CCF49204.1 - 2.3e-32 111.7 10.4 2.7e-32 111.5 7.2 1.1 1 0 0 1 1 1 1 Snf7 Bac_GDH PF05088.7 CCF49204.1 - 0.5 7.6 6.9 0.57 7.5 4.8 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Peptidase_M24 PF00557.19 CCF49206.1 - 9.1e-48 162.5 0.0 1.5e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCF49206.1 - 3.6e-35 120.2 0.0 7.2e-35 119.2 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain GST_N_3 PF13417.1 CCF49207.1 - 7.9e-11 42.0 0.1 2.4e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF49207.1 - 5.5e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF49207.1 - 1.5e-06 27.9 0.1 4.4e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCF49207.1 - 0.00032 20.8 0.0 0.00066 19.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCF49207.1 - 0.00062 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TipAS PF07739.8 CCF49207.1 - 0.1 12.9 0.4 0.47 10.7 0.1 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain GST_C_3 PF14497.1 CCF49207.1 - 0.12 12.8 0.1 0.39 11.2 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IlvN PF07991.7 CCF49208.1 - 1.2e-44 151.5 0.0 1.9e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 CCF49208.1 - 7.1e-43 146.0 0.0 1.1e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 CCF49208.1 - 0.0021 18.4 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCF49208.1 - 0.038 13.8 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Serglycin PF04360.7 CCF49208.1 - 3.7 7.2 8.3 26 4.5 3.8 2.4 2 0 0 2 2 2 0 Serglycin NAD_binding_8 PF13450.1 CCF49211.1 - 5.9e-09 35.8 0.0 2e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCF49211.1 - 0.00014 22.0 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCF49211.1 - 0.00077 18.6 0.0 0.0099 14.9 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 CCF49211.1 - 0.0022 17.7 0.4 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 CCF49211.1 - 0.004 16.1 0.0 0.01 14.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCF49211.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF521 PF04412.8 CCF49212.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RRS1 PF04939.7 CCF49213.1 - 1e-57 194.1 5.0 1e-57 194.1 3.5 1.7 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) TraG_N PF07916.6 CCF49213.1 - 3.7 5.8 4.7 5.6 5.2 3.2 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2407_C PF13373.1 CCF49213.1 - 7.8 6.4 6.5 4.2 7.3 2.9 1.7 1 1 0 1 1 1 0 DUF2407 C-terminal domain WD40 PF00400.27 CCF49214.1 - 9.5e-45 148.9 16.7 6.1e-11 41.7 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCF49214.1 - 0.0076 14.4 0.8 0.54 8.3 0.5 2.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 MIF4G PF02854.14 CCF49215.1 - 1.4e-23 83.4 0.1 2e-22 79.6 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CCF49215.1 - 1.7e-12 47.0 0.0 3.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 MA3 domain DEAD PF00270.24 CCF49216.1 - 6e-42 142.9 0.0 1.5e-41 141.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF49216.1 - 9.7e-26 89.4 0.1 4.5e-25 87.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCF49216.1 - 1.2e-07 30.8 0.0 2.9e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCF49216.1 - 5.8e-06 26.2 0.2 2.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCF49216.1 - 0.00081 17.9 0.0 0.047 12.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1253) DUF2075 PF09848.4 CCF49216.1 - 0.0074 15.3 0.0 0.016 14.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 CCF49216.1 - 0.0083 15.8 0.1 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Herpes_ori_bp PF02399.10 CCF49216.1 - 0.012 13.5 0.0 0.019 12.9 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_22 PF13401.1 CCF49216.1 - 0.037 14.1 1.1 0.18 11.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.7 CCF49216.1 - 1.3 8.8 5.0 2.4 7.9 3.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.2 CCF49217.1 - 7.1e-10 38.4 1.4 7.1e-10 38.4 1.0 1.9 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 CCF49217.1 - 1.7e-06 27.6 1.5 1.4e-05 24.8 0.9 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat F-box PF00646.28 CCF49217.1 - 1.8e-06 27.4 0.6 1.8e-06 27.4 0.4 2.1 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.20 CCF49218.1 - 6.7e-64 215.5 3.6 2.2e-63 213.8 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49218.1 - 2e-40 138.5 0.0 3.2e-37 128.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF49218.1 - 2.2e-07 30.1 0.0 3.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CCF49218.1 - 0.022 13.5 0.2 0.022 13.5 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CCF49218.1 - 0.051 13.3 0.1 0.17 11.6 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCF49218.1 - 0.052 12.8 0.1 0.052 12.8 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF506 PF04720.7 CCF49218.1 - 0.7 9.4 0.0 0.7 9.4 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF506) Zip PF02535.17 CCF49218.1 - 7.4 5.4 32.2 0.14 11.0 4.3 3.5 3 0 0 3 3 3 0 ZIP Zinc transporter HTH_3 PF01381.17 CCF49219.1 - 1.1e-12 47.5 0.2 2e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 CCF49219.1 - 1.2e-11 44.4 1.6 1.8e-11 43.8 0.5 1.8 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.1 CCF49219.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CCF49219.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Response_reg PF00072.19 CCF49220.1 - 2.9e-19 69.1 0.0 7.4e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CCF49220.1 - 3.9e-17 61.9 0.1 8.9e-17 60.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CCF49220.1 - 1.7e-07 31.1 0.1 5.2e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 CCF49220.1 - 0.066 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 GAF domain zf-ZPR1 PF03367.8 CCF49221.1 - 3.5e-103 341.5 2.4 3.8e-52 175.7 0.0 3.1 3 0 0 3 3 3 3 ZPR1 zinc-finger domain HypA PF01155.14 CCF49221.1 - 0.0023 17.5 1.8 0.66 9.6 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 CCF49221.1 - 0.0075 15.4 6.5 0.87 8.8 0.2 2.8 2 1 0 2 2 2 2 zinc-ribbon domain Skp1_POZ PF03931.10 CCF49221.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain UPF0547 PF10571.4 CCF49221.1 - 0.018 14.7 3.2 0.3 10.8 0.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DZR PF12773.2 CCF49221.1 - 0.076 12.8 8.1 0.86 9.4 0.1 3.2 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CCF49221.1 - 0.17 11.3 11.2 0.13 11.7 0.3 3.5 3 1 1 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCF49221.1 - 0.61 9.7 2.8 18 5.0 0.0 2.9 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 CCF49221.1 - 6.8 7.0 8.6 35 4.7 0.4 3.8 2 2 1 3 3 3 0 Restriction alleviation protein Lar Pro_isomerase PF00160.16 CCF49222.1 - 3.9e-40 137.5 0.0 6.7e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPX PF03105.14 CCF49223.1 - 1.9e-51 175.4 20.7 1.1e-49 169.7 14.3 2.2 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCF49223.1 - 2.8e-30 105.6 36.4 4.2e-30 105.0 25.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCF49223.1 - 1.8e-19 69.5 34.7 1.5e-13 50.1 13.1 2.2 1 1 1 2 2 2 2 Citrate transporter RRN3 PF05327.6 CCF49223.1 - 4.5 5.2 6.1 1.2 7.1 1.8 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 WD40 PF00400.27 CCF49224.1 - 7e-38 127.1 6.9 1e-09 37.9 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCF49224.1 - 1.2e-32 111.6 0.7 3e-32 110.3 0.5 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 CCF49224.1 - 0.0002 20.7 0.0 0.037 13.5 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CCF49224.1 - 0.01 14.6 0.0 0.046 12.4 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.3 CCF49224.1 - 0.07 11.2 2.7 0.78 7.7 0.5 2.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 NAP PF00956.13 CCF49225.1 - 6.2e-41 140.1 0.7 6.2e-41 140.1 0.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HSDR_N_2 PF13588.1 CCF49225.1 - 0.016 14.9 0.2 0.026 14.3 0.1 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) YL1 PF05764.8 CCF49225.1 - 0.042 13.4 5.8 0.055 13.0 4.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 CCF49225.1 - 0.051 13.1 8.7 0.1 12.1 6.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 CCF49225.1 - 4.3 7.5 10.7 12 6.1 7.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nop14 PF04147.7 CCF49225.1 - 7.5 4.3 10.2 8 4.2 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3292 PF11696.3 CCF49226.1 - 0.00023 19.1 5.9 0.0026 15.6 0.7 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3292) Methyltransf_4 PF02390.12 CCF49227.1 - 8.4e-49 165.2 0.0 5.8e-37 126.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CCF49227.1 - 0.0019 18.7 0.0 0.009 16.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF49227.1 - 0.0049 16.8 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF49227.1 - 0.051 14.0 0.0 5.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CCF49227.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCF49227.1 - 0.067 12.5 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 CCF49227.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain NDUFB10 PF10249.4 CCF49228.1 - 0.0054 16.8 0.3 0.0062 16.6 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 CheZ PF04344.8 CCF49228.1 - 0.03 14.0 0.4 0.033 13.8 0.3 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF2616 PF11077.3 CCF49228.1 - 0.12 11.8 0.6 0.15 11.5 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Prefoldin_2 PF01920.15 CCF49229.1 - 3.2e-21 75.0 4.0 3.2e-21 75.0 2.8 1.5 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin PF02996.12 CCF49229.1 - 0.0031 17.1 7.4 0.007 15.9 4.5 2.2 1 1 1 2 2 2 1 Prefoldin subunit TMF_TATA_bd PF12325.3 CCF49229.1 - 0.0086 15.8 5.0 0.012 15.3 3.0 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF812 PF05667.6 CCF49229.1 - 0.018 13.5 8.9 0.032 12.7 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Cortex-I_coil PF09304.5 CCF49229.1 - 0.34 10.9 7.4 3 7.9 0.8 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil HsbA PF12296.3 CCF49229.1 - 0.63 9.9 6.6 0.48 10.2 2.3 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A IncA PF04156.9 CCF49229.1 - 1.9 8.0 9.8 4.6 6.7 6.8 1.6 1 1 0 1 1 1 0 IncA protein NTR2 PF15458.1 CCF49229.1 - 2.1 7.5 10.7 0.15 11.2 1.4 2.3 1 1 0 2 2 2 0 Nineteen complex-related protein 2 BLOC1_2 PF10046.4 CCF49229.1 - 2.3 8.3 6.0 3.7 7.7 0.7 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1451 PF07295.6 CCF49229.1 - 2.5 7.8 6.5 0.78 9.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) APG6 PF04111.7 CCF49229.1 - 5.8 5.8 7.8 13 4.7 5.2 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 SSP160 PF06933.6 CCF49229.1 - 9.9 3.9 7.5 11 3.8 5.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CH PF00307.26 CCF49230.1 - 1.3e-69 231.0 0.0 9.6e-19 67.4 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCF49230.1 - 2e-07 30.5 0.0 0.73 9.5 0.0 4.2 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 CCF49230.1 - 6.9e-06 26.1 0.7 2.7e-05 24.1 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCF49230.1 - 0.00079 18.5 0.7 0.037 13.3 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CCF49230.1 - 0.037 13.8 0.9 15 5.8 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain Abhydrolase_6 PF12697.2 CCF49231.1 - 2.1e-18 67.0 0.0 3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF49231.1 - 3.4e-09 36.6 0.0 6e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF49231.1 - 8.4e-06 25.5 0.2 0.00022 20.8 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCF49231.1 - 0.0051 16.0 0.0 0.39 9.9 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CCF49231.1 - 0.027 13.9 0.0 4.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCF49231.1 - 0.044 13.2 0.3 0.52 9.7 0.2 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) TUDOR PF00567.19 CCF49232.1 - 2.2e-05 24.2 0.0 7.1e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Tudor domain DUF1325 PF07039.6 CCF49232.1 - 0.00015 21.3 0.1 0.00031 20.3 0.1 1.6 1 1 1 2 2 2 1 SGF29 tudor-like domain Exonuc_VII_L PF02601.10 CCF49232.1 - 0.017 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cnd1_N PF12922.2 CCF49232.1 - 0.028 14.0 0.9 0.065 12.8 0.6 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2856 PF11043.3 CCF49232.1 - 0.1 12.7 0.9 0.66 10.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) PAT1 PF09770.4 CCF49232.1 - 2.6 6.1 21.7 3.2 5.8 15.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Na_H_Exchanger PF00999.16 CCF49233.1 - 4.2e-65 219.7 49.0 5.9e-65 219.2 33.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Response_reg PF00072.19 CCF49234.1 - 1.5e-20 73.2 0.0 5.6e-10 39.2 0.0 3.6 3 0 0 3 3 3 3 Response regulator receiver domain HATPase_c PF02518.21 CCF49234.1 - 2.6e-17 62.5 0.2 5.6e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CCF49234.1 - 3.2e-16 59.0 0.0 1e-15 57.4 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 CCF49234.1 - 3.1e-06 27.3 0.1 0.00052 20.1 0.0 3.5 4 0 0 4 4 4 1 GAF domain zf-H2C2_2 PF13465.1 CCF49235.1 - 1.1e-17 63.3 2.9 3.9e-07 30.0 0.1 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCF49235.1 - 2.3e-13 49.4 12.2 8.4e-05 22.6 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CCF49235.1 - 3.1e-12 46.0 16.8 3.6e-05 23.8 0.1 4.2 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCF49235.1 - 1.1e-06 28.6 0.9 0.24 11.6 0.0 3.6 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF49235.1 - 0.0053 16.9 5.4 1.1 9.6 0.0 4.0 3 1 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCF49235.1 - 0.021 14.7 3.4 0.68 9.9 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 CCF49235.1 - 0.064 13.0 3.2 0.44 10.3 0.1 2.8 2 1 1 3 3 3 0 BED zinc finger RRM_1 PF00076.17 CCF49236.1 - 4.4e-18 64.6 0.0 6.8e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49236.1 - 1.1e-14 54.0 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49236.1 - 2.7e-09 36.7 0.0 4.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CCF49236.1 - 2.9e-08 33.9 2.1 3.4e-07 30.4 0.6 2.5 1 1 1 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Proteasome PF00227.21 CCF49237.1 - 5.1e-51 172.6 0.0 6.5e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF49237.1 - 5.7e-12 44.7 0.2 9.4e-12 44.0 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2560 PF10834.3 CCF49237.1 - 0.06 13.3 0.4 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) Cohesin PF00963.13 CCF49237.1 - 0.082 12.7 0.2 0.95 9.3 0.1 2.1 2 0 0 2 2 2 0 Cohesin domain gpD PF02925.11 CCF49237.1 - 0.1 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D DUF2188 PF09954.4 CCF49237.1 - 1.5 8.8 6.5 22 5.0 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) NBP1 PF08537.5 CCF49239.1 - 0.062 12.4 0.1 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 CTP_transf_1 PF01148.15 CCF49241.1 - 6.2e-05 22.7 8.3 6.2e-05 22.7 5.8 3.7 2 2 0 2 2 2 1 Cytidylyltransferase family LSM PF01423.17 CCF49243.1 - 3.7e-17 61.6 0.4 5.4e-17 61.0 0.3 1.3 1 0 0 1 1 1 1 LSM domain DUF3296 PF11726.3 CCF49243.1 - 0.026 14.1 0.0 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) Svf1 PF08622.5 CCF49244.1 - 2.5e-107 358.6 0.1 2.8e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Svf1-like PQQ PF01011.16 CCF49244.1 - 0.1 12.2 0.7 0.77 9.4 0.1 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Aconitase PF00330.15 CCF49245.1 - 4.1e-73 246.4 0.3 5.3e-47 160.3 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCF49245.1 - 2.7e-19 69.5 0.1 1.4e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Aconitase C-terminal domain Cyclin_N PF00134.18 CCF49246.1 - 3.1e-36 123.7 0.1 5.3e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCF49246.1 - 1.7e-09 37.6 1.3 3.7e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DDHD PF02862.12 CCF49246.1 - 4.9 6.8 12.8 3.1 7.5 0.1 2.8 3 0 0 3 3 3 0 DDHD domain FAM196 PF15265.1 CCF49246.1 - 6.9 5.7 13.2 0.21 10.7 4.2 1.8 2 0 0 2 2 2 0 FAM196 family zf-LYAR PF08790.6 CCF49248.1 - 5e-12 45.2 2.0 1e-11 44.3 1.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger RRM_6 PF14259.1 CCF49248.1 - 4.4e-07 29.7 0.0 2.3e-06 27.4 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF49248.1 - 0.00034 20.1 0.0 0.004 16.7 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.4 CCF49248.1 - 2.2 6.8 30.6 0.13 10.8 13.6 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GatB_N PF02934.10 CCF49249.1 - 1.3e-108 362.3 0.0 2e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCF49249.1 - 6.9e-28 97.2 0.8 2.1e-27 95.6 0.6 1.8 1 1 0 1 1 1 1 GatB domain Beta_elim_lyase PF01212.16 CCF49250.1 - 5.7e-67 225.8 0.0 7.8e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pcc1 PF09341.5 CCF49250.1 - 1.8e-15 56.7 0.0 4.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor Pcc1 DegT_DnrJ_EryC1 PF01041.12 CCF49250.1 - 0.0013 17.8 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCF49250.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II PC_rep PF01851.17 CCF49251.1 - 2e-42 141.0 11.3 9.1e-07 28.7 0.0 9.4 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCF49251.1 - 3.1e-17 62.6 4.2 1e-10 41.7 0.0 4.9 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 CCF49251.1 - 2.3e-09 37.4 0.6 0.0013 19.1 0.0 4.7 3 0 0 3 3 3 3 HEAT-like repeat HEAT PF02985.17 CCF49251.1 - 2.2e-07 30.3 0.4 2.3 8.5 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 CCF49251.1 - 0.026 14.9 2.5 37 5.1 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Hus1 PF04005.7 CCF49252.1 - 7.8e-86 287.6 1.2 8.9e-86 287.4 0.8 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.13 CCF49252.1 - 0.0021 17.5 0.2 0.0054 16.2 0.1 1.7 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 CCF49252.1 - 0.07 12.2 0.3 0.3 10.1 0.2 2.1 1 1 0 1 1 1 0 Rad9 VPS28 PF03997.7 CCF49253.1 - 4e-59 199.4 1.2 4.6e-59 199.2 0.8 1.0 1 0 0 1 1 1 1 VPS28 protein UvrD_C PF13361.1 CCF49253.1 - 0.018 14.5 2.9 0.087 12.2 0.1 1.8 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Sod_Ni PF09055.6 CCF49253.1 - 0.065 13.6 0.3 13 6.1 0.0 2.2 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase ubiquitin PF00240.18 CCF49254.1 - 0.00035 19.9 0.0 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CCF49254.1 - 0.0019 18.0 0.0 0.0058 16.4 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BatD PF13584.1 CCF49254.1 - 0.01 14.4 0.1 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF2407 PF10302.4 CCF49254.1 - 0.017 15.2 1.6 0.023 14.8 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain SDH_sah PF01972.11 CCF49254.1 - 4.2 6.0 4.7 4.1 6.1 0.9 2.1 2 0 0 2 2 2 0 Serine dehydrogenase proteinase tRNA-synt_1c PF00749.16 CCF49255.1 - 8.9e-108 359.6 0.0 1.4e-107 359.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCF49255.1 - 4.6e-34 117.5 0.2 9e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CCF49255.1 - 1.2e-06 28.9 1.0 7.8e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF49255.1 - 0.0046 16.9 0.5 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCF49255.1 - 0.033 14.0 0.1 0.092 12.6 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNase_H2-Ydr279 PF09468.5 CCF49255.1 - 1.4 8.0 8.5 3.2 6.8 5.9 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TFIIB PF00382.14 CCF49256.1 - 4e-37 125.8 0.7 2.7e-22 78.3 0.2 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCF49256.1 - 4.6e-13 48.2 1.6 7.4e-13 47.6 1.1 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CCF49256.1 - 0.00034 20.5 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain PG_binding_1 PF01471.13 CCF49256.1 - 0.057 13.4 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Cyclin_N PF00134.18 CCF49256.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Nup84_Nup100 PF04121.8 CCF49257.1 - 3e-107 359.0 0.0 6.2e-54 182.8 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 C2 PF00168.25 CCF49258.1 - 7.4e-17 60.9 0.0 4.2e-12 45.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Ribul_P_3_epim PF00834.14 CCF49259.1 - 1.1e-62 210.6 0.1 1.5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 CCF49259.1 - 0.018 15.0 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.14 CCF49259.1 - 0.022 14.2 0.0 0.056 12.9 0.0 1.7 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 CCF49259.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.7 1 1 0 1 1 1 0 PcrB family Mago-bind PF09282.5 CCF49261.1 - 2e-12 46.4 2.8 4.5e-12 45.2 1.9 1.6 1 0 0 1 1 1 1 Mago binding X PF00739.14 CCF49261.1 - 1.7 8.5 6.1 0.33 10.8 1.3 1.8 1 1 1 2 2 2 0 Trans-activation protein X BORG_CEP PF14957.1 CCF49261.1 - 5.9 7.8 12.4 53 4.7 8.6 2.4 1 1 0 1 1 1 0 Cdc42 effector MAPEG PF01124.13 CCF49262.1 - 8.1e-14 51.3 3.1 8.1e-14 51.3 2.1 1.8 1 1 1 2 2 2 1 MAPEG family GST_N PF02798.15 CCF49263.1 - 7.3e-17 61.3 0.0 1.2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCF49263.1 - 2e-11 43.9 0.0 3.7e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF49263.1 - 9.4e-09 35.1 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF49263.1 - 2.8e-08 33.5 0.1 4.6e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF49263.1 - 6.7e-08 32.4 0.0 9.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF49263.1 - 2.1e-05 24.8 0.1 3.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.3 CCF49263.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) COX5B PF01215.14 CCF49265.1 - 1.4e-37 128.4 0.0 1.6e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 CCF49265.1 - 0.026 14.3 1.6 0.04 13.7 1.1 1.3 1 0 0 1 1 1 0 Zinc-finger domain AMP-binding PF00501.23 CCF49266.1 - 1e-84 284.3 0.0 1.3e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF49266.1 - 7.5e-09 36.4 0.1 2.1e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.1 CCF49266.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 CCF49267.1 - 0.063 13.1 5.3 0.13 12.1 3.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF49269.1 - 7.7e-22 77.3 0.2 3.6e-21 75.2 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF49269.1 - 2.3e-06 27.4 6.0 3.9e-06 26.6 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCLC PF05934.6 CCF49269.1 - 7.3 4.7 5.1 12 4.0 3.5 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Kelch_4 PF13418.1 CCF49270.1 - 1.5e-21 75.9 7.6 1.3e-05 24.8 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CCF49270.1 - 6.3e-12 45.3 20.2 0.00036 20.6 0.2 6.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CCF49270.1 - 3.2e-10 39.7 11.0 0.0028 17.5 0.3 7.0 7 1 0 7 7 7 2 Kelch motif Kelch_6 PF13964.1 CCF49270.1 - 4.5e-07 29.7 10.3 0.029 14.5 0.0 5.2 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CCF49270.1 - 0.00047 19.8 0.1 8.4 6.3 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Gly-zipper_OmpA PF13436.1 CCF49270.1 - 0.046 13.3 3.5 0.14 11.8 2.4 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Pkinase PF00069.20 CCF49271.1 - 3.8e-49 167.1 0.0 5.7e-49 166.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49271.1 - 4.3e-46 157.0 0.0 6.3e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CCF49271.1 - 5.2e-07 29.3 2.0 1.1e-06 28.2 1.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 CCF49271.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C1_3 PF07649.7 CCF49271.1 - 0.055 13.5 1.3 0.15 12.1 0.9 1.7 1 0 0 1 1 1 0 C1-like domain APH PF01636.18 CCF49271.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-HC5HC2H_2 PF13832.1 CCF49271.1 - 0.13 12.2 0.7 0.28 11.1 0.5 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 CCF49271.1 - 0.13 11.9 4.0 0.3 10.7 2.8 1.6 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.11 CCF49271.1 - 0.16 12.1 2.9 0.32 11.1 2.0 1.5 1 0 0 1 1 1 0 C1 domain Ebp2 PF05890.7 CCF49272.1 - 4e-88 295.2 18.9 4e-88 295.2 13.1 2.2 3 1 0 3 3 3 1 Eukaryotic rRNA processing protein EBP2 LEA_5 PF00477.12 CCF49273.1 - 0.0076 16.5 0.7 0.0088 16.3 0.5 1.1 1 0 0 1 1 1 1 Small hydrophilic plant seed protein ABC2_membrane PF01061.19 CCF49274.1 - 1.2e-36 125.9 18.1 1.2e-36 125.9 12.5 1.8 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CCF49274.1 - 1.6e-22 80.2 0.1 3.1e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CCF49274.1 - 1.1e-08 35.3 0.0 1.8e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CCF49274.1 - 0.0015 17.6 23.8 0.0015 17.6 16.5 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 CCF49274.1 - 0.0099 15.0 0.2 0.035 13.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCF49274.1 - 0.011 15.7 0.4 0.025 14.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CCF49274.1 - 0.043 13.9 0.1 0.14 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CCF49274.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF4407 PF14362.1 CCF49275.1 - 3.9 6.3 6.2 4.2 6.2 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.5 CCF49275.1 - 4.1 6.8 14.7 5 6.6 10.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.7 CCF49275.1 - 4.2 7.1 7.1 4.5 7.0 4.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CCF49275.1 - 4.9 6.4 12.5 5.4 6.3 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 CCF49275.1 - 5.6 6.5 14.5 6.7 6.3 10.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med15_fungi PF05397.7 CCF49276.1 - 6.7e-31 106.6 1.8 6.7e-31 106.6 1.2 4.0 5 0 0 5 5 5 1 Mediator complex subunit 15 ARID PF01388.16 CCF49276.1 - 6.1e-18 64.4 0.0 3.6e-17 62.0 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain P3A PF08727.6 CCF49277.1 - 0.0001 21.5 0.1 0.089 12.1 0.0 3.5 3 0 0 3 3 3 2 Poliovirus 3A protein like PhoD PF09423.5 CCF49277.1 - 0.0013 17.3 0.3 0.0027 16.3 0.1 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase DUF1970 PF09301.5 CCF49278.1 - 0.025 14.6 1.0 0.054 13.5 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Mur_ligase PF01225.20 CCF49279.1 - 0.09 12.8 0.6 9.1 6.4 0.0 2.5 1 1 1 2 2 2 0 Mur ligase family, catalytic domain Glyco_hydro_45 PF02015.11 CCF49281.1 - 1.4e-48 165.6 6.4 2e-48 165.1 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 C2 PF00168.25 CCF49282.1 - 2.1e-49 165.3 0.4 8.1e-13 48.0 0.0 4.5 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 CCF49282.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DUF2753 PF10952.3 CCF49282.1 - 0.17 11.8 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2753) Ubiq_cyt_C_chap PF03981.7 CCF49283.1 - 3.8e-29 101.3 2.3 4.1e-27 94.7 0.0 3.1 3 0 0 3 3 3 2 Ubiquinol-cytochrome C chaperone PP2C PF00481.16 CCF49284.1 - 3.7e-36 124.8 0.0 8.5e-33 113.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C WAC_Acf1_DNA_bd PF10537.4 CCF49285.1 - 3.9e-38 129.7 0.1 3.9e-38 129.7 0.1 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCF49285.1 - 1.2e-14 53.7 0.0 2.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CCF49285.1 - 2.4e-05 24.0 0.2 6.4e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 DBP10CT PF08147.7 CCF49285.1 - 0.0054 16.5 2.6 0.015 15.1 1.8 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain DUF2985 PF11204.3 CCF49286.1 - 6.1e-32 109.2 2.9 1.1e-31 108.4 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) 5-FTHF_cyc-lig PF01812.15 CCF49286.1 - 0.081 12.6 0.0 0.081 12.6 0.0 2.6 4 0 0 4 4 4 0 5-formyltetrahydrofolate cyclo-ligase family Molybdopterin PF00384.17 CCF49287.1 - 8.5e-76 255.4 0.0 3.8e-75 253.2 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 CCF49287.1 - 4.6e-18 64.1 1.3 6.5e-18 63.6 0.0 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 CCF49287.1 - 4.6e-17 61.5 0.1 1.2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1982 PF09326.6 CCF49287.1 - 8.9e-17 60.9 0.1 2.6e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 CCF49287.1 - 2.2e-08 33.7 0.5 2.2e-08 33.7 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 CCF49287.1 - 0.0016 18.2 0.1 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4_6 PF12837.2 CCF49287.1 - 0.28 11.1 2.4 0.39 10.6 0.6 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 CCF49287.1 - 0.32 11.4 3.1 0.82 10.1 2.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Aha1_N PF09229.6 CCF49288.1 - 3.5e-33 114.3 0.0 4.9e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCF49288.1 - 1.6e-16 60.5 0.0 1e-15 57.9 0.0 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 CCF49288.1 - 0.0049 17.0 0.0 0.029 14.5 0.0 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Nefa_Nip30_N PF10187.4 CCF49289.1 - 9.4e-23 80.3 9.3 9.4e-23 80.3 6.4 2.5 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TAF4 PF05236.9 CCF49289.1 - 0.045 13.0 16.4 0.061 12.5 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Spore_coat_CotO PF14153.1 CCF49289.1 - 1.4 8.3 11.7 1.8 7.9 8.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF2201_N PF13203.1 CCF49289.1 - 6.7 5.7 8.4 8.2 5.4 5.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Arm PF00514.18 CCF49290.1 - 8.3e-99 320.4 6.0 8.2e-14 50.8 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCF49290.1 - 7.7e-26 90.1 0.1 1.4e-07 31.6 0.0 6.3 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 CCF49290.1 - 2.3e-23 82.0 0.2 2.4e-08 34.2 0.0 6.0 4 2 1 5 5 5 3 HEAT-like repeat IBB PF01749.15 CCF49290.1 - 2.5e-20 72.4 9.4 4e-20 71.7 6.5 1.3 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 CCF49290.1 - 7.7e-20 69.1 1.1 1.7e-05 24.4 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 CCF49290.1 - 2e-07 29.7 0.0 4.6e-05 21.9 0.0 2.9 1 1 1 2 2 2 1 Adaptin N terminal region Arm_2 PF04826.8 CCF49290.1 - 1.2e-06 27.7 0.0 0.029 13.4 0.0 3.8 2 1 2 4 4 4 2 Armadillo-like RICTOR_V PF14668.1 CCF49290.1 - 0.00016 21.5 2.8 0.088 12.7 0.0 4.2 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 CCF49290.1 - 0.00032 20.8 0.2 1.1 9.8 0.1 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 CCF49290.1 - 0.00043 20.1 0.0 0.24 11.3 0.0 4.3 2 1 1 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 CCF49290.1 - 0.0026 16.1 0.0 1.9 6.6 0.0 2.8 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Mo25 PF08569.6 CCF49290.1 - 0.0078 15.2 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Mo25-like DUF330 PF03886.8 CCF49290.1 - 0.02 14.3 0.1 0.11 11.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF330) U79_P34 PF03064.11 CCF49290.1 - 7 6.0 9.0 9.9 5.5 6.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GTP_cyclohydro2 PF00925.15 CCF49291.1 - 6.6e-65 217.4 0.0 4.1e-59 198.5 0.0 2.3 2 0 0 2 2 2 2 GTP cyclohydrolase II Metallophos PF00149.23 CCF49292.1 - 3.2e-41 140.9 0.2 4.2e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Band_7 PF01145.20 CCF49293.1 - 5.4e-28 98.1 0.8 8.7e-28 97.4 0.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CCF49293.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Ribosomal_L7Ae PF01248.21 CCF49294.1 - 1.9e-23 81.7 0.0 2.2e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FKBP_C PF00254.23 CCF49294.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L37e PF01907.14 CCF49295.1 - 1.7e-25 88.5 10.9 1.7e-25 88.5 7.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCF49295.1 - 0.0032 17.2 1.1 0.0047 16.7 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCF49295.1 - 0.036 13.7 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 SelR domain DUF1462 PF07315.6 CCF49295.1 - 0.072 13.0 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-ribbon_3 PF13248.1 CCF49295.1 - 0.49 9.6 3.5 2.7 7.3 2.6 2.0 1 1 1 2 2 2 0 zinc-ribbon domain DnaJ_CXXCXGXG PF00684.14 CCF49295.1 - 0.68 10.0 5.0 0.41 10.7 2.0 1.6 2 0 0 2 2 2 0 DnaJ central domain Ribosomal_L40e PF01020.12 CCF49295.1 - 3.5 7.2 8.7 1.6 8.4 0.6 2.6 1 1 1 2 2 2 0 Ribosomal L40e family Leo1 PF04004.8 CCF49296.1 - 1.2e-53 181.3 0.2 4.2e-53 179.5 0.2 2.1 1 0 0 1 1 1 1 Leo1-like protein Glypican PF01153.14 CCF49296.1 - 1.4 7.4 5.5 2.5 6.6 3.8 1.5 1 0 0 1 1 1 0 Glypican Mgm101p PF06420.7 CCF49297.1 - 6.9e-84 279.3 0.0 9e-84 279.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Acyl-CoA_dh_1 PF00441.19 CCF49299.1 - 9.2e-44 149.1 0.5 1.4e-43 148.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCF49299.1 - 4.4e-36 123.8 0.0 8e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCF49299.1 - 1.1e-20 74.2 0.1 1.7e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF49299.1 - 3.3e-20 71.3 0.1 7.3e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCF49299.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Tachystatin_B PF11478.3 CCF49299.1 - 0.21 11.3 3.2 0.44 10.3 2.2 1.4 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Yae1_N PF09811.4 CCF49300.1 - 2.8e-11 42.7 7.5 5.3e-11 41.8 5.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 CCF49301.1 - 2.2e-12 46.4 0.5 1.8e-08 33.9 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49301.1 - 1.6e-05 24.7 0.4 0.00036 20.4 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49301.1 - 8.2e-05 22.3 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 CCF49301.1 - 4.6 6.8 10.4 5.7 6.5 0.9 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SAC3_GANP PF03399.11 CCF49303.1 - 3e-35 121.6 0.1 4e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCF49303.1 - 2.4e-29 101.9 0.0 1.2e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 NAM PF02365.10 CCF49303.1 - 0.07 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 No apical meristem (NAM) protein NUDIX PF00293.23 CCF49304.1 - 6.4e-26 90.5 0.0 1.1e-25 89.8 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain RbcS PF12338.3 CCF49304.1 - 8.1 6.3 6.4 13 5.6 4.4 1.3 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit Ribosomal_L6 PF00347.18 CCF49305.1 - 1.7e-23 82.8 0.1 8.6e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 PC-Esterase PF13839.1 CCF49306.1 - 0.015 15.1 0.0 0.049 13.4 0.0 1.7 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MFS_1 PF07690.11 CCF49308.1 - 5.8e-09 35.1 22.8 8.7e-09 34.5 15.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCF49308.1 - 5.5e-07 29.2 2.8 5.5e-07 29.2 1.9 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Aminotran_1_2 PF00155.16 CCF49309.1 - 2e-52 178.3 0.0 3.6e-52 177.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF49309.1 - 0.00014 21.1 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CCF49309.1 - 0.032 12.5 0.0 0.049 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme tRNA-synt_2c PF01411.14 CCF49309.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) zf-DHHC PF01529.15 CCF49310.1 - 7.3e-32 110.1 0.1 1.8e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF2124 PF09897.4 CCF49310.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Formyl_trans_N PF00551.14 CCF49311.1 - 2e-18 66.5 0.0 3.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CCF49311.1 - 0.00094 19.2 0.1 0.0026 17.8 0.1 1.8 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain Acyltransferase PF01553.16 CCF49312.1 - 2.8e-13 49.4 0.0 8e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase AIG2 PF06094.7 CCF49312.1 - 1.1e-12 48.2 0.1 3.4e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family Aminotran_5 PF00266.14 CCF49313.1 - 6.7e-09 34.9 0.0 1.7e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V YqzH PF14164.1 CCF49313.1 - 0.0086 15.9 0.0 0.04 13.8 0.0 2.2 1 0 0 1 1 1 1 YqzH-like protein GCIP PF13324.1 CCF49313.1 - 0.082 12.1 0.1 0.082 12.1 0.1 2.7 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting DUF3337 PF11816.3 CCF49314.1 - 0.0033 16.8 2.3 0.0045 16.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Hex_IIIa PF02455.11 CCF49314.1 - 0.0053 15.4 3.2 0.0071 15.0 2.2 1.1 1 0 0 1 1 1 1 Hexon-associated protein (IIIa) CDC45 PF02724.9 CCF49314.1 - 1.3 6.9 7.7 1.7 6.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2b PF00587.20 CCF49315.1 - 2.2e-44 151.0 0.0 4e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF49315.1 - 9.2e-20 70.3 0.4 2e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CCF49315.1 - 1.5e-11 43.9 0.0 7.6e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 CCF49315.1 - 3.4e-10 39.6 0.0 6.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain SPX PF03105.14 CCF49316.1 - 0.072 12.8 0.0 0.086 12.6 0.0 1.1 1 0 0 1 1 1 0 SPX domain DUF724 PF05266.9 CCF49316.1 - 0.08 12.5 2.4 0.11 12.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PTPA PF03095.10 CCF49317.1 - 5.6e-96 321.2 0.0 8e-96 320.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein AhpC-TSA PF00578.16 CCF49319.1 - 1.2e-23 83.0 0.0 1.8e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCF49319.1 - 1.1e-12 47.6 0.0 2.7e-12 46.4 0.0 1.5 2 0 0 2 2 2 1 Redoxin AhpC-TSA_2 PF13911.1 CCF49319.1 - 0.066 13.1 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Pap_E4 PF02711.9 CCF49319.1 - 0.11 13.2 2.5 0.23 12.2 1.7 1.5 1 0 0 1 1 1 0 E4 protein p450 PF00067.17 CCF49323.1 - 1.4e-69 234.8 0.0 1.8e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 CCF49324.1 - 6.9e-53 179.4 0.0 9.3e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49324.1 - 2.1e-42 144.9 0.0 3.3e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49324.1 - 0.001 18.0 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF49324.1 - 0.015 15.0 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCF49324.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2305 PF10230.4 CCF49325.1 - 2.3e-44 151.8 0.0 1.1e-43 149.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CCF49325.1 - 3.3e-11 43.5 0.3 4.5e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF49325.1 - 4.3e-05 23.3 0.0 7.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chromo PF00385.19 CCF49326.1 - 1e-11 44.2 0.2 2.2e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CCF49326.1 - 2.1e-07 30.6 0.1 0.026 14.3 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain WD40 PF00400.27 CCF49327.1 - 2.4e-65 214.2 13.7 1.7e-09 37.1 0.7 8.8 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 CCF49327.1 - 2.5e-10 39.9 0.0 4.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF49327.1 - 7.4e-10 38.2 0.1 1.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CCF49327.1 - 1.1e-09 36.9 9.5 0.011 13.8 0.0 6.1 2 2 2 5 5 5 4 Nucleoporin Nup120/160 Otopetrin PF03189.8 CCF49327.1 - 1.4 7.8 5.5 2.1 7.2 3.8 1.1 1 0 0 1 1 1 0 Otopetrin CDK5_activator PF03261.10 CCF49327.1 - 6.5 5.9 19.5 4.3 6.5 11.3 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein KOW PF00467.24 CCF49328.1 - 2e-07 30.4 0.8 4.1e-07 29.4 0.5 1.6 1 0 0 1 1 1 1 KOW motif Methyltrans_RNA PF04452.9 CCF49328.1 - 0.068 12.2 0.2 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase Kei1 PF08552.6 CCF49329.1 - 2.4e-53 180.6 3.8 3e-53 180.2 2.6 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Arif-1 PF06770.6 CCF49329.1 - 1.2 8.5 3.5 16 4.8 1.2 2.1 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) DUF4199 PF13858.1 CCF49329.1 - 1.3 8.8 9.5 2.8 7.8 6.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Exo_endo_phos PF03372.18 CCF49331.1 - 0.003 17.5 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 CCF49331.1 - 0.0056 16.0 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Gly-zipper_OmpA PF13436.1 CCF49332.1 - 0.0098 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Per1 PF04080.8 CCF49333.1 - 5.2e-106 353.9 0.3 6.9e-106 353.5 0.2 1.2 1 0 0 1 1 1 1 Per1-like Methyltrn_RNA_3 PF02598.12 CCF49334.1 - 3.7e-81 272.6 0.0 4.7e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase PHA_synth_III_E PF09712.5 CCF49334.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Menin PF05053.8 CCF49334.1 - 8.1 4.4 10.2 13 3.8 7.1 1.3 1 0 0 1 1 1 0 Menin RRM_1 PF00076.17 CCF49335.1 - 4.1e-10 39.1 0.1 1.6e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49335.1 - 8.2e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49335.1 - 2.8e-06 27.0 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) D123 PF07065.9 CCF49336.1 - 4.7e-69 232.7 0.0 6.8e-67 225.6 0.0 2.2 1 1 0 1 1 1 1 D123 HLH PF00010.21 CCF49337.1 - 0.00026 20.6 0.1 0.00059 19.4 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CCF49338.1 - 1.4e-61 207.8 0.0 1.9e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49338.1 - 4.1e-35 121.1 0.0 6.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49338.1 - 2.9e-09 36.3 0.0 5.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF49338.1 - 0.003 17.3 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCF49338.1 - 0.05 12.6 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCF49338.1 - 0.061 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 CCF49338.1 - 0.25 10.1 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Snf7 PF03357.16 CCF49339.1 - 2.5e-42 144.1 20.6 1.2e-41 141.9 14.3 1.8 2 0 0 2 2 2 1 Snf7 Ribosomal_L10 PF00466.15 CCF49339.1 - 0.036 13.9 3.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L10 Ist1 PF03398.9 CCF49339.1 - 0.05 13.0 4.5 0.065 12.6 3.1 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway V_ATPase_I PF01496.14 CCF49339.1 - 0.28 9.0 4.3 0.33 8.7 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1043 PF06295.7 CCF49339.1 - 0.42 10.2 5.6 0.66 9.6 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) PspA_IM30 PF04012.7 CCF49339.1 - 0.49 9.7 22.0 0.015 14.6 4.9 2.1 1 1 0 2 2 2 0 PspA/IM30 family Prefoldin PF02996.12 CCF49339.1 - 0.72 9.5 5.8 0.28 10.8 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 CCF49339.1 - 0.73 9.5 12.4 1.6 8.4 8.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KxDL PF10241.4 CCF49339.1 - 0.91 9.4 8.0 3.2 7.7 0.2 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein COG2 PF06148.6 CCF49339.1 - 1.9 8.3 10.3 0.25 11.2 3.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pox_A_type_inc PF04508.7 CCF49339.1 - 3.3 7.7 8.8 0.64 9.9 3.3 2.1 2 0 0 2 2 1 0 Viral A-type inclusion protein repeat YlqD PF11068.3 CCF49339.1 - 4.5 7.3 17.8 12 5.8 9.5 2.2 1 1 1 2 2 2 0 YlqD protein DUF3435 PF11917.3 CCF49339.1 - 8.4 4.9 16.0 1.5e+02 0.8 11.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4618 PF15397.1 CCF49339.1 - 9.1 5.5 16.5 3.1 7.0 3.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) CLN3 PF02487.12 CCF49340.1 - 3.7e-60 203.8 15.6 6.2e-51 173.4 4.5 4.8 2 1 1 3 3 3 3 CLN3 protein Clp1 PF06807.9 CCF49341.1 - 3.3e-05 23.7 0.0 0.0065 16.2 0.0 2.6 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCF49341.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B W2 PF02020.13 CCF49342.1 - 8.3e-18 64.1 1.4 2.8e-17 62.4 1.0 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CCF49342.1 - 1.8e-10 39.8 9.6 2.9e-05 23.3 2.9 4.2 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CCF49342.1 - 1.4e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCF49342.1 - 0.0003 20.8 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CCF49342.1 - 0.14 10.6 0.3 0.26 9.7 0.2 1.4 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.1 CCF49342.1 - 8 6.1 10.5 21 4.7 5.2 3.1 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase RNA_pol_Rpc4 PF05132.9 CCF49343.1 - 3.2e-28 98.3 0.4 3.2e-28 98.3 0.3 3.6 3 1 0 3 3 3 2 RNA polymerase III RPC4 PGK PF00162.14 CCF49344.1 - 2.5e-148 493.7 0.6 2.9e-148 493.5 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Arginosuc_synth PF00764.14 CCF49345.1 - 6.7e-159 529.0 0.0 7.8e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 CCF49345.1 - 0.00027 20.3 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 CCF49345.1 - 0.0034 16.9 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 CCF49345.1 - 0.021 13.4 0.0 0.057 11.9 0.0 1.7 1 1 1 2 2 2 0 tRNA methyl transferase Iso_dh PF00180.15 CCF49347.1 - 2.7e-91 306.0 0.0 3.5e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.21 CCF49348.1 - 9.5e-10 38.2 8.3 4e-05 23.7 0.3 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF49348.1 - 4.1e-09 36.2 2.4 1.9e-06 27.8 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCF49348.1 - 5.6e-08 32.5 6.5 0.00041 20.4 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-BED PF02892.10 CCF49348.1 - 0.0015 18.2 0.5 0.84 9.4 0.0 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 CCF49348.1 - 0.0047 17.0 10.6 0.12 12.5 0.7 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF49348.1 - 0.093 12.9 5.0 0.68 10.2 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCF49348.1 - 0.096 12.6 3.1 5.8 6.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.10 CCF49348.1 - 0.18 11.2 0.0 5.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 CCF49348.1 - 0.28 11.2 1.3 3.4 7.8 0.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AAA_5 PF07728.9 CCF49349.1 - 7.2e-121 398.3 0.0 3.1e-20 72.3 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 CCF49349.1 - 8.4e-26 90.7 0.0 0.0033 17.6 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 CCF49349.1 - 3.9e-24 84.7 0.0 5.1e-06 26.1 0.0 7.9 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF49349.1 - 2e-23 82.9 3.6 0.0048 17.0 0.0 8.6 7 1 0 7 7 6 5 AAA domain AAA_17 PF13207.1 CCF49349.1 - 8.3e-23 81.5 0.0 0.11 13.2 0.0 7.5 6 0 0 6 6 6 6 AAA domain AAA_33 PF13671.1 CCF49349.1 - 1.4e-20 73.6 1.3 0.097 12.5 0.0 8.0 6 1 0 6 6 6 6 AAA domain AAA_18 PF13238.1 CCF49349.1 - 8.1e-19 68.2 0.1 0.19 12.0 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_19 PF13245.1 CCF49349.1 - 1.6e-16 59.8 9.2 0.008 15.9 0.2 7.3 6 0 0 6 6 6 4 Part of AAA domain ABC_tran PF00005.22 CCF49349.1 - 4.4e-16 59.4 3.9 0.015 15.5 0.0 7.5 8 0 0 8 8 6 3 ABC transporter AAA_28 PF13521.1 CCF49349.1 - 4.8e-15 55.9 0.4 0.034 14.1 0.0 7.2 7 0 0 7 7 6 4 AAA domain AAA_14 PF13173.1 CCF49349.1 - 6.2e-15 55.2 0.0 0.00017 21.5 0.0 7.2 8 0 0 8 8 6 2 AAA domain Sigma54_activ_2 PF14532.1 CCF49349.1 - 6.9e-15 55.2 5.2 0.0049 16.9 0.1 8.0 7 0 0 7 7 7 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 CCF49349.1 - 5.2e-14 51.8 0.9 0.14 11.2 0.0 7.0 6 0 0 6 6 6 3 Zeta toxin Sigma54_activat PF00158.21 CCF49349.1 - 4.9e-13 48.8 0.0 0.063 12.7 0.0 6.1 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_29 PF13555.1 CCF49349.1 - 8.8e-13 47.5 0.9 0.71 9.4 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain UPF0079 PF02367.12 CCF49349.1 - 2.9e-12 46.2 1.8 0.13 11.9 0.0 6.7 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CCF49349.1 - 2.3e-11 43.1 1.2 0.12 11.2 0.0 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_16 PF13191.1 CCF49349.1 - 3.8e-11 43.3 65.3 0.00029 20.8 2.3 12.1 13 1 0 13 13 8 5 AAA ATPase domain Mg_chelatase PF01078.16 CCF49349.1 - 2.7e-10 39.7 3.8 0.25 10.5 0.1 7.6 7 0 0 7 7 7 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCF49349.1 - 4.3e-10 39.3 2.1 0.27 10.6 0.1 6.4 6 0 0 6 6 6 3 AAA domain MobB PF03205.9 CCF49349.1 - 8.1e-10 38.5 0.1 1.8 8.2 0.0 6.0 6 0 0 6 6 5 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCF49349.1 - 9e-10 38.6 0.2 2.4 8.3 0.0 6.6 6 0 0 6 6 6 1 RNA helicase NACHT PF05729.7 CCF49349.1 - 2.6e-09 36.9 2.9 0.1 12.2 0.0 6.8 6 0 0 6 6 5 1 NACHT domain DUF258 PF03193.11 CCF49349.1 - 4.2e-08 32.5 2.1 0.26 10.4 0.0 5.7 6 0 0 6 6 5 1 Protein of unknown function, DUF258 Miro PF08477.8 CCF49349.1 - 7.4e-08 32.9 0.2 29 5.2 0.0 6.7 6 0 0 6 6 6 0 Miro-like protein cobW PF02492.14 CCF49349.1 - 3.8e-06 26.4 2.9 5.1 6.4 0.1 6.2 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCF49349.1 - 4.3e-06 26.2 0.5 2.9 7.3 0.0 5.1 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 CCF49349.1 - 1.5e-05 24.5 1.0 1.6 8.1 0.1 4.6 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_21 PF13304.1 CCF49349.1 - 2.6e-05 24.3 0.0 0.044 13.7 0.0 4.5 5 0 0 5 5 5 1 AAA domain MMR_HSR1 PF01926.18 CCF49349.1 - 6.2e-05 22.9 0.1 1.8 8.5 0.0 5.7 6 0 0 6 6 5 1 50S ribosome-binding GTPase Rad17 PF03215.10 CCF49349.1 - 0.00019 20.2 0.4 3.8 6.0 0.0 4.5 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CCF49349.1 - 0.00043 19.1 1.7 0.026 13.2 0.1 4.0 5 0 0 5 5 5 1 TIP49 C-terminus vWA-TerF-like PF10138.4 CCF49349.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus IPT PF01745.11 CCF49349.1 - 0.0022 17.2 0.2 2.4 7.2 0.0 3.8 4 0 0 4 4 4 1 Isopentenyl transferase NTPase_1 PF03266.10 CCF49349.1 - 0.0024 17.6 2.5 3.6 7.2 0.0 4.7 5 0 0 5 5 4 0 NTPase Arch_ATPase PF01637.13 CCF49349.1 - 0.0024 17.6 0.0 5.4 6.6 0.0 4.9 5 0 0 5 5 5 0 Archaeal ATPase PRK PF00485.13 CCF49349.1 - 0.0043 16.6 0.1 16 4.9 0.0 4.3 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 CCF49349.1 - 0.013 15.0 5.0 33 3.9 0.0 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 CCF49349.1 - 0.021 14.0 0.2 0.88 8.7 0.0 3.8 5 0 0 5 5 3 0 Chromatin associated protein KTI12 Dynamin_N PF00350.18 CCF49349.1 - 0.066 13.0 5.2 5.3 6.8 0.0 5.3 6 0 0 6 6 4 0 Dynamin family AAA_6 PF12774.2 CCF49349.1 - 0.12 11.9 0.0 1.4e+02 1.8 0.0 4.7 6 0 0 6 6 4 0 Hydrolytic ATP binding site of dynein motor region D1 Viral_helicase1 PF01443.13 CCF49349.1 - 0.16 11.4 1.5 31 3.9 0.0 4.3 5 0 0 5 5 3 0 Viral (Superfamily 1) RNA helicase Gtr1_RagA PF04670.7 CCF49349.1 - 0.34 10.0 2.8 13 4.8 0.0 3.7 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region CbiA PF01656.18 CCF49349.1 - 0.36 10.1 2.9 16 4.8 0.1 4.2 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.2 CCF49349.1 - 0.41 9.6 0.0 66 2.4 0.0 3.9 6 0 0 6 6 4 0 P-loop containing dynein motor region D3 KaiC PF06745.8 CCF49349.1 - 1 8.4 0.4 66 2.4 0.0 3.6 4 0 0 4 4 4 0 KaiC PPV_E1_C PF00519.12 CCF49349.1 - 7.2 5.1 0.0 30 3.0 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase TFIIS_C PF01096.13 CCF49350.1 - 1.9e-16 59.3 5.8 3.3e-16 58.6 0.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCF49350.1 - 6e-08 32.2 6.4 8.3e-05 22.1 0.2 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.2 CCF49350.1 - 3.9e-05 23.3 6.7 0.026 14.3 0.1 3.0 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CCF49350.1 - 8.8e-05 21.7 8.7 0.016 14.4 0.4 2.7 2 1 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 CCF49350.1 - 0.00076 18.6 15.9 0.1 11.8 2.1 3.9 3 1 1 4 4 4 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCF49350.1 - 0.001 18.6 5.1 0.063 12.9 0.1 2.7 2 1 0 2 2 2 1 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 CCF49350.1 - 0.002 18.3 9.5 0.0043 17.3 0.5 3.0 2 1 0 2 2 2 1 Restriction alleviation protein Lar Terminase_GpA PF05876.7 CCF49350.1 - 0.0088 14.4 0.3 0.019 13.3 0.2 1.6 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) zf-NADH-PPase PF09297.6 CCF49350.1 - 0.01 15.3 9.4 3 7.4 0.0 4.1 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-ISL3 PF14690.1 CCF49350.1 - 0.01 15.8 7.6 12 6.0 0.0 3.9 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 IBR PF01485.16 CCF49350.1 - 0.011 15.5 3.3 2.1 8.2 0.0 2.6 2 1 0 2 2 2 0 IBR domain zf-LSD1 PF06943.7 CCF49350.1 - 0.012 15.2 0.9 0.012 15.2 0.6 2.1 2 0 0 2 2 1 0 LSD1 zinc finger zf-TFIIB PF13453.1 CCF49350.1 - 0.026 13.6 1.3 0.026 13.6 0.9 2.6 2 2 0 2 2 2 0 Transcription factor zinc-finger Prok-RING_1 PF14446.1 CCF49350.1 - 0.039 13.6 8.8 0.5 10.1 0.5 3.4 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 DUF2387 PF09526.5 CCF49350.1 - 0.046 13.6 3.8 1.9 8.4 0.2 2.7 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-H2C2_2 PF13465.1 CCF49350.1 - 0.047 13.9 0.2 0.047 13.9 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double domain Zn_ribbon_recom PF13408.1 CCF49350.1 - 0.05 13.8 6.7 5 7.4 0.1 3.6 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain HypA PF01155.14 CCF49350.1 - 0.051 13.2 3.2 4.8 6.8 0.0 2.8 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF164 PF02591.10 CCF49350.1 - 0.065 13.0 6.5 2.3 8.1 0.0 3.5 3 1 0 3 3 3 0 Putative zinc ribbon domain CpXC PF14353.1 CCF49350.1 - 0.083 12.8 5.2 6.7 6.6 0.1 3.7 3 1 1 4 4 4 0 CpXC protein zinc_ribbon_5 PF13719.1 CCF49350.1 - 0.11 12.1 11.9 6.5 6.4 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCF49350.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.5 3 1 1 4 4 3 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 CCF49350.1 - 0.13 11.5 0.2 0.13 11.5 0.2 1.9 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 CCF49350.1 - 0.13 12.0 9.3 3.4 7.5 1.5 3.5 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CCF49350.1 - 0.2 11.6 16.0 7.9 6.5 0.6 4.1 2 2 1 4 4 4 0 Zinc ribbon domain Nop10p PF04135.7 CCF49350.1 - 0.21 11.3 2.4 1.7 8.4 0.0 3.2 4 0 0 4 4 3 0 Nucleolar RNA-binding protein, Nop10p family zinc_ribbon_4 PF13717.1 CCF49350.1 - 0.25 11.0 12.6 8.4 6.1 0.4 4.1 3 1 1 4 4 4 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CCF49350.1 - 0.29 10.5 0.2 0.29 10.5 0.1 2.0 2 1 0 2 2 1 0 Baculoviridae late expression factor 5 C-terminal domain DNA_ligase_ZBD PF03119.11 CCF49350.1 - 0.33 10.6 0.2 0.33 10.6 0.2 3.2 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain PolC_DP2 PF03833.8 CCF49350.1 - 0.34 8.5 1.7 0.74 7.4 0.3 1.8 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 zinc-ribbons_6 PF07191.7 CCF49350.1 - 0.64 9.8 5.4 8.6 6.2 0.1 2.9 2 1 0 3 3 3 0 zinc-ribbons zf-MYND PF01753.13 CCF49350.1 - 0.77 9.6 4.2 8.7 6.3 0.2 2.7 2 1 0 2 2 2 0 MYND finger zf-RING_3 PF14369.1 CCF49350.1 - 0.78 9.7 7.3 19 5.3 0.0 3.7 4 0 0 4 4 4 0 zinc-finger Nudix_N_2 PF14803.1 CCF49350.1 - 1.1 8.9 11.2 3.9 7.2 2.2 3.7 3 1 0 3 3 3 0 Nudix N-terminal zf-LITAF-like PF10601.4 CCF49350.1 - 1.2 9.0 5.2 37 4.2 0.0 3.6 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain DNA_RNApol_7kD PF03604.8 CCF49350.1 - 1.3 8.5 12.3 0.5 9.8 1.0 3.4 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit DUF35_N PF12172.3 CCF49350.1 - 1.3 9.0 8.7 13 5.8 0.0 3.9 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PhnA_Zn_Ribbon PF08274.7 CCF49350.1 - 1.6 8.5 10.3 5.5 6.8 0.1 3.3 3 1 0 3 3 2 0 PhnA Zinc-Ribbon UPF0547 PF10571.4 CCF49350.1 - 1.6 8.4 19.6 0.49 10.1 0.2 3.8 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 CCF49350.1 - 1.7 8.5 10.0 6.4 6.6 0.0 3.5 3 1 1 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like zf-C4_Topoisom PF01396.14 CCF49350.1 - 1.7 8.2 14.3 8.2 6.0 1.3 3.5 2 1 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger A2L_zn_ribbon PF08792.5 CCF49350.1 - 1.9 8.0 11.5 3.1 7.3 0.1 3.9 4 0 0 4 4 4 0 A2L zinc ribbon domain Ribosomal_S27e PF01667.12 CCF49350.1 - 2 8.0 7.3 3.2 7.3 0.0 3.5 3 1 1 4 4 4 0 Ribosomal protein S27 Cys_rich_CPCC PF14206.1 CCF49350.1 - 2.1 7.9 5.4 20 4.8 0.2 3.1 3 0 0 3 3 3 0 Cysteine-rich CPCC zf-C2H2 PF00096.21 CCF49350.1 - 3.4 8.2 10.8 1 9.8 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Zn_Tnp_IS1 PF03811.8 CCF49350.1 - 3.7 7.1 5.9 19 4.8 0.0 3.4 4 0 0 4 4 3 0 InsA N-terminal domain zf-tcix PF14952.1 CCF49350.1 - 4.6 6.6 12.3 22 4.5 0.2 4.0 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding DUF3797 PF12677.2 CCF49350.1 - 5 6.8 13.5 4.3 7.0 1.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) DUF1451 PF07295.6 CCF49350.1 - 6.1 6.6 5.8 5.1 6.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1451) Rubredoxin PF00301.15 CCF49350.1 - 6.5 6.7 10.4 16 5.4 0.2 3.9 4 0 0 4 4 4 0 Rubredoxin Ogr_Delta PF04606.7 CCF49350.1 - 9.6 5.9 10.4 27 4.5 0.1 3.3 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger ThiF PF00899.16 CCF49351.1 - 6.8e-32 110.1 0.0 1.2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCF49351.1 - 0.00058 19.9 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase mRNA_cap_enzyme PF01331.14 CCF49352.1 - 5.8e-44 150.0 0.0 7.5e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CCF49352.1 - 4e-14 52.7 0.0 1.4e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CCF49352.1 - 0.00055 19.3 0.1 0.01 15.2 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain CYSTM PF12734.2 CCF49353.1 - 2.1e-07 30.8 21.5 2.1e-07 30.8 14.9 4.3 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 CCF49353.1 - 2.1 8.3 4.4 3.3 7.7 3.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.4 CCF49353.1 - 3.2 7.7 5.8 3.9 7.4 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Proteasome PF00227.21 CCF49354.1 - 1.2e-51 174.6 0.2 1.5e-51 174.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Cellulase PF00150.13 CCF49355.1 - 1.3e-10 40.9 6.1 4.1e-10 39.3 4.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SIR2 PF02146.12 CCF49356.1 - 2.5e-36 125.0 0.0 6.7e-33 113.9 0.0 3.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CCF49356.1 - 0.00098 18.8 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Alpha-L-AF_C PF06964.7 CCF49358.1 - 1.1e-29 103.4 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus RabGAP-TBC PF00566.13 CCF49359.1 - 1.1e-49 168.7 0.8 1.6e-49 168.3 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PPR_1 PF12854.2 CCF49360.1 - 2.4e-13 49.3 1.1 7.5e-06 25.3 0.0 3.5 3 0 0 3 3 3 3 PPR repeat PPR_2 PF13041.1 CCF49360.1 - 4.9e-09 36.0 0.0 0.004 17.1 0.0 3.8 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 CCF49360.1 - 8.7e-09 34.7 0.0 0.011 15.6 0.0 4.2 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 CCF49360.1 - 1.8e-05 24.6 2.2 0.42 11.0 0.0 5.6 6 0 0 6 6 6 2 Pentatricopeptide repeat domain ABC2_membrane PF01061.19 CCF49361.1 - 1.2e-78 263.1 59.0 1.1e-42 145.5 16.3 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCF49361.1 - 1.6e-37 128.8 0.0 6.6e-19 68.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCF49361.1 - 5e-24 83.9 8.4 4.6e-20 71.1 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CCF49361.1 - 5.6e-07 28.9 55.5 7.9e-06 25.1 8.5 4.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_17 PF13207.1 CCF49361.1 - 1.5e-06 29.0 0.3 0.019 15.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 CCF49361.1 - 1.6e-06 28.0 0.6 0.086 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CCF49361.1 - 9.4e-06 25.1 0.2 0.019 14.3 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF49361.1 - 1.1e-05 24.8 0.3 0.0091 15.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF49361.1 - 3.3e-05 24.0 0.1 0.49 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 CCF49361.1 - 4.9e-05 22.8 0.2 0.0079 15.6 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 CCF49361.1 - 6.1e-05 23.0 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 CCF49361.1 - 0.00015 21.2 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 CCF49361.1 - 0.00018 20.7 0.1 0.0049 16.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCF49361.1 - 0.00019 21.5 0.0 0.051 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF49361.1 - 0.0012 18.8 1.2 0.36 10.8 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCF49361.1 - 0.0012 19.1 0.4 0.62 10.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CCF49361.1 - 0.0016 18.6 0.2 0.31 11.2 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_10 PF12846.2 CCF49361.1 - 0.0023 17.4 0.1 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain SMC_N PF02463.14 CCF49361.1 - 0.0036 16.5 0.0 0.044 13.0 0.0 2.5 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 CCF49361.1 - 0.0037 17.2 0.1 0.094 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCF49361.1 - 0.004 16.8 0.3 3.2 7.3 0.1 2.5 2 0 0 2 2 2 2 NACHT domain UPF0079 PF02367.12 CCF49361.1 - 0.0094 15.5 0.4 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CCF49361.1 - 0.024 14.3 0.2 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 CCF49361.1 - 0.047 13.9 0.1 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CCF49361.1 - 0.055 13.4 0.1 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 CCF49361.1 - 0.068 13.6 0.2 12 6.4 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 CCF49361.1 - 0.085 12.4 0.3 6.9 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CCF49361.1 - 0.09 12.6 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CCF49361.1 - 0.12 11.1 0.6 6.7 5.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 CCF49361.1 - 0.14 11.2 1.0 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 CCF49361.1 - 0.16 10.9 0.5 12 4.7 0.0 2.9 3 0 0 3 3 3 0 Septin NB-ARC PF00931.17 CCF49361.1 - 0.31 9.8 0.5 9.7 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Complex1_LYR_1 PF13232.1 CCF49362.1 - 5.2e-08 32.9 3.4 5.2e-08 32.9 2.3 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCF49362.1 - 1.3e-07 31.2 5.9 1.3e-07 31.2 4.1 2.2 1 1 1 2 2 2 1 Complex 1 protein (LYR family) IL34 PF15036.1 CCF49362.1 - 0.097 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin 34 WD40 PF00400.27 CCF49363.1 - 0.026 14.3 0.5 2 8.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat His_Phos_1 PF00300.17 CCF49364.1 - 3.3e-13 50.0 0.0 9.9e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Tex_N PF09371.5 CCF49364.1 - 0.028 13.7 0.4 0.05 12.9 0.3 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF3552 PF12072.3 CCF49364.1 - 0.053 12.7 5.0 0.097 11.8 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Glutaredoxin2_C PF04399.8 CCF49364.1 - 0.098 12.2 0.6 0.21 11.2 0.4 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Palm_thioest PF02089.10 CCF49365.1 - 1.1e-55 188.5 0.0 1.6e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 CCF49365.1 - 4.6e-05 23.4 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF49365.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_2 PF01674.13 CCF49365.1 - 0.051 12.8 0.0 0.64 9.2 0.0 2.2 1 1 0 1 1 1 0 Lipase (class 2) DCAF15_WD40 PF14939.1 CCF49365.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Clat_adaptor_s PF01217.15 CCF49366.1 - 3.7e-17 62.3 0.0 4.5e-14 52.3 0.0 2.2 1 1 1 2 2 2 2 Clathrin adaptor complex small chain Pkinase PF00069.20 CCF49367.1 - 8e-74 248.0 0.0 1.1e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49367.1 - 9.4e-42 142.8 0.0 1.3e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49367.1 - 1.8e-12 46.8 0.0 3.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCF49367.1 - 0.0015 17.6 0.1 0.0051 15.8 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 CCF49368.1 - 1.2e-22 80.1 0.0 3e-14 52.5 0.0 2.4 2 1 0 2 2 2 2 Aldo/keto reductase family Chitin_synth_1 PF01644.12 CCF49369.1 - 5.4e-65 218.1 0.0 8.3e-65 217.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CCF49369.1 - 7e-27 94.0 0.1 1.7e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 CCF49369.1 - 6.4e-26 89.8 0.0 1.2e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 CCF49369.1 - 3.3e-15 56.3 6.3 9.3e-13 48.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF49369.1 - 2.1e-08 34.2 0.0 4.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RabGAP-TBC PF00566.13 CCF49370.1 - 3.7e-20 72.3 1.1 3.8e-16 59.2 0.6 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MFS_1 PF07690.11 CCF49372.1 - 4.7e-25 88.0 34.2 6.3e-25 87.6 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CCF49372.1 - 0.0008 19.1 2.2 0.0019 17.9 0.3 2.6 2 0 0 2 2 2 1 MFS_1 like family DUF1228 PF06779.9 CCF49372.1 - 0.19 11.7 7.2 0.041 13.9 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) NifU_N PF01592.11 CCF49374.1 - 2.8e-52 175.9 0.1 5.4e-52 175.0 0.1 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain Ribosomal_L11 PF00298.14 CCF49375.1 - 4.6e-27 93.9 2.3 7.4e-27 93.2 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CCF49375.1 - 3.8e-23 80.6 0.5 3.8e-23 80.6 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain NUC153 PF08159.7 CCF49376.1 - 4.1e-12 45.4 0.4 8.4e-12 44.4 0.2 1.6 1 0 0 1 1 1 1 NUC153 domain Ribosomal_S16 PF00886.14 CCF49376.1 - 0.048 13.3 0.0 2 8.1 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S16 Proteasome PF00227.21 CCF49377.1 - 6.6e-58 195.1 0.0 1.7e-57 193.7 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF49377.1 - 2.8e-10 39.3 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RabGAP-TBC PF00566.13 CCF49378.1 - 2.2e-12 46.9 0.2 5.3e-12 45.6 0.1 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ras PF00071.17 CCF49379.1 - 1.8e-46 157.4 0.5 2.1e-46 157.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF49379.1 - 5.1e-15 56.0 0.1 8e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF49379.1 - 1.3e-07 31.0 0.0 1.6e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF49379.1 - 8.6e-07 28.9 0.0 1.2e-06 28.4 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF49379.1 - 7.2e-05 22.2 0.4 0.00061 19.2 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCF49379.1 - 0.00015 21.0 0.1 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCF49379.1 - 0.0024 17.1 0.1 0.056 12.7 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 CCF49379.1 - 0.021 14.5 0.1 0.029 14.0 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 CCF49379.1 - 0.092 12.4 0.1 0.23 11.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rpr2 PF04032.11 CCF49380.1 - 1.2e-12 47.4 0.5 1.2e-12 47.4 0.3 2.1 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Suf PF05843.9 CCF49381.1 - 0.4 10.3 3.0 0.75 9.4 2.1 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CCF49381.1 - 3.3 7.2 6.5 5.9 6.4 4.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Glyco_hydro_32N PF00251.15 CCF49382.1 - 8.3e-15 54.9 0.0 4.5e-06 26.2 0.0 2.7 2 1 1 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CCF49382.1 - 5.1e-06 26.7 0.1 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal SKN1 PF03935.10 CCF49383.1 - 5.1e-192 638.4 1.1 6e-192 638.2 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CCF49383.1 - 3.7e-09 36.1 3.7 0.0025 17.1 0.0 3.8 3 1 0 3 3 3 2 Glycosyl hydrolases family 16 Rot1 PF10681.4 CCF49384.1 - 4.2e-60 202.7 1.1 5.3e-60 202.4 0.8 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal adh_short PF00106.20 CCF49386.1 - 2.1e-28 99.3 1.2 3.3e-28 98.6 0.8 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF49386.1 - 1.4e-27 97.0 0.0 1.8e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF49386.1 - 7.5e-17 61.5 0.9 1.4e-16 60.6 0.3 1.6 1 1 0 2 2 2 1 KR domain Epimerase PF01370.16 CCF49386.1 - 6.8e-05 22.4 0.1 9.1e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCF49386.1 - 0.00019 21.4 0.1 0.0018 18.3 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 CCF49386.1 - 0.0014 19.0 0.3 3.4 8.1 0.0 2.9 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent SBP_bac_5 PF00496.17 CCF49386.1 - 0.0033 16.2 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle 3HCDH_N PF02737.13 CCF49386.1 - 0.0074 15.9 0.2 1.4 8.5 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCF49386.1 - 0.064 12.2 0.1 0.81 8.5 0.0 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NmrA PF05368.8 CCF49386.1 - 0.07 12.3 0.4 0.12 11.6 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_2 PF03446.10 CCF49386.1 - 0.089 12.6 0.5 0.75 9.6 0.1 2.4 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase RCC1 PF00415.13 CCF49387.1 - 9.8e-22 76.9 2.8 0.004 17.3 0.0 8.3 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCF49387.1 - 4.7e-10 38.8 21.2 0.034 13.7 0.0 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Actin PF00022.14 CCF49388.1 - 2.7e-114 381.6 0.0 4.2e-114 381.0 0.0 1.3 1 1 0 1 1 1 1 Actin BOP1NT PF08145.7 CCF49389.1 - 4.7e-106 354.2 5.2 7.2e-106 353.6 3.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CCF49389.1 - 7e-24 82.7 14.2 1.1e-06 28.2 0.2 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat DUF2838 PF10998.3 CCF49390.1 - 6.1e-41 138.7 10.0 1.4e-40 137.6 6.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) G-gamma PF00631.17 CCF49390.1 - 0.53 10.0 7.2 0.15 11.8 1.0 2.7 3 0 0 3 3 3 0 GGL domain DNA_RNApol_7kD PF03604.8 CCF49391.1 - 5.6e-17 60.9 5.9 7.1e-17 60.5 4.1 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf-ISL3 PF14690.1 CCF49391.1 - 0.014 15.4 0.8 0.014 15.4 0.5 1.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 CCF49391.1 - 0.014 15.1 0.6 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 CCF49391.1 - 0.018 14.7 0.2 0.021 14.5 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GFA PF04828.9 CCF49391.1 - 0.033 14.1 0.7 2.6 8.0 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 CCF49391.1 - 0.034 14.0 2.9 0.093 12.6 2.0 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Herpes_UL49_1 PF03117.9 CCF49391.1 - 0.046 12.8 0.1 0.047 12.7 0.1 1.0 1 0 0 1 1 1 0 UL49 family NinF PF05810.7 CCF49391.1 - 0.093 12.5 0.3 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 NinF protein Zn_ribbon_recom PF13408.1 CCF49391.1 - 0.2 11.9 3.2 0.32 11.2 0.8 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain TFIIS_C PF01096.13 CCF49391.1 - 0.23 11.1 1.6 3.2 7.4 0.2 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF2197 PF09963.4 CCF49391.1 - 0.36 10.8 5.6 4.3 7.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF2296 PF10058.4 CCF49391.1 - 0.56 10.0 2.7 2.2 8.1 0.1 2.0 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 CCF49391.1 - 0.82 9.5 4.2 1.3 8.8 0.7 1.8 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Adap_comp_sub PF00928.16 CCF49392.1 - 2e-45 154.9 0.0 3.8e-45 154.0 0.0 1.5 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCF49392.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RNase_H2_suC PF08615.6 CCF49392.1 - 0.045 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nucleoplasmin PF03066.10 CCF49392.1 - 0.066 12.7 3.8 0.056 12.9 1.6 1.5 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CCF49392.1 - 0.22 11.7 6.7 0.47 10.7 4.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2890 PF11081.3 CCF49392.1 - 0.31 11.0 6.2 0.54 10.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SH3_1 PF00018.23 CCF49393.1 - 2.5e-22 77.9 0.0 1.8e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CCF49393.1 - 2e-14 52.7 0.0 4e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 CCF49393.1 - 4.5e-14 51.7 0.0 8.3e-07 28.5 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 CCF49393.1 - 3.6e-09 36.4 0.0 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 PX domain PB1 PF00564.19 CCF49393.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 PB1 domain RRM_1 PF00076.17 CCF49394.1 - 1.5e-26 91.8 0.0 1.2e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49394.1 - 3.6e-20 71.7 0.0 1.2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49394.1 - 9.7e-10 38.1 0.0 4.2e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF49394.1 - 2.2e-05 24.0 0.3 0.015 15.0 0.0 2.7 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 CCF49394.1 - 0.00077 19.2 0.0 0.19 11.5 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Peptidase_C13 PF01650.13 CCF49395.1 - 3.1e-40 138.1 0.0 4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF4447 PF14590.1 CCF49395.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) DUF3439 PF11921.3 CCF49395.1 - 5.4 6.7 12.4 13 5.5 8.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) GYF PF02213.11 CCF49396.1 - 2.9 7.5 5.5 1.3e+02 2.2 0.0 4.1 5 0 0 5 5 5 0 GYF domain DUF3818 PF12825.2 CCF49398.1 - 3e-78 262.8 0.0 4e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCF49398.1 - 5.8e-05 22.7 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 PX-associated Glyco_hydro_cc PF11790.3 CCF49400.1 - 3e-52 177.4 10.2 4.1e-52 176.9 7.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 CCF49400.1 - 0.00044 19.1 0.1 0.001 17.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DUF1510 PF07423.6 CCF49400.1 - 0.0017 17.7 1.2 0.003 16.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SAPS PF04499.10 CCF49400.1 - 0.0019 16.9 1.1 0.0025 16.5 0.8 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 CCF49400.1 - 0.012 14.1 5.7 0.014 13.9 3.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 CCF49400.1 - 0.085 12.7 6.9 0.047 13.5 3.3 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2413 PF10310.4 CCF49400.1 - 0.57 8.9 10.1 0.76 8.5 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) EVI2A PF05399.6 CCF49400.1 - 1.9 7.6 16.7 11 5.1 9.5 2.3 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) DUF2217 PF10265.4 CCF49400.1 - 3.8 6.1 16.1 6.1 5.4 11.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CCF49400.1 - 8.1 4.3 20.3 12 3.8 14.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CCF49400.1 - 9.2 4.4 24.9 13 3.8 17.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DAO PF01266.19 CCF49401.1 - 1.6e-19 70.0 0.1 1.1e-11 44.2 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCF49401.1 - 0.0007 19.9 0.0 0.0027 18.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF49401.1 - 0.00078 19.3 0.0 0.0097 15.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF49401.1 - 0.0018 18.2 0.1 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCF49401.1 - 0.0021 16.9 0.0 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCF49401.1 - 0.01 14.9 0.5 0.022 13.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 CCF49401.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CCF49401.1 - 0.024 14.8 0.0 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 CCF49401.1 - 0.076 13.0 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 CCF49401.1 - 0.15 11.6 0.0 0.47 10.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2OG-FeII_Oxy PF03171.15 CCF49402.1 - 7e-23 80.8 0.0 1.1e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CCF49402.1 - 3.6e-18 66.1 0.0 6.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2029 PF09594.5 CCF49404.1 - 0.17 11.3 5.7 0.037 13.5 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) SKG6 PF08693.5 CCF49404.1 - 0.24 10.7 3.2 0.9 8.9 2.2 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF262 PF03235.9 CCF49405.1 - 5.5e-15 55.9 0.0 1.2e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF262 DUF1748 PF08520.5 CCF49406.1 - 1.4e-28 98.3 0.0 1.6e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Pkinase PF00069.20 CCF49407.1 - 1.2e-68 231.0 0.0 1.9e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49407.1 - 4.8e-30 104.4 0.2 1.3e-28 99.8 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49407.1 - 1.7e-10 40.3 0.4 0.0012 17.9 0.0 3.1 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.9 CCF49407.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCF49407.1 - 0.19 11.4 0.0 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sedlin_N PF04628.8 CCF49408.1 - 8e-32 109.8 0.0 1.9e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCF49408.1 - 4.2e-05 23.2 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Sybindin-like family bZIP_1 PF00170.16 CCF49409.1 - 7.3e-10 38.6 6.3 1.2e-09 37.9 4.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCF49409.1 - 2.4e-05 24.0 7.4 4.7e-05 23.1 5.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCF49409.1 - 0.019 15.2 9.3 0.036 14.3 6.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2353 PF09789.4 CCF49409.1 - 0.031 13.5 3.3 0.041 13.1 2.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) FlaC_arch PF05377.6 CCF49409.1 - 0.044 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_S49_N PF08496.5 CCF49409.1 - 0.24 11.1 1.1 0.32 10.7 0.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Macoilin PF09726.4 CCF49409.1 - 1.7 6.7 10.6 8.2 4.5 7.3 1.8 1 1 0 1 1 1 0 Transmembrane protein GTP_EFTU PF00009.22 CCF49410.1 - 1.1e-45 155.4 0.0 1.9e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCF49410.1 - 2.2e-26 91.9 0.2 8.5e-26 90.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCF49410.1 - 2.7e-09 36.9 0.7 7.1e-09 35.6 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF49410.1 - 0.00016 21.5 0.0 0.0004 20.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CCF49410.1 - 0.018 14.6 0.4 0.05 13.2 0.2 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PAM2 PF07145.10 CCF49410.1 - 0.29 10.7 7.7 1 8.9 0.1 3.4 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DAD PF02109.11 CCF49411.1 - 7.4e-48 161.3 1.0 8.7e-48 161.0 0.7 1.0 1 0 0 1 1 1 1 DAD family Rho_GDI PF02115.12 CCF49412.1 - 1.6e-60 203.9 0.0 1.7e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF3744 PF12558.3 CCF49412.1 - 0.043 14.2 0.2 11 6.6 0.0 2.9 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter E1_DerP2_DerF2 PF02221.10 CCF49412.1 - 0.084 13.1 0.1 0.51 10.5 0.0 2.0 1 1 0 1 1 1 0 ML domain TauD PF02668.11 CCF49413.1 - 7e-58 196.3 0.2 1.3e-57 195.4 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UbiA PF01040.13 CCF49413.1 - 3e-26 92.1 24.1 3e-26 92.1 16.7 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF1640 PF07798.6 CCF49413.1 - 1.2e-16 61.2 1.5 2.3e-16 60.3 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Cu_amine_oxidN1 PF07833.6 CCF49413.1 - 0.054 13.8 1.5 0.074 13.3 0.0 2.0 2 0 0 2 2 2 0 Copper amine oxidase N-terminal domain Fzo_mitofusin PF04799.8 CCF49413.1 - 0.37 10.1 2.2 0.68 9.2 1.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region Pyr_redox_2 PF07992.9 CCF49417.1 - 3.1e-10 40.2 0.0 1.2e-09 38.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF49417.1 - 2.9e-09 37.2 0.0 0.01 15.9 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF49417.1 - 7.9e-09 35.8 0.1 0.00063 20.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF49417.1 - 3.3e-06 26.2 0.4 0.045 12.6 0.1 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCF49417.1 - 1.7e-05 23.9 0.0 7.4e-05 21.8 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CCF49417.1 - 0.0025 18.0 0.0 0.33 11.2 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 CCF49417.1 - 0.0028 16.3 1.2 7.2 5.1 0.1 3.1 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_9 PF13454.1 CCF49417.1 - 0.0055 16.4 1.7 1.9 8.2 0.0 3.7 3 1 0 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.13 CCF49417.1 - 0.11 12.5 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Serpulina_VSP PF05540.6 CCF49417.1 - 0.21 10.3 0.0 0.37 9.5 0.0 1.3 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein Lycopene_cycl PF05834.7 CCF49417.1 - 1.5 7.6 3.1 50 2.6 0.0 3.3 3 1 1 4 4 4 0 Lycopene cyclase protein SRPRB PF09439.5 CCF49418.1 - 2.4e-12 46.4 0.0 7e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCF49418.1 - 6.2e-06 25.7 0.1 0.00021 20.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCF49418.1 - 1.4e-05 25.5 0.1 8.3e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 CCF49418.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CCF49418.1 - 4e-05 22.9 0.0 7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 CCF49418.1 - 0.033 13.3 0.2 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCF49418.1 - 0.051 12.8 0.0 0.41 9.9 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 CCF49418.1 - 0.13 11.9 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Proteasome PF00227.21 CCF49419.1 - 1.4e-46 158.1 0.0 1.8e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF49419.1 - 1.9e-13 49.4 0.0 4.3e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF883 PF05957.8 CCF49420.1 - 4.5e-05 23.7 33.7 0.053 13.9 4.7 3.6 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CCF49420.1 - 0.00068 19.1 6.7 0.00068 19.1 4.7 1.8 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.8 CCF49420.1 - 0.05 12.9 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 fzo-like conserved region DBINO PF13892.1 CCF49420.1 - 1.1 9.2 21.6 1.2 9.1 4.8 2.3 1 1 1 2 2 2 0 DNA-binding domain SART-1 PF03343.8 CCF49421.1 - 1.3e-139 466.3 53.0 1.7e-139 465.9 36.7 1.1 1 0 0 1 1 1 1 SART-1 family PQ-loop PF04193.9 CCF49422.1 - 9.8e-35 117.9 4.4 3.8e-18 64.7 1.2 2.5 2 0 0 2 2 2 2 PQ loop repeat Form-deh_trans PF09163.6 CCF49422.1 - 0.0075 15.7 0.0 0.024 14.0 0.0 1.8 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane UPF0113 PF03657.8 CCF49423.1 - 1.7e-08 34.2 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Utp14 PF04615.8 CCF49424.1 - 1.5e-162 542.4 40.2 1.5e-162 542.4 27.9 2.5 1 1 1 2 2 2 1 Utp14 protein RhoGAP PF00620.22 CCF49425.1 - 8.9e-26 90.3 0.0 1.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M23 PF01551.17 CCF49426.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M23 DUF1523 PF07509.6 CCF49426.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Y_phosphatase PF00102.22 CCF49427.1 - 2.6e-36 125.1 0.0 7.3e-36 123.6 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCF49427.1 - 5.5e-05 22.7 0.0 0.00015 21.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DSBA PF01323.15 CCF49428.1 - 6e-26 91.1 0.0 6.9e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain HpcH_HpaI PF03328.9 CCF49429.1 - 5.4e-39 133.3 0.0 8e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CCF49429.1 - 3.4e-11 42.5 0.0 1.5e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_1_2 PF00155.16 CCF49430.1 - 1.8e-44 152.2 0.0 2.6e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PQ-loop PF04193.9 CCF49431.1 - 2.4e-20 71.8 9.5 6.3e-15 54.4 0.4 2.8 3 0 0 3 3 3 2 PQ loop repeat Endonuclease_NS PF01223.18 CCF49432.1 - 2.7e-50 170.9 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease E1_dh PF00676.15 CCF49433.1 - 4.4e-88 294.8 0.0 5.3e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CCF49433.1 - 2.9e-06 26.3 0.0 4.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CCF49433.1 - 0.0053 15.7 0.0 0.021 13.7 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.3 CCF49433.1 - 0.099 12.2 0.5 0.25 10.9 0.3 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Glyco_hydro_61 PF03443.9 CCF49434.1 - 0.16 11.7 3.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Aminotran_3 PF00202.16 CCF49436.1 - 1.7e-78 263.8 0.0 2.4e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCF49436.1 - 0.039 12.9 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II GFO_IDH_MocA PF01408.17 CCF49437.1 - 5.5e-21 75.2 0.1 8.6e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pex19 PF04614.7 CCF49438.1 - 5.4e-66 222.7 3.6 5.4e-66 222.7 2.5 1.8 1 1 1 2 2 2 1 Pex19 protein family Pup PF05639.6 CCF49438.1 - 0.028 14.9 3.3 0.11 13.0 0.2 2.8 2 0 0 2 2 2 0 Pup-like protein DUF2884 PF11101.3 CCF49438.1 - 0.11 11.8 0.4 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) RasGAP_C PF03836.10 CCF49439.1 - 1.5e-43 147.8 6.3 4.6e-43 146.3 4.4 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 CCF49439.1 - 9.1e-42 142.9 0.6 2.1e-41 141.7 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 CCF49439.1 - 1e-22 77.5 42.3 0.062 12.9 0.0 11.9 11 0 0 11 11 11 9 IQ calmodulin-binding motif CH PF00307.26 CCF49439.1 - 9.6e-12 44.9 0.0 3.5e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain PAZ_siRNAbind PF12212.3 CCF49439.1 - 0.053 13.1 0.7 9.8 5.8 0.2 2.7 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain p450 PF00067.17 CCF49442.1 - 1e-71 241.8 0.0 9e-71 238.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.7 CCF49442.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 SUR7/PalI family Endosulfine PF04667.12 CCF49443.1 - 3.9e-20 71.6 0.6 5.9e-20 71.0 0.4 1.3 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Porin_3 PF01459.17 CCF49444.1 - 2e-67 227.4 0.3 2.2e-67 227.2 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zn_clus PF00172.13 CCF49446.1 - 0.00017 21.4 8.5 0.00032 20.5 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 CCF49446.1 - 0.017 15.4 0.0 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS PF00989.19 CCF49446.1 - 0.028 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 PAS fold DUF663 PF04950.7 CCF49447.1 - 6.7e-85 284.6 0.0 6.7e-85 284.6 0.0 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCF49447.1 - 1.2e-28 98.4 0.0 2.9e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCF49447.1 - 3.1e-06 26.7 0.0 0.00031 20.2 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CCF49447.1 - 3e-05 23.7 0.1 8.6e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCF49447.1 - 6.4e-05 23.0 0.1 0.00029 20.8 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 CCF49447.1 - 8.2e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCF49447.1 - 0.0006 20.2 1.6 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 CCF49447.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCF49447.1 - 0.0019 17.7 0.1 0.0072 15.8 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCF49447.1 - 0.0023 18.7 0.0 0.0023 18.7 0.0 3.9 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.22 CCF49447.1 - 0.0061 16.8 1.8 0.017 15.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 CCF49447.1 - 0.0064 16.4 0.3 0.027 14.4 0.2 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCF49447.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 CCF49447.1 - 0.0085 16.0 0.2 0.036 14.0 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CCF49447.1 - 0.016 15.0 1.4 0.028 14.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 CCF49447.1 - 0.02 15.0 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CCF49447.1 - 0.031 14.1 0.0 0.094 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCF49447.1 - 0.034 13.8 0.0 0.034 13.8 0.0 2.0 2 0 0 2 2 1 0 Archaeal ATPase DUF258 PF03193.11 CCF49447.1 - 0.04 13.1 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CCF49447.1 - 0.042 13.5 0.3 0.096 12.3 0.2 1.6 1 0 0 1 1 1 0 NTPase HLH PF00010.21 CCF49448.1 - 1.5e-17 62.9 0.8 4.3e-17 61.5 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.9 CCF49448.1 - 1.3 6.9 22.7 0.014 13.5 7.2 2.4 2 0 0 2 2 2 0 CDC45-like protein SAPS PF04499.10 CCF49448.1 - 3.1 6.3 9.7 1.1 7.7 1.5 2.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein NIF PF03031.13 CCF49449.1 - 1.4e-51 174.3 0.2 2e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Tcp11 PF05794.8 CCF49450.1 - 1.3e-65 221.8 0.0 7.4e-48 163.3 0.2 4.1 3 1 0 3 3 3 3 T-complex protein 11 Cupin_8 PF13621.1 CCF49451.1 - 1.4e-22 80.4 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCF49451.1 - 1.3e-07 31.1 0.0 2.8e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 CCF49451.1 - 0.0075 16.5 0.0 0.047 13.9 0.0 2.3 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CCF49451.1 - 0.049 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 CCF49451.1 - 0.097 12.3 0.5 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 AraC-like ligand binding domain zf-CCHC PF00098.18 CCF49452.1 - 0.0049 16.7 1.2 0.0049 16.7 0.8 2.0 2 0 0 2 2 2 1 Zinc knuckle PEMT PF04191.8 CCF49453.1 - 8e-33 112.7 4.1 8e-33 112.7 2.8 1.8 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF202 PF02656.10 CCF49453.1 - 1.3 9.3 5.0 71 3.7 3.5 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Hpt PF01627.18 CCF49454.1 - 1.1e-09 38.1 0.1 2.6e-09 36.9 0.1 1.8 1 1 0 1 1 1 1 Hpt domain Paf1 PF03985.8 CCF49454.1 - 0.0056 15.4 13.0 0.0088 14.8 9.0 1.2 1 0 0 1 1 1 1 Paf1 Glypican PF01153.14 CCF49454.1 - 0.043 12.4 3.5 0.054 12.1 2.4 1.1 1 0 0 1 1 1 0 Glypican SusD PF07980.6 CCF49454.1 - 0.08 12.4 1.5 0.11 11.9 1.0 1.3 1 1 0 1 1 1 0 SusD family Lipoprotein_X PF03305.8 CCF49454.1 - 3.8 6.8 9.6 0.69 9.2 4.2 1.5 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein Arrestin_C PF02752.17 CCF49455.1 - 1.4e-12 47.9 3.4 1.9e-11 44.2 1.6 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCF49455.1 - 5.5e-10 39.2 1.7 0.00044 20.0 0.6 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DDHD PF02862.12 CCF49456.1 - 3.7e-47 161.0 0.0 3.7e-47 161.0 0.0 3.6 3 0 0 3 3 3 1 DDHD domain Abhydrolase_6 PF12697.2 CCF49456.1 - 0.019 14.8 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_M24 PF00557.19 CCF49457.1 - 9.9e-27 93.8 0.2 1.6e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 SH3_2 PF07653.12 CCF49457.1 - 0.034 13.6 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Nipped-B_C PF12830.2 CCF49458.1 - 4.5e-48 163.3 0.8 1.3e-47 161.8 0.5 1.9 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CCF49458.1 - 4.7e-08 32.8 1.2 4.7e-08 32.8 0.8 4.0 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 CCF49458.1 - 0.00086 19.1 0.2 0.0031 17.3 0.2 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCF49458.1 - 0.0016 18.3 0.4 2.5 8.4 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat Flg_new PF09479.5 CCF49459.1 - 0.12 12.3 0.3 5.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) PHY PF00360.15 CCF49463.1 - 1.4e-25 89.4 0.0 2.8e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 CCF49463.1 - 3.7e-22 78.1 0.3 1e-21 76.7 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 CCF49463.1 - 4.7e-16 59.2 0.0 1.5e-15 57.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 CCF49463.1 - 2.8e-15 56.2 0.1 1.5e-14 53.9 0.1 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCF49463.1 - 1.9e-12 46.9 0.7 7.7e-12 45.0 0.5 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 CCF49463.1 - 8.1e-09 35.9 0.0 2.4e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold Hist_deacetyl PF00850.14 CCF49467.1 - 3.8e-60 203.7 7.0 2.2e-59 201.2 4.8 2.0 1 1 0 1 1 1 1 Histone deacetylase domain RIO1 PF01163.17 CCF49468.1 - 2.5e-65 219.3 0.0 2.5e-65 219.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family RhoGAP PF00620.22 CCF49469.1 - 3.1e-08 33.3 0.0 1.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 CCF49469.1 - 0.00011 22.2 0.0 0.0016 18.5 0.0 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pkinase PF00069.20 CCF49470.1 - 8.6e-65 218.4 0.0 5.3e-64 215.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49470.1 - 2.8e-33 115.0 0.0 4.7e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CCF49470.1 - 2.9e-25 87.7 16.1 3.6e-14 52.2 7.1 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CCF49470.1 - 2.4e-20 71.9 26.3 7.3e-11 41.6 6.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CCF49470.1 - 8e-08 32.6 0.9 2.3e-07 31.2 0.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCF49470.1 - 0.0095 14.9 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 CCF49470.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 C2 domain Uds1 PF15456.1 CCF49470.1 - 0.24 11.3 9.9 0.33 10.9 2.0 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Asp PF00026.18 CCF49471.1 - 2.2e-17 63.2 0.0 6.8e-16 58.4 0.0 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF4381 PF14316.1 CCF49471.1 - 2.6 8.1 6.6 0.19 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2839 PF10999.3 CCF49472.1 - 0.6 10.1 2.8 3.4 7.7 1.9 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) ADH_N PF08240.7 CCF49473.1 - 6.1e-32 109.6 0.2 1.1e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF49473.1 - 2.1e-20 72.5 0.1 4.3e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CCF49473.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.1 CCF49473.1 - 0.029 14.0 0.0 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 CCF49473.1 - 0.03 14.3 0.1 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ras PF00071.17 CCF49475.1 - 1.9e-56 189.9 0.0 2.2e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF49475.1 - 7.3e-16 58.7 0.0 9.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF49475.1 - 1e-06 28.1 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCF49475.1 - 0.0002 20.6 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCF49475.1 - 0.058 12.5 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ThiF PF00899.16 CCF49476.1 - 3.8e-36 123.8 0.3 6.7e-36 123.1 0.0 1.5 2 0 0 2 2 2 1 ThiF family DAO PF01266.19 CCF49476.1 - 0.029 13.2 0.1 0.056 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCF49476.1 - 0.039 13.0 0.1 0.065 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain PHZA_PHZB PF03284.8 CCF49476.1 - 0.06 12.4 0.6 0.27 10.2 0.0 2.2 3 0 0 3 3 3 0 Phenazine biosynthesis protein A/B ApbA PF02558.11 CCF49476.1 - 0.097 12.1 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 CCF49476.1 - 0.18 10.7 0.1 0.6 9.0 0.0 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase ILVD_EDD PF00920.16 CCF49477.1 - 1.3e-192 640.8 0.9 1.5e-192 640.6 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Pro-rich PF15240.1 CCF49478.1 - 0.025 14.6 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Proline-rich AWPM-19 PF05512.6 CCF49478.1 - 0.72 9.8 8.7 0.05 13.6 2.3 1.7 2 0 0 2 2 2 0 AWPM-19-like family DUF788 PF05620.6 CCF49479.1 - 5.4e-42 143.5 1.0 7e-42 143.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DEC-1_N PF04625.8 CCF49480.1 - 0.014 14.1 2.5 0.017 13.8 1.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OB_NTP_bind PF07717.11 CCF49481.1 - 6.1e-28 96.9 0.1 1.4e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCF49481.1 - 3.8e-27 94.2 0.0 2.1e-24 85.4 0.0 3.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF49481.1 - 1.6e-14 53.4 0.0 4.2e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF49481.1 - 1.2e-07 31.3 0.0 3.7e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF49481.1 - 2e-05 24.7 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCF49481.1 - 0.00014 20.8 0.0 0.00027 19.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 CCF49481.1 - 0.0021 17.5 0.1 0.0064 15.9 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CCF49481.1 - 0.0091 15.4 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 CCF49481.1 - 0.014 15.1 1.3 0.04 13.6 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 CCF49481.1 - 0.021 13.6 0.0 0.1 11.4 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.10 CCF49481.1 - 0.024 14.4 0.6 4.7 6.9 0.0 3.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCF49481.1 - 0.035 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_14 PF13173.1 CCF49481.1 - 0.18 11.6 1.4 3.2 7.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CCF49481.1 - 0.21 11.1 5.4 1.9 7.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Atg14 PF10186.4 CCF49482.1 - 9.6e-21 74.0 4.6 7.5e-12 44.8 0.0 2.8 2 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 zf-rbx1 PF12678.2 CCF49485.1 - 3.2e-35 120.0 15.9 3.9e-35 119.7 11.0 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCF49485.1 - 1e-17 63.7 12.2 1.4e-17 63.2 8.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CCF49485.1 - 6.6e-07 29.0 15.7 9.9e-07 28.4 8.9 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCF49485.1 - 8.5e-05 22.1 9.8 0.026 14.2 6.6 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF49485.1 - 0.00033 20.2 12.2 0.0036 16.9 8.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF49485.1 - 0.015 15.2 14.1 0.38 10.8 9.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) VSP PF03302.8 CCF49485.1 - 0.041 12.5 3.6 0.044 12.4 2.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-RING_5 PF14634.1 CCF49485.1 - 0.097 12.4 11.8 0.64 9.7 8.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CCF49485.1 - 0.32 10.9 14.3 0.066 13.1 6.2 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CCF49485.1 - 0.6 9.8 7.6 20 5.0 5.3 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CCF49485.1 - 1.2 9.1 12.0 2.8 7.9 8.3 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCF49485.1 - 4.8 7.3 13.8 1.6e+02 2.4 9.6 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.1 CCF49485.1 - 8.7 6.3 9.2 0.44 10.4 0.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING WD40 PF00400.27 CCF49486.1 - 5.6e-39 130.6 35.2 4.2e-06 26.4 0.1 11.5 13 0 0 13 13 13 9 WD domain, G-beta repeat CTP_transf_2 PF01467.21 CCF49486.1 - 3.9e-07 30.2 0.0 9.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase UPF0183 PF03676.9 CCF49487.1 - 0.044 12.3 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) ATE_C PF04377.10 CCF49489.1 - 8.1e-45 152.0 0.1 1.4e-44 151.2 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CCF49489.1 - 1.8e-24 85.3 0.3 3.6e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Kelch_2 PF07646.10 CCF49489.1 - 0.042 13.6 0.2 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 Kelch motif DSS1_SEM1 PF05160.8 CCF49490.1 - 3.9e-18 64.9 10.6 8.8e-12 44.6 1.2 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family WD40 PF00400.27 CCF49491.1 - 6.4e-15 54.3 12.0 0.019 14.8 0.0 6.6 5 1 1 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 CCF49491.1 - 9.6e-08 31.9 0.0 3.2e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 CCF49491.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Prp18 domain rve PF00665.21 CCF49492.1 - 5.6e-16 58.7 0.1 1e-15 57.8 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1681 PF07933.9 CCF49495.1 - 3.2e-57 192.5 0.0 3.9e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF3712 PF12505.3 CCF49496.1 - 1.2e-31 109.2 0.1 1.4e-20 73.5 0.0 5.7 6 1 0 6 6 6 3 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CCF49496.1 - 3.1e-05 24.2 0.0 0.074 13.4 0.0 3.9 2 0 0 2 2 2 2 Late embryogenesis abundant protein RVT_2 PF07727.9 CCF49498.1 - 4.9e-56 189.4 0.0 6e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49499.1 - 0.049 13.7 0.1 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain rve_3 PF13683.1 CCF49499.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_4 PF14392.1 CCF49500.1 - 2.3 7.9 7.4 4.5 7.0 5.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Apc4 PF12896.2 CCF49502.1 - 8.1e-34 116.7 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ETF PF01012.16 CCF49503.1 - 8.9e-41 139.3 0.1 1.7e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CCF49503.1 - 2.1e-35 120.1 0.1 5.6e-35 118.8 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain HAUS5 PF14817.1 CCF49503.1 - 0.19 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DHH PF01368.15 CCF49504.1 - 8.2e-05 22.2 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 DHH family Raffinose_syn PF05691.7 CCF49504.1 - 0.13 9.7 0.1 0.17 9.3 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Ion_trans_N PF08412.5 CCF49504.1 - 0.16 11.2 0.0 0.41 9.9 0.0 1.6 1 0 0 1 1 1 0 Ion transport protein N-terminal Ku PF02735.11 CCF49505.1 - 3.9e-19 68.8 0.1 7.2e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CCF49505.1 - 2.6e-12 46.7 0.9 1.2e-11 44.5 0.3 2.2 2 0 0 2 2 2 1 Ku C terminal domain like VWA_2 PF13519.1 CCF49505.1 - 0.0018 18.4 0.0 0.0048 17.0 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Isochorismatase PF00857.15 CCF49506.1 - 8.6e-29 100.6 0.1 1.1e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family zf-ZPR1 PF03367.8 CCF49506.1 - 0.017 14.2 0.1 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain SIR2 PF02146.12 CCF49507.1 - 2.1e-25 89.5 0.0 3.1e-20 72.6 0.0 3.3 3 0 0 3 3 3 2 Sir2 family Rdx PF10262.4 CCF49508.1 - 7.2e-21 74.0 0.0 1e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Rdx family RVT_2 PF07727.9 CCF49512.1 - 3.8e-08 32.5 0.1 4.7e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CNP1 PF08750.6 CCF49512.1 - 0.038 13.6 0.2 0.048 13.3 0.2 1.2 1 0 0 1 1 1 0 CNP1-like family WW PF00397.21 CCF49513.1 - 4.8 7.1 7.5 0.27 11.1 0.6 2.4 3 0 0 3 3 3 0 WW domain EB1 PF03271.12 CCF49514.1 - 9.8e-17 60.7 0.2 1.8e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CCF49514.1 - 5.1e-06 26.4 0.1 1.2e-05 25.3 0.1 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain GOLGA2L5 PF15070.1 CCF49514.1 - 0.057 11.9 0.1 0.16 10.4 0.0 1.6 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Homeobox PF00046.24 CCF49515.1 - 3.1e-13 49.1 1.6 7.6e-13 47.8 1.1 1.7 1 0 0 1 1 1 1 Homeobox domain DUF2267 PF10025.4 CCF49515.1 - 0.1 12.6 0.7 0.26 11.3 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Homeobox_KN PF05920.6 CCF49515.1 - 0.33 10.7 0.1 0.33 10.7 0.1 2.8 3 0 0 3 3 3 0 Homeobox KN domain API5 PF05918.6 CCF49516.1 - 1.8 7.0 5.7 1.9 6.8 4.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Mito_carr PF00153.22 CCF49517.1 - 8.9e-32 108.6 6.9 2.7e-14 52.6 0.0 3.2 2 1 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb2_6 PF00562.23 CCF49517.1 - 0.049 12.3 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Glyco_hydro_9 PF00759.14 CCF49517.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 NAD_binding_8 PF13450.1 CCF49518.1 - 1.7e-09 37.5 0.0 3.2e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCF49518.1 - 0.049 12.6 0.1 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2009 PF09418.5 CCF49518.1 - 0.13 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) HA2 PF04408.18 CCF49519.1 - 4.8e-17 61.8 0.0 1.9e-16 59.9 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF49519.1 - 2.1e-12 46.7 0.2 4.5e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 CCF49519.1 - 8.8e-08 32.6 0.2 0.0027 18.2 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 CCF49519.1 - 1.4e-06 27.8 0.2 3.3e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase API5 PF05918.6 CCF49519.1 - 0.11 10.9 13.8 0.22 9.9 9.6 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fungal_trans PF04082.13 CCF49520.1 - 1e-08 34.3 0.2 2.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF49520.1 - 0.01 15.7 9.2 0.024 14.5 6.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_I PF04597.9 CCF49521.1 - 2.4e-114 382.2 0.0 2.8e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CDC45 PF02724.9 CCF49522.1 - 6e-211 701.7 0.0 6.9e-211 701.5 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2201_N PF13203.1 CCF49522.1 - 0.001 18.2 0.1 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative metallopeptidase domain LeuA_dimer PF08502.5 CCF49522.1 - 0.024 14.4 0.0 9.9 5.9 0.0 2.5 2 0 0 2 2 2 0 LeuA allosteric (dimerisation) domain KdpC PF02669.10 CCF49522.1 - 0.045 13.4 1.1 0.096 12.3 0.4 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain RVT_2 PF07727.9 CCF49523.1 - 0.019 13.9 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_TL5_C PF14693.1 CCF49524.1 - 0.13 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain RasGEF PF00617.14 CCF49525.1 - 1.4e-45 155.3 0.0 2.4e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCF49525.1 - 1.3e-06 28.4 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 CCF49525.1 - 0.00024 21.6 0.0 0.00054 20.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF49525.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.17 CCF49525.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.6 1 1 0 1 1 1 0 Ras family MobB PF03205.9 CCF49525.1 - 0.16 11.6 0.1 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aminotran_5 PF00266.14 CCF49526.1 - 4.1e-89 298.9 0.0 1.1e-88 297.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCF49526.1 - 3.5e-06 26.3 0.0 5.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CCF49526.1 - 0.048 11.9 0.0 0.075 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S24e PF01282.14 CCF49526.1 - 0.066 13.0 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S24e AroM PF07302.6 CCF49526.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 AroM protein DUF1212 PF06738.7 CCF49527.1 - 1.3e-42 145.5 0.9 1.3e-42 145.5 0.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 CCF49527.1 - 1.8e-17 63.5 5.0 1.8e-17 63.5 3.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) WLM PF08325.5 CCF49528.1 - 0.13 12.0 1.1 0.19 11.5 0.8 1.2 1 0 0 1 1 1 0 WLM domain Ribosomal_L22 PF00237.14 CCF49529.1 - 3.3e-21 75.2 0.1 8.8e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PGM_PMM_III PF02880.11 CCF49529.1 - 0.098 12.7 0.0 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DDE_Tnp_ISL3 PF01610.12 CCF49530.1 - 0.077 12.5 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF2203 PF09969.4 CCF49530.1 - 0.14 12.3 1.0 0.28 11.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_60s PF00428.14 CCF49530.1 - 1.4 9.3 6.4 13 6.2 0.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_90 PF05686.7 CCF49532.1 - 7.6e-15 54.4 1.6 1.3e-13 50.4 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Acyl_transf_3 PF01757.17 CCF49533.1 - 1.7e-12 46.8 30.3 2.9e-12 46.0 21.0 1.3 1 1 0 1 1 1 1 Acyltransferase family LEAP-2 PF07359.6 CCF49533.1 - 0.18 11.4 0.8 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nuc_sug_transp PF04142.10 CCF49534.1 - 2.4e-42 144.7 8.6 2.4e-42 144.7 6.0 1.7 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CCF49534.1 - 1e-05 25.6 0.2 1e-05 25.6 0.1 3.5 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 CCF49534.1 - 5.6e-05 22.8 0.7 5.6e-05 22.8 0.5 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCF49534.1 - 0.0031 17.5 4.0 0.0031 17.5 2.8 3.6 3 1 0 3 3 3 2 EamA-like transporter family Multi_Drug_Res PF00893.14 CCF49534.1 - 0.061 13.8 1.0 0.061 13.8 0.7 3.2 3 0 0 3 3 3 0 Small Multidrug Resistance protein UPF0546 PF10639.4 CCF49534.1 - 0.49 10.2 7.6 1.4 8.7 1.2 3.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0546 Acetyltransf_1 PF00583.19 CCF49537.1 - 2.5e-18 65.8 0.0 3.5e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF49537.1 - 2e-09 37.5 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCF49537.1 - 3.4e-07 30.5 0.0 3.9e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF49537.1 - 1.3e-06 28.4 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCF49537.1 - 1.5e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 CCF49537.1 - 2e-05 24.4 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF49537.1 - 0.00091 19.1 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF49537.1 - 0.0035 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CCF49537.1 - 0.047 13.5 0.0 0.082 12.7 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 CCF49537.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4203 PF13886.1 CCF49537.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Fungal_trans PF04082.13 CCF49538.1 - 1.8e-12 46.7 1.0 2.9e-12 46.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAP PF02037.22 CCF49540.1 - 0.00013 21.3 0.1 0.00038 19.8 0.0 1.9 1 0 0 1 1 1 1 SAP domain Phage_tail_L PF05100.7 CCF49540.1 - 0.032 13.3 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein L zf-C2H2_4 PF13894.1 CCF49540.1 - 0.29 11.5 0.2 0.29 11.5 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.7 CCF49540.1 - 1.1 9.4 7.2 0.13 12.3 0.8 2.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding SNF2_N PF00176.18 CCF49541.1 - 4.7e-67 225.8 0.2 7.8e-67 225.1 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCF49541.1 - 1.5e-27 95.7 0.7 1.5e-27 95.7 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCF49541.1 - 9.6e-19 66.8 0.7 7.2e-13 47.9 0.1 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCF49541.1 - 1.1e-14 54.0 0.0 1.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GFA PF04828.9 CCF49543.1 - 6.6e-11 42.0 2.9 1.2e-10 41.1 2.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1087 PF06465.8 CCF49543.1 - 0.16 11.8 0.2 0.31 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Cys_rich_CWC PF14375.1 CCF49543.1 - 0.23 11.4 5.3 0.75 9.7 3.7 1.9 1 0 0 1 1 1 0 Cysteine-rich CWC Herpes_glycop_D PF01537.12 CCF49544.1 - 0.013 15.4 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain ATP-synt PF00231.14 CCF49545.1 - 5.3e-73 245.8 3.8 6.3e-73 245.6 2.6 1.0 1 0 0 1 1 1 1 ATP synthase Vps16_C PF04840.7 CCF49545.1 - 0.032 13.1 3.0 0.42 9.4 0.1 2.1 2 0 0 2 2 2 0 Vps16, C-terminal region eIF-5_eIF-2B PF01873.12 CCF49546.1 - 2.4e-47 159.7 0.5 3.7e-47 159.0 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Hid1 PF12722.2 CCF49546.1 - 0.088 10.4 6.7 0.1 10.2 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Lar_restr_allev PF14354.1 CCF49546.1 - 0.1 12.9 0.2 0.33 11.2 0.2 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 CCF49546.1 - 0.13 12.1 1.3 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Zinc ribbon domain RVT_2 PF07727.9 CCF49547.1 - 2.6e-61 206.7 0.3 3.2e-61 206.4 0.2 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1810 PF08837.6 CCF49548.1 - 0.038 13.5 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) ABC_membrane PF00664.18 CCF49549.1 - 1e-67 228.4 17.2 1e-38 133.3 3.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF49549.1 - 3.8e-61 205.3 0.0 1.2e-30 106.6 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF49549.1 - 1.3e-12 47.4 1.1 0.0023 17.1 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 CCF49549.1 - 2e-09 36.5 0.0 0.0021 16.7 0.0 3.2 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 CCF49549.1 - 2.1e-09 37.7 0.0 0.032 14.1 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF49549.1 - 9e-09 34.7 0.8 0.00098 18.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CCF49549.1 - 1.4e-08 34.0 0.0 0.00047 19.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCF49549.1 - 1.8e-08 35.2 0.0 0.004 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF49549.1 - 4.6e-07 30.0 2.3 0.015 15.2 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 CCF49549.1 - 6.4e-06 26.5 0.0 0.04 14.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCF49549.1 - 7.4e-06 26.1 3.4 0.015 15.4 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CCF49549.1 - 1.2e-05 24.8 0.0 0.047 13.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CCF49549.1 - 8.8e-05 22.4 0.0 0.063 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCF49549.1 - 0.00029 20.6 1.5 0.73 9.7 0.1 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CCF49549.1 - 0.00044 20.6 4.6 0.0064 16.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 CCF49549.1 - 0.0051 16.5 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 CCF49549.1 - 0.0058 15.2 2.0 0.021 13.3 1.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_10 PF12846.2 CCF49549.1 - 0.0068 15.8 2.5 1.6 8.0 0.0 3.3 4 0 0 4 4 3 1 AAA-like domain MMR_HSR1 PF01926.18 CCF49549.1 - 0.017 15.0 0.1 2 8.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CCF49549.1 - 0.028 13.5 0.0 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 CCF49549.1 - 0.039 13.7 1.4 2 8.1 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 CCF49549.1 - 0.048 13.3 0.0 2 8.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCF49549.1 - 0.051 13.4 0.1 0.8 9.6 0.0 2.9 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.1 CCF49549.1 - 0.061 12.3 0.0 0.43 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CCF49549.1 - 0.084 13.0 0.0 4.7 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CCF49549.1 - 0.089 12.7 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 CCF49549.1 - 0.091 12.3 0.1 7.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Gtr1_RagA PF04670.7 CCF49549.1 - 0.19 10.8 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Asp PF00026.18 CCF49550.1 - 1.7e-29 103.0 0.0 2.1e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF49550.1 - 0.00013 21.9 0.0 0.0027 17.6 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TPR_11 PF13414.1 CCF49552.1 - 2.8e-25 87.7 7.2 1.8e-13 49.8 0.0 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCF49552.1 - 9.3e-20 69.3 3.0 0.0001 21.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF49552.1 - 3e-15 54.8 6.3 0.0004 20.0 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCF49552.1 - 1.1e-12 47.0 5.7 0.0048 17.0 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49552.1 - 1.2e-12 48.1 4.7 4.6e-06 27.1 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCF49552.1 - 7.4e-12 44.7 3.5 0.0075 16.8 0.0 5.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF49552.1 - 8.9e-12 44.7 7.4 7.5e-07 29.0 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCF49552.1 - 2.7e-09 36.1 1.8 0.045 13.5 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF49552.1 - 3.4e-07 30.4 12.2 0.0095 16.2 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCF49552.1 - 5.8e-07 28.8 1.7 0.81 9.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCF49552.1 - 1.4e-05 24.8 1.9 0.024 14.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF49552.1 - 5.3e-05 23.2 4.9 0.014 15.4 0.6 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CCF49552.1 - 0.0071 16.1 0.0 2.4 8.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCF49552.1 - 0.26 11.2 2.7 5 7.2 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCF49552.1 - 2.7 8.1 14.4 0.58 10.3 1.2 4.7 3 2 1 5 5 5 0 Tetratricopeptide repeat RPEL PF02755.10 CCF49553.1 - 2.3e-26 90.3 31.4 1.8e-09 36.6 0.6 5.0 5 0 0 5 5 5 4 RPEL repeat DnaI_N PF07319.6 CCF49553.1 - 0.019 15.2 1.9 3.4 7.9 0.2 2.8 1 1 2 3 3 3 0 Primosomal protein DnaI N-terminus Antimicrobial18 PF08130.6 CCF49553.1 - 0.032 14.0 1.1 18 5.2 0.1 3.3 3 0 0 3 3 3 0 Type A lantibiotic family DUF1992 PF09350.5 CCF49553.1 - 0.044 13.6 6.1 2.5 7.9 0.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1992) Phe_tRNA-synt_N PF02912.13 CCF49553.1 - 1.8 8.3 8.8 4.3 7.1 0.5 3.4 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Topoisom_I_N PF02919.10 CCF49554.1 - 1.2e-83 279.6 1.7 1.2e-83 279.6 1.2 3.8 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCF49554.1 - 3.3e-67 226.0 3.2 3.3e-67 226.0 2.2 2.4 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCF49554.1 - 9.1e-16 57.2 0.6 1e-11 44.3 0.1 2.9 2 0 0 2 2 2 2 C-terminal topoisomerase domain NDUF_B12 PF08122.7 CCF49555.1 - 6.6e-22 76.9 1.1 7.4e-22 76.8 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ATP-sulfurylase PF01747.12 CCF49556.1 - 1.6e-86 289.0 0.3 2.3e-86 288.5 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 CCF49556.1 - 3.4e-55 186.0 0.0 5.2e-55 185.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 CCF49556.1 - 2.1e-51 173.5 0.0 3.5e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Mito_carr PF00153.22 CCF49557.1 - 6.5e-47 157.1 9.5 9.8e-19 66.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med12 PF09497.5 CCF49558.1 - 9e-30 102.4 0.1 8.4e-29 99.3 0.0 2.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 CCF49558.1 - 0.0026 16.3 0.0 0.016 13.7 0.0 2.1 2 1 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain tRNA-synt_1 PF00133.17 CCF49559.1 - 3.4e-37 127.7 0.0 8.6e-29 99.9 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCF49559.1 - 1.3e-18 66.8 0.0 8.9e-11 41.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCF49559.1 - 5.2e-13 49.0 0.1 1.4e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCF49559.1 - 2e-06 27.1 0.0 4.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Peptidase_M14 PF00246.19 CCF49560.1 - 2.5e-61 207.7 0.0 2.8e-43 148.5 0.0 2.1 2 0 0 2 2 2 2 Zinc carboxypeptidase Prefoldin_3 PF13758.1 CCF49560.1 - 0.073 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF4013 PF13197.1 CCF49560.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) WD40 PF00400.27 CCF49561.1 - 1.7e-84 274.9 20.8 1.3e-08 34.3 0.0 11.9 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 CCF49561.1 - 4.3e-28 97.7 0.1 2.7e-21 75.6 0.0 2.4 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCF49561.1 - 5.3e-05 21.5 6.9 1.3 7.1 0.0 5.8 5 2 1 6 6 6 4 Nucleoporin Nup120/160 tRNA-synt_1b PF00579.20 CCF49562.1 - 1.8e-65 221.0 0.0 2.4e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CCF49562.1 - 7.6e-05 22.0 0.0 0.00018 20.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCF49562.1 - 0.065 12.8 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 S4 domain MMR_HSR1 PF01926.18 CCF49563.1 - 8.8e-19 67.5 0.1 1.9e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF49563.1 - 7.9e-10 38.2 0.0 7.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCF49563.1 - 1.2e-05 24.8 0.9 0.0017 17.8 0.0 3.6 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCF49563.1 - 0.00019 21.3 0.7 0.021 14.6 0.1 2.8 2 2 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CCF49563.1 - 0.0048 16.0 0.1 0.014 14.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CCF49563.1 - 0.011 16.2 0.1 0.16 12.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PALP PF00291.20 CCF49564.1 - 1.5e-77 260.8 0.8 2e-77 260.4 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CCF49564.1 - 3.9e-44 148.1 0.1 5.2e-27 93.2 0.0 3.6 4 0 0 4 4 4 3 C-terminal regulatory domain of Threonine dehydratase ABC_membrane PF00664.18 CCF49565.1 - 1.1e-78 264.4 28.4 2e-42 145.4 7.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF49565.1 - 1.7e-62 209.7 0.2 4e-32 111.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF49565.1 - 4.2e-12 45.7 1.3 0.00035 19.8 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF49565.1 - 1.1e-09 38.6 0.2 0.13 12.2 0.0 4.2 3 1 1 4 4 4 3 AAA domain ABC_ATPase PF09818.4 CCF49565.1 - 3.7e-08 32.3 0.1 6.6e-05 21.6 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 CCF49565.1 - 1.8e-06 27.4 0.2 0.37 10.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CCF49565.1 - 2.2e-06 27.8 2.7 0.33 11.0 0.0 4.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF49565.1 - 1.3e-05 24.5 1.1 0.099 12.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCF49565.1 - 1.7e-05 25.6 0.0 0.015 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCF49565.1 - 3e-05 23.8 4.3 0.085 12.7 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CCF49565.1 - 0.00057 19.0 0.7 0.056 12.5 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin AAA_33 PF13671.1 CCF49565.1 - 0.0013 18.6 0.2 0.42 10.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCF49565.1 - 0.0017 17.5 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCF49565.1 - 0.0024 18.1 0.1 1.2 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 CCF49565.1 - 0.0031 16.7 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MobB PF03205.9 CCF49565.1 - 0.0075 15.9 0.1 5.7 6.6 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 CCF49565.1 - 0.0094 14.6 0.6 0.71 8.4 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_10 PF12846.2 CCF49565.1 - 0.013 14.9 1.2 3 7.1 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain AAA_5 PF07728.9 CCF49565.1 - 0.016 14.8 0.0 1.1 9.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CENP-L PF13092.1 CCF49565.1 - 0.041 13.6 0.0 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 APS_kinase PF01583.15 CCF49565.1 - 0.068 12.8 0.4 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 CCF49565.1 - 0.08 13.2 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CCF49565.1 - 0.43 10.3 6.4 2.5 7.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 PRK PF00485.13 CCF49565.1 - 0.46 10.0 1.5 23 4.4 0.0 2.7 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 CCF49565.1 - 0.77 8.7 0.0 1.8 7.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain LRR_4 PF12799.2 CCF49566.1 - 4.4e-13 48.5 25.2 1.8e-05 24.1 2.4 4.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF49566.1 - 5.3e-13 48.5 10.5 1.6e-08 34.1 4.9 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CCF49566.1 - 3.1e-05 23.5 13.7 0.75 10.0 0.3 6.1 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CCF49566.1 - 3.4e-05 23.2 20.4 0.028 14.4 1.2 6.0 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 CCF49566.1 - 0.042 13.4 0.1 0.12 11.9 0.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 CCF49566.1 - 0.31 11.4 14.6 36 5.1 0.7 5.6 5 0 0 5 5 5 0 Leucine rich repeat DUF966 PF06136.8 CCF49566.1 - 8.8 5.6 12.7 5 6.4 6.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF966) EF_TS PF00889.14 CCF49567.1 - 1.4e-17 63.7 0.6 3.6e-15 55.9 0.0 3.0 2 1 1 3 3 3 2 Elongation factor TS POT1 PF02765.12 CCF49568.1 - 2.7e-19 69.5 0.0 2.6e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DZR PF12773.2 CCF49568.1 - 0.022 14.5 1.4 0.057 13.2 1.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon tRNA_anti-codon PF01336.20 CCF49568.1 - 0.081 12.7 0.2 2.3 8.1 0.0 3.1 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain zinc_ribbon_2 PF13240.1 CCF49568.1 - 0.32 10.5 1.7 0.72 9.4 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-4CXXC_R1 PF10497.4 CCF49569.1 - 2.3e-06 27.6 12.7 0.00042 20.3 8.8 2.9 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Hamartin PF04388.7 CCF49570.1 - 2e-37 129.2 8.1 2e-37 129.2 5.6 2.9 3 1 0 3 3 3 1 Hamartin protein HALZ PF02183.13 CCF49570.1 - 0.011 15.4 10.3 0.25 11.0 0.3 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper BLOC1_2 PF10046.4 CCF49570.1 - 0.17 12.0 2.4 0.94 9.6 0.6 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 CCF49570.1 - 0.19 11.7 16.7 1.9 8.5 0.2 5.3 5 0 0 5 5 5 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 CCF49570.1 - 0.21 11.4 31.9 0.42 10.4 3.8 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 CCF49570.1 - 0.66 9.8 21.4 3.1 7.6 1.6 4.3 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 CCF49570.1 - 1 9.2 3.3 31 4.5 0.0 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 CCF49570.1 - 4.6 5.8 14.4 0.19 10.4 5.1 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Pyridoxal_deC PF00282.14 CCF49571.1 - 8.3e-22 77.1 0.0 1.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCF49571.1 - 4.2e-09 35.6 0.0 8.2e-09 34.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CCF49571.1 - 0.00053 19.1 0.1 0.0012 18.0 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCF49571.1 - 0.03 12.6 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aldo_ket_red PF00248.16 CCF49572.1 - 2.1e-40 138.3 0.0 2.9e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ERp29_N PF07912.8 CCF49572.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 ERp29, N-terminal domain tRNA-synt_2 PF00152.15 CCF49573.1 - 5.3e-86 288.4 0.0 7e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCF49573.1 - 1.3e-11 44.1 0.0 3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCF49573.1 - 2.2e-08 33.5 0.0 6.8e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCF49573.1 - 0.0038 16.8 0.1 0.73 9.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_60s PF00428.14 CCF49573.1 - 4.5 7.7 16.9 6.9 7.1 7.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sugar_tr PF00083.19 CCF49574.1 - 9.2e-32 110.1 23.3 2.5e-25 88.9 4.0 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF49574.1 - 1e-24 86.9 29.3 2e-24 86.0 20.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily G-alpha PF00503.15 CCF49575.1 - 3.1e-130 434.3 0.6 3.7e-130 434.1 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCF49575.1 - 2.7e-17 62.5 0.4 4.9e-12 45.4 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF49575.1 - 6.6e-05 22.1 5.8 0.00036 19.7 0.3 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF49575.1 - 8.2e-05 23.0 0.1 0.38 11.2 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein zf-CHC2 PF01807.15 CCF49575.1 - 0.001 18.5 0.1 0.0039 16.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger MMR_HSR1 PF01926.18 CCF49575.1 - 0.0039 17.1 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CCF49575.1 - 0.0073 15.8 0.1 0.036 13.5 0.1 2.0 1 1 1 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 CCF49575.1 - 0.017 14.5 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 CCF49575.1 - 0.03 13.7 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.1 CCF49575.1 - 0.042 12.8 0.3 0.079 11.9 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain Capsid-VNN PF11729.3 CCF49576.1 - 0.97 8.3 7.2 1.2 8.0 5.0 1.1 1 0 0 1 1 1 0 nodavirus capsid protein Menin PF05053.8 CCF49576.1 - 1.1 7.3 6.7 1.3 7.1 4.7 1.0 1 0 0 1 1 1 0 Menin tRNA-synt_1c PF00749.16 CCF49577.1 - 1.7e-103 345.6 0.0 2.9e-103 344.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CCF49577.1 - 2.8e-41 140.8 0.0 4.6e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CCF49577.1 - 1.3e-32 112.8 0.0 3e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CCF49577.1 - 2.4e-15 56.9 3.7 2.4e-15 56.9 2.6 3.4 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Nol1_Nop2_Fmu PF01189.12 CCF49578.1 - 1e-30 107.0 0.0 7.5e-19 68.1 0.0 3.8 2 1 1 3 3 3 3 NOL1/NOP2/sun family Pribosyltran PF00156.22 CCF49578.1 - 1.6e-14 53.6 0.1 3.1e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CDC73 PF05179.9 CCF49579.1 - 1.5e-45 155.6 9.7 3e-45 154.6 6.7 1.5 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Mito_fiss_reg PF05308.6 CCF49579.1 - 0.0051 16.2 1.6 0.012 15.0 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial fission regulator CAP_N PF01213.14 CCF49579.1 - 0.3 10.3 4.5 0.55 9.4 3.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TSA PF03249.8 CCF49579.1 - 0.49 8.8 7.6 0.75 8.2 5.3 1.2 1 0 0 1 1 1 0 Type specific antigen PAT1 PF09770.4 CCF49579.1 - 3.9 5.5 12.2 5.5 5.0 8.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0197 PF05251.7 CCF49581.1 - 1e-06 28.9 3.1 1.3e-06 28.5 2.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) VIT1 PF01988.14 CCF49581.1 - 1.4 8.4 4.6 1.5 8.2 3.2 1.0 1 0 0 1 1 1 0 VIT family PEPCK_ATP PF01293.15 CCF49582.1 - 9.4e-222 736.5 0.0 1.1e-221 736.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CCF49582.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 CCF49583.1 - 3.1e-45 154.3 0.1 4.3e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF49583.1 - 0.00076 20.3 0.1 0.0024 18.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Na_Ca_ex PF01699.19 CCF49584.1 - 1.5e-39 134.8 42.4 2.3e-21 75.8 10.9 3.1 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF1385 PF07136.6 CCF49584.1 - 0.011 14.7 0.1 0.011 14.7 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1385) SH PF01445.12 CCF49584.1 - 0.015 14.9 0.2 0.099 12.3 0.2 2.5 1 0 0 1 1 1 0 Viral small hydrophobic protein Brevenin PF03032.10 CCF49584.1 - 1.6 8.6 3.8 2.1 8.2 0.2 2.8 2 0 0 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family DUF3684 PF12449.3 CCF49585.1 - 0 1304.6 0.0 0 1304.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 CCF49585.1 - 0.084 12.5 0.0 0.32 10.6 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serglycin PF04360.7 CCF49585.1 - 0.12 12.1 11.4 0.15 11.7 2.3 2.9 3 0 0 3 3 3 0 Serglycin MPC PF03650.8 CCF49586.1 - 2.9e-39 133.7 0.2 3.4e-39 133.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Zn_clus PF00172.13 CCF49587.1 - 3.6e-08 33.1 11.5 7.6e-08 32.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF49587.1 - 0.00062 18.7 0.5 0.0055 15.6 0.0 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ribosomal_S2 PF00318.15 CCF49588.1 - 4.5e-43 146.9 0.0 8.6e-21 74.1 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 MUG113 PF13455.1 CCF49589.1 - 2.9e-19 69.2 0.2 1.3e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CCF49589.1 - 3.7e-12 46.5 0.2 2.2e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain Ribosomal_S5 PF00333.15 CCF49590.1 - 7.9e-28 95.9 2.9 1.8e-27 94.8 0.8 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCF49590.1 - 8.7e-22 76.2 0.0 1.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain F1F0-ATPsyn_F PF10791.4 CCF49591.1 - 5.1e-34 116.3 0.0 6.5e-34 116.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi IMS PF00817.15 CCF49592.1 - 4.7e-45 153.0 0.1 8.5e-45 152.1 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCF49592.1 - 1.2e-15 57.5 2.0 2.6e-15 56.5 1.4 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CCF49592.1 - 4.5e-06 26.3 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif UIM PF02809.15 CCF49592.1 - 0.17 11.5 4.6 0.062 12.9 1.1 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Peptidase_C54 PF03416.14 CCF49593.1 - 1.1e-85 287.2 0.0 2.7e-85 285.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family C54 NAP PF00956.13 CCF49594.1 - 1e-86 290.0 4.8 1e-86 290.0 3.3 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TCO89 PF10452.4 CCF49594.1 - 0.14 10.9 6.4 0.23 10.2 4.4 1.3 1 0 0 1 1 1 0 TORC1 subunit TCO89 zf-C2H2 PF00096.21 CCF49595.1 - 1.2e-11 44.1 18.9 0.0003 20.9 0.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF49595.1 - 1.9e-09 37.1 15.8 0.00062 19.9 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF49595.1 - 5.7e-09 35.8 11.0 0.0012 18.9 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCF49595.1 - 0.00032 20.4 5.9 0.13 12.2 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4175 PF13779.1 CCF49595.1 - 0.62 7.6 31.1 0.92 7.1 21.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FimP PF09766.4 CCF49595.1 - 0.74 8.8 18.8 1.2 8.1 13.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CCF49595.1 - 1.1 8.9 13.9 2.9 7.5 9.6 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Afi1 PF07792.7 CCF49595.1 - 2.5 8.1 14.4 1.7 8.6 8.4 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking zf-C2H2_jaz PF12171.3 CCF49595.1 - 3.2 8.0 10.3 1.9 8.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF4407 PF14362.1 CCF49595.1 - 9.2 5.1 11.1 16 4.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acetyltransf_1 PF00583.19 CCF49597.1 - 0.00061 19.7 0.4 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF49597.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF49597.1 - 0.0054 16.5 0.1 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L39 PF00832.15 CCF49598.1 - 5.9e-22 76.8 10.7 6.8e-22 76.6 7.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.13 CCF49598.1 - 0.46 10.4 3.0 0.48 10.3 2.1 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) adh_short_C2 PF13561.1 CCF49599.1 - 6.8e-31 107.8 0.2 8.2e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCF49599.1 - 1.4e-20 73.8 0.1 2.3e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF49599.1 - 2.8e-09 36.8 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 CCF49599.1 - 0.0027 16.9 0.0 0.0075 15.5 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Polysacc_synt_2 PF02719.10 CCF49599.1 - 0.0063 15.4 0.0 0.0091 14.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ku PF02735.11 CCF49600.1 - 3.9e-26 91.7 0.0 8.4e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCF49600.1 - 2.4e-18 66.4 0.0 7.7e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CCF49600.1 - 2.6e-07 31.0 0.1 6.8e-07 29.7 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 CCF49600.1 - 2.2e-06 27.0 0.0 4.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SAP domain Abhydrolase_3 PF07859.8 CCF49601.1 - 1.6e-27 96.4 0.0 2.1e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF49601.1 - 1.6e-07 31.4 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF49601.1 - 6.9e-07 29.1 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 CCF49601.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 CCF49601.1 - 0.028 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 CCF49601.1 - 0.034 13.8 0.0 0.41 10.3 0.0 2.5 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 CCF49601.1 - 0.11 11.2 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Glyco_transf_90 PF05686.7 CCF49602.1 - 2.6e-16 59.3 0.0 9.2e-16 57.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 RabGAP-TBC PF00566.13 CCF49603.1 - 8.3e-50 169.2 0.0 8.3e-50 169.2 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 CCF49603.1 - 0.0052 16.1 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCF49603.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain zf-C4H2 PF10146.4 CCF49603.1 - 3 7.8 13.3 0.091 12.7 4.0 2.3 2 0 0 2 2 2 0 Zinc finger-containing protein Cyclin_N PF00134.18 CCF49604.1 - 1.2e-08 34.5 0.0 1.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCF49604.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Mannosyl_trans3 PF11051.3 CCF49605.1 - 6.6e-54 183.0 0.1 9.8e-54 182.5 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 CCF49606.1 - 1.7e-46 158.7 0.0 2.6e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative EB PF01683.13 CCF49607.1 - 3e-05 23.9 69.0 0.011 15.8 7.2 6.7 1 1 5 7 7 7 4 EB module Dickkopf_N PF04706.7 CCF49607.1 - 0.035 14.2 69.2 0.2 11.8 2.7 5.7 4 2 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region Rep_fac-A_C PF08646.5 CCF49608.1 - 5.7e-55 185.0 4.4 3.8e-53 179.1 0.3 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 CCF49608.1 - 2.5e-25 88.1 0.6 6.5e-25 86.8 0.4 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 CCF49608.1 - 4.3e-13 48.9 0.2 4e-11 42.6 0.0 3.1 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 CCF49608.1 - 0.00043 20.3 0.3 0.078 13.0 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF3999 PF13163.1 CCF49608.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Pkinase_C PF00433.19 CCF49609.1 - 0.33 11.5 1.7 0.34 11.4 1.1 1.4 1 1 0 1 1 1 0 Protein kinase C terminal domain Nup96 PF12110.3 CCF49610.1 - 7e-97 324.0 0.0 9.5e-97 323.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CCF49610.1 - 3.6e-43 146.7 0.0 1.1e-42 145.2 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCF49610.1 - 4.6e-22 78.3 452.3 4.2e-09 36.6 27.5 12.5 2 2 8 10 10 10 6 Nucleoporin FG repeat region zf-C2H2_jaz PF12171.3 CCF49611.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF49611.1 - 4.1e-05 23.6 0.1 6.7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 CCF49611.1 - 0.00028 20.6 4.7 0.00028 20.6 3.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF3340 PF11818.3 CCF49611.1 - 4.2 7.3 14.2 2.9 7.8 0.5 2.4 1 1 1 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF4355 PF14265.1 CCF49611.1 - 7.2 6.5 17.7 1.4 8.9 8.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) tRNA-synt_1 PF00133.17 CCF49612.1 - 3.8e-227 755.0 0.0 5.9e-227 754.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCF49612.1 - 1.1e-23 83.6 0.0 2.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCF49612.1 - 6.5e-18 64.5 1.7 1.8e-06 26.9 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CCF49612.1 - 0.0016 17.6 0.0 0.0044 16.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Phosducin PF02114.11 CCF49613.1 - 5.1e-19 68.0 1.1 3.7e-08 32.4 0.0 3.1 3 0 0 3 3 3 3 Phosducin Atg14 PF10186.4 CCF49613.1 - 1.3 7.9 4.7 1.8 7.4 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hex_IIIa PF02455.11 CCF49613.1 - 1.7 7.1 9.7 2.4 6.7 6.7 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) GATase_5 PF13507.1 CCF49614.1 - 3.1e-92 308.1 0.0 4.4e-92 307.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCF49614.1 - 1.6e-43 148.3 1.0 1.8e-21 76.7 0.0 2.9 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCF49614.1 - 2.3e-21 75.8 0.2 1.8e-20 73.0 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain zf-CCCH PF00642.19 CCF49615.1 - 3.1e-09 36.3 2.8 6.3e-09 35.3 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 CCF49615.1 - 4.9e-09 36.0 9.7 9e-09 35.2 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF49615.1 - 1.8e-08 33.8 5.3 3e-08 33.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF49615.1 - 1.2e-07 31.3 8.5 1.9e-07 30.6 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCF49615.1 - 1.4e-06 27.9 6.8 2.4e-06 27.2 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCF49615.1 - 2.2e-05 23.9 8.4 4.1e-05 23.1 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCF49615.1 - 0.00022 20.9 6.7 0.00051 19.8 4.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCF49615.1 - 0.00081 19.0 5.4 0.0019 17.9 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 CCF49615.1 - 0.011 15.2 3.7 0.021 14.3 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.13 CCF49615.1 - 0.3 10.2 4.8 1.1 8.4 3.3 1.9 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.2 CCF49615.1 - 0.92 9.6 5.3 3.7 7.7 3.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CCF49615.1 - 0.96 9.2 3.4 1.9 8.3 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein K_oxygenase PF13434.1 CCF49616.1 - 2.1e-81 273.4 0.0 5.8e-79 265.4 0.0 2.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CCF49616.1 - 9.1e-08 32.4 0.0 4.1e-06 27.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF49616.1 - 4.1e-07 29.8 0.3 6.6e-05 22.7 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding AMP-binding PF00501.23 CCF49617.1 - 1.6e-233 774.5 0.0 8.8e-84 281.3 0.0 3.5 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 CCF49617.1 - 2.1e-115 384.7 0.0 4.4e-32 111.1 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 CCF49617.1 - 1.1e-35 121.7 4.1 7.2e-08 32.5 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CCF49617.1 - 2.1e-14 54.1 3.9 1.5e-06 29.0 0.0 4.8 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 CCF49617.1 - 0.043 12.2 0.1 30 2.9 0.0 3.2 3 0 0 3 3 3 0 Transferase family GH3 PF03321.8 CCF49617.1 - 0.43 9.0 0.1 9.1 4.6 0.0 2.9 4 0 0 4 4 4 0 GH3 auxin-responsive promoter DUF3226 PF11536.3 CCF49617.1 - 0.82 9.0 0.0 1.7 7.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) AATase PF07247.7 CCF49617.1 - 4 5.8 0.0 15 3.9 0.0 1.9 3 0 0 3 3 3 0 Alcohol acetyltransferase ANTH PF07651.11 CCF49618.1 - 2.3e-49 167.5 0.0 3.3e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 CCF49618.1 - 2.4e-05 24.3 69.4 0.00049 20.1 15.0 8.1 3 2 2 6 6 6 2 Domain of unknown function (DUF1720) ENTH PF01417.15 CCF49618.1 - 9.8e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Bromodomain PF00439.20 CCF49619.1 - 6.7e-26 90.0 0.0 1.5e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CCF49619.1 - 7.9e-10 38.7 0.2 1.6e-09 37.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF49619.1 - 1.4e-08 34.6 0.1 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1777 PF08648.7 CCF49619.1 - 0.18 11.5 11.2 0.4 10.3 7.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) BC10 PF06726.7 CCF49620.1 - 2.7e-17 62.5 7.0 5.5e-17 61.5 4.8 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 SNF2_N PF00176.18 CCF49621.1 - 3.8e-60 203.2 0.0 5.6e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF49621.1 - 1e-12 47.7 0.0 3e-12 46.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF49621.1 - 2e-06 27.7 0.0 8.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit 2-Hacid_dh_C PF02826.14 CCF49622.1 - 5.4e-47 159.2 0.0 8e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF49622.1 - 7.5e-22 77.2 0.0 1e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCF49622.1 - 0.07 12.9 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase CcmD PF04995.9 CCF49623.1 - 0.16 11.7 2.1 0.28 10.9 1.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pterin_bind PF00809.17 CCF49624.1 - 1.9e-61 207.0 0.3 2.5e-60 203.4 0.1 2.6 2 0 0 2 2 2 1 Pterin binding enzyme FolB PF02152.13 CCF49624.1 - 3.1e-49 165.8 2.8 2.3e-25 88.9 0.5 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 CCF49624.1 - 3.6e-38 130.1 0.0 7.1e-38 129.2 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF1020 PF06255.8 CCF49624.1 - 0.36 9.9 4.5 0.15 11.2 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1020) EST1_DNA_bind PF10373.4 CCF49625.1 - 2.8e-18 66.1 0.0 7.6e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_4 PF13638.1 CCF49625.1 - 7.3e-17 61.7 0.9 3.8e-16 59.3 0.0 2.8 2 1 0 2 2 2 1 PIN domain TPR_11 PF13414.1 CCF49626.1 - 3.5e-28 97.0 13.3 1.1e-13 50.6 0.5 4.9 4 1 1 5 5 4 4 TPR repeat TPR_1 PF00515.23 CCF49626.1 - 5.9e-24 82.6 7.3 0.00015 21.2 0.0 7.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49626.1 - 2.1e-22 79.1 11.1 6e-08 33.1 1.6 5.1 4 1 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCF49626.1 - 2.3e-22 77.0 9.7 0.00016 21.3 0.1 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCF49626.1 - 7.8e-20 70.9 13.6 2.5e-07 30.9 1.8 5.3 4 1 2 6 6 5 5 Tetratricopeptide repeat DnaJ PF00226.26 CCF49626.1 - 4e-19 68.1 0.0 4e-19 68.1 0.0 3.3 4 0 0 4 4 3 1 DnaJ domain TPR_9 PF13371.1 CCF49626.1 - 1.3e-17 63.3 7.3 1.5e-07 31.1 0.5 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCF49626.1 - 3.9e-17 60.6 8.2 0.001 18.6 1.1 7.4 7 1 1 8 8 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF49626.1 - 1.3e-13 50.2 16.1 0.0033 17.9 0.0 7.4 5 3 3 8 8 6 5 Tetratricopeptide repeat Apc3 PF12895.2 CCF49626.1 - 1.4e-10 41.1 13.5 0.00019 21.5 1.8 4.5 5 1 0 5 5 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCF49626.1 - 5.6e-10 38.6 8.2 0.042 14.0 0.2 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCF49626.1 - 9.7e-09 35.1 19.2 0.032 14.6 0.1 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCF49626.1 - 3.3e-08 33.3 16.1 0.0034 17.2 1.3 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCF49626.1 - 8.3e-07 28.3 8.3 0.33 10.8 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCF49626.1 - 1.7e-06 28.0 13.9 0.005 16.9 0.3 5.0 4 1 0 5 5 4 2 Tetratricopeptide repeat NARP1 PF12569.3 CCF49626.1 - 9.1e-06 24.6 13.5 0.0038 16.0 1.1 3.6 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CCF49626.1 - 4.5e-05 22.6 11.9 0.1 11.6 3.3 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCF49626.1 - 6.8e-05 22.6 4.5 0.8 9.6 0.0 5.2 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat YfdX PF10938.3 CCF49626.1 - 0.0022 17.6 16.8 0.12 12.0 0.8 4.4 2 2 1 3 3 3 2 YfdX protein BTAD PF03704.12 CCF49626.1 - 0.0046 17.2 8.1 0.03 14.6 0.1 3.7 3 1 1 4 4 4 2 Bacterial transcriptional activator domain Spectrin PF00435.16 CCF49626.1 - 0.0054 17.0 5.8 0.13 12.5 0.6 4.1 3 2 0 3 3 3 1 Spectrin repeat TPR_21 PF09976.4 CCF49626.1 - 0.0071 16.3 19.5 0.48 10.3 0.9 4.3 4 2 1 6 6 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 CCF49626.1 - 0.018 15.4 8.2 18 6.1 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 CCF49626.1 - 0.047 13.5 6.6 3.3 7.5 0.0 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Med9 PF07544.8 CCF49626.1 - 0.049 13.3 0.7 3.1 7.6 0.0 2.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF1330 PF07045.6 CCF49626.1 - 0.079 12.8 0.4 1.2 9.0 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF1330) DUF4398 PF14346.1 CCF49626.1 - 0.11 12.5 25.1 0.24 11.4 0.3 4.4 4 2 0 4 4 4 0 Domain of unknown function (DUF4398) DUF1759 PF03564.10 CCF49626.1 - 0.13 12.1 2.6 0.11 12.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) SgrR_N PF12793.2 CCF49626.1 - 0.31 11.0 3.0 4.6 7.2 0.1 3.4 3 1 0 3 3 3 0 Sugar transport-related sRNA regulator N-term Apc5 PF12862.2 CCF49626.1 - 0.73 9.7 6.3 0.93 9.3 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.4 CCF49626.1 - 8.4 5.7 8.2 0.27 10.5 0.2 2.6 3 0 0 3 3 3 0 SHNi-TPR DUF3007 PF11460.3 CCF49627.1 - 0.43 10.6 0.1 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DUF2431 PF10354.4 CCF49628.1 - 5.4e-26 91.5 0.0 4.4e-23 82.0 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF2431) Serinc PF03348.10 CCF49629.1 - 8.6e-149 495.8 5.0 1e-148 495.6 3.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YtpI PF14007.1 CCF49629.1 - 2.7 7.9 14.8 0.25 11.2 2.8 3.5 3 0 0 3 3 3 0 YtpI-like protein FA_desaturase PF00487.19 CCF49629.1 - 3.3 7.0 17.7 8.4 5.7 7.2 3.4 2 1 1 3 3 3 0 Fatty acid desaturase EMP70 PF02990.11 CCF49630.1 - 1.6e-177 591.1 0.4 2.4e-177 590.5 0.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Sybindin PF04099.7 CCF49631.1 - 1.5e-08 34.4 0.0 1.7e-06 27.8 0.0 2.3 2 1 0 2 2 2 2 Sybindin-like family GHMP_kinases_N PF00288.21 CCF49632.1 - 8.4e-09 35.3 2.1 2e-08 34.1 1.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCF49632.1 - 0.044 13.9 0.0 0.31 11.2 0.0 2.5 3 0 0 3 3 3 0 GHMP kinases C terminal Brix PF04427.13 CCF49633.1 - 2.9e-44 151.0 0.0 3.9e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain Kelch_3 PF13415.1 CCF49634.1 - 0.11 12.7 1.9 2.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain HSF_DNA-bind PF00447.12 CCF49636.1 - 4.6e-37 126.3 0.1 8.8e-37 125.4 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1465 PF07323.7 CCF49636.1 - 0.0063 16.0 0.5 0.016 14.7 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) GrpE PF01025.14 CCF49636.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 GrpE TFIIA PF03153.8 CCF49637.1 - 8.5e-54 183.8 21.5 4.6e-34 118.9 12.1 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF1958 PF09211.5 CCF49637.1 - 0.076 13.1 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) FLO_LFY PF01698.11 CCF49637.1 - 0.45 9.3 3.1 0.51 9.1 2.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein PWWP PF00855.12 CCF49638.1 - 8.9e-18 64.2 0.0 8.9e-18 64.2 0.0 2.4 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 CCF49638.1 - 0.00063 19.1 0.1 0.0025 17.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF384 PF04064.8 CCF49638.1 - 0.11 12.0 0.6 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Hid1 PF12722.2 CCF49638.1 - 5.1 4.6 11.4 5.8 4.4 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pam17 PF08566.5 CCF49639.1 - 0.09 12.4 0.1 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 BRE1 PF08647.6 CCF49640.1 - 3.6e-20 71.7 10.4 3.6e-20 71.7 7.2 8.3 5 2 5 10 10 9 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.20 CCF49640.1 - 2.1e-06 27.2 11.6 3.6e-06 26.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF49640.1 - 3.6e-06 26.8 11.6 5.7e-06 26.2 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF49640.1 - 9.1e-06 25.3 11.5 1.6e-05 24.4 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCF49640.1 - 4.4e-05 23.0 8.8 7.7e-05 22.2 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CCF49640.1 - 0.00011 21.8 2.7 0.00021 21.0 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CCF49640.1 - 0.0005 19.8 9.6 0.00085 19.0 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain UPF0547 PF10571.4 CCF49640.1 - 0.063 12.9 1.6 0.12 12.1 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-rbx1 PF12678.2 CCF49640.1 - 0.3 11.2 5.1 0.6 10.2 3.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CCF49640.1 - 1.4 8.8 8.1 2.6 7.9 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCF49640.1 - 1.5 8.5 4.5 4.3 7.1 3.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 CCF49640.1 - 3.9 7.3 6.8 8.7 6.2 4.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon RNA_pol_N PF01194.12 CCF49641.1 - 4.5e-30 103.4 0.5 5.2e-30 103.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 CCF49641.1 - 0.08 13.0 0.3 0.12 12.4 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) SecY PF00344.15 CCF49642.1 - 6.9e-97 324.4 8.7 8.6e-97 324.1 6.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCF49642.1 - 3.9e-18 64.6 0.2 1.3e-17 63.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 CCF49642.1 - 0.17 11.6 3.8 1.2 8.7 0.0 3.3 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Ribosomal_L27e PF01777.13 CCF49643.1 - 2.7e-38 129.9 1.6 4.3e-38 129.3 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCF49643.1 - 9.8e-05 21.9 0.7 9.8e-05 21.9 0.5 2.0 2 0 0 2 2 2 1 KOW motif Ribosom_S12_S23 PF00164.20 CCF49644.1 - 8.2e-38 128.5 0.4 9.5e-38 128.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.22 CCF49646.1 - 1.4e-12 47.1 0.1 0.00018 21.1 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp_protease_2 PF13650.1 CCF49647.1 - 3.1e-08 34.0 0.2 5e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCF49647.1 - 3.1e-07 30.4 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 CCF49647.1 - 0.042 13.1 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase MAP65_ASE1 PF03999.7 CCF49648.1 - 0.36 9.3 1.4 0.44 9.0 1.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Metallophos PF00149.23 CCF49650.1 - 5e-39 133.7 0.5 6.4e-39 133.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCF49650.1 - 0.0089 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Rax2 PF12768.2 CCF49651.1 - 5.8e-75 252.1 4.9 2.5e-61 207.3 0.0 5.2 4 1 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 CCF49651.1 - 4.9e-14 51.4 0.0 1.2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF49651.1 - 6.6e-12 44.8 0.1 2.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCF49651.1 - 4.9e-07 29.1 0.0 1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1918 PF08940.6 CCF49651.1 - 0.0069 15.6 0.1 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1918) CcoS PF03597.10 CCF49651.1 - 9.6 5.7 7.7 26 4.3 5.4 1.7 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Tocopherol_cycl PF14249.1 CCF49652.1 - 0.12 11.1 0.1 0.14 10.8 0.1 1.0 1 0 0 1 1 1 0 Tocopherol cyclase YscO PF07321.7 CCF49653.1 - 0.064 13.0 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO HIT PF01230.18 CCF49654.1 - 4.8e-19 68.7 3.6 1e-18 67.6 0.5 2.0 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CCF49654.1 - 2.2e-14 53.6 0.1 3.6e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCF49654.1 - 2.2e-06 27.2 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Peptidase_C80 PF11713.3 CCF49654.1 - 0.0042 16.9 0.4 0.03 14.1 0.0 2.0 1 1 1 2 2 2 1 Peptidase C80 family HBS1_N PF08938.5 CCF49654.1 - 0.078 13.1 0.1 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Rad50_zn_hook PF04423.9 CCF49654.1 - 0.081 12.4 2.7 0.24 10.8 1.9 1.8 1 0 0 1 1 1 0 Rad50 zinc hook motif Metal_resist PF13801.1 CCF49654.1 - 0.086 12.8 0.3 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 Heavy-metal resistance PIG-P PF08510.7 CCF49655.1 - 8.7e-29 99.7 0.8 1.2e-28 99.2 0.6 1.2 1 0 0 1 1 1 1 PIG-P CIA30 PF08547.7 CCF49655.1 - 3e-15 56.4 0.1 5.6e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) DPM2 PF07297.7 CCF49655.1 - 0.12 12.6 2.4 0.22 11.8 1.6 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF3729 PF12526.3 CCF49655.1 - 0.16 13.2 7.8 1.7 9.9 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Baculo_PEP_C PF04513.7 CCF49656.1 - 4.5 7.0 35.6 0.1 12.4 2.6 5.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps53_N PF04100.7 CCF49657.1 - 6.4e-88 295.1 5.5 1e-87 294.4 3.8 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Zw10 PF06248.8 CCF49657.1 - 0.034 12.3 3.9 0.046 11.8 1.7 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 DUF2450 PF10475.4 CCF49657.1 - 0.28 10.0 7.2 0.51 9.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DEAD PF00270.24 CCF49658.1 - 5e-39 133.5 0.0 9e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 CCF49658.1 - 1e-21 76.5 0.3 5.5e-21 74.1 0.3 2.2 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 CCF49658.1 - 5.2e-20 71.0 0.1 1.4e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF49658.1 - 0.00024 20.9 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC4 PF02732.10 CCF49659.1 - 5.4e-14 52.1 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Ribonuclease PF00545.15 CCF49661.1 - 6.6e-14 51.7 0.3 8.2e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 ribonuclease Oxysterol_BP PF01237.13 CCF49663.1 - 1.4e-123 411.9 0.2 7.6e-123 409.4 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank PF00023.25 CCF49663.1 - 1.7e-17 62.2 0.0 0.0001 21.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CCF49663.1 - 1.7e-17 63.5 1.5 3.6e-12 46.4 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCF49663.1 - 1.1e-16 60.4 0.3 0.0003 20.9 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF49663.1 - 4e-13 48.2 0.0 0.021 15.0 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CCF49663.1 - 1.1e-10 41.6 0.6 0.0021 18.5 0.1 4.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) PH_11 PF15413.1 CCF49663.1 - 9.1e-09 35.5 0.1 2.5e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCF49663.1 - 1.7e-08 34.5 0.0 4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 CCF49663.1 - 1.2e-05 25.2 0.1 3.3e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Put_Phosphatase PF06888.7 CCF49664.1 - 3e-50 170.5 0.0 3.4e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 CCF49664.1 - 1.6e-09 38.2 0.0 6.6e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF49664.1 - 0.0053 16.9 0.0 0.0085 16.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RNase_H2-Ydr279 PF09468.5 CCF49665.1 - 5.5 6.1 7.8 7.7 5.6 5.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RhoGEF PF00621.15 CCF49666.1 - 1.5e-18 67.2 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain CBFD_NFYB_HMF PF00808.18 CCF49667.1 - 5.1e-13 48.8 0.3 9.6e-13 47.9 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF49667.1 - 7.9e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Paf1 PF03985.8 CCF49667.1 - 0.00017 20.5 23.9 0.00022 20.1 16.6 1.2 1 0 0 1 1 1 1 Paf1 Nop14 PF04147.7 CCF49667.1 - 0.00072 17.6 30.8 0.00076 17.5 21.3 1.1 1 0 0 1 1 1 1 Nop14-like family VID27 PF08553.5 CCF49667.1 - 0.0032 15.8 16.7 0.0034 15.6 11.6 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein SDA1 PF05285.7 CCF49667.1 - 0.012 14.9 30.7 0.014 14.7 21.3 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.10 CCF49667.1 - 0.016 14.5 20.1 0.017 14.4 13.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF572 PF04502.8 CCF49667.1 - 0.018 14.2 25.2 0.023 13.9 17.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zip PF02535.17 CCF49667.1 - 0.037 13.0 2.5 0.044 12.7 1.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PRP21_like_P PF12230.3 CCF49667.1 - 0.041 13.3 21.0 0.073 12.5 14.6 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein SGT1 PF07093.6 CCF49667.1 - 0.097 11.0 23.6 0.11 10.9 16.3 1.1 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 CCF49667.1 - 0.12 10.8 33.2 0.14 10.5 23.0 1.2 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 CCF49667.1 - 0.35 8.5 17.8 0.39 8.3 12.3 1.2 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CCF49667.1 - 0.88 8.3 14.8 1 8.1 10.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CCF49667.1 - 1.1 9.1 11.8 1.4 8.8 8.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CCF49667.1 - 1.2 8.3 17.8 1.5 8.0 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Astro_capsid PF03115.9 CCF49667.1 - 1.2 7.2 9.3 1.3 7.1 6.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CobT PF06213.7 CCF49667.1 - 2.2 7.3 31.2 3.2 6.8 21.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TP53IP5 PF15331.1 CCF49667.1 - 2.4 8.0 16.0 3.5 7.4 11.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RR_TM4-6 PF06459.7 CCF49667.1 - 3.8 7.3 25.8 5.1 6.9 17.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.1 CCF49667.1 - 4.6 5.2 5.1 4.8 5.2 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.9 CCF49667.1 - 4.7 5.1 29.4 6.3 4.6 20.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 CCF49667.1 - 7.8 5.0 33.8 0.64 8.6 20.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF2890 PF11081.3 CCF49667.1 - 7.9 6.4 33.8 16 5.4 23.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 CCF49667.1 - 9.3 4.4 42.2 14 3.9 29.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pex16 PF08610.5 CCF49667.1 - 9.5 5.1 10.7 41 3.0 5.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DNA_mis_repair PF01119.14 CCF49668.1 - 2.8e-31 107.4 0.0 5.1e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCF49668.1 - 1e-12 47.9 0.0 2.9e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCF49668.1 - 2.6e-10 40.0 0.0 8.8e-10 38.2 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EBP PF05241.7 CCF49669.1 - 5.7e-43 146.1 6.1 1e-42 145.4 4.2 1.3 1 0 0 1 1 1 1 Emopamil binding protein Glycos_transf_1 PF00534.15 CCF49669.1 - 1.1e-11 44.4 0.0 3.8e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCF49669.1 - 0.00078 19.6 0.0 0.0028 17.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCF49669.1 - 0.00095 18.9 0.0 0.0043 16.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DASH_Dam1 PF08653.5 CCF49671.1 - 6.2e-25 86.7 0.3 9.9e-25 86.0 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4557 PF15101.1 CCF49671.1 - 0.0094 15.8 7.2 0.014 15.2 5.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) TrmB PF01978.14 CCF49671.1 - 0.022 14.4 0.0 0.06 13.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_9 PF08221.6 CCF49671.1 - 0.079 12.8 0.1 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain BAF1_ABF1 PF04684.8 CCF49671.1 - 0.13 11.0 15.4 0.21 10.4 10.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.2 CCF49671.1 - 1.6 6.2 8.1 2.1 5.9 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein B12D PF06522.6 CCF49672.1 - 5.2e-06 26.0 0.1 1.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Methyltransf_16 PF10294.4 CCF49673.1 - 6.4e-37 126.6 0.0 2.7e-36 124.6 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Ras PF00071.17 CCF49674.1 - 3.6e-52 176.0 0.0 4.6e-52 175.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF49674.1 - 2.3e-17 63.6 0.0 3.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF49674.1 - 1.8e-12 46.8 0.0 2.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF49674.1 - 0.00014 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF49674.1 - 0.014 14.7 0.0 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CCF49674.1 - 0.078 12.3 0.1 3.7 6.9 0.0 2.1 1 1 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 CCF49674.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SWIRM PF04433.12 CCF49675.1 - 1.7e-15 56.8 0.0 4.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CCF49675.1 - 1.2e-10 41.2 0.0 3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 CCF49675.1 - 1e-08 34.5 6.6 1.9e-08 33.7 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 CCF49675.1 - 2.7e-07 30.5 0.0 8.7e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vfa1 PF08432.5 CCF49675.1 - 9.4 6.2 15.3 5.3 7.0 4.8 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DEAD PF00270.24 CCF49676.1 - 1.6e-45 154.6 0.0 3.1e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF49676.1 - 3.3e-27 94.1 0.0 8.2e-27 92.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF49676.1 - 0.0061 16.4 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3122 PF11320.3 CCF49676.1 - 0.16 11.9 0.0 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3122) zf-HIT PF04438.11 CCF49677.1 - 4e-08 32.7 10.5 6.2e-08 32.1 7.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Pkinase PF00069.20 CCF49678.1 - 8.5e-39 133.2 0.0 1.7e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49678.1 - 1.6e-20 73.2 0.0 2.4e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3844 PF12955.2 CCF49679.1 - 6.3e-29 100.0 1.9 1.1e-28 99.3 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 CCF49679.1 - 0.46 10.6 5.1 0.75 10.0 3.5 1.4 1 0 0 1 1 1 0 EGF-like domain ERO1 PF04137.10 CCF49681.1 - 8.8e-128 426.2 0.0 1.1e-127 425.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF1540 PF07561.6 CCF49681.1 - 0.058 13.4 2.0 0.15 12.0 1.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) CDP-OH_P_transf PF01066.16 CCF49682.1 - 4.2e-16 59.0 7.5 5.5e-16 58.7 4.1 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PPTA PF01239.17 CCF49683.1 - 5.8e-41 136.1 16.4 6.8e-09 34.6 0.1 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_19 PF14559.1 CCF49683.1 - 0.021 15.1 0.0 0.33 11.3 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RNA_pol_Rpb1_7 PF04990.7 CCF49683.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Glyco_hydro_30 PF02055.11 CCF49685.1 - 1.7e-22 79.3 0.3 2.4e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.10 CCF49685.1 - 0.0071 14.4 0.3 0.0095 14.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 AAA_23 PF13476.1 CCF49686.1 - 0.17 12.2 6.7 0.29 11.4 4.7 1.3 1 0 0 1 1 1 0 AAA domain FimP PF09766.4 CCF49686.1 - 0.3 10.1 15.2 0.57 9.1 10.5 1.4 1 0 0 1 1 1 0 Fms-interacting protein DUF775 PF05603.7 CCF49686.1 - 7 6.1 13.4 37 3.7 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Band_3_cyto PF07565.8 CCF49686.1 - 8.9 5.7 11.4 0.44 10.0 2.7 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Muskelin_N PF06588.6 CCF49687.1 - 1.1e-50 172.0 0.3 5.5e-20 71.9 0.0 3.5 3 1 0 3 3 3 3 Muskelin N-terminus Kelch_3 PF13415.1 CCF49687.1 - 1.1e-21 76.3 11.0 3.7e-08 33.3 0.1 7.9 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CCF49687.1 - 1.9e-15 56.3 7.7 0.00011 21.9 0.2 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CCF49687.1 - 2.1e-14 53.0 2.9 0.015 15.2 0.1 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CCF49687.1 - 1.5e-13 50.2 2.4 0.04 14.1 0.0 7.4 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 CCF49687.1 - 1.4e-09 37.2 0.8 0.0025 17.3 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CCF49687.1 - 0.00014 21.5 5.3 0.0089 15.7 0.1 4.8 5 0 0 5 5 5 1 Kelch motif SAP PF02037.22 CCF49688.1 - 5.7e-12 44.8 2.7 2.4e-11 42.8 0.3 2.4 2 0 0 2 2 2 1 SAP domain CAF-1_p150 PF11600.3 CCF49688.1 - 0.00067 19.0 24.5 0.00084 18.7 17.0 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 CCF49688.1 - 0.077 12.2 20.1 0.096 11.8 13.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CCT_2 PF09425.5 CCF49688.1 - 0.17 11.4 0.1 0.17 11.4 0.1 3.1 3 0 0 3 3 3 0 Divergent CCT motif Nucleo_P87 PF07267.6 CCF49688.1 - 0.19 10.3 8.4 0.25 10.0 5.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1180 PF06679.7 CCF49688.1 - 0.99 9.2 9.7 0.22 11.3 4.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1682 PF07946.9 CCF49688.1 - 3.7 6.2 11.3 4.6 5.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.7 CCF49688.1 - 4.8 6.9 18.3 6.9 6.4 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YwiC PF14256.1 CCF49689.1 - 2.1 8.4 7.8 1.8 8.6 2.3 2.7 2 1 1 3 3 3 0 YwiC-like protein SH2 PF00017.19 CCF49690.1 - 0.055 13.2 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 SH2 domain ubiquitin PF00240.18 CCF49691.1 - 5.1e-20 70.6 0.2 5.1e-20 70.6 0.2 1.7 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 CCF49691.1 - 2.5e-19 68.5 6.8 2.7e-11 42.9 0.1 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.6 CCF49691.1 - 2.8e-16 58.6 5.9 2.8e-16 58.6 4.1 2.1 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 CCF49691.1 - 1.8e-08 33.9 0.4 1.8e-08 33.9 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCF49691.1 - 0.019 14.8 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pol_alpha_B_N PF08418.5 CCF49691.1 - 0.24 10.9 12.2 0.15 11.5 2.5 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal FimP PF09766.4 CCF49691.1 - 1.5 7.8 11.9 2.4 7.1 8.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 CCF49691.1 - 1.6 8.8 5.1 0.6 10.1 0.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 CCF49691.1 - 8 6.5 18.4 0.64 10.0 5.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_2 PF00703.16 CCF49692.1 - 0.0033 17.8 0.2 0.28 11.6 0.0 2.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 CCF49692.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain FAD_binding_3 PF01494.14 CCF49693.1 - 7.8e-18 64.6 0.1 4.4e-17 62.1 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCF49693.1 - 5e-05 22.3 0.3 0.0061 15.5 0.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CCF49693.1 - 7.1e-05 21.6 0.0 0.037 12.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 CCF49693.1 - 0.00011 22.1 1.8 0.00028 20.8 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCF49693.1 - 0.0018 18.6 0.3 0.0046 17.3 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF49693.1 - 0.0022 17.7 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 CCF49693.1 - 0.0028 16.5 0.0 1.4 7.7 0.0 2.3 2 1 0 2 2 2 2 Squalene epoxidase FAD_binding_2 PF00890.19 CCF49693.1 - 0.005 15.7 1.6 0.0081 15.0 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCF49693.1 - 0.016 15.1 1.0 0.03 14.2 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCF49693.1 - 0.021 13.9 0.0 0.6 9.1 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 CCF49693.1 - 0.068 11.6 0.7 0.1 11.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCF49693.1 - 0.078 12.7 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PRA1 PF03208.14 CCF49694.1 - 5.5e-39 132.9 0.5 6.4e-39 132.7 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2518 PF10726.4 CCF49694.1 - 1.8 8.0 5.5 0.18 11.3 0.3 1.8 2 0 0 2 2 2 0 Protein of function (DUF2518) PP2C PF00481.16 CCF49695.1 - 3.9e-54 183.7 1.5 5e-54 183.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 CCF49695.1 - 1.3e-50 168.3 71.9 7.5e-08 31.8 0.5 13.4 8 4 6 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF49695.1 - 1.5e-43 146.3 63.2 6e-10 38.7 2.0 8.9 5 2 3 9 9 9 8 Leucine rich repeat Guanylate_cyc PF00211.15 CCF49695.1 - 1.2e-24 86.6 0.0 2.4e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCF49695.1 - 2.2e-20 69.5 73.7 0.073 13.1 0.0 19.6 20 1 0 20 20 20 9 Leucine Rich Repeat RA PF00788.18 CCF49695.1 - 1.3e-09 38.3 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CCF49695.1 - 9.8e-06 24.9 64.4 1.2 9.6 0.0 17.2 19 0 0 19 19 19 5 Leucine rich repeat LRR_6 PF13516.1 CCF49695.1 - 0.0003 20.5 55.3 3.8 7.8 0.1 15.4 17 0 0 17 17 17 3 Leucine Rich repeat LRR_9 PF14580.1 CCF49695.1 - 0.0089 15.6 19.3 0.52 9.8 0.3 5.0 2 1 2 5 5 5 3 Leucine-rich repeat Stc1 PF12898.2 CCF49696.1 - 0.0043 17.0 4.9 0.012 15.6 3.4 1.8 1 0 0 1 1 1 1 Stc1 domain Sporozoite_P67 PF05642.6 CCF49696.1 - 0.054 11.3 1.0 0.077 10.8 0.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytochrome_C554 PF13435.1 CCF49696.1 - 0.15 12.1 3.3 0.46 10.5 0.1 2.9 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Med3 PF11593.3 CCF49696.1 - 2.9 7.0 14.8 5.2 6.1 10.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 CCF49696.1 - 7.5 6.5 16.1 0.48 10.4 7.3 1.9 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein tRNA-synt_2c PF01411.14 CCF49697.1 - 1.3e-210 700.3 0.0 1.9e-210 699.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCF49697.1 - 2.7e-16 59.1 0.2 6e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCF49697.1 - 7e-06 25.6 1.1 2.7e-05 23.7 0.8 2.1 1 0 0 1 1 1 1 DHHA1 domain Ank_2 PF12796.2 CCF49698.1 - 1.2e-12 48.0 0.6 1.3e-07 31.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCF49698.1 - 3.4e-10 39.8 0.6 0.00027 21.0 0.1 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCF49698.1 - 1.2e-09 37.4 0.4 0.00045 19.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCF49698.1 - 3e-06 27.5 1.0 0.0034 17.8 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF49698.1 - 4.7e-06 26.3 0.5 0.029 14.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat DUF1767 PF08585.7 CCF49699.1 - 3.2e-14 52.9 0.0 6.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) SF3b1 PF08920.5 CCF49700.1 - 2.4e-33 115.2 1.5 2.4e-33 115.2 1.1 2.5 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CCF49700.1 - 2.1e-16 59.9 5.7 5.9e-05 23.2 0.0 7.5 7 1 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 CCF49700.1 - 4.1e-10 39.8 4.0 0.23 12.0 0.0 7.9 7 2 2 9 9 9 3 HEAT-like repeat HEAT PF02985.17 CCF49700.1 - 4.8e-09 35.5 7.2 0.39 10.9 0.0 9.3 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 CCF49700.1 - 9.7e-08 30.7 2.7 0.088 11.1 0.1 4.1 1 1 1 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CCF49700.1 - 5.6e-07 29.8 0.8 1.5 9.2 0.0 5.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCF49700.1 - 0.00013 21.3 2.6 0.2 10.9 0.0 4.2 4 1 0 4 4 4 1 CLASP N terminal MMS19_N PF14500.1 CCF49700.1 - 0.0012 18.2 0.8 6.4 5.9 0.1 4.0 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Dopey_N PF04118.9 CCF49700.1 - 0.012 14.4 0.8 0.12 11.1 0.0 2.9 3 1 0 4 4 4 0 Dopey, N-terminal MMS19_C PF12460.3 CCF49700.1 - 0.029 13.1 0.0 6.3 5.3 0.1 3.6 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal MOZ_SAS PF01853.13 CCF49701.1 - 4.6e-85 283.6 0.9 7.2e-85 282.9 0.6 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CCF49701.1 - 6.3e-24 83.4 0.0 1.3e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-C2H2 PF00096.21 CCF49701.1 - 0.064 13.6 2.3 0.17 12.2 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type TCTP PF00838.12 CCF49703.1 - 0.079 12.9 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 Translationally controlled tumour protein Apc5 PF12862.2 CCF49704.1 - 0.12 12.2 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF1814 PF08843.6 CCF49705.1 - 0.034 13.9 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) SIR2 PF02146.12 CCF49707.1 - 4.7e-30 104.6 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 2 Sir2 family Na_Ca_ex PF01699.19 CCF49708.1 - 3.5e-28 97.9 13.9 3.3e-16 59.1 0.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1686 PF07937.6 CCF49708.1 - 0.00018 21.1 0.4 0.00039 20.1 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1686) Spore_permease PF03845.8 CCF49708.1 - 0.12 10.9 6.9 0.061 11.9 1.0 2.2 2 0 0 2 2 2 0 Spore germination protein FUSC_2 PF13515.1 CCF49708.1 - 4.9 7.0 14.1 0.09 12.7 1.6 3.1 3 0 0 3 3 3 0 Fusaric acid resistance protein-like Ribosomal_S8e PF01201.17 CCF49710.1 - 3e-36 124.4 7.7 4.6e-35 120.6 5.3 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 CCF49710.1 - 0.015 15.2 3.3 0.019 14.8 1.1 1.8 1 1 1 2 2 2 0 Mer2 AAA_13 PF13166.1 CCF49710.1 - 1.7 6.9 6.2 2.1 6.6 4.3 1.0 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 CCF49710.1 - 8.2 4.5 10.9 11 4.1 7.6 1.0 1 0 0 1 1 1 0 Transmembrane protein ABC2_membrane PF01061.19 CCF49711.1 - 1.8e-70 236.4 47.8 9e-40 136.0 13.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCF49711.1 - 2.6e-36 124.9 0.0 2.3e-17 63.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCF49711.1 - 1.4e-19 69.6 3.4 2.6e-17 62.3 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_25 PF13481.1 CCF49711.1 - 7e-07 28.8 0.3 0.00035 20.0 0.1 2.6 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 CCF49711.1 - 5.4e-05 23.3 0.2 0.1 12.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCF49711.1 - 8.2e-05 22.0 2.6 0.015 14.7 0.4 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF49711.1 - 0.00038 20.6 1.1 1.3 9.1 0.3 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCF49711.1 - 0.00067 19.9 0.4 0.13 12.5 0.1 3.0 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCF49711.1 - 0.0014 17.8 0.2 0.0086 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCF49711.1 - 0.0056 17.4 0.1 0.12 13.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 CCF49711.1 - 0.017 15.0 0.6 7.2 6.5 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.14 CCF49711.1 - 0.032 13.4 0.1 2 7.6 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCF49711.1 - 0.06 13.6 0.3 0.41 10.9 0.2 2.2 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 CCF49711.1 - 0.061 13.2 4.1 0.059 13.3 1.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCF49711.1 - 0.1 12.2 1.9 0.3 10.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CCF49711.1 - 0.11 12.4 8.7 1.5 8.7 2.8 3.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 CCF49711.1 - 0.15 11.5 1.3 6.9 6.0 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 CCF49711.1 - 0.15 11.7 0.6 3.9 7.1 0.3 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 CCF49711.1 - 0.15 11.4 2.7 0.51 9.7 0.6 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCF49711.1 - 0.23 10.9 0.3 0.63 9.5 0.2 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCF49711.1 - 0.23 11.6 0.3 66 3.7 0.2 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCF49711.1 - 0.44 10.3 3.8 17 5.2 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain KaiC PF06745.8 CCF49711.1 - 0.64 9.0 1.7 1.9 7.5 0.3 2.3 3 0 0 3 3 3 0 KaiC ABC_ATPase PF09818.4 CCF49711.1 - 0.68 8.4 1.8 0.76 8.2 0.5 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 CCF49711.1 - 1.7 8.0 9.1 0.52 9.7 0.1 2.9 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 CCF49711.1 - 8.2 5.9 7.5 4 6.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain adh_short PF00106.20 CCF49713.1 - 7.9e-25 87.6 1.2 1e-24 87.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF49713.1 - 2.1e-24 86.5 0.3 2.7e-24 86.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF49713.1 - 5.1e-11 42.5 0.4 7.1e-11 42.0 0.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCF49713.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SBP_bac_11 PF13531.1 CCF49713.1 - 0.057 13.0 0.6 0.094 12.3 0.4 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein S4 PF01479.20 CCF49713.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 S4 domain ox_reductase_C PF08635.5 CCF49714.1 - 5.8e-52 174.9 0.0 1.1e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CCF49714.1 - 1.7e-12 47.9 0.0 2.8e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCF49714.1 - 1.3e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain XPG_I PF00867.13 CCF49714.1 - 0.089 12.8 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 XPG I-region NAD_binding_10 PF13460.1 CCF49715.1 - 2.1e-06 27.8 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Dabb PF07876.7 CCF49716.1 - 4.2e-18 65.5 0.5 4.7e-18 65.4 0.3 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain L_protein_N PF15518.1 CCF49716.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.5 1 1 0 1 1 1 0 L protein N-terminus ADIP PF11559.3 CCF49717.1 - 8.6e-26 90.6 7.5 8.6e-26 90.6 5.2 5.8 5 1 1 6 6 6 1 Afadin- and alpha -actinin-Binding Histone PF00125.19 CCF49718.1 - 7.5e-28 96.4 0.0 1.3e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nup35_RRM PF05172.8 CCF49719.1 - 1.4e-07 31.1 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCF49719.1 - 0.00038 20.1 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4638 PF15472.1 CCF49719.1 - 0.52 9.8 1.7 1 8.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) IncA PF04156.9 CCF49719.1 - 1.9 8.0 9.0 3.8 7.0 6.2 1.4 1 0 0 1 1 1 0 IncA protein DAO PF01266.19 CCF49720.1 - 3.9e-49 167.4 0.2 4.5e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCF49720.1 - 1.2e-06 28.7 0.3 0.00056 20.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF49720.1 - 4.9e-06 26.5 1.0 0.00023 21.0 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 CCF49720.1 - 0.0004 18.6 0.1 0.34 9.0 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 CCF49720.1 - 0.0011 18.9 0.5 0.0024 17.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCF49720.1 - 0.0034 16.0 0.5 0.0052 15.4 0.4 1.2 1 0 0 1 1 1 1 Tryptophan halogenase K_oxygenase PF13434.1 CCF49720.1 - 0.017 14.0 0.2 0.31 9.9 0.1 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.14 CCF49720.1 - 0.032 13.3 0.1 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Saccharop_dh PF03435.13 CCF49720.1 - 0.048 12.6 0.1 0.075 12.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 CCF49720.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 CCF49720.1 - 0.064 12.6 0.6 0.18 11.2 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 CCF49720.1 - 0.077 12.7 0.3 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCF49720.1 - 0.092 11.6 0.3 0.15 10.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 CCF49720.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 CCF49720.1 - 0.13 11.1 5.3 0.61 8.8 3.6 1.9 1 1 0 1 1 1 0 FAD binding domain Sugar_tr PF00083.19 CCF49721.1 - 1.7e-18 66.4 23.5 2.2e-16 59.4 16.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4199 PF13858.1 CCF49721.1 - 0.055 13.3 12.7 1.4 8.7 3.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) RA PF00788.18 CCF49723.1 - 2.1e-18 66.5 0.1 3.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 CCF49723.1 - 7.7e-14 51.2 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCF49723.1 - 1.3e-13 50.8 0.1 2.6e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CCF49723.1 - 5e-13 48.2 0.4 1.4e-07 30.7 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCF49723.1 - 1.2e-10 40.7 2.5 1.4e-05 24.5 0.1 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 CCF49723.1 - 9.7e-10 37.7 0.8 2.2e-06 27.0 0.0 2.9 2 1 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CCF49723.1 - 0.0035 17.5 6.8 0.049 13.8 0.0 3.9 4 1 0 4 4 4 1 Bacterial SH3 domain DUF4219 PF13961.1 CCF49724.1 - 0.22 10.9 1.7 0.35 10.3 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) rve PF00665.21 CCF49725.1 - 5e-10 39.5 0.8 5e-07 29.8 0.1 2.2 1 1 1 2 2 2 2 Integrase core domain rve_3 PF13683.1 CCF49725.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Prim_Zn_Ribbon PF08273.7 CCF49727.1 - 5.5e-05 23.1 0.7 0.00011 22.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding domain of primase-helicase TF_Zn_Ribbon PF08271.7 CCF49727.1 - 6.5e-05 22.1 0.4 0.00012 21.3 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 CCF49727.1 - 0.002 17.2 0.4 0.0037 16.4 0.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain A2L_zn_ribbon PF08792.5 CCF49727.1 - 0.088 12.2 0.8 5.1 6.6 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain ADH_N PF08240.7 CCF49728.1 - 2.5e-13 49.7 0.3 4.2e-13 48.9 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 CCF49728.1 - 1.3e-07 31.1 0.0 1.3e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 CCF49728.1 - 3.7e-05 23.2 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase SurE PF01975.12 CCF49730.1 - 3.6e-43 147.1 0.0 5.5e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Cation_ATPase_C PF00689.16 CCF49731.1 - 5.3e-05 22.8 3.4 7.6e-05 22.3 2.4 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Herpes_glycop PF01528.11 CCF49731.1 - 0.062 11.9 5.4 0.1 11.2 3.8 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3273 PF11677.3 CCF49731.1 - 0.15 11.2 5.9 0.13 11.5 2.4 1.9 1 1 1 3 3 3 0 Protein of unknown function (DUF3273) E1-E2_ATPase PF00122.15 CCF49732.1 - 1.7e-30 105.8 0.0 2.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 CCF49732.1 - 1.2e-25 89.7 0.0 2.9e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 CCF49732.1 - 1.1e-23 84.4 0.0 2.3e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF49732.1 - 1.3e-22 81.2 0.0 2.8e-21 76.9 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF49732.1 - 3.9e-06 26.2 0.0 7.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCF49732.1 - 1.5e-05 24.8 0.1 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF49732.1 - 0.014 14.9 0.1 0.34 10.4 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TFIIA PF03153.8 CCF49732.1 - 0.96 9.2 8.3 1.9 8.3 5.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1349 PF07081.6 CCF49733.1 - 1.4e-16 60.3 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF2514 PF10721.4 CCF49734.1 - 0.13 12.0 1.0 0.15 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) AA_permease PF00324.16 CCF49735.1 - 9.4e-95 317.7 47.5 1.2e-94 317.4 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF49735.1 - 7.1e-26 90.7 51.9 8.5e-26 90.4 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3169 PF11368.3 CCF49735.1 - 0.048 12.8 0.0 0.048 12.8 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) DUF1308 PF07000.6 CCF49735.1 - 0.27 9.8 0.6 0.38 9.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) SLAC1 PF03595.12 CCF49736.1 - 1.7e-81 273.4 57.1 1.9e-81 273.2 39.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MFS_1 PF07690.11 CCF49737.1 - 1.6e-24 86.2 33.2 1.6e-18 66.6 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DPPIV_N PF00930.16 CCF49738.1 - 7.2e-75 251.7 0.0 1.4e-74 250.8 0.0 1.5 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCF49738.1 - 1.9e-45 154.6 1.4 3.1e-45 154.0 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCF49738.1 - 2.5e-09 37.3 0.5 1.9e-07 31.2 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF49738.1 - 6e-09 35.7 0.1 1.7e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CCF49738.1 - 0.00012 21.6 1.7 0.00058 19.3 0.6 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 CCF49738.1 - 0.0003 20.5 0.0 0.63 9.7 0.0 2.3 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 CCF49738.1 - 0.11 11.0 0.0 5.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3830 PF12903.2 CCF49738.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) zf-CCHC PF00098.18 CCF49739.1 - 0.014 15.2 1.3 0.027 14.4 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCF49739.1 - 0.044 13.4 0.1 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.1 CCF49739.1 - 0.094 12.1 0.5 0.82 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) rve PF00665.21 CCF49740.1 - 3.2e-20 72.4 0.1 4.9e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF49740.1 - 1.5e-07 30.9 0.2 2.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CCF49740.1 - 0.046 13.2 0.1 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 CCF49741.1 - 3.4e-43 147.4 0.0 1.9e-37 128.5 0.0 2.1 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) HSF_DNA-bind PF00447.12 CCF49742.1 - 8e-34 115.9 0.1 1.3e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TPR_MLP1_2 PF07926.7 CCF49742.1 - 0.12 12.1 0.5 0.24 11.1 0.3 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BCDHK_Adom3 PF10436.4 CCF49743.1 - 1.4e-66 223.0 0.0 2.9e-66 222.0 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCF49743.1 - 2.5e-19 69.0 0.0 6.4e-19 67.7 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCF49743.1 - 3.5e-06 26.6 0.0 7.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IFT57 PF10498.4 CCF49743.1 - 0.11 11.1 0.1 0.23 10.1 0.1 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Mt_ATP-synt_B PF05405.9 CCF49746.1 - 7.5e-45 152.3 8.5 8.8e-45 152.0 5.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2704 PF10866.3 CCF49746.1 - 0.023 14.1 0.4 0.08 12.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2704) Viral_Hsp90 PF03225.9 CCF49746.1 - 0.038 12.2 0.1 0.053 11.7 0.1 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Cauli_DNA-bind PF03310.8 CCF49746.1 - 0.47 10.3 4.3 0.22 11.3 1.2 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein PBP_sp32 PF07222.7 CCF49746.1 - 0.5 9.4 4.6 0.71 9.0 3.2 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ank_4 PF13637.1 CCF49747.1 - 8.7e-17 61.1 1.5 4.5e-12 46.1 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCF49747.1 - 1.1e-16 60.9 0.2 8.5e-14 51.6 0.3 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCF49747.1 - 1.1e-14 53.3 0.8 1.4e-05 24.5 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCF49747.1 - 2.2e-12 45.9 0.2 0.00093 19.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CCF49747.1 - 4.2e-12 45.8 1.0 8.5e-05 22.6 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Nop53 PF07767.6 CCF49748.1 - 4.5e-81 272.8 24.8 6.2e-81 272.3 17.2 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3658 PF12395.3 CCF49748.1 - 0.023 14.2 1.0 1.3 8.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function CDC45 PF02724.9 CCF49748.1 - 0.43 8.5 10.8 0.61 8.0 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Ssl1 PF04056.9 CCF49750.1 - 4.8e-69 231.8 0.0 7e-69 231.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CCF49750.1 - 4.3e-16 58.6 9.3 4.3e-16 58.6 6.5 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CCF49750.1 - 5.1e-11 42.9 0.0 9.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 CCF49750.1 - 0.15 11.4 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 CCF49750.1 - 0.16 11.7 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain Snf7 PF03357.16 CCF49751.1 - 1.8e-49 167.4 16.7 2.2e-49 167.1 11.6 1.0 1 0 0 1 1 1 1 Snf7 NuA4 PF09340.5 CCF49751.1 - 0.0012 18.4 1.1 0.003 17.1 0.8 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Mod_r PF07200.8 CCF49751.1 - 0.0024 17.8 12.2 0.0026 17.6 5.5 2.0 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Soyouz_module PF14313.1 CCF49751.1 - 0.014 14.9 1.1 4.9 6.7 0.0 3.3 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PglZ PF08665.7 CCF49751.1 - 0.051 13.2 3.2 9.6 5.8 0.0 2.6 2 1 1 3 3 3 0 PglZ domain Prefoldin PF02996.12 CCF49751.1 - 0.096 12.3 11.4 6 6.5 0.1 3.5 4 0 0 4 4 4 0 Prefoldin subunit Hemerythrin PF01814.18 CCF49751.1 - 0.13 12.4 3.1 0.39 10.8 2.0 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF848 PF05852.6 CCF49751.1 - 0.19 11.5 9.7 0.3 10.9 5.1 2.2 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) ATP-synt_ab_C PF00306.22 CCF49751.1 - 0.29 11.6 8.0 0.32 11.4 4.6 1.7 2 0 0 2 2 1 0 ATP synthase alpha/beta chain, C terminal domain Prefoldin_2 PF01920.15 CCF49751.1 - 0.49 10.1 17.3 1 9.1 0.0 3.4 2 1 0 2 2 2 0 Prefoldin subunit Nup54 PF13874.1 CCF49751.1 - 0.74 9.4 9.8 4.4 6.9 5.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Mnd1 PF03962.10 CCF49751.1 - 1.1 8.9 16.5 2.5 7.7 9.5 2.3 2 1 0 2 2 2 0 Mnd1 family FlxA PF14282.1 CCF49751.1 - 1.1 9.2 11.0 1.7 8.6 5.1 2.4 1 1 1 2 2 2 0 FlxA-like protein EMP24_GP25L PF01105.19 CCF49751.1 - 1.5 8.4 6.5 5.3 6.7 0.0 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Phage_GP20 PF06810.6 CCF49751.1 - 1.6 8.1 16.6 9.3 5.6 9.1 2.8 2 1 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.6 CCF49751.1 - 2.6 8.0 6.0 15 5.5 0.0 3.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 CCF49751.1 - 3.1 8.1 7.2 3.3 8.0 0.7 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 CCF49751.1 - 4.1 5.1 9.0 6.7 4.4 6.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family BAR PF03114.13 CCF49752.1 - 1.9e-47 161.6 1.0 2.3e-47 161.4 0.7 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 CCF49752.1 - 0.0017 17.7 2.0 0.0035 16.7 1.4 1.8 1 1 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.1 CCF49752.1 - 0.0046 15.4 2.4 0.0058 15.1 1.7 1.2 1 0 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 CCF49752.1 - 0.026 12.2 4.5 0.044 11.5 3.1 1.4 1 1 0 1 1 1 0 Myosin tail GAS PF13851.1 CCF49752.1 - 0.03 13.5 1.5 0.64 9.1 0.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec2p PF06428.6 CCF49752.1 - 0.041 13.7 4.5 0.67 9.8 0.4 3.3 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p HHH_8 PF14716.1 CCF49752.1 - 0.053 13.7 2.8 8.3 6.6 0.1 2.7 1 1 1 2 2 2 0 Helix-hairpin-helix domain HD_3 PF13023.1 CCF49752.1 - 0.064 12.9 0.8 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 HD domain TMPIT PF07851.8 CCF49752.1 - 0.1 11.6 1.5 0.38 9.7 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Vps5 PF09325.5 CCF49752.1 - 0.18 11.0 3.8 3 7.0 2.6 2.2 1 1 0 1 1 1 0 Vps5 C terminal like Sigma70_ner PF04546.8 CCF49752.1 - 0.36 10.4 5.6 0.76 9.3 1.8 2.6 1 1 2 3 3 3 0 Sigma-70, non-essential region Laminin_I PF06008.9 CCF49752.1 - 1.6 7.9 9.1 0.11 11.7 0.5 2.3 3 0 0 3 3 3 0 Laminin Domain I Metallophos PF00149.23 CCF49754.1 - 7.6e-28 97.2 0.0 4.3e-27 94.8 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCF49754.1 - 1.7e-19 69.1 3.8 4.2e-14 51.9 0.5 2.5 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 CCF49754.1 - 2e-12 46.9 0.0 4.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 CCF49754.1 - 7.1e-11 41.2 4.8 0.0002 20.8 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF49754.1 - 2.3e-07 30.2 4.9 0.084 12.8 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49754.1 - 7.8e-05 23.2 1.2 0.00069 20.2 0.2 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCF49754.1 - 0.0082 16.2 0.1 2.9 8.2 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat VitD-bind_III PF09164.5 CCF49754.1 - 0.12 12.0 0.3 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III TPR_8 PF13181.1 CCF49754.1 - 0.14 12.0 0.0 35 4.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HAD_2 PF13419.1 CCF49755.1 - 4.4e-16 59.5 0.0 2.3e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF49755.1 - 2e-08 34.9 0.0 7.9e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF49755.1 - 0.002 17.8 0.0 0.014 15.1 0.0 2.3 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CCF49755.1 - 0.057 13.3 0.0 12 5.8 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF49755.1 - 0.084 13.0 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HRM PF02793.17 CCF49755.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Hormone receptor domain Vps5 PF09325.5 CCF49756.1 - 6.5e-66 221.9 4.2 6.5e-66 221.9 2.9 2.2 2 0 0 2 2 2 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 CCF49756.1 - 1.7e-49 168.2 0.0 3.9e-49 167.0 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 CCF49756.1 - 2.3e-24 86.1 0.0 4.3e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.19 CCF49756.1 - 1.2e-22 79.8 0.0 2.9e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 PX domain NAD_binding_10 PF13460.1 CCF49756.1 - 4e-09 36.7 0.0 9.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCF49756.1 - 3.8e-08 32.5 0.1 1.2e-06 27.6 0.1 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 CCF49756.1 - 0.00013 21.0 0.0 0.0021 17.0 0.0 2.5 1 1 1 2 2 2 1 Male sterility protein SAD_SRA PF02182.12 CCF49757.1 - 2e-42 144.1 0.0 3.4e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Peptidase_S9_N PF02897.10 CCF49758.1 - 4.4e-87 292.3 3.6 5.5e-87 292.0 2.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CCF49758.1 - 8.4e-51 172.2 0.1 1.3e-50 171.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase PF00069.20 CCF49759.1 - 1.1e-70 237.8 0.0 1.2e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49759.1 - 5e-31 107.6 0.0 6.2e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF49759.1 - 2.9e-05 23.1 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF49759.1 - 0.003 17.3 0.0 0.0082 15.8 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCF49759.1 - 0.0054 15.6 0.0 0.0083 15.0 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Glyco_hydro_18 PF00704.23 CCF49760.1 - 1.2e-06 28.2 0.4 4.6e-05 23.0 0.3 3.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Moulting_cycle PF04870.11 CCF49760.1 - 0.029 13.4 3.7 0.048 12.7 2.6 1.2 1 0 0 1 1 1 0 Moulting cycle SprA-related PF12118.3 CCF49760.1 - 0.033 13.5 6.9 0.05 12.9 4.8 1.2 1 0 0 1 1 1 0 SprA-related family zf-CCHC PF00098.18 CCF49761.1 - 0.00019 21.1 0.6 0.00044 20.0 0.4 1.7 1 0 0 1 1 1 1 Zinc knuckle 2_5_RNA_ligase2 PF13563.1 CCF49761.1 - 0.011 15.4 0.1 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily zf-CCHC_6 PF15288.1 CCF49761.1 - 0.014 15.0 0.5 0.035 13.7 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle HypA PF01155.14 CCF49761.1 - 0.069 12.8 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family MTP18 PF10558.4 CCF49762.1 - 1.4e-59 200.2 0.1 2.4e-59 199.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Pep3_Vps18 PF05131.9 CCF49763.1 - 2.8e-41 140.3 0.0 5.2e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCF49763.1 - 1.2e-10 41.1 1.3 1.9e-05 24.3 0.0 3.3 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CCF49763.1 - 0.001 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CCF49763.1 - 0.012 15.4 5.7 0.017 14.9 2.3 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CCF49763.1 - 0.2 11.4 8.3 0.012 15.2 1.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain TPR_11 PF13414.1 CCF49763.1 - 0.2 11.3 1.7 3.9 7.1 0.0 3.3 4 0 0 4 4 4 0 TPR repeat zf-C3HC4_2 PF13923.1 CCF49763.1 - 0.39 10.7 4.9 0.28 11.2 1.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF49763.1 - 1.3 8.7 4.3 1.2 8.8 1.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L2 PF00181.18 CCF49766.1 - 0.0043 17.0 0.0 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain RNase_H PF00075.19 CCF49769.1 - 0.036 14.4 0.4 0.062 13.6 0.1 1.5 2 0 0 2 2 2 0 RNase H Med24_N PF11277.3 CCF49769.1 - 0.098 10.1 0.0 0.12 9.9 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal rve PF00665.21 CCF49770.1 - 1.6e-14 54.0 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF49770.1 - 1e-06 27.9 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CCF49771.1 - 8e-07 28.7 1.0 3.1e-06 26.8 0.7 2.1 1 0 0 1 1 1 1 Zinc knuckle Ipi1_N PF12333.3 CCF49772.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation HTH_37 PF13744.1 CCF49773.1 - 0.017 14.9 4.8 0.02 14.7 2.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain ACR_tran PF00873.14 CCF49773.1 - 0.027 11.8 1.1 0.035 11.5 0.8 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Aminotran_3 PF00202.16 CCF49773.1 - 0.061 12.1 1.1 0.073 11.9 0.8 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Penaeidin PF05927.6 CCF49774.1 - 0.016 15.7 0.0 0.07 13.6 0.0 2.1 1 1 1 2 2 2 0 Penaeidin T_cell_tran_alt PF15128.1 CCF49774.1 - 0.1 12.0 0.3 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Herpes_BLLF1 PF05109.8 CCF49776.1 - 0.15 9.9 17.3 0.18 9.7 12.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) KAR9 PF08580.5 CCF49776.1 - 0.84 7.8 7.1 0.91 7.7 4.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF566 PF04484.7 CCF49776.1 - 1.8 7.9 7.9 2.2 7.6 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DDE_3 PF13358.1 CCF49779.1 - 1.3e-15 57.3 0.0 2.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CCF49779.1 - 9.7e-10 38.3 3.9 1.7e-09 37.5 1.9 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 CCF49779.1 - 0.00092 18.7 0.0 0.0036 16.9 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 CCF49779.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.7 1 1 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.1 CCF49779.1 - 0.042 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 CCF49779.1 - 0.095 12.0 0.1 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DDE_3 PF13358.1 CCF49781.1 - 9.9e-16 57.8 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CCF49781.1 - 2.9e-10 40.0 2.7 5.6e-10 39.1 1.2 2.0 2 0 0 2 2 2 1 Transposase STT3 PF02516.9 CCF49782.1 - 2.6e-129 432.3 35.8 9.3e-124 414.0 22.8 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RVT_1 PF00078.22 CCF49783.1 - 5.8e-25 87.9 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49783.1 - 3.2e-20 72.4 0.0 6.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49783.1 - 5.4e-13 48.3 1.0 2.1e-12 46.5 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CCF49783.1 - 0.11 12.0 1.4 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain Lectin_C PF00059.16 CCF49785.1 - 0.14 12.8 1.4 0.72 10.5 0.1 2.2 1 1 1 2 2 2 0 Lectin C-type domain NPV_P10 PF05531.7 CCF49786.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RVT_2 PF07727.9 CCF49788.1 - 2.7e-59 200.1 0.1 6.6e-59 198.8 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49788.1 - 7.1e-15 55.1 0.0 1.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CCF49788.1 - 5.5e-05 22.8 2.4 0.00012 21.8 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF3858 PF12970.2 CCF49788.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) RVT_1 PF00078.22 CCF49792.1 - 5.4e-23 81.4 0.0 1e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49792.1 - 4.1e-20 72.0 0.0 9.9e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49792.1 - 1.4e-11 43.9 1.2 3.4e-11 42.6 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 CCF49792.1 - 1.9e-05 24.3 2.5 5.3e-05 22.9 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CCF49792.1 - 0.0043 17.0 1.1 0.012 15.6 0.1 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CCF49792.1 - 0.0058 16.1 0.3 0.018 14.5 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Tubulin PF00091.20 CCF49796.1 - 3.6e-64 216.5 0.0 5.4e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCF49796.1 - 3.2e-41 140.3 0.0 4.6e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCF49796.1 - 0.0015 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCF49796.1 - 0.0024 17.8 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain RecT PF03837.9 CCF49796.1 - 0.092 12.0 0.3 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 RecT family Tubulin_2 PF13809.1 CCF49796.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like MS_channel PF00924.13 CCF49797.1 - 5.7e-19 68.2 1.4 9.6e-19 67.5 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CCF49797.1 - 1.7e-05 23.7 0.1 3.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CCF49797.1 - 0.00016 21.2 0.0 0.00041 19.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CCF49797.1 - 0.00018 20.6 0.3 0.00047 19.3 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CCF49797.1 - 0.00055 20.0 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CCF49797.1 - 0.00097 18.7 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair PBP1_TM PF14812.1 CCF49797.1 - 0.044 14.1 1.0 0.17 12.2 0.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.17 CCF49797.1 - 1.5 7.7 12.0 0.014 14.3 0.9 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter SRF-TF PF00319.13 CCF49798.1 - 2.3e-22 77.9 0.1 6.2e-22 76.5 0.0 1.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BNR PF02012.15 CCF49799.1 - 1.6e-05 24.0 45.1 2 8.6 0.5 11.8 11 0 0 11 11 11 6 BNR/Asp-box repeat Fe_dep_repr_C PF02742.10 CCF49799.1 - 0.0017 17.9 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain DUF4449 PF14613.1 CCF49801.1 - 6.1e-24 84.8 5.2 1.3e-14 54.4 0.8 4.0 2 2 3 5 5 5 2 Protein of unknown function (DUF4449) Sec7 PF01369.15 CCF49802.1 - 1.3e-33 116.3 0.0 2.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain SET PF00856.23 CCF49803.1 - 2.8e-21 76.5 0.1 1.6e-20 74.0 0.1 2.2 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 CCF49803.1 - 1.4e-13 50.9 1.1 1.4e-13 50.9 0.8 2.1 2 1 0 2 2 2 1 Pre-SET motif NAD_binding_8 PF13450.1 CCF49804.1 - 4.9e-10 39.2 0.0 1.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCF49804.1 - 0.00074 19.4 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF49804.1 - 0.0023 17.0 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CCF49804.1 - 0.0052 15.3 0.1 0.031 12.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CCF49804.1 - 0.0054 15.6 0.2 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF3386 PF11866.3 CCF49804.1 - 0.0055 15.9 0.3 0.0099 15.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3386) Pyr_redox_3 PF13738.1 CCF49804.1 - 0.0092 16.0 0.0 0.087 12.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF49804.1 - 0.1 13.0 0.1 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF49804.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 CCF49804.1 - 0.18 11.5 0.6 0.67 9.7 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FMO-like PF00743.14 CCF49805.1 - 8.6e-33 113.3 0.0 4.5e-11 41.6 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCF49805.1 - 4.8e-19 69.2 0.0 2.2e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF49805.1 - 4.2e-07 29.8 0.0 5e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CCF49805.1 - 4.4e-07 29.8 0.0 2.3e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCF49805.1 - 6.1e-07 29.5 0.0 0.0042 16.9 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF49805.1 - 1.2e-06 27.6 0.2 0.021 13.7 0.0 3.9 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 CCF49805.1 - 0.0011 19.1 0.2 0.026 14.6 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCF49805.1 - 0.0013 19.1 0.1 0.53 10.7 0.1 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF49805.1 - 0.011 14.8 0.0 5.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 CCF49805.1 - 0.025 13.5 0.0 1.8 7.4 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCF49805.1 - 0.12 12.6 0.0 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 CCF49805.1 - 0.12 12.7 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SYS1 PF09801.4 CCF49807.1 - 1.8e-22 79.8 6.4 2.4e-17 63.2 2.4 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network zf-RING_2 PF13639.1 CCF49808.1 - 3.2e-13 49.2 1.7 5.3e-13 48.5 1.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCF49808.1 - 3.7e-08 32.8 0.6 6.8e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF49808.1 - 1.5e-07 31.3 1.4 3.1e-07 30.3 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF49808.1 - 6.2e-07 29.0 0.9 1.1e-06 28.2 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCF49808.1 - 7.1e-07 28.8 0.0 2.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCF49808.1 - 5.5e-05 22.7 0.7 0.0001 21.8 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF49808.1 - 0.00019 21.4 1.5 0.00046 20.2 1.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCF49808.1 - 0.00088 19.1 1.2 0.0018 18.2 0.9 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 CCF49808.1 - 0.026 14.3 1.0 0.096 12.5 0.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CCF49808.1 - 0.057 13.4 1.7 0.14 12.2 1.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-Apc11 PF12861.2 CCF49808.1 - 0.18 11.6 0.4 0.39 10.5 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribonuc_P_40 PF08584.6 CCF49809.1 - 9.8e-25 87.1 0.0 2.9e-17 62.5 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit SHS2_Rpb7-N PF03876.12 CCF49810.1 - 1.3e-13 50.8 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCF49810.1 - 9.5e-10 38.4 0.2 2.6e-09 37.0 0.1 1.7 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CCF49810.1 - 0.03 14.5 0.1 0.06 13.5 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 Rtf2 PF04641.7 CCF49811.1 - 8.2e-71 238.2 1.5 1e-70 237.9 1.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CCF49811.1 - 0.0015 17.9 0.9 0.076 12.5 0.0 3.0 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C2HC_2 PF13913.1 CCF49811.1 - 0.0036 16.9 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type RR_TM4-6 PF06459.7 CCF49811.1 - 2.1 8.1 9.0 3 7.6 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 CCF49811.1 - 2.2 7.7 12.5 3.3 7.1 8.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CCF49811.1 - 7.2 4.5 7.9 9.3 4.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SH3_1 PF00018.23 CCF49813.1 - 1.6e-38 129.8 11.5 2.4e-16 58.8 0.2 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 CCF49813.1 - 2.5e-38 129.4 12.1 1e-13 50.6 0.1 4.6 4 1 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.7 CCF49813.1 - 9.9e-33 111.6 0.0 1.9e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 CCF49813.1 - 8.5e-26 89.2 0.0 2.9e-07 29.8 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 CCF49813.1 - 5e-05 23.4 3.3 0.013 15.6 0.1 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.6 CCF49813.1 - 0.0052 16.8 117.4 0.072 13.1 27.0 4.6 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) Ank_4 PF13637.1 CCF49814.1 - 4e-11 43.1 0.6 6.7e-05 23.2 0.1 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCF49814.1 - 1.5e-09 38.0 0.7 0.0025 18.1 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCF49814.1 - 1.7e-08 33.8 1.9 0.0079 15.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCF49814.1 - 9.2e-06 25.7 3.3 0.019 15.2 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CCF49814.1 - 1.8e-05 24.3 0.2 0.00018 21.0 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 CCF49814.1 - 2.1e-05 24.3 5.4 0.026 14.7 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Filament PF00038.16 CCF49814.1 - 0.0038 16.7 4.8 0.0078 15.7 3.3 1.5 1 0 0 1 1 1 1 Intermediate filament protein OmpH PF03938.9 CCF49814.1 - 0.014 15.3 6.8 0.038 13.9 4.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) His_Phos_1 PF00300.17 CCF49815.1 - 3.7e-41 140.8 0.0 4.4e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SH3_9 PF14604.1 CCF49816.1 - 5.8e-31 105.8 1.2 4.4e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CCF49816.1 - 3e-27 93.7 3.2 3e-15 55.3 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CCF49816.1 - 5e-17 61.1 0.2 6e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 CCF49816.1 - 3.8e-14 52.6 0.0 8e-14 51.6 0.0 1.5 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein RhoGAP PF00620.22 CCF49817.1 - 1.1e-36 125.7 0.1 2.2e-36 124.7 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CCF49817.1 - 8.9e-27 92.9 32.4 4.3e-11 42.7 2.2 5.0 5 0 0 5 5 5 4 LIM domain MEKHLA PF08670.6 CCF49818.1 - 0.019 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 MEKHLA domain CD20 PF04103.10 CCF49818.1 - 0.072 13.0 5.6 0.06 13.2 0.8 2.4 1 1 2 3 3 3 0 CD20-like family DUF2235 PF09994.4 CCF49820.1 - 4.8e-57 193.4 0.0 3.3e-56 190.6 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-CCCH PF00642.19 CCF49821.1 - 3.6e-11 42.4 25.1 2.1e-07 30.4 0.9 4.3 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 CCF49822.1 - 2.1e-14 53.0 31.6 2.1e-14 53.0 21.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCF49822.1 - 4.3e-13 49.0 11.7 2.2e-12 46.7 6.7 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Amidohydro_4 PF13147.1 CCF49823.1 - 1.3e-32 113.9 4.1 3.2e-32 112.6 0.4 2.6 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 CCF49823.1 - 6.5e-15 54.7 0.6 1.2e-11 44.2 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CCF49823.1 - 1.3e-08 34.9 0.0 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 CCF49823.1 - 7.6e-05 22.1 1.8 0.19 10.8 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Prenyltrans PF00432.16 CCF49824.1 - 4.4e-30 102.9 4.9 2.1e-06 27.1 0.0 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCF49824.1 - 4.7e-17 62.4 0.4 1.9e-13 50.8 0.0 3.6 3 0 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCF49824.1 - 0.027 14.4 0.0 0.19 11.7 0.0 2.4 1 1 0 1 1 1 0 Prenyltransferase-like DUF4451 PF14616.1 CCF49825.1 - 1.5e-28 99.0 2.2 1.5e-28 99.0 1.5 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4451) Thioredoxin PF00085.15 CCF49826.1 - 1.2e-26 92.3 0.1 6.4e-26 90.0 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CCF49826.1 - 1.3e-06 28.5 0.3 1.3e-06 28.5 0.2 3.3 4 2 1 5 5 5 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF49826.1 - 9.7e-05 22.4 0.0 0.001 19.1 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CCF49826.1 - 0.00019 21.3 0.0 0.00072 19.5 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CCF49826.1 - 0.0098 15.4 2.3 0.018 14.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin DUF755 PF05501.6 CCF49826.1 - 0.013 15.5 8.7 0.013 15.5 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FtsK_SpoIIIE PF01580.13 CCF49826.1 - 0.033 13.6 0.3 0.081 12.3 0.2 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AhpC-TSA PF00578.16 CCF49826.1 - 0.058 13.0 0.8 0.24 11.1 0.0 2.3 2 1 1 3 3 3 0 AhpC/TSA family PPR_2 PF13041.1 CCF49827.1 - 0.00092 19.1 0.0 17 5.5 0.0 5.4 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 CCF49827.1 - 0.016 15.1 0.4 1.5e+02 2.6 0.0 5.1 5 0 0 5 5 5 0 PPR repeat PPR_1 PF12854.2 CCF49827.1 - 0.099 12.1 0.0 35 4.0 0.1 3.9 4 0 0 4 4 4 0 PPR repeat Methyltransf_11 PF08241.7 CCF49828.1 - 2.3e-14 53.6 0.1 3.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF49828.1 - 3.7e-14 52.7 0.1 4.7e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF49828.1 - 9.2e-14 51.7 0.1 1.5e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF49828.1 - 6.6e-13 48.5 0.1 9.5e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF49828.1 - 4.7e-12 46.4 0.0 7.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF49828.1 - 1e-07 31.5 0.1 1.4e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CCF49828.1 - 2.2e-07 29.8 0.1 2.9e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 CCF49828.1 - 5.2e-07 29.2 0.1 7.4e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 CCF49828.1 - 2e-06 28.0 0.0 3.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF49828.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCF49828.1 - 3.4e-05 23.0 0.0 6.3e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 CCF49828.1 - 0.00011 21.4 0.1 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 CCF49828.1 - 0.00013 21.1 0.1 0.00091 18.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.6 CCF49828.1 - 0.0003 19.6 0.1 0.00068 18.4 0.0 1.6 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase NodS PF05401.6 CCF49828.1 - 0.00065 19.1 0.0 0.00091 18.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 CCF49828.1 - 0.0035 16.5 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB FmrO PF07091.6 CCF49828.1 - 0.0038 16.2 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) CMAS PF02353.15 CCF49828.1 - 0.007 15.4 0.1 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 CCF49828.1 - 0.023 13.5 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.12 CCF49828.1 - 0.051 12.6 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 CCF49828.1 - 0.06 12.8 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CCF49828.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MBOAT PF03062.14 CCF49829.1 - 1.5e-35 122.8 3.8 1.5e-35 122.8 2.6 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CCF49829.1 - 0.00043 20.2 3.3 0.0017 18.4 2.3 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PRP1_N PF06424.7 CCF49829.1 - 0.0094 16.2 8.9 0.019 15.2 6.2 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal Hid1 PF12722.2 CCF49829.1 - 9.1 3.8 10.7 13 3.2 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HSP70 PF00012.15 CCF49831.1 - 3.1e-76 256.5 0.3 4.1e-75 252.8 0.0 2.2 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCF49831.1 - 1.6e-06 26.9 0.7 6.7e-06 24.9 0.1 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CCF49831.1 - 0.0042 16.2 0.1 0.012 14.6 0.1 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Actin PF00022.14 CCF49831.1 - 0.0062 15.0 0.4 0.9 7.8 0.0 2.1 1 1 0 2 2 2 2 Actin FtsA PF14450.1 CCF49831.1 - 0.0063 16.3 2.3 0.34 10.7 0.5 3.3 2 1 0 2 2 2 1 Cell division protein FtsA DUF4445 PF14574.1 CCF49831.1 - 0.015 13.5 0.1 0.022 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4445) PilM_2 PF11104.3 CCF49831.1 - 0.038 12.8 0.0 1.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Ribosomal_L18p PF00861.17 CCF49831.1 - 3.2 7.9 5.8 4.3 7.5 0.2 3.1 4 0 0 4 4 4 0 Ribosomal L18p/L5e family RNase_H2_suC PF08615.6 CCF49832.1 - 1.1e-29 103.0 0.0 2.3e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Histone PF00125.19 CCF49832.1 - 0.03 14.4 0.1 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CDC45 PF02724.9 CCF49832.1 - 0.43 8.5 3.5 0.51 8.2 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein F-protein PF00469.15 CCF49832.1 - 0.44 9.8 3.3 0.74 9.1 2.3 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4611 PF15387.1 CCF49832.1 - 3.1 7.9 8.9 5.9 7.1 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Abhydrolase_2 PF02230.11 CCF49833.1 - 6.4e-17 61.7 0.1 8.5e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CCF49833.1 - 4.4e-05 23.4 0.0 6.9e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF49833.1 - 0.00042 20.0 0.0 0.00063 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCF49833.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.8 CCF49833.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase PF00151.14 CCF49833.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipase ThiS PF02597.15 CCF49834.1 - 2.5e-06 27.8 0.0 2.9e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family TPR_11 PF13414.1 CCF49835.1 - 3.8e-27 93.7 0.4 3.3e-17 61.9 0.5 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCF49835.1 - 1.8e-23 81.0 0.0 1.8e-08 33.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF49835.1 - 2.3e-18 64.5 0.0 1.6e-06 27.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCF49835.1 - 2.8e-11 42.9 0.1 3.7e-05 23.9 0.0 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCF49835.1 - 1.5e-10 40.0 0.0 0.0038 16.9 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49835.1 - 6.3e-10 39.4 0.6 1.1e-05 25.8 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCF49835.1 - 1e-09 37.8 0.1 0.0016 18.4 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF49835.1 - 6.7e-08 31.7 0.0 0.00096 18.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCF49835.1 - 2.6e-07 30.8 0.1 0.0005 20.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCF49835.1 - 7.3e-07 29.0 0.2 2.4e-05 24.1 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 CCF49835.1 - 9.6e-07 29.2 0.1 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 2 Bacterial transcriptional activator domain Apc3 PF12895.2 CCF49835.1 - 0.00025 21.0 0.0 0.021 14.9 0.0 1.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCF49835.1 - 0.00045 20.0 0.0 0.064 13.1 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCF49835.1 - 0.0018 17.4 0.1 0.0035 16.4 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCF49835.1 - 0.0088 15.9 0.1 5.4 7.0 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat XPC-binding PF09280.6 CCF49835.1 - 0.022 14.2 4.3 0.022 14.2 3.0 1.9 2 0 0 2 2 2 0 XPC-binding domain Alkyl_sulf_dimr PF14863.1 CCF49835.1 - 0.025 14.8 0.1 0.79 9.9 0.0 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 CCF49835.1 - 0.032 14.6 1.8 18 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HRDC PF00570.18 CCF49835.1 - 0.16 11.6 1.5 0.82 9.4 0.1 2.5 2 0 0 2 2 2 0 HRDC domain DHHA1 PF02272.14 CCF49835.1 - 0.99 9.1 5.4 2.7 7.7 0.0 2.9 2 1 0 2 2 2 0 DHHA1 domain MIT PF04212.13 CCF49835.1 - 1 9.2 4.8 14 5.6 0.0 3.5 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 CCF49836.1 - 5.6e-44 150.2 0.0 8.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF49836.1 - 6.3e-18 64.7 0.0 1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CCF49836.1 - 1.8e-05 24.2 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CCF49836.1 - 0.0016 18.2 0.0 0.0016 18.2 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCF49836.1 - 0.0083 15.1 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CCF49836.1 - 0.11 12.1 0.1 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Amidase PF01425.16 CCF49837.1 - 1.9e-96 323.6 0.0 2.2e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Cu-oxidase_3 PF07732.10 CCF49838.1 - 1.8e-34 117.9 0.5 6.5e-34 116.1 0.4 2.0 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCF49838.1 - 2.1e-28 98.5 4.0 6.4e-24 84.0 0.3 3.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 CCF49838.1 - 2.2e-17 63.4 0.0 5.2e-14 52.4 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase HMG_CoA_synt_N PF01154.12 CCF49839.1 - 1.9e-85 284.7 0.1 4.2e-85 283.6 0.1 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CCF49839.1 - 3.9e-83 279.2 0.3 5e-83 278.8 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.5 CCF49839.1 - 0.0056 16.6 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CCF49839.1 - 0.021 14.4 0.3 0.077 12.6 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RRM_1 PF00076.17 CCF49840.1 - 6.1e-29 99.4 0.1 9.3e-15 54.0 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49840.1 - 1.9e-18 66.1 0.0 1.7e-06 27.9 0.0 4.2 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF49840.1 - 2.2e-12 46.5 0.1 0.00027 20.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CCF49840.1 - 0.14 11.7 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) FF PF01846.14 CCF49841.1 - 3.7e-24 84.4 4.0 3.2e-10 39.8 0.0 5.6 6 0 0 6 6 6 3 FF domain WW PF00397.21 CCF49841.1 - 1.2e-12 47.4 16.5 1.1e-06 28.3 4.5 2.8 2 0 0 2 2 2 2 WW domain IgG_binding_B PF01378.12 CCF49841.1 - 0.062 13.1 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 B domain AAA_16 PF13191.1 CCF49841.1 - 1.1 9.2 7.1 5.9 6.8 2.5 2.9 1 1 1 2 2 2 0 AAA ATPase domain WD40 PF00400.27 CCF49842.1 - 1.2e-12 47.1 0.5 1 9.3 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Phe_tRNA-synt_N PF02912.13 CCF49845.1 - 0.031 13.9 0.1 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain VPS9 PF02204.13 CCF49846.1 - 2.3e-30 104.6 0.2 4.2e-30 103.8 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CCF49846.1 - 1.2e-10 40.6 0.0 2.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 CCF49846.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif Ctr PF04145.10 CCF49847.1 - 9.6e-39 132.7 1.3 1.3e-38 132.2 0.9 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Zw10 PF06248.8 CCF49849.1 - 2.9e-18 65.3 1.4 1.9e-13 49.4 0.0 2.4 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dor1 PF04124.7 CCF49849.1 - 0.013 14.0 1.4 0.03 12.7 1.0 1.6 1 0 0 1 1 1 0 Dor1-like family Dsl1_C PF11989.3 CCF49849.1 - 0.24 10.5 0.0 0.47 9.5 0.0 1.4 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Cellulase PF00150.13 CCF49850.1 - 2.1e-08 33.7 0.1 3.8e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1752 PF08550.5 CCF49851.1 - 5.9e-12 44.9 2.7 1.2e-11 43.9 1.9 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Dysbindin PF04440.11 CCF49852.1 - 9.1 6.0 17.3 0.076 12.7 4.2 3.2 3 1 0 3 3 3 0 Dysbindin (Dystrobrevin binding protein 1) Flavodoxin_1 PF00258.20 CCF49853.1 - 1.2e-29 103.1 0.0 2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 CCF49853.1 - 7.9e-24 84.3 0.0 3e-23 82.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCF49853.1 - 1.4e-11 44.9 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Sds3 PF08598.6 CCF49854.1 - 8.8e-26 90.7 4.6 8.8e-26 90.7 3.2 2.4 2 1 0 2 2 2 1 Sds3-like Dynamin_M PF01031.15 CCF49855.1 - 7.4e-114 379.4 0.0 1e-113 379.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCF49855.1 - 8.7e-55 185.0 0.0 2.1e-54 183.8 0.0 1.7 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CCF49855.1 - 3.9e-29 100.3 1.6 5.2e-29 99.9 0.4 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCF49855.1 - 0.003 17.5 0.0 0.042 13.8 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCF49855.1 - 0.0078 16.6 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CCF49855.1 - 0.045 12.8 0.1 3.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AIG1 family ATP-synt_ab PF00006.20 CCF49856.1 - 3e-69 232.8 0.0 4.2e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCF49856.1 - 1.3e-23 83.5 0.0 4.7e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCF49856.1 - 3.3e-20 72.0 2.0 8.3e-20 70.7 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCF49856.1 - 1.9e-05 24.4 0.8 4.8e-05 23.1 0.6 1.7 1 1 0 1 1 1 1 HAS barrel domain Ribosomal_L21p PF00829.16 CCF49857.1 - 1.7e-13 50.5 0.3 5.8e-06 26.3 0.8 2.2 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein Vezatin PF12632.2 CCF49858.1 - 7.1e-11 41.6 0.5 1.8e-08 33.8 0.2 2.9 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes DUF3405 PF11885.3 CCF49859.1 - 5e-155 516.5 3.1 5.6e-152 506.4 2.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) G-alpha PF00503.15 CCF49861.1 - 9e-90 301.1 0.0 1.2e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCF49861.1 - 3.3e-12 46.0 0.0 7.3e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 CCF49861.1 - 0.0001 22.4 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCF49861.1 - 0.0056 16.9 0.1 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 CCF49861.1 - 0.014 15.0 0.8 0.022 14.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCF49861.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CCF49861.1 - 0.028 13.8 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF49861.1 - 0.04 13.0 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region cobW PF02492.14 CCF49861.1 - 0.09 12.2 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CCF49861.1 - 0.097 12.4 0.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 CCF49861.1 - 0.11 12.1 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Pox_A32 PF04665.7 CCF49861.1 - 0.24 10.6 0.1 0.5 9.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ribosomal_L28e PF01778.12 CCF49863.1 - 6.7e-31 107.1 0.6 6.7e-31 107.1 0.4 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CCF49863.1 - 7.7e-22 77.2 12.9 7.7e-22 77.2 8.9 3.4 1 1 1 3 3 3 1 Mak16 protein C-terminal region Nop14 PF04147.7 CCF49863.1 - 0.024 12.5 24.9 0.032 12.1 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CCF49863.1 - 0.1 12.4 18.0 0.15 11.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMP_PDE_delta PF05351.6 CCF49863.1 - 0.26 11.0 5.3 5.8 6.7 0.8 2.3 2 0 0 2 2 2 0 GMP-PDE, delta subunit PYC_OADA PF02436.13 CCF49863.1 - 0.32 10.4 3.6 0.13 11.6 0.4 1.9 2 0 0 2 2 2 0 Conserved carboxylase domain SprA-related PF12118.3 CCF49864.1 - 0.0025 17.1 55.5 0.018 14.3 20.4 2.4 2 0 0 2 2 2 2 SprA-related family zf-DHHC PF01529.15 CCF49864.1 - 0.76 9.1 5.3 1.5 8.2 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Suf PF05843.9 CCF49864.1 - 9.3 5.8 30.2 0.94 9.1 11.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PPP4R2 PF09184.6 CCF49864.1 - 9.4 5.6 38.7 1.3 8.5 16.1 2.3 2 0 0 2 2 2 0 PPP4R2 Tim17 PF02466.14 CCF49865.1 - 2.7e-19 69.4 0.6 3.7e-19 69.0 0.1 1.4 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4448 PF14610.1 CCF49866.1 - 6.3e-19 68.2 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4083 PF13314.1 CCF49866.1 - 0.0012 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) RRM_1 PF00076.17 CCF49867.1 - 1.1e-06 28.1 0.9 0.021 14.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF49867.1 - 2.5e-06 27.3 1.3 0.039 13.9 0.0 3.1 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PRKCSH PF07915.8 CCF49867.1 - 8.3 7.3 7.4 39 5.1 0.5 3.0 2 1 0 2 2 2 0 Glucosidase II beta subunit-like protein MFS_1 PF07690.11 CCF49868.1 - 5.3e-34 117.4 37.4 8.6e-34 116.7 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 CCF49868.1 - 0.02 14.4 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 0 Myc target protein 1 Pex2_Pex12 PF04757.9 CCF49868.1 - 0.029 13.8 1.0 0.057 12.8 0.7 1.4 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Polyketide_cyc PF03364.15 CCF49869.1 - 3e-26 91.9 0.0 5.5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Epimerase PF01370.16 CCF49869.1 - 8.2e-08 31.9 0.0 3.3e-06 26.6 0.0 3.2 4 0 0 4 4 4 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCF49869.1 - 1.1e-05 25.4 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Polyketide_cyc2 PF10604.4 CCF49869.1 - 4.2e-05 23.7 0.0 8.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport NAD_binding_10 PF13460.1 CCF49869.1 - 0.00069 19.6 0.0 0.0048 16.9 0.0 2.4 3 0 0 3 3 3 1 NADH(P)-binding KR PF08659.5 CCF49869.1 - 0.022 14.4 0.1 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 KR domain MFS_1 PF07690.11 CCF49870.1 - 3.4e-32 111.5 36.7 1e-26 93.5 14.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF49870.1 - 4.4e-26 91.4 18.6 9.2e-19 67.3 4.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter RCC1_2 PF13540.1 CCF49872.1 - 4e-14 51.7 10.4 0.00011 21.6 0.0 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCF49872.1 - 7.6e-10 38.8 4.8 2 8.7 0.0 6.3 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 CCF49872.1 - 1.5e-06 27.7 0.4 4.3e-06 26.2 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCF49872.1 - 2.8e-05 23.7 0.1 0.0001 21.9 0.1 1.9 2 0 0 2 2 2 1 F-box-like Nop14 PF04147.7 CCF49872.1 - 0.028 12.3 8.8 0.04 11.8 6.1 1.2 1 0 0 1 1 1 0 Nop14-like family Fungal_trans PF04082.13 CCF49873.1 - 2.7e-12 46.1 0.7 5.6e-12 45.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF49873.1 - 5.7e-05 22.9 6.7 0.00012 21.9 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CCF49873.1 - 2.8 8.1 9.1 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region WD40 PF00400.27 CCF49874.1 - 3.6e-40 134.4 2.6 5.6e-08 32.3 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 CCF49874.1 - 1.2e-14 54.3 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Nucleoporin_N PF08801.6 CCF49874.1 - 0.028 13.2 0.0 1.7 7.2 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Peptidase_A2E PF12382.3 CCF49874.1 - 0.22 11.3 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase PCNA_N PF00705.13 CCF49875.1 - 1.7e-48 163.3 1.9 2.8e-48 162.6 0.9 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCF49875.1 - 2e-43 147.3 0.3 4e-22 78.4 0.1 2.5 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CCF49875.1 - 2.6e-05 23.4 0.1 6.6e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Rad9 DUF4236 PF14020.1 CCF49875.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Sec34 PF04136.10 CCF49876.1 - 3e-17 62.7 0.2 7.8e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family Actin PF00022.14 CCF49877.1 - 9.4e-117 389.7 0.0 1.2e-116 389.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCF49877.1 - 0.017 13.7 0.0 0.061 11.9 0.0 1.8 1 1 0 1 1 1 0 MreB/Mbl protein PX PF00787.19 CCF49878.1 - 6.5e-14 51.6 0.0 1.8e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 CCF49878.1 - 1.5e-09 37.4 6.9 2.3e-09 36.7 4.8 1.3 1 0 0 1 1 1 1 SNARE domain Macoilin PF09726.4 CCF49878.1 - 0.014 13.7 0.5 0.018 13.3 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein FliJ PF02050.11 CCF49878.1 - 0.05 13.6 8.7 0.16 12.0 6.1 1.7 1 1 0 1 1 1 0 Flagellar FliJ protein DUF745 PF05335.8 CCF49878.1 - 0.39 10.2 4.4 0.67 9.4 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NPV_P10 PF05531.7 CCF49878.1 - 2.2 8.5 5.3 14 6.0 2.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Aldedh PF00171.17 CCF49879.1 - 3e-158 526.9 0.0 3.5e-158 526.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF49879.1 - 0.00076 18.3 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Neurochondrin PF05536.6 CCF49879.1 - 0.03 12.6 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin DUF1487 PF07368.6 CCF49879.1 - 0.063 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) UCH PF00443.24 CCF49880.1 - 5.2e-66 222.5 0.0 9.6e-66 221.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF49880.1 - 3.1e-24 85.9 0.0 4.6e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 CCF49880.1 - 2e-06 27.7 0.7 4.8e-06 26.5 0.3 1.8 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 CCF49880.1 - 0.0016 18.7 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 CCF49880.1 - 0.029 13.8 0.5 0.063 12.8 0.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DivIVA PF05103.8 CCF49880.1 - 0.053 13.5 3.6 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 DivIVA protein Plus-3 PF03126.13 CCF49881.1 - 1.7e-09 37.6 0.0 4.4e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Plus-3 domain TPR_11 PF13414.1 CCF49883.1 - 7.4e-46 153.6 18.2 6.8e-15 54.4 0.8 5.6 3 2 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 CCF49883.1 - 1.3e-35 119.4 9.8 1.3e-05 24.6 0.2 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 CCF49883.1 - 2.4e-33 111.3 12.9 0.00035 20.2 0.1 8.9 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 CCF49883.1 - 4.2e-24 84.6 16.6 5.8e-09 36.1 1.1 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat DnaJ PF00226.26 CCF49883.1 - 2.4e-22 78.4 2.9 5.6e-22 77.2 2.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 CCF49883.1 - 1.4e-21 75.0 17.5 1.8e-05 24.9 0.5 8.2 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCF49883.1 - 1.3e-17 63.5 22.2 7.7e-06 25.7 0.0 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCF49883.1 - 3.7e-17 62.5 27.4 1.8e-08 34.8 1.7 6.2 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCF49883.1 - 3.9e-12 45.0 5.1 0.11 12.2 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCF49883.1 - 6.4e-11 41.5 10.3 0.0065 16.5 0.1 7.1 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCF49883.1 - 3.7e-09 35.7 10.5 0.39 10.6 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCF49883.1 - 3e-08 33.4 18.3 0.00018 21.2 0.8 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CCF49883.1 - 2.7e-07 30.6 14.3 0.0093 16.0 0.1 4.7 2 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCF49883.1 - 7.5e-07 29.1 9.6 6.2 7.5 0.1 7.2 8 0 0 8 8 7 2 Tetratricopeptide repeat Coatomer_E PF04733.9 CCF49883.1 - 0.011 14.9 3.7 0.19 10.9 0.1 3.3 3 1 1 4 4 4 0 Coatomer epsilon subunit SHNi-TPR PF10516.4 CCF49883.1 - 0.06 12.5 5.2 0.098 11.9 0.1 3.4 4 0 0 4 4 4 0 SHNi-TPR DUF3856 PF12968.2 CCF49883.1 - 0.17 11.7 7.7 0.2 11.4 1.5 3.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 CCF49883.1 - 0.31 11.5 18.7 0.14 12.6 0.5 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat Dispanin PF04505.7 CCF49883.1 - 1.1 8.8 2.8 4.8 6.7 0.1 3.1 3 0 0 3 3 3 0 Interferon-induced transmembrane protein TPR_20 PF14561.1 CCF49883.1 - 4.1 7.5 19.9 0.13 12.3 0.6 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCF49883.1 - 4.5 7.2 12.8 11 6.0 0.0 5.6 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat PseudoU_synth_1 PF01416.15 CCF49884.1 - 1.6e-18 67.0 0.0 6.9e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase WD40 PF00400.27 CCF49885.1 - 1.7e-50 167.1 28.6 3.5e-11 42.5 0.4 9.0 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CCF49885.1 - 1.5e-10 40.6 0.8 3.3e-10 39.5 0.6 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CCF49885.1 - 7.1e-10 37.6 6.3 0.11 10.6 0.0 5.3 2 2 3 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 CCF49885.1 - 0.00095 18.7 1.6 0.002 17.7 1.1 1.6 1 0 0 1 1 1 1 F-box domain Nramp PF01566.13 CCF49887.1 - 2e-87 293.3 15.2 5.8e-49 166.7 2.1 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein NAD_binding_4 PF07993.7 CCF49888.1 - 2.5e-27 95.4 0.0 3.4e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCF49888.1 - 0.00084 18.8 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GSK-3_bind PF05350.7 CCF49888.1 - 0.023 14.1 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Semialdhyde_dh PF01118.19 CCF49888.1 - 0.057 13.7 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF49888.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding Amino_oxidase PF01593.19 CCF49889.1 - 7.1e-10 38.5 0.0 7.5e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribosomal_L24e PF01246.15 CCF49891.1 - 2.1e-28 97.9 3.4 4.5e-28 96.9 2.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Transglut_N PF00868.15 CCF49891.1 - 0.012 15.6 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase family zf-CCCH PF00642.19 CCF49892.1 - 5.3e-17 61.0 34.9 7.9e-05 22.2 0.8 5.7 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CCF49892.1 - 2.5e-06 27.1 1.3 1.5e-05 24.6 0.9 2.5 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 CCF49893.1 - 1.2e-05 24.8 1.7 3.1e-05 23.5 1.1 1.8 1 1 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF49893.1 - 0.00022 21.2 0.1 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Zn_clus PF00172.13 CCF49895.1 - 0.0012 18.6 5.8 0.0024 17.7 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2515 PF10720.4 CCF49895.1 - 0.05 12.5 0.5 0.094 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2515) WD40 PF00400.27 CCF49896.1 - 1.3e-55 183.4 9.1 3.2e-10 39.4 0.0 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 CCF49896.1 - 2.7e-07 29.7 5.8 6.5e-07 28.4 4.0 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 CCF49896.1 - 2.2e-05 22.8 4.9 0.039 12.0 0.1 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCF49896.1 - 8.3e-05 21.8 1.1 0.018 14.1 0.0 3.6 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal BAF1_ABF1 PF04684.8 CCF49896.1 - 0.00028 19.8 1.1 0.00045 19.2 0.8 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor eIF2A PF08662.6 CCF49896.1 - 0.0014 18.3 0.0 1.6 8.4 0.0 3.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Methyltransf_24 PF13578.1 CCF49896.1 - 0.1 13.4 0.2 5.7 7.8 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain PMT PF02366.13 CCF49897.1 - 7.5e-80 267.8 15.5 7.5e-80 267.8 10.7 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCF49897.1 - 5.6e-21 74.9 0.6 1.1e-20 74.0 0.4 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CCF49897.1 - 5e-06 26.5 14.4 5e-06 26.5 10.0 2.9 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SBDS_C PF09377.5 CCF49898.1 - 2.2e-43 146.9 1.3 4e-43 146.0 0.9 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CCF49898.1 - 1.2e-30 105.0 0.8 4.3e-30 103.3 0.2 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Noc2 PF03715.8 CCF49899.1 - 2.5e-102 341.7 0.5 4.1e-102 341.0 0.4 1.3 1 0 0 1 1 1 1 Noc2p family AAA_25 PF13481.1 CCF49900.1 - 0.00073 18.9 0.2 0.003 16.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CCF49900.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 CCF49900.1 - 0.078 12.8 1.3 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain RNA12 PF10443.4 CCF49900.1 - 0.14 10.6 0.0 0.27 9.6 0.0 1.5 1 1 0 1 1 1 0 RNA12 protein Polysacc_deac_1 PF01522.16 CCF49901.1 - 4.8e-06 26.1 0.0 9.1e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase STE3 PF02076.10 CCF49904.1 - 4.8e-95 317.8 17.2 5.6e-95 317.6 11.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor UPF0139 PF03669.8 CCF49905.1 - 0.0031 16.9 0.0 0.0043 16.5 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) YhhN PF07947.9 CCF49905.1 - 0.016 14.6 0.2 0.018 14.4 0.1 1.1 1 0 0 1 1 1 0 YhhN-like protein Pantoate_ligase PF02569.10 CCF49906.1 - 3.8e-80 268.6 0.0 6.2e-80 267.9 0.0 1.4 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CBP4 PF07960.6 CCF49907.1 - 8.9e-07 28.5 0.2 9.7e-07 28.4 0.1 1.0 1 0 0 1 1 1 1 CBP4 DUF4414 PF14377.1 CCF49907.1 - 0.0071 16.2 0.6 0.008 16.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) DAHP_synth_1 PF00793.15 CCF49908.1 - 5.1e-92 307.4 0.0 6e-92 307.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_S19 PF00203.16 CCF49909.1 - 4e-25 87.2 0.0 5.1e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 OPT PF03169.10 CCF49910.1 - 7.1e-157 523.5 40.6 8.2e-157 523.3 28.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RVT_1 PF00078.22 CCF49913.1 - 2.2e-25 89.3 0.0 4.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49913.1 - 3.4e-20 72.3 0.0 6.9e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49913.1 - 4.8e-12 45.3 1.2 1.7e-11 43.6 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 CCF49914.1 - 0.00049 20.1 0.1 0.00091 19.2 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Phage_tail_S PF05069.8 CCF49914.1 - 0.11 12.3 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Phage virion morphogenesis family Iso_dh PF00180.15 CCF49916.1 - 6.6e-09 35.1 0.1 2.5e-08 33.2 0.0 1.7 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Pro_3_hydrox_C PF05373.6 CCF49916.1 - 0.036 14.0 0.2 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Ten1_2 PF15490.1 CCF49916.1 - 0.062 12.8 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit Vps35 PF03635.12 CCF49918.1 - 0 1148.8 0.0 0 1148.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 zf-CCHC PF00098.18 CCF49919.1 - 2.1e-06 27.3 1.2 5.3e-06 26.1 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 CCF49920.1 - 1.1e-58 198.1 0.6 1.4e-56 191.2 0.4 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49920.1 - 1.3e-14 54.3 0.1 2.7e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CCF49921.1 - 1.8e-05 24.4 2.7 4.1e-05 23.2 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 CCF49921.1 - 0.0029 17.2 0.1 0.011 15.3 0.1 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.22 CCF49922.1 - 3e-25 88.8 0.0 5.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49922.1 - 6e-19 68.3 0.0 1.4e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49922.1 - 1.4e-11 43.8 1.5 2.5e-11 43.0 0.2 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CCF49922.1 - 0.009 15.5 2.5 0.0099 15.3 0.2 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 CCF49922.1 - 0.011 15.7 1.5 0.029 14.4 0.2 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.18 CCF49922.1 - 0.022 14.7 0.4 0.064 13.2 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 CCF49923.1 - 1.9e-72 243.2 0.0 3.3e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49923.1 - 9.5e-10 38.6 0.1 2e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain Ipi1_N PF12333.3 CCF49923.1 - 0.011 15.7 0.1 0.041 13.8 0.0 2.0 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation DDE_3 PF13358.1 CCF49925.1 - 5.9e-18 65.0 0.2 7.8e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.1 CCF49926.1 - 3.6e-06 26.6 0.0 9.2e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_37 PF13744.1 CCF49926.1 - 0.017 14.9 0.5 0.034 13.9 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Orbi_VP2 PF00898.12 CCF49926.1 - 0.12 9.9 1.1 0.15 9.5 0.8 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 RAP1 PF07218.6 CCF49928.1 - 0.22 9.5 3.7 0.26 9.3 2.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF605 PF04652.11 CCF49928.1 - 5.7 6.2 14.8 6.5 6.0 10.2 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 CCF49928.1 - 8.8 4.1 21.6 9.8 3.9 15.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) gag_pre-integrs PF13976.1 CCF49929.1 - 2.4e-05 23.8 3.2 7.4e-05 22.3 2.2 1.9 1 1 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF49929.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain AAA PF00004.24 CCF49930.1 - 1.3e-44 151.6 0.1 3.7e-44 150.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCF49930.1 - 7.9e-09 35.3 0.6 2.7e-08 33.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCF49930.1 - 6.5e-08 32.6 0.0 1.6e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCF49930.1 - 4.4e-07 30.1 0.5 0.00033 20.7 0.3 3.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF49930.1 - 1.9e-06 27.9 0.9 5.5e-06 26.4 0.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CCF49930.1 - 4.1e-06 25.8 0.2 1.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCF49930.1 - 0.00021 21.2 0.4 0.00081 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCF49930.1 - 0.00037 20.2 0.2 0.0029 17.3 0.0 2.5 3 0 0 3 3 2 1 NTPase AAA_19 PF13245.1 CCF49930.1 - 0.00049 19.7 0.2 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCF49930.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCF49930.1 - 0.00057 18.9 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CCF49930.1 - 0.00096 18.8 0.1 0.034 13.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CCF49930.1 - 0.0012 19.6 0.0 0.0049 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 CCF49930.1 - 0.0018 18.4 0.0 0.0065 16.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_30 PF13604.1 CCF49930.1 - 0.0022 17.5 0.0 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF49930.1 - 0.0023 18.2 0.1 0.015 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCF49930.1 - 0.0031 17.2 1.0 0.067 12.8 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 CCF49930.1 - 0.0035 17.2 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCF49930.1 - 0.0039 15.9 0.0 0.0075 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CCF49930.1 - 0.0045 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCF49930.1 - 0.0057 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCF49930.1 - 0.0073 15.4 0.5 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 CCF49930.1 - 0.0081 15.7 2.7 0.025 14.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCF49930.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CCF49930.1 - 0.013 15.1 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CCF49930.1 - 0.013 14.9 0.8 0.026 13.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 CCF49930.1 - 0.017 14.5 4.9 0.027 13.8 0.1 2.7 2 1 1 3 3 3 0 AAA domain Bac_DnaA PF00308.13 CCF49930.1 - 0.022 14.3 0.1 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_23 PF13476.1 CCF49930.1 - 0.028 14.7 4.8 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CCF49930.1 - 0.041 13.0 0.8 0.17 11.0 0.0 2.2 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 CCF49930.1 - 0.049 13.6 0.2 0.97 9.4 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCF49930.1 - 0.052 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CCF49930.1 - 0.065 12.7 0.2 1.4 8.3 0.0 2.8 3 1 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.22 CCF49930.1 - 0.12 12.6 0.2 0.84 9.9 0.0 2.5 3 1 0 3 3 2 0 ABC transporter AAA_10 PF12846.2 CCF49930.1 - 1.3 8.4 3.6 1.4 8.2 0.1 2.6 3 1 1 4 4 4 0 AAA-like domain DUF2076 PF09849.4 CCF49931.1 - 8.5e-09 35.8 13.1 1.1e-08 35.4 9.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CCF49931.1 - 0.00042 20.1 6.8 0.00066 19.5 4.7 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CCF49931.1 - 0.31 11.1 3.6 0.55 10.3 0.2 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Nucleoporin_FG PF13634.1 CCF49931.1 - 6.8 6.9 21.0 14 5.9 14.6 1.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region RVT_1 PF00078.22 CCF49933.1 - 2.7e-09 36.6 0.2 8e-09 35.1 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49933.1 - 0.084 12.9 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.18 CCF49935.1 - 8.2e-05 22.3 1.7 0.00017 21.3 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 CCF49936.1 - 1.8e-66 223.6 0.0 5.4e-66 222.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49936.1 - 2.7e-19 69.4 0.1 9.9e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain TSP_1 PF00090.14 CCF49936.1 - 0.032 14.3 0.4 0.089 12.9 0.3 1.7 1 0 0 1 1 1 0 Thrombospondin type 1 domain DDE_3 PF13358.1 CCF49938.1 - 5.9e-13 48.7 0.2 1.1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 CCF49938.1 - 4.5e-09 36.2 2.9 5.6e-09 35.9 1.0 1.9 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 CCF49938.1 - 0.0028 17.2 0.0 0.012 15.2 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain GerE PF00196.14 CCF49938.1 - 0.0045 16.2 0.1 0.075 12.3 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_32 PF13565.1 CCF49938.1 - 0.0097 16.6 0.0 0.029 15.1 0.0 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 CCF49938.1 - 0.027 13.6 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_29 PF13551.1 CCF49938.1 - 0.032 14.3 0.0 0.5 10.5 0.0 2.6 2 1 0 2 2 2 0 Winged helix-turn helix HTH_Mga PF08280.6 CCF49938.1 - 0.56 9.9 2.8 21 4.9 0.0 3.1 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Fungal_trans PF04082.13 CCF49939.1 - 1.3e-09 37.2 0.0 2.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF49939.1 - 2.9e-06 27.0 8.8 5.2e-06 26.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain rve PF00665.21 CCF49941.1 - 5.7e-20 71.6 0.0 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49941.1 - 6.1e-13 48.2 1.2 2.2e-12 46.4 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CCF49941.1 - 8.3e-11 41.6 0.1 4.6e-06 26.1 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 CCF49941.1 - 0.14 11.7 1.2 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.12 CCF49942.1 - 0.00089 19.2 0.3 0.0018 18.3 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCF49942.1 - 0.094 12.6 0.7 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.12 CCF49943.1 - 0.0038 17.2 0.1 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein RCC1 PF00415.13 CCF49944.1 - 2.6e-32 110.7 12.6 2.9e-05 24.1 0.0 8.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCF49944.1 - 5.8e-28 95.8 22.1 9.3e-08 31.4 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat FAM176 PF14851.1 CCF49944.1 - 0.28 10.8 3.3 0.43 10.2 2.3 1.3 1 0 0 1 1 1 0 FAM176 family EBV-NA3 PF05009.7 CCF49944.1 - 1.2 8.3 2.9 1.8 7.7 2.0 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DDE_Tnp_4 PF13359.1 CCF49945.1 - 2.2e-13 50.1 0.3 1.3e-06 28.1 0.1 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease MT-A70 PF05063.9 CCF49945.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 MT-A70 DUF883 PF05957.8 CCF49947.1 - 0.02 15.2 1.1 0.054 13.9 0.8 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CCF49947.1 - 0.034 13.6 0.2 0.061 12.8 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain OPA3 PF07047.7 CCF49948.1 - 2.1e-32 111.6 0.8 4.4e-32 110.6 0.6 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) RVT_2 PF07727.9 CCF49950.1 - 0.0048 15.8 0.1 0.0064 15.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Defensin_beta PF00711.14 CCF49951.1 - 0.041 13.7 0.4 0.041 13.7 0.3 1.8 2 0 0 2 2 2 0 Beta defensin RVT_1 PF00078.22 CCF49952.1 - 6.9e-22 77.8 0.1 1.6e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Clp_N PF02861.15 CCF49952.1 - 0.16 11.8 1.5 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Clp amino terminal domain zf-CCHC PF00098.18 CCF49953.1 - 4.2e-06 26.4 2.5 7.1e-06 25.7 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CCF49953.1 - 0.00076 18.9 0.4 0.0019 17.6 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCF49953.1 - 0.0087 15.9 0.8 0.0087 15.9 0.5 2.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.1 CCF49953.1 - 0.11 12.1 0.8 0.31 10.7 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 CCF49953.1 - 0.19 11.2 2.0 0.41 10.1 1.4 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PAT1 PF09770.4 CCF49953.1 - 0.84 7.8 9.2 0.86 7.7 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec2p PF06428.6 CCF49954.1 - 4e-16 58.6 6.6 4e-16 58.6 4.6 3.9 3 2 0 3 3 3 1 GDP/GTP exchange factor Sec2p DUF948 PF06103.6 CCF49954.1 - 0.56 10.1 4.3 4.8 7.1 0.3 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec7 PF01369.15 CCF49955.1 - 2.6e-39 134.8 0.0 6.5e-39 133.5 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 CCF49955.1 - 1.3e-30 106.0 0.0 2.5e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCF49955.1 - 9.6e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Glyco_transf_20 PF00982.16 CCF49956.1 - 5.3e-151 503.3 0.0 7.5e-151 502.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCF49956.1 - 2.6e-19 69.0 0.0 5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase RVT_2 PF07727.9 CCF49957.1 - 4.7e-59 199.3 0.5 1e-58 198.2 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49958.1 - 7.3e-16 58.3 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF49958.1 - 8.9e-06 25.2 3.1 2.6e-05 23.7 2.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Ipi1_N PF12333.3 CCF49959.1 - 0.0094 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation DDE_Tnp_4 PF13359.1 CCF49960.1 - 1.1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease SH3_2 PF07653.12 CCF49960.1 - 0.14 11.6 0.3 0.62 9.5 0.1 2.2 2 1 0 2 2 2 0 Variant SH3 domain Cupin_5 PF06172.6 CCF49961.1 - 2e-18 66.6 0.0 4.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) Mito_carr PF00153.22 CCF49963.1 - 1.4e-15 56.8 9.3 1.9e-05 24.2 0.0 6.0 5 1 0 5 5 5 5 Mitochondrial carrier protein Sec7_N PF12783.2 CCF49965.1 - 8.9e-35 119.5 0.2 3.2e-34 117.7 0.1 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCF49965.1 - 0.00013 21.3 0.0 0.0072 15.8 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Extensin_2 PF04554.8 CCF49967.1 - 3.4 7.6 9.2 13 5.6 6.4 2.0 1 1 0 1 1 1 0 Extensin-like region RVT_2 PF07727.9 CCF49968.1 - 4.3e-16 58.6 0.0 5.2e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_kinase PF01513.16 CCF49969.1 - 1.4e-66 224.1 0.0 3.4e-66 222.9 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Nucleo_P87 PF07267.6 CCF49969.1 - 2.9 6.4 24.8 1.1 7.8 4.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RVT_2 PF07727.9 CCF49970.1 - 2.9e-72 242.6 0.0 7.7e-72 241.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49970.1 - 1.4e-19 70.3 0.1 8.1e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCF49970.1 - 1.2e-07 31.2 0.4 3.3e-07 29.8 0.3 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.9 CCF49971.1 - 3.2e-15 55.7 0.0 4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF49973.1 - 2.3e-23 82.6 0.0 4.5e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF49973.1 - 9.3e-20 70.9 0.0 2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF49973.1 - 4.1e-12 45.5 1.3 7.9e-12 44.6 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 CCF49973.1 - 1.1e-08 35.4 0.2 2.6e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCF49973.1 - 5.1e-07 29.7 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CCF49973.1 - 0.0027 17.7 0.1 0.011 15.7 0.0 2.1 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.15 CCF49973.1 - 0.01 15.7 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 CCF49973.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease rve_3 PF13683.1 CCF49973.1 - 0.31 10.5 2.7 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Auxin_repressed PF05564.7 CCF49975.1 - 0.74 10.4 3.3 0.56 10.8 1.6 1.3 1 1 0 1 1 1 0 Dormancy/auxin associated protein RVT_1 PF00078.22 CCF49977.1 - 9.5e-14 51.2 0.2 1.8e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_Tnp_4 PF13359.1 CCF49980.1 - 7e-11 41.9 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 CCF49980.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain NUDIX_2 PF13869.1 CCF49982.1 - 5.3e-74 247.6 0.0 6.4e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase TBP PF00352.16 CCF49983.1 - 3.4e-67 221.8 0.2 7e-33 111.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCF49983.1 - 8.2e-05 22.5 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Ferric_reduct PF01794.14 CCF49984.1 - 2.2e-17 63.3 7.7 2.2e-17 63.3 5.3 3.3 3 2 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCF49984.1 - 1.4e-16 60.2 0.0 3.4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCF49984.1 - 8.6e-16 58.2 0.0 2.6e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CCF49984.1 - 0.0017 18.9 0.0 3.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF3328 PF11807.3 CCF49984.1 - 0.097 12.3 0.4 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Retrotrans_gag PF03732.12 CCF49986.1 - 0.00015 21.7 0.2 0.00037 20.4 0.2 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-rbx1 PF12678.2 CCF49991.1 - 1.1e-13 51.0 0.4 2.3e-13 50.0 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCF49991.1 - 6.4e-11 41.9 7.9 3.3e-10 39.6 5.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCF49991.1 - 3e-07 29.9 0.4 7.8e-07 28.6 0.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF49991.1 - 1.6e-06 27.7 1.1 4.3e-06 26.3 0.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCF49991.1 - 3.9e-06 26.4 3.1 0.00024 20.7 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF49991.1 - 1.2e-05 25.1 2.7 1.2e-05 25.1 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF49991.1 - 0.00088 18.9 1.1 0.00088 18.9 0.8 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCF49991.1 - 0.00089 19.0 2.4 0.0021 17.8 1.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCF49991.1 - 0.0025 17.6 4.7 0.011 15.5 3.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCF49991.1 - 0.003 17.4 0.4 0.0066 16.3 0.3 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 CCF49991.1 - 0.73 9.4 2.7 1.1 8.9 0.8 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SET PF00856.23 CCF49992.1 - 3.5e-09 37.1 2.7 2.8e-08 34.2 0.0 3.5 3 0 0 3 3 3 1 SET domain RVT_2 PF07727.9 CCF49993.1 - 3.1e-07 29.6 0.4 1.1e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CCF49995.1 - 0.01 15.6 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle GDA1_CD39 PF01150.12 CCF49998.1 - 2.7e-88 296.3 0.0 3.7e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CCF49998.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family P5CR_dimer PF14748.1 CCF49999.1 - 1.7e-37 127.7 2.8 1.7e-37 127.7 1.9 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCF49999.1 - 2e-14 53.7 1.2 1e-12 48.3 0.8 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCF49999.1 - 0.036 13.4 0.2 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain zf-CCHC PF00098.18 CCF50002.1 - 7.2e-06 25.6 1.3 1.7e-05 24.5 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle Ion_trans PF00520.26 CCF50003.1 - 3.2e-05 23.2 0.1 6.1e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 Ion transport protein DUF1213 PF06740.7 CCF50006.1 - 0.08 13.0 5.3 1.4 9.0 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) Drc1-Sld2 PF11719.3 CCF50007.1 - 1.5e-15 57.2 5.5 1.5e-15 57.2 3.8 2.1 2 0 0 2 2 2 1 DNA replication and checkpoint protein rve PF00665.21 CCF50011.1 - 2e-05 24.6 0.0 4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-RING_5 PF14634.1 CCF50014.1 - 0.0046 16.6 0.1 0.0046 16.6 0.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCF50014.1 - 0.0051 16.6 0.4 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CCF50014.1 - 0.06 13.0 0.2 0.06 13.0 0.1 2.1 2 1 0 2 2 2 0 RING-type zinc-finger UBN2 PF14223.1 CCF50015.1 - 0.018 14.7 0.6 0.044 13.5 0.2 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF493 PF04359.9 CCF50015.1 - 0.1 12.9 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF493) IL12 PF03039.9 CCF50015.1 - 0.25 10.4 3.2 1.7 7.7 0.2 2.5 1 1 1 2 2 2 0 Interleukin-12 alpha subunit RVT_1 PF00078.22 CCF50016.1 - 5.5e-24 84.7 0.1 1.1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF50016.1 - 4.4e-22 78.4 0.0 3e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 CCF50016.1 - 1.3e-08 35.2 0.2 2.4e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCF50016.1 - 3.4e-07 30.2 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CCF50016.1 - 0.0016 18.4 0.1 0.0055 16.7 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.15 CCF50016.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 CCF50016.1 - 0.014 15.3 2.1 0.031 14.2 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease PF09668.5 CCF50016.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease eIF3g PF12353.3 CCF50016.1 - 0.077 12.9 0.5 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 CCF50016.1 - 0.61 9.6 3.1 0.34 10.4 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L30 PF00327.15 CCF50017.1 - 2.9e-11 42.7 0.0 4.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Herpes_capsid PF06112.6 CCF50019.1 - 8 6.4 8.6 13 5.7 6.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DDE_Tnp_4 PF13359.1 CCF50020.1 - 4.5e-22 78.3 0.0 9.9e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease ACR_tran PF00873.14 CCF50020.1 - 0.21 8.9 0.5 0.31 8.4 0.3 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HTH_37 PF13744.1 CCF50020.1 - 0.41 10.4 5.3 0.49 10.2 2.7 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain RVT_2 PF07727.9 CCF50021.1 - 7.3e-75 251.1 0.0 1.6e-74 249.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF50021.1 - 3.4e-16 59.4 0.1 1.6e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCF50021.1 - 1.8e-07 30.6 0.2 5.2e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCF50021.1 - 0.00014 21.6 2.7 0.00014 21.6 1.9 1.9 2 0 0 2 2 2 1 Zinc knuckle RVT_2 PF07727.9 CCF50026.1 - 1.1e-68 230.8 0.0 2.3e-68 229.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF50026.1 - 8.6e-18 64.5 0.1 4.2e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCF50026.1 - 8.5e-08 31.7 0.4 2.7e-07 30.1 0.3 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCF50026.1 - 5.6e-05 22.8 2.7 0.00014 21.6 1.9 1.7 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.15 CCF50026.1 - 0.027 14.3 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease RabGAP-TBC PF00566.13 CCF50027.1 - 9.1e-37 126.6 0.0 1.7e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADSL_C PF10397.4 CCF50027.1 - 0.11 12.5 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Pkinase PF00069.20 CCF50028.1 - 5e-60 202.8 0.0 6.7e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50028.1 - 1.8e-24 86.2 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50028.1 - 1.5e-05 24.1 0.0 2.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCF50028.1 - 0.0034 17.1 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCF50028.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 CCF50028.1 - 0.059 11.9 0.1 0.1 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Tannase PF07519.6 CCF50029.1 - 2.5e-82 277.1 0.3 1.1e-43 149.7 0.3 2.4 2 1 0 2 2 2 2 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 CCF50029.1 - 7.2e-05 22.5 0.1 0.0022 17.7 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF50029.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF50029.1 - 0.011 14.9 0.1 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_38 PF01074.17 CCF50030.1 - 1.3e-82 277.1 0.9 1.9e-82 276.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CCF50030.1 - 4.9e-54 183.8 0.0 7.1e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CCF50030.1 - 1.5e-26 92.3 0.0 3.2e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Bet_v_1 PF00407.14 CCF50031.1 - 0.046 13.3 0.1 0.099 12.2 0.0 1.5 2 0 0 2 2 2 0 Pathogenesis-related protein Bet v I family DDE_Tnp_4 PF13359.1 CCF50033.1 - 6.3e-19 68.1 0.0 9.8e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_2 PF13696.1 CCF50034.1 - 1.4e-05 24.5 0.8 3.4e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CCF50034.1 - 1.9e-05 24.3 2.1 3.5e-05 23.5 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCF50034.1 - 0.05 13.5 1.3 0.13 12.1 0.9 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RVT_1 PF00078.22 CCF50035.1 - 2.7e-19 69.3 0.7 6.4e-19 68.1 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF50039.1 - 3.8e-34 117.7 0.0 5.3e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF50039.1 - 0.0014 18.7 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1440 PF07274.7 CCF50040.1 - 0.028 14.3 0.7 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) HoxA13_N PF12284.3 CCF50040.1 - 0.06 13.4 0.6 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Hox protein A13 N terminal NARP1 PF12569.3 CCF50041.1 - 1.8e-189 630.7 5.7 1.8e-189 630.7 3.9 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 CCF50041.1 - 4.8e-11 43.0 30.1 0.034 14.8 0.0 11.1 10 3 1 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50041.1 - 3.7e-10 38.9 32.6 1.2e-06 28.0 0.1 10.1 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCF50041.1 - 1.2e-09 37.3 3.5 4.9e-06 25.9 0.1 5.5 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF50041.1 - 1.2e-08 34.7 18.1 0.44 11.3 0.0 10.8 11 2 1 12 12 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF50041.1 - 1.5e-08 33.8 4.1 2e-05 24.0 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCF50041.1 - 5.5e-08 33.0 29.7 0.0016 18.7 0.1 9.0 8 2 3 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF50041.1 - 1e-07 31.7 25.6 0.002 18.0 0.1 8.0 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF50041.1 - 2.1e-06 27.1 8.2 0.01 15.5 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF50041.1 - 6.8e-06 26.1 2.3 0.13 12.4 0.1 5.8 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CCF50041.1 - 1.2e-05 24.8 0.2 1.2e-05 24.8 0.2 7.3 8 2 0 9 9 8 2 TPR repeat TPR_6 PF13174.1 CCF50041.1 - 0.00017 21.8 18.1 0.42 11.1 0.0 9.6 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCF50041.1 - 0.001 18.9 8.1 0.42 10.6 0.0 5.9 7 0 0 7 7 6 1 Tetratricopeptide repeat MerR_2 PF13591.1 CCF50041.1 - 0.051 13.1 0.2 0.2 11.2 0.1 2.0 2 0 0 2 2 2 0 MerR HTH family regulatory protein TPR_4 PF07721.9 CCF50041.1 - 0.056 13.8 22.2 0.55 10.8 0.6 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 CCF50041.1 - 0.21 11.6 3.0 15 5.8 0.1 5.1 6 0 0 6 6 6 0 PPR repeat Homeobox PF00046.24 CCF50042.1 - 2e-07 30.5 3.1 1.5e-06 27.7 2.2 2.3 1 1 0 1 1 1 1 Homeobox domain Ustilago_mating PF05722.7 CCF50043.1 - 1.2e-186 618.7 7.4 1.7e-186 618.2 5.1 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein Homeobox_KN PF05920.6 CCF50043.1 - 9.5e-16 57.2 1.6 1e-14 53.9 0.2 2.9 2 1 0 2 2 2 1 Homeobox KN domain Sas10_Utp3 PF04000.10 CCF50044.1 - 1.2e-22 79.9 0.5 1.2e-22 79.9 0.4 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Uds1 PF15456.1 CCF50046.1 - 2.5e-20 72.6 6.7 2.5e-20 72.6 4.6 9.3 5 1 5 10 10 10 1 Up-regulated During Septation KxDL PF10241.4 CCF50046.1 - 0.031 14.1 0.3 0.031 14.1 0.2 6.3 7 0 0 7 7 7 0 Uncharacterized conserved protein NYD-SP28_assoc PF14775.1 CCF50046.1 - 0.35 10.6 10.6 0.52 10.0 1.2 3.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain COPIIcoated_ERV PF07970.7 CCF50047.1 - 1.3e-69 234.2 0.0 2.1e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCF50047.1 - 5.3e-33 112.8 0.3 1.2e-32 111.6 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ACOX PF01756.14 CCF50048.1 - 3e-47 160.4 0.0 4.9e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CCF50048.1 - 1.1e-13 50.4 0.9 3.6e-13 48.7 0.3 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCF50048.1 - 1.4e-10 41.5 0.1 6.7e-10 39.3 0.0 2.2 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CCF50048.1 - 1.6e-07 31.5 0.7 2.6e-06 27.6 0.7 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_43 PF04616.9 CCF50049.1 - 3.1e-33 115.1 0.0 3.6e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CTP_transf_1 PF01148.15 CCF50050.1 - 1.5e-16 60.8 2.0 3.8e-12 46.4 0.7 3.1 1 1 1 2 2 2 2 Cytidylyltransferase family DNA_Packaging_2 PF11123.3 CCF50051.1 - 0.022 14.6 0.1 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 DNA packaging protein Semialdhyde_dhC PF02774.13 CCF50052.1 - 2.6e-44 151.2 0.0 4e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCF50052.1 - 2.2e-27 95.7 0.0 4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCF50052.1 - 0.0026 17.6 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 CCF50052.1 - 0.022 14.2 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.11 CCF50052.1 - 0.05 14.1 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Hira PF07569.6 CCF50053.1 - 4.4e-53 179.7 0.0 1.2e-52 178.3 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 CCF50053.1 - 1.7e-41 138.5 23.0 3.8e-10 39.2 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 CCF50053.1 - 4.3e-10 38.8 0.6 1.2e-09 37.4 0.4 1.8 1 0 0 1 1 1 1 HIRA B motif Nup160 PF11715.3 CCF50053.1 - 0.0025 16.0 1.9 0.046 11.8 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 CCF50053.1 - 0.018 14.7 1.2 2.2 8.0 0.1 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Choline_kinase PF01633.15 CCF50054.1 - 2.2e-34 118.9 0.0 2.7e-22 79.4 0.0 2.8 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 CCF50054.1 - 2.3e-05 24.2 0.5 0.011 15.4 0.0 3.0 3 1 0 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 CCF50055.1 - 2e-74 250.0 0.0 2.5e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50055.1 - 5.9e-32 110.7 0.0 8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50055.1 - 7.5e-05 21.8 0.0 0.016 14.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCF50055.1 - 0.023 14.4 0.9 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CoaE PF01121.15 CCF50056.1 - 1.5e-53 180.8 0.0 1.9e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CCF50056.1 - 0.00035 21.3 0.1 0.003 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF50056.1 - 0.00085 19.6 0.3 0.011 16.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain UBX PF00789.15 CCF50057.1 - 2.8e-05 24.0 0.0 8.7e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 UBX domain DUF3323 PF11796.3 CCF50057.1 - 0.032 13.5 11.3 0.065 12.5 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF572 PF04502.8 CCF50057.1 - 0.12 11.5 14.2 0.18 10.9 9.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2_2 PF12756.2 CCF50057.1 - 0.19 11.8 1.2 0.44 10.6 0.0 2.0 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Hex_IIIa PF02455.11 CCF50057.1 - 2.9 6.4 6.7 3.9 6.0 4.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Orbi_VP5 PF00901.12 CCF50057.1 - 9.2 4.3 14.9 13 3.8 10.3 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Tubulin_3 PF14881.1 CCF50058.1 - 5.7e-28 97.5 0.1 1.9e-27 95.9 0.1 1.8 1 1 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCF50058.1 - 1.8e-27 95.6 0.8 6.3e-27 93.9 0.5 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CCF50058.1 - 0.00012 21.9 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain F-box-like PF12937.2 CCF50059.1 - 1.1e-06 28.2 0.3 0.033 13.8 0.0 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 CCF50059.1 - 0.00021 20.8 4.4 0.14 11.8 0.2 2.4 2 0 0 2 2 2 2 F-box domain TPR_11 PF13414.1 CCF50059.1 - 0.022 14.4 0.5 0.058 13.0 0.3 1.7 1 0 0 1 1 1 0 TPR repeat MIT PF04212.13 CCF50059.1 - 0.034 14.0 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF805 PF05656.9 CCF50060.1 - 0.054 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Response_reg PF00072.19 CCF50061.1 - 1e-17 64.1 0.0 3.1e-17 62.6 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 CCF50061.1 - 2.5e-15 56.1 0.0 5e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 CCF50061.1 - 8.4e-05 22.4 1.4 0.0004 20.3 0.9 2.2 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain eIF3_subunit PF08597.5 CCF50062.1 - 4.1e-53 180.4 26.4 4.6e-53 180.3 18.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit S1FA PF04689.8 CCF50062.1 - 0.015 15.1 1.3 1 9.3 0.8 2.8 2 0 0 2 2 2 0 DNA binding protein S1FA rRNA_processing PF08524.6 CCF50062.1 - 8.6 6.1 18.9 0.64 9.7 9.1 1.9 2 0 0 2 2 2 0 rRNA processing zf-H2C2_2 PF13465.1 CCF50063.1 - 3.8e-09 36.3 17.4 1.2e-05 25.3 3.6 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCF50063.1 - 1.5e-06 28.1 19.0 0.0014 18.8 1.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF50063.1 - 0.00051 20.1 16.7 0.014 15.7 0.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger PASTA PF03793.14 CCF50064.1 - 0.058 13.0 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 PASTA domain tRNA_m1G_MT PF01746.16 CCF50065.1 - 2.5e-25 89.1 0.0 7.8e-20 71.2 0.0 2.7 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF2036 PF09724.4 CCF50066.1 - 9e-55 186.0 0.0 1.1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) bZIP_1 PF00170.16 CCF50068.1 - 2.3e-05 24.2 13.7 2.3e-05 24.2 9.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor Ldh_1_N PF00056.18 CCF50069.1 - 2.8e-46 156.8 0.5 4.2e-46 156.2 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCF50069.1 - 3e-42 144.3 0.0 4.8e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CCF50069.1 - 0.006 15.9 0.1 0.25 10.6 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CCF50069.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 CCF50069.1 - 0.025 13.6 1.5 0.37 9.8 0.2 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aldo_ket_red PF00248.16 CCF50071.1 - 2.1e-56 190.8 0.0 2.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Na_Ca_ex PF01699.19 CCF50072.1 - 5.9e-45 152.3 28.2 8.4e-25 87.0 5.5 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Complex1_49kDa PF00346.14 CCF50073.1 - 4.1e-127 422.8 0.0 5.6e-127 422.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 CCF50073.1 - 0.024 13.3 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Pkinase PF00069.20 CCF50074.1 - 2.2e-70 236.7 0.0 3.2e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50074.1 - 5e-35 120.8 0.0 8e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50074.1 - 0.0029 16.6 0.0 0.0063 15.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Asp PF00026.18 CCF50075.1 - 1.9e-106 355.9 0.2 2.3e-106 355.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF50075.1 - 7.7e-10 38.9 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCF50075.1 - 2.8e-05 23.7 0.0 0.00037 20.0 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCF50075.1 - 3.2e-05 24.3 0.1 0.025 15.0 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Homeobox PF00046.24 CCF50077.1 - 3.8e-19 68.0 4.8 7.1e-19 67.1 3.3 1.5 1 0 0 1 1 1 1 Homeobox domain G6PD_C PF02781.11 CCF50078.1 - 5.2e-124 412.8 0.0 6.9e-124 412.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCF50078.1 - 2.4e-61 207.1 0.0 4.2e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Rad4 PF03835.10 CCF50079.1 - 4.8e-28 97.3 0.2 4.8e-28 97.3 0.1 2.6 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CCF50079.1 - 5.9e-26 89.9 0.1 1.2e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CCF50079.1 - 3.9e-14 51.9 0.0 2.1e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCF50079.1 - 1.3e-12 47.7 0.2 1.3e-12 47.7 0.1 4.0 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCF50079.1 - 2.6e-08 34.0 0.1 5.1e-06 26.6 0.0 3.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily FAT PF02259.18 CCF50080.1 - 1.3e-70 238.1 7.0 1.3e-70 238.1 4.9 2.2 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 CCF50080.1 - 1.3e-23 83.6 0.0 4.1e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCF50080.1 - 0.0002 20.7 0.2 0.00064 19.1 0.1 1.9 1 0 0 1 1 1 1 FATC domain Med3 PF11593.3 CCF50080.1 - 0.00083 18.6 22.8 0.00083 18.6 15.8 5.2 5 0 0 5 5 5 3 Mediator complex subunit 3 fungal PI3_PI4_kinase PF00454.22 CCF50081.1 - 1.7e-32 112.8 0.0 2.7e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCF50081.1 - 1.4e-05 24.3 0.5 3.1e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.3 CCF50081.1 - 0.0062 16.2 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 CCDC84 PF14968.1 CCF50081.1 - 0.065 12.7 1.2 0.26 10.7 0.8 2.0 1 0 0 1 1 1 0 Coiled coil protein 84 OCD_Mu_crystall PF02423.10 CCF50082.1 - 7.8e-23 80.7 0.0 2.6e-20 72.4 0.0 2.3 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Rhabdo_M1 PF03342.8 CCF50083.1 - 0.009 15.1 1.7 0.013 14.6 1.2 1.2 1 0 0 1 1 1 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Snapin_Pallidin PF14712.1 CCF50083.1 - 0.051 13.8 8.0 0.95 9.8 4.6 2.6 2 1 0 2 2 2 0 Snapin/Pallidin IncA PF04156.9 CCF50083.1 - 0.1 12.2 10.2 12 5.4 7.1 2.3 1 1 0 1 1 1 0 IncA protein Syntaxin-6_N PF09177.6 CCF50083.1 - 1.1 9.7 6.6 3.6 8.0 0.9 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.10 CCF50083.1 - 2 7.9 7.2 0.99 8.9 1.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 CCF50083.1 - 9.5 6.3 8.3 38 4.3 5.6 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 CCF50084.1 - 1.6e-06 27.7 1.9 0.0031 17.3 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.6 CCF50084.1 - 0.047 12.8 0.3 0.65 9.1 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split Autophagy_act_C PF03987.10 CCF50085.1 - 5.4e-11 42.5 0.0 6.9e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain WD40 PF00400.27 CCF50087.1 - 9.1e-33 110.9 13.5 9.7e-08 31.6 0.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Pox_P4B PF03292.9 CCF50087.1 - 0.12 10.2 0.1 0.24 9.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus P4B major core protein CLTH PF10607.4 CCF50088.1 - 4.8e-22 78.2 0.2 1.7e-21 76.4 0.0 1.9 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCF50088.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 LisH NADH-G_4Fe-4S_3 PF10588.4 CCF50088.1 - 0.072 12.3 0.6 0.94 8.7 0.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NIF PF03031.13 CCF50089.1 - 4.4e-10 39.4 0.0 0.011 15.3 0.0 3.4 3 0 0 3 3 3 3 NLI interacting factor-like phosphatase Vma12 PF11712.3 CCF50090.1 - 0.0012 18.6 1.4 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-RING_5 PF14634.1 CCF50091.1 - 9.5e-06 25.2 6.3 9.5e-06 25.2 4.3 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCF50091.1 - 3.6e-05 23.5 12.7 3.6e-05 23.5 8.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF50091.1 - 0.00035 20.5 7.8 0.00035 20.5 5.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF50091.1 - 0.00074 19.1 12.0 0.00074 19.1 8.3 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF50091.1 - 0.034 13.8 7.0 0.088 12.5 4.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Arginase PF00491.16 CCF50092.1 - 8.8e-80 267.9 0.0 1e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family DEAD PF00270.24 CCF50093.1 - 2.6e-37 127.9 0.1 5.7e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF50093.1 - 6.9e-25 86.7 0.0 1.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF50093.1 - 8.2e-07 29.0 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCF50093.1 - 0.0033 16.5 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Methyltransf_18 PF12847.2 CCF50094.1 - 1.3e-06 28.9 0.0 2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF50094.1 - 9.9e-06 25.3 0.0 0.0062 16.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CCF50094.1 - 2.9e-05 23.7 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF50094.1 - 5.2e-05 23.6 0.0 0.00018 21.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF50094.1 - 0.00033 21.0 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF50094.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ribosomal_S26e PF01283.14 CCF50096.1 - 1e-52 177.1 6.0 1.2e-52 176.9 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 CCF50096.1 - 0.14 11.4 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Sgf11 PF08209.6 CCF50096.1 - 0.19 11.0 0.3 0.19 11.0 0.2 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.1 CCF50096.1 - 0.31 10.2 1.9 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain PHD_2 PF13831.1 CCF50096.1 - 2.2 7.6 7.6 6.8 6.1 2.6 2.2 2 0 0 2 2 2 0 PHD-finger Microvir_J PF04726.8 CCF50096.1 - 3.9 7.5 5.5 19 5.3 3.4 2.1 2 0 0 2 2 2 0 Microvirus J protein CPSF_A PF03178.10 CCF50097.1 - 8.2e-52 176.2 0.0 8.2e-51 172.9 0.0 2.6 3 1 0 3 3 3 1 CPSF A subunit region AIF_C PF14721.1 CCF50097.1 - 0.69 10.1 3.2 1.6 9.0 2.2 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDHD PF02862.12 CCF50097.1 - 5.2 6.8 6.9 11 5.6 4.7 1.5 1 0 0 1 1 1 0 DDHD domain WW PF00397.21 CCF50098.1 - 1.1e-09 37.9 1.5 2.4e-09 36.8 1.0 1.6 1 0 0 1 1 1 1 WW domain Alg14 PF08660.6 CCF50099.1 - 4.4e-46 156.9 0.0 6.5e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like YvrJ PF12841.2 CCF50099.1 - 0.67 9.2 4.3 0.68 9.2 0.3 2.3 2 0 0 2 2 2 0 YvrJ protein family LON PF02190.11 CCF50100.1 - 3e-20 72.8 0.0 1.8e-18 66.9 0.0 2.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 CCF50100.1 - 2.9e-14 52.8 20.5 5.4e-09 35.9 5.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF50100.1 - 3.7e-12 45.7 13.5 9.4e-08 31.6 3.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF50100.1 - 1.1e-11 44.4 21.9 4.7e-07 29.5 6.6 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 CCF50100.1 - 4.3e-11 42.2 18.6 9.9e-06 25.1 5.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF50100.1 - 2.1e-10 40.1 18.5 4.3e-06 26.3 5.1 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCF50100.1 - 1.3e-08 34.5 29.2 2.5e-06 27.2 3.1 2.9 3 0 0 3 3 2 2 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CCF50100.1 - 0.0013 18.2 2.7 0.0013 18.2 1.9 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CCF50100.1 - 0.013 15.2 18.6 0.47 10.2 2.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 CCF50100.1 - 0.95 9.6 11.3 0.26 11.4 2.6 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-P11 PF03854.9 CCF50100.1 - 1.5 8.3 11.5 0.68 9.4 4.9 2.5 2 0 0 2 2 2 0 P-11 zinc finger Glutaredoxin PF00462.19 CCF50101.1 - 1.7e-16 59.9 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 CCF50101.1 - 0.0091 16.1 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 CCF50101.1 - 0.014 15.6 0.1 0.018 15.2 0.1 1.3 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 CCF50101.1 - 0.037 13.8 0.1 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin domain DUF953 PF06110.6 CCF50101.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.15 CCF50101.1 - 0.11 11.9 0.2 0.19 11.2 0.1 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain GBP_C PF02841.9 CCF50103.1 - 0.097 11.8 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Pkinase PF00069.20 CCF50104.1 - 3.9e-68 229.4 0.0 5.3e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50104.1 - 1.6e-27 96.2 0.1 5.1e-27 94.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Slu7 PF11708.3 CCF50105.1 - 2.8e-74 249.8 18.4 2.8e-74 249.8 12.8 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 CCF50105.1 - 0.061 13.0 0.9 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Pro_CA PF00484.14 CCF50105.1 - 3.3 7.7 6.3 3 7.8 0.0 3.2 4 0 0 4 4 4 0 Carbonic anhydrase RRM_1 PF00076.17 CCF50106.1 - 0.00026 20.5 0.0 0.0077 15.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50106.1 - 0.00033 20.5 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MAD PF05557.8 CCF50107.1 - 7.4e-30 103.7 60.9 3.7e-28 98.0 42.2 2.9 1 1 0 1 1 1 1 Mitotic checkpoint protein TMF_DNA_bd PF12329.3 CCF50107.1 - 0.0042 16.8 2.7 0.0042 16.8 1.9 9.1 7 3 3 10 10 10 3 TATA element modulatory factor 1 DNA binding CVNH PF08881.5 CCF50107.1 - 0.014 15.6 0.5 1.8 8.8 0.0 3.8 3 1 0 3 3 3 0 CVNH domain INCA1 PF15142.1 CCF50107.1 - 0.021 14.6 0.1 0.055 13.2 0.1 1.7 1 0 0 1 1 1 0 INCA1 Tropomyosin_1 PF12718.2 CCF50107.1 - 0.079 12.8 66.3 0.019 14.7 11.6 6.1 4 2 2 6 6 6 0 Tropomyosin like FlaC_arch PF05377.6 CCF50107.1 - 0.39 10.6 6.8 7.8 6.4 0.1 5.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.14 CCF50107.1 - 9 3.8 60.0 0.069 10.8 5.1 3.7 2 1 1 3 3 3 0 Myosin tail BTB_2 PF02214.17 CCF50108.1 - 0.00066 19.8 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Pkinase PF00069.20 CCF50109.1 - 3.8e-61 206.5 3.4 3.6e-41 141.0 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50109.1 - 1.4e-23 83.2 8.7 1.4e-19 70.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF50109.1 - 0.00011 21.2 0.0 0.00011 21.2 0.0 2.6 3 1 0 3 3 3 1 Kinase-like CytochromB561_N PF09786.4 CCF50109.1 - 0.0093 14.4 14.8 0.013 13.9 10.3 1.3 1 0 0 1 1 1 1 Cytochrome B561, N terminal Pkinase_C PF00433.19 CCF50109.1 - 0.035 14.6 0.1 0.12 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 CCF50109.1 - 0.06 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CCF50109.1 - 0.15 10.8 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med15 PF09606.5 CCF50109.1 - 2.4 6.2 88.8 3.4 5.7 61.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GMC_oxred_N PF00732.14 CCF50110.1 - 4.4e-65 219.7 0.0 6.7e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF50110.1 - 1.1e-36 126.3 0.0 2e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCF50110.1 - 8.5e-06 24.8 0.7 0.014 14.2 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCF50110.1 - 7.1e-05 22.7 1.1 0.00014 21.8 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF50110.1 - 9.3e-05 21.4 0.3 0.00058 18.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCF50110.1 - 9.4e-05 21.4 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCF50110.1 - 0.0003 20.9 0.1 0.95 9.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF50110.1 - 0.0091 15.8 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF50110.1 - 0.018 14.8 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCF50110.1 - 0.035 12.5 0.2 0.55 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CCF50110.1 - 0.06 12.4 0.3 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 CCF50110.1 - 0.079 11.9 0.9 0.12 11.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain ChAPs PF09295.5 CCF50111.1 - 9.8e-155 515.1 0.0 1.7e-154 514.3 0.0 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CCF50111.1 - 2.5e-06 27.7 3.0 8.9e-05 22.7 0.3 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF50111.1 - 1.1e-05 24.9 2.8 0.01 15.4 0.1 3.9 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CCF50111.1 - 0.00053 19.6 4.3 2 8.5 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CCF50111.1 - 0.0026 17.8 6.7 1 9.5 0.1 3.8 2 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCF50111.1 - 0.028 14.8 1.6 68 4.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF50111.1 - 0.043 14.4 5.9 65 4.5 0.0 6.1 4 1 2 6 6 6 0 Tetratricopeptide repeat Ribosom_S12_S23 PF00164.20 CCF50112.1 - 1.8e-46 156.5 1.6 2.1e-46 156.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.1 CCF50113.1 - 1.2e-47 161.8 1.8 2e-47 161.1 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCF50113.1 - 0.028 14.5 0.9 4.7 7.4 0.1 3.9 3 1 0 3 3 3 0 PH domain IPK PF03770.11 CCF50114.1 - 2.2e-40 138.4 0.0 3.7e-39 134.4 0.0 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase TPR_11 PF13414.1 CCF50115.1 - 3.4e-08 33.0 4.2 6.6e-05 22.4 1.7 3.0 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.1 CCF50115.1 - 8.9e-05 23.0 2.6 0.0062 17.1 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCF50115.1 - 0.00023 20.6 1.0 0.0037 16.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50115.1 - 0.0013 18.5 2.2 0.026 14.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF50115.1 - 0.0017 18.8 1.4 0.02 15.5 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCF50115.1 - 0.011 15.4 0.4 0.084 12.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCF50115.1 - 0.019 15.1 0.7 3.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat L27_2 PF09045.5 CCF50115.1 - 0.029 13.9 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 L27_2 TPR_12 PF13424.1 CCF50115.1 - 0.036 14.0 0.7 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Endotoxin_N PF03945.9 CCF50115.1 - 0.041 13.2 0.1 0.17 11.2 0.0 1.9 3 0 0 3 3 3 0 delta endotoxin, N-terminal domain FadA PF09403.5 CCF50115.1 - 0.11 12.5 0.9 2.5 8.1 0.0 2.9 3 1 0 3 3 3 0 Adhesion protein FadA Inhibitor_Mig-6 PF11555.3 CCF50115.1 - 0.23 11.9 2.2 2.3 8.6 1.5 2.3 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Ank PF00023.25 CCF50116.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat SRP14 PF02290.10 CCF50117.1 - 1.9e-23 82.2 2.1 2.9e-23 81.5 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle 14kD protein AAA_18 PF13238.1 CCF50117.1 - 0.075 13.3 0.2 0.22 11.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain RelB_N PF12910.2 CCF50117.1 - 0.21 10.9 1.1 7.9 5.9 0.1 2.7 3 0 0 3 3 3 0 Antitoxin of toxin-antitoxin stability system N-terminal Rota_VP2 PF05087.7 CCF50117.1 - 1.4 6.7 5.9 1.7 6.4 4.1 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein DUF726 PF05277.7 CCF50118.1 - 3.7e-115 384.4 2.5 5.1e-115 384.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 CCF50118.1 - 0.0002 21.1 1.5 0.0011 18.7 0.1 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2203 PF09969.4 CCF50118.1 - 8.2 6.6 6.4 9.2 6.5 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Transketolase_N PF00456.16 CCF50119.1 - 4.7e-148 492.4 0.1 6.2e-148 492.0 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCF50119.1 - 1.7e-40 138.3 0.1 4.3e-40 137.0 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCF50119.1 - 9.5e-13 48.1 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCF50119.1 - 0.0024 16.8 0.2 0.061 12.2 0.1 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RVT_2 PF07727.9 CCF50125.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_clus PF00172.13 CCF50126.1 - 0.0067 16.3 9.5 0.019 14.8 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LigB PF02900.13 CCF50127.1 - 2.9e-31 108.4 0.3 1.1e-30 106.5 0.2 1.7 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase CoA_binding_2 PF13380.1 CCF50127.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain ABC1 PF03109.11 CCF50128.1 - 1.6e-31 108.7 0.1 3.2e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCF50128.1 - 0.014 14.7 0.0 0.039 13.2 0.0 1.8 1 1 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 CCF50129.1 - 1.6e-45 155.4 23.4 1.6e-45 155.4 16.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF50129.1 - 2e-16 59.6 16.3 5.3e-16 58.2 11.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CCF50129.1 - 0.0012 16.9 3.7 0.06 11.3 2.1 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family A2M_comp PF07678.9 CCF50129.1 - 0.13 11.5 0.5 0.22 10.7 0.4 1.3 1 0 0 1 1 1 0 A-macroglobulin complement component FAD_binding_2 PF00890.19 CCF50130.1 - 2.1e-87 293.7 0.2 3e-87 293.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CCF50130.1 - 4.5e-21 74.4 0.3 1.7e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CCF50130.1 - 1.7e-14 53.5 0.6 9.9e-14 50.9 0.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCF50130.1 - 5.4e-11 42.7 0.0 5.1e-09 36.3 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF50130.1 - 6.1e-11 42.1 0.3 7e-10 38.7 0.0 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCF50130.1 - 5.8e-09 35.5 0.3 1.4e-08 34.3 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF50130.1 - 2.6e-07 29.4 3.0 7.9e-05 21.3 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CCF50130.1 - 5.1e-07 29.0 0.6 0.001 18.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CCF50130.1 - 1.2e-06 27.6 1.9 0.0031 16.4 0.2 3.2 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCF50130.1 - 3.5e-06 26.3 2.1 1.6e-05 24.1 1.4 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCF50130.1 - 4.8e-05 23.5 1.1 8.3e-05 22.7 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCF50130.1 - 7.7e-05 21.9 0.0 0.003 16.7 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CCF50130.1 - 0.0011 19.2 2.5 0.0046 17.3 0.1 3.0 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF50130.1 - 0.012 15.4 0.2 0.12 12.1 0.2 2.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 CCF50130.1 - 0.017 14.7 0.3 0.044 13.3 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CCF50130.1 - 0.023 13.6 0.3 0.045 12.6 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 CCF50130.1 - 0.024 14.8 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding GDI PF00996.13 CCF50130.1 - 0.024 12.9 0.0 0.041 12.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor TrkA_N PF02254.13 CCF50130.1 - 0.12 12.3 0.1 0.46 10.4 0.0 2.1 2 0 0 2 2 1 0 TrkA-N domain Nfu_N PF08712.6 CCF50131.1 - 8.4e-33 111.8 0.0 2.1e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CCF50131.1 - 9.2e-22 76.6 0.1 1.9e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain ECH PF00378.15 CCF50132.1 - 3.4e-78 262.1 2.3 4.3e-78 261.8 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CCF50132.1 - 0.0016 18.2 0.8 0.027 14.2 0.0 2.6 2 1 1 3 3 3 1 Peptidase family S49 ECH_C PF13766.1 CCF50132.1 - 0.08 13.0 1.4 0.4 10.8 0.2 2.1 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region RVT_2 PF07727.9 CCF50134.1 - 1.3e-15 57.0 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_B11R PF07033.6 CCF50134.1 - 0.0053 16.2 0.1 0.0087 15.5 0.1 1.3 1 0 0 1 1 1 1 Orthopoxvirus B11R protein Spc97_Spc98 PF04130.8 CCF50137.1 - 3.4e-56 190.6 0.0 3e-55 187.5 0.0 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family Stn1_C PF12659.2 CCF50137.1 - 0.11 12.3 0.7 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH DNA_pol_E_B PF04042.11 CCF50138.1 - 8.1e-44 149.3 0.0 1.2e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF572 PF04502.8 CCF50140.1 - 2.4e-80 270.1 5.1 3.8e-80 269.5 3.6 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) Benyvirus_14KDa PF07255.6 CCF50140.1 - 0.08 12.8 0.2 0.38 10.6 0.1 1.9 1 1 1 2 2 2 0 Benyvirus 14KDa protein YqzM PF14141.1 CCF50141.1 - 0.12 12.1 0.8 0.25 11.1 0.5 1.5 1 0 0 1 1 1 0 YqzM-like protein CRAL_TRIO PF00650.15 CCF50142.1 - 4e-40 136.9 0.0 7.2e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Hydrolase_6 PF13344.1 CCF50142.1 - 1.2e-28 98.9 0.0 2.5e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF50142.1 - 2.7e-18 65.4 0.0 7.9e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCF50142.1 - 6.2e-14 52.9 0.0 8.2e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CRAL_TRIO_2 PF13716.1 CCF50142.1 - 8.8e-14 51.6 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HAD_2 PF13419.1 CCF50142.1 - 3.4e-06 27.3 0.1 0.021 15.0 0.0 2.9 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase CRAL_TRIO_N PF03765.10 CCF50142.1 - 0.00011 22.2 0.1 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peripla_BP_4 PF13407.1 CCF50142.1 - 0.0073 15.6 0.0 0.02 14.2 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein domain PGP_phosphatase PF09419.5 CCF50142.1 - 0.098 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase CMD PF02627.15 CCF50144.1 - 9.2e-09 35.0 0.2 1.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Mito_carr PF00153.22 CCF50145.1 - 1.8e-53 178.2 5.1 3.6e-18 65.0 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein PGM_PMM_I PF02878.11 CCF50146.1 - 1.6e-18 66.5 0.1 6.7e-09 35.3 0.0 2.9 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCF50146.1 - 5.3e-13 49.2 0.0 2.2e-12 47.2 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCF50146.1 - 2.7e-08 33.6 0.0 6.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CCF50146.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ORMDL PF04061.9 CCF50147.1 - 6.2e-57 190.9 2.1 7.5e-57 190.6 1.5 1.1 1 0 0 1 1 1 1 ORMDL family DUF663 PF04950.7 CCF50148.1 - 1.3e-88 296.8 0.0 2.2e-88 296.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCF50148.1 - 9.4e-22 76.3 0.0 1.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain eIF_4EBP PF05456.6 CCF50149.1 - 8.5e-06 25.4 0.3 9.2e-06 25.3 0.2 1.2 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Secretin_N_2 PF07655.8 CCF50149.1 - 0.56 10.6 5.3 1 9.7 3.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Mito_carr PF00153.22 CCF50150.1 - 1.3e-65 217.0 1.4 4.2e-25 87.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad52_Rad22 PF04098.10 CCF50151.1 - 5e-57 191.9 0.1 4.1e-56 188.9 0.0 2.5 3 0 0 3 3 3 1 Rad52/22 family double-strand break repair protein Trehalase PF01204.13 CCF50151.1 - 0.78 8.3 4.5 0.15 10.6 0.2 1.8 2 0 0 2 2 2 0 Trehalase Pkinase PF00069.20 CCF50152.1 - 5.3e-69 232.2 0.0 8.9e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50152.1 - 2.2e-37 128.5 0.0 6.6e-37 126.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50152.1 - 1.1e-07 31.1 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 CCF50152.1 - 0.002 17.5 0.1 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 CCF50152.1 - 0.0061 15.9 0.3 0.014 14.7 0.2 1.6 1 0 0 1 1 1 1 RIO1 family DUF1687 PF07955.6 CCF50153.1 - 1.4e-06 28.3 4.8 0.027 14.4 1.3 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1687) F-box PF00646.28 CCF50154.1 - 2.3e-08 33.4 0.9 6e-08 32.1 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCF50154.1 - 7.9e-06 25.4 0.4 2.2e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like MNSV_P7B PF06692.6 CCF50154.1 - 0.024 14.4 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein DDOST_48kD PF03345.9 CCF50155.1 - 2.2e-98 329.5 0.6 1.2e-60 205.2 0.1 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta ABC_transp_aux PF09822.4 CCF50155.1 - 0.0017 17.8 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system Gly_radical PF01228.16 CCF50155.1 - 0.003 17.9 0.0 0.0078 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycine radical SynMuv_product PF06047.6 CCF50156.1 - 3.6e-51 171.3 1.5 3.6e-51 171.3 1.0 2.2 2 0 0 2 2 2 1 Ras-induced vulval development antagonist ATP_bind_4 PF01902.12 CCF50157.1 - 8.7e-37 126.6 0.0 1.7e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 CCF50157.1 - 2e-16 59.8 0.0 1.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP SUV3_C PF12513.3 CCF50158.1 - 1.6e-15 56.2 0.3 3.6e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCF50158.1 - 1.3e-11 44.2 0.0 2.9e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LrgB PF04172.11 CCF50159.1 - 4.4e-18 65.2 11.5 4.1e-16 58.7 1.0 3.5 3 1 0 3 3 3 2 LrgB-like family LrgA PF03788.9 CCF50159.1 - 0.00082 19.0 2.5 0.00082 19.0 1.7 2.9 3 0 0 3 3 3 1 LrgA family TMEM154 PF15102.1 CCF50159.1 - 0.091 12.4 1.5 0.55 9.9 0.1 2.7 2 0 0 2 2 2 0 TMEM154 protein family TMCO5 PF14992.1 CCF50159.1 - 0.091 11.8 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 TMCO5 family DUF3043 PF11241.3 CCF50159.1 - 0.41 10.2 4.2 0.47 10.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Fig1 PF12351.3 CCF50159.1 - 0.52 10.1 5.6 0.41 10.5 0.3 2.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Zn_clus PF00172.13 CCF50160.1 - 0.015 15.1 10.7 0.035 14.0 7.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.6 CCF50160.1 - 0.74 8.1 3.3 1.2 7.3 2.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus LCM PF04072.9 CCF50161.1 - 1.5e-16 60.4 0.0 5.5e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Glyco_transf_11 PF01531.11 CCF50162.1 - 0.13 11.2 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Hydrophobin PF01185.13 CCF50163.1 - 4e-18 65.6 13.3 5.2e-18 65.2 9.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 CCF50163.1 - 1.3 9.5 7.8 2 8.9 0.5 2.5 2 0 0 2 2 2 0 Ion channel inhibitory toxin Toxin_9 PF02819.10 CCF50163.1 - 2 8.5 8.5 5.1 7.2 0.6 2.3 2 0 0 2 2 2 0 Spider toxin Ribosomal_L28e PF01778.12 CCF50164.1 - 3.2e-37 127.4 0.6 4.1e-37 127.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family WD40 PF00400.27 CCF50165.1 - 5.2e-09 35.6 0.9 0.026 14.4 0.2 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 CCF50165.1 - 1e-08 34.7 0.1 2.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF50165.1 - 0.00026 20.5 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain B-block_TFIIIC PF04182.7 CCF50166.1 - 1e-11 44.5 0.0 4.2e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 CCF50166.1 - 0.00067 19.2 0.1 0.0034 17.0 0.0 2.3 1 0 0 1 1 1 1 MarR family MarR PF01047.17 CCF50166.1 - 0.0029 17.2 0.0 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 MarR family HTH_27 PF13463.1 CCF50166.1 - 0.014 15.7 0.3 0.23 11.8 0.0 3.3 3 0 0 3 3 3 0 Winged helix DNA-binding domain Ribosomal_S17 PF00366.15 CCF50167.1 - 8.5e-17 60.9 0.4 1.2e-16 60.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Scs3p PF10261.4 CCF50169.1 - 9.7e-60 201.5 0.3 1.2e-59 201.2 0.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ApoO PF09769.4 CCF50170.1 - 2.1e-32 112.0 0.2 4.5e-32 110.9 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O Apolipoprotein PF01442.13 CCF50170.1 - 0.016 14.6 1.1 0.62 9.5 0.3 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Tox-REase-9 PF15650.1 CCF50170.1 - 0.038 14.2 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 bZIP_1 PF00170.16 CCF50171.1 - 0.0033 17.3 7.1 0.51 10.3 0.5 2.6 2 0 0 2 2 2 2 bZIP transcription factor Rootletin PF15035.1 CCF50171.1 - 0.01 15.8 2.5 0.01 15.8 1.8 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4470 PF14737.1 CCF50171.1 - 0.093 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) bZIP_2 PF07716.10 CCF50171.1 - 0.26 11.1 7.7 2.6 7.9 0.6 2.6 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 CCF50171.1 - 0.28 10.7 8.5 0.18 11.3 1.6 2.4 2 0 0 2 2 2 0 IncA protein FlaC_arch PF05377.6 CCF50171.1 - 0.52 10.2 2.3 6.6 6.7 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NYD-SP28_assoc PF14775.1 CCF50171.1 - 0.94 9.2 7.3 7.2 6.3 0.9 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 CCF50171.1 - 1.2 8.9 4.6 5.6 6.7 0.3 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Flavodoxin_2 PF02525.12 CCF50172.1 - 0.15 11.5 1.2 0.33 10.4 0.8 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold DUF1043 PF06295.7 CCF50172.1 - 1.6 8.4 7.6 0.65 9.6 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) PAP_assoc PF03828.14 CCF50173.1 - 5.4e-15 55.0 0.1 1.1e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CCF50173.1 - 1.6e-05 25.1 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 CCF50173.1 - 0.023 13.4 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Poly(A) polymerase central domain RVT_2 PF07727.9 CCF50174.1 - 0.069 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 CCF50175.1 - 4.3e-52 176.8 0.0 6.1e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50175.1 - 2.8e-36 124.9 0.0 4.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50175.1 - 0.00051 19.0 0.0 0.0022 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CCF50175.1 - 1.3 7.8 0.1 1.9 7.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 FAM75 PF14650.1 CCF50177.1 - 0.055 12.8 0.1 0.064 12.6 0.1 1.0 1 0 0 1 1 1 0 FAM75 family UBA_4 PF14555.1 CCF50178.1 - 1.5e-10 40.4 0.3 4.4e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 CCF50178.1 - 1.4e-07 30.4 6.7 0.0041 16.5 0.2 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif UBA PF00627.26 CCF50178.1 - 0.002 17.9 0.2 0.046 13.5 0.0 3.1 3 0 0 3 3 3 1 UBA/TS-N domain UCH PF00443.24 CCF50178.1 - 0.0029 16.7 0.0 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase FRG1 PF06229.7 CCF50178.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 FRG1-like family S4 PF01479.20 CCF50179.1 - 1e-10 40.8 0.0 1.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain SAPS PF04499.10 CCF50179.1 - 0.025 13.2 1.1 0.034 12.8 0.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.4 CCF50179.1 - 0.044 12.4 14.5 0.067 11.8 10.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein S4_2 PF13275.1 CCF50179.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 S4 domain Hid1 PF12722.2 CCF50179.1 - 0.3 8.7 6.2 0.43 8.2 4.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2146 PF10220.4 CCF50179.1 - 0.8 7.6 6.0 1.1 7.1 4.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DDHD PF02862.12 CCF50179.1 - 5.8 6.6 10.7 15 5.3 7.4 1.6 1 0 0 1 1 1 0 DDHD domain PAP1 PF08601.5 CCF50179.1 - 6.9 6.2 18.1 0.15 11.6 7.9 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 S-AdoMet_synt_C PF02773.11 CCF50180.1 - 6.6e-74 246.1 0.4 1.2e-73 245.3 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCF50180.1 - 3.3e-48 162.5 0.0 7e-48 161.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCF50180.1 - 2.7e-44 149.4 0.2 2.7e-44 149.4 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ALS_ss_C PF10369.4 CCF50182.1 - 6.7e-23 80.2 0.0 7.4e-20 70.4 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 CCF50182.1 - 1.1e-11 43.9 0.0 2.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CCF50182.1 - 6.7e-08 32.2 0.0 3.1e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 ACT domain Pkinase PF00069.20 CCF50183.1 - 2.3e-58 197.3 0.0 2.2e-57 194.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50183.1 - 1.4e-27 96.3 0.0 1.1e-26 93.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCF50183.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.1 CCF50183.1 - 3.2e-05 23.7 0.0 0.00026 20.8 0.0 2.1 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 CCF50183.1 - 0.003 16.5 0.0 0.01 14.8 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCF50183.1 - 0.032 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 CCF50184.1 - 3e-128 428.2 22.8 3.5e-128 427.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF50184.1 - 1e-25 90.2 43.7 5.9e-20 71.2 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AflR PF08493.5 CCF50184.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Methyltransf_11 PF08241.7 CCF50185.1 - 0.00036 20.9 0.0 0.0061 17.0 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain gpW PF02831.10 CCF50185.1 - 0.039 13.4 0.1 0.69 9.4 0.0 3.0 2 1 0 2 2 2 0 gpW DUF3947 PF13135.1 CCF50185.1 - 0.08 13.1 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) WD40 PF00400.27 CCF50186.1 - 3e-16 58.5 8.3 6.9e-06 25.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat MADF_DNA_bdg PF10545.4 CCF50187.1 - 0.16 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Nop14 PF04147.7 CCF50187.1 - 0.31 8.8 36.4 0.023 12.6 21.9 1.5 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.7 CCF50187.1 - 0.65 9.2 31.3 1.3 8.1 21.7 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 CCF50187.1 - 1.6 6.6 21.0 4 5.3 14.5 1.6 1 0 0 1 1 1 0 CDC45-like protein AAA_12 PF13087.1 CCF50188.1 - 1.4e-43 148.5 0.0 2.3e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.6 CCF50188.1 - 1.5e-39 135.5 0.2 4.7e-18 65.2 0.0 3.3 3 0 0 3 3 3 3 DNA replication factor Dna2 AAA_11 PF13086.1 CCF50188.1 - 1.7e-39 135.8 0.0 1.2e-19 70.8 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CCF50188.1 - 1.7e-12 47.3 0.0 2.2e-11 43.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCF50188.1 - 2.2e-09 36.9 1.1 5.3e-08 32.5 0.1 3.1 2 1 1 3 3 3 1 Part of AAA domain Helicase_RecD PF05127.9 CCF50188.1 - 1.9e-05 24.4 0.0 0.00012 21.7 0.0 2.3 1 1 0 1 1 1 1 Helicase SRP54 PF00448.17 CCF50188.1 - 4.8e-05 22.8 0.1 8.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Cas_Cas4 PF01930.12 CCF50188.1 - 0.00042 20.2 1.0 0.0024 17.7 0.7 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 CCF50188.1 - 0.0013 18.2 0.5 1.7 8.0 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase CbiA PF01656.18 CCF50188.1 - 0.0037 16.6 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD-helicase PF00580.16 CCF50188.1 - 0.0051 16.1 0.1 0.011 15.0 0.1 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 CCF50188.1 - 0.0075 15.9 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCF50188.1 - 0.011 15.5 0.1 0.057 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.1 CCF50188.1 - 0.019 14.4 0.1 0.066 12.6 0.0 1.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF87 PF01935.12 CCF50188.1 - 0.094 12.5 0.3 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 FAD_binding_4 PF01565.18 CCF50189.1 - 3.7e-26 91.2 1.7 6e-26 90.5 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCF50189.1 - 1.5e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF1871 PF08958.5 CCF50189.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) mRNA_triPase PF02940.10 CCF50190.1 - 2.4e-48 164.7 0.1 2.8e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RVT_1 PF00078.22 CCF50191.1 - 6e-07 29.0 0.0 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CCF50191.1 - 0.014 15.1 0.6 0.033 13.8 0.1 1.8 2 0 0 2 2 2 0 Phage integrase family 2-Hacid_dh_C PF02826.14 CCF50192.1 - 8.1e-35 119.5 0.0 3.8e-34 117.3 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF50192.1 - 6.8e-17 61.1 0.0 1.1e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.1 CCF50192.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.12 CCF50192.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCF50192.1 - 0.053 13.3 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CDC45 PF02724.9 CCF50193.1 - 0.18 9.7 10.1 0.26 9.2 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PAP1 PF08601.5 CCF50193.1 - 0.67 9.5 33.9 1.1 8.8 23.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF605 PF04652.11 CCF50193.1 - 3.8 6.7 22.5 5.7 6.2 15.6 1.2 1 0 0 1 1 1 0 Vta1 like CytochromB561_N PF09786.4 CCF50193.1 - 5.7 5.2 25.4 8.5 4.6 17.6 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Cation_ATPase_C PF00689.16 CCF50194.1 - 2.1e-18 66.5 0.1 3e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF50194.1 - 4.7e-08 33.7 0.0 1.6e-07 32.0 0.0 1.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF50194.1 - 0.048 13.8 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ins_P5_2-kin PF06090.7 CCF50195.1 - 1.7e-55 188.3 0.0 2e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Cmc1 PF08583.5 CCF50196.1 - 6.3e-17 61.1 7.8 6.5e-17 61.0 5.0 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CCF50196.1 - 0.00039 20.4 3.0 0.14 12.2 0.2 2.2 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 Ndufs5 PF10200.4 CCF50196.1 - 0.051 13.5 0.6 0.081 12.9 0.3 1.5 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 CCF50196.1 - 0.36 10.8 4.5 13 5.8 1.2 2.4 2 0 0 2 2 2 0 CHCH domain Creb_binding PF09030.5 CCF50196.1 - 0.62 10.2 3.2 12 6.2 0.0 2.1 1 1 1 2 2 2 0 Creb binding DUF3128 PF11326.3 CCF50196.1 - 2.5 8.2 6.7 2.5 8.2 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) Ribosomal_S3Ae PF01015.13 CCF50197.1 - 1.6e-82 275.5 3.7 1.9e-82 275.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CCF50197.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S7e PF01251.13 CCF50198.1 - 2e-84 281.8 0.5 2.2e-84 281.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4174 PF13778.1 CCF50198.1 - 0.077 13.0 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) RasGAP PF00616.14 CCF50199.1 - 3.9e-26 91.9 0.0 1.3e-25 90.2 0.0 1.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Glyoxalase_3 PF13468.1 CCF50200.1 - 1.7e-24 86.6 0.0 1.9e-23 83.2 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCF50200.1 - 0.096 12.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Zn-ribbon_8 PF09723.5 CCF50201.1 - 8.2 6.4 7.6 54 3.8 5.3 2.1 1 1 1 2 2 2 0 Zinc ribbon domain TarH PF02203.10 CCF50203.1 - 0.00028 20.7 1.1 0.0004 20.2 0.6 1.4 1 1 0 1 1 1 1 Tar ligand binding domain homologue Lge1 PF11488.3 CCF50203.1 - 0.33 11.1 6.8 1.4 9.1 0.1 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 SPX PF03105.14 CCF50203.1 - 0.58 9.8 6.4 0.42 10.3 3.4 1.5 1 1 0 1 1 1 0 SPX domain DUF4085 PF13315.1 CCF50203.1 - 1.3 8.3 6.8 0.13 11.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) FlxA PF14282.1 CCF50203.1 - 1.9 8.4 6.2 0.17 11.8 0.9 1.7 2 0 0 2 2 2 0 FlxA-like protein DUF793 PF05633.6 CCF50203.1 - 1.9 7.1 6.8 1.9 7.1 3.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF793) Erp_C PF06780.6 CCF50203.1 - 5.4 6.8 11.1 2 8.2 1.7 2.2 2 0 0 2 2 2 0 Erp protein C-terminus APG6 PF04111.7 CCF50203.1 - 6 5.8 11.0 7.1 5.5 7.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF964 PF06133.6 CCF50203.1 - 8.2 6.5 9.2 9.7 6.2 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Transposase_22 PF02994.9 CCF50204.1 - 0.011 14.2 0.5 0.013 14.0 0.3 1.0 1 0 0 1 1 1 0 L1 transposable element Laminin_II PF06009.7 CCF50204.1 - 0.028 14.1 0.3 2.7 7.7 0.0 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.7 CCF50204.1 - 0.064 13.0 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Adaptin_binding PF10199.4 CCF50204.1 - 0.09 13.0 1.1 0.12 12.6 0.8 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Erp_C PF06780.6 CCF50204.1 - 0.094 12.5 0.4 0.11 12.3 0.3 1.1 1 0 0 1 1 1 0 Erp protein C-terminus NAM-associated PF14303.1 CCF50204.1 - 0.11 12.8 2.2 0.13 12.5 1.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GYF PF02213.11 CCF50205.1 - 0.00057 19.4 0.1 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 GYF domain Pox_polyA_pol_N PF12630.2 CCF50205.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain RCR PF12273.3 CCF50205.1 - 0.6 10.6 9.5 0.092 13.3 2.3 2.8 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Pex16 PF08610.5 CCF50205.1 - 1.9 7.3 8.4 0.15 11.0 1.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Pkinase PF00069.20 CCF50206.1 - 1.3e-63 214.5 0.0 2.3e-38 131.8 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50206.1 - 1.4e-36 125.9 0.0 4.9e-18 65.1 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 CCF50206.1 - 5.7e-16 58.4 0.1 5.7e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 CCF50206.1 - 3.2e-14 52.7 0.0 6.8e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 CCF50206.1 - 3.4e-11 42.8 1.6 1e-09 37.9 0.0 3.1 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Kinase-like PF14531.1 CCF50206.1 - 1.5e-05 24.0 0.0 0.016 14.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCF50206.1 - 0.0014 18.4 1.4 0.0076 16.0 0.0 3.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family DPBB_1 PF03330.13 CCF50207.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF4243 PF14027.1 CCF50208.1 - 3.6e-68 230.4 0.1 7.8e-68 229.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3140 PF11338.3 CCF50209.1 - 2.8e-31 107.4 4.5 5.9e-31 106.4 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Med22 PF06179.7 CCF50209.1 - 3.8e-11 42.9 0.2 3.8e-11 42.9 0.1 2.6 3 1 0 3 3 3 1 Surfeit locus protein 5 subunit 22 of Mediator complex PLAC9 PF15205.1 CCF50209.1 - 0.054 13.7 0.7 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Placenta-specific protein 9 Ribosomal_S13 PF00416.17 CCF50209.1 - 0.26 11.7 2.5 0.73 10.3 0.8 2.2 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF3237 PF11578.3 CCF50210.1 - 5.8e-30 103.5 0.0 6.6e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Zn_clus PF00172.13 CCF50211.1 - 7.9e-06 25.6 9.3 2e-05 24.3 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.10 CCF50212.1 - 6.5e-50 169.7 0.5 9.1e-24 84.2 0.0 3.5 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCF50212.1 - 0.00042 20.7 0.0 0.0023 18.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF50212.1 - 0.0078 15.9 0.0 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCF50212.1 - 0.02 14.2 0.1 7.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CCF50212.1 - 0.039 14.5 0.3 0.16 12.5 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Fork_head PF00250.13 CCF50214.1 - 6.1e-15 55.0 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCF50214.1 - 0.17 12.0 0.0 1.8 8.7 0.0 2.2 1 1 0 1 1 1 0 FHA domain TRAP_alpha PF03896.11 CCF50214.1 - 0.68 8.8 11.5 1.9 7.4 7.9 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MYCBPAP PF14646.1 CCF50214.1 - 1 7.9 3.2 2 7.0 2.2 1.4 1 0 0 1 1 1 0 MYCBP-associated protein family PI3K_1B_p101 PF10486.4 CCF50214.1 - 2.3 5.7 6.7 3.7 4.9 4.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit eIF-3c_N PF05470.7 CCF50214.1 - 7.2 4.5 8.5 14 3.6 5.9 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus API5 PF05918.6 CCF50215.1 - 0.0039 15.7 0.9 0.0039 15.7 0.6 2.3 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) KIAA1328 PF15369.1 CCF50215.1 - 0.038 13.7 0.2 0.038 13.7 0.1 2.8 3 1 0 3 3 3 0 Uncharacterised protein KIAA1328 DUF3449 PF11931.3 CCF50215.1 - 0.042 13.3 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Ytp1 PF10355.4 CCF50216.1 - 2.7e-98 328.4 2.4 2.7e-98 328.4 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCF50216.1 - 1.6e-22 79.0 1.2 1.6e-22 79.0 0.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Abhydrolase_3 PF07859.8 CCF50217.1 - 4.2e-21 75.5 0.0 9.1e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCF50217.1 - 2.1e-15 56.2 0.0 3.4e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) COesterase PF00135.23 CCF50217.1 - 0.18 10.4 0.1 6.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family SSB PF00436.20 CCF50218.1 - 3.9e-14 52.3 0.0 4.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Aminotran_1_2 PF00155.16 CCF50219.1 - 6.2e-74 249.1 0.0 1.1e-73 248.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCF50219.1 - 6.5e-08 31.7 0.1 1.7e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCF50219.1 - 6.6e-05 21.3 0.0 0.00013 20.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCF50219.1 - 0.00012 21.2 0.2 0.00025 20.2 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CCF50219.1 - 0.0064 15.6 0.2 0.02 14.0 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L12 PF00542.14 CCF50220.1 - 1.6e-17 63.2 11.3 7.5e-17 61.1 4.2 2.5 2 1 1 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CCF50220.1 - 0.0032 17.8 9.8 0.0032 17.8 6.8 2.2 2 1 0 2 2 2 1 60s Acidic ribosomal protein Glyco_tran_WecB PF03808.8 CCF50220.1 - 0.13 11.6 0.2 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DAO PF01266.19 CCF50221.1 - 5.7e-46 157.0 0.0 6.9e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCF50221.1 - 0.0018 18.6 0.0 0.04 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF50221.1 - 0.0059 16.6 0.1 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCF50221.1 - 0.0062 16.6 0.0 0.058 13.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF50221.1 - 0.0085 15.0 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Mqo PF06039.10 CCF50221.1 - 0.029 12.5 0.0 0.056 11.6 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 CCF50221.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 CCF50221.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Snf7 PF03357.16 CCF50222.1 - 1.2e-43 148.4 18.6 1.5e-43 148.1 9.4 2.0 2 0 0 2 2 2 1 Snf7 Atg14 PF10186.4 CCF50222.1 - 0.0021 17.0 6.8 0.0032 16.4 4.7 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 MxiH PF09392.5 CCF50222.1 - 0.045 14.3 1.4 0.23 12.0 1.0 2.3 1 1 0 1 1 1 0 Type III secretion needle MxiH like SBDS_C PF09377.5 CCF50222.1 - 0.1 12.3 1.4 0.19 11.4 0.9 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Birna_RdRp PF04197.7 CCF50222.1 - 0.13 10.3 3.4 0.13 10.2 2.4 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF2450 PF10475.4 CCF50222.1 - 1 8.1 7.0 4.2 6.1 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) THOC7 PF05615.8 CCF50222.1 - 2.2 8.5 12.8 1.3 9.2 6.8 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF724 PF05266.9 CCF50222.1 - 2.3 7.8 10.3 0.54 9.8 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2229 PF09989.4 CCF50222.1 - 3.2 7.1 5.2 3.6 6.9 2.8 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) OmpH PF03938.9 CCF50222.1 - 4.3 7.2 11.7 5.5 6.9 7.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RasGEF PF00617.14 CCF50223.1 - 3e-52 177.0 0.0 4.8e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCF50223.1 - 6e-16 58.4 0.2 1.6e-15 57.0 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif MCM PF00493.18 CCF50224.1 - 1.6e-141 470.9 0.2 2e-141 470.6 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCF50224.1 - 6.8e-19 68.5 0.0 1.9e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCF50224.1 - 2.4e-06 26.8 0.0 0.0011 18.1 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCF50224.1 - 0.00025 20.7 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCF50224.1 - 0.0013 18.3 0.1 0.011 15.3 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 CCF50224.1 - 0.011 16.1 0.2 0.036 14.4 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCF50224.1 - 0.074 12.5 0.0 3.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain FAD-oxidase_C PF02913.14 CCF50225.1 - 1.7e-06 27.5 0.0 2.5e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Methyltransf_27 PF13708.1 CCF50225.1 - 0.038 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TIG PF01833.19 CCF50226.1 - 5.5e-13 48.7 2.4 2.5e-12 46.6 1.7 2.2 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 CCF50226.1 - 8.4e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCF50226.1 - 1.2e-12 46.9 0.4 4.3e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCF50226.1 - 7.2e-09 35.6 1.4 1.4e-08 34.7 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF50226.1 - 8e-09 34.8 0.2 0.00093 19.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCF50226.1 - 9.4e-09 35.5 1.1 6.2e-08 32.9 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Sugar_tr PF00083.19 CCF50227.1 - 1.7e-80 270.8 18.9 2.1e-80 270.5 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF50227.1 - 5.9e-23 81.1 30.8 7.8e-23 80.7 21.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF50228.1 - 2.5e-12 46.1 0.8 2.9e-12 45.9 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter BNR PF02012.15 CCF50229.1 - 2.2e-07 29.6 8.3 0.025 14.3 0.2 4.6 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_2 PF13088.1 CCF50229.1 - 2.8e-07 30.1 0.7 0.00064 19.1 0.2 2.8 1 1 1 2 2 2 2 BNR repeat-like domain Zn_clus PF00172.13 CCF50230.1 - 9.1e-07 28.6 8.3 1.6e-06 27.8 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF50230.1 - 0.0001 21.2 0.2 0.00016 20.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TAT_signal PF10518.4 CCF50231.1 - 0.23 11.5 1.4 0.49 10.5 1.0 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence gag_pre-integrs PF13976.1 CCF50232.1 - 0.0022 17.5 0.0 0.0061 16.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Nop25 PF09805.4 CCF50233.1 - 3.1e-23 82.3 12.3 3.1e-23 82.3 8.5 5.0 5 1 0 5 5 5 1 Nucleolar protein 12 (25kDa) RRM_6 PF14259.1 CCF50233.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50233.1 - 0.085 12.4 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_bind_3 PF03067.10 CCF50234.1 - 1.1e-48 165.9 1.5 1.1e-48 165.9 1.0 1.8 2 0 0 2 2 2 1 Chitin binding domain RseA_C PF03873.8 CCF50234.1 - 0.15 11.9 1.2 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain CAF-1_p150 PF11600.3 CCF50234.1 - 5.3 6.3 5.8 7.9 5.7 4.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_capsid PF06112.6 CCF50234.1 - 8.6 6.3 19.3 22 5.0 13.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_24 PF13578.1 CCF50235.1 - 1.1e-10 42.2 0.0 1.8e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_RNA PF04452.9 CCF50235.1 - 0.0086 15.2 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase Amidase02_C PF12123.3 CCF50235.1 - 0.032 13.8 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase DUF3288 PF11691.3 CCF50235.1 - 0.13 12.0 0.3 0.66 9.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3288) UPF0121 PF03661.8 CCF50237.1 - 2e-22 79.6 6.8 2.9e-22 79.0 4.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ribosomal_60s PF00428.14 CCF50237.1 - 0.2 12.0 4.4 6.9 7.1 2.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_11 PF13414.1 CCF50238.1 - 3.3e-11 42.6 3.1 2.2e-09 36.8 0.0 3.3 3 0 0 3 3 3 2 TPR repeat UBA PF00627.26 CCF50238.1 - 1.8e-07 30.8 0.1 1.2e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain DnaJ PF00226.26 CCF50238.1 - 4.7e-06 26.2 0.3 1.2e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 CCF50238.1 - 0.017 14.7 0.8 1.5 8.5 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50238.1 - 1.5 8.9 11.0 2.5 8.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat JmjC PF02373.17 CCF50239.1 - 1.9e-38 131.1 0.1 1.9e-38 131.1 0.1 3.0 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.12 CCF50239.1 - 2.9e-15 55.4 0.1 1e-14 53.7 0.1 2.0 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.1 CCF50239.1 - 1.2e-10 41.3 0.8 3.4e-10 39.8 0.6 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCF50239.1 - 1.8e-09 37.5 1.7 5e-09 36.1 1.2 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.3 CCF50239.1 - 0.0078 16.1 0.7 0.018 14.9 0.5 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain RVT_2 PF07727.9 CCF50240.1 - 1.3e-33 115.9 0.0 2.1e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.23 CCF50243.1 - 1.1e-65 221.7 0.0 1.4e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BCA_ABC_TP_C PF12399.3 CCF50243.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter ATP-synt_J PF04911.7 CCF50244.1 - 5.2e-25 86.6 0.4 5.7e-25 86.5 0.3 1.0 1 0 0 1 1 1 1 ATP synthase j chain MFS_1 PF07690.11 CCF50245.1 - 7e-32 110.5 38.7 1.5e-31 109.4 26.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF50245.1 - 4.9e-14 51.7 3.1 4.9e-14 51.7 2.2 2.7 3 1 1 4 4 4 1 Sugar (and other) transporter DSPc PF00782.15 CCF50246.1 - 1.6e-20 73.0 0.1 6.2e-18 64.6 0.1 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF50246.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCF50246.1 - 0.068 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF382 PF04037.8 CCF50247.1 - 1.7e-59 199.2 1.4 1.7e-59 199.2 1.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 CCF50247.1 - 4.6e-19 67.5 9.1 1.2e-18 66.2 6.3 1.7 1 0 0 1 1 1 1 PSP DUF3439 PF11921.3 CCF50247.1 - 0.65 9.7 8.8 1.4 8.7 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.17 CCF50247.1 - 0.86 8.5 2.2 0.7 8.8 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter SSP160 PF06933.6 CCF50247.1 - 1.7 6.4 9.3 2.5 5.9 6.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PCI PF01399.22 CCF50248.1 - 9.1e-10 38.7 0.1 4.2e-09 36.6 0.0 2.3 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.8 CCF50248.1 - 0.42 10.0 0.0 0.42 10.0 0.0 3.3 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF882) SNARE_assoc PF09335.6 CCF50249.1 - 1e-14 54.7 1.2 1e-14 54.7 0.8 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein Proteasome PF00227.21 CCF50250.1 - 2.3e-59 199.8 0.4 3e-59 199.5 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF50250.1 - 6.4e-15 54.1 0.1 1.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Linker_histone PF00538.14 CCF50250.1 - 0.036 14.1 0.2 0.098 12.7 0.1 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family DUF2070 PF09843.4 CCF50250.1 - 0.066 12.6 0.1 1.2 8.5 0.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Ion_trans PF00520.26 CCF50251.1 - 1.2e-99 331.5 67.3 1.2e-34 119.3 2.3 5.1 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 CCF50251.1 - 0.00024 19.6 53.5 0.00065 18.2 3.4 6.5 6 2 1 7 7 7 4 Polycystin cation channel gag_pre-integrs PF13976.1 CCF50253.1 - 2.7e-07 30.1 0.5 7e-07 28.7 0.1 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain Herpes_UL46 PF03387.9 CCF50253.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL46 protein HAD_2 PF13419.1 CCF50254.1 - 1.1e-17 64.8 0.0 8.8e-16 58.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF50254.1 - 7.4e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCF50254.1 - 3.3e-05 24.3 0.0 6.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 CCF50254.1 - 0.0082 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase COX4 PF02936.9 CCF50255.1 - 7e-35 119.8 0.1 1.2e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HMG_box_2 PF09011.5 CCF50255.1 - 3.2 8.1 7.2 2.1 8.7 0.1 2.6 2 1 1 3 3 3 0 HMG-box domain SH3BGR PF04908.10 CCF50256.1 - 7.3e-08 32.2 0.9 4.1e-07 29.8 0.0 2.7 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein PUF PF00806.14 CCF50257.1 - 2.9e-14 51.6 0.1 0.00043 19.5 0.0 5.0 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat RNase_PH PF01138.16 CCF50258.1 - 7.7e-24 84.4 1.0 1.5e-23 83.5 0.0 1.9 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCF50258.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 COG7 PF10191.4 CCF50259.1 - 6.3e-39 133.5 24.5 1.3e-33 115.9 14.8 2.1 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Vps53_N PF04100.7 CCF50259.1 - 0.038 12.7 8.0 0.047 12.4 4.5 1.8 1 1 0 1 1 1 0 Vps53-like, N-terminal CDC37_N PF03234.9 CCF50260.1 - 1.7e-52 178.3 7.7 1.7e-52 178.3 5.3 2.3 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CCF50260.1 - 5.7e-25 87.7 6.6 1.3e-23 83.3 0.0 2.7 3 0 0 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CCF50260.1 - 9.4e-18 63.9 2.5 1e-17 63.7 0.0 2.4 2 1 0 2 2 2 1 Cdc37 C terminal domain Fe-S_biosyn PF01521.15 CCF50261.1 - 2.7e-13 49.8 0.0 3.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Imm34 PF15596.1 CCF50261.1 - 0.07 13.3 0.9 0.13 12.4 0.4 1.7 2 0 0 2 2 2 0 Immunity protein 34 NAC PF01849.13 CCF50262.1 - 8.2e-21 73.2 0.0 1.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CCF50262.1 - 0.00048 19.8 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF399 PF04187.8 CCF50262.1 - 0.024 14.1 2.3 0.035 13.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF399 TT_ORF2 PF02957.10 CCF50262.1 - 0.056 14.1 0.5 0.1 13.3 0.3 1.5 1 0 0 1 1 1 0 TT viral ORF2 PMT PF02366.13 CCF50264.1 - 7.3e-70 235.1 19.5 1.7e-69 233.9 13.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCF50264.1 - 1e-26 93.6 1.0 1.8e-26 92.8 0.7 1.4 1 0 0 1 1 1 1 MIR domain GET2 PF08690.5 CCF50265.1 - 2.1e-06 27.2 13.8 0.028 13.6 4.8 3.6 2 2 0 3 3 3 2 GET complex subunit GET2 DUF1180 PF06679.7 CCF50265.1 - 2.2 8.1 4.5 1.1 9.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Hid1 PF12722.2 CCF50266.1 - 3.9e-117 392.1 0.0 2.4e-106 356.4 0.0 2.2 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CCF50266.1 - 3.1e-48 164.4 0.0 9.4e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF3649 PF12365.3 CCF50266.1 - 3.1 7.3 6.0 0.49 9.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) BSD PF03909.12 CCF50267.1 - 7.7e-22 76.7 0.1 5.1e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CCF50267.1 - 1.9e-14 53.0 0.0 4.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DSPc PF00782.15 CCF50268.1 - 1.5e-07 31.0 0.0 5.4e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 CCF50268.1 - 0.00062 19.2 0.1 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 CCF50268.1 - 0.0029 16.9 0.5 0.018 14.3 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCF50268.1 - 0.0085 16.1 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 Inositol hexakisphosphate Chitin_synth_2 PF03142.10 CCF50269.1 - 7.4e-239 793.5 0.1 1e-238 793.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCF50269.1 - 1.1e-14 54.6 5.1 1.1e-14 54.6 3.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF50269.1 - 1.4e-12 47.9 0.1 1.5e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CCF50269.1 - 0.00054 19.2 0.6 0.17 11.1 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CCF50269.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCF50269.1 - 0.23 11.1 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 DASH_Dad1 PF08649.5 CCF50270.1 - 4e-18 64.8 0.0 5.5e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 RVT_1 PF00078.22 CCF50271.1 - 1.1e-05 24.8 1.1 4.1e-05 23.0 0.3 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_3 PF13920.1 CCF50273.1 - 8.2e-07 28.5 6.6 8.2e-07 28.5 4.6 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CCF50274.1 - 1.4e-43 148.3 0.8 2.3e-43 147.6 0.3 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF50274.1 - 1.3e-27 95.4 0.6 1e-26 92.5 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCF50274.1 - 0.00027 20.6 0.2 0.00061 19.4 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CCF50274.1 - 0.00047 20.0 0.0 0.00088 19.1 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CCF50274.1 - 0.015 14.8 0.1 0.042 13.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.1 CCF50274.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CCF50274.1 - 0.056 13.5 0.5 0.17 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 CCF50274.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Zn_clus PF00172.13 CCF50275.1 - 9.3e-10 38.2 8.5 1.7e-09 37.4 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.7 CCF50276.1 - 1.4e-14 54.2 0.0 1.6e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain SNF2_N PF00176.18 CCF50277.1 - 2.7e-69 233.2 0.0 4.9e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF50277.1 - 1.2e-15 57.0 0.0 4.1e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 CCF50277.1 - 3.9e-12 45.7 9.1 3.9e-12 45.7 6.3 2.5 2 0 0 2 2 2 1 HSA HLH PF00010.21 CCF50278.1 - 1.4e-13 50.3 0.0 4.2e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain ATP-synt_Eps PF04627.8 CCF50279.1 - 1.9e-22 78.5 3.6 2.5e-22 78.1 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF423 PF04241.10 CCF50280.1 - 5.5e-25 87.1 2.6 8.3e-25 86.5 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2627 PF11118.3 CCF50280.1 - 0.15 12.1 2.2 0.29 11.2 0.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) rve PF00665.21 CCF50282.1 - 5.1e-17 62.1 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain MFS_1 PF07690.11 CCF50285.1 - 6.9e-08 31.5 13.2 7.2e-05 21.6 0.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TrbC PF04956.8 CCF50285.1 - 8.3 6.4 12.0 2.5 8.1 1.5 3.0 2 1 1 3 3 3 0 TrbC/VIRB2 family Tyrosinase PF00264.15 CCF50287.1 - 3e-18 66.8 4.1 3e-18 66.8 2.8 2.0 1 1 1 2 2 2 1 Common central domain of tyrosinase ASFV_J13L PF05568.6 CCF50287.1 - 2.4 7.6 13.6 0.071 12.6 1.9 2.3 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF866 PF05907.8 CCF50288.1 - 2e-40 137.9 0.0 2.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-CHY PF05495.7 CCF50288.1 - 0.007 16.4 0.7 0.012 15.7 0.5 1.3 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.1 CCF50288.1 - 0.0082 15.7 1.2 0.014 14.9 0.8 1.4 1 0 0 1 1 1 1 Cytochrome c7 Cytochrome_C554 PF13435.1 CCF50288.1 - 0.2 11.6 3.0 0.48 10.4 2.1 1.6 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 CCF50288.1 - 0.68 10.3 4.4 2.8 8.3 3.2 1.7 1 1 0 1 1 1 0 Cytochrome c3 Ribosomal_L44 PF00935.14 CCF50288.1 - 1.4 9.0 4.4 4 7.5 0.3 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Sec15 PF04091.7 CCF50290.1 - 1.2e-70 238.2 0.0 2.2e-70 237.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 CCF50290.1 - 6.4e-05 22.6 1.3 0.00085 18.9 0.3 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 CCF50290.1 - 0.00034 20.5 0.1 0.00034 20.5 0.1 2.4 3 1 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 CCF50290.1 - 0.00076 19.2 0.2 0.0036 17.0 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 CCF50290.1 - 0.0016 18.1 0.3 0.022 14.4 0.2 2.4 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.6 CCF50290.1 - 0.0064 16.3 0.9 0.0064 16.3 0.6 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF762 PF05555.6 CCF50290.1 - 0.034 13.3 0.0 0.098 11.8 0.0 1.8 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) Phage_cap_E PF03864.10 CCF50290.1 - 0.087 11.7 0.0 0.19 10.6 0.0 1.5 1 1 0 1 1 1 0 Phage major capsid protein E DPBB_1 PF03330.13 CCF50291.1 - 3.8e-08 33.2 0.2 3.8e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCF50291.1 - 0.0047 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Barwin family DUF605 PF04652.11 CCF50291.1 - 0.3 10.4 18.7 0.38 10.1 12.9 1.1 1 0 0 1 1 1 0 Vta1 like Cys_Met_Meta_PP PF01053.15 CCF50292.1 - 5.5e-120 400.1 0.0 8.3e-120 399.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 CCF50292.1 - 3.2e-19 68.7 2.2 1.7e-18 66.4 1.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCF50292.1 - 4e-06 26.9 0.6 4.4e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 CCF50292.1 - 0.0065 15.7 0.1 0.023 13.9 0.2 1.9 2 0 0 2 2 2 1 Galactokinase galactose-binding signature NTF2 PF02136.15 CCF50293.1 - 2.7e-09 37.4 0.1 2.6e-07 31.0 0.0 2.6 3 0 0 3 3 3 2 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 CCF50293.1 - 1.9e-08 34.2 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 RNR_inhib PF08591.5 CCF50294.1 - 0.31 11.9 0.0 0.31 11.9 0.0 3.0 3 1 0 3 3 3 0 Ribonucleotide reductase inhibitor Oxysterol_BP PF01237.13 CCF50295.1 - 4e-91 305.1 0.0 5.1e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Phage_stabilise PF11134.3 CCF50295.1 - 0.046 12.3 0.0 0.063 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage stabilisation protein BAF1_ABF1 PF04684.8 CCF50297.1 - 5.8e-05 22.1 35.3 5.8e-05 22.1 24.5 2.8 3 0 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor DUF1676 PF07898.8 CCF50297.1 - 0.022 15.0 2.3 0.059 13.6 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) TPR_1 PF00515.23 CCF50299.1 - 1.1e-55 183.0 26.2 6.5e-08 31.8 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50299.1 - 1.2e-50 165.3 22.2 3.3e-06 26.5 0.1 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CCF50299.1 - 7.6e-48 160.0 22.8 5.8e-11 41.8 0.2 6.4 4 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 CCF50299.1 - 5.1e-36 119.7 17.3 0.0002 20.9 0.0 10.4 7 2 3 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.1 CCF50299.1 - 2.5e-31 105.2 14.7 0.00059 20.2 0.0 10.0 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCF50299.1 - 1.2e-30 105.4 32.8 4.7e-07 30.3 0.3 8.4 4 2 3 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 CCF50299.1 - 7.1e-30 100.4 8.0 0.0041 16.8 0.0 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 CCF50299.1 - 1.9e-28 98.2 20.9 4.3e-06 26.5 0.1 6.8 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 CCF50299.1 - 4e-27 92.1 23.6 8.1e-05 22.5 0.2 10.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCF50299.1 - 1e-22 80.2 15.9 3.2e-06 27.3 0.1 6.7 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_6 PF13174.1 CCF50299.1 - 3.1e-21 74.3 20.7 0.0011 19.3 0.0 10.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCF50299.1 - 3.6e-14 52.3 12.8 0.0077 16.0 0.0 6.1 2 2 3 6 6 6 6 Tetratricopeptide repeat Apc3 PF12895.2 CCF50299.1 - 3.9e-11 42.9 11.9 2.2e-06 27.6 0.8 4.7 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CCF50299.1 - 1.9e-08 33.6 12.8 0.003 16.6 1.7 5.0 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCF50299.1 - 0.003 17.4 16.7 2.3 8.2 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCF50299.1 - 0.017 15.2 0.0 0.017 15.2 0.0 4.6 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF2225 PF09986.4 CCF50299.1 - 0.021 14.3 3.5 1.5 8.1 0.9 2.8 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.5 CCF50299.1 - 0.03 13.1 0.5 2.2 6.9 0.1 2.6 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TOM20_plant PF06552.7 CCF50299.1 - 0.043 13.4 0.6 20 4.6 0.2 3.4 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.4 CCF50299.1 - 0.076 12.8 0.3 36 4.2 0.0 3.6 3 1 1 4 4 4 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 CCF50299.1 - 1.4 8.8 10.4 52 3.8 0.0 5.7 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Actin PF00022.14 CCF50300.1 - 4.8e-50 170.1 0.0 3.6e-26 91.5 0.0 2.4 2 1 0 2 2 2 2 Actin LMBR1 PF04791.11 CCF50300.1 - 3.2 6.2 7.1 4.1 5.8 0.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Nop52 PF05997.7 CCF50301.1 - 3.3e-69 232.6 3.5 1.9e-68 230.1 0.3 2.7 2 1 0 2 2 2 1 Nucleolar protein,Nop52 Spore_coat_CotO PF14153.1 CCF50301.1 - 0.0096 15.3 19.1 0.0096 15.3 13.2 3.6 3 1 1 4 4 4 1 Spore coat protein CotO CobT PF06213.7 CCF50301.1 - 0.14 11.3 68.1 0.062 12.4 13.6 3.2 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT DUF775 PF05603.7 CCF50301.1 - 0.72 9.3 7.0 15 5.0 3.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Anoctamin PF04547.7 CCF50301.1 - 8.5 4.8 11.3 22 3.5 0.1 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel GTP_EFTU PF00009.22 CCF50302.1 - 1.2e-24 86.8 0.0 2.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCF50302.1 - 4.6e-10 39.5 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCF50302.1 - 1.3e-07 31.5 0.8 3.9e-07 30.0 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCF50302.1 - 5.4e-06 25.9 1.9 3.7e-05 23.2 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 CCF50302.1 - 0.02 14.3 0.3 12 5.3 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SOBP PF15279.1 CCF50302.1 - 0.045 14.1 5.9 0.087 13.1 4.1 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein MMR_HSR1 PF01926.18 CCF50302.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF50302.1 - 0.078 12.2 0.1 4.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 CCF50302.1 - 0.078 13.4 2.3 1.9 9.0 0.4 3.3 2 1 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 CCF50302.1 - 0.15 11.6 0.1 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein adh_short_C2 PF13561.1 CCF50303.1 - 1.1e-29 103.9 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCF50303.1 - 9.3e-24 84.2 0.0 1.2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF50303.1 - 8.2e-08 32.1 0.0 1.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 CCF50303.1 - 0.041 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TPT PF03151.11 CCF50304.1 - 4.6e-32 110.7 4.2 4.6e-32 110.7 2.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCF50304.1 - 7.2e-08 32.5 25.3 0.00027 20.9 4.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CCF50304.1 - 0.00029 19.8 15.8 0.0056 15.6 10.9 2.3 1 1 0 1 1 1 1 UAA transporter family Med31 PF05669.7 CCF50305.1 - 2.2e-31 107.6 0.9 2.7e-31 107.3 0.7 1.0 1 0 0 1 1 1 1 SOH1 GSH_synth_ATP PF03917.12 CCF50306.1 - 8.9e-98 327.2 0.0 1.1e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CCF50306.1 - 5.9e-34 116.3 0.0 1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF4610 PF15384.1 CCF50306.1 - 0.14 11.6 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) V-ATPase_H_N PF03224.9 CCF50307.1 - 2.9e-101 338.7 0.0 1.1e-100 336.7 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCF50307.1 - 3.3e-39 133.5 0.0 6.9e-39 132.4 0.0 1.6 1 0 0 1 1 1 1 V-ATPase subunit H Arm PF00514.18 CCF50307.1 - 0.081 12.7 3.0 2.9 7.8 0.1 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CCF50307.1 - 0.11 12.5 0.1 0.9 9.7 0.0 2.5 3 0 0 3 3 3 0 HEAT repeat cwf21 PF08312.7 CCF50307.1 - 0.3 10.9 1.5 0.73 9.7 1.1 1.7 1 0 0 1 1 1 0 cwf21 domain MRP-L46 PF11788.3 CCF50308.1 - 1.9e-23 83.2 0.1 5e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 AAA_32 PF13654.1 CCF50308.1 - 0.021 13.4 0.1 0.033 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Herpes_capsid PF06112.6 CCF50308.1 - 3.8 7.5 19.0 8.4 6.4 0.5 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ATG16 PF08614.6 CCF50309.1 - 1.7e-60 204.2 16.5 2.5e-60 203.6 11.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 CCF50309.1 - 0.0005 19.7 15.6 0.0005 19.7 10.8 2.0 1 1 1 2 2 2 2 IncA protein TMF_TATA_bd PF12325.3 CCF50309.1 - 0.0061 16.2 9.9 0.0061 16.2 6.9 2.8 2 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF2968 PF11180.3 CCF50309.1 - 0.011 15.1 7.3 0.011 15.1 5.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) GAS PF13851.1 CCF50309.1 - 0.092 11.9 21.2 0.016 14.4 10.9 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4457 PF14652.1 CCF50309.1 - 0.14 11.1 2.2 0.15 10.9 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4457) CENP-H PF05837.7 CCF50309.1 - 0.22 11.7 18.5 0.4 10.8 2.0 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF3584 PF12128.3 CCF50309.1 - 0.39 7.9 17.4 0.0063 13.9 7.4 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) USP8_interact PF08941.5 CCF50309.1 - 0.4 9.9 5.1 0.07 12.4 1.0 1.6 2 0 0 2 2 2 0 USP8 interacting Peptidase_S46 PF10459.4 CCF50309.1 - 0.43 8.9 7.7 0.64 8.3 5.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Gon7 PF08738.5 CCF50309.1 - 0.58 10.1 8.9 0.036 14.0 1.4 2.4 1 1 1 2 2 2 0 Gon7 family DUF4061 PF13270.1 CCF50309.1 - 0.69 10.0 10.2 0.18 11.8 3.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) FlaC_arch PF05377.6 CCF50309.1 - 0.73 9.7 8.6 8.8 6.3 0.0 3.6 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 CCF50309.1 - 0.78 9.7 27.9 0.29 11.0 6.3 3.2 3 1 0 3 3 3 0 FlxA-like protein DASH_Dam1 PF08653.5 CCF50309.1 - 4.2 7.2 8.5 5.7 6.7 0.4 3.3 1 1 2 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.1 CCF50309.1 - 6.6 7.1 8.1 5.7 7.4 2.4 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.14 CCF50309.1 - 7.4 4.2 11.1 8.5 4.0 7.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 CCF50309.1 - 9.3 6.3 10.3 11 6.1 5.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prp19_bind PF06991.6 CCF50310.1 - 1e-50 172.5 17.2 1e-50 172.5 11.9 3.3 3 0 0 3 3 3 2 Splicing factor, Prp19-binding domain Zn_clus PF00172.13 CCF50311.1 - 5.2e-05 23.0 8.9 9.5e-05 22.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 CCF50313.1 - 1e-06 27.9 2.5 1.8e-06 27.1 1.7 1.4 1 0 0 1 1 1 1 GATA zinc finger Myc_N PF01056.13 CCF50314.1 - 0.32 10.1 11.0 0.021 13.9 3.5 1.9 2 0 0 2 2 2 0 Myc amino-terminal region PAM2 PF07145.10 CCF50315.1 - 1.9e-06 27.0 6.2 0.21 11.1 0.0 5.7 5 0 0 5 5 5 3 Ataxin-2 C-terminal region Hema_stalk PF08720.5 CCF50315.1 - 0.066 12.7 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk Med7 PF05983.6 CCF50316.1 - 5.3e-48 162.8 1.0 6.9e-48 162.4 0.7 1.2 1 0 0 1 1 1 1 MED7 protein DUF607 PF04678.8 CCF50316.1 - 0.025 14.5 1.9 0.042 13.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 SpoVG PF04026.7 CCF50316.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 SpoVG bZIP_2 PF07716.10 CCF50316.1 - 1.2 9.0 6.6 4 7.3 2.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Aminotran_5 PF00266.14 CCF50317.1 - 5.5e-33 114.2 0.0 6.8e-32 110.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V RF-1 PF00472.15 CCF50318.1 - 2.6e-23 82.0 4.0 6.5e-23 80.7 2.7 1.6 1 0 0 1 1 1 1 RF-1 domain DUF2011 PF09428.5 CCF50318.1 - 2.2 8.1 14.4 4.4 7.1 10.0 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) Chromo PF00385.19 CCF50319.1 - 2.2e-06 27.2 0.2 4.2e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Y_phosphatase2 PF03162.8 CCF50320.1 - 1.3e-39 135.2 0.0 4e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Lin-8 PF03353.10 CCF50320.1 - 0.097 11.9 0.5 0.15 11.3 0.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CCF50320.1 - 1.6 6.9 4.3 1.4 7.1 3.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Slx4 PF09494.5 CCF50321.1 - 3.9e-17 61.7 0.0 7.2e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Glyco_hydro_cc PF11790.3 CCF50322.1 - 1.1e-60 205.0 4.2 1.4e-60 204.7 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Antimicrobial11 PF08106.6 CCF50322.1 - 0.29 11.0 2.5 0.52 10.2 1.8 1.4 1 0 0 1 1 1 0 Formaecin family EamA PF00892.15 CCF50323.1 - 1.7e-10 40.9 33.9 4.5e-08 33.1 4.7 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCF50323.1 - 7.9e-08 32.4 4.9 7.9e-08 32.4 3.4 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Sec20 PF03908.8 CCF50324.1 - 1.5e-17 63.0 1.6 1.5e-17 63.0 1.1 2.2 2 0 0 2 2 2 1 Sec20 Glypican PF01153.14 CCF50324.1 - 0.0029 16.2 0.4 0.0044 15.7 0.3 1.2 1 0 0 1 1 1 1 Glypican Syntaxin-6_N PF09177.6 CCF50324.1 - 0.025 14.9 10.6 0.39 11.1 1.4 4.1 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 CCF50324.1 - 1.2 8.9 9.8 0.3 10.9 0.5 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.8 CCF50324.1 - 3.2 8.1 14.8 0.16 12.3 2.8 3.7 3 1 1 4 4 4 0 Histidine kinase Syntaxin PF00804.20 CCF50324.1 - 4.1 7.6 9.9 0.35 11.0 2.0 2.5 2 1 1 3 3 3 0 Syntaxin Fib_alpha PF08702.5 CCF50324.1 - 5.1 7.2 6.0 2.4 8.2 0.3 2.6 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_L16 PF00252.13 CCF50325.1 - 1.8e-40 137.7 0.2 2.3e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e HSCB_C PF07743.8 CCF50326.1 - 6e-15 55.4 10.3 9.8e-15 54.7 7.1 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCF50326.1 - 4.7e-08 32.6 0.0 1.1e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.2 CCF50326.1 - 0.017 14.9 0.9 0.034 13.9 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon CRF PF00473.12 CCF50326.1 - 0.02 14.9 2.6 0.051 13.6 1.8 1.7 1 0 0 1 1 1 0 Corticotropin-releasing factor family zf-ribbon_3 PF13248.1 CCF50326.1 - 0.034 13.3 1.0 0.068 12.3 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain cwf21 PF08312.7 CCF50326.1 - 0.1 12.4 4.2 0.22 11.3 2.9 1.5 1 0 0 1 1 1 0 cwf21 domain DUF607 PF04678.8 CCF50326.1 - 0.13 12.1 1.6 0.2 11.5 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 GST_C PF00043.20 CCF50326.1 - 0.16 11.9 1.5 3.3 7.7 1.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF972 PF06156.8 CCF50326.1 - 0.29 11.4 2.5 0.63 10.4 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) UPF0547 PF10571.4 CCF50326.1 - 1.1 8.9 3.9 2.2 8.0 2.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 VP_N-CPKC PF11475.3 CCF50326.1 - 7.6 6.1 7.8 4.2 6.9 0.7 2.5 1 1 1 2 2 2 0 Virion protein N terminal domain PSP1 PF04468.7 CCF50327.1 - 2.8e-31 107.3 0.4 4.1e-31 106.7 0.3 1.2 1 0 0 1 1 1 1 PSP1 C-terminal conserved region EF-hand_4 PF12763.2 CCF50328.1 - 1.4e-38 130.7 0.0 6e-15 54.8 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 CCF50328.1 - 6.6e-07 28.9 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ERM PF00769.14 CCF50328.1 - 3.1e-06 26.9 14.6 8.2e-06 25.5 10.1 1.8 1 0 0 1 1 1 1 Ezrin/radixin/moesin family EF-hand_7 PF13499.1 CCF50328.1 - 4.5e-06 26.7 0.0 0.22 11.6 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair UBA_3 PF09288.5 CCF50328.1 - 0.00011 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain TMCO5 PF14992.1 CCF50328.1 - 0.061 12.4 22.0 0.095 11.8 15.3 1.2 1 0 0 1 1 1 0 TMCO5 family CENP-Q PF13094.1 CCF50328.1 - 0.16 11.9 33.6 0.019 14.9 8.6 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.6 CCF50328.1 - 3.5 7.3 30.2 7.5 6.3 8.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PAC2 PF09754.4 CCF50329.1 - 1.7e-23 83.6 0.0 5.3e-23 82.0 0.0 1.7 1 1 0 1 1 1 1 PAC2 family Proteasome PF00227.21 CCF50330.1 - 2.3e-49 167.2 0.1 3e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCF50330.1 - 1.7e-08 33.6 0.2 3.5e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF4520 PF15016.1 CCF50330.1 - 0.027 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) DUF4116 PF13475.1 CCF50330.1 - 0.049 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Gp-FAR-1 PF05823.7 CCF50330.1 - 0.078 12.9 0.1 0.88 9.5 0.0 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Aminotran_4 PF01063.14 CCF50331.1 - 3.6e-22 78.9 0.0 9.3e-22 77.6 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class IV RNA_POL_M_15KD PF02150.11 CCF50332.1 - 8.8e-13 47.7 2.6 8.8e-13 47.7 1.8 3.2 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CCF50332.1 - 8.6e-12 44.4 8.8 2.9e-11 42.7 0.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Elf1 PF05129.8 CCF50332.1 - 0.017 14.8 2.7 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.1 CCF50332.1 - 0.1 12.8 3.9 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2197 PF09963.4 CCF50332.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2197) CpXC PF14353.1 CCF50332.1 - 0.27 11.1 9.6 9.1 6.2 0.0 3.2 1 1 2 3 3 3 0 CpXC protein Zn-ribbon_8 PF09723.5 CCF50332.1 - 0.33 10.9 10.9 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Crust_neurohorm PF01147.12 CCF50332.1 - 0.85 8.9 5.6 1.4 8.2 0.4 2.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Lar_restr_allev PF14354.1 CCF50332.1 - 1.3 9.3 9.2 0.39 11.0 1.6 2.6 2 2 0 2 2 2 0 Restriction alleviation protein Lar DUF3133 PF11331.3 CCF50332.1 - 2.3 7.8 9.3 1.2 8.7 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3133) zf-ribbon_3 PF13248.1 CCF50332.1 - 2.5 7.4 10.0 42 3.5 4.0 3.2 2 1 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 CCF50332.1 - 5.9 6.9 13.2 0.88 9.6 0.8 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain Rubredoxin PF00301.15 CCF50332.1 - 6.6 6.6 10.4 26 4.7 0.1 3.6 4 0 0 4 4 4 0 Rubredoxin zf-C2H2_4 PF13894.1 CCF50332.1 - 6.9 7.2 8.9 7.9 7.0 1.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.2 CCF50332.1 - 7.9 6.3 12.9 5.8 6.8 0.5 3.0 2 1 0 2 2 2 0 Transposase zinc-ribbon domain HypA PF01155.14 CCF50332.1 - 8 6.1 7.5 0.7 9.6 1.6 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sel1 PF08238.7 CCF50333.1 - 5.5e-12 45.9 22.4 6.8e-05 23.3 0.4 4.4 4 0 0 4 4 4 3 Sel1 repeat Vma12 PF11712.3 CCF50334.1 - 3.4e-30 104.5 0.1 7.1e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF89 PF01937.14 CCF50335.1 - 3.6e-109 364.8 0.0 1.6e-78 264.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 DUF399 PF04187.8 CCF50336.1 - 2.5e-22 79.4 1.3 4.3e-13 49.2 0.0 4.1 3 1 0 3 3 3 3 Protein of unknown function, DUF399 DPBB_1 PF03330.13 CCF50337.1 - 0.0021 18.0 0.0 0.0054 16.7 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel EBV-NA3 PF05009.7 CCF50338.1 - 0.13 11.5 0.6 0.18 11.0 0.4 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Not1 PF04054.10 CCF50339.1 - 8.4e-107 357.3 0.0 2.4e-106 355.7 0.0 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCF50339.1 - 8.9e-55 184.4 3.9 2.9e-54 182.7 2.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF4159 PF13709.1 CCF50339.1 - 0.074 12.1 0.0 0.23 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) DUF572 PF04502.8 CCF50339.1 - 0.47 9.6 1.9 0.92 8.6 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) WW PF00397.21 CCF50340.1 - 5.7e-06 26.0 10.3 0.034 14.0 5.9 2.7 2 0 0 2 2 2 2 WW domain Pkinase PF00069.20 CCF50342.1 - 1.1e-70 237.8 0.0 1.4e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50342.1 - 9.4e-50 169.0 0.0 1.3e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50342.1 - 2e-06 26.9 0.0 4.8e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.11 CCF50342.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.20 CCF50343.1 - 5.8e-70 235.4 0.0 7.5e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50343.1 - 1e-30 106.6 0.0 1.3e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50343.1 - 3.2e-08 32.8 0.0 1.2e-07 31.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CCF50343.1 - 0.001 18.2 0.0 0.0021 17.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCF50343.1 - 0.0018 17.6 0.1 0.0041 16.4 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CCF50343.1 - 0.0021 17.8 0.0 0.0047 16.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family 5_nucleotid PF05761.9 CCF50343.1 - 0.058 11.9 0.1 0.058 11.9 0.1 1.6 2 0 0 2 2 2 0 5' nucleotidase family DOT1 PF08123.8 CCF50344.1 - 2.4e-55 187.0 0.0 3.3e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CCF50344.1 - 0.0068 16.4 0.0 0.026 14.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF50344.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Mito_carr PF00153.22 CCF50345.1 - 1e-49 166.1 2.4 1.1e-17 63.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DIE2_ALG10 PF04922.7 CCF50346.1 - 1.4e-68 231.6 4.3 1.5e-53 182.2 1.6 3.1 2 2 0 2 2 2 2 DIE2/ALG10 family zf-DHHC PF01529.15 CCF50346.1 - 6.6 6.0 5.2 1.6 8.1 0.5 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cu-oxidase_3 PF07732.10 CCF50347.1 - 2.5e-29 101.4 0.2 2.4e-28 98.2 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 CCF50347.1 - 9.5e-21 74.3 0.0 5.6e-18 65.3 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCF50347.1 - 1.4e-16 60.2 4.7 4.4e-14 52.1 1.1 4.1 4 1 0 4 4 4 1 Multicopper oxidase NAD_binding_5 PF07994.7 CCF50348.1 - 1.4e-109 366.1 0.0 1.8e-109 365.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCF50348.1 - 5.2e-44 148.6 0.1 9e-44 147.8 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase HOOK PF05622.7 CCF50349.1 - 3.8e-47 160.5 43.4 3.8e-47 160.5 30.1 3.8 1 1 1 3 3 3 2 HOOK protein CH PF00307.26 CCF50349.1 - 8.9e-05 22.4 1.3 0.0021 18.0 0.0 3.6 4 0 0 4 4 4 1 Calponin homology (CH) domain DUF3584 PF12128.3 CCF50349.1 - 0.00041 17.8 46.7 0.00041 17.8 32.4 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF3584) Sec20 PF03908.8 CCF50349.1 - 0.034 13.8 14.4 0.26 11.0 2.5 4.2 3 2 0 3 3 3 0 Sec20 DUF4108 PF13390.1 CCF50349.1 - 0.13 12.0 7.0 0.82 9.3 4.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) DUF812 PF05667.6 CCF50349.1 - 0.41 9.1 59.9 0.084 11.3 24.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) NYD-SP28_assoc PF14775.1 CCF50349.1 - 0.75 9.5 13.6 0.033 13.8 1.2 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain Reo_sigmaC PF04582.7 CCF50349.1 - 1.1 8.3 30.7 0.16 11.0 0.7 4.9 2 2 4 6 6 6 0 Reovirus sigma C capsid protein DUF837 PF05769.6 CCF50350.1 - 0.0014 18.1 3.4 0.0014 18.1 2.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF837) TRAPP PF04051.11 CCF50351.1 - 1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Methyltransf_23 PF13489.1 CCF50352.1 - 4.9e-14 52.3 0.1 1.1e-13 51.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF50352.1 - 8e-12 45.5 0.0 1.8e-11 44.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CCF50352.1 - 5.1e-06 25.9 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CCF50352.1 - 2.1e-05 24.8 0.0 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF50352.1 - 4.7e-05 23.0 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF50352.1 - 8.7e-05 23.0 0.0 0.00023 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF50352.1 - 0.00013 22.0 0.0 0.00039 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF50352.1 - 0.0015 18.9 0.0 0.0059 17.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CCF50352.1 - 0.012 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Med8 PF10232.4 CCF50352.1 - 0.037 13.5 0.2 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Methyltransf_4 PF02390.12 CCF50352.1 - 0.055 12.5 0.0 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase TPMT PF05724.6 CCF50352.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SR-25 PF10500.4 CCF50352.1 - 2.7 7.4 10.8 4.1 6.8 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Arf PF00025.16 CCF50353.1 - 5.6e-64 214.5 0.0 6.4e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCF50353.1 - 4.1e-14 52.2 0.0 5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CCF50353.1 - 6e-13 49.3 0.0 7.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCF50353.1 - 1.4e-12 47.2 0.0 1.7e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCF50353.1 - 1.7e-11 43.4 0.8 3.3e-09 35.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CCF50353.1 - 1.4e-09 37.8 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF50353.1 - 5.2e-08 32.5 0.0 1.4e-05 24.5 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF50353.1 - 6.3e-08 32.0 0.0 7.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CCF50353.1 - 0.0012 18.1 0.4 0.0057 15.9 0.1 2.0 1 1 1 2 2 2 1 Ferrous iron transport protein B Mannosyl_trans2 PF04188.8 CCF50354.1 - 1.3e-62 212.1 12.3 1.6e-62 211.9 8.6 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF1757 PF08560.5 CCF50355.1 - 0.0015 18.2 0.1 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) LSM14 PF12701.2 CCF50356.1 - 3.3e-32 110.1 0.0 7.1e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CCF50356.1 - 9.7e-11 42.1 1.9 0.0005 20.5 0.3 2.6 2 0 0 2 2 2 2 FDF domain SM-ATX PF14438.1 CCF50356.1 - 0.0002 21.2 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Bromodomain PF00439.20 CCF50357.1 - 2.4e-19 69.0 0.0 6.2e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 Bromodomain BAH PF01426.13 CCF50357.1 - 8e-11 41.7 0.2 1.4e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 BAH domain Lon_C PF05362.8 CCF50358.1 - 1e-68 230.7 0.0 1.6e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CCF50358.1 - 4.4e-23 81.9 0.0 9.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CCF50358.1 - 1.3e-12 47.8 0.0 2.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CCF50358.1 - 2.5e-10 40.2 0.0 8e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CCF50358.1 - 8.8e-09 34.9 0.0 1.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 CCF50358.1 - 6.4e-05 23.0 0.6 0.00025 21.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CCF50358.1 - 7.5e-05 22.7 0.0 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCF50358.1 - 8.4e-05 22.7 0.2 0.0061 16.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCF50358.1 - 0.00033 20.3 0.1 0.00098 18.8 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCF50358.1 - 0.00036 21.3 1.7 0.00092 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCF50358.1 - 0.0014 18.4 0.0 0.0057 16.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCF50358.1 - 0.0015 18.8 2.8 0.012 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCF50358.1 - 0.004 16.7 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCF50358.1 - 0.0049 15.9 0.0 0.057 12.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CCF50358.1 - 0.0049 16.2 0.0 0.018 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCF50358.1 - 0.0071 15.5 0.1 0.019 14.1 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCF50358.1 - 0.0096 14.6 0.0 0.1 11.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 CCF50358.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CCF50358.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCF50358.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CCF50358.1 - 0.025 14.1 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCF50358.1 - 0.029 13.4 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 CCF50358.1 - 0.029 13.5 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_PrkA PF08298.6 CCF50358.1 - 0.042 12.5 0.0 0.37 9.4 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain KaiC PF06745.8 CCF50358.1 - 0.072 12.1 0.0 21 4.1 0.0 3.1 3 0 0 3 3 3 0 KaiC NACHT PF05729.7 CCF50358.1 - 0.085 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SinI PF08671.5 CCF50358.1 - 0.11 11.8 0.2 0.43 10.0 0.1 2.0 2 0 0 2 2 2 0 Anti-repressor SinI UPF0079 PF02367.12 CCF50358.1 - 0.12 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CCF50358.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.2 1 1 1 2 2 1 0 AAA domain eIF-5_eIF-2B PF01873.12 CCF50359.1 - 7.9e-41 138.6 0.0 1.2e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCF50359.1 - 3.9e-24 84.4 0.0 3.9e-24 84.4 0.0 2.8 4 0 0 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Nucleoplasmin PF03066.10 CCF50359.1 - 0.0018 17.7 0.8 0.0018 17.7 0.6 2.7 3 0 0 3 3 3 1 Nucleoplasmin Cwf_Cwc_15 PF04889.7 CCF50359.1 - 0.2 11.3 8.9 0.16 11.6 1.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Myb_DNA-bind_5 PF13873.1 CCF50361.1 - 0.00016 21.4 1.5 0.0015 18.4 0.5 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 CCF50362.1 - 5.7e-14 52.0 0.0 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease MAPEG PF01124.13 CCF50363.1 - 2.1e-20 72.6 3.5 3.1e-20 72.1 2.4 1.2 1 0 0 1 1 1 1 MAPEG family Ferritin_2 PF13668.1 CCF50364.1 - 1.6e-41 141.4 0.1 2.8e-41 140.6 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Cullin PF00888.17 CCF50365.1 - 4.2e-126 421.8 1.3 6.6e-126 421.2 0.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCF50365.1 - 1.3e-23 82.6 1.9 3e-23 81.3 1.4 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF913 PF06025.7 CCF50366.1 - 6.3e-113 377.3 0.0 6.3e-113 377.3 0.0 5.1 7 0 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 CCF50366.1 - 1.9e-90 303.5 3.4 2.4e-90 303.1 0.6 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 CCF50366.1 - 5e-20 71.4 1.9 5e-20 71.4 1.3 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 CCF50366.1 - 4.2e-10 39.1 0.0 1.6e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain APG6 PF04111.7 CCF50366.1 - 1.8 7.5 7.2 3.7 6.4 5.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Prominin PF05478.6 CCF50366.1 - 9.2 3.6 4.6 4.7 4.6 0.8 2.0 2 0 0 2 2 2 0 Prominin PDEase_II PF02112.10 CCF50368.1 - 1.4e-40 139.2 3.4 5.1e-24 84.8 0.0 3.7 5 0 0 5 5 5 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CCF50368.1 - 6.6e-05 22.5 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain OPT PF03169.10 CCF50369.1 - 2.5e-182 607.6 51.7 2.9e-182 607.4 35.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HEAT PF02985.17 CCF50370.1 - 5.2e-13 47.8 17.7 0.0015 18.4 0.0 9.9 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 CCF50370.1 - 2.2e-11 43.8 11.9 0.00013 22.1 0.1 5.5 4 1 1 5 5 5 4 HEAT repeats Adaptin_N PF01602.15 CCF50370.1 - 0.00057 18.3 0.2 0.015 13.6 0.0 2.4 3 0 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 CCF50370.1 - 0.25 11.1 0.1 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Atg8 PF02991.11 CCF50371.1 - 3.8e-52 174.6 0.1 4.3e-52 174.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCF50371.1 - 6.8e-07 29.3 0.0 8.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SPT16 PF08644.6 CCF50372.1 - 7.9e-56 188.1 0.0 2.7e-55 186.3 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CCF50372.1 - 1.1e-49 168.0 1.0 3.5e-49 166.4 0.7 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CCF50372.1 - 1.4e-25 90.0 0.1 3.4e-25 88.8 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Rtt106 PF08512.7 CCF50372.1 - 1.1e-22 79.8 0.2 5.1e-21 74.4 0.0 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF1378 PF07125.6 CCF50372.1 - 0.0015 18.4 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1378) Peptidase_C39_2 PF13529.1 CCF50372.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 Peptidase_C39 like family DNA_binding_1 PF01035.15 CCF50373.1 - 2.2e-23 81.7 0.1 3.8e-23 81.0 0.0 1.4 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Prion PF00377.13 CCF50373.1 - 0.018 14.7 0.1 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain UPF0126 PF03458.8 CCF50374.1 - 3.4 7.3 8.3 1.8 8.2 0.3 2.9 3 0 0 3 3 3 0 UPF0126 domain Abhydrolase_6 PF12697.2 CCF50375.1 - 3.7e-27 95.6 0.0 4.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF50375.1 - 1.3e-12 47.6 0.0 2.6e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF50375.1 - 1.3e-12 47.7 0.0 1.2e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CCF50375.1 - 0.0025 18.0 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.16 CCF50375.1 - 0.008 15.4 0.1 0.17 11.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 CCF50375.1 - 0.0095 15.2 0.0 0.81 8.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.15 CCF50375.1 - 0.026 13.9 0.1 0.056 12.8 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 CCF50375.1 - 0.064 12.6 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 CCF50375.1 - 0.072 12.3 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase AAA PF00004.24 CCF50376.1 - 1.8e-33 115.5 0.1 3e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF50376.1 - 4.2e-08 33.3 0.0 9.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCF50376.1 - 9.3e-08 32.2 0.1 2.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF50376.1 - 1.1e-06 29.4 0.0 2.4e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF50376.1 - 5.8e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCF50376.1 - 1.3e-05 24.6 0.7 0.01 15.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCF50376.1 - 1.5e-05 24.6 0.1 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CCF50376.1 - 1.6e-05 25.2 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCF50376.1 - 2.1e-05 24.5 0.0 4.9e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 CCF50376.1 - 5.3e-05 22.9 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCF50376.1 - 0.00014 21.6 0.5 0.013 15.2 0.4 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CCF50376.1 - 0.00016 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF50376.1 - 0.0003 19.9 0.0 0.00055 19.0 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CCF50376.1 - 0.00038 20.1 0.3 0.0024 17.5 0.2 2.1 1 1 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 CCF50376.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 CCF50376.1 - 0.001 18.8 0.4 0.0038 16.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCF50376.1 - 0.0012 19.0 0.0 0.0032 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.8 CCF50376.1 - 0.0014 17.5 0.2 0.012 14.5 0.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 CCF50376.1 - 0.0018 17.3 0.0 0.0025 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 CCF50376.1 - 0.0021 17.0 0.1 1.3 7.9 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain IstB_IS21 PF01695.12 CCF50376.1 - 0.0023 17.3 0.0 0.0059 16.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 CCF50376.1 - 0.0024 16.9 0.0 0.0053 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CCF50376.1 - 0.0028 17.2 0.1 0.0072 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CCF50376.1 - 0.004 16.6 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 CCF50376.1 - 0.0042 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCF50376.1 - 0.0062 15.3 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus ABC_tran PF00005.22 CCF50376.1 - 0.007 16.6 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_30 PF13604.1 CCF50376.1 - 0.008 15.7 1.4 0.027 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain Rad51 PF08423.6 CCF50376.1 - 0.012 14.5 0.2 0.4 9.5 0.1 2.1 1 1 0 2 2 2 0 Rad51 AAA_23 PF13476.1 CCF50376.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCF50376.1 - 0.023 13.9 0.1 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CCF50376.1 - 0.034 13.3 0.0 0.085 12.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCF50376.1 - 0.053 12.6 0.3 0.94 8.5 0.0 2.2 1 1 1 2 2 2 0 KaiC PduV-EutP PF10662.4 CCF50376.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCF50376.1 - 0.075 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 CCF50376.1 - 0.077 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCF50376.1 - 0.082 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 CCF50376.1 - 0.11 10.9 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CCF50376.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 CCF50376.1 - 0.13 11.9 0.2 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 NTPase DUF258 PF03193.11 CCF50376.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cyclin PF08613.6 CCF50377.1 - 1.4e-16 61.2 0.0 3.7e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCF50377.1 - 2.6e-07 30.2 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cas_TM1802 PF09484.5 CCF50377.1 - 0.29 9.5 0.1 0.41 9.0 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) WD40 PF00400.27 CCF50378.1 - 1e-06 28.3 9.4 2.4e-05 24.0 1.0 5.6 5 1 0 5 5 5 1 WD domain, G-beta repeat DUF2415 PF10313.4 CCF50378.1 - 8e-05 22.2 0.1 0.00022 20.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.7 CCF50378.1 - 0.24 11.1 4.3 0.93 9.2 0.2 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-HC5HC2H_2 PF13832.1 CCF50379.1 - 5.1e-21 74.7 26.0 2.2e-20 72.6 3.4 4.1 4 0 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.24 CCF50379.1 - 1.6e-15 56.5 23.8 2.5e-10 39.8 4.3 5.8 6 1 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.1 CCF50379.1 - 2.6e-15 56.3 7.2 2.6e-15 56.3 5.0 4.7 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD_2 PF13831.1 CCF50379.1 - 8.1e-09 34.6 4.4 8.1e-09 34.6 3.1 5.2 7 0 0 7 7 7 2 PHD-finger BAH PF01426.13 CCF50379.1 - 1.6e-08 34.2 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 CCF50379.1 - 1.2e-06 27.7 2.4 1.2e-06 27.7 1.6 3.6 3 0 0 3 3 3 1 GATA zinc finger ELM2 PF01448.19 CCF50379.1 - 0.12 12.9 0.0 0.42 11.3 0.0 1.9 1 0 0 1 1 1 0 ELM2 domain bZIP_1 PF00170.16 CCF50380.1 - 8.5e-05 22.4 8.2 8.5e-05 22.4 5.7 2.7 2 1 1 3 3 3 1 bZIP transcription factor EndoU_bacteria PF14436.1 CCF50380.1 - 0.02 14.6 1.0 0.038 13.8 0.1 1.9 2 0 0 2 2 2 0 Bacterial EndoU nuclease NP1-WLL PF11733.3 CCF50380.1 - 0.036 14.3 1.0 0.036 14.3 0.7 3.5 3 1 1 4 4 4 0 Non-capsid protein NP1 bZIP_2 PF07716.10 CCF50380.1 - 0.34 10.7 9.3 2.5 7.9 5.8 2.6 1 1 1 2 2 2 0 Basic region leucine zipper DUF488 PF04343.8 CCF50380.1 - 0.51 10.7 4.2 3.8 7.8 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF488 Utp14 PF04615.8 CCF50380.1 - 3.5 5.6 26.7 4.5 5.3 18.5 1.1 1 0 0 1 1 1 0 Utp14 protein SPRY PF00622.23 CCF50381.1 - 4.4e-21 75.2 0.2 8e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 SPRY domain TMEM154 PF15102.1 CCF50381.1 - 0.12 12.0 0.2 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Arf PF00025.16 CCF50382.1 - 2e-77 258.3 0.0 2.4e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCF50382.1 - 9.9e-13 47.7 0.0 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCF50382.1 - 9.5e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCF50382.1 - 1.1e-10 40.8 1.2 6.8e-07 28.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCF50382.1 - 1e-09 37.8 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF50382.1 - 2.4e-07 31.2 0.0 3.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCF50382.1 - 0.00016 21.6 0.0 0.00035 20.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCF50382.1 - 0.0013 17.8 0.1 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CCF50382.1 - 0.045 13.1 0.0 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Cys_Met_Meta_PP PF01053.15 CCF50383.1 - 4.9e-148 492.5 0.0 5.6e-148 492.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCF50383.1 - 7.3e-11 41.7 0.1 1.2e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCF50383.1 - 8.6e-10 37.8 0.1 1.4e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCF50383.1 - 2.1e-07 30.2 0.1 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF50383.1 - 2.9e-05 23.3 0.0 3.9e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CCF50383.1 - 0.00095 17.5 0.0 0.0012 17.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CCF50383.1 - 0.021 13.5 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Topo_Zn_Ribbon PF08272.6 CCF50384.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like UDPGP PF01704.13 CCF50385.1 - 1.5e-182 606.8 0.5 1.7e-182 606.6 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RRM_5 PF13893.1 CCF50386.1 - 9.7e-15 54.1 0.0 3.7e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50386.1 - 2.3e-10 39.9 0.0 2.3e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50386.1 - 0.00011 22.0 0.0 0.15 12.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF50386.1 - 0.0088 15.8 1.8 1.9 8.3 0.0 2.9 1 1 2 3 3 3 2 RNA binding motif NARP1 PF12569.3 CCF50386.1 - 0.19 10.4 2.2 0.27 9.9 1.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dioxygenase_C PF00775.16 CCF50387.1 - 5.1e-47 159.4 0.0 7.3e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 CCF50387.1 - 2.7e-14 52.8 0.0 4.5e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 CCF50387.1 - 3.8e-06 26.8 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 CCF50387.1 - 0.034 14.1 0.0 0.09 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) MG1 PF11974.3 CCF50387.1 - 0.093 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain Mito_carr PF00153.22 CCF50389.1 - 5.2e-65 215.2 0.2 1.4e-21 75.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein YibE_F PF07907.6 CCF50389.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 YibE/F-like protein MOR2-PAG1_mid PF14228.1 CCF50389.1 - 0.11 10.0 0.0 0.15 9.5 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region adh_short PF00106.20 CCF50391.1 - 1.9e-18 66.9 2.5 4.2e-10 39.7 0.3 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCF50391.1 - 6.3e-15 55.5 0.0 2e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF50391.1 - 0.00018 21.1 2.2 0.00085 19.0 0.2 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_7 PF13241.1 CCF50391.1 - 0.02 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1776 PF08643.5 CCF50391.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.22 CCF50391.1 - 0.05 14.0 0.8 0.13 12.6 0.6 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCF50391.1 - 0.09 12.8 0.2 0.26 11.3 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_5 PF07728.9 CCF50393.1 - 8.9e-62 206.9 0.0 4.9e-26 91.1 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) Response_reg PF00072.19 CCF50395.1 - 1.1e-22 80.1 0.2 8.9e-16 57.9 0.1 2.3 1 1 1 2 2 2 2 Response regulator receiver domain DUF202 PF02656.10 CCF50396.1 - 9.8e-12 44.9 5.2 9.8e-12 44.9 3.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CCF50396.1 - 0.31 10.9 0.3 0.31 10.9 0.2 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2615 PF11027.3 CCF50396.1 - 0.65 9.9 3.5 0.5 10.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF3429 PF11911.3 CCF50397.1 - 2e-38 131.5 13.0 2e-38 131.5 9.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3429) DDHD PF02862.12 CCF50397.1 - 4.4 7.0 10.3 5 6.8 3.4 2.1 2 0 0 2 2 2 0 DDHD domain COX14 PF14880.1 CCF50398.1 - 0.003 17.1 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase c assembly PPR_2 PF13041.1 CCF50399.1 - 5.3e-13 48.7 0.1 3.7e-12 46.0 0.0 2.5 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 CCF50399.1 - 4.3e-07 29.4 0.2 0.0081 16.0 0.0 3.7 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CCF50399.1 - 6.8e-07 29.0 0.1 0.0018 18.4 0.0 4.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCF50399.1 - 0.00014 21.2 0.2 0.22 11.0 0.0 2.9 3 0 0 3 3 3 2 PPR repeat DUF1018 PF06252.7 CCF50399.1 - 0.0082 16.6 0.8 0.26 11.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1018) CHCH PF06747.8 CCF50400.1 - 2.8e-06 27.1 6.5 2.8e-06 27.1 4.5 2.3 2 0 0 2 2 2 1 CHCH domain Pet191_N PF10203.4 CCF50400.1 - 0.19 11.7 10.8 1.3 9.0 5.6 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CCF50400.1 - 4.3 7.1 13.5 3.5 7.4 3.2 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 CCF50400.1 - 6.3 6.8 12.1 4.3 7.4 4.9 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Iso_dh PF00180.15 CCF50401.1 - 6.1e-99 331.2 0.0 7.4e-99 330.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aldedh PF00171.17 CCF50402.1 - 1.1e-142 475.6 0.0 1.3e-142 475.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCF50402.1 - 5.6e-05 22.4 0.0 0.00014 21.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Zn_clus PF00172.13 CCF50403.1 - 0.00029 20.6 10.1 0.00057 19.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CCF50403.1 - 0.15 12.2 8.3 0.42 10.8 5.7 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Sugar_tr PF00083.19 CCF50405.1 - 2.3e-101 339.6 21.8 2.8e-101 339.3 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF50405.1 - 1.8e-22 79.5 24.2 1.8e-22 79.5 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCF50405.1 - 0.064 13.0 1.7 0.48 10.2 0.0 3.0 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 CCF50405.1 - 1.1 7.3 13.1 0.071 11.2 1.6 2.9 3 0 0 3 3 3 0 Transmembrane secretion effector DUF2614 PF11023.3 CCF50405.1 - 1.5 8.6 6.2 9.1 6.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) SGL PF08450.7 CCF50407.1 - 3.2e-13 49.6 0.3 4.2e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region DUF772 PF05598.6 CCF50408.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Transposase domain (DUF772) 3-HAO PF06052.7 CCF50411.1 - 3.5e-57 192.0 0.0 4.4e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 CCF50411.1 - 1.4e-06 27.6 0.0 2.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 CCF50411.1 - 0.00077 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 CCF50411.1 - 0.0064 16.4 0.0 0.0094 15.9 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.14 CCF50411.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Snf7 PF03357.16 CCF50412.1 - 3.9e-22 78.4 8.4 4.6e-22 78.1 5.8 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 CCF50412.1 - 0.00054 19.3 1.9 0.00082 18.8 1.3 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway IMP_cyclohyd PF07826.6 CCF50412.1 - 0.052 12.8 0.1 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein SYCE1 PF15233.1 CCF50412.1 - 0.42 10.5 3.1 0.91 9.4 2.1 1.7 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF724 PF05266.9 CCF50412.1 - 1.1 8.8 4.8 0.43 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.7 CCF50412.1 - 2.5 7.3 14.6 1.5 8.1 4.3 2.3 1 1 0 2 2 2 0 PspA/IM30 family zf-U1 PF06220.7 CCF50413.1 - 2.6e-19 68.5 4.2 3.6e-19 68.0 2.9 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CCF50413.1 - 0.02 15.0 2.1 0.036 14.2 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SPOB_a PF14689.1 CCF50413.1 - 0.18 11.4 0.2 0.24 10.9 0.2 1.1 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain WD40 PF00400.27 CCF50414.1 - 5.9e-09 35.4 0.7 0.01 15.6 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Aldedh PF00171.17 CCF50415.1 - 1.1e-158 528.4 1.9 1.2e-158 528.2 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCF50415.1 - 0.021 14.0 0.0 0.079 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Mmp37 PF09139.6 CCF50417.1 - 1.5e-105 352.9 0.0 1.8e-105 352.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Myosin_tail_1 PF01576.14 CCF50418.1 - 0.00099 16.9 23.2 0.00099 16.9 16.1 1.9 2 0 0 2 2 2 1 Myosin tail HALZ PF02183.13 CCF50418.1 - 0.0054 16.4 1.2 0.0054 16.4 0.8 3.7 3 0 0 3 3 3 1 Homeobox associated leucine zipper DivIVA PF05103.8 CCF50418.1 - 1 9.4 16.2 0.89 9.6 0.1 3.2 2 1 1 3 3 3 0 DivIVA protein Baculo_PEP_C PF04513.7 CCF50418.1 - 3.6 7.4 12.4 0.5 10.1 0.1 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.4 CCF50418.1 - 4.7 7.2 4.3 21 5.1 3.0 2.2 1 0 0 1 1 1 0 Haemolysin XhlA NPV_P10 PF05531.7 CCF50418.1 - 8.8 6.6 9.9 1.9 8.7 0.9 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein adh_short PF00106.20 CCF50419.1 - 2.4e-13 50.3 0.0 3.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CCF50419.1 - 2.6e-06 27.0 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCF50419.1 - 2.4e-05 24.0 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF50419.1 - 0.00097 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CCF50419.1 - 0.034 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4499 PF14934.1 CCF50420.1 - 0.014 15.3 0.2 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Yip1 PF04893.12 CCF50420.1 - 0.091 12.2 1.1 0.12 11.8 0.8 1.2 1 0 0 1 1 1 0 Yip1 domain DUF997 PF06196.7 CCF50420.1 - 0.14 11.7 1.8 0.16 11.4 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF997) HsbA PF12296.3 CCF50421.1 - 7.1e-15 54.9 7.1 1.3e-14 54.1 4.9 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A HR1 PF02185.11 CCF50421.1 - 0.15 11.8 0.6 3.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat Abhydrolase_3 PF07859.8 CCF50422.1 - 3.1e-49 167.4 0.0 3.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCF50422.1 - 1.1e-05 24.3 1.1 4.2e-05 22.4 0.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CCF50422.1 - 0.00048 19.4 0.1 0.056 12.6 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 CCF50422.1 - 0.00054 18.5 0.0 0.011 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 CCF50422.1 - 0.0028 17.4 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 CCF50422.1 - 0.062 12.6 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 CCF50422.1 - 0.072 12.3 0.0 6 6.0 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family ERG4_ERG24 PF01222.12 CCF50424.1 - 6.7e-142 473.0 9.2 7.9e-142 472.7 6.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCF50424.1 - 4e-07 29.5 0.3 1.1e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCF50424.1 - 0.00023 21.2 0.0 0.00023 21.2 0.0 2.8 3 1 1 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.9 CCF50424.1 - 0.029 14.5 0.0 0.099 12.8 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2012 PF09430.5 CCF50425.1 - 6e-36 122.9 0.0 8.5e-36 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 CCF50425.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Atx10homo_assoc PF09759.4 CCF50426.1 - 8.2e-22 76.8 0.9 8.2e-19 67.2 0.0 3.7 3 1 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain PAN_4 PF14295.1 CCF50427.1 - 0.0008 19.0 0.6 0.0041 16.7 0.4 2.2 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CCF50427.1 - 0.071 12.8 0.3 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 PAN domain Glyco_trans_2_3 PF13632.1 CCF50430.1 - 8.9e-47 159.2 4.8 8.9e-47 159.2 3.4 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF50430.1 - 8.8e-09 35.4 0.4 4.3e-07 29.9 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCF50430.1 - 0.00061 19.5 0.0 0.038 13.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCF50430.1 - 0.0039 16.4 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 CCF50431.1 - 4.5e-17 61.9 1.1 1.4e-16 60.3 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF2404 PF10296.4 CCF50432.1 - 3.3e-07 30.3 0.0 6.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Mcm10 PF09332.6 CCF50432.1 - 0.073 12.4 0.5 0.16 11.2 0.4 1.5 1 0 0 1 1 1 0 Mcm10 replication factor Cyt-b5 PF00173.23 CCF50433.1 - 1e-21 76.4 2.7 1.1e-21 76.4 0.2 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCF50433.1 - 1.2e-09 38.5 20.4 4e-09 36.8 12.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Lactamase_B_2 PF12706.2 CCF50434.1 - 2.5e-30 105.4 0.0 1.2e-29 103.2 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCF50434.1 - 6e-14 51.2 0.0 1.7e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CCF50434.1 - 1.9e-06 27.6 1.4 4.5e-06 26.4 1.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1682 PF07946.9 CCF50437.1 - 2.2 7.0 15.3 0.041 12.7 5.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Rot1 PF10681.4 CCF50438.1 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Ni_hydr_CYTB PF01292.15 CCF50438.1 - 0.11 11.8 2.8 0.42 9.9 1.9 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 PSII_Ycf12 PF05969.6 CCF50438.1 - 0.94 9.1 4.9 0.26 10.9 0.8 2.1 2 0 0 2 2 2 0 Photosystem II complex subunit Ycf12 Dynamin_N PF00350.18 CCF50439.1 - 9.6e-17 61.3 0.0 8.3e-16 58.2 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 CCF50439.1 - 0.036 14.5 0.1 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 CCF50439.1 - 0.1 12.5 0.4 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CCF50439.1 - 0.15 12.0 0.0 21 5.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase RCC1_2 PF13540.1 CCF50440.1 - 3e-18 64.9 13.2 0.0001 21.8 0.1 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCF50440.1 - 1.3e-12 47.7 20.8 0.0003 20.9 0.0 7.7 7 3 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat KH_1 PF00013.24 CCF50441.1 - 1.9e-38 129.8 9.2 1.3e-16 60.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCF50441.1 - 8.2e-30 101.9 10.6 4.4e-10 38.9 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCF50441.1 - 1.2e-11 44.0 5.7 0.0013 18.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCF50441.1 - 2.3e-08 33.5 0.7 0.093 12.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CCF50441.1 - 0.0029 17.3 3.2 0.4 10.5 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain dUTPase PF00692.14 CCF50441.1 - 0.067 12.6 0.4 0.75 9.2 0.0 2.6 3 0 0 3 3 3 0 dUTPase Menin PF05053.8 CCF50441.1 - 1.7 6.7 9.9 3.7 5.5 6.9 1.5 1 0 0 1 1 1 0 Menin DUF202 PF02656.10 CCF50442.1 - 1.6e-15 57.0 1.7 3.1e-15 56.1 0.3 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) Spore_coat_CotO PF14153.1 CCF50443.1 - 0.00032 20.1 9.9 0.00032 20.1 6.8 2.0 2 0 0 2 2 2 1 Spore coat protein CotO Ycf1 PF05758.7 CCF50443.1 - 0.014 13.1 6.5 0.018 12.7 4.5 1.2 1 0 0 1 1 1 0 Ycf1 DBD_Tnp_Mut PF03108.10 CCF50443.1 - 0.06 12.9 0.0 7.5 6.2 0.0 2.3 2 0 0 2 2 2 0 MuDR family transposase NARP1 PF12569.3 CCF50443.1 - 0.071 11.8 10.0 0.15 10.7 6.9 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TFIIA PF03153.8 CCF50443.1 - 0.65 9.8 50.1 0.18 11.6 22.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCHC PF00098.18 CCF50443.1 - 2.6 8.1 10.1 0.081 12.8 1.9 2.2 2 0 0 2 2 2 0 Zinc knuckle PPP4R2 PF09184.6 CCF50443.1 - 3.8 6.9 15.8 8.6 5.8 10.9 1.5 1 0 0 1 1 1 0 PPP4R2 PAT1 PF09770.4 CCF50443.1 - 3.9 5.5 63.9 0.11 10.7 33.9 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 CCF50443.1 - 4 5.0 8.9 5.6 4.5 6.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-3_zeta PF05091.7 CCF50443.1 - 6.9 5.1 25.6 0.64 8.5 13.7 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SelP_N PF04592.9 CCF50443.1 - 7.9 5.7 25.6 0.17 11.2 12.4 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Acyltransferase PF01553.16 CCF50444.1 - 0.0023 17.3 0.0 0.048 13.0 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase Fringe PF02434.11 CCF50445.1 - 2.4e-05 23.7 0.3 5.7e-05 22.4 0.2 1.5 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 CCF50445.1 - 0.00082 19.0 1.2 0.0019 17.8 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CCF50445.1 - 0.02 14.6 0.1 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 PAN domain DUF3357 PF11837.3 CCF50445.1 - 0.059 13.2 0.1 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Pax2_C PF12403.3 CCF50446.1 - 0.084 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Paired-box protein 2 C terminal DnaJ PF00226.26 CCF50447.1 - 5.6e-20 70.8 0.7 9.5e-20 70.1 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_YMGG PF13441.1 CCF50447.1 - 0.0072 15.8 5.1 0.013 14.9 3.5 1.4 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF456 PF04306.8 CCF50447.1 - 0.044 13.8 1.2 0.063 13.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 CCF50447.1 - 0.095 12.3 7.2 0.18 11.4 5.0 1.5 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CCF50447.1 - 0.24 11.1 8.6 0.47 10.1 0.8 2.2 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 CCF50447.1 - 0.31 10.6 2.0 0.36 10.4 0.4 1.8 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 CCF50447.1 - 0.33 11.1 4.5 0.56 10.3 3.1 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide BPL_LplA_LipB PF03099.14 CCF50449.1 - 1.6e-15 57.2 0.0 2.7e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Opy2 PF09463.5 CCF50450.1 - 0.018 15.1 18.3 0.03 14.4 12.7 1.4 1 0 0 1 1 1 0 Opy2 protein p450 PF00067.17 CCF50451.1 - 4.2e-74 249.7 0.0 1.3e-73 248.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.10 CCF50452.1 - 2.6e-129 431.6 40.4 3e-129 431.4 28.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1338 PF07063.8 CCF50453.1 - 1.8e-79 266.9 0.0 2.4e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Aldedh PF00171.17 CCF50454.1 - 2e-118 395.6 0.0 2.3e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF50454.1 - 0.034 12.8 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Surp PF01805.15 CCF50455.1 - 3.9e-08 32.8 0.1 7.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 CCF50455.1 - 1.7e-06 27.9 0.0 3.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50455.1 - 3.9e-05 23.2 0.0 0.0001 21.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rer1 PF03248.8 CCF50456.1 - 3.5e-83 277.5 0.0 4e-83 277.3 0.0 1.0 1 0 0 1 1 1 1 Rer1 family IgaA PF07095.6 CCF50456.1 - 0.2 9.3 0.3 0.27 8.9 0.2 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF4131 PF13567.1 CCF50456.1 - 0.8 9.0 4.8 0.92 8.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pyr_redox_2 PF07992.9 CCF50457.1 - 1.9e-19 70.3 0.0 3.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF50457.1 - 7.2e-13 48.7 0.0 1.6e-08 34.8 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 CCF50457.1 - 1.1e-11 43.0 3.1 4.6e-06 25.5 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CCF50457.1 - 4.5e-11 42.7 0.2 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCF50457.1 - 1e-08 34.3 2.4 0.00021 20.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CCF50457.1 - 1.3e-08 33.8 2.5 0.0028 16.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CCF50457.1 - 1.6e-06 27.6 2.2 0.0021 17.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair Pyr_redox_3 PF13738.1 CCF50457.1 - 0.002 18.1 0.0 0.86 9.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF50457.1 - 0.024 14.4 0.0 8.9 6.0 0.0 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CCF50457.1 - 0.079 13.2 0.3 0.75 10.0 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF2611 PF11022.3 CCF50458.1 - 4.8e-17 61.7 4.3 2.2e-16 59.7 3.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Yae1_N PF09811.4 CCF50459.1 - 9.6e-12 44.2 3.8 1.6e-11 43.5 2.6 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Pentapeptide PF00805.17 CCF50459.1 - 0.01 15.0 1.2 0.019 14.2 0.8 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) TFIIA_gamma_N PF02268.11 CCF50460.1 - 5.4e-26 89.9 0.1 7.8e-26 89.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 CCF50460.1 - 1.7e-23 82.1 0.9 2.3e-23 81.7 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2841 PF11001.3 CCF50461.1 - 7.8e-37 125.9 0.3 1.2e-36 125.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Stress-antifung PF01657.12 CCF50461.1 - 0.18 12.1 2.6 0.34 11.2 0.0 2.5 3 0 0 3 3 3 0 Salt stress response/antifungal DUF1908 PF08926.6 CCF50461.1 - 1.3 7.6 4.5 2.7 6.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) CRAL_TRIO PF00650.15 CCF50462.1 - 8.8e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain SNF2_N PF00176.18 CCF50463.1 - 1.3e-62 211.3 0.0 2e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF50463.1 - 5.6e-13 48.5 0.0 1.8e-12 46.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF50463.1 - 3.9e-09 36.2 0.0 8.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCF50463.1 - 1.7e-07 31.2 0.2 6.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CCF50463.1 - 7.5e-06 24.9 0.2 1.6e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2764 PF10962.3 CCF50463.1 - 0.0058 15.9 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2764) DUF2075 PF09848.4 CCF50463.1 - 0.014 14.3 0.0 0.035 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TusA PF01206.12 CCF50463.1 - 0.025 14.1 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Sulfurtransferase TusA PH PF00169.24 CCF50465.1 - 8.7e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF2457 PF10446.4 CCF50465.1 - 0.011 14.5 6.5 0.02 13.6 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RICTOR_M PF14666.1 CCF50465.1 - 0.061 12.3 0.3 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain Glycos_transf_4 PF00953.16 CCF50466.1 - 2.1e-33 115.3 5.9 2.1e-33 115.3 4.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 TFIIE_alpha PF02002.12 CCF50467.1 - 1.2e-09 37.5 0.6 2.3e-09 36.7 0.4 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Zn_Tnp_IS1595 PF12760.2 CCF50467.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DASH_Dam1 PF08653.5 CCF50467.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 Cupin_8 PF13621.1 CCF50468.1 - 1.1e-50 172.5 1.8 1.3e-49 169.0 1.3 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCF50468.1 - 0.0016 17.7 0.0 0.0077 15.5 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 CCF50468.1 - 0.19 11.9 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 JmjC domain, hydroxylase Zn_clus PF00172.13 CCF50469.1 - 7.6e-07 28.9 11.8 7.6e-07 28.9 8.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PKD_channel PF08016.7 CCF50471.1 - 0.036 12.4 12.2 0.57 8.5 7.8 2.6 2 1 0 2 2 2 0 Polycystin cation channel Ion_trans PF00520.26 CCF50471.1 - 1.5 8.0 21.4 52 3.0 14.9 2.9 1 1 0 1 1 1 0 Ion transport protein UQ_con PF00179.21 CCF50472.1 - 3.1e-46 156.2 0.0 3.7e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF50472.1 - 0.0013 18.4 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCF50472.1 - 0.009 15.6 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CCF50472.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain WH1 PF00568.18 CCF50473.1 - 1.5e-25 89.0 0.0 2.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 CCF50473.1 - 3.1e-08 33.8 0.2 3.1e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.15 CCF50473.1 - 0.007 15.9 0.9 0.031 13.8 0.6 2.2 1 1 0 1 1 1 1 WH2 motif AA_permease PF00324.16 CCF50474.1 - 2.4e-115 385.5 41.2 2.8e-115 385.4 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF50474.1 - 4.2e-36 124.3 45.9 5.2e-36 124.0 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF543 PF04418.7 CCF50475.1 - 6.9e-29 99.6 0.2 6.9e-29 99.6 0.1 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF543) DUF883 PF05957.8 CCF50475.1 - 0.00033 20.9 5.6 0.28 11.6 2.9 2.9 2 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) DUF4661 PF15576.1 CCF50475.1 - 0.06 12.9 0.8 0.088 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) RepB PF07506.6 CCF50475.1 - 0.094 12.5 2.3 0.12 12.2 1.6 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF4386 PF14329.1 CCF50475.1 - 0.1 12.0 0.1 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DivIVA PF05103.8 CCF50475.1 - 1 9.4 6.6 1.4 8.9 4.6 1.3 1 0 0 1 1 1 0 DivIVA protein YtxH PF12732.2 CCF50475.1 - 6.5 7.2 9.0 0.43 10.9 2.6 1.8 2 0 0 2 2 2 0 YtxH-like protein PNRC PF15365.1 CCF50476.1 - 0.016 15.2 0.6 0.016 15.2 0.4 1.7 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator DUF4536 PF15055.1 CCF50476.1 - 4.6 7.3 7.6 0.43 10.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Peroxidase_2 PF01328.12 CCF50478.1 - 1.5e-12 46.8 0.0 2.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 RNase_T PF00929.19 CCF50479.1 - 1.6e-20 74.0 0.3 3.1e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCF50479.1 - 0.015 14.7 0.0 0.048 13.1 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease PINIT PF14324.1 CCF50480.1 - 7.1e-29 100.7 0.3 1.2e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CCF50480.1 - 9.8e-20 69.8 5.4 1.7e-19 69.0 3.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCF50480.1 - 2.9e-05 23.4 1.4 5.8e-05 22.5 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 CCF50480.1 - 0.16 11.5 0.1 0.43 10.1 0.0 1.8 1 0 0 1 1 1 0 SAP domain LZ_Tnp_IS66 PF13007.2 CCF50480.1 - 3.7 8.2 11.4 16 6.2 0.0 3.5 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Whi5 PF08528.6 CCF50481.1 - 3.6e-05 23.2 0.0 7.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Whi5 like Bac_Ubq_Cox PF01654.12 CCF50481.1 - 0.15 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase zf-H2C2_2 PF13465.1 CCF50482.1 - 1.9e-08 34.1 0.6 1.9e-08 34.1 0.4 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCF50482.1 - 1e-06 28.6 11.1 8.5e-06 25.8 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCF50482.1 - 7.2e-05 22.5 4.5 0.17 11.8 0.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCF50482.1 - 0.00095 19.3 0.4 0.00095 19.3 0.3 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger Tmemb_cc2 PF10267.4 CCF50482.1 - 0.0039 15.8 0.8 0.0039 15.8 0.6 1.7 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein zf-met PF12874.2 CCF50482.1 - 0.091 12.9 3.1 5.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DFP PF04127.10 CCF50483.1 - 4.6e-18 65.4 0.0 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AA_permease PF00324.16 CCF50484.1 - 6.7e-110 367.6 41.1 8.4e-110 367.3 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF50484.1 - 1e-33 116.5 44.2 1.8e-33 115.7 30.6 1.4 1 1 0 1 1 1 1 Amino acid permease DSPc PF00782.15 CCF50485.1 - 1.3e-18 66.8 1.9 1.4e-15 57.0 0.4 3.1 3 1 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF50485.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TT_ORF2 PF02957.10 CCF50486.1 - 0.042 14.5 2.8 0.057 14.1 2.0 1.3 1 0 0 1 1 1 0 TT viral ORF2 RNB PF00773.14 CCF50487.1 - 7e-91 304.8 0.0 1e-90 304.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 CCF50487.1 - 2.1e-09 37.5 2.2 1.2e-08 35.1 1.5 2.3 1 1 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CCF50487.1 - 0.015 14.7 0.1 0.054 13.0 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2514 PF10721.4 CCF50490.1 - 0.18 11.5 6.6 0.37 10.4 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GATA PF00320.22 CCF50492.1 - 1e-28 98.3 14.4 5.9e-15 54.3 2.5 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 CCF50492.1 - 2.3e-09 36.6 0.8 5.5e-09 35.4 0.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CCF50492.1 - 0.00028 20.1 3.4 0.1 11.9 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 CCF50492.1 - 0.0081 15.9 4.2 0.25 11.1 3.2 2.6 1 1 1 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 CCF50492.1 - 0.082 12.4 4.6 0.14 11.7 0.1 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.5 CCF50492.1 - 0.11 12.4 1.2 11 6.0 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain RRN7 PF11781.3 CCF50492.1 - 0.38 10.3 4.8 1.2 8.6 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 eIF-5_eIF-2B PF01873.12 CCF50492.1 - 0.42 10.2 4.0 8.5 6.0 0.2 2.7 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-ribbon_3 PF13248.1 CCF50492.1 - 6.6 6.0 9.9 2.5 7.4 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbon domain TRAPPC-Trs85 PF12739.2 CCF50493.1 - 1.9e-94 316.6 0.4 2.8e-94 316.1 0.3 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Gryzun PF07919.7 CCF50493.1 - 3.7e-08 32.1 0.0 6.3e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi TRAPPC9-Trs120 PF08626.6 CCF50493.1 - 0.00031 18.2 0.0 0.00049 17.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 CCF50493.1 - 0.085 12.5 5.1 0.21 11.2 0.0 3.1 3 0 0 3 3 3 0 TPR repeat Transglut_C PF00927.17 CCF50493.1 - 0.091 12.8 0.0 48 4.0 0.0 3.9 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain SURF4 PF02077.10 CCF50494.1 - 1e-93 313.6 5.9 1.1e-93 313.4 4.1 1.0 1 0 0 1 1 1 1 SURF4 family CbtB PF09489.5 CCF50494.1 - 0.46 10.4 2.1 12 5.8 0.1 2.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) HR_lesion PF05514.6 CCF50494.1 - 1.7 8.5 12.0 0.11 12.3 1.6 3.1 2 2 2 4 4 4 0 HR-like lesion-inducing Fungal_trans PF04082.13 CCF50496.1 - 3.4e-19 68.7 0.1 3.4e-19 68.7 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF50496.1 - 1.9e-07 30.8 8.9 3.8e-07 29.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 CCF50496.1 - 0.27 10.7 4.0 0.53 9.8 2.8 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 PBP1_TM PF14812.1 CCF50496.1 - 1 9.7 7.5 3 8.1 5.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_47 PF01532.15 CCF50497.1 - 5.3e-150 500.0 0.0 7.2e-150 499.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MutS_III PF05192.13 CCF50498.1 - 0.076 12.7 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 MutS domain III Mito_carr PF00153.22 CCF50499.1 - 1.3e-53 178.6 3.4 4.9e-18 64.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CCF50500.1 - 2.9e-68 229.8 0.1 1.6e-67 227.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50500.1 - 3.9e-49 167.0 0.1 1.2e-48 165.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50500.1 - 0.00062 18.8 0.0 0.0022 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Spt20 PF12090.3 CCF50500.1 - 0.21 10.8 15.7 2.7 7.3 6.6 2.4 2 0 0 2 2 2 0 Spt20 family zf-DHHC PF01529.15 CCF50500.1 - 0.7 9.2 3.3 0.72 9.2 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4175 PF13779.1 CCF50500.1 - 0.84 7.2 48.0 0.42 8.2 18.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FimP PF09766.4 CCF50500.1 - 2.7 6.9 27.6 4.2 6.3 11.3 2.4 2 0 0 2 2 2 0 Fms-interacting protein RR_TM4-6 PF06459.7 CCF50500.1 - 3.2 7.5 19.0 2.6 7.8 8.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CCF50500.1 - 4.4 5.3 67.5 7.7 4.5 46.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CCF50500.1 - 6.1 7.1 9.5 0.58 10.4 1.1 2.8 3 0 0 3 3 3 0 AAA domain COG2 PF06148.6 CCF50501.1 - 1.2e-35 122.2 0.4 1.2e-35 122.2 0.3 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CCF50501.1 - 4.3e-07 30.0 0.2 1.8e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) adh_short PF00106.20 CCF50502.1 - 4.4e-24 85.2 0.2 5.9e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF50502.1 - 1.1e-14 54.4 0.2 1.9e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCF50502.1 - 2.6e-07 30.8 0.2 6e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 CCF50502.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 CCF50502.1 - 0.0001 21.4 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 CCF50502.1 - 0.003 17.0 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 CCF50502.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_trans_4_4 PF13579.1 CCF50502.1 - 0.013 15.6 0.1 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Polysacc_synt_2 PF02719.10 CCF50502.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 CCF50502.1 - 0.018 15.4 0.4 0.046 14.1 0.0 1.9 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CCF50502.1 - 0.018 15.2 0.1 0.037 14.2 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CCF50502.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CCF50502.1 - 0.03 14.0 1.6 0.098 12.4 0.2 2.2 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 CCF50502.1 - 0.037 13.0 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase YjeF_N PF03853.10 CCF50502.1 - 0.067 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus ApbA PF02558.11 CCF50502.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA La PF05383.12 CCF50503.1 - 7.3e-19 67.3 0.3 7.2e-18 64.1 0.0 2.6 3 0 0 3 3 3 1 La domain RRM_1 PF00076.17 CCF50503.1 - 1.9e-07 30.5 0.3 5.4e-07 29.1 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50503.1 - 1.6e-05 24.7 0.2 5.4e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF50503.1 - 4.2e-05 23.3 0.2 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 CCF50503.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.7 CCF50503.1 - 0.051 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain MFS_1 PF07690.11 CCF50504.1 - 0.019 13.7 0.5 0.026 13.2 0.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Pro_isomerase PF00160.16 CCF50505.1 - 3.1e-50 170.4 0.2 3.5e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank PF00023.25 CCF50506.1 - 1.7e-21 74.8 4.9 9.2e-08 31.5 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 CCF50506.1 - 2.3e-19 69.5 0.9 7.7e-14 51.7 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCF50506.1 - 4.4e-19 68.4 2.3 6.1e-13 48.8 0.6 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCF50506.1 - 7.8e-16 57.7 5.0 2.1e-08 34.1 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF50506.1 - 5.7e-15 53.9 2.3 0.00058 19.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat IDO PF01231.13 CCF50507.1 - 4.3e-39 134.1 0.0 6.3e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Chorismate_bind PF00425.13 CCF50508.1 - 4.7e-76 255.5 0.0 7.6e-76 254.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CCF50508.1 - 2e-32 112.2 0.0 5.3e-22 78.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CCF50508.1 - 2.5e-13 50.2 0.0 1.1e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CCF50508.1 - 3e-07 30.1 0.0 2.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 Foie-gras_1 PF11817.3 CCF50509.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 Desmo_N PF06771.6 CCF50509.1 - 0.13 12.1 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus COX5A PF02284.11 CCF50509.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Zn_clus PF00172.13 CCF50510.1 - 1.5e-09 37.5 11.4 2.4e-09 36.9 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.17 CCF50516.1 - 2.9e-06 26.7 0.0 1.9e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase BolA PF01722.13 CCF50517.1 - 1.6e-19 69.5 0.0 2.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein UvrD-helicase PF00580.16 CCF50518.1 - 7e-15 55.1 0.0 1.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCF50518.1 - 7.3e-12 45.3 0.0 1.8e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 CCF50518.1 - 4.2e-11 42.9 0.0 7.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CCF50518.1 - 1.7e-09 37.5 0.1 0.0034 16.9 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CCF50518.1 - 1.3e-07 31.3 0.0 0.00057 19.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCF50518.1 - 1.4e-06 27.9 1.1 6.7e-06 25.7 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 CCF50518.1 - 0.00058 20.0 0.5 1.5 8.9 0.0 3.0 2 1 0 3 3 3 2 AAA domain PhoH PF02562.11 CCF50518.1 - 0.0013 18.0 0.0 0.066 12.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Med13_N PF11597.3 CCF50519.1 - 0.073 11.7 0.1 0.071 11.7 0.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Cyclin_N PF00134.18 CCF50520.1 - 1.6e-44 150.5 0.3 1e-42 144.7 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCF50520.1 - 6.4e-32 109.9 0.2 6.4e-32 109.9 0.2 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain JAB PF01398.16 CCF50521.1 - 9.9e-29 99.3 0.1 1.4e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCF50521.1 - 6.1e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Phage_integ_N PF09003.5 CCF50521.1 - 0.056 13.1 0.8 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 Bacteriophage lambda integrase, N-terminal domain UPF0172 PF03665.8 CCF50521.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) PTPlike_phytase PF14566.1 CCF50522.1 - 0.00022 21.3 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 CCF50522.1 - 0.00027 20.5 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCF50522.1 - 0.0044 17.2 0.1 0.033 14.4 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCF50522.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aldedh PF00171.17 CCF50523.1 - 1.7e-122 409.0 0.0 2.1e-122 408.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Viral_env_E26 PF11050.3 CCF50523.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Virus envelope protein E26 WD40 PF00400.27 CCF50524.1 - 1.5e-29 100.7 7.1 1.8e-06 27.5 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCF50524.1 - 0.032 13.7 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pyr_redox_2 PF07992.9 CCF50525.1 - 7.4e-29 101.0 0.0 9.3e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF50525.1 - 8.5e-19 67.7 0.2 1.9e-15 57.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF50525.1 - 8.9e-09 35.6 0.1 0.00072 19.6 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF50525.1 - 5e-06 25.7 0.1 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 CCF50525.1 - 7.5e-06 25.8 0.1 0.00043 20.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 CCF50525.1 - 2.2e-05 23.7 2.1 0.071 12.1 0.0 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCF50525.1 - 0.00035 19.5 2.5 0.0062 15.4 0.1 2.6 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 CCF50525.1 - 0.00042 19.3 0.1 0.0048 15.8 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCF50525.1 - 0.00047 19.3 1.5 0.056 12.4 0.1 2.4 2 1 1 3 3 3 2 FAD binding domain GIDA PF01134.17 CCF50525.1 - 0.00076 18.4 5.3 0.0055 15.6 0.1 3.1 4 0 0 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.1 CCF50525.1 - 0.00097 18.1 0.1 0.023 13.6 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CCF50525.1 - 0.00099 19.3 0.9 0.039 14.1 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 CCF50525.1 - 0.0021 16.7 0.0 0.047 12.3 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Shikimate_DH PF01488.15 CCF50525.1 - 0.0041 17.2 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CCF50525.1 - 0.0041 15.6 0.4 0.013 13.9 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DEAD PF00270.24 CCF50526.1 - 1.7e-32 112.2 0.4 9e-32 109.8 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF50526.1 - 7.5e-26 89.8 0.2 1.4e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCF50526.1 - 0.0028 17.6 0.0 0.0063 16.4 0.0 1.6 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.1 CCF50526.1 - 0.12 12.1 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain CDC27 PF09507.5 CCF50527.1 - 1.6e-90 304.4 43.0 6.8e-90 302.3 29.8 1.8 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Gcd10p PF04189.8 CCF50529.1 - 2e-87 293.1 0.2 4.5e-86 288.6 0.0 2.1 2 0 0 2 2 2 1 Gcd10p family Ssu72 PF04722.8 CCF50530.1 - 7.7e-78 260.3 0.0 8.9e-78 260.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 CCF50530.1 - 0.022 15.1 1.8 0.032 14.5 0.2 2.1 3 0 0 3 3 3 0 Low molecular weight phosphotyrosine protein phosphatase Ras PF00071.17 CCF50531.1 - 9.7e-54 181.1 0.0 1.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF50531.1 - 4.3e-15 56.2 0.0 8.1e-15 55.3 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCF50531.1 - 7.3e-07 28.5 0.0 1.5e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF50531.1 - 0.012 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCF50531.1 - 0.061 12.8 0.5 1.4 8.4 0.3 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TPR_16 PF13432.1 CCF50532.1 - 6.7 7.5 10.8 15 6.4 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 CCF50533.1 - 2.5e-42 144.2 0.0 1.9e-41 141.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF50533.1 - 1e-23 82.9 0.1 2.4e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCF50533.1 - 3.2e-05 22.8 0.0 7.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCF50533.1 - 0.00056 19.7 0.4 0.0058 16.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rrp15p PF07890.7 CCF50533.1 - 0.08 12.9 7.9 0.25 11.4 5.5 1.8 1 0 0 1 1 1 0 Rrp15p CMS1 PF14617.1 CCF50533.1 - 4.1 6.3 7.0 0.87 8.6 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Acyl-CoA_dh_1 PF00441.19 CCF50534.1 - 1.2e-33 116.3 0.6 1.6e-33 115.9 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF50534.1 - 1.3e-16 59.8 0.1 2.1e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCF50534.1 - 2.3e-10 41.0 0.2 1.6e-09 38.3 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCF50534.1 - 8.8e-09 35.7 0.2 1.3e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_8 PF01501.15 CCF50535.1 - 1.7e-15 57.0 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CCF50535.1 - 0.036 13.8 0.0 0.068 12.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 CCF50535.1 - 0.094 12.0 0.2 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative SUZ PF12752.2 CCF50536.1 - 9.6e-14 51.6 4.5 9.6e-14 51.6 3.1 4.4 5 0 0 5 5 5 1 SUZ domain R3H PF01424.17 CCF50536.1 - 6.9e-09 35.2 0.3 1.2e-08 34.5 0.2 1.4 1 0 0 1 1 1 1 R3H domain UCH PF00443.24 CCF50537.1 - 4.9e-43 147.1 0.0 7.3e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF50537.1 - 4.4e-11 42.7 0.0 8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2267 PF10025.4 CCF50537.1 - 0.024 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Toxin_8 PF07365.7 CCF50537.1 - 0.18 11.7 1.9 0.6 10.1 1.3 1.9 1 0 0 1 1 1 0 Alpha conotoxin precursor TrbE PF11100.3 CCF50538.1 - 0.28 11.0 1.9 0.48 10.3 1.3 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbE NAD_binding_1 PF00175.16 CCF50539.1 - 2.7e-25 89.0 0.0 4.5e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCF50539.1 - 9.1e-19 67.4 0.0 1.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCF50539.1 - 1.7e-06 28.0 0.0 1.9e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ABC_tran PF00005.22 CCF50540.1 - 2.2e-46 157.5 0.0 3.3e-23 82.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CCF50540.1 - 2.3e-24 85.0 4.1 2.3e-24 85.0 2.9 3.7 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 CCF50540.1 - 4.9e-18 66.1 0.0 0.001 19.1 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CCF50540.1 - 5.9e-12 45.2 0.5 0.00013 21.3 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF50540.1 - 1.6e-08 33.9 0.3 0.0015 18.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCF50540.1 - 4.9e-08 33.8 0.6 0.0098 16.7 0.0 4.2 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 CCF50540.1 - 1.4e-07 31.4 0.0 0.0034 17.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 CCF50540.1 - 1.8e-06 27.5 0.4 0.03 13.7 0.0 4.0 4 0 0 4 4 4 2 AAA-like domain NACHT PF05729.7 CCF50540.1 - 1.9e-06 27.6 0.2 0.0047 16.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 CCF50540.1 - 4.1e-06 26.9 0.2 0.23 11.6 0.0 3.5 4 1 0 4 4 3 2 AAA domain Miro PF08477.8 CCF50540.1 - 4.4e-06 27.1 0.0 0.11 12.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 CCF50540.1 - 5.7e-06 25.8 0.0 0.018 14.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCF50540.1 - 7e-06 25.3 0.0 0.047 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCF50540.1 - 3e-05 24.0 1.8 0.18 11.7 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain MobB PF03205.9 CCF50540.1 - 7.8e-05 22.4 0.0 0.069 12.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCF50540.1 - 9.3e-05 22.4 3.1 0.12 12.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 CCF50540.1 - 0.00012 22.2 0.0 0.26 11.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CCF50540.1 - 0.00017 21.4 0.1 0.3 11.0 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CCF50540.1 - 0.00026 20.9 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCF50540.1 - 0.00033 20.9 0.6 1.5 9.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CCF50540.1 - 0.00055 20.0 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 CCF50540.1 - 0.0012 17.6 0.1 1.6 7.4 0.0 2.7 2 0 0 2 2 2 2 ArgK protein FtsK_SpoIIIE PF01580.13 CCF50540.1 - 0.0029 17.1 0.1 0.35 10.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 CCF50540.1 - 0.0053 17.0 15.3 0.014 15.6 0.0 4.6 4 1 1 5 5 4 1 AAA domain AAA_15 PF13175.1 CCF50540.1 - 0.009 15.0 0.8 8.3 5.3 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain MutS_V PF00488.16 CCF50540.1 - 0.01 15.2 0.1 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 MutS domain V DUF87 PF01935.12 CCF50540.1 - 0.011 15.6 3.5 0.12 12.1 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_33 PF13671.1 CCF50540.1 - 0.036 13.9 7.5 0.26 11.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.18 CCF50540.1 - 0.039 13.7 3.9 0.58 9.9 0.0 3.2 4 0 0 4 4 3 0 Dynamin family NB-ARC PF00931.17 CCF50540.1 - 0.039 12.8 0.1 5.5 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 CCF50540.1 - 0.05 13.0 0.3 9.7 5.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCF50540.1 - 0.058 12.8 0.0 4.7 6.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CCF50540.1 - 0.085 12.5 0.4 16 5.1 0.0 2.9 3 0 0 3 3 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 CCF50540.1 - 0.13 11.8 0.0 2.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 CCF50540.1 - 0.39 10.4 2.7 18 5.0 0.1 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Cyclase PF04199.8 CCF50541.1 - 2.4e-11 43.6 0.2 5.6e-11 42.4 0.1 1.7 1 1 0 1 1 1 1 Putative cyclase Mur_ligase_M PF08245.7 CCF50542.1 - 1.2e-07 32.0 0.0 0.0025 17.8 0.0 2.5 2 0 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.16 CCF50542.1 - 0.0068 16.4 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Chordopox_E11 PF06138.7 CCF50542.1 - 0.2 11.7 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus E11 protein R3H PF01424.17 CCF50544.1 - 5.8e-12 45.1 0.1 1.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 CCF50544.1 - 1.8e-10 40.6 0.0 3.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50544.1 - 1e-08 34.6 0.0 2.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50544.1 - 5.1e-05 23.0 0.0 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2414 PF10309.4 CCF50545.1 - 5.4e-09 35.6 0.0 8.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) ING PF12998.2 CCF50545.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.5 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding BTB PF00651.26 CCF50546.1 - 2e-10 40.6 0.5 0.00034 20.5 0.0 3.7 3 1 0 3 3 3 3 BTB/POZ domain WD40 PF00400.27 CCF50547.1 - 8.1e-47 155.5 3.0 4.3e-10 39.0 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 CCF50547.1 - 8.8e-45 152.3 4.8 8.8e-45 152.3 3.3 4.2 3 1 0 3 3 3 1 Striatin family Nucleoporin_N PF08801.6 CCF50547.1 - 0.0039 16.0 0.6 0.3 9.7 0.0 3.3 3 1 1 4 4 4 1 Nup133 N terminal like Sulfate_transp PF00916.15 CCF50548.1 - 2.7e-42 144.7 2.0 5.6e-42 143.6 1.4 1.6 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 CCF50548.1 - 4.9e-14 51.8 0.0 1.2e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 CCF50548.1 - 3e-08 33.0 0.0 6.2e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain Med26 PF08711.6 CCF50549.1 - 3.7e-07 29.5 0.4 9.5e-07 28.2 0.0 2.0 3 0 0 3 3 3 1 TFIIS helical bundle-like domain DUF1903 PF08991.5 CCF50550.1 - 4.4e-28 97.2 5.5 5.2e-28 97.0 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CCF50550.1 - 0.063 13.2 4.9 0.11 12.5 3.4 1.5 1 0 0 1 1 1 0 CHCH domain Abhydrolase_5 PF12695.2 CCF50552.1 - 2.6e-06 27.2 0.0 8.8e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CCF50552.1 - 3.9e-06 25.8 0.0 5.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF50552.1 - 0.001 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold R3H PF01424.17 CCF50553.1 - 1.5e-12 46.9 0.1 3e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CCF50553.1 - 5.8e-06 26.1 33.6 2.5e-05 24.0 9.3 13.9 14 1 0 14 14 14 7 NF-X1 type zinc finger HSP70 PF00012.15 CCF50554.1 - 2.5e-267 887.7 8.2 2.8e-267 887.5 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCF50554.1 - 5.8e-16 57.9 0.2 3.5e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CCF50554.1 - 0.0014 17.7 0.1 0.0079 15.3 0.0 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 CCF50554.1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CCF50554.1 - 0.0096 15.7 2.3 0.23 11.2 0.0 3.3 3 2 0 3 3 3 1 Cell division protein FtsA DDR PF08841.5 CCF50554.1 - 0.037 12.8 0.2 0.22 10.3 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FlxA PF14282.1 CCF50554.1 - 5.5 6.9 12.8 0.23 11.4 0.5 2.4 1 1 1 2 2 2 0 FlxA-like protein WD40 PF00400.27 CCF50555.1 - 5.8e-21 73.5 7.0 3.1e-05 23.6 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 CCF50555.1 - 0.02 14.8 2.1 0.059 13.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) eIF2A PF08662.6 CCF50555.1 - 0.073 12.7 0.0 1.1 8.9 0.0 2.3 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A SAGA-Tad1 PF12767.2 CCF50556.1 - 3e-56 190.9 2.6 4.8e-56 190.2 0.2 2.0 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Dak1 PF02733.12 CCF50557.1 - 0.1 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Dak1 domain BRCT PF00533.21 CCF50558.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 CCF50560.1 - 8.9e-43 146.2 0.3 2.1e-23 82.8 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50560.1 - 4.4e-12 45.6 0.4 2.7e-09 36.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCF50560.1 - 0.21 10.3 0.1 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CCF50560.1 - 0.29 10.4 0.1 0.52 9.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family tRNA-synt_1b PF00579.20 CCF50561.1 - 7.3e-23 81.1 0.0 7e-22 77.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) LSM PF01423.17 CCF50562.1 - 1.7e-11 43.4 0.1 2.5e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCF50562.1 - 5.2e-05 23.0 0.1 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 CCF50562.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) TAF PF02969.12 CCF50563.1 - 6.4e-26 90.1 0.7 1.3e-25 89.1 0.5 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 CCF50563.1 - 1.3e-12 47.6 0.1 3.9e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 CCF50563.1 - 9.9e-06 25.5 0.7 2.3e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 CCF50563.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Tubulin PF00091.20 CCF50564.1 - 1.7e-75 253.5 0.0 3.1e-75 252.7 0.0 1.4 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCF50564.1 - 1.1e-43 148.2 0.0 2.1e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCF50564.1 - 3.4e-07 30.3 0.0 6.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCF50564.1 - 0.0076 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Fibrillarin PF01269.12 CCF50565.1 - 8e-108 358.6 0.0 9.9e-108 358.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CCF50565.1 - 9.8e-06 25.2 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CCF50565.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCF50565.1 - 0.053 13.0 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Avl9 PF09794.4 CCF50566.1 - 2.8e-140 467.1 0.0 3.5e-140 466.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 CCF50566.1 - 2.5e-10 40.0 0.1 0.00054 19.3 0.0 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 CCF50566.1 - 1.5e-09 37.5 0.0 9.8e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 CCF50566.1 - 8.7e-05 22.5 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking uDENN PF03456.13 CCF50566.1 - 0.016 15.1 0.1 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 uDENN domain Mito_fiss_reg PF05308.6 CCF50566.1 - 2.7 7.2 7.2 4 6.7 4.7 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator Thaumatin PF00314.12 CCF50568.1 - 0.00017 21.1 1.3 0.00038 20.0 0.3 1.9 1 1 0 1 1 1 1 Thaumatin family Phage-tail_2 PF09096.5 CCF50568.1 - 0.062 12.9 0.5 0.083 12.5 0.3 1.1 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 DUF4399 PF14347.1 CCF50568.1 - 0.094 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) CENP-H PF05837.7 CCF50569.1 - 2e-05 24.7 5.5 2e-05 24.7 3.8 3.5 2 2 1 3 3 3 1 Centromere protein H (CENP-H) NOA36 PF06524.7 CCF50569.1 - 1.5 8.0 5.4 2.5 7.2 3.7 1.5 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 CCF50569.1 - 6 6.3 12.3 3.3 7.1 7.2 1.7 2 0 0 2 2 2 0 Nucleoplasmin PIP5K PF01504.13 CCF50570.1 - 6.9e-84 280.8 0.0 9.7e-84 280.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ras PF00071.17 CCF50571.1 - 3.1e-31 107.9 0.0 1.1e-28 99.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCF50571.1 - 2.5e-13 50.5 0.0 5.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF50571.1 - 1.7e-06 27.4 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF50571.1 - 0.0032 16.6 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF50571.1 - 0.0077 15.6 0.0 0.62 9.4 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF50571.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CCF50571.1 - 0.076 12.5 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glucosamine_iso PF01182.15 CCF50572.1 - 9.6e-66 221.3 0.0 1.1e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Na_H_Exchanger PF00999.16 CCF50573.1 - 1.3e-61 208.2 35.7 2.1e-61 207.5 24.7 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nic96 PF04097.9 CCF50574.1 - 2.8e-187 623.6 0.3 3.7e-187 623.2 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Cation_efflux PF01545.16 CCF50575.1 - 7e-32 110.6 3.2 9.1e-32 110.2 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family tRNA-synt_2b PF00587.20 CCF50576.1 - 1.5e-44 151.6 0.0 2.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF50576.1 - 9.1e-11 41.5 0.2 2e-10 40.4 0.2 1.6 1 1 0 1 1 1 1 Anticodon binding domain RNA12 PF10443.4 CCF50577.1 - 1e-146 488.8 0.5 1.4e-146 488.4 0.3 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 CCF50577.1 - 6.5e-05 22.7 0.2 0.00023 20.9 0.0 1.9 2 0 0 2 2 2 1 Archaeal ATPase RRM_1 PF00076.17 CCF50577.1 - 0.00032 20.2 0.1 0.004 16.7 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 CCF50577.1 - 0.0013 18.7 0.3 0.006 16.5 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCF50577.1 - 0.0018 18.1 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RRM_5 PF13893.1 CCF50577.1 - 0.0025 17.6 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NB-ARC PF00931.17 CCF50577.1 - 0.079 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RRM_6 PF14259.1 CCF50577.1 - 0.16 12.0 0.0 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) JTB PF05439.7 CCF50579.1 - 0.0094 15.7 0.5 0.016 15.0 0.0 1.6 1 1 1 2 2 2 1 Jumping translocation breakpoint protein (JTB) Mito_carr PF00153.22 CCF50580.1 - 0.00029 20.4 0.1 0.0081 15.8 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial carrier protein Clathrin PF00637.15 CCF50581.1 - 9e-16 57.7 0.0 0.00026 20.6 0.0 3.4 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-RING_5 PF14634.1 CCF50581.1 - 0.12 12.0 5.3 0.23 11.2 3.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCF50581.1 - 4.7 7.3 5.8 9.5 6.3 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF50581.1 - 8.9 6.2 7.2 23 4.9 5.0 1.7 1 0 0 1 1 1 0 Ring finger domain GRA6 PF05084.8 CCF50584.1 - 2.7 7.4 7.8 4.2 6.8 5.4 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) RAP1 PF07218.6 CCF50584.1 - 5.8 4.8 14.5 7.3 4.5 10.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOR_SNZ PF01680.12 CCF50585.1 - 2e-112 373.8 4.7 3.2e-112 373.1 3.3 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CCF50585.1 - 1.1e-07 31.2 3.0 5.9e-06 25.5 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 CCF50585.1 - 0.004 16.1 0.2 0.083 11.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 CCF50585.1 - 0.0081 15.2 0.0 0.037 13.0 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.10 CCF50585.1 - 0.019 14.1 2.8 0.021 14.0 0.1 2.2 2 1 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.12 CCF50585.1 - 0.042 12.6 0.2 0.87 8.3 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CCF50585.1 - 0.052 12.8 0.1 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2267 PF10025.4 CCF50585.1 - 0.074 13.1 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) RdRP_3 PF00998.18 CCF50585.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase UCR_TM PF02921.9 CCF50586.1 - 3.8e-20 71.8 1.3 7.2e-20 70.9 0.9 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CCF50586.1 - 8.4e-17 60.5 0.1 1.5e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Dynactin PF12455.3 CCF50587.1 - 2e-74 249.9 1.3 2e-74 249.9 0.9 3.3 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 CCF50587.1 - 5.5e-22 77.2 0.7 9e-22 76.5 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain ATG16 PF08614.6 CCF50587.1 - 0.001 18.9 16.6 0.001 18.9 11.5 5.2 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) BAAT_C PF08840.6 CCF50587.1 - 0.7 9.5 4.7 3.1 7.4 0.1 3.2 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fcf1 PF04900.7 CCF50588.1 - 2e-25 88.8 0.2 2e-25 88.8 0.2 1.8 2 0 0 2 2 2 1 Fcf1 Plasmid_Txe PF06769.8 CCF50588.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Plasmid encoded toxin Txe DUF1675 PF07897.6 CCF50588.1 - 1.7 8.4 22.2 1.9 8.2 14.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) DUF1088 PF06469.6 CCF50588.1 - 8.7 5.7 9.3 0.89 8.9 1.4 2.4 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1088) TAFII55_N PF04658.8 CCF50589.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 TAFII55 protein conserved region SKG6 PF08693.5 CCF50589.1 - 0.084 12.1 0.3 0.16 11.3 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ctr PF04145.10 CCF50589.1 - 0.27 11.2 2.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Tocopherol_cycl PF14249.1 CCF50590.1 - 0.00035 19.3 0.1 0.00065 18.5 0.1 1.4 1 0 0 1 1 1 1 Tocopherol cyclase Cellulase PF00150.13 CCF50591.1 - 1.2e-10 41.0 0.0 0.00014 21.2 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Herpes_heli_pri PF05774.6 CCF50591.1 - 0.0078 16.2 0.9 0.0078 16.2 0.6 1.7 2 0 0 2 2 2 1 Herpesvirus helicase-primase complex component DUF974 PF06159.8 CCF50592.1 - 2e-65 220.6 0.0 3e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) IDO PF01231.13 CCF50593.1 - 8.4e-153 508.7 0.0 1.2e-152 508.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase ACPS PF01648.15 CCF50593.1 - 1.5e-11 44.0 0.0 1e-10 41.3 0.0 2.4 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily Ras PF00071.17 CCF50594.1 - 9e-66 220.2 1.1 1.1e-65 219.9 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF50594.1 - 6.3e-21 75.0 0.0 1.1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF50594.1 - 5.3e-18 64.8 0.2 7.1e-18 64.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF50594.1 - 1.4e-06 27.9 0.2 3.1e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF50594.1 - 1.5e-06 27.5 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF50594.1 - 2.4e-05 24.2 0.1 4.8e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCF50594.1 - 4.4e-05 22.7 0.1 5.5e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCF50594.1 - 0.00075 19.6 0.0 0.0018 18.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 CCF50594.1 - 0.0034 17.5 0.1 0.53 10.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCF50594.1 - 0.0035 16.5 0.4 0.053 12.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCF50594.1 - 0.0045 16.2 0.1 0.043 13.0 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 CCF50594.1 - 0.01 15.8 0.3 0.053 13.5 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CCF50594.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CCF50594.1 - 0.014 14.8 0.1 0.1 12.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCF50594.1 - 0.048 13.9 0.1 0.088 13.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 CCF50594.1 - 0.071 12.6 0.1 1.1 8.7 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCF50594.1 - 0.072 12.0 0.1 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin Nse4_C PF08743.5 CCF50595.1 - 3.4e-21 75.0 1.2 3.5e-20 71.8 0.1 2.7 2 1 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CCF50595.1 - 5.1e-13 48.6 0.3 5.1e-13 48.6 0.2 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE SRR1 PF07985.7 CCF50596.1 - 7.1e-14 51.4 0.0 7.4e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 SRR1 Neurochondrin PF05536.6 CCF50596.1 - 0.096 10.9 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin Erf4 PF10256.4 CCF50597.1 - 3.1e-32 110.9 0.0 3.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.14 CCF50598.1 - 3e-33 113.2 0.1 5.7e-33 112.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CCF50598.1 - 4e-32 110.4 1.5 8.3e-32 109.4 1.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CCF50598.1 - 0.00032 20.4 0.0 0.00058 19.6 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease S6PP_C PF08472.5 CCF50598.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal KH_1 PF00013.24 CCF50599.1 - 7.4e-31 105.5 1.0 2.2e-09 36.8 0.0 6.0 6 0 0 6 6 6 5 KH domain KH_3 PF13014.1 CCF50599.1 - 1.3e-22 78.9 3.1 2.9e-07 29.9 0.1 5.9 5 0 0 5 5 5 4 KH domain ArsA_ATPase PF02374.10 CCF50600.1 - 7.6e-112 373.2 0.4 8.8e-112 373.0 0.3 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCF50600.1 - 1.4e-14 53.9 0.1 2.1e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCF50600.1 - 7.2e-08 32.5 0.0 2.6e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CCF50600.1 - 3.5e-05 23.1 0.0 0.00011 21.5 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CCF50600.1 - 4.4e-05 23.0 0.4 0.00043 19.7 0.1 2.4 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 CCF50600.1 - 0.0023 17.3 0.0 0.0046 16.3 0.0 1.6 1 1 0 1 1 1 1 YhjQ protein PhoH PF02562.11 CCF50600.1 - 0.0084 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 CCF50600.1 - 0.0089 15.4 0.7 0.057 12.8 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCF50600.1 - 0.014 15.1 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain MipZ PF09140.6 CCF50600.1 - 0.027 13.5 0.1 0.066 12.2 0.1 1.6 1 1 1 2 2 2 0 ATPase MipZ NB-ARC PF00931.17 CCF50600.1 - 0.043 12.6 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 CCF50600.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CCF50600.1 - 0.099 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein BPL_N PF09825.4 CCF50601.1 - 2.6e-82 276.5 0.0 6.3e-81 271.9 0.0 2.3 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CCF50601.1 - 8.4e-13 48.4 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family RTC PF01137.16 CCF50602.1 - 1.2e-57 194.3 0.0 1.6e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCF50602.1 - 1.1e-29 102.4 0.0 1.9e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PBP1_TM PF14812.1 CCF50602.1 - 0.15 12.3 2.0 0.3 11.4 1.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phytochelatin_C PF09328.5 CCF50602.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Ribonuc_2-5A PF06479.7 CCF50603.1 - 7.6e-46 155.1 0.1 1.4e-45 154.3 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 CCF50603.1 - 3e-41 141.2 0.0 4.9e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50603.1 - 2.2e-19 69.5 0.0 5.3e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 CCF50603.1 - 2.8e-06 26.9 0.7 7.3e-05 22.3 0.1 3.1 2 1 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 CCF50603.1 - 0.0011 18.4 0.0 0.053 13.0 0.0 2.9 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 CCF50603.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gE PF02480.11 CCF50603.1 - 0.036 12.3 0.1 0.081 11.1 0.1 1.6 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E YrbL-PhoP_reg PF10707.4 CCF50603.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4006 PF13179.1 CCF50603.1 - 0.091 12.3 0.3 0.24 10.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) PBP1_TM PF14812.1 CCF50603.1 - 1.5 9.2 24.1 15 5.9 0.0 3.7 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_12 PF13424.1 CCF50604.1 - 1.7e-08 34.2 4.8 0.36 10.7 0.0 7.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF50604.1 - 4.4e-08 33.3 2.2 0.37 11.1 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF50604.1 - 1e-06 28.7 21.1 40 5.2 0.0 12.0 9 4 4 13 13 13 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCF50604.1 - 4.2e-06 27.2 11.8 0.33 11.7 0.0 6.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50604.1 - 0.0014 18.3 16.3 11 6.1 0.2 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCF50604.1 - 0.03 14.0 8.9 0.18 11.5 0.2 5.8 7 1 1 8 8 8 0 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 CCF50604.1 - 0.032 13.9 6.4 5.5 7.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF50604.1 - 0.065 13.0 9.2 41 4.3 0.0 7.6 8 1 1 9 9 9 0 Tetratricopeptide repeat PPR_3 PF13812.1 CCF50604.1 - 0.073 13.3 0.1 2.8 8.4 0.0 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_17 PF13431.1 CCF50604.1 - 1.8 8.9 9.8 1.5e+02 2.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Zn_clus PF00172.13 CCF50605.1 - 3.7e-06 26.7 6.5 3.7e-06 26.7 4.5 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.13 CCF50606.1 - 9.1e-55 185.2 0.1 1.6e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Brix domain CybS PF05328.7 CCF50607.1 - 1.8e-43 147.3 0.0 2.2e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 CybS Ribosomal_L3 PF00297.17 CCF50608.1 - 3e-120 400.5 8.7 3.6e-120 400.2 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Oxidored_molyb PF00174.14 CCF50609.1 - 1.3e-52 177.5 0.0 2.1e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CCF50609.1 - 1.9e-44 150.5 0.0 3.1e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 CCF50609.1 - 3.3e-27 95.1 0.0 8e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCF50609.1 - 1e-22 80.0 0.0 6.2e-22 77.5 0.0 2.3 3 0 0 3 3 3 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 CCF50609.1 - 1.3e-21 76.1 0.1 2.9e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 CCF50609.1 - 0.0081 16.0 0.0 0.069 13.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 CCF50610.1 - 8.3e-30 103.2 0.1 1.4e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 CCF50610.1 - 7.2e-24 84.7 0.0 8.8e-23 81.2 0.0 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 CCF50610.1 - 2.1e-13 50.0 5.7 5.2e-12 45.6 1.8 3.0 3 0 0 3 3 2 1 BFD-like [2Fe-2S] binding domain Pyr_redox PF00070.22 CCF50610.1 - 2.5e-13 50.2 2.6 5.6e-13 49.1 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 CCF50610.1 - 1.6e-12 47.0 0.0 4.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 CCF50610.1 - 5.2e-10 38.7 0.0 1.2e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 CCF50610.1 - 6.4e-10 38.4 0.2 2.1e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.1 CCF50610.1 - 3.6e-06 26.8 1.5 0.066 12.9 0.0 3.7 2 2 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCF50610.1 - 2.3e-05 24.5 1.7 0.0037 17.3 0.1 3.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF50610.1 - 6e-05 22.0 0.5 0.00072 18.5 0.0 2.6 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 CCF50610.1 - 0.0033 16.3 0.7 7.7 5.2 0.1 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase TrkA_N PF02254.13 CCF50610.1 - 0.026 14.4 1.3 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain adh_short PF00106.20 CCF50610.1 - 0.088 12.7 0.1 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 CCF50611.1 - 9e-32 110.1 27.0 9e-32 110.1 18.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Glu_synthase PF01645.12 CCF50612.1 - 4.2e-160 532.6 0.1 8.2e-160 531.6 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCF50612.1 - 4.3e-136 453.3 0.0 5.7e-136 452.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCF50612.1 - 2e-119 398.1 0.0 8.2e-119 396.1 0.0 1.9 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 CCF50612.1 - 6.3e-64 214.6 0.2 1e-63 214.0 0.1 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCF50612.1 - 1.7e-22 79.1 0.1 3.5e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCF50612.1 - 2.1e-14 53.9 0.0 8.3e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF50612.1 - 7e-10 39.2 0.1 0.0003 20.9 0.1 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF50612.1 - 7.4e-09 35.5 0.9 1.9e-08 34.2 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCF50612.1 - 1.5e-08 34.9 0.2 9.8e-05 22.6 0.0 3.3 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCF50612.1 - 4.7e-06 25.9 0.1 7.4e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CCF50612.1 - 7.3e-06 25.1 3.1 3.3e-05 22.9 0.2 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF50612.1 - 1.4e-05 23.7 1.6 0.00011 20.7 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 CCF50612.1 - 1.6e-05 23.9 0.8 0.065 12.0 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCF50612.1 - 0.00015 20.7 3.7 0.0029 16.5 0.2 2.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 CCF50612.1 - 0.00058 20.0 0.1 0.7 10.1 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 CCF50612.1 - 0.00062 18.9 5.1 0.013 14.5 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CCF50612.1 - 0.00069 19.2 0.1 0.36 10.3 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 CCF50612.1 - 0.0061 15.6 0.4 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCF50612.1 - 0.0061 15.6 1.2 0.026 13.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FMN_dh PF01070.13 CCF50612.1 - 0.007 15.2 0.8 0.065 12.0 0.5 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FMO-like PF00743.14 CCF50612.1 - 0.024 12.8 0.1 0.55 8.3 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.16 CCF50612.1 - 0.024 14.4 0.5 15 5.4 0.0 3.3 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.1 CCF50612.1 - 0.049 13.5 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Shikimate_DH PF01488.15 CCF50612.1 - 0.05 13.6 0.2 18 5.4 0.1 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CCF50612.1 - 0.061 12.6 1.1 0.37 10.1 0.1 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 CCF50612.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DJ-1_PfpI PF01965.19 CCF50612.1 - 0.076 12.4 0.1 0.35 10.3 0.0 2.1 2 1 1 3 3 3 0 DJ-1/PfpI family Lycopene_cycl PF05834.7 CCF50612.1 - 0.086 11.7 0.4 4.9 5.9 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCF50612.1 - 0.28 10.8 0.2 0.77 9.3 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Adenylsucc_synt PF00709.16 CCF50613.1 - 1.6e-163 544.2 0.0 1.8e-163 544.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DNA_primase_lrg PF04104.9 CCF50614.1 - 4.6e-82 275.2 0.0 7.2e-82 274.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Nucleoporin_C PF03177.9 CCF50615.1 - 3.7e-97 326.2 9.5 4.5e-97 325.9 6.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCF50615.1 - 1e-35 123.3 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like E1_dh PF00676.15 CCF50616.1 - 2.8e-111 371.0 0.5 3.2e-111 370.8 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCF50616.1 - 0.00046 19.2 0.2 0.00075 18.5 0.2 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CCF50616.1 - 0.0017 17.9 6.3 0.0029 17.2 2.4 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 CCF50616.1 - 0.074 11.8 0.4 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain NADH_B2 PF14813.1 CCF50617.1 - 0.00033 20.2 1.2 0.00042 19.9 0.8 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SWIRM PF04433.12 CCF50618.1 - 1e-34 118.5 0.1 3.1e-34 116.9 0.1 1.9 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 CCF50618.1 - 3.3e-10 39.3 3.4 5.9e-10 38.5 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 CCF50618.1 - 2.7e-07 30.5 0.5 4.9e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCF50618.1 - 3e-07 30.3 0.0 7.6e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PhoD PF09423.5 CCF50619.1 - 1.2e-39 136.1 1.2 2.2e-39 135.2 0.2 1.9 3 0 0 3 3 3 1 PhoD-like phosphatase TEBP_beta PF07404.6 CCF50619.1 - 2.8 6.9 7.6 24 3.9 0.0 2.4 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) His_biosynth PF00977.16 CCF50620.1 - 4.1e-40 137.4 0.0 6.2e-24 84.5 0.0 2.7 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 CCF50620.1 - 9.3e-23 80.6 0.0 1.5e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCF50620.1 - 1.4e-07 31.2 0.1 5.9e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CCF50620.1 - 3.3e-07 30.1 0.0 1.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CCF50620.1 - 0.064 12.6 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Asp PF00026.18 CCF50622.1 - 2.6e-48 164.8 0.0 3.6e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF50622.1 - 2.1e-11 44.0 0.6 1.4e-10 41.3 0.4 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCF50622.1 - 3.5e-06 27.4 0.0 0.14 12.6 0.0 3.8 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 CCF50622.1 - 3.7e-05 23.3 0.0 8.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 CCF50622.1 - 0.14 12.0 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease ABC_membrane PF00664.18 CCF50623.1 - 3.5e-47 161.1 14.4 4.1e-23 82.1 3.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CCF50623.1 - 4.5e-44 150.0 0.0 5.6e-25 88.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF50623.1 - 1.2e-09 37.7 0.0 0.0001 21.6 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF50623.1 - 1.4e-07 31.8 0.1 2.5 8.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 CCF50623.1 - 3.8e-06 26.4 0.3 0.01 15.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF50623.1 - 7.4e-06 25.4 0.1 0.069 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF50623.1 - 2.9e-05 24.2 0.4 1.9 8.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCF50623.1 - 0.00013 22.0 2.4 0.33 10.9 0.1 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 CCF50623.1 - 0.00021 21.7 0.1 0.95 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCF50623.1 - 0.00025 20.6 0.0 0.65 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain T2SE PF00437.15 CCF50623.1 - 0.00047 19.1 0.0 0.15 10.9 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein SbcCD_C PF13558.1 CCF50623.1 - 0.0017 18.2 0.3 1.5 8.8 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CCF50623.1 - 0.0043 16.7 0.3 2.8 7.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CCF50623.1 - 0.005 16.5 0.1 0.35 10.6 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 CCF50623.1 - 0.0051 16.4 0.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCF50623.1 - 0.0054 17.5 3.9 2.6 8.8 1.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 CCF50623.1 - 0.0071 16.0 1.0 0.51 9.9 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 CCF50623.1 - 0.013 15.9 0.1 6.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 CCF50623.1 - 0.015 14.7 2.6 0.063 12.7 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CCF50623.1 - 0.027 14.4 0.1 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CCF50623.1 - 0.035 13.9 0.2 4.2 7.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCF50623.1 - 0.055 12.9 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 CCF50623.1 - 0.06 12.5 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 CCF50623.1 - 0.084 12.6 0.2 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CCF50623.1 - 0.15 11.7 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 CCF50623.1 - 0.18 11.6 0.7 17 5.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 CCF50623.1 - 0.21 10.4 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.12 CCF50623.1 - 0.22 11.0 3.0 2.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 CCF50623.1 - 0.38 10.0 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 CCF50623.1 - 0.45 10.8 5.4 11 6.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CCF50623.1 - 0.46 9.0 3.0 2.3 6.7 0.1 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.10 CCF50623.1 - 0.8 9.3 3.6 15 5.2 0.0 2.8 3 0 0 3 3 2 0 NTPase VHS PF00790.14 CCF50624.1 - 1.9e-37 128.0 3.4 6.5e-37 126.3 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 CCF50624.1 - 3.6e-17 62.0 10.5 8.1e-17 60.8 7.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 CCF50624.1 - 0.00015 21.0 6.5 0.045 13.3 0.6 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 CCF50624.1 - 0.002 18.0 3.4 0.002 18.0 2.3 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger RNA_pol_Rpb1_1 PF04997.7 CCF50625.1 - 1.4e-111 373.0 0.0 1.9e-111 372.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CCF50625.1 - 2.6e-103 345.0 0.2 3.8e-103 344.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCF50625.1 - 2.2e-66 222.9 0.0 4.2e-66 221.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCF50625.1 - 7.9e-62 208.3 0.1 1.5e-61 207.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 CCF50625.1 - 2.4e-46 156.8 1.2 2.4e-46 156.8 0.8 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 CCF50625.1 - 1.1e-45 155.1 0.0 2.1e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCF50625.1 - 1e-35 121.7 0.0 2.4e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CCF50625.1 - 2.2e-16 58.4 186.3 0.012 15.6 6.5 13.6 9 2 7 16 16 16 15 RNA polymerase Rpb1 C-terminal repeat NmrA PF05368.8 CCF50626.1 - 2.9e-05 23.4 0.0 3.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RhoGAP PF00620.22 CCF50627.1 - 2.3e-47 160.3 1.8 3e-46 156.7 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCF50627.1 - 1.3e-13 50.7 19.0 2.5e-08 33.8 2.2 3.5 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 CCF50627.1 - 2.5e-07 30.3 7.4 2.5e-07 30.3 5.2 3.9 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Rotamase_2 PF13145.1 CCF50627.1 - 0.37 11.4 5.8 0.46 11.1 0.7 3.1 3 0 0 3 3 3 0 PPIC-type PPIASE domain Ras PF00071.17 CCF50628.1 - 3.8e-66 221.4 0.0 4.6e-66 221.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF50628.1 - 2.9e-19 69.7 0.0 4.3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF50628.1 - 4.9e-14 51.9 0.0 6.1e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF50628.1 - 7.8e-07 28.4 0.0 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF50628.1 - 7.3e-06 25.5 0.1 1.9e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF50628.1 - 3e-05 23.9 0.0 9.5e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF50628.1 - 0.00062 19.0 0.0 0.0075 15.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CCF50628.1 - 0.00079 18.6 0.0 0.001 18.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCF50628.1 - 0.023 14.6 0.3 0.052 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCF50628.1 - 0.036 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF50628.1 - 0.043 13.9 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CCF50628.1 - 0.044 13.9 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCF50628.1 - 0.052 12.7 0.0 0.079 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CCF50628.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Tox-PLDMTX PF15645.1 CCF50628.1 - 0.087 12.8 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Septin PF00735.13 CCF50628.1 - 0.091 11.7 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 CCF50628.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MCM PF00493.18 CCF50628.1 - 0.12 11.1 0.0 0.36 9.5 0.0 1.7 2 1 1 3 3 3 0 MCM2/3/5 family U3_assoc_6 PF08640.6 CCF50629.1 - 2.4e-23 81.6 0.3 1.2e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_11 PF13414.1 CCF50629.1 - 0.1 12.2 1.3 0.35 10.5 0.9 2.0 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 CCF50629.1 - 0.19 12.4 3.5 6.8 7.6 0.2 4.8 2 1 2 4 4 4 0 Tetratricopeptide repeat ATP11 PF06644.6 CCF50630.1 - 8.6e-79 264.7 0.6 1.1e-78 264.4 0.4 1.1 1 0 0 1 1 1 1 ATP11 protein Nefa_Nip30_N PF10187.4 CCF50630.1 - 0.27 11.4 5.6 0.067 13.3 1.0 2.1 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Maf_N PF08383.6 CCF50631.1 - 0.096 12.2 0.3 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Maf N-terminal region MFS_1 PF07690.11 CCF50632.1 - 8.9e-22 77.2 43.8 1.4e-15 56.8 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1449 PF07290.6 CCF50632.1 - 0.13 11.5 4.5 0.059 12.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) HA2 PF04408.18 CCF50633.1 - 6.4e-17 61.4 0.1 1.8e-16 59.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF50633.1 - 2.9e-13 49.4 0.0 5.8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF50633.1 - 1.9e-10 40.4 0.0 3.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CCF50633.1 - 7.5e-09 35.4 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CCF50633.1 - 8.9e-05 22.6 0.0 0.0003 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCF50633.1 - 0.0035 16.4 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SE PF00437.15 CCF50633.1 - 0.018 13.9 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 CCF50633.1 - 0.019 14.7 0.3 0.32 10.7 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain Peptidase_MA_2 PF13485.1 CCF50633.1 - 0.08 12.9 0.2 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase MA superfamily DUF494 PF04361.8 CCF50633.1 - 0.085 12.5 0.2 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF494) ABC_tran PF00005.22 CCF50633.1 - 0.11 12.7 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ResIII PF04851.10 CCF50633.1 - 0.17 11.6 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CCF50633.1 - 0.33 11.2 0.0 0.73 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.16 CCF50634.1 - 9.3e-230 764.3 5.2 1.5e-229 763.5 3.6 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCF50634.1 - 3.3e-41 140.8 0.0 6.3e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 CCF50634.1 - 9.7e-12 44.0 0.5 3e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCF50634.1 - 2e-09 36.9 0.1 4.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF50634.1 - 1.2e-08 34.2 0.0 1.6e-07 30.7 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 CCF50634.1 - 0.0026 17.8 0.0 0.01 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF50634.1 - 0.0089 15.1 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 CCF50634.1 - 0.037 14.8 0.0 0.18 12.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CCF50634.1 - 0.074 12.3 0.4 5 6.4 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 CCF50634.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain IQ PF00612.22 CCF50634.1 - 1.4 8.7 6.9 5.7 6.8 0.3 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif HMGL-like PF00682.14 CCF50635.1 - 4.5e-72 242.5 0.5 6.8e-72 241.9 0.4 1.3 1 0 0 1 1 1 1 HMGL-like OTU PF02338.14 CCF50636.1 - 8.6e-21 74.7 0.1 2.3e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Mak16 PF04874.9 CCF50636.1 - 0.0091 16.0 1.8 0.017 15.2 1.3 1.4 1 0 0 1 1 1 1 Mak16 protein C-terminal region Peptidase_C65 PF10275.4 CCF50636.1 - 0.096 12.0 0.0 9.3 5.5 0.0 2.3 1 1 0 2 2 2 0 Peptidase C65 Otubain Colicin-DNase PF12639.2 CCF50636.1 - 0.12 12.5 0.4 3.9 7.7 0.0 2.2 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin PAP2 PF01569.16 CCF50639.1 - 1.1e-13 51.0 3.6 1.1e-13 51.0 2.5 1.8 2 0 0 2 2 2 1 PAP2 superfamily dCMP_cyt_deam_1 PF00383.17 CCF50639.1 - 2.4e-11 43.2 0.2 7.7e-11 41.5 0.2 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CCF50639.1 - 0.015 14.9 0.3 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF212 PF02681.9 CCF50639.1 - 0.088 12.5 0.1 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Divergent PAP2 family Polysacc_synt_C PF14667.1 CCF50639.1 - 0.12 12.1 3.4 0.24 11.1 2.4 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain EamA PF00892.15 CCF50640.1 - 7.6e-22 77.6 30.4 6.8e-14 52.0 4.4 2.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCF50640.1 - 0.00016 21.8 28.4 0.00032 20.8 4.4 3.7 3 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF4637 PF15470.1 CCF50640.1 - 3.5 7.2 6.7 8.8 5.9 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) GP120 PF00516.13 CCF50641.1 - 0.064 11.4 0.1 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Bac_rhodopsin PF01036.13 CCF50642.1 - 5.5e-40 137.0 17.9 7.8e-40 136.5 12.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.13 CCF50642.1 - 0.17 11.4 10.9 0.019 14.5 4.0 2.0 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein HEM4 PF02602.10 CCF50643.1 - 7.9e-17 61.2 0.1 1.2e-09 37.7 0.0 3.0 2 1 0 2 2 2 2 Uroporphyrinogen-III synthase HemD 3Beta_HSD PF01073.14 CCF50644.1 - 1.5e-58 197.7 0.0 9.4e-53 178.7 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCF50644.1 - 4.1e-26 91.8 0.0 6.2e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCF50644.1 - 1.9e-10 40.1 0.2 1.6e-09 37.0 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 CCF50644.1 - 4.5e-09 36.5 0.0 2.8e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCF50644.1 - 7.4e-08 31.6 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCF50644.1 - 4.3e-05 22.5 0.1 0.00029 19.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCF50644.1 - 0.0013 18.6 0.1 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 CCF50644.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CCF50644.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aminotran_5 PF00266.14 CCF50645.1 - 1.5e-19 70.0 0.0 2.2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCF50645.1 - 4.3e-06 25.9 0.0 7.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II APG17 PF04108.7 CCF50645.1 - 0.11 11.2 0.5 0.19 10.5 0.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Complex1_LYR_2 PF13233.1 CCF50645.1 - 0.58 10.6 2.2 33 5.0 0.0 2.6 2 1 0 2 2 2 0 Complex1_LYR-like SNF2_N PF00176.18 CCF50646.1 - 1e-69 234.6 0.3 1.7e-68 230.6 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF50646.1 - 3.4e-17 62.0 0.0 1.1e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCF50646.1 - 2.3e-10 39.7 2.4 3.6e-08 32.5 0.0 3.2 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 AT_hook PF02178.14 CCF50646.1 - 0.073 12.7 5.0 0.26 11.0 3.5 2.1 1 0 0 1 1 1 0 AT hook motif DUF3040 PF11239.3 CCF50647.1 - 5.9 7.0 5.9 1.9 8.6 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SNF2_N PF00176.18 CCF50648.1 - 1.7e-26 92.6 0.0 5.6e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 CCF50648.1 - 8.5e-13 48.1 0.8 1.2e-11 44.3 0.0 2.7 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Activator-TraM PF11657.3 CCF50648.1 - 5.1 6.5 13.3 3.4 7.1 0.0 3.2 3 0 0 3 3 3 0 Transcriptional activator TraM SHQ1 PF04925.10 CCF50649.1 - 6.6e-33 113.7 0.0 9.5e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein HSBP1 PF06825.7 CCF50649.1 - 0.087 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 WAPL PF07814.8 CCF50650.1 - 3.7e-09 35.7 4.3 5.7e-09 35.1 0.0 2.9 3 0 0 3 3 3 1 Wings apart-like protein regulation of heterochromatin BIR PF00653.16 CCF50651.1 - 8e-27 93.4 0.6 3e-21 75.6 0.6 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.10 CCF50651.1 - 0.024 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger Pkinase PF00069.20 CCF50652.1 - 2.4e-64 216.9 0.0 3.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50652.1 - 2.4e-27 95.6 0.0 3.4e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF50652.1 - 0.00073 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pro_isomerase PF00160.16 CCF50654.1 - 1e-44 152.4 0.1 1.2e-44 152.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transaldolase PF00923.14 CCF50655.1 - 4.9e-97 324.5 1.6 5.6e-97 324.3 1.1 1.0 1 0 0 1 1 1 1 Transaldolase UreD PF01774.12 CCF50656.1 - 3e-59 200.0 0.0 4.5e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 UreD urease accessory protein EI24 PF07264.6 CCF50656.1 - 0.11 11.9 14.4 0.64 9.4 10.0 2.1 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) CorA PF01544.13 CCF50657.1 - 1.2e-07 31.0 4.9 1.1e-06 27.8 3.4 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein APG17 PF04108.7 CCF50657.1 - 0.23 10.2 1.6 0.27 9.9 0.3 1.6 2 0 0 2 2 2 0 Autophagy protein Apg17 IncA PF04156.9 CCF50657.1 - 6.4 6.3 6.2 1.8e+02 1.5 3.0 3.0 2 1 0 2 2 2 0 IncA protein FH2 PF02181.18 CCF50658.1 - 6.3e-64 216.1 6.1 6.3e-64 216.1 4.2 2.4 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CCF50658.1 - 4.2e-45 153.4 0.6 2.1e-44 151.1 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CCF50658.1 - 6.4e-44 149.7 0.9 2.7e-43 147.6 0.0 2.4 2 1 1 3 3 3 1 Diaphanous FH3 Domain HECT_2 PF09814.4 CCF50661.1 - 4.1e-25 88.2 0.0 4.9e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding hNIFK_binding PF12196.3 CCF50662.1 - 0.051 12.9 0.1 0.16 11.4 0.1 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK DUF2383 PF09537.5 CCF50662.1 - 2.6 8.3 8.7 0.56 10.4 2.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Folate_carrier PF01770.13 CCF50662.1 - 7.9 4.8 6.8 13 4.1 4.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier EXS PF03124.9 CCF50663.1 - 4.6e-81 272.5 21.9 6.6e-81 272.0 15.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCF50663.1 - 1.4e-45 156.2 0.2 1.4e-45 156.2 0.2 2.4 2 0 0 2 2 2 1 SPX domain Prothymosin PF03247.9 CCF50663.1 - 0.2 11.8 29.8 0.6 10.2 20.7 1.8 1 0 0 1 1 1 0 Prothymosin/parathymosin family Herpes_BLLF1 PF05109.8 CCF50663.1 - 1.8 6.4 8.8 2.7 5.8 6.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) NOA36 PF06524.7 CCF50663.1 - 3.6 6.7 15.3 6.7 5.8 10.6 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 CCF50663.1 - 4 6.9 22.1 9.8 5.6 15.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 CCF50663.1 - 4.5 5.0 26.6 0.17 9.7 13.4 2.0 2 0 0 2 2 2 0 Nop14-like family Paf1 PF03985.8 CCF50663.1 - 5.5 5.6 26.4 14 4.3 0.2 2.4 2 0 0 2 2 2 0 Paf1 Vps51 PF08700.6 CCF50664.1 - 1.6e-17 63.0 1.9 3e-17 62.2 0.3 2.3 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 CCF50664.1 - 0.00043 20.1 0.3 0.0018 18.1 0.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S15 PF00312.17 CCF50665.1 - 5.1e-18 64.6 1.0 9.5e-18 63.7 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 PPK2 PF03976.9 CCF50665.1 - 0.034 13.4 0.1 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) RRM_1 PF00076.17 CCF50666.1 - 1.2e-13 50.4 0.0 2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50666.1 - 1.2e-11 44.3 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50666.1 - 9e-10 38.2 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) rve PF00665.21 CCF50667.1 - 1.9e-13 50.5 0.1 4.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF50667.1 - 1.6e-06 27.6 0.4 4.1e-06 26.3 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3391 PF11871.3 CCF50667.1 - 0.065 13.4 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Flavi_glycop_C PF02832.11 CCF50667.1 - 0.11 12.4 0.2 0.82 9.6 0.1 2.4 1 1 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain Dopey_N PF04118.9 CCF50668.1 - 8.6e-110 366.3 0.0 2e-109 365.1 0.0 1.6 1 0 0 1 1 1 1 Dopey, N-terminal AFT PF08731.6 CCF50669.1 - 0.15 12.2 0.3 0.14 12.3 0.2 1.2 1 1 0 1 1 1 0 Transcription factor AFT Med15 PF09606.5 CCF50670.1 - 0.0095 14.2 60.0 0.01 14.0 41.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CCF50670.1 - 1.2 6.7 18.7 1.3 6.6 13.0 1.1 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 CCF50670.1 - 2.2 7.6 25.9 3.2 7.0 18.0 1.4 1 0 0 1 1 1 0 DDRGK domain Rib_5-P_isom_A PF06026.9 CCF50673.1 - 1e-54 184.4 0.0 1.4e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCF50673.1 - 0.0059 16.2 0.0 0.41 10.2 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain NUC173 PF08161.7 CCF50674.1 - 2.3e-51 173.9 0.0 8.7e-50 168.8 0.0 2.8 2 1 0 2 2 2 1 NUC173 domain Cnd1 PF12717.2 CCF50674.1 - 0.019 14.8 0.6 0.46 10.2 0.0 2.7 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 YqzH PF14164.1 CCF50674.1 - 0.19 11.6 0.1 0.58 10.1 0.0 1.8 1 0 0 1 1 1 0 YqzH-like protein SET PF00856.23 CCF50675.1 - 3.7e-11 43.5 0.0 1.3e-10 41.7 0.0 2.0 1 1 0 1 1 1 1 SET domain HMGL-like PF00682.14 CCF50676.1 - 5.5e-63 212.7 0.0 8.1e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CCF50676.1 - 6.7e-20 71.2 1.8 1e-08 35.0 0.0 3.0 3 1 0 3 3 3 2 LeuA allosteric (dimerisation) domain DUF1227 PF06777.6 CCF50677.1 - 2.4e-59 199.2 0.1 4.2e-59 198.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CCF50677.1 - 2.7e-47 160.3 0.1 6.3e-42 142.9 0.0 2.3 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 CCF50677.1 - 2.3e-45 154.5 0.0 5.9e-45 153.2 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 CCF50677.1 - 0.0018 17.7 0.3 0.32 10.4 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 CCF50677.1 - 0.0023 17.8 0.1 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCF50677.1 - 0.0045 15.8 0.0 0.6 8.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 CCF50677.1 - 0.012 15.7 0.2 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CCF50677.1 - 0.024 13.6 0.1 1.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CCF50677.1 - 0.052 12.7 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein YtxC PF08812.6 CCF50677.1 - 0.058 12.8 0.4 0.29 10.6 0.0 2.3 2 0 0 2 2 2 0 YtxC-like family AAA_11 PF13086.1 CCF50677.1 - 0.1 12.1 0.2 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain rve PF00665.21 CCF50678.1 - 9.1e-12 45.1 0.1 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF50678.1 - 0.0032 16.4 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF50679.1 - 7e-20 71.0 0.1 8.6e-15 54.3 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran PF00005.22 CCF50680.1 - 4.3e-45 153.3 0.9 7.8e-22 78.0 0.0 5.0 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CCF50680.1 - 1.9e-18 67.4 2.8 0.00015 21.8 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 CCF50680.1 - 1e-13 51.0 1.4 0.017 14.3 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF50680.1 - 8.3e-10 38.0 0.4 0.0015 18.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 CCF50680.1 - 4.7e-08 32.8 0.1 0.076 12.4 0.0 4.5 4 1 0 5 5 5 2 AAA-like domain AAA_22 PF13401.1 CCF50680.1 - 7.7e-07 29.3 0.0 0.13 12.4 0.0 4.6 5 0 0 5 5 5 2 AAA domain CLASP_N PF12348.3 CCF50680.1 - 1.5e-06 27.7 0.1 1e-05 25.0 0.0 2.4 2 1 0 2 2 1 1 CLASP N terminal HEAT_2 PF13646.1 CCF50680.1 - 2.5e-06 27.6 0.1 0.026 14.7 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats AAA_17 PF13207.1 CCF50680.1 - 3.5e-06 27.8 0.0 0.031 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CCF50680.1 - 4.4e-06 26.5 0.0 0.0051 16.7 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Chromo PF00385.19 CCF50680.1 - 4.6e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 CCF50680.1 - 7.2e-06 26.4 5.6 0.046 14.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain Miro PF08477.8 CCF50680.1 - 8.8e-06 26.2 0.0 0.049 14.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CCF50680.1 - 2.4e-05 24.2 0.1 0.059 13.3 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CCF50680.1 - 3.5e-05 23.0 0.0 1.8 7.5 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.7 CCF50680.1 - 7e-05 22.5 0.0 0.57 9.8 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA PF00004.24 CCF50680.1 - 0.00027 21.1 0.0 2.6 8.2 0.0 4.9 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCF50680.1 - 0.00029 20.5 2.8 2.3 7.9 0.0 5.1 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) MobB PF03205.9 CCF50680.1 - 0.00029 20.5 0.2 0.72 9.5 0.1 3.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CCF50680.1 - 0.00034 20.5 3.9 0.19 11.4 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_33 PF13671.1 CCF50680.1 - 0.0005 19.9 0.0 0.95 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCF50680.1 - 0.00054 19.5 0.2 1.1 8.7 0.0 2.9 3 0 0 3 3 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 CCF50680.1 - 0.00055 19.1 0.0 0.42 9.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 CCF50680.1 - 0.0007 19.5 0.0 1.8 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain HEAT PF02985.17 CCF50680.1 - 0.001 18.9 1.4 0.31 11.2 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat AAA_18 PF13238.1 CCF50680.1 - 0.0013 19.0 0.1 0.37 11.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCF50680.1 - 0.0014 17.4 0.5 0.31 9.7 0.0 2.7 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 CCF50680.1 - 0.0019 18.2 6.5 0.027 14.4 0.1 4.2 4 1 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.17 CCF50680.1 - 0.0021 18.1 0.0 4.4 7.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 CCF50680.1 - 0.0023 17.6 0.8 4 7.0 0.2 3.8 3 1 0 3 3 3 0 Archaeal ATPase AAA_13 PF13166.1 CCF50680.1 - 0.0024 16.4 0.0 0.85 8.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 CCF50680.1 - 0.0031 16.4 0.3 1.7 7.4 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain DUF3584 PF12128.3 CCF50680.1 - 0.0032 14.9 1.0 0.41 7.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) AAA_25 PF13481.1 CCF50680.1 - 0.004 16.5 0.0 6.1 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain HEAT_EZ PF13513.1 CCF50680.1 - 0.007 16.8 0.1 13 6.4 0.0 4.8 4 1 1 5 5 4 0 HEAT-like repeat DUF815 PF05673.8 CCF50680.1 - 0.022 13.6 0.3 4 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.15 CCF50680.1 - 0.024 13.3 0.0 6.1 5.4 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.14 CCF50680.1 - 0.033 13.6 0.2 10 5.4 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCF50680.1 - 0.036 13.7 0.0 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 CCF50680.1 - 0.036 13.9 0.0 4.9 7.0 0.0 3.5 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 CCF50680.1 - 0.13 11.7 0.6 7.8 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UME PF08064.8 CCF50680.1 - 0.22 11.5 0.8 2.6 8.0 0.2 2.5 1 1 1 2 2 2 0 UME (NUC010) domain Alkyl_sulf_dimr PF14863.1 CCF50680.1 - 0.23 11.6 1.6 2.6 8.2 0.2 2.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation EHN PF06441.7 CCF50681.1 - 9.8e-28 96.3 0.0 2.3e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CCF50681.1 - 4.6e-09 36.4 8.0 1.3e-08 35.0 3.7 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF50681.1 - 3e-07 30.2 1.2 8.3e-07 28.7 0.3 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Sec10 PF07393.6 CCF50684.1 - 1.4e-77 261.5 1.7 3.7e-76 256.8 0.0 3.0 3 1 0 3 3 3 1 Exocyst complex component Sec10 F-box PF00646.28 CCF50684.1 - 0.0012 18.4 0.1 0.003 17.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCF50684.1 - 0.0018 17.9 0.3 0.0048 16.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like Spo7 PF03907.8 CCF50685.1 - 1.8e-18 66.9 3.1 3.3e-18 66.0 2.1 1.3 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.4 CCF50685.1 - 0.015 15.2 0.3 0.015 15.2 0.2 1.7 2 0 0 2 2 2 0 Transmembrane protein 188 DUF2417 PF10329.4 CCF50685.1 - 0.042 13.2 0.1 0.062 12.6 0.1 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF2207 PF09972.4 CCF50685.1 - 0.09 11.3 0.4 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RhoGEF PF00621.15 CCF50686.1 - 6.3e-25 88.0 0.0 9.8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Mito_carr PF00153.22 CCF50689.1 - 3.3e-61 203.0 2.3 1.8e-24 85.2 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4604 PF15377.1 CCF50690.1 - 1.8e-20 73.7 23.9 5e-20 72.3 16.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) MRFAP1 PF15155.1 CCF50690.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.4 3 0 0 3 3 3 0 MORF4 family-associated protein1 DUF4557 PF15101.1 CCF50690.1 - 1.4 8.6 6.9 0.14 11.9 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF1365 PF07103.6 CCF50691.1 - 4.3e-26 91.5 0.2 5.4e-24 84.6 0.1 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Rep_fac-A_3 PF08661.6 CCF50692.1 - 2.6e-31 107.7 0.0 2.9e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA_anti-codon PF01336.20 CCF50692.1 - 0.074 12.9 0.4 0.13 12.1 0.3 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain She9_MDM33 PF05546.6 CCF50693.1 - 3.8e-68 229.1 12.4 6e-68 228.4 8.6 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family CytochromB561_N PF09786.4 CCF50693.1 - 7.2 4.9 18.2 7.6 4.8 11.7 1.5 1 1 1 2 2 2 0 Cytochrome B561, N terminal ATP-synt_D PF01813.12 CCF50694.1 - 4.8e-67 225.3 2.3 6.7e-67 224.8 1.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D MT PF12777.2 CCF50694.1 - 0.0063 15.3 0.1 0.0063 15.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DUF1510 PF07423.6 CCF50694.1 - 0.008 15.5 11.6 0.011 15.0 8.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CCF50694.1 - 0.39 9.8 6.8 0.8 8.8 4.7 1.6 1 0 0 1 1 1 0 Putative metallopeptidase domain HGTP_anticodon2 PF12745.2 CCF50694.1 - 0.62 9.1 11.1 1 8.4 7.7 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Hid1 PF12722.2 CCF50694.1 - 2.4 5.7 6.7 3 5.3 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 CCF50695.1 - 1.3e-16 59.7 10.3 0.0017 18.1 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat LETM1 PF07766.8 CCF50696.1 - 8.1e-97 323.4 2.0 8.1e-97 323.4 1.4 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 CCF50696.1 - 4.5e-07 29.8 0.2 3.5e-06 27.0 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CCF50696.1 - 5.5e-05 22.6 0.1 0.00015 21.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CCF50696.1 - 0.00074 18.6 0.4 0.41 10.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CCF50696.1 - 0.034 14.0 1.7 8.5 6.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain TatD_DNase PF01026.16 CCF50697.1 - 5e-49 166.7 0.1 6e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Rot1 PF10681.4 CCF50698.1 - 7.5e-69 231.3 3.5 9.3e-69 231.0 2.4 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Coatomer_WDAD PF04053.9 CCF50700.1 - 1.1e-136 456.2 0.0 2e-136 455.3 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 CCF50700.1 - 4.8e-83 279.0 0.0 7.8e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCF50700.1 - 4.5e-55 181.6 5.6 6.7e-11 41.6 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCF50700.1 - 0.0076 14.4 6.1 0.074 11.1 0.1 3.4 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.15 CCF50700.1 - 0.027 14.0 0.1 0.099 12.2 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS DUF1712 PF08217.6 CCF50701.1 - 1e-08 33.9 0.0 3.7e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) NADase_NGA PF07461.6 CCF50701.1 - 0.11 11.1 0.1 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) GDC-P PF02347.11 CCF50702.1 - 6.5e-184 611.5 0.0 8e-170 565.1 0.0 3.0 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CCF50702.1 - 2.1e-06 27.1 0.0 4.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCF50702.1 - 6.9e-05 21.7 0.2 0.00026 19.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V B3_4 PF03483.12 CCF50703.1 - 2.7e-26 92.1 0.0 4.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CCF50703.1 - 3.6e-18 65.1 0.0 1.2e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 CCF50703.1 - 0.17 11.0 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) EST1_DNA_bind PF10373.4 CCF50704.1 - 2.7e-34 118.6 0.0 1.2e-33 116.4 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCF50704.1 - 2e-10 40.7 0.0 7.3e-10 38.9 0.0 2.1 1 0 0 1 1 1 1 Telomerase activating protein Est1 Methyltrans_RNA PF04452.9 CCF50704.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Piwi PF02171.12 CCF50705.1 - 3.6e-78 262.6 0.0 5.7e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCF50705.1 - 1.3e-16 60.0 0.0 2.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 CCF50705.1 - 3e-10 39.3 0.0 3.7e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) DUF2461 PF09365.5 CCF50706.1 - 4.7e-73 245.0 0.2 9.1e-73 244.1 0.1 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) TSGP1 PF07771.6 CCF50706.1 - 0.015 15.1 1.0 0.035 13.9 0.7 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Proteasome PF00227.21 CCF50707.1 - 7.5e-36 123.1 0.0 9e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit SAMP PF05924.6 CCF50707.1 - 0.069 12.2 0.8 0.13 11.4 0.5 1.4 1 0 0 1 1 1 0 SAMP Motif Mis12 PF05859.7 CCF50708.1 - 1.1e-18 67.4 0.1 2.7e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 Mis12 protein TMEM61 PF15105.1 CCF50708.1 - 0.32 10.5 5.0 14 5.1 1.9 2.6 2 1 0 2 2 2 0 TMEM61 protein family FA_hydroxylase PF04116.8 CCF50709.1 - 7.6e-11 42.4 10.2 7.6e-11 42.4 7.1 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PI3_PI4_kinase PF00454.22 CCF50710.1 - 4.2e-47 160.5 0.0 8.4e-47 159.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CCF50710.1 - 5.8e-30 104.0 0.2 2.2e-29 102.1 0.2 2.1 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CCF50710.1 - 2.2e-07 30.1 0.1 5.8e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain PDH PF02153.12 CCF50711.1 - 7.4e-14 51.2 0.0 1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 CCF50711.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCF50711.1 - 2.8e-05 24.4 0.0 9.6e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CCF50711.1 - 0.00036 20.6 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CCF50711.1 - 0.003 17.0 0.0 0.0075 15.7 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 CCF50711.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CCF50711.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCF50711.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 CCF50711.1 - 0.14 11.7 0.0 0.69 9.5 0.0 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1777 PF08648.7 CCF50712.1 - 1.7e-24 86.5 29.4 1.7e-24 86.5 20.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) NDUF_B4 PF07225.7 CCF50713.1 - 0.00011 21.9 0.1 0.00013 21.7 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PX PF00787.19 CCF50714.1 - 4.6e-07 29.6 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Melibiase PF02065.13 CCF50715.1 - 5.5e-10 38.5 0.1 0.00045 19.0 0.0 2.0 2 0 0 2 2 2 2 Melibiase CFEM PF05730.6 CCF50717.1 - 5.3e-06 26.1 10.5 8.3e-06 25.5 7.3 1.3 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 CCF50717.1 - 1.2 9.2 8.2 2.2 8.4 5.7 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain DUF761 PF05553.6 CCF50718.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Cotton fibre expressed protein AA_permease PF00324.16 CCF50719.1 - 2.1e-114 382.5 40.8 2.5e-114 382.2 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF50719.1 - 4.8e-35 120.9 41.1 5.8e-35 120.6 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1989 PF09347.5 CCF50720.1 - 1.6e-52 177.3 0.0 2e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) HMA PF00403.21 CCF50723.1 - 1.1e-15 57.5 0.9 1.3e-15 57.3 0.6 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain YtkA PF13115.1 CCF50723.1 - 0.076 13.3 0.8 0.16 12.3 0.4 1.6 2 0 0 2 2 2 0 YtkA-like UPF0004 PF00919.15 CCF50723.1 - 0.087 12.6 0.1 0.1 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 HA2 PF04408.18 CCF50724.1 - 1.5e-24 85.9 0.3 6.2e-24 83.9 0.0 2.3 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCF50724.1 - 2.7e-22 78.7 0.0 3.1e-21 75.3 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCF50724.1 - 4.6e-12 45.6 0.0 1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF50724.1 - 1e-07 31.6 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF50724.1 - 3.2e-06 27.3 0.1 9.3e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCF50724.1 - 0.0018 17.2 0.0 0.0052 15.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 CCF50724.1 - 0.0063 16.4 0.1 0.055 13.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CCF50724.1 - 0.022 14.5 0.0 9.1 6.0 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 CCF50724.1 - 0.024 14.3 0.2 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CCF50724.1 - 0.024 14.6 0.0 0.094 12.7 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCF50724.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CCF50724.1 - 0.034 14.4 0.0 0.097 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CCF50724.1 - 0.037 13.7 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 CCF50724.1 - 0.049 12.7 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 CCF50724.1 - 0.077 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein p450 PF00067.17 CCF50725.1 - 6.5e-64 216.1 0.0 1.4e-56 192.0 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Perilipin PF03036.11 CCF50727.1 - 3.9e-10 39.1 0.2 1.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 CCF50727.1 - 0.00038 20.0 0.1 0.00079 18.9 0.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_32 PF13654.1 CCF50727.1 - 0.0039 15.9 2.0 0.0053 15.4 1.4 1.1 1 0 0 1 1 1 1 AAA domain LIF_OSM PF01291.12 CCF50727.1 - 0.023 14.6 0.1 0.055 13.3 0.1 1.8 1 1 0 1 1 1 0 LIF / OSM family HMG_CoA_synt_C PF08540.5 CCF50727.1 - 0.026 14.0 0.5 0.044 13.2 0.3 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal c-SKI_SMAD_bind PF08782.5 CCF50727.1 - 0.049 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 c-SKI Smad4 binding domain AAA PF00004.24 CCF50729.1 - 1.4e-56 190.3 0.0 1.9e-43 147.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCF50729.1 - 7.4e-26 90.0 0.1 1.7e-25 88.8 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CCF50729.1 - 8.2e-13 48.7 3.4 7.1e-06 26.1 0.0 4.6 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CCF50729.1 - 2.2e-09 38.1 0.0 0.0033 18.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCF50729.1 - 6.6e-09 35.4 4.0 0.026 13.9 0.0 4.5 2 2 2 4 4 4 3 AAA domain AAA_18 PF13238.1 CCF50729.1 - 1.1e-07 32.2 0.0 0.0014 18.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCF50729.1 - 1.7e-07 31.4 1.4 0.064 13.4 0.0 4.3 3 2 1 4 4 3 2 AAA domain AAA_19 PF13245.1 CCF50729.1 - 6e-07 29.1 0.1 0.0024 17.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 CCF50729.1 - 1.1e-06 27.9 0.1 0.003 16.6 0.0 3.0 4 0 0 4 4 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCF50729.1 - 3.6e-06 26.8 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCF50729.1 - 4.4e-06 26.4 0.0 0.068 12.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCF50729.1 - 8.3e-06 25.7 0.0 0.06 13.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CCF50729.1 - 1.5e-05 24.2 0.1 0.053 12.6 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 CCF50729.1 - 2.8e-05 24.2 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 CCF50729.1 - 3.8e-05 22.9 0.2 0.15 11.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCF50729.1 - 3.8e-05 23.7 0.2 0.061 13.2 0.1 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CCF50729.1 - 5.5e-05 22.7 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 CCF50729.1 - 8.8e-05 22.5 0.0 0.19 11.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain TIP49 PF06068.8 CCF50729.1 - 0.00011 21.0 0.0 0.09 11.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus NACHT PF05729.7 CCF50729.1 - 0.00025 20.7 1.1 0.57 9.8 0.1 3.9 3 1 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 CCF50729.1 - 0.00085 18.9 0.0 0.16 11.6 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CCF50729.1 - 0.00099 19.0 0.1 0.79 9.5 0.0 3.1 3 0 0 3 3 3 1 Shikimate kinase AAA_3 PF07726.6 CCF50729.1 - 0.0013 18.3 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCF50729.1 - 0.0017 17.3 0.1 2 7.3 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CCF50729.1 - 0.0021 18.0 0.0 0.047 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CCF50729.1 - 0.0024 17.3 0.0 0.7 9.2 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 CCF50729.1 - 0.0053 16.4 0.1 0.37 10.4 0.0 2.6 2 0 0 2 2 2 1 NTPase KaiC PF06745.8 CCF50729.1 - 0.016 14.3 0.2 5.6 6.0 0.0 2.7 3 0 0 3 3 3 0 KaiC Cytidylate_kin2 PF13189.1 CCF50729.1 - 0.017 15.0 0.1 0.5 10.2 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase-like family AAA_24 PF13479.1 CCF50729.1 - 0.027 14.0 1.8 4.2 6.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 CCF50729.1 - 0.029 13.3 0.0 0.15 11.0 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.17 CCF50729.1 - 0.03 13.1 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain KTI12 PF08433.5 CCF50729.1 - 0.032 13.4 2.6 0.22 10.6 0.1 3.0 3 1 1 4 4 4 0 Chromatin associated protein KTI12 Rad17 PF03215.10 CCF50729.1 - 0.11 11.1 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Zot PF05707.7 CCF50729.1 - 0.25 10.7 1.3 12 5.2 0.3 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) eRF1_2 PF03464.10 CCF50730.1 - 2.1e-45 154.3 0.3 4.5e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 CCF50730.1 - 1.4e-37 128.3 0.1 2.6e-37 127.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCF50730.1 - 1.3e-25 89.5 0.0 2.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 DUF4202 PF13875.1 CCF50731.1 - 1.5e-63 213.7 0.0 3.3e-63 212.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_23 PF13489.1 CCF50731.1 - 2.5e-16 59.8 0.0 6.5e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF50731.1 - 5.4e-12 46.0 0.0 2.7e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF50731.1 - 4.3e-10 39.8 0.0 9.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF50731.1 - 9.9e-10 38.7 0.0 2.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF50731.1 - 2.1e-08 33.9 0.0 6.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF50731.1 - 9.4e-08 32.6 0.0 2.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF50731.1 - 1.7e-05 24.7 0.0 6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCF50731.1 - 0.00016 20.7 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.9 CCF50731.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 CCF50731.1 - 0.0044 17.8 0.0 0.013 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 CCF50731.1 - 0.045 12.4 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DUF1754 PF08555.5 CCF50732.1 - 2e-17 63.5 16.4 3e-17 62.9 11.4 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF4349 PF14257.1 CCF50732.1 - 0.044 13.0 5.0 0.059 12.5 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Asp-B-Hydro_N PF05279.6 CCF50732.1 - 0.082 12.7 9.8 0.098 12.4 6.8 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TMEM237 PF15383.1 CCF50732.1 - 0.14 11.2 5.2 0.17 10.9 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Sigma70_ner PF04546.8 CCF50732.1 - 0.27 10.8 10.5 0.33 10.5 7.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SpoIIIAH PF12685.2 CCF50732.1 - 0.36 10.3 11.7 0.45 9.9 8.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Vfa1 PF08432.5 CCF50732.1 - 0.55 10.2 13.4 0.68 9.9 9.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SOBP PF15279.1 CCF50732.1 - 0.55 10.5 7.9 0.62 10.3 5.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2413 PF10310.4 CCF50732.1 - 1.6 7.4 11.9 1.9 7.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2317 PF10079.4 CCF50732.1 - 2.1 6.8 7.9 2.6 6.5 5.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) PGA2 PF07543.7 CCF50732.1 - 3.2 7.5 10.7 4.5 7.0 7.4 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 DDHD PF02862.12 CCF50732.1 - 3.3 7.4 10.5 3.9 7.1 7.2 1.1 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.1 CCF50732.1 - 4.2 5.4 4.7 5 5.1 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1510 PF07423.6 CCF50732.1 - 8.8 5.6 14.0 12 5.2 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 CCF50732.1 - 9.1 5.1 14.8 11 4.8 10.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.2 CCF50732.1 - 9.8 3.7 9.8 11 3.6 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OST3_OST6 PF04756.8 CCF50733.1 - 7.6e-20 71.0 1.0 7.6e-20 71.0 0.7 1.9 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 CCF50733.1 - 0.00024 20.7 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HlyIII PF03006.15 CCF50733.1 - 0.0024 17.3 4.6 0.013 14.9 0.8 2.5 2 0 0 2 2 2 2 Haemolysin-III related Transp_cyt_pur PF02133.10 CCF50734.1 - 4.1e-32 111.2 28.4 5.9e-32 110.7 19.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Dynamitin PF04912.9 CCF50735.1 - 4e-41 141.1 1.7 1.2e-40 139.5 1.1 1.7 1 1 0 1 1 1 1 Dynamitin DUF3584 PF12128.3 CCF50735.1 - 0.12 9.7 9.0 0.0051 14.2 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4164 PF13747.1 CCF50735.1 - 3.2 7.9 18.5 0.069 13.2 4.9 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) ADK PF00406.17 CCF50736.1 - 4.8e-44 149.8 0.1 1e-23 83.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 CCF50736.1 - 2e-07 31.3 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF50736.1 - 9.9e-06 25.4 0.0 6.4e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF50736.1 - 1.3e-05 26.0 0.0 2.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCF50736.1 - 0.00014 21.3 0.1 0.33 10.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 CCF50736.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin BCS1_N PF08740.6 CCF50737.1 - 1.4e-56 191.1 0.0 2e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCF50737.1 - 4.6e-17 62.4 0.0 8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCF50737.1 - 1.2e-05 26.1 0.0 3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCF50737.1 - 0.00038 19.9 0.0 0.0027 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCF50737.1 - 0.0054 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCF50737.1 - 0.0059 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CCF50737.1 - 0.022 14.5 0.2 0.16 11.7 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 CCF50737.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CHAT PF12770.2 CCF50737.1 - 0.052 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 CHAT domain AAA_18 PF13238.1 CCF50737.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CCF50737.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 CCF50737.1 - 0.19 11.7 4.1 0.092 12.7 0.3 2.5 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_3 PF01171.15 CCF50738.1 - 3.7e-15 55.9 0.0 1.1e-14 54.3 0.0 1.8 1 1 0 1 1 1 1 PP-loop family MU117 PF15474.1 CCF50738.1 - 0.0081 16.6 0.6 0.34 11.4 0.2 2.6 2 0 0 2 2 2 1 Meiotically up-regulated gene family HIPIP PF01355.12 CCF50738.1 - 0.21 11.7 4.7 10 6.3 0.3 3.0 3 0 0 3 3 3 0 High potential iron-sulfur protein DUF2616 PF11077.3 CCF50738.1 - 2.6 7.5 6.2 2.5 7.5 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PEMT PF04191.8 CCF50739.1 - 0.00074 19.5 0.1 0.0038 17.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CCF50739.1 - 0.0049 17.0 0.0 0.41 10.8 0.0 2.2 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family WD40 PF00400.27 CCF50740.1 - 7e-54 177.9 20.8 1.2e-08 34.4 0.1 8.1 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CCF50740.1 - 9.1e-06 24.0 6.1 0.076 11.1 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 UCH PF00443.24 CCF50741.1 - 2.5e-76 256.3 0.0 3.9e-76 255.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CCF50741.1 - 3.8e-19 68.9 0.0 1.2e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.1 CCF50741.1 - 2.9e-16 59.7 0.0 5.7e-09 35.8 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CCF50741.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal VP4_haemagglut PF00426.13 CCF50741.1 - 0.23 9.4 0.1 0.34 8.8 0.0 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Zn-ribbon_8 PF09723.5 CCF50741.1 - 0.42 10.6 2.9 3.5 7.6 0.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Velvet PF11754.3 CCF50744.1 - 4.5e-58 196.2 0.0 7.6e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Velvet PF11754.3 CCF50745.1 - 7.6e-24 84.4 0.0 2.3e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 Velvet factor GP4 PF03010.9 CCF50747.1 - 0.28 10.7 0.8 0.9 9.1 0.4 1.9 2 0 0 2 2 2 0 GP4 4HBT PF03061.17 CCF50748.1 - 9.5e-11 41.6 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 CCF50748.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Fungal_trans PF04082.13 CCF50750.1 - 1.4e-07 30.6 0.3 8.2e-07 28.1 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF50750.1 - 3.6e-07 29.9 11.2 8.4e-07 28.8 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRM PF02005.11 CCF50751.1 - 2.1e-115 385.6 0.0 4.3e-88 295.7 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF4557 PF15101.1 CCF50751.1 - 0.14 11.9 7.6 0.52 10.1 5.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CCF50751.1 - 0.15 10.2 13.5 0.25 9.5 9.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_III_AF PF09581.5 CCF50751.1 - 2.6 7.8 5.5 14 5.4 3.6 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Spore_coat_CotO PF14153.1 CCF50751.1 - 6.6 6.1 11.2 18 4.7 7.8 1.7 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.9 CCF50751.1 - 8.4 6.3 7.8 80 3.2 5.4 2.3 1 1 0 1 1 1 0 RNA polymerase III RPC4 zf-NADH-PPase PF09297.6 CCF50752.1 - 0.0016 17.8 1.5 0.0016 17.8 1.0 2.0 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain zf-FPG_IleRS PF06827.9 CCF50752.1 - 0.038 13.6 4.1 1.8 8.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.2 CCF50752.1 - 0.057 13.2 3.0 0.2 11.4 2.1 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.2 CCF50752.1 - 0.43 10.4 3.2 1.5 8.6 2.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.8 CCF50752.1 - 1.1 8.8 3.6 0.44 10.0 0.2 2.1 2 0 0 2 2 2 0 InsA N-terminal domain CM_2 PF01817.16 CCF50753.1 - 2.7e-07 30.5 0.1 0.00029 20.8 0.0 3.9 2 1 1 3 3 3 2 Chorismate mutase type II NIF PF03031.13 CCF50754.1 - 1.1e-20 73.9 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 CCF50754.1 - 0.0016 17.8 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCF50754.1 - 0.12 12.6 0.2 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Cyclin PF08613.6 CCF50755.1 - 3.9e-10 40.3 0.0 1.5e-09 38.4 0.0 2.1 1 0 0 1 1 1 1 Cyclin Gly-zipper_Omp PF13488.1 CCF50756.1 - 0.93 9.1 41.7 0.78 9.4 5.9 4.7 4 0 0 4 4 4 0 Glycine zipper DUF456 PF04306.8 CCF50756.1 - 1.7 8.6 10.1 0.18 11.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 CCF50756.1 - 2.2 7.9 37.3 0.48 10.1 4.5 4.6 4 0 0 4 4 4 0 Glycine-zipper containing OmpA-like membrane domain DAO PF01266.19 CCF50757.1 - 5.4e-15 55.1 0.4 2e-14 53.2 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CCF50757.1 - 2.1e-14 53.5 0.1 6.6e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCF50757.1 - 9.1e-13 48.0 0.2 9.1e-13 48.0 0.1 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCF50757.1 - 4e-06 26.8 0.0 2.2e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF50757.1 - 1.4e-05 24.1 1.5 2.8e-05 23.1 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CCF50757.1 - 7.7e-05 21.3 0.3 0.00037 19.1 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCF50757.1 - 0.00023 20.9 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CCF50757.1 - 0.00078 18.6 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 CCF50757.1 - 0.001 18.5 0.3 0.0019 17.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDI PF00996.13 CCF50757.1 - 0.0043 15.4 0.0 1.2 7.3 0.0 2.3 2 0 0 2 2 2 2 GDP dissociation inhibitor Rossmann-like PF10727.4 CCF50757.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain Pyr_redox_3 PF13738.1 CCF50757.1 - 0.0051 16.9 0.0 0.056 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF50757.1 - 0.0056 15.8 0.1 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CCF50757.1 - 0.0062 16.9 3.1 0.053 13.9 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCF50757.1 - 0.0074 15.3 0.3 0.0074 15.3 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 CCF50757.1 - 0.01 14.6 2.0 0.027 13.3 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CCF50757.1 - 0.011 15.4 1.4 0.041 13.6 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Strep_67kDa_ant PF06100.6 CCF50757.1 - 0.012 14.0 0.2 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Glyco_trans_4_4 PF13579.1 CCF50757.1 - 0.023 14.8 0.7 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain 3HCDH_N PF02737.13 CCF50757.1 - 0.024 14.3 0.4 0.056 13.1 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCF50757.1 - 0.028 14.8 0.3 0.097 13.1 0.2 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 CCF50757.1 - 0.037 14.0 0.1 0.089 12.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.14 CCF50757.1 - 0.037 13.1 0.4 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_10 PF13460.1 CCF50757.1 - 0.045 13.7 1.4 0.16 11.9 0.9 2.0 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 CCF50757.1 - 0.051 13.8 1.0 0.2 11.9 0.0 2.3 3 0 0 3 3 3 0 Putative NAD(P)-binding ThiF PF00899.16 CCF50757.1 - 0.061 13.1 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 CCF50757.1 - 0.08 11.8 1.9 0.11 11.3 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 CCF50757.1 - 0.21 10.1 4.2 2.4 6.6 0.3 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Elongin_A PF06881.6 CCF50758.1 - 1.1e-33 115.8 2.2 2.1e-33 114.9 1.5 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RabGAP-TBC PF00566.13 CCF50759.1 - 1.2e-41 142.5 0.0 2.3e-41 141.6 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glutaredoxin PF00462.19 CCF50760.1 - 8.2e-18 64.1 0.0 2.3e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCF50760.1 - 1.7e-14 53.3 0.0 3.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CCF50760.1 - 0.0011 18.7 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_8 PF13905.1 CCF50760.1 - 0.0016 18.5 0.1 0.062 13.4 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.6 CCF50760.1 - 0.016 15.0 0.0 0.28 11.1 0.0 2.6 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE ArsC PF03960.10 CCF50760.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 ArsC family SH3BGR PF04908.10 CCF50760.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Methyltransf_16 PF10294.4 CCF50761.1 - 1.5e-19 70.1 0.1 9.6e-12 44.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 CCF50761.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF50761.1 - 4.1e-06 27.3 0.0 6.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF50761.1 - 0.00055 19.9 0.0 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CCF50761.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 CCF50761.1 - 0.046 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCF50761.1 - 0.049 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CCF50761.1 - 0.075 12.6 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CCF50761.1 - 0.13 12.7 0.0 0.53 10.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Nuf2 PF03800.9 CCF50762.1 - 1e-41 142.3 0.0 1e-41 142.3 0.0 3.2 4 1 0 4 4 4 1 Nuf2 family GM_CSF PF01109.12 CCF50762.1 - 0.00041 20.2 1.4 0.00041 20.2 1.0 2.4 2 1 0 3 3 3 1 Granulocyte-macrophage colony-stimulating factor Reo_sigmaC PF04582.7 CCF50762.1 - 0.065 12.4 9.6 0.037 13.2 2.5 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1638 PF07796.6 CCF50762.1 - 0.41 10.2 8.0 1.9 8.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1638) ATP-synt_G PF04718.10 CCF50762.1 - 5.9 7.6 12.2 0.54 10.9 0.2 3.9 1 1 3 4 4 4 0 Mitochondrial ATP synthase g subunit DUF3405 PF11885.3 CCF50763.1 - 5.7e-91 305.2 0.1 4.5e-49 167.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) COG4 PF08318.7 CCF50764.1 - 8.9e-57 192.3 0.0 5.3e-56 189.7 0.0 2.0 1 1 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.8 CCF50764.1 - 0.0091 14.5 0.1 0.05 12.1 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family TIP49 PF06068.8 CCF50765.1 - 7.2e-181 601.2 1.6 8.5e-181 600.9 1.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCF50765.1 - 8.3e-08 32.5 1.3 2.2e-05 24.6 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 CCF50765.1 - 1.3e-06 27.4 0.3 2.6e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.7 CCF50765.1 - 1.4e-06 27.5 3.6 0.00066 18.7 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCF50765.1 - 5e-05 23.2 0.1 3 7.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_22 PF13401.1 CCF50765.1 - 0.00015 21.9 0.2 0.73 9.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF50765.1 - 0.00033 20.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CCF50765.1 - 0.00071 19.0 0.3 0.0019 17.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCF50765.1 - 0.0016 17.6 1.4 0.041 13.0 0.2 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCF50765.1 - 0.0034 17.1 0.7 1.2 8.8 0.0 3.2 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CCF50765.1 - 0.02 14.8 0.1 0.06 13.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sipho_tail PF05709.6 CCF50765.1 - 0.02 14.0 0.1 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Sigma54_activat PF00158.21 CCF50765.1 - 0.036 13.5 0.1 6.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 CCF50765.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ATP-synt_ab PF00006.20 CCF50765.1 - 0.064 12.7 0.1 0.085 12.3 0.1 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 CCF50765.1 - 0.099 13.4 0.0 0.41 11.4 0.0 2.3 1 1 0 2 2 2 0 AAA domain DUF1713 PF08213.6 CCF50766.1 - 7.8e-10 38.1 25.3 7.8e-10 38.1 17.6 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) CDK2AP PF09806.4 CCF50766.1 - 0.00073 19.8 5.6 0.0013 18.9 3.9 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Syntaxin PF00804.20 CCF50767.1 - 6.1e-15 55.2 4.0 6.1e-15 55.2 2.8 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 CCF50767.1 - 3.1e-11 42.8 7.3 3.1e-11 42.8 5.1 2.7 3 0 0 3 3 3 1 SNARE domain MCPsignal PF00015.16 CCF50767.1 - 0.0029 17.2 10.7 0.021 14.3 2.2 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.6 CCF50767.1 - 0.0093 13.5 8.5 0.12 9.8 0.1 2.1 2 0 0 2 2 2 2 Prominin DUF2077 PF09850.4 CCF50767.1 - 0.02 14.2 0.1 0.02 14.2 0.1 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) TB2_DP1_HVA22 PF03134.14 CCF50767.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DUF4094 PF13334.1 CCF50767.1 - 0.027 14.8 0.3 0.027 14.8 0.2 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) Allexi_40kDa PF05549.6 CCF50767.1 - 0.044 13.0 8.0 0.034 13.4 1.4 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein PBP1_TM PF14812.1 CCF50767.1 - 0.065 13.5 0.1 0.065 13.5 0.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Synaptobrevin PF00957.16 CCF50767.1 - 0.53 9.9 11.9 0.15 11.7 2.3 2.8 2 1 0 2 2 2 0 Synaptobrevin Spectrin PF00435.16 CCF50767.1 - 0.93 9.8 11.2 1.5 9.1 0.2 3.3 2 1 0 2 2 2 0 Spectrin repeat Tropomyosin PF00261.15 CCF50767.1 - 1.5 7.8 17.7 2.1 7.3 4.8 3.0 1 1 2 3 3 3 0 Tropomyosin T2SF PF00482.18 CCF50767.1 - 7.6 6.4 9.2 22 4.9 2.5 3.3 2 2 2 4 4 4 0 Type II secretion system (T2SS), protein F Transposase_20 PF02371.11 CCF50768.1 - 0.025 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family DUF4167 PF13763.1 CCF50769.1 - 0.078 13.0 0.2 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) DUF3535 PF12054.3 CCF50770.1 - 8.5e-124 413.5 5.6 1.1e-122 409.8 0.3 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CCF50770.1 - 5.6e-71 238.7 0.0 8.4e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF50770.1 - 6.3e-13 48.3 0.0 2e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 CCF50770.1 - 1.8e-10 39.9 38.2 0.06 13.4 0.0 11.5 13 0 0 13 13 13 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CCF50770.1 - 5.1e-06 26.7 0.2 0.22 11.9 0.0 3.0 2 1 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCF50770.1 - 0.084 13.3 45.0 3.2 8.3 1.2 11.5 12 1 1 13 13 13 0 HEAT-like repeat Ribosomal_L18e PF00828.14 CCF50771.1 - 1.7e-22 80.1 0.1 4.6e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Utp21 PF04192.7 CCF50772.1 - 2.1e-48 164.4 0.0 4.5e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCF50772.1 - 1.9e-14 52.9 10.4 3e-05 23.7 0.1 8.0 7 1 1 8 8 8 3 WD domain, G-beta repeat PQQ_2 PF13360.1 CCF50772.1 - 3.8e-06 26.5 0.6 0.00059 19.3 0.1 2.7 2 0 0 2 2 2 2 PQQ-like domain Apc4_WD40 PF12894.2 CCF50772.1 - 0.045 13.2 0.0 5.7 6.5 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 CCF50772.1 - 0.51 10.6 2.4 7.2 7.0 0.1 4.0 6 0 0 6 6 6 0 PQQ-like domain DEAD PF00270.24 CCF50773.1 - 5.9e-43 146.2 0.0 1.1e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCF50773.1 - 6.1e-21 73.7 0.2 1.6e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCF50773.1 - 1.7e-19 69.4 0.0 3.3e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hist_deacetyl PF00850.14 CCF50774.1 - 4.3e-71 239.7 0.0 9.7e-71 238.5 0.0 1.6 1 1 0 1 1 1 1 Histone deacetylase domain Glyco_tran_28_C PF04101.11 CCF50774.1 - 0.021 14.4 0.1 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DNA_pol_viral_N PF00242.12 CCF50774.1 - 1.3 7.9 7.4 2.1 7.3 5.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Fungal_trans PF04082.13 CCF50776.1 - 3.8e-17 62.0 1.6 7.2e-17 61.1 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF50776.1 - 3.1e-05 23.8 10.2 7.1e-05 22.6 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.9 CCF50776.1 - 0.21 9.6 10.0 0.42 8.5 6.9 1.5 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 CCF50776.1 - 2.2 6.3 2.9 3.4 5.6 2.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.7 CCF50776.1 - 10 4.1 6.5 19 3.1 4.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Methyltransf_28 PF02636.12 CCF50777.1 - 2.5e-70 236.7 0.0 4.4e-70 235.9 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Amino_oxidase PF01593.19 CCF50777.1 - 5.6e-15 55.3 0.5 1.4e-14 54.0 0.3 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCF50777.1 - 1.3e-11 44.3 0.1 4.1e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF50777.1 - 7.9e-09 34.8 0.0 3.4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF50777.1 - 5.5e-05 21.8 0.1 0.033 12.6 0.1 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 CCF50777.1 - 0.00016 21.5 0.8 0.029 14.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCF50777.1 - 0.0029 17.6 0.2 4.5 7.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCF50777.1 - 0.0061 15.2 0.0 0.7 8.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 CCF50777.1 - 0.023 15.0 0.4 5 7.6 0.0 3.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UCR_14kD PF02271.11 CCF50778.1 - 3.8e-39 132.6 0.8 4.4e-39 132.4 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit YIF1 PF03878.10 CCF50779.1 - 2.1e-78 262.7 0.4 2.9e-78 262.3 0.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CCF50779.1 - 0.025 14.0 11.1 0.097 12.1 7.8 1.8 1 1 0 1 1 1 0 Yip1 domain eIF-1a PF01176.14 CCF50780.1 - 8.6e-28 95.5 0.1 1.2e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Solute_trans_a PF03619.11 CCF50781.1 - 1.5e-99 332.8 7.9 1.8e-99 332.5 5.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mit_ribos_Mrp51 PF11709.3 CCF50782.1 - 9.2e-14 51.3 0.7 3.3e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein subunit OMPdecase PF00215.19 CCF50783.1 - 9e-73 244.3 0.0 1.1e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family SelA PF03841.8 CCF50783.1 - 0.11 11.2 0.1 0.46 9.1 0.0 1.8 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase HhH-GPD PF00730.20 CCF50784.1 - 9.2e-18 64.5 0.0 1.7e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCF50784.1 - 2.8e-08 33.0 0.0 1.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CCF50784.1 - 0.036 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain GTP_EFTU PF00009.22 CCF50785.1 - 9.8e-44 149.0 0.0 1.9e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CCF50785.1 - 1.8e-10 40.7 3.9 3.8e-10 39.7 2.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 CCF50785.1 - 9.8e-09 35.2 2.3 1.8e-08 34.3 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 CCF50785.1 - 1.3e-07 31.6 0.1 3.1e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CCF50785.1 - 3.9e-06 26.8 0.0 9.3e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CCF50785.1 - 1.2e-05 24.8 0.6 3e-05 23.5 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CCF50785.1 - 0.016 15.7 0.0 0.13 12.7 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CCF50785.1 - 0.026 13.7 0.0 1.5 7.9 0.0 2.3 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit cobW PF02492.14 CCF50785.1 - 0.049 13.0 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CCF50785.1 - 0.17 10.8 0.0 0.45 9.4 0.0 1.6 2 0 0 2 2 2 0 Septin YqeY PF09424.5 CCF50786.1 - 1.9e-15 56.9 4.2 2.5e-15 56.5 2.9 1.1 1 0 0 1 1 1 1 Yqey-like protein CM_2 PF01817.16 CCF50786.1 - 0.015 15.3 1.9 0.02 14.9 0.7 1.6 2 0 0 2 2 2 0 Chorismate mutase type II RepB-RCR_reg PF10723.4 CCF50786.1 - 0.53 10.0 3.6 0.97 9.2 2.5 1.5 1 1 0 1 1 1 0 Replication regulatory protein RepB Kinesin PF00225.18 CCF50787.1 - 8.6e-113 376.4 1.6 1e-112 376.1 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF465 PF04325.8 CCF50787.1 - 8.1e-13 47.8 4.1 8.1e-13 47.8 2.9 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF465) HOOK PF05622.7 CCF50787.1 - 0.0017 16.2 37.4 0.0017 16.2 25.9 3.3 1 1 2 3 3 3 2 HOOK protein Filament PF00038.16 CCF50787.1 - 0.002 17.6 44.8 0.002 17.6 31.1 3.9 3 1 1 4 4 4 1 Intermediate filament protein Asp PF00026.18 CCF50788.1 - 0.56 9.4 1.8 8.4 5.5 0.8 2.2 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Fungal_trans PF04082.13 CCF50789.1 - 1.1e-24 86.7 0.0 1.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF50789.1 - 1.1e-09 38.0 1.6 1.9e-09 37.2 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S21 PF01165.15 CCF50792.1 - 8.2e-12 44.3 8.3 1.6e-11 43.4 5.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 MIF4G PF02854.14 CCF50793.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain COesterase PF00135.23 CCF50795.1 - 3.7e-96 322.9 0.0 5.1e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF50795.1 - 1.7e-11 44.0 0.2 3.9e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCF50795.1 - 2.6e-06 26.8 0.0 5.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCF50795.1 - 0.056 13.2 0.2 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Defensin_propep PF00879.13 CCF50796.1 - 0.36 10.8 1.8 0.87 9.5 0.0 2.6 2 0 0 2 2 2 0 Defensin propeptide Adaptin_N PF01602.15 CCF50797.1 - 7.3e-138 460.1 9.9 9.1e-138 459.8 6.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCF50797.1 - 3.1e-26 92.3 5.7 1.2e-24 87.0 1.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCF50797.1 - 9.3e-16 57.8 9.8 9e-09 35.4 0.2 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 CCF50797.1 - 8.4e-10 37.8 0.4 0.017 15.1 0.0 4.7 3 0 0 3 3 3 3 HEAT repeat CLASP_N PF12348.3 CCF50797.1 - 6.1e-05 22.4 0.4 0.49 9.6 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 CCF50797.1 - 0.00016 21.3 2.4 0.61 9.9 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 CCF50797.1 - 0.00041 19.4 1.2 0.06 12.3 0.0 2.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CCF50797.1 - 0.0016 18.8 6.6 0.48 10.9 0.1 5.7 5 1 1 6 6 6 1 HEAT-like repeat FANCI_S2 PF14676.1 CCF50797.1 - 0.25 11.2 2.8 0.26 11.1 0.1 2.3 2 2 0 2 2 2 0 FANCI solenoid 2 Ank_2 PF12796.2 CCF50798.1 - 9.3e-36 122.0 4.5 1.4e-10 41.3 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 CCF50798.1 - 5e-34 117.1 3.5 1.1e-33 116.0 2.4 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.25 CCF50798.1 - 8.1e-29 97.9 8.9 3.3e-06 26.6 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CCF50798.1 - 2.9e-25 88.1 2.7 1.2e-07 32.0 0.1 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCF50798.1 - 9.2e-25 86.1 7.1 2.4e-09 37.1 0.0 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF50798.1 - 3.3e-19 67.0 1.9 0.00044 20.2 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat gag_pre-integrs PF13976.1 CCF50799.1 - 0.017 14.7 0.3 0.031 13.8 0.0 1.7 1 1 1 2 2 2 0 GAG-pre-integrase domain DUF155 PF02582.9 CCF50800.1 - 6.4e-54 182.5 0.0 9.5e-54 181.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TRAPPC9-Trs120 PF08626.6 CCF50801.1 - 6.1e-84 282.2 0.0 3.4e-69 233.3 0.0 3.5 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GATA PF00320.22 CCF50803.1 - 2.9e-18 64.8 1.8 6.3e-18 63.8 1.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CCF50803.1 - 3.6e-14 52.0 2.6 7.5e-14 51.0 1.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ABC_tran PF00005.22 CCF50804.1 - 8.2e-47 158.9 0.0 6.2e-26 91.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCF50804.1 - 1.1e-15 58.3 0.1 0.013 15.4 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CCF50804.1 - 1.7e-11 43.7 0.2 0.0003 20.0 0.0 3.4 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 CCF50804.1 - 1.6e-09 37.2 0.9 3.4e-09 36.2 0.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 CCF50804.1 - 2.4e-06 26.9 0.2 0.061 12.8 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCF50804.1 - 7.9e-06 26.3 0.3 0.11 12.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCF50804.1 - 1e-05 25.4 0.1 0.022 14.7 0.0 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CCF50804.1 - 1.4e-05 24.3 0.1 0.1 11.6 0.1 3.5 2 1 1 3 3 3 1 AAA ATPase domain HEAT_2 PF13646.1 CCF50804.1 - 0.00015 21.9 8.1 0.87 9.9 1.4 4.8 1 1 3 4 4 4 2 HEAT repeats AAA_28 PF13521.1 CCF50804.1 - 0.00017 21.6 1.1 0.92 9.4 0.0 3.7 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CCF50804.1 - 0.00028 21.3 2.4 0.1 13.1 0.0 3.3 3 1 0 3 3 2 1 Miro-like protein DUF87 PF01935.12 CCF50804.1 - 0.00037 20.3 0.1 0.17 11.6 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 ArgK PF03308.11 CCF50804.1 - 0.0006 18.6 0.6 0.078 11.7 0.1 2.7 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 CCF50804.1 - 0.00066 19.8 0.0 1.1 9.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 CCF50804.1 - 0.00081 18.9 0.8 1.7 8.0 0.1 3.7 3 0 0 3 3 3 1 AAA-like domain HEAT_EZ PF13513.1 CCF50804.1 - 0.00081 19.8 5.3 0.17 12.4 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat DUF258 PF03193.11 CCF50804.1 - 0.0014 17.8 0.1 0.041 13.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CCF50804.1 - 0.0017 18.2 0.0 0.28 11.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCF50804.1 - 0.003 17.4 0.0 0.97 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCF50804.1 - 0.0038 18.0 0.0 1.7 9.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain CLASP_N PF12348.3 CCF50804.1 - 0.0049 16.2 0.0 7.2 5.8 0.0 3.5 3 0 0 3 3 3 0 CLASP N terminal MobB PF03205.9 CCF50804.1 - 0.0049 16.5 0.2 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCF50804.1 - 0.0078 16.2 1.4 2.6 7.9 0.2 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CCF50804.1 - 0.009 15.4 0.1 4.5 6.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CCF50804.1 - 0.011 15.5 0.2 8.4 6.0 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase NACHT PF05729.7 CCF50804.1 - 0.018 14.6 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 CCF50804.1 - 0.031 14.1 0.1 0.92 9.3 0.0 2.6 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 CCF50804.1 - 0.033 14.3 0.0 2.7 8.2 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Tudor-knot PF11717.3 CCF50804.1 - 0.055 13.1 0.8 0.13 12.0 0.6 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF3720 PF12517.3 CCF50804.1 - 0.13 12.9 5.1 0.49 11.1 3.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Sfi1 PF08457.5 CCF50805.1 - 2.5e-31 108.7 131.0 5.6e-23 81.1 71.2 2.8 1 1 1 2 2 2 2 Sfi1 spindle body protein Pkinase PF00069.20 CCF50807.1 - 2e-67 227.0 0.0 3e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF50807.1 - 5.7e-45 153.4 0.0 1.2e-44 152.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCF50807.1 - 1.1e-24 86.3 0.0 2.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CCF50807.1 - 9.1e-11 41.4 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCF50807.1 - 4.9e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CCF50807.1 - 8.4e-06 24.9 0.0 1.9e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCF50807.1 - 0.079 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CCF50807.1 - 0.41 9.4 0.0 0.67 8.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ThuA PF06283.6 CCF50808.1 - 5.8e-70 235.3 3.4 7.1e-70 235.0 2.3 1.1 1 0 0 1 1 1 1 Trehalose utilisation UTP15_C PF09384.5 CCF50809.1 - 8.5e-47 158.5 0.0 1.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCF50809.1 - 5.8e-33 111.5 5.2 3.6e-09 36.1 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Glyco_hydro_18 PF00704.23 CCF50810.1 - 3.8e-95 319.2 3.3 5.4e-95 318.7 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2034 PF10356.4 CCF50810.1 - 0.048 12.8 0.0 0.16 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2034) QRPTase_C PF01729.14 CCF50811.1 - 4.9e-50 169.3 0.1 6.1e-50 169.0 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CCF50811.1 - 4.5e-22 77.6 0.0 1.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1341 PF07071.6 CCF50811.1 - 0.036 13.6 0.0 0.074 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1341) TP6A_N PF04406.9 CCF50812.1 - 0.0005 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 CCF50812.1 - 0.0012 18.7 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) ORC6 PF05460.8 CCF50812.1 - 1.6 7.7 5.9 2.3 7.2 4.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.4 CCF50812.1 - 1.9 7.8 10.6 2.9 7.3 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAP2 PF01569.16 CCF50813.1 - 1.1e-27 96.2 1.7 1.1e-27 96.2 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.11 CCF50813.1 - 0.012 15.4 0.4 0.28 11.0 0.1 2.4 2 0 0 2 2 2 0 Colicin V production protein DUF2077 PF09850.4 CCF50813.1 - 0.051 12.9 2.8 0.43 9.9 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3464 PF11947.3 CCF50813.1 - 0.69 9.3 2.6 1.1 8.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) AtpR PF12966.2 CCF50813.1 - 8.6 6.5 9.1 8.4 6.6 1.2 2.8 3 0 0 3 3 3 0 N-ATPase, AtpR subunit APG6 PF04111.7 CCF50814.1 - 2e-94 316.1 0.0 3.2e-94 315.5 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 GLTSCR1 PF15249.1 CCF50815.1 - 2.8e-09 37.0 0.3 2.8e-09 37.0 0.2 2.3 2 1 2 4 4 4 1 Glioma tumor suppressor candidate region PEMT PF04191.8 CCF50816.1 - 6.9e-05 22.8 2.3 9.6e-05 22.4 0.5 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CCF50816.1 - 0.01 15.9 0.0 0.72 10.0 0.0 2.5 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CcoS PF03597.10 CCF50816.1 - 3.7 7.0 6.9 0.41 10.1 0.5 2.6 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type Lung_7-TM_R PF06814.8 CCF50817.1 - 8.4e-52 175.9 18.6 2.9e-51 174.1 12.9 1.8 1 1 0 1 1 1 1 Lung seven transmembrane receptor Ribosomal_L32p PF01783.18 CCF50818.1 - 3.6e-14 52.6 6.4 5.8e-14 52.0 4.4 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.1 CCF50818.1 - 0.044 13.0 0.9 0.069 12.3 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 CCF50818.1 - 0.086 12.6 0.4 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon AlaDh_PNT_N PF05222.10 CCF50819.1 - 3.6e-27 95.0 0.0 5.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCF50819.1 - 3.4e-05 23.4 0.1 0.00013 21.6 0.1 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RRM_6 PF14259.1 CCF50820.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50820.1 - 5.5e-06 25.9 0.0 8.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50820.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amidase02_C PF12123.3 CCF50820.1 - 0.015 14.9 0.1 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF605 PF04652.11 CCF50820.1 - 0.33 10.2 14.7 0.5 9.7 10.2 1.2 1 0 0 1 1 1 0 Vta1 like tRNA-synt_2 PF00152.15 CCF50821.1 - 3.5e-80 269.3 0.3 4.9e-80 268.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCF50821.1 - 3.9e-05 23.4 0.0 8.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCF50821.1 - 0.06 12.5 0.3 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-C2H2 PF00096.21 CCF50823.1 - 9.4e-09 35.1 14.5 2.5e-05 24.3 1.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF50823.1 - 2e-06 27.8 3.0 2e-06 27.8 2.1 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CCF50823.1 - 0.00029 20.9 3.1 0.01 15.9 0.2 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCF50823.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCF50823.1 - 0.0027 17.9 0.7 0.0027 17.9 0.5 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger MutS_V PF00488.16 CCF50824.1 - 1.3e-67 227.6 0.0 3.4e-67 226.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCF50824.1 - 3.4e-39 134.7 0.2 5.7e-39 134.0 0.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCF50824.1 - 2.1e-21 76.0 0.0 4.1e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCF50824.1 - 3.6e-12 46.5 0.0 4.4e-11 42.9 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CCF50824.1 - 1.2e-08 34.9 0.0 3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Prenyltrans PF00432.16 CCF50825.1 - 4.8e-47 157.1 9.7 3.6e-10 39.2 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCF50825.1 - 1.2e-30 106.1 0.0 3.9e-12 46.5 0.0 3.5 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCF50825.1 - 2e-06 27.7 0.0 0.00028 20.8 0.0 3.3 1 1 3 4 4 4 1 Prenyltransferase-like Acetyltransf_1 PF00583.19 CCF50826.1 - 3.4e-11 43.0 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCF50826.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCF50826.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF50826.1 - 0.00094 19.0 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF50826.1 - 0.0039 17.0 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF50826.1 - 0.065 13.3 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RVT_2 PF07727.9 CCF50827.1 - 2.6e-57 193.6 1.0 4.3e-57 192.9 0.7 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF50827.1 - 8.9e-13 48.4 0.3 1.7e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain RNA_pol_Rpb2_6 PF00562.23 CCF50832.1 - 2.6e-124 414.9 0.5 6.9e-124 413.4 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCF50832.1 - 4.3e-66 221.7 0.0 6.5e-66 221.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCF50832.1 - 1.2e-49 168.3 0.1 3.7e-49 166.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCF50832.1 - 2.4e-27 94.9 0.1 1.1e-26 92.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCF50832.1 - 4.4e-24 84.0 0.5 1.3e-23 82.5 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCF50832.1 - 3.3e-22 78.0 0.0 8.9e-22 76.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCF50832.1 - 1.5e-18 66.5 0.2 3.5e-18 65.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 CCF50832.1 - 0.032 14.0 0.3 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CWC25 PF12542.3 CCF50833.1 - 2.3e-25 88.8 2.3 2.3e-25 88.8 1.6 4.3 4 2 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 CCF50833.1 - 6.1e-13 48.5 14.1 6.1e-13 48.5 9.8 5.2 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ndc1_Nup PF09531.5 CCF50833.1 - 8.2 4.7 7.8 14 3.9 5.4 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTB PF00651.26 CCF50834.1 - 9.4e-08 32.0 0.0 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain ABC2_membrane PF01061.19 CCF50835.1 - 3.2e-43 147.3 17.6 3.2e-43 147.3 12.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CCF50835.1 - 9.5e-06 24.8 18.3 9.5e-06 24.8 12.7 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 CCF50835.1 - 0.0034 16.2 8.2 0.0034 16.2 5.7 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein ICL PF00463.16 CCF50836.1 - 3.8e-244 810.7 1.3 4.3e-244 810.5 0.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCF50836.1 - 1.4e-09 37.5 0.0 2.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 CCF50836.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF367 PF04034.8 CCF50837.1 - 5e-42 142.4 0.0 7.1e-42 142.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CCF50837.1 - 4.7e-15 54.8 0.1 7.9e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI MFS_1 PF07690.11 CCF50840.1 - 1.4e-29 102.9 45.5 2e-29 102.4 31.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_2 PF00328.17 CCF50841.1 - 4.8e-41 141.2 0.0 6.3e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 CCF50842.1 - 1.1e-12 48.1 0.3 2.7e-12 46.9 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF50842.1 - 1.6e-11 44.4 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CCF50842.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosomal_L41 PF05162.8 CCF50843.1 - 2.9e-09 36.4 31.2 3.1e-09 36.3 21.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 CCF50843.1 - 0.7 9.5 3.4 0.64 9.7 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) RNA_pol_Rpb6 PF01192.17 CCF50844.1 - 1.7e-24 85.3 0.3 2.2e-24 84.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Chitin_synth_1 PF01644.12 CCF50845.1 - 2.1e-73 245.4 0.2 3.2e-73 244.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCF50845.1 - 1.8e-24 85.2 0.1 4.8e-24 83.8 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCF50845.1 - 7.4e-24 84.0 0.0 7.5e-19 67.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCF50845.1 - 1.3e-13 51.0 0.4 1.3e-13 51.0 0.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF50845.1 - 3.7e-09 36.7 0.0 3.8e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RVT_2 PF07727.9 CCF50846.1 - 5.3e-06 25.5 0.1 8.7e-06 24.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YmzC PF14157.1 CCF50846.1 - 0.055 13.2 0.6 0.094 12.5 0.4 1.3 1 0 0 1 1 1 0 YmzC-like protein WD40 PF00400.27 CCF50848.1 - 9.5e-20 69.6 11.7 1.8e-05 24.4 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Zn_clus PF00172.13 CCF50849.1 - 0.00011 21.9 14.5 0.00025 20.9 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEX11 PF05648.9 CCF50850.1 - 1.9e-66 223.5 2.5 2.1e-66 223.4 1.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GTP_EFTU PF00009.22 CCF50851.1 - 1.9e-62 210.0 0.1 2.7e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCF50851.1 - 7.2e-37 125.6 0.0 2e-36 124.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CCF50851.1 - 1.5e-21 76.0 0.0 3.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCF50851.1 - 1.1e-13 50.7 0.0 2.8e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCF50851.1 - 2e-13 50.2 0.0 7.3e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF50851.1 - 4.4e-06 26.6 0.1 8.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_6 PF13516.1 CCF50852.1 - 2.1e-13 48.8 6.3 0.19 11.8 0.0 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 CCF50852.1 - 9e-10 37.9 12.1 0.04 13.5 0.0 6.7 6 2 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCF50852.1 - 5.3e-05 22.6 4.7 13 6.3 0.0 7.0 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_7 PF13504.1 CCF50852.1 - 0.0066 16.4 7.4 18 6.1 0.1 6.2 7 0 0 7 7 7 1 Leucine rich repeat DUF416 PF04222.7 CCF50852.1 - 0.038 13.1 0.0 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF416) LRR_8 PF13855.1 CCF50852.1 - 0.039 13.7 0.3 0.039 13.7 0.2 5.8 5 3 1 6 6 6 0 Leucine rich repeat DUF1751 PF08551.5 CCF50855.1 - 2.9e-29 101.2 4.6 7.8e-29 99.9 3.2 1.8 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CCF50855.1 - 0.0037 17.3 8.3 0.0075 16.3 5.8 1.5 1 0 0 1 1 1 1 Rhomboid family Spb1_C PF07780.7 CCF50856.1 - 7.6e-72 241.2 26.0 7.6e-72 241.2 18.1 4.3 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CCF50856.1 - 1.4e-52 178.2 0.2 3.3e-52 177.0 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CCF50856.1 - 1.8e-51 173.7 10.2 1.8e-51 173.7 7.0 5.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) eIF2A PF08662.6 CCF50857.1 - 1.4e-42 145.6 0.1 2.4e-37 128.5 0.0 4.5 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 CCF50857.1 - 5.5e-06 26.2 0.0 1.4e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50857.1 - 2.4e-05 23.8 0.0 7.2e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50857.1 - 0.00035 20.3 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CCF50857.1 - 0.00086 19.0 5.3 0.23 11.3 0.0 5.4 7 0 0 7 7 7 1 WD domain, G-beta repeat AAA_32 PF13654.1 CCF50857.1 - 0.098 11.2 5.9 0.16 10.6 4.1 1.2 1 0 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.2 CCF50857.1 - 0.31 10.3 9.4 0.54 9.5 6.5 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction efThoc1 PF11957.3 CCF50857.1 - 1.5 7.2 8.8 2.1 6.7 6.1 1.2 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Metal_resist PF13801.1 CCF50857.1 - 8.5 6.3 11.7 27 4.7 5.8 2.3 1 1 1 2 2 2 0 Heavy-metal resistance YtxH PF12732.2 CCF50857.1 - 9.7 6.6 7.4 3e+02 1.8 5.1 2.7 1 1 0 1 1 1 0 YtxH-like protein Complex1_LYR PF05347.10 CCF50858.1 - 0.026 14.3 0.5 0.16 11.7 0.2 2.2 2 1 0 2 2 2 0 Complex 1 protein (LYR family) DUF4219 PF13961.1 CCF50860.1 - 0.03 13.7 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 CCF50860.1 - 0.082 12.4 1.0 0.32 10.5 0.4 2.2 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Paramyxo_ncap PF00973.14 CCF50860.1 - 0.35 9.5 2.2 0.41 9.2 1.1 1.4 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Ipi1_N PF12333.3 CCF50861.1 - 2.9e-14 52.8 4.7 2.8e-10 40.0 0.1 4.6 3 1 1 4 4 4 3 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 CCF50861.1 - 0.0089 16.2 0.5 0.28 11.5 0.1 3.0 3 0 0 3 3 3 1 HEAT repeats Sel1 PF08238.7 CCF50862.1 - 6.4e-15 55.2 8.7 0.00065 20.2 0.1 6.1 6 0 0 6 6 6 4 Sel1 repeat TPR_5 PF12688.2 CCF50862.1 - 0.019 14.9 0.3 22 5.1 0.0 3.6 3 0 0 3 3 3 0 Tetratrico peptide repeat MIT PF04212.13 CCF50862.1 - 0.1 12.4 0.5 9.9 6.1 0.0 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Lactamase_B_2 PF12706.2 CCF50863.1 - 3.9e-13 49.3 0.0 6.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF50863.1 - 1.9e-10 40.7 0.0 3.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_hydro_62 PF03664.8 CCF50866.1 - 4.9e-133 442.3 7.7 5.7e-133 442.1 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Pro_isomerase PF00160.16 CCF50867.1 - 1.2e-50 171.7 0.2 6.5e-50 169.3 0.0 2.1 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CCF50867.1 - 1.3e-05 24.9 5.8 0.002 17.9 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Mito_carr PF00153.22 CCF50868.1 - 1.3e-46 156.2 10.9 9.9e-16 57.2 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein CH PF00307.26 CCF50870.1 - 6.7e-41 138.6 0.0 9.4e-22 77.1 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 CCF50870.1 - 1.7e-20 72.7 0.0 5e-20 71.2 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 CCF50870.1 - 2.4e-13 49.5 0.1 4.3e-09 35.8 0.0 3.2 3 1 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 CCF50870.1 - 6.6e-06 26.3 4.0 0.0001 22.5 0.2 3.0 2 0 0 2 2 2 1 Spectrin repeat EF-hand_6 PF13405.1 CCF50870.1 - 0.00011 21.7 0.0 0.00075 19.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CCF50870.1 - 0.0033 16.6 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 CCF50870.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.7 1 0 0 1 1 1 0 EF hand Cofilin_ADF PF00241.15 CCF50872.1 - 3.6e-44 149.6 1.6 4.1e-44 149.5 1.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HLH PF00010.21 CCF50873.1 - 5.1e-15 54.9 0.2 9.1e-15 54.1 0.2 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.7 CCF50873.1 - 0.24 10.0 1.3 0.38 9.3 0.9 1.3 1 0 0 1 1 1 0 Hamartin protein Prenylcys_lyase PF07156.9 CCF50874.1 - 5.3e-41 140.7 0.0 2.3e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 CCF50874.1 - 2.8e-09 36.8 0.0 8.1e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CCF50874.1 - 0.00022 20.4 0.0 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 CCF50874.1 - 0.003 17.3 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 CCF50874.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCF50874.1 - 0.049 13.5 0.0 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF50874.1 - 0.06 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCF50874.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CCF50874.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Na_H_Exchanger PF00999.16 CCF50875.1 - 2.8e-60 203.8 39.3 4.3e-60 203.2 27.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RVT_2 PF07727.9 CCF50876.1 - 7.8e-30 103.6 0.0 2.3e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP2C PF00481.16 CCF50878.1 - 6.5e-79 264.9 0.0 9.5e-79 264.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.27 CCF50879.1 - 1.6e-27 94.3 0.1 3.1e-08 33.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 CCF50879.1 - 0.0057 14.8 0.4 0.009 14.1 0.3 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCF50879.1 - 0.051 12.6 0.0 0.65 9.0 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Hid1 PF12722.2 CCF50880.1 - 0.97 7.0 21.4 1.1 6.8 14.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Intimin_C PF07979.6 CCF50880.1 - 4.8 7.4 11.5 0.093 12.9 2.0 2.2 1 1 1 2 2 2 0 Intimin C-type lectin domain PH_10 PF15411.1 CCF50881.1 - 2.7e-30 104.9 0.0 4.9e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 CCF50881.1 - 6.9e-06 25.7 1.5 1.7e-05 24.5 1.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCF50881.1 - 0.0016 18.1 1.0 0.0074 15.9 1.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain VWA_3 PF13768.1 CCF50881.1 - 0.0046 16.6 0.2 0.66 9.6 0.0 3.1 3 0 0 3 3 3 1 von Willebrand factor type A domain zf-C3HC4_2 PF13923.1 CCF50881.1 - 0.016 15.2 1.1 0.035 14.1 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FliH PF02108.11 CCF50881.1 - 0.028 14.3 0.4 0.45 10.3 0.3 2.4 2 0 0 2 2 2 0 Flagellar assembly protein FliH zf-C3HC4_3 PF13920.1 CCF50881.1 - 0.044 13.4 0.7 0.17 11.5 0.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF50881.1 - 0.069 13.2 0.3 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCF50881.1 - 0.11 12.1 0.4 0.26 10.9 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Chromo PF00385.19 CCF50883.1 - 4.1e-10 39.1 4.6 4.6e-08 32.6 0.9 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ASD1 PF08688.5 CCF50883.1 - 0.0018 18.0 0.1 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD1 HTH_Tnp_ISL3 PF13542.1 CCF50883.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Ribonuc_red_lgC PF02867.10 CCF50884.1 - 8.3e-216 717.7 0.0 1.1e-215 717.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCF50884.1 - 5.1e-25 87.0 0.0 1.7e-24 85.4 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCF50884.1 - 1.9e-17 63.4 1.8 1.2e-16 60.8 0.2 2.8 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 CCF50884.1 - 0.015 13.3 0.0 0.025 12.6 0.0 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Na_Ca_ex PF01699.19 CCF50885.1 - 6.8e-28 97.0 24.9 4.3e-15 55.5 6.5 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCF50885.1 - 3.5e-14 52.9 6.8 3.5e-14 52.9 4.7 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF307) DUF2367 PF10164.4 CCF50885.1 - 0.095 12.5 1.3 0.36 10.7 0.9 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Ufd2P_core PF10408.4 CCF50887.1 - 9.3e-184 612.1 0.0 1.1e-183 611.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CCF50887.1 - 1.9e-27 95.0 0.5 4.7e-27 93.7 0.4 1.7 1 0 0 1 1 1 1 U-box domain BCNT PF07572.7 CCF50888.1 - 7.3e-20 70.7 1.4 7.3e-20 70.7 0.9 2.1 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF4505 PF14956.1 CCF50891.1 - 2.7e-25 89.0 0.0 1.7e-12 47.3 0.0 2.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4505) Ribosomal_S8 PF00410.14 CCF50892.1 - 3.5e-19 68.9 0.0 5.2e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Yos1 PF08571.5 CCF50893.1 - 1.7e-29 101.7 0.8 2.1e-29 101.4 0.6 1.1 1 0 0 1 1 1 1 Yos1-like DnaJ PF00226.26 CCF50894.1 - 2.5e-26 91.2 3.0 3.5e-26 90.7 2.1 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCF50894.1 - 1.2e-13 50.7 3.1 1.4e-11 44.1 0.2 2.9 2 2 0 2 2 2 2 DnaJ C terminal domain UDG PF03167.14 CCF50896.1 - 1.4e-17 63.5 0.0 2.7e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Arrestin_N PF00339.24 CCF50897.1 - 7.6e-05 22.5 0.0 0.00022 21.0 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCF50897.1 - 0.0029 17.1 0.0 0.026 14.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Aldedh PF00171.17 CCF50898.1 - 7.8e-155 515.7 0.0 9.2e-155 515.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HpaB PF03241.8 CCF50898.1 - 0.021 13.6 0.0 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal NDUFA12 PF05071.11 CCF50899.1 - 2.7e-25 88.8 2.5 3.3e-25 88.5 1.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 MIS13 PF08202.6 CCF50900.1 - 1.6e-19 70.0 6.2 1.6e-19 70.0 4.3 2.9 2 2 0 2 2 2 1 Mis12-Mtw1 protein family YhfH PF14149.1 CCF50902.1 - 0.19 11.5 0.7 0.57 10.0 0.5 1.8 1 0 0 1 1 1 0 YhfH-like protein DUF1510 PF07423.6 CCF50902.1 - 4 6.7 9.0 0.2 10.9 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Flavokinase PF01687.12 CCF50903.1 - 1.8e-35 121.5 0.0 2.9e-35 120.8 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase Thr_synth_N PF14821.1 CCF50904.1 - 6e-27 93.4 0.0 1.5e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CCF50904.1 - 1.5e-16 60.5 0.0 2.8e-15 56.3 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme G0-G1_switch_2 PF15103.1 CCF50905.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.7 4 0 0 4 4 4 0 G0/G1 switch protein 2 CAP PF00188.21 CCF50906.1 - 1.1e-10 42.0 1.7 3.6e-10 40.4 1.2 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TMEM237 PF15383.1 CCF50906.1 - 0.084 11.9 0.8 0.16 11.0 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 XPG_I PF00867.13 CCF50907.1 - 4.2e-11 42.7 0.0 2.2e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCF50907.1 - 2.3e-06 27.7 0.0 4.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CCF50907.1 - 7.2e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Phe_tRNA-synt_N PF02912.13 CCF50907.1 - 0.06 13.0 0.7 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DUF4404 PF14357.1 CCF50907.1 - 4.7 7.7 11.4 6 7.3 2.8 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) V-ATPase_G PF03179.10 CCF50909.1 - 1.3e-35 121.8 18.0 1.8e-35 121.3 12.5 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CCF50909.1 - 0.0071 16.1 13.3 0.0071 16.1 9.2 2.4 1 1 2 3 3 3 2 ATP synthase B/B' CF(0) ATP-synt_F6 PF05511.6 CCF50909.1 - 0.019 14.8 8.9 0.062 13.2 4.6 2.5 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Colicin-DNase PF12639.2 CCF50909.1 - 0.28 11.4 5.7 0.61 10.3 3.9 1.8 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Seryl_tRNA_N PF02403.17 CCF50909.1 - 0.34 10.9 21.7 0.1 12.6 11.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3552 PF12072.3 CCF50909.1 - 0.41 9.8 27.2 0.55 9.4 18.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2362 PF10154.4 CCF50909.1 - 0.92 8.1 17.0 1.1 7.9 11.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) PAXIP1_C PF15364.1 CCF50909.1 - 1.4 8.7 13.0 2 8.3 8.9 1.3 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Prominin PF05478.6 CCF50909.1 - 2.8 5.3 12.9 3 5.2 8.9 1.0 1 0 0 1 1 1 0 Prominin ATP11 PF06644.6 CCF50909.1 - 3.1 7.2 14.9 3.8 6.9 10.3 1.2 1 0 0 1 1 1 0 ATP11 protein DUF4375 PF14300.1 CCF50909.1 - 3.4 7.6 10.0 3.7 7.5 2.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) BTV_NS2 PF04514.7 CCF50909.1 - 3.8 6.2 14.0 4.4 6.0 9.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PEP-utilisers_N PF05524.8 CCF50909.1 - 4.9 6.9 9.6 8.6 6.1 1.9 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal AIF-MLS PF14962.1 CCF50909.1 - 4.9 6.7 7.8 6.1 6.4 5.2 1.4 1 1 0 1 1 1 0 Mitochondria Localisation Sequence Symplekin_C PF12295.3 CCF50910.1 - 2.8e-61 206.6 0.4 1.2e-60 204.5 0.0 2.3 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 CCF50910.1 - 1.9e-59 200.9 1.1 4e-59 199.9 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Selenoprotein_S PF06936.6 CCF50910.1 - 0.16 11.5 3.7 0.35 10.3 2.5 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Rhabdo_ncap PF00945.13 CCF50910.1 - 2.6 6.5 6.7 0.13 10.8 0.6 1.7 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein OPT PF03169.10 CCF50911.1 - 1.1e-172 575.7 54.2 1.2e-172 575.5 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein His_Phos_2 PF00328.17 CCF50912.1 - 3.4e-40 138.4 0.0 4.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sec7 PF01369.15 CCF50913.1 - 3.9e-62 209.3 0.0 8.7e-62 208.1 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCF50913.1 - 4.4e-56 188.9 4.9 4.4e-56 188.9 3.4 3.8 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCF50913.1 - 5.4e-31 105.9 9.3 1.3e-30 104.7 0.1 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Mob1_phocein PF03637.12 CCF50914.1 - 1.1e-74 249.8 0.1 1.3e-74 249.6 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Glyco_tranf_2_3 PF13641.1 CCF50916.1 - 4.2e-30 105.2 0.0 5.9e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCF50916.1 - 2.2e-18 66.6 6.0 2.2e-18 66.6 4.2 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 CCF50916.1 - 4e-09 36.0 0.0 6.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CCF50916.1 - 2.8e-05 23.8 0.0 5.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Acyl_transf_3 PF01757.17 CCF50917.1 - 9e-15 54.3 37.6 2.4e-14 52.9 26.0 1.7 1 1 0 1 1 1 1 Acyltransferase family Glyco_hydro_16 PF00722.16 CCF50917.1 - 0.00078 18.7 0.1 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sel1 PF08238.7 CCF50918.1 - 3.2e-26 91.1 36.0 0.00036 21.0 0.9 11.0 11 1 0 11 11 11 7 Sel1 repeat TPR_7 PF13176.1 CCF50918.1 - 0.01 15.5 7.9 0.096 12.5 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.4 CCF50918.1 - 0.018 14.4 0.6 3.6 6.9 0.1 2.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_8 PF13181.1 CCF50918.1 - 0.36 10.7 0.0 0.36 10.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCF50918.1 - 0.97 9.5 0.0 0.97 9.5 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF50918.1 - 1.2 8.8 0.0 1.2 8.8 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CCF50918.1 - 1.8 8.7 9.1 0.48 10.5 0.6 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DRIM PF07539.7 CCF50919.1 - 2.3e-43 147.0 0.0 1.3e-42 144.5 0.0 2.5 2 0 0 2 2 2 1 Down-regulated in metastasis Glyco_hydro_30 PF02055.11 CCF50920.1 - 2.4e-21 75.5 0.2 4.2e-21 74.7 0.1 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AMP-binding PF00501.23 CCF50922.1 - 2.9e-86 289.4 0.0 4e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF50922.1 - 6.5e-10 39.8 0.2 2.4e-09 37.9 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DnaJ_CXXCXGXG PF00684.14 CCF50924.1 - 0.15 12.1 25.5 0.034 14.1 10.2 2.5 2 0 0 2 2 2 0 DnaJ central domain Kri1 PF05178.7 CCF50925.1 - 1.1e-29 102.6 8.8 1.1e-29 102.6 6.1 5.3 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.2 CCF50925.1 - 3.2e-25 87.8 1.6 3.2e-25 87.8 1.1 3.9 3 1 0 3 3 3 1 KRI1-like family C-terminal Ribosomal_L25p PF01386.14 CCF50925.1 - 0.015 15.3 0.1 3 8.0 0.0 3.2 2 0 0 2 2 2 0 Ribosomal L25p family Alpha_GJ PF03229.8 CCF50925.1 - 2.6 8.4 6.8 2.9 8.2 0.2 3.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J p450 PF00067.17 CCF50926.1 - 3e-21 75.4 0.0 5.7e-21 74.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 GTP1_OBG PF01018.17 CCF50927.1 - 1.9e-39 134.8 1.1 1.6e-27 96.0 0.8 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCF50927.1 - 3.1e-18 65.8 0.0 6.4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RRM_1 PF00076.17 CCF50927.1 - 3e-05 23.5 0.0 0.00067 19.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 CCF50927.1 - 7.5e-05 22.2 0.1 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCF50927.1 - 0.00012 21.4 0.2 0.00043 19.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CCF50927.1 - 0.0094 15.1 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ArgK PF03308.11 CCF50927.1 - 0.019 13.7 0.9 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 CCF50927.1 - 0.02 14.1 0.0 0.94 8.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 CCF50927.1 - 0.035 13.5 0.2 0.99 8.8 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CCF50927.1 - 0.043 14.1 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Cellulase PF00150.13 CCF50928.1 - 3.1e-13 49.5 2.1 3.4e-13 49.4 0.1 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RCC1 PF00415.13 CCF50929.1 - 1.6e-39 133.8 3.0 3.8e-10 39.8 0.0 6.7 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCF50929.1 - 3.3e-23 80.7 16.9 1.6e-07 30.7 0.2 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 CCF50929.1 - 7.4e-10 38.3 5.6 1.6e-09 37.2 3.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-UDP PF14569.1 CCF50929.1 - 0.00012 21.7 4.3 0.00018 21.2 1.8 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_1 PF14446.1 CCF50929.1 - 0.014 15.0 0.7 0.014 15.0 0.5 2.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 CCF50929.1 - 0.02 14.8 2.5 0.053 13.5 1.7 1.7 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 CCF50929.1 - 0.22 11.2 2.8 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CCF50929.1 - 0.57 9.5 3.8 0.23 10.8 0.8 1.8 2 0 0 2 2 2 0 PHD-finger OrfB_Zn_ribbon PF07282.6 CCF50929.1 - 1.8 8.2 3.8 5.9 6.6 0.5 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Glyco_tranf_2_3 PF13641.1 CCF50930.1 - 3.3e-07 30.3 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCF50930.1 - 4.2e-07 29.8 2.4 7.4e-07 29.0 1.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CCF50930.1 - 8.8e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCF50930.1 - 0.01 15.1 0.1 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 TauD PF02668.11 CCF50932.1 - 1.2e-29 103.7 0.1 1.5e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family BofC_C PF08955.5 CCF50932.1 - 0.041 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 BofC C-terminal domain eIF2A PF08662.6 CCF50933.1 - 1.4e-82 276.1 0.5 2.2e-81 272.2 0.0 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCF50933.1 - 0.047 13.6 3.0 4.4 7.3 0.0 4.7 6 0 0 6 6 6 0 WD domain, G-beta repeat Proteasome_A_N PF10584.4 CCF50933.1 - 0.92 8.8 3.1 32 3.9 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Dynein_heavy PF03028.10 CCF50934.1 - 2.5e-160 534.8 0.0 5.6e-160 533.7 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CCF50934.1 - 2.6e-47 161.2 6.2 2.6e-47 161.2 4.3 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CCF50934.1 - 8.4e-45 152.3 0.0 1.8e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 Sipho_Gp157 PF05565.6 CCF50934.1 - 0.0045 16.5 0.9 0.0045 16.5 0.6 3.7 4 0 0 4 4 4 2 Siphovirus Gp157 Atg14 PF10186.4 CCF50934.1 - 9.1 5.1 22.5 1.3 7.9 0.7 3.0 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Gal-bind_lectin PF00337.17 CCF50935.1 - 0.039 13.2 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Galactoside-binding lectin Prenyltrans PF00432.16 CCF50936.1 - 3.7e-36 122.3 12.4 2.2e-13 49.5 0.3 6.6 5 2 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCF50936.1 - 7.4e-22 77.8 0.0 7e-13 48.9 0.0 3.7 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCF50936.1 - 1e-08 35.1 0.0 0.00043 20.2 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like SQS_PSY PF00494.14 CCF50937.1 - 3.5e-35 121.5 0.0 6.5e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase Methyltransf_31 PF13847.1 CCF50938.1 - 3.3e-12 46.2 0.1 1.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CCF50938.1 - 5e-12 45.5 0.0 8.4e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCF50938.1 - 1.5e-10 41.6 0.0 3.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CCF50938.1 - 1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CCF50938.1 - 6.5e-08 32.6 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF50938.1 - 1.1e-07 31.3 0.1 2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CCF50938.1 - 1.6e-07 31.7 0.0 2.1e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF50938.1 - 2.6e-06 27.7 0.0 8e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF50938.1 - 1.7e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCF50938.1 - 6.2e-05 22.2 0.0 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CCF50938.1 - 0.00015 22.2 0.0 0.00048 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CCF50938.1 - 0.00022 20.7 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_24 PF13578.1 CCF50938.1 - 0.00022 22.0 0.1 0.0016 19.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 CCF50938.1 - 0.00084 18.9 0.0 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 CCF50938.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CCF50938.1 - 0.0035 16.7 0.2 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 CCF50938.1 - 0.007 15.1 0.0 0.015 13.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 CCF50938.1 - 0.023 14.6 0.0 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Met_10 PF02475.11 CCF50938.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Peptidase_M28 PF04389.12 CCF50939.1 - 3e-28 98.7 0.0 5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 MSP1_C PF07462.6 CCF50939.1 - 1.1 7.5 3.9 1.9 6.7 2.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus APG9 PF04109.11 CCF50940.1 - 2e-162 540.2 0.3 2.5e-162 540.0 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF3816 PF12822.2 CCF50940.1 - 0.083 12.7 0.1 0.083 12.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) SNF5 PF04855.7 CCF50941.1 - 7.7e-82 274.4 1.7 7.7e-82 274.4 1.2 3.2 3 0 0 3 3 3 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 CCF50941.1 - 0.00028 20.1 1.7 0.00059 19.1 1.1 1.6 1 0 0 1 1 1 1 GATA zinc finger CPSase_L_D2 PF02786.12 CCF50942.1 - 7.1e-76 254.1 0.0 1.2e-75 253.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCF50942.1 - 3.1e-41 139.9 0.0 1.5e-40 137.7 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCF50942.1 - 2.9e-32 110.8 0.0 9.1e-32 109.2 0.0 1.9 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCF50942.1 - 8.8e-15 54.9 0.1 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCF50942.1 - 5.2e-13 48.4 0.0 8.4e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCF50942.1 - 2.5e-10 40.0 0.0 5.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 CCF50942.1 - 3.9e-10 39.2 1.2 8.5e-10 38.1 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 CCF50942.1 - 2.9e-08 33.2 0.0 9.7e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCF50942.1 - 1.2e-05 24.9 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CCF50942.1 - 6.8e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCF50942.1 - 0.0001 21.8 0.0 0.00028 20.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 CCF50942.1 - 0.00079 18.9 0.0 0.0044 16.5 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 CCF50942.1 - 0.018 14.2 0.2 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF3182 PF11379.3 CCF50942.1 - 0.025 13.2 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Cro PF09048.5 CCF50942.1 - 0.044 13.4 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Cro EMP24_GP25L PF01105.19 CCF50943.1 - 1.4e-41 142.2 0.0 1.8e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF267 PF03268.9 CCF50943.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 rve PF00665.21 CCF50944.1 - 2.2e-19 69.7 0.0 3.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain ASD1 PF08688.5 CCF50944.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 CHCH PF06747.8 CCF50947.1 - 1.3e-05 24.9 3.6 1.8e-05 24.4 2.5 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 CCF50947.1 - 2.1e-05 24.5 2.9 3.3e-05 23.9 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) NDUF_B7 PF05676.8 CCF50947.1 - 0.00067 19.0 1.8 0.00093 18.5 1.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.4 CCF50947.1 - 0.037 14.0 2.8 0.051 13.6 2.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 CCF50947.1 - 0.074 12.9 1.9 0.086 12.7 0.4 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) NuA4 PF09340.5 CCF50948.1 - 9.2e-23 79.6 0.6 1.9e-22 78.6 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 AvrPphF-ORF-2 PF09143.5 CCF50949.1 - 0.064 12.9 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 AvrPphF-ORF-2 ER_lumen_recept PF00810.13 CCF50952.1 - 5.7e-57 192.3 7.2 7.9e-57 191.8 5.0 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CCF50952.1 - 0.0002 20.8 6.6 0.58 9.7 0.0 4.0 2 1 2 4 4 4 2 PQ loop repeat DUF485 PF04341.7 CCF50952.1 - 0.62 9.8 4.7 3.5 7.3 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function, DUF485 DAGK_cat PF00781.19 CCF50953.1 - 1.6e-13 50.2 0.0 3.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SMC_N PF02463.14 CCF50954.1 - 1.3e-68 230.5 0.0 2.2e-68 229.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCF50954.1 - 1.5e-29 102.3 0.1 5.7e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCF50954.1 - 3.1e-16 60.2 10.6 1.9e-09 37.9 0.1 3.2 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 CCF50954.1 - 4.6e-12 46.6 29.5 4.6e-12 46.6 20.5 6.6 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 CCF50954.1 - 0.0035 16.8 0.0 0.008 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CCF50954.1 - 0.059 12.5 15.0 0.72 8.9 0.1 5.0 3 2 1 4 4 4 0 Reovirus sigma C capsid protein FtsK_SpoIIIE PF01580.13 CCF50954.1 - 0.28 10.6 0.0 0.28 10.6 0.0 4.2 4 2 0 5 5 5 0 FtsK/SpoIIIE family DASH_Dad1 PF08649.5 CCF50954.1 - 2.4 7.9 9.3 12 5.7 0.0 4.4 5 0 0 5 5 5 0 DASH complex subunit Dad1 RRM_1 PF00076.17 CCF50955.1 - 1.2e-06 28.0 0.2 3.2e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50955.1 - 1.8e-05 24.5 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50955.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 CCF50956.1 - 2.2e-15 56.5 0.0 5.2e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.7 CCF50956.1 - 0.0067 16.2 7.0 0.11 12.2 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) DUF812 PF05667.6 CCF50956.1 - 0.012 14.1 17.6 0.036 12.5 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Laminin_II PF06009.7 CCF50956.1 - 0.22 11.2 15.2 1 9.1 0.9 2.7 2 0 0 2 2 2 0 Laminin Domain II Spt20 PF12090.3 CCF50956.1 - 0.37 10.1 3.0 0.23 10.7 0.7 1.6 2 0 0 2 2 2 0 Spt20 family Tweety PF04906.8 CCF50956.1 - 0.76 8.1 4.6 0.39 9.0 0.7 1.9 2 0 0 2 2 2 0 Tweety IncA PF04156.9 CCF50956.1 - 2.1 7.8 29.9 0.34 10.4 6.3 2.8 3 0 0 3 3 3 0 IncA protein Med9 PF07544.8 CCF50956.1 - 2.8 7.7 9.3 1 9.1 1.7 3.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 CCF50956.1 - 4.7 7.5 9.8 65 3.8 0.9 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 CCF50956.1 - 5.3 6.8 32.1 7.9 6.3 7.4 2.8 2 1 0 2 2 2 0 Tropomyosin like Phage_holin_2 PF04550.7 CCF50957.1 - 0.44 10.6 0.0 0.91 9.6 0.0 1.4 1 0 0 1 1 1 0 Phage holin family 2 BRO1 PF03097.13 CCF50958.1 - 6.2e-16 58.1 0.0 6.4e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 BRO1-like domain FliC_SP PF12613.3 CCF50958.1 - 0.32 11.2 6.0 2.3 8.4 0.6 2.8 2 0 0 2 2 2 0 Flagellin structural protein FlxA PF14282.1 CCF50959.1 - 0.0065 16.3 4.7 0.0065 16.3 3.2 10.1 4 3 5 10 10 10 5 FlxA-like protein CENP-F_leu_zip PF10473.4 CCF50959.1 - 0.0073 16.1 146.3 0.018 14.9 13.8 8.2 4 1 3 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CCF50959.1 - 0.015 14.4 61.8 0.022 13.9 12.1 5.9 1 1 4 7 7 7 0 Reovirus sigma C capsid protein IncA PF04156.9 CCF50959.1 - 0.14 11.7 152.8 0.048 13.2 7.5 9.3 4 2 4 9 9 9 0 IncA protein HAD PF12710.2 CCF50960.1 - 3.8e-18 66.3 0.0 1.8e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCF50960.1 - 2.3e-16 59.5 0.0 4.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCF50960.1 - 1.8e-13 51.3 1.8 3.5e-12 47.1 1.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF50960.1 - 2.1e-13 50.0 0.0 5.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF50960.1 - 0.0039 16.8 0.1 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCF50960.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pinin_SDK_memA PF04696.8 CCF50961.1 - 1.8e-09 37.2 2.8 1.8e-09 37.2 2.0 2.5 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region FliD_C PF07195.7 CCF50961.1 - 0.037 13.3 0.2 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus vWA-TerF-like PF10138.4 CCF50962.1 - 1.4e-08 34.8 0.0 2.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 CCF50962.1 - 0.00012 22.2 0.7 0.00033 20.8 0.5 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCF50962.1 - 0.00042 20.0 0.1 0.0043 16.7 0.1 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain YqzL PF14006.1 CCF50962.1 - 0.0032 17.6 0.1 0.0084 16.2 0.0 1.7 1 0 0 1 1 1 1 YqzL-like protein COX14 PF14880.1 CCF50962.1 - 0.09 12.4 2.9 0.26 10.9 2.0 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RIC3 PF15361.1 CCF50962.1 - 0.096 12.9 0.3 0.096 12.9 0.2 2.1 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2681 PF10883.3 CCF50962.1 - 0.83 9.9 11.5 0.052 13.7 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CDK2AP PF09806.4 CCF50962.1 - 1 9.5 10.0 2.1 8.5 6.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2967 PF11179.3 CCF50962.1 - 1.2 8.6 10.5 2.6 7.4 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF533 PF04391.7 CCF50962.1 - 4.7 6.5 14.9 0.52 9.6 4.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF533) HEAT_EZ PF13513.1 CCF50964.1 - 7.9e-27 93.0 18.8 4.1e-10 39.8 0.0 11.0 8 3 4 12 12 11 6 HEAT-like repeat HEAT PF02985.17 CCF50964.1 - 2.8e-21 73.6 17.0 0.0016 18.3 0.0 9.8 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 CCF50964.1 - 1.2e-20 73.5 1.3 1.4e-06 28.4 0.0 7.2 4 4 5 9 9 9 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CCF50964.1 - 5.3e-11 42.7 0.0 0.00016 22.0 0.1 4.0 2 2 1 3 3 3 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 CCF50964.1 - 1.4e-06 28.0 0.3 1.7e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 CCF50964.1 - 4.8e-06 26.5 1.1 0.0082 16.0 0.1 4.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCF50964.1 - 1.2e-05 24.9 3.0 11 6.0 0.0 6.8 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 CCF50964.1 - 1.6e-05 23.8 1.3 0.0085 14.8 0.0 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Ecm29 PF13001.2 CCF50964.1 - 0.001 17.6 0.0 1.5 7.2 0.0 3.9 4 0 0 4 4 4 1 Proteasome stabiliser Proteasom_PSMB PF10508.4 CCF50964.1 - 0.0018 16.6 0.0 0.0084 14.4 0.0 1.9 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd3 PF12719.2 CCF50964.1 - 0.004 16.1 0.1 0.11 11.4 0.1 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain UNC45-central PF11701.3 CCF50964.1 - 0.011 15.4 0.1 0.09 12.4 0.0 2.6 3 1 0 3 3 2 0 Myosin-binding striated muscle assembly central Homeobox PF00046.24 CCF50964.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Homeobox domain CENP-B_dimeris PF09026.5 CCF50964.1 - 0.13 12.5 7.8 0.3 11.3 5.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CCF50964.1 - 0.76 9.2 6.4 1.4 8.4 4.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CCF50964.1 - 2.1 8.7 6.8 4.8 7.5 4.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRM_6 PF14259.1 CCF50967.1 - 5.6e-38 128.7 0.2 6.9e-09 35.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF50967.1 - 1.1e-30 105.0 0.1 9.4e-08 31.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50967.1 - 2.7e-23 81.5 0.0 6.5e-05 22.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF50967.1 - 0.16 11.8 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Mito_carr PF00153.22 CCF50968.1 - 3.8e-66 218.8 4.5 2.1e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.17 CCF50969.1 - 9e-49 166.1 6.4 1.5e-48 165.3 4.4 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCF50969.1 - 2.9e-11 43.7 0.1 5.8e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cpn60_TCP1 PF00118.19 CCF50970.1 - 2e-138 462.0 1.0 2.2e-138 461.9 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PH PF00169.24 CCF50971.1 - 7.1e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 PH domain RE_EcoO109I PF14511.1 CCF50971.1 - 0.28 10.5 0.1 0.46 9.8 0.1 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I SLD3 PF08639.5 CCF50972.1 - 2.2e-10 39.8 4.6 3.2e-10 39.2 3.2 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 Glyco_hydro_31 PF01055.21 CCF50973.1 - 2.5e-133 445.1 1.4 4.5e-133 444.3 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCF50973.1 - 1.4e-19 69.7 0.0 4.1e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like TP_methylase PF00590.15 CCF50974.1 - 5.1e-18 65.5 0.1 1.4e-17 64.1 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sad1_UNC PF07738.8 CCF50975.1 - 1.6e-27 95.9 0.0 2.7e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SSP160 PF06933.6 CCF50978.1 - 5.5 4.8 11.6 6.4 4.6 8.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PSI PF01437.20 CCF50979.1 - 0.00071 19.6 0.9 0.0014 18.7 0.6 1.5 1 0 0 1 1 1 1 Plexin repeat RVT_2 PF07727.9 CCF50982.1 - 1.6e-44 151.6 0.3 1.3e-27 96.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF50983.1 - 0.0027 17.3 0.1 0.0054 16.3 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF2828 PF11443.3 CCF50983.1 - 0.0087 14.3 0.1 0.011 14.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF4219 PF13961.1 CCF50984.1 - 0.0093 15.3 0.3 1.4 8.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 CCF50984.1 - 0.035 13.8 0.4 0.099 12.4 0.1 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 CCF50985.1 - 5.6e-11 41.8 0.0 7.1e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 CCF50987.1 - 4e-16 58.6 48.0 1e-14 54.0 33.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Myb_Cef PF11831.3 CCF50988.1 - 4.6e-57 192.8 4.9 4.6e-57 192.8 3.4 3.6 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CCF50988.1 - 2e-20 72.5 6.3 3e-11 43.1 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCF50988.1 - 3.8e-16 58.9 10.0 1.9e-12 47.0 2.8 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain bZIP_1 PF00170.16 CCF50989.1 - 6.1e-06 26.0 2.0 6.1e-06 26.0 1.4 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 CCF50989.1 - 0.0097 15.7 2.8 0.023 14.5 1.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Uso1_p115_head PF04869.9 CCF50990.1 - 1.2e-53 181.9 0.0 1.3e-50 171.9 0.0 2.8 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region CorA PF01544.13 CCF50990.1 - 1.5 7.7 13.3 0.083 11.9 1.8 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pox_A_type_inc PF04508.7 CCF50990.1 - 1.9 8.5 13.8 1.3 8.9 0.6 4.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Spo12 PF05032.7 CCF50991.1 - 0.00076 19.0 3.8 0.0027 17.3 0.1 2.5 2 0 0 2 2 2 2 Spo12 family SSrecog PF03531.9 CCF50992.1 - 2.1e-75 252.8 0.0 3e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCF50992.1 - 6.2e-25 87.0 0.0 2.6e-24 85.0 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 CCF50992.1 - 2.9 5.8 6.6 5.3 4.9 4.5 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF1900 PF08954.6 CCF50993.1 - 2.5e-45 153.3 0.0 6.2e-45 152.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCF50993.1 - 1.4e-31 107.8 0.2 2.9e-31 106.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCF50993.1 - 5.4e-17 60.9 2.7 5e-06 26.1 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PspA_IM30 PF04012.7 CCF50993.1 - 0.003 16.9 4.6 0.0046 16.3 3.2 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF812 PF05667.6 CCF50993.1 - 0.0044 15.5 4.5 0.0058 15.2 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Med9 PF07544.8 CCF50993.1 - 0.02 14.5 0.5 0.047 13.4 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF904 PF06005.7 CCF50993.1 - 0.25 11.6 8.6 0.45 10.8 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TSC22 PF01166.13 CCF50993.1 - 0.35 10.8 3.7 0.82 9.6 2.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Phage_GP20 PF06810.6 CCF50993.1 - 0.45 9.9 8.3 0.8 9.1 5.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 CCF50993.1 - 0.89 9.9 5.2 1.7 9.0 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RNase_T PF00929.19 CCF50994.1 - 2.1e-21 76.8 0.0 2.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease CRAL_TRIO PF00650.15 CCF50995.1 - 6.8e-28 97.1 0.1 1.1e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCF50995.1 - 8.6e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF50995.1 - 5.1e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Mucin PF01456.12 CCF50995.1 - 0.0022 17.7 18.2 0.0046 16.7 12.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 CCF50995.1 - 0.14 10.1 19.8 0.22 9.4 13.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dicty_REP PF05086.7 CCF50995.1 - 0.5 8.0 6.0 0.66 7.6 4.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 CCF50995.1 - 4.3 7.1 17.5 8.3 6.1 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pantoate_transf PF02548.10 CCF50996.1 - 4.6e-82 275.0 0.2 4.4e-77 258.7 0.1 2.8 2 1 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCF50996.1 - 1.1e-05 24.7 0.9 7.1e-05 22.1 0.0 2.4 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Zn_clus PF00172.13 CCF50997.1 - 6.5e-06 25.9 9.6 1.2e-05 25.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 CCF50998.1 - 7.7e-40 134.3 0.0 2.5e-21 75.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF50998.1 - 3.9e-33 113.2 0.0 3.1e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF50998.1 - 9.8e-17 60.5 0.0 8.7e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.5 CCF50998.1 - 0.034 13.2 54.1 0.03 13.4 34.8 2.1 2 0 0 2 2 2 0 BUD22 MIP-T3 PF10243.4 CCF50998.1 - 0.11 10.9 36.5 0.14 10.5 25.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAP1 PF08601.5 CCF50998.1 - 0.25 10.9 32.7 0.39 10.3 22.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PLRV_ORF5 PF01690.12 CCF50998.1 - 3.2 6.7 29.2 5 6.1 20.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 CCF50998.1 - 4.7 5.5 31.9 5.9 5.2 22.1 1.1 1 0 0 1 1 1 0 Daxx Family NUDIX PF00293.23 CCF50999.1 - 1.1e-17 63.9 0.0 2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CCF50999.1 - 7.9e-09 35.7 0.1 1.8e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain 7TM_GPCR_Str PF10326.4 CCF50999.1 - 0.13 11.3 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str EMG1 PF03587.9 CCF51000.1 - 7.6e-76 253.9 0.0 1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ank_2 PF12796.2 CCF51001.1 - 2.8e-22 78.8 0.6 1.7e-09 37.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCF51001.1 - 5.8e-20 71.2 4.7 7.3e-11 42.2 0.1 5.4 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.25 CCF51001.1 - 1.3e-18 65.7 0.0 4.2e-08 32.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CCF51001.1 - 8.2e-17 59.6 0.4 2.3e-05 24.1 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CCF51001.1 - 7.4e-16 57.8 0.3 5.7e-08 32.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CCF51001.1 - 6e-06 25.8 0.1 5.4e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 KilA-N domain MoCF_biosynth PF00994.19 CCF51004.1 - 1.2e-55 186.8 0.2 1.4e-27 95.8 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 CCF51004.1 - 3.5e-32 111.0 0.2 5.5e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 CCF51004.1 - 2.8e-15 56.0 0.4 1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SH3_9 PF14604.1 CCF51005.1 - 1.4e-07 30.9 0.0 2.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCF51005.1 - 2.5e-07 29.9 0.0 4.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCF51005.1 - 2.6e-05 23.6 0.0 4.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain ACBP PF00887.14 CCF51006.1 - 1.8e-28 98.0 0.0 3.2e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Peroxin-3 PF04882.7 CCF51007.1 - 1.5e-130 435.8 0.0 2.1e-130 435.3 0.0 1.2 1 0 0 1 1 1 1 Peroxin-3 PAM2 PF07145.10 CCF51007.1 - 0.0025 17.1 0.7 0.0076 15.6 0.5 1.8 1 0 0 1 1 1 1 Ataxin-2 C-terminal region TIP49 PF06068.8 CCF51008.1 - 1.8e-180 599.9 0.2 3e-180 599.1 0.2 1.3 1 1 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCF51008.1 - 1.3e-10 41.6 0.8 2.3e-06 27.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCF51008.1 - 8.1e-09 34.8 0.6 1.6e-05 24.0 0.0 2.5 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCF51008.1 - 1.3e-05 25.3 0.5 0.069 13.2 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 CCF51008.1 - 6.5e-05 22.6 0.1 0.00045 19.9 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CCF51008.1 - 0.00014 21.9 0.0 0.0073 16.3 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCF51008.1 - 0.00047 19.9 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CCF51008.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCF51008.1 - 0.0048 16.3 0.4 0.01 15.2 0.3 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF51008.1 - 0.0061 15.6 0.5 0.013 14.6 0.4 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CCF51008.1 - 0.0062 16.0 0.1 2.6 7.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCF51008.1 - 0.0081 15.3 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCF51008.1 - 0.0098 15.3 0.1 0.027 13.8 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 CCF51008.1 - 0.054 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.10 CCF51008.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 CCF51008.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain POTRA_1 PF08478.5 CCF51009.1 - 0.091 12.8 0.0 0.33 11.0 0.0 2.0 3 0 0 3 3 3 0 POTRA domain, FtsQ-type DUF2505 PF10698.4 CCF51009.1 - 0.17 11.3 0.1 17 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) CAP160 PF07918.6 CCF51009.1 - 0.21 11.2 0.4 0.5 10.0 0.3 1.6 1 0 0 1 1 1 0 CAP160 repeat rve PF00665.21 CCF51010.1 - 6e-24 84.4 0.0 1.6e-23 83.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF51010.1 - 4e-14 52.0 0.0 9.8e-14 50.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CbiN PF02553.10 CCF51011.1 - 0.15 12.0 0.3 0.33 11.0 0.1 1.6 1 1 1 2 2 2 0 Cobalt transport protein component CbiN Ceramidase PF05875.7 CCF51012.1 - 1.9e-77 259.9 5.7 2.3e-77 259.6 3.9 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_hydro_10 PF00331.15 CCF51013.1 - 4.9e-52 176.9 0.2 5.9e-52 176.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF667 PF05018.8 CCF51014.1 - 0.1 11.8 0.4 0.16 11.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF667) TrkH PF02386.11 CCF51015.1 - 1.3e-85 287.1 15.9 5.6e-84 281.7 5.6 2.1 2 0 0 2 2 2 2 Cation transport protein RNA_polI_A34 PF08208.6 CCF51016.1 - 0.0046 16.6 19.7 0.0063 16.2 13.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 CCF51016.1 - 0.041 13.0 10.7 0.051 12.7 7.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 CCF51016.1 - 2.2 8.0 11.8 2.9 7.6 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_DNAp_acc PF04929.7 CCF51016.1 - 3 6.7 11.0 3.6 6.4 7.6 1.4 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Med19 PF10278.4 CCF51016.1 - 3.1 7.4 17.3 8.1 6.0 11.9 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TSGP1 PF07771.6 CCF51016.1 - 3.8 7.4 10.7 7.5 6.4 7.4 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 UPF0016 PF01169.14 CCF51017.1 - 1.1e-42 143.9 23.5 1e-21 76.8 4.8 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TauE PF01925.14 CCF51017.1 - 7.1e-05 22.3 10.0 0.00047 19.6 0.2 2.2 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE TerC PF03741.11 CCF51017.1 - 0.004 16.6 5.3 0.057 12.8 0.4 2.4 2 0 0 2 2 2 2 Integral membrane protein TerC family DUF4131 PF13567.1 CCF51017.1 - 5.1 6.4 7.7 4.7 6.5 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Saccharop_dh PF03435.13 CCF51018.1 - 2.7e-20 72.7 0.0 3.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 CCF51018.1 - 0.00039 20.7 0.0 0.0036 17.5 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF51018.1 - 0.002 18.1 0.1 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 CCF51018.1 - 0.0033 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 CCF51018.1 - 0.0034 16.6 0.0 0.0094 15.2 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Frataxin_Cyay PF01491.11 CCF51020.1 - 4e-37 126.3 0.1 5.3e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Unstab_antitox PF09720.5 CCF51020.1 - 0.012 15.2 0.3 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 Putative addiction module component Aminotran_1_2 PF00155.16 CCF51021.1 - 3.5e-57 194.0 0.0 4.1e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Esterase PF00756.15 CCF51022.1 - 1.7e-51 175.0 0.0 2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCF51022.1 - 2.8e-06 27.1 0.0 3.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CCF51022.1 - 0.002 17.0 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 CCF51022.1 - 0.0029 17.1 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CCF51022.1 - 0.0071 15.5 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 CCF51022.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 CCF51022.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase MIF4G PF02854.14 CCF51023.1 - 3.9e-53 179.9 1.1 6.4e-53 179.2 0.1 1.9 3 0 0 3 3 3 1 MIF4G domain eIF_4G1 PF12152.3 CCF51023.1 - 5.9e-22 77.3 0.7 4.5e-21 74.5 0.2 2.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 CCF51023.1 - 6.8e-08 32.1 0.5 1.2e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 MA3 domain DUF1435 PF07256.7 CCF51024.1 - 0.095 12.7 3.4 0.17 11.8 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1435) Hydrophobin PF01185.13 CCF51025.1 - 8.1e-14 51.8 8.7 3.4e-13 49.8 6.0 2.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF3702 PF12486.3 CCF51025.1 - 0.14 11.7 4.5 4.3 7.0 0.3 3.8 3 1 0 3 3 3 0 ImpA domain protein DUF1411 PF07199.6 CCF51025.1 - 0.25 10.7 1.8 1.8 7.9 0.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1411) HSP70 PF00012.15 CCF51027.1 - 8.2e-240 796.8 4.6 9.7e-240 796.5 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCF51027.1 - 1.5e-18 66.4 1.0 1.3e-17 63.4 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 CCF51027.1 - 0.0027 16.5 1.2 0.017 13.9 0.4 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CCF51027.1 - 0.0042 16.7 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CCF51027.1 - 0.0051 16.1 0.2 0.8 8.9 0.0 2.4 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 CCF51027.1 - 0.045 12.6 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 StbA protein Ribosomal_S2 PF00318.15 CCF51028.1 - 1.2e-46 158.6 0.0 2e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S2 ABC_membrane PF00664.18 CCF51029.1 - 9.4e-70 235.1 30.0 2.7e-41 141.8 5.7 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF51029.1 - 3e-62 208.9 0.0 1.2e-29 103.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF51029.1 - 3.9e-15 55.6 3.2 9.5e-06 24.9 0.2 4.4 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF51029.1 - 1.3e-09 38.4 0.0 0.5 10.2 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 CCF51029.1 - 1.5e-08 35.4 0.0 0.0008 20.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCF51029.1 - 2.7e-08 33.6 0.3 0.081 12.3 0.0 4.3 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 CCF51029.1 - 4.8e-08 33.2 0.3 0.086 12.9 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF51029.1 - 5.7e-07 28.9 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 CCF51029.1 - 8.1e-07 29.3 0.0 0.015 15.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF51029.1 - 2.9e-06 27.4 11.5 0.0019 18.2 0.3 4.1 3 2 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 CCF51029.1 - 1.2e-05 25.2 2.5 0.017 14.9 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 CCF51029.1 - 0.00013 21.2 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCF51029.1 - 0.00028 20.7 0.1 1.6 8.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CCF51029.1 - 0.00032 20.4 0.0 1.6 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CCF51029.1 - 0.00035 20.5 0.0 0.22 11.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCF51029.1 - 0.00041 19.7 0.1 1.6 8.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CCF51029.1 - 0.00057 19.3 2.1 1.3 8.4 0.0 3.6 4 0 0 4 4 4 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCF51029.1 - 0.00073 18.6 0.0 0.34 9.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 CCF51029.1 - 0.0011 19.2 0.2 3.1 8.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain APS_kinase PF01583.15 CCF51029.1 - 0.0013 18.3 0.0 1.2 8.7 0.0 2.8 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.1 CCF51029.1 - 0.0029 17.4 0.1 0.34 10.8 0.1 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCF51029.1 - 0.0039 17.3 0.0 5 7.3 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 CCF51029.1 - 0.0049 17.0 0.6 53 4.0 0.1 4.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCF51029.1 - 0.0055 16.3 0.2 4.3 6.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCF51029.1 - 0.0078 16.1 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CCF51029.1 - 0.01 15.2 0.0 1.6 8.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family CPT PF07931.7 CCF51029.1 - 0.011 15.3 0.1 3.4 7.2 0.0 3.5 4 0 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 CCF51029.1 - 0.012 15.2 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CCF51029.1 - 0.042 14.3 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein tRNA_lig_kinase PF08303.6 CCF51029.1 - 0.046 13.5 0.0 9.8 6.0 0.0 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain CbiA PF01656.18 CCF51029.1 - 0.051 12.9 0.0 7 6.0 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 CCF51029.1 - 0.057 12.1 0.0 7 5.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit MobB PF03205.9 CCF51029.1 - 0.074 12.7 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCF51029.1 - 0.077 11.8 0.1 2.4 6.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain UBN2 PF14223.1 CCF51030.1 - 0.00031 20.5 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 CCF51030.1 - 0.02 14.4 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1600 PF07667.6 CCF51030.1 - 0.022 14.8 0.1 0.027 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) UBN2_3 PF14244.1 CCF51030.1 - 0.028 13.9 1.0 0.12 11.9 0.1 2.0 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Cyclin PF08613.6 CCF51031.1 - 1.3e-08 35.3 0.1 1.3e-08 35.3 0.1 2.2 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CCF51031.1 - 1.9e-08 33.9 0.0 3.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain adh_short PF00106.20 CCF51032.1 - 2.5e-22 79.5 0.1 3.4e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF51032.1 - 1.5e-09 37.9 0.1 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF51032.1 - 1.5e-06 27.9 0.1 2.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCF51032.1 - 0.00021 21.3 0.1 0.00036 20.5 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCF51032.1 - 0.0031 16.4 0.1 0.0044 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein tRNA-synt_2 PF00152.15 CCF51033.1 - 2.8e-71 240.0 0.0 3.7e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCF51033.1 - 1.4e-11 44.0 0.0 3.2e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HEAT_2 PF13646.1 CCF51034.1 - 1.4e-36 124.5 42.7 1.7e-09 37.8 0.0 15.6 10 3 4 15 15 15 10 HEAT repeats DUF3554 PF12074.3 CCF51034.1 - 1.6e-32 113.2 10.0 1.7e-30 106.6 6.5 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT PF02985.17 CCF51034.1 - 4.7e-32 107.1 27.6 0.097 12.8 0.0 20.6 22 0 0 22 22 20 9 HEAT repeat HEAT_EZ PF13513.1 CCF51034.1 - 2.7e-23 81.8 47.5 0.0001 22.6 0.0 19.5 14 4 2 17 17 16 7 HEAT-like repeat CLASP_N PF12348.3 CCF51034.1 - 4.9e-17 62.0 0.4 6e-06 25.7 0.0 7.0 4 1 2 6 6 6 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCF51034.1 - 5.3e-10 39.5 0.0 1.2 9.5 0.0 9.1 9 3 2 11 11 10 1 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 CCF51034.1 - 0.0011 18.8 2.1 1.1 9.2 0.1 4.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RIX1 PF08167.7 CCF51034.1 - 0.0091 15.6 2.4 3.4 7.3 0.0 5.3 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Arm PF00514.18 CCF51034.1 - 0.0097 15.7 14.4 32 4.5 0.1 9.8 10 1 1 11 11 11 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.1 CCF51034.1 - 0.013 15.4 0.1 15 5.5 0.0 4.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Membr_traf_MHD PF10540.4 CCF51034.1 - 0.015 15.0 0.0 0.057 13.2 0.0 2.0 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain DUF3437 PF11919.3 CCF51034.1 - 0.02 14.5 0.1 3.5 7.4 0.0 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Pox_RNA_Pol_19 PF05320.7 CCF51034.1 - 0.55 9.9 4.9 1.4 8.6 3.4 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mito_carr PF00153.22 CCF51035.1 - 1.3e-47 159.4 0.1 5.7e-15 54.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CCF51035.1 - 0.018 14.9 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Anoctamin PF04547.7 CCF51036.1 - 2.3e-108 362.7 0.3 2.9e-108 362.4 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel LSM PF01423.17 CCF51037.1 - 5.1e-15 54.7 0.1 9.5e-15 53.9 0.0 1.5 2 0 0 2 2 2 1 LSM domain zf-CCCH_2 PF14608.1 CCF51038.1 - 1.1e-11 44.2 29.6 0.0016 18.3 0.4 4.3 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type TraT PF05818.7 CCF51038.1 - 0.0053 16.2 0.1 0.009 15.4 0.1 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Nab2 PF11517.3 CCF51038.1 - 0.0084 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) KxDL PF10241.4 CCF51040.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2244 PF10003.4 CCF51040.1 - 0.0088 15.4 1.1 0.015 14.6 0.7 1.3 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) EF-hand_6 PF13405.1 CCF51041.1 - 6.8e-11 41.1 0.3 0.00016 21.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CCF51041.1 - 1.5e-10 41.0 0.9 0.00063 19.8 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCF51041.1 - 4.6e-10 38.0 2.4 3.1e-05 22.9 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CCF51041.1 - 2.1e-06 26.7 4.7 0.0014 17.8 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CCF51041.1 - 9e-06 25.5 0.0 0.0064 16.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CCF51041.1 - 0.00034 20.1 1.6 0.15 11.6 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair NAPRTase PF04095.11 CCF51043.1 - 1.7e-51 174.8 0.0 2.3e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Glyco_transf_90 PF05686.7 CCF51044.1 - 1e-27 96.8 2.7 4.2e-24 84.9 0.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 Transket_pyr PF02779.19 CCF51045.1 - 1.4e-62 210.3 0.0 2.2e-62 209.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCF51045.1 - 1.7e-61 207.5 0.0 2.3e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Y_phosphatase PF00102.22 CCF51047.1 - 9e-53 179.0 0.0 4.3e-27 94.9 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCF51047.1 - 0.00071 19.8 0.0 0.046 14.0 0.0 3.5 4 0 0 4 4 4 1 Rhodanese-like domain PTPlike_phytase PF14566.1 CCF51047.1 - 0.037 14.0 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCF51047.1 - 0.063 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CCF51047.1 - 0.13 11.8 0.3 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cwf_Cwc_15 PF04889.7 CCF51048.1 - 1.6e-57 195.0 17.7 2.6e-57 194.3 12.3 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Parvo_coat PF00740.13 CCF51048.1 - 0.24 10.3 3.2 0.29 10.0 2.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SART-1 PF03343.8 CCF51048.1 - 0.27 9.5 22.4 0.37 9.0 15.5 1.1 1 0 0 1 1 1 0 SART-1 family Nop14 PF04147.7 CCF51048.1 - 0.76 7.6 21.6 0.98 7.2 15.0 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.6 CCF51048.1 - 8.9 6.1 24.7 14 5.5 17.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FKBP_C PF00254.23 CCF51049.1 - 7.3e-36 122.0 0.0 9.4e-36 121.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.20 CCF51050.1 - 3.2e-67 226.4 0.0 3.8e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51050.1 - 4.8e-36 124.1 0.0 6.6e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51050.1 - 0.00072 18.5 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCF51050.1 - 0.02 13.9 0.0 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCF51050.1 - 0.064 12.5 0.1 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 CCF51050.1 - 0.073 12.7 0.0 0.24 11.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0220 PF05255.6 CCF51051.1 - 9.2e-56 187.6 0.0 1.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PrgI PF12666.2 CCF51051.1 - 0.24 11.5 1.7 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 PrgI family protein ApbA PF02558.11 CCF51052.1 - 4.6e-28 97.5 0.2 7.5e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCF51052.1 - 1.6e-25 89.5 0.0 3.1e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 CCF51052.1 - 0.0057 15.6 2.0 0.036 12.9 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase ThiF PF00899.16 CCF51052.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 CCF51052.1 - 0.09 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 CCF51052.1 - 0.097 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase polyprenyl_synt PF00348.12 CCF51053.1 - 8.5e-44 149.3 0.0 7.2e-22 77.4 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase RNA_pol_Rpb8 PF03870.10 CCF51054.1 - 1.5e-38 132.0 1.3 1.2e-36 125.9 0.9 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 E1-E2_ATPase PF00122.15 CCF51055.1 - 1.2e-74 250.2 2.2 3e-74 248.9 1.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF51055.1 - 6.6e-32 110.5 0.1 1.8e-31 109.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF51055.1 - 5.8e-31 108.5 0.0 3.2e-30 106.1 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF51055.1 - 1.6e-16 61.0 0.5 5.8e-16 59.2 0.2 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF51055.1 - 4.8e-12 45.1 0.0 1.1e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCF51055.1 - 2.8e-11 43.1 0.0 5.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF51055.1 - 2.6e-05 23.9 0.8 0.0013 18.3 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4589 PF15252.1 CCF51055.1 - 0.068 12.9 11.2 0.033 14.0 1.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4589) Med17 PF10156.4 CCF51056.1 - 3.2e-05 22.3 0.3 3.2e-05 22.3 0.2 3.0 2 1 0 2 2 2 1 Subunit 17 of Mediator complex TRAP_alpha PF03896.11 CCF51056.1 - 0.0017 17.4 4.0 0.0017 17.4 2.8 1.8 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.1 CCF51056.1 - 0.023 14.9 1.0 0.023 14.9 0.7 2.0 2 1 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RRN3 PF05327.6 CCF51056.1 - 0.052 11.6 1.2 0.1 10.6 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.17 CCF51056.1 - 0.19 10.7 0.3 0.33 9.9 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.10 CCF51056.1 - 0.21 10.2 1.7 0.33 9.6 1.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) GAGA_bind PF06217.7 CCF51056.1 - 0.44 10.4 5.6 0.9 9.4 3.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 CCF51056.1 - 0.56 9.3 15.9 0.98 8.5 11.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) NARP1 PF12569.3 CCF51056.1 - 0.57 8.8 14.2 0.96 8.1 9.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 CCF51056.1 - 0.64 7.6 7.2 1 7.0 5.0 1.2 1 0 0 1 1 1 0 Ycf1 Fmp27 PF10344.4 CCF51056.1 - 1.2 6.7 5.1 1.7 6.1 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Tim54 PF11711.3 CCF51056.1 - 4.6 5.7 12.2 12 4.3 8.5 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1682 PF07946.9 CCF51056.1 - 5 5.8 22.4 9 5.0 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CDC45 PF02724.9 CCF51056.1 - 5.3 4.9 12.9 0.068 11.1 3.7 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF3402 PF11882.3 CCF51056.1 - 9.2 5.1 10.2 30 3.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Lectin_leg-like PF03388.8 CCF51057.1 - 1.2e-61 207.8 0.1 2e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 CCF51057.1 - 1.8e-05 24.2 0.0 0.0001 21.7 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain FAD_binding_4 PF01565.18 CCF51058.1 - 2.2e-11 43.3 0.9 0.00018 20.9 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 CCF51058.1 - 2.1e-07 30.7 0.0 4.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Bromodomain PF00439.20 CCF51059.1 - 7.1e-23 80.3 0.1 1.4e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CCF51059.1 - 6.9e-06 25.7 0.1 9.4e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 Bromodomain associated adh_short PF00106.20 CCF51060.1 - 4e-10 39.8 0.6 3.7e-07 30.1 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCF51060.1 - 7e-09 35.7 0.0 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF51060.1 - 0.00028 20.6 0.5 0.00088 18.9 0.1 1.9 2 0 0 2 2 2 1 KR domain Pyridox_oxidase PF01243.15 CCF51061.1 - 6.1e-11 42.1 0.0 7e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GIT_SHD PF08518.6 CCF51062.1 - 6.9e-27 92.4 6.0 2.5e-15 55.4 0.7 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT FlxA PF14282.1 CCF51062.1 - 0.06 13.3 29.5 0.041 13.8 10.6 4.4 3 0 0 3 3 3 0 FlxA-like protein V_ATPase_I PF01496.14 CCF51062.1 - 0.23 9.2 7.3 0.53 8.0 5.0 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 CCF51062.1 - 0.46 10.0 23.7 1.8 8.0 7.5 3.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 CCF51062.1 - 1.8 8.8 14.4 0.13 12.5 0.8 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein zf-C2H2 PF00096.21 CCF51063.1 - 2.7e-05 24.2 3.6 0.015 15.5 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Alpha-amylase_C PF02806.13 CCF51064.1 - 5.6e-24 84.0 0.1 1.4e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CCF51064.1 - 4.7e-17 62.3 0.0 4.3e-14 52.6 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CCF51064.1 - 1.2e-15 57.3 0.0 4.5e-15 55.4 0.0 2.0 1 1 1 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3180 PF11377.3 CCF51065.1 - 0.013 15.3 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF543 PF04418.7 CCF51065.1 - 0.078 12.9 1.1 0.32 10.9 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF543) PBP1_TM PF14812.1 CCF51066.1 - 3.2 8.1 9.3 0.63 10.3 0.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RVT_2 PF07727.9 CCF51067.1 - 1.8e-13 50.0 0.0 2.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) G-patch PF01585.18 CCF51068.1 - 2.5e-08 33.5 0.9 7.2e-08 32.0 0.6 1.9 1 0 0 1 1 1 1 G-patch domain SR-25 PF10500.4 CCF51068.1 - 0.0002 20.9 22.7 0.0002 20.9 15.7 3.2 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein CDC27 PF09507.5 CCF51068.1 - 0.00091 18.5 44.6 0.007 15.6 13.5 2.1 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 SprA-related PF12118.3 CCF51068.1 - 0.0024 17.2 30.8 0.11 11.7 8.5 2.1 2 0 0 2 2 2 2 SprA-related family Adaptin_binding PF10199.4 CCF51068.1 - 0.004 17.4 22.3 0.22 11.7 5.1 2.5 2 0 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 G-patch_2 PF12656.2 CCF51068.1 - 0.011 15.6 0.9 0.011 15.6 0.6 4.5 3 2 0 3 3 1 0 DExH-box splicing factor binding site RR_TM4-6 PF06459.7 CCF51068.1 - 0.011 15.6 33.5 0.13 12.1 8.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Daxx PF03344.10 CCF51068.1 - 0.02 13.3 27.4 0.0082 14.6 5.3 2.1 2 0 0 2 2 2 0 Daxx Family TFIIF_alpha PF05793.7 CCF51068.1 - 0.034 12.5 45.0 0.051 11.9 12.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SART-1 PF03343.8 CCF51068.1 - 0.034 12.5 51.6 0.02 13.2 14.0 2.1 2 0 0 2 2 2 0 SART-1 family DUF3807 PF12720.2 CCF51068.1 - 0.11 12.6 42.1 0.72 9.9 10.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SRP-alpha_N PF04086.8 CCF51068.1 - 0.14 11.4 42.9 0.28 10.5 12.6 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF966 PF06136.8 CCF51068.1 - 0.16 11.3 31.7 0.21 10.9 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Vfa1 PF08432.5 CCF51068.1 - 0.33 10.9 54.5 2.1 8.3 16.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 CCF51068.1 - 0.37 8.7 37.5 0.68 7.8 12.1 2.1 2 0 0 2 2 2 0 CDC45-like protein YL1 PF05764.8 CCF51068.1 - 0.46 10.0 52.0 0.73 9.3 16.3 2.2 2 0 0 2 2 2 0 YL1 nuclear protein DUF2052 PF09747.4 CCF51068.1 - 0.88 9.4 25.4 2.8 7.8 6.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Na_trans_assoc PF06512.8 CCF51068.1 - 0.89 9.4 25.2 2.4 8.0 7.3 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated U79_P34 PF03064.11 CCF51068.1 - 1.1 8.7 38.4 1.1 8.7 12.1 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 PLRV_ORF5 PF01690.12 CCF51068.1 - 1.2 8.1 28.3 1.1 8.3 7.0 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein DUF572 PF04502.8 CCF51068.1 - 1.3 8.1 40.6 1.4 8.0 9.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4614 PF15391.1 CCF51068.1 - 1.6 8.4 30.4 1.1 9.0 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF2201_N PF13203.1 CCF51068.1 - 1.8 7.6 36.9 0.26 10.4 9.5 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF1510 PF07423.6 CCF51068.1 - 2.5 7.3 55.3 0.46 9.8 13.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 CCF51068.1 - 5.7 6.6 33.2 7.5 6.2 7.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) WD40 PF00400.27 CCF51069.1 - 1.4e-15 56.4 18.8 5.4e-07 29.2 0.1 6.2 5 1 0 5 5 5 4 WD domain, G-beta repeat RWD PF05773.17 CCF51069.1 - 0.0011 18.7 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 RWD domain G-alpha PF00503.15 CCF51071.1 - 6.9e-126 420.0 0.8 8.5e-126 419.7 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCF51071.1 - 1.1e-15 57.2 0.1 4.9e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF51071.1 - 5.5e-05 22.4 0.1 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF51071.1 - 0.0011 19.3 0.0 0.61 10.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CCF51071.1 - 0.039 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_A_bac PF01000.21 CCF51071.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/RpoA insert domain Mito_carr PF00153.22 CCF51073.1 - 1.9e-55 184.5 6.0 6.1e-20 70.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RhoGEF PF00621.15 CCF51074.1 - 1.9e-34 119.1 0.0 9.3e-30 103.8 0.0 2.9 3 0 0 3 3 3 2 RhoGEF domain BAR PF03114.13 CCF51074.1 - 3e-09 36.7 0.4 5.8e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 BAR domain Sugar_tr PF00083.19 CCF51075.1 - 7e-104 347.9 23.0 8e-104 347.7 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF51075.1 - 7.2e-29 100.5 33.0 1.9e-27 95.9 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCF51075.1 - 1.1e-06 27.1 2.4 1.1e-06 27.1 1.6 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ADH_N PF08240.7 CCF51076.1 - 2.2e-24 85.3 1.2 4e-24 84.4 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF51076.1 - 3.5e-17 62.1 0.0 6.9e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCF51076.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 CCF51076.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GFO_IDH_MocA PF01408.17 CCF51076.1 - 0.01 16.3 0.0 0.34 11.4 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ADH_zinc_N_2 PF13602.1 CCF51076.1 - 0.013 16.3 0.0 0.039 14.8 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MTS PF05175.9 CCF51076.1 - 0.055 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PDZ_2 PF13180.1 CCF51076.1 - 0.059 13.2 0.2 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 PDZ domain XdhC_C PF13478.1 CCF51076.1 - 0.083 13.1 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain PDZ PF00595.19 CCF51076.1 - 0.094 12.9 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Far-17a_AIG1 PF04750.9 CCF51077.1 - 1.4e-51 174.5 1.0 1.6e-51 174.3 0.7 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Voltage_CLC PF00654.15 CCF51077.1 - 0.00098 18.2 0.1 0.00098 18.2 0.1 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel zf-CCHC_6 PF15288.1 CCF51078.1 - 0.096 12.3 1.9 0.25 11.0 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CCF51078.1 - 0.84 9.6 4.0 1.7 8.7 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 CCF51079.1 - 1.8e-53 181.0 1.5 1.2e-44 152.1 0.2 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfatase PF00884.18 CCF51080.1 - 5.3e-55 186.7 0.0 6.8e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 CCF51080.1 - 7.7e-23 80.0 0.7 1.8e-22 78.9 0.5 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 CCF51080.1 - 1.4e-08 34.4 0.0 0.0002 20.8 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 CCF51080.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 CCF51080.1 - 0.0049 15.3 0.0 0.0074 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) BAF1_ABF1 PF04684.8 CCF51080.1 - 6.1 5.5 9.4 8.7 5.0 6.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TatD_DNase PF01026.16 CCF51081.1 - 2.6e-32 112.0 0.0 3.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Herpes_UL51 PF04540.8 CCF51081.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL51 protein RRM_1 PF00076.17 CCF51082.1 - 3.2e-13 49.1 0.0 3.5e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51082.1 - 2.1e-10 40.4 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51082.1 - 4.7e-06 26.3 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 CCF51082.1 - 8.6 6.6 8.1 4 7.7 0.3 3.1 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 CCF51083.1 - 1.2e-66 224.5 0.0 1.7e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51083.1 - 1.2e-28 99.9 0.0 1.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCF51083.1 - 3.8e-11 43.3 0.2 3.8e-11 43.3 0.1 4.4 4 2 1 5 5 5 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCF51083.1 - 3.8e-08 32.6 0.0 1.9e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CCF51083.1 - 4.2e-05 23.2 0.0 0.00021 21.0 0.0 2.1 1 1 0 1 1 1 1 C2 domain APH PF01636.18 CCF51083.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FlaG PF03646.10 CCF51083.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.1 2 1 0 2 2 2 0 FlaG protein SGS PF05002.10 CCF51085.1 - 7.8e-29 99.2 2.3 1.4e-28 98.4 1.6 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CCF51085.1 - 1.3e-15 57.6 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 CS domain TT_ORF2 PF02957.10 CCF51085.1 - 0.02 15.5 0.6 0.037 14.7 0.4 1.4 1 0 0 1 1 1 0 TT viral ORF2 Alg6_Alg8 PF03155.10 CCF51086.1 - 4e-119 398.5 22.9 4.4e-117 391.7 12.5 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family PUF PF00806.14 CCF51087.1 - 6.1e-64 208.0 5.3 3.1e-08 32.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 CCF51087.1 - 0.011 15.9 3.1 1.5 9.0 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function DUF260 Phosducin PF02114.11 CCF51089.1 - 3.1e-13 49.0 0.1 6.1e-09 34.9 0.0 2.4 2 1 0 2 2 2 2 Phosducin Ribosomal_60s PF00428.14 CCF51089.1 - 0.08 13.3 1.0 0.22 11.9 0.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Thioredoxin PF00085.15 CCF51089.1 - 0.1 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin GOLD_2 PF13897.1 CCF51089.1 - 0.15 12.2 5.4 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking GST_N_3 PF13417.1 CCF51090.1 - 2.3e-09 37.3 0.1 4e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF51090.1 - 4.8e-06 26.4 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCF51090.1 - 0.00013 22.3 0.0 0.00017 21.9 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCF51090.1 - 0.00026 20.8 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF51090.1 - 0.00032 20.6 0.0 0.00072 19.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCF51090.1 - 0.0072 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Metallophos PF00149.23 CCF51091.1 - 1.6e-11 44.0 0.8 3.5e-11 42.8 0.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Telomere_Sde2 PF13019.1 CCF51092.1 - 1.7e-40 138.3 0.1 1.7e-40 138.3 0.1 2.0 3 0 0 3 3 3 1 Telomere stability and silencing GTSE1_N PF15259.1 CCF51092.1 - 0.051 13.5 0.4 0.051 13.5 0.2 1.9 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Lactamase_B_2 PF12706.2 CCF51093.1 - 2.3e-06 27.2 0.1 5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 CCF51093.1 - 0.022 14.7 0.0 0.32 11.0 0.0 2.7 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase zf-RING_2 PF13639.1 CCF51094.1 - 1.5e-07 31.1 5.9 1.5e-07 31.1 4.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCF51094.1 - 1.5e-06 28.1 1.3 3.7e-06 26.9 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCF51094.1 - 0.0036 17.2 3.1 0.0097 15.8 2.1 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CCF51094.1 - 0.0043 16.8 1.6 0.0043 16.8 1.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 CCF51094.1 - 0.016 14.9 0.8 0.031 14.0 0.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 CCF51094.1 - 0.036 13.7 7.6 0.084 12.5 5.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CCF51094.1 - 0.042 13.8 8.7 0.026 14.5 3.7 2.3 2 0 0 2 2 2 0 RING-variant domain Sporozoite_P67 PF05642.6 CCF51094.1 - 0.42 8.4 6.0 0.72 7.6 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING_4 PF14570.1 CCF51094.1 - 2.7 7.6 4.9 5.2 6.7 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2457 PF10446.4 CCF51094.1 - 3.8 6.1 23.5 0.024 13.4 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 CCF51094.1 - 4.6 6.7 13.1 11 5.5 9.1 1.6 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCF51094.1 - 5 6.2 13.5 20 4.3 9.5 1.8 2 0 0 2 2 2 0 NOA36 protein zf-RING-like PF08746.6 CCF51094.1 - 5.3 7.1 4.7 12 6.0 3.2 1.6 1 0 0 1 1 1 0 RING-like domain TFIIS_M PF07500.9 CCF51095.1 - 2e-19 69.7 7.2 2e-19 69.7 5.0 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 CCF51095.1 - 7.8e-16 58.6 0.0 3.1e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 CCF51095.1 - 2.5e-12 46.2 9.5 4.3e-12 45.5 6.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF51095.1 - 0.094 12.0 3.0 0.17 11.2 2.1 1.4 1 0 0 1 1 1 0 PHD-finger Ndc1_Nup PF09531.5 CCF51095.1 - 6.9 4.9 8.3 18 3.5 5.8 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Porin_3 PF01459.17 CCF51096.1 - 7.9e-76 254.9 2.5 9.2e-76 254.7 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin Fcf1 PF04900.7 CCF51097.1 - 2.3e-39 133.5 0.9 5.3e-39 132.3 0.3 1.7 2 0 0 2 2 2 1 Fcf1 CoatB PF10389.4 CCF51098.1 - 0.0019 18.0 0.2 0.0048 16.7 0.1 1.6 1 0 0 1 1 1 1 Bacteriophage coat protein B Peptidase_M22 PF00814.20 CCF51099.1 - 1.5e-74 250.8 0.1 1.9e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Exo_endo_phos PF03372.18 CCF51100.1 - 2e-14 54.1 0.2 3.4e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCF51100.1 - 3.7e-10 39.4 0.0 8.2e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CCF51100.1 - 1.8e-06 27.7 5.9 2.8e-05 23.9 4.1 2.5 1 1 0 1 1 1 1 GRF zinc finger SCA7 PF08313.7 CCF51101.1 - 2.7e-30 103.7 0.4 5.6e-30 102.7 0.3 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain RNase_H2-Ydr279 PF09468.5 CCF51101.1 - 1.9 7.6 7.5 0.24 10.5 0.6 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DASH_Dad2 PF08654.5 CCF51102.1 - 1.1e-29 102.4 0.0 1.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 ATP-synt_ab PF00006.20 CCF51103.1 - 2.7e-110 366.9 0.0 3.8e-110 366.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCF51103.1 - 1.2e-20 74.0 0.4 2.7e-20 72.9 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCF51103.1 - 2.3e-14 53.3 3.3 6.2e-14 51.9 2.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 CCF51103.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCF51104.1 - 6.1e-42 142.9 0.0 2e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF51104.1 - 7.7e-06 26.0 0.0 0.00056 20.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCF51104.1 - 1.1e-05 25.1 0.1 5.7e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF51104.1 - 9.6e-05 22.4 0.0 0.00023 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CCF51104.1 - 0.00017 21.5 0.1 0.00063 19.6 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCF51104.1 - 0.00099 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCF51104.1 - 0.0021 18.8 0.1 0.005 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF51104.1 - 0.0033 17.1 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCF51104.1 - 0.004 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CCF51104.1 - 0.012 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CCF51104.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCF51104.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCF51104.1 - 0.019 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCF51104.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCF51104.1 - 0.023 14.4 0.1 6.5 6.3 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 CCF51104.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCF51104.1 - 0.035 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CCF51104.1 - 0.043 14.0 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 CCF51104.1 - 0.05 12.3 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 CCF51104.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CCF51104.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCF51104.1 - 0.06 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCF51104.1 - 0.092 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCF51104.1 - 0.13 11.6 0.4 0.66 9.3 0.0 2.0 1 1 0 2 2 2 0 AAA domain DUF4187 PF13821.1 CCF51105.1 - 7.6e-17 60.6 4.8 7.6e-17 60.6 3.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 CCF51105.1 - 1.2e-05 24.9 0.2 3.1e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 G-patch domain CDP-OH_P_transf PF01066.16 CCF51106.1 - 1.6e-19 70.0 5.3 3.6e-19 68.9 3.7 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Adeno_E3_CR1 PF02440.10 CCF51106.1 - 0.085 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR1 ORC3_N PF07034.6 CCF51107.1 - 4.7e-12 45.5 0.0 1.5e-05 24.1 0.0 3.4 3 1 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus DUF2205 PF10224.4 CCF51109.1 - 5.1e-14 51.5 0.3 6.6e-14 51.2 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 CCF51109.1 - 0.027 14.8 0.6 0.035 14.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Latarcin PF10279.4 CCF51109.1 - 0.044 13.9 0.4 0.053 13.7 0.3 1.2 1 0 0 1 1 1 0 Latarcin precursor MecA PF05389.7 CCF51109.1 - 0.084 12.4 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) CBM_21 PF03370.8 CCF51110.1 - 4e-30 104.1 0.1 7.1e-30 103.2 0.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Dicty_REP PF05086.7 CCF51110.1 - 5.2 4.6 3.3 7.4 4.1 2.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAD_binding_3 PF01494.14 CCF51111.1 - 1.2e-56 192.3 0.1 2e-55 188.3 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 CCF51111.1 - 1.2e-18 67.2 0.0 2.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 CCF51111.1 - 3e-06 27.1 0.0 1.1e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF51111.1 - 7.9e-05 21.7 0.0 0.00024 20.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF51111.1 - 0.00018 20.1 0.0 0.00029 19.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CCF51111.1 - 0.00068 18.6 0.1 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCF51111.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCF51111.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF51111.1 - 0.002 17.0 0.1 0.0043 15.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCF51111.1 - 0.003 17.6 0.0 0.0094 16.0 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF51111.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCF51111.1 - 0.027 14.8 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CCF51111.1 - 0.052 12.9 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 CCF51111.1 - 0.06 11.9 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.5 CCF51111.1 - 0.19 10.5 0.0 5.4 5.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 CCF51111.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain rve PF00665.21 CCF51114.1 - 7.5e-13 48.6 0.1 1.4e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF51115.1 - 1.1e-30 106.4 0.0 1.6e-27 96.0 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Med14 PF08638.6 CCF51115.1 - 0.093 11.9 1.6 0.14 11.3 0.5 1.8 2 0 0 2 2 2 0 Mediator complex subunit MED14 MitMem_reg PF13012.1 CCF51116.1 - 5.8e-17 61.8 0.4 9.8e-17 61.1 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCF51116.1 - 2.8e-13 49.6 0.0 1.1e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPR_MLP1_2 PF07926.7 CCF51117.1 - 0.015 15.0 2.2 0.031 14.0 1.5 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tmemb_cc2 PF10267.4 CCF51117.1 - 1.4 7.4 13.4 0.017 13.7 1.6 2.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Senescence PF06911.7 CCF51118.1 - 1.6e-45 155.0 5.3 2.7e-45 154.2 3.7 1.4 1 0 0 1 1 1 1 Senescence-associated protein Laminin_G_1 PF00054.18 CCF51118.1 - 0.025 14.5 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Laminin G domain DUF1691 PF07950.6 CCF51119.1 - 9.2e-05 22.3 6.0 0.15 11.9 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1691) RhoGAP PF00620.22 CCF51120.1 - 4.9e-38 130.1 0.0 9.2e-38 129.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RVT_2 PF07727.9 CCF51121.1 - 2.9e-36 124.7 0.0 1.4e-31 109.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.21 CCF51123.1 - 7.1e-44 148.6 0.0 8e-44 148.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAD_binding_6 PF00970.19 CCF51124.1 - 1.4e-31 108.5 0.0 2.2e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCF51124.1 - 2.9e-27 95.3 0.0 4.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCF51124.1 - 1e-07 31.9 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCF51124.1 - 0.00041 20.3 0.0 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain TOM13 PF08219.6 CCF51124.1 - 0.016 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 Outer membrane protein TOM13 DUF3850 PF12961.2 CCF51124.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) Nup160 PF11715.3 CCF51125.1 - 2.2e-119 399.1 0.3 2.2e-119 399.1 0.2 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Peptidase_M20 PF01546.23 CCF51126.1 - 1.6e-24 86.4 0.0 2.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCF51126.1 - 2e-13 50.0 0.0 5.2e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3256 PF11644.3 CCF51126.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3256) Mitofilin PF09731.4 CCF51128.1 - 7.7e-144 480.5 27.9 8.9e-144 480.3 19.3 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF479 PF04336.7 CCF51128.1 - 0.42 10.7 4.6 2.8 8.0 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function, DUF479 2Fe-2S_thioredx PF01257.14 CCF51129.1 - 1.1e-61 206.6 0.1 1.5e-61 206.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF1636 PF07845.6 CCF51129.1 - 0.044 14.0 0.1 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) Fer4 PF00037.22 CCF51130.1 - 4.4e-14 51.3 16.9 1.9e-08 33.5 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 CCF51130.1 - 2.3e-12 47.1 10.8 3.7e-12 46.4 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 CCF51130.1 - 8.8e-10 38.2 5.3 7.5e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 CCF51130.1 - 1.2e-09 38.7 8.0 0.00012 22.7 0.5 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 CCF51130.1 - 2e-09 37.1 23.1 7.4e-08 32.0 9.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCF51130.1 - 3.3e-09 36.8 11.1 5.9e-09 36.0 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 CCF51130.1 - 2.7e-08 33.2 14.6 0.00011 21.9 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 CCF51130.1 - 4.3e-08 33.0 20.1 2.2e-05 24.3 8.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 CCF51130.1 - 9.8e-08 31.5 18.0 0.00083 19.1 3.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 CCF51130.1 - 3.5e-06 27.2 9.5 0.00075 19.7 7.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 CCF51130.1 - 4e-06 26.7 12.3 0.00089 19.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 CCF51130.1 - 2.2e-05 24.7 9.0 0.014 15.8 0.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 CCF51130.1 - 0.00014 22.1 11.1 0.037 14.4 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 CCF51130.1 - 0.00019 21.9 7.9 0.074 13.6 0.4 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 CCF51130.1 - 0.051 14.1 18.1 0.088 13.4 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 CCF51130.1 - 0.17 12.0 4.4 0.48 10.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain RNase_H2-Ydr279 PF09468.5 CCF51131.1 - 1.2e-16 60.7 0.0 2.8e-16 59.5 0.0 1.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) VCBS PF13517.1 CCF51132.1 - 3.7e-20 72.0 22.4 9.1e-08 32.3 1.1 6.1 5 1 1 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CCF51132.1 - 1.3e-18 66.1 9.1 0.00012 21.6 0.0 6.5 6 0 0 6 6 6 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 CCF51132.1 - 0.0011 18.3 3.4 13 5.2 0.0 5.2 5 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region DUF1214 PF06742.6 CCF51132.1 - 0.063 13.7 0.6 5.2 7.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1214) V_ATPase_I PF01496.14 CCF51133.1 - 4.6e-264 877.9 0.0 5.3e-264 877.7 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.7 CCF51133.1 - 0.61 10.5 3.0 8.7 6.7 0.6 2.9 3 0 0 3 3 3 0 SlyX Cep57_MT_bd PF06657.8 CCF51133.1 - 0.71 9.8 6.3 0.16 11.9 0.4 2.8 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 TPR_1 PF00515.23 CCF51134.1 - 1.8e-26 90.5 10.1 1.5e-05 24.3 0.0 8.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCF51134.1 - 1.1e-23 82.6 18.0 7.5e-11 41.5 0.4 5.8 4 1 0 5 5 5 3 TPR repeat APC8 PF04049.8 CCF51134.1 - 2.1e-21 76.1 0.0 2.4e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 CCF51134.1 - 4.1e-19 66.9 18.4 0.00081 19.1 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF51134.1 - 1.6e-18 65.0 2.7 4.3e-05 22.9 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCF51134.1 - 1.5e-14 53.6 23.6 1.9e-06 27.6 0.3 7.7 5 1 5 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF51134.1 - 5.1e-12 45.3 15.4 0.0021 18.5 0.1 9.7 5 2 5 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 CCF51134.1 - 7.3e-12 45.2 10.7 0.00057 19.9 0.5 4.4 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCF51134.1 - 6.2e-11 41.2 10.4 0.46 10.4 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCF51134.1 - 6.7e-10 39.3 2.9 1.8e-08 34.8 1.0 8.0 7 2 3 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCF51134.1 - 1.2e-09 37.6 3.2 0.012 15.7 0.2 7.2 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF51134.1 - 6.6e-06 26.3 9.1 0.0053 17.0 0.0 5.7 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCF51134.1 - 2.7e-05 24.3 12.6 0.37 11.3 0.2 8.0 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCF51134.1 - 2.8e-05 23.8 19.1 0.089 12.6 0.1 6.6 5 1 1 7 7 7 3 Tetratricopeptide repeat Ribosomal_S6e PF01092.14 CCF51135.1 - 4.8e-58 194.3 1.1 5.6e-58 194.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 CCF51136.1 - 2e-30 104.4 0.4 3.5e-30 103.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CCF51136.1 - 1.8e-22 78.8 0.0 3.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 CCF51136.1 - 0.028 14.1 0.0 0.063 12.9 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Arrestin_N PF00339.24 CCF51137.1 - 0.15 11.9 0.0 0.81 9.4 0.0 2.2 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain LRR_6 PF13516.1 CCF51138.1 - 1.1e-05 24.9 5.0 27 5.2 0.0 7.8 8 1 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.1 CCF51138.1 - 0.0039 16.9 7.3 8.8 6.1 0.1 5.0 4 2 1 5 5 4 2 Leucine rich repeat LRR_4 PF12799.2 CCF51138.1 - 0.004 16.7 11.7 0.53 9.9 0.8 5.8 3 3 2 6 6 6 3 Leucine Rich repeats (2 copies) DUF500 PF04366.7 CCF51139.1 - 4.9e-38 129.4 0.0 1.3e-37 127.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCF51139.1 - 3.6e-14 51.8 0.1 7.1e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF51139.1 - 1.1e-13 50.5 0.0 2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF51139.1 - 2.3e-10 39.8 0.0 6.2e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_9 PF00759.14 CCF51140.1 - 2.2e-94 316.8 12.5 2.5e-92 310.0 8.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 VSP PF03302.8 CCF51140.1 - 0.48 9.0 2.1 0.49 8.9 0.6 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein Arf PF00025.16 CCF51141.1 - 3.7e-67 224.9 0.0 4.3e-67 224.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCF51141.1 - 1e-13 50.7 1.3 3.8e-09 35.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CCF51141.1 - 2.2e-13 49.8 0.0 2.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CCF51141.1 - 1.9e-10 41.2 0.0 2.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCF51141.1 - 2.6e-09 36.6 0.0 3.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CCF51141.1 - 3.2e-09 36.2 0.0 3.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF51141.1 - 1.9e-08 34.2 0.0 4.4e-08 33.0 0.0 1.5 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF51141.1 - 2e-06 27.3 0.0 2.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCF51141.1 - 0.0027 17.0 0.0 0.01 15.1 0.0 2.0 1 1 1 2 2 2 1 Ferrous iron transport protein B CdhD PF03599.11 CCF51141.1 - 0.034 12.6 0.0 0.042 12.3 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AAA_17 PF13207.1 CCF51141.1 - 0.058 14.2 0.0 0.12 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CCF51141.1 - 0.063 12.8 0.0 0.19 11.3 0.0 1.6 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PIG-U PF06728.8 CCF51142.1 - 7.9e-112 373.8 16.5 1e-111 373.5 11.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DEAD PF00270.24 CCF51143.1 - 3.5e-37 127.4 0.0 1.3e-35 122.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF51143.1 - 1e-18 66.9 0.9 2.1e-17 62.7 0.3 2.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain Adaptin_N PF01602.15 CCF51144.1 - 5e-149 496.9 10.3 5.9e-149 496.7 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCF51144.1 - 1.4e-24 86.5 0.2 2.6e-24 85.7 0.2 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CCF51144.1 - 2.6e-09 37.2 1.8 0.1 12.8 0.1 6.0 5 3 2 7 7 7 2 HEAT repeats RIX1 PF08167.7 CCF51144.1 - 0.00035 20.2 0.4 0.0069 16.0 0.1 3.1 1 1 0 2 2 2 1 rRNA processing/ribosome biogenesis HEAT PF02985.17 CCF51144.1 - 0.00041 20.1 0.3 23 5.3 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat NPCBM_assoc PF10633.4 CCF51144.1 - 0.00076 19.4 0.7 0.0021 18.0 0.5 1.7 1 0 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Cnd1 PF12717.2 CCF51144.1 - 0.0027 17.5 4.7 0.066 13.0 0.5 3.7 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 CCF51144.1 - 0.0076 15.8 6.0 0.012 15.2 0.2 3.6 3 2 1 4 4 4 1 TATA-binding protein interacting (TIP20) Arm PF00514.18 CCF51144.1 - 0.069 12.9 0.1 18 5.3 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Hist_deacetyl PF00850.14 CCF51145.1 - 1.4e-79 267.6 0.0 1.8e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Nuc_sug_transp PF04142.10 CCF51146.1 - 5.1e-09 35.5 0.2 8.4e-09 34.8 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 CCF51146.1 - 1.2e-08 34.2 7.8 2.2e-08 33.3 5.4 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCF51146.1 - 0.00016 21.3 17.2 0.044 13.4 5.7 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CCF51146.1 - 0.00055 19.9 3.7 0.00055 19.9 2.6 3.6 3 1 1 4 4 4 1 EamA-like transporter family HECT PF00632.20 CCF51147.1 - 9.7e-93 310.7 0.0 1.4e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCF51147.1 - 8.9e-33 111.7 19.2 4e-11 42.5 2.1 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCF51147.1 - 3.3e-16 58.8 0.1 8.2e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain Lectin_N PF03954.9 CCF51149.1 - 0.0023 17.3 4.5 0.0056 16.0 0.4 2.2 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain DUF1192 PF06698.6 CCF51149.1 - 0.079 12.7 0.3 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) FliJ PF02050.11 CCF51149.1 - 0.88 9.6 9.0 0.25 11.3 2.9 2.3 2 1 0 2 2 2 0 Flagellar FliJ protein Utp11 PF03998.8 CCF51149.1 - 1.3 8.7 7.6 1.8 8.3 4.7 1.6 1 1 0 1 1 1 0 Utp11 protein TACC PF05010.9 CCF51149.1 - 2.1 8.0 9.8 5 6.8 6.8 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF972 PF06156.8 CCF51149.1 - 3.5 8.0 6.3 1.1 9.6 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 CCF51149.1 - 4.8 7.1 11.7 2.2 8.2 2.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Complex1_LYR PF05347.10 CCF51150.1 - 4.1e-07 29.6 0.3 1.3e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCF51150.1 - 4.4e-05 23.6 1.7 0.0004 20.5 1.2 2.5 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L31 PF01197.13 CCF51150.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 RNase_T PF00929.19 CCF51152.1 - 7.6e-10 39.3 0.0 1.3e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 Exonuclease SAP PF02037.22 CCF51152.1 - 4e-09 35.7 2.1 4e-09 35.7 1.4 2.1 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 CCF51152.1 - 0.014 14.8 0.1 0.035 13.6 0.1 1.7 1 0 0 1 1 1 0 HeH/LEM domain RRM_1 PF00076.17 CCF51153.1 - 8.2e-06 25.3 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51153.1 - 4.6e-05 23.3 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCF51153.1 - 5.6e-05 22.7 2.2 5.6e-05 22.7 1.5 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 CCF51153.1 - 0.0025 17.6 1.4 0.0031 17.3 0.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger RRM_5 PF13893.1 CCF51153.1 - 0.0029 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2256 PF10013.4 CCF51153.1 - 0.087 12.5 0.4 0.087 12.5 0.3 3.3 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-CCCH_2 PF14608.1 CCF51153.1 - 0.65 10.0 4.3 0.83 9.7 2.0 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type AMPKBI PF04739.10 CCF51154.1 - 3.1e-28 97.5 0.2 2.4e-27 94.7 0.0 2.4 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain MAT1 PF06391.8 CCF51155.1 - 1e-38 132.9 22.1 1.4e-38 132.5 15.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 CCF51155.1 - 0.0002 20.9 9.8 0.0015 18.1 7.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF51155.1 - 0.00032 20.3 7.6 0.001 18.7 5.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCF51155.1 - 0.00071 19.1 8.5 0.0027 17.3 6.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CCF51155.1 - 0.0033 16.9 6.8 0.044 13.3 1.6 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CCF51155.1 - 0.0075 16.2 10.5 0.13 12.3 7.9 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ISL3 PF14690.1 CCF51155.1 - 0.018 15.0 0.5 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_2 PF13639.1 CCF51155.1 - 0.09 12.6 9.0 1.5 8.6 7.0 2.1 1 1 1 2 2 2 0 Ring finger domain Ycf1 PF05758.7 CCF51155.1 - 0.2 9.3 5.8 0.22 9.1 4.0 1.1 1 0 0 1 1 1 0 Ycf1 DZR PF12773.2 CCF51155.1 - 0.31 10.8 7.1 1.2 8.9 4.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CCF51155.1 - 0.42 10.1 5.9 1.4 8.4 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF572 PF04502.8 CCF51155.1 - 0.82 8.8 18.7 1.2 8.2 13.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0547 PF10571.4 CCF51155.1 - 0.96 9.2 6.4 0.52 10.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 CCF51155.1 - 1.9 8.4 10.7 6.7 6.7 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain CAF-1_p150 PF11600.3 CCF51155.1 - 2.5 7.4 38.5 3.8 6.8 26.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2146 PF10220.4 CCF51155.1 - 3.7 5.3 11.2 4.6 5.0 7.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) RINGv PF12906.2 CCF51156.1 - 1.3e-09 37.9 6.7 2.3e-09 37.1 4.7 1.4 1 0 0 1 1 1 1 RING-variant domain Cytochrom_C552 PF02335.10 CCF51156.1 - 0.058 12.0 0.5 0.092 11.4 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c552 Flavi_NS2B PF01002.14 CCF51157.1 - 0.047 13.2 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B GPI-anchored PF10342.4 CCF51157.1 - 0.13 12.7 0.4 0.24 11.9 0.2 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ecl1 PF12855.2 CCF51158.1 - 0.00012 21.2 0.3 0.00025 20.2 0.2 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF2116 PF09889.4 CCF51158.1 - 0.02 14.6 0.8 0.05 13.4 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Uricase PF01014.13 CCF51160.1 - 1.6e-63 212.8 0.0 2.4e-36 124.8 0.2 2.0 2 0 0 2 2 2 2 Uricase GLTP PF08718.6 CCF51161.1 - 1.5e-43 148.3 0.0 2.9e-43 147.4 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) F_bP_aldolase PF01116.15 CCF51162.1 - 4.6e-98 327.8 0.0 5.2e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II WD40 PF00400.27 CCF51163.1 - 3.4e-12 45.7 6.8 0.0051 16.6 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CCF51163.1 - 0.043 14.0 0.1 19 5.7 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Dehydratase_SU PF02287.10 CCF51163.1 - 0.39 10.4 5.0 0.12 12.1 0.3 2.2 1 1 1 2 2 2 0 Dehydratase small subunit CDC73 PF05179.9 CCF51163.1 - 0.98 8.7 4.4 0.5 9.6 0.3 2.2 1 1 1 2 2 2 0 RNA pol II accessory factor, Cdc73 family ABC1 PF03109.11 CCF51164.1 - 1.6e-23 82.9 0.0 8.5e-16 58.0 0.0 2.5 2 0 0 2 2 2 2 ABC1 family AdoMet_MTase PF07757.8 CCF51165.1 - 1.6e-33 115.1 0.0 2.6e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 CCF51165.1 - 7e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF51165.1 - 0.0085 16.6 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF51165.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CCF51165.1 - 0.032 13.8 0.1 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Tom5 PF10642.4 CCF51166.1 - 9e-11 41.2 0.1 9.9e-11 41.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase S1 PF00575.18 CCF51167.1 - 6.4e-57 189.5 24.3 2.9e-11 43.2 1.5 9.6 9 0 0 9 9 9 8 S1 RNA binding domain TPR_16 PF13432.1 CCF51167.1 - 2.6e-08 34.3 0.2 0.35 11.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 CCF51167.1 - 4.7e-07 29.8 0.1 4.7e-07 29.8 0.1 4.9 4 2 2 6 6 6 1 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CCF51167.1 - 1e-05 25.7 0.0 0.0036 17.5 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF51167.1 - 6.2e-05 23.2 0.0 1.4 9.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Nop14 PF04147.7 CCF51167.1 - 0.0026 15.7 44.9 0.16 9.8 11.8 3.2 3 0 0 3 3 3 3 Nop14-like family SDA1 PF05285.7 CCF51167.1 - 0.0038 16.5 21.9 0.0038 16.5 15.2 3.3 3 0 0 3 3 3 2 SDA1 tRNA_bind PF01588.15 CCF51167.1 - 0.024 14.4 1.0 0.12 12.2 0.6 2.3 2 0 0 2 2 2 0 Putative tRNA binding domain TPR_12 PF13424.1 CCF51167.1 - 0.042 13.7 0.3 13 5.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 CCF51168.1 - 1.5e-40 139.0 36.2 2e-39 135.3 24.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF51168.1 - 2.4e-16 59.3 1.7 2.4e-16 59.3 1.2 3.1 4 0 0 4 4 4 2 Sugar (and other) transporter APC10 PF03256.11 CCF51169.1 - 1.7e-46 158.2 0.0 2.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 CCF51169.1 - 3 6.2 4.7 5.1 5.4 3.3 1.3 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 CCF51169.1 - 4.2 7.5 20.6 18 5.5 11.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family zf-Tim10_DDP PF02953.10 CCF51170.1 - 3e-22 77.6 1.0 3.7e-22 77.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.16 CCF51171.1 - 9.3e-21 73.6 0.0 1.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Methyltransf_19 PF04672.7 CCF51171.1 - 0.15 11.3 0.0 0.56 9.4 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl methyltransferase NAD_binding_1 PF00175.16 CCF51172.1 - 7.3e-05 23.3 0.0 0.011 16.3 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCF51172.1 - 0.0021 18.1 0.0 0.0053 16.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Exo_endo_phos PF03372.18 CCF51173.1 - 1.2e-12 48.2 0.3 1.4e-12 48.0 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DKCLD PF08068.7 CCF51174.1 - 5e-30 103.2 0.3 5e-29 99.9 0.0 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCF51174.1 - 8e-25 87.7 0.3 7.6e-22 78.0 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCF51174.1 - 1.9e-20 72.3 0.8 4.2e-20 71.2 0.5 1.6 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 CCF51174.1 - 1 8.9 23.6 1.7 8.3 16.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ribosomal_L22e PF01776.12 CCF51175.1 - 2.3e-47 159.6 0.8 2.7e-47 159.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DevR PF01905.11 CCF51175.1 - 0.02 13.7 0.1 0.026 13.3 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 WD40 PF00400.27 CCF51176.1 - 5.9e-26 89.3 13.4 1.3e-07 31.2 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCF51176.1 - 0.055 13.2 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M28 PF04389.12 CCF51177.1 - 2.1e-25 89.4 0.1 3.8e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCF51177.1 - 2.8e-06 26.9 0.0 4.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LTV PF04180.9 CCF51178.1 - 4.2e-50 171.5 14.8 4.2e-50 171.5 10.2 3.5 2 2 0 2 2 2 1 Low temperature viability protein EXOSC1 PF10447.4 CCF51179.1 - 9.1e-29 99.2 0.0 1.4e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CCF51179.1 - 3.8e-05 22.8 0.7 0.00019 20.6 0.5 2.3 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pkinase PF00069.20 CCF51180.1 - 1e-53 182.1 0.0 2.8e-53 180.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51180.1 - 1.1e-24 86.9 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF51180.1 - 0.012 15.3 0.4 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Protocadherin PF08374.6 CCF51181.1 - 0.0072 15.9 1.1 0.0098 15.5 0.8 1.2 1 0 0 1 1 1 1 Protocadherin GPI-anchored PF10342.4 CCF51182.1 - 5.9e-12 45.9 4.5 5.9e-12 45.9 3.1 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MDFI PF15316.1 CCF51182.1 - 0.13 12.2 5.9 0.24 11.3 4.1 1.5 1 0 0 1 1 1 0 MyoD family inhibitor Pescadillo_N PF06732.6 CCF51183.1 - 1.7e-116 388.4 0.2 1.7e-116 388.4 0.1 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 CCF51183.1 - 0.014 15.4 0.0 0.049 13.7 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF3818 PF12825.2 CCF51184.1 - 4.1e-43 147.3 0.0 9.6e-43 146.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCF51184.1 - 4e-27 94.4 0.0 7.7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 PX-associated Acyl-CoA_dh_1 PF00441.19 CCF51185.1 - 2.5e-34 118.5 3.4 2.5e-34 118.5 2.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF51185.1 - 1.1e-17 63.3 0.1 2.6e-17 62.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCF51185.1 - 6.4e-16 58.9 0.2 2.6e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCF51185.1 - 5.3e-15 55.8 5.6 2.1e-14 53.9 2.2 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PGM_PMM_III PF02880.11 CCF51185.1 - 0.017 15.1 0.3 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Glyco_hydro_20 PF00728.17 CCF51186.1 - 2.7e-78 263.5 0.0 3.8e-78 263.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 CCF51186.1 - 1.4e-14 54.8 0.0 3.4e-14 53.6 0.0 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 CCF51186.1 - 3e-05 24.5 0.1 0.00073 20.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Fe_dep_repress PF01325.14 CCF51186.1 - 0.13 12.2 0.0 0.47 10.4 0.0 1.9 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain MFS_1 PF07690.11 CCF51187.1 - 7.5e-18 64.3 44.1 1.5e-17 63.3 27.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily UCH PF00443.24 CCF51188.1 - 5.6e-33 114.1 0.0 8.5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCF51188.1 - 2.7e-10 40.2 0.2 4.5e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CCF51188.1 - 4e-08 33.0 0.0 1.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ODC_AZ PF02100.12 CCF51189.1 - 1.3e-25 88.9 0.0 2.2e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Es2 PF09751.4 CCF51190.1 - 1.7e-74 251.6 0.3 2.1e-74 251.4 0.2 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 ADH_zinc_N PF00107.21 CCF51191.1 - 2.7e-14 52.8 0.4 1.1e-13 50.7 0.0 2.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF51191.1 - 4.2e-11 42.5 0.0 8.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SURF2 PF05477.6 CCF51191.1 - 0.081 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) zf-C2H2 PF00096.21 CCF51192.1 - 0.11 12.8 0.5 0.3 11.5 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type WD40 PF00400.27 CCF51194.1 - 1.1e-52 174.1 19.6 1.1e-08 34.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat 4HBT_2 PF13279.1 CCF51195.1 - 1.1e-14 54.9 0.1 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CCF51195.1 - 2.6e-06 27.4 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CCF51195.1 - 0.0032 16.4 0.6 0.01 14.8 0.4 1.9 1 1 0 1 1 1 1 Acyl-ACP thioesterase PPR_2 PF13041.1 CCF51196.1 - 7e-17 61.1 0.1 9.6e-06 25.4 0.0 7.8 9 0 0 9 9 9 2 PPR repeat family PPR_3 PF13812.1 CCF51196.1 - 2.9e-09 36.4 10.8 0.16 12.2 0.0 9.6 11 0 0 11 11 11 2 Pentatricopeptide repeat domain PPR PF01535.15 CCF51196.1 - 5.9e-06 25.9 18.2 0.03 14.3 0.0 8.3 11 0 0 11 11 11 2 PPR repeat PPR_1 PF12854.2 CCF51196.1 - 0.012 15.0 5.3 2.6 7.6 0.1 5.1 6 0 0 6 6 6 0 PPR repeat GATA PF00320.22 CCF51197.1 - 3.3e-14 51.9 5.4 6.5e-14 50.9 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger Ycf1 PF05758.7 CCF51197.1 - 0.067 10.9 8.3 0.11 10.2 5.8 1.3 1 0 0 1 1 1 0 Ycf1 Hepar_II_III PF07940.8 CCF51198.1 - 3.7e-09 36.5 0.5 1.3e-08 34.8 0.4 2.0 1 0 0 1 1 1 1 Heparinase II/III-like protein Pyr_redox_3 PF13738.1 CCF51199.1 - 2.7e-23 83.1 0.0 1.8e-22 80.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF51199.1 - 3.7e-11 42.8 0.0 1.5e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCF51199.1 - 1.6e-10 40.4 0.0 9.1e-07 28.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 CCF51199.1 - 1.1e-09 37.0 1.3 2.3e-08 32.7 0.9 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 CCF51199.1 - 1.1e-06 27.7 0.0 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCF51199.1 - 1.3e-05 25.0 0.0 0.021 14.6 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCF51199.1 - 1.6e-05 24.8 0.0 0.0047 16.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF51199.1 - 9.5e-05 21.4 0.0 0.028 13.3 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 CCF51199.1 - 0.00017 20.8 0.0 0.027 13.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 CCF51199.1 - 0.0062 15.4 0.1 1.8 7.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 CCF51199.1 - 0.024 15.0 0.0 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Tim17 PF02466.14 CCF51200.1 - 1.2e-33 115.8 4.4 1.4e-33 115.6 3.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sec5 PF15469.1 CCF51201.1 - 1.7e-55 187.5 0.0 1.2e-54 184.7 0.0 2.4 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 CCF51201.1 - 0.00033 20.4 0.0 0.0036 17.1 0.0 2.8 2 0 0 2 2 2 1 Vps51/Vps67 CK2S PF15011.1 CCF51201.1 - 0.049 13.4 0.8 0.57 9.9 0.0 2.9 2 1 0 2 2 2 0 Casein Kinase 2 substrate zf-ZPR1 PF03367.8 CCF51201.1 - 0.17 10.9 1.4 0.59 9.2 0.1 2.3 2 0 0 2 2 2 0 ZPR1 zinc-finger domain PA28_beta PF02252.13 CCF51202.1 - 4.8e-52 175.4 0.0 6.9e-52 174.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CCF51202.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit ABC_membrane PF00664.18 CCF51203.1 - 2.8e-61 207.3 28.6 2.7e-32 112.2 4.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF51203.1 - 1.3e-54 184.2 0.0 2.7e-30 105.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCF51203.1 - 3.2e-12 46.9 0.0 0.095 12.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 CCF51203.1 - 4.2e-10 39.2 2.1 0.00022 20.5 0.0 3.7 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF51203.1 - 6.3e-07 28.8 0.9 0.026 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CCF51203.1 - 6.4e-07 29.8 0.3 0.082 13.4 0.1 3.5 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 CCF51203.1 - 5.1e-06 26.4 0.2 0.016 15.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 CCF51203.1 - 2.7e-05 24.2 2.3 0.14 12.1 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.1 CCF51203.1 - 3.3e-05 23.3 1.5 0.029 13.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCF51203.1 - 6.1e-05 23.4 2.9 0.23 11.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CCF51203.1 - 0.00015 22.6 0.4 0.74 10.6 0.0 3.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CCF51203.1 - 0.00037 20.0 1.0 0.061 12.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 CCF51203.1 - 0.00049 19.3 2.4 0.36 9.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CCF51203.1 - 0.00053 19.1 0.5 0.33 10.0 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin ArgK PF03308.11 CCF51203.1 - 0.00077 18.3 0.9 0.15 10.7 0.2 2.3 2 0 0 2 2 2 1 ArgK protein T2SE PF00437.15 CCF51203.1 - 0.002 17.1 0.1 2.4 6.9 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein Dynamin_N PF00350.18 CCF51203.1 - 0.002 17.9 3.9 0.62 9.8 0.1 2.9 2 0 0 2 2 2 2 Dynamin family MobB PF03205.9 CCF51203.1 - 0.003 17.2 0.5 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCF51203.1 - 0.0078 15.6 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 CCF51203.1 - 0.0085 15.9 2.2 1.9 8.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCF51203.1 - 0.0097 15.6 0.0 1 9.0 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase ATP_bind_1 PF03029.12 CCF51203.1 - 0.0098 15.4 0.7 1 8.8 0.1 2.8 3 0 0 3 3 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CCF51203.1 - 0.019 15.1 1.6 4.9 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 CCF51203.1 - 0.021 14.3 3.3 4.1 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CCF51203.1 - 0.024 14.3 0.3 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 CCF51203.1 - 0.036 13.5 2.0 15 5.0 0.1 3.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 CCF51203.1 - 0.048 13.1 1.3 7 6.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 CCF51203.1 - 0.071 12.0 0.7 3.5 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 CCF51203.1 - 0.081 11.4 5.8 1.7 7.1 0.0 3.5 4 0 0 4 4 4 0 Predicted ATPase of the ABC class KAP_NTPase PF07693.9 CCF51203.1 - 0.11 11.4 0.0 3.5 6.5 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain DUF87 PF01935.12 CCF51203.1 - 0.34 10.6 3.7 0.64 9.7 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CCF51203.1 - 1.6 9.0 5.1 15 5.9 0.1 3.4 3 0 0 3 3 3 0 AAA domain NPL4 PF05021.10 CCF51204.1 - 5.3e-101 337.8 0.0 7.2e-101 337.3 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCF51204.1 - 3.3e-66 221.4 2.2 5.6e-66 220.7 1.5 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region zf-RanBP PF00641.13 CCF51204.1 - 0.00036 19.5 1.0 0.00036 19.5 0.7 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.3 CCF51204.1 - 0.00051 20.2 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Adeno_E1A PF02703.9 CCF51204.1 - 0.019 14.4 0.5 0.15 11.4 0.4 2.1 2 0 0 2 2 2 0 Early E1A protein Cript PF10235.4 CCF51204.1 - 0.027 14.8 3.4 2.7 8.3 0.0 2.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-TRM13_CCCH PF11722.3 CCF51204.1 - 0.035 13.4 0.4 0.077 12.3 0.3 1.6 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Med3 PF11593.3 CCF51204.1 - 0.52 9.5 9.1 1 8.5 6.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRM_1 PF00076.17 CCF51206.1 - 2.9e-12 46.0 0.1 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51206.1 - 2.9e-11 43.1 0.0 2.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51206.1 - 0.00031 20.5 0.0 0.00077 19.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.10 CCF51207.1 - 3.4e-22 77.4 0.5 4.1e-22 77.2 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Complex1_51K PF01512.12 CCF51209.1 - 2.8e-49 166.7 0.0 4.5e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CCF51209.1 - 9.9e-20 69.4 0.5 2.2e-19 68.3 0.4 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CCF51209.1 - 1e-06 28.5 0.0 2.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain Sugar_tr PF00083.19 CCF51211.1 - 8e-104 347.7 13.5 9.6e-104 347.4 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF51211.1 - 1.6e-22 79.7 21.3 1.6e-22 79.7 14.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily CDC45 PF02724.9 CCF51211.1 - 1.9 6.4 4.3 2.7 5.9 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 CCF51212.1 - 2e-67 227.0 0.0 3.3e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51212.1 - 8.1e-48 162.7 0.0 1.3e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51212.1 - 0.00054 19.0 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like V-ATPase_H_N PF03224.9 CCF51212.1 - 0.019 14.0 1.3 0.13 11.3 0.9 2.2 1 1 0 1 1 1 0 V-ATPase subunit H Aldo_ket_red PF00248.16 CCF51213.1 - 1.9e-27 95.8 0.0 2.8e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family RVT_1 PF00078.22 CCF51213.1 - 7.5e-11 41.7 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAXNEB PF05625.6 CCF51214.1 - 3e-40 138.2 0.0 1.5e-25 89.8 0.0 3.3 3 0 0 3 3 3 3 PAXNEB protein KaiC PF06745.8 CCF51214.1 - 0.21 10.6 0.0 0.8 8.7 0.0 1.8 2 0 0 2 2 2 0 KaiC Ferritin_2 PF13668.1 CCF51215.1 - 7.5e-39 132.8 1.8 1.5e-38 131.8 1.2 1.5 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.11 CCF51216.1 - 2.4e-29 102.1 37.8 1.4e-28 99.6 13.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Utp11 PF03998.8 CCF51217.1 - 2.4e-71 240.3 5.4 2.9e-71 240.1 3.7 1.1 1 0 0 1 1 1 1 Utp11 protein DUF3220 PF11516.3 CCF51217.1 - 0.052 13.5 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) CtaG_Cox11 PF04442.9 CCF51218.1 - 2.9e-54 183.0 0.0 4.5e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Herpes_capsid PF06112.6 CCF51218.1 - 2.1 8.3 11.3 3.4 7.6 7.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ORC4_C PF14629.1 CCF51220.1 - 3.8e-53 179.9 0.0 6e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CCF51220.1 - 9.8e-33 113.6 1.3 2.6e-32 112.3 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CCF51220.1 - 4.1e-06 27.0 0.2 0.028 14.6 0.1 2.9 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF51220.1 - 2e-05 24.7 0.0 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCF51220.1 - 4e-05 23.0 0.1 0.00012 21.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 CCF51220.1 - 0.0056 15.6 0.1 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CCF51220.1 - 0.013 15.2 0.1 0.066 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CCF51220.1 - 0.014 15.0 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Phage_sheath_1 PF04984.9 CCF51220.1 - 0.032 12.6 0.3 0.054 11.9 0.2 1.3 1 0 0 1 1 1 0 Phage tail sheath protein ABC_tran PF00005.22 CCF51220.1 - 0.083 13.1 0.0 0.22 11.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.16 CCF51220.1 - 0.085 12.0 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 CCF51220.1 - 0.09 11.4 0.0 0.52 8.9 0.0 2.0 1 1 0 1 1 1 0 G-protein alpha subunit Pox_A32 PF04665.7 CCF51220.1 - 0.15 11.3 0.1 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein SNF2_N PF00176.18 CCF51221.1 - 3.2e-51 173.9 0.0 5.3e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF51221.1 - 1.1e-15 57.2 0.0 3.6e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCF51221.1 - 7.6e-08 31.5 0.0 2.8e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 CCF51221.1 - 8e-07 28.6 2.0 0.0024 17.5 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.1 CCF51221.1 - 2.5e-06 26.9 3.8 0.005 16.1 0.6 2.9 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain ResIII PF04851.10 CCF51221.1 - 8.6e-05 22.4 0.0 0.00058 19.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.24 CCF51221.1 - 8.7e-05 22.1 5.8 0.0025 17.4 1.0 3.0 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 CCF51221.1 - 0.016 14.9 7.0 0.31 10.7 0.0 3.6 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac_C PF08542.6 CCF51222.1 - 1.4e-21 76.2 0.0 7.2e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCF51222.1 - 9.6e-13 48.1 0.1 7e-11 42.0 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCF51222.1 - 4.3e-12 46.3 0.0 7.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCF51222.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCF51222.1 - 8.5e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF51222.1 - 1.1e-05 25.5 0.1 0.00031 20.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 CCF51222.1 - 1.3e-05 24.1 0.0 0.014 14.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCF51222.1 - 0.00011 22.3 0.1 0.13 12.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 CCF51222.1 - 0.00025 20.1 0.0 0.00065 18.8 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCF51222.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CCF51222.1 - 0.0019 17.7 0.0 0.0047 16.4 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CCF51222.1 - 0.0023 17.4 0.0 0.24 10.8 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 CCF51222.1 - 0.016 14.3 0.0 0.28 10.2 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCF51222.1 - 0.018 14.7 0.2 0.065 12.9 0.0 2.0 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 CCF51222.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 CCF51222.1 - 0.025 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCF51222.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CCF51222.1 - 0.049 13.3 0.1 0.43 10.2 0.0 2.2 1 1 1 2 2 2 0 NTPase ArgK PF03308.11 CCF51222.1 - 0.088 11.5 0.0 0.22 10.2 0.0 1.6 1 1 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 CCF51222.1 - 0.092 12.1 0.1 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 CCF51222.1 - 0.093 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1302 PF06980.6 CCF51222.1 - 0.2 10.1 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) PPR_1 PF12854.2 CCF51222.1 - 0.29 10.6 1.2 0.48 9.9 0.2 1.8 2 0 0 2 2 1 0 PPR repeat DUF605 PF04652.11 CCF51223.1 - 3.6 6.8 31.1 5.6 6.2 21.6 1.4 1 0 0 1 1 1 0 Vta1 like PAP2 PF01569.16 CCF51224.1 - 1.1e-13 51.0 5.6 1.5e-13 50.5 3.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 CCF51224.1 - 0.00019 21.2 1.2 0.0019 17.9 0.1 2.4 2 0 0 2 2 2 1 Divergent PAP2 family DUF2614 PF11023.3 CCF51224.1 - 1.1 9.1 2.9 0.97 9.2 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2614) Kelch_5 PF13854.1 CCF51225.1 - 1.8e-36 123.5 9.8 2.1e-09 37.1 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CCF51225.1 - 4.3e-35 119.0 15.7 1.4e-09 37.8 0.0 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCF51225.1 - 1.7e-33 114.1 13.3 2.1e-07 30.6 0.2 7.4 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_1 PF01344.20 CCF51225.1 - 4.5e-29 99.7 6.7 4.8e-10 38.8 0.6 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CCF51225.1 - 1.5e-27 94.6 8.7 1.8e-09 37.3 0.3 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCF51225.1 - 2.1e-18 65.2 12.1 0.0024 17.5 0.1 6.9 6 1 0 6 6 6 5 Kelch motif Reo_sigmaC PF04582.7 CCF51225.1 - 0.14 11.3 50.1 0.05 12.7 4.9 5.1 1 1 5 6 6 6 0 Reovirus sigma C capsid protein Bestrophin PF01062.16 CCF51225.1 - 2.5 6.9 2.6 12 4.7 1.8 2.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel zf-BED PF02892.10 CCF51227.1 - 0.16 11.7 0.4 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 BED zinc finger RR_TM4-6 PF06459.7 CCF51228.1 - 0.1 12.4 0.2 0.95 9.3 0.1 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TLD PF07534.11 CCF51229.1 - 4e-28 98.1 0.0 2.3e-25 89.2 0.0 2.6 2 0 0 2 2 2 2 TLD RhoGEF PF00621.15 CCF51230.1 - 8.9e-43 146.2 0.0 1.5e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 CCF51230.1 - 1.1e-12 47.2 1.0 2.5e-05 23.7 0.0 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF51230.1 - 8.4e-09 35.0 6.6 0.00031 20.4 0.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CCF51230.1 - 3.5e-06 26.2 5.2 1.4 9.2 0.1 4.6 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CCF51230.1 - 8.6e-05 22.1 5.4 1.9 9.0 0.4 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CCF51230.1 - 2.1 8.6 5.1 31 5.0 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat CPSF_A PF03178.10 CCF51231.1 - 5.2e-94 314.9 0.0 1.2e-92 310.4 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CCF51231.1 - 8.9e-72 241.8 0.0 2e-71 240.6 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 CCF51231.1 - 0.33 10.9 1.7 0.82 9.6 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF4407 PF14362.1 CCF51232.1 - 4.7e-05 22.4 1.1 7.1e-05 21.9 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Tweety PF04906.8 CCF51232.1 - 0.03 12.7 2.0 0.31 9.4 0.0 2.0 2 0 0 2 2 2 0 Tweety NfeD PF01957.13 CCF51232.1 - 0.21 11.7 2.0 0.22 11.6 0.8 1.6 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Tetraspannin PF00335.15 CCF51232.1 - 0.54 9.4 13.3 1.9 7.7 9.2 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF4149 PF13664.1 CCF51232.1 - 5.5 7.1 12.4 1.2 9.2 5.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) SMC_N PF02463.14 CCF51233.1 - 2.7e-26 92.1 0.0 4.9e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCF51233.1 - 1.8e-11 44.7 28.7 1.8e-11 44.7 19.9 5.6 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.1 CCF51233.1 - 7.2e-07 29.4 2.6 0.0012 18.8 0.6 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF51233.1 - 3.6e-05 23.2 0.1 7.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CCF51233.1 - 0.00024 20.3 2.4 0.00024 20.3 1.6 2.4 2 1 0 2 2 2 1 AAA ATPase domain Reo_sigmaC PF04582.7 CCF51233.1 - 0.00074 18.7 9.6 0.24 10.5 0.1 4.2 2 2 1 4 4 4 2 Reovirus sigma C capsid protein DUF724 PF05266.9 CCF51233.1 - 0.0009 18.9 1.4 0.0009 18.9 1.0 5.7 3 2 2 5 5 3 1 Protein of unknown function (DUF724) APG6 PF04111.7 CCF51233.1 - 0.0011 18.0 19.3 0.0011 18.0 13.4 5.9 3 2 3 6 6 4 2 Autophagy protein Apg6 IncA PF04156.9 CCF51233.1 - 0.0015 18.1 21.8 0.0015 18.1 15.1 5.9 2 2 3 5 5 5 2 IncA protein Tropomyosin PF00261.15 CCF51233.1 - 0.0022 17.1 8.5 0.0022 17.1 5.9 5.0 2 2 2 4 4 3 1 Tropomyosin AAA_13 PF13166.1 CCF51233.1 - 0.0054 15.2 74.2 0.083 11.3 0.2 5.3 3 2 2 5 5 5 4 AAA domain ABC_tran PF00005.22 CCF51233.1 - 0.017 15.4 0.3 0.017 15.4 0.2 5.3 4 1 0 4 4 3 0 ABC transporter COG5 PF10392.4 CCF51233.1 - 0.05 13.5 0.2 0.05 13.5 0.1 5.1 6 0 0 6 6 6 0 Golgi transport complex subunit 5 AAA_18 PF13238.1 CCF51233.1 - 0.27 11.5 0.1 0.27 11.5 0.1 4.7 4 1 0 4 4 3 0 AAA domain ApbA_C PF08546.6 CCF51234.1 - 3.6e-36 123.9 0.0 5.7e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCF51234.1 - 2e-22 79.2 0.0 9.8e-18 64.0 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF3591 PF12157.3 CCF51235.1 - 6.2e-191 634.7 2.7 1e-190 634.0 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCF51235.1 - 0.0002 20.9 3.0 0.00048 19.7 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle NTR2 PF15458.1 CCF51236.1 - 1.9e-38 132.1 3.3 1.9e-38 132.1 2.3 2.2 2 0 0 2 2 2 1 Nineteen complex-related protein 2 DUF1253 PF06862.7 CCF51237.1 - 6.8e-159 528.9 0.4 8.8e-159 528.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ORC6 PF05460.8 CCF51237.1 - 0.22 10.5 6.5 0.37 9.8 4.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-R PF06729.7 CCF51237.1 - 1.5 8.5 6.1 26 4.4 2.3 2.4 2 0 0 2 2 2 0 Kinetochore component, CENP-R MMR_HSR1 PF01926.18 CCF51238.1 - 5.4e-16 58.5 0.1 9.6e-15 54.5 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF51238.1 - 4.5e-05 22.7 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CCF51238.1 - 6.7e-05 22.1 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCF51238.1 - 0.0057 16.4 0.8 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.11 CCF51238.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CCF51238.1 - 0.028 14.9 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Sporozoite_P67 PF05642.6 CCF51238.1 - 0.12 10.1 3.9 0.15 9.8 0.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Img2 PF05046.9 CCF51239.1 - 1.9e-28 98.4 0.0 4.7e-28 97.2 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SecE PF00584.15 CCF51240.1 - 4.2e-14 51.8 0.0 4.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Ribosomal_L29 PF00831.18 CCF51241.1 - 3.6e-19 68.2 2.5 3.6e-19 68.2 1.7 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 CCF51241.1 - 0.0072 16.5 2.3 0.0094 16.1 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF896 PF05979.7 CCF51241.1 - 0.12 12.0 0.3 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) HiaBD2 PF15403.1 CCF51241.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) PGC7_Stella PF15549.1 CCF51241.1 - 0.6 10.0 5.0 0.75 9.7 3.5 1.1 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain RNA_pol_Rpb2_4 PF04566.8 CCF51241.1 - 0.63 9.8 2.9 0.51 10.1 0.5 1.9 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 4 SF3b10 PF07189.6 CCF51243.1 - 2.4e-29 100.9 0.0 2.8e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Zn_clus PF00172.13 CCF51245.1 - 0.0003 20.6 15.1 0.00044 20.1 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF2_N PF00176.18 CCF51246.1 - 2.9e-70 236.4 0.8 6e-70 235.3 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 CCF51246.1 - 3.1e-52 176.3 19.0 3.1e-52 176.3 13.2 3.2 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 CCF51246.1 - 1.1e-12 47.5 0.0 2.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF51246.1 - 1.6e-05 24.8 0.0 5.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Swi5 PF07061.6 CCF51249.1 - 5.7e-15 54.8 0.2 8.9e-15 54.2 0.1 1.3 1 0 0 1 1 1 1 Swi5 DUF2959 PF11172.3 CCF51249.1 - 0.0074 16.0 0.3 0.018 14.8 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2959) Alpha-E PF04168.7 CCF51249.1 - 0.022 14.1 0.1 0.026 13.9 0.1 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Ribosomal_L29 PF00831.18 CCF51249.1 - 0.06 13.0 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein Pex14_N PF04695.8 CCF51250.1 - 2.1e-16 60.1 0.8 2.1e-16 60.1 0.5 3.5 3 2 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CENP-B_dimeris PF09026.5 CCF51250.1 - 3.4 7.9 12.1 10 6.4 4.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RVT_2 PF07727.9 CCF51251.1 - 6.7e-06 25.2 0.0 9.6e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GDI PF00996.13 CCF51252.1 - 5.6e-200 664.2 0.0 6.3e-200 664.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCF51252.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2404 PF10296.4 CCF51253.1 - 6.9e-30 103.0 0.0 1.2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) SET PF00856.23 CCF51254.1 - 2.1e-08 34.6 0.0 3.6e-06 27.3 0.0 2.6 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 CCF51254.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region HLH PF00010.21 CCF51255.1 - 0.00032 20.3 0.0 0.001 18.6 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain SnoaL PF07366.7 CCF51255.1 - 0.068 12.7 0.4 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase GHMP_kinases_N PF00288.21 CCF51256.1 - 3.8e-13 49.2 1.0 9.6e-13 48.0 0.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCF51256.1 - 4.9e-06 26.6 0.0 1.9e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases C terminal Telomerase_RBD PF12009.3 CCF51257.1 - 2.6e-35 121.3 0.9 5.6e-35 120.2 0.2 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCF51257.1 - 5.7e-13 48.7 0.0 8.1e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 CCF51258.1 - 1.1e-46 159.1 0.0 3.8e-28 98.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51258.1 - 2.4e-18 66.1 0.0 2.6e-17 62.7 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51258.1 - 0.00034 19.6 0.0 0.00067 18.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF51258.1 - 0.0093 15.7 0.1 0.08 12.6 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCF51258.1 - 0.016 14.2 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDUF_B12 PF08122.7 CCF51260.1 - 0.094 12.4 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family Ank_2 PF12796.2 CCF51261.1 - 1.4e-10 41.3 0.2 3.4e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCF51261.1 - 2.6e-09 37.3 0.0 5.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CCF51261.1 - 3.8e-09 35.9 0.3 1.8e-06 27.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCF51261.1 - 1.2e-08 34.8 0.2 1.4e-06 28.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF51261.1 - 3.9e-08 32.7 0.1 9.1e-05 22.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-CCCH_2 PF14608.1 CCF51261.1 - 9.8e-07 28.5 7.3 9.8e-07 28.5 5.0 2.6 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CCF51261.1 - 0.00017 21.1 11.3 0.0018 17.8 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PPR_2 PF13041.1 CCF51262.1 - 5.4e-08 32.6 0.4 0.92 9.5 0.0 5.2 5 0 0 5 5 5 4 PPR repeat family Tup_N PF08581.5 CCF51263.1 - 0.0018 18.4 2.3 0.0018 18.4 1.6 21.8 6 6 19 27 27 27 3 Tup N-terminal Nup54 PF13874.1 CCF51263.1 - 0.0023 17.5 7.8 0.0023 17.5 5.4 19.6 2 1 17 21 21 21 2 Nucleoporin complex subunit 54 bZIP_2 PF07716.10 CCF51264.1 - 5.7e-09 35.6 13.7 5.7e-09 35.6 9.5 3.5 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 CCF51264.1 - 0.0028 17.5 14.1 0.0028 17.5 9.8 2.7 2 1 0 2 2 2 1 bZIP transcription factor Phlebovirus_NSM PF07246.6 CCF51264.1 - 0.045 12.9 0.2 0.045 12.9 0.2 1.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M TSC22 PF01166.13 CCF51264.1 - 0.076 12.9 0.1 0.076 12.9 0.1 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family AAA_23 PF13476.1 CCF51264.1 - 3 8.1 11.7 1.1 9.5 2.1 2.3 2 0 0 2 2 2 0 AAA domain Spore_III_AF PF09581.5 CCF51264.1 - 4.5 7.0 13.2 2.4 8.0 1.7 2.9 2 1 1 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Adaptin_N PF01602.15 CCF51265.1 - 6.9e-111 371.1 0.0 9.4e-111 370.6 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCF51265.1 - 9.7e-55 184.5 0.7 1.9e-54 183.6 0.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCF51265.1 - 2.4e-13 50.1 0.5 0.00073 19.7 0.0 6.5 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.17 CCF51265.1 - 2.6e-05 23.9 4.8 3 8.1 0.1 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_PBS PF03130.11 CCF51265.1 - 0.16 12.4 2.2 11 6.8 0.0 4.6 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat zf-Nse PF11789.3 CCF51266.1 - 2.3e-14 52.6 0.0 5.1e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCF51266.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain Transcrip_act PF04949.8 CCF51266.1 - 0.0073 15.9 1.9 0.025 14.1 0.4 2.1 2 0 0 2 2 2 1 Transcriptional activator zf-RING_UBOX PF13445.1 CCF51266.1 - 0.03 14.0 0.2 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 CCF51266.1 - 0.038 13.7 0.1 0.078 12.7 0.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CCF51266.1 - 0.05 13.4 1.2 0.12 12.2 0.2 2.0 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 CCF51266.1 - 0.1 12.6 1.2 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SIP PF04954.8 CCF51266.1 - 0.15 12.4 1.8 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Siderophore-interacting protein CTP_synth_N PF06418.9 CCF51267.1 - 3.9e-116 386.9 0.1 5.4e-116 386.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CCF51267.1 - 1.7e-49 167.8 0.0 1.5e-39 135.4 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 CCF51267.1 - 0.0019 17.6 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 CCF51267.1 - 0.094 12.1 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Cse1 PF08506.5 CCF51268.1 - 0.1 11.1 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Cse1 Ribosomal_S28e PF01200.13 CCF51269.1 - 1.9e-31 107.6 2.9 2e-31 107.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF336 PF03928.9 CCF51270.1 - 1.2e-14 54.2 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Ras PF00071.17 CCF51271.1 - 1.4e-54 183.8 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF51271.1 - 1.2e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF51271.1 - 5.2e-06 25.8 0.0 6.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family UQ_con PF00179.21 CCF51272.1 - 5.7e-23 80.8 0.0 1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CCF51272.1 - 0.085 12.5 0.1 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 UEV domain Rav1p_C PF12234.3 CCF51273.1 - 3.4e-195 649.8 0.0 4.4e-195 649.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 CCF51273.1 - 1.1 9.1 11.8 17 5.4 0.0 6.4 6 0 0 6 6 6 0 WD domain, G-beta repeat PP-binding PF00550.20 CCF51274.1 - 6.9e-15 55.0 0.9 9.9e-15 54.5 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCF51274.1 - 4.2e-08 33.1 0.7 6e-08 32.6 0.5 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 CCF51274.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF1493 PF07377.7 CCF51274.1 - 0.15 12.2 0.2 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L17 PF01196.14 CCF51275.1 - 1.8e-30 105.3 0.0 4.5e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L17 Osmo_MPGsynth PF09488.5 CCF51275.1 - 0.057 12.1 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) PPR_2 PF13041.1 CCF51276.1 - 4.9e-10 39.2 0.0 0.76 9.7 0.0 6.2 4 1 2 6 6 6 4 PPR repeat family PPR_3 PF13812.1 CCF51276.1 - 2.3e-08 33.6 8.4 0.11 12.7 0.0 7.3 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 CCF51276.1 - 0.0005 19.8 0.2 16 5.7 0.0 5.2 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 CCF51276.1 - 0.0053 16.1 0.0 1.1 8.7 0.0 3.5 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.1 CCF51276.1 - 0.0083 16.4 1.8 0.038 14.3 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat CbiD PF01888.12 CCF51277.1 - 0.06 12.3 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 CbiD FAM110_N PF14161.1 CCF51277.1 - 0.086 13.1 0.5 0.41 10.9 0.2 2.3 2 1 0 2 2 2 0 Centrosome-associated N terminus PH PF00169.24 CCF51278.1 - 1.9e-05 24.7 0.0 0.00011 22.3 0.0 2.3 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 CCF51278.1 - 0.1 12.8 0.0 3.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Pleckstrin homology domain Heme_oxygenase PF01126.15 CCF51279.1 - 5e-20 71.9 0.1 1.8e-15 57.0 0.0 2.7 2 1 0 2 2 2 2 Heme oxygenase Bin3 PF06859.7 CCF51280.1 - 2.7e-14 53.0 0.0 5.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.1 CCF51280.1 - 5.9e-08 32.4 0.1 1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF51280.1 - 1.8e-07 31.6 0.0 4.2e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 CCF51280.1 - 6.6e-06 25.5 0.0 1.9e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.1 CCF51280.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF51280.1 - 0.00036 20.9 0.0 0.00091 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF51280.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCF51280.1 - 0.0059 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF51280.1 - 0.024 15.0 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CCF51280.1 - 0.14 12.6 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF2414 PF10309.4 CCF51281.1 - 3.3e-06 26.6 0.0 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 CCF51281.1 - 4e-05 23.4 0.0 0.00011 22.1 0.0 1.6 2 0 0 2 2 2 1 RNA binding domain RRM_6 PF14259.1 CCF51281.1 - 0.026 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF51281.1 - 0.034 13.9 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Rsm22 PF09243.5 CCF51282.1 - 2.2e-36 125.2 0.8 5e-16 58.5 0.0 4.9 4 1 1 5 5 5 4 Mitochondrial small ribosomal subunit Rsm22 Ima1_N PF09779.4 CCF51283.1 - 4.9e-18 65.8 1.1 4.9e-18 65.8 0.8 1.9 2 0 0 2 2 2 1 Ima1 N-terminal domain Lyase_1 PF00206.15 CCF51284.1 - 1.6e-119 398.7 0.0 2.3e-119 398.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCF51284.1 - 1.8e-20 72.7 0.4 1e-18 67.1 0.0 2.6 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 CCF51284.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain MMR_HSR1 PF01926.18 CCF51285.1 - 2.2e-10 40.5 0.0 8.3e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCF51285.1 - 0.036 14.0 0.1 0.091 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 CCF51285.1 - 0.078 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 CCF51285.1 - 0.08 11.6 0.5 0.2 10.3 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.18 CCF51285.1 - 0.084 12.6 1.7 1.4 8.7 0.2 2.8 2 1 0 2 2 2 0 Dynamin family AAA_29 PF13555.1 CCF51285.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Carn_acyltransf PF00755.15 CCF51286.1 - 1.6e-176 587.9 0.1 1.9e-176 587.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AMP-binding PF00501.23 CCF51288.1 - 8.3e-46 156.2 0.0 1.2e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 CCF51288.1 - 1.2e-12 47.8 0.7 2.3e-12 46.9 0.5 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 CCF51288.1 - 1.3e-12 46.6 1.6 0.00037 19.8 0.0 6.9 7 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 CCF51288.1 - 2e-09 38.2 2.4 1.5e-05 25.8 0.0 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 CCF51288.1 - 0.041 13.4 11.0 7.6 6.1 0.2 5.4 4 2 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 CCF51288.1 - 0.7 8.3 0.0 14 4.0 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Peptidase_M1 PF01433.15 CCF51289.1 - 1.4e-105 353.5 1.3 1.4e-67 228.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 CCF51289.1 - 1.5e-66 224.8 0.4 2.1e-66 224.3 0.3 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCF51289.1 - 5.3e-14 52.3 0.2 1.6e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase MA superfamily SKN1 PF03935.10 CCF51294.1 - 7e-188 624.8 2.6 8.8e-188 624.5 1.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 CCF51294.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Neurensin PfkB PF00294.19 CCF51295.1 - 3.7e-63 213.4 2.6 4.3e-63 213.2 1.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCF51295.1 - 4.6e-05 22.7 0.1 0.0001 21.6 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase SNF2_N PF00176.18 CCF51296.1 - 6.7e-65 218.8 0.0 9.2e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCF51296.1 - 7.2e-28 96.6 0.0 1.4e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CCF51296.1 - 2e-11 43.5 0.0 5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CCF51296.1 - 7.1e-06 25.7 13.0 1.2e-05 24.9 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF51296.1 - 1.8e-05 24.6 13.7 3e-05 23.9 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF51296.1 - 4.3e-05 23.1 12.9 7.3e-05 22.4 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCF51296.1 - 0.008 15.8 14.1 0.014 15.0 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF51296.1 - 0.86 9.4 5.4 1.8 8.4 3.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCF51296.1 - 2.1 8.3 7.4 4.4 7.3 5.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Cupin_8 PF13621.1 CCF51297.1 - 4.3e-13 49.3 0.0 1.3e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCF51297.1 - 9.5e-08 32.2 0.0 1.5e-06 28.4 0.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CCF51297.1 - 2.5e-05 23.6 0.1 0.00012 21.4 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein F-box-like PF12937.2 CCF51297.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 F-box-like Raptor_N PF14538.1 CCF51298.1 - 1.1e-61 207.1 0.1 3.2e-61 205.7 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 CCF51298.1 - 1.4e-10 40.5 2.3 0.9 9.5 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCF51298.1 - 7.9e-06 25.6 0.0 0.004 16.9 0.0 2.9 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 CCF51298.1 - 9.6e-06 25.2 6.9 0.03 14.3 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat WD40 PF00400.27 CCF51299.1 - 6.8e-24 82.8 12.5 4.6e-10 38.9 0.2 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCF51299.1 - 2e-20 72.4 0.1 4.3e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CCF51299.1 - 2.2e-05 24.2 0.1 0.00051 19.8 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Zip PF02535.17 CCF51300.1 - 2.4e-26 92.4 42.8 1.7e-21 76.5 21.8 3.5 2 1 0 2 2 2 2 ZIP Zinc transporter CHD5 PF04420.9 CCF51301.1 - 7.9e-42 142.6 0.2 1.2e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 CHD5-like protein DivIC PF04977.10 CCF51301.1 - 0.06 12.8 2.4 0.14 11.6 0.0 2.6 2 1 1 3 3 3 0 Septum formation initiator RCC1_2 PF13540.1 CCF51302.1 - 6.1e-06 25.7 4.0 0.011 15.2 0.1 4.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCF51302.1 - 0.00016 21.8 2.1 3.7 7.8 0.2 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 CCF51304.1 - 2.9e-15 55.6 0.0 2.2e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51304.1 - 1.2e-14 53.8 0.0 2.4e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51304.1 - 6.7e-09 35.6 0.0 0.00038 20.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF51304.1 - 0.045 13.5 0.6 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 Limkain b1 HMG_box PF00505.14 CCF51305.1 - 5.2e-16 58.6 0.1 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF51305.1 - 1.4e-10 41.4 0.1 4.1e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-binding PF00249.26 CCF51305.1 - 4.9e-05 23.3 0.0 9.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3635 PF12330.3 CCF51306.1 - 8.4e-18 64.2 0.0 3e-17 62.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 CCF51306.1 - 0.0014 17.8 0.0 0.0039 16.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51306.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Ribosomal_L1 PF00687.16 CCF51307.1 - 7.4e-21 74.5 0.0 5.7e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family GARS_A PF01071.14 CCF51308.1 - 3.2e-71 238.9 0.0 4.7e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCF51308.1 - 1.4e-30 105.7 0.0 4.6e-30 104.0 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 CCF51308.1 - 1.1e-26 92.8 0.2 2.1e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 CCF51308.1 - 1.3e-26 93.4 0.0 2.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCF51308.1 - 1.1e-16 60.7 0.5 4.2e-16 58.9 0.3 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.9 CCF51308.1 - 0.15 11.8 0.0 0.41 10.5 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.12 CCF51308.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Pyr_redox PF00070.22 CCF51309.1 - 1.1e-15 57.7 0.2 8.9e-12 45.2 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF51309.1 - 8.5e-12 45.3 0.0 1e-06 28.7 0.0 4.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF51309.1 - 9e-06 25.8 0.2 0.27 11.2 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF51309.1 - 0.0036 16.2 0.2 0.29 9.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_5 PF12695.2 CCF51309.1 - 0.0053 16.5 1.3 0.057 13.1 0.2 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Trp_halogenase PF04820.9 CCF51309.1 - 0.023 13.3 0.1 2.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase DUF4403 PF14356.1 CCF51309.1 - 0.15 10.2 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) Lycopene_cycl PF05834.7 CCF51309.1 - 0.17 10.7 0.0 0.48 9.2 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Macoilin PF09726.4 CCF51309.1 - 3.7 5.7 16.5 5.5 5.1 11.4 1.3 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 CCF51311.1 - 7.5e-27 93.9 30.5 1.7e-26 92.7 19.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Corona_nucleoca PF00937.13 CCF51311.1 - 0.092 11.6 7.8 0.14 11.0 5.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein NMT1 PF09084.6 CCF51312.1 - 6.7e-74 248.1 0.0 8.9e-74 247.7 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 CCF51312.1 - 0.0011 18.3 0.6 0.56 9.5 0.0 3.1 2 1 1 3 3 3 2 NMT1-like family PCI PF01399.22 CCF51313.1 - 2.8e-20 72.6 0.8 7.6e-20 71.2 0.6 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CCF51313.1 - 1.5e-10 41.0 0.2 2.9e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 CCF51313.1 - 0.0013 18.3 1.0 0.0063 16.1 0.1 2.6 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 CCF51313.1 - 0.008 16.8 0.7 0.46 11.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCF51313.1 - 0.017 15.0 0.1 0.25 11.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF51313.1 - 0.02 14.6 2.5 0.93 9.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCF51313.1 - 0.04 13.8 0.2 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCF51313.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF51313.1 - 0.21 12.3 3.1 15 6.5 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Acyltransferase PF01553.16 CCF51314.1 - 5.3e-21 74.4 0.0 1.5e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase MarR PF01047.17 CCF51314.1 - 0.012 15.3 0.0 0.071 12.8 0.0 2.3 3 0 0 3 3 3 0 MarR family RVT_1 PF00078.22 CCF51315.1 - 2.5e-07 30.2 0.0 8.6e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CCF51315.1 - 0.00013 21.7 0.0 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 Phage integrase family Peptidase_M18 PF02127.10 CCF51316.1 - 1.9e-163 544.0 0.0 2.1e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCF51316.1 - 3.2e-05 22.8 0.0 0.039 12.7 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase IBN_N PF03810.14 CCF51317.1 - 7.1e-07 29.0 0.2 2.7e-05 24.0 0.0 3.5 4 1 0 4 4 4 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 CCF51317.1 - 4.3e-05 22.0 0.1 0.014 13.6 0.0 2.8 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus HEAT PF02985.17 CCF51317.1 - 0.00063 19.6 1.5 1.5 9.1 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat Cse1 PF08506.5 CCF51317.1 - 0.00075 18.1 0.0 0.0025 16.4 0.0 1.8 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 CCF51317.1 - 0.02 14.7 0.1 0.23 11.3 0.0 2.9 3 1 0 3 3 3 0 Exportin 1-like protein Katanin_con80 PF13925.1 CCF51317.1 - 0.068 12.9 0.1 3.8 7.2 0.0 2.9 2 0 0 2 2 2 0 con80 domain of Katanin Fungal_trans_2 PF11951.3 CCF51318.1 - 3.6e-09 35.7 4.2 5.6e-09 35.0 0.1 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF51318.1 - 4.4e-08 32.9 8.3 1.1e-07 31.6 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain peroxidase PF00141.18 CCF51321.1 - 1.9e-84 282.7 0.0 4e-45 154.0 0.0 2.4 2 1 0 2 2 2 2 Peroxidase AA_permease_2 PF13520.1 CCF51322.1 - 8.7e-45 153.0 49.3 1.1e-44 152.6 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF51322.1 - 2.2e-19 69.1 46.6 9.1e-19 67.1 26.7 2.0 2 0 0 2 2 2 2 Amino acid permease DUF997 PF06196.7 CCF51322.1 - 0.17 11.4 0.1 0.17 11.4 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF997) SieB PF14163.1 CCF51322.1 - 4.8 6.7 8.3 3 7.4 0.1 2.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Cu_amine_oxid PF01179.15 CCF51323.1 - 4.6e-158 526.2 0.0 5.6e-158 526.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 CCF51323.1 - 1.2e-07 31.6 0.1 2.9e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 CCF51323.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain FF PF01846.14 CCF51324.1 - 3e-24 84.7 14.4 1.6e-07 31.1 0.0 6.8 6 1 0 6 6 6 6 FF domain WW PF00397.21 CCF51324.1 - 0.00014 21.6 7.8 0.0003 20.5 2.6 2.5 2 0 0 2 2 2 1 WW domain DUF3752 PF12572.3 CCF51325.1 - 5e-15 55.9 50.6 8.8e-09 35.6 16.8 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3752) SMC_N PF02463.14 CCF51326.1 - 1.1e-17 64.0 0.0 2.6e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCF51326.1 - 1e-11 45.5 22.0 1e-11 45.5 15.3 5.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CCF51326.1 - 2e-08 34.5 2.4 0.0012 18.9 0.0 3.0 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CCF51326.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Uso1_p115_C PF04871.8 CCF51326.1 - 0.014 15.2 0.4 0.014 15.2 0.3 7.3 2 2 3 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_15 PF13175.1 CCF51326.1 - 0.03 13.3 4.4 0.091 11.7 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 CCF51326.1 - 0.14 11.5 0.0 0.14 11.5 0.0 3.1 3 1 1 4 4 4 0 AAA domain AAA_13 PF13166.1 CCF51326.1 - 0.63 8.4 58.9 0.5 8.7 10.9 5.0 3 2 2 5 5 5 0 AAA domain Seadorna_VP6 PF07407.6 CCF51326.1 - 1.7 7.3 8.5 3 6.5 5.9 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein ZYG-11_interact PF05884.7 CCF51326.1 - 7.8 5.4 7.9 0.71 8.8 1.6 2.1 2 0 0 2 2 2 0 Interactor of ZYG-11 Abhydrolase_1 PF00561.15 CCF51327.1 - 1.8e-25 89.8 0.2 5.5e-23 81.7 0.2 3.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF51327.1 - 7.5e-05 22.7 3.2 0.033 14.0 0.1 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Pol_alpha_B_N PF08418.5 CCF51327.1 - 2.6 7.5 5.6 4.2 6.8 3.9 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal 7tm_1 PF00001.16 CCF51329.1 - 5.1e-12 45.4 1.5 9e-12 44.6 1.0 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 CCF51329.1 - 1.5e-10 40.9 14.1 1.5e-10 40.9 9.8 1.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CCF51329.1 - 0.00049 19.8 0.1 0.0018 18.0 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2946 PF11162.3 CCF51329.1 - 1.9 8.7 11.0 0.16 12.2 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) DnaJ PF00226.26 CCF51330.1 - 1.3e-13 50.4 0.0 2.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain NOC3p PF07540.6 CCF51331.1 - 7.6e-22 77.4 0.7 2.4e-20 72.6 0.0 3.3 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 CCF51331.1 - 1.5e-10 40.7 1.2 1.5e-10 40.7 0.8 2.2 2 0 0 2 2 2 1 CBF/Mak21 family 60KD_IMP PF02096.15 CCF51331.1 - 0.17 11.5 3.1 0.35 10.4 2.2 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein zf-CCHC PF00098.18 CCF51333.1 - 0.0034 17.2 5.1 0.017 15.0 3.5 2.4 1 0 0 1 1 1 1 Zinc knuckle MlrC_C PF07171.7 CCF51335.1 - 0.039 13.4 0.3 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 MlrC C-terminus rve PF00665.21 CCF51337.1 - 2e-13 50.4 0.0 3.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF51337.1 - 1.2e-06 28.1 0.6 3.2e-06 26.6 0.4 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain D-ser_dehydrat PF14031.1 CCF51337.1 - 0.032 14.4 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Putative serine dehydratase domain Amidase PF01425.16 CCF51338.1 - 2.4e-71 240.8 0.0 2.4e-62 211.2 0.0 2.1 2 0 0 2 2 2 2 Amidase XFP_N PF09364.5 CCF51339.1 - 1.8e-130 434.8 0.0 2.9e-130 434.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 CCF51339.1 - 1.8e-55 187.3 0.0 3.6e-55 186.2 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 CCF51339.1 - 1.2e-48 165.3 0.3 5e-48 163.2 0.0 2.1 2 1 0 2 2 2 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 CCF51339.1 - 0.0059 16.1 0.1 0.016 14.8 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UAF_Rrn10 PF05234.6 CCF51339.1 - 0.0075 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Transket_pyr PF02779.19 CCF51339.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Acetate_kinase PF00871.12 CCF51340.1 - 4.3e-67 226.3 0.0 4.7e-65 219.6 0.0 2.8 1 1 0 1 1 1 1 Acetokinase family Glyco_hydro_10 PF00331.15 CCF51341.1 - 3e-100 335.3 0.0 3.4e-100 335.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 CCF51341.1 - 0.038 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF4339 PF14237.1 CCF51341.1 - 0.044 13.3 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) LIP PF03583.9 CCF51343.1 - 8.3e-58 195.8 0.1 1.2e-57 195.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 CCF51343.1 - 0.0003 20.5 0.0 0.0008 19.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF51343.1 - 0.0014 18.5 0.6 0.0059 16.5 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF51343.1 - 0.016 14.4 0.0 0.079 12.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family PUF PF00806.14 CCF51344.1 - 5.7e-62 201.8 9.9 7.7e-09 34.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat UDG PF03167.14 CCF51345.1 - 0.18 11.2 5.2 0.25 10.7 0.1 2.5 2 1 0 2 2 2 0 Uracil DNA glycosylase superfamily Macoilin PF09726.4 CCF51345.1 - 1.6 6.9 12.4 2.1 6.5 8.6 1.3 1 0 0 1 1 1 0 Transmembrane protein RFC1 PF08519.7 CCF51346.1 - 4.3e-50 169.4 0.0 2.4e-48 163.7 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 CCF51346.1 - 1.2e-10 41.3 0.0 2.7e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CCF51346.1 - 6.9e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF51346.1 - 2.6e-05 24.3 0.0 7.8e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CCF51346.1 - 0.0009 18.0 0.1 0.021 13.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 CCF51346.1 - 0.0014 18.2 0.0 0.0041 16.8 0.0 1.8 2 0 0 2 2 1 1 NACHT domain AAA_19 PF13245.1 CCF51346.1 - 0.0038 16.9 0.0 0.02 14.6 0.0 2.2 1 1 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCF51346.1 - 0.004 17.9 0.0 0.02 15.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF51346.1 - 0.0067 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCF51346.1 - 0.0089 16.1 0.0 0.12 12.5 0.0 2.6 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 CCF51346.1 - 0.023 14.7 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CCF51346.1 - 0.025 14.9 0.6 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 CCF51346.1 - 0.039 12.9 0.0 0.079 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CCF51346.1 - 0.1 12.3 0.1 0.9 9.2 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF3246 PF11596.3 CCF51346.1 - 2.1 7.5 20.2 5.7 6.1 14.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Ebola_NP PF05505.7 CCF51346.1 - 4.9 5.0 18.8 8.3 4.3 13.1 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Rgp1 PF08737.5 CCF51347.1 - 2.3e-90 303.6 0.0 4.2e-90 302.7 0.0 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 CCF51347.1 - 6.6e-05 22.7 0.0 0.012 15.4 0.0 3.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCF51347.1 - 0.0012 18.9 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Abhydro_lipase PF04083.11 CCF51348.1 - 6.5e-16 57.4 0.0 1.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 CCF51348.1 - 3.9e-05 23.4 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF51348.1 - 0.098 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold Bromodomain PF00439.20 CCF51349.1 - 2.8e-30 104.0 0.3 9.7e-18 63.8 0.0 3.4 2 1 0 2 2 2 2 Bromodomain DUF2730 PF10805.3 CCF51350.1 - 0.056 13.1 6.2 1.4 8.6 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF3584 PF12128.3 CCF51350.1 - 0.1 9.9 26.2 0.14 9.4 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MDMPI_N PF11716.3 CCF51350.1 - 2 8.8 12.7 2.2 8.7 3.0 3.6 1 1 2 3 3 3 0 Mycothiol maleylpyruvate isomerase N-terminal domain AAA_13 PF13166.1 CCF51350.1 - 4.3 5.6 21.2 6.5 5.0 14.7 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CCF51350.1 - 4.4 5.0 18.1 0.61 7.8 8.6 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family RVT_2 PF07727.9 CCF51352.1 - 4.8e-15 55.2 0.0 5.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tn7_Tnp_TnsA_C PF08721.6 CCF51352.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal rve PF00665.21 CCF51353.1 - 9.6e-08 32.1 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF2917 PF11142.3 CCF51353.1 - 0.063 12.4 0.1 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) DUF3154 PF11351.3 CCF51353.1 - 1.8 8.2 4.1 4.1 7.1 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) CMD PF02627.15 CCF51354.1 - 0.03 14.1 0.3 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family RVT_2 PF07727.9 CCF51357.1 - 2.1e-38 131.7 0.0 2.3e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fructosamin_kin PF03881.9 CCF51358.1 - 3.1e-32 111.7 0.0 3.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 CCF51358.1 - 4.5e-07 29.8 0.0 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family HECT PF00632.20 CCF51359.1 - 8.7e-97 324.0 0.0 1.3e-96 323.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Med21 PF11221.3 CCF51359.1 - 0.2 11.6 1.8 6 6.8 0.0 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex UQ_con PF00179.21 CCF51360.1 - 6.8e-28 96.8 0.0 7.9e-28 96.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF51360.1 - 1.5e-05 24.8 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCF51360.1 - 0.0038 17.1 0.0 0.0045 16.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CCF51360.1 - 0.01 15.5 0.1 0.015 15.0 0.0 1.3 1 1 0 1 1 1 1 UEV domain Ferrochelatase PF00762.14 CCF51361.1 - 6.3e-104 347.3 0.0 7.5e-104 347.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 CCF51361.1 - 0.0008 19.4 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 CbiX Synaptobrevin PF00957.16 CCF51362.1 - 2.6e-32 110.2 2.5 3e-32 110.0 1.7 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 CCF51362.1 - 0.43 10.1 3.0 0.58 9.6 2.1 1.3 1 1 0 1 1 1 0 Retroviral envelope protein MAPEG PF01124.13 CCF51364.1 - 4.4e-28 97.4 2.9 5.1e-28 97.2 2.0 1.1 1 0 0 1 1 1 1 MAPEG family zf-4CXXC_R1 PF10497.4 CCF51365.1 - 1.5e-13 50.7 11.1 3e-13 49.7 7.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_4 PF15227.1 CCF51365.1 - 0.011 15.5 1.8 0.011 15.5 1.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AT_hook PF02178.14 CCF51365.1 - 0.16 11.6 15.8 0.7 9.7 1.8 2.9 2 0 0 2 2 2 0 AT hook motif Pkinase PF00069.20 CCF51366.1 - 4.1e-56 190.0 0.0 1.6e-55 188.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51366.1 - 1.9e-27 95.9 0.2 6.5e-19 68.0 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF51366.1 - 1.5e-06 27.3 0.0 0.00041 19.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCF51366.1 - 0.0029 17.3 2.1 0.07 12.8 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CCF51366.1 - 0.013 14.5 0.0 0.067 12.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CCF51366.1 - 0.091 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Cortex-I_coil PF09304.5 CCF51367.1 - 4e-35 120.1 19.5 4e-35 120.1 13.5 1.9 2 0 0 2 2 2 1 Cortexillin I, coiled coil Spindle_Spc25 PF08234.7 CCF51367.1 - 2.3e-20 72.3 0.0 6.4e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 CCF51367.1 - 0.00095 17.9 13.3 0.0017 17.0 8.9 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4224 PF13986.1 CCF51367.1 - 0.0093 15.4 1.5 0.022 14.2 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4224) DUF1192 PF06698.6 CCF51367.1 - 0.011 15.5 1.6 0.053 13.3 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1515 PF07439.6 CCF51367.1 - 0.035 13.9 0.4 0.035 13.9 0.3 2.5 3 1 1 4 4 3 0 Protein of unknown function (DUF1515) Mnd1 PF03962.10 CCF51367.1 - 0.15 11.7 14.9 0.024 14.2 7.6 1.8 2 0 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 CCF51367.1 - 0.16 9.8 6.0 0.2 9.4 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 CCF51367.1 - 0.21 10.0 13.7 0.018 13.5 6.4 1.4 2 0 0 2 2 2 0 AAA domain TBPIP PF07106.8 CCF51367.1 - 0.64 9.5 19.1 0.088 12.3 7.7 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 CCF51367.1 - 0.74 8.1 11.4 0.12 10.8 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TMPIT PF07851.8 CCF51367.1 - 1.2 8.1 4.3 1.4 7.8 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein ALMT PF11744.3 CCF51367.1 - 1.8 7.1 4.1 2.2 6.8 2.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IncA PF04156.9 CCF51367.1 - 2.1 7.9 22.9 0.25 10.9 12.5 1.8 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 CCF51367.1 - 2.6 6.9 19.5 11 4.8 13.5 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ax_dynein_light PF10211.4 CCF51367.1 - 3 7.6 20.4 4.9 6.9 0.5 2.5 2 1 1 3 3 3 0 Axonemal dynein light chain ERM PF00769.14 CCF51367.1 - 3.1 7.2 22.2 1.8 8.0 13.6 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2937 PF11157.3 CCF51367.1 - 3.3 7.0 6.3 6.2 6.1 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF972 PF06156.8 CCF51367.1 - 4.3 7.7 14.0 0.79 10.1 6.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Filament PF00038.16 CCF51367.1 - 4.3 6.7 20.8 2.1 7.7 12.1 2.0 2 1 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CCF51367.1 - 8.7 6.0 26.8 16 5.2 0.1 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HalX PF08663.5 CCF51367.1 - 9.9 6.2 15.8 8.5 6.4 3.6 3.2 3 0 0 3 3 3 0 HalX domain TPK_catalytic PF04263.11 CCF51368.1 - 7.8e-20 70.6 0.0 1.7e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CCF51368.1 - 3e-18 65.3 0.0 5.1e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Lactamase_B_2 PF12706.2 CCF51368.1 - 3.2e-18 65.9 0.0 7.6e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF51368.1 - 3.1e-12 46.5 0.0 6.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 CCF51368.1 - 0.1 12.1 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease PDEase_II PF02112.10 CCF51368.1 - 0.27 10.1 0.0 0.47 9.3 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Septin PF00735.13 CCF51369.1 - 3.6e-108 360.8 1.1 3.6e-108 360.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCF51369.1 - 3.1e-07 30.3 0.0 6.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF51369.1 - 0.00014 21.3 0.0 0.006 16.0 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCF51369.1 - 0.00015 21.5 6.3 0.0069 16.2 0.1 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCF51369.1 - 0.00098 18.3 0.5 0.0042 16.2 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCF51369.1 - 0.001 19.9 3.9 0.0021 18.8 0.3 2.7 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 CCF51369.1 - 0.0011 19.4 0.4 0.0034 17.8 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein AAA_28 PF13521.1 CCF51369.1 - 0.0013 18.7 4.3 0.013 15.4 0.3 3.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCF51369.1 - 0.0013 18.2 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gasdermin PF04598.7 CCF51369.1 - 0.0022 16.8 1.4 0.0031 16.3 1.0 1.2 1 0 0 1 1 1 1 Gasdermin family AAA_22 PF13401.1 CCF51369.1 - 0.0025 17.9 0.5 0.012 15.7 0.0 2.3 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CCF51369.1 - 0.0028 17.5 0.0 0.0095 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AIG1 PF04548.11 CCF51369.1 - 0.0035 16.4 0.0 0.007 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 CCF51369.1 - 0.0043 15.9 0.2 0.013 14.3 0.1 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MobB PF03205.9 CCF51369.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCF51369.1 - 0.062 13.6 6.8 0.12 12.7 0.7 3.2 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 CCF51369.1 - 0.066 13.5 1.7 0.16 12.2 1.2 2.1 1 1 0 1 1 1 0 ABC transporter Ras PF00071.17 CCF51369.1 - 0.077 12.3 0.4 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.4 CCF51369.1 - 0.082 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCF51369.1 - 0.086 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 CCF51369.1 - 0.086 12.8 0.1 0.086 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Tox-PL-2 PF15643.1 CCF51369.1 - 0.09 12.7 0.1 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Papain fold toxin 2 AAA_19 PF13245.1 CCF51369.1 - 0.1 12.3 0.1 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 CCF51369.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CCF51369.1 - 0.51 10.1 6.4 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CCF51370.1 - 3.9e-20 72.4 0.0 7.8e-20 71.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF51370.1 - 2.4e-10 41.2 0.0 4.5e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCF51370.1 - 7.6e-05 22.7 2.4 0.0011 18.9 1.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCF51370.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 CCF51370.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 CCF51370.1 - 0.015 14.6 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase DUF927 PF06048.6 CCF51370.1 - 0.016 14.4 1.1 0.2 10.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF927) AAA_33 PF13671.1 CCF51370.1 - 0.019 14.8 1.0 0.56 10.0 0.7 2.5 1 1 0 1 1 1 0 AAA domain ADK PF00406.17 CCF51370.1 - 0.02 14.7 0.4 0.67 9.8 0.1 2.4 2 1 0 2 2 2 0 Adenylate kinase AAA_22 PF13401.1 CCF51370.1 - 0.022 14.9 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCF51370.1 - 0.03 14.0 0.1 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CCF51370.1 - 0.043 13.7 0.2 0.079 12.9 0.1 1.6 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 CCF51370.1 - 0.044 12.8 0.1 0.38 9.8 0.0 2.0 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.10 CCF51370.1 - 0.047 13.3 1.3 0.14 11.9 0.1 2.2 3 0 0 3 3 3 0 NTPase SKI PF01202.17 CCF51370.1 - 0.07 12.9 0.3 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_14 PF13173.1 CCF51370.1 - 0.074 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CCF51370.1 - 0.084 11.6 0.1 0.19 10.4 0.1 1.5 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 CCF51370.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 CCF51370.1 - 0.22 10.4 1.1 0.27 10.0 0.3 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein NMO PF03060.10 CCF51371.1 - 3.6e-70 236.7 0.4 4.2e-70 236.4 0.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCF51371.1 - 1.4e-08 34.0 0.8 3.3e-08 32.8 0.5 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CCF51371.1 - 0.0084 14.9 3.1 0.014 14.2 2.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.12 CCF51371.1 - 0.026 13.7 1.9 0.65 9.1 0.1 3.0 3 0 0 3 3 3 0 PcrB family LSM PF01423.17 CCF51372.1 - 7.5e-08 31.8 0.0 9.6e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCF51372.1 - 0.00041 20.2 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain ABC_tran PF00005.22 CCF51374.1 - 1.6e-48 164.4 0.2 2.2e-23 83.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 CCF51374.1 - 1.6e-21 76.7 28.6 1.1e-12 47.6 4.5 2.6 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CCF51374.1 - 9.7e-15 55.2 2.6 1.2e-05 25.4 0.0 4.4 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 CCF51374.1 - 6.6e-06 25.5 0.0 0.13 11.4 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF51374.1 - 0.00011 21.6 0.5 0.013 14.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 CCF51374.1 - 0.04 13.3 3.0 4 6.8 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 CCF51374.1 - 0.049 13.5 0.1 2.5 8.0 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CCF51374.1 - 0.15 12.3 1.5 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain RVT_2 PF07727.9 CCF51376.1 - 2e-44 151.4 0.1 2.2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF51376.1 - 0.097 12.0 0.1 0.21 10.9 0.1 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Pox_A12 PF04651.8 CCF51377.1 - 0.044 13.9 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein YqfQ PF14181.1 CCF51380.1 - 8.5 6.3 9.1 0.88 9.5 3.1 1.7 2 0 0 2 2 2 0 YqfQ-like protein Pkr1 PF08636.5 CCF51381.1 - 2.9e-16 59.2 7.2 3.5e-16 59.0 5.0 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2628 PF10947.3 CCF51381.1 - 0.0032 17.2 0.8 0.0036 17.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2628) PRA1 PF03208.14 CCF51381.1 - 0.011 15.1 1.7 0.014 14.7 1.2 1.2 1 0 0 1 1 1 0 PRA1 family protein UPF0154 PF03672.8 CCF51381.1 - 0.13 11.8 1.6 1 9.0 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) DLIC PF05783.6 CCF51382.1 - 5.3e-46 157.2 17.3 1.5e-25 89.8 0.0 7.2 4 3 1 7 7 7 6 Dynein light intermediate chain (DLIC) Miro PF08477.8 CCF51382.1 - 0.01 16.3 0.1 0.1 13.0 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 CCF51382.1 - 0.011 15.7 1.8 0.011 15.7 1.2 3.2 3 1 1 4 4 4 0 AAA ATPase domain MMR_HSR1 PF01926.18 CCF51382.1 - 0.045 13.6 0.2 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.18 CCF51382.1 - 0.1 11.3 0.4 0.2 10.3 0.1 1.5 2 0 0 2 2 2 0 MCM2/3/5 family G-alpha PF00503.15 CCF51382.1 - 0.27 9.8 2.6 0.41 9.2 0.6 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF442 PF04273.8 CCF51382.1 - 1.6 8.6 9.8 0.34 10.7 0.1 3.0 3 0 0 3 3 3 0 Putative phosphatase (DUF442) IPP-2 PF04979.9 CCF51383.1 - 2.5e-13 50.3 6.1 7.4e-06 26.2 3.6 2.4 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Corona_nucleoca PF00937.13 CCF51383.1 - 0.034 13.0 5.7 0.05 12.5 3.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SOG2 PF10428.4 CCF51384.1 - 0.47 9.0 10.0 0.75 8.3 6.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein LNS2 PF08235.8 CCF51385.1 - 9.8e-68 226.6 0.0 9e-54 181.2 0.0 2.6 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCF51385.1 - 4.6e-27 93.8 0.1 1.7e-17 63.0 0.0 2.5 2 0 0 2 2 2 2 lipin, N-terminal conserved region CN_hydrolase PF00795.17 CCF51386.1 - 1.3e-13 50.7 0.1 3.9e-12 45.9 0.1 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase YlbD_coat PF14071.1 CCF51386.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative coat protein Peptidase_S10 PF00450.17 CCF51387.1 - 2.8e-101 339.7 0.0 3.5e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 CCF51387.1 - 0.027 14.2 0.0 0.14 11.9 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Myb_DNA-bind_6 PF13921.1 CCF51388.1 - 1.7e-21 76.0 0.8 2.7e-07 30.6 0.2 5.7 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCF51388.1 - 3e-21 75.2 7.5 1.7e-09 37.5 0.1 6.2 6 1 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CCF51388.1 - 0.00023 21.2 0.7 11 6.2 0.1 4.1 4 0 0 4 4 4 3 Myb/SANT-like DNA-binding domain TAF1D PF15333.1 CCF51388.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D Ribosomal_S7 PF00177.16 CCF51389.1 - 4.3e-36 123.7 0.1 8.2e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ebp2 PF05890.7 CCF51389.1 - 0.2 10.9 2.1 0.29 10.3 0.3 1.9 2 0 0 2 2 2 0 Eukaryotic rRNA processing protein EBP2 SUR7 PF06687.7 CCF51390.1 - 1.3e-19 70.5 5.2 2e-19 69.9 3.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCF51390.1 - 0.0008 19.1 3.6 0.0012 18.5 2.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction RseC_MucC PF04246.7 CCF51390.1 - 0.027 14.0 0.6 0.046 13.2 0.4 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF2207 PF09972.4 CCF51390.1 - 0.043 12.4 0.4 0.08 11.5 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2628 PF10947.3 CCF51390.1 - 0.34 10.7 4.0 3.1 7.6 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF2254 PF10011.4 CCF51390.1 - 0.6 8.5 5.8 0.17 10.2 1.4 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) ABC2_membrane_2 PF12679.2 CCF51390.1 - 0.77 8.5 8.7 0.15 10.8 3.1 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Phosphodiest PF01663.17 CCF51391.1 - 2.4e-10 40.2 0.2 4.2e-10 39.4 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCF51391.1 - 0.00069 19.0 1.2 0.0011 18.3 0.9 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily E1-E2_ATPase PF00122.15 CCF51392.1 - 9.2e-58 194.9 0.1 9.2e-58 194.9 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF51392.1 - 8.3e-46 155.8 10.0 8.3e-46 155.8 6.9 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF51392.1 - 6.2e-26 92.1 0.0 3.7e-25 89.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF51392.1 - 1.2e-17 63.6 0.1 2.5e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCF51392.1 - 1.1e-13 51.7 0.0 1.1e-12 48.5 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF51392.1 - 3.9e-07 29.4 0.8 1.2e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCF51392.1 - 0.00054 19.6 0.2 0.012 15.1 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1373 PF07117.6 CCF51392.1 - 0.036 13.7 0.7 0.43 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) Myco_arth_vir_N PF09610.5 CCF51394.1 - 0.41 10.6 2.1 1.2 9.1 1.4 1.9 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) BSP_II PF05432.6 CCF51395.1 - 0.002 17.4 6.4 0.0022 17.3 4.4 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 CCF51395.1 - 0.0037 16.7 5.9 0.004 16.6 4.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 CCF51395.1 - 0.016 15.4 6.2 0.022 15.0 4.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BUD22 PF09073.5 CCF51395.1 - 0.029 13.4 5.6 0.033 13.2 3.9 1.0 1 0 0 1 1 1 0 BUD22 DGF-1_C PF11040.3 CCF51395.1 - 0.038 13.8 2.2 0.046 13.6 1.0 1.5 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Myc_N PF01056.13 CCF51395.1 - 0.042 13.0 5.9 0.042 13.0 4.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 CCF51395.1 - 0.056 13.2 3.1 0.064 13.0 2.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 CCF51395.1 - 0.088 12.9 6.4 0.11 12.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3899 PF13038.1 CCF51395.1 - 0.093 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) RNA_pol_3_Rpc31 PF11705.3 CCF51395.1 - 0.13 12.1 8.0 0.16 11.9 5.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 CCF51395.1 - 0.14 11.8 5.4 0.16 11.6 3.8 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 CCF51395.1 - 0.14 11.3 1.2 0.15 11.3 0.8 1.1 1 0 0 1 1 1 0 NOA36 protein GEMIN8 PF15348.1 CCF51395.1 - 0.15 12.1 4.4 0.15 12.0 3.0 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF1510 PF07423.6 CCF51395.1 - 0.15 11.4 5.3 0.17 11.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 CCF51395.1 - 0.2 9.4 2.6 0.2 9.4 1.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Saw1 PF11561.3 CCF51395.1 - 0.21 10.9 2.0 0.21 10.9 1.4 1.1 1 0 0 1 1 1 0 Single strand annealing-weakened 1 EBV-NA3 PF05009.7 CCF51395.1 - 0.21 10.8 2.6 0.22 10.7 1.8 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DUF3537 PF12056.3 CCF51395.1 - 0.33 9.6 1.1 0.39 9.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FLO_LFY PF01698.11 CCF51395.1 - 0.34 9.7 3.4 0.37 9.5 2.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein VID27 PF08553.5 CCF51395.1 - 0.37 8.9 4.8 0.37 8.9 3.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cut8_N PF14482.1 CCF51395.1 - 0.48 10.4 8.2 20 5.2 5.7 2.2 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Pox_Ag35 PF03286.9 CCF51395.1 - 0.48 9.9 8.4 0.55 9.7 5.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PGA2 PF07543.7 CCF51395.1 - 0.51 10.1 7.9 0.63 9.8 5.5 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Radial_spoke PF04712.7 CCF51395.1 - 0.58 8.8 7.0 0.62 8.7 4.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein MscS_TM PF12794.2 CCF51395.1 - 0.6 8.6 2.3 0.75 8.3 1.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SAPS PF04499.10 CCF51395.1 - 0.77 8.3 4.0 0.86 8.1 2.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDV3 PF15359.1 CCF51395.1 - 1.2 9.2 9.2 1.9 8.5 6.4 1.3 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 CDC45 PF02724.9 CCF51395.1 - 1.3 6.9 5.0 1.3 6.9 3.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 CCF51395.1 - 2.3 7.3 7.3 2.9 7.0 5.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DDHD PF02862.12 CCF51395.1 - 2.8 7.6 4.9 3.1 7.5 3.4 1.1 1 0 0 1 1 1 0 DDHD domain Pox_RNA_Pol_19 PF05320.7 CCF51395.1 - 7 6.3 8.7 8.4 6.1 5.7 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit MFS_1 PF07690.11 CCF51396.1 - 3.4e-32 111.5 26.1 4.8e-32 111.0 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TIP120 PF08623.5 CCF51397.1 - 4.8e-52 175.9 5.9 5.8e-52 175.6 0.2 3.5 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 CCF51397.1 - 1.9e-19 69.7 35.4 4.1e-05 23.7 0.1 10.5 8 5 4 12 12 12 8 HEAT repeats HEAT PF02985.17 CCF51397.1 - 2.7e-14 51.9 36.0 0.49 10.6 0.0 14.7 15 0 0 15 15 15 5 HEAT repeat HEAT_EZ PF13513.1 CCF51397.1 - 9.1e-14 51.4 42.4 0.0016 18.8 0.0 12.8 11 2 4 15 15 15 6 HEAT-like repeat Cnd1 PF12717.2 CCF51397.1 - 8.1e-05 22.5 16.2 0.057 13.2 0.0 5.7 4 3 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 CCF51397.1 - 0.0018 18.1 4.9 1.8 8.5 0.0 5.9 6 1 2 8 8 8 1 UME (NUC010) domain Cohesin_HEAT PF12765.2 CCF51397.1 - 0.0024 17.7 0.1 0.017 15.0 0.1 2.6 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion DUF2738 PF10927.3 CCF51397.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Arm PF00514.18 CCF51397.1 - 0.15 11.9 6.5 1.2e+02 2.6 0.0 6.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat PCI PF01399.22 CCF51398.1 - 1.6e-05 25.1 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 CCF51398.1 - 2.4 8.3 6.2 0.49 10.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MutL_C PF08676.6 CCF51401.1 - 2.3e-09 37.0 0.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 MutL C terminal dimerisation domain Linker_histone PF00538.14 CCF51402.1 - 2.6e-11 43.4 0.1 6.4e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.6 CCF51402.1 - 0.00096 19.0 72.6 0.0027 17.6 39.2 2.2 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Menin PF05053.8 CCF51402.1 - 2.5 6.1 8.6 2.8 6.0 5.9 1.1 1 0 0 1 1 1 0 Menin Herpes_UL17 PF04559.7 CCF51402.1 - 5.5 5.4 7.9 6.5 5.2 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein Adap_comp_sub PF00928.16 CCF51403.1 - 9.6e-92 306.7 0.0 1.4e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCF51403.1 - 5.8e-07 29.3 0.2 9.8e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 CCF51403.1 - 0.033 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain PA_decarbox PF05870.6 CCF51404.1 - 1.8e-10 40.4 0.1 2.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) ParA PF10609.4 CCF51405.1 - 6e-33 112.5 0.0 1e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCF51405.1 - 3.2e-10 39.7 0.6 4e-09 36.1 0.4 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CCF51405.1 - 8.3e-07 29.0 0.0 6.2e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 CCF51405.1 - 8.9e-05 21.6 4.7 0.00011 21.3 0.2 2.7 3 1 1 4 4 4 1 Anion-transporting ATPase AAA_25 PF13481.1 CCF51405.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 CCF51405.1 - 0.0041 16.2 0.0 0.013 14.5 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ zf-C4_ClpX PF06689.8 CCF51405.1 - 0.0081 15.6 0.3 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 ClpX C4-type zinc finger Cache_3 PF14827.1 CCF51405.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase AAA_26 PF13500.1 CCF51405.1 - 0.05 13.2 0.1 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCF51405.1 - 0.061 12.5 0.2 0.13 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3665 PF12427.3 CCF51406.1 - 0.6 9.5 4.8 1.5 8.2 3.3 1.6 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase EMP24_GP25L PF01105.19 CCF51408.1 - 1.1e-48 165.3 0.0 1.3e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Voltage_CLC PF00654.15 CCF51409.1 - 5.4e-92 308.5 27.8 1e-91 307.6 19.3 1.5 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 CCF51409.1 - 1.1e-08 34.6 0.0 8.7e-07 28.6 0.0 2.6 2 0 0 2 2 2 1 CBS domain Pro_isomerase PF00160.16 CCF51410.1 - 3e-28 98.9 0.0 5.2e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CCF51410.1 - 1.8e-16 59.5 0.0 4.2e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51410.1 - 1.5e-11 44.1 0.0 3.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51410.1 - 7.4e-08 32.1 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Oxysterol_BP PF01237.13 CCF51411.1 - 2.4e-83 279.5 0.0 3.1e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Pkinase PF00069.20 CCF51412.1 - 1.5e-57 194.7 0.0 6.9e-57 192.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51412.1 - 1.3e-26 93.2 0.0 2.3e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF51412.1 - 1.1e-06 27.8 0.0 2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF51412.1 - 0.0054 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L2 PF00181.18 CCF51412.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain Seadorna_VP7 PF07387.6 CCF51412.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pro_isomerase PF00160.16 CCF51413.1 - 1.1e-33 116.6 0.0 1.2e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PCI PF01399.22 CCF51414.1 - 0.00063 20.0 0.1 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Hrs_helical PF12210.3 CCF51414.1 - 0.037 14.2 1.1 0.078 13.2 0.6 1.7 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF148 PF02520.12 CCF51414.1 - 0.16 11.8 4.6 0.25 11.1 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 FlxA PF14282.1 CCF51414.1 - 0.25 11.2 15.3 0.08 12.8 8.4 1.8 2 0 0 2 2 2 0 FlxA-like protein Muted PF14942.1 CCF51414.1 - 0.35 10.7 3.8 0.63 9.9 2.6 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Choline_transpo PF04515.7 CCF51415.1 - 5.6e-38 130.5 10.4 6.1e-25 87.6 0.0 2.3 2 0 0 2 2 2 2 Plasma-membrane choline transporter GrpE PF01025.14 CCF51416.1 - 3.2e-43 147.1 0.4 4.4e-43 146.7 0.3 1.2 1 0 0 1 1 1 1 GrpE DUF4201 PF13870.1 CCF51416.1 - 0.013 14.9 0.5 0.022 14.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.6 CCF51416.1 - 0.037 14.4 1.2 0.96 9.8 1.1 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cluap1 PF10234.4 CCF51416.1 - 0.08 12.1 0.9 0.15 11.2 0.6 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Bap31 PF05529.7 CCF51416.1 - 4.2 6.7 4.8 6.1 6.2 3.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RRM_1 PF00076.17 CCF51417.1 - 7.7e-78 256.1 0.5 8.3e-20 70.1 0.2 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51417.1 - 7.2e-56 186.0 0.2 2.1e-15 56.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51417.1 - 2.2e-46 155.5 0.1 2.3e-11 43.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCF51417.1 - 6.9e-30 102.5 3.0 3.5e-29 100.2 1.8 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CCF51417.1 - 0.00037 20.3 3.4 0.28 11.0 0.7 3.4 4 0 0 4 4 4 2 RNA binding motif Limkain-b1 PF11608.3 CCF51417.1 - 0.00054 19.6 1.8 0.15 11.8 0.1 3.6 4 0 0 4 4 4 1 Limkain b1 CbiG_mid PF11761.3 CCF51417.1 - 0.00086 19.4 0.1 4.3 7.6 0.0 3.5 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 CCF51417.1 - 0.0046 16.7 0.2 8.3 6.2 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 CCF51417.1 - 0.039 13.5 0.3 0.4 10.2 0.1 2.6 3 0 0 3 3 3 0 Calcipressin OB_RNB PF08206.6 CCF51417.1 - 0.083 12.3 1.7 5.4 6.6 0.3 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain KH_1 PF00013.24 CCF51418.1 - 0.00034 20.2 1.1 0.00074 19.1 0.8 1.5 1 0 0 1 1 1 1 KH domain DUF4357 PF14267.1 CCF51418.1 - 1.9 8.1 6.5 4.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) RAP1 PF07218.6 CCF51418.1 - 5.2 5.0 10.1 12 3.8 7.0 1.6 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_22 PF13401.1 CCF51419.1 - 3.3e-17 62.8 0.3 2.7e-16 59.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CCF51419.1 - 2.1e-09 37.6 0.0 4.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCF51419.1 - 2.6e-07 30.4 0.0 7.4e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CCF51419.1 - 1.6e-06 28.2 1.6 1.6e-06 28.2 1.1 3.5 2 2 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CCF51419.1 - 0.0001 21.3 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 CCF51419.1 - 0.0013 18.4 0.0 0.01 15.5 0.0 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 CCF51419.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CCF51419.1 - 0.052 13.2 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 NTPase WD40 PF00400.27 CCF51421.1 - 5.5e-46 152.8 10.1 7.6e-10 38.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCF51421.1 - 1.6e-09 36.5 2.3 0.00056 18.1 0.0 4.5 3 2 2 5 5 5 3 Nucleoporin Nup120/160 DUF869 PF05911.6 CCF51421.1 - 0.014 13.7 0.5 0.019 13.2 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) EzrA PF06160.7 CCF51421.1 - 0.014 13.6 0.1 0.019 13.1 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Chs3p PF12271.3 CCF51422.1 - 8.6e-112 372.8 18.4 1e-111 372.6 12.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Asn_synthase PF00733.16 CCF51423.1 - 6.5e-48 163.4 0.0 1.5e-47 162.2 0.0 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCF51423.1 - 7.2e-11 41.8 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCF51423.1 - 1.8e-08 34.4 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Rho_N PF07498.7 CCF51423.1 - 0.047 13.4 0.2 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain RabGAP-TBC PF00566.13 CCF51424.1 - 5.2e-59 199.3 0.5 8.2e-59 198.6 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_topoisoIV PF00521.15 CCF51425.1 - 1.6e-128 429.2 0.0 2.8e-128 428.4 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCF51425.1 - 4.8e-36 123.5 0.9 1.3e-35 122.1 0.6 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCF51425.1 - 1.5e-14 53.7 0.0 6e-14 51.8 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCF51425.1 - 3.9e-09 36.2 0.0 9.9e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase tRNA-synt_2b PF00587.20 CCF51426.1 - 6.1e-21 74.7 0.0 8.1e-17 61.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) FLILHELTA PF10306.4 CCF51426.1 - 5.9e-19 67.8 0.0 1.5e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Nup54 PF13874.1 CCF51426.1 - 0.0058 16.2 2.6 0.0058 16.2 1.8 2.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF1279 PF06916.8 CCF51426.1 - 0.1 12.9 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Linocin_M18 PF04454.7 CCF51426.1 - 0.14 11.0 3.0 0.22 10.4 2.1 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Seryl_tRNA_N PF02403.17 CCF51426.1 - 0.32 11.0 18.4 0.14 12.2 2.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain EMP24_GP25L PF01105.19 CCF51426.1 - 0.61 9.7 4.1 1.3 8.7 2.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD GAGA_bind PF06217.7 CCF51426.1 - 1.4 8.7 10.0 2.5 7.9 7.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Uds1 PF15456.1 CCF51426.1 - 6.8 6.7 19.9 1.6 8.7 10.2 2.5 1 1 1 2 2 2 0 Up-regulated During Septation Band_7 PF01145.20 CCF51427.1 - 9.1e-25 87.5 4.3 1.1e-24 87.2 2.2 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family PNP_UDP_1 PF01048.15 CCF51428.1 - 2.3e-25 88.9 0.0 3.1e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Caleosin PF05042.8 CCF51429.1 - 0.043 13.3 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 Caleosin related protein Uteroglobin PF01099.12 CCF51429.1 - 0.34 10.7 2.8 4.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Uteroglobin family SAC3_GANP PF03399.11 CCF51430.1 - 5.9e-56 189.2 0.0 2.1e-55 187.4 0.0 1.9 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family MFS_1 PF07690.11 CCF51431.1 - 4.1e-30 104.6 33.7 1.1e-21 76.9 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CDP-OH_P_tran_2 PF08009.6 CCF51431.1 - 0.039 13.6 3.8 0.074 12.7 0.7 2.8 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 ApoLp-III PF07464.6 CCF51432.1 - 0.005 16.8 14.1 0.087 12.8 2.9 3.2 3 0 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Rota_NS26 PF01525.11 CCF51432.1 - 0.1 12.3 2.7 0.11 12.2 0.4 2.1 2 0 0 2 2 2 0 Rotavirus NS26 Atg14 PF10186.4 CCF51432.1 - 4.7 6.0 23.2 3.4 6.5 6.3 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 CCF51433.1 - 2.2e-10 40.3 12.6 4.1e-10 39.4 8.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCF51433.1 - 1.1e-07 31.5 9.9 1.7e-07 30.9 6.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.13 CCF51433.1 - 0.21 11.5 0.7 0.44 10.5 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Spt5_N PF11942.3 CCF51433.1 - 5.4 7.6 13.0 1.7 9.3 6.4 2.1 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_S8e PF01201.17 CCF51436.1 - 4.9e-50 169.0 2.2 5.9e-50 168.8 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e tRNA-synt_1 PF00133.17 CCF51437.1 - 1.1e-216 720.5 0.0 4.9e-216 718.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCF51437.1 - 5e-39 133.4 0.3 9.8e-39 132.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCF51437.1 - 1.1e-17 63.8 0.1 9.3e-09 34.4 0.0 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCF51437.1 - 1.8e-12 46.9 0.1 1.2e-07 31.2 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CCF51437.1 - 0.0065 16.5 3.6 0.04 13.9 2.5 2.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CCF51437.1 - 0.026 13.3 0.0 0.31 9.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 CCF51437.1 - 0.036 12.7 0.2 2.6 6.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF3502 PF12010.3 CCF51437.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) tRNA-synt_1e PF01406.14 CCF51437.1 - 0.069 12.2 0.0 0.99 8.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Methyltransf_23 PF13489.1 CCF51438.1 - 3.3e-09 36.6 0.0 6.8e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF51438.1 - 2.4e-05 24.7 0.0 5.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF51438.1 - 0.00024 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 CCF51438.1 - 0.00041 19.9 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 CCF51438.1 - 0.00042 19.9 0.0 0.0021 17.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF51438.1 - 0.00059 20.3 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCF51438.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Fungal_trans PF04082.13 CCF51439.1 - 4.3e-13 48.7 0.0 9.3e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF51439.1 - 0.00012 21.9 14.8 0.00021 21.1 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 CCF51440.1 - 4.3e-42 144.3 0.0 6.8e-42 143.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCF51440.1 - 0.0012 17.2 0.0 0.0022 16.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCF51440.1 - 0.0095 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pectinesterase PF01095.14 CCF51441.1 - 2e-29 102.1 0.2 2.7e-25 88.5 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase NAD_binding_10 PF13460.1 CCF51442.1 - 3.9e-23 82.3 0.0 5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCF51442.1 - 2.3e-05 23.9 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CCF51442.1 - 0.0039 16.4 0.0 0.0072 15.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 CCF51442.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein HAD_2 PF13419.1 CCF51443.1 - 2.5e-26 92.9 0.5 8.7e-26 91.2 0.4 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 CCF51443.1 - 1.1e-16 59.9 0.1 2.7e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 CCF51443.1 - 1.9e-13 49.9 0.2 3.8e-13 48.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF51443.1 - 3.8e-10 39.1 0.2 1.1e-09 37.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain Hydrolase_like PF13242.1 CCF51443.1 - 0.0074 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Nup160 PF11715.3 CCF51443.1 - 0.015 13.5 0.6 0.052 11.6 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCF51443.1 - 0.098 12.9 1.1 4.7 7.6 0.1 3.8 3 1 1 4 4 4 0 PQQ-like domain TB2_DP1_HVA22 PF03134.14 CCF51444.1 - 3.2e-33 113.3 7.3 4.7e-33 112.8 5.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PSI_PsaE PF02427.12 CCF51444.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE CENP-I PF07778.6 CCF51445.1 - 6.6e-20 70.7 0.3 3.9e-17 61.6 0.0 3.4 3 1 0 3 3 3 1 Mis6 AA_permease_2 PF13520.1 CCF51447.1 - 3.8e-53 180.5 58.3 4.7e-53 180.2 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF51447.1 - 6.1e-19 67.7 51.5 8.4e-19 67.2 35.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 CCF51448.1 - 3.2e-178 592.8 0.2 3.6e-178 592.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF51448.1 - 2.7e-08 32.9 0.0 4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Cu_amine_oxid PF01179.15 CCF51449.1 - 2.1e-159 530.7 0.3 2.5e-159 530.4 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 CCF51449.1 - 1.2e-13 50.9 0.0 2.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 CCF51449.1 - 2.1e-05 24.4 0.1 7.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Zn_clus PF00172.13 CCF51450.1 - 0.00022 21.0 10.1 0.00035 20.4 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain QCR10 PF09796.4 CCF51451.1 - 1.3e-24 85.6 0.7 1.5e-24 85.3 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CCF51451.1 - 0.026 14.2 2.4 0.034 13.8 1.6 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Gln-synt_C PF00120.19 CCF51452.1 - 1.2e-60 204.9 0.0 1.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCF51452.1 - 2e-18 65.7 0.0 3.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF676 PF05057.9 CCF51453.1 - 4.9e-06 25.9 0.0 9.5e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCF51453.1 - 0.0076 15.8 0.1 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ribosomal_L3 PF00297.17 CCF51454.1 - 8.5e-33 113.8 3.1 1.6e-32 112.9 2.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L3 RVT_2 PF07727.9 CCF51455.1 - 1.3e-12 47.2 0.2 1.6e-12 46.9 0.2 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DXP_redisom_C PF08436.7 CCF51456.1 - 0.11 12.4 0.2 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal rve PF00665.21 CCF51457.1 - 1.5e-08 34.7 0.0 4.1e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF51457.1 - 1.4e-06 27.8 0.3 3.3e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Pam16 PF03656.8 CCF51458.1 - 5.1e-19 68.3 0.8 4.7e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Pam16 tRNA-synt_1g PF09334.6 CCF51459.1 - 6.9e-143 475.9 0.0 1.2e-142 475.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCF51459.1 - 7.2e-09 34.1 0.1 0.00033 18.8 0.0 3.8 2 2 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCF51459.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA IncA PF04156.9 CCF51459.1 - 0.044 13.3 8.4 0.07 12.7 5.8 1.2 1 0 0 1 1 1 0 IncA protein DZR PF12773.2 CCF51459.1 - 0.69 9.7 8.6 4.6 7.1 6.0 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF16 PF01519.11 CCF51459.1 - 1.5 9.0 7.0 3 8.1 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 F-box-like PF12937.2 CCF51460.1 - 0.068 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 F-box-like Ribosomal_L14 PF00238.14 CCF51461.1 - 2.6e-34 117.6 0.0 2.9e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e F-box-like PF12937.2 CCF51462.1 - 0.00066 19.3 0.3 0.002 17.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF51462.1 - 0.0084 15.7 0.1 0.032 13.9 0.1 1.9 1 1 0 1 1 1 1 F-box domain Myc_N PF01056.13 CCF51462.1 - 0.05 12.7 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RVT_1 PF00078.22 CCF51464.1 - 1.7e-20 73.3 0.2 4.3e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF51464.1 - 2.5e-20 72.7 0.0 2.2e-19 69.7 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CCF51464.1 - 7.1e-12 44.8 0.0 1.5e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 CCF51464.1 - 4e-10 39.6 0.3 2.5e-09 37.1 0.1 2.5 2 0 0 2 2 2 1 Retrotransposon gag protein gag-asp_proteas PF13975.1 CCF51464.1 - 8.2e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCF51464.1 - 4.1e-05 23.5 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CCF51464.1 - 0.00063 20.1 0.0 0.0016 18.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.5 CCF51464.1 - 0.27 10.6 0.0 0.72 9.3 0.0 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger zf-C2H2_4 PF13894.1 CCF51467.1 - 0.0044 17.2 14.6 0.026 14.8 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF51467.1 - 0.13 12.6 1.8 1.3 9.4 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 CCF51467.1 - 1.2 9.6 16.8 0.23 11.8 0.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type OTCace PF00185.19 CCF51468.1 - 7.1e-41 139.7 0.0 1.1e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CCF51468.1 - 8.2e-41 138.9 0.1 1.4e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Aminotran_1_2 PF00155.16 CCF51469.1 - 1.6e-18 66.7 0.0 2e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCF51469.1 - 4.4e-05 22.2 0.0 7.1e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.16 CCF51469.1 - 0.16 10.8 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III BAR_2 PF10455.4 CCF51470.1 - 1.2e-46 158.9 0.3 2.4e-46 157.9 0.2 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CCF51470.1 - 1.1e-20 74.0 4.4 2.9e-16 59.6 1.6 2.1 2 0 0 2 2 2 2 BAR domain Phasin PF05597.6 CCF51470.1 - 0.012 15.4 4.1 0.038 13.7 0.0 2.9 3 1 0 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) 14-3-3 PF00244.15 CCF51470.1 - 0.015 14.4 0.6 0.023 13.7 0.4 1.2 1 0 0 1 1 1 0 14-3-3 protein ATG16 PF08614.6 CCF51470.1 - 0.068 12.9 9.5 0.2 11.4 3.0 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Telethonin PF09470.5 CCF51470.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Telethonin protein Uds1 PF15456.1 CCF51470.1 - 0.086 12.8 8.8 0.72 9.8 0.0 2.8 3 0 0 3 3 3 0 Up-regulated During Septation DUF4615 PF15393.1 CCF51470.1 - 0.087 13.0 0.3 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) DUF148 PF02520.12 CCF51470.1 - 0.12 12.1 9.0 2.7 7.8 3.1 3.3 2 2 0 2 2 2 0 Domain of unknown function DUF148 DUF2205 PF10224.4 CCF51470.1 - 0.12 11.9 0.8 0.48 10.0 0.0 2.4 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Tropomyosin_1 PF12718.2 CCF51470.1 - 0.17 11.7 4.9 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.17 CCF51470.1 - 0.68 9.9 6.4 31 4.6 0.0 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.7 CCF51470.1 - 0.79 9.3 5.5 0.37 10.4 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) bZIP_1 PF00170.16 CCF51470.1 - 0.89 9.5 3.5 2 8.4 0.0 2.8 3 0 0 3 3 2 0 bZIP transcription factor Spectrin PF00435.16 CCF51470.1 - 1.9 8.8 8.1 6.9 7.0 0.2 3.0 2 2 0 2 2 2 0 Spectrin repeat Atg14 PF10186.4 CCF51470.1 - 2 7.2 5.4 0.98 8.3 1.4 2.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 CCF51470.1 - 2.3 7.4 11.1 8.7 5.5 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6 PF04111.7 CCF51470.1 - 7.1 5.5 9.4 15 4.5 4.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CCF51470.1 - 7.2 6.5 13.5 9 6.1 0.1 4.1 4 1 1 5 5 4 0 TATA element modulatory factor 1 DNA binding DUF4451 PF14616.1 CCF51472.1 - 2.2e-32 111.4 0.7 4e-32 110.5 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) HJURP_C PF12347.3 CCF51472.1 - 0.019 14.4 0.0 0.07 12.7 0.0 1.9 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat CMS1 PF14617.1 CCF51473.1 - 2.6e-50 170.8 2.1 1.4e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit CDC45 PF02724.9 CCF51473.1 - 0.59 8.1 4.1 6.8 4.6 2.7 2.0 2 0 0 2 2 2 0 CDC45-like protein ING PF12998.2 CCF51474.1 - 6.2e-10 39.2 1.0 8.4e-10 38.8 0.7 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCF51474.1 - 8e-09 35.0 7.2 1.2e-08 34.4 5.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF51474.1 - 0.036 13.3 2.2 0.064 12.5 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Med4 PF10018.4 CCF51474.1 - 0.061 12.7 0.3 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 CCF51474.1 - 0.14 11.9 0.1 2.9 7.7 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CPSase_L_D2 PF02786.12 CCF51475.1 - 7.5e-113 374.9 0.1 1.8e-82 275.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 CCF51475.1 - 4.9e-46 156.5 0.0 2.2e-45 154.4 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CCF51475.1 - 1.6e-44 150.9 0.0 3.9e-44 149.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 CCF51475.1 - 2.8e-44 149.7 0.0 6e-44 148.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 CCF51475.1 - 1.1e-42 144.7 0.2 2.1e-42 143.7 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CCF51475.1 - 1.6e-41 140.8 0.0 6.5e-20 71.2 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CCF51475.1 - 1.6e-36 125.7 0.2 2.7e-21 76.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 CCF51475.1 - 1.7e-34 118.9 0.0 4.2e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 CCF51475.1 - 4.1e-23 81.6 0.1 5.5e-12 45.0 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCF51475.1 - 1e-17 64.0 0.0 3.3e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCF51475.1 - 5.1e-16 58.6 0.0 2e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CCF51475.1 - 6.9e-11 41.9 0.0 2.3e-10 40.2 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Peptidase_C26 PF07722.8 CCF51475.1 - 8.4e-07 28.6 0.1 2.9e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CCF51475.1 - 1.3e-05 25.1 0.1 0.084 12.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 CCF51475.1 - 0.0011 18.5 0.0 0.094 12.2 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 CCF51475.1 - 0.0021 17.5 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CRAL_TRIO PF00650.15 CCF51476.1 - 1.5e-25 89.5 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF51476.1 - 6.1e-05 23.0 0.1 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCF51476.1 - 0.0035 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NADHdh_A3 PF14987.1 CCF51477.1 - 0.016 15.0 0.2 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF1223 PF06764.6 CCF51478.1 - 4.7 6.9 8.7 0.22 11.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1223) ADH_zinc_N PF00107.21 CCF51479.1 - 1.6e-24 85.9 0.0 3.5e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF51479.1 - 1e-05 26.4 0.0 0.00013 22.8 0.0 2.6 2 2 0 2 2 2 1 Zinc-binding dehydrogenase MIF4G PF02854.14 CCF51480.1 - 1.7e-49 168.0 0.0 7.9e-27 94.0 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 CCF51480.1 - 3.2e-14 53.0 0.5 3.2e-14 53.0 0.3 4.4 4 1 1 5 5 5 2 Up-frameshift suppressor 2 RNA_pol_A_bac PF01000.21 CCF51481.1 - 1.5e-27 95.9 0.0 5.1e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCF51481.1 - 5.3e-14 51.0 0.0 7.3e-14 50.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 CCF51481.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 GMC_oxred_N PF00732.14 CCF51483.1 - 1.3e-55 188.6 1.4 1.6e-53 181.7 1.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF51483.1 - 1.7e-28 99.7 0.0 4e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCF51483.1 - 7.3e-10 38.2 0.2 0.00041 19.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 CCF51483.1 - 1.4e-06 27.4 0.3 0.0012 17.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCF51483.1 - 1.9e-06 28.0 0.3 0.026 14.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF51483.1 - 5.4e-06 26.3 0.1 3e-05 23.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCF51483.1 - 0.00013 21.0 0.1 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CCF51483.1 - 0.00015 21.7 0.3 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF51483.1 - 0.006 15.1 0.4 0.15 10.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 CCF51483.1 - 0.024 14.4 0.0 0.089 12.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 CCF51483.1 - 0.024 13.7 0.4 0.063 12.3 0.3 1.6 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 CCF51483.1 - 0.047 12.5 0.2 4.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Nop14 PF04147.7 CCF51484.1 - 5.4 4.8 28.2 6.1 4.6 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4385 PF14328.1 CCF51485.1 - 4.2e-55 185.6 0.3 4.2e-55 185.6 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4385) DTHCT PF08070.6 CCF51485.1 - 0.018 15.6 8.4 0.05 14.2 5.8 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region Pneumo_att_G PF05539.6 CCF51485.1 - 6 6.1 7.6 8 5.7 5.3 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.11 CCF51486.1 - 4.8e-31 107.7 23.2 7.3e-31 107.1 16.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF51486.1 - 1.3e-13 50.3 1.1 1.3e-13 50.3 0.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter CN_hydrolase PF00795.17 CCF51487.1 - 2.5e-22 79.1 0.0 3.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CCF51487.1 - 7.8e-22 77.3 0.0 5.9e-17 61.3 0.0 2.2 1 1 1 2 2 2 2 NAD synthase Fungal_trans PF04082.13 CCF51489.1 - 1.7e-28 99.1 0.0 2.9e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF51489.1 - 3.1e-07 30.1 8.5 6.5e-07 29.1 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec6 PF06046.8 CCF51490.1 - 6.4e-156 519.7 0.0 8.1e-156 519.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 NPV_P10 PF05531.7 CCF51490.1 - 0.082 13.1 0.9 0.89 9.8 0.0 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 CCF51491.1 - 0.0036 16.0 5.2 0.0051 15.5 3.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein APG6 PF04111.7 CCF51491.1 - 0.019 14.0 4.1 0.026 13.5 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Ndc1_Nup PF09531.5 CCF51491.1 - 0.044 12.2 1.8 0.073 11.4 1.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinetocho_Slk19 PF12709.2 CCF51491.1 - 0.048 13.7 7.0 0.11 12.5 1.9 2.5 1 1 1 2 2 2 0 Central kinetochore-associated DUF342 PF03961.8 CCF51491.1 - 0.055 11.8 2.4 0.072 11.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med9 PF07544.8 CCF51491.1 - 0.063 13.0 1.8 0.17 11.6 0.2 2.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.4 CCF51491.1 - 0.15 12.2 3.1 0.67 10.1 1.7 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 CCF51491.1 - 0.21 10.4 8.8 0.36 9.7 5.8 1.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 CCF51491.1 - 0.25 11.3 3.8 0.75 9.8 2.2 1.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 CCF51491.1 - 0.26 10.4 4.8 1.2 8.2 0.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4140 PF13600.1 CCF51491.1 - 2.5 8.5 6.0 4.3 7.8 1.2 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 CCF51491.1 - 4.9 6.9 14.6 19 5.0 10.1 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 CCF51491.1 - 5.2 6.5 7.6 7.1 6.1 4.4 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CHCH PF06747.8 CCF51492.1 - 1.9e-06 27.6 2.3 3.7e-06 26.6 1.6 1.5 1 0 0 1 1 1 1 CHCH domain RskA PF10099.4 CCF51492.1 - 0.0074 16.0 2.5 0.012 15.3 1.8 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PAP2 PF01569.16 CCF51494.1 - 5.5e-22 77.8 2.3 1.5e-21 76.3 1.6 1.8 1 0 0 1 1 1 1 PAP2 superfamily WD40 PF00400.27 CCF51495.1 - 5.7e-78 254.2 34.0 3.2e-13 48.9 0.0 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CCF51495.1 - 2.6e-07 29.1 3.2 0.0016 16.7 0.0 4.3 3 1 2 5 5 5 2 Nucleoporin Nup120/160 NLE PF08154.7 CCF51495.1 - 5.2e-06 26.3 0.3 9.9e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 NLE (NUC135) domain eIF2A PF08662.6 CCF51495.1 - 0.00018 21.2 0.1 0.0018 18.0 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CCF51495.1 - 0.027 14.1 0.1 1.2 8.9 0.0 3.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RXT2_N PF08595.6 CCF51495.1 - 0.066 13.0 0.2 12 5.7 0.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Proteasome_A_N PF10584.4 CCF51495.1 - 0.075 12.3 1.4 6.5 6.1 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF4604 PF15377.1 CCF51495.1 - 3.9 7.6 12.3 0.26 11.4 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) SURF6 PF04935.7 CCF51496.1 - 1.1e-50 171.9 31.9 1.1e-50 171.9 22.1 2.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 CCF51496.1 - 6.1e-15 55.0 3.4 6.1e-15 55.0 2.3 5.8 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Med2 PF11214.3 CCF51496.1 - 0.094 12.7 0.3 0.094 12.7 0.2 3.9 3 1 1 4 4 4 0 Mediator complex subunit 2 PEHE PF15275.1 CCF51496.1 - 0.41 11.1 0.0 0.41 11.1 0.0 3.9 4 1 0 4 4 4 0 PEHE domain EPSP_synthase PF00275.15 CCF51497.1 - 5.4e-112 374.2 0.0 7.4e-112 373.8 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCF51497.1 - 1.9e-95 318.7 0.0 6.5e-95 316.9 0.0 1.9 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCF51497.1 - 1.7e-62 211.0 0.0 3.1e-62 210.1 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 CCF51497.1 - 4.3e-27 93.9 0.0 1.2e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 CCF51497.1 - 3.4e-26 91.9 0.0 8.2e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 CCF51497.1 - 1.7e-10 41.0 0.0 4.5e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCF51497.1 - 7.2e-06 25.4 0.1 2.2e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase OCD_Mu_crystall PF02423.10 CCF51497.1 - 0.0026 16.5 0.5 0.029 13.1 0.1 2.2 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family ThiF PF00899.16 CCF51497.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 ThiF family Glyco_hydro_32N PF00251.15 CCF51500.1 - 2.3e-48 165.1 0.0 3.1e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CCF51500.1 - 4.8e-10 39.6 0.1 9.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 CCF51500.1 - 0.093 12.6 0.9 2.5 8.2 0.3 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Pil1 PF13805.1 CCF51501.1 - 2e-08 33.7 0.8 2e-08 33.7 0.6 2.2 2 0 0 2 2 2 1 Eisosome component PIL1 IMD PF08397.6 CCF51501.1 - 0.18 11.1 2.3 1.9 7.7 0.4 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Ras PF00071.17 CCF51502.1 - 5.7e-55 185.1 0.1 6.7e-55 184.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF51502.1 - 5.2e-18 65.6 0.0 6.6e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF51502.1 - 2.7e-16 59.3 0.0 3.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF51502.1 - 3.3e-05 23.8 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCF51502.1 - 0.00084 18.5 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF51502.1 - 0.0012 18.3 0.0 0.0029 17.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCF51502.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 CCF51502.1 - 0.057 12.9 0.1 0.081 12.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCF51502.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain zf-CSL PF05207.8 CCF51503.1 - 1.4e-25 88.5 1.2 2e-25 88.0 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.1 CCF51503.1 - 0.001 18.6 0.7 0.0016 18.0 0.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 CCF51503.1 - 0.018 14.6 0.8 0.027 14.0 0.6 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CCF51503.1 - 0.019 14.9 0.4 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 CCF51503.1 - 0.055 13.1 1.0 0.085 12.5 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Septin PF00735.13 CCF51505.1 - 4.9e-114 380.1 0.1 6.6e-114 379.6 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCF51505.1 - 2.3e-08 34.0 0.0 4.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCF51505.1 - 1.8e-07 30.4 0.1 4.3e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCF51505.1 - 3.4e-07 29.8 0.5 1.1e-05 25.0 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 CCF51505.1 - 5e-05 22.7 0.5 0.00013 21.4 0.3 1.7 1 1 0 1 1 1 1 Ras family AAA_24 PF13479.1 CCF51505.1 - 0.00018 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 CCF51505.1 - 0.00039 19.5 0.1 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_10 PF12846.2 CCF51505.1 - 0.00042 19.8 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Miro PF08477.8 CCF51505.1 - 0.00048 20.6 0.1 0.0013 19.1 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CCF51505.1 - 0.0008 19.5 0.6 0.0044 17.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF51505.1 - 0.001 19.0 0.5 0.0048 16.8 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.4 CCF51505.1 - 0.0012 18.3 1.9 0.087 12.3 0.1 3.0 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 CCF51505.1 - 0.0016 17.6 0.0 0.0041 16.2 0.0 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 CCF51505.1 - 0.0017 18.6 0.2 0.0052 17.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 CCF51505.1 - 0.0032 17.1 0.2 0.0076 15.9 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCF51505.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 CCF51505.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.13 CCF51505.1 - 0.023 13.9 0.1 0.073 12.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 CCF51505.1 - 0.025 14.1 0.2 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CCF51505.1 - 0.03 13.8 0.8 2.3 7.7 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CCF51505.1 - 0.035 13.9 0.4 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCF51505.1 - 0.036 14.3 0.5 0.092 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCF51505.1 - 0.04 13.3 2.9 0.079 12.4 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 CCF51505.1 - 0.05 13.0 0.1 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 CCF51505.1 - 0.05 13.4 6.8 1.1 9.0 0.2 2.7 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 CCF51505.1 - 0.076 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CCF51505.1 - 0.097 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 CCF51505.1 - 0.1 12.4 0.8 0.21 11.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain cobW PF02492.14 CCF51505.1 - 0.1 12.0 0.4 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 CCF51505.1 - 0.15 12.2 1.5 0.41 10.8 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CCF51505.1 - 0.4 10.3 3.3 6.3 6.3 0.2 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein ArgK PF03308.11 CCF51505.1 - 0.68 8.6 3.1 0.75 8.5 0.1 2.3 3 0 0 3 3 3 0 ArgK protein Cep57_CLD_2 PF14197.1 CCF51505.1 - 1.2 9.1 7.3 6.3 6.8 5.0 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Myc-LZ PF02344.10 CCF51505.1 - 2.2 7.9 5.7 6.2 6.5 0.2 2.9 2 0 0 2 2 2 0 Myc leucine zipper domain ENTH PF01417.15 CCF51506.1 - 1.2e-50 170.5 0.2 2.2e-50 169.7 0.1 1.5 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 CCF51506.1 - 6.6e-05 22.1 7.4 0.011 15.1 1.9 3.4 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.11 CCF51506.1 - 0.00015 20.6 0.5 0.00028 19.6 0.4 1.5 1 0 0 1 1 1 1 ANTH domain p450 PF00067.17 CCF51507.1 - 1.5e-29 102.9 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Npa1 PF11707.3 CCF51508.1 - 1.5e-102 343.0 0.0 7.3e-102 340.7 0.0 2.2 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Metallophos PF00149.23 CCF51509.1 - 7.3e-10 38.5 0.0 2.3e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCF51509.1 - 0.026 14.3 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GMC_oxred_N PF00732.14 CCF51510.1 - 5.8e-50 170.1 0.1 3e-48 164.4 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF51510.1 - 7.1e-38 130.1 0.0 1.3e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCF51510.1 - 3.4e-05 22.8 0.9 0.00028 19.8 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCF51510.1 - 0.00012 21.0 0.1 0.0063 15.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCF51510.1 - 0.0016 17.4 0.1 0.0026 16.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCF51510.1 - 0.0024 17.9 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCF51510.1 - 0.013 15.4 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCF51510.1 - 0.051 12.0 0.8 5.1 5.4 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CCF51510.1 - 0.061 12.4 0.3 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CCF51510.1 - 0.077 12.8 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 CCF51512.1 - 5.6e-33 113.9 0.1 8.5e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF51512.1 - 4.3e-09 36.1 10.0 7.1e-09 35.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4559 PF15112.1 CCF51512.1 - 1.1 8.3 1.5 1.7 7.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SUZ-C PF12901.2 CCF51513.1 - 0.3 10.7 1.4 2.9 7.6 0.2 2.4 2 0 0 2 2 2 0 SUZ-C motif TRAM_LAG1_CLN8 PF03798.11 CCF51514.1 - 4.2e-43 147.2 22.6 4.2e-43 147.2 15.7 2.6 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 CCF51514.1 - 2.2e-08 33.4 0.0 1.2e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 TRAM1-like protein rve PF00665.21 CCF51517.1 - 4.5e-14 52.5 0.0 7.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF51517.1 - 2.2e-10 40.0 1.4 1.9e-09 37.0 0.1 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CCF51518.1 - 2.7e-18 66.1 0.1 5.9e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CCF51518.1 - 0.0029 18.0 0.1 0.0057 17.1 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCF51518.1 - 0.0034 17.3 0.1 0.0087 16.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 CCF51519.1 - 2.3e-05 23.9 0.2 7.5e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CCF51519.1 - 0.0041 16.9 3.0 0.0088 15.9 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CCF51519.1 - 0.05 13.5 0.3 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 CCF51519.1 - 0.072 12.6 0.2 0.072 12.6 0.2 2.4 3 0 0 3 3 3 0 Zinc knuckle MFS_1 PF07690.11 CCF51520.1 - 9.8e-26 90.2 31.0 6.9e-25 87.5 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phos_pyr_kin PF08543.7 CCF51522.1 - 1e-73 247.5 1.2 1.6e-54 184.7 0.0 3.4 3 1 0 3 3 3 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCF51522.1 - 1.6e-33 116.2 0.2 2.5e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 CCF51522.1 - 0.006 15.7 0.1 3.4 6.7 0.0 2.6 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.19 CCF51522.1 - 0.068 12.2 0.0 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 pfkB family carbohydrate kinase MRP-L51 PF10244.4 CCF51522.1 - 0.15 12.1 0.1 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit Peptidase_S49 PF01343.13 CCF51523.1 - 4.7e-45 153.1 0.0 1.5e-26 93.0 0.0 2.8 3 0 0 3 3 3 2 Peptidase family S49 CLP_protease PF00574.18 CCF51523.1 - 5e-05 23.0 3.4 0.00031 20.4 0.1 2.8 3 0 0 3 3 3 1 Clp protease SDH_sah PF01972.11 CCF51523.1 - 0.0072 15.1 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Aminotran_5 PF00266.14 CCF51524.1 - 5.1e-22 78.1 0.0 8.4e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.11 CCF51524.1 - 1.4e-18 66.7 0.0 3.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CCF51524.1 - 5e-14 51.9 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MxiH PF09392.5 CCF51525.1 - 5 7.7 6.5 1.4 9.5 1.2 2.0 2 0 0 2 2 2 0 Type III secretion needle MxiH like DUF1074 PF06382.6 CCF51526.1 - 7.1 6.5 9.2 0.35 10.8 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1074) MMS19_N PF14500.1 CCF51527.1 - 1.3e-61 208.1 0.0 6.5e-50 169.8 0.0 4.0 3 1 0 3 3 3 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CCF51527.1 - 3.4e-43 147.9 0.0 6.8e-42 143.6 0.0 3.0 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal Arm PF00514.18 CCF51527.1 - 0.39 10.6 3.6 13 5.8 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CCF51527.1 - 1.2 9.7 9.0 94 3.6 0.0 6.1 5 0 0 5 5 5 0 HEAT-like repeat Glyco_hydro_20 PF00728.17 CCF51528.1 - 1.2e-25 90.4 0.0 2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Steroid_dh PF02544.11 CCF51529.1 - 2.3e-34 118.3 6.2 3.3e-34 117.8 4.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 CCF51529.1 - 0.00035 19.9 0.0 0.00064 19.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.7 CCF51529.1 - 0.0025 17.1 1.6 0.0035 16.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCF51529.1 - 0.043 13.9 0.7 0.12 12.4 0.5 1.8 1 1 0 1 1 1 0 Phospholipid methyltransferase Ubiquitin_2 PF14560.1 CCF51529.1 - 0.094 12.9 0.1 0.21 11.8 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain EmrE PF13536.1 CCF51529.1 - 1.2 9.3 11.9 0.29 11.3 2.5 2.5 2 1 1 3 3 3 0 Multidrug resistance efflux transporter SET PF00856.23 CCF51530.1 - 4.7e-15 56.2 0.1 4.7e-15 56.2 0.1 2.7 2 2 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 CCF51530.1 - 0.00025 20.9 0.0 0.00092 19.1 0.0 2.0 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Nop14 PF04147.7 CCF51530.1 - 0.0058 14.6 27.5 0.01 13.7 19.1 1.4 1 0 0 1 1 1 1 Nop14-like family Zn_clus PF00172.13 CCF51532.1 - 0.00039 20.2 7.9 0.00082 19.2 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OHCU_decarbox PF09349.5 CCF51533.1 - 3.8e-29 102.0 0.7 2.3e-28 99.4 0.0 2.4 2 1 0 2 2 2 1 OHCU decarboxylase DDRGK PF09756.4 CCF51533.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.4 1 1 1 2 2 2 0 DDRGK domain Y_phosphatase2 PF03162.8 CCF51534.1 - 1e-48 164.8 0.0 1.9e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Prefoldin PF02996.12 CCF51534.1 - 5.3e-30 103.5 0.0 9.4e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit Y_phosphatase3 PF13350.1 CCF51534.1 - 5.1e-08 33.3 0.6 3.7e-06 27.2 0.0 3.0 2 2 1 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCF51534.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LRR_4 PF12799.2 CCF51535.1 - 1.4e-07 31.0 3.1 0.00029 20.3 1.1 3.8 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CCF51535.1 - 0.0002 21.0 0.7 5.3 7.6 0.0 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CCF51535.1 - 0.01 15.8 1.0 6.3 7.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.1 CCF51535.1 - 0.016 14.9 5.1 0.64 9.8 0.0 3.8 5 1 0 5 5 5 0 Leucine rich repeat Nucleic_acid_bd PF13820.1 CCF51535.1 - 0.042 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative nucleic acid-binding region LRR_1 PF00560.28 CCF51535.1 - 4.2 7.7 6.6 17 5.9 0.1 4.1 5 1 1 6 6 6 0 Leucine Rich Repeat Annexin PF00191.15 CCF51536.1 - 1.6e-56 188.0 2.3 1.2e-16 60.3 0.0 5.0 4 1 0 4 4 4 4 Annexin Alk_phosphatase PF00245.15 CCF51537.1 - 2.5e-73 247.1 0.0 3.3e-72 243.5 0.0 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Ribosomal_L30_N PF08079.7 CCF51538.1 - 9.2e-25 86.4 16.4 1.4e-24 85.8 11.3 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CCF51538.1 - 4.5e-18 64.5 1.6 1.3e-17 63.1 1.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e NinG PF05766.7 CCF51538.1 - 0.19 11.4 4.3 0.32 10.7 3.0 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein APG12 PF04110.8 CCF51539.1 - 1.3e-31 108.6 0.1 1.9e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CCF51539.1 - 0.0066 16.4 0.0 0.0084 16.0 0.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like GAD-like PF08887.6 CCF51539.1 - 0.05 13.6 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain Ufm1 PF03671.9 CCF51539.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin fold modifier 1 protein FAD_binding_1 PF00667.15 CCF51540.1 - 3.2e-52 177.1 0.0 1e-51 175.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 CCF51540.1 - 2.4e-07 31.2 0.1 1.4e-06 28.8 0.0 2.3 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Macoilin PF09726.4 CCF51540.1 - 4 5.6 8.6 6.7 4.8 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Adeno_E3_CR2 PF02439.10 CCF51541.1 - 0.036 13.6 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 CCF51542.1 - 0.00095 18.4 0.1 0.0028 16.9 0.1 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 CCF51542.1 - 0.0026 16.6 0.0 0.0057 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 CCF51542.1 - 0.045 13.3 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 CCF51542.1 - 0.11 12.9 0.0 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF533 PF04391.7 CCF51542.1 - 5.5 6.3 16.8 0.98 8.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF533) Plasmodium_Vir PF05795.6 CCF51542.1 - 8.6 5.4 20.2 0.5 9.5 0.1 2.3 1 1 0 2 2 2 0 Plasmodium vivax Vir protein PEARLI-4 PF05278.7 CCF51544.1 - 0.073 12.4 2.7 0.13 11.6 1.9 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) ERM PF00769.14 CCF51544.1 - 1.5 8.3 11.3 0.054 13.0 3.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family ATG16 PF08614.6 CCF51544.1 - 7.7 6.2 10.7 0.86 9.3 3.8 2.1 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Thiolase_N PF00108.18 CCF51545.1 - 7.7e-97 323.3 4.4 1.2e-96 322.7 3.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF51545.1 - 3.4e-45 152.4 3.7 1.7e-44 150.1 0.7 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCF51545.1 - 4.3e-06 26.3 4.3 0.00026 20.5 1.3 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain BcrAD_BadFG PF01869.15 CCF51545.1 - 0.0072 15.6 1.6 0.016 14.4 0.1 2.2 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family ACP_syn_III PF08545.5 CCF51545.1 - 8.1 6.1 10.7 3 7.5 0.2 3.3 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-C2H2 PF00096.21 CCF51546.1 - 8.9e-11 41.4 20.0 8.4e-06 25.8 0.2 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF51546.1 - 1.2e-09 37.7 16.8 0.0005 20.2 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF51546.1 - 0.00018 21.5 17.3 0.035 14.4 0.4 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-Di19 PF05605.7 CCF51546.1 - 0.28 11.3 4.7 4.9 7.3 3.4 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 CCF51546.1 - 8.5 6.1 19.1 0.4 10.4 3.7 3.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF3408 PF11888.3 CCF51547.1 - 0.019 14.9 1.6 0.031 14.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SKN1 PF03935.10 CCF51549.1 - 2.4e-201 669.2 0.4 3e-201 668.9 0.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 CCF51549.1 - 7.6e-07 28.5 0.4 3.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Sas10_Utp3 PF04000.10 CCF51550.1 - 1e-08 35.2 0.0 2.1e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family GDI PF00996.13 CCF51551.1 - 4.2e-52 176.9 0.0 2.1e-50 171.3 0.0 2.0 2 0 0 2 2 2 2 GDP dissociation inhibitor AAA PF00004.24 CCF51552.1 - 1.9e-86 286.9 0.0 4.1e-43 146.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCF51552.1 - 6.6e-16 58.3 0.7 3.1e-08 33.4 0.3 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF51552.1 - 5.1e-14 52.6 2.5 1.4e-07 31.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 CCF51552.1 - 2.6e-11 43.0 0.0 4.8e-05 22.5 0.0 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCF51552.1 - 4.5e-10 39.7 0.7 0.00023 21.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCF51552.1 - 2.6e-09 37.9 0.3 4.8e-05 24.1 0.1 2.8 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCF51552.1 - 5.5e-09 35.2 0.0 0.0038 16.0 0.0 2.9 3 0 0 3 3 3 2 TIP49 C-terminus AAA_33 PF13671.1 CCF51552.1 - 1.1e-07 31.7 0.0 0.0001 22.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 CCF51552.1 - 2.3e-07 30.7 0.0 0.0018 18.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCF51552.1 - 7e-07 28.5 0.0 0.00029 20.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 CCF51552.1 - 1.2e-06 28.0 3.2 0.009 15.4 0.2 3.8 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CCF51552.1 - 1.3e-06 27.9 0.0 0.0079 15.6 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCF51552.1 - 4e-06 26.4 3.5 0.0031 17.2 0.2 4.1 3 0 0 3 3 3 1 Part of AAA domain AAA_28 PF13521.1 CCF51552.1 - 1.2e-05 25.2 0.7 0.024 14.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CCF51552.1 - 1.3e-05 25.2 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_2 PF07724.9 CCF51552.1 - 1.4e-05 25.0 0.0 0.25 11.2 0.0 3.1 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CCF51552.1 - 2.3e-05 24.4 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCF51552.1 - 9.3e-05 21.6 1.7 0.22 10.6 0.0 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCF51552.1 - 0.00032 21.0 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCF51552.1 - 0.00043 19.9 0.9 0.017 14.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCF51552.1 - 0.00044 19.8 0.1 1.6 8.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF51552.1 - 0.00084 18.8 0.0 2 7.8 0.0 3.8 3 1 0 3 3 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCF51552.1 - 0.0012 18.5 0.0 1.6 8.3 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase CDC48_N PF02359.13 CCF51552.1 - 0.002 18.0 0.0 0.0083 16.0 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Parvo_NS1 PF01057.12 CCF51552.1 - 0.0022 16.9 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CCF51552.1 - 0.0037 16.8 0.0 0.051 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 CCF51552.1 - 0.004 15.9 0.0 0.31 9.6 0.0 2.6 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 CCF51552.1 - 0.0044 16.6 0.9 0.19 11.3 0.1 3.4 3 1 0 3 3 2 1 NACHT domain DUF815 PF05673.8 CCF51552.1 - 0.005 15.8 0.0 0.049 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DAP3 PF10236.4 CCF51552.1 - 0.0084 15.0 0.0 0.033 13.1 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 UPF0079 PF02367.12 CCF51552.1 - 0.0098 15.5 0.1 0.36 10.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CCF51552.1 - 0.016 14.4 0.3 0.7 9.0 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 CCF51552.1 - 0.017 14.2 0.2 6.1 5.8 0.0 3.0 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 CCF51552.1 - 0.02 15.1 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 CCF51552.1 - 0.035 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 CCF51552.1 - 0.066 13.0 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 CCF51552.1 - 0.068 12.8 0.6 3.5 7.3 0.0 3.2 2 2 2 4 4 3 0 NTPase IPT PF01745.11 CCF51552.1 - 0.068 12.3 0.2 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Apc15p PF05841.6 CCF51555.1 - 7.4 7.3 6.9 8.9 7.0 0.3 2.7 2 1 0 2 2 2 0 Apc15p protein Abhydrolase_6 PF12697.2 CCF51556.1 - 3.2e-30 105.7 0.5 4.6e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF51556.1 - 4.8e-15 55.7 0.0 1e-14 54.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF51556.1 - 9e-11 41.7 0.0 1.3e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCF51556.1 - 0.00012 21.8 0.0 0.0006 19.6 0.0 2.0 1 1 1 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 CCF51556.1 - 0.0017 16.8 0.0 0.0029 16.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family EHN PF06441.7 CCF51556.1 - 0.0025 17.7 0.1 0.0056 16.5 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus APC_basic PF05956.6 CCF51556.1 - 0.032 13.3 0.6 0.032 13.3 0.4 1.4 2 0 0 2 2 2 0 APC basic domain DASH_Dad3 PF08656.5 CCF51557.1 - 9.3e-22 76.5 1.3 1.6e-21 75.8 0.9 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad3 adh_short PF00106.20 CCF51559.1 - 3e-35 121.6 0.1 3.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF51559.1 - 2e-14 53.6 0.0 2.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF51559.1 - 2.1e-11 44.0 0.0 2.8e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCF51559.1 - 3.5e-05 23.3 0.0 6.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CCF51559.1 - 6.4e-05 22.6 0.1 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CCF51559.1 - 0.00021 21.3 0.7 0.00064 19.7 0.5 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CCF51559.1 - 0.00023 20.8 0.1 0.00041 20.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCF51559.1 - 0.00075 18.6 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCF51559.1 - 0.0016 17.5 0.1 0.0021 17.1 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 CCF51559.1 - 0.0043 16.1 0.1 0.0097 14.9 0.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 CCF51559.1 - 0.054 12.9 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.8 CCF51559.1 - 0.13 11.4 0.1 1.3 8.2 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 CCF51559.1 - 0.15 10.9 0.0 0.31 9.8 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sec61_beta PF03911.11 CCF51560.1 - 0.77 9.6 3.0 1.2 9.0 2.1 1.2 1 0 0 1 1 1 0 Sec61beta family XPG_I PF00867.13 CCF51561.1 - 1.4e-25 89.1 0.0 2.8e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCF51561.1 - 1.6e-21 76.4 0.0 3.2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CCF51561.1 - 7e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 CCF51561.1 - 0.026 14.7 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Adeno_E1B_55K PF01696.12 CCF51561.1 - 0.097 11.1 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen LSM PF01423.17 CCF51562.1 - 8.1e-17 60.5 0.6 1e-16 60.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 CCF51562.1 - 0.025 14.2 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.12 CCF51562.1 - 0.098 12.3 0.7 0.28 10.8 0.4 1.8 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Phage_GPD PF05954.6 CCF51562.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Redoxin PF08534.5 CCF51563.1 - 1.4e-08 34.4 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCF51563.1 - 8.4e-07 28.7 0.0 1.3e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family DUF899 PF05988.7 CCF51563.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) WD40 PF00400.27 CCF51564.1 - 3.5e-41 137.6 14.7 5.4e-09 35.5 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF2415 PF10313.4 CCF51564.1 - 0.001 18.7 0.0 0.0078 15.8 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Nucleoporin_N PF08801.6 CCF51564.1 - 0.046 12.4 0.0 0.42 9.2 0.0 2.2 1 1 0 2 2 2 0 Nup133 N terminal like VCBS PF13517.1 CCF51564.1 - 0.098 13.0 0.1 0.8 10.1 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Mtc PF03820.12 CCF51565.1 - 1e-91 306.8 0.3 1.3e-91 306.5 0.2 1.1 1 0 0 1 1 1 1 Tricarboxylate carrier FA_hydroxylase PF04116.8 CCF51566.1 - 1e-14 54.8 24.0 4e-14 52.9 14.4 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily PHP PF02811.14 CCF51567.1 - 8.3e-08 32.2 0.1 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 PHP domain RNA_pol_I_A49 PF06870.7 CCF51568.1 - 3.5e-130 434.0 0.0 4.8e-130 433.5 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_M48 PF01435.13 CCF51569.1 - 3.7e-40 137.8 0.0 7.8e-40 136.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CCF51569.1 - 0.021 13.8 0.4 0.021 13.8 0.3 2.3 2 1 1 3 3 3 0 BlaR1 peptidase M56 SprT-like PF10263.4 CCF51569.1 - 0.06 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF955 PF06114.8 CCF51569.1 - 0.066 12.9 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Peptidase_MA_2 PF13485.1 CCF51569.1 - 0.069 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase MA superfamily PgaD PF13994.1 CCF51569.1 - 1.8 8.0 7.1 4.9 6.6 1.2 2.9 3 0 0 3 3 3 0 PgaD-like protein Fungal_trans PF04082.13 CCF51570.1 - 2.6e-42 144.5 0.0 3.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CCF51570.1 - 6e-08 32.5 10.5 0.0014 18.8 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF51570.1 - 3.1e-05 23.9 8.4 0.04 14.2 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCF51570.1 - 0.041 13.7 0.7 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF51570.1 - 0.074 13.3 4.8 0.058 13.7 0.9 2.3 2 0 0 2 2 2 0 Zinc-finger double domain SpoIIE PF07228.7 CCF51571.1 - 9.6e-07 28.6 0.2 0.14 11.8 0.0 3.4 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CCF51571.1 - 6.2e-06 25.7 0.2 6.2e-05 22.4 0.1 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CCF51571.1 - 0.00084 18.8 0.1 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C Cu-oxidase_3 PF07732.10 CCF51572.1 - 3.4e-39 133.2 5.7 2.7e-38 130.3 0.8 3.6 4 1 1 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.17 CCF51572.1 - 8.3e-34 116.7 0.1 1.3e-32 112.9 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCF51572.1 - 6.1e-32 110.0 10.0 4.1e-30 104.1 0.5 4.1 3 1 0 3 3 3 2 Multicopper oxidase Phosphoesterase PF04185.9 CCF51573.1 - 2.7e-23 82.7 3.6 5.8e-23 81.6 2.3 1.5 1 1 0 1 1 1 1 Phosphoesterase family CoA_transf_3 PF02515.12 CCF51573.1 - 0.018 14.3 0.1 0.031 13.5 0.1 1.4 1 0 0 1 1 1 0 CoA-transferase family III zf-C2H2 PF00096.21 CCF51575.1 - 0.00028 21.0 16.5 0.00083 19.5 1.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF51575.1 - 0.00029 20.9 13.6 0.0065 16.7 1.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF51575.1 - 0.0059 16.8 3.7 0.0059 16.8 2.6 3.1 4 0 0 4 4 4 1 Zinc-finger double domain GTP_EFTU PF00009.22 CCF51576.1 - 2.2e-56 190.3 0.1 4e-56 189.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCF51576.1 - 2.8e-34 117.2 0.1 8.3e-34 115.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CCF51576.1 - 9.7e-31 105.4 0.0 2.3e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCF51576.1 - 6e-22 77.3 0.1 1.6e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCF51576.1 - 3.6e-13 49.4 0.0 9.9e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SKN1 PF03935.10 CCF51577.1 - 3.8e-178 592.7 3.2 4.7e-178 592.4 2.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 CCF51579.1 - 4.4e-189 628.8 6.0 5.2e-189 628.5 4.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rot1 PF10681.4 CCF51580.1 - 4.8e-60 202.5 0.4 5.8e-60 202.2 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SKN1 PF03935.10 CCF51581.1 - 2.3e-182 606.6 0.8 2.7e-182 606.4 0.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Pyr_redox_3 PF13738.1 CCF51582.1 - 2.9e-23 83.0 0.0 4.4e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCF51582.1 - 1.8e-18 66.0 0.1 4.4e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCF51582.1 - 1.2e-12 48.1 0.0 6.7e-08 32.6 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF51582.1 - 8.5e-12 44.6 0.0 7e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCF51582.1 - 4e-09 36.3 1.1 3.2e-08 33.4 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCF51582.1 - 1.9e-06 28.2 0.2 0.084 13.2 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF51582.1 - 2.3e-05 23.5 0.2 0.0016 17.4 0.0 3.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 CCF51582.1 - 9.5e-05 21.4 1.1 0.03 13.2 0.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CCF51582.1 - 0.00026 20.8 7.9 0.2 11.3 0.0 4.4 5 0 0 5 5 5 2 FAD-NAD(P)-binding HI0933_like PF03486.9 CCF51582.1 - 0.00096 17.7 0.6 0.032 12.7 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CCF51582.1 - 0.0015 17.6 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family SIS PF01380.17 CCF51582.1 - 0.14 11.7 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 SIS domain FAD_binding_2 PF00890.19 CCF51582.1 - 0.29 9.9 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 1 0 FAD binding domain AMP-binding PF00501.23 CCF51583.1 - 2.4e-77 260.1 0.0 3.1e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF51583.1 - 6.6e-10 39.7 0.0 1.3e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TAFII28 PF04719.9 CCF51584.1 - 2.5e-25 88.1 0.1 3.8e-25 87.5 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Saccharop_dh PF03435.13 CCF51585.1 - 1.5e-110 369.7 0.4 2.1e-110 369.3 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 CCF51585.1 - 3.6e-90 301.1 0.0 2.2e-89 298.6 0.0 2.0 2 0 0 2 2 2 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 CCF51585.1 - 0.0019 18.4 0.5 0.006 16.8 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 CCF51585.1 - 0.069 13.6 0.1 0.51 10.8 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain 3Beta_HSD PF01073.14 CCF51585.1 - 0.075 11.7 0.2 0.17 10.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 CCF51585.1 - 0.13 12.4 0.9 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase RVT_1 PF00078.22 CCF51586.1 - 9.2e-07 28.4 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 CCF51587.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family Zn_clus PF00172.13 CCF51590.1 - 2.8e-05 23.9 13.5 4.5e-05 23.2 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-K PF11802.3 CCF51591.1 - 7.9e-05 22.0 8.7 0.00036 19.8 3.6 2.7 1 1 0 1 1 1 1 Centromere-associated protein K FeoC PF09012.5 CCF51591.1 - 0.038 13.6 1.3 0.19 11.4 0.0 2.8 3 1 0 3 3 3 0 FeoC like transcriptional regulator ResIII PF04851.10 CCF51592.1 - 7.7e-19 68.2 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCF51592.1 - 1.4e-14 53.6 0.0 3.8e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF51592.1 - 4.6e-14 52.2 0.0 1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CCF51592.1 - 0.00013 21.0 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein SNF2_N PF00176.18 CCF51592.1 - 0.00065 18.5 0.0 0.0011 17.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain cobW PF02492.14 CCF51592.1 - 0.002 17.5 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CCF51592.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain GDPD PF03009.12 CCF51592.1 - 0.049 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF2075 PF09848.4 CCF51592.1 - 0.049 12.6 0.0 0.092 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Na_Ca_ex PF01699.19 CCF51594.1 - 9.4e-42 141.9 29.6 9.2e-23 80.3 5.7 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 CCF51594.1 - 0.0096 15.7 0.3 0.0096 15.7 0.2 2.9 3 1 0 3 3 3 1 Eukaryotic protein of unknown function (DUF872) Pkinase PF00069.20 CCF51595.1 - 6.4e-75 251.6 0.0 8.8e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51595.1 - 6.5e-37 126.9 0.0 1e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51595.1 - 1.4e-08 34.0 0.0 2.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCF51595.1 - 0.0024 17.2 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 CCF51595.1 - 0.064 13.4 0.3 0.13 12.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) zf-C4H2 PF10146.4 CCF51595.1 - 0.23 11.4 1.4 1.3 8.9 1.0 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein YukC PF10140.4 CCF51595.1 - 0.25 9.8 0.0 0.43 9.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Corona_nucleoca PF00937.13 CCF51595.1 - 0.8 8.5 7.2 1.5 7.6 5.0 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein TPR_11 PF13414.1 CCF51596.1 - 9.7e-12 44.3 18.3 4.7e-06 26.1 1.9 5.9 5 1 1 6 6 5 4 TPR repeat TPR_2 PF07719.12 CCF51596.1 - 7e-09 34.9 26.1 0.0052 16.6 0.1 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF51596.1 - 4.3e-07 29.6 6.6 0.072 13.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF51596.1 - 8.1e-07 29.1 34.5 0.0053 17.2 1.0 8.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF51596.1 - 6.5e-06 25.5 4.0 0.045 13.5 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCF51596.1 - 4e-05 23.4 22.6 0.8 9.6 2.6 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCF51596.1 - 4.3e-05 22.9 16.4 0.024 14.2 0.2 5.5 7 0 0 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF51596.1 - 8.7e-05 22.5 7.0 0.1 12.7 0.1 5.4 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCF51596.1 - 0.00064 20.3 2.4 0.00064 20.3 1.6 7.8 8 2 1 9 9 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCF51596.1 - 0.014 15.1 4.4 3.2 7.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCF51596.1 - 0.014 15.2 12.6 7 6.5 0.9 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCF51596.1 - 0.07 13.4 27.9 0.28 11.5 0.2 6.6 5 1 1 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.5 CCF51596.1 - 0.19 10.4 0.4 0.38 9.4 0.3 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 CCF51596.1 - 1.8 8.6 8.3 1.3 9.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF51596.1 - 4.4 7.9 14.7 4.6 7.9 0.6 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Tubulin PF00091.20 CCF51597.1 - 4e-70 235.9 0.0 7.9e-70 235.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCF51597.1 - 1.5e-47 160.7 0.3 2.5e-47 160.0 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCF51597.1 - 1.2e-07 31.7 0.0 3.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCF51597.1 - 0.0017 17.8 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Mago_nashi PF02792.9 CCF51598.1 - 1.5e-74 248.4 0.3 1.7e-74 248.3 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DRY_EERY PF09750.4 CCF51599.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.3 2 1 0 2 2 2 0 Alternative splicing regulator Cpn60_TCP1 PF00118.19 CCF51600.1 - 1.8e-119 399.5 4.8 2.1e-119 399.2 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 CCF51600.1 - 0.14 11.8 1.4 0.3 10.7 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Cpn10 PF00166.16 CCF51601.1 - 2.3e-25 88.3 0.0 2.6e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Actin PF00022.14 CCF51602.1 - 8.3e-45 152.8 0.0 2.2e-41 141.6 0.0 2.6 2 1 0 2 2 2 2 Actin ThiF PF00899.16 CCF51603.1 - 0.00083 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCF51603.1 - 0.066 12.8 0.0 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 MoeZ/MoeB domain Mcm10 PF09332.6 CCF51603.1 - 3.3 6.9 6.6 5.3 6.2 4.5 1.2 1 0 0 1 1 1 0 Mcm10 replication factor SMC_N PF02463.14 CCF51604.1 - 2.9e-67 226.1 0.0 1.2e-66 224.0 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCF51604.1 - 3.7e-22 78.5 0.3 1.7e-21 76.3 0.2 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCF51604.1 - 4.7e-12 46.4 14.4 9.5e-06 25.7 1.3 4.0 3 1 0 3 3 3 2 AAA domain Cast PF10174.4 CCF51604.1 - 8.8e-06 24.0 46.0 8.8e-06 24.0 31.9 3.5 2 1 1 3 3 2 1 RIM-binding protein of the cytomatrix active zone MscS_porin PF12795.2 CCF51604.1 - 1.3e-05 24.6 18.6 1.3e-05 24.6 12.9 6.2 5 1 0 5 5 5 2 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 CCF51604.1 - 3.6e-05 23.1 30.5 8.1e-05 21.9 0.8 5.9 3 2 2 6 6 6 2 Reovirus sigma C capsid protein Spc7 PF08317.6 CCF51604.1 - 6.7e-05 21.7 17.7 6.7e-05 21.7 12.3 7.0 2 2 4 7 7 7 3 Spc7 kinetochore protein AAA_29 PF13555.1 CCF51604.1 - 6.7e-05 22.3 0.3 0.00057 19.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CCF51604.1 - 0.00015 22.1 47.1 0.00015 22.1 32.6 6.4 2 2 0 2 2 1 1 AAA domain AAA_13 PF13166.1 CCF51604.1 - 0.0021 16.6 89.1 0.0034 15.9 15.1 6.2 3 2 3 6 6 6 4 AAA domain Tropomyosin_1 PF12718.2 CCF51604.1 - 0.0024 17.7 9.3 0.0024 17.7 6.5 8.8 3 2 6 9 9 7 2 Tropomyosin like ADIP PF11559.3 CCF51604.1 - 0.0039 17.0 6.7 0.0039 17.0 4.6 8.3 4 3 4 9 9 9 2 Afadin- and alpha -actinin-Binding ABC_tran PF00005.22 CCF51604.1 - 0.05 13.8 0.2 0.05 13.8 0.1 6.4 2 2 1 5 5 4 0 ABC transporter Filament PF00038.16 CCF51604.1 - 0.097 12.1 83.6 0.093 12.1 15.4 6.9 2 2 4 6 6 6 0 Intermediate filament protein DUF869 PF05911.6 CCF51604.1 - 1.7 6.7 83.8 0.13 10.5 22.6 3.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Pirin PF02678.11 CCF51605.1 - 1.5e-26 92.3 4.9 1.8e-26 92.1 1.0 2.1 2 0 0 2 2 2 1 Pirin Cupin_2 PF07883.6 CCF51605.1 - 2.6e-10 39.6 5.8 7.1e-08 31.8 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 CCF51605.1 - 0.33 10.3 3.7 1.6 8.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) AAA_2 PF07724.9 CCF51606.1 - 3.3e-34 118.2 0.1 1.2e-26 93.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCF51606.1 - 1.4e-13 51.1 0.0 2.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF51606.1 - 7.7e-07 29.2 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCF51606.1 - 1.7e-06 28.2 0.0 4.6e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 CCF51606.1 - 3.1e-05 22.9 0.0 5.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CCF51606.1 - 6e-05 22.7 0.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 CCF51606.1 - 6e-05 22.8 0.0 0.00028 20.7 0.0 2.1 1 1 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 CCF51606.1 - 0.00013 22.8 0.0 0.00028 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF51606.1 - 0.0011 18.8 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CCF51606.1 - 0.0028 17.9 0.0 0.0075 16.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Mg_chelatase PF01078.16 CCF51606.1 - 0.0067 15.6 0.0 0.06 12.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCF51606.1 - 0.0085 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCF51606.1 - 0.018 14.6 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCF51606.1 - 0.027 13.9 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G0-G1_switch_2 PF15103.1 CCF51606.1 - 0.03 14.5 1.2 0.73 10.0 0.2 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 NACHT PF05729.7 CCF51606.1 - 0.032 13.8 0.1 0.069 12.8 0.1 1.6 1 1 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 CCF51606.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CCF51606.1 - 0.043 13.4 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CCF51606.1 - 0.054 12.3 0.2 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 CCF51606.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCF51606.1 - 0.089 12.2 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 CCF51606.1 - 0.15 11.7 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 CCF51606.1 - 0.38 10.0 0.0 0.63 9.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Pkinase PF00069.20 CCF51607.1 - 4.2e-69 232.5 6.8 5.4e-65 219.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51607.1 - 1.4e-36 125.9 0.0 1.6e-33 115.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 CCF51607.1 - 8.8e-18 63.4 0.3 8.8e-18 63.4 0.2 1.6 2 0 0 2 2 2 1 Kinase associated domain 1 Kdo PF06293.9 CCF51607.1 - 1.5e-05 24.1 0.0 3.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCF51607.1 - 0.0007 18.6 0.0 0.0007 18.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like WaaY PF06176.6 CCF51607.1 - 0.014 14.6 0.2 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 CCF51607.1 - 1.4 7.7 0.0 2.2 7.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.15 CCF51607.1 - 5.1 6.6 8.9 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase MFS_1 PF07690.11 CCF51608.1 - 5.7e-22 77.8 5.9 7.2e-14 51.2 3.8 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF51608.1 - 0.0033 16.0 5.5 0.022 13.3 3.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRAPPC10 PF12584.3 CCF51609.1 - 1.8e-25 89.1 0.0 3.4e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DNA_ligase_A_M PF01068.16 CCF51610.1 - 5.2e-56 189.2 0.0 1.6e-55 187.6 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCF51610.1 - 1.4e-54 184.5 0.4 2.3e-54 183.8 0.3 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCF51610.1 - 2.3e-23 82.3 0.0 6.8e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CCF51610.1 - 0.0053 16.4 0.5 0.73 9.5 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain eIF-3c_N PF05470.7 CCF51610.1 - 1.6 6.7 6.3 18 3.2 4.3 2.1 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mito_carr PF00153.22 CCF51611.1 - 2.8e-72 238.5 1.1 1.3e-25 88.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EOS1 PF12326.3 CCF51612.1 - 4.9e-19 68.4 0.0 1.9e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 N-glycosylation protein Carb_kinase PF01256.12 CCF51613.1 - 1.6e-50 171.7 0.0 2.1e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CCF51613.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF3337 PF11816.3 CCF51614.1 - 4e-85 286.1 0.0 2.5e-83 280.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 CCF51614.1 - 8.1e-28 95.2 24.4 4.1e-08 32.8 0.0 7.6 6 1 0 6 6 6 5 WD domain, G-beta repeat MutS_V PF00488.16 CCF51615.1 - 1.3e-69 234.2 0.0 2.3e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCF51615.1 - 2.1e-53 181.1 4.4 5.1e-53 179.8 2.9 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCF51615.1 - 1.8e-17 63.4 0.0 3.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCF51615.1 - 3.9e-06 26.9 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 CCF51615.1 - 0.11 12.7 0.1 0.11 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 CCF51616.1 - 4.5e-63 213.0 0.0 1.1e-62 211.7 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) tRNA-synt_1e PF01406.14 CCF51616.1 - 0.12 11.5 0.5 0.2 10.7 0.4 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF913 PF06025.7 CCF51616.1 - 0.34 9.5 2.1 0.62 8.7 1.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hexapep PF00132.19 CCF51617.1 - 4.4e-12 44.9 8.1 9.3e-10 37.5 3.4 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCF51617.1 - 7.4e-12 44.6 5.6 1.8e-09 36.9 2.1 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 CCF51617.1 - 9.6e-10 38.3 0.1 3.9e-09 36.3 0.1 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase zf-DHHC PF01529.15 CCF51618.1 - 0.12 11.7 0.2 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3395 PF11875.3 CCF51618.1 - 0.4 10.3 17.9 1.1 8.8 12.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) EIIBC-GUT_N PF03612.9 CCF51618.1 - 2.8 7.5 12.9 11 5.6 8.9 2.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Baculo_PP31 PF05311.6 CCF51618.1 - 4.3 6.5 12.3 14 4.8 8.6 1.8 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Amino_oxidase PF01593.19 CCF51619.1 - 1e-41 143.5 1.6 7.1e-28 97.8 0.0 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCF51619.1 - 1.8e-12 47.0 0.2 1.1e-11 44.6 0.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCF51619.1 - 1.8e-08 33.6 0.2 2.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCF51619.1 - 3.2e-08 32.8 0.0 6.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF51619.1 - 3.6e-07 29.0 1.3 3.5e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 CCF51619.1 - 2e-06 27.0 0.2 3.4e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCF51619.1 - 2.3e-06 27.6 0.0 7.1e-06 26.0 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF51619.1 - 2.7e-06 27.6 0.3 2.4e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCF51619.1 - 5.5e-06 25.7 0.0 8.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCF51619.1 - 1.8e-05 23.9 1.1 5.6e-05 22.3 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CCF51619.1 - 2.4e-05 24.5 0.1 5.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF51619.1 - 0.00012 21.1 0.1 0.00023 20.2 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CCF51619.1 - 0.00012 21.1 0.0 0.00021 20.2 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CCF51619.1 - 0.14 11.9 0.1 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Gti1_Pac2 PF09729.4 CCF51621.1 - 3.7e-57 192.8 1.7 8.5e-57 191.6 0.0 2.4 2 1 0 2 2 2 1 Gti1/Pac2 family HSA PF07529.8 CCF51622.1 - 2.4e-17 62.4 4.2 2.4e-17 62.4 2.9 3.9 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 CCF51622.1 - 2.8e-07 30.5 0.1 2.8e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Exo_endo_phos PF03372.18 CCF51623.1 - 2.1e-13 50.7 0.4 1.6e-12 47.8 0.3 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Daxx PF03344.10 CCF51623.1 - 6.2 5.1 20.3 0.075 11.5 8.6 1.6 2 0 0 2 2 2 0 Daxx Family Syja_N PF02383.13 CCF51624.1 - 1.1e-91 306.9 0.0 1.5e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain zf-met PF12874.2 CCF51625.1 - 1.2e-06 28.5 1.2 3e-06 27.2 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 CCF51625.1 - 0.047 12.9 0.4 0.091 12.0 0.3 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Proteasome PF00227.21 CCF51626.1 - 2.9e-28 98.4 0.0 3.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Phyto_Pns9_10 PF05878.6 CCF51626.1 - 0.0016 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 Glycos_trans_3N PF02885.12 CCF51626.1 - 0.0018 17.7 0.0 0.077 12.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Cu-oxidase_3 PF07732.10 CCF51628.1 - 1.2e-43 147.6 0.0 1.2e-43 147.6 0.0 3.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 CCF51628.1 - 3.6e-30 104.9 0.0 2e-29 102.5 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCF51628.1 - 3e-29 101.2 0.8 1e-27 96.3 0.4 4.7 5 0 0 5 5 5 3 Multicopper oxidase Zip PF02535.17 CCF51628.1 - 4 6.3 22.3 6.5 5.6 15.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LAG1-DNAbind PF09271.6 CCF51629.1 - 7.6e-26 91.2 0.8 3.8e-24 85.7 0.1 3.3 2 1 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 CCF51629.1 - 5.4e-16 58.7 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Rad60-SLD PF11976.3 CCF51630.1 - 9.8e-27 92.4 0.2 1.1e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCF51630.1 - 1.4e-12 46.8 0.0 1.7e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF4115 PF13464.1 CCF51630.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4115) Spidroin_MaSp PF11260.3 CCF51631.1 - 0.068 13.2 3.3 0.078 13.0 2.3 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Nuc_recep-AF1 PF11825.3 CCF51631.1 - 0.17 11.8 1.3 0.18 11.6 0.9 1.1 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 SseC PF04888.7 CCF51631.1 - 0.17 11.1 3.8 0.2 10.9 2.6 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Pardaxin PF07425.6 CCF51631.1 - 0.48 9.8 12.5 0.29 10.5 1.0 3.1 1 1 2 3 3 3 0 Pardaxin Coiled PF05710.7 CCF51631.1 - 9.1 6.8 9.5 30 5.1 6.6 1.9 1 1 0 1 1 1 0 Coiled coil TPR_11 PF13414.1 CCF51632.1 - 8.4e-54 179.1 36.3 2.4e-15 55.9 0.8 7.1 3 3 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 CCF51632.1 - 5.5e-38 127.0 21.5 1e-05 24.9 0.0 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCF51632.1 - 1e-37 124.9 20.0 0.00013 21.5 0.6 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.1 CCF51632.1 - 7e-22 75.7 9.3 0.00018 21.4 0.0 9.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCF51632.1 - 2.2e-20 72.3 16.1 2.5e-05 24.1 0.4 6.7 3 3 5 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCF51632.1 - 4e-20 71.9 26.0 6.5e-05 23.4 0.0 7.1 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCF51632.1 - 2.4e-17 61.3 15.6 0.003 17.2 0.0 9.8 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCF51632.1 - 9.9e-16 56.8 20.4 0.12 13.1 0.0 12.0 6 4 7 13 13 12 5 Tetratricopeptide repeat Apc3 PF12895.2 CCF51632.1 - 4.5e-12 45.9 13.5 0.0047 17.0 0.4 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCF51632.1 - 1.1e-11 43.5 6.4 0.016 14.9 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCF51632.1 - 1.3e-10 41.4 18.2 0.00084 19.6 0.9 7.1 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 CCF51632.1 - 4.9e-09 35.9 1.6 4.1e-05 23.3 0.0 5.5 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCF51632.1 - 0.022 15.1 24.4 23 5.7 0.0 9.5 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCF51632.1 - 0.1 12.5 2.9 16 5.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCF51632.1 - 0.3 10.3 5.4 37 3.6 0.4 4.6 4 0 0 4 4 4 0 SHNi-TPR Pex14_N PF04695.8 CCF51632.1 - 3 7.8 15.2 0.47 10.4 4.9 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_3 PF07720.7 CCF51632.1 - 7.3 6.5 11.5 1.1 9.0 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat PALP PF00291.20 CCF51633.1 - 3.1e-50 171.1 0.8 2.2e-49 168.3 0.6 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Complex1_LYR_2 PF13233.1 CCF51634.1 - 3.1e-12 46.8 0.4 3.1e-12 46.8 0.3 1.6 2 0 0 2 2 2 1 Complex1_LYR-like DUF719 PF05334.8 CCF51634.1 - 0.56 10.2 2.4 2.9 7.8 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF719) COMPASS-Shg1 PF05205.7 CCF51635.1 - 0.00038 20.7 0.0 0.0019 18.4 0.0 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4611 PF15387.1 CCF51635.1 - 0.036 14.1 4.5 0.082 13.0 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4484 PF14831.1 CCF51635.1 - 0.079 13.0 2.0 6.8 6.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Nucleoplasmin PF03066.10 CCF51635.1 - 0.095 12.2 6.2 0.15 11.5 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CCF51635.1 - 0.14 11.9 2.7 0.44 10.3 1.2 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 CCF51635.1 - 1.7 8.9 6.7 3.4 8.0 4.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.6 CCF51635.1 - 6.1 6.0 14.6 0.052 12.8 4.2 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2347 PF09804.4 CCF51636.1 - 2.8e-44 151.5 0.0 2.1e-42 145.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 CCF51636.1 - 0.0049 15.4 0.0 0.0085 14.6 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.7 CCF51636.1 - 0.0056 16.7 2.2 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR2 PF06218.6 CCF51636.1 - 0.49 9.0 0.0 0.76 8.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogen permease regulator 2 Mito_carr PF00153.22 CCF51637.1 - 5.9e-67 221.4 4.9 9.6e-24 82.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Evr1_Alr PF04777.8 CCF51638.1 - 1.3e-28 98.7 0.2 3.5e-28 97.3 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family COX16 PF14138.1 CCF51638.1 - 8.9e-27 93.0 0.1 1.6e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF2630 PF10944.3 CCF51638.1 - 0.011 15.8 1.5 0.024 14.7 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) ACPS PF01648.15 CCF51639.1 - 1.2e-30 105.7 0.1 2.8e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PLA2_B PF01735.13 CCF51639.1 - 6.2e-16 57.6 0.0 1.3e-12 46.7 0.0 3.1 3 0 0 3 3 3 3 Lysophospholipase catalytic domain DEAD PF00270.24 CCF51641.1 - 2.3e-10 40.2 0.0 5e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF51641.1 - 0.024 14.4 0.0 0.079 12.8 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Longin PF13774.1 CCF51642.1 - 3e-28 97.2 0.2 4.4e-28 96.6 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCF51642.1 - 2e-15 56.1 0.1 4.7e-15 54.9 0.0 1.6 1 1 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 CCF51642.1 - 0.015 15.0 0.3 0.015 15.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF816 PF05674.7 CCF51642.1 - 0.039 13.6 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) BTB_2 PF02214.17 CCF51643.1 - 0.00028 21.0 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_S10 PF00338.17 CCF51644.1 - 4.2e-21 74.5 0.0 1.1e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DUF1708 PF08101.6 CCF51647.1 - 6.3e-18 64.8 1.5 1.2e-14 53.9 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CCF51647.1 - 1.8e-05 24.3 0.0 0.00048 19.7 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain FA_hydroxylase PF04116.8 CCF51648.1 - 1.9e-15 57.2 17.3 1.9e-15 57.2 12.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Bromodomain PF00439.20 CCF51649.1 - 1.9e-20 72.5 0.0 3.3e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain CDC45 PF02724.9 CCF51649.1 - 0.22 9.5 23.2 0.085 10.8 2.1 2.3 2 0 0 2 2 2 0 CDC45-like protein WD40 PF00400.27 CCF51650.1 - 1.3e-54 180.1 14.2 3.9e-09 36.0 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCF51650.1 - 0.0012 17.0 0.9 7 4.6 0.0 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCF51650.1 - 0.0051 16.2 1.3 4 6.8 0.0 2.7 1 1 0 2 2 2 2 PQQ-like domain TFIIS_M PF07500.9 CCF51651.1 - 4.8e-28 97.5 2.2 4.8e-28 97.5 1.6 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CCF51651.1 - 4.9e-19 67.6 9.2 8e-19 66.9 6.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CCF51651.1 - 9.5e-14 50.6 0.4 2.5e-13 49.3 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zinc_ribbon_5 PF13719.1 CCF51651.1 - 0.037 13.5 4.2 0.11 12.0 0.4 2.9 2 0 0 2 2 2 0 zinc-ribbon domain HTH_22 PF13309.1 CCF51651.1 - 0.049 13.3 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 HTH domain zinc_ribbon_4 PF13717.1 CCF51651.1 - 0.075 12.7 4.3 0.23 11.1 0.4 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Ammonium_transp PF00909.16 CCF51652.1 - 2.5e-113 378.5 33.4 2.9e-113 378.3 23.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MRP-S28 PF10213.4 CCF51653.1 - 3.2e-37 127.4 0.0 5.5e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FliD_N PF02465.13 CCF51653.1 - 0.49 10.7 6.5 0.52 10.7 3.7 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AAA_33 PF13671.1 CCF51654.1 - 8e-15 54.9 0.1 4.4e-14 52.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 CCF51654.1 - 2e-08 34.3 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_22 PF13401.1 CCF51654.1 - 1.6e-05 25.0 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF51654.1 - 1.7e-05 25.6 0.0 3.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCF51654.1 - 0.0025 16.7 0.0 0.0057 15.5 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 CCF51654.1 - 0.0053 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CCF51654.1 - 0.0078 16.5 0.0 0.021 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Homeobox_KN PF05920.6 CCF51654.1 - 0.026 14.2 0.5 0.076 12.7 0.3 1.8 1 0 0 1 1 1 0 Homeobox KN domain UPF0079 PF02367.12 CCF51654.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CCF51654.1 - 0.055 13.4 0.2 0.14 12.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCF51654.1 - 0.086 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 CCF51654.1 - 0.13 11.8 0.0 0.62 9.6 0.0 2.0 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein SIR2 PF02146.12 CCF51655.1 - 7.6e-52 175.6 0.0 1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family adh_short PF00106.20 CCF51656.1 - 1.6e-29 102.9 0.6 2.2e-29 102.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF51656.1 - 2.8e-16 60.0 0.1 3.5e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF51656.1 - 1.5e-09 37.7 0.2 2.2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CCF51656.1 - 9.9e-06 24.8 0.0 8.4e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 CCF51656.1 - 0.00024 20.5 0.0 0.00076 18.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lactamase_B_2 PF12706.2 CCF51657.1 - 4.1e-30 104.7 0.1 8.5e-30 103.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCF51657.1 - 1.3e-06 28.1 0.1 1.8e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF51657.1 - 0.018 14.6 1.7 0.045 13.3 1.2 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily A_deamin PF02137.13 CCF51658.1 - 1.6e-55 188.7 0.1 2.2e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Dala_Dala_lig_C PF07478.8 CCF51659.1 - 0.023 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Rubella_E2 PF05749.6 CCF51660.1 - 0.0026 17.0 2.0 0.015 14.6 2.2 1.6 2 0 0 2 2 2 1 Rubella membrane glycoprotein E2 F-box-like PF12937.2 CCF51660.1 - 0.0027 17.3 0.1 0.0087 15.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like Peptidase_M20 PF01546.23 CCF51661.1 - 9.1e-23 80.7 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCF51661.1 - 1.2e-12 47.5 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CCF51661.1 - 0.045 13.4 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M28 DER1 PF04511.10 CCF51662.1 - 2.3e-31 108.8 0.1 3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Der1-like family zf-CCHC PF00098.18 CCF51663.1 - 6e-14 51.2 22.7 9.8e-05 22.1 1.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 CCF51663.1 - 1.9e-06 27.2 14.0 0.018 14.5 1.7 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 CCF51663.1 - 2.6e-06 27.0 25.1 0.013 15.1 0.7 4.6 4 0 0 4 4 4 4 Zinc knuckle Mem_trans PF03547.13 CCF51663.1 - 0.45 8.7 3.1 0.47 8.6 2.1 1.2 1 0 0 1 1 1 0 Membrane transport protein ORC6 PF05460.8 CCF51663.1 - 4.9 6.1 31.9 0.29 10.2 18.3 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Mucin PF01456.12 CCF51663.1 - 9 6.0 11.7 17 5.1 8.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Methyltransf_31 PF13847.1 CCF51664.1 - 1.2e-11 44.4 0.2 1.7e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCF51664.1 - 6.1e-10 38.7 0.0 8.5e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCF51664.1 - 1.1e-08 35.6 0.0 2.7e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CCF51664.1 - 3.5e-08 32.7 0.0 5.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 CCF51664.1 - 9.3e-08 32.4 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF51664.1 - 1.1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF51664.1 - 2.5e-06 27.4 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCF51664.1 - 7.1e-06 24.9 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 CCF51664.1 - 9.9e-06 25.9 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF51664.1 - 0.00011 21.6 0.3 0.00023 20.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CCF51664.1 - 0.00011 22.4 0.0 0.00026 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCF51664.1 - 0.00051 19.2 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CCF51664.1 - 0.002 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 CCF51664.1 - 0.035 13.5 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 CCF51664.1 - 0.057 12.4 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 CCF51664.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 CCF51664.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-CCHC PF00098.18 CCF51665.1 - 0.00036 20.3 1.9 0.00077 19.2 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCF51665.1 - 0.023 14.4 0.8 0.047 13.4 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle V-SNARE_C PF12352.3 CCF51666.1 - 7.7e-16 57.9 1.7 1.9e-15 56.6 1.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCF51666.1 - 5e-07 29.3 0.2 1.2e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Sec20 Mito_fiss_reg PF05308.6 CCF51666.1 - 0.02 14.2 0.1 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Sec8_exocyst PF04048.9 CCF51666.1 - 0.059 12.9 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain GlnD_UR_UTase PF08335.6 CCF51666.1 - 0.19 11.5 2.8 1.2 9.0 0.8 2.2 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase Wbp11 PF09429.5 CCF51666.1 - 0.25 11.3 3.5 0.21 11.5 0.5 2.3 3 0 0 3 3 3 0 WW domain binding protein 11 Oxidored_q6 PF01058.17 CCF51667.1 - 2.7e-21 75.5 0.1 4e-21 74.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 CCF51669.1 - 1.4e-46 158.7 0.0 2.4e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51669.1 - 1.1e-17 64.0 0.0 3.7e-17 62.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF51669.1 - 0.00025 20.8 0.2 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCF51669.1 - 0.0022 17.0 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCF51669.1 - 0.0055 15.7 0.2 0.009 15.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CCF51670.1 - 5.7e-16 57.7 9.2 2.4e-07 30.3 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat DPPIV_N PF00930.16 CCF51670.1 - 0.021 13.4 0.4 0.48 8.9 0.2 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 CCF51670.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DAP3 PF10236.4 CCF51671.1 - 1.3e-73 247.6 2.0 1.6e-73 247.3 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 CCF51671.1 - 2.7e-06 27.2 0.0 0.00093 18.9 0.0 2.6 2 1 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 CCF51671.1 - 2.7e-06 27.4 2.2 4.3e-06 26.8 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCF51671.1 - 0.0064 16.6 0.8 0.053 13.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCF51671.1 - 0.013 14.9 0.1 0.07 12.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCF51671.1 - 0.029 14.1 0.0 0.081 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 CCF51671.1 - 0.043 12.7 0.2 0.23 10.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Zot PF05707.7 CCF51671.1 - 0.081 12.3 0.0 0.3 10.5 0.0 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) KH_1 PF00013.24 CCF51673.1 - 4.9e-40 134.9 9.8 4.6e-14 51.8 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCF51673.1 - 2.8e-29 100.2 21.5 5.4e-10 38.6 0.1 4.1 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CCF51673.1 - 2.8e-15 55.6 6.3 1.1e-05 24.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCF51673.1 - 6.9e-05 22.4 7.8 0.09 12.4 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 CCF51673.1 - 0.028 14.2 6.5 3.7 7.4 0.1 3.5 3 0 0 3 3 3 0 NusA-like KH domain LSM PF01423.17 CCF51674.1 - 8e-12 44.5 0.0 1e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCF51674.1 - 0.00019 21.2 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PX PF00787.19 CCF51675.1 - 1.5e-24 85.9 0.0 2.5e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 PX domain TMF_DNA_bd PF12329.3 CCF51676.1 - 0.0033 17.2 9.2 0.0033 17.2 6.4 2.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding BAMBI PF06211.7 CCF51676.1 - 0.0074 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain DUF641 PF04859.7 CCF51676.1 - 0.027 14.2 5.3 0.11 12.2 3.7 2.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 CCF51676.1 - 3.8 5.2 2.6 6.2 4.5 1.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XPG_N PF00752.12 CCF51677.1 - 2.2e-35 120.9 0.0 5.2e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCF51677.1 - 2.5e-29 101.1 0.0 6e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCF51677.1 - 4.6e-08 33.2 0.1 1.4e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 CCF51677.1 - 0.0088 16.1 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4192 PF13830.1 CCF51677.1 - 0.026 14.1 0.3 0.42 10.1 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DNA_pol_lambd_f PF10391.4 CCF51677.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda COQ7 PF03232.8 CCF51678.1 - 6.4e-61 204.7 0.1 9.4e-61 204.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 FAD_binding_3 PF01494.14 CCF51678.1 - 2.6e-13 49.7 15.6 7.1e-08 31.8 0.6 4.2 3 1 1 4 4 4 3 FAD binding domain SE PF08491.5 CCF51678.1 - 3.1e-05 22.9 0.1 0.00032 19.6 0.0 2.0 1 1 1 2 2 2 1 Squalene epoxidase DAO PF01266.19 CCF51678.1 - 0.0011 17.8 0.0 0.003 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CCF51678.1 - 0.026 13.1 0.0 0.31 9.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 CCF51678.1 - 0.046 13.4 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Rubrerythrin PF02915.12 CCF51678.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Rubrerythrin Pyr_redox PF00070.22 CCF51678.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hpt PF01627.18 CCF51678.1 - 0.13 12.3 3.6 0.51 10.3 0.1 3.0 2 1 0 2 2 2 0 Hpt domain Cyclin PF08613.6 CCF51679.1 - 2.4e-16 60.4 0.9 3.2e-13 50.3 0.0 2.7 2 1 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 CCF51679.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain SPX PF03105.14 CCF51679.1 - 0.76 9.5 5.5 3.6 7.2 3.8 2.1 1 1 0 1 1 1 0 SPX domain Pkinase PF00069.20 CCF51680.1 - 2.8e-29 102.0 0.0 3.2e-28 98.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51680.1 - 4e-15 55.5 0.0 1.1e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCF51680.1 - 7.3e-05 22.6 0.2 0.00016 21.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCF51680.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCF51680.1 - 0.061 12.2 0.0 0.21 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like GATase_4 PF13230.1 CCF51681.1 - 5.2e-20 71.2 0.0 1e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCF51681.1 - 4.4e-10 39.6 0.0 1.9e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CCF51681.1 - 4.4e-09 35.5 0.0 6.1e-08 31.7 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 CCF51681.1 - 0.021 14.5 0.0 0.74 9.5 0.0 2.3 2 1 0 2 2 2 0 Glutamine amidotransferase domain Flavoprotein PF02441.14 CCF51682.1 - 1.5e-36 124.9 0.0 2.8e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein VPS9 PF02204.13 CCF51682.1 - 1.5e-26 92.4 0.0 3.1e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Cyclase PF04199.8 CCF51682.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative cyclase FAD_binding_7 PF03441.9 CCF51683.1 - 1.4e-54 185.2 1.9 1.9e-54 184.7 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CCF51683.1 - 3.5e-23 82.1 0.0 8.7e-23 80.8 0.0 1.6 1 1 0 1 1 1 1 DNA photolyase HSP70 PF00012.15 CCF51684.1 - 6e-159 529.7 0.1 6e-159 529.7 0.1 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCF51684.1 - 4e-09 35.5 0.0 1.2e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCF51684.1 - 0.022 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Aldedh PF00171.17 CCF51685.1 - 4e-12 45.2 4.0 2.3e-11 42.7 1.5 2.6 2 1 0 2 2 2 1 Aldehyde dehydrogenase family Ribosomal_L34 PF00468.12 CCF51686.1 - 4.1e-15 55.1 8.4 6.8e-15 54.4 5.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 ATP-synt_C PF00137.16 CCF51687.1 - 2.3e-28 97.8 33.3 1.4e-17 63.3 8.5 2.6 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 CCF51687.1 - 0.63 9.6 7.1 0.76 9.4 2.9 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Dus PF01207.12 CCF51689.1 - 1.3e-46 158.9 0.0 2.3e-44 151.5 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Phospho_p8 PF10195.4 CCF51689.1 - 0.99 9.3 4.1 1.8 8.4 1.5 2.3 2 0 0 2 2 2 0 DNA-binding nuclear phosphoprotein p8 DUF155 PF02582.9 CCF51690.1 - 6.4e-52 175.9 0.0 1.1e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Nucleoplasmin PF03066.10 CCF51690.1 - 0.88 9.0 12.9 2 7.8 8.9 1.6 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCF51690.1 - 1.5 8.0 7.1 2.9 7.0 4.9 1.4 1 0 0 1 1 1 0 NOA36 protein IFT57 PF10498.4 CCF51690.1 - 2.8 6.5 6.0 5.1 5.7 4.1 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MPLKIP PF15502.1 CCF51691.1 - 5.2 7.7 10.3 2.2 8.9 5.2 1.9 1 1 0 1 1 1 0 M-phase-specific PLK1-interacting protein Prenyltrans PF00432.16 CCF51692.1 - 2.8e-30 103.5 10.1 1.7e-09 37.0 0.0 7.1 7 0 0 7 7 7 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCF51692.1 - 3.9e-26 91.1 2.2 1.1e-12 47.8 0.1 5.7 4 2 1 5 5 5 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 CCF51692.1 - 2.3e-23 82.7 6.2 4.5e-16 59.2 0.1 5.4 2 2 4 6 6 6 5 Prenyltransferase-like A2M_comp PF07678.9 CCF51692.1 - 2.5e-08 33.4 1.4 5e-05 22.6 0.1 3.4 2 1 1 3 3 3 2 A-macroglobulin complement component Pec_lyase PF09492.5 CCF51692.1 - 1.5e-07 30.9 0.6 0.014 14.5 0.0 4.6 2 1 1 4 4 4 3 Pectic acid lyase DUF1242 PF06842.7 CCF51693.1 - 5.7e-18 64.1 0.5 7.4e-18 63.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) GST_N PF02798.15 CCF51694.1 - 4.4e-12 45.9 0.0 1.1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCF51694.1 - 7e-11 42.1 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF51694.1 - 2.3e-09 37.0 0.0 7.7e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCF51694.1 - 5.6e-09 35.8 0.0 6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCF51694.1 - 3.7e-08 33.2 0.2 1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF51694.1 - 0.0015 18.9 0.2 0.0042 17.5 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Thioredoxin_8 PF13905.1 CCF51694.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Sua5_yciO_yrdC PF01300.13 CCF51695.1 - 1.2e-48 164.6 0.0 8.9e-48 161.8 0.0 2.1 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CCF51695.1 - 3.5e-24 85.2 0.0 1.9e-23 82.8 0.0 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ribonuc_L-PSP PF01042.16 CCF51695.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP TMEM154 PF15102.1 CCF51696.1 - 0.00098 18.8 0.9 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family COX14 PF14880.1 CCF51696.1 - 0.0021 17.6 0.1 0.0053 16.3 0.1 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF456 PF04306.8 CCF51696.1 - 0.0085 16.1 0.3 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) EphA2_TM PF14575.1 CCF51696.1 - 0.015 15.6 0.0 0.015 15.6 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.2 CCF51696.1 - 0.038 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity GRP PF07172.6 CCF51696.1 - 0.055 13.9 7.1 0.57 10.6 0.0 2.7 3 0 0 3 3 2 0 Glycine rich protein family Herpes_UL37_2 PF07413.6 CCF51696.1 - 0.089 11.5 0.2 0.18 10.5 0.2 1.5 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 P12 PF12669.2 CCF51696.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.8 2 0 0 2 2 1 0 Virus attachment protein p12 family DUF2207 PF09972.4 CCF51696.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.15 CCF51696.1 - 0.19 11.3 1.2 0.4 10.3 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain YajC PF02699.10 CCF51696.1 - 0.51 10.0 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit DUF1183 PF06682.7 CCF51696.1 - 4.3 6.8 10.6 36 3.8 6.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Pkinase PF00069.20 CCF51697.1 - 1e-67 228.0 0.0 1.5e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51697.1 - 1.9e-56 191.0 0.0 2.8e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 CCF51697.1 - 8.5e-07 28.6 8.8 1.7e-06 27.6 6.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 CCF51697.1 - 5.3e-06 26.4 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Kinase-like PF14531.1 CCF51697.1 - 0.0003 19.8 0.0 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like CAMSAP_CH PF11971.3 CCF51697.1 - 0.00091 18.8 0.0 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain CDC24 PF06395.6 CCF51697.1 - 0.0011 19.0 0.0 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin RIO1 PF01163.17 CCF51697.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 CCF51697.1 - 0.0091 14.8 0.2 0.015 14.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Prok-RING_1 PF14446.1 CCF51697.1 - 0.056 13.1 9.2 0.12 12.1 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 CCF51697.1 - 1.2 8.8 9.8 3.2 7.5 6.8 1.7 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 CCF51698.1 - 6e-47 155.9 17.4 9.5e-10 37.9 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CCF51698.1 - 0.0018 18.0 7.7 0.086 12.5 0.3 3.7 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term EamA PF00892.15 CCF51699.1 - 2.8e-24 85.5 34.7 3.2e-13 49.8 6.9 3.2 2 2 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 CCF51699.1 - 8.4e-07 29.1 5.8 8.4e-07 29.1 4.0 3.4 2 2 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 CCF51699.1 - 2.5 7.7 20.8 1.2 8.7 4.1 3.1 2 2 0 2 2 2 0 Triose-phosphate Transporter family Fungal_trans PF04082.13 CCF51700.1 - 2.3e-13 49.6 0.3 5.7e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF51700.1 - 1.5e-06 28.0 9.5 3e-06 27.0 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 CCF51701.1 - 5.9e-11 41.3 10.3 4.7e-06 25.8 0.9 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCF51701.1 - 1.5e-07 30.8 10.6 8.6e-05 22.0 0.6 3.9 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CCF51701.1 - 0.023 13.2 0.1 0.03 12.8 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase Sec1 PF00995.18 CCF51702.1 - 7.5e-150 500.2 0.0 8.6e-150 500.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3349 PF11829.3 CCF51702.1 - 0.024 15.0 0.7 5 7.6 0.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) RVT_2 PF07727.9 CCF51703.1 - 4.1e-44 150.4 0.0 4.6e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF51704.1 - 0.0029 16.9 0.1 0.0055 16.0 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF51705.1 - 3.9e-14 52.7 0.0 7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF51705.1 - 5.5e-10 38.7 0.8 1.1e-09 37.8 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Hexapep PF00132.19 CCF51707.1 - 5.9e-06 25.5 6.1 0.074 12.5 0.3 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCF51707.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CCF51707.1 - 0.0067 15.7 0.0 0.07 12.4 0.1 2.3 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 CCF51707.1 - 0.008 15.7 9.1 0.42 10.2 6.3 2.8 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCF51707.1 - 0.016 14.8 0.2 0.052 13.1 0.0 1.8 2 0 0 2 2 2 0 Cytidylyltransferase Aa_trans PF01490.13 CCF51708.1 - 2.6e-72 243.5 18.8 2.6e-72 243.5 13.0 1.8 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCF51708.1 - 7.3e-06 25.0 13.1 7.3e-06 25.0 9.1 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1180 PF06679.7 CCF51709.1 - 0.025 14.4 0.3 0.025 14.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF1980 PF09323.5 CCF51709.1 - 0.04 13.6 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_M56 PF05569.6 CCF51709.1 - 0.26 10.2 0.7 0.37 9.7 0.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF751 PF05421.6 CCF51709.1 - 3.8 7.8 5.2 0.71 10.2 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF751) DDHD PF02862.12 CCF51710.1 - 2.4e-41 142.0 0.0 2.4e-41 142.0 0.0 3.4 3 0 0 3 3 3 1 DDHD domain Abhydrolase_6 PF12697.2 CCF51710.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF51710.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kri1_C PF12936.2 CCF51710.1 - 0.2 11.6 4.5 0.064 13.2 0.4 2.2 2 0 0 2 2 2 0 KRI1-like family C-terminal PACT_coil_coil PF10495.4 CCF51711.1 - 3.3e-14 52.5 1.9 1.7e-13 50.2 1.3 2.4 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.10 CCF51711.1 - 0.0025 17.8 18.4 0.0025 17.8 12.8 8.1 4 2 3 8 8 8 1 Fez1 AAA_13 PF13166.1 CCF51711.1 - 0.042 12.3 77.8 0.094 11.1 12.1 4.5 3 1 1 4 4 4 0 AAA domain DUF4250 PF14056.1 CCF51711.1 - 0.075 12.7 3.5 0.65 9.7 2.4 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Zn_clus PF00172.13 CCF51713.1 - 1e-06 28.5 9.4 1e-06 28.5 6.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 CCF51713.1 - 4.9e-05 23.4 0.2 0.00032 20.8 0.0 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF51713.1 - 0.00034 20.7 1.5 0.00072 19.7 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger TAF4 PF05236.9 CCF51713.1 - 0.32 10.2 1.8 5.8 6.0 0.1 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family ABC_membrane PF00664.18 CCF51714.1 - 4.6e-44 150.8 2.6 6.6e-44 150.3 1.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCF51714.1 - 1.2e-33 116.3 0.0 2.4e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCF51714.1 - 0.00013 21.2 0.0 0.0023 17.2 0.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF51714.1 - 0.00014 21.9 0.0 0.011 15.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain ABC_ATPase PF09818.4 CCF51714.1 - 0.0011 17.6 0.1 0.0017 16.9 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCF51714.1 - 0.02 14.3 0.1 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain CLASP_N PF12348.3 CCF51715.1 - 1.7e-28 99.5 0.0 2.8e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 CLASP N terminal DPBB_1 PF03330.13 CCF51717.1 - 4.5e-06 26.5 1.5 5.7e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Sporozoite_P67 PF05642.6 CCF51717.1 - 0.11 10.3 20.9 0.14 9.9 14.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SAPS PF04499.10 CCF51717.1 - 0.83 8.2 11.3 1.2 7.7 7.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 CCF51717.1 - 1.1 7.2 14.9 1.6 6.6 10.3 1.4 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 CCF51717.1 - 2.4 8.4 8.2 5.2 7.3 5.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Plasmodium_Vir PF05795.6 CCF51717.1 - 2.5 7.2 12.0 4.1 6.5 8.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mem_trans PF03547.13 CCF51717.1 - 3.4 5.8 4.6 4.6 5.4 3.2 1.3 1 0 0 1 1 1 0 Membrane transport protein TFIIF_alpha PF05793.7 CCF51717.1 - 3.8 5.7 27.1 5.1 5.3 18.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 CCF51717.1 - 4.3 5.1 19.1 5.1 4.8 13.3 1.2 1 0 0 1 1 1 0 Nop14-like family CBF PF03914.12 CCF51718.1 - 1.7e-45 154.4 1.5 4.8e-45 152.9 0.1 2.6 2 0 0 2 2 2 1 CBF/Mak21 family RVT_2 PF07727.9 CCF51719.1 - 0.0032 16.4 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPP1 PF05630.6 CCF51719.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Peptidase_C15 PF01470.12 CCF51720.1 - 9.4e-11 41.9 0.0 0.0002 21.2 0.0 2.8 3 1 0 3 3 3 2 Pyroglutamyl peptidase rve PF00665.21 CCF51721.1 - 3.8e-17 62.5 0.0 7.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF51721.1 - 0.00036 19.9 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain FLYWCH PF04500.11 CCF51723.1 - 0.069 13.0 2.3 0.11 12.4 1.6 1.3 1 0 0 1 1 1 0 FLYWCH zinc finger domain DUF2946 PF11162.3 CCF51723.1 - 0.098 12.8 0.7 0.12 12.5 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) RVT_2 PF07727.9 CCF51724.1 - 1.3e-42 145.5 0.1 1.6e-30 105.8 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 CCF51725.1 - 4.9e-65 219.2 0.0 7e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51725.1 - 1.3e-45 155.5 0.0 1.9e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51725.1 - 2.4e-08 33.2 0.0 8.4e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCF51725.1 - 0.00021 21.0 0.0 0.22 11.2 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family CTP_transf_1 PF01148.15 CCF51726.1 - 4.8e-71 239.4 25.3 1.5e-70 237.8 17.5 1.8 1 1 0 1 1 1 1 Cytidylyltransferase family TFIIA PF03153.8 CCF51726.1 - 0.044 13.6 18.2 0.061 13.2 12.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX2_TM PF02790.10 CCF51726.1 - 0.12 12.3 3.8 0.57 10.1 0.1 2.9 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain SOG2 PF10428.4 CCF51726.1 - 0.38 9.3 18.1 0.73 8.4 12.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF912 PF06024.7 CCF51726.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RVT_2 PF07727.9 CCF51727.1 - 1.6e-05 24.0 0.1 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fork_head PF00250.13 CCF51729.1 - 1.5e-10 40.9 0.1 1.5e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Fork head domain UCH PF00443.24 CCF51730.1 - 1.8e-47 161.7 0.0 2.2e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF51730.1 - 8.5e-18 64.8 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DnaJ-X PF14308.1 CCF51731.1 - 1.7e-43 148.2 2.0 1.7e-43 148.2 1.4 1.7 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCF51731.1 - 3e-26 90.9 1.8 6.7e-26 89.8 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain Las1 PF04031.8 CCF51732.1 - 1.4e-46 157.9 0.0 2.8e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Las1-like DUF3829 PF12889.2 CCF51732.1 - 0.0018 17.5 0.3 0.0032 16.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) BUD22 PF09073.5 CCF51733.1 - 0.62 9.0 55.9 0.91 8.5 38.8 1.3 1 0 0 1 1 1 0 BUD22 Microtub_bind PF13931.1 CCF51735.1 - 0.37 10.9 6.2 0.59 10.2 3.6 1.9 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding Pet127 PF08634.5 CCF51736.1 - 7.9e-114 379.4 0.0 1.3e-113 378.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Ribosomal_L6e PF01159.14 CCF51737.1 - 2.2e-38 130.8 1.5 2.2e-38 130.8 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e RFPL3_antisense PF10489.4 CCF51738.1 - 0.15 11.8 0.4 0.22 11.2 0.3 1.2 1 0 0 1 1 1 0 Ret finger protein-like 3 antisense Thi4 PF01946.12 CCF51739.1 - 1.2e-91 305.9 0.1 1.5e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCF51739.1 - 7.6e-09 34.9 1.0 4.4e-08 32.4 0.6 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF51739.1 - 1.4e-07 31.4 0.1 3.8e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CCF51739.1 - 1.4e-06 27.4 0.3 9.6e-06 24.7 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCF51739.1 - 7.1e-06 25.8 0.0 9.5e-05 22.2 0.1 2.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CCF51739.1 - 2.4e-05 23.3 1.7 0.00023 20.1 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CCF51739.1 - 9.4e-05 22.3 0.2 0.00022 21.1 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF51739.1 - 0.0012 17.4 0.2 0.0018 16.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CCF51739.1 - 0.0015 18.5 0.3 0.0048 16.9 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCF51739.1 - 0.0082 15.0 0.0 0.04 12.7 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 CCF51739.1 - 0.02 13.5 0.2 0.03 12.9 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.2 CCF51739.1 - 0.041 12.9 1.0 0.082 11.9 0.7 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Xpo1 PF08389.7 CCF51740.1 - 2.9e-17 62.9 9.2 2.9e-15 56.4 0.1 4.7 5 0 0 5 5 5 2 Exportin 1-like protein HEAT PF02985.17 CCF51740.1 - 0.42 10.8 3.7 36 4.8 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 CCF51740.1 - 0.83 10.2 5.5 0.73 10.4 0.1 3.6 3 0 0 3 3 3 0 HEAT-like repeat rve PF00665.21 CCF51741.1 - 1.6e-12 47.5 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF51741.1 - 1.4e-07 31.0 0.4 3.7e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCF51742.1 - 0.0074 16.1 0.2 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CCF51742.1 - 0.066 12.8 0.4 0.18 11.5 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle HSF_DNA-bind PF00447.12 CCF51743.1 - 1.8e-20 73.0 0.0 3.8e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Nucleoplasmin PF03066.10 CCF51743.1 - 0.091 12.2 10.7 0.11 11.9 1.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin RXT2_N PF08595.6 CCF51743.1 - 7.6 6.3 12.1 3.5 7.4 1.8 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal PRP1_N PF06424.7 CCF51744.1 - 2.8e-44 150.6 2.9 7.2e-44 149.3 2.0 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CCF51744.1 - 4e-19 67.3 18.2 0.15 12.7 0.0 11.9 9 4 3 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCF51744.1 - 7e-12 45.5 9.9 0.3 11.4 0.0 8.4 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCF51744.1 - 1e-07 32.4 4.0 0.11 13.1 0.0 7.3 6 2 1 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF51744.1 - 1.7e-06 27.5 1.6 5.3 6.7 0.0 6.7 7 1 1 8 8 8 2 TPR repeat TPR_9 PF13371.1 CCF51744.1 - 0.028 14.2 0.1 9.3 6.1 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.3 CCF51744.1 - 1.6 7.3 8.9 0.67 8.6 0.1 3.9 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 DER1 PF04511.10 CCF51745.1 - 4.5e-49 166.6 4.9 5e-49 166.4 3.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF962 PF06127.6 CCF51746.1 - 4.4e-24 84.2 0.0 8.9e-24 83.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Nt_Gln_amidase PF09764.4 CCF51747.1 - 8.4e-37 126.2 3.3 5.5e-34 117.0 2.3 3.0 1 1 0 1 1 1 1 N-terminal glutamine amidase KAT11 PF08214.6 CCF51748.1 - 1.1e-31 110.1 0.4 2e-24 86.3 0.0 2.8 3 1 0 3 3 3 2 Histone acetylation protein zf-Apc11 PF12861.2 CCF51749.1 - 2e-32 110.8 11.4 2.7e-32 110.4 7.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCF51749.1 - 1.3e-28 98.8 11.3 1.6e-28 98.5 7.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCF51749.1 - 7.1e-08 32.1 16.3 2.5e-07 30.4 11.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF51749.1 - 0.00026 20.9 12.0 0.01 15.8 7.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF51749.1 - 0.00058 19.4 13.4 0.0067 16.0 9.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF51749.1 - 0.00088 18.8 12.4 0.0039 16.8 8.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF51749.1 - 0.03 14.0 14.7 0.25 11.1 10.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 CCF51749.1 - 0.61 9.7 16.5 4.1 7.0 8.6 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CCF51749.1 - 0.7 9.8 13.9 2.5 8.1 9.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CCF51749.1 - 0.95 9.4 9.4 0.61 10.1 5.5 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain RRN7 PF11781.3 CCF51749.1 - 1.6 8.2 8.6 9.9 5.7 2.6 2.9 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-HC5HC2H PF13771.1 CCF51749.1 - 2.8 8.1 11.0 1.6 8.9 6.1 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 CCF51749.1 - 9.2 6.3 13.4 30 4.7 9.3 2.0 1 1 0 1 1 1 0 RING-like domain Na_H_Exchanger PF00999.16 CCF51750.1 - 3.1e-60 203.7 21.0 3.9e-60 203.3 14.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 CCF51750.1 - 0.059 13.3 0.7 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 YrhC-like protein PIG-F PF06699.6 CCF51751.1 - 1.9e-13 50.7 2.9 1e-05 25.5 0.0 2.4 2 1 0 2 2 2 2 GPI biosynthesis protein family Pig-F Pex14_N PF04695.8 CCF51751.1 - 0.055 13.5 3.5 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MIP-T3 PF10243.4 CCF51751.1 - 2.7 6.3 10.1 4.5 5.6 7.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ish1 PF10281.4 CCF51752.1 - 3.9e-52 173.8 27.2 2.4e-11 43.4 0.1 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 CCF51752.1 - 0.052 13.0 0.0 19 4.9 0.0 3.9 4 0 0 4 4 4 0 SAP domain YtxH PF12732.2 CCF51752.1 - 0.55 10.6 0.1 0.55 10.6 0.1 5.0 2 1 0 2 2 2 0 YtxH-like protein UPF0183 PF03676.9 CCF51753.1 - 3.7e-27 94.9 1.2 1e-14 53.9 1.0 5.8 5 1 0 5 5 5 3 Uncharacterised protein family (UPF0183) Syntaxin PF00804.20 CCF51754.1 - 0.0073 16.4 8.2 0.0099 16.0 3.1 2.2 2 0 0 2 2 2 1 Syntaxin HisKA PF00512.20 CCF51754.1 - 0.0077 16.2 1.0 2.3 8.2 0.1 2.5 1 1 1 2 2 2 2 His Kinase A (phospho-acceptor) domain DUF1664 PF07889.7 CCF51754.1 - 0.0079 15.9 0.5 0.014 15.2 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) FemAB PF02388.11 CCF51754.1 - 0.04 12.6 0.6 0.053 12.1 0.5 1.3 1 0 0 1 1 1 0 FemAB family DUF677 PF05055.7 CCF51754.1 - 0.04 12.5 0.7 0.072 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF883 PF05957.8 CCF51754.1 - 0.11 12.9 7.6 1.2 9.5 0.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3829 PF12889.2 CCF51754.1 - 0.16 11.1 4.8 0.71 9.0 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) CHASE3 PF05227.8 CCF51754.1 - 0.2 11.3 3.9 0.13 11.9 0.9 2.0 2 1 0 2 2 2 0 CHASE3 domain Prominin PF05478.6 CCF51754.1 - 0.38 8.2 4.0 0.18 9.3 0.6 1.8 2 0 0 2 2 2 0 Prominin zf-C4H2 PF10146.4 CCF51754.1 - 0.63 10.0 5.8 0.069 13.1 1.1 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Syntaxin-6_N PF09177.6 CCF51754.1 - 1.4 9.4 5.1 4.6 7.7 1.7 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlgN PF05130.7 CCF51754.1 - 1.5 9.0 7.0 0.43 10.8 2.5 1.7 2 0 0 2 2 2 0 FlgN protein G_glu_transpept PF01019.16 CCF51755.1 - 2.4e-154 514.5 0.0 6.2e-154 513.2 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase RRM_1 PF00076.17 CCF51756.1 - 7.6e-44 147.2 0.0 2e-17 62.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51756.1 - 5.5e-38 128.7 0.0 1.6e-13 50.4 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51756.1 - 9.5e-21 73.4 0.0 3.9e-08 33.0 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF51756.1 - 0.00066 19.4 0.0 0.22 11.4 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCF51756.1 - 0.0009 18.9 0.0 5.6 6.8 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 CCF51756.1 - 0.03 14.3 0.3 0.29 11.1 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain CUE PF02845.11 CCF51758.1 - 9.9e-11 40.9 0.0 1.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 CCF51758.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) RhoGEF PF00621.15 CCF51759.1 - 7.1e-19 68.3 0.0 1.1e-14 54.6 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain PUL PF08324.6 CCF51759.1 - 0.32 9.7 0.0 0.54 9.0 0.0 1.3 1 0 0 1 1 1 0 PUL domain SoxE PF06525.6 CCF51760.1 - 0.56 9.4 2.9 1.1 8.4 2.0 1.4 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Malic_M PF03949.10 CCF51761.1 - 5.7e-80 268.5 0.0 7.9e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCF51761.1 - 2.9e-67 225.8 0.0 4.3e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Catalase PF00199.14 CCF51763.1 - 8.1e-160 531.6 0.1 1e-159 531.3 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCF51763.1 - 4.8e-16 58.3 0.0 1.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DSPc PF00782.15 CCF51764.1 - 6.2e-29 100.2 0.0 1e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 CCF51764.1 - 0.0022 17.3 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCF51764.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCF51764.1 - 0.0092 16.2 0.0 0.029 14.6 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4597 PF15366.1 CCF51764.1 - 0.14 11.7 1.9 0.48 10.0 0.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4597) SERTA PF06031.8 CCF51766.1 - 0.00058 19.0 0.1 0.0022 17.2 0.0 1.9 2 0 0 2 2 2 1 SERTA motif Alpha-amylase PF00128.19 CCF51769.1 - 5.8e-28 98.1 0.7 1.5e-23 83.6 0.0 2.6 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 CCF51769.1 - 7.2e-09 33.9 0.9 0.015 13.1 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 CCF51769.1 - 0.00071 19.4 0.2 0.0025 17.6 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Alpha-amylase_C PF02806.13 CCF51769.1 - 0.017 15.2 0.1 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Mitochondr_Som1 PF11093.3 CCF51770.1 - 0.00028 20.6 0.4 0.00051 19.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PHD PF00628.24 CCF51772.1 - 1.4e-07 31.0 10.3 2.8e-07 30.0 7.2 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CCF51772.1 - 0.0084 15.8 3.8 0.016 14.9 2.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 CCF51772.1 - 0.28 11.3 2.7 0.68 10.1 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-CSL PF05207.8 CCF51772.1 - 0.57 9.7 5.0 1.8 8.1 3.5 1.8 1 0 0 1 1 1 0 CSL zinc finger DUF4206 PF13901.1 CCF51772.1 - 0.93 9.0 5.6 2 7.9 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) SAP30_Sin3_bdg PF13867.1 CCF51773.1 - 0.0019 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Lyase_8_N PF08124.6 CCF51774.1 - 0.067 12.0 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Mg_trans_NIPA PF05653.9 CCF51775.1 - 4.7e-63 212.9 1.8 1.2e-59 201.7 0.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CCF51775.1 - 1.3e-06 28.5 10.5 4.9e-05 23.4 0.1 3.1 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 CCF51775.1 - 0.00027 20.9 3.5 0.00027 20.9 2.4 3.7 3 1 1 4 4 4 1 EamA-like transporter family Oxidored_q6 PF01058.17 CCF51775.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Shisa PF13908.1 CCF51775.1 - 0.45 10.6 0.0 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SpoIIIAH PF12685.2 CCF51775.1 - 0.83 9.1 3.8 0.92 8.9 0.7 2.2 3 0 0 3 3 3 0 SpoIIIAH-like protein Coprogen_oxidas PF01218.13 CCF51776.1 - 5.1e-110 366.6 1.0 6e-37 126.7 0.0 3.1 3 0 0 3 3 3 3 Coproporphyrinogen III oxidase Lactonase PF10282.4 CCF51778.1 - 1e-70 238.5 0.6 1.2e-70 238.3 0.4 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller YmzC PF14157.1 CCF51778.1 - 0.025 14.4 0.0 26 4.7 0.0 3.4 3 0 0 3 3 3 0 YmzC-like protein Nup54 PF13874.1 CCF51779.1 - 9.7e-28 96.6 3.3 5.9e-27 94.0 0.7 2.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CCF51779.1 - 0.11 12.7 100.9 0.024 14.8 30.6 3.4 2 1 1 3 3 3 0 Nucleoporin FG repeat region DUF1748 PF08520.5 CCF51780.1 - 7.9e-28 95.9 0.0 8.9e-28 95.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) BAR PF03114.13 CCF51782.1 - 2.8e-19 69.5 0.1 3.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 BAR domain IncA PF04156.9 CCF51782.1 - 0.054 13.0 2.1 0.094 12.3 1.4 1.3 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 CCF51782.1 - 0.27 8.5 6.3 0.37 8.0 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 CCF51782.1 - 0.47 9.4 3.6 0.79 8.7 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pex14_N PF04695.8 CCF51783.1 - 4.4e-32 110.9 3.1 1.3e-30 106.2 0.1 3.6 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CCF51783.1 - 3.7e-05 23.4 2.0 7.4e-05 22.4 1.4 1.4 1 0 0 1 1 1 1 IncA protein DUF948 PF06103.6 CCF51783.1 - 0.0019 18.0 2.5 0.26 11.1 1.4 2.4 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CCF51783.1 - 0.0069 15.0 2.5 0.014 14.0 1.7 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.3 CCF51783.1 - 0.0079 13.6 4.2 0.011 13.1 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1664 PF07889.7 CCF51783.1 - 0.016 14.9 4.8 0.025 14.3 2.2 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF4631 PF15450.1 CCF51783.1 - 0.018 13.3 4.2 0.028 12.6 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) Baculo_PEP_C PF04513.7 CCF51783.1 - 0.045 13.5 1.1 0.083 12.7 0.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 CCF51783.1 - 0.051 13.7 3.8 0.063 13.4 0.6 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vac_Fusion PF02346.11 CCF51783.1 - 0.078 12.4 0.2 0.34 10.3 0.1 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Reo_sigmaC PF04582.7 CCF51783.1 - 0.086 12.0 1.9 0.24 10.5 1.3 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Spectrin PF00435.16 CCF51783.1 - 0.09 13.0 3.4 0.098 12.9 0.8 2.1 2 0 0 2 2 2 0 Spectrin repeat Enkurin PF13864.1 CCF51783.1 - 0.093 12.9 2.5 0.11 12.7 0.6 1.9 1 1 1 2 2 2 0 Calmodulin-binding Mod_r PF07200.8 CCF51783.1 - 0.11 12.4 4.7 0.065 13.1 1.6 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.7 CCF51783.1 - 0.12 10.5 3.4 0.086 11.0 0.5 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2317 PF10079.4 CCF51783.1 - 0.13 10.8 1.9 0.18 10.3 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Myosin_tail_1 PF01576.14 CCF51783.1 - 0.13 9.9 9.5 0.3 8.7 6.6 1.4 1 1 0 1 1 1 0 Myosin tail APG17 PF04108.7 CCF51783.1 - 0.17 10.6 3.4 0.35 9.6 2.4 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 HALZ PF02183.13 CCF51783.1 - 0.18 11.5 6.1 0.35 10.6 0.5 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper FUSC PF04632.7 CCF51783.1 - 0.2 10.0 0.0 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.7 CCF51783.1 - 0.25 11.1 3.8 1.1 9.0 2.6 2.0 1 1 0 1 1 1 0 Laminin Domain II APG6 PF04111.7 CCF51783.1 - 0.27 10.2 5.5 0.44 9.5 3.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HisKA_3 PF07730.8 CCF51783.1 - 0.3 11.4 1.4 0.98 9.8 0.5 2.2 1 1 1 2 2 2 0 Histidine kinase TPR_MLP1_2 PF07926.7 CCF51783.1 - 0.31 10.7 8.2 0.3 10.8 2.2 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 CCF51783.1 - 0.41 10.0 5.1 1.2 8.5 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Atg14 PF10186.4 CCF51783.1 - 0.47 9.3 2.8 0.72 8.7 2.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec20 PF03908.8 CCF51783.1 - 0.54 10.0 3.0 5 6.8 0.2 2.3 2 0 0 2 2 2 0 Sec20 TBPIP PF07106.8 CCF51783.1 - 0.64 9.5 7.3 0.83 9.1 1.9 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) COG2 PF06148.6 CCF51783.1 - 0.7 9.7 6.1 0.65 9.8 1.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.13 CCF51783.1 - 0.74 9.2 6.8 1.8 8.0 4.7 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3829 PF12889.2 CCF51783.1 - 1.1 8.4 5.9 0.74 8.9 1.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) DUF3583 PF12126.3 CCF51783.1 - 2.3 7.1 7.9 0.044 12.8 0.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3583) ADIP PF11559.3 CCF51783.1 - 2.3 8.0 7.4 0.45 10.4 1.8 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.5 CCF51783.1 - 3.1 7.8 10.6 3.1 7.8 2.7 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil Syntaxin PF00804.20 CCF51783.1 - 6.5 6.9 9.3 3.1 8.0 3.7 2.4 2 1 0 2 2 1 0 Syntaxin RNA_pol_L_2 PF13656.1 CCF51784.1 - 2.2e-26 91.0 0.0 3e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCF51784.1 - 1.4e-13 49.7 0.0 1.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MBOAT_2 PF13813.1 CCF51785.1 - 8.7e-12 44.9 3.5 8.7e-12 44.9 2.4 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Myb_DNA-binding PF00249.26 CCF51786.1 - 1e-16 60.7 0.0 7.6e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCF51786.1 - 2.4e-15 56.3 0.0 1.8e-07 31.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Med15 PF09606.5 CCF51786.1 - 1.4e-05 23.5 67.0 1.4e-05 23.5 46.4 4.0 4 0 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CCF51786.1 - 0.093 12.1 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 DHHC palmitoyltransferase OATP PF03137.15 CCF51786.1 - 3.3 5.6 10.3 5.4 4.9 7.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cellulose_synt PF03552.9 CCF51786.1 - 5.8 5.0 5.6 9.6 4.3 3.9 1.2 1 0 0 1 1 1 0 Cellulose synthase CMS1 PF14617.1 CCF51786.1 - 9.4 5.2 12.3 19 4.1 8.6 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2392 PF10288.4 CCF51787.1 - 3.5e-20 72.3 0.0 7.4e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Peptidase_M22 PF00814.20 CCF51788.1 - 1.9e-78 263.6 0.0 1.5e-77 260.7 0.0 1.9 1 1 0 1 1 1 1 Glycoprotease family APG5 PF04106.7 CCF51789.1 - 2.6e-44 151.0 0.0 6.8e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 zf-CCHC PF00098.18 CCF51790.1 - 3.1e-06 26.8 1.7 7.2e-06 25.6 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle TFIID_20kDa PF03847.8 CCF51791.1 - 7.4e-30 103.0 0.6 1.2e-29 102.3 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBF PF03914.12 CCF51793.1 - 4.1e-40 136.9 0.0 4.1e-40 136.9 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family Pox_Ag35 PF03286.9 CCF51793.1 - 0.72 9.3 15.2 1.5 8.3 4.3 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Pkinase PF00069.20 CCF51794.1 - 1.3e-70 237.5 0.0 1.6e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51794.1 - 5.9e-29 100.9 0.1 1.4e-28 99.7 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51794.1 - 0.00011 21.2 0.0 0.0014 17.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCF51794.1 - 0.034 13.2 0.2 0.066 12.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCF51794.1 - 0.061 12.6 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glucodextran_N PF09137.6 CCF51795.1 - 0.0036 16.5 0.3 0.0043 16.3 0.2 1.1 1 0 0 1 1 1 1 Glucodextranase, domain N Tyr_Deacylase PF02580.11 CCF51797.1 - 2.2e-40 137.9 0.0 1.6e-25 89.7 0.0 2.1 2 0 0 2 2 2 2 D-Tyr-tRNA(Tyr) deacylase DUF4112 PF13430.1 CCF51799.1 - 1e-27 96.1 0.1 1.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.27 CCF51800.1 - 1.2e-12 47.1 7.2 2.2e-06 27.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CCF51800.1 - 0.012 15.9 6.2 13 6.2 0.1 5.2 5 1 0 5 5 5 0 PQQ-like domain Syntaxin_2 PF14523.1 CCF51801.1 - 5.5e-18 64.8 1.8 5.5e-18 64.8 1.2 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CCF51801.1 - 7.4e-17 60.7 4.9 2.9e-16 58.8 1.1 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCF51801.1 - 0.00031 20.8 3.2 0.00031 20.8 2.2 3.1 1 1 1 2 2 2 1 Syntaxin MCPsignal PF00015.16 CCF51801.1 - 0.014 14.9 3.7 0.27 10.7 0.1 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4355 PF14265.1 CCF51801.1 - 0.26 11.2 10.6 0.04 13.8 4.2 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4355) FlaC_arch PF05377.6 CCF51801.1 - 5.1 7.0 6.7 12 5.8 0.1 3.6 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Ribosomal_S4 PF00163.14 CCF51802.1 - 6.3e-12 45.7 1.0 9.4e-12 45.1 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCF51802.1 - 1.3e-10 40.5 0.0 2.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain UCH PF00443.24 CCF51803.1 - 7.2e-46 156.4 0.0 8.9e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF51803.1 - 2.2e-22 79.8 0.1 1.6e-21 77.0 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCF51803.1 - 1.3e-07 30.8 0.0 2.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCF51803.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain GTP_EFTU PF00009.22 CCF51805.1 - 8.6e-34 116.6 1.4 5.6e-32 110.6 0.9 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCF51805.1 - 2.3e-23 82.1 0.3 4.6e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCF51805.1 - 1e-09 38.3 0.2 0.00013 22.0 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF51805.1 - 1.5e-05 24.8 0.1 3.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF51805.1 - 0.004 16.4 0.1 0.018 14.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 CCF51805.1 - 0.014 15.1 0.5 0.033 13.9 0.3 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CCF51805.1 - 0.089 13.2 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 CCF51805.1 - 0.11 11.6 0.1 0.34 10.0 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCF51805.1 - 0.13 11.7 0.7 3.9 6.9 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DOG1 PF14144.1 CCF51806.1 - 0.39 10.7 6.1 1.6 8.7 0.6 3.2 2 0 0 2 2 2 0 Seed dormancy control Reo_sigmaC PF04582.7 CCF51806.1 - 7.1 5.7 21.9 0.19 10.9 4.6 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein RRM_1 PF00076.17 CCF51807.1 - 6e-76 250.0 0.7 8.9e-19 66.8 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51807.1 - 1.1e-71 236.7 0.4 1.5e-16 60.1 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51807.1 - 3.6e-40 135.6 0.0 5.8e-08 32.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 CCF51807.1 - 5.6e-05 23.0 0.0 0.96 9.4 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif 2 Limkain-b1 PF11608.3 CCF51807.1 - 0.00035 20.2 1.0 0.11 12.2 0.0 4.4 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 CCF51807.1 - 0.00078 19.1 0.0 2.4 7.9 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif DUF4632 PF15451.1 CCF51807.1 - 1.1 9.2 9.9 11 6.0 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) DUF89 PF01937.14 CCF51808.1 - 5.5e-109 364.2 0.1 6.3e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 polyprenyl_synt PF00348.12 CCF51808.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase PDDEXK_1 PF12705.2 CCF51809.1 - 0.0098 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily 2OG-FeII_Oxy_2 PF13532.1 CCF51810.1 - 3.8e-15 56.2 0.0 7e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCF51810.1 - 8.6e-05 22.7 0.0 0.026 14.8 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily RINGv PF12906.2 CCF51811.1 - 8.7e-08 32.0 5.2 1.8e-07 31.0 3.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-rbx1 PF12678.2 CCF51811.1 - 0.0041 17.1 3.8 0.0086 16.1 2.2 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCF51811.1 - 0.05 13.4 11.1 0.11 12.3 6.8 2.3 2 1 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 CCF51811.1 - 0.054 13.4 3.0 0.1 12.5 2.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCF51811.1 - 0.29 10.7 2.8 0.6 9.7 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CCF51811.1 - 0.83 9.3 5.2 1.8 8.3 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF51811.1 - 5.2 6.8 6.5 14 5.4 4.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SRP9-21 PF05486.7 CCF51812.1 - 1.2e-18 66.6 0.4 1.6e-18 66.1 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF1180 PF06679.7 CCF51812.1 - 0.7 9.7 4.0 0.99 9.2 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mito_carr PF00153.22 CCF51813.1 - 6.3e-66 218.1 5.5 5.5e-23 80.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMG_box PF00505.14 CCF51814.1 - 1.3e-24 86.2 0.4 1.8e-24 85.8 0.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF51814.1 - 2.6e-19 69.3 1.0 4.5e-19 68.5 0.7 1.4 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 CCF51814.1 - 0.022 15.0 0.6 0.025 14.8 0.3 1.3 1 1 0 1 1 1 0 YABBY protein CHDNT PF08073.7 CCF51814.1 - 0.037 13.6 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain PS_Dcarbxylase PF02666.10 CCF51815.1 - 9.2e-46 155.6 0.0 1.3e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Dehydratase_LU PF02286.10 CCF51815.1 - 0.048 11.8 0.0 0.081 11.1 0.0 1.3 1 0 0 1 1 1 0 Dehydratase large subunit AAA_12 PF13087.1 CCF51816.1 - 1.5e-58 197.4 0.0 2.5e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCF51816.1 - 2.2e-48 164.9 0.5 5.2e-48 163.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCF51816.1 - 1.5e-12 47.5 0.6 1e-08 35.0 0.0 3.1 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CCF51816.1 - 2.9e-11 42.9 1.3 5.9e-11 41.9 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 CCF51816.1 - 0.00097 18.5 0.1 0.0071 15.6 0.0 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 CCF51816.1 - 0.0022 18.0 0.8 0.77 9.7 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 CCF51816.1 - 0.0023 17.4 0.0 8.1 5.8 0.0 3.3 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CCF51816.1 - 0.0044 16.2 0.1 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein IATP PF04568.7 CCF51817.1 - 2e-17 63.0 1.1 2.2e-17 62.8 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP UPF0449 PF15136.1 CCF51817.1 - 0.0068 16.5 0.7 0.008 16.3 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 DUF1366 PF07104.6 CCF51817.1 - 0.012 15.2 3.5 0.016 14.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF2730 PF10805.3 CCF51817.1 - 0.029 14.0 1.0 0.039 13.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Atg14 PF10186.4 CCF51817.1 - 0.034 13.0 1.1 0.03 13.2 0.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MOFRL PF05161.8 CCF51817.1 - 0.038 14.1 0.3 0.047 13.8 0.2 1.4 1 1 0 1 1 1 0 MOFRL family YgaB PF14182.1 CCF51817.1 - 0.053 13.7 3.7 0.073 13.3 2.5 1.2 1 0 0 1 1 1 0 YgaB-like protein DUF4140 PF13600.1 CCF51817.1 - 0.074 13.5 2.3 0.12 12.8 1.6 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) NinG PF05766.7 CCF51817.1 - 0.085 12.6 3.8 0.11 12.2 2.7 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein TMPIT PF07851.8 CCF51817.1 - 0.17 10.9 0.9 0.2 10.7 0.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 CCF51817.1 - 0.34 10.4 3.2 0.38 10.3 2.2 1.1 1 0 0 1 1 1 0 IncA protein PspB PF06667.7 CCF51817.1 - 1.2 9.1 3.8 1.6 8.6 2.6 1.2 1 0 0 1 1 1 0 Phage shock protein B Bap31 PF05529.7 CCF51817.1 - 1.6 8.1 5.8 1.9 7.9 4.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like ATP_sub_h PF10775.4 CCF51818.1 - 5.1e-24 83.7 1.5 7.5e-24 83.2 1.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 CCF51818.1 - 0.041 13.7 0.1 0.065 13.1 0.0 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 eIF2_C PF09173.6 CCF51819.1 - 4.5e-38 129.1 0.1 1.1e-37 127.8 0.1 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 CCF51819.1 - 2.8e-37 127.9 0.0 4.8e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CCF51819.1 - 2.7e-13 49.8 2.1 3.7e-13 49.3 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF51819.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCF51819.1 - 0.06 13.1 0.0 0.25 11.1 0.0 2.0 2 1 0 3 3 3 0 Dynamin family muHD PF10291.4 CCF51820.1 - 1.6e-60 204.5 0.0 2.3e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CCF51820.1 - 3.5e-10 39.9 2.3 4.4e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SGT1 PF07093.6 CCF51820.1 - 0.0053 15.2 3.3 0.0079 14.6 2.3 1.2 1 0 0 1 1 1 1 SGT1 protein Exonuc_VII_L PF02601.10 CCF51820.1 - 0.019 14.1 6.1 0.041 13.0 4.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2335 PF10097.4 CCF51820.1 - 0.023 14.3 0.9 6.2 6.5 0.0 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Pkinase PF00069.20 CCF51821.1 - 6.7e-73 245.0 0.0 8.2e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51821.1 - 6.6e-32 110.6 0.0 8.4e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCF51821.1 - 0.00014 20.9 0.0 0.0005 19.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCF51821.1 - 0.00048 19.9 0.0 0.00098 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCF51821.1 - 0.002 17.1 0.0 0.015 14.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CCF51821.1 - 0.017 14.4 0.0 0.058 12.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_35 PF01301.14 CCF51822.1 - 3.7e-72 243.3 0.0 5.6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 CCF51822.1 - 1.1e-43 147.9 2.8 8.1e-21 74.3 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 CCF51822.1 - 7.6e-10 38.4 4.8 9.1e-09 34.9 0.5 2.5 2 0 0 2 2 2 2 Beta-galactosidase, domain 2 Glyco_hydro_2_N PF02837.13 CCF51822.1 - 1e-05 25.1 0.3 0.024 14.2 0.0 2.8 2 0 0 2 2 2 2 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom3 PF13363.1 CCF51822.1 - 4.2e-05 22.8 0.0 9.6e-05 21.6 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 CCF51822.1 - 0.0013 18.0 0.0 0.0032 16.7 0.0 1.7 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BiPBP_C PF06832.7 CCF51822.1 - 0.036 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family LYTB PF02401.13 CCF51822.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.5 2 0 0 2 2 2 0 LytB protein LSM PF01423.17 CCF51823.1 - 2.3e-18 65.4 0.3 3e-18 65.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain DNA_repr_REX1B PF14966.1 CCF51824.1 - 2.2e-07 31.1 1.6 0.017 15.4 0.2 2.7 3 0 0 3 3 3 2 DNA repair REX1-B DUF4618 PF15397.1 CCF51824.1 - 0.0033 16.8 2.3 0.0048 16.2 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) TSC22 PF01166.13 CCF51824.1 - 0.014 15.3 6.2 0.76 9.7 0.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family LEH PF07858.7 CCF51824.1 - 0.025 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain COMP PF11598.3 CCF51824.1 - 1.1 9.3 4.6 4.3 7.5 0.3 2.6 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Lge1 PF11488.3 CCF51824.1 - 2.5 8.3 6.0 7 6.9 3.4 2.4 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Ribosomal_S4 PF00163.14 CCF51825.1 - 2e-28 98.5 1.5 3.3e-28 97.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCF51825.1 - 2.2e-11 42.9 1.4 2.2e-11 42.9 0.9 3.1 4 0 0 4 4 4 1 S4 domain Ribosomal_L21e PF01157.13 CCF51826.1 - 5.5e-37 125.5 3.0 7e-37 125.2 1.6 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e DUF3708 PF12501.3 CCF51826.1 - 0.067 13.0 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Mito_carr PF00153.22 CCF51827.1 - 3.6e-76 250.9 5.3 1.1e-25 89.1 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.19 CCF51828.1 - 7.3e-152 506.3 2.6 8.3e-152 506.1 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Got1 PF04178.7 CCF51829.1 - 7.1e-29 100.3 11.0 9.6e-29 99.8 7.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4396 PF14342.1 CCF51829.1 - 0.26 11.4 2.8 0.37 10.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) ABC2_membrane_3 PF12698.2 CCF51829.1 - 4.5 6.2 10.1 6.2 5.7 7.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-primase PF09329.6 CCF51830.1 - 2e-14 52.8 2.0 4.7e-14 51.7 1.4 1.7 1 0 0 1 1 1 1 Primase zinc finger Rhabdo_ncap PF00945.13 CCF51830.1 - 0.28 9.7 0.7 0.48 8.9 0.5 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RNase_P_p30 PF01876.11 CCF51832.1 - 3e-50 169.3 0.0 4.3e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 adh_short PF00106.20 CCF51833.1 - 1.2e-22 80.6 0.2 1.7e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF51833.1 - 7.6e-09 35.4 0.2 1.7e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF51833.1 - 2.2e-07 30.9 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCF51833.1 - 0.0025 17.8 0.1 0.018 15.0 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCF51833.1 - 0.046 12.4 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_3 PF07859.8 CCF51835.1 - 5.2e-34 117.6 0.0 6.4e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF51835.1 - 2.9e-08 33.5 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF51835.1 - 8.9e-08 31.6 0.0 3.8e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCF51835.1 - 0.00016 21.6 1.2 0.00033 20.6 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCF51835.1 - 0.001 17.6 0.0 0.0016 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 CCF51835.1 - 0.0051 16.1 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 CCF51835.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CCF51835.1 - 0.019 14.7 0.0 0.047 13.3 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 CCF51835.1 - 0.038 13.5 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 CCF51835.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase_phd PF10503.4 CCF51835.1 - 0.056 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase MIP PF00230.15 CCF51836.1 - 3.5e-45 154.2 4.2 4.7e-45 153.8 2.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein Collagen PF01391.13 CCF51836.1 - 0.0022 17.4 9.0 0.0073 15.8 6.3 1.9 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HSP90 PF00183.13 CCF51837.1 - 1.8e-248 825.3 31.0 2.1e-248 825.0 21.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CCF51837.1 - 6.3e-12 45.1 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCF51837.1 - 1.2e-11 44.4 0.3 1.2e-11 44.4 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tom37_C PF11801.3 CCF51837.1 - 0.28 11.0 11.3 0.43 10.4 4.2 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain Peptidase_C37 PF05416.7 CCF51837.1 - 1.5 7.0 9.2 0.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF1510 PF07423.6 CCF51837.1 - 6.5 6.0 21.3 0.23 10.8 8.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Exo_endo_phos PF03372.18 CCF51838.1 - 1.5e-22 80.7 0.1 2.8e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCF51838.1 - 2.9e-15 55.4 7.8 2.9e-07 29.9 0.6 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF51838.1 - 2.9e-11 42.9 15.3 9e-08 31.7 2.5 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CCF51838.1 - 3.1e-06 26.4 6.2 0.7 10.1 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CCF51838.1 - 0.0014 18.5 7.1 3.5 8.2 0.0 4.4 4 0 0 4 4 4 2 Leucine rich repeat Pkinase PF00069.20 CCF51839.1 - 2.2e-59 200.7 0.0 9.9e-58 195.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51839.1 - 8.5e-28 97.1 0.0 1.1e-26 93.4 0.0 2.2 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF51839.1 - 3.1e-05 23.0 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCF51839.1 - 0.015 15.0 0.7 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family SMC_N PF02463.14 CCF51841.1 - 1.1e-72 243.8 9.4 2.2e-71 239.5 6.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCF51841.1 - 6.3e-26 90.6 0.1 3.7e-25 88.2 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCF51841.1 - 1.3e-12 48.2 7.8 1.4e-06 28.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 CCF51841.1 - 3.6e-12 47.0 2.2 3.6e-12 47.0 1.5 7.4 3 2 3 6 6 6 1 AAA domain AAA_29 PF13555.1 CCF51841.1 - 0.00095 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CCF51841.1 - 0.005 16.0 29.8 0.02 14.1 2.7 4.9 2 2 2 4 4 4 4 Reovirus sigma C capsid protein Cupin_7 PF12973.2 CCF51842.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 ChrR Cupin-like domain Peroxin-13_N PF04088.8 CCF51844.1 - 7.9e-53 178.6 0.1 1.6e-52 177.6 0.1 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CCF51844.1 - 3.6e-12 45.4 0.0 7.3e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF51844.1 - 3.8e-12 45.5 0.0 6.5e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF51844.1 - 2.3e-11 43.0 0.0 4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 CCF51844.1 - 0.023 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CCF51845.1 - 7.3e-09 35.3 4.3 1.2e-08 34.6 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCF51845.1 - 4.6e-07 29.4 4.1 7.1e-07 28.7 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF51845.1 - 2.3e-06 27.1 3.9 3.8e-06 26.5 2.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCF51845.1 - 3e-05 23.9 4.4 4.9e-05 23.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF51845.1 - 0.0013 18.4 0.8 0.0037 16.9 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCF51845.1 - 0.0063 16.1 2.6 0.011 15.4 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF51845.1 - 0.018 15.1 2.2 0.035 14.2 1.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger MscS_TM PF12794.2 CCF51845.1 - 0.74 8.3 6.1 1.3 7.5 4.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DAHP_synth_1 PF00793.15 CCF51846.1 - 6e-92 307.1 0.0 7.6e-92 306.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SRX PF09201.5 CCF51846.1 - 0.0011 18.6 0.0 0.0032 17.1 0.0 1.7 1 1 0 1 1 1 1 SRX CBFD_NFYB_HMF PF00808.18 CCF51847.1 - 1.1e-17 63.7 0.1 2.3e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF51847.1 - 0.0055 16.7 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ECH PF00378.15 CCF51848.1 - 3.4e-44 150.8 0.0 4.5e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2138 PF09909.4 CCF51848.1 - 0.029 12.5 0.0 0.039 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Kinesin PF00225.18 CCF51849.1 - 2.3e-99 332.2 0.0 1.2e-53 181.9 0.0 3.1 2 0 0 2 2 2 2 Kinesin motor domain TMF_DNA_bd PF12329.3 CCF51849.1 - 0.0012 18.5 5.4 0.0012 18.5 3.8 14.5 13 3 2 15 15 15 3 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CCF51849.1 - 0.0018 18.1 26.4 0.0018 18.1 18.3 10.3 4 2 3 8 8 8 3 Autophagy protein 16 (ATG16) Img2 PF05046.9 CCF51849.1 - 3.1 8.0 5.7 22 5.3 0.0 4.4 4 1 2 6 6 6 0 Mitochondrial large subunit ribosomal protein (Img2) SH3_1 PF00018.23 CCF51850.1 - 5.5e-12 44.8 0.1 1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF51850.1 - 3.1e-09 36.2 0.0 5.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF51850.1 - 6.8e-09 35.0 0.0 1.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCF51850.1 - 0.029 14.5 0.1 0.062 13.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain L51_S25_CI-B8 PF05047.11 CCF51851.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3990 PF13151.1 CCF51852.1 - 0.042 13.2 0.1 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Lysine_decarbox PF03641.9 CCF51855.1 - 1.9e-31 108.5 0.1 3.9e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase ABC_tran PF00005.22 CCF51855.1 - 2.4e-14 53.8 0.0 1e-13 51.7 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCF51855.1 - 2.3e-08 34.3 0.6 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCF51855.1 - 1.9e-06 27.1 0.0 0.0043 16.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CCF51855.1 - 0.00065 19.1 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCF51855.1 - 0.0013 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCF51855.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.14 CCF51855.1 - 0.02 14.1 0.1 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 CCF51855.1 - 0.029 13.8 0.0 0.49 9.8 0.0 2.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CCF51855.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCF51855.1 - 0.049 14.4 0.4 0.1 13.4 0.3 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCF51855.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CCF51855.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 CCF51855.1 - 0.11 12.0 0.1 8.6 5.8 0.1 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 CCF51855.1 - 0.11 11.3 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 CCF51855.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CCF51855.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CCF51855.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein UAA PF08449.6 CCF51856.1 - 5.7e-71 238.9 5.9 1.5e-64 217.7 2.8 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 CCF51856.1 - 1.7e-13 50.6 21.4 2.2e-10 40.6 3.1 4.2 5 0 0 5 5 5 2 EamA-like transporter family TPT PF03151.11 CCF51856.1 - 1.9e-09 37.3 15.7 1.5e-06 27.9 4.6 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CCF51856.1 - 8.9e-06 25.8 2.1 8.9e-06 25.8 1.5 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CCF51856.1 - 1.4e-05 24.3 3.4 0.0084 15.2 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter UPF0546 PF10639.4 CCF51856.1 - 0.0032 17.2 5.5 0.045 13.5 0.2 2.5 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 Wzy_C PF04932.10 CCF51856.1 - 0.038 13.7 0.5 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 O-Antigen ligase TPR_12 PF13424.1 CCF51857.1 - 0.029 14.2 5.6 0.041 13.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF51857.1 - 0.058 13.2 0.6 0.31 10.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 CCF51858.1 - 5e-98 328.7 0.0 2e-97 326.7 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCF51858.1 - 5.3e-07 29.6 0.2 0.00033 20.5 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCF51858.1 - 1.1e-06 28.7 4.8 0.28 11.4 0.2 4.7 3 2 1 4 4 4 3 HEAT repeats Tim54 PF11711.3 CCF51859.1 - 9.7e-60 202.1 3.7 1.2e-59 201.8 0.0 2.8 1 1 1 2 2 2 1 Inner membrane protein import complex subunit Tim54 HNOBA PF07701.9 CCF51859.1 - 0.079 12.1 2.6 0.14 11.3 1.8 1.3 1 0 0 1 1 1 0 Heme NO binding associated Secretin_N_2 PF07655.8 CCF51859.1 - 7.1 7.0 27.9 0.11 12.9 12.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain PAP1 PF08601.5 CCF51859.1 - 8.2 5.9 18.4 0.0098 15.6 3.0 2.4 2 0 0 2 2 2 0 Transcription factor PAP1 RNase_PH PF01138.16 CCF51860.1 - 2.6e-26 92.4 0.1 4.3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 tRNA-synt_2b PF00587.20 CCF51861.1 - 4.6e-68 228.1 0.1 7.1e-68 227.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF51861.1 - 9.3e-21 73.5 0.2 5.3e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain FMN_red PF03358.10 CCF51862.1 - 1.7e-09 37.3 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CCF51862.1 - 2e-06 27.4 0.0 4.8e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 CCF51862.1 - 1.8e-05 24.7 0.5 5.4e-05 23.2 0.3 2.0 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 CCF51862.1 - 0.0017 17.7 0.1 0.0032 16.8 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin WD40 PF00400.27 CCF51863.1 - 5.5e-72 235.2 21.6 1e-12 47.3 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CCF51863.1 - 5e-11 41.4 13.9 0.00017 19.8 0.1 5.0 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCF51863.1 - 0.00019 20.3 4.2 4.5 5.8 0.2 4.6 1 1 3 4 4 4 4 Nup133 N terminal like LisH PF08513.6 CCF51863.1 - 0.029 14.1 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 LisH NUDIX PF00293.23 CCF51864.1 - 4.1e-16 58.8 0.0 2e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.21 CCF51866.1 - 1.2e-19 69.3 31.9 4.4e-05 23.5 0.5 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF51866.1 - 7.7e-19 66.9 24.9 2.1e-08 34.0 0.1 5.3 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCF51866.1 - 6.5e-09 35.5 28.6 0.014 15.6 0.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCF51866.1 - 0.0019 18.2 3.4 0.35 11.0 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding IGPD PF00475.13 CCF51866.1 - 0.0093 15.8 0.1 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase zf-C2H2_6 PF13912.1 CCF51866.1 - 1.5 8.8 13.8 0.8 9.6 0.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger IF-2B PF01008.12 CCF51867.1 - 6e-57 192.7 0.0 8.2e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DEAD PF00270.24 CCF51868.1 - 1.5e-47 161.2 0.0 2.8e-45 153.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF51868.1 - 3.7e-25 87.5 0.2 1e-24 86.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aminotran_3 PF00202.16 CCF51869.1 - 8.1e-109 363.5 0.0 1.1e-108 363.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCF51869.1 - 4.4e-05 22.6 0.0 6.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF51869.1 - 0.0022 17.1 0.0 0.0055 15.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2007 PF09413.5 CCF51869.1 - 0.004 16.9 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF2007) DUF3128 PF11326.3 CCF51870.1 - 2.3e-22 78.9 0.3 3.2e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) zf-H2C2_2 PF13465.1 CCF51871.1 - 5.4e-25 86.4 18.3 3.5e-07 30.2 0.1 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCF51871.1 - 7.3e-20 70.0 27.1 3.8e-06 26.9 1.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF51871.1 - 2.5e-11 43.0 23.3 0.0097 16.1 1.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCF51871.1 - 0.00047 20.2 7.0 0.27 11.4 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Daxx PF03344.10 CCF51871.1 - 0.00054 18.5 14.8 0.00054 18.5 10.3 2.2 2 0 0 2 2 2 1 Daxx Family zf-C2H2_6 PF13912.1 CCF51871.1 - 0.0031 17.3 14.8 0.026 14.4 0.7 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 CCF51871.1 - 0.011 15.8 9.8 0.4 10.9 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Nop14 PF04147.7 CCF51871.1 - 0.011 13.6 20.3 0.018 13.0 14.1 1.2 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 CCF51871.1 - 0.018 15.5 18.7 0.018 15.5 13.0 2.7 3 0 0 3 3 1 0 Protein of unknown function (FYDLN_acid) zf-TRAF PF02176.13 CCF51871.1 - 0.037 14.4 1.0 0.037 14.4 0.7 2.8 2 1 1 3 3 3 0 TRAF-type zinc finger NOA36 PF06524.7 CCF51871.1 - 0.085 12.1 16.3 0.16 11.2 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 CCF51871.1 - 0.15 10.0 16.3 0.23 9.4 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CCF51871.1 - 0.42 9.8 21.6 0.78 8.9 15.0 1.4 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.7 CCF51871.1 - 0.9 9.1 14.8 2.2 7.9 10.3 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2HC_2 PF13913.1 CCF51871.1 - 1.7 8.4 14.1 0.76 9.5 0.6 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type DUF1510 PF07423.6 CCF51871.1 - 2.1 7.6 15.4 6.1 6.1 10.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 CCF51871.1 - 9.5 4.8 14.0 15 4.2 9.7 1.2 1 0 0 1 1 1 0 Paf1 FGGY_C PF02782.11 CCF51872.1 - 0.034 13.7 0.1 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Sel1 PF08238.7 CCF51873.1 - 2.3e-09 37.5 18.8 2.7e-07 30.9 0.1 5.0 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.12 CCF51873.1 - 0.024 14.5 0.8 5.2 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_6 PF14259.1 CCF51874.1 - 4.2e-06 26.6 0.0 6.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF51874.1 - 0.0057 16.2 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fip1 PF05182.8 CCF51875.1 - 9e-21 72.8 1.9 1.8e-20 71.8 1.3 1.5 1 0 0 1 1 1 1 Fip1 motif PAS_9 PF13426.1 CCF51876.1 - 1.6e-24 86.2 0.0 2e-13 50.6 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.6 CCF51876.1 - 1.1e-14 54.2 0.0 4.9e-07 29.7 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 CCF51876.1 - 3.3e-14 52.6 0.0 3.5e-10 39.6 0.0 3.3 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.5 CCF51876.1 - 1.4e-07 31.5 0.0 0.00015 21.8 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 CCF51876.1 - 2.6e-06 27.0 0.0 0.0067 16.2 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 CCF51876.1 - 0.0021 18.0 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain Adap_comp_sub PF00928.16 CCF51877.1 - 2.9e-84 282.2 0.1 5.7e-84 281.3 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCF51877.1 - 0.0018 18.0 0.9 0.0033 17.1 0.6 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LSM PF01423.17 CCF51878.1 - 3.5e-16 58.5 0.5 4.5e-16 58.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 CCF51878.1 - 0.07 12.8 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) XPG_I PF00867.13 CCF51879.1 - 3.4e-24 84.7 0.1 7.2e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCF51879.1 - 5.2e-21 74.7 0.0 1.3e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 CCF51879.1 - 2.8e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 CCF51879.1 - 0.029 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 CCF51879.1 - 0.096 12.6 0.2 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.7 CCF51880.1 - 1.2e-25 90.0 0.0 7e-25 87.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 90 PXA PF02194.10 CCF51882.1 - 6.2e-36 123.6 0.0 6.2e-36 123.6 0.0 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 CCF51882.1 - 4e-29 100.9 0.0 1.4e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 CCF51882.1 - 3.2e-14 52.6 0.0 1.1e-13 51.0 0.0 2.0 1 0 0 1 1 1 1 PX domain RGS PF00615.14 CCF51882.1 - 2e-09 37.5 0.1 6.1e-09 36.0 0.1 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF342 PF03961.8 CCF51882.1 - 0.002 16.5 1.4 0.022 13.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF342) Lebercilin PF15619.1 CCF51882.1 - 0.47 9.8 9.6 0.3 10.4 0.5 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.6 CCF51882.1 - 2.7 8.4 6.5 9.8 6.6 0.3 3.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal YlqD PF11068.3 CCF51882.1 - 3.2 7.8 8.1 1.1 9.2 3.3 1.9 2 0 0 2 2 2 0 YlqD protein Mog1 PF04603.7 CCF51884.1 - 8.8e-27 93.7 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Dicty_REP PF05086.7 CCF51884.1 - 0.19 9.4 0.8 0.19 9.4 0.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sterol_MT_C PF08498.5 CCF51885.1 - 5.4e-29 99.9 0.5 8.2e-29 99.3 0.4 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CCF51885.1 - 5.7e-19 68.2 0.0 7.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF51885.1 - 7.8e-19 67.9 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCF51885.1 - 6.6e-16 58.2 0.0 8.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCF51885.1 - 1.4e-15 57.4 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF51885.1 - 1.7e-13 50.8 0.0 3.5e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF51885.1 - 2.4e-13 50.6 0.0 9e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF51885.1 - 4.4e-12 46.2 0.0 8.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF51885.1 - 4e-11 42.9 0.0 1.4e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF51885.1 - 2.9e-08 33.1 0.0 4.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 CCF51885.1 - 4.6e-05 22.5 0.0 9.2e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 CCF51885.1 - 6.8e-05 22.3 0.0 0.00014 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CCF51885.1 - 0.00022 20.8 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 CCF51885.1 - 0.00073 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CCF51885.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 CCF51885.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 CCF51885.1 - 0.0041 17.9 0.1 0.043 14.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCF51885.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CCF51885.1 - 0.031 13.3 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 CCF51885.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DHFR_1 PF00186.14 CCF51886.1 - 1.2e-31 109.4 0.0 4e-31 107.7 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase RVT_2 PF07727.9 CCF51887.1 - 5.2e-13 48.5 0.1 6.5e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF51887.1 - 0.17 11.1 0.7 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ERCC4 PF02732.10 CCF51888.1 - 5.3e-27 94.3 0.0 1.7e-25 89.4 0.0 2.6 2 0 0 2 2 2 1 ERCC4 domain ATP-synt_ab PF00006.20 CCF51889.1 - 2.3e-62 210.2 0.0 3.7e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CCF51889.1 - 1.2e-23 83.0 3.0 1.2e-23 83.0 2.1 2.1 3 0 0 3 3 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 CCF51889.1 - 1.2e-23 83.6 0.1 2.3e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 CCF51889.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 CCF51889.1 - 0.0091 15.4 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCF51889.1 - 0.019 14.1 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CCF51889.1 - 0.022 13.6 0.8 0.095 11.5 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 CCF51889.1 - 0.024 13.7 0.2 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 CCF51889.1 - 0.025 14.5 1.6 0.091 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 CCF51889.1 - 0.031 14.0 0.3 0.98 9.1 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CCF51889.1 - 0.036 14.2 0.0 0.26 11.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF51889.1 - 0.043 13.9 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCF51889.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 CCF51889.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCF51889.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF4451 PF14616.1 CCF51890.1 - 0.25 11.1 0.0 0.25 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Cyclin_N PF00134.18 CCF51891.1 - 1.6e-08 34.1 0.5 8.8e-08 31.7 0.3 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain DnaJ PF00226.26 CCF51892.1 - 7.9e-16 57.5 0.7 2.3e-15 56.0 0.0 2.1 3 0 0 3 3 3 1 DnaJ domain DUF2450 PF10475.4 CCF51892.1 - 0.038 12.9 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Cyclin_N PF00134.18 CCF51893.1 - 6.8e-12 45.0 0.1 1.8e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCF51893.1 - 0.00026 20.8 0.3 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 CCF51893.1 - 0.0012 18.5 0.1 0.0043 16.8 0.0 2.0 1 1 0 1 1 1 1 Transcription factor TFIIB repeat TPT PF03151.11 CCF51894.1 - 3.9e-24 85.0 12.8 3.9e-24 85.0 8.8 2.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family GSAP-16 PF14959.1 CCF51894.1 - 0.047 13.4 1.2 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term Sec61_beta PF03911.11 CCF51894.1 - 0.2 11.4 3.9 16 5.4 0.2 3.6 3 0 0 3 3 3 0 Sec61beta family DUF1118 PF06549.7 CCF51894.1 - 1.7 8.7 7.2 0.55 10.3 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) Helicase_C_2 PF13307.1 CCF51895.1 - 2.1e-53 180.7 0.0 6.5e-53 179.1 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CCF51895.1 - 1.6e-45 154.6 0.0 3e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 2-oxoacid_dh PF00198.18 CCF51896.1 - 3.4e-63 213.0 0.0 5.5e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCF51896.1 - 1.9e-18 65.8 0.1 3.8e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCF51896.1 - 2e-15 56.1 0.3 5.4e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCF51896.1 - 0.012 15.3 0.0 0.095 12.3 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like SIS PF01380.17 CCF51897.1 - 5e-59 197.5 0.1 1.1e-32 112.3 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCF51897.1 - 9e-28 97.0 0.0 2.5e-18 65.9 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCF51897.1 - 9.1e-18 64.4 0.0 2.1e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCF51897.1 - 1.8e-12 47.0 0.0 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCF51897.1 - 1.1e-07 30.8 0.0 1.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CCF51897.1 - 0.024 14.3 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 SIS domain BRCA-2_OB1 PF09103.5 CCF51898.1 - 2e-33 114.5 0.0 3.4e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 CCF51898.1 - 9.7e-06 25.2 0.5 2.5e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.13 CCF51898.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat DAP PF15228.1 CCF51899.1 - 0.11 13.2 5.1 0.2 12.4 3.6 1.4 1 0 0 1 1 1 0 Death-associated protein FAM176 PF14851.1 CCF51899.1 - 0.11 12.1 0.3 0.59 9.7 0.2 1.9 2 0 0 2 2 2 0 FAM176 family TAF4 PF05236.9 CCF51899.1 - 1 8.6 6.4 1.4 8.0 4.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SR-25 PF10500.4 CCF51899.1 - 1.6 8.1 10.3 2.5 7.4 7.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.8 CCF51899.1 - 2.3 8.6 7.3 36 4.8 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RVT_2 PF07727.9 CCF51902.1 - 7.4e-50 169.2 1.0 1.2e-49 168.5 0.7 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chitin_synth_2 PF03142.10 CCF51903.1 - 7.3e-241 800.1 0.2 9.8e-241 799.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 CCF51903.1 - 6.8e-149 497.0 0.0 9.4e-149 496.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 CCF51903.1 - 3.2e-16 58.8 0.0 1.4e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 CCF51903.1 - 2.4e-15 56.7 2.1 2.4e-15 56.7 1.5 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 CCF51903.1 - 1.5e-14 53.4 6.2 1.9e-14 53.1 1.9 2.9 3 0 0 3 3 3 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 CCF51903.1 - 2.5e-14 53.6 0.0 3.6e-12 46.5 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCF51903.1 - 0.004 16.8 0.0 0.42 10.2 0.0 2.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCF51903.1 - 0.019 14.2 0.1 0.39 9.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 TFIIF_alpha PF05793.7 CCF51904.1 - 4.2e-07 28.7 43.4 0.00014 20.4 24.3 3.3 3 1 0 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mre11_DNA_bind PF04152.9 CCF51904.1 - 0.63 9.8 4.1 14 5.5 0.3 2.7 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Thymidylate_kin PF02223.12 CCF51906.1 - 5.6e-45 153.0 0.0 1.1e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 CCF51906.1 - 0.0026 17.7 0.3 0.009 15.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain gag_pre-integrs PF13976.1 CCF51908.1 - 0.00018 21.0 3.0 0.0003 20.3 1.7 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF51908.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CBM_25 PF03423.8 CCF51908.1 - 0.22 11.6 1.3 0.6 10.2 0.3 2.1 2 1 1 3 3 3 0 Carbohydrate binding domain (family 25) Mpv17_PMP22 PF04117.7 CCF51910.1 - 2.8e-24 84.5 3.9 5.9e-24 83.4 2.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PWI PF01480.12 CCF51911.1 - 2.7e-08 33.7 0.2 2.7e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 CCF51911.1 - 1e-06 28.2 0.0 3.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51911.1 - 0.072 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sec23_trunk PF04811.10 CCF51912.1 - 5.3e-74 248.6 0.0 9.2e-74 247.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCF51912.1 - 3.8e-23 80.8 0.4 8.4e-23 79.7 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCF51912.1 - 3.6e-16 58.4 8.9 6.8e-16 57.5 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCF51912.1 - 5e-16 58.9 0.0 1.4e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCF51912.1 - 2.1e-07 30.5 0.0 4.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 CCF51912.1 - 2.7e-06 27.1 0.8 5.7e-06 26.0 0.6 1.6 1 0 0 1 1 1 1 WW domain rve PF00665.21 CCF51916.1 - 4.6e-07 29.9 0.0 8.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CCF51916.1 - 0.0081 15.8 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_3 PF13358.1 CCF51916.1 - 0.047 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease RVT_2 PF07727.9 CCF51917.1 - 9e-55 185.3 0.2 1.1e-54 185.0 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CKS PF01111.14 CCF51918.1 - 5.9e-34 115.7 0.6 9.8e-34 115.0 0.4 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Tim54 PF11711.3 CCF51918.1 - 0.031 12.8 12.8 0.043 12.4 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TT_ORF1 PF02956.9 CCF51918.1 - 0.061 11.7 4.3 0.059 11.8 3.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 Ycf1 PF05758.7 CCF51918.1 - 0.68 7.5 12.5 0.64 7.6 8.7 1.1 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CCF51918.1 - 1 9.2 5.9 1.2 9.0 4.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF913 PF06025.7 CCF51918.1 - 2 7.1 9.6 2.7 6.6 6.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BTV_NS2 PF04514.7 CCF51918.1 - 2.9 6.6 17.6 3.9 6.2 12.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SAPS PF04499.10 CCF51918.1 - 3.2 6.2 15.8 4.3 5.8 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.1 CCF51918.1 - 6.8 5.5 6.7 11 4.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AhpC-TSA PF00578.16 CCF51919.1 - 2.2e-25 88.7 0.0 3.5e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCF51919.1 - 8.3e-14 51.3 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CCF51919.1 - 0.008 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DPBB_1 PF03330.13 CCF51920.1 - 3e-10 39.9 0.1 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Porin_4 PF13609.1 CCF51920.1 - 0.055 12.9 0.9 0.066 12.7 0.6 1.2 1 0 0 1 1 1 0 Gram-negative porin Barwin PF00967.12 CCF51920.1 - 0.1 12.2 0.6 0.2 11.3 0.1 1.5 1 1 0 1 1 1 0 Barwin family DUF2796 PF10986.3 CCF51922.1 - 0.00012 22.1 1.6 0.00012 22.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) PBP1_TM PF14812.1 CCF51922.1 - 0.0056 16.9 5.7 0.008 16.4 3.9 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal LAT PF15234.1 CCF51922.1 - 0.047 13.1 1.2 0.062 12.7 0.8 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Nucleoplasmin PF03066.10 CCF51922.1 - 0.12 11.8 2.0 0.16 11.4 1.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3537 PF12056.3 CCF51922.1 - 0.15 10.7 0.1 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FAM176 PF14851.1 CCF51922.1 - 0.17 11.5 0.5 0.24 11.0 0.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 CCF51922.1 - 1 8.0 7.8 1.3 7.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sel1 PF08238.7 CCF51923.1 - 3.8e-36 122.7 33.7 6.1e-06 26.7 0.9 8.0 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.1 CCF51923.1 - 5 7.8 9.8 4.1 8.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat LSM PF01423.17 CCF51924.1 - 7.5e-10 38.2 0.1 9.7e-10 37.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2226 PF09987.4 CCF51924.1 - 0.047 12.8 0.0 0.056 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) DHO_dh PF01180.16 CCF51925.1 - 6.9e-99 330.5 0.0 9.8e-99 330.0 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCF51925.1 - 2.5e-05 23.2 0.2 0.0046 15.8 0.2 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase FAT PF02259.18 CCF51926.1 - 1.8e-123 412.0 3.0 1.8e-123 412.0 2.1 2.0 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 CCF51926.1 - 3.9e-59 199.1 0.5 5e-58 195.5 0.0 3.2 3 1 0 3 3 2 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CCF51926.1 - 1.3e-55 188.4 0.1 2.4e-55 187.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CCF51926.1 - 2.6e-40 136.5 0.2 2.6e-40 136.5 0.1 3.1 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 CCF51926.1 - 1.3e-20 73.4 13.7 0.00097 19.3 0.0 11.6 7 2 5 12 12 12 5 HEAT repeats FATC PF02260.15 CCF51926.1 - 6.6e-12 44.6 0.1 1.6e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CCF51926.1 - 2.3e-09 36.5 14.4 0.51 10.5 0.1 11.0 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.1 CCF51926.1 - 5.2e-05 23.5 22.5 1.1 9.8 0.3 11.7 11 2 2 13 13 11 2 HEAT-like repeat TPR_19 PF14559.1 CCF51926.1 - 0.0063 16.8 0.7 23 5.4 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat VHS PF00790.14 CCF51926.1 - 0.017 14.7 0.0 2.6 7.6 0.0 3.6 3 0 0 3 3 3 0 VHS domain TPR_1 PF00515.23 CCF51926.1 - 0.024 14.2 0.2 18 5.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF51926.1 - 0.039 13.7 0.6 42 4.2 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Cnd1 PF12717.2 CCF51926.1 - 0.056 13.2 2.9 2.1 8.1 0.0 4.4 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 TPR_11 PF13414.1 CCF51926.1 - 0.31 10.6 11.6 8.3 6.1 0.1 5.8 7 0 0 7 7 6 0 TPR repeat Adaptin_N PF01602.15 CCF51926.1 - 0.43 8.8 7.3 3.4 5.8 0.2 3.7 2 1 1 3 3 3 0 Adaptin N terminal region TPR_2 PF07719.12 CCF51926.1 - 2 8.5 9.4 4.1 7.5 0.2 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat Septin PF00735.13 CCF51927.1 - 1.1e-112 375.7 1.3 1.3e-112 375.3 0.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCF51927.1 - 1.6e-08 34.4 0.1 1.1e-07 31.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCF51927.1 - 2.6e-06 26.7 0.0 5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCF51927.1 - 1.3e-05 25.1 0.3 0.037 13.8 0.1 2.7 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CCF51927.1 - 2.5e-05 23.4 0.0 2.5e-05 23.4 0.0 2.4 3 0 0 3 3 3 1 AIG1 family FtsK_SpoIIIE PF01580.13 CCF51927.1 - 6.3e-05 22.5 0.1 0.00018 21.0 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 CCF51927.1 - 0.00015 21.2 0.2 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CCF51927.1 - 0.00082 18.8 0.1 0.001 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 CCF51927.1 - 0.0014 17.5 0.1 0.0029 16.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 CCF51927.1 - 0.0034 18.1 0.5 3 8.6 0.0 2.4 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCF51927.1 - 0.0039 17.4 2.1 0.0042 17.3 0.0 2.1 2 2 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 CCF51927.1 - 0.0068 16.7 0.6 0.029 14.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain IIGP PF05049.8 CCF51927.1 - 0.008 15.0 0.3 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CCF51927.1 - 0.0091 16.4 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CCF51927.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCF51927.1 - 0.015 14.8 0.2 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 CCF51927.1 - 0.015 14.4 0.1 0.062 12.4 0.1 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CCF51927.1 - 0.024 14.7 0.0 0.061 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCF51927.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CCF51927.1 - 0.027 13.3 0.4 0.056 12.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 CCF51927.1 - 0.047 13.3 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCF51927.1 - 0.052 13.4 1.5 0.54 10.1 0.0 2.7 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.12 CCF51927.1 - 0.091 12.5 1.7 0.66 9.7 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF87 SCAMP PF04144.8 CCF51928.1 - 5.2e-50 169.7 3.1 6.2e-50 169.5 2.1 1.1 1 0 0 1 1 1 1 SCAMP family DUF1700 PF08006.6 CCF51928.1 - 0.41 9.9 3.0 0.75 9.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Bacteriocin_IId PF09221.5 CCF51928.1 - 0.85 9.5 6.0 0.1 12.5 1.0 1.8 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Bromodomain PF00439.20 CCF51929.1 - 3.6e-39 132.5 1.9 2.2e-19 69.1 0.2 3.2 2 1 1 3 3 3 2 Bromodomain Ctr PF04145.10 CCF51930.1 - 9e-32 110.1 0.3 1.1e-31 109.7 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family ECH PF00378.15 CCF51931.1 - 2.4e-23 82.5 0.3 3.2e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DAO PF01266.19 CCF51932.1 - 1.1e-44 152.8 1.0 1.3e-44 152.5 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCF51932.1 - 0.00033 20.4 0.1 0.098 12.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCF51932.1 - 0.00061 19.9 0.0 0.84 9.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF51932.1 - 0.064 13.1 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4148 PF13663.1 CCF51932.1 - 0.075 12.8 0.0 19 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) NAD_binding_8 PF13450.1 CCF51932.1 - 0.079 13.0 0.3 0.22 11.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCF51932.1 - 1.2 7.8 7.0 7.1 5.3 4.9 2.1 1 1 0 1 1 1 0 FAD binding domain E1-E2_ATPase PF00122.15 CCF51933.1 - 4.7e-16 58.5 0.1 1.1e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCF51933.1 - 6.2e-15 55.8 0.0 1.1e-13 51.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF51933.1 - 6.8e-13 49.5 3.3 5.8e-10 39.9 2.3 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF51933.1 - 6.2e-12 45.3 0.0 2.2e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF51933.1 - 0.00039 20.0 0.2 0.0057 16.2 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.17 CCF51934.1 - 8.7e-19 66.9 0.0 1.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF51934.1 - 1.5e-14 53.7 0.0 2.1e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF51934.1 - 4.6e-09 35.9 0.0 6.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 CCF51935.1 - 4.6e-38 130.6 0.0 5.4e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 CCF51936.1 - 1.7e-68 230.6 0.0 2.3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF51936.1 - 1.8e-41 141.9 0.0 2.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CCF51936.1 - 1.5e-29 101.7 0.0 1.8e-14 53.4 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCF51936.1 - 2.6e-07 29.8 0.0 1.5e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 CCF51936.1 - 0.011 15.2 0.0 0.48 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) APH PF01636.18 CCF51936.1 - 0.068 12.8 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.26 CCF51937.1 - 9.7e-14 51.3 0.1 4.2e-11 42.8 0.0 3.3 3 0 0 3 3 3 1 BTB/POZ domain CAP_GLY PF01302.20 CCF51937.1 - 2.2e-07 30.4 0.0 4.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ribophorin_II PF05817.9 CCF51938.1 - 2.2e-07 29.5 0.2 2.6e-06 25.9 0.1 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II Ribosomal_S10 PF00338.17 CCF51941.1 - 1.7e-32 111.1 0.4 2e-32 110.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Dor1 PF04124.7 CCF51942.1 - 2.1e-20 72.4 6.4 1.9e-18 66.0 2.2 3.3 2 2 0 2 2 2 2 Dor1-like family TPP_enzyme_N PF02776.13 CCF51943.1 - 2.2e-54 183.5 0.0 6.5e-54 181.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCF51943.1 - 1.4e-48 164.3 0.1 5.4e-47 159.1 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCF51943.1 - 8.2e-38 129.2 0.4 4.6e-37 126.8 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 CCF51943.1 - 0.049 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GRAB PF10375.4 CCF51944.1 - 2.1e-07 30.2 1.1 2.1e-07 30.2 0.8 2.4 2 0 0 2 2 2 1 GRIP-related Arf-binding domain TPR_MLP1_2 PF07926.7 CCF51944.1 - 0.019 14.7 2.1 0.019 14.7 1.4 3.9 2 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein Filament PF00038.16 CCF51944.1 - 0.023 14.1 23.0 0.24 10.8 3.2 2.7 1 1 1 2 2 2 0 Intermediate filament protein SNARE PF05739.14 CCF51944.1 - 0.039 13.6 1.0 0.51 10.0 0.1 2.9 2 1 1 3 3 3 0 SNARE domain V_ATPase_I PF01496.14 CCF51944.1 - 0.04 11.7 13.2 0.14 9.9 2.5 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family LPP PF04728.8 CCF51944.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF3053 PF11254.3 CCF51944.1 - 0.087 12.0 1.9 0.089 12.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) bZIP_1 PF00170.16 CCF51944.1 - 0.089 12.7 0.1 0.089 12.7 0.0 4.3 3 2 2 5 5 5 0 bZIP transcription factor Reo_sigmaC PF04582.7 CCF51944.1 - 0.1 11.7 6.9 0.87 8.7 0.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CCF51944.1 - 0.11 12.3 8.6 0.27 11.0 0.6 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 CCF51944.1 - 0.12 12.2 29.2 0.083 12.7 6.0 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Allexi_40kDa PF05549.6 CCF51944.1 - 0.29 10.3 7.1 0.044 13.0 0.6 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein TBPIP PF07106.8 CCF51944.1 - 0.65 9.5 17.5 0.23 11.0 1.9 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF904 PF06005.7 CCF51944.1 - 0.99 9.7 19.0 6.5 7.1 0.0 4.6 2 1 0 2 2 1 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 CCF51944.1 - 1 9.1 5.3 1.3 8.8 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 CCF51944.1 - 1.1 8.8 11.6 0.49 10.0 1.1 3.0 2 2 0 2 2 2 0 Nucleoporin complex subunit 54 Rab5-bind PF09311.6 CCF51944.1 - 1.3 8.8 30.1 0.051 13.4 11.2 2.5 1 1 1 2 2 1 0 Rabaptin-like protein Spc42p PF11544.3 CCF51944.1 - 1.3 8.9 5.0 0.75 9.7 0.1 2.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p BLOC1_2 PF10046.4 CCF51944.1 - 2.7 8.2 6.4 1.7 8.8 0.4 2.6 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tho2 PF11262.3 CCF51944.1 - 3 6.8 4.7 1.7 7.5 0.6 2.0 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF812 PF05667.6 CCF51944.1 - 3.5 6.0 22.9 3.7 5.9 7.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Lectin_N PF03954.9 CCF51944.1 - 4.8 6.5 8.2 1.6 8.1 1.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain UPF0184 PF03670.8 CCF51944.1 - 9 6.5 11.2 13 6.0 0.1 3.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) Tup_N PF08581.5 CCF51944.1 - 9.3 6.5 11.3 0.82 9.9 0.6 3.6 3 1 1 4 4 4 0 Tup N-terminal KH_1 PF00013.24 CCF51945.1 - 3.5e-05 23.3 1.3 5.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CCF51945.1 - 6.5e-05 22.4 0.0 0.00019 20.9 0.0 1.8 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 CCF51945.1 - 0.069 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 KH domain Toxin_41 PF15521.1 CCF51946.1 - 0.11 11.6 0.1 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 41 DUF2514 PF10721.4 CCF51946.1 - 0.19 11.3 2.5 0.48 10.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) SMC_N PF02463.14 CCF51947.1 - 2e-59 200.5 15.4 7.7e-58 195.3 10.7 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCF51947.1 - 7.8e-29 100.0 0.1 2.5e-28 98.4 0.1 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCF51947.1 - 3.9e-14 53.3 0.9 9.3e-09 35.6 0.4 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCF51947.1 - 1.2e-08 34.3 0.0 2.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2968 PF11180.3 CCF51947.1 - 0.00028 20.3 2.7 0.00028 20.3 1.9 7.3 5 3 3 8 8 8 2 Protein of unknown function (DUF2968) SbcCD_C PF13558.1 CCF51947.1 - 0.00061 19.6 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit WEMBL PF05701.6 CCF51947.1 - 0.002 16.6 1.2 0.002 16.6 0.8 6.2 4 1 1 5 5 4 2 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 CCF51947.1 - 0.0021 17.3 17.7 0.19 10.8 1.3 5.1 5 1 0 5 5 5 2 Reovirus sigma C capsid protein DUF3584 PF12128.3 CCF51947.1 - 0.0023 15.3 101.4 0.011 13.1 5.5 4.3 4 0 0 4 4 4 4 Protein of unknown function (DUF3584) ABC_tran PF00005.22 CCF51947.1 - 0.061 13.6 0.0 0.061 13.6 0.0 6.5 4 3 0 5 5 4 0 ABC transporter AAA_13 PF13166.1 CCF51947.1 - 0.063 11.7 87.8 0.0079 14.7 3.9 6.3 5 2 1 6 6 6 0 AAA domain AAA_15 PF13175.1 CCF51947.1 - 0.26 10.2 20.0 0.0037 16.3 2.4 4.3 4 1 0 4 4 4 0 AAA ATPase domain NPV_P10 PF05531.7 CCF51947.1 - 3.8 7.8 38.1 0.069 13.4 1.3 7.5 6 3 1 7 7 6 0 Nucleopolyhedrovirus P10 protein ING PF12998.2 CCF51948.1 - 1.3e-14 54.3 0.4 7e-13 48.7 0.3 2.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCF51948.1 - 2e-07 30.5 9.2 3.5e-07 29.8 6.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF51948.1 - 0.03 13.6 2.2 0.053 12.8 1.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 CCF51948.1 - 0.071 13.1 3.8 0.12 12.3 2.6 1.3 1 0 0 1 1 1 0 RING-like domain Glyco_transf_20 PF00982.16 CCF51949.1 - 2e-153 511.2 0.0 3.3e-153 510.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCF51949.1 - 3.1e-68 229.2 0.0 6.7e-68 228.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase GMC_oxred_N PF00732.14 CCF51950.1 - 2.2e-50 171.5 0.0 3.3e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF51950.1 - 5.3e-38 130.5 0.1 8.4e-38 129.8 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 CCF51950.1 - 0.00016 21.6 0.0 0.00043 20.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF51950.1 - 0.00018 20.5 0.0 0.00037 19.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCF51950.1 - 0.0017 17.2 0.2 0.0073 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCF51950.1 - 0.0033 16.5 0.1 0.0064 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CCF51950.1 - 0.0054 16.8 0.3 0.46 10.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF51950.1 - 0.013 14.4 0.1 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 CCF51950.1 - 0.044 14.1 0.1 0.12 12.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF51950.1 - 0.073 12.9 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCF51950.1 - 0.11 11.4 0.2 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain COG5 PF10392.4 CCF51951.1 - 1e-18 67.5 6.3 1e-18 67.5 1.3 3.1 2 1 0 2 2 2 1 Golgi transport complex subunit 5 dCMP_cyt_deam_1 PF00383.17 CCF51952.1 - 1.6e-24 85.4 1.3 2.5e-24 84.8 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 CCF51952.1 - 0.00082 20.1 0.0 0.0017 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF51952.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCF51952.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCF51952.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DXP_redisom_C PF08436.7 CCF51953.1 - 0.01 15.6 0.6 0.015 15.1 0.4 1.4 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal rve PF00665.21 CCF51953.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain TFIIIC_sub6 PF10419.4 CCF51955.1 - 1.1e-09 37.5 0.0 1.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit Rpn3_C PF08375.6 CCF51956.1 - 1.2e-25 89.6 1.0 1.2e-25 89.6 0.7 2.5 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CCF51956.1 - 4.3e-19 68.7 1.5 6.9e-19 68.1 0.3 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CCF51956.1 - 0.018 14.8 0.1 0.055 13.2 0.0 1.9 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 NT-C2 PF10358.4 CCF51957.1 - 1.9e-12 46.8 0.1 7.7e-06 25.4 0.0 3.6 3 0 0 3 3 3 2 N-terminal C2 in EEIG1 and EHBP1 proteins NicO PF03824.11 CCF51957.1 - 2.5 7.3 6.3 4.4 6.5 4.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein PH_9 PF15410.1 CCF51958.1 - 3e-08 33.8 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCF51958.1 - 4.8e-08 33.1 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCF51958.1 - 0.0044 17.2 0.1 0.034 14.3 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain RAB3GAP2_N PF14655.1 CCF51958.1 - 0.87 8.5 4.4 2.2 7.1 3.1 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Bestrophin PF01062.16 CCF51959.1 - 7.4e-19 67.7 0.1 2.8e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel NUDIX PF00293.23 CCF51960.1 - 2.4e-09 36.9 0.0 3.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Peptidase_M16 PF00675.15 CCF51961.1 - 1.1e-42 145.2 2.5 8.7e-41 139.1 0.0 4.0 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCF51961.1 - 3.7e-33 114.7 0.1 3.6e-21 75.6 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain WHG PF13305.1 CCF51961.1 - 0.12 13.0 2.1 0.3 11.6 0.1 2.8 3 0 0 3 3 3 0 WHG domain Aa_trans PF01490.13 CCF51962.1 - 2.8e-32 111.7 37.1 3.2e-32 111.5 25.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2061 PF09834.4 CCF51962.1 - 0.0058 16.7 1.2 0.049 13.8 0.5 2.9 2 0 0 2 2 2 1 Predicted membrane protein (DUF2061) tRNA-synt_1b PF00579.20 CCF51963.1 - 1.7e-74 250.5 0.0 2.7e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FimP PF09766.4 CCF51964.1 - 7.5e-29 100.9 21.6 1.1e-28 100.3 15.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein DUF740 PF05340.7 CCF51964.1 - 1.6 6.9 5.9 2.4 6.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Afi1 PF07792.7 CCF51965.1 - 1.5e-40 138.5 0.0 2.7e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CCF51965.1 - 7e-32 109.4 0.0 1.3e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CCF51965.1 - 1.2e-09 37.1 0.0 0.0011 17.5 0.0 3.6 2 1 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.4 CCF51965.1 - 0.00069 18.9 0.0 0.65 9.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Peptidase_C50 PF03568.12 CCF51966.1 - 8.6e-82 274.8 0.0 7.7e-81 271.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase family C50 TPR_4 PF07721.9 CCF51966.1 - 0.0019 18.4 0.6 33 5.3 0.4 4.8 3 0 0 3 3 3 2 Tetratricopeptide repeat SNF2_N PF00176.18 CCF51967.1 - 3.9e-71 239.2 0.1 7.6e-71 238.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF51967.1 - 2.6e-12 46.4 0.0 7.5e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF51967.1 - 2.6e-09 37.1 0.0 6.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCF51967.1 - 2.5e-08 33.6 0.0 5.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CCF51967.1 - 8.1e-08 31.8 6.7 8.1e-08 31.8 4.6 2.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF51967.1 - 3.3e-07 30.2 7.8 3.3e-07 30.2 5.4 2.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF51967.1 - 1.2e-06 28.0 7.5 1.2e-06 28.0 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF51967.1 - 4.7e-06 26.3 9.1 4.7e-06 26.3 6.3 2.5 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CCF51967.1 - 0.00021 20.9 6.4 0.00021 20.9 4.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCF51967.1 - 0.0048 16.5 2.2 0.014 15.1 1.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DEAD_2 PF06733.10 CCF51967.1 - 0.017 14.5 0.1 0.11 11.9 0.0 2.3 1 1 0 1 1 1 0 DEAD_2 zf-RING_6 PF14835.1 CCF51967.1 - 0.039 13.7 3.7 0.099 12.4 2.5 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.1 CCF51967.1 - 0.14 11.6 13.3 0.2 11.1 1.3 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Ald_Xan_dh_C2 PF02738.13 CCF51968.1 - 2.9e-183 610.1 0.0 3.9e-183 609.6 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 CCF51968.1 - 1.5e-39 135.1 0.0 4.8e-39 133.5 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 CCF51968.1 - 1.5e-34 118.3 0.1 3e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 CCF51968.1 - 1.9e-26 91.9 0.0 5.1e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 CCF51968.1 - 3.9e-25 87.5 0.0 1.2e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 CCF51968.1 - 8.1e-07 28.7 0.0 2.4e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Velvet PF11754.3 CCF51969.1 - 1.1e-21 77.4 0.4 1.1e-21 77.4 0.3 3.0 3 1 0 3 3 3 1 Velvet factor CDK5_activator PF03261.10 CCF51969.1 - 0.055 12.7 4.1 0.039 13.3 0.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF3245 PF11595.3 CCF51970.1 - 0.041 14.1 3.5 0.061 13.6 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 CCF51970.1 - 0.37 8.7 4.1 0.52 8.2 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CCF51970.1 - 2.4 5.9 13.0 4 5.2 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 CCF51970.1 - 6.3 7.1 8.4 12 6.2 5.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Lgl_C PF08596.5 CCF51971.1 - 1.2e-21 76.6 0.0 7.6e-19 67.4 0.0 2.7 2 1 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCF51971.1 - 9.9e-06 25.2 0.1 0.0015 18.3 0.1 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat SPX PF03105.14 CCF51972.1 - 3.1e-27 96.0 0.5 4.2e-26 92.3 0.3 2.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.20 CCF51972.1 - 6.7e-08 32.0 5.7 1.1e-07 31.3 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF51972.1 - 1.5e-06 27.8 8.6 2.5e-06 27.2 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CCF51972.1 - 1.7e-06 27.7 6.4 3e-06 27.0 4.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CCF51972.1 - 2.5e-06 27.0 4.7 4e-06 26.3 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF51972.1 - 8.4e-06 25.7 7.8 1.4e-05 25.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF51972.1 - 0.00014 21.5 5.6 0.00026 20.6 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCF51972.1 - 0.0045 16.6 4.1 0.011 15.3 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CCF51972.1 - 0.0055 16.4 2.6 0.011 15.5 1.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CCF51972.1 - 0.0075 15.8 2.0 0.015 14.8 1.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CCF51972.1 - 0.44 10.7 5.6 1.3 9.1 3.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DEAD PF00270.24 CCF51973.1 - 3.2e-40 137.3 0.2 8.2e-21 74.2 0.2 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF51973.1 - 8.2e-19 67.2 0.0 1.9e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCF51973.1 - 6.2e-18 64.0 0.1 1.3e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCF51973.1 - 6.6e-07 29.3 0.0 6.6e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SbcCD_C PF13558.1 CCF51973.1 - 0.0043 16.9 0.3 1.3 8.9 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CCF51973.1 - 0.012 15.8 0.1 0.096 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCF51973.1 - 0.017 14.8 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Gemini_BL1 PF00845.14 CCF51973.1 - 9.7 5.4 9.0 9.4 5.5 4.0 2.0 2 0 0 2 2 2 0 Geminivirus BL1 movement protein HATPase_c PF02518.21 CCF51974.1 - 1.3e-29 102.1 0.4 2.8e-28 97.8 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCF51974.1 - 1.9e-25 89.0 0.1 7.1e-25 87.2 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 CCF51974.1 - 1e-22 80.2 1.4 5.9e-06 26.2 0.0 4.7 4 0 0 4 4 4 3 PAS fold HisKA PF00512.20 CCF51974.1 - 2.1e-19 69.2 0.1 9e-19 67.2 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 CCF51974.1 - 1.7e-16 60.4 0.0 4.2e-08 33.5 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 CCF51974.1 - 1.7e-12 47.2 1.4 1.7e-12 47.2 1.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 CCF51974.1 - 6.7e-12 45.1 0.2 0.00063 19.5 0.0 5.2 6 0 0 6 6 6 2 PAS fold PAS_8 PF13188.1 CCF51974.1 - 0.0031 17.3 0.0 6 6.8 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_7 PF12860.2 CCF51974.1 - 0.0038 17.2 0.8 3.1 7.8 0.0 3.6 3 0 0 3 3 3 1 PAS fold Malate_synthase PF01274.17 CCF51975.1 - 1.1e-209 696.8 0.0 1.2e-209 696.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Bromodomain PF00439.20 CCF51975.1 - 0.0081 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain HpcH_HpaI PF03328.9 CCF51975.1 - 0.036 12.9 0.0 0.08 11.8 0.0 1.6 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Thioredoxin PF00085.15 CCF51976.1 - 4.2e-28 97.0 0.1 4.6e-28 96.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCF51976.1 - 3.1e-08 33.7 0.3 6.1e-07 29.6 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF51976.1 - 1.2e-06 28.5 0.0 0.003 17.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CCF51976.1 - 1.6e-05 24.5 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCF51976.1 - 8.8e-05 22.1 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CCF51976.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CCF51976.1 - 0.00059 19.3 0.4 0.018 14.6 0.1 2.0 1 1 1 2 2 2 1 Redoxin HyaE PF07449.6 CCF51976.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 CCF51976.1 - 0.021 14.3 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin zf-AN1 PF01428.11 CCF51977.1 - 2.7e-18 65.5 20.5 8.4e-11 41.5 2.8 3.2 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CCF51977.1 - 0.00098 19.3 14.7 0.025 14.8 3.0 3.4 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain BDV_P10 PF06515.6 CCF51977.1 - 0.098 12.4 0.9 0.16 11.8 0.2 1.6 1 1 1 2 2 2 0 Borna disease virus P10 protein Gar1 PF04410.9 CCF51979.1 - 1e-34 119.2 0.2 7.9e-33 113.1 0.1 3.0 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Adaptin_N PF01602.15 CCF51981.1 - 1.9e-98 330.0 0.6 4.4e-84 282.6 0.9 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 CCF51981.1 - 1e-07 32.0 16.4 6.3e-05 23.1 1.0 6.4 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 CCF51981.1 - 7.3e-07 28.7 10.5 1.7 8.9 0.0 7.5 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.2 CCF51981.1 - 3.2e-05 23.8 0.3 0.00063 19.6 0.1 2.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TFIIA PF03153.8 CCF51981.1 - 0.0033 17.3 15.7 0.0033 17.3 10.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 CCF51981.1 - 1.9 7.9 25.3 3 7.2 17.5 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 CCF51981.1 - 9.5 5.3 29.2 14 4.8 20.3 1.2 1 0 0 1 1 1 0 NOA36 protein Kelch_4 PF13418.1 CCF51982.1 - 1e-42 143.6 16.3 1.3e-07 31.2 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CCF51982.1 - 6.9e-41 137.5 10.2 2.3e-09 37.1 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 CCF51982.1 - 5.7e-32 109.0 0.9 1.8e-05 24.1 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CCF51982.1 - 7.1e-30 102.4 5.8 1.5e-06 28.0 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCF51982.1 - 4.1e-28 96.0 12.4 7.8e-07 28.6 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CCF51982.1 - 2.2e-26 90.8 9.8 2.6e-05 24.1 0.0 6.4 3 1 3 6 6 6 5 Kelch motif PQQ_3 PF13570.1 CCF51982.1 - 0.0075 16.5 2.6 2.4 8.5 0.0 4.5 3 1 2 5 5 5 1 PQQ-like domain Ycf1 PF05758.7 CCF51983.1 - 0.066 10.9 12.4 0.078 10.6 8.6 1.0 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 CCF51983.1 - 0.093 12.1 29.7 0.18 11.1 20.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CCF51983.1 - 0.15 11.9 14.5 0.36 10.6 10.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CCF51983.1 - 0.16 10.1 40.8 0.2 9.8 28.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CCF51983.1 - 0.33 9.1 24.9 0.49 8.5 17.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CCF51983.1 - 0.53 8.8 12.2 0.66 8.5 8.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 CCF51983.1 - 0.66 8.1 17.6 0.97 7.6 12.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein IncA PF04156.9 CCF51983.1 - 1.2 8.6 20.2 2.2 7.8 14.0 1.3 1 0 0 1 1 1 0 IncA protein BTV_NS2 PF04514.7 CCF51983.1 - 2.3 7.0 16.2 4.3 6.1 11.2 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spore_coat_CotO PF14153.1 CCF51983.1 - 2.7 7.3 24.3 4.6 6.6 16.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4407 PF14362.1 CCF51983.1 - 4.7 6.0 21.4 8.3 5.2 14.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apt1 PF10351.4 CCF51983.1 - 5.8 5.6 13.3 0.063 12.1 3.9 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain adh_short PF00106.20 CCF51984.1 - 2.9e-20 72.8 0.6 4.1e-20 72.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF51984.1 - 9.8e-09 35.1 0.5 2.4e-08 33.8 0.3 1.5 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 CCF51984.1 - 0.00092 17.9 0.1 0.0034 16.1 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family SRP40_C PF05022.7 CCF51985.1 - 3e-29 101.3 2.2 7.3e-29 100.0 1.5 1.7 1 0 0 1 1 1 1 SRP40, C-terminal domain SDA1 PF05285.7 CCF51985.1 - 0.0023 17.3 17.3 0.0023 17.3 12.0 2.2 2 0 0 2 2 2 2 SDA1 DUF2046 PF09755.4 CCF51986.1 - 0.025 13.5 3.7 0.039 12.8 2.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) POP1 PF06978.6 CCF51987.1 - 5.6e-44 150.0 19.1 3.6e-43 147.4 13.2 2.4 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCF51987.1 - 6.7e-14 51.5 0.2 1.6e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 POPLD (NUC188) domain GPP34 PF05719.6 CCF51988.1 - 8.2e-73 244.8 0.0 1.1e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Bystin PF05291.6 CCF51989.1 - 3.1e-133 443.3 0.0 4.3e-133 442.8 0.0 1.1 1 0 0 1 1 1 1 Bystin WD40 PF00400.27 CCF51990.1 - 1.4e-66 218.1 18.1 6.5e-11 41.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCF51990.1 - 8.5e-27 93.1 4.6 1.4e-26 92.4 3.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 CCF51990.1 - 5.8e-05 22.0 0.4 0.11 11.2 0.1 2.8 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 CCF51990.1 - 0.00011 20.5 3.0 0.93 7.5 0.0 3.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCF51990.1 - 0.00071 17.9 0.2 0.5 8.5 0.0 2.6 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 CCF51990.1 - 0.0013 17.9 0.2 0.9 8.5 0.0 3.6 1 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Striatin PF08232.7 CCF51990.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Striatin family PQQ_2 PF13360.1 CCF51990.1 - 0.012 15.0 1.4 0.052 13.0 0.6 2.1 1 1 1 2 2 2 0 PQQ-like domain Use1 PF09753.4 CCF51990.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF3450 PF11932.3 CCF51990.1 - 0.22 10.7 1.1 0.37 10.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PfkB PF00294.19 CCF51992.1 - 8.9e-09 34.8 0.1 3.3e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF3759 PF12585.3 CCF51994.1 - 1.5e-34 117.7 6.0 1.8e-34 117.4 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Chromo PF00385.19 CCF51995.1 - 1.9e-13 49.8 2.7 1.9e-13 49.8 1.9 2.6 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 CCF51995.1 - 2.7e-08 33.5 1.4 2.9e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Chromo shadow domain PBP1_TM PF14812.1 CCF51995.1 - 0.094 13.0 40.0 0.072 13.3 5.7 3.7 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal gag_pre-integrs PF13976.1 CCF51997.1 - 1.9e-09 37.0 0.6 3.5e-09 36.1 0.4 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF51997.1 - 0.0036 17.3 0.0 0.0092 16.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Fels1 PF05666.6 CCF51997.1 - 0.13 11.6 0.2 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like RVT_2 PF07727.9 CCF51998.1 - 0.00033 19.7 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4589 PF15252.1 CCF51998.1 - 0.0094 15.7 0.3 0.016 15.0 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) MAGSP PF03082.9 CCF51998.1 - 0.11 11.8 0.2 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Male accessory gland secretory protein RVT_2 PF07727.9 CCF51999.1 - 2.7e-46 157.5 0.0 3.5e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.13 CCF52000.1 - 4.3e-20 72.1 0.0 3.9e-11 42.8 0.1 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain Myosin_head PF00063.16 CCF52001.1 - 4.2e-254 844.7 0.0 4.2e-254 844.7 0.0 3.4 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 CCF52001.1 - 1.9e-14 52.4 68.6 1.9e-14 52.4 47.6 4.9 3 1 1 4 4 4 4 Myosin tail Myosin_N PF02736.14 CCF52001.1 - 5.2e-06 26.0 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CCF52001.1 - 0.0038 16.9 0.0 0.023 14.4 0.0 2.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCF52001.1 - 0.11 12.6 0.0 0.11 12.6 0.0 4.6 3 1 2 5 5 5 0 AAA domain VRR_NUC PF08774.6 CCF52002.1 - 8.5e-20 70.6 0.1 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain CBFD_NFYB_HMF PF00808.18 CCF52003.1 - 7.1e-11 42.0 0.1 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cwf_Cwc_15 PF04889.7 CCF52003.1 - 1.5 8.4 12.3 2.5 7.7 8.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 CCF52003.1 - 9.5 5.1 18.0 12 4.8 12.5 1.3 1 1 0 1 1 1 0 BUD22 PNRC PF15365.1 CCF52004.1 - 7.7e-07 29.0 2.2 7.7e-07 29.0 1.5 4.5 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator Rad51 PF08423.6 CCF52005.1 - 8.3e-138 457.4 0.0 1e-137 457.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCF52005.1 - 8.5e-15 54.6 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CCF52005.1 - 1.6e-08 34.0 0.1 2.3e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CCF52005.1 - 2.3e-08 34.0 0.3 5.1e-08 32.9 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CCF52005.1 - 3.1e-07 29.7 0.0 5.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CCF52005.1 - 0.026 13.4 0.0 0.074 11.9 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CCF52005.1 - 0.059 12.1 1.2 0.15 10.8 0.4 1.8 1 1 1 2 2 2 0 PAXNEB protein HHH PF00633.18 CCF52005.1 - 0.12 12.1 0.1 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pyrid_oxidase_2 PF13883.1 CCF52006.1 - 9e-25 87.3 0.2 1.4e-24 86.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-UBR PF02207.15 CCF52007.1 - 3.8e-12 45.7 9.7 3.8e-12 45.7 6.7 3.7 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CCF52007.1 - 0.00029 20.4 1.7 0.00029 20.4 1.1 4.2 4 1 1 5 5 5 1 PHD-finger HAD PF12710.2 CCF52008.1 - 9.3e-14 52.0 0.0 4.5e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF52008.1 - 2.1e-11 44.6 0.1 0.00036 21.0 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCF52008.1 - 5.1e-10 38.7 0.0 1.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCF52008.1 - 6.5e-10 38.8 0.1 3.3e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF52008.1 - 0.00027 20.6 0.4 0.0061 16.1 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_S21 PF01165.15 CCF52010.1 - 0.069 12.5 0.6 0.17 11.3 0.4 1.6 1 0 0 1 1 1 0 Ribosomal protein S21 bZIP_1 PF00170.16 CCF52011.1 - 1.4e-05 24.9 16.7 0.00088 19.1 11.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 CCF52011.1 - 0.73 9.6 18.2 2.5 7.9 8.3 2.5 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 CCF52011.1 - 0.87 9.9 16.3 2.5 8.4 11.3 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 CCF52011.1 - 1.4 6.7 3.3 1.8 6.3 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Thiolase_N PF00108.18 CCF52012.1 - 5.6e-81 271.3 0.6 7.6e-81 270.9 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF52012.1 - 9e-49 163.9 0.6 2.3e-48 162.6 0.4 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCF52012.1 - 8.4e-06 25.4 0.7 8.4e-06 25.4 0.5 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TIM PF00121.13 CCF52013.1 - 5.2e-95 317.1 1.3 5.8e-95 316.9 0.9 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 CCF52013.1 - 0.00039 19.7 0.1 0.00092 18.5 0.0 1.5 1 1 0 1 1 1 1 CutC family Profilin PF00235.14 CCF52014.1 - 1.5e-35 121.9 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Profilin SAPS PF04499.10 CCF52015.1 - 1.2e-172 574.9 5.6 5.7e-172 572.6 0.0 3.2 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Armet PF10208.4 CCF52015.1 - 0.047 13.3 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding MCRS_N PF13325.1 CCF52015.1 - 0.89 9.0 6.1 0.79 9.1 2.1 2.4 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein EBV-NA3 PF05009.7 CCF52015.1 - 2.1 7.5 5.2 7.2 5.7 3.6 1.8 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) MOZ_SAS PF01853.13 CCF52016.1 - 1.7e-77 258.9 0.1 2.4e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 CCF52016.1 - 1.4e-17 63.1 24.8 6.9e-11 41.6 5.0 3.3 2 1 1 3 3 3 2 PHD-finger Prok-RING_1 PF14446.1 CCF52016.1 - 7 6.4 18.4 13 5.6 5.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Spc97_Spc98 PF04130.8 CCF52017.1 - 9.2e-48 162.8 0.0 1.4e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Pkinase PF00069.20 CCF52019.1 - 1.2e-73 247.4 0.0 1.5e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52019.1 - 2.3e-34 118.6 0.0 5.8e-34 117.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF52019.1 - 0.0002 20.4 0.0 0.00056 18.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCF52019.1 - 0.0031 16.6 0.1 0.007 15.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCF52019.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCF52019.1 - 0.038 12.8 0.3 0.057 12.2 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YukC PF10140.4 CCF52019.1 - 0.087 11.3 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pribosyltran_N PF13793.1 CCF52020.1 - 1.9e-43 146.8 0.1 2.6e-42 143.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCF52020.1 - 3e-35 121.6 1.0 1e-31 110.1 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCF52020.1 - 2.8e-14 52.9 1.6 4.4e-12 45.8 1.1 3.0 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCF52020.1 - 0.0062 15.7 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase 5-FTHF_cyc-lig PF01812.15 CCF52021.1 - 6e-36 123.9 0.0 7.1e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Peptidase_M17 PF00883.16 CCF52022.1 - 2.1e-112 375.0 0.1 2.7e-112 374.6 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CCF52022.1 - 8.6e-05 22.2 0.0 0.00044 20.0 0.0 2.2 2 1 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain WD40 PF00400.27 CCF52023.1 - 1.5e-47 157.8 8.2 3.7e-09 36.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 CCF52023.1 - 7.8e-44 148.4 0.2 1.3e-43 147.6 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 CCF52023.1 - 6.3e-33 113.7 0.0 8.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 PUL domain SH3_3 PF08239.6 CCF52023.1 - 0.033 14.3 1.2 0.081 13.1 0.9 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Grp1_Fun34_YaaH PF01184.14 CCF52025.1 - 1.2e-28 99.8 21.9 1.6e-28 99.4 15.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cytochrom_B561 PF03188.11 CCF52026.1 - 2e-12 47.1 6.3 2e-12 47.1 4.4 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 CCF52026.1 - 0.033 13.9 0.6 0.033 13.9 0.4 3.0 3 0 0 3 3 3 0 PepSY-associated TM helix Sdh_cyt PF01127.17 CCF52026.1 - 0.074 12.8 0.3 0.074 12.8 0.2 3.0 2 1 1 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2306 PF10067.4 CCF52026.1 - 0.14 12.3 12.5 0.24 11.5 0.2 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) RRM_1 PF00076.17 CCF52027.1 - 1.7e-30 104.4 0.0 1.6e-19 69.2 0.1 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52027.1 - 4.1e-23 81.1 0.0 9e-14 51.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF52027.1 - 4.3e-15 55.3 0.0 7.3e-07 28.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCF52027.1 - 2.8e-09 36.4 0.7 2.6e-06 26.9 0.1 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 CCF52027.1 - 6.3e-07 29.0 0.1 0.00083 19.0 0.0 2.6 2 0 0 2 2 2 2 Limkain b1 Pkinase PF00069.20 CCF52029.1 - 2.7e-60 203.7 0.0 2e-35 122.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52029.1 - 1.2e-25 90.0 0.0 4.4e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCF52029.1 - 1.4e-14 54.3 1.5 8.9e-14 51.7 1.0 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CCF52029.1 - 0.044 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PX PF00787.19 CCF52029.1 - 0.11 12.3 0.0 0.43 10.3 0.0 2.1 2 1 0 2 2 2 0 PX domain Metallophos PF00149.23 CCF52030.1 - 7.2e-09 35.3 0.1 5.7e-08 32.3 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP_transf PF09830.4 CCF52032.1 - 1.1e-14 53.9 0.0 2.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase HHH PF00633.18 CCF52032.1 - 0.03 14.0 0.4 21 5.0 0.0 3.3 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF4647 PF15504.1 CCF52032.1 - 0.03 13.1 0.1 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) MPC PF03650.8 CCF52033.1 - 4.7e-37 126.5 0.2 5.3e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) TPP1 PF10341.4 CCF52033.1 - 0.061 13.3 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Hexapep PF00132.19 CCF52034.1 - 1.2e-09 37.2 9.2 0.00084 18.7 0.1 4.3 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCF52034.1 - 0.00016 21.1 9.5 0.0012 18.4 0.2 3.6 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 CCF52034.1 - 0.066 11.7 1.4 0.3 9.5 0.5 2.2 1 1 1 2 2 2 0 L-fucokinase FTHFS PF01268.14 CCF52035.1 - 1.1e-259 862.1 0.7 1.1e-259 862.1 0.5 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCF52035.1 - 9.8e-66 219.7 0.3 9.8e-66 219.7 0.2 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCF52035.1 - 1.8e-34 118.2 0.1 4.7e-34 116.9 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ribosomal_L18e PF00828.14 CCF52036.1 - 6e-33 113.9 0.2 8.2e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L16 PF00252.13 CCF52037.1 - 7.9e-32 109.8 0.1 1.1e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e IBR PF01485.16 CCF52038.1 - 1e-19 70.1 43.8 2e-11 43.5 2.6 4.7 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 CCF52038.1 - 0.00014 21.4 3.4 0.00014 21.4 2.3 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF52038.1 - 0.00034 20.3 3.8 0.00034 20.3 2.6 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF52038.1 - 0.0015 18.4 3.6 0.0015 18.4 2.5 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52038.1 - 0.0017 18.0 4.8 0.0017 18.0 3.3 4.1 3 1 1 4 4 4 2 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCF52038.1 - 0.012 15.3 19.3 0.028 14.1 0.4 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCF52038.1 - 0.052 13.4 26.3 0.22 11.4 0.7 4.8 3 2 1 4 4 4 0 zinc finger of C3HC4-type, RING DUF1488 PF07369.6 CCF52038.1 - 0.098 12.5 0.1 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-RING_4 PF14570.1 CCF52038.1 - 0.62 9.6 30.1 0.45 10.1 1.4 3.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain AA_permease PF00324.16 CCF52039.1 - 1e-124 416.5 41.7 1.2e-124 416.3 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF52039.1 - 2.2e-36 125.3 45.2 2.9e-36 124.9 31.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF221 PF02714.10 CCF52040.1 - 1.3e-98 329.8 19.9 2.2e-98 329.1 13.8 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCF52040.1 - 2.5e-32 111.6 0.4 2.5e-32 111.6 0.3 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCF52040.1 - 7.3e-08 32.8 0.0 2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) Tbf5 PF06331.7 CCF52041.1 - 1.3e-21 76.0 0.1 1.4e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF2381 PF09544.5 CCF52041.1 - 0.11 11.5 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DEAD PF00270.24 CCF52042.1 - 4.9e-41 140.0 0.1 7.3e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF52042.1 - 6.4e-24 83.6 0.1 1.3e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCF52042.1 - 0.0058 15.7 0.1 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Pam17 PF08566.5 CCF52043.1 - 7.4e-68 227.6 0.0 9.5e-68 227.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 RrnaAD PF00398.15 CCF52044.1 - 5.4e-18 64.9 0.0 1.3e-17 63.7 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ribosomal_60s PF00428.14 CCF52044.1 - 9.4 6.7 11.9 4.2 7.8 5.3 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DnaJ PF00226.26 CCF52045.1 - 9.3e-21 73.3 0.3 9.3e-21 73.3 0.2 2.7 3 0 0 3 3 3 1 DnaJ domain Ist1 PF03398.9 CCF52046.1 - 4e-53 179.2 1.9 5.4e-53 178.7 1.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DNA_primase_S PF01896.14 CCF52047.1 - 1.5e-53 180.5 0.0 2.8e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Clr2 PF10383.4 CCF52048.1 - 1.5e-27 96.2 0.0 5.4e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 WW PF00397.21 CCF52048.1 - 1.2e-08 34.6 2.8 2.7e-08 33.5 1.9 1.6 1 0 0 1 1 1 1 WW domain PWWP PF00855.12 CCF52048.1 - 0.0081 16.3 0.0 0.042 14.0 0.0 2.3 2 1 0 2 2 2 1 PWWP domain WD40 PF00400.27 CCF52049.1 - 2.9e-27 93.5 18.4 5.4e-08 32.4 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PBP PF01161.15 CCF52050.1 - 4.5e-14 52.5 0.1 7.4e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribonuclease_P PF00825.13 CCF52053.1 - 0.057 13.3 1.6 0.098 12.5 1.1 1.4 1 1 0 1 1 1 0 Ribonuclease P Ribosomal_L7Ae PF01248.21 CCF52054.1 - 4.6e-24 83.7 0.2 1e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCF52054.1 - 0.0028 17.4 0.0 0.0059 16.4 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 DUF572 PF04502.8 CCF52054.1 - 0.1 11.7 5.9 0.12 11.5 4.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ATG11 PF10377.4 CCF52055.1 - 3.3e-32 111.1 2.6 8.2e-32 109.8 0.1 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 DUF4424 PF14415.1 CCF52055.1 - 1.6 8.1 4.4 23 4.3 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4424) zf-CCHC PF00098.18 CCF52056.1 - 0.0011 18.8 5.6 0.0011 18.8 3.9 2.1 2 0 0 2 2 2 1 Zinc knuckle TetR_C PF02909.12 CCF52056.1 - 0.11 12.1 0.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain PH_3 PF14593.1 CCF52057.1 - 0.048 13.5 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 PH domain FHA PF00498.21 CCF52058.1 - 2.5e-13 49.9 0.0 5.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CCF52058.1 - 4e-08 32.9 12.4 6.5e-08 32.2 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCF52058.1 - 8e-05 22.6 4.4 0.00015 21.8 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCF52058.1 - 0.01 15.4 11.6 0.019 14.6 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF52058.1 - 0.013 15.3 4.1 0.022 14.5 2.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CCF52058.1 - 0.13 12.0 10.6 0.23 11.2 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCF52058.1 - 0.57 10.2 14.1 0.99 9.4 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dicty_REP PF05086.7 CCF52058.1 - 0.94 7.1 0.2 1.3 6.6 0.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PHD PF00628.24 CCF52058.1 - 1.6 8.5 7.0 2.8 7.6 4.8 1.4 1 0 0 1 1 1 0 PHD-finger RR_TM4-6 PF06459.7 CCF52059.1 - 4.9 6.9 8.7 5.8 6.7 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-RING_2 PF13639.1 CCF52060.1 - 9.2e-11 41.4 2.3 9.1e-09 35.0 0.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCF52060.1 - 1.4e-09 37.9 0.3 2e-07 31.0 0.2 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCF52060.1 - 3.3e-06 26.6 3.2 3.6e-05 23.3 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF52060.1 - 2e-05 24.3 0.6 8.4e-05 22.3 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCF52060.1 - 2.6e-05 23.7 3.5 7.6e-05 22.2 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52060.1 - 0.00034 20.2 2.4 0.00076 19.1 0.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCF52060.1 - 0.00042 20.2 1.3 0.00042 20.2 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1469 PF07332.6 CCF52060.1 - 0.048 13.3 0.2 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) zf-RING_4 PF14570.1 CCF52060.1 - 0.076 12.6 1.6 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CCF52060.1 - 0.64 10.0 8.9 22 5.0 3.4 3.2 2 1 0 2 2 2 0 FANCL C-terminal domain GCFC PF07842.7 CCF52061.1 - 4.8e-64 216.3 0.2 6.6e-64 215.9 0.2 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 CCF52061.1 - 1.1e-12 48.0 8.6 1.1e-12 48.0 6.0 2.8 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 CCF52061.1 - 9e-11 41.3 0.5 9e-11 41.3 0.3 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CCF52061.1 - 0.0077 16.0 0.1 0.0077 16.0 0.0 2.7 2 1 1 3 3 3 1 DExH-box splicing factor binding site HSF_DNA-bind PF00447.12 CCF52062.1 - 1.2e-35 121.7 0.6 2.6e-35 120.7 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CCF52062.1 - 7.3e-24 83.9 0.0 1.8e-23 82.6 0.0 1.7 2 0 0 2 2 2 1 Response regulator receiver domain Ribosomal_S15 PF00312.17 CCF52062.1 - 0.18 11.5 0.5 0.45 10.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S15 Mcp5_PH PF12814.2 CCF52063.1 - 4e-42 143.0 0.1 1.2e-41 141.4 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 CCF52063.1 - 3.4e-05 23.9 0.0 8.9e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.12 CCF52064.1 - 3.4e-11 42.8 0.0 7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCF52064.1 - 8.1e-08 32.3 1.1 2.4e-07 30.8 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) ABC_tran PF00005.22 CCF52067.1 - 3.6e-33 114.7 0.1 6.7e-16 58.8 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CCF52067.1 - 3.8e-14 51.9 5.8 3.8e-14 51.9 4.0 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CCF52067.1 - 2.5e-13 50.6 6.5 0.0047 16.9 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 CCF52067.1 - 2.5e-10 39.9 6.1 0.001 18.3 0.2 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCF52067.1 - 1.7e-07 30.6 3.1 2 7.3 0.1 4.7 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 CCF52067.1 - 8.7e-07 29.1 0.0 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CCF52067.1 - 9.1e-06 25.8 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CCF52067.1 - 1.9e-05 24.0 0.8 0.04 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CCF52067.1 - 1.9e-05 23.8 2.0 0.19 10.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4 PF00037.22 CCF52067.1 - 2.2e-05 23.8 3.0 2.2e-05 23.8 2.1 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_17 PF13207.1 CCF52067.1 - 9.2e-05 23.2 0.5 0.75 10.6 0.1 2.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF52067.1 - 0.00014 21.9 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CCF52067.1 - 0.00017 22.0 0.0 0.28 11.7 0.0 2.9 3 0 0 3 3 2 1 Miro-like protein NACHT PF05729.7 CCF52067.1 - 0.00029 20.5 1.3 0.033 13.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CCF52067.1 - 0.00039 20.5 0.3 0.16 12.1 0.0 3.2 3 0 0 3 3 2 1 RNA helicase VirE PF05272.6 CCF52067.1 - 0.00044 19.7 0.0 0.38 10.1 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E AAA_25 PF13481.1 CCF52067.1 - 0.0012 18.2 0.0 0.93 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CCF52067.1 - 0.0013 18.4 0.9 0.36 10.5 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCF52067.1 - 0.0013 18.6 0.7 0.12 12.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCF52067.1 - 0.0016 18.7 0.6 0.7 10.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 CCF52067.1 - 0.0024 18.2 9.7 0.0072 16.6 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 CCF52067.1 - 0.0024 17.6 11.6 0.0065 16.2 1.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 CCF52067.1 - 0.0026 17.5 12.0 0.0063 16.3 8.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.17 CCF52067.1 - 0.0032 16.9 2.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 CCF52067.1 - 0.0038 16.8 0.2 0.059 12.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 CCF52067.1 - 0.0045 16.8 0.0 3.9 7.4 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 CCF52067.1 - 0.0084 16.0 0.3 1.6 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.1 CCF52067.1 - 0.012 15.8 1.5 0.012 15.8 1.0 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCF52067.1 - 0.022 14.5 1.8 0.022 14.5 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.17 CCF52067.1 - 0.028 13.2 0.2 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 CCF52067.1 - 0.029 14.6 1.3 0.029 14.6 0.9 2.6 2 1 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 CCF52067.1 - 0.038 14.7 0.2 0.038 14.7 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 CCF52067.1 - 0.043 13.7 1.4 16 5.4 0.0 3.4 2 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 CCF52067.1 - 0.073 12.4 0.6 6.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 CCF52067.1 - 0.085 12.4 0.6 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CCF52067.1 - 0.093 11.3 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein HflK_N PF12221.3 CCF52067.1 - 0.097 12.4 0.1 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Thymidylate_kin PF02223.12 CCF52067.1 - 0.12 11.7 0.6 8 5.7 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.9 CCF52067.1 - 0.18 11.5 2.2 1.2 8.9 0.0 2.9 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 CCF52067.1 - 0.18 10.5 0.1 1 8.0 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Fer4_8 PF13183.1 CCF52067.1 - 0.36 10.9 9.5 0.3 11.1 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 CCF52067.1 - 0.47 10.1 2.0 9.4 5.9 0.0 3.0 3 0 0 3 3 3 0 NTPase Fer4_2 PF12797.2 CCF52067.1 - 0.51 10.3 12.7 0.23 11.4 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain PduV-EutP PF10662.4 CCF52067.1 - 0.73 9.3 2.8 1.9 7.9 0.0 2.9 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ATG27 PF09451.5 CCF52069.1 - 6e-80 268.3 0.0 6.8e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 TTL PF03133.10 CCF52070.1 - 1e-46 159.2 0.0 2.1e-45 154.9 0.0 2.1 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Nro1 PF12753.2 CCF52070.1 - 0.12 11.2 2.8 0.18 10.7 2.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 INCENP_ARK-bind PF03941.10 CCF52071.1 - 9.2e-08 31.8 0.1 9.2e-08 31.8 0.0 2.9 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Acyltransferase PF01553.16 CCF52073.1 - 1.3e-11 44.0 0.0 2.2e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase DUF617 PF04759.8 CCF52074.1 - 0.043 13.4 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Wbp11 PF09429.5 CCF52075.1 - 6.9e-13 48.3 17.6 6.9e-13 48.3 12.2 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.2 CCF52075.1 - 2.1e-11 44.1 5.8 2.1e-11 44.1 4.0 3.8 2 2 0 2 2 2 1 mRNA biogenesis factor APG6 PF04111.7 CCF52075.1 - 0.25 10.3 7.4 0.43 9.5 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2360 PF10152.4 CCF52075.1 - 1.2 9.4 17.7 2.5 8.3 4.3 3.0 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF724 PF05266.9 CCF52075.1 - 6.1 6.4 8.9 12 5.5 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Peptidase_C48 PF02902.14 CCF52076.1 - 4.5e-09 36.2 0.0 6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRAM PF02893.15 CCF52077.1 - 4e-18 64.7 0.1 3.4e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 GRAM domain DASH_Spc19 PF08287.6 CCF52078.1 - 2.1e-26 92.3 14.3 2.1e-26 92.3 9.9 1.6 2 0 0 2 2 2 1 Spc19 Gp-FAR-1 PF05823.7 CCF52078.1 - 0.067 13.1 8.9 1.2 9.0 0.2 2.5 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MVP_shoulder PF11978.3 CCF52078.1 - 0.088 12.6 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Shoulder domain YfcL PF08891.6 CCF52078.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.1 3 1 0 3 3 3 0 YfcL protein Complex1_LYR_2 PF13233.1 CCF52078.1 - 6.2 7.3 13.7 1.6 9.2 5.2 2.3 2 0 0 2 2 2 0 Complex1_LYR-like Peptidase_S49_N PF08496.5 CCF52078.1 - 7.9 6.2 10.6 63 3.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal p47_phox_C PF08944.6 CCF52078.1 - 9.3 6.5 9.4 0.25 11.5 0.3 2.7 2 1 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain BP28CT PF08146.7 CCF52081.1 - 1.5e-38 131.9 2.5 5e-38 130.2 1.2 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCF52081.1 - 4.7e-18 65.3 6.0 4.7e-18 65.3 4.2 4.5 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.1 CCF52081.1 - 0.0016 18.8 18.3 0.022 15.2 0.6 6.6 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.17 CCF52081.1 - 0.0019 18.1 2.2 0.19 11.9 0.1 4.6 3 0 0 3 3 3 1 HEAT repeat FCD PF07729.7 CCF52082.1 - 0.016 15.4 2.0 7 6.9 0.0 3.3 3 0 0 3 3 3 0 FCD domain DUF2236 PF09995.4 CCF52083.1 - 1.9e-25 89.5 0.2 1.2e-24 86.9 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Rad1 PF02144.11 CCF52084.1 - 3e-94 314.8 0.0 3.7e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 His_Phos_2 PF00328.17 CCF52085.1 - 9.8e-33 113.9 0.0 1.2e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Vpu PF00558.14 CCF52086.1 - 0.5 9.9 4.1 0.35 10.4 1.9 1.5 1 1 1 2 2 2 0 Vpu protein RVT_2 PF07727.9 CCF52088.1 - 1.1e-51 175.2 0.2 6.9e-51 172.5 0.2 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 CCF52089.1 - 9.2e-10 38.8 0.5 1.2e-09 38.4 0.4 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CAP59_mtransfer PF11735.3 CCF52090.1 - 5.3e-68 228.8 0.0 7.3e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Sugar_tr PF00083.19 CCF52091.1 - 2e-112 376.0 15.9 2.3e-112 375.8 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF52091.1 - 1.2e-23 83.3 40.0 2.5e-19 69.2 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCF52091.1 - 0.0089 14.2 0.7 0.015 13.4 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YqhR PF11085.3 CCF52091.1 - 0.057 12.9 0.3 0.057 12.9 0.2 2.9 3 1 0 3 3 3 0 Conserved membrane protein YqhR AgrB PF04647.10 CCF52091.1 - 0.43 9.6 0.0 0.43 9.6 0.0 3.0 2 1 1 3 3 3 0 Accessory gene regulator B PAN_4 PF14295.1 CCF52093.1 - 2.3e-05 23.9 0.4 4.7e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CCF52093.1 - 0.0093 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 PAN domain Tet_JBP PF12851.2 CCF52093.1 - 0.049 12.9 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_88 PF07470.8 CCF52094.1 - 2.5e-14 53.0 1.9 4.4e-14 52.2 1.3 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AMP-binding PF00501.23 CCF52094.1 - 3.3e-06 25.7 0.0 5.6e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Zn_clus PF00172.13 CCF52095.1 - 4.9e-06 26.3 10.0 9e-06 25.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.14 CCF52096.1 - 2e-39 134.9 0.4 4e-39 133.9 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CCF52096.1 - 1.9e-23 83.0 0.1 3.8e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CCF52096.1 - 9.8e-12 44.2 0.2 3.1e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CCF52096.1 - 0.00036 20.6 0.9 0.024 14.7 0.3 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain G_glu_transpept PF01019.16 CCF52097.1 - 1e-147 492.7 0.3 1.1e-147 492.5 0.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PNK3P PF08645.6 CCF52098.1 - 1.2e-47 161.3 0.0 2.3e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CCF52098.1 - 4e-28 98.0 0.2 4.6e-27 94.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCF52098.1 - 2.3e-07 30.1 0.0 4.9e-05 22.5 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin KTI12 PF08433.5 CCF52098.1 - 0.0089 15.2 4.2 0.14 11.3 1.6 2.2 1 1 1 2 2 2 1 Chromatin associated protein KTI12 SRPRB PF09439.5 CCF52098.1 - 0.0089 15.2 0.0 0.021 14.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCF52098.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 CCF52098.1 - 0.011 15.6 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CCF52098.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CCF52098.1 - 0.025 15.3 0.0 0.061 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 CCF52098.1 - 0.039 13.0 0.3 1.5 7.8 0.0 2.1 1 1 1 2 2 2 0 6-phosphofructo-2-kinase Trehalase PF01204.13 CCF52099.1 - 2e-113 379.7 2.6 1.2e-102 344.2 0.0 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 CCF52099.1 - 0.0011 17.7 1.6 0.0099 14.6 1.1 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_luciferase PF00296.15 CCF52102.1 - 1.4e-67 227.9 0.3 1.9e-67 227.6 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Mito_carr PF00153.22 CCF52103.1 - 1.7e-51 171.9 7.5 8.9e-17 60.5 0.2 4.3 4 1 0 4 4 4 4 Mitochondrial carrier protein Peptidase_M28 PF04389.12 CCF52104.1 - 1.1e-13 51.3 0.1 2e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCF52104.1 - 1.3e-11 44.1 0.0 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCF52104.1 - 5.2e-10 38.9 0.3 1.1e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 PA domain Adaptin_N PF01602.15 CCF52104.1 - 0.096 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Val_tRNA-synt_C PF10458.4 CCF52104.1 - 3 7.9 5.9 8.6 6.5 0.2 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm PALP PF00291.20 CCF52105.1 - 7.8e-47 159.9 0.0 1.3e-45 155.9 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 CCF52105.1 - 0.13 11.7 0.7 0.8 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) FAM91_C PF14648.1 CCF52106.1 - 0.03 13.1 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF1359 PF07097.6 CCF52106.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1359) IMS PF00817.15 CCF52107.1 - 1.4e-38 131.9 0.0 3.3e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCF52107.1 - 7.1e-15 55.0 0.0 1.6e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 CCF52107.1 - 1.7e-07 31.0 9.8 0.0079 16.1 1.2 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) BRCT PF00533.21 CCF52107.1 - 5.6e-05 23.2 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 CCF52107.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) IMS_HHH PF11798.3 CCF52107.1 - 0.089 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif Aa_trans PF01490.13 CCF52108.1 - 1e-79 267.9 12.6 1.3e-79 267.6 8.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 60KD_IMP PF02096.15 CCF52108.1 - 0.24 11.0 5.7 5.9 6.5 0.2 3.3 3 0 0 3 3 3 0 60Kd inner membrane protein PetN PF03742.9 CCF52109.1 - 0.14 11.7 0.2 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 PetN His_Phos_2 PF00328.17 CCF52110.1 - 5.1e-18 65.5 0.0 3.1e-17 62.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4167 PF13763.1 CCF52110.1 - 0.094 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) zf-DHHC PF01529.15 CCF52111.1 - 3.5e-29 101.4 0.0 3.5e-29 101.4 0.0 2.5 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF2754 PF10953.3 CCF52111.1 - 0.15 12.1 0.2 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) zf-C2HC5 PF06221.8 CCF52112.1 - 2.9e-17 62.1 2.2 4.7e-17 61.4 1.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CHCH PF06747.8 CCF52113.1 - 3.1e-05 23.7 1.2 0.0028 17.5 0.1 2.8 2 1 1 3 3 3 2 CHCH domain UCR_hinge PF02320.11 CCF52113.1 - 0.004 17.0 1.0 0.004 17.0 0.7 2.7 1 1 1 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 CCF52113.1 - 0.066 12.9 8.3 2.8 7.8 2.3 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 CCF52113.1 - 0.16 11.9 7.0 1.4 9.0 0.1 2.5 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 CCF52113.1 - 0.31 11.1 3.7 4.3 7.4 0.7 2.6 1 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.3 CCF52113.1 - 0.7 10.0 3.5 15 5.8 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) DUF1903 PF08991.5 CCF52113.1 - 1.3 9.2 8.2 6.7 6.9 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1903) Glyco_hydro_47 PF01532.15 CCF52115.1 - 9.2e-154 512.4 0.0 1.1e-153 512.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Urm1 PF09138.6 CCF52116.1 - 5.3e-33 113.0 0.0 6e-33 112.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CCF52116.1 - 9.2e-05 22.8 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 ThiS family DUF3290 PF11694.3 CCF52116.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4430 PF14478.1 CCF52116.1 - 0.057 13.4 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) ThiS-like PF14453.1 CCF52116.1 - 0.068 13.0 0.6 0.11 12.3 0.4 1.4 1 1 0 1 1 1 0 ThiS-like ubiquitin TrkA_C PF02080.16 CCF52116.1 - 0.1 12.2 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain IQ PF00612.22 CCF52117.1 - 0.00015 21.0 0.7 0.00038 19.8 0.5 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SR-25 PF10500.4 CCF52117.1 - 5.2 6.4 33.0 0.028 13.8 10.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3325 PF11804.3 CCF52119.1 - 0.0093 15.8 0.7 0.013 15.4 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3325) APC10 PF03256.11 CCF52119.1 - 0.07 12.7 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) CheD PF03975.8 CCF52120.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.5 1 1 0 1 1 1 0 CheD chemotactic sensory transduction MS_channel PF00924.13 CCF52123.1 - 1.8e-23 82.9 1.9 3.6e-23 81.9 1.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 CCF52123.1 - 0.016 14.4 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CCF52123.1 - 0.044 13.9 0.3 0.11 12.7 0.2 1.6 1 1 0 1 1 1 0 EF-hand domain pair DUF4328 PF14219.1 CCF52123.1 - 0.29 10.3 17.8 0.011 15.0 6.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) AMP-binding PF00501.23 CCF52124.1 - 4.1e-70 236.2 0.0 4.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF52124.1 - 1.4e-17 64.3 0.0 4.1e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MAPEG PF01124.13 CCF52125.1 - 1.5e-13 50.5 3.7 1.7e-13 50.2 2.5 1.1 1 0 0 1 1 1 1 MAPEG family AGTRAP PF06396.6 CCF52125.1 - 0.007 16.0 0.8 0.011 15.4 0.5 1.2 1 0 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Fe-ADH PF00465.14 CCF52126.1 - 2.1e-93 312.8 0.0 2.7e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CCF52126.1 - 8.4e-13 48.2 0.0 6e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Abhydrolase_5 PF12695.2 CCF52127.1 - 0.091 12.5 0.1 0.31 10.7 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.16 CCF52128.1 - 6.6e-46 156.4 0.0 8.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_H_2 PF13482.1 CCF52128.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 1 0 1 1 1 0 RNase_H superfamily DUF294_C PF10335.4 CCF52130.1 - 0.01 15.4 2.9 0.013 15.1 1.3 1.5 1 1 1 2 2 2 0 Putative nucleotidyltransferase substrate binding domain adh_short PF00106.20 CCF52131.1 - 6.2e-27 94.5 0.1 8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF52131.1 - 1.7e-19 70.5 0.0 2.2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF52131.1 - 6.1e-10 39.0 0.1 8.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCF52131.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCF52131.1 - 0.022 14.7 0.9 0.04 13.9 0.2 1.7 2 1 0 2 2 2 0 NADH(P)-binding Glyco_transf_28 PF03033.15 CCF52131.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Eno-Rase_NADH_b PF12242.3 CCF52131.1 - 0.1 12.3 1.3 0.23 11.2 0.9 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADK PF00406.17 CCF52132.1 - 3.8e-46 156.7 0.0 4.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCF52132.1 - 6.2e-12 44.9 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCF52132.1 - 4.6e-06 26.5 0.0 4.9e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF52132.1 - 9.6e-06 26.4 0.0 1.3e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF52132.1 - 3.8e-05 22.8 0.0 0.0089 15.1 0.0 2.6 2 1 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CCF52132.1 - 5.1e-05 23.5 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 CCF52132.1 - 0.14 11.2 0.0 5.8 5.9 0.0 2.4 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Ion_trans_2 PF07885.11 CCF52133.1 - 3.4e-30 103.5 33.8 1.1e-15 57.0 5.5 3.5 4 0 0 4 4 4 2 Ion channel Ion_trans PF00520.26 CCF52133.1 - 0.0014 17.9 11.9 0.064 12.5 4.3 2.7 2 0 0 2 2 2 2 Ion transport protein DUF106 PF01956.11 CCF52133.1 - 0.015 14.8 0.2 0.83 9.1 0.0 2.7 3 0 0 3 3 3 0 Integral membrane protein DUF106 RVT_1 PF00078.22 CCF52137.1 - 7.7e-07 28.6 0.3 0.011 15.1 0.1 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2946 PF11162.3 CCF52137.1 - 0.094 12.9 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Sulfate_transp PF00916.15 CCF52141.1 - 1.2e-75 254.1 7.8 1.2e-75 254.1 5.4 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCF52141.1 - 1.1e-31 108.3 1.9 1.1e-31 108.3 1.3 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCF52141.1 - 1.3e-10 40.6 0.0 2.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain Peptidase_M24 PF00557.19 CCF52143.1 - 3e-41 141.2 0.0 4.2e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCF52143.1 - 1.2e-23 84.0 0.0 8.7e-22 78.0 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain SPDY PF03771.11 CCF52143.1 - 0.16 11.4 0.8 0.51 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF317) AdoHcyase PF05221.12 CCF52144.1 - 5.3e-135 448.5 0.0 6e-135 448.3 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCF52144.1 - 2.6e-85 284.2 1.5 4.4e-85 283.5 1.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCF52144.1 - 1e-10 41.0 0.1 3.8e-10 39.1 0.0 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CCF52144.1 - 0.00033 20.0 0.1 0.00054 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCF52144.1 - 0.0029 17.5 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 CCF52144.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CCF52144.1 - 0.059 12.4 0.3 0.27 10.3 0.2 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Septin PF00735.13 CCF52145.1 - 5.9e-125 415.9 0.6 5.9e-125 415.9 0.4 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCF52145.1 - 4.1e-07 29.9 0.0 9.2e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCF52145.1 - 5.8e-06 25.5 0.0 1.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCF52145.1 - 3.8e-05 23.2 0.1 0.0022 17.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCF52145.1 - 0.00028 20.7 1.5 0.067 13.0 0.0 3.0 2 1 1 3 3 3 1 Dynamin family Ras PF00071.17 CCF52145.1 - 0.00054 19.3 1.2 0.0063 15.9 0.0 2.7 2 1 0 2 2 2 1 Ras family AIG1 PF04548.11 CCF52145.1 - 0.0018 17.4 2.0 0.003 16.6 0.0 2.4 3 1 1 4 4 4 1 AIG1 family AAA_22 PF13401.1 CCF52145.1 - 0.0025 17.9 0.7 0.012 15.7 0.0 2.4 3 2 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CCF52145.1 - 0.0027 17.2 0.3 0.008 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA-like domain Miro PF08477.8 CCF52145.1 - 0.0059 17.0 0.0 0.067 13.6 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 CCF52145.1 - 0.0076 16.2 0.5 0.065 13.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 CCF52145.1 - 0.0082 16.4 8.3 0.021 15.1 0.6 2.6 2 1 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 CCF52145.1 - 0.012 15.3 1.4 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 CCF52145.1 - 0.013 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 CCF52145.1 - 0.041 13.4 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CCF52145.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CCF52145.1 - 0.058 12.8 0.4 9.3 5.7 0.0 3.3 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 CCF52145.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CCF52145.1 - 0.33 10.5 5.7 0.62 9.6 3.9 1.4 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 CCF52145.1 - 2.9 6.9 11.6 1.2 8.2 6.0 1.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit Tht1 PF04163.7 CCF52146.1 - 9.7e-08 30.8 4.5 5.2e-06 25.1 0.2 2.1 2 0 0 2 2 2 2 Tht1-like nuclear fusion protein Spc42p PF11544.3 CCF52146.1 - 0.034 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p MRG PF05712.8 CCF52147.1 - 6.1e-53 178.6 0.0 9.3e-53 178.0 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CCF52147.1 - 5e-10 38.9 1.0 6.6e-10 38.5 0.2 1.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 CCF52147.1 - 0.22 11.2 1.9 0.4 10.3 0.5 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Secretin_N_2 PF07655.8 CCF52147.1 - 0.46 10.8 4.3 1 9.8 3.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain AMP-binding PF00501.23 CCF52148.1 - 1.5e-82 277.1 0.0 2.1e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sec63 PF02889.11 CCF52149.1 - 2.9e-179 595.0 0.1 1.4e-96 323.4 0.0 2.6 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCF52149.1 - 3.8e-48 163.1 0.0 2e-28 99.0 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CCF52149.1 - 6.3e-14 52.2 0.0 1.4e-09 38.0 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCF52149.1 - 1.8e-12 46.9 0.0 5.3e-08 32.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCF52149.1 - 1.4e-05 25.1 0.3 0.0055 16.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.11 CCF52149.1 - 0.038 13.2 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PHD PF00628.24 CCF52150.1 - 6.2e-07 29.0 14.5 1.1e-06 28.2 10.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF52150.1 - 0.0013 17.9 6.6 0.0025 17.1 4.6 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CCF52150.1 - 0.0062 16.8 0.0 0.0062 16.8 0.0 4.4 3 2 0 3 3 3 1 SET domain HEAT_2 PF13646.1 CCF52151.1 - 5.2e-06 26.6 12.5 0.00018 21.6 0.1 5.5 6 1 0 6 6 6 2 HEAT repeats Anticodon_1 PF08264.8 CCF52151.1 - 0.00025 20.8 0.2 0.014 15.1 0.0 2.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA BSP_II PF05432.6 CCF52151.1 - 0.056 12.7 10.2 0.13 11.5 7.0 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HEAT_EZ PF13513.1 CCF52151.1 - 1.6 9.3 8.7 0.42 11.1 0.2 4.5 4 1 1 5 5 5 0 HEAT-like repeat zf-MYND PF01753.13 CCF52152.1 - 9.5e-12 44.5 12.4 9.5e-12 44.5 8.6 3.3 3 2 0 3 3 3 1 MYND finger SET PF00856.23 CCF52152.1 - 1.1e-09 38.7 0.0 3.8e-09 37.0 0.0 1.8 1 1 0 1 1 1 1 SET domain Aminotran_1_2 PF00155.16 CCF52154.1 - 3.8e-37 128.1 0.0 8e-37 127.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II CHCH PF06747.8 CCF52155.1 - 1.5e-09 37.5 3.9 2.1e-09 37.0 2.7 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCF52155.1 - 0.021 14.5 0.9 0.034 13.9 0.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CCF52155.1 - 0.043 13.8 4.1 0.38 10.8 2.8 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 CCF52155.1 - 1.4 8.9 4.5 4.4 7.3 0.6 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Actin PF00022.14 CCF52156.1 - 4.7e-35 120.7 0.0 5.8e-34 117.1 0.0 2.6 1 1 0 1 1 1 1 Actin TIP_N PF12457.3 CCF52156.1 - 0.031 14.3 3.1 0.059 13.4 2.1 1.4 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal DUF2348 PF09807.4 CCF52158.1 - 0.042 12.9 0.3 0.044 12.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) Calici_coat PF00915.15 CCF52159.1 - 0.054 12.3 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Calicivirus coat protein DUF3460 PF11943.3 CCF52160.1 - 0.23 11.5 0.9 0.52 10.4 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3460) Gln-synt_C PF00120.19 CCF52161.1 - 7.7e-53 179.2 0.3 6.9e-51 172.8 0.2 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Aldedh PF00171.17 CCF52162.1 - 2.2e-126 421.9 0.2 2.6e-126 421.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF52162.1 - 2.6e-05 23.1 0.0 0.00011 21.0 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short PF00106.20 CCF52163.1 - 1.3e-25 90.2 2.1 1.9e-25 89.7 1.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF52163.1 - 4.6e-20 72.4 0.0 5.7e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF52163.1 - 5e-08 32.8 0.5 9.1e-08 31.9 0.3 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCF52163.1 - 0.0019 17.8 0.1 0.0071 16.0 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CCF52163.1 - 0.092 11.5 0.7 0.13 11.1 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCF52164.1 - 2.4e-19 69.6 0.3 9e-19 67.7 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CCF52164.1 - 6.7e-06 25.2 0.2 9.1e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCF52164.1 - 1.7e-05 24.7 0.4 5.1e-05 23.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF52164.1 - 2.8e-05 23.1 3.2 3.9e-05 22.7 1.2 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCF52164.1 - 0.00032 20.6 0.5 0.00067 19.5 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCF52164.1 - 0.00052 19.2 0.3 0.0008 18.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCF52164.1 - 0.00055 18.9 2.8 0.0012 17.7 0.9 2.3 2 1 1 3 3 3 1 FAD binding domain ApbA PF02558.11 CCF52164.1 - 0.0068 15.8 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 CCF52164.1 - 0.052 13.9 0.5 0.14 12.6 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 CCF52164.1 - 0.063 12.9 0.0 0.74 9.5 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Trp_halogenase PF04820.9 CCF52164.1 - 0.066 11.8 0.5 0.62 8.6 0.2 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 CCF52164.1 - 0.13 10.7 0.2 0.27 9.6 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CCF52164.1 - 0.16 10.7 1.2 0.28 10.0 0.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A EthD PF07110.6 CCF52165.1 - 7.2e-18 65.3 0.2 9.1e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 EthD domain DUF4528 PF15031.1 CCF52165.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) COesterase PF00135.23 CCF52166.1 - 2.1e-92 310.6 1.3 3e-92 310.0 0.9 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF52166.1 - 1.2e-08 34.7 0.3 8e-08 32.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF52166.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52166.1 - 0.018 14.7 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_2 PF07727.9 CCF52167.1 - 1.6e-38 132.0 0.1 2.1e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Imm24 PF15570.1 CCF52167.1 - 0.12 12.1 1.5 0.21 11.3 1.0 1.3 1 0 0 1 1 1 0 Immunity protein 24 Acetyltransf_1 PF00583.19 CCF52169.1 - 1.4e-07 31.4 0.0 2.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF52169.1 - 2.8e-07 30.6 0.0 8.1e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF52169.1 - 5.5e-07 29.7 0.4 6.9e-06 26.1 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF52169.1 - 0.002 17.9 0.4 0.009 15.8 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 CCF52170.1 - 4.7e-25 88.0 75.8 1.6e-18 66.5 30.0 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily ADH_N PF08240.7 CCF52171.1 - 3.8e-21 74.8 1.9 7.1e-21 74.0 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF52171.1 - 2.1e-16 59.6 0.0 1.8e-15 56.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCF52171.1 - 2.1e-05 23.7 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCF52171.1 - 0.00013 22.0 0.0 0.00042 20.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CCF52171.1 - 0.00039 19.9 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CCF52171.1 - 0.00039 20.3 0.0 0.00087 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CCF52171.1 - 0.0062 16.1 0.4 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 CCF52171.1 - 0.0079 16.4 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding XdhC_C PF13478.1 CCF52171.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 CCF52171.1 - 0.03 14.1 0.8 0.074 12.8 0.6 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 CCF52171.1 - 0.038 13.6 0.2 0.083 12.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CCF52171.1 - 0.044 14.2 0.2 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF1308 PF07000.6 CCF52172.1 - 1.8e-19 69.6 0.0 9.2e-09 34.3 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1308) LCCL PF03815.14 CCF52172.1 - 8.8e-18 64.0 0.1 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 LCCL domain RVT_2 PF07727.9 CCF52175.1 - 6.3e-17 61.3 0.0 8.7e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lyase_8_N PF08124.6 CCF52176.1 - 1.6 7.5 6.1 1.1 8.1 0.2 2.1 2 0 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain FAD_binding_4 PF01565.18 CCF52177.1 - 1.5e-24 86.0 0.2 2.6e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCF52177.1 - 3.7e-14 52.3 0.0 7.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 CCF52177.1 - 0.13 11.3 0.2 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Asp_Glu_race PF01177.17 CCF52178.1 - 2.2e-20 73.4 0.5 2.6e-20 73.2 0.3 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.6 CCF52178.1 - 0.081 12.2 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 AroM protein Herpes_glycop PF01528.11 CCF52179.1 - 0.4 9.3 0.3 5.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus glycoprotein M WD40 PF00400.27 CCF52180.1 - 8.9e-42 139.5 30.0 3.8e-10 39.2 0.1 11.1 12 0 0 12 12 12 9 WD domain, G-beta repeat Nbas_N PF15492.1 CCF52180.1 - 0.00038 19.6 2.3 0.37 9.8 0.0 3.7 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Lgl_C PF08596.5 CCF52180.1 - 0.00039 18.9 0.3 0.0046 15.4 0.1 2.1 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal IceA2 PF05862.6 CCF52180.1 - 0.86 9.3 3.6 3.2 7.5 0.1 3.5 4 1 0 4 4 4 0 Helicobacter pylori IceA2 protein ABC_tran PF00005.22 CCF52181.1 - 9.6e-18 64.8 0.0 4e-12 46.6 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCF52181.1 - 5.1e-07 29.9 0.6 0.14 12.1 0.0 3.2 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 CCF52181.1 - 0.00019 21.2 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 CCF52181.1 - 0.0004 20.0 0.0 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 CCF52181.1 - 0.00081 18.8 0.1 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 CCF52181.1 - 0.035 13.0 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.13 CCF52181.1 - 0.045 13.2 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 CCF52181.1 - 0.051 12.9 0.1 0.42 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 CCF52181.1 - 0.094 11.9 0.1 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCF52181.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CCF52181.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 CCF52181.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 CCF52181.1 - 0.18 10.9 0.0 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCF52181.1 - 0.19 11.6 7.2 0.078 12.9 0.8 2.8 2 2 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.1 CCF52181.1 - 0.38 9.7 0.0 1.5 7.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MBOAT_2 PF13813.1 CCF52182.1 - 1.3e-05 25.1 4.4 0.0023 17.9 0.1 3.3 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family RVT_2 PF07727.9 CCF52184.1 - 6.7e-17 61.2 0.1 8.7e-17 60.9 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) La PF05383.12 CCF52184.1 - 0.036 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 La domain rve PF00665.21 CCF52185.1 - 5e-10 39.5 0.0 8.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chorion_3 PF05387.6 CCF52187.1 - 0.17 11.3 4.8 0.22 10.9 3.3 1.3 1 0 0 1 1 1 0 Chorion family 3 TPT PF03151.11 CCF52188.1 - 2.5e-35 121.3 3.5 2.5e-35 121.3 2.4 2.8 2 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CCF52188.1 - 2.7e-13 50.0 24.3 4.8e-07 29.8 7.1 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CCF52188.1 - 2.1e-11 43.2 12.6 6.6e-11 41.6 8.7 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CCF52188.1 - 0.0001 21.4 11.1 0.0025 16.9 1.1 3.0 2 1 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 CCF52188.1 - 0.0076 16.4 16.4 0.13 12.4 3.1 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Plasmod_dom_1 PF09715.5 CCF52188.1 - 0.0097 15.8 1.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 1 Plasmodium protein of unknown function (Plasmod_dom_1) Multi_Drug_Res PF00893.14 CCF52188.1 - 0.032 14.6 3.5 0.032 14.6 2.4 2.2 2 0 0 2 2 2 0 Small Multidrug Resistance protein UQ_con PF00179.21 CCF52189.1 - 6.2e-19 67.8 0.0 1.4e-18 66.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RAI1 PF08652.6 CCF52190.1 - 2.1e-18 65.8 0.0 4.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease CoA_transf_3 PF02515.12 CCF52191.1 - 2.3e-42 144.4 0.0 3.8e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III ELO PF01151.13 CCF52192.1 - 1.7e-60 204.4 18.8 2.2e-60 204.0 13.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2312 PF10073.4 CCF52193.1 - 0.04 13.2 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) zf-C2H2 PF00096.21 CCF52195.1 - 1.3e-06 28.3 6.8 0.001 19.2 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF3493 PF11998.3 CCF52195.1 - 0.0044 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) zf-H2C2_2 PF13465.1 CCF52195.1 - 0.0095 16.1 0.4 0.0095 16.1 0.2 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCF52195.1 - 0.014 15.3 0.4 0.041 13.8 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCF52195.1 - 2.4 8.6 24.0 0.19 12.1 0.3 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger adh_short PF00106.20 CCF52196.1 - 1.4e-24 86.9 0.0 2.3e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF52196.1 - 2.3e-08 34.1 0.1 5.5e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF52196.1 - 5.6e-05 22.8 2.2 0.00084 19.0 1.5 2.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCF52196.1 - 0.00032 20.7 0.1 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCF52196.1 - 0.0029 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 CCF52196.1 - 0.0032 17.2 0.1 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) YjeF_N PF03853.10 CCF52196.1 - 0.0062 16.1 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.14 CCF52196.1 - 0.0088 15.2 0.1 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DEDD_Tnp_IS110 PF01548.12 CCF52196.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Transposase 3HCDH_N PF02737.13 CCF52196.1 - 0.02 14.5 0.2 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 CCF52196.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family 3Beta_HSD PF01073.14 CCF52196.1 - 0.098 11.3 0.1 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.14 CCF52196.1 - 0.21 10.6 0.7 0.32 10.0 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain RVT_2 PF07727.9 CCF52198.1 - 2.5e-25 88.8 0.0 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF52200.1 - 1.1e-05 25.0 0.1 3.2e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF52200.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Methyltransf_11 PF08241.7 CCF52201.1 - 1.8e-16 60.3 0.0 5.1e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF52201.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52201.1 - 1.9e-06 28.3 0.0 3.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF52201.1 - 2e-06 28.1 0.0 4.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF52201.1 - 3e-06 27.6 0.0 1.4e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF52201.1 - 3.2e-06 26.8 0.0 1.5e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF52201.1 - 1e-05 25.5 0.0 2.7e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF52201.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF4210 PF13915.1 CCF52202.1 - 2.1e-21 75.9 0.0 5.4e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 CCF52202.1 - 8.7e-18 63.9 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4098 PF13345.1 CCF52204.1 - 0.022 14.7 1.7 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4098) DUF4497 PF14924.1 CCF52204.1 - 0.069 13.4 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4497) ECH PF00378.15 CCF52206.1 - 6.9e-42 143.2 1.0 1.5e-40 138.8 0.7 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pmp3 PF01679.12 CCF52207.1 - 2.3e-20 71.9 8.6 2.9e-20 71.7 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TraW_N PF12477.3 CCF52207.1 - 0.66 9.9 4.1 2.8 7.9 1.3 2.2 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal PS_Dcarbxylase PF02666.10 CCF52208.1 - 1.4e-77 259.5 0.0 4.7e-59 199.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase SBP_bac_11 PF13531.1 CCF52208.1 - 0.04 13.5 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein NADH_oxidored PF08040.6 CCF52208.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 MNLL subunit Nnf1 PF03980.9 CCF52209.1 - 1.5e-11 44.2 7.8 1.5e-11 44.2 5.4 2.3 3 0 0 3 3 3 1 Nnf1 Filament PF00038.16 CCF52209.1 - 0.001 18.6 6.4 0.001 18.6 4.4 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF2968 PF11180.3 CCF52209.1 - 0.005 16.2 11.4 0.0052 16.1 5.2 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2968) Ank_5 PF13857.1 CCF52210.1 - 2.4e-31 107.0 3.3 4.1e-10 39.5 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CCF52210.1 - 2.1e-30 103.0 0.4 6.8e-09 35.1 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CCF52210.1 - 1.5e-29 102.1 0.3 6.3e-23 80.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCF52210.1 - 3e-28 97.6 1.6 7.5e-15 54.9 0.2 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF52210.1 - 1.2e-21 74.5 0.2 4.7e-05 23.2 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 CCF52210.1 - 6e-20 70.9 6.5 6e-20 70.9 4.5 3.0 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 CCF52210.1 - 1.7e-10 40.5 3.7 1.7e-10 40.5 2.6 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF52210.1 - 0.00025 21.0 5.3 0.00025 21.0 3.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF52210.1 - 0.0094 16.0 1.7 0.0094 16.0 1.2 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger RINGv PF12906.2 CCF52210.1 - 0.055 13.5 3.8 0.21 11.6 2.6 2.0 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CCF52210.1 - 0.098 12.3 6.6 0.021 14.5 1.4 2.2 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 CCF52210.1 - 0.27 11.2 5.7 0.15 12.0 1.7 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.11 CCF52210.1 - 3.5 7.5 7.9 0.13 12.2 0.8 2.0 2 0 0 2 2 1 0 FYVE-type zinc finger PepSY_TM_2 PF13703.1 CCF52211.1 - 0.15 12.2 0.2 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Hist_deacetyl PF00850.14 CCF52212.1 - 9.6e-92 307.5 0.0 1.5e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCF52212.1 - 7.6e-22 77.5 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain DUF3530 PF12048.3 CCF52212.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PTPA PF03095.10 CCF52213.1 - 9e-111 369.8 0.0 1.2e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RGS PF00615.14 CCF52214.1 - 1.9e-37 127.9 0.0 9.2e-37 125.7 0.0 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 CCF52214.1 - 4.6e-10 39.1 0.0 0.00021 20.9 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 CCF52214.1 - 0.015 15.1 0.1 2.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix 3HCDH_N PF02737.13 CCF52215.1 - 2.6e-44 151.0 3.5 2.3e-43 147.9 2.4 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CCF52215.1 - 3.5e-34 117.0 0.0 6.8e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCF52215.1 - 0.093 12.5 1.3 1.2 8.9 0.9 2.2 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 CCF52215.1 - 0.12 11.2 0.2 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Arf PF00025.16 CCF52216.1 - 2.3e-27 95.3 0.1 2.3e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 ADP-ribosylation factor family G-alpha PF00503.15 CCF52216.1 - 1.7e-08 33.6 0.0 3.2e-06 26.0 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CCF52216.1 - 2.4e-07 30.2 0.0 2.2e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCF52216.1 - 5.6e-06 26.8 0.0 1.3e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 CCF52216.1 - 6.6e-05 22.8 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCF52216.1 - 0.0001 21.5 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CCF52216.1 - 0.012 15.7 0.0 0.034 14.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCF52216.1 - 0.017 15.0 0.1 0.037 14.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCF52216.1 - 0.038 13.1 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCF52216.1 - 0.057 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 CCF52216.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family DUF1640 PF07798.6 CCF52217.1 - 4.2e-64 215.8 3.7 5.1e-64 215.5 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) T2SK PF03934.8 CCF52217.1 - 0.0094 15.1 0.3 0.015 14.4 0.2 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein K DUF647 PF04884.9 CCF52217.1 - 0.047 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis HCaRG PF07258.9 CCF52217.1 - 0.065 12.7 1.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 HCaRG protein HALZ PF02183.13 CCF52217.1 - 0.076 12.7 2.3 0.46 10.2 1.6 2.3 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 CCF52217.1 - 0.14 12.1 1.5 3.5 7.6 0.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) NPR2 PF06218.6 CCF52217.1 - 0.15 10.7 0.2 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 FIST PF08495.5 CCF52218.1 - 0.00063 18.9 0.1 0.0026 16.9 0.0 2.0 2 0 0 2 2 2 1 FIST N domain Erv26 PF04148.8 CCF52218.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 UPF0172 PF03665.8 CCF52219.1 - 3.8e-51 173.3 0.1 4.5e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 CCF52219.1 - 0.007 16.0 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Methyltransf_6 PF03737.10 CCF52220.1 - 4.2e-22 78.6 0.3 3.1e-20 72.5 0.2 2.1 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase SAP PF02037.22 CCF52221.1 - 1.4e-10 40.4 0.7 2.3e-10 39.7 0.5 1.4 1 0 0 1 1 1 1 SAP domain Lipase_3 PF01764.20 CCF52222.1 - 4.2e-26 91.2 0.0 5.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 CCF52222.1 - 0.00037 20.2 0.9 0.027 14.1 0.0 2.2 1 1 0 2 2 2 2 Cutinase Abhydrolase_6 PF12697.2 CCF52222.1 - 0.0022 17.9 0.1 0.0038 17.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52222.1 - 0.032 13.9 0.2 0.05 13.3 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 CCF52222.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 CCF52225.1 - 2.9e-12 46.6 0.0 1.1e-11 44.7 0.0 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF52225.1 - 7.7e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF52225.1 - 7.2e-07 29.3 0.2 1.1e-06 28.7 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF52225.1 - 1.5e-05 24.3 0.1 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 CCF52225.1 - 0.0014 17.4 0.1 0.0032 16.2 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family MR_MLE_C PF13378.1 CCF52226.1 - 1.1e-11 44.6 0.0 2.8e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CCF52226.1 - 5.5e-10 39.6 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 CCF52226.1 - 0.00024 21.0 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Lipase_3 PF01764.20 CCF52227.1 - 2.2e-17 62.9 0.0 3.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) TRAP_alpha PF03896.11 CCF52227.1 - 0.83 8.5 1.5 1.5 7.7 1.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GST_N_3 PF13417.1 CCF52229.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF52229.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCF52229.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain G_glu_transpept PF01019.16 CCF52231.1 - 8.6e-135 450.0 1.9 3.7e-133 444.7 1.3 2.0 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.20 CCF52233.1 - 4.4e-70 235.7 0.0 6.3e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52233.1 - 1.5e-32 112.6 0.0 4.2e-31 107.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF52233.1 - 4.3e-05 22.6 2.5 0.73 8.7 0.0 3.6 3 1 1 4 4 4 2 Kinase-like RIO1 PF01163.17 CCF52233.1 - 5.3e-05 22.6 1.9 9.5e-05 21.8 1.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CCF52233.1 - 0.0048 16.6 7.2 0.094 12.4 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CCF52233.1 - 0.041 12.6 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TFIIA PF03153.8 CCF52233.1 - 7.7 6.3 23.1 8.2 6.2 2.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G10 PF01125.12 CCF52234.1 - 8.5e-64 213.4 3.7 9.6e-64 213.3 2.6 1.0 1 0 0 1 1 1 1 G10 protein DEAD PF00270.24 CCF52235.1 - 8.2e-23 80.7 0.0 1.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CCF52235.1 - 5.2e-13 49.3 0.2 2e-12 47.4 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CCF52235.1 - 2.7e-12 46.3 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCF52235.1 - 2.5e-06 27.5 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like T2SE PF00437.15 CCF52235.1 - 0.079 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_31 PF13847.1 CCF52236.1 - 2e-18 66.4 0.0 2.6e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF52236.1 - 1.9e-15 56.9 0.0 2.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF52236.1 - 5.1e-13 49.3 0.0 8.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF52236.1 - 1.1e-12 48.2 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52236.1 - 2.7e-11 44.0 0.0 4.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF52236.1 - 5.5e-08 32.2 0.0 4.3e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCF52236.1 - 7e-08 32.2 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 CCF52236.1 - 2.6e-07 30.9 0.0 3.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF52236.1 - 1.4e-05 24.5 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCF52236.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCF52236.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.15 CCF52236.1 - 0.062 12.3 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CCF52236.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CCF52236.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CCF52236.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Pyridoxal_deC PF00282.14 CCF52237.1 - 3e-64 216.8 0.0 4e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CCF52237.1 - 0.0094 14.7 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCF52237.1 - 0.012 14.7 0.0 0.038 13.1 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DUF155 PF02582.9 CCF52238.1 - 4.9e-53 179.6 0.1 7.8e-53 178.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Rhomboid PF01694.17 CCF52239.1 - 2.3e-22 79.5 7.7 2.3e-22 79.5 5.3 1.7 2 0 0 2 2 2 1 Rhomboid family PIG-P PF08510.7 CCF52239.1 - 1.9 8.1 5.7 4.9 6.8 3.9 1.7 1 1 0 1 1 1 0 PIG-P Thioredoxin PF00085.15 CCF52240.1 - 0.0022 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SPX PF03105.14 CCF52240.1 - 0.01 15.6 4.1 0.014 15.2 2.9 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.4 CCF52240.1 - 1 7.5 4.7 1.3 7.2 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Inhibitor_I9 PF05922.11 CCF52241.1 - 1.2e-07 32.2 0.1 3.1e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 UPF0029 PF01205.14 CCF52242.1 - 2.9e-28 97.7 0.0 5.2e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCF52242.1 - 6.3e-07 29.2 0.1 2.3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 RWD domain F-box-like PF12937.2 CCF52243.1 - 0.022 14.4 0.4 0.063 13.0 0.3 1.9 1 0 0 1 1 1 0 F-box-like Peptidase_M50B PF13398.1 CCF52244.1 - 1.7e-57 194.0 15.9 2.2e-57 193.7 11.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Wzy_C PF04932.10 CCF52244.1 - 2.2 8.0 11.1 0.65 9.7 4.6 2.1 2 1 0 2 2 2 0 O-Antigen ligase O-antigen_lig PF13425.1 CCF52244.1 - 9.8 6.1 16.2 41 4.1 8.9 2.6 2 1 0 2 2 2 0 O-antigen ligase like membrane protein His_Phos_1 PF00300.17 CCF52245.1 - 4e-27 95.2 0.3 1.3e-26 93.5 0.1 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Lactonase PF10282.4 CCF52252.1 - 1.2e-17 64.0 0.0 5.7e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 CCF52252.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region VirionAssem_T7 PF11653.3 CCF52252.1 - 0.05 14.3 0.3 0.098 13.4 0.2 1.4 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein FAD_binding_4 PF01565.18 CCF52253.1 - 4.8e-21 74.6 3.1 8.1e-21 73.9 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCF52253.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.19 CCF52254.1 - 1.1e-08 34.9 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCF52254.1 - 4e-05 23.7 0.0 9.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCF52254.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_26 PF13659.1 CCF52255.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCF52255.1 - 3.5e-09 36.4 0.2 5.8e-08 32.5 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 CCF52255.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase AA_permease_2 PF13520.1 CCF52256.1 - 5.8e-65 219.4 54.3 7.1e-65 219.1 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF52256.1 - 1.7e-06 26.6 50.1 6.5e-06 24.7 34.7 1.7 1 1 0 1 1 1 1 Amino acid permease DUF3377 PF11857.3 CCF52256.1 - 0.31 10.7 1.2 0.88 9.2 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pyr_redox_3 PF13738.1 CCF52257.1 - 3.4e-24 86.0 0.0 4.4e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCF52257.1 - 7.8e-18 63.9 0.1 4.8e-17 61.3 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 CCF52257.1 - 6.8e-16 58.7 0.1 5.3e-10 39.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF52257.1 - 4.5e-11 42.2 1.0 1e-08 34.5 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF52257.1 - 2.7e-10 40.1 2.2 2.7e-08 33.6 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCF52257.1 - 2e-07 31.3 2.4 0.0053 17.1 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF52257.1 - 7.1e-07 29.1 8.6 4.3e-05 23.3 0.7 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 CCF52257.1 - 3.3e-06 26.2 0.1 0.0016 17.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 CCF52257.1 - 7.8e-05 22.7 0.1 0.52 10.4 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCF52257.1 - 0.00013 22.1 0.0 0.17 12.1 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding 3HCDH_N PF02737.13 CCF52257.1 - 0.00036 20.2 0.3 0.00036 20.2 0.2 1.8 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CCF52257.1 - 0.0004 19.5 2.6 0.046 12.7 0.4 2.6 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 CCF52257.1 - 0.0012 17.9 0.0 0.0035 16.4 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 CCF52257.1 - 0.0027 17.2 1.4 0.82 9.2 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 CCF52257.1 - 0.0056 15.5 0.4 0.0056 15.5 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCF52257.1 - 0.0057 15.7 1.5 0.17 10.9 0.2 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CCF52257.1 - 0.007 14.8 4.5 0.065 11.6 0.6 2.4 2 0 0 2 2 2 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 CCF52257.1 - 0.047 13.0 0.5 0.081 12.2 0.4 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CCF52257.1 - 0.055 12.6 0.2 6.3 5.9 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 CCF52257.1 - 0.059 12.2 2.6 1 8.1 0.2 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_2 PF03446.10 CCF52257.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CCF52257.1 - 0.41 10.6 2.6 2.8 7.8 0.2 2.3 2 0 0 2 2 2 0 NADH(P)-binding ThiF PF00899.16 CCF52257.1 - 0.44 10.3 2.8 8.5 6.2 0.2 2.4 2 0 0 2 2 2 0 ThiF family ADH_N PF08240.7 CCF52258.1 - 9.9e-26 89.6 3.1 2.1e-25 88.6 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF52258.1 - 1e-23 83.3 0.0 1.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF52258.1 - 0.017 15.9 0.0 0.041 14.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.2 CCF52261.1 - 1.3e-09 37.6 1.7 2.8e-09 36.5 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF52261.1 - 2.7e-08 33.2 0.8 1.1e-07 31.3 0.3 2.3 2 0 0 2 2 2 1 F-box domain TPR_11 PF13414.1 CCF52261.1 - 0.00045 19.8 5.6 0.0022 17.5 0.7 2.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCF52261.1 - 0.00049 19.8 3.2 0.038 13.9 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCF52261.1 - 0.00094 18.9 0.1 0.0028 17.4 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCF52261.1 - 0.0037 16.8 0.4 0.1 12.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCF52261.1 - 0.03 13.3 1.3 0.071 12.1 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCF52261.1 - 0.039 14.6 7.0 0.056 14.1 1.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52261.1 - 0.046 14.3 6.3 0.61 10.8 0.2 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52261.1 - 0.11 12.4 2.3 0.52 10.2 1.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCF52262.1 - 0.0014 18.8 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF52262.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 CCF52262.1 - 0.012 15.5 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Transpep_BrtH PF14399.1 CCF52262.1 - 0.026 13.8 0.0 0.031 13.5 0.0 1.1 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase TPR_17 PF13431.1 CCF52262.1 - 0.047 13.9 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.22 CCF52263.1 - 2e-43 148.0 0.7 1.2e-22 80.7 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CCF52263.1 - 5.3e-15 56.1 3.8 6e-05 23.1 0.2 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 CCF52263.1 - 8.5e-11 41.5 0.0 0.00067 18.9 0.0 3.7 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF52263.1 - 3.2e-09 36.1 0.4 0.0021 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_2 PF12848.2 CCF52263.1 - 1.8e-07 30.8 4.8 5.4e-07 29.3 3.3 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 CCF52263.1 - 1.6e-06 28.6 7.1 0.0035 17.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCF52263.1 - 5.8e-06 26.4 0.1 0.026 14.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCF52263.1 - 5.9e-06 26.2 0.1 0.023 14.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 CCF52263.1 - 6.7e-06 25.6 0.3 0.16 11.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CCF52263.1 - 1.1e-05 26.2 0.5 0.11 13.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCF52263.1 - 3.9e-05 22.9 0.6 0.26 10.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCF52263.1 - 8.7e-05 22.5 4.8 0.058 13.3 0.0 3.4 3 2 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 CCF52263.1 - 0.0001 22.5 0.7 0.4 10.8 0.2 3.5 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 CCF52263.1 - 0.00015 20.6 2.0 0.54 8.9 0.1 3.4 3 0 0 3 3 3 2 ArgK protein NACHT PF05729.7 CCF52263.1 - 0.00015 21.4 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 CCF52263.1 - 0.00016 20.8 0.1 1.2 8.1 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain MobB PF03205.9 CCF52263.1 - 0.00041 20.0 1.5 0.081 12.6 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCF52263.1 - 0.00061 18.7 0.2 0.36 9.6 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain Miro PF08477.8 CCF52263.1 - 0.0011 19.3 0.0 0.58 10.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 CCF52263.1 - 0.0014 18.5 0.3 4.3 7.2 0.0 3.5 5 0 0 5 5 2 0 AAA domain SbcCD_C PF13558.1 CCF52263.1 - 0.0016 18.3 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCF52263.1 - 0.0016 18.5 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 CCF52263.1 - 0.0038 16.9 0.4 7.7 6.2 0.0 3.7 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCF52263.1 - 0.0058 16.5 1.8 2.7 7.8 0.0 3.5 3 1 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 CCF52263.1 - 0.013 15.2 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 CCF52263.1 - 0.021 14.5 3.7 0.82 9.3 0.1 3.1 3 0 0 3 3 3 0 NTPase GTP_EFTU PF00009.22 CCF52263.1 - 0.021 14.2 0.5 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 CCF52263.1 - 0.029 14.3 2.0 4.4 7.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 CCF52263.1 - 0.067 12.6 0.6 9.2 5.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 CCF52263.1 - 0.072 12.7 4.0 1.4 8.5 0.0 3.1 4 0 0 4 4 3 0 Archaeal ATPase AAA_18 PF13238.1 CCF52263.1 - 0.077 13.2 0.6 4.7 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mucin PF01456.12 CCF52263.1 - 0.13 12.0 11.8 0.24 11.1 8.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC_ATPase PF09818.4 CCF52263.1 - 0.15 10.5 6.9 0.18 10.3 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.12 CCF52263.1 - 0.16 11.3 4.0 4.7 6.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 CCF52263.1 - 0.21 11.0 5.8 0.84 9.0 0.2 3.1 4 0 0 4 4 3 0 AAA-like domain Ribosomal_60s PF00428.14 CCF52263.1 - 0.28 11.5 10.9 0.81 10.1 0.5 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein cobW PF02492.14 CCF52263.1 - 0.86 9.0 4.0 3.3 7.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 CCF52263.1 - 7.8 6.2 9.8 1.5 8.6 0.1 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 4HBT PF03061.17 CCF52264.1 - 2.6e-16 59.4 4.4 8e-09 35.5 0.1 2.6 2 0 0 2 2 2 2 Thioesterase superfamily AA_permease_2 PF13520.1 CCF52265.1 - 1.5e-56 191.8 56.7 1.9e-56 191.4 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF52265.1 - 2.5e-31 108.5 48.2 3.4e-31 108.1 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease MMgT PF10270.4 CCF52266.1 - 7.6e-24 84.1 0.1 8.7e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter TcpE PF12648.2 CCF52266.1 - 0.1 12.7 0.4 0.17 12.0 0.2 1.4 1 1 0 1 1 1 0 TcpE family Sedlin_N PF04628.8 CCF52267.1 - 7.4e-36 122.9 0.0 8.7e-36 122.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_M20 PF01546.23 CCF52268.1 - 2.4e-32 111.9 0.0 4.4e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCF52268.1 - 3.5e-12 46.0 0.0 7.6e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain Aa_trans PF01490.13 CCF52269.1 - 5.4e-64 216.1 8.7 6.4e-64 215.9 6.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCF52269.1 - 2e-05 23.6 6.6 2e-05 23.6 4.6 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2107 PF09880.4 CCF52269.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) zf-C3HC4_2 PF13923.1 CCF52270.1 - 2.5e-07 30.5 5.6 2.5e-07 30.5 3.9 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52270.1 - 2.7e-07 30.2 5.6 2.7e-07 30.2 3.9 3.3 2 1 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.13 CCF52270.1 - 2.9e-07 30.7 33.7 9e-07 29.1 2.2 5.0 3 1 1 5 5 5 3 TRAF-type zinc finger zf-RING_2 PF13639.1 CCF52270.1 - 3.4e-07 29.9 7.4 3.4e-07 29.9 5.2 3.7 3 1 0 3 3 3 1 Ring finger domain zf-Nse PF11789.3 CCF52270.1 - 1.3e-06 27.8 3.2 2.7e-05 23.6 2.4 2.5 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 CCF52270.1 - 6.7e-06 25.6 6.3 6.7e-06 25.6 4.3 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF52270.1 - 7.5e-05 22.3 2.6 0.00023 20.8 1.8 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCF52270.1 - 0.0026 17.6 7.3 0.0026 17.6 5.1 2.9 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CCF52270.1 - 0.015 15.0 2.0 0.14 11.9 0.3 2.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein C2 PF00168.25 CCF52271.1 - 1.6e-17 63.1 0.0 1.6e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF4131 PF13567.1 CCF52271.1 - 0.1 11.9 1.1 3.2 7.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_3 PF13302.1 CCF52272.1 - 4e-16 59.4 0.0 5.7e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF52272.1 - 0.00056 19.8 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF52272.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MoCo_carrier PF12694.2 CCF52272.1 - 0.047 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative molybdenum carrier RNaseH_C PF09293.5 CCF52272.1 - 0.061 13.2 0.0 1.2 9.1 0.1 2.2 1 1 1 2 2 2 0 T4 RNase H, C terminal Pyr_redox_2 PF07992.9 CCF52274.1 - 3.2e-24 85.9 0.0 2e-15 57.2 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF52274.1 - 8.5e-13 48.5 0.0 8.3e-12 45.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF52274.1 - 0.00035 20.6 0.2 0.035 14.1 0.0 3.5 3 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCF52274.1 - 0.059 13.6 0.1 2.3 8.5 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding RCC1 PF00415.13 CCF52275.1 - 7.5e-18 64.4 8.8 0.0046 17.1 0.0 7.2 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCF52275.1 - 4.2e-09 35.7 17.2 0.05 13.2 0.0 6.8 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_6 PF12697.2 CCF52277.1 - 0.024 14.5 0.1 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52277.1 - 0.072 12.8 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 CCF52278.1 - 1.3e-39 135.9 0.0 3.7e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52278.1 - 4.3e-15 55.4 0.0 1.6e-10 40.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF52278.1 - 4.3e-05 22.6 0.0 0.052 12.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCF52278.1 - 0.049 13.3 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family MIP PF00230.15 CCF52279.1 - 8.4e-26 90.8 10.3 1.2e-25 90.3 7.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Rubis-subs-bind PF09273.6 CCF52280.1 - 0.00011 22.1 0.0 0.0026 17.6 0.0 2.5 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding RTA1 PF04479.8 CCF52281.1 - 2.7e-50 170.9 0.6 4.3e-50 170.2 0.4 1.3 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.1 CCF52281.1 - 0.079 12.6 4.4 0.052 13.2 0.5 2.1 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Tox-SGS PF15651.1 CCF52281.1 - 0.2 11.4 0.9 11 5.8 0.0 2.6 2 1 0 2 2 2 0 Salivary glad secreted protein domain toxin Epimerase PF01370.16 CCF52283.1 - 1.3e-20 73.8 0.0 2.2e-20 73.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCF52283.1 - 8.8e-10 37.7 0.0 2.4e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCF52283.1 - 1.8e-08 33.6 0.0 1.5e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CCF52283.1 - 1.3e-06 27.5 0.0 0.00014 20.8 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 CCF52283.1 - 1.8e-05 24.8 0.0 8.9e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCF52283.1 - 0.007 16.3 0.0 0.1 12.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CCF52283.1 - 0.0088 15.3 0.0 2.6 7.2 0.0 2.8 2 2 1 3 3 3 2 NmrA-like family Saccharop_dh PF03435.13 CCF52283.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3222 PF11519.3 CCF52283.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) Hexokinase_2 PF03727.11 CCF52284.1 - 3.6e-72 242.4 0.3 4.8e-72 242.0 0.2 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCF52284.1 - 5e-66 221.9 0.0 7.5e-66 221.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase His_Phos_2 PF00328.17 CCF52285.1 - 4.7e-30 105.1 0.0 5.8e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Complex1_LYR PF05347.10 CCF52286.1 - 3.3e-13 49.2 0.1 2.1e-12 46.6 0.1 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCF52286.1 - 1.3e-10 41.3 0.1 6.8e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCF52286.1 - 1.7e-06 28.4 0.9 7.6e-06 26.3 0.1 2.0 1 1 1 2 2 2 1 Complex1_LYR-like DUF543 PF04418.7 CCF52288.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF543) PseudoU_synth_2 PF00849.17 CCF52289.1 - 1.3e-23 83.6 0.0 2.8e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0020 PF01170.13 CCF52289.1 - 8.7e-15 54.7 0.0 2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCF52289.1 - 6.5e-13 48.7 0.0 2.1e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF52289.1 - 4.4e-07 29.5 0.0 9.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52289.1 - 0.033 14.7 0.0 0.07 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 CCF52290.1 - 3.9e-57 193.8 7.6 7.8e-57 192.9 5.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF52290.1 - 2.1e-08 34.3 5.1 3.8e-07 30.1 3.4 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCF52290.1 - 3.1e-05 24.3 1.6 0.0017 18.7 0.0 2.9 3 0 0 3 3 3 1 Aspartyl protease DUF2985 PF11204.3 CCF52292.1 - 1.6e-27 95.0 0.9 2.9e-27 94.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.1 CCF52292.1 - 0.36 10.4 5.7 0.19 11.2 1.0 2.4 2 0 0 2 2 2 0 Putative sensor Cofilin_ADF PF00241.15 CCF52293.1 - 6.9e-15 55.0 0.0 5.7e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein adh_short_C2 PF13561.1 CCF52294.1 - 1.5e-19 70.6 0.0 2.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCF52294.1 - 1.9e-19 70.1 0.4 3.8e-19 69.2 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF52294.1 - 0.00029 20.5 0.1 0.00048 19.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 CCF52294.1 - 0.004 17.2 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 CCF52294.1 - 0.052 12.6 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AA_kinase PF00696.23 CCF52294.1 - 0.083 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family Saccharop_dh PF03435.13 CCF52294.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Complex1_LYR PF05347.10 CCF52295.1 - 7.8e-09 35.2 0.1 1.6e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCF52295.1 - 1.5e-07 31.5 0.1 2.7e-07 30.7 0.0 1.5 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCF52295.1 - 0.0072 16.7 0.4 0.0097 16.3 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Prefoldin PF02996.12 CCF52296.1 - 2e-11 43.6 0.3 2e-11 43.6 0.2 1.4 2 0 0 2 2 2 1 Prefoldin subunit FliD_N PF02465.13 CCF52296.1 - 0.048 14.0 0.5 0.43 10.9 0.0 2.3 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TFIID_90kDa PF04494.10 CCF52296.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit Trp_syntA PF00290.15 CCF52296.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DnaJ_CXXCXGXG PF00684.14 CCF52298.1 - 0.077 13.0 5.5 0.4 10.7 0.9 2.4 2 0 0 2 2 2 0 DnaJ central domain Pro_isomerase PF00160.16 CCF52299.1 - 4.5e-42 143.8 0.0 5.2e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribonuclease_3 PF00636.21 CCF52301.1 - 5e-15 55.9 0.0 2.4e-14 53.7 0.0 2.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCF52301.1 - 0.057 13.3 0.1 0.54 10.2 0.1 2.3 1 1 0 1 1 1 0 Ribonuclease-III-like NAD_binding_2 PF03446.10 CCF52302.1 - 3e-32 111.7 0.4 4.4e-32 111.1 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCF52302.1 - 7.1e-31 106.8 0.0 1.2e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CCF52302.1 - 0.056 13.8 0.2 0.21 12.0 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mcm10 PF09332.6 CCF52303.1 - 0.42 9.9 7.3 0.6 9.4 5.0 1.3 1 0 0 1 1 1 0 Mcm10 replication factor bZIP_1 PF00170.16 CCF52304.1 - 7.7e-10 38.5 10.7 5.3e-07 29.5 3.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 CCF52304.1 - 5.5e-08 32.3 3.7 1.8e-07 30.7 2.5 2.0 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 CCF52304.1 - 5.9 6.7 17.7 0.13 12.0 2.1 3.3 3 0 0 3 3 3 0 Basic region leucine zipper RVT_2 PF07727.9 CCF52306.1 - 5.9e-30 104.0 0.0 8.4e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1805 PF08827.6 CCF52307.1 - 0.25 11.1 1.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) rve PF00665.21 CCF52308.1 - 9.9e-10 38.5 0.3 2.2e-09 37.4 0.1 1.7 2 0 0 2 2 2 1 Integrase core domain RVP PF00077.15 CCF52308.1 - 0.0052 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF4106 PF13388.1 CCF52309.1 - 0.027 13.4 0.3 0.03 13.3 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Nop14 PF04147.7 CCF52310.1 - 0.0032 15.4 0.3 0.0036 15.3 0.2 1.0 1 0 0 1 1 1 1 Nop14-like family SPT6_acidic PF14632.1 CCF52310.1 - 0.0086 16.2 0.4 0.0086 16.2 0.3 2.0 3 0 0 3 3 3 1 Acidic N-terminal SPT6 Acetyltransf_1 PF00583.19 CCF52311.1 - 1.8e-09 37.4 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CCF52311.1 - 3.2e-09 37.0 0.0 5.4e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF52311.1 - 0.00018 21.4 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF52311.1 - 0.00021 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCF52311.1 - 0.0038 17.3 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCF52311.1 - 0.012 15.1 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCF52311.1 - 0.047 13.5 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 CCF52311.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Chromate_transp PF02417.10 CCF52313.1 - 9.2e-52 175.0 31.5 9.5e-27 93.6 5.6 2.8 3 1 0 3 3 3 2 Chromate transporter Sigma70_ner PF04546.8 CCF52314.1 - 0.017 14.7 7.8 0.049 13.2 5.6 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4407 PF14362.1 CCF52314.1 - 0.057 12.3 7.6 0.08 11.8 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 CCF52314.1 - 0.66 8.8 10.7 0.95 8.3 7.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SR-25 PF10500.4 CCF52314.1 - 0.96 8.8 26.3 0.18 11.2 15.3 2.0 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 CCF52314.1 - 8.7 6.1 10.5 18 5.1 7.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 CCF52314.1 - 9.8 4.7 15.1 15 4.2 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-HIT PF04438.11 CCF52315.1 - 2.6e-05 23.7 9.9 4e-05 23.1 6.8 1.3 1 0 0 1 1 1 1 HIT zinc finger Caps_assemb_Wzi PF14052.1 CCF52315.1 - 0.54 9.0 2.7 0.7 8.6 1.9 1.0 1 0 0 1 1 1 0 Capsule assembly protein Wzi Cript PF10235.4 CCF52315.1 - 1.1 9.6 5.6 0.57 10.5 2.2 2.0 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT zf-MYND PF01753.13 CCF52315.1 - 3.7 7.5 11.3 6.8 6.6 7.9 1.5 1 0 0 1 1 1 0 MYND finger Med21 PF11221.3 CCF52315.1 - 6.9 6.6 7.8 18 5.2 2.8 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Abhydrolase_6 PF12697.2 CCF52316.1 - 1e-12 48.4 0.0 1.8e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52316.1 - 0.0019 17.9 0.0 0.0069 16.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF52316.1 - 0.0041 16.7 0.0 0.22 11.0 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PDZ_2 PF13180.1 CCF52317.1 - 1.6e-05 24.6 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CCF52317.1 - 2.8e-05 24.2 0.0 6.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 CCF52317.1 - 0.00016 21.6 0.0 0.00037 20.4 0.0 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain Na_H_Exchanger PF00999.16 CCF52318.1 - 1.5e-39 135.6 16.5 2e-39 135.2 11.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hid1 PF12722.2 CCF52318.1 - 3.5 5.2 4.2 5.2 4.6 2.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_42 PF02449.10 CCF52319.1 - 6e-115 384.3 3.3 7.8e-115 383.9 2.3 1.1 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.5 CCF52319.1 - 1.3e-32 112.7 0.0 2e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain Glyco_hydro_42C PF08533.5 CCF52319.1 - 0.00051 19.4 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain Glyco_hydro_35 PF01301.14 CCF52319.1 - 0.0087 15.4 1.4 0.03 13.6 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 Methyltransf_23 PF13489.1 CCF52320.1 - 1.1e-08 34.9 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF52320.1 - 1.8e-08 34.7 0.0 4.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF52320.1 - 2e-07 31.4 0.0 6.6e-07 29.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52320.1 - 2.4e-07 31.3 0.0 5.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF52320.1 - 0.001 19.0 0.1 0.0043 17.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF52320.1 - 0.0017 17.9 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain EH_Signature PF15611.1 CCF52320.1 - 0.0029 16.7 0.0 0.019 14.0 0.1 2.2 2 1 1 3 3 3 1 EH_Signature domain Methyltransf_28 PF02636.12 CCF52320.1 - 0.008 15.6 0.0 0.014 14.7 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.1 CCF52320.1 - 0.087 13.6 0.0 0.24 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain YlbE PF14003.1 CCF52320.1 - 0.097 12.7 0.2 0.45 10.6 0.1 1.9 2 0 0 2 2 2 0 YlbE-like protein DUF3720 PF12517.3 CCF52321.1 - 0.23 12.1 1.7 0.29 11.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Pox_MCEL PF03291.11 CCF52322.1 - 9.2e-74 248.2 0.0 1.3e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 CCF52322.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF52322.1 - 2.5e-07 31.1 0.0 5.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF52322.1 - 3.9e-07 29.9 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF52322.1 - 5.8e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52322.1 - 9.5e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF52322.1 - 0.00075 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCF52322.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CTP_transf_2 PF01467.21 CCF52323.1 - 1e-29 103.5 0.0 1.6e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase tRNA-synt_1 PF00133.17 CCF52324.1 - 5.2e-159 530.0 0.0 7.4e-159 529.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCF52324.1 - 9e-31 106.7 0.0 1.8e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCF52324.1 - 4.5e-24 84.8 0.1 1.9e-13 49.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCF52324.1 - 0.00077 18.7 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 CCF52324.1 - 0.075 12.1 0.0 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Zn_clus PF00172.13 CCF52325.1 - 1.6e-05 24.6 7.1 3.2e-05 23.7 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF4G PF02854.14 CCF52326.1 - 4.6e-29 101.3 2.8 2.8e-28 98.7 0.0 2.5 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CCF52326.1 - 7.3e-27 93.3 0.1 1.5e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 MA3 domain COX6B PF02297.12 CCF52327.1 - 2.3e-26 91.5 4.5 4.5e-26 90.6 3.2 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CCF52327.1 - 0.19 11.8 2.5 5.5 7.1 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Abhydrolase_5 PF12695.2 CCF52328.1 - 4.7e-11 42.6 0.0 9.3e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF52328.1 - 1.6e-10 41.2 1.0 2.6e-10 40.5 0.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 CCF52328.1 - 1.4e-05 23.8 0.0 3.5e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.15 CCF52328.1 - 0.00025 20.6 0.3 0.3 10.5 0.0 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CCF52328.1 - 0.0081 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) zf-Tim10_DDP PF02953.10 CCF52329.1 - 5.2e-21 73.6 0.6 6.2e-21 73.4 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Sugar_tr PF00083.19 CCF52330.1 - 3.1e-113 378.7 22.1 3.6e-113 378.5 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF52330.1 - 4.6e-17 61.7 39.5 9.9e-14 50.8 11.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 CCF52330.1 - 0.00045 19.0 0.1 0.00045 19.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 CCF52330.1 - 0.068 11.3 7.7 0.01 14.0 2.2 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.4 CCF52330.1 - 1.2 9.2 6.7 0.24 11.4 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-C2H2 PF00096.21 CCF52331.1 - 2.2e-07 30.8 10.3 0.00074 19.7 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF52331.1 - 1.5e-05 25.0 3.8 1.5e-05 25.0 2.7 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCF52331.1 - 1.8e-05 24.7 9.4 0.015 15.6 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCF52331.1 - 0.36 10.7 2.2 0.49 10.3 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger TIM-br_sig_trns PF09370.5 CCF52332.1 - 2.8e-128 426.6 0.3 3.2e-128 426.4 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 CCF52332.1 - 0.0035 16.5 0.2 0.0054 15.9 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase UPF0261 PF06792.6 CCF52333.1 - 8.1e-115 383.5 0.0 1.1e-114 383.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Ste5_C PF12194.3 CCF52334.1 - 0.081 12.5 0.1 0.097 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein kinase Fus3-binding RVT_2 PF07727.9 CCF52335.1 - 7.9e-22 77.4 0.0 1.1e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YwqJ-deaminase PF14431.1 CCF52335.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase rve PF00665.21 CCF52336.1 - 2.1e-16 60.1 0.1 3.7e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCF52336.1 - 0.00093 18.7 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CCF52336.1 - 0.0011 18.4 0.0 0.0031 16.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PPR_2 PF13041.1 CCF52337.1 - 0.00045 20.1 0.4 0.037 13.9 0.0 3.9 5 0 0 5 5 5 1 PPR repeat family DUF494 PF04361.8 CCF52337.1 - 0.017 14.8 1.3 0.85 9.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF494) PPR_3 PF13812.1 CCF52337.1 - 0.04 14.1 1.5 3 8.3 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Asp PF00026.18 CCF52338.1 - 4.5e-68 229.8 5.5 7.3e-68 229.1 3.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF52338.1 - 3.3e-08 33.6 0.7 3.3e-08 33.6 0.5 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal tRNA-synt_1g PF09334.6 CCF52339.1 - 2.5e-104 349.0 0.2 6.5e-93 311.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCF52339.1 - 1.2e-20 73.1 0.0 3.8e-10 38.4 0.0 2.3 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCF52339.1 - 3.5e-10 39.5 0.1 9.5e-06 24.9 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Toxin_54 PF15533.1 CCF52340.1 - 0.0068 16.6 0.0 0.36 11.1 0.0 2.2 2 0 0 2 2 2 2 Putative toxin 54 Proteasome PF00227.21 CCF52341.1 - 7.8e-58 194.9 0.3 1e-57 194.5 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCF52341.1 - 3.2e-15 55.1 0.3 6.9e-15 54.0 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cohesin PF00963.13 CCF52341.1 - 0.22 11.3 2.0 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 Cohesin domain Ras PF00071.17 CCF52342.1 - 1e-45 155.0 0.0 1.2e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF52342.1 - 8.6e-19 68.1 0.0 3e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCF52342.1 - 5.4e-07 29.0 0.0 6.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF52342.1 - 4.1e-05 23.0 0.0 9.6e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF52342.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CCF52342.1 - 0.023 14.0 0.1 0.39 10.0 0.0 2.5 1 1 1 3 3 3 0 AAA domain SRPRB PF09439.5 CCF52342.1 - 0.035 13.3 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCF52342.1 - 0.046 13.8 1.1 0.65 10.1 0.7 2.9 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CCF52343.1 - 0.26 11.1 4.5 0.56 10.0 3.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PXA PF02194.10 CCF52343.1 - 0.32 10.5 1.7 0.88 9.1 0.4 2.2 2 0 0 2 2 2 0 PXA domain TP53IP5 PF15331.1 CCF52343.1 - 5.9 6.7 10.7 0.26 11.1 3.4 1.6 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Apt1 PF10351.4 CCF52345.1 - 2.1e-118 396.0 0.1 2.1e-118 396.0 0.1 2.9 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 CCF52345.1 - 1e-100 337.4 0.0 1e-100 337.4 0.0 1.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 CCF52345.1 - 3e-46 157.2 0.0 5.5e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCF52345.1 - 1.6e-36 125.4 0.0 3.4e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCF52345.1 - 1.6e-22 79.9 0.0 5.1e-22 78.2 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Prefoldin_2 PF01920.15 CCF52346.1 - 0.002 17.8 0.8 0.0026 17.4 0.2 1.5 2 0 0 2 2 2 1 Prefoldin subunit TauD PF02668.11 CCF52347.1 - 3.6e-36 125.1 0.1 2.2e-35 122.5 0.1 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 CCF52347.1 - 0.00014 22.2 0.0 0.0005 20.4 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 CCF52347.1 - 0.026 13.4 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 CsiD MACPF PF01823.14 CCF52347.1 - 0.041 13.5 6.2 0.71 9.5 0.6 2.2 2 0 0 2 2 2 0 MAC/Perforin domain Peptidase_M75 PF09375.5 CCF52347.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Imelysin DUF2454 PF10521.4 CCF52348.1 - 0.086 11.8 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) DUF3245 PF11595.3 CCF52348.1 - 0.35 11.1 4.0 1.4 9.2 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) PAS PF00989.19 CCF52349.1 - 1.1e-12 47.6 0.0 1.1e-10 41.3 0.0 2.9 2 1 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CCF52349.1 - 2.7e-11 43.7 0.0 8.1e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 CCF52349.1 - 1.3e-09 38.0 0.0 6e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.6 CCF52349.1 - 5.3e-07 29.6 0.0 1.4e-05 25.1 0.0 2.5 1 1 1 2 2 2 1 PAS fold PAS_8 PF13188.1 CCF52349.1 - 0.011 15.6 0.0 0.042 13.7 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_11 PF14598.1 CCF52349.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain RasGAP_C PF03836.10 CCF52350.1 - 0.57 9.8 5.8 3.4 7.3 0.2 2.9 3 1 0 3 3 3 0 RasGAP C-terminus STAG PF08514.6 CCF52351.1 - 7.9e-27 93.3 1.7 7.9e-27 93.3 1.2 3.9 4 1 1 5 5 5 1 STAG domain HEAT PF02985.17 CCF52351.1 - 0.0085 16.0 0.4 13 6.2 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Nop14 PF04147.7 CCF52351.1 - 0.2 9.5 32.0 0.27 9.1 5.8 2.6 2 0 0 2 2 2 0 Nop14-like family Sporozoite_P67 PF05642.6 CCF52351.1 - 1.4 6.6 25.4 0.13 10.1 4.3 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen zf-DHHC PF01529.15 CCF52352.1 - 2.6e-21 75.7 0.0 4.4e-21 75.0 0.0 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Suf PF05843.9 CCF52353.1 - 4.2e-89 299.0 4.9 4e-84 282.6 0.0 4.4 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CCF52353.1 - 3.2e-06 27.2 1.3 8.1 7.3 0.0 7.3 3 2 3 6 6 6 2 Tetratricopeptide repeat OmpH PF03938.9 CCF52353.1 - 4.3 7.2 15.6 0.028 14.3 4.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rad52_Rad22 PF04098.10 CCF52354.1 - 0.02 14.6 0.3 0.02 14.6 0.2 1.9 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein zf-C2H2_jaz PF12171.3 CCF52354.1 - 0.16 12.1 0.4 0.29 11.3 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RGS-like PF09128.6 CCF52354.1 - 0.24 10.8 7.5 0.47 9.9 5.2 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain TPR_11 PF13414.1 CCF52355.1 - 1.2e-52 175.4 26.8 6.1e-16 57.8 0.0 6.3 5 1 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 CCF52355.1 - 2.8e-47 156.4 31.3 3.2e-08 32.8 0.7 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCF52355.1 - 2.6e-35 117.4 32.6 3.5e-06 26.4 0.2 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CCF52355.1 - 1.5e-24 86.0 19.5 2.7e-08 34.2 0.0 6.4 3 3 3 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52355.1 - 2.4e-22 78.6 21.2 4.6e-12 45.7 0.4 6.5 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCF52355.1 - 8.7e-18 62.7 22.7 0.0014 18.2 0.4 8.9 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52355.1 - 4.3e-16 57.9 17.4 0.035 14.7 0.0 9.2 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCF52355.1 - 5.5e-15 55.4 13.2 2.5e-05 24.5 0.1 6.0 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCF52355.1 - 9.6e-13 46.9 14.6 0.00019 20.9 0.1 8.0 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF52355.1 - 2.5e-11 42.8 6.0 0.089 13.0 0.0 7.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCF52355.1 - 1.1e-08 34.8 5.5 0.14 12.0 0.0 6.8 3 2 2 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CCF52355.1 - 2.8e-07 30.5 15.7 0.00082 19.4 0.9 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCF52355.1 - 0.00012 22.3 15.8 0.27 11.7 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCF52355.1 - 0.00044 20.0 9.3 0.00079 19.2 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3808 PF10300.4 CCF52355.1 - 0.0023 16.5 1.3 0.003 16.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) NARP1 PF12569.3 CCF52355.1 - 0.035 12.8 0.4 0.035 12.8 0.3 4.4 3 2 2 5 5 4 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 CCF52355.1 - 0.036 13.8 16.2 0.52 10.1 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.10 CCF52355.1 - 0.14 12.0 1.4 6.7 6.6 0.0 3.7 4 1 0 5 5 5 0 MAS20 protein import receptor PAS_4 PF08448.5 CCF52355.1 - 0.22 11.6 0.7 3 7.9 0.0 2.9 3 0 0 3 3 3 0 PAS fold Herpes_DNAp_acc PF04929.7 CCF52355.1 - 8 5.3 8.0 0.27 10.1 1.4 1.5 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Glyco_transf_28 PF03033.15 CCF52356.1 - 3.1e-25 88.5 0.0 7e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCF52356.1 - 2.1e-13 49.5 0.0 1.6e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CCF52356.1 - 4.7e-11 42.8 0.1 1.3e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 CCF52356.1 - 0.00038 20.4 0.0 0.00038 20.4 0.0 3.0 3 0 0 3 3 2 1 Pleckstrin homology domain PH_3 PF14593.1 CCF52356.1 - 0.00046 20.0 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 CCF52356.1 - 0.00074 18.1 0.0 0.0013 17.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Spore_coat_CotO PF14153.1 CCF52356.1 - 0.0046 16.4 15.1 0.0046 16.4 10.5 2.9 4 0 0 4 4 4 1 Spore coat protein CotO Tim54 PF11711.3 CCF52356.1 - 0.011 14.3 12.6 0.047 12.2 8.7 2.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PH_11 PF15413.1 CCF52356.1 - 0.017 15.3 0.3 0.1 12.8 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Plasmodium_Vir PF05795.6 CCF52356.1 - 0.8 8.8 6.9 2.7 7.1 4.8 1.9 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CCF52356.1 - 1.1 6.9 14.4 0.025 12.3 5.4 1.4 2 0 0 2 2 2 0 Ycf1 Nop14 PF04147.7 CCF52356.1 - 2.4 5.9 42.0 0.0062 14.5 18.9 2.2 2 0 0 2 2 2 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 CCF52357.1 - 3.8e-40 138.2 35.9 9.2e-39 133.7 24.9 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 ALAD PF00490.16 CCF52358.1 - 7.9e-121 402.8 0.0 9.2e-121 402.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Amidohydro_2 PF04909.9 CCF52358.1 - 0.061 12.8 0.1 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase SCP2 PF02036.12 CCF52359.1 - 1.1e-10 41.6 2.2 1.8e-06 28.1 0.2 2.1 1 1 1 2 2 2 2 SCP-2 sterol transfer family HALZ PF02183.13 CCF52361.1 - 0.047 13.4 0.4 0.076 12.7 0.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Acetyltransf_9 PF13527.1 CCF52361.1 - 0.074 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HECA PF15353.1 CCF52361.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Headcase protein family homologue MFS_1 PF07690.11 CCF52363.1 - 3.7e-45 154.1 45.7 3.7e-45 154.1 31.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCF52363.1 - 3.6e-19 68.3 18.3 3.6e-19 68.3 12.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 CCF52364.1 - 1.3e-05 25.2 0.6 3e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family ATP-synt_F PF01990.12 CCF52365.1 - 6.8e-29 100.1 0.0 7.7e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 CCF52365.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Hist_deacetyl PF00850.14 CCF52366.1 - 3.9e-80 269.4 0.0 6.5e-80 268.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain GYF PF02213.11 CCF52367.1 - 4.6e-19 67.7 0.3 8.6e-19 66.8 0.2 1.5 1 0 0 1 1 1 1 GYF domain CTDII PF01556.13 CCF52368.1 - 2.5e-27 94.6 0.2 2.1e-21 75.6 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CCF52368.1 - 2.5e-23 81.5 4.4 4e-23 80.9 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCF52368.1 - 3.9e-10 39.6 16.9 3.9e-10 39.6 11.7 2.4 3 0 0 3 3 3 1 DnaJ central domain LexA_DNA_bind PF01726.11 CCF52368.1 - 0.038 13.5 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain Lar_restr_allev PF14354.1 CCF52368.1 - 0.83 10.0 5.0 6.9 7.0 1.6 2.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar adh_short PF00106.20 CCF52370.1 - 1.3e-09 38.1 0.5 5.3e-09 36.2 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF52370.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 CCF52370.1 - 0.00031 20.4 0.1 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 CCF52370.1 - 0.0015 18.2 0.3 0.0048 16.5 0.1 1.9 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 CCF52370.1 - 0.0053 17.1 0.3 0.034 14.5 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCF52370.1 - 0.013 14.9 0.0 0.089 12.2 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA LMWPc PF01451.16 CCF52371.1 - 1.1e-29 103.4 0.0 1.3e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF2346 PF09803.4 CCF52372.1 - 5.4e-06 26.1 6.5 5.4e-06 26.1 2.5 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2346) DHC_N1 PF08385.7 CCF52374.1 - 1.7e-192 640.9 9.3 9.4e-192 638.4 4.3 2.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CCF52374.1 - 5.8e-131 436.7 0.9 5.8e-131 436.7 0.6 3.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CCF52374.1 - 2.1e-78 263.0 0.0 2.2e-77 259.6 0.0 2.8 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CCF52374.1 - 1.8e-27 95.7 0.0 1.7e-14 53.7 0.0 5.4 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CCF52374.1 - 1.6e-21 76.4 0.0 4.5e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CCF52374.1 - 1.8e-19 69.8 0.0 1.2e-18 67.2 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CCF52374.1 - 4.9e-13 49.3 0.2 0.018 15.1 0.0 5.8 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 CCF52374.1 - 1.2e-11 44.8 0.0 0.0089 16.2 0.0 4.8 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCF52374.1 - 1.2e-08 35.1 7.9 0.031 14.2 0.4 7.0 6 1 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.1 CCF52374.1 - 5.9e-08 32.6 0.6 0.3 10.9 0.0 5.4 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.1 CCF52374.1 - 6e-08 32.3 0.5 0.3 10.8 0.0 4.7 4 0 0 4 4 4 2 Part of AAA domain AAA_17 PF13207.1 CCF52374.1 - 3.2e-07 31.2 0.0 5.2 7.9 0.0 5.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CCF52374.1 - 7.1e-07 29.5 0.0 0.29 11.4 0.0 4.8 4 0 0 4 4 4 1 AAA domain T2SE PF00437.15 CCF52374.1 - 4.4e-06 25.7 0.0 0.098 11.5 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 CCF52374.1 - 1.8e-05 24.0 0.7 0.47 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCF52374.1 - 0.00016 21.7 0.0 9 6.3 0.0 4.9 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_14 PF13173.1 CCF52374.1 - 0.00017 21.4 0.0 0.53 10.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CCF52374.1 - 0.0002 20.9 0.3 4.6 6.6 0.0 4.4 4 0 0 4 4 4 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 CCF52374.1 - 0.0015 18.0 4.4 0.36 10.2 0.0 3.7 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_29 PF13555.1 CCF52374.1 - 0.0018 17.7 0.0 8.3 6.0 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CCF52374.1 - 0.0094 16.1 0.0 8.2 6.6 0.0 4.1 4 0 0 4 4 4 0 RNA helicase ABC_tran PF00005.22 CCF52374.1 - 0.019 15.2 2.7 22 5.3 0.0 4.9 5 0 0 5 5 4 0 ABC transporter AAA_25 PF13481.1 CCF52374.1 - 0.025 13.9 3.4 1 8.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain ResIII PF04851.10 CCF52374.1 - 0.081 12.7 0.0 3.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 CCF52374.1 - 0.15 11.5 0.2 60 3.1 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 CCF52374.1 - 0.23 10.9 4.8 2.7 7.4 0.0 4.2 6 0 0 6 6 6 0 AAA domain Pkinase PF00069.20 CCF52375.1 - 6.9e-52 176.1 0.0 1.2e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52375.1 - 7.5e-23 80.9 0.0 4.5e-22 78.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Snurportin1 PF11538.3 CCF52375.1 - 0.0031 17.2 2.7 0.012 15.3 1.9 2.0 1 0 0 1 1 1 1 Snurportin1 Pox_ser-thr_kin PF05445.6 CCF52375.1 - 0.0097 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CCF52375.1 - 0.13 11.9 6.1 0.17 11.6 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Calpain_III PF01067.17 CCF52376.1 - 9.2e-23 80.5 0.0 3.1e-09 36.6 0.0 5.1 3 2 0 3 3 3 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CCF52376.1 - 1.9e-11 43.5 0.0 2.5e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 CCF52376.1 - 6.8e-06 25.8 0.8 0.016 15.0 0.0 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain HA2 PF04408.18 CCF52377.1 - 3e-18 65.7 0.0 6.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCF52377.1 - 1.3e-16 60.4 0.0 3.2e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCF52377.1 - 1.9e-10 40.4 0.0 6e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Snf7 PF03357.16 CCF52378.1 - 1.1e-17 63.9 12.7 1.1e-17 63.9 8.8 2.1 1 1 1 2 2 2 1 Snf7 Ribosomal_S30 PF04758.9 CCF52379.1 - 4.8e-30 103.1 7.7 5.4e-30 102.9 5.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 S10_plectin PF03501.10 CCF52380.1 - 7.8e-41 137.8 0.1 9.4e-41 137.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 CCF52380.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.6 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Podoplanin PF05808.6 CCF52381.1 - 0.42 10.1 3.0 0.52 9.8 2.1 1.2 1 0 0 1 1 1 0 Podoplanin E1-E2_ATPase PF00122.15 CCF52383.1 - 5.6e-67 225.1 2.9 5.6e-67 225.1 2.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF52383.1 - 3.5e-44 150.4 5.6 5.4e-44 149.8 2.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF52383.1 - 5.2e-33 115.2 0.0 1.6e-31 110.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF52383.1 - 7.3e-23 79.8 0.1 1.9e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCF52383.1 - 3.9e-20 71.5 0.0 8e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCF52383.1 - 9.5e-18 65.0 0.0 7.2e-17 62.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCF52383.1 - 3.6e-08 33.2 1.3 9.1e-06 25.4 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCF52383.1 - 0.0058 16.8 0.0 0.036 14.3 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase L31 PF09784.4 CCF52384.1 - 1.5e-42 143.8 0.6 1.7e-42 143.6 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 SNF2_N PF00176.18 CCF52385.1 - 2.6e-65 220.1 0.0 4.5e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CCF52385.1 - 1.8e-51 174.7 0.4 3.5e-51 173.7 0.3 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 CCF52385.1 - 5e-12 45.5 0.0 1.9e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCF52385.1 - 3.4e-09 35.9 0.0 1.1e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CCF52385.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCF52385.1 - 0.0048 17.0 0.1 0.32 11.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain Galactosyl_T PF01762.16 CCF52386.1 - 3.9e-10 39.6 0.7 0.00036 20.1 0.0 4.0 3 1 1 4 4 4 3 Galactosyltransferase Arrestin_C PF02752.17 CCF52387.1 - 1.7e-17 63.8 0.0 4.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCF52387.1 - 0.034 13.9 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain He_PIG PF05345.7 CCF52388.1 - 0.0021 18.0 0.0 0.0056 16.6 0.0 1.7 1 0 0 1 1 1 1 Putative Ig domain CitG PF01874.11 CCF52389.1 - 0.0092 15.2 0.0 0.0097 15.1 0.0 1.0 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase DUF3456 PF11938.3 CCF52389.1 - 0.069 13.1 0.6 0.096 12.6 0.4 1.3 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP DUF3452 PF11934.3 CCF52389.1 - 0.071 12.4 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) ADK PF00406.17 CCF52390.1 - 3.1e-57 192.6 0.0 4e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCF52390.1 - 6.6e-14 51.2 0.0 1.5e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCF52390.1 - 0.00012 21.9 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF52390.1 - 0.00028 20.0 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 CCF52390.1 - 0.0048 17.0 0.1 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCF52390.1 - 0.019 15.7 0.0 0.035 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCF52390.1 - 0.04 14.0 0.4 0.44 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.12 CCF52390.1 - 0.045 13.1 0.1 3.1 7.1 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase AAA_18 PF13238.1 CCF52390.1 - 0.054 13.8 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 CCF52390.1 - 0.076 12.4 0.1 15 4.9 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase AAA_5 PF07728.9 CCF52390.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Apo-CII PF05355.6 CCF52390.1 - 0.098 12.5 0.1 0.62 9.9 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein C-II TPR_11 PF13414.1 CCF52391.1 - 7.5e-26 89.5 15.5 6.2e-10 38.5 0.5 6.7 5 2 2 7 7 7 5 TPR repeat TPR_2 PF07719.12 CCF52391.1 - 9.1e-19 65.8 11.7 0.031 14.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.23 CCF52391.1 - 9.7e-19 66.1 4.3 0.0053 16.3 0.0 7.7 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCF52391.1 - 2.6e-14 53.4 16.1 0.00011 22.7 0.1 7.0 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCF52391.1 - 7.5e-12 44.1 0.5 0.64 9.9 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52391.1 - 2.5e-10 40.0 26.2 0.058 14.0 0.2 8.9 6 1 4 10 10 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCF52391.1 - 3.8e-10 39.1 0.4 0.11 12.7 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52391.1 - 3.2e-06 26.9 22.0 0.0018 18.1 0.5 6.1 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF52391.1 - 0.00022 21.4 11.5 4.6 7.6 0.3 7.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF52391.1 - 0.00022 20.7 1.6 15 5.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCF52391.1 - 0.0015 18.3 9.2 0.015 15.1 1.2 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCF52391.1 - 0.0018 18.3 10.1 0.11 12.6 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCF52391.1 - 0.0024 18.2 3.4 59 4.4 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Macoilin PF09726.4 CCF52391.1 - 2 6.5 23.6 4.8 5.3 16.3 1.5 1 0 0 1 1 1 0 Transmembrane protein LysM PF01476.15 CCF52392.1 - 1.6e-15 56.7 0.3 3.9e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain DUF605 PF04652.11 CCF52392.1 - 0.89 8.8 33.6 1.3 8.3 23.3 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CCF52392.1 - 3.2 5.8 38.1 3.8 5.6 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CCF52392.1 - 8.6 4.4 34.9 12 4.0 24.2 1.1 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 CCF52392.1 - 8.9 4.6 33.3 11 4.3 23.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RF-1 PF00472.15 CCF52394.1 - 1.9e-37 127.5 1.9 4.5e-37 126.3 1.3 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCF52394.1 - 1.7e-32 111.5 0.1 3.8e-32 110.4 0.1 1.6 1 0 0 1 1 1 1 PCRF domain HLH PF00010.21 CCF52395.1 - 2.3e-08 33.5 0.3 6.3e-08 32.2 0.2 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 CCF52395.1 - 3.1 7.8 11.6 0.14 12.1 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Carboxyl_trans PF01039.17 CCF52396.1 - 2e-145 484.9 0.1 2.4e-145 484.6 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CCF52396.1 - 0.017 14.3 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) SopD PF11047.3 CCF52396.1 - 0.2 10.5 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D AAA PF00004.24 CCF52397.1 - 6.9e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCF52397.1 - 1.2e-05 24.2 0.2 0.11 11.1 0.0 2.8 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCF52397.1 - 2.4e-05 25.1 0.0 9.9e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF52397.1 - 6e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCF52397.1 - 0.00013 21.0 0.0 0.00033 19.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCF52397.1 - 0.00018 21.2 0.1 0.001 18.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CCF52397.1 - 0.00056 19.3 0.0 0.18 11.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF52397.1 - 0.0023 17.9 0.0 0.69 9.8 0.0 3.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CCF52397.1 - 0.0059 16.7 0.1 0.031 14.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CCF52397.1 - 0.0099 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF52397.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCF52397.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CCF52397.1 - 0.042 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 CCF52397.1 - 0.082 12.6 0.2 0.35 10.5 0.0 2.0 1 1 1 2 2 2 0 NTPase KaiC PF06745.8 CCF52397.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 CCF52397.1 - 0.27 10.0 0.0 0.56 9.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CHORD PF04968.7 CCF52398.1 - 1.4e-47 159.7 11.3 2.8e-24 85.1 2.4 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 CCF52398.1 - 1.4e-07 31.9 0.0 2.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.14 CCF52398.1 - 0.012 15.2 8.9 0.12 12.0 1.3 3.1 3 1 0 3 3 3 0 BTK motif DUF2733 PF10813.3 CCF52398.1 - 0.091 12.3 2.8 4.5 6.9 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Shugoshin_N PF07558.6 CCF52399.1 - 0.03 14.0 0.5 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GAS PF13851.1 CCF52399.1 - 0.035 13.2 5.4 1.4 8.0 0.0 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.8 CCF52399.1 - 0.04 12.8 5.7 0.44 9.4 0.1 2.8 3 0 0 3 3 3 0 HAP1 N-terminal conserved region Filament PF00038.16 CCF52399.1 - 0.15 11.4 8.5 0.082 12.3 3.5 2.2 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 CCF52399.1 - 0.28 10.9 10.4 0.072 12.8 0.9 3.0 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 CCF52399.1 - 9.8 4.3 14.5 0.32 9.2 3.4 2.2 2 0 0 2 2 2 0 Transmembrane protein SOXp PF12336.3 CCF52400.1 - 0.058 14.0 0.1 10 6.8 0.0 2.5 2 0 0 2 2 2 0 SOX transcription factor Fungal_trans PF04082.13 CCF52401.1 - 2.2e-21 75.8 0.0 3.5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF52401.1 - 1.9e-06 27.6 8.7 3.9e-06 26.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR PF15222.1 CCF52401.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Kidney androgen-regulated Lactamase_B_2 PF12706.2 CCF52402.1 - 4e-27 95.0 0.2 7.3e-26 90.9 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCF52402.1 - 1e-07 31.8 0.0 2.2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF52402.1 - 0.13 11.9 0.9 0.31 10.6 0.6 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Epimerase PF01370.16 CCF52403.1 - 3.2e-42 144.6 0.0 5.1e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCF52403.1 - 5.4e-10 38.4 0.0 9e-10 37.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCF52403.1 - 6.7e-09 35.0 0.0 5.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CCF52403.1 - 1.7e-07 30.4 0.0 2.7e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCF52403.1 - 9.1e-06 24.7 0.4 0.003 16.5 0.1 3.2 3 1 0 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCF52403.1 - 0.013 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 CCF52403.1 - 0.035 14.0 0.5 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase zf-Mss51 PF13824.1 CCF52404.1 - 1.7e-22 78.9 1.7 3.2e-22 78.1 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 UEV PF05743.8 CCF52405.1 - 3.8e-39 133.0 0.0 6e-39 132.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CCF52405.1 - 1.2e-27 95.3 0.5 2.2e-27 94.4 0.3 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 CCF52405.1 - 0.0025 17.2 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Baculo_PEP_C PF04513.7 CCF52405.1 - 0.069 12.9 0.7 0.15 11.8 0.5 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 CCF52405.1 - 0.2 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SAE2 PF08573.5 CCF52406.1 - 2.6e-09 37.6 10.4 1.3e-06 28.9 0.3 3.5 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Cytochrom_C PF00034.16 CCF52406.1 - 0.027 15.2 0.5 0.11 13.3 0.3 2.0 1 0 0 1 1 1 0 Cytochrome c RasGEF PF00617.14 CCF52407.1 - 5.1e-62 208.9 0.0 1e-61 207.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCF52407.1 - 1.6e-28 98.8 2.0 5.1e-28 97.2 0.5 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCF52407.1 - 5.1e-14 51.3 0.1 9.8e-14 50.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF52407.1 - 3.3e-12 45.7 0.1 6.9e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF52407.1 - 7.6e-11 41.3 0.0 1.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 CCF52407.1 - 0.00036 20.3 3.5 0.34 10.8 0.2 2.5 2 0 0 2 2 2 2 WW domain Sec66 PF09802.4 CCF52408.1 - 2.4e-46 157.5 0.0 3.7e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 LcrG PF07216.7 CCF52408.1 - 0.21 11.6 0.2 0.21 11.6 0.1 2.5 2 1 1 3 3 3 0 LcrG protein DUF3708 PF12501.3 CCF52408.1 - 0.74 9.6 6.1 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Pkinase PF00069.20 CCF52410.1 - 2.4e-50 171.1 0.0 3.7e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52410.1 - 2e-45 154.9 0.0 2.9e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TEA PF01285.13 CCF52411.1 - 5e-34 118.2 0.0 2.1e-33 116.1 0.0 1.9 1 1 0 1 1 1 1 TEA/ATTS domain family TFIIF_alpha PF05793.7 CCF52411.1 - 1.3 7.2 7.7 8 4.6 2.3 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2361 PF10153.4 CCF52412.1 - 0.19 11.9 2.6 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) FYDLN_acid PF09538.5 CCF52412.1 - 0.67 10.5 11.7 0.046 14.3 4.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Macoilin PF09726.4 CCF52412.1 - 2.4 6.3 5.1 3.5 5.7 3.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Apc15p PF05841.6 CCF52412.1 - 4.5 8.0 8.0 0.27 11.9 1.0 2.1 2 1 0 2 2 2 0 Apc15p protein P34-Arc PF04045.9 CCF52413.1 - 1.2e-104 348.8 0.0 1.5e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Lactamase_B_3 PF13483.1 CCF52414.1 - 5.8e-07 29.3 0.1 1.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 CCF52414.1 - 7.3e-05 22.3 0.6 9.7e-05 21.9 0.1 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain F-box-like PF12937.2 CCF52415.1 - 3.5e-07 29.8 1.2 6.6e-07 28.9 0.8 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF52415.1 - 4.6e-06 26.1 0.2 8.5e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain fn3 PF00041.16 CCF52416.1 - 5.4e-05 23.2 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain PTCB-BRCT PF12738.2 CCF52416.1 - 0.00034 20.4 0.0 0.0011 18.7 0.0 2.0 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CCF52416.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 CCF52416.1 - 0.0018 18.0 0.2 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) CDC27 PF09507.5 CCF52416.1 - 0.17 11.0 10.6 0.25 10.5 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Beta-Casp PF10996.3 CCF52417.1 - 1.6e-22 79.7 0.0 3.8e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.1 CCF52417.1 - 1e-21 77.7 0.0 6.6e-20 71.9 0.0 2.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.2 CCF52417.1 - 1.1e-06 28.3 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF52417.1 - 0.0044 16.6 0.7 0.045 13.3 0.1 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily MIP PF00230.15 CCF52418.1 - 2.6e-39 135.0 11.6 3.6e-39 134.5 8.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein T2SM PF04612.7 CCF52418.1 - 0.11 12.3 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Peptidase_S8 PF00082.17 CCF52419.1 - 2.4e-57 194.2 1.0 3.9e-57 193.5 0.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CCF52419.1 - 1e-28 98.9 0.2 2.3e-28 97.7 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain LEA_2 PF03168.8 CCF52420.1 - 0.0002 21.6 0.1 0.00054 20.2 0.1 1.8 1 1 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 CCF52420.1 - 0.0018 17.5 1.3 0.0028 16.8 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) ODV-E18 PF10717.4 CCF52420.1 - 0.079 12.4 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Vps54 PF07928.7 CCF52421.1 - 6.7e-54 181.6 3.0 1.2e-53 180.8 0.9 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 CCF52421.1 - 9.3e-07 28.0 2.9 9.3e-07 28.0 2.0 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Vps39_1 PF10366.4 CCF52421.1 - 0.05 13.6 0.2 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 CCF52422.1 - 5e-21 73.7 4.9 3.9e-06 26.5 0.4 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 CCF52422.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Exo_endo_phos PF03372.18 CCF52423.1 - 3.5e-22 79.5 0.2 4.5e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UQ_con PF00179.21 CCF52424.1 - 4e-37 126.7 0.1 5.3e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCF52424.1 - 0.017 14.9 0.1 0.023 14.5 0.1 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 CCF52424.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain PCMT PF01135.14 CCF52425.1 - 1.5e-65 220.7 0.0 1.7e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CCF52425.1 - 5.7e-07 30.1 0.0 8.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF52425.1 - 5.1e-06 26.1 0.0 7.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF52425.1 - 7.8e-05 22.6 0.1 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF52425.1 - 0.00019 21.7 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF52425.1 - 0.00081 19.8 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF52425.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCF52425.1 - 0.0025 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CCF52425.1 - 0.0034 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CCF52425.1 - 0.055 12.8 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Guanylate_kin PF00625.16 CCF52426.1 - 2.9e-58 196.3 0.0 3.5e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 CCF52426.1 - 9.1e-08 32.2 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CCF52426.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCF52426.1 - 1.8e-05 25.0 0.0 0.0016 18.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.1 CCF52426.1 - 2.4e-05 24.4 0.0 0.00019 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCF52426.1 - 0.0001 22.1 0.0 0.0013 18.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF52426.1 - 0.00012 22.8 0.1 0.00053 20.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCF52426.1 - 0.00034 20.3 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 CCF52426.1 - 0.00057 19.8 0.0 0.0016 18.3 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 CCF52426.1 - 0.00065 19.1 0.0 0.0016 17.8 0.0 1.7 1 1 0 1 1 1 1 Thymidylate kinase ABC_tran PF00005.22 CCF52426.1 - 0.0009 19.5 0.0 0.0018 18.6 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CCF52426.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 CCF52426.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCF52426.1 - 0.0027 17.8 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 CCF52426.1 - 0.0028 17.1 0.1 0.0074 15.7 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 CCF52426.1 - 0.0042 17.0 0.0 0.03 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCF52426.1 - 0.0066 16.1 0.0 0.021 14.5 0.0 1.7 2 1 0 2 2 2 1 NTPase NACHT PF05729.7 CCF52426.1 - 0.0068 16.0 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 1 1 NACHT domain KAP_NTPase PF07693.9 CCF52426.1 - 0.0094 14.9 0.1 0.026 13.5 0.0 1.8 1 1 0 1 1 1 1 KAP family P-loop domain T2SE PF00437.15 CCF52426.1 - 0.0094 14.8 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 CCF52426.1 - 0.013 15.2 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 CCF52426.1 - 0.024 15.1 0.0 0.059 13.8 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein AAA PF00004.24 CCF52426.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 CCF52426.1 - 0.073 11.8 0.0 0.13 11.0 0.0 1.4 1 1 0 1 1 1 0 ArgK protein cobW PF02492.14 CCF52426.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2786 PF10979.3 CCF52427.1 - 4.1e-11 42.4 0.5 1e-10 41.1 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Amnionless PF14828.1 CCF52431.1 - 0.13 10.7 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Nucleoporin_C PF03177.9 CCF52432.1 - 1e-69 235.6 0.1 6.4e-69 233.0 0.1 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCF52432.1 - 7.4e-16 57.9 0.0 1.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 CCF52433.1 - 7e-34 114.4 10.6 1.1e-09 37.7 0.2 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCF52433.1 - 0.0002 21.1 0.0 0.036 13.7 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 CCF52433.1 - 0.007 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCF52433.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 LisH Fungal_trans PF04082.13 CCF52434.1 - 6.3e-14 51.4 0.0 9.4e-13 47.6 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CCF52434.1 - 1.1e-06 28.5 8.7 0.0008 19.6 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF52434.1 - 0.00045 20.3 7.0 0.035 14.4 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCF52434.1 - 0.18 11.7 2.9 5.2 7.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF52434.1 - 0.23 11.7 3.6 0.39 11.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain V-SNARE_C PF12352.3 CCF52435.1 - 1.1e-18 67.0 0.8 2.3e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Erp_C PF06780.6 CCF52435.1 - 0.037 13.8 0.2 0.073 12.9 0.2 1.6 1 1 0 1 1 1 0 Erp protein C-terminus Baculo_PEP_C PF04513.7 CCF52435.1 - 2.7 7.7 6.0 19 5.1 0.5 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRM1_C PF08767.6 CCF52436.1 - 5.3e-127 423.1 0.1 5.3e-127 423.1 0.0 2.7 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CCF52436.1 - 7.1e-41 139.5 5.0 1.3e-40 138.7 0.5 3.6 2 1 1 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CCF52436.1 - 4.1e-15 55.4 1.5 2.5e-14 52.9 1.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ank_2 PF12796.2 CCF52437.1 - 1.4e-45 153.5 3.7 1.5e-18 66.9 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCF52437.1 - 4.4e-39 130.3 6.7 1.4e-07 30.9 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 CCF52437.1 - 2.9e-35 119.9 2.0 1.1e-11 44.8 0.0 5.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 CCF52437.1 - 7.2e-32 111.2 7.0 1.7e-19 70.6 0.2 2.3 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 CCF52437.1 - 1.1e-26 90.1 5.4 0.00012 22.0 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 CCF52437.1 - 2.1e-26 91.3 7.8 5.7e-05 23.2 0.0 6.7 2 2 5 7 7 7 5 Ankyrin repeats (many copies) GDPD PF03009.12 CCF52437.1 - 7.8e-11 41.9 0.0 2.9e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF2423 PF10338.4 CCF52438.1 - 1.5e-13 50.4 5.1 2.4e-13 49.7 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Abhydrolase_6 PF12697.2 CCF52439.1 - 6.9e-12 45.7 1.5 1.7e-11 44.4 1.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52439.1 - 7.2e-07 29.0 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 CCF52439.1 - 2.4e-05 23.3 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 CCF52439.1 - 0.00081 18.6 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF915 PF06028.6 CCF52439.1 - 0.016 14.3 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CCF52439.1 - 0.031 13.8 0.2 0.12 11.8 0.0 2.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold XPG_I PF00867.13 CCF52440.1 - 6.8e-21 74.1 0.0 1.7e-20 72.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCF52440.1 - 2.4e-06 27.7 0.0 5.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DDE_Tnp_1_6 PF13751.1 CCF52440.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain XPG_I_2 PF12813.2 CCF52440.1 - 0.2 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing DUF2413 PF10310.4 CCF52440.1 - 3.2 6.4 5.2 1 8.1 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) COesterase PF00135.23 CCF52441.1 - 2.5e-76 257.5 0.0 9.8e-76 255.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF52441.1 - 4.2e-08 33.0 1.3 0.00017 21.2 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Fasciclin PF02469.17 CCF52442.1 - 2.1e-17 63.3 0.0 4.3e-10 39.6 0.0 3.5 3 1 0 3 3 3 3 Fasciclin domain bZIP_1 PF00170.16 CCF52443.1 - 9.1e-08 31.9 8.0 1.6e-07 31.1 5.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCF52443.1 - 0.00089 19.0 5.4 0.0016 18.2 3.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper MatP PF06303.7 CCF52443.1 - 0.12 12.2 0.9 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome bZIP_Maf PF03131.12 CCF52443.1 - 2.2 8.6 13.6 0.21 11.8 5.4 2.2 2 1 0 2 2 2 0 bZIP Maf transcription factor Glutaredoxin PF00462.19 CCF52444.1 - 1.8e-16 59.8 0.1 2.8e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin GTP_EFTU PF00009.22 CCF52445.1 - 4.6e-44 150.1 0.0 7e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCF52445.1 - 2.3e-28 98.1 0.0 4.2e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CCF52445.1 - 2.5e-19 68.9 0.0 6.6e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 CCF52445.1 - 2.2e-09 37.8 0.0 4.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCF52445.1 - 1.8e-06 27.8 0.0 3.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 CCF52445.1 - 1.1e-05 25.1 0.0 2.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCF52445.1 - 1.2e-05 25.3 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 CCF52445.1 - 0.00051 19.4 0.0 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Ras family Septin PF00735.13 CCF52445.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 CCF52445.1 - 0.037 13.8 0.1 1.1 9.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family MFS_2 PF13347.1 CCF52446.1 - 5.7e-05 21.6 4.5 5.7e-05 21.6 3.1 3.1 4 0 0 4 4 4 1 MFS/sugar transport protein NIPSNAP PF07978.8 CCF52446.1 - 0.018 14.9 1.1 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 NIPSNAP MFS_1_like PF12832.2 CCF52446.1 - 0.09 12.5 0.0 0.09 12.5 0.0 3.8 4 1 0 4 4 4 0 MFS_1 like family PDCD2_C PF04194.8 CCF52447.1 - 7.4e-22 77.6 0.1 5.9e-20 71.5 0.0 4.7 5 1 0 5 5 5 2 Programmed cell death protein 2, C-terminal putative domain Nop14 PF04147.7 CCF52447.1 - 0.008 14.1 9.3 0.011 13.6 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family Na_trans_assoc PF06512.8 CCF52447.1 - 0.086 12.7 3.3 0.15 12.0 2.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Cwf_Cwc_15 PF04889.7 CCF52447.1 - 1.2 8.7 20.2 3.8 7.1 3.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cornichon PF03311.9 CCF52448.1 - 3e-53 179.3 10.5 3.4e-53 179.1 7.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 CCF52448.1 - 0.41 10.1 9.4 1.3 8.4 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF1634 PF07843.6 CCF52448.1 - 1.3 8.7 5.1 0.28 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) AHS2 PF02626.10 CCF52449.1 - 1.1e-61 208.5 0.0 1.6e-61 208.0 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 CCF52449.1 - 6.8e-56 188.8 0.1 1.2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCF52449.1 - 8.4e-33 112.7 0.0 2.1e-32 111.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 CCF52449.1 - 5.2e-31 107.6 0.0 1.3e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 Biotin_carb_C PF02785.14 CCF52449.1 - 9.3e-28 96.3 0.0 2.5e-26 91.7 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCF52449.1 - 2.9e-19 69.5 0.1 6e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCF52449.1 - 1.8e-12 46.6 0.6 4.9e-12 45.3 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CCF52449.1 - 4.1e-10 39.3 0.0 9.2e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 CCF52449.1 - 4.7e-10 38.7 0.0 3.4e-09 35.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCF52449.1 - 4.4e-07 29.3 0.0 1.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCF52449.1 - 8.8e-06 25.3 0.0 4.6e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCF52449.1 - 8.7e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 CCF52449.1 - 0.0013 17.9 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCF52449.1 - 0.045 13.2 0.1 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Mo25 PF08569.6 CCF52449.1 - 0.14 11.2 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Mo25-like LamB_YcsF PF03746.11 CCF52450.1 - 4.4e-69 232.2 0.0 9.2e-69 231.2 0.0 1.4 1 1 0 1 1 1 1 LamB/YcsF family B56 PF01603.15 CCF52451.1 - 4.3e-170 565.7 10.5 5.2e-170 565.4 7.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Prenyltrans PF00432.16 CCF52452.1 - 0.084 12.4 1.1 4.1 7.0 0.2 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat RQC PF09382.5 CCF52453.1 - 3.3e-25 87.8 0.1 6.4e-25 86.9 0.1 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CCF52453.1 - 1.4e-21 76.6 0.5 3.9e-21 75.2 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF52453.1 - 1.2e-19 69.9 0.0 3.6e-18 65.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF52453.1 - 0.023 14.5 0.0 0.093 12.5 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit HRDC PF00570.18 CCF52453.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 HRDC domain Fib_alpha PF08702.5 CCF52454.1 - 0.66 10.0 5.3 1.3 9.1 3.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Casc1 PF12366.3 CCF52454.1 - 4.6 6.6 6.6 16 4.9 4.4 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 IncA PF04156.9 CCF52454.1 - 5.6 6.5 14.1 11 5.5 9.8 1.5 1 0 0 1 1 1 0 IncA protein DUF1674 PF07896.7 CCF52455.1 - 2e-12 47.1 7.3 4.2e-12 46.0 5.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) MFS_1 PF07690.11 CCF52456.1 - 2.3e-09 36.4 23.3 2.3e-09 36.4 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mis14 PF08641.7 CCF52457.1 - 2.5e-06 27.6 7.1 2.5e-06 27.6 4.9 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Nsp1_C PF05064.8 CCF52457.1 - 0.075 12.6 1.3 0.29 10.7 0.0 2.5 3 0 0 3 3 3 0 Nsp1-like C-terminal region Stirrup PF09061.1 CCF52457.1 - 0.22 11.4 1.0 0.41 10.5 0.1 1.9 2 0 0 2 2 2 0 Stirrup FlaG PF03646.10 CCF52457.1 - 0.75 9.9 0.1 0.75 9.9 0.0 2.8 3 1 0 3 3 3 0 FlaG protein Ribosomal_L27e PF01777.13 CCF52457.1 - 1.1 9.4 4.9 0.46 10.6 1.1 2.2 2 1 0 2 2 2 0 Ribosomal L27e protein family DUF4576 PF15144.1 CCF52458.1 - 0.066 12.8 0.0 0.25 10.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF2315 PF10231.4 CCF52459.1 - 3.3e-14 52.8 1.0 1.9e-10 40.6 0.6 2.5 2 1 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) CSTF2_hinge PF14327.1 CCF52460.1 - 3.8e-30 103.8 2.1 3.8e-30 103.8 1.5 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 CCF52460.1 - 1.5e-23 82.1 0.1 2.5e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52460.1 - 1.3e-16 60.3 0.0 2.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CCF52460.1 - 8.8e-12 44.1 5.8 8.8e-12 44.1 4.1 2.1 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 CCF52460.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhoGEF PF00621.15 CCF52461.1 - 1.5e-12 47.7 0.0 9.4e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain Prefoldin_2 PF01920.15 CCF52462.1 - 2.7e-18 65.6 7.9 4.2e-18 65.0 5.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Sipho_Gp157 PF05565.6 CCF52462.1 - 0.061 12.9 6.0 1.7 8.1 1.0 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 XhlA PF10779.4 CCF52462.1 - 0.067 13.1 0.9 0.067 13.1 0.6 1.9 2 0 0 2 2 2 0 Haemolysin XhlA DUF4140 PF13600.1 CCF52462.1 - 0.11 12.9 9.6 1.1 9.7 0.7 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.1 CCF52462.1 - 0.13 11.5 4.1 1.1 8.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) NPV_P10 PF05531.7 CCF52462.1 - 0.14 12.4 6.8 0.54 10.5 0.6 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 CCF52462.1 - 0.2 10.9 19.6 0.22 10.7 5.5 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.19 CCF52462.1 - 0.26 11.0 4.9 1.1 8.9 0.3 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Suppressor_APC PF11414.3 CCF52462.1 - 0.37 10.6 8.5 0.067 12.9 1.6 2.3 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein FemAB PF02388.11 CCF52462.1 - 0.61 8.7 6.6 0.12 11.0 1.6 1.7 1 1 1 2 2 2 0 FemAB family DUF2408 PF10303.4 CCF52462.1 - 0.7 10.0 5.1 0.97 9.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.3 CCF52462.1 - 0.95 9.3 11.0 1.9 8.3 1.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding RasGAP_C PF03836.10 CCF52462.1 - 1.2 8.7 10.1 0.22 11.1 2.4 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Seryl_tRNA_N PF02403.17 CCF52462.1 - 1.2 9.1 8.8 0.46 10.5 1.8 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.1 CCF52462.1 - 2 8.3 19.7 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.2 CCF52462.1 - 2.2 8.0 12.7 0.096 12.5 2.8 2.0 2 0 0 2 2 2 0 Tropomyosin like Baculo_PEP_C PF04513.7 CCF52462.1 - 2.4 7.9 9.4 28 4.5 6.5 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Osmo_CC PF08946.5 CCF52462.1 - 2.9 7.9 7.3 1.1 9.3 2.3 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF948 PF06103.6 CCF52462.1 - 3.2 7.6 5.3 3.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 CCF52462.1 - 3.5 7.1 14.2 3.4 7.2 1.2 2.4 2 1 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CCF52462.1 - 4.3 6.2 10.7 1.4 7.8 0.5 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 CCF52462.1 - 4.5 7.6 13.3 0.68 10.2 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) K-box PF01486.12 CCF52462.1 - 5 6.9 10.0 3 7.7 1.2 2.4 2 1 0 2 2 2 0 K-box region SlyX PF04102.7 CCF52462.1 - 6 7.3 13.3 2.3 8.6 1.6 2.5 2 1 0 2 2 2 0 SlyX FliD_C PF07195.7 CCF52462.1 - 7 5.8 9.8 72 2.5 6.8 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus MbeD_MobD PF04899.7 CCF52462.1 - 8.5 6.3 9.7 7.9 6.4 2.9 2.4 2 0 0 2 2 2 0 MbeD/MobD like Chalcone PF02431.10 CCF52463.1 - 4.4e-45 153.5 0.0 6.2e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Acetyltransf_1 PF00583.19 CCF52464.1 - 2.8e-15 56.1 0.0 4e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF52464.1 - 6.7e-13 48.6 0.1 9.5e-13 48.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF52464.1 - 0.00029 20.8 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF52464.1 - 0.00038 20.3 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF52464.1 - 0.0022 18.1 0.0 0.0027 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF52464.1 - 0.0046 16.6 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 CCF52464.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CCF52464.1 - 0.02 15.0 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SNARE PF05739.14 CCF52466.1 - 5.9e-07 29.0 1.0 5.9e-07 29.0 0.7 3.4 4 0 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 CCF52466.1 - 0.032 14.2 3.5 0.69 10.0 0.2 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus ADH_N PF08240.7 CCF52467.1 - 9.3e-16 57.5 0.5 1.6e-15 56.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF52467.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCF52467.1 - 0.068 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 CCF52467.1 - 0.15 11.2 1.8 0.32 10.1 1.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF1741 PF08427.5 CCF52470.1 - 9.5e-49 165.9 0.8 1.6e-48 165.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DDE_Tnp_1_assoc PF13808.1 CCF52470.1 - 0.023 14.3 0.1 0.43 10.2 0.0 2.8 2 0 0 2 2 2 0 DDE_Tnp_1-associated SEP PF08059.8 CCF52471.1 - 1.7e-25 89.1 0.0 3.3e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CCF52471.1 - 5.4e-17 61.6 0.0 8.9e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCF52471.1 - 9.7e-16 57.0 0.2 1.7e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Tim17 PF02466.14 CCF52472.1 - 3e-15 56.4 11.0 4e-15 55.9 7.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 CCF52472.1 - 0.7 9.2 5.3 1 8.6 3.4 1.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT tRNA_bind PF01588.15 CCF52473.1 - 1.3e-27 95.4 0.0 3.6e-27 94.0 0.0 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C PF00043.20 CCF52473.1 - 0.0017 18.2 1.4 0.0058 16.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF52473.1 - 0.0037 17.6 0.0 0.0037 17.6 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCF52473.1 - 0.032 14.1 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RNase_H2-Ydr279 PF09468.5 CCF52473.1 - 0.68 9.0 5.8 0.96 8.5 4.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 CCF52473.1 - 1.1 9.0 9.1 1.9 8.2 6.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short PF00106.20 CCF52474.1 - 0.00032 20.6 0.1 3.2 7.6 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase DUF3425 PF11905.3 CCF52475.1 - 2.3e-28 98.7 5.0 1.1e-27 96.6 3.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CCF52475.1 - 0.00011 22.0 7.4 0.00024 20.9 5.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor Tim54 PF11711.3 CCF52475.1 - 0.11 11.0 4.7 0.79 8.2 0.6 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 CCF52475.1 - 1.7 8.3 23.2 1.2 8.8 2.0 3.2 3 0 0 3 3 3 0 DDHD domain UDPGP PF01704.13 CCF52476.1 - 1.7e-49 168.4 0.0 2.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCF52476.1 - 0.093 12.8 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 MobA-like NTP transferase domain Ribosomal_L4 PF00573.17 CCF52477.1 - 1e-44 152.2 0.7 1.7e-44 151.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCF52477.1 - 6.1e-29 99.7 4.1 9.5e-29 99.1 0.5 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_S14 PF00253.16 CCF52478.1 - 7.3e-20 70.1 5.0 8e-20 69.9 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 CCF52478.1 - 1.2 9.2 4.9 4.5 7.4 0.4 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Aconitase PF00330.15 CCF52479.1 - 5.7e-176 585.5 0.1 1.2e-175 584.4 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCF52479.1 - 1.1e-43 148.5 0.0 2.3e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CCF52479.1 - 0.066 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MFS_1 PF07690.11 CCF52481.1 - 1.7e-27 96.0 42.5 2.7e-23 82.2 14.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF52481.1 - 8.9e-22 77.2 20.4 9e-21 73.9 14.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3716 PF12511.3 CCF52482.1 - 0.034 13.7 6.1 0.068 12.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) RhoGAP PF00620.22 CCF52484.1 - 4e-36 123.9 0.0 6.3e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 CCF52484.1 - 0.0065 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RNA_pol_Rbc25 PF08292.7 CCF52485.1 - 1.1e-39 135.4 0.0 1.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CCF52485.1 - 3.3e-18 65.5 0.0 6.6e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Bac_surface_Ag PF01103.18 CCF52486.1 - 8e-34 117.5 0.0 2.9e-32 112.4 0.0 2.1 1 1 0 1 1 1 1 Surface antigen PC_rep PF01851.17 CCF52487.1 - 5.5e-20 70.3 14.5 0.00021 21.3 0.1 8.5 8 0 0 8 8 8 5 Proteasome/cyclosome repeat Cation_efflux PF01545.16 CCF52488.1 - 3.6e-75 252.6 12.7 1.5e-74 250.6 8.8 1.7 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 CCF52488.1 - 1 8.2 24.5 15 4.4 17.0 2.2 1 1 0 1 1 1 0 ZIP Zinc transporter VirB3 PF05101.8 CCF52488.1 - 7 6.7 8.5 1 9.4 1.1 2.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Dynamin_N PF00350.18 CCF52489.1 - 8.4e-42 142.8 0.0 1.5e-41 142.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 CCF52489.1 - 1.6e-05 23.8 0.3 0.0024 16.6 0.1 2.8 2 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 CCF52489.1 - 0.0035 17.2 0.0 0.021 14.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCF52489.1 - 0.011 16.1 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein dUTPase PF00692.14 CCF52490.1 - 1.6e-42 144.0 0.0 2.1e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase Vps8 PF12816.2 CCF52491.1 - 3.3e-52 176.6 0.0 1.3e-50 171.4 0.0 2.9 2 1 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 UCH PF00443.24 CCF52493.1 - 4.6e-42 143.9 0.0 8.2e-42 143.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCF52493.1 - 2.5e-21 74.8 3.1 4.1e-18 64.5 0.5 3.2 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.1 CCF52493.1 - 8.8e-11 41.7 0.0 0.0008 18.9 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Focal_AT PF03623.8 CCF52493.1 - 0.017 14.5 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region Occludin_ELL PF07303.8 CCF52493.1 - 0.33 11.7 1.0 16 6.3 0.0 2.9 3 0 0 3 3 3 0 Occludin homology domain BAR PF03114.13 CCF52493.1 - 0.34 10.3 2.9 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 BAR domain Adaptin_N PF01602.15 CCF52494.1 - 3e-06 25.8 0.2 0.002 16.5 0.0 4.4 4 1 1 5 5 5 1 Adaptin N terminal region Cnd1 PF12717.2 CCF52494.1 - 0.0014 18.5 0.0 9.6 6.0 0.0 4.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CCF52494.1 - 0.002 17.8 1.8 0.17 11.7 0.1 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CCF52494.1 - 0.0043 17.0 26.6 0.11 12.6 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 CCF52494.1 - 3.7 8.1 32.3 0.5 10.9 0.1 9.3 7 2 3 10 10 10 0 HEAT-like repeat THUMP PF02926.12 CCF52495.1 - 2.1e-11 43.8 0.2 5.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 THUMP domain DGCR6 PF07324.6 CCF52496.1 - 0.00021 20.8 2.2 0.00067 19.1 1.1 1.8 1 1 1 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 CCF52496.1 - 0.00024 20.9 4.0 0.0099 15.7 0.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2458) Peptidase_U32 PF01136.14 CCF52496.1 - 0.076 11.9 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family U32 Apc15p PF05841.6 CCF52496.1 - 1.1 10.0 6.8 1.8 9.2 0.7 2.5 2 1 0 2 2 2 0 Apc15p protein Aminotran_3 PF00202.16 CCF52497.1 - 8.2e-37 126.8 0.0 7.6e-17 61.1 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 CCF52497.1 - 1.6e-21 76.8 0.0 3.3e-21 75.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Vps39_1 PF10366.4 CCF52499.1 - 2.4e-30 104.7 0.0 1.3e-29 102.4 0.0 2.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCF52499.1 - 2.7e-29 101.5 0.9 6e-29 100.4 0.2 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CCF52499.1 - 2.6e-13 50.0 0.0 5.3e-05 22.7 0.0 3.4 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 CCF52499.1 - 3.1e-08 33.3 0.1 0.0023 17.5 0.0 3.3 2 1 0 2 2 2 2 Region in Clathrin and VPS TPR_12 PF13424.1 CCF52499.1 - 0.059 13.3 0.3 4.7 7.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CCF52499.1 - 0.12 12.5 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Dus PF01207.12 CCF52500.1 - 1.9e-39 135.3 0.1 2.9e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyridox_oxase_2 PF12766.2 CCF52500.1 - 3.3e-25 88.2 0.0 6.7e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase His_Phos_1 PF00300.17 CCF52501.1 - 1.9e-21 76.7 0.0 3.1e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AARP2CN PF08142.7 CCF52502.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AARP2CN (NUC121) domain NIR_SIR PF01077.17 CCF52503.1 - 4.2e-43 146.4 0.0 3.4e-39 133.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CCF52503.1 - 1.2e-28 98.5 0.0 1.9e-15 56.2 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CCF52503.1 - 6.3e-28 97.5 0.0 1.5e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 CCF52503.1 - 2.9e-09 36.7 0.5 1.1e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg HAD_2 PF13419.1 CCF52504.1 - 1.6e-14 54.5 0.0 4.4e-14 53.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCF52504.1 - 9.6e-13 49.0 0.0 1.6e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF52504.1 - 1.5e-09 37.3 0.0 2.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCF52504.1 - 0.06 13.5 0.0 0.091 12.9 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L13e PF01294.13 CCF52505.1 - 7.2e-66 221.0 9.2 9.5e-66 220.6 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Herpes_US12 PF05363.7 CCF52505.1 - 0.39 11.2 3.4 3 8.4 0.2 2.3 2 0 0 2 2 2 0 Herpesvirus US12 family DUF1279 PF06916.8 CCF52508.1 - 6.6e-22 77.6 0.0 1.3e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Trypan_PARP PF05887.6 CCF52508.1 - 0.83 9.4 4.7 2 8.2 0.9 2.5 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) DUF4448 PF14610.1 CCF52509.1 - 0.043 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Plasmodium_Vir PF05795.6 CCF52509.1 - 1.5 7.9 3.0 3.2 6.8 2.2 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF936 PF06075.7 CCF52509.1 - 2.3 7.0 15.8 2.9 6.7 11.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) TRAM_LAG1_CLN8 PF03798.11 CCF52510.1 - 1.3e-28 99.8 27.4 1.3e-28 99.8 19.0 2.4 3 0 0 3 3 3 1 TLC domain TRAM1 PF08390.6 CCF52510.1 - 5.8e-15 54.5 0.0 5.8e-15 54.5 0.0 2.3 2 1 0 2 2 2 1 TRAM1-like protein Sec16 PF12932.2 CCF52511.1 - 0.045 13.7 0.5 0.79 9.7 0.1 2.2 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region FAM209 PF15206.1 CCF52512.1 - 0.11 12.2 0.8 0.91 9.3 0.1 2.6 2 0 0 2 2 2 0 FAM209 family Frag1 PF10277.4 CCF52513.1 - 1.4e-35 122.7 6.3 1.4e-35 122.7 4.4 2.2 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family PUF PF00806.14 CCF52515.1 - 4.1e-14 51.1 0.0 3.1e-05 23.1 0.0 6.5 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat HAUS6_N PF14661.1 CCF52515.1 - 0.037 13.3 5.5 3.2 7.0 2.3 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PapD-like PF14874.1 CCF52518.1 - 7.7e-09 35.4 0.1 0.2 11.5 0.0 5.2 5 0 0 5 5 5 4 Flagellar-associated PapD-like CAMSAP_CH PF11971.3 CCF52518.1 - 0.025 14.1 0.0 1.5 8.4 0.0 2.8 2 0 0 2 2 2 0 CAMSAP CH domain DUF1090 PF06476.7 CCF52518.1 - 0.063 12.9 1.5 0.17 11.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Ctf8 PF09696.5 CCF52519.1 - 9.7e-19 67.3 1.6 8.7e-11 41.6 0.0 2.5 2 1 0 2 2 2 2 Ctf8 ANAPC15 PF15243.1 CCF52519.1 - 0.12 12.4 4.3 0.23 11.5 3.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Urb2 PF10441.4 CCF52520.1 - 2.5e-38 131.9 0.5 2.5e-38 131.9 0.3 4.8 5 1 0 5 5 5 1 Urb2/Npa2 family Ribosomal_L36 PF00444.13 CCF52521.1 - 1.7e-22 79.1 7.7 2.5e-22 78.5 5.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Gly-zipper_OmpA PF13436.1 CCF52522.1 - 3.3 7.3 11.6 3.7 7.2 0.6 2.9 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Atg14 PF10186.4 CCF52524.1 - 1.3e-20 73.5 0.7 2.5e-20 72.6 0.5 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_32 PF13654.1 CCF52524.1 - 0.29 9.7 6.9 0.45 9.1 4.8 1.2 1 0 0 1 1 1 0 AAA domain NTP_transferase PF00483.18 CCF52525.1 - 3.3e-46 157.5 0.0 4.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCF52525.1 - 1.7e-07 31.4 0.3 4e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 CCF52525.1 - 6.1e-06 25.9 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 CCF52525.1 - 0.031 13.7 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CoA_transf_3 PF02515.12 CCF52525.1 - 0.058 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 CoA-transferase family III DUF2205 PF10224.4 CCF52525.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) PAPS_reduct PF01507.14 CCF52527.1 - 6.5e-37 127.0 0.0 9.7e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Amidohydro_1 PF01979.15 CCF52528.1 - 2.1e-36 126.2 0.0 1.3e-17 64.4 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.6 CCF52528.1 - 0.00025 20.4 0.1 0.04 13.1 0.1 3.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCF52528.1 - 0.0017 18.1 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase DUF3395 PF11875.3 CCF52529.1 - 1.9e-34 118.4 0.0 4e-34 117.4 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CCF52529.1 - 5.7e-23 80.4 0.6 1.1e-22 79.5 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain SOG2 PF10428.4 CCF52529.1 - 1.4 7.4 12.9 2.1 6.8 8.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Med5 PF08689.5 CCF52530.1 - 2.2e-34 118.3 5.4 1.7e-31 108.8 0.0 2.6 3 0 0 3 3 3 2 Mediator complex subunit Med5 Aa_trans PF01490.13 CCF52531.1 - 7.9e-80 268.3 32.1 9.5e-80 268.0 22.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Redoxin PF08534.5 CCF52532.1 - 4.7e-35 120.2 0.0 5.2e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCF52532.1 - 2.3e-09 36.9 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Yippee-Mis18 PF03226.9 CCF52533.1 - 2.3e-21 75.6 0.0 3.9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PA26 PF04636.8 CCF52533.1 - 0.19 10.3 0.4 0.27 9.8 0.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) API5 PF05918.6 CCF52533.1 - 1.2 7.5 6.2 1.8 6.9 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DCP1 PF06058.8 CCF52534.1 - 8.6e-26 90.3 0.0 1.3e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family HLH PF00010.21 CCF52535.1 - 1.3e-18 66.3 0.0 3.5e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med15 PF09606.5 CCF52535.1 - 0.00012 20.5 54.4 0.00012 20.5 37.7 2.2 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CCF52535.1 - 3 5.9 59.6 0.1 10.8 28.9 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Podoplanin PF05808.6 CCF52535.1 - 6.7 6.2 10.3 10 5.6 1.5 2.6 2 0 0 2 2 2 0 Podoplanin TIMELESS PF04821.9 CCF52536.1 - 2.1e-32 112.4 0.1 2.1e-32 112.4 0.1 3.2 3 1 0 3 3 3 1 Timeless protein NUDIX PF00293.23 CCF52537.1 - 1.9e-12 47.0 0.0 4.1e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Med8 PF10232.4 CCF52537.1 - 0.07 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 RPAP2_Rtr1 PF04181.8 CCF52538.1 - 1.7e-15 56.8 0.0 3.4e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family DAP3 PF10236.4 CCF52538.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 BTB PF00651.26 CCF52539.1 - 6.8e-10 38.9 0.6 0.00014 21.7 0.1 2.9 3 0 0 3 3 3 2 BTB/POZ domain SSF PF00474.12 CCF52540.1 - 1.1e-14 53.9 19.5 1.1e-14 53.9 13.5 1.9 2 1 0 2 2 2 1 Sodium:solute symporter family Arrestin_N PF00339.24 CCF52541.1 - 3.8e-05 23.5 3.2 4.7e-05 23.2 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCF52541.1 - 0.00069 19.7 0.0 0.039 14.0 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Borrelia_P83 PF05262.6 CCF52541.1 - 0.019 13.2 22.5 0.0056 15.0 12.4 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Spo0M PF07070.6 CCF52541.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Vps26 PF03643.10 CCF52541.1 - 0.71 8.6 0.0 2.8 6.6 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 HABP4_PAI-RBP1 PF04774.10 CCF52542.1 - 2.5e-09 37.5 8.3 2.5e-09 37.5 5.8 3.3 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family DUF2894 PF11445.3 CCF52542.1 - 1.6 8.9 8.1 2.9 8.0 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Ribosomal_S3_C PF00189.15 CCF52543.1 - 9.3e-17 61.0 0.1 1.7e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCF52543.1 - 2.7e-13 49.2 0.0 4.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 CCF52543.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Memo PF01875.12 CCF52544.1 - 1e-75 254.2 0.0 1.9e-75 253.3 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein SWIB PF02201.13 CCF52545.1 - 1.2e-16 60.0 0.0 2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain ACBP PF00887.14 CCF52547.1 - 1.7e-34 117.3 0.3 2.4e-34 116.8 0.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein HEAT PF02985.17 CCF52548.1 - 8.1e-42 137.5 22.0 0.0014 18.4 0.0 13.6 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 CCF52548.1 - 1.9e-34 117.7 6.8 4.6e-09 36.4 0.0 6.7 2 1 5 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CCF52548.1 - 4.5e-12 46.1 0.6 0.0094 16.3 0.0 6.8 4 2 4 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCF52548.1 - 1.9e-09 37.7 16.8 0.58 10.7 0.0 9.0 8 2 1 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 CCF52548.1 - 2.3e-08 32.8 5.6 0.027 12.7 0.0 5.0 2 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 CCF52548.1 - 0.00049 19.5 2.3 0.48 9.7 0.0 4.5 2 2 3 5 5 5 1 CLASP N terminal Arm PF00514.18 CCF52548.1 - 0.0022 17.7 0.6 6.9 6.6 0.0 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 CCF52548.1 - 0.0088 16.4 0.5 18 6.1 0.0 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat V-ATPase_H_N PF03224.9 CCF52548.1 - 0.024 13.7 0.7 0.29 10.2 0.5 2.7 1 1 0 1 1 1 0 V-ATPase subunit H DUF2435 PF10363.4 CCF52548.1 - 0.046 13.6 2.4 4.4 7.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Ada3 PF10198.4 CCF52549.1 - 1.6e-38 131.3 1.6 1.8e-38 131.2 0.1 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF3521 PF12035.3 CCF52549.1 - 0.015 15.1 0.3 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) Nucleo_P87 PF07267.6 CCF52549.1 - 1.2 7.6 4.2 2.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Oxysterol_BP PF01237.13 CCF52550.1 - 3.6e-66 223.0 0.0 7.3e-54 182.5 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein RNase_P_pop3 PF08228.6 CCF52551.1 - 0.00057 19.7 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 RNase P subunit Pop3 Gtr1_RagA PF04670.7 CCF52552.1 - 2.6e-27 95.4 1.5 3.3e-15 55.8 1.3 4.0 3 1 0 3 3 3 3 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF52552.1 - 0.032 14.7 0.0 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 CCF52552.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 CCF52552.1 - 0.054 12.7 0.1 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 CCF52552.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 CCF52552.1 - 0.084 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain C1-set PF07654.10 CCF52552.1 - 0.097 12.6 0.1 0.41 10.6 0.0 2.1 3 0 0 3 3 3 0 Immunoglobulin C1-set domain GTP_EFTU PF00009.22 CCF52552.1 - 0.15 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Pex24p PF06398.6 CCF52553.1 - 4e-25 88.3 0.5 4e-25 88.3 0.3 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin Sin_N PF04801.8 CCF52554.1 - 2.1e-26 92.7 0.1 1.9e-24 86.3 0.0 2.3 2 1 0 2 2 2 2 Sin-like protein conserved region NDK PF00334.14 CCF52555.1 - 9.5e-50 167.8 0.0 1.2e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase LSM PF01423.17 CCF52556.1 - 3.5e-15 55.2 1.5 4.7e-15 54.8 1.1 1.2 1 0 0 1 1 1 1 LSM domain UQ_con PF00179.21 CCF52557.1 - 1.9e-36 124.5 0.1 2.6e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LETM1 PF07766.8 CCF52558.1 - 4.4e-26 91.5 0.8 9.4e-13 47.8 0.0 2.4 1 1 1 2 2 2 2 LETM1-like protein Acyl_transf_1 PF00698.16 CCF52559.1 - 6.6e-55 186.6 0.0 3.8e-54 184.1 0.0 2.3 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CCF52559.1 - 2.4e-28 98.0 0.2 3.1e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.21 CCF52559.1 - 2.6e-27 95.9 0.5 8.1e-27 94.2 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF1729 PF08354.5 CCF52559.1 - 1.8e-25 88.4 0.1 4.6e-25 87.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) adh_short_C2 PF13561.1 CCF52559.1 - 1e-19 71.3 0.0 3.3e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 CCF52559.1 - 1.2e-15 57.4 0.6 1.2e-15 57.4 0.4 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 CCF52559.1 - 4.1e-12 45.9 0.0 1.3e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Thiolase_N PF00108.18 CCF52559.1 - 0.0015 17.6 0.0 0.0033 16.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain zf-RING_2 PF13639.1 CCF52560.1 - 1.8e-12 46.8 8.1 2.9e-12 46.1 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCF52560.1 - 2.5e-09 37.1 3.0 4.5e-09 36.2 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCF52560.1 - 8e-09 35.3 3.1 1.9e-08 34.2 2.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF52560.1 - 1.7e-07 30.7 5.7 3e-07 29.9 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52560.1 - 9.9e-07 28.3 4.8 1.7e-06 27.6 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCF52560.1 - 5e-05 22.8 5.8 0.00013 21.5 4.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF52560.1 - 0.00021 21.0 2.1 0.00038 20.2 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CCF52560.1 - 0.0015 18.2 4.7 0.0015 18.2 3.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.6 CCF52560.1 - 0.011 15.6 1.2 0.024 14.6 0.8 1.5 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.2 CCF52560.1 - 0.055 13.5 4.3 0.13 12.3 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 CCF52560.1 - 0.058 13.2 0.4 0.058 13.2 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CCF52560.1 - 0.1 12.5 5.3 0.6 10.1 3.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCF52560.1 - 0.14 11.8 5.5 0.46 10.1 3.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CCF52560.1 - 0.33 10.4 5.2 0.66 9.5 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CCF52560.1 - 6.5 6.3 7.9 1.3 8.6 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 ATG22 PF11700.3 CCF52562.1 - 4e-128 427.9 22.5 4.6e-128 427.7 15.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CCF52562.1 - 3e-11 42.6 26.9 6.6e-05 21.7 5.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.11 CCF52562.1 - 0.089 11.4 11.4 0.016 13.9 4.1 2.0 2 0 0 2 2 2 0 BT1 family Pal1 PF08316.6 CCF52563.1 - 3.2e-14 53.5 0.6 3.2e-14 53.5 0.4 2.6 2 0 0 2 2 2 1 Pal1 cell morphology protein DUF3516 PF12029.3 CCF52565.1 - 0.087 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) LRR_6 PF13516.1 CCF52566.1 - 1.9e-11 42.7 22.0 0.48 10.6 0.0 10.0 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.2 CCF52566.1 - 1.1e-07 31.3 21.7 0.00015 21.3 0.4 6.7 4 1 4 8 8 8 5 Leucine Rich repeats (2 copies) GAT PF03127.9 CCF52566.1 - 0.00032 20.6 0.0 0.001 18.9 0.0 1.9 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.28 CCF52566.1 - 0.00051 19.6 15.5 4.5 7.6 0.0 8.2 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.1 CCF52566.1 - 0.0011 18.6 13.3 0.013 15.2 0.3 5.2 4 1 1 5 5 5 2 Leucine rich repeat RRM_5 PF13893.1 CCF52567.1 - 4.5e-07 29.6 0.0 1.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF52567.1 - 5e-07 29.2 0.0 1.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52567.1 - 0.0014 18.5 0.2 0.0071 16.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCF52567.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 CCF52567.1 - 0.014 15.0 5.5 0.028 14.0 3.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ASFV_J13L PF05568.6 CCF52567.1 - 1.4 8.4 5.9 0.29 10.6 1.5 1.7 2 0 0 2 2 2 0 African swine fever virus J13L protein GST_C_2 PF13410.1 CCF52568.1 - 1.4e-12 47.2 0.0 3.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCF52568.1 - 2.4e-07 30.8 0.0 4.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF52568.1 - 9.9e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCF52568.1 - 0.0096 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCF52568.1 - 0.038 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATXN-1_C PF12547.3 CCF52568.1 - 0.3 11.0 5.8 0.22 11.4 0.2 2.7 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator Methyltransf_16 PF10294.4 CCF52569.1 - 2.2e-05 23.9 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 CCF52569.1 - 0.0098 15.4 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain DUF4479 PF14794.1 CCF52569.1 - 0.068 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) ILVD_EDD PF00920.16 CCF52570.1 - 4.3e-203 675.4 1.3 4.9e-203 675.2 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family DPBB_1 PF03330.13 CCF52571.1 - 1.8e-09 37.4 0.1 3.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Spt5_N PF11942.3 CCF52571.1 - 0.023 15.2 8.4 0.034 14.7 5.8 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF1777 PF08648.7 CCF52571.1 - 0.032 13.9 11.8 0.042 13.5 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) LZ_Tnp_IS66 PF13007.2 CCF52571.1 - 0.037 14.6 2.1 0.062 13.9 1.5 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain POX PF07526.6 CCF52571.1 - 0.08 13.1 3.7 0.15 12.3 2.6 1.5 1 0 0 1 1 1 0 Associated with HOX Sporozoite_P67 PF05642.6 CCF52571.1 - 0.11 10.2 2.7 0.12 10.2 1.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-RING_6 PF14835.1 CCF52571.1 - 0.44 10.3 2.7 0.8 9.5 1.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TFIIF_alpha PF05793.7 CCF52571.1 - 0.82 7.9 12.5 1 7.6 8.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CCF52571.1 - 0.99 7.3 12.4 1.2 7.0 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 CCF52571.1 - 1.1 7.8 4.5 1.3 7.6 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zip PF02535.17 CCF52571.1 - 1.7 7.5 7.8 2.1 7.2 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.4 CCF52571.1 - 3.5 6.3 12.2 4.5 6.0 8.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI-PLC-X PF00388.14 CCF52572.1 - 1.1e-55 187.0 0.0 2e-55 186.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCF52572.1 - 3.4e-39 133.4 0.0 6.7e-39 132.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.1 CCF52572.1 - 1.2e-06 28.4 0.1 4.5e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_like PF09279.6 CCF52572.1 - 8.6e-06 25.6 0.1 3.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CCF52572.1 - 0.00065 18.8 0.8 0.31 10.4 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CCF52572.1 - 0.0022 17.7 2.1 0.15 12.0 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain C2 PF00168.25 CCF52572.1 - 0.0039 17.0 0.1 0.63 9.9 0.1 3.0 2 1 0 2 2 2 1 C2 domain EF-hand_10 PF14788.1 CCF52572.1 - 0.028 14.0 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 EF hand zf-C2H2_jaz PF12171.3 CCF52573.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Oxysterol_BP PF01237.13 CCF52573.1 - 0.38 9.1 8.7 0.46 8.9 6.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Daxx PF03344.10 CCF52573.1 - 0.58 8.5 34.2 0.79 8.1 23.7 1.2 1 0 0 1 1 1 0 Daxx Family AKAP95 PF04988.7 CCF52573.1 - 5.4 6.7 9.9 0.077 12.7 1.1 2.0 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF2981 PF11200.3 CCF52573.1 - 7.2 5.5 10.3 3 6.8 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) Acyl-CoA_dh_2 PF08028.6 CCF52574.1 - 4.4e-16 59.3 0.6 7.4e-16 58.6 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCF52574.1 - 6.8e-09 36.2 0.4 2.6e-08 34.4 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 CCF52574.1 - 0.0081 16.2 0.7 0.037 14.1 0.5 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ADH_N PF08240.7 CCF52575.1 - 5.6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF52575.1 - 0.0082 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF52575.1 - 0.13 13.1 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CENP-B_dimeris PF09026.5 CCF52576.1 - 0.011 16.0 0.2 0.025 14.7 0.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HD PF01966.17 CCF52576.1 - 0.033 14.1 0.1 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 HD domain NIF PF03031.13 CCF52577.1 - 4.8e-24 84.8 0.2 2e-23 82.8 0.0 2.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CCF52577.1 - 0.00041 20.6 0.1 0.0032 17.7 0.0 2.3 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HTH_3 PF01381.17 CCF52577.1 - 0.12 12.1 0.2 22 4.9 0.0 4.1 5 0 0 5 5 5 0 Helix-turn-helix WD40 PF00400.27 CCF52578.1 - 9e-47 155.3 27.1 5.7e-09 35.5 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 CCF52578.1 - 1.2e-08 34.4 1.9 3e-08 33.2 1.3 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 CCF52578.1 - 0.00014 20.1 2.0 0.19 9.7 0.4 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCF52578.1 - 0.011 15.2 0.5 0.36 10.2 0.1 2.7 2 0 0 2 2 2 0 PQQ-like domain F-box PF00646.28 CCF52578.1 - 0.022 14.4 1.9 0.061 13.0 1.3 1.8 1 0 0 1 1 1 0 F-box domain Herpes_gE PF02480.11 CCF52579.1 - 0.074 11.2 0.1 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 CCF52579.1 - 0.19 11.2 0.1 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein MT-A70 PF05063.9 CCF52581.1 - 5.1e-49 166.2 0.0 2.9e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 CCF52581.1 - 0.0099 15.8 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 CCF52582.1 - 1.7e-17 63.8 0.3 1e-16 61.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCF52582.1 - 2.4e-08 33.8 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF52582.1 - 3.1e-05 23.8 0.0 5.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2018 PF09442.5 CCF52582.1 - 0.044 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) NAD_binding_10 PF13460.1 CCF52582.1 - 0.14 12.1 2.1 5.8 6.8 1.4 2.4 1 1 0 1 1 1 0 NADH(P)-binding LRR_4 PF12799.2 CCF52583.1 - 9.1e-25 85.8 15.4 3.1e-06 26.6 0.3 5.6 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF52583.1 - 7.1e-19 67.3 18.9 1.9e-10 40.3 4.0 5.5 4 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CCF52583.1 - 3.5e-12 44.5 19.3 0.07 13.1 0.0 8.2 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 CCF52583.1 - 4.4e-09 35.0 20.0 0.94 9.9 0.0 8.4 8 0 0 8 8 8 5 Leucine rich repeat LRR_6 PF13516.1 CCF52583.1 - 3.1e-08 32.8 18.6 0.16 12.1 0.0 7.8 6 1 1 7 7 7 2 Leucine Rich repeat zf-CCCH PF00642.19 CCF52583.1 - 0.0001 21.8 6.5 0.0014 18.2 0.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_3 PF07725.7 CCF52583.1 - 0.0086 15.7 0.4 0.0086 15.7 0.3 2.7 3 0 0 3 3 3 1 Leucine Rich Repeat DUF3275 PF11679.3 CCF52583.1 - 0.4 10.2 3.6 0.43 10.1 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) MAGE PF01454.14 CCF52584.1 - 3.4e-27 95.0 0.0 9.1e-23 80.6 0.0 2.9 2 1 0 2 2 2 2 MAGE family TMP-TENI PF02581.12 CCF52584.1 - 0.061 12.4 0.1 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Mg_trans_NIPA PF05653.9 CCF52585.1 - 4.5e-110 367.3 15.5 5.7e-110 366.9 10.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CCF52585.1 - 7.8e-08 32.5 0.8 7.8e-08 32.5 0.6 3.2 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CCF52585.1 - 0.00019 21.4 4.0 0.00019 21.4 2.8 3.8 3 1 1 4 4 4 1 EamA-like transporter family DUF2937 PF11157.3 CCF52585.1 - 0.04 13.2 0.4 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) RRM_1 PF00076.17 CCF52586.1 - 4.9e-25 86.9 0.0 3.8e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52586.1 - 1e-13 51.0 0.0 2.6e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF52586.1 - 0.04 13.7 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PEMT PF04191.8 CCF52587.1 - 1.6e-54 182.5 9.0 2.7e-32 111.0 1.0 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase NPR3 PF03666.8 CCF52588.1 - 7.4e-114 380.7 0.0 7.4e-114 380.7 0.0 3.2 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 CCF52588.1 - 0.016 13.8 0.8 6.4 5.3 0.0 3.1 3 0 0 3 3 3 0 Nitrogen permease regulator 2 DUF106 PF01956.11 CCF52589.1 - 7.9e-58 194.7 0.2 9.5e-58 194.4 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Bot1p PF12298.3 CCF52590.1 - 1.1e-28 100.3 0.1 2e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 CCF52590.1 - 0.00033 20.6 0.0 0.00078 19.4 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Claudin_2 PF13903.1 CCF52592.1 - 0.0012 18.5 2.6 0.0012 18.5 1.8 2.1 1 1 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF1469 PF07332.6 CCF52592.1 - 0.21 11.3 8.4 0.64 9.7 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2818 PF10993.3 CCF52592.1 - 0.45 11.0 5.6 0.12 12.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) MBOAT PF03062.14 CCF52593.1 - 2.3e-46 158.4 16.4 2.3e-46 158.4 11.4 1.6 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Clat_adaptor_s PF01217.15 CCF52594.1 - 7.1e-55 184.6 1.0 8.4e-55 184.3 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SCP2 PF02036.12 CCF52595.1 - 7.1e-25 87.2 1.8 8.2e-25 87.0 1.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCF52595.1 - 4.8e-05 23.3 0.5 5.5e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Aldo_ket_red PF00248.16 CCF52597.1 - 2.1e-10 39.9 0.2 0.002 17.0 0.0 3.0 2 1 1 3 3 3 3 Aldo/keto reductase family TGS PF02824.16 CCF52598.1 - 3.8e-21 74.6 0.0 6.8e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCF52598.1 - 3.2e-18 65.7 0.2 1.1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF52598.1 - 3.9e-09 35.9 0.2 9.8e-09 34.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCF52598.1 - 0.0071 16.1 0.4 0.26 11.0 0.0 2.5 1 1 1 2 2 2 1 Dynamin family ArgK PF03308.11 CCF52598.1 - 0.091 11.5 2.5 0.091 11.5 0.4 2.0 2 1 0 2 2 2 0 ArgK protein Cyt-b5 PF00173.23 CCF52599.1 - 2.2e-09 36.9 0.1 2.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PNPOx_C PF10590.4 CCF52600.1 - 1.2e-21 75.8 0.4 2.1e-21 75.1 0.3 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CCF52600.1 - 9.2e-17 60.8 0.0 1.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 CCF52600.1 - 0.003 17.8 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Tetraspannin PF00335.15 CCF52601.1 - 0.0033 16.7 10.6 0.0035 16.6 6.4 1.6 1 1 1 2 2 2 1 Tetraspanin family DUF4415 PF14384.1 CCF52601.1 - 0.036 14.2 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) Tic20 PF09685.5 CCF52601.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 Tic20-like protein DUF4234 PF14018.1 CCF52601.1 - 6.8 6.5 8.2 1.8 8.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) Amidohydro_3 PF07969.6 CCF52602.1 - 7.8e-58 196.6 0.2 9.3e-58 196.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 CCF52602.1 - 6.5e-11 42.4 0.0 5.4e-07 29.5 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CCF52602.1 - 3.8e-10 39.4 0.0 2.2e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 CCF52602.1 - 5.2e-06 26.6 6.6 0.0037 17.3 0.0 2.9 2 2 0 2 2 2 2 Amidohydrolase SpoVS PF04232.7 CCF52602.1 - 0.11 12.0 0.1 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) EAP30 PF04157.11 CCF52604.1 - 1.9e-53 180.8 0.0 2.6e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CCF52604.1 - 1.1e-30 105.2 0.0 1.9e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CCF52604.1 - 5.7e-06 25.3 11.1 0.0023 16.9 1.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AalphaY_MDB PF04611.7 CCF52604.1 - 0.0082 16.0 0.9 0.022 14.6 0.6 1.7 1 0 0 1 1 1 1 Mating type protein A alpha Y mating type dependent binding region DZR PF12773.2 CCF52604.1 - 0.018 14.8 3.2 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF1024 PF06260.7 CCF52604.1 - 0.089 12.9 0.2 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Nif11 PF07862.6 CCF52604.1 - 0.11 12.4 1.8 0.25 11.3 1.2 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function PPP4R2 PF09184.6 CCF52604.1 - 0.12 11.8 0.5 0.28 10.7 0.4 1.6 1 0 0 1 1 1 0 PPP4R2 GRAM PF02893.15 CCF52604.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Cript PF10235.4 CCF52604.1 - 0.41 11.0 4.0 1.9 8.8 0.0 2.7 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT CLU PF13236.1 CCF52605.1 - 7.1e-76 254.4 0.0 1.1e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CCF52605.1 - 3.2e-43 147.6 0.0 9.5e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CCF52605.1 - 1.2e-17 63.6 3.7 1.8e-08 34.1 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCF52605.1 - 4.8e-12 45.3 7.5 0.00086 19.1 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.1 CCF52605.1 - 5.5e-05 23.2 0.1 0.00029 20.9 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term GETHR PF05671.6 CCF52605.1 - 0.035 13.2 25.9 0.15 11.2 9.7 2.5 1 1 1 2 2 2 0 GETHR pentapeptide repeat (5 copies) DUF727 PF05303.7 CCF52605.1 - 0.16 11.7 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF727) HMG-CoA_red PF00368.13 CCF52606.1 - 5.1e-160 532.1 5.3 7.2e-160 531.6 3.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 CCF52606.1 - 9.3e-17 60.9 4.0 5.6e-08 32.3 0.1 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCF52606.1 - 2e-07 29.3 5.4 0.00046 18.2 0.0 3.0 3 0 0 3 3 3 2 Patched family PITH PF06201.8 CCF52607.1 - 8.3e-37 126.3 0.1 1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain C2 PF00168.25 CCF52608.1 - 1.2e-23 82.6 0.0 2.2e-17 62.6 0.0 2.7 2 0 0 2 2 2 2 C2 domain Sigma_1_2 PF03084.9 CCF52608.1 - 0.11 11.1 0.2 0.17 10.4 0.2 1.2 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family A2M_N PF01835.14 CCF52609.1 - 0.04 14.1 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 MG2 domain GPI-anchored PF10342.4 CCF52609.1 - 0.045 14.2 0.1 0.27 11.7 0.0 2.1 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_L38e PF01781.13 CCF52610.1 - 3.9e-33 113.0 1.3 4.4e-33 112.8 0.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family E6 PF00518.12 CCF52610.1 - 0.012 15.8 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 0 Early Protein (E6) Ribosomal_S11 PF00411.14 CCF52611.1 - 2.6e-40 137.0 0.7 3.2e-40 136.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 CCF52611.1 - 0.012 14.5 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 CCF52611.1 - 0.056 13.3 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF814) EVE PF01878.13 CCF52612.1 - 4.2e-43 146.7 0.7 7.2e-43 146.0 0.0 1.7 2 0 0 2 2 2 1 EVE domain TLP-20 PF06088.6 CCF52612.1 - 0.58 9.8 4.6 0.81 9.3 3.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TP53IP5 PF15331.1 CCF52612.1 - 1.1 9.1 8.0 3.3 7.5 5.9 1.5 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 GvpO PF05800.6 CCF52612.1 - 1.7 8.5 4.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO Mpv17_PMP22 PF04117.7 CCF52613.1 - 6.8e-24 83.2 0.3 1.1e-23 82.5 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BCIP PF13862.1 CCF52616.1 - 5.3e-58 195.7 0.0 6.7e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Peptidase_S8 PF00082.17 CCF52619.1 - 6.5e-52 176.4 4.6 1e-51 175.7 3.2 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 CCF52619.1 - 6.7e-17 61.9 0.5 1.1e-14 54.7 0.0 2.9 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 CCF52619.1 - 6.8e-09 35.3 0.0 1.9e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 CCF52619.1 - 0.00097 19.6 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribonuclease_T2 PF00445.13 CCF52620.1 - 2.3e-33 115.4 1.6 3.6e-33 114.7 1.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family MutS_V PF00488.16 CCF52621.1 - 1.3e-93 312.7 0.0 2e-93 312.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCF52621.1 - 2.4e-34 118.9 0.5 2.4e-34 118.9 0.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CCF52621.1 - 8.7e-19 67.9 0.0 2.9e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 CCF52621.1 - 1.6e-13 50.6 0.0 3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CCF52621.1 - 1.7e-13 50.5 1.6 2.5e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 MutS family domain IV DUF77 PF01910.12 CCF52622.1 - 3.4e-26 90.7 0.0 4.1e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 CCF52622.1 - 0.016 15.3 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family Mon1 PF03164.9 CCF52623.1 - 3.6e-77 259.7 0.1 7.7e-27 93.9 0.1 4.7 3 1 0 4 4 4 4 Trafficking protein Mon1 DUF913 PF06025.7 CCF52623.1 - 0.097 11.4 0.1 0.29 9.8 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mg_trans_NIPA PF05653.9 CCF52624.1 - 7.3e-29 100.6 6.3 3.1e-14 52.6 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF1771 PF08590.5 CCF52625.1 - 2.5e-24 85.0 7.7 3e-24 84.7 2.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 CCF52625.1 - 1e-13 51.2 0.3 2.3e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 Smr domain Peripla_BP_2 PF01497.13 CCF52625.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein SUI1 PF01253.17 CCF52626.1 - 1.2e-12 47.4 0.0 2.5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 CCF52626.1 - 0.012 15.4 0.2 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Transposon-encoded protein TnpV ArfGap PF01412.13 CCF52629.1 - 3.9e-41 139.4 0.1 3.9e-41 139.4 0.1 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf zf-DHHC PF01529.15 CCF52629.1 - 0.011 15.0 0.8 0.019 14.3 0.6 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase FimP PF09766.4 CCF52629.1 - 3.6 6.5 22.4 6.7 5.6 15.5 1.4 1 0 0 1 1 1 0 Fms-interacting protein G0-G1_switch_2 PF15103.1 CCF52629.1 - 6 7.1 7.9 15 5.8 5.5 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 ATAD4 PF15321.1 CCF52629.1 - 9.4 7.3 14.2 36 5.4 6.3 3.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DENN PF02141.16 CCF52630.1 - 3.5e-19 69.2 0.0 5.7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Methyltransf_16 PF10294.4 CCF52630.1 - 5.7e-12 45.4 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCF52630.1 - 0.003 18.1 0.0 0.012 16.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FlxA PF14282.1 CCF52630.1 - 0.0061 16.4 15.8 0.39 10.6 3.3 3.0 2 0 0 2 2 2 2 FlxA-like protein WXG100 PF06013.7 CCF52630.1 - 0.08 12.9 10.9 0.71 9.9 0.3 3.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG IFT57 PF10498.4 CCF52630.1 - 0.1 11.2 11.1 0.67 8.6 3.2 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 UPF0242 PF06785.6 CCF52630.1 - 0.32 9.6 5.4 0.51 8.9 3.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Syntaxin PF00804.20 CCF52630.1 - 0.34 11.0 16.1 0.36 11.0 0.5 3.6 3 0 0 3 3 3 0 Syntaxin Baculo_PEP_C PF04513.7 CCF52630.1 - 5 6.9 9.8 1.9 8.3 0.4 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mpp10 PF04006.7 CCF52631.1 - 2.6e-92 310.1 143.7 5.7e-84 282.6 38.5 3.3 1 1 0 3 3 3 3 Mpp10 protein Methyltransf_23 PF13489.1 CCF52632.1 - 1.8e-21 76.5 0.0 2.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF52632.1 - 7e-18 64.9 0.0 2.1e-17 63.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF52632.1 - 1.2e-13 50.8 0.0 3.3e-13 49.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF52632.1 - 4.4e-13 49.5 0.0 1.4e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52632.1 - 8.9e-12 45.5 0.0 1.5e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF52632.1 - 2.4e-07 31.0 0.0 4.6e-06 26.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF52632.1 - 1.6e-06 28.1 0.3 5.2e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCF52632.1 - 2.3e-05 23.2 0.0 3.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 CCF52632.1 - 5.4e-05 22.4 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 CCF52632.1 - 0.0002 20.5 0.0 0.00048 19.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CCF52632.1 - 0.002 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CCF52632.1 - 0.0036 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 CCF52632.1 - 0.015 14.7 0.0 0.076 12.3 0.0 1.9 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 CCF52632.1 - 0.069 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DcpS_C PF11969.3 CCF52633.1 - 3.3e-23 82.1 0.2 4.8e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCF52633.1 - 1.3e-10 41.6 3.7 9.1e-10 38.9 2.6 2.0 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 CCF52633.1 - 0.017 14.7 0.4 0.045 13.3 0.3 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Abhydrolase_6 PF12697.2 CCF52634.1 - 6.1e-20 72.0 0.0 8.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52634.1 - 3.6e-15 55.9 0.0 6e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCF52634.1 - 7.1e-08 32.2 0.0 5.6e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCF52634.1 - 9.1e-07 28.6 0.1 0.047 13.2 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CCF52634.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CCF52634.1 - 0.019 13.9 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 CCF52634.1 - 0.063 12.3 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 CCF52634.1 - 0.079 12.1 0.1 0.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family TruB_N PF01509.13 CCF52635.1 - 2.3e-38 131.6 0.0 1.6e-37 128.9 0.0 2.0 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) HTH_9 PF08221.6 CCF52636.1 - 1.5e-18 66.4 0.4 1.9e-07 30.8 0.0 4.9 5 0 0 5 5 5 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CCF52636.1 - 6.8e-15 55.2 0.5 8e-13 48.5 0.2 2.6 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 CCF52636.1 - 9.9e-07 28.2 0.2 3.7e-05 23.1 0.1 2.7 2 0 0 2 2 2 1 TFIIE alpha subunit DUF4078 PF13300.1 CCF52637.1 - 4.1e-11 42.8 14.6 4.1e-11 42.8 10.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) WD40 PF00400.27 CCF52638.1 - 1.1e-51 170.8 8.8 3.9e-12 45.5 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCF52638.1 - 0.0012 17.6 0.1 3.9 6.1 0.0 4.2 2 2 0 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 CCF52638.1 - 0.0062 14.8 0.0 0.01 14.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Nup160 PF11715.3 CCF52638.1 - 0.078 11.1 8.2 2.3 6.2 0.0 4.4 3 2 0 4 4 4 0 Nucleoporin Nup120/160 VID27 PF08553.5 CCF52638.1 - 0.09 10.9 0.0 0.21 9.7 0.0 1.5 2 0 0 2 2 2 0 VID27 cytoplasmic protein Ribonuclease_3 PF00636.21 CCF52639.1 - 7e-09 36.1 0.0 2.2e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCF52639.1 - 3.7e-07 30.1 0.0 0.066 13.1 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.20 CCF52639.1 - 8e-07 29.5 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF3774 PF12609.3 CCF52639.1 - 1.6 9.6 5.7 39 5.1 1.5 3.6 4 1 0 4 4 4 0 Wound-induced protein TFIIF_beta PF02270.10 CCF52640.1 - 9e-56 189.6 0.0 1.2e-54 186.0 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 CCF52640.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 IS66 C-terminal element TFIIF_alpha PF05793.7 CCF52640.1 - 4.4 5.5 16.9 4.5 5.5 0.2 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AA_permease_2 PF13520.1 CCF52641.1 - 2.4e-62 210.8 44.2 3.1e-62 210.4 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF52641.1 - 2.7e-24 85.3 38.3 3.4e-24 85.0 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 CCF52641.1 - 0.0048 16.6 4.1 0.015 15.0 0.0 3.5 2 0 0 2 2 2 1 Gram positive anchor HSF_DNA-bind PF00447.12 CCF52642.1 - 1.3e-31 108.8 0.0 2.4e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Chitin_synth_2 PF03142.10 CCF52643.1 - 1.3e-252 838.8 0.1 1.7e-252 838.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.23 CCF52643.1 - 1e-21 76.4 0.0 2.5e-15 56.0 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 CCF52643.1 - 4.5e-16 58.3 0.0 2.6e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 CCF52643.1 - 6.7e-14 52.2 0.0 6.2e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCF52643.1 - 1.1e-13 51.3 6.3 1.1e-13 51.3 4.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CCF52643.1 - 2.4e-06 27.3 0.0 0.0011 18.7 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCF52643.1 - 5.2e-06 25.8 0.0 2.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 RVT_2 PF07727.9 CCF52644.1 - 1.9e-38 131.8 0.1 2.5e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2416 PF10315.4 CCF52645.1 - 7.4e-12 45.4 1.7 1.4e-11 44.5 0.4 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2416) DUF3149 PF11346.3 CCF52646.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Aa_trans PF01490.13 CCF52647.1 - 1.1e-28 99.9 27.8 1.7e-28 99.2 19.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.22 CCF52649.1 - 7.8e-39 133.1 0.0 4.8e-23 81.9 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCF52649.1 - 4.4e-32 111.5 28.0 2.4e-19 69.8 9.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CCF52649.1 - 5e-11 42.2 0.0 0.00011 21.4 0.3 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 CCF52649.1 - 1.2e-06 27.7 0.2 0.042 12.7 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 CCF52649.1 - 4.4e-06 26.8 4.7 0.024 14.6 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCF52649.1 - 1.8e-05 24.8 0.9 0.021 14.8 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CCF52649.1 - 1.9e-05 24.1 1.7 0.49 9.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCF52649.1 - 2.4e-05 23.7 2.0 0.0042 16.5 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCF52649.1 - 0.00014 21.4 0.5 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 CCF52649.1 - 0.0002 21.4 1.0 1.3 9.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.12 CCF52649.1 - 0.00029 20.7 2.7 0.0091 15.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 CCF52649.1 - 0.00056 20.3 0.3 0.15 12.5 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CCF52649.1 - 0.00092 18.9 0.4 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 CCF52649.1 - 0.0011 18.8 0.7 0.16 11.8 0.2 3.1 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CCF52649.1 - 0.0011 19.3 2.2 0.8 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCF52649.1 - 0.0017 17.8 0.5 0.67 9.3 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 CCF52649.1 - 0.0037 18.0 0.1 0.059 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CCF52649.1 - 0.0053 15.4 0.3 0.41 9.2 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 CCF52649.1 - 0.013 14.7 0.9 1.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 CCF52649.1 - 0.014 14.8 1.2 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CCF52649.1 - 0.018 14.2 0.7 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ArgK PF03308.11 CCF52649.1 - 0.02 13.6 0.1 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 CCF52649.1 - 0.021 14.6 0.3 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCF52649.1 - 0.025 14.7 0.7 11 6.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CCF52649.1 - 0.028 14.3 1.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 CCF52649.1 - 0.048 13.3 0.9 8.4 6.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 CCF52649.1 - 0.056 12.3 0.1 0.33 9.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 CCF52649.1 - 0.082 12.4 0.4 0.51 9.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.24 CCF52649.1 - 0.088 12.3 0.1 6.6 6.1 0.0 2.7 3 0 0 3 3 2 0 DEAD/DEAH box helicase ResIII PF04851.10 CCF52649.1 - 0.091 12.5 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 CCF52649.1 - 0.1 11.6 0.2 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 CCF52649.1 - 0.11 12.8 1.5 1.8 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CCF52649.1 - 0.26 11.1 1.7 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family DUF2370 PF10176.4 CCF52650.1 - 3.4e-78 262.1 0.0 6.7e-78 261.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) RINT1_TIP1 PF04437.8 CCF52651.1 - 1.3e-63 215.2 0.0 1.2e-62 212.0 0.0 2.4 2 1 0 2 2 2 1 RINT-1 / TIP-1 family DUF4061 PF13270.1 CCF52651.1 - 0.058 13.4 1.3 0.6 10.2 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF4013 PF13197.1 CCF52652.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) WD40 PF00400.27 CCF52653.1 - 3.1e-09 36.3 5.9 0.42 10.5 0.0 6.0 5 2 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CCF52653.1 - 0.0012 19.0 0.4 2.2 8.6 0.0 3.9 3 0 0 3 3 3 1 PQQ-like domain Pox_Ag35 PF03286.9 CCF52653.1 - 0.0061 16.1 0.3 0.0061 16.1 0.2 2.4 2 0 0 2 2 2 1 Pox virus Ag35 surface protein FLO_LFY PF01698.11 CCF52653.1 - 1.9 7.2 8.2 6.1 5.5 3.9 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein SDA1 PF05285.7 CCF52653.1 - 7.9 5.6 20.5 2 7.6 7.0 2.2 2 0 0 2 2 2 0 SDA1 SH3_1 PF00018.23 CCF52654.1 - 3.3e-14 52.0 0.4 5.7e-14 51.2 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF52654.1 - 3.4e-14 52.1 0.1 6.2e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 CCF52654.1 - 2e-12 47.2 0.0 5.1e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 CCF52654.1 - 1.1e-09 37.5 0.1 2.3e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 CCF52654.1 - 1.9e-07 30.8 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCF52654.1 - 3.9e-05 23.7 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 CCF52654.1 - 0.0087 16.0 0.2 0.016 15.2 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 CCF52654.1 - 0.14 12.3 1.1 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain eIF3_subunit PF08597.5 CCF52654.1 - 0.19 11.2 6.1 0.38 10.2 4.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit tRNA_U5-meth_tr PF05958.6 CCF52656.1 - 1.7e-23 82.9 0.0 1.6e-21 76.3 0.0 3.0 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CCF52656.1 - 8.7e-11 41.6 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF52656.1 - 1.2e-06 29.0 0.0 3.6e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCF52656.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CCF52656.1 - 2.8e-05 23.5 0.0 5.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCF52656.1 - 3.4e-05 23.8 0.0 7.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCF52656.1 - 0.00017 20.9 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 CCF52656.1 - 0.0003 19.9 0.0 0.00061 18.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 CCF52656.1 - 0.00039 20.8 0.0 0.0011 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CCF52656.1 - 0.0013 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 CCF52656.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRAM PF01938.15 CCF52656.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 TRAM domain TPMT PF05724.6 CCF52656.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 CCF52656.1 - 0.16 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CENP-Q PF13094.1 CCF52657.1 - 0.042 13.8 5.5 0.066 13.2 3.8 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TPR_MLP1_2 PF07926.7 CCF52657.1 - 0.11 12.2 6.8 0.18 11.5 4.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein BTV_NS2 PF04514.7 CCF52657.1 - 3.1 6.5 5.4 4.1 6.1 3.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SKN1 PF03935.10 CCF52658.1 - 2e-180 600.2 1.5 2.6e-180 599.8 1.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Zn_clus PF00172.13 CCF52659.1 - 2.7e-08 33.5 11.7 5e-08 32.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Diphthamide_syn PF01866.12 CCF52660.1 - 4.5e-88 295.4 0.0 2.7e-31 108.9 0.0 4.1 2 1 1 4 4 4 4 Putative diphthamide synthesis protein IF4E PF01652.13 CCF52663.1 - 6.4e-50 168.9 0.0 9e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ADH_zinc_N PF00107.21 CCF52664.1 - 2.6e-26 91.7 0.1 6.6e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF52664.1 - 4.6e-14 53.3 0.1 3.3e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF52664.1 - 4.5e-11 42.4 0.1 1.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CPSase_L_chain PF00289.17 CCF52664.1 - 0.061 13.4 0.1 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AMP-binding PF00501.23 CCF52665.1 - 4.6e-94 315.1 0.1 5.7e-94 314.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF52665.1 - 2.4e-24 86.0 1.5 2.6e-22 79.5 0.1 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Clp1 PF06807.9 CCF52666.1 - 2.2e-24 86.3 0.0 4.4e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCF52666.1 - 0.0014 18.3 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CCF52666.1 - 0.0057 16.5 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 CCF52666.1 - 0.0067 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 CCF52666.1 - 0.0099 15.8 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NESP55 PF06390.7 CCF52666.1 - 0.01 15.2 1.5 0.017 14.5 1.0 1.2 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Dynamin_N PF00350.18 CCF52666.1 - 0.05 13.4 0.0 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 CCF52666.1 - 0.063 12.7 0.0 0.4 10.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CCF52666.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ECH PF00378.15 CCF52667.1 - 1e-22 80.4 0.1 4.2e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CCF52667.1 - 1.6e-15 57.2 0.0 5.5e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ATP-synt_B PF00430.13 CCF52667.1 - 3.1 7.6 7.4 0.2 11.4 1.3 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DMRL_synthase PF00885.14 CCF52668.1 - 1.6e-40 138.1 0.0 1.6e-22 79.7 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Frag1 PF10277.4 CCF52670.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family NAC PF01849.13 CCF52671.1 - 3.3e-20 71.3 0.0 5.5e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_E PF05680.7 CCF52672.1 - 1e-23 83.0 0.4 1e-23 83.0 0.3 1.1 1 0 0 1 1 1 1 ATP synthase E chain OmpH PF03938.9 CCF52672.1 - 0.07 13.0 2.5 0.082 12.8 1.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CBM_X2 PF03442.9 CCF52673.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain X2 WES_acyltransf PF03007.11 CCF52674.1 - 3.2e-17 62.9 0.0 5.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain WD40 PF00400.27 CCF52675.1 - 7.2e-48 158.8 27.0 1.8e-11 43.4 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCF52675.1 - 2.4e-28 98.9 0.0 5.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 CCF52675.1 - 0.11 12.1 0.0 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Metallophos PF00149.23 CCF52676.1 - 1.2e-43 148.9 0.1 1.5e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 CCF52677.1 - 1e-34 119.8 0.0 2.2e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52677.1 - 1.1e-22 80.4 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF52677.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.17 CCF52678.1 - 4e-58 192.9 0.1 2.1e-19 68.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52678.1 - 3.2e-43 145.5 0.0 3.5e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF52678.1 - 4.3e-24 84.1 0.0 6.7e-10 38.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF52678.1 - 2e-06 27.6 0.0 1.2 8.9 0.0 3.3 3 0 0 3 3 3 3 RNA binding motif Limkain-b1 PF11608.3 CCF52678.1 - 3.4e-05 23.4 0.0 0.3 10.8 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 SPOR PF05036.8 CCF52678.1 - 0.07 13.3 0.0 2.8 8.1 0.0 3.0 3 1 0 3 3 3 0 Sporulation related domain ATP-grasp_2 PF08442.5 CCF52678.1 - 0.078 12.3 0.0 26 4.0 0.0 3.1 3 0 0 3 3 3 0 ATP-grasp domain HAD PF12710.2 CCF52679.1 - 1.4e-14 54.7 0.0 1.8e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CCF52679.1 - 4.1e-09 36.1 0.0 7.8e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 CCF52679.1 - 0.00012 22.3 0.0 0.00052 20.2 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCF52679.1 - 0.00023 20.4 0.1 0.0013 17.9 0.0 1.9 2 0 0 2 2 2 1 Putative Phosphatase SpoU_sub_bind PF08032.7 CCF52679.1 - 0.099 12.8 0.0 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Hydrolase PF00702.21 CCF52679.1 - 0.12 12.7 1.0 0.93 9.8 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mem_trans PF03547.13 CCF52680.1 - 6e-36 123.5 5.6 1.2e-34 119.2 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein Sod_Fe_C PF02777.13 CCF52681.1 - 1.5e-34 118.0 0.6 2.5e-34 117.2 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCF52681.1 - 1.1e-32 112.0 4.4 1.1e-32 112.0 3.0 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 CCF52681.1 - 0.021 14.1 0.0 0.92 8.7 0.0 2.3 1 1 1 2 2 2 0 AsmA-like C-terminal region N2227 PF07942.7 CCF52682.1 - 2.7e-92 308.5 0.0 3.4e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein DUF747 PF05346.6 CCF52683.1 - 4.4e-124 413.8 3.6 5.6e-124 413.5 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TypeIII_RM_meth PF12564.3 CCF52683.1 - 0.026 14.4 1.2 0.1 12.5 0.8 2.1 1 1 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit G-patch_2 PF12656.2 CCF52685.1 - 5e-27 93.5 1.3 3.7e-26 90.7 0.3 2.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 CCF52685.1 - 6e-06 25.9 7.3 6e-06 25.9 5.0 2.2 2 0 0 2 2 2 1 G-patch domain AA_permease PF00324.16 CCF52686.1 - 2.1e-126 422.0 35.3 2.5e-126 421.8 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF52686.1 - 1.9e-37 128.8 38.3 2.4e-37 128.5 26.6 1.1 1 0 0 1 1 1 1 Amino acid permease Cupin_8 PF13621.1 CCF52687.1 - 6.8e-32 110.9 0.0 8.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CCF52687.1 - 4.8e-08 32.6 0.1 1.6e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 CCF52687.1 - 0.001 19.3 0.0 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 CCF52687.1 - 0.046 13.2 0.0 0.48 9.9 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Aldo_ket_red PF00248.16 CCF52692.1 - 6.2e-49 166.3 0.0 7.6e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_2 PF03727.11 CCF52693.1 - 1.6e-76 256.7 0.0 2.2e-76 256.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCF52693.1 - 4.7e-64 215.5 0.0 8.8e-64 214.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Amino_oxidase PF01593.19 CCF52694.1 - 8.3e-13 48.2 0.0 9.2e-12 44.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCF52694.1 - 7.8e-10 38.6 0.3 1.4e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCF52694.1 - 1.7e-05 24.9 0.1 9.9e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF52694.1 - 0.06 13.1 0.2 0.52 10.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCF52694.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rad51 PF08423.6 CCF52695.1 - 3.5e-10 39.2 0.1 2.9e-09 36.2 0.0 2.5 3 0 0 3 3 3 1 Rad51 AAA_25 PF13481.1 CCF52695.1 - 1.6e-05 24.3 0.3 0.0024 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 CCF52695.1 - 0.00013 21.1 0.1 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 CCF52695.1 - 0.055 12.5 2.8 0.23 10.4 0.1 2.7 3 0 0 3 3 3 0 recA bacterial DNA recombination protein AAA_18 PF13238.1 CCF52695.1 - 0.061 13.6 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCF52695.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cse1 PF08506.5 CCF52696.1 - 1.1e-129 432.2 0.1 5.9e-129 429.8 0.1 2.0 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 CCF52696.1 - 1.9e-112 375.7 0.1 1.1e-111 373.2 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CCF52696.1 - 3.4e-12 46.0 1.5 2.2e-11 43.4 1.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCF52696.1 - 0.00019 21.3 0.2 0.0045 16.9 0.0 3.6 3 0 0 3 3 3 1 Exportin 1-like protein rve PF00665.21 CCF52697.1 - 3e-06 27.3 0.1 4.4e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Integrase core domain NDUFA12 PF05071.11 CCF52698.1 - 4.1e-10 40.0 0.4 7.8e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 TPR_11 PF13414.1 CCF52699.1 - 3.2e-14 52.3 4.8 5e-11 42.0 0.6 2.4 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCF52699.1 - 4.6e-10 38.6 3.0 0.032 13.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF52699.1 - 2.3e-09 36.4 4.8 0.011 15.5 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF52699.1 - 5.2e-05 23.5 3.6 0.00068 19.9 0.4 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52699.1 - 0.00013 22.2 2.7 0.13 12.9 0.1 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCF52699.1 - 0.00015 21.7 3.4 0.00037 20.5 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCF52699.1 - 0.0015 18.4 5.1 0.031 14.1 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCF52699.1 - 0.0025 17.6 1.6 0.0074 16.1 0.3 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 CCF52699.1 - 0.0027 18.3 10.6 0.033 14.8 1.3 3.0 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF52699.1 - 0.026 14.3 1.6 3.4 7.6 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 CCF52699.1 - 0.54 10.5 9.6 0.04 14.2 1.6 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_17 PF13431.1 CCF52699.1 - 0.59 10.4 3.1 0.93 9.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt20 PF12090.3 CCF52700.1 - 0.01 15.2 0.6 0.023 14.0 0.4 1.6 1 0 0 1 1 1 0 Spt20 family GAGA_bind PF06217.7 CCF52700.1 - 0.095 12.6 9.4 0.5 10.2 2.5 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family DUF836 PF05768.9 CCF52701.1 - 8.9e-11 41.9 0.2 1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Robl_LC7 PF03259.12 CCF52702.1 - 3.5e-08 32.8 0.1 6e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain ubiquitin PF00240.18 CCF52703.1 - 1.6e-06 27.3 0.1 7.7e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCF52703.1 - 2.5e-05 24.4 0.0 0.0001 22.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CCF52703.1 - 0.021 14.4 0.0 0.081 12.6 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1657 PF07870.6 CCF52704.1 - 0.058 13.0 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Herpes_PAP PF03325.8 CCF52704.1 - 0.23 10.9 1.9 0.25 10.8 1.3 1.0 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein Arm PF00514.18 CCF52705.1 - 0.00012 21.7 0.2 0.0022 17.7 0.1 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat LacAB_rpiB PF02502.13 CCF52706.1 - 5.8e-43 145.8 1.0 6.7e-43 145.6 0.7 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF4514 PF14986.1 CCF52706.1 - 0.038 13.7 1.1 0.12 12.1 0.2 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4514) TIM PF00121.13 CCF52707.1 - 6.8e-57 192.3 0.0 8.2e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase TPR_16 PF13432.1 CCF52709.1 - 9.6e-09 35.6 9.6 6.2e-05 23.5 0.0 3.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52709.1 - 1.6e-07 31.3 11.3 0.21 12.3 1.0 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF52709.1 - 1.6e-07 30.6 4.2 0.67 10.0 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCF52709.1 - 6.4e-06 25.7 5.5 0.0017 17.9 2.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 CCF52709.1 - 6.8e-05 23.1 5.7 0.37 11.1 0.4 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCF52709.1 - 6.8e-05 22.3 0.7 2.2 8.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCF52709.1 - 0.0015 18.1 3.4 2.9 7.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCF52709.1 - 0.0053 16.8 0.3 5.3 7.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCF52709.1 - 0.006 15.6 2.4 0.006 15.6 1.7 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat GPI PF06560.6 CCF52709.1 - 0.08 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) HEAT_PBS PF03130.11 CCF52709.1 - 0.089 13.3 0.1 3.6 8.3 0.0 3.1 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat TPR_7 PF13176.1 CCF52709.1 - 0.17 11.7 2.3 46 4.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCF52709.1 - 0.54 10.1 5.1 3.8 7.4 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF52709.1 - 0.63 10.6 4.8 5 7.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52709.1 - 1.1 9.2 7.8 9.1 6.3 0.1 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 CCF52711.1 - 0.026 14.5 12.5 36 4.8 0.0 7.1 9 0 0 9 9 9 0 Leucine Rich repeat AMP-binding PF00501.23 CCF52712.1 - 6e-74 248.9 0.0 8.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCF52712.1 - 4.8e-63 212.3 0.5 5.4e-58 195.8 0.0 2.5 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.20 CCF52712.1 - 1.2e-37 129.3 3.3 6e-34 117.3 0.8 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCF52712.1 - 5e-23 81.6 2.9 7.9e-19 68.0 1.0 2.6 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 CCF52712.1 - 1.5e-21 76.9 0.2 5.2e-11 42.4 0.0 3.2 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCF52712.1 - 3.1e-20 72.9 0.0 3.4e-19 69.5 0.1 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 CCF52712.1 - 1.3e-12 47.0 1.6 2.9e-07 29.4 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCF52712.1 - 9.7e-09 35.4 1.4 0.00049 20.1 1.7 4.2 2 2 0 2 2 2 2 NADH(P)-binding RmlD_sub_bind PF04321.12 CCF52712.1 - 1.3e-08 34.1 0.1 1.6e-05 23.9 0.0 3.3 3 0 0 3 3 3 2 RmlD substrate binding domain PP-binding PF00550.20 CCF52712.1 - 1.3e-08 34.9 0.0 3.2e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CCF52712.1 - 3.4e-07 31.1 1.1 9.8e-07 29.6 0.1 2.5 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 CCF52712.1 - 3.6e-07 29.3 2.2 8.9e-05 21.5 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein DFP PF04127.10 CCF52712.1 - 0.034 13.7 1.7 0.19 11.2 1.2 2.1 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 CCF52712.1 - 0.077 12.8 1.0 0.23 11.2 0.7 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 CCF52712.1 - 0.29 10.3 1.7 4.3 6.5 0.7 2.7 3 0 0 3 3 3 0 NmrA-like family Peroxidase_2 PF01328.12 CCF52713.1 - 4.1e-18 65.1 0.0 6.3e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Transferase PF02458.10 CCF52714.1 - 3.7e-07 28.9 0.0 0.0052 15.2 0.0 2.1 2 0 0 2 2 2 2 Transferase family MFS_1 PF07690.11 CCF52715.1 - 8.5e-37 126.6 53.1 2.8e-36 124.9 35.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF52715.1 - 1.8e-14 53.1 7.7 1.8e-14 53.1 5.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CCF52715.1 - 6.7e-05 21.2 23.2 8.7e-05 20.9 16.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 CCF52715.1 - 1.8 6.5 3.5 9 4.2 1.3 2.1 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein AATase PF07247.7 CCF52716.1 - 0.07 11.6 0.0 0.13 10.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol acetyltransferase UDPGT PF00201.13 CCF52717.1 - 0.002 16.7 0.0 0.0069 14.9 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 CCF52717.1 - 0.027 14.2 0.1 0.13 12.0 0.0 2.3 2 1 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Glyco_transf_17 PF04724.8 CCF52719.1 - 6.4e-87 291.8 0.0 7.7e-87 291.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Aldedh PF00171.17 CCF52720.1 - 7.4e-182 604.8 0.2 8.3e-182 604.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF52720.1 - 2.5e-05 23.2 0.0 3.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) TRAM_LAG1_CLN8 PF03798.11 CCF52721.1 - 1e-08 34.9 13.3 1.5e-08 34.4 9.2 1.2 1 0 0 1 1 1 1 TLC domain Glyco_hydro_28 PF00295.12 CCF52722.1 - 4.8e-106 354.4 12.9 5.4e-106 354.2 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF221 PF02714.10 CCF52723.1 - 6.1e-98 327.6 8.3 6.1e-98 327.6 5.8 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCF52723.1 - 3.9e-38 130.4 5.0 3.9e-38 130.4 3.5 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCF52723.1 - 3.1e-20 72.4 1.7 5.3e-20 71.7 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 CCF52723.1 - 6.4e-13 48.4 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DUF2892 PF11127.3 CCF52723.1 - 0.073 12.9 0.3 0.073 12.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Cyclase PF04199.8 CCF52724.1 - 6.5e-12 45.4 1.8 1.4e-11 44.3 1.0 1.6 1 1 1 2 2 2 1 Putative cyclase PFK PF00365.15 CCF52725.1 - 3.7e-164 544.5 2.3 6.5e-96 320.6 0.8 3.3 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.1 CCF52725.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Pkinase PF00069.20 CCF52726.1 - 1.4e-56 191.5 0.0 4.7e-56 189.8 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52726.1 - 3.5e-24 85.2 0.0 8.5e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 CCF52726.1 - 1.9 6.6 6.5 2.9 6.0 4.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cut8_N PF14482.1 CCF52726.1 - 7.1 6.7 10.6 5.3 7.1 1.1 3.5 3 0 0 3 3 3 0 Cut8 proteasome-binding domain HVSL PF09749.4 CCF52727.1 - 6.6e-31 107.1 0.0 8.3e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Ribosomal_S24e PF01282.14 CCF52728.1 - 1.4e-32 111.2 0.0 1.4e-32 111.2 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S24e MRP-L47 PF06984.8 CCF52729.1 - 1.2e-15 57.1 1.3 2.5e-15 56.1 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 CCF52729.1 - 0.0019 17.8 0.2 0.065 12.9 0.0 2.4 2 0 0 2 2 2 1 Ribosomal L29 protein G-alpha PF00503.15 CCF52730.1 - 1.4e-112 376.2 0.5 1.7e-112 375.9 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCF52730.1 - 5e-13 48.6 0.1 3.6e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CCF52730.1 - 0.00029 21.3 0.0 1.2 9.7 0.0 2.5 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CCF52730.1 - 0.014 15.3 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CCF52730.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2985 PF11204.3 CCF52730.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Gtr1_RagA PF04670.7 CCF52730.1 - 0.061 12.4 0.4 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 CCF52730.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ribosomal_L37ae PF01780.14 CCF52731.1 - 3e-41 139.1 7.7 3.4e-41 139.0 5.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-BED PF02892.10 CCF52731.1 - 0.0032 17.1 2.6 0.48 10.2 1.8 2.3 1 1 0 1 1 1 1 BED zinc finger Zn_Tnp_IS1595 PF12760.2 CCF52731.1 - 0.0071 16.1 2.1 0.011 15.5 1.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCF52731.1 - 0.056 13.1 1.0 0.078 12.6 0.7 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 CCF52731.1 - 0.082 12.8 2.5 0.33 10.9 0.1 2.4 2 1 0 2 2 2 0 Zinc ribbon domain zf-FCS PF06467.9 CCF52731.1 - 0.11 12.1 2.0 0.14 11.8 0.2 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.5 CCF52731.1 - 0.11 11.9 2.5 0.23 10.9 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 CCF52731.1 - 0.22 11.2 2.6 0.32 10.7 1.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.8 CCF52731.1 - 0.24 11.1 3.2 0.37 10.5 2.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 CCF52731.1 - 2.4 8.6 6.5 1.7 9.1 1.0 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Ribosomal_L44 PF00935.14 CCF52731.1 - 3.4 7.7 7.6 4.7 7.2 1.9 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Alg6_Alg8 PF03155.10 CCF52732.1 - 1e-111 374.0 19.4 8.9e-53 179.7 0.1 3.1 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family Spc97_Spc98 PF04130.8 CCF52733.1 - 1.9e-96 323.5 0.0 2.3e-96 323.2 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Abhydrolase_3 PF07859.8 CCF52734.1 - 7.1e-35 120.5 0.0 1.2e-34 119.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CCF52734.1 - 7.9e-07 28.1 0.1 2.2e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 CCF52734.1 - 0.01 15.2 0.2 0.025 14.0 0.0 1.8 2 1 0 2 2 2 0 Putative esterase Abhydrolase_5 PF12695.2 CCF52734.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCF52734.1 - 0.09 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 CCF52734.1 - 0.11 11.2 0.2 0.65 8.7 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Chlorophyllase2 PF12740.2 CCF52734.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Topoisom_bac PF01131.15 CCF52735.1 - 0.09 11.5 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 DNA topoisomerase Glyco_hydro_45 PF02015.11 CCF52736.1 - 1.3e-53 182.0 15.4 1.6e-53 181.7 10.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF3414 PF11894.3 CCF52737.1 - 0 1445.4 0.0 0 1445.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) RNase_P_Rpp14 PF01900.14 CCF52738.1 - 6.3e-21 74.2 0.0 1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family IBR PF01485.16 CCF52739.1 - 1.5e-19 69.5 36.3 3e-11 43.0 2.0 4.3 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 CCF52739.1 - 5.3e-12 45.6 0.6 3.3e-11 43.0 0.4 2.2 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 CCF52739.1 - 2.7e-08 33.5 6.9 2.7e-08 33.5 4.8 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF52739.1 - 7e-07 29.1 7.3 7e-07 29.1 5.1 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF52739.1 - 2.1e-05 24.0 6.3 2.1e-05 24.0 4.4 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF52739.1 - 0.00046 19.8 2.0 0.00046 19.8 1.4 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 CCF52739.1 - 0.00055 19.6 7.6 0.00055 19.6 5.3 3.9 4 0 0 4 4 4 1 zinc-RING finger domain FYVE PF01363.16 CCF52739.1 - 1.7 8.6 28.2 0.49 10.3 1.4 3.6 3 1 0 3 3 3 0 FYVE zinc finger Baculo_RING PF05883.6 CCF52739.1 - 3.5 7.4 6.9 0.6 9.9 0.6 2.3 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain FYVE_2 PF02318.11 CCF52739.1 - 4.7 7.1 14.5 0.13 12.1 1.1 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger Glyco_transf_28 PF03033.15 CCF52740.1 - 1.2e-20 73.6 0.0 2.4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCF52740.1 - 1.7e-06 27.4 0.0 7.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 GRAM domain UDPGT PF00201.13 CCF52740.1 - 0.0013 17.4 0.1 0.003 16.1 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_BEACH PF14844.1 CCF52740.1 - 0.0043 16.8 0.0 4.2 7.2 0.0 3.0 2 0 0 2 2 2 2 PH domain associated with Beige/BEACH TPR_11 PF13414.1 CCF52741.1 - 1.5e-26 91.8 17.9 5.2e-13 48.4 0.1 3.6 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CCF52741.1 - 2.9e-23 80.4 1.9 1.2e-07 31.0 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF52741.1 - 7.8e-21 72.2 9.8 4.1e-06 26.2 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF52741.1 - 1.1e-12 46.7 0.1 0.017 14.8 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF52741.1 - 2.4e-12 46.0 4.9 0.00083 19.3 0.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCF52741.1 - 9.2e-12 44.5 11.0 0.0019 18.6 0.0 5.9 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF52741.1 - 1.5e-11 44.6 7.9 2.6e-07 31.1 0.1 5.7 5 2 2 7 7 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCF52741.1 - 1.7e-11 44.3 4.9 0.00083 19.6 0.6 4.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52741.1 - 2.9e-10 39.9 14.5 6e-06 26.1 0.0 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCF52741.1 - 2.3e-07 30.8 8.7 0.68 10.5 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF52741.1 - 7.6e-07 28.4 3.7 0.019 14.7 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCF52741.1 - 0.00014 21.9 4.6 0.0025 17.9 0.3 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CCF52741.1 - 0.00089 19.3 10.1 0.024 14.7 0.2 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat Sporozoite_P67 PF05642.6 CCF52741.1 - 0.016 13.0 4.6 0.024 12.5 3.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_9 PF13371.1 CCF52741.1 - 0.034 14.0 5.9 3.8 7.4 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat IncA PF04156.9 CCF52741.1 - 0.043 13.4 1.7 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 IncA protein Coatomer_E PF04733.9 CCF52741.1 - 0.11 11.6 1.7 1.9 7.5 0.0 2.7 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_10 PF13374.1 CCF52741.1 - 0.13 12.1 8.4 2 8.4 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat BTAD PF03704.12 CCF52741.1 - 0.72 10.1 16.7 0.26 11.5 1.8 4.3 4 1 1 5 5 4 0 Bacterial transcriptional activator domain TFIIA PF03153.8 CCF52741.1 - 7.8 6.2 14.2 15 5.3 9.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SHNi-TPR PF10516.4 CCF52743.1 - 4.6e-13 48.1 0.0 1.1e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 CCF52743.1 - 0.00031 20.3 1.6 0.051 13.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CCF52743.1 - 0.00051 19.9 4.5 0.014 15.2 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Phosphodiest PF01663.17 CCF52744.1 - 6e-63 213.3 0.0 7.3e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DLH PF01738.13 CCF52745.1 - 1.3e-23 83.4 0.2 3.3e-23 82.1 0.1 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCF52745.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PIN_4 PF13638.1 CCF52747.1 - 2.1e-22 79.6 0.1 4.8e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 PIN domain ORC2 PF04084.9 CCF52748.1 - 4.3e-82 275.5 0.0 5.4e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 VMA21 PF09446.5 CCF52749.1 - 8.7e-10 38.3 4.2 1.2e-09 37.8 2.9 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1229 PF06797.6 CCF52749.1 - 0.093 11.5 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) CwfJ_C_1 PF04677.10 CCF52750.1 - 1.6e-15 56.8 0.0 3.5e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.1 CCF52750.1 - 5.4e-06 25.7 0.4 1.4e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle CwfJ_C_2 PF04676.9 CCF52750.1 - 3.3e-05 24.2 0.0 8.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.18 CCF52750.1 - 0.0078 16.1 0.3 0.0078 16.1 0.2 2.1 2 0 0 2 2 2 1 Zinc knuckle RNA_pol_I_TF PF04090.7 CCF52751.1 - 0.03 13.5 0.1 0.11 11.7 0.0 1.8 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor Herpes_DNAp_acc PF04929.7 CCF52751.1 - 3.1 6.6 6.4 3.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Cnd1 PF12717.2 CCF52752.1 - 2.4e-64 216.4 5.7 5.4e-58 195.7 0.1 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCF52752.1 - 4e-55 186.0 0.6 1.7e-54 184.0 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CCF52752.1 - 2.1e-10 40.7 0.6 0.0012 19.0 0.0 6.1 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 CCF52752.1 - 2.6e-09 36.3 2.0 3.1 8.1 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.15 CCF52752.1 - 6.6e-07 28.0 1.1 0.00062 18.2 0.5 3.3 2 1 0 2 2 2 2 Adaptin N terminal region Cnd3 PF12719.2 CCF52752.1 - 1.2e-05 24.5 1.4 0.00011 21.3 0.2 2.5 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 CCF52752.1 - 0.0041 17.5 14.8 0.018 15.5 0.1 6.3 6 1 1 7 7 5 1 HEAT-like repeat DUF2435 PF10363.4 CCF52752.1 - 0.0069 16.2 0.1 9.8 6.1 0.0 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) SPX PF03105.14 CCF52752.1 - 0.0078 16.0 0.6 0.016 14.9 0.4 1.6 1 0 0 1 1 1 1 SPX domain FANCI_S2 PF14676.1 CCF52752.1 - 0.0087 15.9 1.3 0.35 10.7 0.0 3.7 4 0 0 4 4 4 1 FANCI solenoid 2 Cohesin_HEAT PF12765.2 CCF52752.1 - 0.013 15.4 0.6 0.59 10.1 0.0 4.0 3 1 1 4 4 4 0 HEAT repeat associated with sister chromatid cohesion PqqD PF05402.7 CCF52752.1 - 0.039 13.9 0.6 5.7 7.0 0.0 3.7 4 0 0 4 4 3 0 Coenzyme PQQ synthesis protein D (PqqD) CDC45 PF02724.9 CCF52752.1 - 0.3 9.0 7.4 0.51 8.3 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CCF52752.1 - 8.5 4.1 21.7 35 2.1 0.1 3.1 3 0 0 3 3 3 0 Nop14-like family Sec62 PF03839.11 CCF52753.1 - 4.5e-46 157.0 3.3 8.6e-46 156.1 2.3 1.5 1 1 0 1 1 1 1 Translocation protein Sec62 Glyco_hydro_43 PF04616.9 CCF52754.1 - 2.5e-06 26.8 0.6 3.8e-06 26.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PX PF00787.19 CCF52755.1 - 1.8e-17 63.1 0.2 5.7e-17 61.5 0.1 1.9 1 1 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 CCF52755.1 - 2.9e-11 43.0 0.1 6.4e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 CCF52755.1 - 0.0056 16.0 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain DUF1720 PF08226.6 CCF52755.1 - 0.0077 16.2 0.5 0.031 14.3 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1720) zf-C2H2 PF00096.21 CCF52756.1 - 2e-05 24.6 20.3 0.0016 18.6 5.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF52756.1 - 0.0023 18.1 14.7 0.05 13.9 1.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Complex1_LYR_1 PF13232.1 CCF52758.1 - 0.002 18.2 2.5 0.0024 18.0 0.3 2.2 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCF52758.1 - 0.0022 17.7 1.1 0.0063 16.2 0.8 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ORC6 PF05460.8 CCF52759.1 - 0.0034 16.5 2.6 0.0034 16.5 1.8 2.1 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) RRM_1 PF00076.17 CCF52760.1 - 2.5e-34 116.7 0.0 3.2e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52760.1 - 1.1e-26 92.5 0.0 2.8e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF52760.1 - 1.3e-08 34.5 0.0 0.00084 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF52760.1 - 0.43 10.4 1.0 4.5 7.1 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif Ribosomal_S5_C PF03719.10 CCF52761.1 - 1.3e-16 59.6 0.0 4.5e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CCF52761.1 - 1.6e-14 53.4 0.8 2.6e-14 52.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF793 PF05633.6 CCF52761.1 - 3.3 6.3 9.6 6.8 5.3 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Sec8_exocyst PF04048.9 CCF52762.1 - 3.4e-38 130.4 0.1 8.7e-38 129.1 0.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CCF52762.1 - 1.3e-05 24.3 0.2 2.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CCF52762.1 - 0.019 14.8 0.2 0.019 14.8 0.1 3.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Methyltransf_16 PF10294.4 CCF52763.1 - 1.3e-17 63.8 0.0 3.2e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase DUF1162 PF06650.7 CCF52764.1 - 5.4e-73 245.6 0.0 4.1e-69 232.8 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCF52764.1 - 2.1e-39 133.6 0.1 5.7e-39 132.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 CCF52764.1 - 1.2e-06 28.6 0.0 4.3e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain BTG PF07742.7 CCF52765.1 - 1.2e-24 86.0 0.0 3.1e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 BTG family zf-FPG_IleRS PF06827.9 CCF52765.1 - 0.019 14.5 0.9 0.039 13.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS PAT1 PF09770.4 CCF52765.1 - 1.9 6.6 17.7 3.3 5.8 12.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pol_alpha_B_N PF08418.5 CCF52766.1 - 1.4e-58 198.4 0.0 1.9e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CCF52766.1 - 3.2e-21 75.5 0.0 4.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Tau95 PF09734.4 CCF52767.1 - 7.2e-56 189.7 0.0 9.1e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit MukE PF04288.8 CCF52767.1 - 0.03 13.1 0.1 0.055 12.2 0.1 1.3 1 0 0 1 1 1 0 MukE-like family Ran_BP1 PF00638.13 CCF52768.1 - 4.6e-52 175.2 1.6 6.7e-52 174.6 1.1 1.2 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 CCF52768.1 - 1.2e-05 24.9 1.1 1.6e-05 24.5 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 CCF52768.1 - 7.1e-05 22.4 0.6 0.00037 20.2 0.4 1.9 1 1 0 1 1 1 1 WH1 domain EMP24_GP25L PF01105.19 CCF52769.1 - 1.4e-47 161.7 0.0 1.6e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Apocytochr_F_C PF01333.14 CCF52769.1 - 0.084 12.7 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Apocytochrome F, C-terminal Nop PF01798.13 CCF52770.1 - 5.7e-58 194.4 1.0 1.2e-57 193.4 0.7 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCF52770.1 - 3.8e-27 93.8 0.0 7.4e-27 92.9 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCF52770.1 - 1.8e-15 56.8 0.5 1.8e-15 56.8 0.3 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain AAA PF00004.24 CCF52771.1 - 2.7e-41 140.8 0.0 4.3e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF52771.1 - 4.7e-07 30.0 0.3 0.00011 22.3 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCF52771.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCF52771.1 - 4.7e-05 22.4 0.0 9.7e-05 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCF52771.1 - 0.00016 21.7 0.1 0.0015 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCF52771.1 - 0.00023 20.9 0.4 0.002 17.8 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCF52771.1 - 0.00087 18.4 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCF52771.1 - 0.0024 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCF52771.1 - 0.0042 16.5 0.6 0.71 9.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 CCF52771.1 - 0.0043 16.2 0.0 0.15 11.1 0.0 2.4 1 1 1 2 2 2 1 KaiC AAA_17 PF13207.1 CCF52771.1 - 0.0046 17.7 1.1 0.011 16.5 0.3 2.2 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCF52771.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCF52771.1 - 0.0055 16.3 0.1 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCF52771.1 - 0.0066 16.1 0.2 0.014 15.1 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCF52771.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CCF52771.1 - 0.0098 16.2 0.0 0.028 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CCF52771.1 - 0.023 13.5 0.0 0.061 12.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 CCF52771.1 - 0.024 14.6 0.5 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCF52771.1 - 0.047 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CCF52771.1 - 0.06 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCF52771.1 - 0.063 12.9 0.2 0.42 10.2 0.1 2.1 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.8 CCF52771.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 CCF52771.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Histone PF00125.19 CCF52771.1 - 0.08 13.0 0.2 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PhoH PF02562.11 CCF52771.1 - 0.12 11.6 0.2 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 CCF52771.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCF52771.1 - 0.16 11.4 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain Tim17 PF02466.14 CCF52772.1 - 1.1e-33 116.0 8.8 1.4e-33 115.6 6.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RRP7 PF12923.2 CCF52773.1 - 3.2e-34 117.7 4.3 1.5e-33 115.5 0.0 2.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 CCF52773.1 - 1.4e-06 27.7 0.0 5.8e-06 25.8 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52773.1 - 3.1e-05 23.8 0.1 8.3e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NTR2 PF15458.1 CCF52773.1 - 0.00019 20.7 3.2 0.00039 19.7 2.2 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Nop14 PF04147.7 CCF52773.1 - 0.0096 13.8 6.7 0.015 13.2 4.6 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CCF52773.1 - 0.022 13.2 4.4 0.028 12.9 3.1 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CCF52773.1 - 0.34 8.8 4.8 0.43 8.5 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4140 PF13600.1 CCF52773.1 - 2.2 8.7 9.0 0.8 10.1 2.3 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Paf1 PF03985.8 CCF52773.1 - 2.5 6.7 12.2 4.1 6.0 8.4 1.3 1 0 0 1 1 1 0 Paf1 Sporozoite_P67 PF05642.6 CCF52773.1 - 2.6 5.7 10.3 0.037 11.9 2.2 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen IMPDH PF00478.20 CCF52774.1 - 1e-136 455.5 0.1 4.9e-136 453.2 0.0 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCF52774.1 - 2.5e-19 68.7 0.0 1.2e-08 34.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CCF52774.1 - 2e-11 43.6 8.3 2e-08 33.7 5.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CCF52774.1 - 3.1e-08 32.8 4.7 5.1e-08 32.1 2.5 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCF52774.1 - 8.3e-08 31.7 2.8 3.6e-07 29.7 2.0 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CCF52774.1 - 0.00044 19.4 3.6 0.00059 18.9 1.6 1.9 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.7 CCF52774.1 - 0.01 14.8 0.8 0.11 11.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.12 CCF52774.1 - 0.028 13.2 1.2 0.3 9.8 0.0 2.3 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) QRPTase_C PF01729.14 CCF52774.1 - 0.083 12.4 0.8 0.9 9.0 0.1 2.6 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain DHO_dh PF01180.16 CCF52774.1 - 0.69 8.8 5.1 0.2 10.5 0.4 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase PcrB PF01884.12 CCF52774.1 - 0.75 8.9 3.5 9.5 5.3 0.1 3.3 3 1 0 3 3 3 0 PcrB family RVT_2 PF07727.9 CCF52775.1 - 5.5e-69 231.8 0.0 2.1e-67 226.6 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF52775.1 - 2.6e-07 30.7 0.1 1.2e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Hat1_N PF10394.4 CCF52777.1 - 6e-37 127.1 0.0 1.4e-36 125.9 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus MOZ_SAS PF01853.13 CCF52777.1 - 7.7e-05 22.0 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.1 CCF52777.1 - 0.00026 21.0 0.0 0.00097 19.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF52777.1 - 0.00032 20.6 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF52777.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 CCF52778.1 - 2.6e-73 246.7 24.2 8.4e-41 140.1 6.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCF52778.1 - 5.4e-51 172.4 0.1 8.3e-32 110.3 0.1 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCF52778.1 - 2.4e-05 23.6 0.0 0.3 10.2 0.2 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCF52778.1 - 9.8e-05 22.4 2.9 0.0086 16.0 0.3 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCF52778.1 - 0.00063 19.6 0.2 0.32 10.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCF52778.1 - 0.0027 17.1 0.9 2.6 7.6 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 CCF52778.1 - 0.0029 18.0 2.4 2.4 8.6 0.1 3.4 3 0 0 3 3 3 2 Miro-like protein DUF87 PF01935.12 CCF52778.1 - 0.0052 16.6 1.5 0.73 9.6 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 T2SE PF00437.15 CCF52778.1 - 0.0064 15.4 0.2 0.54 9.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 CCF52778.1 - 0.0065 15.6 0.4 3 6.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCF52778.1 - 0.0073 16.3 0.0 10 6.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCF52778.1 - 0.011 15.5 5.2 0.1 12.4 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AAA_25 PF13481.1 CCF52778.1 - 0.036 13.4 0.2 2.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCF52778.1 - 0.45 9.9 2.4 9.7 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Chitin_synth_2 PF03142.10 CCF52779.1 - 8.6e-291 964.9 0.0 1.1e-290 964.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCF52779.1 - 2.5e-17 63.2 1.1 6.6e-17 61.8 0.8 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF52779.1 - 1.5e-15 57.6 0.0 3.9e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CCF52779.1 - 3.7e-06 26.3 0.0 0.00062 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 CCF52779.1 - 1.3e-05 24.8 0.0 3.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCF52779.1 - 0.00085 19.0 0.0 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF2275 PF10039.4 CCF52779.1 - 0.23 11.3 0.0 0.46 10.3 0.0 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) 4HB_MCP_1 PF12729.2 CCF52779.1 - 4.8 6.5 3.5 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Cpn60_TCP1 PF00118.19 CCF52780.1 - 5.5e-141 470.5 10.3 7.4e-141 470.0 7.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UFD1 PF03152.9 CCF52781.1 - 9.1e-67 223.5 0.0 1.2e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-RING_5 PF14634.1 CCF52782.1 - 9.6e-08 31.6 1.6 2e-07 30.6 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Churchill PF06573.6 CCF52782.1 - 0.00015 21.7 0.2 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 Churchill protein KLRAQ PF10205.4 CCF52782.1 - 0.005 16.8 1.6 0.01 15.8 1.1 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein zf-RING_2 PF13639.1 CCF52782.1 - 0.12 12.2 2.0 0.6 9.9 1.3 2.2 1 1 0 1 1 1 0 Ring finger domain LMBR1 PF04791.11 CCF52782.1 - 0.21 10.1 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Viral_P18 PF04521.8 CCF52782.1 - 0.25 10.7 2.9 0.43 10.0 2.0 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein MTBP_C PF14920.1 CCF52782.1 - 0.95 8.9 8.1 0.046 13.1 1.5 1.7 2 0 0 2 2 2 0 MDM2-binding TerY-C PF15616.1 CCF52782.1 - 1.8 8.4 4.8 0.86 9.5 0.2 2.5 2 1 1 3 3 3 0 TerY-C metal binding domain zf-C3HC4 PF00097.20 CCF52782.1 - 8.5 6.1 8.6 96 2.7 4.3 2.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) JmjC PF02373.17 CCF52784.1 - 5.9e-08 32.9 0.0 1.7e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase ATP-synt_F6 PF05511.6 CCF52784.1 - 0.084 12.7 1.9 0.31 10.9 1.3 1.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Cupin_4 PF08007.7 CCF52784.1 - 0.29 10.3 5.8 2.2 7.4 2.0 2.7 3 0 0 3 3 3 0 Cupin superfamily protein ADH_zinc_N PF00107.21 CCF52785.1 - 2.4e-13 49.7 0.0 4.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF52785.1 - 2.1e-07 30.6 0.0 7e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sterol-sensing PF12349.3 CCF52786.1 - 1e-46 158.2 10.9 1.8e-46 157.3 7.5 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 CCF52786.1 - 8.7e-15 53.7 6.0 1.2e-14 53.2 4.2 1.1 1 0 0 1 1 1 1 Patched family Glyco_hydro_98M PF08306.6 CCF52786.1 - 0.26 9.9 0.0 0.42 9.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 6PGD PF00393.14 CCF52787.1 - 2.8e-134 446.8 0.0 3.4e-134 446.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCF52787.1 - 1.2e-53 181.3 0.0 1.7e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCF52787.1 - 0.028 14.8 0.1 0.053 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 CCF52787.1 - 0.036 14.1 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PA PF02225.17 CCF52787.1 - 0.059 13.0 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 PA domain Ub-Mut7C PF14451.1 CCF52787.1 - 0.16 11.5 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Mut7-C ubiquitin Het-C PF07217.6 CCF52788.1 - 7.5e-230 764.2 0.0 1.8e-229 762.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SSPI PF14098.1 CCF52788.1 - 0.032 14.1 0.2 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Small, acid-soluble spore protein I RPA_C PF08784.6 CCF52789.1 - 1.1e-16 61.0 0.5 1.1e-16 61.0 0.4 2.0 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CCF52789.1 - 7e-09 35.4 0.4 1.1e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Methyltransf_16 PF10294.4 CCF52790.1 - 4.5e-15 55.5 0.1 3.7e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCF52790.1 - 0.014 14.7 0.2 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain zf-MYND PF01753.13 CCF52791.1 - 2.2 8.2 8.4 15 5.5 0.0 3.2 3 0 0 3 3 3 0 MYND finger E1-E2_ATPase PF00122.15 CCF52792.1 - 5.6e-66 221.8 7.2 1.3e-65 220.6 0.5 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CCF52792.1 - 4.2e-24 86.1 0.7 1.1e-23 84.7 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF52792.1 - 5.7e-13 49.4 0.0 1.1e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF52792.1 - 5.1e-08 32.2 0.0 1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCF52792.1 - 0.0009 18.8 0.3 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YrvL PF14184.1 CCF52792.1 - 0.0014 18.4 4.5 0.0014 18.4 3.1 2.3 2 0 0 2 2 2 1 Regulatory protein YrvL Hydrolase_like2 PF13246.1 CCF52792.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit PLU-1 PF08429.6 CCF52793.1 - 1.5e-88 296.9 3.7 6.4e-87 291.5 1.8 2.7 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 CCF52793.1 - 1.7e-42 144.2 0.3 3.4e-42 143.2 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 CCF52793.1 - 6.1e-25 86.6 38.1 4.8e-12 45.3 2.5 4.4 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 CCF52793.1 - 3.5e-17 62.0 0.0 7.9e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 CCF52793.1 - 2.1e-16 59.1 1.0 4.8e-16 57.9 0.7 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 CCF52793.1 - 2.8e-12 46.5 0.3 2.1e-11 43.7 0.2 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.1 CCF52793.1 - 0.00053 19.2 22.2 0.036 13.3 2.5 3.8 3 0 0 3 3 3 3 PHD-finger TusA PF01206.12 CCF52793.1 - 0.022 14.3 0.3 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 Sulfurtransferase TusA zf-HC5HC2H PF13771.1 CCF52793.1 - 0.028 14.5 15.5 2.7 8.2 1.4 3.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain Thg1 PF04446.7 CCF52793.1 - 0.18 11.4 0.1 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 tRNAHis guanylyltransferase C1_1 PF00130.17 CCF52793.1 - 3.7 7.3 25.5 0.29 10.9 0.4 4.2 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AMP-binding PF00501.23 CCF52794.1 - 1.9e-73 247.2 0.0 2.3e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF52794.1 - 7.4e-08 33.2 0.1 2.8e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 CCF52796.1 - 2.9e-29 101.9 27.0 2.9e-29 101.9 18.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF52796.1 - 8.6e-11 41.0 8.2 8.6e-11 41.0 5.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter CLPTM1 PF05602.7 CCF52797.1 - 1e-114 383.6 0.0 3.3e-112 375.4 0.0 2.2 2 0 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CCF52797.1 - 9.9e-06 25.0 0.4 9.9e-06 25.0 0.3 2.3 3 0 0 3 3 3 1 PQ loop repeat DUF456 PF04306.8 CCF52797.1 - 0.1 12.6 3.3 3.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF456) zf-MYND PF01753.13 CCF52798.1 - 4.6e-06 26.4 16.0 4.6e-06 26.4 11.1 2.4 2 0 0 2 2 2 1 MYND finger Cyclin_N PF00134.18 CCF52799.1 - 1e-45 154.3 0.3 1.1e-42 144.6 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCF52799.1 - 4.2e-26 91.1 0.0 4.2e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Rad21_Rec8_N PF04825.8 CCF52801.1 - 2e-42 143.5 0.1 3.7e-42 142.7 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCF52801.1 - 2e-15 55.6 0.0 6.4e-15 54.0 0.0 1.9 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CCF52801.1 - 0.0031 17.1 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein NAD_binding_2 PF03446.10 CCF52802.1 - 9e-17 61.3 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCF52802.1 - 1.9e-10 40.8 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 CCF52802.1 - 1.4e-05 25.2 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCF52802.1 - 8.4e-05 22.9 0.0 0.00035 20.9 0.0 2.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent F-box-like PF12937.2 CCF52803.1 - 8.8e-13 47.7 1.5 8.8e-13 47.7 1.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCF52803.1 - 6.3e-08 32.0 0.3 6.3e-08 32.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain WD40 PF00400.27 CCF52803.1 - 0.0012 18.6 0.1 1.2 9.1 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ATP_synt_H PF05493.8 CCF52804.1 - 9.8e-21 73.5 3.6 1.1e-20 73.4 2.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 CCF52804.1 - 0.082 12.3 0.6 0.087 12.2 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3093 PF11292.3 CCF52804.1 - 0.22 11.3 2.4 0.24 11.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Syja_N PF02383.13 CCF52805.1 - 3.8e-83 278.8 0.0 5.4e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCF52805.1 - 3.1e-28 99.3 0.0 5.6e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asp PF00026.18 CCF52808.1 - 2.4e-62 210.9 0.1 3.7e-62 210.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCF52808.1 - 9.4e-06 25.6 0.1 2.9e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCF52808.1 - 2.8e-05 24.5 1.4 0.076 13.5 0.0 3.9 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 CCF52808.1 - 0.023 14.5 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1 PF07690.11 CCF52809.1 - 1.9e-35 122.2 51.1 1.5e-34 119.2 35.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF52809.1 - 8.5e-11 41.0 12.9 8.5e-11 41.0 8.9 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Abhydrolase_6 PF12697.2 CCF52810.1 - 4.2e-14 52.9 0.2 6.2e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF52810.1 - 3.3e-09 36.6 0.0 6e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CCF52810.1 - 0.022 14.0 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_M16_C PF05193.16 CCF52811.1 - 4.5e-45 153.5 0.0 7.4e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCF52811.1 - 7.9e-43 145.7 0.0 1.6e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Zn_clus PF00172.13 CCF52812.1 - 2.5e-08 33.6 7.7 4.1e-08 33.0 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF52812.1 - 1.9e-07 30.2 0.0 1.9e-06 26.9 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain PAT1 PF09770.4 CCF52812.1 - 6.3 4.9 37.1 10 4.1 25.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_13 PF13166.1 CCF52813.1 - 7.6e-05 21.3 112.7 0.0012 17.4 13.2 5.4 3 1 2 5 5 5 4 AAA domain Tropomyosin PF00261.15 CCF52813.1 - 0.00016 20.8 10.0 0.00016 20.8 6.9 9.3 3 3 3 7 7 7 1 Tropomyosin Tropomyosin_1 PF12718.2 CCF52813.1 - 0.00041 20.2 21.0 0.00041 20.2 14.6 10.9 4 3 6 10 10 10 2 Tropomyosin like Reo_sigmaC PF04582.7 CCF52813.1 - 0.00042 19.6 36.3 0.00045 19.5 1.3 6.0 3 1 3 6 6 6 3 Reovirus sigma C capsid protein Mto2_bdg PF12808.2 CCF52813.1 - 0.0037 17.3 11.5 0.0037 17.3 8.0 10.3 10 2 1 11 11 11 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Pox_A_type_inc PF04508.7 CCF52813.1 - 0.017 14.8 0.8 0.017 14.8 0.6 13.0 14 0 0 14 14 14 0 Viral A-type inclusion protein repeat CamS PF07537.6 CCF52814.1 - 0.12 11.3 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 CamS sex pheromone cAM373 precursor PHD PF00628.24 CCF52815.1 - 9e-08 31.6 10.6 1.5e-07 30.9 7.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCF52815.1 - 0.0023 17.1 7.0 0.0046 16.2 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 CCF52815.1 - 0.0024 17.5 5.3 0.0051 16.4 3.7 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger Telomere_reg-2 PF10193.4 CCF52816.1 - 2e-23 82.8 0.0 6.9e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein DUF605 PF04652.11 CCF52816.1 - 0.33 10.3 11.1 0.74 9.1 7.7 1.5 1 0 0 1 1 1 0 Vta1 like SNF2_N PF00176.18 CCF52817.1 - 3e-83 279.0 0.0 3e-83 279.0 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCF52817.1 - 4.8e-41 139.1 0.3 4.8e-41 139.1 0.2 2.5 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CCF52817.1 - 8.2e-33 113.1 2.7 8.2e-33 113.1 1.9 3.9 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 CCF52817.1 - 2.1e-14 53.1 0.0 8.1e-14 51.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF52817.1 - 4.2e-07 29.6 0.0 1.7e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCF52817.1 - 6.7e-07 29.3 3.8 9.6e-07 28.8 0.0 3.2 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 CCF52817.1 - 4.6e-05 23.3 0.0 0.0017 18.3 0.0 3.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1086 PF06461.6 CCF52817.1 - 0.0034 17.1 0.5 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.1 CCF52817.1 - 0.019 14.8 0.4 0.12 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain DEAD_2 PF06733.10 CCF52817.1 - 0.026 13.9 0.1 0.066 12.6 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 THF_DHG_CYH PF00763.18 CCF52818.1 - 1.1e-17 64.0 0.0 1.5e-15 57.2 0.0 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CCF52818.1 - 3e-15 55.6 0.1 2.7e-08 33.0 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 CCF52818.1 - 0.00028 21.0 0.1 0.17 11.9 0.0 2.3 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase SBP_bac_5 PF00496.17 CCF52818.1 - 0.043 12.6 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Hamartin PF04388.7 CCF52819.1 - 0.041 12.5 6.1 0.05 12.2 4.2 1.3 1 0 0 1 1 1 0 Hamartin protein DUF1777 PF08648.7 CCF52819.1 - 1.4 8.5 5.0 2.7 7.7 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Tet_JBP PF12851.2 CCF52820.1 - 7.6e-05 22.0 0.1 0.00018 20.8 0.1 1.6 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Neil1-DNA_bind PF09292.5 CCF52820.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind DUF2360 PF10152.4 CCF52820.1 - 0.038 14.2 0.2 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SMP PF04927.7 CCF52821.1 - 0.096 12.6 1.6 0.16 11.9 1.1 1.4 1 0 0 1 1 1 0 Seed maturation protein RRM_1 PF00076.17 CCF52823.1 - 3.7e-15 55.3 0.0 5.1e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF52823.1 - 1.2e-10 41.2 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF52823.1 - 6e-08 32.4 0.0 9.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCF52823.1 - 0.04 13.7 0.0 0.068 13.0 0.0 1.4 1 1 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 CCF52823.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GST_N_3 PF13417.1 CCF52824.1 - 3.9e-10 39.8 0.0 1.5e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF52824.1 - 5.4e-09 35.8 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF52824.1 - 1.4e-06 28.7 0.0 2.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF52824.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribonuclease_T2 PF00445.13 CCF52825.1 - 3.7e-39 134.3 1.9 5.4e-39 133.7 1.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Sec1 PF00995.18 CCF52826.1 - 2.1e-151 505.3 0.0 2.4e-151 505.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Birna_VP5 PF03042.9 CCF52826.1 - 0.17 11.4 0.4 0.33 10.4 0.3 1.4 1 0 0 1 1 1 0 Birnavirus VP5 protein tRNA-synt_1e PF01406.14 CCF52827.1 - 2.3e-121 404.6 0.0 3.4e-121 404.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCF52827.1 - 3.2e-09 35.9 0.2 9.8e-05 21.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCF52827.1 - 5.6e-05 21.3 0.7 0.018 13.0 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 CCF52827.1 - 0.0035 17.5 2.3 0.0052 17.0 0.0 2.4 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.13 CCF52827.1 - 0.04 12.5 0.0 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 CCF52827.1 - 0.042 12.5 1.5 0.065 11.8 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain HK PF02110.10 CCF52828.1 - 1.9e-63 213.9 1.3 7.9e-60 202.0 0.6 2.2 1 1 1 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCF52828.1 - 8.6e-45 152.0 0.0 1.6e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CCF52828.1 - 0.00012 21.4 0.1 0.00025 20.2 0.1 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MFS_1 PF07690.11 CCF52830.1 - 3.3e-46 157.6 42.0 4.9e-46 157.0 29.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2770 PF10968.3 CCF52830.1 - 0.59 9.8 6.1 1.5 8.5 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) DUF3402 PF11882.3 CCF52831.1 - 6e-157 522.9 0.0 5.6e-154 513.1 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 CCF52831.1 - 3e-38 131.3 0.0 4.7e-35 120.8 0.0 2.5 2 1 0 2 2 2 2 N1221-like protein NTF2 PF02136.15 CCF52832.1 - 1.1e-34 119.3 0.4 1.2e-34 119.1 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Calreticulin PF00262.13 CCF52833.1 - 6.7e-162 538.2 9.2 1e-161 537.6 6.4 1.3 1 0 0 1 1 1 1 Calreticulin family DUF883 PF05957.8 CCF52833.1 - 3.6 8.0 10.0 10 6.5 0.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Dynamin_M PF01031.15 CCF52834.1 - 3.4e-104 347.7 0.0 1.8e-103 345.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CCF52834.1 - 1.2e-54 184.6 0.0 2.2e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCF52834.1 - 8.1e-25 86.5 5.4 8.1e-25 86.5 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCF52834.1 - 0.0046 16.9 0.4 0.032 14.1 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dus PF01207.12 CCF52834.1 - 0.0088 14.9 0.0 0.017 13.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SKIP_SNW PF02731.10 CCF52835.1 - 4.3e-64 214.7 2.2 4.3e-64 214.7 1.5 2.0 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.7 CCF52835.1 - 0.0026 17.5 9.6 0.0061 16.3 6.7 1.6 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Bromodomain PF00439.20 CCF52836.1 - 9.9e-57 188.8 0.2 1.4e-20 72.9 0.1 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 CCF52836.1 - 6.3e-08 32.1 0.1 6.5e-05 22.1 0.0 2.8 1 1 1 3 3 3 2 Peptidase family M1 HEAT_2 PF13646.1 CCF52836.1 - 0.0075 16.5 6.1 0.37 11.0 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats RCC1 PF00415.13 CCF52838.1 - 2.4e-18 66.0 9.1 4.8e-05 23.4 0.1 6.2 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CCF52838.1 - 3.4e-16 59.2 0.0 3.1e-08 33.5 0.0 3.3 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.1 CCF52838.1 - 2.6e-07 30.0 13.8 0.019 14.5 0.0 5.7 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 CCF52838.1 - 2.8e-06 27.3 0.6 9.5e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCF52838.1 - 6e-06 26.6 0.2 1.7e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF52838.1 - 0.00016 21.5 0.4 1.1 9.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCF52838.1 - 0.0028 17.9 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) 6PF2K PF01591.13 CCF52839.1 - 1.1e-68 230.6 0.0 1.8e-68 229.9 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCF52839.1 - 1.5e-30 106.3 0.0 9e-30 103.8 0.0 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCF52839.1 - 3.7e-08 33.3 0.8 1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCF52839.1 - 0.012 16.3 0.3 0.048 14.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 CCF52839.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CS PF04969.11 CCF52840.1 - 3.6e-20 72.2 0.2 6.5e-20 71.4 0.1 1.4 1 0 0 1 1 1 1 CS domain RIB43A PF05914.7 CCF52840.1 - 0.016 13.8 0.4 0.016 13.8 0.3 1.9 2 0 0 2 2 2 0 RIB43A Metal_resist PF13801.1 CCF52840.1 - 0.021 14.8 2.5 2.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Ala_racemase_N PF01168.15 CCF52841.1 - 2.5e-32 112.2 0.6 2.9e-31 108.7 0.4 2.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain MCM_bind PF09739.4 CCF52841.1 - 4.2e-25 87.6 0.0 8.8e-25 86.6 0.0 1.5 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 CCF52841.1 - 2.1e-22 79.2 0.1 5e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Putative alanine racemase Ndr PF03096.9 CCF52841.1 - 0.028 12.9 0.0 0.049 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family NUDIX PF00293.23 CCF52842.1 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Cnd1 PF12717.2 CCF52842.1 - 0.03 14.1 0.0 30 4.4 0.0 3.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Bac_rhodopsin PF01036.13 CCF52843.1 - 7.2e-46 156.2 13.8 9.6e-46 155.8 9.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1810 PF08837.6 CCF52843.1 - 0.0083 15.7 0.1 0.74 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1810) DUF2754 PF10953.3 CCF52843.1 - 0.31 11.1 7.4 0.85 9.7 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Arteri_Gl PF00951.13 CCF52843.1 - 2.2 7.8 6.5 0.32 10.5 1.4 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein RNA_pol_Rpb1_5 PF04998.12 CCF52844.1 - 2.1e-88 296.1 0.1 4e-88 295.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCF52844.1 - 2.4e-59 199.9 0.0 6e-59 198.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCF52844.1 - 3e-37 127.8 0.0 6e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 CCF52844.1 - 3.8e-25 88.8 8.9 7.5e-22 78.0 0.0 4.7 5 1 0 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 CCF52844.1 - 5.3e-24 84.0 0.0 3e-23 81.6 0.0 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TGS PF02824.16 CCF52844.1 - 0.018 14.8 0.6 0.32 10.8 0.0 3.1 3 0 0 3 3 3 0 TGS domain K_oxygenase PF13434.1 CCF52846.1 - 1e-06 27.9 0.0 0.043 12.7 0.0 3.6 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CCF52846.1 - 6.8e-05 23.0 0.0 0.13 12.3 0.2 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF52846.1 - 0.00021 21.2 0.0 0.69 9.7 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF52846.1 - 0.0011 18.7 0.6 0.73 9.5 0.0 4.2 5 0 0 5 5 5 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CCF52846.1 - 0.026 14.6 0.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CCF52846.1 - 0.066 12.0 7.6 0.7 8.7 0.0 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase SSF PF00474.12 CCF52847.1 - 1.7e-18 66.4 20.0 2.4e-18 65.9 13.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family HAD_2 PF13419.1 CCF52848.1 - 3.4e-21 76.2 0.2 6.4e-21 75.3 0.1 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF52848.1 - 3.9e-07 29.7 0.0 9.1e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCF52848.1 - 0.00015 22.2 0.0 0.00021 21.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_2 PF13923.1 CCF52849.1 - 3.4e-09 36.5 8.3 6e-09 35.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF52849.1 - 1.2e-08 34.4 4.3 3.2e-08 33.0 3.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF52849.1 - 2.1e-07 30.6 8.4 3.3e-07 30.0 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCF52849.1 - 6.4e-06 25.7 3.9 1.1e-05 25.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52849.1 - 1.9e-05 24.2 5.6 3.6e-05 23.4 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCF52849.1 - 0.00013 21.7 4.7 0.00013 21.7 3.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCF52849.1 - 0.00076 19.1 2.8 0.00076 19.1 1.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FYVE PF01363.16 CCF52849.1 - 0.044 13.6 0.6 0.09 12.6 0.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 CCF52849.1 - 0.42 10.1 6.1 0.85 9.1 4.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Gly_transf_sug PF04488.10 CCF52850.1 - 6.2e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aminotran_5 PF00266.14 CCF52852.1 - 9.4e-30 103.5 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 CCF52852.1 - 0.023 14.5 0.1 0.076 12.8 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain UPF0180 PF03698.8 CCF52852.1 - 0.068 13.0 0.1 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) MitoNEET_N PF10660.4 CCF52853.1 - 0.52 10.2 3.0 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus NAD_binding_4 PF07993.7 CCF52854.1 - 1.1e-34 119.4 0.0 2.6e-34 118.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 CCF52854.1 - 7.5e-30 103.6 0.2 2e-28 98.9 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme PP-binding PF00550.20 CCF52854.1 - 9.5e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 CCF52854.1 - 9.5e-05 22.1 2.5 0.00045 19.9 1.8 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CCF52854.1 - 0.0018 17.7 0.0 0.01 15.3 0.0 2.3 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCF52854.1 - 0.025 14.5 3.6 0.32 10.9 1.4 3.2 2 1 0 2 2 2 0 short chain dehydrogenase LsmAD PF06741.8 CCF52855.1 - 2.9e-27 94.5 1.2 2.9e-27 94.5 0.8 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CCF52855.1 - 3.8e-16 58.7 0.0 8.1e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Miro PF08477.8 CCF52858.1 - 4.4e-39 133.6 0.0 8.9e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 CCF52858.1 - 1.9e-35 119.9 0.1 6.5e-35 118.2 0.0 1.9 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 CCF52858.1 - 8.2e-30 103.3 0.0 6.7e-19 67.8 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_2 PF08356.7 CCF52858.1 - 1e-27 95.6 0.0 5.3e-27 93.3 0.0 2.1 1 1 0 1 1 1 1 EF hand associated EF-hand_7 PF13499.1 CCF52858.1 - 5.9e-09 35.9 0.7 0.0038 17.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.18 CCF52858.1 - 6.5e-09 35.7 0.1 8.4e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_1 PF00036.27 CCF52858.1 - 4e-08 31.9 2.6 0.006 15.8 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CCF52858.1 - 9.7e-08 31.2 2.4 0.0058 16.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain Arf PF00025.16 CCF52858.1 - 1.2e-06 27.8 0.0 0.0048 16.1 0.0 3.3 3 0 0 3 3 3 1 ADP-ribosylation factor family EF-hand_5 PF13202.1 CCF52858.1 - 2.4e-05 23.4 5.7 0.041 13.2 0.4 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 CCF52858.1 - 0.00014 21.9 0.0 0.79 9.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain SRPRB PF09439.5 CCF52858.1 - 0.00015 21.0 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit EF-hand_8 PF13833.1 CCF52858.1 - 0.00055 19.5 2.5 0.073 12.6 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair AAA_18 PF13238.1 CCF52858.1 - 0.001 19.4 0.0 0.062 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CCF52858.1 - 0.0013 18.2 0.0 1.2 8.4 0.0 3.3 4 0 0 4 4 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CCF52858.1 - 0.002 17.8 0.3 0.25 11.0 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCF52858.1 - 0.0025 17.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCF52858.1 - 0.0049 16.3 0.0 0.15 11.5 0.0 2.6 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CCF52858.1 - 0.008 16.0 0.3 3.6 7.3 0.0 2.5 2 1 1 3 3 2 0 Dynamin family AAA_16 PF13191.1 CCF52858.1 - 0.009 16.0 0.2 3.1 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CCF52858.1 - 0.012 14.9 0.0 0.75 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCF52858.1 - 0.015 14.7 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 CCF52858.1 - 0.017 14.6 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 CCF52858.1 - 0.02 14.5 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NOG1 PF06858.9 CCF52858.1 - 0.026 14.4 0.1 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA PF00004.24 CCF52858.1 - 0.032 14.4 0.1 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CCF52858.1 - 0.033 13.7 0.2 3.3 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 CCF52858.1 - 0.034 13.6 0.3 15 5.0 0.0 3.6 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CCF52858.1 - 0.039 13.7 0.3 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 CCF52858.1 - 0.041 13.5 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 CCF52858.1 - 0.045 12.9 0.1 0.64 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Rnk_N PF14760.1 CCF52858.1 - 0.057 13.4 0.8 0.15 12.1 0.0 2.1 2 0 0 2 2 1 0 Rnk N-terminus FeoB_N PF02421.13 CCF52858.1 - 0.072 12.3 0.2 0.36 10.0 0.0 2.2 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 CCF52858.1 - 0.074 13.3 0.0 16 5.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 CCF52858.1 - 0.11 12.7 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CCF52858.1 - 0.12 12.2 0.1 15 5.4 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CCF52858.1 - 0.12 11.9 0.1 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 CCF52858.1 - 0.13 11.9 2.6 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 EF hand DUF2075 PF09848.4 CCF52858.1 - 0.15 10.9 0.2 0.57 9.1 0.1 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 CCF52858.1 - 0.17 11.3 1.4 3.8 6.9 0.1 3.0 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain VirE PF05272.6 CCF52858.1 - 0.18 11.2 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Virulence-associated protein E AAA_14 PF13173.1 CCF52858.1 - 0.19 11.6 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCF52858.1 - 0.21 10.6 0.1 13 4.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SPARC_Ca_bdg PF10591.4 CCF52858.1 - 0.22 11.5 0.6 11 6.1 0.0 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region NTPase_1 PF03266.10 CCF52858.1 - 0.26 11.0 0.4 1.2 8.8 0.0 2.2 2 1 1 3 3 2 0 NTPase G-alpha PF00503.15 CCF52858.1 - 0.28 9.8 0.0 4.2 5.9 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit USP7_ICP0_bdg PF12436.3 CCF52859.1 - 4.6e-85 284.8 2.7 5.2e-85 284.6 1.2 1.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CCF52859.1 - 4.4e-67 225.6 2.4 1.7e-65 220.4 0.5 2.6 2 1 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 CCF52859.1 - 2.1e-58 197.5 0.3 3.8e-58 196.7 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF52859.1 - 2.7e-31 109.0 0.0 4.3e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 CCF52859.1 - 6.8e-09 35.9 0.0 1e-07 32.2 0.0 3.0 2 1 0 2 2 2 1 MATH domain SDP_N PF12278.3 CCF52859.1 - 0.035 13.7 0.8 0.064 12.8 0.6 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal Rad60-SLD PF11976.3 CCF52859.1 - 0.089 12.4 0.3 2.2 8.0 0.0 3.1 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like SH3_9 PF14604.1 CCF52860.1 - 1.1e-10 40.9 0.0 1.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCF52860.1 - 1.7e-07 30.4 0.0 2.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCF52860.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3431 PF11913.3 CCF52860.1 - 0.013 14.9 1.3 0.022 14.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) DUF3377 PF11857.3 CCF52860.1 - 0.21 11.2 0.4 0.55 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Pex2_Pex12 PF04757.9 CCF52861.1 - 6.5e-40 136.9 0.9 9e-40 136.4 0.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CCF52861.1 - 6e-09 35.5 9.3 9.5e-09 34.9 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCF52861.1 - 2.7e-06 27.3 5.5 4.5e-06 26.6 3.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCF52861.1 - 1.6e-05 24.4 5.7 2.6e-05 23.7 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF52861.1 - 9.2e-05 22.3 8.7 0.00015 21.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF52861.1 - 0.0004 20.0 7.8 0.00064 19.4 5.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCF52861.1 - 0.00063 19.3 8.8 0.0011 18.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF52861.1 - 0.0012 18.6 4.4 0.0021 17.8 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CCF52861.1 - 0.015 14.9 1.3 0.015 14.9 0.9 2.0 2 1 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 CCF52861.1 - 0.061 12.8 2.8 0.11 12.0 1.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 CCF52861.1 - 0.53 9.4 5.7 0.2 10.8 0.8 2.2 1 1 1 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.1 CCF52861.1 - 1.4 8.8 7.4 0.55 10.1 2.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prp18 PF02840.10 CCF52862.1 - 9e-58 194.2 0.0 1.6e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 CCF52862.1 - 5.1e-12 44.8 5.5 1.4e-11 43.4 3.8 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF566 PF04484.7 CCF52862.1 - 0.36 10.2 17.6 0.2 11.1 10.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF566) TFIIF_alpha PF05793.7 CCF52862.1 - 2.8 6.2 9.9 5.7 5.1 6.9 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) COX6B PF02297.12 CCF52863.1 - 2.4e-20 72.3 8.8 3.1e-20 71.9 6.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CCF52863.1 - 0.015 15.2 0.3 0.015 15.2 0.2 2.0 2 0 0 2 2 2 0 CHCH domain UCR_hinge PF02320.11 CCF52863.1 - 0.054 13.4 0.4 0.085 12.8 0.2 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein mRNA_stabil PF13929.1 CCF52863.1 - 0.15 11.0 0.2 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 mRNA stabilisation APOBEC_C PF05240.9 CCF52863.1 - 0.58 9.6 2.9 0.74 9.2 1.5 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 CCF52863.1 - 1.2 8.9 5.9 4.6 7.1 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Nitroreductase PF00881.19 CCF52864.1 - 1.7e-11 44.2 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family CSTF_C PF14304.1 CCF52865.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal DUF2413 PF10310.4 CCF52865.1 - 1.2 7.8 6.9 0.5 9.1 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) Nop14 PF04147.7 CCF52865.1 - 7 4.4 5.8 9.4 4.0 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family DIM1 PF02966.11 CCF52866.1 - 4.6e-67 223.6 0.1 5.1e-67 223.4 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CCF52866.1 - 0.024 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DUF4318 PF14201.1 CCF52866.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) LUC7 PF03194.10 CCF52867.1 - 8.3e-73 245.0 0.3 8.3e-73 245.0 0.2 2.1 2 1 0 2 2 2 1 LUC7 N_terminus ChaC PF04752.7 CCF52868.1 - 3.6e-52 176.8 0.0 7.5e-52 175.8 0.0 1.5 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 CCF52868.1 - 1.6e-25 88.6 3.7 4.1e-25 87.2 2.5 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CCF52868.1 - 1.9e-10 40.5 4.0 2.1e-08 34.0 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF52868.1 - 3e-09 36.7 3.0 2.7e-06 27.3 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCF52868.1 - 4.6e-06 26.6 1.7 0.023 14.7 0.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Staphylokinase PF02821.11 CCF52868.1 - 0.0017 18.1 0.6 0.0042 16.8 0.4 1.6 1 0 0 1 1 1 1 Staphylokinase/Streptokinase family zf-C2H2 PF00096.21 CCF52868.1 - 0.013 15.7 3.3 0.73 10.2 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type ABM PF03992.11 CCF52868.1 - 0.041 13.9 0.2 0.51 10.4 0.1 2.7 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF3091 PF11291.3 CCF52868.1 - 0.066 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) zf-C2H2_4 PF13894.1 CCF52868.1 - 0.17 12.2 2.8 5.8 7.4 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2407_C PF13373.1 CCF52871.1 - 9.7e-17 61.2 0.2 1.2e-14 54.4 0.0 3.5 4 0 0 4 4 4 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCF52871.1 - 1.9e-12 47.1 3.9 6.5e-11 42.2 2.7 2.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 CCF52871.1 - 0.00074 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Raftlin PF15250.1 CCF52871.1 - 0.011 14.2 0.3 0.058 11.9 0.2 1.9 1 1 0 1 1 1 0 Raftlin Fungal_trans PF04082.13 CCF52872.1 - 3.2e-07 29.5 0.3 6.4e-07 28.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF52872.1 - 1.1e-05 25.2 10.5 2e-05 24.3 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CCF52873.1 - 3.9e-20 70.9 1.0 3.2e-05 23.6 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat FA_desaturase PF00487.19 CCF52874.1 - 6.6e-30 104.4 14.0 1e-29 103.7 9.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CCF52874.1 - 1.2e-19 69.2 0.8 2e-19 68.5 0.5 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Glycos_transf_1 PF00534.15 CCF52876.1 - 2.7e-28 98.5 0.0 8.4e-28 96.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCF52876.1 - 1.4e-08 34.6 0.0 0.0028 17.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCF52876.1 - 4.2e-06 26.9 0.2 5.3e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CCF52876.1 - 1.4e-05 25.2 0.0 8.2e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCF52876.1 - 0.0003 20.9 0.0 0.0008 19.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 ASL_C2 PF14698.1 CCF52877.1 - 0.0032 17.5 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SAM_2 PF07647.12 CCF52877.1 - 0.13 12.1 0.1 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF1180 PF06679.7 CCF52877.1 - 9.1 6.1 7.9 8.9 6.1 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) G-patch PF01585.18 CCF52878.1 - 7.3e-14 51.2 3.4 1.6e-13 50.2 2.4 1.6 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCF52878.1 - 7.9e-08 32.0 1.6 9e-08 31.8 0.1 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 CCF52878.1 - 0.025 14.6 1.1 0.045 13.8 0.8 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SOG2 PF10428.4 CCF52879.1 - 1.4e-126 422.8 2.9 1.4e-126 422.8 2.0 3.5 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 CCF52879.1 - 4.7e-17 61.1 5.4 1.2e-07 31.1 0.4 4.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF52879.1 - 2.3e-16 59.3 16.3 4.9e-09 35.8 0.5 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CCF52879.1 - 2.4e-09 35.9 4.7 0.3 11.2 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CCF52879.1 - 3.1e-05 23.4 8.5 2.2 8.8 0.1 6.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 CCF52879.1 - 0.058 13.4 5.8 1.2 9.4 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.1 CCF52879.1 - 0.1 12.1 1.7 1.1 8.7 0.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeat NMT PF01233.14 CCF52880.1 - 1.1e-77 259.2 0.0 1.7e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCF52880.1 - 3.5e-65 218.9 0.0 1.7e-63 213.4 0.0 2.4 2 1 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CCF52880.1 - 2.5e-05 24.1 0.0 7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF52880.1 - 0.045 13.7 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF52880.1 - 0.058 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RAB3GAP2_N PF14655.1 CCF52881.1 - 0.084 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_3 PF13570.1 CCF52881.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.3 5 0 0 5 5 5 0 PQQ-like domain Cwf_Cwc_15 PF04889.7 CCF52881.1 - 5.2 6.6 23.9 0.27 10.9 12.6 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cep57_MT_bd PF06657.8 CCF52882.1 - 1.8e-17 63.0 0.8 1.8e-17 63.0 0.6 3.2 3 1 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 CCD PF07860.6 CCF52882.1 - 0.055 12.9 0.0 0.19 11.1 0.0 2.0 1 0 0 1 1 1 0 WisP family C-Terminal Region RabGAP-TBC PF00566.13 CCF52883.1 - 4.9e-28 98.0 0.9 3.8e-27 95.1 0.1 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 CCF52883.1 - 1.7e-05 24.2 3.4 0.002 17.4 0.0 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF3548) YjeF_N PF03853.10 CCF52884.1 - 7e-34 116.8 0.0 9.4e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus GATA PF00320.22 CCF52886.1 - 1.4e-13 49.9 3.4 2.8e-13 48.9 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 CCF52886.1 - 1.3e-09 37.9 0.0 2.8e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CCF52886.1 - 1.5e-08 34.9 0.0 1.1e-07 32.1 0.0 2.3 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 CCF52886.1 - 2.3e-08 33.7 0.0 1.2e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 CCF52886.1 - 1.6e-06 28.1 0.0 5.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 CCF52886.1 - 0.018 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain TF_Zn_Ribbon PF08271.7 CCF52886.1 - 0.12 11.6 0.3 0.62 9.4 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding UBX PF00789.15 CCF52887.1 - 4.7e-13 49.0 0.0 9.2e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 CCF52887.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like ARGLU PF15346.1 CCF52887.1 - 0.43 10.3 23.9 0.9 9.2 16.5 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 WD40 PF00400.27 CCF52889.1 - 9.4e-42 139.4 19.5 1.9e-09 37.0 0.2 11.2 12 0 0 12 12 12 6 WD domain, G-beta repeat Utp12 PF04003.7 CCF52889.1 - 3.9e-16 58.9 0.0 6.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCF52889.1 - 0.00045 18.5 0.1 0.86 7.6 0.0 2.9 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCF52889.1 - 0.036 12.3 0.0 2.2 6.5 0.0 3.1 4 0 0 4 4 4 0 Cytochrome D1 heme domain DUF1513 PF07433.6 CCF52889.1 - 0.061 12.2 0.1 1.5 7.6 0.0 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) SUI1 PF01253.17 CCF52891.1 - 8.4e-31 105.6 2.7 1.1e-30 105.2 1.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Peptidase_S3 PF00944.14 CCF52891.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein DUF608 PF04685.8 CCF52891.1 - 0.14 10.8 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 CoA_trans PF01144.18 CCF52893.1 - 6e-105 349.2 0.7 4.7e-62 208.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DeoRC PF00455.17 CCF52893.1 - 0.0023 17.5 0.1 0.67 9.5 0.0 2.8 3 0 0 3 3 3 2 DeoR C terminal sensor domain AcetylCoA_hyd_C PF13336.1 CCF52893.1 - 0.0026 17.4 0.1 0.0055 16.3 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1_like PF12832.2 CCF52894.1 - 3.2e-20 71.7 0.1 3.2e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 MFS_1 like family DcpS_C PF11969.3 CCF52895.1 - 1.1e-13 51.4 3.3 1.4e-13 51.1 0.8 2.1 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCF52895.1 - 6.6e-11 42.6 6.9 0.0003 21.2 3.2 3.1 1 1 2 3 3 3 2 HIT domain DUF4463 PF14703.1 CCF52895.1 - 0.028 14.9 0.3 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Thioredoxin_8 PF13905.1 CCF52896.1 - 1.3e-09 38.0 0.0 7.9e-08 32.3 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like ArgJ PF01960.13 CCF52897.1 - 4.7e-131 436.7 0.0 5.9e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 ArgJ family DUF2611 PF11022.3 CCF52897.1 - 0.037 14.1 0.2 0.24 11.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) ATP-grasp PF02222.17 CCF52897.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain CENP-N PF05238.8 CCF52898.1 - 4.6e-77 259.7 0.0 6e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF1690 PF07956.6 CCF52899.1 - 4.1e-16 59.2 11.1 5.2e-16 58.8 7.7 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) STAT_int PF02865.12 CCF52899.1 - 0.0016 18.3 1.6 0.0079 16.1 0.5 2.0 1 1 1 2 2 2 1 STAT protein, protein interaction domain DUF4254 PF14063.1 CCF52899.1 - 0.055 13.0 4.9 0.11 12.0 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) Piwi PF02171.12 CCF52899.1 - 0.089 11.7 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Piwi domain Mnd1 PF03962.10 CCF52899.1 - 0.098 12.3 9.7 0.14 11.8 6.7 1.3 1 0 0 1 1 1 0 Mnd1 family HALZ PF02183.13 CCF52899.1 - 0.19 11.4 6.3 0.54 10.0 0.8 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 CCF52899.1 - 0.42 10.1 7.6 0.51 9.8 5.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 CCF52899.1 - 0.45 9.4 8.5 0.5 9.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4404 PF14357.1 CCF52899.1 - 0.54 10.7 7.0 14 6.2 2.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) FlaC_arch PF05377.6 CCF52899.1 - 1.2 9.0 6.0 1.7 8.5 0.9 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.14 CCF52899.1 - 2.5 5.8 5.4 2.9 5.6 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 CCF52899.1 - 2.6 7.6 7.0 6.1 6.4 1.7 2.4 2 0 0 2 2 2 0 Septum formation initiator TerB-C PF15615.1 CCF52899.1 - 3.1 8.0 9.0 4.3 7.5 4.3 2.0 1 1 1 2 2 2 0 TerB-C domain Seryl_tRNA_N PF02403.17 CCF52899.1 - 5.1 7.1 14.0 1.6 8.8 6.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phos_pyr_kin PF08543.7 CCF52900.1 - 6e-10 38.7 0.0 9.8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCF52900.1 - 1.1e-08 34.5 0.0 1.6e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase RED_N PF07808.8 CCF52901.1 - 2.6e-09 36.6 5.5 2.6e-09 36.6 3.8 2.0 1 1 0 1 1 1 1 RED-like protein N-terminal region Copper-fist PF00649.13 CCF52902.1 - 7.8e-14 50.5 1.7 7.8e-14 50.5 1.2 2.4 2 0 0 2 2 2 1 Copper fist DNA binding domain HAT PF02184.11 CCF52903.1 - 1.7e-23 81.9 51.7 8.5e-09 35.0 0.0 13.4 14 1 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 CCF52903.1 - 1.1e-17 62.9 29.1 0.00092 19.6 0.0 12.0 6 2 7 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCF52903.1 - 5.2e-14 50.9 6.4 0.01 15.7 0.1 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCF52903.1 - 7e-11 41.6 4.5 0.0055 16.3 0.0 6.7 5 2 3 8 8 8 4 TPR repeat TPR_19 PF14559.1 CCF52903.1 - 2.1e-10 40.7 11.4 0.0087 16.3 0.0 7.8 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF52903.1 - 3e-09 37.2 23.2 0.00052 20.6 0.0 7.5 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCF52903.1 - 1.6e-08 33.8 0.1 0.43 10.2 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCF52903.1 - 1.6e-08 33.7 0.0 0.0061 16.2 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCF52903.1 - 3.4e-07 29.9 0.4 0.00059 19.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCF52903.1 - 2.3e-06 27.4 18.6 0.12 12.3 0.2 7.9 7 2 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCF52903.1 - 2.6e-05 23.6 24.2 0.87 9.5 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCF52903.1 - 0.0004 20.1 3.6 0.23 11.3 0.0 4.5 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Mad3_BUB1_I PF08311.7 CCF52903.1 - 0.027 14.2 19.6 0.033 13.9 1.6 5.7 5 2 1 6 6 6 0 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.6 CCF52903.1 - 0.03 14.0 0.1 0.03 14.0 0.1 6.2 6 3 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 CCF52903.1 - 9.7 6.9 21.9 85 3.9 0.1 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat SET PF00856.23 CCF52904.1 - 2e-26 93.2 0.1 2e-26 93.2 0.1 3.9 4 1 0 4 4 4 1 SET domain N-SET PF11764.3 CCF52904.1 - 3.8e-21 75.7 0.0 3.8e-21 75.7 0.0 4.9 4 2 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 CCF52904.1 - 0.00011 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Metallophos_2 PF12850.2 CCF52905.1 - 1.7e-19 70.2 0.0 2.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CCF52905.1 - 7.8e-05 22.1 2.2 0.059 12.7 1.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Borrelia_P83 PF05262.6 CCF52905.1 - 0.012 13.9 12.7 0.019 13.2 8.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CENP-B_dimeris PF09026.5 CCF52905.1 - 0.069 13.3 0.5 0.069 13.3 0.3 1.8 1 1 1 2 2 2 0 Centromere protein B dimerisation domain FAM60A PF15396.1 CCF52905.1 - 0.17 11.6 3.0 0.23 11.1 2.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Spore_coat_CotO PF14153.1 CCF52905.1 - 1.1 8.7 9.1 1.4 8.3 6.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.3 CCF52905.1 - 1.1 7.7 6.7 1.7 7.1 4.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 CCF52905.1 - 1.2 9.0 8.2 1.5 8.6 5.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CCF52905.1 - 1.3 6.9 6.2 1.6 6.6 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CCF52905.1 - 1.6 6.3 3.8 1.8 6.1 2.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CCF52905.1 - 2 6.9 6.4 2.5 6.6 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.5 CCF52905.1 - 2.4 8.1 17.5 3.6 7.5 12.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 CCF52905.1 - 3.2 7.0 21.4 4.8 6.4 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CCF52905.1 - 5.1 6.7 8.9 0.17 11.5 0.4 2.0 1 1 1 2 2 2 0 FAM176 family Ycf1 PF05758.7 CCF52905.1 - 9.7 3.7 7.1 12 3.4 4.9 1.0 1 0 0 1 1 1 0 Ycf1 Pentapeptide_2 PF01469.13 CCF52908.1 - 3e-07 29.9 9.1 0.00011 21.7 1.3 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 CCF52908.1 - 0.0012 18.5 5.9 0.0025 17.5 4.1 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) LSM PF01423.17 CCF52909.1 - 7e-17 60.7 0.1 8.7e-17 60.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Toxin_60 PF15607.1 CCF52909.1 - 0.08 12.9 0.0 0.083 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 60 Arf PF00025.16 CCF52910.1 - 5.6e-75 250.3 0.1 6.3e-75 250.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCF52910.1 - 1.8e-13 50.1 0.0 2.1e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCF52910.1 - 5.2e-12 45.1 0.5 2.2e-07 29.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CCF52910.1 - 5.4e-11 42.0 0.0 6.6e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCF52910.1 - 6.5e-11 41.8 0.0 7.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF52910.1 - 8.9e-08 32.6 0.0 1.2e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCF52910.1 - 3.7e-05 23.6 0.0 7.7e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF52910.1 - 0.01 15.2 0.0 0.073 12.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCF52910.1 - 0.059 12.6 0.2 0.29 10.4 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF21 PF01595.15 CCF52912.1 - 1.1e-33 116.0 0.3 1.8e-33 115.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCF52912.1 - 3.4e-05 23.5 0.5 1.5 8.6 0.0 3.7 3 0 0 3 3 3 3 CBS domain Aldo_ket_red PF00248.16 CCF52913.1 - 2.7e-32 111.7 0.0 8.8e-32 110.0 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family PCI PF01399.22 CCF52914.1 - 1.5e-18 67.0 1.4 2.6e-18 66.2 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 CCF52914.1 - 0.00096 19.7 11.6 0.28 11.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Vps39_1 PF10366.4 CCF52914.1 - 0.036 14.0 2.1 0.092 12.7 0.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 Apc3 PF12895.2 CCF52914.1 - 0.075 13.1 2.0 0.54 10.4 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCF52914.1 - 3 7.8 9.2 33 4.5 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 CCF52915.1 - 3.2e-31 108.5 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF52915.1 - 0.045 12.8 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_tran PF00005.22 CCF52916.1 - 2.2e-34 118.6 0.0 5.7e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCF52916.1 - 8.3e-25 87.7 13.5 1.3e-24 87.0 9.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CCF52916.1 - 5.1e-06 26.6 0.0 0.0049 16.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 CCF52916.1 - 8.9e-06 25.0 0.2 0.00048 19.4 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCF52916.1 - 0.00013 22.0 0.5 0.00013 22.0 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CCF52916.1 - 0.0014 17.8 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCF52916.1 - 0.0015 18.6 0.1 0.0072 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCF52916.1 - 0.0057 15.7 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 CCF52916.1 - 0.0064 15.9 0.1 0.024 14.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 CCF52916.1 - 0.022 14.9 0.0 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCF52916.1 - 0.045 13.1 0.1 0.67 9.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 CCF52916.1 - 0.081 12.6 0.0 4.9 6.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2408 PF10303.4 CCF52917.1 - 4.2e-55 185.5 0.7 2.2e-38 131.4 0.0 4.5 3 1 1 4 4 4 4 Protein of unknown function (DUF2408) DUF972 PF06156.8 CCF52917.1 - 0.0016 18.7 0.1 0.13 12.6 0.0 3.3 4 1 0 4 4 4 1 Protein of unknown function (DUF972) NP1-WLL PF11733.3 CCF52917.1 - 0.037 14.2 1.0 0.15 12.3 0.7 2.0 1 0 0 1 1 1 0 Non-capsid protein NP1 PilJ PF13675.1 CCF52917.1 - 0.1 12.9 5.0 0.31 11.3 0.4 3.0 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF724 PF05266.9 CCF52917.1 - 0.17 11.5 1.8 0.28 10.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fib_alpha PF08702.5 CCF52917.1 - 0.96 9.5 4.6 0.96 9.5 0.0 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.1 CCF52917.1 - 1.3 8.8 3.5 0.7 9.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) CDC45 PF02724.9 CCF52917.1 - 7.9 4.3 9.1 2.5 6.0 2.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Ran_BP1 PF00638.13 CCF52918.1 - 3.5e-14 52.9 0.4 6.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF948 PF06103.6 CCF52918.1 - 0.21 11.4 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Gti1_Pac2 PF09729.4 CCF52919.1 - 7e-45 152.9 0.1 2.5e-35 121.8 0.0 2.6 1 1 1 2 2 2 2 Gti1/Pac2 family RVP PF00077.15 CCF52922.1 - 0.0046 16.8 0.7 0.0073 16.2 0.2 1.6 1 1 1 2 2 2 1 Retroviral aspartyl protease DGC PF08859.6 CCF52922.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 DGC domain RVT_2 PF07727.9 CCF52923.1 - 3.1e-36 124.6 0.1 3.4e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zds_C PF08632.5 CCF52924.1 - 6.2e-22 76.7 0.9 1.2e-21 75.8 0.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Polysacc_deac_1 PF01522.16 CCF52926.1 - 2.4e-28 98.2 0.0 4.5e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1180 PF06679.7 CCF52926.1 - 1 9.2 3.2 2.3 8.1 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SAP PF02037.22 CCF52927.1 - 0.12 11.9 0.1 0.31 10.5 0.1 1.8 1 0 0 1 1 1 0 SAP domain RdRP PF05183.7 CCF52928.1 - 6.4e-109 365.2 0.0 8.9e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Aconitase PF00330.15 CCF52929.1 - 5.8e-156 519.6 0.0 1.5e-155 518.2 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCF52929.1 - 3.8e-33 114.3 0.0 7.1e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 CCF52929.1 - 2e-07 30.9 1.2 1e-06 28.6 0.6 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 CwfJ_C_1 PF04677.10 CCF52930.1 - 1.3e-20 73.2 0.0 1.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCF52930.1 - 2.3e-09 37.5 3.9 2.5e-09 37.4 0.0 2.9 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Macoilin PF09726.4 CCF52930.1 - 1.1 7.4 17.8 1.7 6.7 12.4 1.4 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M13_N PF05649.8 CCF52931.1 - 4.8e-101 338.6 0.0 6.1e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CCF52931.1 - 1.2e-57 194.4 0.0 1.8e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 IMD PF08397.6 CCF52931.1 - 0.73 9.1 5.7 1.3 8.3 3.9 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF2040 PF09745.4 CCF52932.1 - 4e-37 126.8 25.7 4e-37 126.8 17.8 2.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Vps55 PF04133.9 CCF52933.1 - 2e-46 156.6 4.5 2.2e-46 156.4 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Herpes_LMP1 PF05297.6 CCF52933.1 - 0.36 9.6 2.1 0.46 9.3 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-RING_4 PF14570.1 CCF52934.1 - 3.7e-21 74.4 11.5 6e-21 73.7 8.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCF52934.1 - 7.2e-06 25.5 8.2 1.2e-05 24.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 CCF52934.1 - 0.0015 18.3 1.0 0.0039 16.9 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF52934.1 - 0.0024 17.4 0.1 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CCF52934.1 - 0.01 15.8 12.1 0.017 15.0 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CCF52934.1 - 0.018 14.7 3.6 0.041 13.6 2.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 CCF52934.1 - 0.65 9.7 11.5 1.2 8.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CCF52934.1 - 1.5 8.5 9.8 0.49 10.1 4.4 1.8 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) SRP54 PF00448.17 CCF52935.1 - 1.4e-75 253.0 0.1 1.4e-75 253.0 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CCF52935.1 - 2.5e-21 75.8 0.1 2.5e-21 75.8 0.1 4.8 4 1 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 CCF52935.1 - 3.7e-12 46.1 0.1 8.3e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CCF52935.1 - 2.8e-06 27.2 0.5 7.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCF52935.1 - 9.3e-06 25.1 0.3 2.8e-05 23.6 0.1 1.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCF52935.1 - 0.00041 20.0 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 CCF52935.1 - 0.0014 18.5 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF52935.1 - 0.003 17.5 0.1 0.051 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCF52935.1 - 0.0041 17.2 0.1 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 CCF52935.1 - 0.0067 15.8 0.2 0.03 13.7 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CCF52935.1 - 0.0092 16.7 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCF52935.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 CCF52935.1 - 0.056 13.7 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CCF52935.1 - 0.07 12.6 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CCF52935.1 - 0.093 12.1 0.1 0.3 10.5 0.1 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CCF52935.1 - 0.094 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TrwB_AAD_bind PF10412.4 CCF52935.1 - 0.14 10.7 1.1 1.4 7.4 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Arm PF00514.18 CCF52936.1 - 0.03 14.1 0.9 2.7 7.9 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat KAP PF05804.7 CCF52936.1 - 0.2 9.5 0.1 0.56 8.0 0.0 1.7 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) Rot1 PF10681.4 CCF52937.1 - 1.3e-54 184.7 3.1 1.6e-54 184.4 2.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VanZ PF04892.7 CCF52938.1 - 1.8e-08 34.4 2.4 3.4e-08 33.5 1.7 1.5 1 1 0 1 1 1 1 VanZ like family Cytochrom_B_C PF00032.12 CCF52938.1 - 0.29 11.3 2.6 0.21 11.8 0.3 1.7 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DctQ PF04290.7 CCF52938.1 - 0.87 9.3 5.0 7.1 6.4 0.0 2.8 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component RseC_MucC PF04246.7 CCF52938.1 - 1 8.9 5.8 0.85 9.1 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TauE PF01925.14 CCF52938.1 - 2.5 7.4 13.0 0.18 11.2 3.2 2.1 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE FBPase PF00316.15 CCF52940.1 - 6.4e-128 426.1 0.0 7.6e-128 425.8 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CCF52940.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family IncFII_repA PF02387.10 CCF52940.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family WD40 PF00400.27 CCF52941.1 - 0.00051 19.8 2.5 10 6.1 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat DNA_ligase_A_C PF04679.10 CCF52941.1 - 0.067 13.6 0.2 10 6.6 0.1 2.7 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region Cyclin_N PF00134.18 CCF52942.1 - 5.6e-13 48.5 0.1 1.6e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCF52942.1 - 1.2e-11 45.2 0.4 3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Cyclin CDC45 PF02724.9 CCF52942.1 - 0.00027 19.1 6.7 0.00036 18.7 4.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Ndc1_Nup PF09531.5 CCF52942.1 - 6.8 4.9 8.9 12 4.2 6.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 CCF52943.1 - 2.5e-08 33.0 39.0 2.5e-07 29.7 19.6 4.1 3 1 0 4 4 4 2 Major Facilitator Superfamily PAH PF02671.16 CCF52944.1 - 3.2e-45 151.5 2.6 7.5e-18 63.8 0.8 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCF52944.1 - 1.4e-39 133.8 0.4 3.9e-39 132.4 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Ribosomal_S21e PF01249.13 CCF52945.1 - 3.4e-35 119.8 0.0 3.8e-35 119.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 CCF52945.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) MFS_1 PF07690.11 CCF52946.1 - 8.5e-32 110.2 32.2 8.5e-32 110.2 22.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 CCF52946.1 - 0.34 11.0 0.1 0.34 11.0 0.1 3.3 2 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding Cytochrom_C PF00034.16 CCF52947.1 - 6.5e-09 36.5 0.1 1.2e-08 35.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCF52947.1 - 9.2e-09 35.3 1.5 1.3e-07 31.6 1.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCF52947.1 - 0.00021 20.7 1.3 0.0014 18.1 0.9 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain MARVEL PF01284.18 CCF52948.1 - 3e-06 27.1 19.6 2.3e-05 24.2 13.6 2.2 1 1 1 2 2 2 2 Membrane-associating domain DUF3753 PF12575.3 CCF52948.1 - 0.43 10.3 2.6 12 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) SUR7 PF06687.7 CCF52948.1 - 1.2 8.7 12.9 0.45 10.0 3.7 2.1 2 0 0 2 2 2 0 SUR7/PalI family ABC2_membrane_4 PF12730.2 CCF52948.1 - 1.3 8.0 23.0 10 5.1 15.9 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4064 PF13273.1 CCF52948.1 - 2 8.5 12.9 3.5 7.7 4.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) OppC_N PF12911.2 CCF52948.1 - 6.3 6.2 12.0 0.91 8.9 0.3 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ribosomal_S4e PF00900.15 CCF52950.1 - 3.9e-31 106.5 1.2 5.6e-31 106.0 0.3 1.7 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCF52950.1 - 2.1e-07 30.6 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 CCF52950.1 - 6.3e-05 22.5 2.1 0.00029 20.4 1.4 2.2 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 CCF52950.1 - 0.00027 20.3 0.0 0.0006 19.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain HMG_box PF00505.14 CCF52951.1 - 2.6e-13 50.0 3.4 6e-13 48.8 2.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF52951.1 - 5.2e-06 26.7 0.8 1.5e-05 25.2 0.6 1.9 1 0 0 1 1 1 1 HMG-box domain Cyclin PF08613.6 CCF52952.1 - 1.1e-32 113.4 0.0 1e-21 77.9 0.0 3.5 5 0 0 5 5 5 2 Cyclin Preseq_ALAS PF09029.5 CCF52952.1 - 0.057 13.4 0.3 0.21 11.5 0.2 2.0 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Reprolysin_5 PF13688.1 CCF52953.1 - 1.3e-42 145.9 7.9 1.3e-42 145.9 5.5 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 CCF52953.1 - 4.1e-37 127.9 5.1 1.2e-36 126.3 3.6 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CCF52953.1 - 1.5e-36 125.8 1.2 2.9e-36 124.9 0.8 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 CCF52953.1 - 2.1e-19 70.2 0.1 2.1e-19 70.2 0.1 2.4 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 CCF52953.1 - 1.2e-14 54.3 26.3 1.2e-14 54.3 18.2 4.2 2 1 2 4 4 4 1 Disintegrin Reprolysin PF01421.14 CCF52953.1 - 7e-10 38.8 9.0 5e-07 29.4 6.3 3.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 CCF52953.1 - 1.9e-07 30.9 0.1 3.6e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.8 CCF52953.1 - 0.019 14.5 0.4 0.019 14.5 0.3 2.2 2 1 1 3 3 3 0 Pregnancy-associated plasma protein-A Histone PF00125.19 CCF52954.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCF52954.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CCF52954.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CCF52954.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CCF52954.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 CCF52955.1 - 6.5e-30 103.0 0.8 9.9e-30 102.4 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCF52955.1 - 2e-05 24.6 0.0 3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCF52955.1 - 0.0008 19.4 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCF52955.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Thiolase_N PF00108.18 CCF52956.1 - 2.2e-81 272.7 2.4 2.9e-81 272.3 1.7 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF52956.1 - 3.3e-42 142.7 0.6 3.3e-42 142.7 0.4 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 CCF52956.1 - 0.0063 16.4 0.3 0.029 14.3 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 CCF52956.1 - 0.04 13.4 3.5 0.052 13.0 0.3 2.8 3 1 1 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain DUF4426 PF14467.1 CCF52956.1 - 0.12 12.1 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) Myosin_N PF02736.14 CCF52956.1 - 0.36 10.5 2.3 0.39 10.4 0.6 1.8 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF2420 PF10336.4 CCF52957.1 - 1.7e-27 95.2 0.0 3.8e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF4583 PF15190.1 CCF52958.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) Cys_Met_Meta_PP PF01053.15 CCF52960.1 - 1.6e-54 184.6 0.0 6.7e-44 149.7 0.0 2.9 2 2 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme PIF1 PF05970.9 CCF52961.1 - 1.8e-64 217.9 0.8 1.1e-61 208.7 0.5 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCF52961.1 - 1.9e-20 73.2 0.0 4.7e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCF52961.1 - 3.2e-08 33.8 0.0 7.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF52961.1 - 7.6e-06 25.5 0.2 1.8e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCF52961.1 - 2.3e-05 24.4 0.1 6.7e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CCF52961.1 - 0.00017 20.5 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 CCF52961.1 - 0.00029 20.4 0.2 0.029 13.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CCF52961.1 - 0.00043 20.3 0.0 0.002 18.2 0.0 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CCF52961.1 - 0.00048 19.7 0.1 0.072 12.6 0.1 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 CCF52961.1 - 0.00069 19.8 0.0 0.002 18.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCF52961.1 - 0.002 17.1 0.1 0.005 15.8 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CCF52961.1 - 0.0022 17.7 0.3 0.0093 15.6 0.2 2.0 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 CCF52961.1 - 0.0034 17.6 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_14 PF13173.1 CCF52961.1 - 0.0036 17.1 0.0 0.017 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 CCF52961.1 - 0.0048 15.5 0.0 0.0095 14.5 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 CCF52961.1 - 0.0062 15.7 0.1 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCF52961.1 - 0.0076 16.4 0.0 0.052 13.7 0.0 2.4 2 1 0 2 2 2 1 RNA helicase Herpes_Helicase PF02689.9 CCF52961.1 - 0.0096 13.7 0.0 0.097 10.4 0.0 2.1 2 0 0 2 2 2 1 Helicase NACHT PF05729.7 CCF52961.1 - 0.0097 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 CCF52961.1 - 0.012 14.8 0.0 0.04 13.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_32 PF13654.1 CCF52961.1 - 0.014 14.0 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCF52961.1 - 0.019 14.4 0.1 0.064 12.7 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 CCF52961.1 - 0.022 14.4 0.6 0.42 10.3 0.2 2.7 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCF52961.1 - 0.044 13.2 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein UvrD-helicase PF00580.16 CCF52961.1 - 0.045 13.0 0.4 0.096 11.9 0.1 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF815 PF05673.8 CCF52961.1 - 0.056 12.3 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Helicase_RecD PF05127.9 CCF52961.1 - 0.067 12.8 0.3 0.21 11.2 0.2 1.8 1 1 0 1 1 1 0 Helicase MobB PF03205.9 CCF52961.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCF52961.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 CCF52961.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCF52961.1 - 0.093 12.1 0.0 0.37 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CCF52961.1 - 0.097 12.1 0.1 0.25 10.7 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CCF52961.1 - 0.12 11.9 2.5 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain DnaJ-X PF14308.1 CCF52962.1 - 7.8e-57 191.8 0.9 7.8e-57 191.8 0.6 3.0 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCF52962.1 - 1.5e-19 69.4 0.3 1.5e-19 69.4 0.2 2.2 2 1 0 2 2 2 1 DnaJ domain Chon_Sulph_att PF06566.6 CCF52962.1 - 0.023 14.3 0.1 0.023 14.3 0.1 1.8 2 0 0 2 2 2 0 Chondroitin sulphate attachment domain FLO_LFY PF01698.11 CCF52962.1 - 0.11 11.2 8.7 0.22 10.3 6.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein SPX PF03105.14 CCF52962.1 - 2.6 7.7 16.5 4.8 6.8 11.4 1.7 1 1 0 1 1 1 0 SPX domain DUF4407 PF14362.1 CCF52962.1 - 8.9 5.1 15.4 18 4.1 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GATase PF00117.23 CCF52963.1 - 4.5e-05 22.9 0.0 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCF52963.1 - 0.025 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-TFIIIC PF12660.2 CCF52964.1 - 7.5e-14 51.4 2.4 1.7e-13 50.3 1.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 CCF52964.1 - 3.2e-10 39.9 0.1 8.9e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term ThiF PF00899.16 CCF52965.1 - 7.7e-41 139.1 0.1 1.4e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family RabGAP-TBC PF00566.13 CCF52965.1 - 2.5e-33 115.3 0.3 1.8e-16 60.2 0.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MoeZ_MoeB PF05237.8 CCF52965.1 - 1.2e-21 76.1 0.1 3.1e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CCF52965.1 - 4.4e-07 30.2 0.0 3.4e-06 27.3 0.0 2.4 3 0 0 3 3 3 1 Rhodanese-like domain Shikimate_DH PF01488.15 CCF52965.1 - 9.6e-05 22.5 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCF52965.1 - 0.013 15.7 1.0 0.027 14.7 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Saccharop_dh PF03435.13 CCF52965.1 - 0.039 12.9 0.3 0.075 11.9 0.2 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF4604 PF15377.1 CCF52965.1 - 10 6.3 13.5 4.7 7.4 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) YTH PF04146.10 CCF52966.1 - 7.1e-46 155.2 0.0 1.1e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain PapG_N PF03627.8 CCF52966.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain SIS PF01380.17 CCF52967.1 - 2.7e-18 65.8 0.0 8.8e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 CCF52967.1 - 1.8e-07 30.9 0.1 0.0063 16.2 0.0 2.5 1 1 1 2 2 2 2 SIS domain MFS_1 PF07690.11 CCF52968.1 - 5.2e-40 137.2 37.8 5.2e-40 137.2 26.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 CCF52968.1 - 2.5 6.0 12.4 2.2 6.2 3.0 3.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DnaJ PF00226.26 CCF52969.1 - 2.2e-21 75.3 2.3 3.9e-21 74.5 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCF52969.1 - 3.9e-20 71.5 1.9 1.8e-18 66.1 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCF52969.1 - 5e-15 55.2 20.1 8.6e-15 54.5 14.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCF52969.1 - 0.017 14.7 11.0 0.25 11.0 2.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 CCF52969.1 - 3.7 7.3 4.9 4.3 7.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) Peptidase_A22B PF04258.8 CCF52970.1 - 1.9e-71 240.9 7.7 2.3e-71 240.6 5.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 CCF52970.1 - 5.9e-07 28.9 4.6 1.3e-06 27.8 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) FAM176 PF14851.1 CCF52970.1 - 0.0025 17.4 2.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 FAM176 family CENP-B_dimeris PF09026.5 CCF52970.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CCF52970.1 - 5.6 6.4 9.0 7.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin FAD_binding_8 PF08022.7 CCF52971.1 - 8.1e-17 61.0 0.0 7.5e-16 57.9 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 CCF52971.1 - 1.8e-13 50.6 9.3 4.8e-13 49.2 6.5 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCF52971.1 - 6.3e-13 48.9 0.0 4.5e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Gpi16 PF04113.9 CCF52972.1 - 2.4e-103 346.1 0.0 9.5e-86 288.0 0.0 3.2 2 1 0 2 2 2 2 Gpi16 subunit, GPI transamidase component Mito_fiss_reg PF05308.6 CCF52972.1 - 0.0074 15.6 2.3 0.014 14.8 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 CCF52972.1 - 0.028 13.7 3.5 0.05 12.8 2.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4344 PF14247.1 CCF52972.1 - 0.11 12.1 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) zf-met2 PF12907.2 CCF52973.1 - 1.4e-09 37.7 1.1 2.2e-09 37.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CCF52973.1 - 7.7e-08 32.9 14.6 1e-07 32.5 10.1 1.2 1 0 0 1 1 1 1 4F5 protein family Eapp_C PF10238.4 CCF52973.1 - 0.067 13.0 0.7 0.083 12.7 0.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein SMI1_KNR4 PF09346.5 CCF52974.1 - 2.5e-31 108.3 0.0 3.9e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Glyco_hydro_25 PF01183.15 CCF52975.1 - 1e-42 145.9 0.9 1.3e-42 145.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Herpes_UL42 PF02282.11 CCF52975.1 - 0.023 14.2 0.1 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 DNA polymerase processivity factor (UL42) Glyco_hydro_63 PF03200.11 CCF52976.1 - 8.1e-235 781.3 0.0 5.5e-234 778.6 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 CCF52976.1 - 3.2e-09 35.9 0.1 5.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 CCF52976.1 - 0.0086 14.3 0.0 0.015 13.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase XPA_C PF05181.7 CCF52977.1 - 3e-27 93.9 2.1 5.7e-27 93.0 1.5 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Mitochondr_Som1 PF11093.3 CCF52977.1 - 0.035 13.9 0.5 0.077 12.8 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial export protein Som1 zinc_ribbon_2 PF13240.1 CCF52977.1 - 1.3 8.5 4.5 8.2 6.0 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain XPA_N PF01286.13 CCF52977.1 - 5.3 6.8 6.3 0.97 9.1 1.5 1.9 2 1 0 2 2 2 0 XPA protein N-terminal Sec16_C PF12931.2 CCF52978.1 - 6.5e-86 288.5 0.0 9.5e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCF52978.1 - 1.2e-31 109.0 0.0 2.8e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region zf-RING_UBOX PF13445.1 CCF52979.1 - 2.8e-17 62.1 0.8 6e-17 61.0 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CCF52979.1 - 1.2e-15 57.5 0.0 2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-C3HC4_4 PF15227.1 CCF52979.1 - 1.6e-05 24.6 0.5 3.3e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCF52979.1 - 2.2e-05 24.0 0.8 3.7e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCF52979.1 - 0.00044 20.0 0.7 0.00071 19.3 0.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCF52979.1 - 0.00049 19.7 0.6 0.00079 19.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF52979.1 - 0.00098 19.1 1.5 0.0016 18.4 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF52979.1 - 0.0036 16.9 1.2 0.0063 16.1 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CCF52979.1 - 0.049 12.8 0.8 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger zf-MIZ PF02891.15 CCF52979.1 - 0.11 12.0 0.3 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RVT_2 PF07727.9 CCF52980.1 - 2.7e-22 78.9 0.0 4e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Metallophos PF00149.23 CCF52981.1 - 1.3e-08 34.5 2.6 3.5e-08 33.0 1.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCF52981.1 - 9.1e-06 25.5 0.4 2.5e-05 24.1 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RHD3 PF05879.7 CCF52982.1 - 5.9e-249 827.9 1.1 7.5e-249 827.5 0.8 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CCF52982.1 - 3.6e-08 32.7 0.1 1.3e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CCF52982.1 - 5e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCF52982.1 - 5e-05 23.1 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CCF52982.1 - 0.00011 22.6 0.3 0.00034 21.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CCF52982.1 - 0.0078 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SLY PF12485.3 CCF52982.1 - 0.022 14.9 0.2 0.061 13.5 0.2 1.8 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Ras PF00071.17 CCF52982.1 - 0.061 12.7 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras family WD40 PF00400.27 CCF52983.1 - 7.5e-20 70.0 17.7 0.00023 20.8 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat NLE PF08154.7 CCF52983.1 - 3.4e-16 58.9 0.0 6.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain DUF3565 PF12088.3 CCF52983.1 - 0.77 9.5 3.0 0.33 10.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Yippee-Mis18 PF03226.9 CCF52984.1 - 1.3e-15 57.2 1.0 1.6e-15 56.9 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DNA_RNApol_7kD PF03604.8 CCF52984.1 - 0.21 11.0 1.3 0.48 9.9 0.1 2.1 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SKG6 PF08693.5 CCF52985.1 - 1.8e-08 33.5 0.1 5.9e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 CCF52985.1 - 0.017 14.8 0.5 0.078 12.6 0.2 2.4 2 1 0 2 2 2 0 TMEM154 protein family DUF4448 PF14610.1 CCF52985.1 - 0.021 14.3 0.1 0.052 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1191 PF06697.7 CCF52985.1 - 0.047 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF912 PF06024.7 CCF52985.1 - 3.7 7.6 5.0 1.1 9.3 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HAMP PF00672.20 CCF52986.1 - 1.1e-46 156.8 19.6 2e-08 34.2 0.3 8.1 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 CCF52986.1 - 1.6e-27 95.3 0.1 5.6e-27 93.6 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCF52986.1 - 3.9e-26 91.2 0.7 4.7e-24 84.5 0.5 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 CCF52986.1 - 5.4e-17 61.5 0.3 3.9e-16 58.8 0.2 2.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 CCF52986.1 - 0.023 14.4 0.1 0.42 10.5 0.0 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Syntaxin PF00804.20 CCF52986.1 - 0.072 13.2 5.1 10 6.3 0.7 5.0 4 2 0 4 4 4 0 Syntaxin DUF2365 PF10157.4 CCF52986.1 - 0.092 12.6 10.2 45 3.9 0.1 6.4 6 2 1 7 7 7 0 Uncharacterized conserved protein (DUF2365) eIF-5_eIF-2B PF01873.12 CCF52986.1 - 0.17 11.5 2.8 49 3.5 0.0 4.7 7 0 0 7 7 7 0 Domain found in IF2B/IF5 Glyco_hydro_31 PF01055.21 CCF52987.1 - 2e-156 521.2 4.4 2.7e-156 520.8 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Pkinase PF00069.20 CCF52988.1 - 8.7e-55 185.6 0.2 2.8e-35 121.7 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52988.1 - 2.9e-24 85.5 0.3 9.8e-17 60.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3439 PF11921.3 CCF52988.1 - 0.0043 16.7 3.5 0.0088 15.7 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Kinase-like PF14531.1 CCF52988.1 - 0.0072 15.3 0.0 0.033 13.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCF52988.1 - 0.011 15.5 1.1 0.12 12.1 0.1 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family SSP160 PF06933.6 CCF52988.1 - 0.19 9.7 7.5 0.28 9.1 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PhyH PF05721.8 CCF52990.1 - 3.8e-45 154.5 0.0 5.2e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 CCF52990.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase OPT PF03169.10 CCF52991.1 - 9.9e-146 486.7 10.8 1.1e-145 486.5 7.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Topoisom_bac PF01131.15 CCF52992.1 - 1.8e-89 300.3 0.0 2.2e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 CCF52992.1 - 2.6e-24 84.8 10.5 2.7e-13 49.6 1.4 2.9 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.17 CCF52992.1 - 1e-19 70.3 0.0 3.5e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.18 CCF52992.1 - 1.2e-13 50.2 15.7 1.9e-07 30.6 2.2 3.0 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CCF52992.1 - 2.6e-07 30.2 4.6 0.0015 18.1 0.2 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.1 CCF52992.1 - 0.00064 19.1 13.7 0.062 12.8 1.9 2.7 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 CCF52992.1 - 0.045 13.2 6.1 0.068 12.6 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CCF52992.1 - 0.053 13.4 1.8 6.1 6.7 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 CCF52992.1 - 0.97 9.1 7.0 7.1 6.3 0.3 2.6 2 0 0 2 2 2 0 Zinc knuckle HLH PF00010.21 CCF52993.1 - 3.7e-09 36.1 0.0 1.2e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Inositol_P PF00459.20 CCF52994.1 - 5.1e-68 229.3 0.1 6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Dicty_REP PF05086.7 CCF52995.1 - 1.3 6.6 4.3 2.1 5.9 3.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 CCF52996.1 - 1.1e-20 73.9 0.0 6.3e-19 68.1 0.0 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF52996.1 - 1.3e-07 31.0 0.0 6.7e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCF52996.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCF52996.1 - 0.0071 15.2 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 CCF52996.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCF52996.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 CCF52996.1 - 0.3 10.2 0.1 0.46 9.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Caleosin PF05042.8 CCF52997.1 - 7.4e-50 168.9 0.0 9.6e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Ras PF00071.17 CCF52998.1 - 1e-20 73.7 0.0 1.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF52998.1 - 8.4e-13 48.8 0.1 2.3e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CCF52998.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region KAP_NTPase PF07693.9 CCF52998.1 - 0.0043 16.0 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 CCF52998.1 - 0.0055 16.8 0.1 0.02 15.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCF52998.1 - 0.0089 15.6 0.1 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 CCF52998.1 - 0.0091 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CCF52998.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CCF52998.1 - 0.0094 15.0 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2791 PF10923.3 CCF52998.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_17 PF13207.1 CCF52998.1 - 0.012 16.4 0.2 0.027 15.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCF52998.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CCF52998.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CCF52998.1 - 0.022 14.2 0.2 0.04 13.4 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 CCF52998.1 - 0.022 14.3 0.2 0.037 13.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCF52998.1 - 0.025 14.8 0.4 0.096 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CCF52998.1 - 0.028 13.6 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ATP_bind_1 PF03029.12 CCF52998.1 - 0.035 13.6 0.1 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 CCF52998.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.1 CCF52998.1 - 0.068 13.4 3.0 1.3 9.3 2.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCF52998.1 - 0.078 12.3 0.2 0.14 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCF52998.1 - 0.094 12.2 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 CCF52998.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain KTI12 PF08433.5 CCF52998.1 - 0.13 11.4 0.6 0.79 8.8 0.1 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 HbrB PF08539.6 CCF52999.1 - 3e-46 157.1 0.0 4.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 HbrB-like His_Phos_1 PF00300.17 CCF52999.1 - 1.5e-30 106.3 0.0 2.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_18 PF00704.23 CCF53000.1 - 1.6e-12 47.5 0.3 2.2e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Phage_CI_repr PF07022.8 CCF53000.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain DNA_pol_E_B PF04042.11 CCF53001.1 - 5.6e-44 149.8 0.1 8.6e-44 149.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ADH_zinc_N PF00107.21 CCF53002.1 - 8.3e-06 25.3 0.0 9.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DNase_NucA_NucB PF14040.1 CCF53003.1 - 2e-27 95.5 1.7 3.3e-27 94.8 1.2 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB OPT PF03169.10 CCF53004.1 - 3.5e-96 323.0 44.3 5.4e-96 322.4 30.7 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein TMEM125 PF15109.1 CCF53004.1 - 0.12 12.5 2.0 8 6.6 0.0 2.8 2 0 0 2 2 2 0 TMEM125 protein family Fungal_trans_2 PF11951.3 CCF53006.1 - 9e-14 50.8 0.0 1.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2678 PF10856.3 CCF53006.1 - 0.03 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Aldedh PF00171.17 CCF53007.1 - 6.4e-181 601.7 0.2 7.2e-181 601.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF53007.1 - 0.001 17.9 0.0 0.0019 16.9 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) UDG PF03167.14 CCF53008.1 - 4.5e-23 81.4 0.1 5.5e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily RVT_2 PF07727.9 CCF53009.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF953 PF06110.6 CCF53010.1 - 4.1e-16 58.5 0.0 4.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 CCF53010.1 - 0.00019 21.0 0.5 0.00031 20.3 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CCF53010.1 - 0.0004 19.9 0.0 0.00046 19.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CCF53010.1 - 0.0011 18.7 0.2 0.0031 17.2 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CCF53010.1 - 0.0081 16.3 0.3 0.025 14.7 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF53010.1 - 0.12 12.5 0.1 5.8 7.1 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Plasmodium_Vir PF05795.6 CCF53012.1 - 0.16 11.1 0.2 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein COPI_assoc PF08507.5 CCF53012.1 - 1.6 8.4 5.9 2 8.0 3.3 1.7 2 0 0 2 2 2 0 COPI associated protein R3H-assoc PF13902.1 CCF53013.1 - 0.0025 17.7 0.1 0.0025 17.7 0.1 2.8 3 0 0 3 3 3 1 R3H-associated N-terminal domain Ribosomal_L6 PF00347.18 CCF53014.1 - 2.7e-23 82.2 0.0 5.3e-13 49.2 0.0 2.7 3 0 0 3 3 3 2 Ribosomal protein L6 DUF4626 PF15422.1 CCF53014.1 - 0.61 10.0 3.5 41 4.1 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4626) Ribosomal_L34e PF01199.13 CCF53015.1 - 6.9e-36 122.3 4.2 8.6e-36 122.0 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 CCF53015.1 - 0.022 14.3 0.2 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c7 AOX PF01786.12 CCF53016.1 - 7.4e-91 303.1 0.1 8.9e-91 302.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase NDT80_PhoG PF05224.7 CCF53017.1 - 1.5e-19 70.7 0.0 4.2e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family BSP_II PF05432.6 CCF53017.1 - 0.0033 16.7 6.6 0.0033 16.7 4.6 2.5 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 CCF53017.1 - 0.046 13.2 2.6 0.097 12.1 1.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CCF53017.1 - 0.06 13.5 7.3 0.14 12.3 5.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NDK PF00334.14 CCF53018.1 - 3.9e-56 188.5 0.0 4.5e-56 188.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.27 CCF53019.1 - 1.6e-32 110.1 16.1 4.4e-09 35.8 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat IKI3 PF04762.7 CCF53019.1 - 0.14 9.9 0.0 0.48 8.1 0.0 1.8 1 1 0 1 1 1 0 IKI3 family Transket_pyr PF02779.19 CCF53020.1 - 5.3e-33 113.9 0.1 1.5e-32 112.5 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCF53020.1 - 1.2e-27 96.3 0.0 4.9e-27 94.3 0.0 1.9 1 1 0 1 1 1 1 Transketolase, C-terminal domain Aldo_ket_red PF00248.16 CCF53021.1 - 2.7e-57 193.7 0.0 4e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L10 PF00466.15 CCF53021.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 IDO PF01231.13 CCF53022.1 - 0.0015 17.0 0.0 0.02 13.3 0.0 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF3089 PF11288.3 CCF53022.1 - 0.0016 17.6 0.5 0.0029 16.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) SEN1_N PF12726.2 CCF53023.1 - 1.9e-132 442.8 4.5 2.7e-132 442.3 3.1 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CCF53023.1 - 4.5e-67 226.0 0.2 4.5e-67 226.0 0.1 3.7 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 CCF53023.1 - 3.7e-62 209.2 0.0 1e-61 207.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF53023.1 - 2.1e-11 43.3 1.1 1.1e-10 41.1 0.7 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCF53023.1 - 0.0011 18.4 0.1 0.003 16.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 CCF53023.1 - 0.0068 16.5 0.9 0.024 14.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 CCF53023.1 - 0.42 10.7 4.0 7.9 6.6 0.1 3.9 4 0 0 4 4 4 0 AAA domain Activator_LAG-3 PF11498.3 CCF53023.1 - 2.8 6.6 41.4 0.12 11.1 21.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 vATP-synt_AC39 PF01992.11 CCF53024.1 - 3.5e-95 318.9 0.0 3.9e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit RVT_1 PF00078.22 CCF53025.1 - 9.3e-20 70.8 0.1 9e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CCF53025.1 - 3.4e-06 26.7 4.7 7.4e-06 25.6 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CCF53025.1 - 0.00044 20.2 0.3 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CCF53025.1 - 0.014 14.8 1.5 0.036 13.5 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 CCF53026.1 - 1.2e-21 76.9 0.0 8.4e-21 74.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CCF53026.1 - 6.6e-07 28.7 0.1 3.9e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 CCF53026.1 - 3.2e-05 23.6 0.6 0.0001 22.0 0.4 2.0 1 0 0 1 1 1 1 Zinc knuckle Aminotran_4 PF01063.14 CCF53027.1 - 1.1e-12 47.9 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Trs65 PF12735.2 CCF53028.1 - 4.5e-06 26.2 0.2 0.041 13.1 0.0 2.9 2 1 0 2 2 2 2 TRAPP trafficking subunit Trs65 CPSF_A PF03178.10 CCF53029.1 - 1.2e-42 146.1 0.0 2.5e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CCF53029.1 - 1.8e-30 105.5 0.0 3.8e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term AA_permease_2 PF13520.1 CCF53030.1 - 2.6e-45 154.7 44.7 3.6e-45 154.2 31.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF53030.1 - 2.2e-20 72.4 46.8 4.8e-20 71.3 32.4 1.5 1 1 0 1 1 1 1 Amino acid permease PALP PF00291.20 CCF53031.1 - 4.6e-53 180.4 0.0 2.1e-52 178.2 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Dimerisation PF08100.6 CCF53031.1 - 0.022 14.5 0.0 0.7 9.7 0.1 2.6 2 0 0 2 2 2 0 Dimerisation domain DUF221 PF02714.10 CCF53032.1 - 1.2e-43 149.2 21.8 2.1e-43 148.4 15.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCF53032.1 - 6.7e-15 54.9 0.9 6.7e-15 54.9 0.6 2.9 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport RRM_6 PF14259.1 CCF53032.1 - 0.028 14.4 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4463 PF14703.1 CCF53032.1 - 0.039 14.4 0.3 0.039 14.4 0.2 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4463) ABC2_membrane PF01061.19 CCF53033.1 - 1.8e-73 246.1 67.9 4.4e-39 133.8 21.8 2.8 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCF53033.1 - 1e-35 123.0 1.1 1.2e-18 67.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 CCF53033.1 - 2.7e-29 100.8 0.1 1.8e-23 82.1 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCF53033.1 - 4.6e-10 39.4 0.2 1.1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCF53033.1 - 5.5e-09 35.5 50.2 8.6e-05 21.7 14.7 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 CCF53033.1 - 1.9e-05 23.9 0.6 0.0015 17.7 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CCF53033.1 - 3.3e-05 23.2 0.0 0.00011 21.4 0.0 1.9 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCF53033.1 - 0.00017 21.0 0.4 0.0047 16.4 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCF53033.1 - 0.00027 20.3 0.1 0.068 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCF53033.1 - 0.0004 20.5 0.0 0.07 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCF53033.1 - 0.00072 19.4 0.0 0.29 11.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.14 CCF53033.1 - 0.0022 17.4 0.0 0.0055 16.1 0.0 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 CCF53033.1 - 0.0051 17.6 0.0 0.13 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCF53033.1 - 0.0054 16.7 0.0 0.14 12.1 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCF53033.1 - 0.024 14.5 0.0 1.6 8.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCF53033.1 - 0.026 14.5 0.2 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 CCF53033.1 - 0.032 13.8 0.5 0.48 10.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CCF53033.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CCF53033.1 - 0.11 13.0 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 CCF53033.1 - 0.16 12.3 0.0 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCF53033.1 - 0.16 11.4 0.1 1.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 CCF53033.1 - 0.47 9.4 0.0 0.92 8.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3505 PF12013.3 CCF53035.1 - 0.024 14.8 3.4 0.11 12.7 2.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) DUF1764 PF08576.5 CCF53036.1 - 3e-16 60.0 0.4 3e-16 60.0 0.3 2.5 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) BLVR PF06375.6 CCF53036.1 - 0.045 13.5 3.7 0.062 13.1 2.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF755 PF05501.6 CCF53036.1 - 0.31 11.1 7.2 0.51 10.4 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF936 PF06075.7 CCF53036.1 - 1.2 8.0 8.4 1.3 7.8 5.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SRP-alpha_N PF04086.8 CCF53036.1 - 1.6 8.0 7.4 1.8 7.8 5.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal VCX_VCY PF15231.1 CCF53036.1 - 2.9 8.2 15.4 1.7 9.0 7.6 2.2 2 0 0 2 2 2 0 Variable charge X/Y family Pol_alpha_B_N PF08418.5 CCF53036.1 - 6.6 6.1 8.1 9.1 5.7 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PS_Dcarbxylase PF02666.10 CCF53037.1 - 2.8e-49 167.1 0.0 4.3e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CCF53037.1 - 4.6e-32 109.7 0.1 2.7e-14 52.7 0.0 3.7 3 0 0 3 3 3 3 C2 domain SDA1 PF05285.7 CCF53037.1 - 0.05 12.8 13.7 0.079 12.2 9.5 1.2 1 0 0 1 1 1 0 SDA1 CEP76-C2 PF15627.1 CCF53037.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 CEP76 C2 domain BUD22 PF09073.5 CCF53037.1 - 4.6 6.2 15.5 8.5 5.3 10.8 1.3 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.7 CCF53037.1 - 6.1 4.8 5.8 9 4.2 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Daxx PF03344.10 CCF53037.1 - 6.4 5.1 23.5 0.0026 16.3 5.5 2.1 2 0 0 2 2 2 0 Daxx Family B12D PF06522.6 CCF53038.1 - 2.3e-19 68.8 0.1 3e-19 68.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit ELFV_dehydrog PF00208.16 CCF53039.1 - 1.4e-25 90.2 0.9 4.4e-25 88.6 0.3 1.8 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Fe_hyd_lg_C PF02906.9 CCF53040.1 - 1.5e-57 195.0 0.0 2.3e-56 191.1 0.0 2.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain GldH_lipo PF14109.1 CCF53040.1 - 0.023 14.9 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 GldH lipoprotein Microcin PF03526.8 CCF53040.1 - 0.096 12.2 0.4 0.21 11.2 0.3 1.5 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Ribosomal_60s PF00428.14 CCF53040.1 - 1 9.7 13.4 1 9.7 1.6 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Glyco_tranf_2_3 PF13641.1 CCF53041.1 - 4.2e-21 75.8 0.0 5.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCF53041.1 - 2.8e-16 59.7 2.3 2.8e-16 59.7 1.6 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 CCF53041.1 - 3.8e-07 29.9 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCF53041.1 - 1.4e-06 27.7 0.0 2.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 CoA_binding PF02629.14 CCF53042.1 - 6e-21 74.7 0.8 1.2e-20 73.7 0.6 1.5 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 CCF53042.1 - 4.7e-12 45.7 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCF53042.1 - 0.00033 20.2 0.0 0.00083 18.9 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.17 CCF53042.1 - 0.00042 20.8 0.1 0.00083 19.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ligase_CoA PF00549.14 CCF53043.1 - 1.5e-12 47.3 0.7 2.3e-12 46.7 0.5 1.2 1 0 0 1 1 1 1 CoA-ligase Ribosomal_S11 PF00411.14 CCF53043.1 - 0.057 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S11 Peptidase_C12 PF01088.16 CCF53044.1 - 1.1e-57 194.6 0.0 1.3e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med10 PF09748.4 CCF53045.1 - 1.4e-21 76.6 0.1 1.9e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2236 PF09995.4 CCF53046.1 - 1.1e-16 60.9 0.0 2.4e-16 59.7 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CBFD_NFYB_HMF PF00808.18 CCF53047.1 - 2.4e-19 69.1 0.5 3.4e-19 68.6 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF53047.1 - 7.1e-10 38.8 0.1 1.2e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 tRNA-synt_2 PF00152.15 CCF53048.1 - 6.4e-74 248.7 0.0 1.2e-73 247.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 CCF53048.1 - 1.6e-17 63.2 0.1 2.5e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 CCF53048.1 - 6.8e-07 29.0 0.1 1.7e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCF53048.1 - 0.013 14.7 0.1 6 5.9 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) SAGA-Tad1 PF12767.2 CCF53048.1 - 0.77 9.3 5.0 0.79 9.3 2.5 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit His_Phos_1 PF00300.17 CCF53049.1 - 1.7e-17 63.9 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_zinc_N PF00107.21 CCF53050.1 - 1.6e-25 89.1 0.0 3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF53050.1 - 2.5e-08 34.8 0.0 4.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CCF53050.1 - 0.0038 16.8 0.2 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AFOR_C PF01314.13 CCF53050.1 - 0.096 11.3 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DUF500 PF04366.7 CCF53051.1 - 2.8e-31 107.5 0.0 4.9e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) HAD PF12710.2 CCF53051.1 - 8.1e-10 39.1 0.2 2.6e-09 37.5 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIRA_B PF09453.5 CCF53051.1 - 0.35 10.4 2.1 0.86 9.2 1.5 1.6 1 0 0 1 1 1 0 HIRA B motif Phasin PF05597.6 CCF53053.1 - 0.041 13.6 0.0 0.056 13.1 0.0 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ECH PF00378.15 CCF53054.1 - 1.2e-39 135.8 0.0 1.9e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pterin_4a PF01329.14 CCF53054.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase PWI PF01480.12 CCF53055.1 - 8.7e-29 99.4 0.0 1.4e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain Methyltransf_18 PF12847.2 CCF53056.1 - 8.4e-05 23.1 0.0 0.00012 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF53056.1 - 0.0004 20.0 0.0 0.0022 17.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Borrelia_P83 PF05262.6 CCF53057.1 - 0.065 11.5 11.0 0.077 11.2 7.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RNase_H2-Ydr279 PF09468.5 CCF53057.1 - 0.14 11.3 7.6 0.24 10.5 5.2 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 CCF53057.1 - 0.24 11.3 5.3 0.36 10.7 3.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3807 PF12720.2 CCF53057.1 - 0.26 11.4 11.8 0.55 10.3 8.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Ycf1 PF05758.7 CCF53057.1 - 0.37 8.4 3.7 0.41 8.2 2.6 1.1 1 0 0 1 1 1 0 Ycf1 U79_P34 PF03064.11 CCF53057.1 - 0.44 10.0 11.7 0.74 9.2 8.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SAPS PF04499.10 CCF53057.1 - 0.49 8.9 3.5 0.58 8.7 2.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FLO_LFY PF01698.11 CCF53057.1 - 0.67 8.7 8.2 1.2 7.8 5.7 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 CCF53057.1 - 1.5 7.5 15.9 2.5 6.7 11.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APG6 PF04111.7 CCF53057.1 - 3.2 6.7 12.4 5.4 5.9 8.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 CCF53057.1 - 5.2 4.6 5.8 6.7 4.2 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1682 PF07946.9 CCF53057.1 - 7 5.4 16.0 10 4.8 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pex14_N PF04695.8 CCF53058.1 - 0.01 15.9 0.3 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRP1_N PF06424.7 CCF53058.1 - 0.038 14.3 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GlutR_dimer PF00745.15 CCF53058.1 - 0.058 13.3 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain dCMP_cyt_deam_1 PF00383.17 CCF53059.1 - 2.3e-15 56.0 0.2 4.7e-15 55.0 0.1 1.5 1 1 1 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CCF53059.1 - 1.9e-11 44.0 0.7 9.9e-10 38.4 0.0 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CCF53059.1 - 0.0013 18.1 1.5 0.011 15.1 0.0 2.3 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases MFS_1 PF07690.11 CCF53061.1 - 1.5e-17 63.3 24.8 1.5e-11 43.6 10.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF427 PF04248.7 CCF53061.1 - 3.1e-15 55.6 0.1 6.2e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) ATG22 PF11700.3 CCF53061.1 - 4.1e-07 28.8 7.5 4.1e-07 28.8 5.2 2.7 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like Na_H_Exchanger PF00999.16 CCF53062.1 - 2e-50 171.4 17.1 2.6e-50 171.0 11.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 CCF53062.1 - 0.0066 16.3 1.1 0.069 13.0 0.0 2.8 3 0 0 3 3 3 1 YrhC-like protein FGGY_C PF02782.11 CCF53063.1 - 8.9e-16 58.0 0.0 1.8e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCF53063.1 - 5.5e-11 42.2 0.0 5.6e-07 29.1 0.0 3.2 2 1 1 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain NMO PF03060.10 CCF53064.1 - 7.9e-51 173.1 0.6 2.4e-50 171.5 0.4 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase CoA_transf_3 PF02515.12 CCF53065.1 - 2e-64 216.3 0.3 2.9e-64 215.8 0.2 1.3 1 0 0 1 1 1 1 CoA-transferase family III Got1 PF04178.7 CCF53066.1 - 1.1e-19 70.6 25.6 1.5e-19 70.2 17.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family CorC_HlyC PF03471.12 CCF53066.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Transporter associated domain DUF1914 PF08932.5 CCF53066.1 - 0.61 10.1 3.0 5.7 6.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1914) Zn_clus PF00172.13 CCF53067.1 - 0.00019 21.2 11.3 0.00038 20.2 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Borrelia_P83 PF05262.6 CCF53067.1 - 0.00062 18.1 4.0 0.00087 17.6 2.8 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein PAS_9 PF13426.1 CCF53067.1 - 0.0026 18.1 0.0 0.0099 16.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 CCF53067.1 - 0.0038 16.9 0.6 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold LIM_bind PF01803.11 CCF53067.1 - 0.12 11.4 9.7 1.9 7.5 0.0 2.5 2 0 0 2 2 2 0 LIM-domain binding protein DUF4407 PF14362.1 CCF53067.1 - 3 6.7 13.3 5.7 5.7 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AA_permease_2 PF13520.1 CCF53068.1 - 0.031 12.8 0.2 0.031 12.8 0.1 1.4 2 0 0 2 2 2 0 Amino acid permease Allantoicase PF03561.10 CCF53069.1 - 1.1e-84 281.4 0.0 1.1e-43 148.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 CCF53069.1 - 7.3e-47 158.7 0.1 1.1e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate hydrolase PAF-AH_p_II PF03403.8 CCF53070.1 - 2.9e-47 160.7 0.0 9.2e-45 152.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CCF53070.1 - 7e-10 38.8 0.1 3.3e-09 36.6 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family HAD_2 PF13419.1 CCF53070.1 - 3.5e-09 37.1 0.0 6.3e-08 33.0 0.0 2.5 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 CCF53070.1 - 6.1e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2229 PF09989.4 CCF53070.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Esterase PF00756.15 CCF53070.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 CCF53070.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 CCF53070.1 - 0.21 10.4 0.0 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF3307 PF11750.3 CCF53072.1 - 0.12 12.0 1.1 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) SNARE PF05739.14 CCF53074.1 - 2.5e-10 39.8 4.5 3.7e-10 39.3 3.1 1.3 1 0 0 1 1 1 1 SNARE domain MIP PF00230.15 CCF53076.1 - 7.8e-43 146.5 3.9 1.1e-42 146.1 2.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein DNA_pol_B PF00136.16 CCF53077.1 - 1.3e-91 307.7 0.0 1.8e-91 307.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCF53077.1 - 6.3e-22 77.8 0.0 4.2e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCF53077.1 - 3.8e-11 42.8 7.3 7.4e-11 41.8 5.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MutL_C PF08676.6 CCF53078.1 - 7.7e-22 77.4 0.0 1.9e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CCF53078.1 - 4e-20 71.4 0.0 8.9e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCF53078.1 - 7e-13 48.4 0.2 2.8e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCF53078.1 - 5.7e-11 42.1 0.0 1.8e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MAD PF05557.8 CCF53079.1 - 0.017 13.2 0.6 0.022 12.8 0.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3585 PF12130.3 CCF53079.1 - 0.068 13.0 4.7 0.45 10.3 3.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3585) HGTP_anticodon2 PF12745.2 CCF53079.1 - 0.098 11.7 1.8 0.12 11.4 1.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ERM PF00769.14 CCF53079.1 - 0.15 11.5 3.5 0.2 11.1 2.4 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.10 CCF53079.1 - 0.75 9.3 3.7 0.98 8.9 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator PBP1_TM PF14812.1 CCF53079.1 - 1.4 9.3 5.0 0.32 11.3 0.7 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IncA PF04156.9 CCF53079.1 - 3.5 7.1 5.8 8 6.0 0.5 2.0 1 1 1 2 2 2 0 IncA protein ERG2_Sigma1R PF04622.7 CCF53080.1 - 8.1e-97 322.6 0.1 9.4e-97 322.4 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Rhodanese PF00581.15 CCF53081.1 - 6.4e-10 39.3 0.0 1.4e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain PilM PF07419.7 CCF53081.1 - 0.1 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 PilM ECH PF00378.15 CCF53082.1 - 9.3e-53 178.8 0.0 1.2e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding PF00501.23 CCF53083.1 - 7.1e-77 258.5 0.1 1.7e-49 168.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CCF53083.1 - 9.1e-09 36.1 0.0 2.3e-07 31.6 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.23 CCF53084.1 - 4.1e-07 29.5 3.3 4.1e-07 29.5 2.3 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCF53084.1 - 0.00038 20.3 0.2 0.0023 17.7 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Abhydrolase_6 PF12697.2 CCF53085.1 - 1e-16 61.5 0.0 2.4e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF53085.1 - 0.0025 17.6 0.0 0.0062 16.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CUE PF02845.11 CCF53086.1 - 3.7e-11 42.2 0.0 6.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain BioT2 PF15368.1 CCF53086.1 - 0.043 13.5 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 Med13_C PF06333.7 CCF53086.1 - 0.12 10.8 1.2 0.15 10.5 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Ribosomal_L37 PF08561.5 CCF53087.1 - 1.9e-29 101.0 8.7 1.5e-27 95.0 6.0 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Peptidase_M19 PF01244.16 CCF53089.1 - 1.2e-86 290.6 0.0 1.4e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Glyco_hydro_31 PF01055.21 CCF53090.1 - 2.8e-79 267.0 0.1 3.5e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCF53090.1 - 4.6e-08 32.8 0.0 1.7e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like MFS_1 PF07690.11 CCF53091.1 - 4.4e-35 121.0 21.3 5.9e-35 120.6 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 CCF53092.1 - 4e-87 292.4 5.7 5.8e-87 291.9 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CCF53092.1 - 3.6e-06 27.2 0.0 1.2e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PXA PF02194.10 CCF53094.1 - 2.7e-19 69.4 0.9 1.7e-17 63.5 0.2 2.8 3 0 0 3 3 3 2 PXA domain Nexin_C PF08628.7 CCF53094.1 - 0.0021 18.1 0.0 0.0086 16.1 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal peroxidase PF00141.18 CCF53096.1 - 8.4e-50 169.3 0.0 1.2e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MotB_plug PF13677.1 CCF53096.1 - 0.13 11.6 0.1 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Glyco_hydro_88 PF07470.8 CCF53099.1 - 3.5e-75 253.1 1.7 4.9e-75 252.6 1.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Acetyltransf_3 PF13302.1 CCF53100.1 - 1.3e-13 51.2 0.0 2.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF53100.1 - 7.9e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCF53100.1 - 0.00016 21.6 0.1 0.00028 20.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF53100.1 - 0.014 15.2 0.1 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UvdE PF03851.9 CCF53101.1 - 2.4e-85 285.9 0.0 3.2e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE RCC1 PF00415.13 CCF53102.1 - 3.7e-23 81.4 14.4 1.5e-10 41.0 0.0 8.7 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCF53102.1 - 4.6e-12 45.2 10.3 2.3e-08 33.4 0.2 6.3 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat N6-adenineMlase PF10237.4 CCF53103.1 - 5.4e-28 97.6 0.0 1.2e-27 96.5 0.0 1.5 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 CCF53103.1 - 0.043 13.8 0.1 0.087 12.8 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF4228 PF14009.1 CCF53103.1 - 0.18 11.8 5.3 0.29 11.2 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) 4HBT PF03061.17 CCF53104.1 - 2.6e-12 46.6 0.0 4.7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PRELI PF04707.9 CCF53105.1 - 2.8e-38 130.9 0.0 3.4e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Glyco_hydro_47 PF01532.15 CCF53106.1 - 2.8e-123 411.9 0.0 3.2e-123 411.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 CCF53106.1 - 0.00014 21.3 0.1 0.0086 15.4 0.0 2.7 2 1 1 3 3 3 1 Glycosyl hydrolase family 76 WES_acyltransf PF03007.11 CCF53109.1 - 1.6e-13 50.8 0.0 4.8e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 CCF53109.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Mrr_cat_2 PF13156.1 CCF53109.1 - 0.044 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease DSBA PF01323.15 CCF53110.1 - 9.7e-13 48.1 0.6 9.1e-11 41.6 0.4 2.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Fungal_trans_2 PF11951.3 CCF53111.1 - 1.4e-13 50.2 0.1 1.6e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53111.1 - 1.3e-09 37.8 11.6 2e-09 37.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RP-C_C PF11800.3 CCF53112.1 - 0.028 14.1 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region GalKase_gal_bdg PF10509.4 CCF53113.1 - 5e-21 73.7 0.1 1.2e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCF53113.1 - 2.4e-11 43.5 0.2 7.1e-11 42.0 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCF53113.1 - 8.3e-10 38.7 0.1 2.7e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Fungal_trans PF04082.13 CCF53114.1 - 4.7e-06 25.6 0.2 8.3e-06 24.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53114.1 - 1.5e-05 24.7 11.1 3.2e-05 23.7 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CCF53115.1 - 1.2e-37 129.4 50.0 1.4e-36 125.9 34.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF53115.1 - 1.2e-10 40.5 14.0 1.2e-10 40.5 9.7 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCF53115.1 - 9.4e-05 20.7 11.5 0.00014 20.2 8.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 CCF53116.1 - 1.1e-137 458.9 6.0 1.4e-137 458.6 4.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_2 PF13347.1 CCF53116.1 - 0.00032 19.2 10.1 0.0053 15.1 7.0 2.1 1 1 0 1 1 1 1 MFS/sugar transport protein UCR_Fe-S_N PF10399.4 CCF53116.1 - 0.15 11.2 1.2 0.39 9.9 0.9 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ACOX PF01756.14 CCF53117.1 - 4.1e-19 68.6 0.0 1.3e-17 63.7 0.0 2.7 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CCF53117.1 - 5e-19 68.8 0.2 1e-18 67.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 CCF53117.1 - 3.3e-09 36.1 0.6 1e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CCF53117.1 - 1.6e-05 25.0 0.2 4.3e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.9 CCF53118.1 - 1.1e-09 38.4 0.1 1.8e-05 24.7 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF53118.1 - 3.1e-07 30.6 0.1 0.002 18.2 0.0 3.4 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF53118.1 - 7.2e-07 29.5 0.3 4.6e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF53118.1 - 4.9e-06 25.6 0.0 8.9e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CCF53118.1 - 0.0037 15.9 1.2 0.56 8.7 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.1 CCF53118.1 - 0.0048 16.6 0.9 4.6 6.9 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCF53118.1 - 0.019 13.9 0.4 6.9 5.4 0.1 2.9 2 1 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.19 CCF53118.1 - 0.056 12.3 1.2 4.6 6.0 0.0 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase Arrestin_C PF02752.17 CCF53119.1 - 7e-19 68.2 0.0 2.4e-18 66.5 0.0 2.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCF53119.1 - 1.8e-09 37.6 0.4 1.3e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Sgf11 PF08209.6 CCF53120.1 - 9e-15 53.6 0.5 1.7e-14 52.7 0.4 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) RNA_pol_3_Rpc31 PF11705.3 CCF53120.1 - 0.054 13.4 13.7 0.18 11.6 0.4 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CAF1-p150_C2 PF15539.1 CCF53120.1 - 0.67 9.0 8.3 0.26 10.3 3.4 2.0 1 1 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Prothymosin PF03247.9 CCF53120.1 - 1.2 9.2 26.9 0.85 9.8 4.7 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family zf-C2HC_2 PF13913.1 CCF53120.1 - 2.4 7.9 4.8 0.51 10.0 0.2 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Bd3614_N PF14442.1 CCF53120.1 - 2.4 8.1 10.7 3.4 7.6 2.4 2.6 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Cwf_Cwc_15 PF04889.7 CCF53120.1 - 3.1 7.4 18.3 1.2 8.8 2.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GFA PF04828.9 CCF53122.1 - 6.5e-21 74.0 0.2 8.3e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CCF53122.1 - 0.0033 17.1 2.3 0.063 13.1 0.0 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-NADH-PPase PF09297.6 CCF53122.1 - 0.054 13.0 0.6 0.054 13.0 0.4 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CCF53122.1 - 0.19 10.9 0.1 0.19 10.9 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-LITAF-like PF10601.4 CCF53122.1 - 0.35 10.7 3.6 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.1 CCF53122.1 - 1.6 8.3 6.9 1 8.9 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Cyanate_lyase PF02560.9 CCF53123.1 - 9.9e-33 111.5 0.1 1.4e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 CCF53123.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_31 PF13560.1 CCF53123.1 - 0.021 15.0 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain SNase PF00565.12 CCF53124.1 - 2.5e-40 137.0 0.2 8.1e-18 64.6 0.0 6.2 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CCF53124.1 - 4.1e-18 65.3 0.0 8.8e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 CCF53124.1 - 0.036 13.1 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zn_clus PF00172.13 CCF53125.1 - 4.4e-07 29.7 7.7 8.1e-07 28.8 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Menin PF05053.8 CCF53126.1 - 1.1 7.3 4.3 1.4 7.0 3.0 1.1 1 0 0 1 1 1 0 Menin Herpes_capsid PF06112.6 CCF53126.1 - 1.9 8.4 17.9 3.1 7.8 12.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DNA_pol_viral_N PF00242.12 CCF53126.1 - 2.2 7.2 7.3 2.8 6.8 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NAD_binding_11 PF14833.1 CCF53127.1 - 1e-16 61.0 0.2 1.8e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Methyltransf_26 PF13659.1 CCF53129.1 - 3.5e-12 46.3 0.0 6.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF53129.1 - 9.7e-07 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CCF53129.1 - 5.4e-06 26.0 0.0 7.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF53129.1 - 0.0013 19.0 0.0 0.0049 17.2 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF53129.1 - 0.011 16.2 0.0 0.032 14.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CCF53129.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53129.1 - 0.054 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 CCF53129.1 - 0.066 14.0 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CCF53129.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 CCF53129.1 - 0.17 10.9 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 CCF53130.1 - 2e-65 221.1 0.0 7.9e-65 219.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SCP2 PF02036.12 CCF53131.1 - 2.3e-07 31.0 0.1 3e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Acyl_transf_1 PF00698.16 CCF53132.1 - 1.8e-15 57.0 1.8 2e-12 47.0 0.3 2.5 2 0 0 2 2 2 2 Acyl transferase domain MFS_1 PF07690.11 CCF53133.1 - 3e-34 118.2 61.0 1.1e-30 106.5 35.4 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF53133.1 - 1.5e-06 27.1 9.3 1.5e-06 27.1 6.5 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter YlaH PF14036.1 CCF53133.1 - 2.9 8.0 10.1 0.11 12.5 2.0 2.5 2 0 0 2 2 2 0 YlaH-like protein ADH_N PF08240.7 CCF53134.1 - 2.1e-28 98.2 0.5 3.5e-28 97.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF53134.1 - 3.4e-26 91.3 0.4 5.2e-26 90.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF53134.1 - 2.2e-07 31.8 0.5 6e-07 30.4 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2890 PF11081.3 CCF53135.1 - 9.7 6.2 7.3 1.1e+02 2.7 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Thiolase_N PF00108.18 CCF53136.1 - 1.2e-08 34.2 0.9 1.1e-07 31.0 0.1 2.2 1 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF53136.1 - 1.8e-08 33.8 0.3 1.3e-07 31.1 0.1 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCF53136.1 - 6.6e-05 22.5 3.0 0.00016 21.2 2.1 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCF53136.1 - 0.00039 20.0 1.8 0.0041 16.7 0.3 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.6 CCF53136.1 - 0.0093 14.4 0.3 0.048 12.0 0.2 2.0 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.17 CCF53136.1 - 0.033 14.0 0.6 0.39 10.5 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain MFS_1 PF07690.11 CCF53138.1 - 2.7e-41 141.4 34.7 2.7e-41 141.4 24.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCF53138.1 - 2.7e-12 45.7 1.3 4.1e-12 45.0 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCF53138.1 - 5.2e-11 41.7 26.0 5.7e-10 38.3 18.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter F-box-like PF12937.2 CCF53139.1 - 4.1e-07 29.6 0.3 4.1e-07 29.6 0.2 2.8 3 0 0 3 3 3 1 F-box-like LRR_7 PF13504.1 CCF53139.1 - 0.88 10.0 5.1 49 4.7 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat Abhydrolase_4 PF08386.5 CCF53140.1 - 1.3e-19 69.9 0.0 2.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 CCF53140.1 - 8.4e-13 48.4 0.0 5.2e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF53140.1 - 2.7e-06 27.4 0.0 2.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family NMO PF03060.10 CCF53141.1 - 7.7e-56 189.6 1.5 3.1e-55 187.6 1.0 1.7 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCF53141.1 - 3.1e-09 36.2 1.3 0.00055 18.9 1.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 CCF53141.1 - 0.00038 19.4 0.5 0.00038 19.4 0.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCF53141.1 - 0.0081 15.4 0.1 0.015 14.5 0.1 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 CCF53141.1 - 0.015 14.4 0.2 0.03 13.4 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI FBPase_glpX PF03320.8 CCF53141.1 - 0.059 11.9 1.6 0.1 11.2 0.9 1.5 1 1 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded DUF4367 PF14285.1 CCF53141.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) M20_dimer PF07687.9 CCF53142.1 - 3.6e-10 39.5 0.2 9.4e-10 38.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 CCF53142.1 - 5.3e-09 35.8 0.2 7.9e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MatE PF01554.13 CCF53143.1 - 4.5e-52 175.9 27.6 1e-30 106.5 7.5 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CCF53143.1 - 7.2e-07 29.1 10.3 7.2e-07 29.1 7.1 4.0 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain RVT_2 PF07727.9 CCF53145.1 - 1.9e-36 125.3 0.0 2.9e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF53145.1 - 4.2e-09 36.5 0.3 3e-07 30.5 0.2 2.4 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCF53145.1 - 0.099 12.1 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain GST_C_3 PF14497.1 CCF53146.1 - 0.0074 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sulfate_tra_GLY PF13792.1 CCF53146.1 - 0.059 13.0 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif Pterin_4a PF01329.14 CCF53147.1 - 3.1e-26 90.9 0.6 4.2e-26 90.5 0.4 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase DUF4042 PF13251.1 CCF53148.1 - 4.2e-17 62.1 12.1 4.6e-12 45.7 5.3 6.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.1 CCF53148.1 - 1e-06 28.8 18.3 0.0004 20.6 0.3 6.2 5 2 0 5 5 5 2 HEAT repeats HEAT PF02985.17 CCF53148.1 - 2e-05 24.2 20.6 0.23 11.6 0.1 7.9 8 0 0 8 8 8 3 HEAT repeat Tom37_C PF11801.3 CCF53148.1 - 0.0055 16.5 0.8 0.1 12.4 0.3 2.8 3 0 0 3 3 3 1 Tom37 C-terminal domain Arm PF00514.18 CCF53148.1 - 0.085 12.7 3.4 0.79 9.6 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Tic22 PF04278.7 CCF53148.1 - 0.13 11.4 0.7 0.32 10.2 0.5 1.6 1 0 0 1 1 1 0 Tic22-like family HEAT_EZ PF13513.1 CCF53148.1 - 1.3 9.5 25.4 5.5 7.6 0.1 7.4 8 0 0 8 8 8 0 HEAT-like repeat GFO_IDH_MocA PF01408.17 CCF53150.1 - 2.8e-23 82.7 0.1 4.4e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 CCF53150.1 - 0.0025 18.0 0.0 0.0077 16.5 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CRCB PF02537.10 CCF53151.1 - 9.5e-31 106.1 16.4 3.2e-18 65.7 3.6 2.6 2 1 0 2 2 2 2 CrcB-like protein Acetyltransf_1 PF00583.19 CCF53152.1 - 0.00023 21.1 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SNF2_N PF00176.18 CCF53153.1 - 4.5e-45 153.7 0.2 1.2e-44 152.3 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 CCF53153.1 - 7.5e-06 25.5 10.5 1.7e-05 24.4 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF53153.1 - 2.7e-05 24.0 13.7 5.5e-05 23.0 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF53153.1 - 4e-05 23.1 13.5 8.4e-05 22.1 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CCF53153.1 - 6.4e-05 22.7 0.0 0.00022 21.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCF53153.1 - 0.0003 20.4 12.7 0.0003 20.4 8.8 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCF53153.1 - 0.00061 19.5 12.6 0.0013 18.5 8.8 1.6 1 0 0 1 1 1 1 Ring finger domain DUF668 PF05003.7 CCF53153.1 - 0.013 15.6 1.0 0.19 11.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF668) zf-UDP PF14569.1 CCF53153.1 - 0.22 11.2 4.5 0.61 9.8 3.1 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF4501 PF14946.1 CCF53153.1 - 0.23 10.9 4.1 0.45 9.9 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Prok-RING_4 PF14447.1 CCF53153.1 - 0.57 9.7 5.7 2 8.0 3.9 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 CCF53153.1 - 0.69 9.8 10.8 1.5 8.7 7.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING BLOC1_2 PF10046.4 CCF53155.1 - 0.013 15.6 0.7 0.025 14.7 0.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DAHP_synth_2 PF01474.11 CCF53157.1 - 1.5e-158 527.7 0.0 2e-113 379.0 0.0 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family MFS_1 PF07690.11 CCF53158.1 - 1.1e-27 96.7 22.9 1.1e-27 96.7 15.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 CCF53158.1 - 0.00018 21.0 1.2 0.0008 18.9 0.1 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 CCF53158.1 - 0.13 11.6 11.2 3.3 7.0 2.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Ham1p_like PF01725.11 CCF53159.1 - 5.2e-52 175.9 0.0 5.8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Trypsin_2 PF13365.1 CCF53160.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain DUF2357 PF09823.4 CCF53161.1 - 2.5 7.1 5.6 17 4.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2357) DUF3074 PF11274.3 CCF53162.1 - 5.3e-41 140.2 0.1 1.1e-40 139.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) SinI PF08671.5 CCF53162.1 - 0.022 14.2 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Anti-repressor SinI PGG PF13962.1 CCF53163.1 - 0.02 14.5 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function HMGL-like PF00682.14 CCF53164.1 - 8.4e-45 153.2 0.0 1.4e-44 152.5 0.0 1.3 1 1 0 1 1 1 1 HMGL-like DUF1117 PF06547.7 CCF53165.1 - 0.053 13.6 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) rve PF00665.21 CCF53166.1 - 1e-14 54.6 0.2 1.8e-14 53.8 0.2 1.5 1 0 0 1 1 1 1 Integrase core domain RRF_GI PF12614.3 CCF53167.1 - 0.043 13.6 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Abhydrolase_5 PF12695.2 CCF53168.1 - 1.1e-20 73.8 0.0 1.5e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF53168.1 - 3.8e-16 59.6 0.1 2.6e-15 56.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCF53168.1 - 2.6e-09 36.9 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CCF53168.1 - 1e-08 35.0 0.2 2.1e-06 27.4 0.0 2.6 2 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CCF53168.1 - 3.6e-05 23.2 0.0 0.006 16.0 0.0 3.3 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CCF53168.1 - 0.00024 20.4 0.2 0.0041 16.3 0.1 2.6 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF818 PF05677.7 CCF53168.1 - 0.0013 17.5 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 CCF53168.1 - 0.025 14.2 0.0 0.16 11.6 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CCF53168.1 - 0.077 12.2 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CCF53168.1 - 0.1 12.4 0.2 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Esterase PF00756.15 CCF53168.1 - 0.11 11.8 0.2 1 8.7 0.2 2.1 1 1 0 1 1 1 0 Putative esterase LRR_4 PF12799.2 CCF53169.1 - 0.0004 19.9 1.1 0.84 9.3 0.0 4.5 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCF53169.1 - 0.0029 17.4 3.2 2.8 8.3 0.0 5.4 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.1 CCF53169.1 - 0.0047 16.8 10.8 1.2 9.3 0.0 5.9 8 0 0 8 8 8 2 Leucine Rich repeat F-box-like PF12937.2 CCF53169.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_7 PF13504.1 CCF53169.1 - 0.074 13.2 11.0 2.7 8.5 0.1 6.2 7 0 0 7 7 7 0 Leucine rich repeat Syja_N PF02383.13 CCF53170.1 - 5.4e-92 307.9 0.0 7.5e-92 307.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 CCF53171.1 - 3.1e-29 100.6 0.0 5e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase DUF667 PF05018.8 CCF53172.1 - 2.6e-14 52.8 0.0 7.4e-10 38.3 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF667) Cyt-b5 PF00173.23 CCF53173.1 - 2.1e-09 37.0 0.0 3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRK PF00485.13 CCF53174.1 - 3.7e-52 176.7 0.0 5.8e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CCF53174.1 - 8.7e-45 152.4 0.1 1.4e-42 145.2 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 CCF53174.1 - 2.7e-07 30.9 0.0 4.6e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF53174.1 - 1.7e-05 25.6 0.0 3.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 CCF53174.1 - 0.00011 21.6 0.0 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.1 CCF53174.1 - 0.00052 19.8 0.0 0.0019 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 CCF53174.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 CCF53174.1 - 0.095 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CCF53174.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.1 CCF53175.1 - 0.0069 16.1 0.0 0.03 14.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 CCF53175.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_31 PF13847.1 CCF53175.1 - 0.023 14.2 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain AAA_17 PF13207.1 CCF53176.1 - 3.1e-05 24.7 0.2 0.0002 22.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF53176.1 - 0.00017 21.9 0.0 0.00089 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF53176.1 - 0.001 18.9 1.0 0.16 11.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCF53176.1 - 0.0032 16.3 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein NB-ARC PF00931.17 CCF53176.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 CCF53176.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.5 CCF53176.1 - 0.016 14.4 0.1 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 CCF53176.1 - 0.02 14.6 0.1 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain PRK PF00485.13 CCF53176.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 CCF53176.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CCF53176.1 - 0.044 12.7 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCF53176.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CCF53176.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RVT_2 PF07727.9 CCF53178.1 - 2.6e-37 128.1 0.0 3.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CCF53178.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase H Lipoprotein_8 PF02030.10 CCF53178.1 - 0.15 10.5 0.4 0.22 9.9 0.2 1.2 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) DUF3292 PF11696.3 CCF53179.1 - 1.3e-05 23.3 0.2 1.3e-05 23.3 0.1 3.8 5 0 0 5 5 5 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 CCF53179.1 - 0.0008 18.9 4.4 0.22 11.0 0.9 2.3 1 1 1 2 2 2 2 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 CCF53179.1 - 0.11 12.0 7.4 2 7.9 0.5 2.3 2 0 0 2 2 2 0 Reticulon Sigma_reg_N PF13800.1 CCF53180.1 - 0.03 14.3 0.2 0.048 13.6 0.1 1.5 1 1 0 1 1 1 0 Sigma factor regulator N-terminal Polysacc_deac_1 PF01522.16 CCF53182.1 - 4e-30 103.9 0.0 5.9e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2962 PF11176.3 CCF53184.1 - 1.9e-40 137.9 0.2 3.1e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) HTH_32 PF13565.1 CCF53184.1 - 0.11 13.3 0.5 0.2 12.5 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain RTA1 PF04479.8 CCF53185.1 - 4.9e-26 91.6 7.2 2.4e-21 76.2 1.0 2.2 2 0 0 2 2 2 2 RTA1 like protein DUF350 PF03994.9 CCF53185.1 - 1.5 8.6 7.1 0.23 11.1 0.6 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Zn_clus PF00172.13 CCF53186.1 - 0.012 15.5 7.5 0.012 15.5 5.2 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 CCF53187.1 - 2.5e-42 145.0 0.1 4.1e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF53187.1 - 4.3e-20 72.4 0.2 4.3e-20 72.4 0.1 2.9 3 1 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.19 CCF53187.1 - 2.6e-07 29.8 4.2 0.0021 16.9 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CCF53187.1 - 2.9e-05 24.0 0.4 0.001 18.9 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCF53187.1 - 4.7e-05 22.6 0.3 7.9e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCF53187.1 - 5e-05 22.3 4.0 0.095 11.5 1.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF53187.1 - 0.0034 17.3 1.4 0.0097 15.9 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 CCF53187.1 - 0.006 16.4 1.7 0.039 13.7 0.8 2.4 2 0 0 2 2 2 1 ThiF family GIDA PF01134.17 CCF53187.1 - 0.031 13.1 0.1 0.06 12.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CCF53187.1 - 0.046 12.8 0.4 0.088 11.8 0.3 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 CCF53187.1 - 0.067 11.6 0.8 0.34 9.3 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Amidohydro_2 PF04909.9 CCF53189.1 - 1.8e-41 142.5 0.9 2.3e-41 142.1 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase Pan_kinase PF03309.9 CCF53189.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Type III pantothenate kinase Acetyltransf_1 PF00583.19 CCF53190.1 - 4.8e-10 39.3 0.0 6.5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF53190.1 - 1.6e-08 34.5 0.0 2.1e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF53190.1 - 0.00031 20.7 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF53190.1 - 0.00041 20.4 0.0 0.00049 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCF53190.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.22 CCF53191.1 - 8.1e-50 168.6 0.7 1.9e-26 93.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCF53191.1 - 4.7e-30 104.9 23.9 1.2e-20 74.1 6.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CCF53191.1 - 1.5e-11 43.9 1.5 7.5e-05 22.0 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF53191.1 - 8.8e-09 35.7 0.0 0.24 11.3 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 CCF53191.1 - 3.5e-07 29.6 0.3 0.037 13.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF53191.1 - 7.9e-06 26.0 1.0 0.046 13.8 0.3 3.3 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCF53191.1 - 2.6e-05 23.4 0.0 0.27 10.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCF53191.1 - 2.7e-05 23.6 0.5 0.13 11.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CCF53191.1 - 4.4e-05 23.0 0.0 0.19 11.1 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 CCF53191.1 - 0.00024 20.6 0.9 0.71 9.2 0.0 3.0 3 1 0 3 3 2 2 AAA-like domain Miro PF08477.8 CCF53191.1 - 0.001 19.5 0.1 0.4 11.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 CCF53191.1 - 0.0015 18.8 0.1 0.096 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCF53191.1 - 0.0052 16.7 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 CCF53191.1 - 0.009 16.2 2.2 2 8.6 0.6 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CCF53191.1 - 0.014 15.2 0.9 1.1 9.2 0.0 3.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCF53191.1 - 0.021 14.7 0.5 10 5.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 CCF53191.1 - 0.03 12.9 6.6 0.03 12.8 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 CCF53191.1 - 0.066 13.3 0.1 45 4.2 0.0 3.4 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.17 CCF53191.1 - 0.072 11.9 0.5 17 4.1 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain Dynamin_N PF00350.18 CCF53191.1 - 0.091 12.5 0.3 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 CCF53191.1 - 0.13 11.9 0.7 18 4.9 0.2 3.0 2 1 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 CCF53191.1 - 0.14 11.8 0.2 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MARVEL PF01284.18 CCF53192.1 - 6.5e-09 35.7 4.1 1.1e-08 34.9 2.8 1.4 1 0 0 1 1 1 1 Membrane-associating domain SieB PF14163.1 CCF53192.1 - 0.46 10.0 1.8 0.79 9.2 1.2 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1772 PF08592.6 CCF53192.1 - 0.84 9.3 6.1 0.87 9.3 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Cmc1 PF08583.5 CCF53193.1 - 5.9e-13 48.3 1.2 7.2e-13 48.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 CCF53193.1 - 4.9e-05 22.6 0.6 6.7e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3596 PF12167.3 CCF53193.1 - 0.081 12.4 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) Pet191_N PF10203.4 CCF53193.1 - 0.096 12.7 0.4 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PCI_Csn8 PF10075.4 CCF53193.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.5 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF2237 PF09996.4 CCF53194.1 - 2.4e-19 68.9 0.1 8.1e-19 67.2 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) LRR_8 PF13855.1 CCF53195.1 - 7.6e-17 60.8 30.2 2e-10 40.2 4.5 4.0 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 CCF53195.1 - 1.6e-14 53.1 24.1 1.8e-07 30.6 1.8 5.4 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCF53195.1 - 3.2e-06 26.4 26.5 1.6 9.0 0.3 7.8 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.1 CCF53195.1 - 3.2e-06 26.8 0.7 0.0082 15.7 0.1 3.0 3 0 0 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 CCF53195.1 - 0.0027 17.6 28.7 6.1 7.5 0.3 8.7 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 CCF53195.1 - 4.5 7.6 21.4 9.8 6.6 0.8 6.6 6 1 0 6 6 6 0 Leucine Rich repeat AA_permease_2 PF13520.1 CCF53196.1 - 1.2e-61 208.5 38.3 1.5e-61 208.2 26.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCF53196.1 - 1.3e-26 92.9 33.8 1.7e-26 92.6 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease Ndc1_Nup PF09531.5 CCF53196.1 - 4.2 5.6 7.7 9.9 4.4 1.9 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup FDF PF09532.5 CCF53197.1 - 0.00018 21.9 0.0 0.00077 19.9 0.0 2.1 1 0 0 1 1 1 1 FDF domain LBR_tudor PF09465.5 CCF53197.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Orbi_VP2 PF00898.12 CCF53197.1 - 0.27 8.7 0.0 0.44 8.0 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 NUDIX PF00293.23 CCF53198.1 - 3.4e-13 49.4 0.0 9.7e-13 47.9 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DnaJ PF00226.26 CCF53199.1 - 6e-25 86.7 1.0 1e-24 86.0 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCF53199.1 - 2.5e-21 75.3 0.9 6.5e-20 70.8 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCF53199.1 - 4.8e-14 52.1 19.0 8.1e-14 51.4 13.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 CCF53199.1 - 0.028 14.7 11.5 0.053 13.8 7.4 1.9 1 1 1 2 2 2 0 Cytochrome c3 Stc1 PF12898.2 CCF53199.1 - 0.076 13.0 12.1 0.64 10.1 2.7 2.3 1 1 1 2 2 2 0 Stc1 domain HypA PF01155.14 CCF53199.1 - 3.2 7.4 13.3 0.87 9.2 2.8 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 CCF53199.1 - 5.4 6.7 13.8 21 4.8 9.5 2.0 1 1 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 CCF53199.1 - 7.8 6.8 8.0 2.1 8.6 2.3 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar DcpS PF05652.7 CCF53200.1 - 4.7e-28 97.7 0.0 8.4e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCF53200.1 - 9.1e-28 96.8 1.3 4.3e-27 94.6 0.6 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Nop16 PF09420.5 CCF53201.1 - 0.0045 17.1 1.3 0.0057 16.7 0.9 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DHBP_synthase PF00926.14 CCF53201.1 - 0.048 12.8 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIA PF03153.8 CCF53201.1 - 0.3 10.9 12.2 0.35 10.7 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_85 PF03644.8 CCF53202.1 - 3e-94 315.6 0.0 4.2e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 DUF2470 PF10615.4 CCF53203.1 - 2.5e-24 85.3 0.0 4.9e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 CCF53203.1 - 1.9e-05 24.5 0.2 3.4e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) DctQ PF04290.7 CCF53203.1 - 0.088 12.5 1.9 0.25 11.1 0.6 2.0 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component FAA_hydrolase PF01557.13 CCF53204.1 - 4.1e-53 180.0 0.0 5.4e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CoA_binding_2 PF13380.1 CCF53205.1 - 5.4e-25 87.8 0.0 6.3e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Herpes_gp2 PF05955.6 CCF53205.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Aldose_epim PF01263.15 CCF53206.1 - 6.3e-57 192.9 0.6 7.5e-57 192.7 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_92 PF07971.7 CCF53208.1 - 1.9e-152 508.4 0.1 2.6e-152 508.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1275 PF06912.6 CCF53209.1 - 8.5e-15 54.5 17.1 2.2e-14 53.1 11.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) DUF46 PF01864.12 CCF53209.1 - 0.0008 19.3 0.2 0.0019 18.0 0.1 1.6 1 1 0 1 1 1 1 Putative integral membrane protein DUF46 GFO_IDH_MocA PF01408.17 CCF53210.1 - 1e-14 55.0 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCF53210.1 - 7.5e-13 48.2 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain SNase PF00565.12 CCF53211.1 - 1.1e-19 70.6 0.8 2.7e-08 34.0 0.4 3.2 2 1 0 2 2 2 2 Staphylococcal nuclease homologue PQ-loop PF04193.9 CCF53212.1 - 4.7e-24 83.7 7.8 8.5e-13 47.6 0.5 2.7 3 0 0 3 3 3 2 PQ loop repeat Ceramidase PF05875.7 CCF53212.1 - 0.13 11.3 5.6 0.033 13.3 1.5 1.6 1 1 1 2 2 2 0 Ceramidase SelP_N PF04592.9 CCF53213.1 - 2.1 7.6 8.7 3.8 6.8 6.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FLO_LFY PF01698.11 CCF53215.1 - 5.5 5.7 5.9 7.8 5.2 4.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Transthyretin PF00576.16 CCF53216.1 - 2.6e-34 117.4 0.0 3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 CCF53216.1 - 0.0074 16.8 0.0 0.0096 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain Mito_carr PF00153.22 CCF53217.1 - 9.7e-51 169.4 3.4 7.2e-17 60.8 0.0 3.5 2 1 2 4 4 4 3 Mitochondrial carrier protein IU_nuc_hydro PF01156.14 CCF53218.1 - 4.2e-60 203.6 0.1 5.4e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase GSHPx PF00255.14 CCF53219.1 - 5.1e-40 135.2 0.8 6.4e-40 134.8 0.5 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCF53219.1 - 1.9e-07 30.8 0.2 2e-06 27.5 0.1 2.0 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCF53219.1 - 8.1e-07 28.6 0.0 1.5e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 CCF53219.1 - 0.0067 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Thioredoxin_2 PF13098.1 CCF53219.1 - 0.067 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain S-methyl_trans PF02574.11 CCF53222.1 - 9.4e-22 77.6 3.8 4.8e-17 62.2 0.0 4.4 2 2 0 2 2 2 2 Homocysteine S-methyltransferase Polysacc_deac_1 PF01522.16 CCF53223.1 - 8.8e-26 89.9 0.0 1.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Erg28 PF03694.8 CCF53224.1 - 1.6e-34 118.2 0.9 2e-34 117.9 0.7 1.1 1 0 0 1 1 1 1 Erg28 like protein DNA_ligase_OB_2 PF14743.1 CCF53225.1 - 8.7e-23 79.7 0.0 2e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 CCF53225.1 - 2.3e-11 43.4 0.0 7.9e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain UPF0547 PF10571.4 CCF53225.1 - 0.11 12.1 1.4 0.37 10.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Abhydrolase_3 PF07859.8 CCF53226.1 - 9.9e-38 129.8 0.2 1e-30 106.9 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CCF53226.1 - 1.4e-09 37.0 0.0 3e-08 32.7 0.3 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CCF53226.1 - 5.1e-05 23.0 0.1 0.00019 21.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 CCF53226.1 - 0.016 13.7 0.1 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.23 CCF53226.1 - 0.025 13.3 0.1 1.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 CCF53226.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF966 PF06136.8 CCF53226.1 - 6.5 6.0 15.8 0.36 10.1 2.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF966) Aldo_ket_red PF00248.16 CCF53228.1 - 4e-63 212.8 0.0 5e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family A_deaminase PF00962.17 CCF53229.1 - 8.7e-48 162.9 0.0 1.2e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mg_trans_NIPA PF05653.9 CCF53231.1 - 1.6e-91 306.4 23.6 2.4e-91 305.8 16.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CCF53231.1 - 2.5e-06 27.6 5.2 2.5e-06 27.6 3.6 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCF53231.1 - 3.8e-06 26.9 8.2 3.8e-06 26.9 5.7 3.4 2 1 1 3 3 3 1 EamA-like transporter family WSN PF02206.13 CCF53231.1 - 0.0048 16.6 0.4 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function PGPGW PF09656.5 CCF53231.1 - 7.5 5.9 8.0 37 3.7 1.9 3.3 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Mito_carr PF00153.22 CCF53232.1 - 1.7e-52 175.1 3.8 5.5e-19 67.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein START PF01852.14 CCF53233.1 - 4.2e-11 42.5 0.2 7.4e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 START domain TMEM52 PF14979.1 CCF53233.1 - 0.1 12.4 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 MoaE PF02391.12 CCF53234.1 - 6.4e-27 93.6 0.0 1.2e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 MoaE protein Ribonuclease PF00545.15 CCF53235.1 - 2.2e-18 66.0 1.8 2.8e-18 65.7 1.3 1.1 1 0 0 1 1 1 1 ribonuclease Thioredoxin PF00085.15 CCF53236.1 - 1.7e-60 201.1 0.1 1.9e-30 104.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CCF53236.1 - 1.4e-24 86.5 1.3 1.4e-24 86.5 0.9 2.5 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CCF53236.1 - 5.3e-13 49.1 7.9 4.2e-07 30.1 0.1 3.6 3 3 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF53236.1 - 1e-11 44.7 1.3 0.0011 18.9 0.0 4.4 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CCF53236.1 - 1.7e-09 37.5 1.4 1.3e-05 25.1 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CCF53236.1 - 3.6e-08 33.1 1.1 0.01 15.4 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CCF53236.1 - 2.7e-05 23.7 0.0 0.19 11.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CCF53236.1 - 5.9e-05 22.9 2.8 0.0056 16.5 0.0 3.4 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 CCF53236.1 - 8e-05 22.2 2.5 0.17 11.4 0.0 2.6 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 CCF53236.1 - 0.0006 19.5 0.0 1.2 8.9 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain HyaE PF07449.6 CCF53236.1 - 0.0025 17.6 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Transcrip_act PF04949.8 CCF53236.1 - 0.0086 15.7 6.6 0.014 14.9 4.6 1.3 1 0 0 1 1 1 1 Transcriptional activator Propeptide_C1 PF08127.8 CCF53236.1 - 0.02 14.5 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C1 propeptide DAZAP2 PF11029.3 CCF53236.1 - 0.07 13.6 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Thioredoxin_4 PF13462.1 CCF53236.1 - 0.15 12.0 11.6 1.9 8.4 0.0 3.8 3 3 0 3 3 3 0 Thioredoxin NCA2 PF08637.5 CCF53237.1 - 1.6e-93 312.8 0.1 6.2e-93 310.8 0.0 2.0 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Aminotran_1_2 PF00155.16 CCF53239.1 - 1e-17 64.1 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCF53239.1 - 3.6e-07 29.1 0.0 9.5e-07 27.7 0.0 1.5 1 1 1 2 2 2 1 Alanine-glyoxylate amino-transferase Frag1 PF10277.4 CCF53240.1 - 9.4e-36 123.3 19.5 1.1e-35 123.0 13.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DAP PF15228.1 CCF53240.1 - 0.088 13.5 0.2 0.16 12.6 0.1 1.4 1 0 0 1 1 1 0 Death-associated protein DUF4131 PF13567.1 CCF53240.1 - 1.4 8.3 15.4 0.64 9.4 1.3 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Cation_ATPase_C PF00689.16 CCF53240.1 - 1.8 8.0 15.1 2.2 7.7 5.6 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF4227 PF14004.1 CCF53240.1 - 7 6.5 6.0 15 5.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) XPG_I_2 PF12813.2 CCF53241.1 - 1.8e-12 47.2 0.0 2.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 CCF53241.1 - 9.3e-05 22.6 0.0 0.0062 16.7 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain Pox_RNA_Pol_19 PF05320.7 CCF53241.1 - 0.14 11.9 5.5 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nucleoplasmin PF03066.10 CCF53241.1 - 0.25 10.8 7.1 0.49 9.8 4.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 CCF53241.1 - 1.7 7.7 6.0 3.1 6.8 4.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 CCF53241.1 - 2.3 6.0 6.1 3 5.6 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCF53241.1 - 3.2 6.1 5.4 5.2 5.4 3.8 1.3 1 0 0 1 1 1 0 Daxx Family Lactamase_B PF00753.22 CCF53242.1 - 7.4e-20 71.4 0.5 1.3e-19 70.6 0.4 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCF53242.1 - 1.4e-05 24.6 0.1 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Evr1_Alr PF04777.8 CCF53243.1 - 2.2e-29 101.1 0.2 4.2e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Glyco_hydro_cc PF11790.3 CCF53244.1 - 2.1e-45 155.0 0.0 3.3e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1510 PF07423.6 CCF53244.1 - 0.36 10.1 5.3 0.81 9.0 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 CCF53244.1 - 0.38 9.7 20.2 0.51 9.3 14.0 1.1 1 0 0 1 1 1 0 BUD22 MIP-T3 PF10243.4 CCF53244.1 - 5.5 5.3 10.9 7.1 4.9 7.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CCF53244.1 - 8.8 4.4 45.7 13 3.9 31.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Aldose_epim PF01263.15 CCF53245.1 - 1.7e-15 56.9 0.0 3.5e-13 49.3 0.0 3.0 1 1 0 1 1 1 1 Aldose 1-epimerase CIA30 PF08547.7 CCF53246.1 - 3.7e-22 78.8 0.0 2.6e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) His_Phos_2 PF00328.17 CCF53247.1 - 6.8e-15 55.2 0.0 1.7e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) WzyE PF06899.6 CCF53247.1 - 0.099 11.3 0.1 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 WzyE protein Acatn PF13000.2 CCF53248.1 - 4.5e-136 454.5 34.2 4.3e-65 220.2 11.6 4.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF2423 PF10338.4 CCF53248.1 - 0.17 11.8 3.6 0.28 11.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) Peptidase_M48 PF01435.13 CCF53249.1 - 3e-32 112.0 0.0 4.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 HTH_1 PF00126.22 CCF53249.1 - 0.042 13.5 0.2 2.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family adh_short PF00106.20 CCF53250.1 - 5.7e-16 58.8 0.5 5.9e-13 49.0 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCF53250.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 KR domain FtsJ PF01728.14 CCF53251.1 - 1.2e-59 201.3 0.0 1.6e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCF53251.1 - 0.088 13.3 0.0 0.25 11.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain rRNA_processing PF08524.6 CCF53252.1 - 2.7e-09 36.9 11.8 5.9e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 rRNA processing Methyltransf_PK PF05891.7 CCF53253.1 - 7.8e-60 201.8 0.0 2.1e-34 118.7 0.0 3.0 3 0 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CCF53253.1 - 8e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53253.1 - 4.9e-06 26.9 0.0 0.0037 17.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CCF53253.1 - 5.5e-05 23.4 0.0 0.0021 18.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF53253.1 - 7e-05 23.2 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF53253.1 - 0.00038 20.9 0.0 0.00066 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCF53253.1 - 0.0065 15.6 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase DUF1399 PF07173.7 CCF53254.1 - 2.1e-09 37.7 2.2 1.6e-06 28.4 0.4 3.3 2 1 2 4 4 4 2 Protein of unknown function (DUF1399) Zn_Tnp_IS1 PF03811.8 CCF53254.1 - 0.044 13.2 2.4 0.07 12.6 0.1 2.5 2 0 0 2 2 2 0 InsA N-terminal domain PSCyt2 PF07583.6 CCF53254.1 - 0.081 12.4 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) DUF4551 PF15087.1 CCF53254.1 - 0.16 10.2 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) adh_short PF00106.20 CCF53256.1 - 1e-31 110.1 1.6 1.3e-31 109.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF53256.1 - 1.6e-26 93.5 0.7 4.9e-26 91.9 0.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF53256.1 - 1.6e-14 53.9 0.4 2.3e-14 53.4 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 CCF53256.1 - 0.0028 17.3 0.6 0.0043 16.7 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CCF53256.1 - 0.024 14.0 0.2 0.032 13.6 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 CCF53256.1 - 0.036 14.1 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CCF53256.1 - 0.065 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_M24 PF00557.19 CCF53257.1 - 1.5e-40 138.9 0.0 1.9e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Abhydrolase_6 PF12697.2 CCF53258.1 - 2e-27 96.5 0.0 2.5e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF53258.1 - 2.3e-15 56.6 0.0 3.9e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF53258.1 - 7.3e-11 42.0 0.1 1.2e-09 38.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CCF53258.1 - 2.5e-10 40.3 0.0 6.3e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 CCF53258.1 - 3e-07 30.8 0.0 5.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CCF53258.1 - 0.00029 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 CCF53258.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 CCF53258.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 CCF53258.1 - 0.055 12.7 0.0 0.17 11.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2048 PF09752.4 CCF53258.1 - 0.085 11.7 0.1 10 4.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) LCAT PF02450.10 CCF53258.1 - 0.099 11.5 0.1 0.24 10.3 0.1 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase MobB PF03205.9 CCF53260.1 - 4.4e-05 23.2 0.1 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCF53260.1 - 0.00011 22.9 0.0 0.00025 21.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCF53260.1 - 0.00024 21.1 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CCF53260.1 - 0.00043 20.1 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCF53260.1 - 0.00053 19.4 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ArgK PF03308.11 CCF53260.1 - 0.0011 17.7 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 CCF53260.1 - 0.0022 17.1 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 CCF53260.1 - 0.0039 16.6 0.0 0.011 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CCF53260.1 - 0.007 15.9 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 CCF53260.1 - 0.0075 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CCF53260.1 - 0.0076 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF53260.1 - 0.0082 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCF53260.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.10 CCF53260.1 - 0.0092 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 NTPase AAA_10 PF12846.2 CCF53260.1 - 0.0095 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 CCF53260.1 - 0.01 15.5 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 CCF53260.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CCF53260.1 - 0.019 15.1 0.1 0.051 13.7 0.0 1.8 2 0 0 2 2 1 0 RNA helicase KTI12 PF08433.5 CCF53260.1 - 0.021 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LpxK PF02606.9 CCF53260.1 - 0.023 13.6 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase cobW PF02492.14 CCF53260.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 CCF53260.1 - 0.045 13.3 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.12 CCF53260.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase CbiA PF01656.18 CCF53260.1 - 0.077 12.3 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CCF53260.1 - 0.078 12.0 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA PF00004.24 CCF53260.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCF53260.1 - 0.094 12.6 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCF53260.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.6 CCF53260.1 - 0.12 12.2 0.1 0.38 10.6 0.0 1.8 1 1 1 2 2 2 0 Torsin AAA_11 PF13086.1 CCF53260.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCF53260.1 - 0.15 11.7 0.0 0.46 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF938 PF06080.7 CCF53261.1 - 3.1e-31 108.5 0.1 9.8e-31 106.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF938) CENP-B_dimeris PF09026.5 CCF53262.1 - 1.7 8.9 11.8 7.3 6.8 4.5 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain His_Phos_2 PF00328.17 CCF53264.1 - 4.7e-23 82.0 0.0 7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) She2p PF11435.3 CCF53264.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding protein She2p Fungal_trans PF04082.13 CCF53265.1 - 3.2e-23 81.9 1.5 3.9e-23 81.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53265.1 - 8.2e-08 32.0 8.9 1.4e-07 31.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EAF PF09816.4 CCF53266.1 - 1.3e-27 95.9 0.1 3.1e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Alpha-L-AF_C PF06964.7 CCF53267.1 - 4.5e-28 98.2 0.1 6.8e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 CCF53267.1 - 9.3e-06 25.6 0.0 3.1e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain AMP-binding PF00501.23 CCF53268.1 - 4.1e-29 101.2 0.1 1.1e-28 99.8 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCF53268.1 - 2.4e-27 95.4 0.0 5e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CCF53268.1 - 3.7e-06 26.5 0.0 8.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCF53268.1 - 5.7e-06 26.1 0.1 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCF53268.1 - 5.9e-06 26.2 0.1 1.8e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 CCF53268.1 - 0.0056 16.9 0.1 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 CCF53268.1 - 0.0071 15.0 0.0 0.052 12.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCF53268.1 - 0.017 15.1 0.2 0.49 10.3 0.1 2.4 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCF53268.1 - 0.021 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KxDL PF10241.4 CCF53268.1 - 0.074 12.9 0.2 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein HAD_2 PF13419.1 CCF53269.1 - 7.8e-11 42.5 0.0 1.6e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCF53269.1 - 9.4e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCF53269.1 - 0.00033 21.1 0.0 0.00053 20.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amastin PF07344.6 CCF53270.1 - 0.036 13.6 0.9 0.079 12.5 0.6 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein zf-DHHC PF01529.15 CCF53271.1 - 1.9e-52 177.1 0.0 5.4e-52 175.6 0.0 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Hemagglutinin PF00509.13 CCF53271.1 - 0.0028 15.8 0.0 0.0042 15.3 0.0 1.1 1 0 0 1 1 1 1 Haemagglutinin DZR PF12773.2 CCF53271.1 - 0.078 12.8 3.8 0.2 11.5 2.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon LIM PF00412.17 CCF53272.1 - 3e-21 75.2 16.2 3.7e-12 46.1 4.7 2.6 3 0 0 3 3 3 2 LIM domain zf-C3HC4_2 PF13923.1 CCF53272.1 - 1.1 9.2 6.7 0.52 10.3 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Cytochrom_c3_2 PF14537.1 CCF53272.1 - 3.6 7.9 10.0 1.7 9.0 3.2 2.4 2 0 0 2 2 2 0 Cytochrome c3 PMSR PF01625.16 CCF53273.1 - 1.2e-56 190.9 2.0 1.5e-56 190.5 1.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Exo70 PF03081.10 CCF53274.1 - 4.2e-83 279.1 0.0 6.7e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit SLT PF01464.15 CCF53275.1 - 2.1e-07 30.4 0.0 0.0036 16.7 0.0 2.7 2 0 0 2 2 2 2 Transglycosylase SLT domain Dicty_REP PF05086.7 CCF53275.1 - 0.31 8.7 0.6 0.41 8.3 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Thiolase_N PF00108.18 CCF53276.1 - 8.9e-73 244.5 0.1 1.3e-72 243.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF53276.1 - 4.3e-42 142.4 0.1 7.8e-42 141.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCF53276.1 - 0.005 16.3 0.6 0.013 15.0 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain zf-CCHC_3 PF13917.1 CCF53277.1 - 0.046 13.4 0.5 0.1 12.3 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 CCF53277.1 - 0.094 12.6 3.5 0.22 11.4 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Nucleos_tra2_C PF07662.8 CCF53278.1 - 1.9e-63 213.7 8.7 1.9e-63 213.7 6.0 2.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 CCF53278.1 - 6.9e-08 32.7 7.5 6.9e-08 32.7 5.2 3.3 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 CCF53278.1 - 1.8 8.5 23.4 0.035 14.0 8.8 3.4 2 1 1 3 3 3 0 Nucleoside recognition DPM2 PF07297.7 CCF53279.1 - 4.9e-20 71.5 0.5 6.2e-20 71.2 0.4 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CCF53279.1 - 1.6e-06 27.7 0.4 1.9e-06 27.5 0.3 1.1 1 0 0 1 1 1 1 PIG-P DUF1648 PF07853.6 CCF53279.1 - 0.098 12.1 0.8 0.62 9.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1648) Myc_N PF01056.13 CCF53280.1 - 0.026 13.7 0.7 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region SHD1 PF03983.7 CCF53280.1 - 0.15 11.7 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 SLA1 homology domain 1, SHD1 Peptidase_S24 PF00717.18 CCF53281.1 - 4.6e-06 26.1 0.1 2.9e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCF53281.1 - 0.0047 16.4 0.0 0.074 12.5 0.0 2.4 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 DUF3425 PF11905.3 CCF53282.1 - 1.2e-10 41.4 3.3 1.2e-10 41.4 2.3 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 CCF53282.1 - 2.2e-08 33.9 8.5 2.2e-08 33.9 5.9 2.5 2 1 1 3 3 3 1 bZIP transcription factor SprA-related PF12118.3 CCF53282.1 - 0.16 11.2 35.2 1 8.6 3.0 2.2 2 0 0 2 2 2 0 SprA-related family DUF4407 PF14362.1 CCF53282.1 - 2.5 6.9 24.9 0.05 12.5 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNase_H2-Ydr279 PF09468.5 CCF53282.1 - 2.7 7.0 9.2 0.047 12.8 0.3 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) VHS PF00790.14 CCF53283.1 - 9e-27 93.4 0.0 2.1e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CCF53283.1 - 2.5e-05 24.1 4.0 4.3e-05 23.4 1.7 2.1 2 0 0 2 2 2 1 GAT domain Tho2 PF11262.3 CCF53284.1 - 4.8 6.1 5.3 7.4 5.5 3.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Vfa1 PF08432.5 CCF53284.1 - 6.7 6.6 20.1 4.4 7.2 12.3 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Carn_acyltransf PF00755.15 CCF53285.1 - 5.4e-166 553.1 0.0 6.6e-166 552.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-CHY PF05495.7 CCF53287.1 - 6.9e-15 54.9 17.0 9.3e-15 54.5 11.8 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 CCF53287.1 - 0.0077 15.8 0.6 0.0077 15.8 0.4 2.3 2 0 0 2 2 1 1 Zinc finger found in FPG and IleRS Cys_rich_KTR PF14205.1 CCF53287.1 - 0.0079 15.6 6.0 0.21 11.0 1.7 2.3 1 1 1 2 2 2 2 Cysteine-rich KTR zinc_ribbon_2 PF13240.1 CCF53287.1 - 0.013 14.9 9.9 0.021 14.3 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CCF53287.1 - 0.087 12.6 10.0 0.78 9.5 4.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CCF53287.1 - 0.13 12.2 12.8 0.34 10.8 2.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 CCF53287.1 - 0.19 10.9 7.2 14 5.0 5.0 2.6 1 1 0 1 1 1 0 zinc-ribbon domain DRP PF06044.7 CCF53287.1 - 0.22 10.5 2.1 0.42 9.5 0.2 1.9 1 1 1 2 2 2 0 Dam-replacing family DZR PF12773.2 CCF53287.1 - 0.53 10.1 10.2 2.8 7.8 7.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 CCF53287.1 - 0.74 9.5 7.9 0.069 12.8 0.6 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF3797 PF12677.2 CCF53287.1 - 2 8.0 4.9 6.3 6.5 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Elf1 PF05129.8 CCF53287.1 - 2.4 7.9 9.9 45 3.8 6.9 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Evr1_Alr PF04777.8 CCF53287.1 - 2.5 8.0 10.0 55 3.7 6.9 2.7 1 1 0 1 1 1 0 Erv1 / Alr family TF_Zn_Ribbon PF08271.7 CCF53287.1 - 2.6 7.4 7.3 12 5.3 0.1 2.9 2 1 0 2 2 2 0 TFIIB zinc-binding C1_4 PF07975.7 CCF53287.1 - 4.3 7.4 12.3 0.59 10.1 2.3 2.4 1 1 2 3 3 3 0 TFIIH C1-like domain zf-RING_3 PF14369.1 CCF53287.1 - 5.4 7.1 11.9 0.84 9.6 2.2 2.8 2 1 1 3 3 3 0 zinc-finger Ofd1_CTDD PF10637.4 CCF53288.1 - 4.5e-96 321.0 0.0 4e-90 301.5 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCF53288.1 - 1.1e-17 64.3 0.1 2.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SCP2 PF02036.12 CCF53289.1 - 3.3e-17 62.6 0.0 4.9e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCF53289.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal GPI-anchored PF10342.4 CCF53290.1 - 2.5e-11 43.8 0.0 2.5e-11 43.8 0.0 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EHN PF06441.7 CCF53291.1 - 2.6e-31 107.8 0.1 4.7e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 CCF53291.1 - 2.6e-09 37.2 0.5 4.1e-09 36.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF53291.1 - 4.1e-07 29.7 0.1 7.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 CCF53291.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PhzC-PhzF PF02567.11 CCF53292.1 - 9.9e-50 169.3 0.0 1.2e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 CCF53292.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase PhoD PF09423.5 CCF53293.1 - 5.5e-137 457.0 7.8 6.9e-137 456.7 5.4 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 CCF53293.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Phytase-like PF13449.1 CCF53294.1 - 4.6e-19 68.8 0.2 1.6e-18 67.0 0.1 2.1 1 1 0 1 1 1 1 Esterase-like activity of phytase DUF2719 PF10891.3 CCF53294.1 - 0.085 12.5 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) ADH_N PF08240.7 CCF53295.1 - 3.2e-23 81.5 5.9 3.2e-23 81.5 4.1 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF53295.1 - 1e-16 60.6 0.2 5.2e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF53295.1 - 2.9e-05 24.9 0.0 6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCF53295.1 - 3.6e-05 22.9 0.0 0.00048 19.3 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 CCF53295.1 - 0.026 13.1 0.0 0.036 12.7 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase NADH_4Fe-4S PF10589.4 CCF53295.1 - 0.059 12.5 0.9 0.14 11.3 0.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region PTH2 PF01981.11 CCF53296.1 - 1.9e-45 153.2 0.5 2.4e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Sua5_yciO_yrdC PF01300.13 CCF53296.1 - 0.027 13.6 0.0 3.6 6.8 0.0 2.1 1 1 1 2 2 2 0 Telomere recombination FGGY_C PF02782.11 CCF53297.1 - 2.1e-45 154.7 0.0 3.4e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCF53297.1 - 3.1e-19 69.2 0.5 3.4e-10 39.6 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 CCF53297.1 - 4.4e-06 26.1 0.6 0.00031 20.1 0.2 2.4 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 CCF53297.1 - 0.0057 15.5 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Arginase PF00491.16 CCF53298.1 - 2.4e-82 276.3 0.0 3.3e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 CCF53298.1 - 0.13 12.4 0.3 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain GIY-YIG PF01541.19 CCF53299.1 - 7.8e-05 22.9 0.0 0.0003 21.1 0.0 2.0 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-rbx1 PF12678.2 CCF53299.1 - 0.033 14.2 0.6 0.19 11.8 0.4 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger zf-HC5HC2H PF13771.1 CCF53299.1 - 0.043 13.9 1.7 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.3 CCF53299.1 - 0.051 13.5 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 CCF53299.1 - 0.09 12.6 3.0 0.48 10.3 0.0 2.6 2 1 1 3 3 3 0 Ring finger domain Mito_carr PF00153.22 CCF53300.1 - 3.7e-34 116.2 8.4 1.2e-13 50.5 0.3 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein SBF PF01758.11 CCF53301.1 - 6.7e-45 152.8 16.6 6.8e-45 152.7 9.6 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family p450 PF00067.17 CCF53302.1 - 1.1e-54 185.7 0.0 1.9e-35 122.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Aa_trans PF01490.13 CCF53303.1 - 0.0022 16.5 0.3 0.0026 16.3 0.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.1 CCF53303.1 - 0.032 13.9 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus MatE PF01554.13 CCF53303.1 - 0.054 13.1 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 MatE Tetraspannin PF00335.15 CCF53303.1 - 0.078 12.2 4.0 0.12 11.5 2.7 1.3 1 1 0 1 1 1 0 Tetraspanin family DRMBL PF07522.9 CCF53304.1 - 8.2e-27 93.4 0.0 1.5e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCF53304.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCF53304.1 - 0.081 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PI-PLC-X PF00388.14 CCF53305.1 - 6.6e-48 161.8 0.0 1e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCF53305.1 - 1.5e-32 112.0 0.0 2.5e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CCF53305.1 - 0.001 18.8 2.0 0.041 13.7 0.2 3.6 3 1 0 3 3 3 1 C2 domain Peptidase_M50B PF13398.1 CCF53306.1 - 0.052 12.9 3.3 0.069 12.5 2.3 1.1 1 0 0 1 1 1 0 Peptidase M50B-like SET PF00856.23 CCF53307.1 - 2e-06 28.1 0.0 4.7e-05 23.7 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 CCF53307.1 - 0.023 14.3 0.2 0.44 10.2 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CCF53307.1 - 0.05 13.5 0.2 0.05 13.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 CCF53308.1 - 6.2e-29 100.8 30.6 3.1e-15 55.7 11.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF53308.1 - 4.6e-24 84.8 66.8 1.3e-18 66.8 31.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Oxidored_FMN PF00724.15 CCF53309.1 - 4.5e-43 147.5 0.0 9.3e-42 143.2 0.0 2.4 2 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family GST_N_3 PF13417.1 CCF53310.1 - 4.4e-26 90.9 0.0 7.9e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCF53310.1 - 3.9e-18 65.2 0.0 7.3e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CCF53310.1 - 1.3e-10 41.3 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF53310.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCF53310.1 - 0.051 14.0 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CCF53310.1 - 0.086 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Peptidase_S9 PF00326.16 CCF53311.1 - 0.00011 21.5 0.1 0.00019 20.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCF53311.1 - 0.00013 21.7 0.1 0.00046 19.9 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lactamase_B_2 PF12706.2 CCF53312.1 - 3.2e-29 101.8 0.0 5.6e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_31 PF13847.1 CCF53312.1 - 8.4e-13 48.1 0.0 2.3e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF53312.1 - 2.7e-11 44.0 0.0 7.7e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53312.1 - 2e-07 31.4 0.0 4.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Lactamase_B_3 PF13483.1 CCF53312.1 - 2.3e-07 30.6 0.3 1.2e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Methyltransf_11 PF08241.7 CCF53312.1 - 0.00038 20.8 0.0 0.0035 17.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF53312.1 - 0.00072 19.8 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF53312.1 - 0.00073 19.2 0.0 0.0036 17.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCF53312.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF53312.1 - 0.0012 18.9 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SinI PF08671.5 CCF53312.1 - 0.12 11.7 0.0 0.36 10.3 0.0 1.9 1 0 0 1 1 1 0 Anti-repressor SinI MTS PF05175.9 CCF53312.1 - 0.14 11.5 0.0 0.54 9.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain UPF0052 PF01933.13 CCF53313.1 - 2.6e-42 145.2 0.0 1.6e-25 90.0 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family UPF0052 GalP_UDP_transf PF01087.17 CCF53314.1 - 7e-68 228.2 0.7 1.2e-67 227.4 0.5 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCF53314.1 - 2.3e-45 154.1 0.0 4.4e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CCF53314.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 HIT domain DUF2781 PF10914.3 CCF53315.1 - 5.2e-35 120.4 3.9 6.2e-35 120.1 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.13 CCF53316.1 - 5.9e-05 22.8 13.7 0.00012 21.8 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 CCF53319.1 - 7e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1682 PF07946.9 CCF53320.1 - 1.2e-78 264.2 0.0 1.4e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DDHD PF02862.12 CCF53320.1 - 0.73 9.5 3.9 1.2 8.8 2.7 1.3 1 0 0 1 1 1 0 DDHD domain 4F5 PF04419.9 CCF53321.1 - 1.4e-08 35.3 9.5 1.4e-08 35.3 6.6 2.2 2 0 0 2 2 2 1 4F5 protein family HlyD PF00529.15 CCF53321.1 - 8.4 5.5 12.0 10 5.3 8.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein adh_short PF00106.20 CCF53322.1 - 1.4e-18 67.3 0.0 2.4e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF53322.1 - 1.2e-08 34.8 0.2 2.1e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF53322.1 - 3.1e-05 23.8 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCF53322.1 - 0.00048 19.6 0.0 0.0007 19.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCF53322.1 - 0.0013 18.7 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF4302 PF14135.1 CCF53322.1 - 0.0049 16.2 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4302) HTH_Tnp_IS1 PF12759.2 CCF53322.1 - 0.08 12.3 0.2 62 3.1 0.0 3.4 3 0 0 3 3 3 0 InsA C-terminal domain Pmp3 PF01679.12 CCF53323.1 - 6.6e-12 44.9 6.4 9.4e-12 44.4 4.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Thioredoxin_4 PF13462.1 CCF53324.1 - 3.3e-06 27.2 0.0 6.7e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 CCF53324.1 - 0.1 12.1 0.0 1.6 8.2 0.0 2.4 3 0 0 3 3 3 0 DSBA-like thioredoxin domain MFS_1 PF07690.11 CCF53325.1 - 2.6e-40 138.2 47.7 2.5e-39 135.0 30.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF53325.1 - 3.5e-15 55.5 11.5 3.5e-15 55.5 8.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 CCF53325.1 - 4.9e-11 41.5 9.6 4.9e-11 41.5 6.6 2.3 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF2619 PF10942.3 CCF53325.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) ADH_zinc_N PF00107.21 CCF53326.1 - 2.4e-18 65.9 0.4 4.7e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF53326.1 - 2.8e-17 63.8 1.2 1e-15 58.7 0.3 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF53326.1 - 9.5e-13 47.8 0.0 2.3e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.1 CCF53326.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PHBC_N PF12551.3 CCF53326.1 - 0.044 13.3 0.1 0.12 11.8 0.1 1.7 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal DAGK_cat PF00781.19 CCF53326.1 - 0.051 13.0 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain I_LWEQ PF01608.12 CCF53326.1 - 0.071 13.0 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 I/LWEQ domain Ribosomal_60s PF00428.14 CCF53327.1 - 0.017 15.4 0.3 0.019 15.3 0.2 1.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein FinO_N PF12602.3 CCF53327.1 - 5.9 7.2 6.9 1.6 9.1 1.6 1.9 1 1 1 2 2 2 0 Fertility inhibition protein N terminal Peptidase_S10 PF00450.17 CCF53328.1 - 4.6e-115 385.0 0.6 6.1e-115 384.6 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCF53328.1 - 0.0018 18.2 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 CCF53329.1 - 1.4e-84 284.7 0.2 1.9e-84 284.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RVT_2 PF07727.9 CCF53331.1 - 4.2e-32 111.0 0.0 7.2e-28 97.1 0.0 3.0 2 1 2 4 4 4 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF53332.1 - 7.3e-09 35.7 0.2 2.3e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCF53332.1 - 1.3e-06 27.9 0.8 1.3e-06 27.9 0.5 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCF53332.1 - 0.26 11.2 3.8 0.84 9.6 2.6 2.0 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.19 CCF53333.1 - 2e-60 204.6 12.7 8.4e-42 143.2 0.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF53333.1 - 1e-17 63.8 23.3 4.2e-09 35.5 3.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily GTP_EFTU PF00009.22 CCF53334.1 - 1.1e-46 158.6 0.0 1.6e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCF53334.1 - 2.8e-34 117.2 0.8 5e-34 116.4 0.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCF53334.1 - 4.3e-18 64.9 0.0 2.1e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCF53334.1 - 2.9e-06 27.2 0.2 5.4e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF53334.1 - 0.00026 20.9 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 CCF53334.1 - 0.00039 20.1 0.0 0.001 18.8 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II ICL PF00463.16 CCF53335.1 - 7.5e-190 631.5 0.5 8.9e-190 631.3 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCF53335.1 - 1.4e-10 40.8 0.0 3.6e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.4 CCF53335.1 - 0.031 14.1 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Methyltransf_16 PF10294.4 CCF53336.1 - 1.5e-14 53.8 0.1 4.1e-14 52.4 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCF53336.1 - 0.00076 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCF53336.1 - 0.017 15.6 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CCF53336.1 - 0.047 13.7 0.1 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Pet191_N PF10203.4 CCF53339.1 - 1.9e-26 91.8 3.5 2.2e-26 91.6 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CCF53339.1 - 0.28 10.9 2.3 8.6 6.2 0.1 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_5 PF12695.2 CCF53340.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_2 PF07727.9 CCF53341.1 - 5e-41 140.3 0.1 5.4e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APC_crr PF05923.7 CCF53341.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 APC cysteine-rich region rve PF00665.21 CCF53343.1 - 0.00086 19.4 0.0 0.002 18.2 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCF53343.1 - 0.025 14.2 0.6 0.047 13.3 0.4 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain BTB PF00651.26 CCF53345.1 - 1.5e-10 41.0 0.1 7.9e-09 35.4 0.1 2.9 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_16 PF00722.16 CCF53346.1 - 3.5e-07 29.7 0.0 5.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 MFS_1 PF07690.11 CCF53347.1 - 2.5e-33 115.2 34.7 2.5e-33 115.2 24.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCF53347.1 - 2.9e-06 25.8 1.5 4.4e-06 25.1 1.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCF53348.1 - 7.3e-60 202.8 22.0 9.2e-58 195.8 15.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53348.1 - 1.3e-12 47.0 41.5 1.3e-12 47.0 28.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.3 CCF53348.1 - 0.47 10.5 2.4 2.4 8.2 1.7 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF3437 PF11919.3 CCF53349.1 - 3.6e-32 109.9 0.0 1.8e-31 107.6 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CCF53349.1 - 4.6e-05 23.1 0.1 0.00061 19.6 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 CCF53349.1 - 0.0025 18.0 0.0 0.02 15.1 0.0 2.6 1 0 0 1 1 1 1 HEAT repeats Arm PF00514.18 CCF53349.1 - 0.003 17.3 0.5 0.015 15.0 0.0 2.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CCF53349.1 - 0.014 15.8 0.0 1.1 9.8 0.0 3.4 2 0 0 2 2 2 0 HEAT-like repeat DUF1546 PF07571.8 CCF53349.1 - 0.039 14.0 0.3 0.23 11.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 CCF53349.1 - 0.051 13.9 0.0 0.29 11.5 0.0 2.3 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Ras PF00071.17 CCF53350.1 - 6.1e-62 207.7 0.1 7.3e-62 207.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF53350.1 - 6e-20 71.9 0.0 8.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF53350.1 - 1.7e-12 46.9 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCF53350.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF53350.1 - 2.2e-05 23.9 0.1 9.1e-05 21.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCF53350.1 - 7.1e-05 22.9 0.0 0.00027 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CCF53350.1 - 0.0024 17.0 0.1 0.0059 15.7 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCF53350.1 - 0.0028 16.8 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 CCF53350.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 CCF53350.1 - 0.017 15.1 0.4 0.042 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 CCF53350.1 - 0.023 14.1 0.0 0.077 12.4 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CCF53350.1 - 0.025 13.7 0.0 0.061 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CCF53350.1 - 0.027 14.7 0.2 0.036 14.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CCF53350.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCF53350.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CCF53350.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 CCF53350.1 - 0.13 11.5 0.1 0.67 9.2 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B LIP PF03583.9 CCF53351.1 - 1.3e-68 231.3 0.0 2e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 CCF53351.1 - 0.0028 16.9 0.0 0.45 9.7 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CCF53351.1 - 0.086 12.6 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 CCF53353.1 - 6e-07 29.0 0.1 1.2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2413 PF10310.4 CCF53355.1 - 6.6e-76 255.9 5.1 1.2e-75 255.0 3.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) DUF883 PF05957.8 CCF53355.1 - 0.11 12.8 8.7 3.6 8.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Inositol_P PF00459.20 CCF53356.1 - 8.6e-57 192.4 0.7 1.3e-55 188.5 0.5 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C2H2_4 PF13894.1 CCF53357.1 - 3.6e-09 36.3 8.2 0.00051 20.1 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCF53357.1 - 1.7e-07 31.1 6.3 0.0052 17.0 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCF53357.1 - 0.043 13.9 7.5 0.29 11.3 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCF53357.1 - 0.11 12.8 12.4 0.58 10.5 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-LYAR PF08790.6 CCF53357.1 - 0.54 9.9 3.7 0.86 9.3 0.5 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.1 CCF53357.1 - 6.1 7.2 7.5 0.9 9.9 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Mito_carr PF00153.22 CCF53359.1 - 1.2e-59 197.9 1.7 6.7e-22 77.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps39_2 PF10367.4 CCF53362.1 - 1.6e-12 47.5 0.2 5.2e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CCF53362.1 - 0.0022 17.9 0.2 0.0098 15.9 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 CCF53362.1 - 0.0034 16.8 0.0 0.0091 15.4 0.0 1.8 1 1 0 1 1 1 1 CNH domain Haem_oxygenas_2 PF14518.1 CCF53362.1 - 0.067 13.3 0.1 2.4 8.3 0.1 2.7 2 0 0 2 2 2 0 Iron-containing redox enzyme AAA PF00004.24 CCF53363.1 - 5.4e-41 139.8 0.0 1e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCF53363.1 - 4e-28 97.1 0.0 1.9e-27 94.9 0.0 2.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CCF53363.1 - 2.5e-23 81.7 5.4 8.3e-23 80.0 3.8 2.0 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CCF53363.1 - 2.6e-06 27.6 0.3 0.00057 20.0 0.0 2.8 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCF53363.1 - 3.2e-05 23.4 0.0 7.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCF53363.1 - 3.4e-05 24.6 0.2 0.00022 22.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CCF53363.1 - 5.6e-05 22.0 0.3 0.00012 21.0 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 CCF53363.1 - 6.4e-05 22.8 0.0 0.00018 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF53363.1 - 7.7e-05 22.5 1.1 0.00036 20.4 0.0 2.5 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CCF53363.1 - 8.3e-05 21.7 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CCF53363.1 - 0.00011 22.3 0.1 0.015 15.4 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_5 PF07728.9 CCF53363.1 - 0.00012 21.7 0.0 0.00041 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF53363.1 - 0.00044 20.3 0.0 0.005 16.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCF53363.1 - 0.00094 18.6 0.2 0.24 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CCF53363.1 - 0.0015 18.4 0.1 0.009 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCF53363.1 - 0.0016 17.4 0.0 0.0045 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CCF53363.1 - 0.0071 15.5 0.0 0.02 14.0 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCF53363.1 - 0.0093 15.0 0.1 3.3 6.7 0.0 2.3 1 1 1 2 2 2 2 KaiC Zeta_toxin PF06414.7 CCF53363.1 - 0.013 14.5 0.2 0.57 9.2 0.0 2.4 1 1 1 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 CCF53363.1 - 0.045 13.2 0.0 0.47 9.9 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 CCF53363.1 - 0.047 12.5 0.2 2.6 6.7 0.0 2.5 3 0 0 3 3 3 0 AFG1-like ATPase PhoH PF02562.11 CCF53363.1 - 0.049 12.8 0.0 0.14 11.4 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 CCF53363.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCF53363.1 - 0.087 12.4 0.0 0.59 9.7 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 CCF53363.1 - 0.089 12.3 0.0 0.089 12.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 CCF53363.1 - 0.099 12.3 1.2 1.4 8.5 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 CCF53363.1 - 0.1 12.9 0.4 0.34 11.2 0.0 2.3 2 1 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCF53363.1 - 0.12 12.4 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 CCF53363.1 - 0.19 11.1 2.0 0.7 9.2 0.1 2.7 3 1 1 4 4 4 0 AAA-like domain Xpo1 PF08389.7 CCF53364.1 - 1.6e-22 80.0 0.0 3.5e-21 75.6 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CCF53364.1 - 1e-05 25.3 0.5 3e-05 23.8 0.3 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain ParcG PF10274.4 CCF53364.1 - 0.11 12.4 0.0 18 5.1 0.0 3.3 3 1 0 4 4 4 0 Parkin co-regulated protein DUF500 PF04366.7 CCF53365.1 - 2.7e-38 130.2 1.0 1.1e-37 128.3 0.7 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCF53365.1 - 3e-11 42.5 0.0 9.7e-11 40.8 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF53365.1 - 3.2e-09 36.2 0.0 6.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF53365.1 - 7.4e-09 34.9 0.0 1.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CoA_binding PF02629.14 CCF53366.1 - 3.2e-27 94.8 0.5 9.5e-27 93.3 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CCF53366.1 - 2.3e-21 75.9 0.1 4.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCF53366.1 - 6.3e-07 29.0 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CCF53366.1 - 0.00011 22.3 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 CCF53366.1 - 0.0041 17.6 0.0 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Utp12 PF04003.7 CCF53367.1 - 3.1e-12 46.3 1.1 1.2e-11 44.4 0.7 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 CCF53367.1 - 0.011 15.5 0.0 0.011 15.5 0.0 3.2 3 1 0 3 3 3 0 WD domain, G-beta repeat Pkinase PF00069.20 CCF53368.1 - 1.1e-72 244.3 0.0 1.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53368.1 - 4.4e-35 120.9 0.0 5.6e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF53368.1 - 0.017 14.1 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CCF53368.1 - 0.037 13.7 0.0 0.13 11.9 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCF53368.1 - 0.06 12.1 0.0 0.1 11.3 0.0 1.4 1 1 0 1 1 1 0 Seadornavirus VP7 Cut8_C PF08559.5 CCF53370.1 - 0.064 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Cut8 six-helix bundle PBP1_TM PF14812.1 CCF53370.1 - 3.8 7.8 7.8 0.43 10.9 2.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM PF00493.18 CCF53373.1 - 9.4e-129 428.9 0.0 1.3e-128 428.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCF53373.1 - 3.1e-23 82.5 0.1 8.1e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCF53373.1 - 6.9e-08 31.8 0.0 8.8e-07 28.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCF53373.1 - 0.0049 16.4 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF53373.1 - 0.007 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2201_N PF13203.1 CCF53373.1 - 0.64 9.1 5.5 1.1 8.4 3.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Arm PF00514.18 CCF53374.1 - 2.7e-11 42.8 26.4 4.7e-05 23.0 0.1 10.3 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CCF53374.1 - 0.0032 17.4 25.3 1.1 9.5 0.1 8.6 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 CCF53374.1 - 1.7 9.2 22.6 17 6.0 0.3 7.8 9 1 0 9 9 9 0 HEAT-like repeat Complex1_30kDa PF00329.14 CCF53375.1 - 2.7e-35 120.7 0.0 3.8e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.6 CCF53376.1 - 5.1e-61 205.9 0.2 6.7e-61 205.5 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Enkurin PF13864.1 CCF53376.1 - 0.2 11.8 5.0 0.44 10.7 3.5 1.6 1 0 0 1 1 1 0 Calmodulin-binding Nup54 PF13874.1 CCF53376.1 - 0.38 10.4 6.0 0.7 9.5 4.1 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MSP1_C PF07462.6 CCF53377.1 - 0.85 7.9 1.9 5.6 5.2 2.1 1.7 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1264 PF06884.6 CCF53378.1 - 4.7e-62 208.4 0.0 6e-62 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Zn_clus PF00172.13 CCF53379.1 - 2.7e-06 27.1 11.7 4.8e-06 26.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBS PF00571.23 CCF53380.1 - 6.7e-36 121.8 8.2 7.6e-09 35.2 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 CCF53380.1 - 1.4e-06 27.9 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 PB1 domain NYN PF01936.13 CCF53380.1 - 0.0055 16.9 0.1 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 NYN domain DUF2380 PF09533.5 CCF53380.1 - 0.26 10.6 2.6 17 4.7 0.0 2.8 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) DUF4288 PF14119.1 CCF53380.1 - 0.45 10.6 2.0 5.6 7.1 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4288) TGS PF02824.16 CCF53381.1 - 2.2e-19 69.0 0.0 4.3e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCF53381.1 - 1.1e-17 64.0 0.1 2.3e-17 63.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF53381.1 - 3.2e-12 45.9 0.0 6.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCF53381.1 - 1.4e-06 28.8 0.0 3.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CCF53381.1 - 0.0064 16.3 0.7 1.5 8.6 0.0 2.8 2 1 0 3 3 3 1 Dynamin family AIG1 PF04548.11 CCF53381.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.1 CCF53381.1 - 0.05 13.5 0.2 0.34 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain TAP_C PF03943.8 CCF53382.1 - 2.1e-13 49.4 0.1 4.1e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 CCF53382.1 - 3.6e-07 29.6 7.0 6.8e-05 22.3 0.5 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF53382.1 - 0.0069 16.1 1.6 0.028 14.1 1.1 2.2 1 1 0 1 1 1 1 Leucine rich repeat Spore_YunB PF09560.5 CCF53382.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) LRR_7 PF13504.1 CCF53382.1 - 0.33 11.3 2.3 13 6.5 0.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat DUF2486 PF10667.4 CCF53382.1 - 2.1 8.8 7.7 5.9 7.3 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) UvrD_C PF13361.1 CCF53385.1 - 3.4e-73 247.1 0.0 7.8e-42 143.9 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCF53385.1 - 2.1e-68 230.9 0.2 2.1e-68 230.9 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCF53385.1 - 1.6e-13 50.6 0.0 8.5e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCF53385.1 - 2.2e-12 46.5 0.0 6.4e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CCF53385.1 - 3.1e-05 23.6 0.0 0.55 9.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CCF53385.1 - 0.00046 19.8 0.4 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCF53385.1 - 0.021 14.9 0.1 3.4 7.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain PALP PF00291.20 CCF53386.1 - 2e-47 161.8 0.6 2.7e-47 161.4 0.4 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GTP_EFTU PF00009.22 CCF53387.1 - 9.2e-52 175.2 0.0 1.7e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCF53387.1 - 2e-22 78.7 0.0 4.2e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCF53387.1 - 1.1e-16 60.4 0.1 4.6e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCF53387.1 - 2.1e-08 34.1 0.0 8.8e-08 32.1 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCF53387.1 - 0.00035 20.5 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NPIP PF06409.6 CCF53389.1 - 0.0034 16.1 0.0 0.005 15.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex interacting protein (NPIP) SEEEED PF14797.1 CCF53389.1 - 0.0066 16.5 1.0 0.01 15.9 0.7 1.2 1 0 0 1 1 1 1 Serine-rich region of AP3B1, clathrin-adaptor complex HCO3_cotransp PF00955.16 CCF53390.1 - 3e-43 148.2 13.7 8.6e-25 87.3 2.4 3.0 1 1 1 2 2 2 2 HCO3- transporter family FHA PF00498.21 CCF53391.1 - 0.0019 18.2 0.0 0.016 15.3 0.0 2.5 2 1 0 2 2 2 1 FHA domain AMP-binding PF00501.23 CCF53396.1 - 4.6e-77 259.1 0.0 6.3e-77 258.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCF53396.1 - 1.6e-64 217.2 0.0 2.7e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCF53396.1 - 1.9e-14 53.6 0.0 5.7e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 CCF53396.1 - 4.8e-09 37.0 0.0 3.8e-08 34.1 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 CCF53396.1 - 2.2e-05 24.0 0.0 6.2e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 CCF53396.1 - 0.0014 17.5 0.1 0.02 13.7 0.1 2.2 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.14 CCF53396.1 - 0.0046 15.6 0.0 0.58 8.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_transf_28 PF03033.15 CCF53397.1 - 1.7e-15 57.0 0.0 2.5e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain DUF1688 PF07958.6 CCF53399.1 - 6.8e-158 525.6 0.0 8.7e-158 525.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF3692 PF12469.3 CCF53399.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein ABC2_membrane PF01061.19 CCF53400.1 - 8.6e-36 123.0 17.3 8.6e-36 123.0 12.0 2.4 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CCF53400.1 - 2.1e-25 89.6 0.0 3.7e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CCF53400.1 - 1.3e-06 27.7 24.8 1.3e-06 27.7 17.2 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CCF53400.1 - 7.4e-06 26.1 0.0 0.049 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCF53400.1 - 0.0017 19.1 0.0 0.0036 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCF53400.1 - 0.0046 16.4 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCF53400.1 - 0.0058 16.0 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCF53400.1 - 0.01 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CCF53400.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCF53400.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CCF53400.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CCF53400.1 - 0.021 14.5 0.2 0.042 13.5 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCF53400.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain hEGF PF12661.2 CCF53400.1 - 0.04 14.0 20.5 0.29 11.3 1.0 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF Miro PF08477.8 CCF53400.1 - 0.042 14.3 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein UPF0079 PF02367.12 CCF53400.1 - 0.058 13.0 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CCF53400.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCF53400.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 CCF53400.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CCF53400.1 - 0.12 12.6 0.2 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF3827 PF12877.2 CCF53400.1 - 0.28 9.2 0.1 0.53 8.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Hemerythrin PF01814.18 CCF53402.1 - 2.6e-16 59.9 1.4 4.2e-14 52.8 0.1 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain YhdB PF14148.1 CCF53402.1 - 0.027 14.2 0.2 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 YhdB-like protein LRR_4 PF12799.2 CCF53403.1 - 3.1e-23 80.9 29.0 1.8e-06 27.3 3.5 8.9 4 2 8 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF53403.1 - 3.2e-23 81.2 22.7 9.5e-07 28.4 0.8 6.7 6 1 1 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 CCF53403.1 - 3.7e-10 38.3 34.9 0.6 10.3 0.8 12.7 12 3 2 14 14 14 4 Leucine Rich Repeat LRR_9 PF14580.1 CCF53403.1 - 0.002 17.6 6.9 1.8 8.0 0.1 3.9 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 CCF53403.1 - 0.037 14.1 39.3 3 8.4 0.1 11.8 13 0 0 13 13 13 0 Leucine rich repeat LRR_6 PF13516.1 CCF53403.1 - 3.1 8.1 30.8 1.1 9.5 0.4 9.3 9 1 2 11 11 11 0 Leucine Rich repeat MAP65_ASE1 PF03999.7 CCF53404.1 - 6.6e-57 193.4 0.1 1.3e-51 175.9 0.0 2.2 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) BCDHK_Adom3 PF10436.4 CCF53405.1 - 5.1e-45 152.9 0.3 6.9e-45 152.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCF53405.1 - 9.4e-12 44.6 0.0 5.3e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGP_phosphatase PF09419.5 CCF53406.1 - 3.2e-48 163.2 0.1 7e-44 149.1 0.0 2.5 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase IL6 PF00489.12 CCF53406.1 - 0.088 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family DUF2373 PF10180.4 CCF53407.1 - 1e-14 53.8 0.2 3.5e-09 36.0 0.3 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Anti-adapt_IraP PF10796.4 CCF53407.1 - 0.14 12.5 0.2 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein TSP_1 PF00090.14 CCF53407.1 - 0.71 10.0 4.0 7 6.8 0.3 2.6 2 0 0 2 2 2 0 Thrombospondin type 1 domain SR-25 PF10500.4 CCF53407.1 - 3.3 7.1 48.3 0.2 11.0 27.8 2.7 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 CCF53407.1 - 3.3 5.2 15.9 5.1 4.6 11.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.7 CCF53407.1 - 3.6 5.8 47.4 0.42 8.9 14.3 2.7 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lum_binding PF00677.12 CCF53410.1 - 2.2e-29 101.1 0.1 4.4e-19 68.1 0.0 3.6 3 1 0 3 3 3 3 Lumazine binding domain DUF2249 PF10006.4 CCF53412.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Homoserine_dh PF00742.14 CCF53414.1 - 1.2e-44 152.1 0.0 1.7e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCF53414.1 - 7.1e-14 52.1 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain BUD22 PF09073.5 CCF53415.1 - 1.4e-82 278.0 47.6 1.4e-82 278.0 33.0 2.4 2 1 0 2 2 2 1 BUD22 Peptidase_M20 PF01546.23 CCF53416.1 - 3.9e-27 94.9 0.0 5.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 CCF53416.1 - 9.5e-05 22.2 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.9 CCF53416.1 - 0.00094 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain GMC_oxred_N PF00732.14 CCF53417.1 - 3.6e-61 206.9 0.0 5e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF53417.1 - 5.7e-38 130.4 0.2 1e-37 129.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCF53417.1 - 6.8e-06 25.2 1.1 2.4e-05 23.4 0.8 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCF53417.1 - 2.9e-05 24.0 0.0 0.043 13.6 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF53417.1 - 0.00038 19.4 0.0 0.0011 17.9 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CCF53417.1 - 0.0026 17.8 0.3 2.5 8.1 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF53417.1 - 0.0069 15.2 1.7 0.047 12.5 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CCF53417.1 - 0.0086 15.1 0.1 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CCF53417.1 - 0.012 15.5 0.1 0.028 14.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCF53417.1 - 0.043 13.5 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DLH PF01738.13 CCF53418.1 - 1.2e-19 70.5 0.5 1.4e-19 70.2 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCF53418.1 - 3.2e-05 23.7 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family FadA PF09403.5 CCF53418.1 - 0.039 13.9 0.5 0.039 13.9 0.4 1.7 2 0 0 2 2 2 0 Adhesion protein FadA DUF2048 PF09752.4 CCF53418.1 - 0.055 12.3 0.1 0.084 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CCF53418.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Bot1p PF12298.3 CCF53419.1 - 0.013 15.4 1.2 0.024 14.5 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein PspB PF06667.7 CCF53419.1 - 0.044 13.7 0.1 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B DUF3687 PF12459.3 CCF53419.1 - 0.23 10.7 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Pyr_redox_3 PF13738.1 CCF53420.1 - 1.4e-29 103.6 0.0 4.1e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCF53420.1 - 1.6e-16 59.5 0.0 1.2e-15 56.7 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 CCF53420.1 - 6.2e-12 45.3 0.0 6.6e-10 38.8 0.0 3.3 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCF53420.1 - 1e-08 34.5 0.1 5.3e-07 28.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCF53420.1 - 4.9e-07 29.8 0.1 1.5e-05 24.9 0.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF53420.1 - 2.5e-06 27.8 0.2 0.0078 16.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF53420.1 - 6.2e-05 22.2 0.1 0.00016 20.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CCF53420.1 - 0.00013 21.0 0.8 0.0044 15.9 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCF53420.1 - 0.00068 18.6 0.2 0.13 11.1 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.15 CCF53420.1 - 0.0052 16.8 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CCF53420.1 - 0.0078 15.1 0.0 0.032 13.0 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 CCF53420.1 - 0.01 15.6 0.2 3 7.6 0.0 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 CCF53420.1 - 0.016 14.3 0.0 0.35 9.9 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Mqo PF06039.10 CCF53420.1 - 0.016 13.3 0.0 0.46 8.6 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_7 PF13241.1 CCF53420.1 - 0.049 13.8 0.0 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 CCF53420.1 - 0.082 11.9 0.0 0.97 8.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Amidohydro_4 PF13147.1 CCF53421.1 - 7.6e-12 45.8 0.1 5.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 CCF53421.1 - 1.1e-08 35.1 0.0 0.00065 19.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CCF53421.1 - 6.2e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCF53421.1 - 0.00042 19.6 0.3 0.0015 17.8 0.0 2.0 3 0 0 3 3 3 1 Amidohydrolase family DUF3605 PF12239.3 CCF53422.1 - 7.2e-28 97.4 0.1 4.1e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) BcrAD_BadFG PF01869.15 CCF53423.1 - 2.4e-11 43.4 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Glucosamine_iso PF01182.15 CCF53424.1 - 3.9e-24 85.4 0.0 5.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Arb2 PF09757.4 CCF53424.1 - 0.11 11.9 0.1 2.3 7.6 0.0 2.4 2 1 0 2 2 2 0 Arb2 domain Zn_clus PF00172.13 CCF53425.1 - 7.6e-08 32.1 9.3 1.7e-07 31.0 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PGM_PMM_I PF02878.11 CCF53426.1 - 4.3e-35 120.2 0.0 6.4e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCF53426.1 - 2e-16 60.2 0.0 4.8e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CCF53426.1 - 1.2e-11 44.6 0.1 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCF53426.1 - 9.7e-09 35.1 0.1 3.1e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Lipase_3 PF01764.20 CCF53427.1 - 4.4e-12 45.7 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Herpes_TAF50 PF03326.8 CCF53427.1 - 2 7.2 7.6 5.6 5.8 2.6 2.2 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) DUF1479 PF07350.7 CCF53428.1 - 2.7e-141 470.8 0.0 3.2e-141 470.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) CAP_N PF01213.14 CCF53428.1 - 0.55 9.4 3.0 0.89 8.7 2.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.17 CCF53429.1 - 5.6e-55 186.7 0.0 7.3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDK2AP PF09806.4 CCF53431.1 - 0.31 11.2 6.7 1 9.5 4.6 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Sulfate_transp PF00916.15 CCF53431.1 - 0.58 9.1 6.7 0.51 9.2 3.9 1.6 2 0 0 2 2 2 0 Sulfate transporter family APS_kinase PF01583.15 CCF53433.1 - 1.9e-69 232.3 0.0 2.2e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCF53433.1 - 9.7e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCF53433.1 - 5.9e-06 27.0 0.0 1.2e-05 26.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF53433.1 - 1.1e-05 25.6 0.1 2.8e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCF53433.1 - 0.00026 20.2 0.0 0.00032 20.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCF53433.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCF53433.1 - 0.0021 17.1 0.0 0.014 14.5 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 CCF53433.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CCF53433.1 - 0.053 13.8 0.2 0.063 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCF53433.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.7 CCF53433.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein MaoC_dehydrat_N PF13452.1 CCF53434.1 - 9.4e-10 38.3 0.1 9.5e-06 25.4 0.0 2.8 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase SelR PF01641.13 CCF53435.1 - 6.2e-51 171.2 0.1 8.3e-51 170.8 0.1 1.1 1 0 0 1 1 1 1 SelR domain WD40 PF00400.27 CCF53436.1 - 1.6e-16 59.4 17.7 8.2e-09 35.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40 PF00400.27 CCF53437.1 - 1.7e-09 37.1 9.0 0.16 11.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat MBOAT_2 PF13813.1 CCF53438.1 - 0.00049 20.1 2.8 0.0012 18.9 1.6 1.9 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DEAD PF00270.24 CCF53439.1 - 1.8e-44 151.2 0.0 3.6e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF53439.1 - 2.4e-27 94.5 0.0 9.7e-26 89.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF53439.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCF53439.1 - 0.0039 16.3 0.0 0.0039 16.3 0.0 3.1 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SR-25 PF10500.4 CCF53439.1 - 0.013 15.0 23.6 0.022 14.2 16.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PH_6 PF15406.1 CCF53439.1 - 0.28 11.2 0.1 0.28 11.2 0.0 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain MIP-T3 PF10243.4 CCF53439.1 - 4.3 5.6 23.8 5.7 5.2 16.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 adh_short PF00106.20 CCF53440.1 - 1.4e-13 51.1 0.0 4.7e-10 39.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCF53440.1 - 2.5e-06 27.4 0.5 9.5e-06 25.5 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF53440.1 - 1.5e-05 24.6 0.0 0.00025 20.7 0.0 2.1 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 CCF53440.1 - 0.0051 16.8 0.1 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RcsC PF09456.5 CCF53440.1 - 0.13 11.9 0.1 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) EF-hand_5 PF13202.1 CCF53441.1 - 0.08 12.3 0.4 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.27 CCF53441.1 - 0.13 11.6 1.2 0.23 10.8 0.2 1.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CCF53441.1 - 0.17 11.5 1.7 0.55 9.8 0.5 2.1 2 0 0 2 2 2 0 EF-hand domain pair Ras PF00071.17 CCF53442.1 - 1.5e-52 177.2 0.0 1.8e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF53442.1 - 3.9e-19 69.3 0.0 5.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF53442.1 - 2.3e-11 43.2 0.0 3e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF53442.1 - 5e-06 26.0 0.0 7.5e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF53442.1 - 9.2e-06 24.9 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF53442.1 - 0.00075 19.4 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCF53442.1 - 0.002 18.1 0.1 0.0038 17.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCF53442.1 - 0.0026 17.9 0.0 0.005 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CCF53442.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit KaiC PF06745.8 CCF53442.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CCF53442.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 CCF53442.1 - 0.021 14.3 0.0 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 CCF53442.1 - 0.027 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 CCF53442.1 - 0.092 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.12 CCF53442.1 - 0.15 11.5 0.0 3.5 7.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.1 CCF53442.1 - 0.19 10.7 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RWD PF05773.17 CCF53443.1 - 5.7e-20 71.3 0.2 1.3e-19 70.1 0.2 1.6 1 0 0 1 1 1 1 RWD domain TrwC PF08751.6 CCF53443.1 - 2.2 7.6 11.5 0.086 12.2 3.2 1.9 2 0 0 2 2 2 0 TrwC relaxase HlyIII PF03006.15 CCF53444.1 - 1.4e-54 184.8 20.4 1.4e-54 184.8 14.1 2.5 2 1 0 2 2 2 1 Haemolysin-III related EBP PF05241.7 CCF53444.1 - 2.8e-05 23.2 5.7 2.8e-05 23.2 3.9 2.0 2 0 0 2 2 2 1 Emopamil binding protein Helicase_IV_N PF12462.3 CCF53445.1 - 0.037 13.6 2.7 0.077 12.6 0.5 2.2 1 1 1 2 2 2 0 DNA helicase IV / RNA helicase N terminal Abhydrolase_5 PF12695.2 CCF53447.1 - 3.3e-09 36.6 0.0 2e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF53447.1 - 1.3e-06 28.4 0.4 2.5e-06 27.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PhoPQ_related PF10142.4 CCF53447.1 - 0.096 11.1 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Cyt-b5 PF00173.23 CCF53448.1 - 1.1e-23 82.8 0.1 1.1e-23 82.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Init_tRNA_PT PF04179.7 CCF53449.1 - 1.5e-127 426.2 0.0 2.2e-127 425.6 0.0 1.2 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPc PF00782.15 CCF53449.1 - 0.00036 20.1 0.0 0.00096 18.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCF53449.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HORMA PF02301.13 CCF53450.1 - 1.7e-11 43.9 0.0 3.5e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 HORMA domain E1-E2_ATPase PF00122.15 CCF53452.1 - 3.3e-66 222.6 3.1 5.4e-66 221.9 2.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF53452.1 - 1.2e-34 119.4 2.8 1.2e-34 119.4 2.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF53452.1 - 7e-31 108.3 0.0 9.5e-25 88.2 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF53452.1 - 5.3e-18 64.7 0.1 1e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCF53452.1 - 5.2e-15 54.6 0.0 1.4e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCF53452.1 - 7.9e-13 49.0 1.0 2.3e-12 47.4 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 CCF53452.1 - 0.00011 20.8 1.7 0.00017 20.2 0.0 1.9 2 0 0 2 2 2 1 DctM-like transporters Hydrolase_3 PF08282.7 CCF53452.1 - 0.00056 19.5 1.0 0.0057 16.2 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MaoC_dehydratas PF01575.14 CCF53454.1 - 1.6e-26 92.1 0.0 7.1e-26 90.0 0.0 2.1 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CCF53454.1 - 2.7e-11 43.3 0.0 6.6e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase BAR PF03114.13 CCF53455.1 - 7.2e-44 150.0 5.1 1e-43 149.4 3.5 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 CCF53455.1 - 2.5e-15 55.7 0.1 7.6e-15 54.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CCF53455.1 - 3.1e-15 55.2 0.0 6.5e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCF53455.1 - 2.8e-11 42.7 0.0 6.6e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 CCF53455.1 - 0.0022 17.3 0.5 0.0031 16.8 0.3 1.2 1 0 0 1 1 1 1 FAM92 protein Prefoldin PF02996.12 CCF53455.1 - 0.026 14.1 0.6 0.32 10.6 0.0 2.5 2 1 0 2 2 2 0 Prefoldin subunit DUF1295 PF06966.7 CCF53457.1 - 1.2e-49 168.7 0.6 1.7e-49 168.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CCF53457.1 - 6.4e-05 23.0 0.0 0.00029 20.9 0.0 2.1 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CCF53457.1 - 0.00038 20.2 1.2 0.00065 19.4 0.0 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 CCF53457.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltransf_16 PF10294.4 CCF53458.1 - 5.4e-15 55.2 0.0 7.7e-14 51.5 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCF53458.1 - 0.00075 20.0 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF53458.1 - 0.045 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53458.1 - 0.085 13.3 0.2 0.3 11.6 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain Metallopep PF12044.3 CCF53459.1 - 2.6e-92 309.5 0.0 4.1e-73 246.2 0.0 2.1 2 0 0 2 2 2 2 Putative peptidase family Jacalin PF01419.12 CCF53459.1 - 0.015 15.1 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 0 Jacalin-like lectin domain Xan_ur_permease PF00860.15 CCF53460.1 - 1.1e-24 86.7 29.7 1.1e-24 86.6 18.3 2.2 2 1 0 2 2 2 1 Permease family Aldose_epim PF01263.15 CCF53462.1 - 9.3e-32 110.3 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2256 PF10013.4 CCF53463.1 - 4.5e-11 42.3 3.0 6.9e-11 41.7 2.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 CCF53463.1 - 0.026 13.7 0.1 0.066 12.5 0.1 1.6 1 0 0 1 1 1 0 Life-span regulatory factor RIC1 PF07064.8 CCF53464.1 - 2.1e-69 233.8 0.0 2.1e-67 227.3 0.0 2.2 1 1 0 1 1 1 1 RIC1 WD40 PF00400.27 CCF53464.1 - 0.048 13.5 2.4 1.7 8.6 0.3 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF914 PF06027.7 CCF53464.1 - 0.11 11.3 0.0 0.52 9.0 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) Apc4_WD40 PF12894.2 CCF53464.1 - 0.13 11.8 0.0 17 5.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQ-loop PF04193.9 CCF53465.1 - 6.4e-34 115.3 8.6 3.5e-17 61.7 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat ECH PF00378.15 CCF53466.1 - 4.2e-17 62.0 0.0 7.2e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 CCF53466.1 - 5.8e-09 35.7 0.0 5e-08 32.6 0.0 2.3 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CCF53466.1 - 6.2e-06 26.2 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 CCF53467.1 - 5.5e-32 110.8 24.6 5.5e-32 110.8 17.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3094 PF11293.3 CCF53467.1 - 8.5 5.9 8.3 0.36 10.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) DUF2404 PF10296.4 CCF53468.1 - 0.081 13.0 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) RVT_2 PF07727.9 CCF53470.1 - 3e-20 72.2 0.0 4.6e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1829 PF08862.5 CCF53470.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF1829 CIAPIN1 PF05093.8 CCF53471.1 - 2.2e-30 104.6 6.5 9.2e-30 102.6 4.5 2.0 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis WBS_methylT PF12589.3 CCF53472.1 - 3.3e-18 65.9 8.4 3.3e-18 65.9 5.9 1.8 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CCF53472.1 - 7.2e-11 42.4 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF53472.1 - 9.2e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF53472.1 - 2.9e-06 27.5 0.0 6.6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53472.1 - 8.5e-06 26.1 0.0 2.3e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF53472.1 - 1.1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF53472.1 - 1.7e-05 25.3 0.0 2.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 CCF53472.1 - 0.0079 16.3 0.0 0.061 13.4 0.0 2.2 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 CCF53472.1 - 0.0083 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AFG1_ATPase PF03969.11 CCF53473.1 - 2.8e-54 184.3 0.1 4.4e-47 160.6 0.0 4.6 2 1 0 3 3 3 2 AFG1-like ATPase DnaJ PF00226.26 CCF53473.1 - 1.4e-19 69.5 1.0 3.6e-19 68.2 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain AAA_16 PF13191.1 CCF53473.1 - 0.00048 20.1 1.0 0.0043 17.0 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCF53473.1 - 0.0024 18.0 0.0 0.029 14.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF53473.1 - 0.02 14.6 0.1 0.33 10.7 0.0 2.9 3 0 0 3 3 3 0 Part of AAA domain Mg_chelatase PF01078.16 CCF53473.1 - 0.069 12.2 0.5 0.29 10.2 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 CCF53473.1 - 0.2 11.8 0.0 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GPI-anchored PF10342.4 CCF53478.1 - 7.5e-13 48.7 4.3 7.5e-13 48.7 3.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cna_B PF05738.8 CCF53478.1 - 0.011 15.4 0.1 0.011 15.4 0.1 2.5 2 1 1 3 3 3 0 Cna protein B-type domain Fungal_trans PF04082.13 CCF53479.1 - 2.4e-35 121.6 0.0 4.7e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53479.1 - 2.2e-08 33.8 8.6 4.2e-08 32.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Serglycin PF04360.7 CCF53479.1 - 0.014 15.1 0.7 0.036 13.7 0.5 1.7 1 0 0 1 1 1 0 Serglycin KR PF08659.5 CCF53480.1 - 0.0098 15.5 4.0 0.072 12.7 0.5 2.4 2 0 0 2 2 2 2 KR domain Peptidase_S9 PF00326.16 CCF53482.1 - 8.8e-37 126.3 0.0 1.8e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PIG-H PF10181.4 CCF53482.1 - 1.5e-12 46.9 0.0 3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Abhydrolase_5 PF12695.2 CCF53482.1 - 2.2e-08 33.9 0.1 4.6e-05 23.2 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 CCF53482.1 - 4.4e-07 29.4 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 CCF53482.1 - 0.001 19.0 0.0 0.0047 16.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCF53482.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) YscJ_FliF PF01514.12 CCF53482.1 - 0.043 12.9 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family BAAT_C PF08840.6 CCF53482.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Kinesin PF00225.18 CCF53483.1 - 6e-112 373.6 0.0 9.4e-112 373.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL6 PF01763.11 CCF53483.1 - 0.0019 16.4 7.7 0.0028 15.9 4.8 1.6 1 1 0 1 1 1 1 Herpesvirus UL6 like APG6 PF04111.7 CCF53483.1 - 0.22 10.5 5.3 0.55 9.2 3.7 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Med9 PF07544.8 CCF53483.1 - 0.28 10.9 2.9 13 5.5 0.0 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 eRF1_1 PF03463.10 CCF53484.1 - 2.5e-55 185.6 0.0 3.7e-55 185.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 CCF53484.1 - 7.9e-24 84.4 0.0 1.5e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCF53484.1 - 2.4e-23 82.5 0.0 5.4e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 Ribosomal_60s PF00428.14 CCF53484.1 - 0.022 15.1 6.5 0.022 15.1 4.5 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CCF53484.1 - 0.11 12.9 7.4 0.23 12.0 5.1 1.5 1 0 0 1 1 1 0 Chorion family 2 L51_S25_CI-B8 PF05047.11 CCF53485.1 - 9e-13 47.7 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RAI16-like PF10257.4 CCF53486.1 - 5.5e-65 219.6 0.0 2.2e-64 217.6 0.0 1.9 1 1 1 2 2 2 1 Retinoic acid induced 16-like protein ATP12 PF07542.6 CCF53487.1 - 1.9e-37 127.9 0.0 2.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pex24p PF06398.6 CCF53488.1 - 9e-25 87.2 18.4 1.2e-16 60.5 0.0 3.1 3 0 0 3 3 3 3 Integral peroxisomal membrane peroxin PIG-S PF10510.4 CCF53489.1 - 1.3e-132 443.1 4.8 1.6e-132 442.8 3.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein ATP-gua_PtransN PF02807.10 CCF53489.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain Aldo_ket_red PF00248.16 CCF53491.1 - 1.2e-53 181.8 0.0 1.4e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCHC PF00098.18 CCF53492.1 - 0.0012 18.6 0.6 0.0021 17.9 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCF53492.1 - 0.55 9.9 2.3 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 Zinc knuckle FUSC_2 PF13515.1 CCF53493.1 - 3.7e-22 78.6 2.6 3.7e-22 78.6 1.8 2.8 2 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CCF53493.1 - 2.4e-18 66.0 0.0 1.2e-11 43.9 0.0 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CCF53493.1 - 3.5e-12 45.6 2.2 3.5e-12 45.6 1.5 3.8 3 1 1 4 4 4 1 Fusaric acid resistance protein family DUF2421 PF10334.4 CCF53493.1 - 7.5e-10 38.8 0.0 3.4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CCF53493.1 - 0.0012 17.6 1.5 0.016 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF939 PF06081.6 CCF53493.1 - 0.007 16.2 1.4 0.007 16.2 1.0 3.0 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF939) DUF1469 PF07332.6 CCF53493.1 - 0.18 11.5 5.4 0.62 9.8 3.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Zn_clus PF00172.13 CCF53494.1 - 0.00076 19.3 8.2 0.0021 17.9 5.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec39 PF08314.6 CCF53495.1 - 1.3e-49 168.8 1.0 2.5e-49 167.8 0.0 1.8 2 0 0 2 2 2 1 Secretory pathway protein Sec39 Med21 PF11221.3 CCF53496.1 - 4.4e-14 52.6 3.5 7.1e-14 51.9 2.4 1.3 1 1 0 1 1 1 1 Subunit 21 of Mediator complex IncA PF04156.9 CCF53496.1 - 0.0091 15.6 0.7 0.012 15.2 0.5 1.2 1 0 0 1 1 1 1 IncA protein ERM PF00769.14 CCF53496.1 - 0.017 14.7 0.5 0.018 14.5 0.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BRE1 PF08647.6 CCF53496.1 - 0.041 13.8 0.4 0.079 12.9 0.2 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase ADIP PF11559.3 CCF53496.1 - 0.051 13.4 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.1 CCF53496.1 - 0.081 12.2 1.5 0.19 11.0 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1664 PF07889.7 CCF53496.1 - 0.11 12.2 1.2 0.21 11.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-R PF06729.7 CCF53496.1 - 0.12 12.0 1.1 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 Kinetochore component, CENP-R Enkurin PF13864.1 CCF53496.1 - 0.13 12.4 1.1 0.28 11.3 0.7 1.6 1 1 0 1 1 1 0 Calmodulin-binding CENP-F_leu_zip PF10473.4 CCF53496.1 - 0.13 12.0 2.3 0.26 11.1 1.3 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CCF53496.1 - 0.2 11.1 1.2 4.4 6.8 0.6 2.3 2 0 0 2 2 2 0 Septum formation initiator rve PF00665.21 CCF53498.1 - 6.2e-09 35.9 0.0 9.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF53499.1 - 9.8e-38 129.5 0.0 1.2e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ceramidase PF05875.7 CCF53500.1 - 0.042 12.9 0.2 0.049 12.7 0.2 1.2 1 0 0 1 1 1 0 Ceramidase ICMT PF04140.9 CCF53501.1 - 4.4e-27 94.1 0.3 1e-26 92.9 0.2 1.7 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCF53501.1 - 6e-16 58.4 0.7 1.4e-15 57.3 0.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCF53501.1 - 2.2e-05 23.8 1.7 2.9e-05 23.4 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 CCF53501.1 - 0.00015 21.2 3.9 0.00034 20.0 2.7 1.7 1 1 0 1 1 1 1 NnrU protein TRP PF06011.7 CCF53502.1 - 4.5e-73 246.2 13.8 7.6e-73 245.5 9.5 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF4231 PF14015.1 CCF53502.1 - 5.6 6.9 13.2 2.4 8.1 2.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Zn_clus PF00172.13 CCF53503.1 - 5.9e-05 22.8 11.8 0.00012 21.8 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 CCF53503.1 - 3.9 5.5 25.7 6 4.9 17.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CCF53503.1 - 4.7 6.1 6.6 6.3 5.7 3.9 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DUF3808 PF10300.4 CCF53504.1 - 4.1e-82 276.2 1.4 1.6e-81 274.2 1.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 CCF53504.1 - 0.0012 18.7 8.2 0.024 14.5 0.5 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 CCF53504.1 - 0.0028 17.9 0.4 0.041 14.3 0.3 3.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCF53504.1 - 0.044 13.4 8.9 1.5 8.5 0.1 4.4 3 1 1 4 4 4 0 TPR repeat TPR_14 PF13428.1 CCF53504.1 - 0.12 13.0 2.3 3 8.7 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCF53504.1 - 0.65 9.9 8.9 0.089 12.6 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF53504.1 - 1.1 8.9 4.9 1.2 8.8 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.7 CCF53504.1 - 2.7 5.7 12.3 4.1 5.2 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCF53504.1 - 3.9 5.8 13.3 8.1 4.7 9.2 1.5 1 0 0 1 1 1 0 Daxx Family Ribosomal_S18 PF01084.15 CCF53505.1 - 1.6e-17 63.0 0.1 3.4e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 DNA_pol3_tau_4 PF12168.3 CCF53505.1 - 0.38 11.2 2.3 0.86 10.0 1.6 1.5 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding WD40 PF00400.27 CCF53506.1 - 3.7e-12 45.6 22.2 0.0011 18.7 0.1 7.0 6 1 0 6 6 6 3 WD domain, G-beta repeat PPP4R2 PF09184.6 CCF53506.1 - 0.0035 16.9 10.0 0.0043 16.6 6.9 1.1 1 0 0 1 1 1 1 PPP4R2 MMS1_N PF10433.4 CCF53506.1 - 0.007 14.5 0.0 0.011 13.9 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term FAM165 PF14981.1 CCF53506.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 FAM165 family CDC45 PF02724.9 CCF53506.1 - 0.035 12.1 9.7 0.047 11.7 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 CCF53506.1 - 0.084 12.3 16.9 0.17 11.3 11.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin RAB3GAP2_N PF14655.1 CCF53506.1 - 0.12 11.3 0.0 0.39 9.6 0.0 1.8 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1551 PF07585.6 CCF53506.1 - 0.13 11.1 0.1 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1551) Nop14 PF04147.7 CCF53506.1 - 0.28 9.0 17.7 0.38 8.6 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCF53506.1 - 0.54 8.6 18.1 0.73 8.2 12.6 1.1 1 0 0 1 1 1 0 Daxx Family BTV_NS2 PF04514.7 CCF53506.1 - 0.63 8.8 8.3 0.87 8.3 5.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Prog_receptor PF02161.10 CCF53506.1 - 0.73 8.5 2.6 0.95 8.2 1.8 1.2 1 0 0 1 1 1 0 Progesterone receptor SDA1 PF05285.7 CCF53506.1 - 0.78 8.9 16.1 1.1 8.5 11.2 1.1 1 0 0 1 1 1 0 SDA1 TEX19 PF15553.1 CCF53506.1 - 0.78 9.5 4.7 1.4 8.8 3.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Sporozoite_P67 PF05642.6 CCF53506.1 - 0.79 7.5 6.6 1 7.1 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP_sp32 PF07222.7 CCF53506.1 - 0.9 8.6 4.0 26 3.8 3.5 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 RXT2_N PF08595.6 CCF53506.1 - 1.4 8.7 10.6 2.5 7.9 7.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 CCF53506.1 - 2.2 7.8 15.7 3.4 7.2 10.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 CCF53506.1 - 2.4 7.8 8.9 4.1 7.0 6.2 1.3 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 CCF53506.1 - 3.1 6.1 12.1 4.3 5.6 8.4 1.1 1 0 0 1 1 1 0 Hsp90 protein RNA_pol_Rpc4 PF05132.9 CCF53506.1 - 3.9 7.4 5.3 6.6 6.7 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 VID27 PF08553.5 CCF53506.1 - 4.2 5.4 12.5 5.6 5.0 8.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 CCF53506.1 - 4.3 5.9 14.8 5.7 5.5 10.2 1.1 1 0 0 1 1 1 0 Paf1 YqfQ PF14181.1 CCF53506.1 - 6.2 6.8 7.0 10 6.1 4.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 CCF53506.1 - 6.4 5.6 13.6 9.4 5.1 9.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 CCF53506.1 - 7.2 5.7 17.8 3.9 6.6 10.9 1.6 2 0 0 2 2 2 0 NOA36 protein DUF4366 PF14283.1 CCF53506.1 - 8.9 5.6 15.4 13 5.0 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1510 PF07423.6 CCF53506.1 - 9.2 5.5 14.9 14 4.9 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cactin_mid PF10312.4 CCF53507.1 - 2.8e-65 219.1 8.0 7.9e-65 217.7 5.5 1.8 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 CCF53507.1 - 1.5e-57 192.6 5.1 2.9e-57 191.6 3.6 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AD PF09793.4 CCF53508.1 - 7.1e-22 77.0 0.0 1.3e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain Patched PF02460.13 CCF53509.1 - 3e-56 190.8 1.4 2.2e-29 102.0 0.0 2.6 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CCF53509.1 - 2.2e-42 144.0 11.9 1.2e-21 76.7 0.3 3.5 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 CCF53509.1 - 0.017 14.7 5.5 0.038 13.6 3.8 1.5 1 0 0 1 1 1 0 Folate receptor family ACR_tran PF00873.14 CCF53509.1 - 0.25 8.6 1.3 0.37 8.1 0.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family CHZ PF09649.5 CCF53511.1 - 4.7e-12 44.9 0.2 4.7e-12 44.9 0.1 3.0 4 1 0 4 4 4 1 Histone chaperone domain CHZ PBP_like PF12727.2 CCF53511.1 - 0.0045 15.9 0.2 0.0057 15.6 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain Sporozoite_P67 PF05642.6 CCF53511.1 - 7 4.3 8.1 7.1 4.3 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 CCF53511.1 - 7.8 4.2 18.6 9.1 4.0 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpb4 PF03874.11 CCF53512.1 - 9.5e-24 83.6 0.7 1.4e-23 83.1 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 CCF53513.1 - 1e-38 129.8 8.5 3e-09 36.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CCF53513.1 - 2.9e-25 88.0 10.5 4.6e-25 87.4 7.3 1.3 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 CCF53513.1 - 0.00019 20.2 0.1 0.57 8.8 0.0 4.1 3 1 1 5 5 5 1 Nup133 N terminal like eIF2A PF08662.6 CCF53513.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCF53513.1 - 0.0064 14.6 0.5 5.7 4.9 0.0 3.6 2 2 1 3 3 3 2 Nucleoporin Nup120/160 EIIA-man PF03610.11 CCF53513.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 PTS system fructose IIA component CBFB_NFYA PF02045.10 CCF53514.1 - 2.2e-27 95.3 10.7 2.2e-27 95.3 7.5 2.5 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ThuA PF06283.6 CCF53515.1 - 5.2e-42 143.9 0.0 7.7e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose utilisation Kelch_3 PF13415.1 CCF53516.1 - 5.9e-30 102.7 4.7 1.7e-07 31.2 0.0 7.0 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CCF53516.1 - 2.3e-28 97.7 3.9 4.6e-06 26.3 0.2 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 CCF53516.1 - 5.3e-23 80.6 0.0 5.3e-23 80.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 CCF53516.1 - 2.8e-15 55.8 4.9 5.7e-06 26.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 CCF53516.1 - 1.8e-13 49.6 0.5 0.0043 16.7 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CCF53516.1 - 1.9e-13 49.9 7.9 0.00044 20.3 0.1 5.1 3 2 2 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CCF53516.1 - 9.4e-13 47.4 4.1 2.7e-05 23.5 0.0 4.7 4 1 0 4 4 4 3 Kelch motif LPP20 PF02169.11 CCF53516.1 - 2.1 8.5 7.6 1.6 8.8 2.0 2.4 2 0 0 2 2 2 0 LPP20 lipoprotein ECH PF00378.15 CCF53517.1 - 2.6e-20 72.6 0.0 5.4e-18 64.9 0.0 2.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1731 PF08338.6 CCF53517.1 - 0.07 12.6 0.2 0.16 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) MMR1 PF08505.5 CCF53519.1 - 0.14 12.1 0.9 0.17 11.8 0.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Serglycin PF04360.7 CCF53519.1 - 0.71 9.5 5.6 2 8.1 3.9 1.8 1 1 0 1 1 1 0 Serglycin Actin PF00022.14 CCF53520.1 - 5.7e-132 439.8 0.0 6.5e-132 439.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCF53520.1 - 0.0001 21.0 0.0 0.0019 16.8 0.0 2.3 1 1 0 1 1 1 1 MreB/Mbl protein RVT_2 PF07727.9 CCF53521.1 - 1.6e-23 82.9 0.1 5.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1077 PF06417.7 CCF53522.1 - 1.7e-46 156.6 1.1 2.2e-46 156.2 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DHQ_synthase PF01761.15 CCF53523.1 - 9.3e-50 168.9 0.0 1.3e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 CCF53523.1 - 5.2e-12 45.5 0.0 7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Rad17 PF03215.10 CCF53524.1 - 2.3e-46 158.5 0.0 4e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCF53524.1 - 0.0016 18.4 1.4 0.0093 15.9 0.1 2.9 1 1 3 4 4 4 1 AAA ATPase domain AAA_29 PF13555.1 CCF53524.1 - 0.0045 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCF53524.1 - 0.0048 17.0 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCF53524.1 - 0.011 15.2 0.2 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCF53524.1 - 0.012 15.9 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CCF53524.1 - 0.012 15.3 1.1 0.28 10.9 0.4 2.5 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 CCF53524.1 - 0.051 12.6 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 CCF53524.1 - 0.055 14.2 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CCF53524.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IBN_N PF03810.14 CCF53525.1 - 4.2e-14 52.2 0.0 1.8e-13 50.1 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 CCF53525.1 - 5.3e-09 35.1 0.0 2.4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Cse1 HEAT_EZ PF13513.1 CCF53525.1 - 0.00061 20.1 2.4 0.32 11.5 0.0 4.2 3 0 0 3 3 3 1 HEAT-like repeat Xpo1 PF08389.7 CCF53525.1 - 0.0042 16.9 0.2 0.056 13.3 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 CCF53525.1 - 0.0081 16.1 0.9 0.71 10.1 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat Translin PF01997.11 CCF53526.1 - 1.3e-35 122.8 0.1 1.7e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Translin family Tweety PF04906.8 CCF53526.1 - 0.012 14.0 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 Tweety DHC_N2 PF08393.8 CCF53526.1 - 0.021 13.3 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 ATP-synt_D PF01813.12 CCF53526.1 - 0.14 11.6 0.2 8.7 5.8 0.0 2.4 2 1 0 2 2 2 0 ATP synthase subunit D Ribosomal_L1 PF00687.16 CCF53527.1 - 8.1e-52 175.7 0.9 1.1e-51 175.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Motile_Sperm PF00635.21 CCF53528.1 - 2e-25 88.5 0.1 3.4e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF1192 PF06698.6 CCF53528.1 - 0.048 13.4 1.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MSP1_C PF07462.6 CCF53528.1 - 7.7 4.7 6.1 9.2 4.5 4.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4336 PF14234.1 CCF53529.1 - 1.6e-08 34.0 0.0 0.0081 15.3 0.0 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) ATPgrasp_Ter PF15632.1 CCF53530.1 - 0.0016 17.2 0.0 0.0062 15.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon TAT_ubiq PF07706.7 CCF53530.1 - 0.057 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Aminotransferase ubiquitination site DUF3608 PF12257.3 CCF53531.1 - 1.8e-73 246.8 0.0 3.1e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCF53531.1 - 2.2e-20 72.1 0.2 5e-20 71.0 0.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2 PF01569.16 CCF53532.1 - 3.2e-10 39.7 8.0 3.2e-10 39.7 5.5 2.2 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCF53532.1 - 2.8e-06 26.9 12.5 2.8e-06 26.9 8.7 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 CCF53532.1 - 0.26 11.5 10.2 0.064 13.5 4.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF4449 PF14613.1 CCF53533.1 - 8.4e-09 35.5 0.1 8.4e-09 35.5 0.0 3.4 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) Katanin_con80 PF13925.1 CCF53533.1 - 0.019 14.6 0.0 0.07 12.8 0.0 1.9 1 0 0 1 1 1 0 con80 domain of Katanin Holin_LLH PF09682.5 CCF53533.1 - 0.12 12.5 2.6 1.3 9.2 0.1 3.3 3 0 0 3 3 3 0 Phage holin protein (Holin_LLH) HisKA_3 PF07730.8 CCF53533.1 - 0.61 10.4 14.9 2.7 8.3 0.0 6.4 6 2 1 7 7 7 0 Histidine kinase Ribosomal_60s PF00428.14 CCF53533.1 - 0.64 10.4 7.8 0.69 10.3 0.1 3.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF883 PF05957.8 CCF53533.1 - 5.3 7.5 37.2 0.16 12.3 0.3 6.7 4 1 3 7 7 7 0 Bacterial protein of unknown function (DUF883) Sugar_tr PF00083.19 CCF53534.1 - 1.3e-98 330.5 26.3 1.5e-98 330.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53534.1 - 1.2e-17 63.6 44.1 2.3e-12 46.2 9.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 CCF53534.1 - 0.38 10.6 5.7 0.46 10.4 0.6 2.8 2 0 0 2 2 2 0 YtpI-like protein DUF1228 PF06779.9 CCF53534.1 - 2.8 8.0 10.8 0.096 12.7 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) DUF2418 PF10332.4 CCF53536.1 - 3.3e-30 104.2 0.1 8.2e-30 103.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) zf-CCCH PF00642.19 CCF53537.1 - 5.3e-12 45.1 16.6 8.7e-07 28.4 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3512 PF12024.3 CCF53538.1 - 2.2e-05 23.8 1.9 3.1e-05 23.4 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3512) WD40 PF00400.27 CCF53539.1 - 6.5e-25 86.0 3.0 6.7e-06 25.7 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CCF53539.1 - 1.6e-06 28.0 0.1 9.6e-05 22.1 0.1 2.7 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCF53539.1 - 0.00022 20.4 0.1 0.001 18.2 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CCF53539.1 - 0.00065 17.6 0.3 0.24 9.1 0.1 2.6 2 1 1 3 3 3 2 IKI3 family Apc4_WD40 PF12894.2 CCF53539.1 - 0.011 15.2 0.0 8.1 6.0 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MCM PF00493.18 CCF53540.1 - 2.1e-133 444.2 0.0 3e-133 443.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCF53540.1 - 1.2e-19 70.9 0.0 6.6e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CCF53540.1 - 7e-08 32.2 0.0 2.1e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCF53540.1 - 4.9e-07 29.1 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCF53540.1 - 0.00035 20.1 0.1 0.028 14.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF53540.1 - 0.005 16.3 0.2 1.3 8.5 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain DSX_dimer PF08828.5 CCF53540.1 - 0.22 11.0 5.2 9.9 5.7 0.3 3.4 3 0 0 3 3 3 0 Doublesex dimerisation domain DUF605 PF04652.11 CCF53541.1 - 7e-102 341.6 21.2 9.8e-77 258.8 7.5 2.0 1 1 1 2 2 2 2 Vta1 like Ras PF00071.17 CCF53543.1 - 3e-54 182.7 0.0 3.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF53543.1 - 2.4e-20 73.2 0.0 4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF53543.1 - 2.1e-07 30.3 0.0 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF53543.1 - 0.00032 20.1 0.1 0.0026 17.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCF53543.1 - 0.00075 18.7 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF53543.1 - 0.0024 17.8 0.0 0.0062 16.4 0.0 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF53543.1 - 0.018 14.2 0.1 0.11 11.7 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 CCF53543.1 - 0.04 13.2 0.0 0.057 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 CCF53543.1 - 0.13 11.6 0.2 0.31 10.4 0.1 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1762 PF08574.5 CCF53544.1 - 1.4e-05 25.3 6.9 1.4e-05 25.3 4.8 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1762) Rhomboid PF01694.17 CCF53545.1 - 5.8e-30 104.2 12.5 5.8e-30 104.2 8.7 2.2 3 0 0 3 3 3 1 Rhomboid family Intg_mem_TP0381 PF09529.5 CCF53545.1 - 0.048 12.9 0.4 0.098 11.8 0.0 1.7 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) Glyco_hydro_72 PF03198.9 CCF53546.1 - 4.3e-38 131.0 0.0 6.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CCF53546.1 - 1.2e-16 60.9 4.6 1.2e-16 60.9 3.2 1.8 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.10 CCF53547.1 - 0 1367.7 0.0 0 1367.4 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCF53547.1 - 4.6e-37 126.4 0.0 1.1e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 CENP-L PF13092.1 CCF53548.1 - 2.4e-08 33.9 0.0 6.3e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Longin PF13774.1 CCF53549.1 - 8.2e-16 57.3 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCF53549.1 - 2.5e-14 52.6 0.6 4.7e-14 51.7 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin Herpes_teg_N PF04843.7 CCF53549.1 - 0.086 12.2 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region zf-DHHC PF01529.15 CCF53550.1 - 4.4e-41 140.1 6.0 8.3e-41 139.2 4.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 CCF53550.1 - 0.13 12.1 1.9 0.25 11.1 1.3 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ribosomal_S27e PF01667.12 CCF53551.1 - 3.1e-28 97.0 4.5 4.2e-28 96.6 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.4 CCF53551.1 - 0.0045 16.0 0.5 0.12 11.4 0.1 2.1 1 1 1 2 2 2 1 Mu-like prophage protein Com TF_Zn_Ribbon PF08271.7 CCF53551.1 - 0.056 12.7 0.3 0.092 12.0 0.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-CSL PF05207.8 CCF53551.1 - 0.14 11.6 0.7 0.26 10.8 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger zf-LSD1 PF06943.7 CCF53551.1 - 0.17 11.5 1.4 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 LSD1 zinc finger DUF3133 PF11331.3 CCF53551.1 - 0.23 11.0 3.9 3.6 7.2 2.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3133) Ribosomal_L19e PF01280.15 CCF53552.1 - 1.9e-61 206.1 10.3 1.9e-61 206.1 7.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e SGL PF08450.7 CCF53553.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 CCF53553.1 - 0.025 14.6 0.0 0.074 13.1 0.0 1.7 2 0 0 2 2 2 0 Strictosidine synthase Arylesterase PF01731.15 CCF53553.1 - 0.052 13.5 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Arylesterase SR-25 PF10500.4 CCF53553.1 - 3.1 7.1 5.9 5.2 6.4 4.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Salp15 PF12115.3 CCF53554.1 - 0.28 11.4 5.0 0.38 10.9 2.6 2.0 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Destabilase PF05497.7 CCF53554.1 - 2.4 8.2 6.4 0.18 11.8 0.4 2.1 3 0 0 3 3 3 0 Destabilase Sugar_tr PF00083.19 CCF53555.1 - 2.1e-107 359.4 25.0 3e-107 358.9 17.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53555.1 - 2.1e-30 105.6 64.0 7.6e-26 90.6 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Yippee-Mis18 PF03226.9 CCF53557.1 - 4.7e-22 77.8 0.1 5.4e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Evr1_Alr PF04777.8 CCF53557.1 - 0.28 11.0 1.1 0.85 9.5 0.2 1.9 1 1 1 2 2 2 0 Erv1 / Alr family Endonuclease_7 PF02945.10 CCF53557.1 - 0.46 10.2 2.3 1.7 8.4 1.6 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII TIM21 PF08294.6 CCF53558.1 - 5.9e-14 51.9 0.0 4.7e-10 39.2 0.0 2.4 2 1 0 2 2 2 2 TIM21 DPBB_1 PF03330.13 CCF53559.1 - 4e-05 23.5 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SNARE PF05739.14 CCF53560.1 - 1.5e-08 34.1 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 CCF53560.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF1664 PF07889.7 CCF53560.1 - 0.045 13.5 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4316 PF14195.1 CCF53560.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF4234 PF14018.1 CCF53560.1 - 0.14 11.9 2.3 0.21 11.3 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF4349 PF14257.1 CCF53560.1 - 0.15 11.2 0.6 0.2 10.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Citrate_synt PF00285.16 CCF53561.1 - 4.8e-100 334.7 0.0 5.8e-100 334.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 CCF53561.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 XH domain WD40 PF00400.27 CCF53562.1 - 1.4e-10 40.6 1.7 0.76 9.7 0.4 6.4 5 2 0 5 5 5 5 WD domain, G-beta repeat Glyco_transf_41 PF13844.1 CCF53563.1 - 2.2e-101 339.1 2.2 1.2e-47 161.9 0.0 4.1 2 1 2 4 4 4 4 Glycosyl transferase family 41 TPR_11 PF13414.1 CCF53563.1 - 1.2e-23 82.5 4.1 3e-10 39.5 0.0 4.6 4 1 1 5 5 4 4 TPR repeat TPR_1 PF00515.23 CCF53563.1 - 6e-21 73.1 0.0 6.6e-06 25.5 0.0 5.3 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCF53563.1 - 3.5e-16 57.7 0.1 0.00046 19.8 0.0 6.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF53563.1 - 5.7e-16 57.3 11.7 0.0018 18.2 0.0 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCF53563.1 - 1e-14 54.2 2.3 1.6e-06 27.9 0.0 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCF53563.1 - 2.3e-13 49.4 1.0 0.00061 20.2 0.0 6.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCF53563.1 - 4.1e-13 48.0 0.1 4.9e-05 22.8 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCF53563.1 - 1.5e-09 37.4 11.1 0.0048 16.7 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF53563.1 - 4.6e-08 33.2 6.8 0.0003 21.0 0.2 5.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF53563.1 - 1.3e-07 30.8 0.0 0.25 11.2 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF53563.1 - 6.9e-07 29.7 0.0 5.6e-05 23.6 0.0 6.3 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCF53563.1 - 0.00011 21.9 0.3 0.095 12.5 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCF53563.1 - 0.0002 21.5 0.0 1.2 9.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 CCF53564.1 - 9.9e-07 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCF53564.1 - 0.00017 21.3 0.5 0.00031 20.5 0.0 1.6 2 0 0 2 2 2 1 Pam16 T2SF PF00482.18 CCF53564.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Sec23_trunk PF04811.10 CCF53565.1 - 5.4e-78 261.7 0.0 7.7e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCF53565.1 - 1.7e-35 120.5 0.2 3.1e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCF53565.1 - 2.2e-30 105.0 0.0 3.9e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCF53565.1 - 6.6e-17 60.7 6.2 1.2e-16 59.9 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCF53565.1 - 1.2e-11 44.1 0.0 2.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat PIN_4 PF13638.1 CCF53566.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 PIN domain Ribosomal_L28 PF00830.14 CCF53567.1 - 1.1e-23 82.8 0.4 1.7e-23 82.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family DUF3086 PF11285.3 CCF53567.1 - 0.041 12.7 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Brix PF04427.13 CCF53568.1 - 1.2e-45 155.5 0.5 1.5e-45 155.1 0.3 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 CCF53568.1 - 0.096 12.3 0.1 3.1 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) ATP-synt_ab PF00006.20 CCF53569.1 - 2.4e-60 203.6 0.0 3.3e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCF53569.1 - 8.1e-18 64.9 0.1 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCF53569.1 - 4e-12 46.1 0.3 7.4e-12 45.3 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCF53569.1 - 0.00039 20.2 0.2 0.00081 19.2 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF3533 PF12051.3 CCF53569.1 - 0.0048 15.7 0.0 0.0079 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DAO PF01266.19 CCF53570.1 - 3.6e-48 164.2 0.2 5.5e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 CCF53570.1 - 1.2e-08 34.9 2.2 2.2e-08 34.1 1.0 1.8 2 0 0 2 2 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CCF53570.1 - 4.4e-07 29.2 3.6 5.7e-05 22.6 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain FAD_oxidored PF12831.2 CCF53570.1 - 2.7e-06 26.7 0.5 8.8e-06 25.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_8 PF13833.1 CCF53570.1 - 1.3e-05 24.7 2.6 0.00016 21.2 0.8 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CCF53570.1 - 3.3e-05 22.8 1.5 0.016 14.4 0.2 2.7 2 0 0 2 2 2 2 EF hand FAD_binding_3 PF01494.14 CCF53570.1 - 0.00013 21.1 0.1 0.26 10.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain EF-hand_5 PF13202.1 CCF53570.1 - 0.00085 18.5 1.0 0.0022 17.2 0.7 1.7 1 0 0 1 1 1 1 EF hand Pyr_redox_2 PF07992.9 CCF53570.1 - 0.001 18.9 0.2 0.0034 17.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF53570.1 - 0.0011 17.9 4.5 0.0044 15.9 3.1 2.0 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CCF53570.1 - 0.0057 15.5 0.2 0.032 13.1 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCF53570.1 - 0.0069 16.0 0.2 0.02 14.5 0.2 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 CCF53570.1 - 0.036 14.0 0.5 0.15 12.1 0.3 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCF53570.1 - 0.05 14.0 0.9 0.14 12.5 0.6 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF53570.1 - 0.054 13.5 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF53570.1 - 0.1 11.0 1.2 0.19 10.1 0.8 1.4 1 0 0 1 1 1 0 HI0933-like protein RNase_H2-Ydr279 PF09468.5 CCF53571.1 - 0.045 12.9 7.5 0.048 12.8 5.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) N1221 PF07923.8 CCF53571.1 - 0.046 12.5 0.1 0.046 12.5 0.1 1.5 1 1 0 1 1 1 0 N1221-like protein Med5 PF08689.5 CCF53571.1 - 0.28 8.7 3.9 0.32 8.6 2.7 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 DDHD PF02862.12 CCF53571.1 - 4.3 7.0 9.4 5 6.8 6.5 1.1 1 0 0 1 1 1 0 DDHD domain TPR_11 PF13414.1 CCF53572.1 - 1.1e-22 79.4 6.1 3.7e-14 52.1 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCF53572.1 - 1.5e-14 52.9 1.9 2.6e-06 26.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCF53572.1 - 1.2e-12 46.7 9.0 2.2e-05 24.0 0.1 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat RPAP3_C PF13877.1 CCF53572.1 - 6.3e-12 45.3 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 CCF53572.1 - 8.1e-09 35.9 13.9 5.7e-05 23.6 2.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCF53572.1 - 5.2e-08 32.8 4.5 0.00058 20.2 0.8 4.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF53572.1 - 3.6e-07 29.8 3.3 0.35 11.1 0.0 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF53572.1 - 4.7e-07 30.0 6.5 0.016 15.5 0.7 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCF53572.1 - 1.7e-05 24.6 1.0 0.00016 21.4 0.2 2.3 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCF53572.1 - 0.0078 16.0 0.3 1.3 8.9 0.0 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 CCF53572.1 - 0.0085 16.0 1.5 0.038 13.9 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCF53572.1 - 0.012 15.2 0.4 6.2 6.8 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF53572.1 - 0.025 14.3 2.5 2.2 8.2 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF53572.1 - 0.19 12.2 7.7 1.6 9.3 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCF53572.1 - 3 8.0 6.3 3.3 7.8 0.8 3.5 4 1 1 5 5 4 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 CCF53573.1 - 2.3e-37 128.8 0.0 4.1e-37 127.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF53573.1 - 3.5e-05 23.1 0.0 6.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_6 PF12697.2 CCF53573.1 - 0.55 10.0 9.1 0.57 10.0 3.9 2.6 1 1 1 3 3 3 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 CCF53575.1 - 3.9e-17 62.0 0.1 6.1e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCF53575.1 - 7.5e-10 38.4 0.1 1.2e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCF53575.1 - 7.2e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCF53575.1 - 1.3e-08 34.9 0.1 4.2e-08 33.3 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCF53575.1 - 1.2e-06 28.7 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF53575.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF53575.1 - 1.9e-05 24.5 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCF53575.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 CCF53575.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PCI PF01399.22 CCF53577.1 - 6.9e-05 23.1 0.0 0.00016 21.9 0.0 1.7 1 1 0 1 1 1 1 PCI domain Pollen_Ole_e_I PF01190.12 CCF53580.1 - 0.025 14.4 0.1 0.039 13.7 0.0 1.3 1 1 0 1 1 1 0 Pollen proteins Ole e I like KilA-N PF04383.8 CCF53581.1 - 0.0009 18.8 0.0 0.0019 17.8 0.0 1.5 1 1 0 1 1 1 1 KilA-N domain Pkinase PF00069.20 CCF53582.1 - 6.2e-68 228.7 0.0 9.5e-68 228.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53582.1 - 3.6e-46 157.3 0.0 5.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF53582.1 - 1.7e-08 33.7 0.0 4e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCF53582.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras_bdg_2 PF14847.1 CCF53582.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Seadorna_VP7 PF07387.6 CCF53582.1 - 1.8 7.3 0.0 2.8 6.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 LIM PF00412.17 CCF53583.1 - 9.4e-13 48.0 42.1 8.6e-11 41.7 2.3 4.6 5 0 0 5 5 5 3 LIM domain MCM PF00493.18 CCF53584.1 - 3.7e-139 463.1 0.1 6.7e-139 462.2 0.1 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCF53584.1 - 6.5e-32 110.6 25.8 6.5e-32 110.6 17.9 3.0 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCF53584.1 - 2.4e-18 66.7 0.0 5.4e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCF53584.1 - 1.4e-08 34.2 0.0 3.7e-07 29.5 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCF53584.1 - 1.7e-06 27.8 0.0 4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCF53584.1 - 1.8e-05 24.3 0.2 0.00031 20.3 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF53584.1 - 0.0079 15.6 0.1 0.066 12.6 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CCF53584.1 - 0.07 13.3 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) polyprenyl_synt PF00348.12 CCF53585.1 - 7.7e-74 247.8 0.0 1e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Dynactin_p62 PF05502.8 CCF53586.1 - 1.9e-129 432.5 4.2 2.8e-129 432.0 2.9 1.3 1 0 0 1 1 1 1 Dynactin p62 family Pkinase PF00069.20 CCF53588.1 - 1.5e-52 178.3 0.0 1.3e-46 158.8 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53588.1 - 1.6e-25 89.6 0.8 6.5e-21 74.5 0.0 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.1 CCF53588.1 - 0.00013 21.0 0.0 0.31 9.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like XAP5 PF04921.9 CCF53588.1 - 0.0088 15.6 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator Seadorna_VP7 PF07387.6 CCF53588.1 - 0.32 9.7 0.0 0.52 9.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cyto_heme_lyase PF01265.12 CCF53589.1 - 2.4e-69 233.8 4.7 1.6e-68 231.1 3.2 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SR-25 PF10500.4 CCF53589.1 - 0.31 10.4 24.0 0.59 9.5 3.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3827 PF12877.2 CCF53589.1 - 2 6.4 6.3 3 5.8 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TFIIA PF03153.8 CCF53589.1 - 8.6 6.1 13.7 12 5.6 9.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF607 PF04678.8 CCF53590.1 - 3.4e-42 144.3 0.0 7.5e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF607 UbiA PF01040.13 CCF53590.1 - 1.7e-29 102.8 18.3 1.7e-29 102.8 12.7 2.1 2 0 0 2 2 2 1 UbiA prenyltransferase family Brr6_like_C_C PF10104.4 CCF53592.1 - 5.1e-42 142.5 0.3 6.8e-42 142.1 0.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CENP-B_dimeris PF09026.5 CCF53592.1 - 0.047 13.9 2.0 0.089 13.0 1.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 CCF53592.1 - 0.055 11.3 0.1 0.11 10.3 0.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 CCF53592.1 - 0.063 12.8 1.5 0.095 12.2 1.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Oxidored_q2 PF00420.19 CCF53592.1 - 0.096 12.2 0.0 9.2 5.9 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ctr PF04145.10 CCF53592.1 - 0.14 12.1 0.6 1 9.3 0.0 2.5 3 0 0 3 3 3 0 Ctr copper transporter family Y_phosphatase2 PF03162.8 CCF53593.1 - 4.6e-24 84.6 0.0 5.6e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCF53593.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Nop14 PF04147.7 CCF53593.1 - 0.55 8.0 47.7 0.93 7.3 33.1 1.4 1 0 0 1 1 1 0 Nop14-like family AIP3 PF03915.8 CCF53594.1 - 3e-109 365.7 0.3 3e-109 365.7 0.2 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 DUF2315 PF10231.4 CCF53594.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) DUF383 PF04063.9 CCF53595.1 - 1.4e-74 249.8 0.2 3.3e-74 248.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCF53595.1 - 8.2e-19 66.9 0.1 1.6e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Cnd1 PF12717.2 CCF53595.1 - 0.034 13.9 0.3 40 3.9 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCF53595.1 - 0.097 12.8 4.1 0.2 11.7 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Zn_clus PF00172.13 CCF53596.1 - 4.3e-09 36.1 10.2 8.5e-09 35.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 CCF53596.1 - 1.2 7.8 11.0 1.8 7.2 7.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HMG_box PF00505.14 CCF53597.1 - 6.5e-11 42.3 3.1 6.5e-11 42.3 2.1 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box DNA_pol_B PF00136.16 CCF53598.1 - 8.1e-147 489.7 2.0 1.2e-146 489.1 1.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCF53598.1 - 1.3e-91 306.8 0.0 2.3e-91 306.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCF53598.1 - 4.2e-23 81.1 7.4 9.5e-23 79.9 5.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CCF53598.1 - 0.0023 16.6 2.1 0.0047 15.6 0.2 2.4 2 1 1 3 3 3 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 CCF53598.1 - 0.018 14.8 0.2 0.063 13.0 0.1 2.1 1 1 0 1 1 1 0 RNase_H superfamily zf-RING-like PF08746.6 CCF53598.1 - 1.5 8.9 8.1 0.056 13.4 0.7 2.4 2 0 0 2 2 2 0 RING-like domain AMP-binding PF00501.23 CCF53599.1 - 5.5e-82 275.3 0.0 8.2e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF53599.1 - 1.2e-11 45.3 0.2 2.9e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 CCF53599.1 - 0.0018 16.8 0.1 0.24 9.9 0.0 2.1 2 0 0 2 2 2 2 GH3 auxin-responsive promoter Nol1_Nop2_Fmu PF01189.12 CCF53600.1 - 3e-96 322.1 0.0 4.4e-96 321.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CCF53600.1 - 6.9e-05 22.4 0.0 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CCF53600.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 CCF53600.1 - 0.0019 18.2 0.4 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 CCF53600.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CCF53600.1 - 0.037 14.5 0.2 0.18 12.3 0.0 2.4 3 1 0 3 3 3 0 Methyltransferase domain Sigma70_ner PF04546.8 CCF53600.1 - 0.1 12.2 31.0 0.012 15.2 3.5 3.5 3 0 0 3 3 3 0 Sigma-70, non-essential region Acyl-CoA_dh_1 PF00441.19 CCF53601.1 - 2.4e-31 108.8 0.3 3.9e-31 108.1 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF53601.1 - 8.9e-17 60.3 0.8 2.4e-16 58.9 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 CCF53601.1 - 4.1e-16 58.5 0.0 8.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 CCF53601.1 - 1.3e-12 48.3 0.0 7e-12 45.9 0.0 2.3 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CCF53601.1 - 2.9e-06 27.5 0.0 7.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CCF53601.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PXA PF02194.10 CCF53603.1 - 9.3e-21 74.2 0.7 6e-20 71.5 0.5 2.4 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.7 CCF53603.1 - 3.4e-09 36.7 0.0 1.1e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.4 CCF53603.1 - 0.4 10.3 2.5 0.71 9.5 1.8 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) EIF_2_alpha PF07541.7 CCF53604.1 - 1.5e-40 137.4 0.3 3.5e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCF53604.1 - 2.4e-13 49.9 1.0 5.2e-13 48.8 0.3 2.0 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.4 CCF53604.1 - 0.025 14.5 0.1 0.067 13.1 0.1 2.0 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 DUF4453 PF14627.1 CCF53604.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) Ank_2 PF12796.2 CCF53605.1 - 5.2e-06 26.7 0.0 0.00021 21.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCF53605.1 - 0.00024 20.7 0.3 0.29 11.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCF53605.1 - 0.0014 19.0 0.3 0.0046 17.4 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF53605.1 - 0.013 15.6 0.1 4.6 7.7 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat CDC45 PF02724.9 CCF53605.1 - 2.2 6.1 6.9 2.1 6.2 3.3 1.8 2 0 0 2 2 2 0 CDC45-like protein Trehalase PF01204.13 CCF53606.1 - 2.4e-171 570.8 0.0 3.1e-171 570.4 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCF53606.1 - 3.9e-14 51.6 0.1 7.5e-14 50.7 0.1 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Carn_acyltransf PF00755.15 CCF53607.1 - 3.5e-139 464.6 0.0 5.8e-139 463.8 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase tRNA-synt_1d PF00750.14 CCF53608.1 - 2.8e-86 289.5 2.1 3.6e-86 289.1 1.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCF53608.1 - 5.5e-22 77.9 1.3 4.8e-21 74.9 0.0 2.8 3 0 0 3 3 3 1 DALR anticodon binding domain DivIC PF04977.10 CCF53609.1 - 0.87 9.1 14.3 2.1 7.9 1.0 3.8 1 1 2 3 3 3 0 Septum formation initiator DUF2454 PF10521.4 CCF53610.1 - 5.2e-14 51.9 0.1 4.9e-11 42.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) CPSF73-100_C PF11718.3 CCF53612.1 - 3.6e-45 153.9 7.0 3.3e-44 150.8 4.1 2.4 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCF53612.1 - 4.1e-30 104.3 0.0 9.3e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CCF53612.1 - 1.4e-17 63.9 2.5 1.4e-17 63.9 1.7 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCF53612.1 - 9.8e-12 44.8 3.2 9.8e-12 44.8 2.2 2.7 3 0 0 3 3 3 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CCF53612.1 - 8.4e-11 41.5 0.1 1.5e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CCF53612.1 - 9.9e-08 31.8 2.9 2.1e-07 30.8 0.1 2.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RabGAP-TBC PF00566.13 CCF53613.1 - 5.2e-52 176.4 0.0 7.9e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Phe_ZIP PF08916.6 CCF53613.1 - 0.12 12.7 0.7 3.8 7.9 0.3 2.6 2 0 0 2 2 2 0 Phenylalanine zipper GST_N_2 PF13409.1 CCF53614.1 - 1.1e-15 57.3 0.0 2.4e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF53614.1 - 1.1e-12 47.7 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF53614.1 - 1.8e-06 27.8 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 CCF53615.1 - 0.041 13.6 0.2 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like Spc97_Spc98 PF04130.8 CCF53616.1 - 6.4e-110 368.0 0.0 7.7e-110 367.7 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF148 PF02520.12 CCF53616.1 - 0.079 12.7 0.2 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 DEK_C PF08766.6 CCF53617.1 - 7.5e-06 25.6 0.4 2.6e-05 23.9 0.2 2.0 1 1 0 1 1 1 1 DEK C terminal domain MIP-T3 PF10243.4 CCF53617.1 - 0.24 9.8 38.4 0.37 9.1 26.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IFT57 PF10498.4 CCF53617.1 - 4.9 5.7 25.4 0.011 14.5 4.3 2.5 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Sugar_tr PF00083.19 CCF53618.1 - 2.8e-95 319.5 22.3 3.3e-95 319.3 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53618.1 - 2.8e-22 78.9 26.8 2e-19 69.5 11.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCF53619.1 - 7.6e-29 98.5 12.3 1.9e-06 27.5 0.0 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CCF53619.1 - 1.4e-06 27.9 1.9 9e-06 25.3 0.9 2.2 1 1 1 2 2 2 1 PQQ-like domain LysM PF01476.15 CCF53619.1 - 0.036 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 LysM domain PQQ_3 PF13570.1 CCF53619.1 - 0.38 11.1 10.3 10 6.5 0.0 4.9 5 0 0 5 5 5 0 PQQ-like domain DZR PF12773.2 CCF53619.1 - 3.5 7.5 8.5 8.7 6.2 5.9 1.7 1 0 0 1 1 1 0 Double zinc ribbon LRR_4 PF12799.2 CCF53620.1 - 3e-46 154.3 43.7 1.7e-10 40.2 2.6 6.7 2 2 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF53620.1 - 1.5e-26 91.8 58.9 9.1e-08 31.7 4.1 5.3 3 2 4 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 CCF53620.1 - 2.7e-14 51.5 15.6 0.045 13.8 0.2 9.7 8 1 2 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 CCF53620.1 - 7.7e-14 49.6 26.8 0.082 12.9 0.6 10.2 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.1 CCF53620.1 - 9.2e-12 44.8 6.8 2.1e-06 27.4 0.6 3.7 1 1 2 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 CCF53620.1 - 3.5e-10 38.3 24.0 0.52 10.7 0.1 9.3 9 0 0 9 9 9 3 Leucine rich repeat BESS PF02944.15 CCF53620.1 - 0.042 13.4 0.1 0.099 12.2 0.1 1.6 1 0 0 1 1 1 0 BESS motif Daxx PF03344.10 CCF53620.1 - 0.77 8.1 6.0 1.1 7.7 4.1 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 CCF53620.1 - 3.2 6.5 7.8 4 6.2 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) FA_hydroxylase PF04116.8 CCF53621.1 - 1.2e-14 54.6 17.9 1.2e-14 54.6 12.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RHH_3 PF12651.2 CCF53621.1 - 0.091 12.5 0.2 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain Peptidase_M16 PF00675.15 CCF53622.1 - 3.8e-21 75.4 0.2 6.7e-20 71.3 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCF53622.1 - 3.2e-14 53.0 0.1 1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Sad1_UNC PF07738.8 CCF53623.1 - 0.0029 17.3 0.1 0.52 10.1 0.0 2.7 2 1 1 3 3 3 1 Sad1 / UNC-like C-terminal HALZ PF02183.13 CCF53623.1 - 0.0098 15.5 1.3 0.037 13.7 0.3 2.4 3 0 0 3 3 3 1 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 CCF53623.1 - 0.075 12.8 5.3 0.41 10.4 1.1 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 CCF53623.1 - 0.14 11.1 6.1 0.44 9.5 4.1 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.1 CCF53623.1 - 3.5 6.5 12.9 1.8 7.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.6 CCF53623.1 - 3.6 5.0 6.3 5.8 4.3 4.3 1.2 1 0 0 1 1 1 0 Prominin DUF342 PF03961.8 CCF53623.1 - 6.6 5.0 6.6 0.31 9.4 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ATP_bind_1 PF03029.12 CCF53624.1 - 5.9e-76 255.1 0.6 3.5e-69 232.9 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CCF53624.1 - 5.5e-08 32.4 1.1 3.5e-07 29.8 0.7 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 CCF53624.1 - 4.6e-06 26.1 0.9 0.00051 19.4 0.1 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 CCF53624.1 - 0.00015 21.7 0.3 0.00094 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCF53624.1 - 0.00024 21.0 0.0 0.0012 18.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CCF53624.1 - 0.001 19.8 0.2 0.0058 17.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCF53624.1 - 0.0014 18.7 0.0 0.0048 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCF53624.1 - 0.0015 18.4 5.0 0.0019 18.0 0.4 3.0 3 1 0 3 3 2 1 AAA domain FeoB_N PF02421.13 CCF53624.1 - 0.0016 17.7 0.0 0.006 15.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_25 PF13481.1 CCF53624.1 - 0.0017 17.8 0.0 0.29 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain FbpA PF05833.6 CCF53624.1 - 0.0019 16.8 0.2 0.0019 16.8 0.2 1.5 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) AAA_10 PF12846.2 CCF53624.1 - 0.0022 17.4 0.4 0.29 10.5 0.0 2.2 2 1 0 2 2 2 1 AAA-like domain Septin PF00735.13 CCF53624.1 - 0.0031 16.5 0.0 0.0064 15.5 0.0 1.5 1 0 0 1 1 1 1 Septin ArgK PF03308.11 CCF53624.1 - 0.0076 15.0 0.4 0.32 9.7 0.0 2.4 2 1 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 CCF53624.1 - 0.008 16.4 0.8 0.019 15.2 0.0 2.0 3 0 0 3 3 1 1 AAA domain NACHT PF05729.7 CCF53624.1 - 0.0094 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.17 CCF53624.1 - 0.011 15.2 0.1 0.22 10.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 CCF53624.1 - 0.014 15.6 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CCF53624.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CCF53624.1 - 0.029 14.0 0.1 4 7.1 0.0 2.6 3 0 0 3 3 3 0 NTPase Miro PF08477.8 CCF53624.1 - 0.036 14.5 0.5 1 9.8 0.1 2.5 2 0 0 2 2 2 0 Miro-like protein DUF2962 PF11176.3 CCF53624.1 - 0.038 13.5 2.5 0.095 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) G-alpha PF00503.15 CCF53624.1 - 0.054 12.1 3.8 0.34 9.5 0.2 2.5 3 0 0 3 3 3 0 G-protein alpha subunit T2SE PF00437.15 CCF53624.1 - 0.056 12.3 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 CCF53624.1 - 0.058 12.5 0.1 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 CCF53624.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 CCF53624.1 - 0.094 12.5 3.5 0.1 12.3 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function DUF87 DUF258 PF03193.11 CCF53624.1 - 0.11 11.7 0.4 0.51 9.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 CCF53624.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CCF53624.1 - 0.17 11.3 0.7 1 8.8 0.1 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3987 PF13148.1 CCF53624.1 - 0.56 8.7 4.9 3.3 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APC_CDC26 PF10471.4 CCF53624.1 - 0.75 10.5 9.7 0.29 11.9 2.3 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Thymidylate_kin PF02223.12 CCF53624.1 - 0.82 9.0 3.5 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase U1snRNP70_N PF12220.3 CCF53624.1 - 1.2 9.4 6.6 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Zn_clus PF00172.13 CCF53625.1 - 1.6e-06 27.9 9.5 2.9e-06 27.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UMP1 PF05348.6 CCF53626.1 - 4.3e-22 78.4 0.4 5.4e-22 78.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 rRNA_proc-arch PF13234.1 CCF53627.1 - 1.6e-92 309.5 0.0 2.3e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CCF53627.1 - 6.8e-59 198.1 2.3 9.1e-59 197.7 0.2 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CCF53627.1 - 1.1e-21 77.0 0.0 6.4e-21 74.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF53627.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCF53627.1 - 0.054 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 CCF53627.1 - 0.095 12.5 0.0 1.2 8.9 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TLP-20 PF06088.6 CCF53627.1 - 2.6 7.6 7.6 7.2 6.2 5.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) 5_nucleotid_C PF02872.13 CCF53628.1 - 3.8e-26 91.9 0.0 1.3e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CCF53628.1 - 5.5e-09 35.7 1.3 3.8e-08 32.9 0.9 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Med9 PF07544.8 CCF53628.1 - 7.5e-06 25.5 0.4 3.4e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Metallophos_2 PF12850.2 CCF53628.1 - 0.005 16.6 0.0 0.022 14.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Syntaxin-6_N PF09177.6 CCF53629.1 - 4.2e-21 75.1 2.4 6.4e-21 74.5 0.1 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 CCF53629.1 - 1.6e-11 43.6 3.5 1.6e-11 43.6 2.5 2.3 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.11 CCF53629.1 - 0.00021 21.3 3.9 1.7 8.7 0.5 3.2 2 1 1 3 3 3 2 Flagellar FliJ protein DUF3584 PF12128.3 CCF53629.1 - 0.0036 14.7 4.0 0.0043 14.4 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF2959 PF11172.3 CCF53629.1 - 0.0041 16.8 2.9 0.21 11.3 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2959) IFT57 PF10498.4 CCF53629.1 - 0.005 15.6 1.2 0.11 11.2 0.0 2.2 1 1 0 2 2 2 1 Intra-flagellar transport protein 57 Use1 PF09753.4 CCF53629.1 - 0.0091 15.4 2.4 0.08 12.3 1.7 2.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 AAA_13 PF13166.1 CCF53629.1 - 0.026 13.0 3.1 0.17 10.2 2.1 2.0 1 1 0 1 1 1 0 AAA domain HisKA_3 PF07730.8 CCF53629.1 - 0.03 14.6 1.6 9.2 6.6 0.1 2.8 2 1 0 2 2 2 0 Histidine kinase Spectrin PF00435.16 CCF53629.1 - 0.03 14.5 1.1 8.6 6.7 0.0 3.3 2 1 1 3 3 3 0 Spectrin repeat FlxA PF14282.1 CCF53629.1 - 0.042 13.8 0.6 0.042 13.8 0.4 3.0 1 1 0 2 2 2 0 FlxA-like protein FlaC_arch PF05377.6 CCF53629.1 - 0.19 11.6 1.8 3.8 7.4 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF883 PF05957.8 CCF53629.1 - 0.2 12.0 2.4 1.4 9.3 0.2 2.9 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HalX PF08663.5 CCF53629.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.4 3 0 0 3 3 2 0 HalX domain DUF241 PF03087.9 CCF53629.1 - 0.24 10.8 3.3 0.42 10.0 0.6 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF745 PF05335.8 CCF53629.1 - 0.25 10.8 2.3 4.8 6.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.7 CCF53629.1 - 0.47 10.2 4.6 5.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.4 CCF53629.1 - 0.85 7.8 4.9 0.29 9.3 0.3 1.8 1 1 1 2 2 2 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CCF53629.1 - 0.93 9.1 4.4 1.3 8.7 3.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nup88 PF10168.4 CCF53629.1 - 1 7.1 4.1 5.2 4.7 2.9 1.9 1 1 0 1 1 1 0 Nuclear pore component TMF_TATA_bd PF12325.3 CCF53629.1 - 1 9.0 8.3 11 5.7 0.1 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PPTA PF01239.17 CCF53632.1 - 1.8e-34 115.5 11.5 1.7e-08 33.4 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 CCF53632.1 - 0.022 14.9 0.9 1.3 9.4 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCF53632.1 - 0.035 13.7 0.2 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 TPR repeat FliG_M PF14841.1 CCF53632.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 FliG middle domain TPR_19 PF14559.1 CCF53632.1 - 0.11 12.8 0.1 5.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat BolA PF01722.13 CCF53633.1 - 1.1e-24 86.1 0.5 1.1e-24 86.1 0.3 1.7 2 0 0 2 2 2 1 BolA-like protein Ribosomal_L9_N PF01281.14 CCF53633.1 - 9.7e-13 47.1 0.0 1.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain polyprenyl_synt PF00348.12 CCF53634.1 - 1e-39 135.9 0.5 3.9e-20 71.7 0.0 4.1 3 1 0 3 3 3 3 Polyprenyl synthetase RAP1 PF07218.6 CCF53634.1 - 1.1 7.3 12.7 1.7 6.6 8.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF718 PF05336.8 CCF53635.1 - 1e-11 44.5 0.0 1.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Pkinase PF00069.20 CCF53636.1 - 3e-60 203.5 0.0 5.2e-39 133.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53636.1 - 9.9e-26 90.3 0.0 2.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CCF53636.1 - 3.4e-08 33.4 0.1 7.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CCF53636.1 - 2.4e-07 30.0 0.3 9.5e-06 24.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like PAS_9 PF13426.1 CCF53636.1 - 0.0014 18.9 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 CCF53636.1 - 0.015 14.3 0.0 0.043 12.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_3 PF08447.6 CCF53636.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 CCF53636.1 - 0.1 11.4 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Herpes_UL6 PF01763.11 CCF53636.1 - 6.6 4.7 2.5 3 5.9 0.1 1.5 2 0 0 2 2 2 0 Herpesvirus UL6 like Gly_transf_sug PF04488.10 CCF53637.1 - 7e-19 68.1 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCF53637.1 - 0.0082 14.6 1.4 0.11 11.0 0.2 2.5 3 0 0 3 3 3 1 TcdA/TcdB catalytic glycosyltransferase domain Mito_carr PF00153.22 CCF53638.1 - 1.2e-75 249.3 0.0 4.4e-26 90.4 0.0 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Amidase PF01425.16 CCF53639.1 - 9.2e-96 321.3 0.0 1.3e-95 320.8 0.0 1.2 1 0 0 1 1 1 1 Amidase ERG4_ERG24 PF01222.12 CCF53640.1 - 2.8e-124 414.9 21.7 3.2e-124 414.7 15.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ProSAAS PF07259.7 CCF53641.1 - 0.014 14.9 1.5 0.014 14.9 1.0 2.1 1 1 1 2 2 2 0 ProSAAS precursor Ribosomal_L29e PF01779.12 CCF53642.1 - 2.6e-22 78.3 6.5 3.7e-22 77.8 4.5 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family PHD PF00628.24 CCF53643.1 - 1.2e-12 47.2 16.6 1.5e-07 30.9 1.9 3.9 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H PF13771.1 CCF53643.1 - 0.83 9.8 5.5 0.45 10.7 1.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 CCF53643.1 - 1.9 7.7 5.2 3.5 6.8 1.1 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Vps51 PF08700.6 CCF53644.1 - 1.4e-15 56.8 0.4 9.4e-15 54.2 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Pro_isomerase PF00160.16 CCF53645.1 - 9.3e-49 165.6 0.0 1e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Histone PF00125.19 CCF53646.1 - 7.3e-26 90.0 0.0 9.2e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCF53646.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF53647.1 - 1.4e-22 79.6 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCF53647.1 - 3e-06 27.1 0.1 3e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCF53647.1 - 0.00032 20.8 0.0 0.00053 20.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 CCF53647.1 - 0.022 14.2 0.1 0.039 13.4 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 CCF53647.1 - 0.03 14.8 0.4 0.038 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 CCF53647.1 - 0.077 12.3 0.1 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Snf7 PF03357.16 CCF53648.1 - 1.8e-29 102.2 21.0 1.8e-29 102.2 14.5 1.3 1 1 0 1 1 1 1 Snf7 Eno-Rase_FAD_bd PF07055.7 CCF53648.1 - 0.013 15.3 1.6 0.024 14.5 0.1 2.2 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain ACT_5 PF13710.1 CCF53648.1 - 0.028 14.2 1.6 0.11 12.3 0.1 2.4 2 0 0 2 2 2 0 ACT domain Occludin_ELL PF07303.8 CCF53648.1 - 9.1 7.0 10.6 0.99 10.1 3.5 2.2 2 2 1 3 3 3 0 Occludin homology domain MIP PF00230.15 CCF53650.1 - 9e-48 162.6 5.1 1.1e-47 162.4 3.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein PPI_Ypi1 PF07491.6 CCF53651.1 - 1.8e-25 88.3 0.2 1.8e-25 88.3 0.1 2.2 3 0 0 3 3 3 1 Protein phosphatase inhibitor Zip PF02535.17 CCF53651.1 - 0.008 15.2 7.9 0.0089 15.0 5.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.20 CCF53652.1 - 2.3e-26 92.5 0.0 7.7e-26 90.7 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53652.1 - 7.2e-13 48.1 0.0 5e-12 45.4 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Cnd1 PF12717.2 CCF53652.1 - 0.037 13.8 0.4 0.073 12.9 0.3 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 CCF53652.1 - 0.047 12.6 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RING_2 PF13639.1 CCF53653.1 - 2.6e-05 23.9 5.0 5.5e-05 22.9 3.5 1.6 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.12 CCF53653.1 - 0.00035 19.9 1.2 0.00065 19.1 0.9 1.4 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 CCF53653.1 - 0.0024 17.9 0.6 0.0052 16.8 0.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCF53653.1 - 0.0041 17.0 2.9 0.0082 16.0 2.0 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 CCF53653.1 - 0.0096 15.6 2.8 0.019 14.7 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCF53653.1 - 0.058 13.2 4.9 0.17 11.7 3.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CCF53653.1 - 0.11 12.5 5.3 0.24 11.4 3.7 1.6 1 0 0 1 1 1 0 RING-variant domain TPR_MLP1_2 PF07926.7 CCF53654.1 - 0.068 12.9 5.9 0.64 9.7 4.0 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.8 CCF53654.1 - 0.89 9.8 11.5 1.6 9.0 1.8 2.6 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4407 PF14362.1 CCF53654.1 - 3.2 6.6 10.9 7.2 5.4 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UDP-g_GGTase PF06427.6 CCF53656.1 - 2.1e-55 187.3 0.0 3.8e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CCF53656.1 - 1.7e-08 34.1 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 DPBB_1 PF03330.13 CCF53658.1 - 4.2e-10 39.4 0.1 4.2e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 CCF53659.1 - 9e-64 215.1 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53659.1 - 4.7e-36 124.1 0.0 3.2e-34 118.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF53659.1 - 0.00022 20.2 0.0 0.0014 17.6 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.6 CCF53659.1 - 0.046 12.5 0.1 0.094 11.5 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CCF53659.1 - 0.13 12.0 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family GST_N_2 PF13409.1 CCF53660.1 - 1.8e-20 72.6 0.0 3.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCF53660.1 - 7.6e-14 51.3 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF53660.1 - 0.0033 17.3 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCF53660.1 - 0.0061 16.7 0.2 0.041 14.1 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCF53660.1 - 0.011 16.1 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RasGEF PF00617.14 CCF53661.1 - 8.2e-53 178.9 0.0 1.6e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCF53661.1 - 2.1e-25 88.8 0.0 2.1e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_2 PF07653.12 CCF53661.1 - 1.9e-14 52.8 0.1 4.6e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCF53661.1 - 1.1e-13 50.5 0.1 2.1e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCF53661.1 - 6.1e-13 47.9 0.1 1.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF4557 PF15101.1 CCF53661.1 - 8.2 6.2 18.4 22 4.8 11.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) 2-oxoacid_dh PF00198.18 CCF53662.1 - 7.5e-78 260.9 0.2 1e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCF53662.1 - 2.6e-20 71.8 1.5 4.9e-20 70.9 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCF53662.1 - 5.8e-06 25.8 0.2 0.002 17.7 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 CCF53662.1 - 0.00028 21.1 0.1 0.62 10.4 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 CCF53662.1 - 0.0017 18.0 0.4 0.0037 16.9 0.3 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein MIP-T3 PF10243.4 CCF53662.1 - 0.0041 15.6 28.4 0.0068 14.9 19.7 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ribosomal_60s PF00428.14 CCF53662.1 - 0.0056 17.0 2.0 0.0056 17.0 1.4 3.8 2 1 2 4 4 4 1 60s Acidic ribosomal protein DUF605 PF04652.11 CCF53662.1 - 0.28 10.5 26.1 0.36 10.1 18.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF2413 PF10310.4 CCF53662.1 - 3.2 6.4 23.5 5.4 5.7 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Plasmodium_Vir PF05795.6 CCF53662.1 - 7.7 5.6 11.6 12 5.0 8.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF948 PF06103.6 CCF53664.1 - 0.21 11.4 0.1 0.68 9.8 0.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fork_head PF00250.13 CCF53666.1 - 2.1e-19 69.3 0.0 3.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Amidohydro_2 PF04909.9 CCF53667.1 - 1.7e-07 31.0 0.0 4.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CCF53667.1 - 6.9e-07 29.5 0.2 2.1e-06 27.9 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase FUN14 PF04930.10 CCF53668.1 - 1.2e-22 80.0 1.1 5.1e-22 78.0 0.2 2.0 2 0 0 2 2 2 1 FUN14 family LSM PF01423.17 CCF53669.1 - 8.9e-16 57.2 0.0 1.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain HTH_psq PF05225.11 CCF53670.1 - 1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain PRELI PF04707.9 CCF53671.1 - 1.9e-14 53.5 1.0 9.4e-05 22.0 0.0 4.2 4 0 0 4 4 4 4 PRELI-like family Bromodomain PF00439.20 CCF53672.1 - 1.2e-15 57.2 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain MFS_1 PF07690.11 CCF53673.1 - 1.2e-21 76.8 9.4 2e-21 76.1 6.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4149 PF13664.1 CCF53673.1 - 6.7 6.8 10.2 3.7 7.6 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) TFIID_30kDa PF03540.8 CCF53674.1 - 2.1e-26 91.4 0.0 4.2e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 CCF53674.1 - 2.8e-06 27.0 0.0 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2360 PF10152.4 CCF53674.1 - 0.0017 18.6 0.8 0.003 17.8 0.6 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Med3 PF11593.3 CCF53674.1 - 0.74 8.9 9.2 1.4 8.0 6.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA-synt_2d PF01409.15 CCF53676.1 - 8e-88 293.7 0.0 1.1e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCF53676.1 - 2.6e-06 27.1 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CCF53676.1 - 2.8e-05 23.0 0.1 0.00066 18.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) IBN_N PF03810.14 CCF53677.1 - 1.8e-10 40.5 2.7 1.6e-07 31.1 0.2 4.5 4 1 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCF53677.1 - 0.008 16.0 2.0 0.032 14.1 0.1 3.0 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 CCF53677.1 - 0.011 15.9 6.8 0.15 12.3 0.2 4.2 4 0 0 4 4 4 0 HEAT repeats Fanconi_A PF03511.9 CCF53677.1 - 4 7.3 6.5 0.6 9.9 0.2 3.0 3 0 0 3 3 3 0 Fanconi anaemia group A protein Acetyltransf_1 PF00583.19 CCF53678.1 - 2.5e-12 46.6 0.0 5.2e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCF53678.1 - 3e-05 24.1 0.0 4.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCF53678.1 - 0.00021 21.4 0.0 0.00034 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF53678.1 - 0.018 14.7 0.0 0.12 12.1 0.0 2.0 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.1 CCF53678.1 - 0.025 14.4 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Alpha_E3_glycop PF01563.11 CCF53678.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein DUF410 PF04190.8 CCF53682.1 - 1.7e-26 93.3 0.2 1.6e-21 77.0 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_7 PF13176.1 CCF53682.1 - 0.09 12.6 0.4 2 8.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PROCN PF08083.6 CCF53683.1 - 1.4e-192 639.6 3.4 2.1e-192 639.0 2.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCF53683.1 - 2.5e-122 406.5 0.4 4.1e-122 405.8 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCF53683.1 - 1.6e-85 284.3 0.5 4.8e-85 282.8 0.3 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCF53683.1 - 1.3e-77 258.6 3.5 3.1e-77 257.4 2.4 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCF53683.1 - 7.9e-60 200.3 0.0 1.6e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CCF53683.1 - 6.1e-44 147.8 0.5 1.4e-43 146.6 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CCF53683.1 - 4.4e-31 107.1 0.0 9e-31 106.1 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CCF53683.1 - 0.042 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC_CDC26 PF10471.4 CCF53685.1 - 0.013 16.2 11.1 0.24 12.1 7.7 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Hemerythrin PF01814.18 CCF53686.1 - 0.44 10.7 4.0 3.8 7.6 0.3 2.6 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain XhlA PF10779.4 CCF53686.1 - 0.48 10.3 2.1 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Pyr_redox_3 PF13738.1 CCF53687.1 - 6.6e-17 62.2 0.0 4.5e-11 43.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 CCF53687.1 - 5.6e-13 47.9 0.3 3.9e-09 35.2 0.0 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 CCF53687.1 - 2.2e-11 43.2 0.4 1.4e-06 27.4 0.1 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 CCF53687.1 - 6.2e-07 29.4 0.0 0.0001 22.2 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF53687.1 - 1.2e-05 25.1 3.9 0.016 14.9 1.1 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 CCF53687.1 - 0.084 13.2 0.1 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF53687.1 - 2.7 6.8 4.9 0.78 8.5 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase VPEP PF07589.6 CCF53688.1 - 3.7 7.5 6.5 29 4.7 1.2 3.0 2 0 0 2 2 2 0 PEP-CTERM motif RVT_1 PF00078.22 CCF53689.1 - 1.2e-07 31.3 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) JAB PF01398.16 CCF53690.1 - 7.9e-34 115.8 0.0 1.6e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCF53690.1 - 4.3e-28 97.7 3.3 4.3e-28 97.7 2.3 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CCF53690.1 - 5.2e-07 29.1 0.0 8.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Arf PF00025.16 CCF53691.1 - 8.1e-40 135.8 0.0 9.6e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCF53691.1 - 5.1e-17 61.7 0.0 6.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF53691.1 - 2.3e-10 40.9 0.0 3.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCF53691.1 - 2.2e-09 36.8 0.0 2.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCF53691.1 - 6.3e-08 32.0 0.0 7e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCF53691.1 - 2.3e-06 27.5 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CCF53691.1 - 1.1e-05 24.3 0.1 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 CCF53691.1 - 5e-05 22.8 0.0 0.012 15.0 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCF53691.1 - 0.0015 18.4 0.1 0.091 12.5 0.1 2.2 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 CCF53691.1 - 0.073 12.6 0.0 3.4 7.1 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCF53691.1 - 0.11 13.2 0.0 0.15 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Vps52 PF04129.7 CCF53692.1 - 1.3e-35 122.8 0.0 5.1e-27 94.5 0.0 2.8 3 0 0 3 3 3 2 Vps52 / Sac2 family Aconitase PF00330.15 CCF53692.1 - 0.038 12.4 0.1 0.062 11.7 0.1 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Pkinase PF00069.20 CCF53693.1 - 7.2e-64 215.4 0.0 1.6e-63 214.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF53693.1 - 6.3e-36 123.7 0.0 2.2e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCF53693.1 - 0.00028 19.9 0.3 0.0023 16.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CCF53693.1 - 0.0017 17.2 0.1 0.0029 16.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Sec10 PF07393.6 CCF53693.1 - 0.18 9.9 3.3 0.33 9.0 2.3 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF4219 PF13961.1 CCF53696.1 - 0.048 13.0 0.1 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Oxidored_FMN PF00724.15 CCF53697.1 - 6.3e-52 176.6 0.0 8.3e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 CCF53698.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCF53698.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 CCF53698.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pmp3 PF01679.12 CCF53699.1 - 2.1e-28 97.7 5.3 2.3e-28 97.6 3.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 CCF53699.1 - 7.6 6.2 6.0 0.94 9.1 1.0 1.8 2 0 0 2 2 2 0 Conserved TM helix adh_short PF00106.20 CCF53700.1 - 1.7e-27 96.3 0.9 2.7e-27 95.7 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF53700.1 - 1.6e-10 40.9 1.0 3.2e-10 39.9 0.7 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF53700.1 - 6.5e-09 35.9 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCF53700.1 - 0.00017 21.0 0.2 0.00028 20.3 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CHASE2 PF05226.6 CCF53700.1 - 0.04 13.1 0.0 0.084 12.1 0.0 1.6 1 1 0 1 1 1 0 CHASE2 domain DUF1776 PF08643.5 CCF53700.1 - 0.062 12.4 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Fungal_trans_2 PF11951.3 CCF53702.1 - 4.7e-41 140.6 0.9 3.4e-39 134.5 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53702.1 - 3.2e-07 30.1 9.0 5.2e-07 29.4 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 CCF53703.1 - 2.8e-21 74.9 3.9 4.7e-21 74.3 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCF53703.1 - 1.8e-16 59.8 13.7 3.4e-16 59.0 9.5 1.5 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CCF53703.1 - 1.7e-15 56.6 0.0 6.2e-14 51.6 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain A2L_zn_ribbon PF08792.5 CCF53703.1 - 0.077 12.4 0.0 0.077 12.4 0.0 3.7 3 1 1 4 4 4 0 A2L zinc ribbon domain DZR PF12773.2 CCF53703.1 - 7.1 6.5 9.9 76 3.2 6.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon Indigoidine_A PF04227.7 CCF53704.1 - 5.4e-115 383.6 0.6 6.4e-115 383.4 0.4 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Arm PF00514.18 CCF53704.1 - 0.13 12.1 0.2 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat AP_endonuc_2 PF01261.19 CCF53705.1 - 4.9e-15 55.4 0.1 1.4e-09 37.5 0.0 3.2 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel FKBP_C PF00254.23 CCF53706.1 - 7.2e-29 99.6 0.2 3.4e-28 97.5 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase YL1 PF05764.8 CCF53706.1 - 0.052 13.1 28.1 0.012 15.2 15.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein SDA1 PF05285.7 CCF53706.1 - 1.9 7.6 23.4 0.48 9.6 10.2 2.1 2 0 0 2 2 2 0 SDA1 BSP_II PF05432.6 CCF53706.1 - 2.2 7.4 21.0 2 7.5 1.7 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 CCF53706.1 - 3.8 7.0 18.2 4.9 6.7 8.0 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_hydro_92 PF07971.7 CCF53709.1 - 1e-112 377.4 0.0 1.4e-112 376.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 RVT_2 PF07727.9 CCF53710.1 - 2.8e-27 95.2 0.1 3.1e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_II PF05188.12 CCF53711.1 - 0.013 15.5 0.3 3.1 7.8 0.1 2.8 2 1 0 3 3 3 0 MutS domain II Tub_2 PF04525.7 CCF53712.1 - 1.3e-22 80.1 0.0 1.5e-22 79.8 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 DUF1295 PF06966.7 CCF53713.1 - 4.9e-49 166.7 0.0 7.8e-49 166.0 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 CCF53713.1 - 2.6e-05 24.3 0.0 7.9e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCF53713.1 - 0.00028 20.9 1.3 0.00077 19.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CCF53713.1 - 0.00028 20.6 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Choline_transpo PF04515.7 CCF53714.1 - 2.8e-87 292.5 28.0 2.8e-87 292.5 19.4 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter AMP-binding PF00501.23 CCF53715.1 - 1.6e-66 224.4 0.5 2.6e-65 220.4 0.4 2.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF53715.1 - 0.0001 23.1 0.0 0.00038 21.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain zf-DNL PF05180.7 CCF53717.1 - 1.3e-28 98.4 0.4 1.9e-28 97.9 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_5 PF13719.1 CCF53717.1 - 0.068 12.7 0.6 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCF53717.1 - 0.086 12.5 0.7 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 CCF53717.1 - 0.19 11.2 2.1 0.21 11.0 0.6 1.7 2 0 0 2 2 2 0 CSL zinc finger Zn-ribbon_8 PF09723.5 CCF53717.1 - 0.42 10.6 2.7 1.5 8.8 1.9 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Amidase PF01425.16 CCF53718.1 - 1.9e-89 300.5 0.0 2.3e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Arch_ATPase PF01637.13 CCF53719.1 - 9.6e-05 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 CCF53719.1 - 0.00096 19.1 0.3 0.01 15.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Nucleoplasmin PF03066.10 CCF53719.1 - 0.042 13.3 2.4 0.085 12.3 1.6 1.5 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CCF53719.1 - 1.1 9.0 4.7 3 7.6 3.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 CCF53719.1 - 3.6 6.7 7.5 5.6 6.1 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 CCF53719.1 - 9.7 3.9 5.3 14 3.3 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PUA PF01472.15 CCF53720.1 - 5.9e-20 70.7 0.1 8.4e-20 70.2 0.0 1.2 1 0 0 1 1 1 1 PUA domain SQS_PSY PF00494.14 CCF53721.1 - 1.3e-52 178.7 0.1 1.6e-52 178.4 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PTPLA PF04387.9 CCF53722.1 - 4.4e-53 179.0 6.1 4.4e-53 179.0 4.2 1.6 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA HlyIII PF03006.15 CCF53723.1 - 2e-49 168.0 17.1 2.6e-49 167.6 11.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.13 CCF53723.1 - 0.0048 16.4 1.6 0.0048 16.4 1.1 2.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain p450 PF00067.17 CCF53724.1 - 6.1e-83 278.8 0.0 7.5e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GDPD PF03009.12 CCF53725.1 - 3.6e-31 108.5 0.0 6.2e-31 107.8 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family AFG1_ATPase PF03969.11 CCF53727.1 - 1.8e-88 296.7 0.0 1e-86 291.0 0.0 2.3 2 0 0 2 2 2 1 AFG1-like ATPase AAA_22 PF13401.1 CCF53727.1 - 3.7e-06 27.1 0.0 3.3e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCF53727.1 - 8.2e-05 22.6 0.0 0.0011 19.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCF53727.1 - 0.0005 20.2 0.1 0.0029 17.7 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCF53727.1 - 0.051 13.7 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase RAP1 PF07218.6 CCF53727.1 - 0.37 8.8 3.8 0.6 8.1 2.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CCF53727.1 - 2.9 7.2 16.4 0.16 11.3 7.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyoxalase_2 PF12681.2 CCF53728.1 - 4.1e-19 69.1 0.0 6.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CCF53728.1 - 0.012 15.6 0.0 0.074 13.0 0.0 2.2 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ada_Zn_binding PF02805.11 CCF53728.1 - 0.048 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada MFS_1 PF07690.11 CCF53729.1 - 6.5e-33 113.9 26.8 5e-32 110.9 18.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PspB PF06667.7 CCF53729.1 - 0.024 14.5 0.2 0.39 10.6 0.0 2.5 2 0 0 2 2 2 0 Phage shock protein B TMEM237 PF15383.1 CCF53729.1 - 0.15 11.1 5.3 0.35 9.9 0.1 2.9 2 1 1 3 3 3 0 Transmembrane protein 237 Abhydrolase_6 PF12697.2 CCF53730.1 - 4.2e-26 92.2 0.7 7.7e-26 91.3 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF53730.1 - 1.3e-11 44.3 0.2 4e-11 42.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF53730.1 - 7.5e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCF53730.1 - 1.3e-05 25.0 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CCF53730.1 - 2.9e-05 24.4 0.0 5.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CCF53730.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CCF53730.1 - 0.00034 20.2 0.1 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF900 PF05990.7 CCF53730.1 - 0.0094 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.2 CCF53730.1 - 0.0096 14.8 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 CCF53730.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.17 CCF53730.1 - 0.039 13.6 0.1 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 CCF53730.1 - 0.082 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Sugar_tr PF00083.19 CCF53731.1 - 1.7e-49 168.6 20.7 2.3e-49 168.2 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53731.1 - 1.5e-25 89.6 30.4 6.6e-14 51.3 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.6 CCF53733.1 - 5.2e-27 94.6 0.0 1.1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 CCF53733.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF53733.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF53733.1 - 0.00043 19.9 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF53733.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF53733.1 - 0.0017 18.8 0.0 0.0028 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF53733.1 - 0.031 13.9 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DUF2608 PF11019.3 CCF53733.1 - 0.032 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF706 PF05153.10 CCF53736.1 - 4.6e-121 402.9 0.9 5.6e-121 402.6 0.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 CCF53736.1 - 0.0031 17.5 0.0 0.88 9.5 0.0 2.5 2 0 0 2 2 2 2 HD domain Pro_dh PF01619.13 CCF53737.1 - 5.7e-36 124.0 0.0 2.7e-18 66.0 0.0 3.3 2 1 0 2 2 2 2 Proline dehydrogenase PQ-loop PF04193.9 CCF53738.1 - 1.2e-20 72.8 22.6 9.3e-12 44.3 3.1 3.6 4 0 0 4 4 4 2 PQ loop repeat SKG6 PF08693.5 CCF53738.1 - 1.2 8.5 3.7 0.58 9.5 0.4 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MAGE_N PF12440.3 CCF53738.1 - 2.1 8.7 9.3 0.073 13.3 1.9 1.9 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF1049 PF06305.6 CCF53738.1 - 2.7 7.5 6.3 3.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) MtN3_slv PF03083.11 CCF53738.1 - 6.7 6.6 7.5 0.5 10.2 0.2 2.6 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Fungal_trans PF04082.13 CCF53739.1 - 1.4e-06 27.4 2.6 5.4e-05 22.1 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53739.1 - 4.1e-05 23.3 7.3 7.4e-05 22.5 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CCF53740.1 - 8.6e-40 136.5 44.7 8.6e-40 136.5 31.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF53740.1 - 2.5e-08 32.9 13.6 2.5e-08 32.9 9.4 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter Cofilin_ADF PF00241.15 CCF53740.1 - 0.043 13.6 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein Sdh5 PF03937.11 CCF53741.1 - 6.6e-24 83.3 1.7 1.1e-23 82.6 1.1 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase YCII PF03795.9 CCF53742.1 - 0.067 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 YCII-related domain Pyr_redox_2 PF07992.9 CCF53743.1 - 2.5e-26 92.8 9.4 1.2e-24 87.3 6.5 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CCF53743.1 - 9e-14 50.8 0.0 2.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 CCF53743.1 - 3.3e-13 49.8 9.7 2.2e-12 47.1 0.9 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF53743.1 - 5.3e-12 46.2 0.2 1.9e-07 31.3 0.0 3.4 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF53743.1 - 7e-05 21.8 1.5 1.1 8.0 0.1 3.2 2 1 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CCF53743.1 - 0.00023 20.9 1.3 0.01 15.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 CCF53743.1 - 0.00075 18.4 1.9 0.023 13.5 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CCF53743.1 - 0.0026 16.7 6.5 1.4 7.7 0.1 3.5 2 2 1 3 3 3 2 FAD dependent oxidoreductase Reductase_C PF14759.1 CCF53743.1 - 0.0034 17.6 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_7 PF13241.1 CCF53743.1 - 0.0083 16.3 1.9 0.9 9.8 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Rieske_2 PF13806.1 CCF53743.1 - 0.021 14.5 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DUF1188 PF06690.6 CCF53743.1 - 0.044 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.7 CCF53743.1 - 0.062 12.2 0.2 30 3.3 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCF53743.1 - 0.068 12.0 6.4 1.3 7.8 0.1 3.6 3 1 1 4 4 4 0 FAD binding domain HI0933_like PF03486.9 CCF53743.1 - 0.19 10.1 7.6 0.25 9.7 0.0 3.7 4 1 1 5 5 5 0 HI0933-like protein TrkA_N PF02254.13 CCF53743.1 - 0.78 9.7 5.3 3.7 7.5 0.2 3.0 3 1 0 3 3 3 0 TrkA-N domain Transaldolase PF00923.14 CCF53744.1 - 5.1e-45 153.8 0.8 7.8e-45 153.2 0.2 1.5 2 0 0 2 2 2 1 Transaldolase DUF844 PF05815.6 CCF53744.1 - 0.14 10.9 1.4 0.3 9.8 1.0 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DnaJ PF00226.26 CCF53746.1 - 2.7e-16 59.0 2.2 7e-16 57.7 1.5 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2924 PF11149.3 CCF53746.1 - 0.34 10.9 5.7 0.16 11.9 2.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) LcrG PF07216.7 CCF53746.1 - 4.5 7.3 11.5 0.11 12.4 1.1 2.8 1 1 2 3 3 3 0 LcrG protein zf-rbx1 PF12678.2 CCF53747.1 - 2e-07 30.9 3.5 3.6e-07 30.1 2.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCF53747.1 - 4.1e-06 26.5 7.4 7e-06 25.7 2.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCF53747.1 - 4.6e-05 22.9 0.3 0.00011 21.7 0.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF53747.1 - 0.022 14.7 6.8 0.071 13.1 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF53747.1 - 0.034 13.8 8.6 0.38 10.5 5.5 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 CCF53747.1 - 0.12 12.3 0.7 0.29 11.1 0.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 CCF53747.1 - 0.32 10.7 5.2 0.99 9.1 3.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF53747.1 - 3.4 7.5 7.6 18 5.2 5.3 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SDH_alpha PF03313.10 CCF53748.1 - 1.5e-98 329.3 0.1 2.2e-98 328.8 0.0 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 CCF53748.1 - 1.1e-53 181.5 0.2 3.5e-53 179.8 0.0 1.9 2 0 0 2 2 2 1 Serine dehydratase beta chain Zn_clus PF00172.13 CCF53749.1 - 0.003 17.4 6.4 0.0064 16.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_8 PF13523.1 CCF53750.1 - 3.8e-36 124.2 0.1 5.8e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 CCF53751.1 - 7.6e-33 112.8 0.5 1.2e-32 112.2 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF53751.1 - 7.3e-11 43.0 0.1 1.3e-10 42.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF53751.1 - 3.9e-06 26.5 0.0 8.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 CCF53751.1 - 0.0025 17.4 0.1 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_FMN PF00724.15 CCF53752.1 - 2.4e-51 174.7 0.0 5.1e-51 173.6 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2034 PF10356.4 CCF53753.1 - 1.6e-15 56.7 0.7 2e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CCF53753.1 - 7.2e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease TPR_11 PF13414.1 CCF53754.1 - 1.6e-21 75.7 1.9 2.4e-11 43.1 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCF53754.1 - 2.3e-16 58.6 0.0 1.3e-05 24.5 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCF53754.1 - 2.2e-14 52.1 0.7 1.1e-05 25.0 0.0 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCF53754.1 - 1.6e-13 50.9 1.1 4.3e-07 30.4 0.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCF53754.1 - 8.9e-12 44.7 1.8 4.1e-05 23.4 0.0 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCF53754.1 - 3e-11 42.6 0.4 0.0029 17.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF53754.1 - 6e-11 42.5 4.4 4.5e-05 23.6 0.3 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF53754.1 - 1.4e-09 37.6 4.1 0.0046 17.4 0.0 4.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCF53754.1 - 7.7e-07 28.4 0.2 0.24 11.2 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF53754.1 - 1.8e-05 24.7 4.4 0.051 13.7 0.1 3.4 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CCF53754.1 - 9.4e-05 21.6 0.4 0.00014 20.9 0.3 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCF53754.1 - 0.0003 20.3 1.6 4.6 7.2 0.0 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCF53754.1 - 0.001 19.3 0.9 0.11 12.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCF53754.1 - 0.0019 17.9 2.3 0.0088 15.8 0.1 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCF53754.1 - 0.091 12.8 6.8 0.3 11.2 0.1 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCF53754.1 - 4.8 7.2 8.6 43 4.2 0.5 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2580 PF10824.3 CCF53754.1 - 4.9 7.5 6.4 1.5 9.2 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) DDE_3 PF13358.1 CCF53755.1 - 4.4e-15 55.6 0.1 5e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 CCF53755.1 - 0.027 14.5 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain SUR7 PF06687.7 CCF53756.1 - 1.3e-08 34.6 9.5 4.7e-08 32.8 6.6 1.7 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCF53756.1 - 0.49 10.0 8.9 0.05 13.3 2.5 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RseC_MucC PF04246.7 CCF53756.1 - 7.2 6.1 8.6 3.9 7.0 0.5 2.9 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC RVT_2 PF07727.9 CCF53757.1 - 2.2e-06 26.8 0.0 2.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3524 PF12038.3 CCF53758.1 - 0.025 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) RCR PF12273.3 CCF53759.1 - 0.00043 20.8 16.8 0.0024 18.4 11.2 2.0 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 CCF53759.1 - 0.0026 17.0 5.4 0.0033 16.6 3.8 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 CCF53759.1 - 0.012 15.8 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CcmD PF04995.9 CCF53759.1 - 0.018 14.7 2.3 0.026 14.2 1.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Rax2 PF12768.2 CCF53759.1 - 0.041 13.0 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 CCF53759.1 - 0.063 13.6 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ALO PF04030.9 CCF53760.1 - 4.1e-70 236.3 4.2 2e-61 207.8 0.4 2.7 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCF53760.1 - 1.7e-18 66.4 0.1 3e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain N-SET PF11764.3 CCF53760.1 - 0.47 10.3 1.8 0.45 10.3 0.3 1.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N EI24 PF07264.6 CCF53762.1 - 1.1e-30 106.6 9.2 1.6e-30 106.1 6.4 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Aa_trans PF01490.13 CCF53763.1 - 8.9e-52 175.9 41.4 1e-51 175.7 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sigma_reg_N PF13800.1 CCF53763.1 - 0.22 11.5 0.1 0.22 11.5 0.0 3.5 5 0 0 5 5 5 0 Sigma factor regulator N-terminal HIG_1_N PF04588.8 CCF53764.1 - 5.1e-19 67.7 0.1 8.1e-19 67.1 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MFS_1 PF07690.11 CCF53766.1 - 4.6e-26 91.3 27.4 4.6e-26 91.3 19.0 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 CCF53766.1 - 0.0011 18.9 9.2 0.052 13.5 1.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) IncA PF04156.9 CCF53766.1 - 0.42 10.1 1.5 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 IncA protein Acyl_transf_3 PF01757.17 CCF53766.1 - 1 8.1 32.4 0.017 14.0 4.6 2.1 2 0 0 2 2 2 0 Acyltransferase family Rhodanese PF00581.15 CCF53767.1 - 1.3e-17 64.1 0.0 1.6e-10 41.3 0.0 2.9 2 1 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.1 CCF53767.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Sugar_tr PF00083.19 CCF53768.1 - 7.7e-116 387.3 26.4 8.9e-116 387.1 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53768.1 - 3.1e-21 75.4 45.9 1.4e-18 66.7 6.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3021 PF11457.3 CCF53769.1 - 1.6 8.6 4.6 11 5.8 3.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3021) UBN2 PF14223.1 CCF53770.1 - 0.00075 19.2 0.1 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Asp PF00026.18 CCF53771.1 - 1.2e-46 159.4 13.0 3.3e-46 158.0 9.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 CCF53771.1 - 8.2e-09 35.8 2.8 0.0039 17.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 CCF53771.1 - 0.00038 20.4 4.3 0.019 14.8 3.4 2.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 CCF53771.1 - 0.0056 16.4 0.1 0.13 12.1 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 CCF53771.1 - 0.067 12.7 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Ribonuc_L-PSP PF01042.16 CCF53772.1 - 1e-39 135.0 0.2 1.2e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rota_NSP3 PF01665.11 CCF53772.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 SET PF00856.23 CCF53773.1 - 0.0029 17.9 0.2 0.54 10.5 0.1 3.4 1 1 1 2 2 2 1 SET domain TP53IP5 PF15331.1 CCF53773.1 - 0.19 11.5 2.6 0.31 10.9 1.8 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Spore_coat_CotO PF14153.1 CCF53773.1 - 4.6 6.6 11.2 1.9 7.9 5.4 1.9 2 0 0 2 2 2 0 Spore coat protein CotO zf-UBR PF02207.15 CCF53774.1 - 2.2e-16 59.3 15.0 2.2e-16 59.3 10.4 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCF53774.1 - 1.3e-11 44.0 0.7 2.8e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS MSP1_C PF07462.6 CCF53774.1 - 0.018 13.4 1.7 0.032 12.6 1.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Fungal_trans PF04082.13 CCF53777.1 - 1.3e-15 56.9 0.1 3e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53777.1 - 8.9e-07 28.7 8.1 1.5e-06 28.0 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ICE2 PF08426.5 CCF53778.1 - 7.6e-51 173.0 3.7 1.8e-28 99.3 0.0 2.8 2 1 0 2 2 2 2 ICE2 DS PF01916.12 CCF53780.1 - 6.3e-134 445.7 0.0 7.4e-134 445.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF494 PF04361.8 CCF53780.1 - 0.0026 17.4 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF494) Abhydrolase_5 PF12695.2 CCF53781.1 - 0.00083 19.1 0.1 0.0017 18.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF53781.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 CCF53781.1 - 0.026 14.1 0.1 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) EXS PF03124.9 CCF53782.1 - 4.4e-78 262.7 0.0 6e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 EXS family DUF775 PF05603.7 CCF53783.1 - 1.3e-40 139.1 0.0 1.4e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Nop16 PF09420.5 CCF53784.1 - 4e-41 140.8 2.6 4.8e-41 140.5 1.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Glyco_trans_4_3 PF12000.3 CCF53784.1 - 0.053 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Gkycosyl transferase family 4 group MoaC PF01967.16 CCF53785.1 - 4.4e-47 159.1 0.0 7.1e-47 158.4 0.0 1.3 1 0 0 1 1 1 1 MoaC family Radical_SAM PF04055.16 CCF53785.1 - 1.1e-23 84.2 0.0 2e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Mob_synth_C PF06463.8 CCF53785.1 - 5.8e-18 64.8 0.1 5.8e-17 61.5 0.0 2.6 2 1 0 2 2 2 1 Molybdenum Cofactor Synthesis C Fer4_12 PF13353.1 CCF53785.1 - 1.7e-07 31.4 0.0 7.5e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 CCF53785.1 - 1.3e-06 28.4 0.0 4.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Host_attach PF10116.4 CCF53785.1 - 0.7 10.1 4.5 1.8 8.7 3.1 1.7 1 0 0 1 1 1 0 Protein required for attachment to host cells Xan_ur_permease PF00860.15 CCF53786.1 - 2.6e-59 200.6 28.5 2.6e-59 200.6 19.7 1.7 2 0 0 2 2 2 1 Permease family Lyase_aromatic PF00221.14 CCF53789.1 - 3.1e-160 533.6 2.3 3.1e-160 533.6 1.6 1.4 2 0 0 2 2 2 1 Aromatic amino acid lyase Hydantoinase_B PF02538.9 CCF53790.1 - 6.8e-185 615.2 0.1 2.8e-184 613.2 0.1 1.7 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase TBSV_P22 PF03558.8 CCF53790.1 - 0.033 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 TBSV core protein P21/P22 Proteasome_A_N PF10584.4 CCF53790.1 - 0.29 10.4 1.3 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Form_Nir_trans PF01226.12 CCF53793.1 - 2.9e-63 213.1 19.7 3.8e-63 212.7 13.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF3353 PF11833.3 CCF53793.1 - 0.71 9.3 5.6 0.26 10.7 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) HECT PF00632.20 CCF53794.1 - 1.7e-34 119.3 0.0 1e-33 116.8 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Neurochondrin PF05536.6 CCF53794.1 - 0.09 11.0 0.4 0.15 10.3 0.3 1.2 1 0 0 1 1 1 0 Neurochondrin Myc_N PF01056.13 CCF53794.1 - 0.33 10.0 8.8 0.57 9.2 6.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PRCC PF10253.4 CCF53794.1 - 1.2 9.8 5.3 2.3 8.8 3.7 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Abhydrolase_6 PF12697.2 CCF53795.1 - 1.2e-16 61.2 0.7 3.4e-12 46.7 0.3 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF53795.1 - 6e-14 52.0 0.0 1.6e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCF53795.1 - 3.5e-08 33.2 0.0 7.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CCF53795.1 - 1.7e-05 24.5 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CCF53795.1 - 0.0088 15.4 0.0 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 CCF53795.1 - 0.01 15.0 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 CCF53795.1 - 0.036 12.5 0.0 0.21 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 CCF53795.1 - 0.043 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family RRF PF01765.14 CCF53796.1 - 9.6e-44 148.7 0.2 1.4e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Seryl_tRNA_N PF02403.17 CCF53796.1 - 0.68 9.9 5.0 1.5 8.8 3.5 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TRAM_LAG1_CLN8 PF03798.11 CCF53797.1 - 9.6e-30 103.6 9.4 1.2e-29 103.2 6.5 1.1 1 0 0 1 1 1 1 TLC domain Smr PF01713.16 CCF53798.1 - 9.6e-14 51.3 0.0 3.3e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CCF53798.1 - 0.0053 16.2 0.2 0.55 9.7 0.0 3.3 3 0 0 3 3 3 1 CUE domain DapB_C PF05173.9 CCF53798.1 - 0.055 13.2 0.1 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Phage_rep_org_N PF09681.5 CCF53798.1 - 0.22 11.0 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Tox-GHH PF15636.1 CCF53798.1 - 2.1 8.0 4.3 0.73 9.5 0.0 2.4 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Abhydrolase_5 PF12695.2 CCF53799.1 - 5.7e-09 35.8 0.1 9.8e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF53799.1 - 5.1e-07 29.8 0.6 6.9e-07 29.3 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxidored-like PF09791.4 CCF53800.1 - 8.7e-07 28.2 9.1 1.5e-06 27.5 6.3 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal adh_short PF00106.20 CCF53802.1 - 2.1e-26 92.8 2.2 3.2e-26 92.2 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF53802.1 - 3.4e-25 89.2 1.4 4.3e-25 88.8 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF53802.1 - 1e-08 35.0 2.2 3e-08 33.5 1.6 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCF53802.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.16 CCF53802.1 - 0.02 14.6 0.8 0.12 12.1 0.5 2.1 1 1 0 1 1 1 0 ThiF family DUF1657 PF07870.6 CCF53802.1 - 0.025 14.2 1.1 0.05 13.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) UPRTase PF14681.1 CCF53803.1 - 1e-69 233.9 0.0 1.2e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCF53803.1 - 0.00015 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MFS_1 PF07690.11 CCF53804.1 - 9.4e-22 77.1 44.5 5.1e-16 58.3 15.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF53804.1 - 3.4e-18 65.4 25.9 2e-17 62.9 5.2 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Nodulin_late PF07127.6 CCF53804.1 - 0.0063 16.6 0.2 0.089 12.9 0.0 2.3 2 0 0 2 2 2 1 Late nodulin protein DJ-1_PfpI PF01965.19 CCF53805.1 - 3.1e-24 85.0 0.0 5.8e-24 84.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CCF53805.1 - 9e-16 57.1 0.1 1.7e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 CCF53806.1 - 1.2e-24 87.1 0.0 1.7e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF53806.1 - 1.8e-10 40.7 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCF53806.1 - 1.7e-05 24.7 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCF53806.1 - 0.002 17.6 0.1 0.0043 16.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CCF53806.1 - 0.013 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 CCF53806.1 - 0.014 15.5 0.1 0.034 14.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CCF53806.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CCF53806.1 - 0.042 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCF53806.1 - 0.05 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Zip PF02535.17 CCF53807.1 - 8.8e-54 182.6 9.4 1e-53 182.4 6.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HTH_23 PF13384.1 CCF53808.1 - 1.9e-07 30.4 0.0 0.0087 15.6 0.0 2.2 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4_2 PF08281.7 CCF53808.1 - 8.2e-06 25.1 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 Terminase_5 PF06056.7 CCF53808.1 - 0.00033 20.1 0.5 0.0043 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative ATPase subunit of terminase (gpP-like) HTH_24 PF13412.1 CCF53808.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 CCF53808.1 - 0.012 15.6 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Glycos_trans_3N PF02885.12 CCF53808.1 - 0.016 14.7 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain HTH_29 PF13551.1 CCF53808.1 - 0.02 15.0 0.0 0.25 11.5 0.0 2.1 1 1 1 2 2 2 0 Winged helix-turn helix GerE PF00196.14 CCF53808.1 - 0.024 13.9 0.2 0.65 9.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family CPSase_L_D3 PF02787.14 CCF53808.1 - 0.059 13.1 0.8 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_Tnp_ISL3 PF13542.1 CCF53808.1 - 0.073 12.2 0.0 0.78 8.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 RPA_C PF08784.6 CCF53808.1 - 0.089 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal HTH_23 PF13384.1 CCF53809.1 - 1e-06 28.1 0.1 1.6e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 CCF53809.1 - 2.6e-05 23.7 0.1 4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_38 PF13936.1 CCF53809.1 - 0.00011 21.6 0.4 0.00019 20.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.14 CCF53809.1 - 0.00026 20.2 0.1 0.00041 19.5 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_29 PF13551.1 CCF53809.1 - 0.00031 20.8 0.2 0.0013 18.8 0.0 2.0 1 1 1 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS1 PF12759.2 CCF53809.1 - 0.00067 19.0 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 InsA C-terminal domain AAA_30 PF13604.1 CCF53809.1 - 0.00089 18.8 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Crp PF00325.15 CCF53809.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family Sigma70_r4_2 PF08281.7 CCF53809.1 - 0.0032 16.9 0.1 0.0049 16.2 0.1 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_28 PF13518.1 CCF53809.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 CCF53809.1 - 0.0073 16.2 0.1 0.02 14.8 0.0 1.7 2 0 0 2 2 2 1 Transposase CENP-B_N PF04218.8 CCF53809.1 - 0.011 15.0 0.7 0.019 14.3 0.5 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TrmB PF01978.14 CCF53809.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.10 CCF53809.1 - 0.041 13.7 0.1 0.097 12.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_Tnp_ISL3 PF13542.1 CCF53809.1 - 0.054 12.6 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_Crp_2 PF13545.1 CCF53809.1 - 0.059 13.1 0.2 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_ECF PF07638.6 CCF53809.1 - 0.078 12.6 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor HTH_38 PF13936.1 CCF53810.1 - 2.9e-06 26.7 0.1 2.1e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 CCF53810.1 - 2.7e-05 23.6 0.1 4.3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 CCF53810.1 - 0.00071 19.7 0.6 0.055 13.6 0.0 2.2 1 1 2 3 3 3 2 Winged helix-turn helix GerE PF00196.14 CCF53810.1 - 0.0037 16.5 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 CCF53810.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 CCF53810.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2481 PF10654.4 CCF53810.1 - 0.087 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) F-box-like PF12937.2 CCF53811.1 - 0.0011 18.5 0.7 0.0024 17.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.3 CCF53811.1 - 0.0018 18.0 4.0 0.0024 17.6 1.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3760) Ytp1 PF10355.4 CCF53812.1 - 2.4e-80 269.6 13.6 2.4e-80 269.6 9.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCF53812.1 - 2.4e-28 97.8 2.9 2.4e-28 97.8 2.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) VIT1 PF01988.14 CCF53812.1 - 1.8 8.0 6.7 0.19 11.1 0.8 2.1 2 0 0 2 2 2 0 VIT family CTP_transf_2 PF01467.21 CCF53813.1 - 5.3e-15 55.8 0.4 1.1e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase Zip PF02535.17 CCF53813.1 - 0.011 14.7 8.7 0.24 10.3 6.9 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Innate_immun PF12782.2 CCF53813.1 - 1.6 7.9 14.5 4.2 6.5 10.0 1.7 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family MMtag PF10159.4 CCF53814.1 - 1.9e-29 101.5 2.5 1.9e-29 101.5 1.7 3.5 2 1 0 2 2 2 1 Kinase phosphorylation protein IMS PF00817.15 CCF53815.1 - 1.1e-37 129.1 0.0 2e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCF53815.1 - 9.2e-10 38.5 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Glyco_hydro_cc PF11790.3 CCF53816.1 - 3.6e-67 226.2 9.3 4.3e-67 226.0 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_53 PF07745.8 CCF53816.1 - 0.0014 17.4 0.1 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_39 PF01229.12 CCF53816.1 - 0.034 12.5 0.0 0.05 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Glyco_hydro_2_C PF02836.12 CCF53816.1 - 0.047 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain WI12 PF07107.6 CCF53816.1 - 0.15 12.0 1.0 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Wound-induced protein WI12 MFS_1 PF07690.11 CCF53817.1 - 1.2e-20 73.6 44.5 2.7e-11 42.7 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Neurensin PF14927.1 CCF53817.1 - 0.13 11.6 0.1 0.13 11.6 0.1 3.2 4 0 0 4 4 4 0 Neurensin Alpha-amylase PF00128.19 CCF53818.1 - 2.5e-14 53.4 0.0 4.9e-14 52.4 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain PAN_4 PF14295.1 CCF53819.1 - 0.14 11.9 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 PAN domain Cu-oxidase_2 PF07731.9 CCF53820.1 - 2.7e-40 137.0 3.6 8.2e-38 129.0 0.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CCF53820.1 - 7e-38 130.0 0.9 9.9e-35 119.7 0.0 2.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCF53820.1 - 1e-30 105.8 1.2 6.5e-26 90.3 0.1 4.0 4 0 0 4 4 4 2 Multicopper oxidase FTR1 PF03239.9 CCF53821.1 - 2.4e-52 177.7 14.1 4.5e-34 117.7 5.1 2.2 2 0 0 2 2 2 2 Iron permease FTR1 family Wzy_C PF04932.10 CCF53821.1 - 0.0022 17.8 5.1 0.013 15.3 1.2 2.4 2 0 0 2 2 2 1 O-Antigen ligase DUF788 PF05620.6 CCF53821.1 - 0.14 11.9 1.2 0.62 9.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF2142 PF09913.4 CCF53821.1 - 0.51 8.9 9.1 0.056 12.1 0.7 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) adh_short_C2 PF13561.1 CCF53823.1 - 2e-28 99.8 0.1 2.7e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCF53823.1 - 6e-28 97.8 0.0 9.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF53823.1 - 2.9e-13 49.8 0.0 4.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCF53823.1 - 0.013 14.4 0.2 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Dak1 PF02733.12 CCF53824.1 - 2.7e-108 361.3 0.0 3.6e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CCF53824.1 - 2.8e-43 147.6 0.6 5.4e-43 146.6 0.4 1.5 1 0 0 1 1 1 1 DAK2 domain DUF1769 PF08588.5 CCF53825.1 - 4.8e-18 64.8 0.6 1.2e-17 63.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Mpv17_PMP22 PF04117.7 CCF53826.1 - 4.8e-11 42.1 4.4 1.5e-09 37.3 1.8 2.3 1 1 1 2 2 2 2 Mpv17 / PMP22 family POR PF01558.13 CCF53826.1 - 0.005 16.7 0.3 0.34 10.8 0.1 2.9 1 1 1 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase WD40 PF00400.27 CCF53827.1 - 8.2e-36 120.6 2.0 2.3e-06 27.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.6 CCF53827.1 - 7.5e-31 105.6 1.3 1.3e-30 104.9 0.9 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 CCF53827.1 - 0.0058 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCF53827.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 U-box domain Nucleoporin_N PF08801.6 CCF53827.1 - 0.031 13.0 0.0 0.2 10.3 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like Fungal_trans PF04082.13 CCF53828.1 - 3e-31 108.2 0.1 7.2e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF53828.1 - 8.9e-12 44.7 9.0 1.5e-11 44.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1295 PF06966.7 CCF53828.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) TFIID-18kDa PF02269.11 CCF53829.1 - 2.6e-29 100.8 1.1 8.1e-29 99.2 0.3 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit RNase_P_Rpp14 PF01900.14 CCF53829.1 - 0.1 12.5 0.1 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Rpp14/Pop5 family DDHD PF02862.12 CCF53829.1 - 6.5 6.4 9.1 4.9 6.8 3.2 2.1 2 0 0 2 2 2 0 DDHD domain ADH_zinc_N PF00107.21 CCF53830.1 - 1.2e-09 37.8 2.2 1.2e-09 37.7 0.3 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF53830.1 - 2.9e-06 26.9 0.0 5.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aminotran_4 PF01063.14 CCF53831.1 - 9.4e-21 74.3 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 CCF53832.1 - 8.8e-30 103.5 32.7 1.4e-29 102.9 22.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 CCF53832.1 - 4.3 7.3 6.9 0.44 10.5 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Amidase PF01425.16 CCF53833.1 - 9e-76 255.4 0.0 3.7e-74 250.1 0.0 2.0 1 1 0 1 1 1 1 Amidase EutA PF06277.6 CCF53833.1 - 0.0025 16.4 0.0 0.0045 15.6 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutA UDPG_MGDP_dh_N PF03721.9 CCF53834.1 - 1.7e-58 197.0 0.2 1.6e-56 190.6 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 CCF53834.1 - 2.5e-34 117.5 0.2 2.6e-33 114.3 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 CCF53834.1 - 4.3e-31 106.9 0.0 1e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.12 CCF53834.1 - 0.00049 20.4 0.1 0.41 11.0 0.0 2.8 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCF53834.1 - 0.0033 17.2 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CCF53834.1 - 0.034 13.8 0.2 0.93 9.2 0.0 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Metallophos PF00149.23 CCF53835.1 - 0.00039 19.8 0.1 0.0025 17.2 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PG_binding_1 PF01471.13 CCF53835.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative peptidoglycan binding domain SpoIIE PF07228.7 CCF53836.1 - 1e-13 51.4 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCF53836.1 - 0.0004 19.8 0.0 0.044 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCF53836.1 - 0.00065 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1770 PF08589.5 CCF53837.1 - 9.7e-08 32.5 6.6 9.7e-08 32.5 4.6 2.5 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) WI12 PF07107.6 CCF53837.1 - 0.041 13.7 0.1 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 Wound-induced protein WI12 Acyl-CoA_dh_1 PF00441.19 CCF53838.1 - 5.5e-15 55.7 0.9 5.7e-14 52.4 0.1 2.6 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF53838.1 - 3.4e-07 29.6 0.0 7.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CCF53838.1 - 0.016 15.7 0.1 0.13 12.8 0.0 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain FMN_dh PF01070.13 CCF53839.1 - 1.4e-114 382.7 0.1 1.8e-114 382.2 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCF53839.1 - 1.3e-16 60.1 0.0 2.8e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCF53839.1 - 1.8e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCF53839.1 - 0.00049 19.0 0.3 0.0015 17.4 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 CCF53839.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Peptidase_M19 PF01244.16 CCF53839.1 - 0.057 12.3 0.0 0.19 10.6 0.0 1.9 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) SlyX PF04102.7 CCF53840.1 - 3.5 8.0 5.6 28 5.1 0.0 2.8 3 0 0 3 3 3 0 SlyX Usp PF00582.21 CCF53841.1 - 7.3e-18 65.1 0.8 1e-17 64.6 0.6 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF970 PF06153.6 CCF53841.1 - 0.052 13.5 0.5 0.58 10.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF970) CLP_protease PF00574.18 CCF53841.1 - 0.091 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Clp protease Polysacc_deac_1 PF01522.16 CCF53842.1 - 7.3e-14 51.4 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase GFA PF04828.9 CCF53842.1 - 2.5e-09 36.9 1.7 6.9e-08 32.3 1.2 2.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Mss4 PF04421.8 CCF53843.1 - 2e-08 33.9 1.7 0.00094 18.9 0.8 3.5 3 1 0 3 3 3 2 Mss4 protein Acetyltransf_1 PF00583.19 CCF53843.1 - 1.9e-06 27.7 0.1 4.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF53843.1 - 2.7e-05 24.2 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF53843.1 - 0.0081 16.0 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF53843.1 - 0.13 12.0 0.0 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein NARP1 PF12569.3 CCF53843.1 - 1.7 7.2 8.8 2.8 6.5 6.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.11 CCF53843.1 - 2.5 7.5 11.7 4.8 6.6 8.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Cellulase PF00150.13 CCF53844.1 - 1.7e-15 56.9 0.2 2.9e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NUP PF06516.6 CCF53844.1 - 0.017 13.9 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Abhydrolase_5 PF12695.2 CCF53845.1 - 1.9e-12 47.1 0.0 2.3e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCF53845.1 - 1.5e-09 37.7 0.1 2.2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCF53845.1 - 3e-07 30.5 0.3 3.8e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 CCF53845.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF900 PF05990.7 CCF53845.1 - 0.0039 16.5 0.0 0.035 13.4 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.3 CCF53845.1 - 0.024 14.4 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DUF2305 PF10230.4 CCF53845.1 - 0.029 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 CCF53845.1 - 0.068 12.3 0.0 0.18 11.0 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 CCF53845.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein DUF2103 PF09876.4 CCF53846.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) DUF1902 PF08972.6 CCF53846.1 - 0.062 12.8 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Abhydrolase_2 PF02230.11 CCF53847.1 - 2.5e-55 187.2 0.0 2.9e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCF53847.1 - 3.9e-14 52.6 0.0 5.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF53847.1 - 1.2e-11 44.9 0.5 3.7e-10 40.0 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCF53847.1 - 0.00016 20.9 0.1 0.022 13.9 0.0 2.4 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase PF00756.15 CCF53847.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.8 CCF53847.1 - 0.0012 18.2 0.0 0.012 15.0 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 CCF53847.1 - 0.0017 17.9 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CCF53847.1 - 0.0043 16.3 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 CCF53847.1 - 0.0098 14.4 0.0 0.017 13.6 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 CCF53847.1 - 0.01 15.0 0.0 0.56 9.4 0.0 2.2 1 1 1 2 2 2 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 CCF53847.1 - 0.013 15.0 0.2 0.17 11.4 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 CCF53847.1 - 0.031 14.0 0.1 0.07 12.8 0.1 1.5 2 0 0 2 2 2 0 Cutinase Lipase_3 PF01764.20 CCF53847.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF3857 PF12969.2 CCF53847.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) ADH_zinc_N PF00107.21 CCF53848.1 - 4e-27 94.3 0.2 6.4e-27 93.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF53848.1 - 2.8e-10 39.9 0.0 1.2e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCF53848.1 - 5.9e-10 40.1 0.3 2.6e-09 38.0 0.1 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DUF883 PF05957.8 CCF53849.1 - 9.6e-09 35.5 77.6 0.055 13.8 1.4 9.2 2 2 3 8 8 8 7 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CCF53849.1 - 0.027 13.9 30.4 0.25 10.8 2.2 4.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ApoO PF09769.4 CCF53849.1 - 0.11 12.2 0.2 0.11 12.2 0.1 5.6 2 1 3 6 6 6 0 Apolipoprotein O DUF1543 PF07566.7 CCF53849.1 - 1.6 8.3 44.7 1.9 8.0 0.4 10.6 9 3 3 12 12 12 0 Domain of Unknown Function (DUF1543) Acetyltransf_3 PF13302.1 CCF53850.1 - 2.4e-19 69.8 0.0 3.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF53850.1 - 5.5e-06 26.3 0.1 1.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF53850.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.21 CCF53851.1 - 3.7e-27 92.9 76.3 0.00045 20.4 0.4 10.6 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF53851.1 - 4.3e-19 67.3 75.6 0.0015 18.7 1.2 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF53851.1 - 4e-10 39.4 3.4 1.7e-06 28.0 0.1 11.3 12 2 0 12 12 12 3 Zinc-finger double domain zf-met PF12874.2 CCF53851.1 - 0.0033 17.5 26.3 1.4 9.2 0.0 8.4 10 0 0 10 10 10 3 Zinc-finger of C2H2 type Flagellin_IN PF07196.8 CCF53851.1 - 0.052 13.5 3.3 0.12 12.4 2.3 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif DUF1059 PF06348.6 CCF53851.1 - 0.06 13.1 5.2 4.9 7.0 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1059) AAR2 PF05282.6 CCF53851.1 - 0.06 12.2 0.9 0.1 11.4 0.6 1.5 1 0 0 1 1 1 0 AAR2 protein zf-C2H2_jaz PF12171.3 CCF53851.1 - 1.7 8.8 30.9 7.5 6.8 0.0 8.4 9 0 0 9 9 9 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCF53851.1 - 8.4 6.4 24.2 0.26 11.2 0.2 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-SNAP50_C PF12251.3 CCF53852.1 - 1.9e-13 50.2 0.0 6.9e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal GTP_EFTU PF00009.22 CCF53853.1 - 2.1e-58 196.8 0.2 3e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCF53853.1 - 2.9e-29 101.1 0.0 7.2e-29 99.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCF53853.1 - 3e-16 59.3 2.1 3e-16 59.3 1.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCF53853.1 - 1.7e-05 24.3 0.3 4.6e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCF53853.1 - 4.9e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CCF53853.1 - 0.046 13.1 0.6 0.099 12.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CCF53853.1 - 0.11 12.0 0.3 6.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Spt5-NGN PF03439.8 CCF53854.1 - 2.4e-20 72.0 0.0 4.4e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CCF53854.1 - 3e-18 64.7 7.5 4.2e-07 29.4 0.0 6.2 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.3 CCF53854.1 - 3.3e-15 56.4 18.5 3.3e-15 56.4 12.8 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 CCF53854.1 - 1.1e-08 35.4 12.5 1.1e-08 35.4 8.7 2.0 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Tox-HDC PF15656.1 CCF53854.1 - 0.016 15.4 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Dus PF01207.12 CCF53855.1 - 2.8e-45 154.4 0.1 7.5e-45 153.0 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 CCF53855.1 - 0.0063 15.5 0.0 0.0098 14.8 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PSRT PF07636.6 CCF53855.1 - 0.068 12.6 0.2 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 PSRT Spc7 PF08317.6 CCF53856.1 - 1.6e-29 102.6 4.3 2.6e-29 101.9 3.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 CCF53856.1 - 5.8e-06 24.6 29.8 5.8e-06 24.6 20.6 3.4 1 1 2 3 3 3 1 N-terminus of kinetochore NMS complex subunit Spc7 COG5 PF10392.4 CCF53856.1 - 0.023 14.6 4.3 0.069 13.1 3.0 1.9 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2605 PF10792.4 CCF53856.1 - 0.075 12.7 1.3 0.3 10.7 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) DUF1789 PF08748.6 CCF53856.1 - 0.47 10.5 7.5 0.064 13.3 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) CHCH PF06747.8 CCF53857.1 - 9.3e-07 28.6 1.3 1.2e-06 28.2 0.9 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCF53857.1 - 0.00028 20.6 1.0 0.00037 20.2 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HTH_5 PF01022.15 CCF53857.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family Sec61_beta PF03911.11 CCF53858.1 - 7.9e-18 63.9 1.4 9.9e-18 63.6 0.9 1.1 1 0 0 1 1 1 1 Sec61beta family Fasciclin PF02469.17 CCF53860.1 - 3.4e-23 82.0 0.7 2.3e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain YopH_N PF09013.5 CCF53860.1 - 0.0091 15.6 0.2 0.064 12.9 0.1 2.5 2 0 0 2 2 2 1 YopH, N-terminal SSP160 PF06933.6 CCF53860.1 - 0.051 11.5 14.3 0.067 11.1 9.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase PF00069.20 CCF53862.1 - 8.7e-07 28.3 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCF53862.1 - 1e-06 28.7 0.3 0.0046 16.7 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CCF53862.1 - 1.7e-06 27.2 0.0 1.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCF53862.1 - 0.00012 21.5 0.1 0.013 14.8 0.0 2.6 3 0 0 3 3 3 1 RIO1 family EcKinase PF02958.15 CCF53862.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 CCF53862.1 - 0.0076 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Polysacc_deac_3 PF15421.1 CCF53862.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Apc5 PF12862.2 CCF53863.1 - 1.3e-10 41.0 3.5 5.1e-10 39.0 0.6 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 DUF3730 PF12530.3 CCF53863.1 - 3.9e-10 40.0 2.8 7.7e-10 39.0 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) TPR_8 PF13181.1 CCF53863.1 - 0.38 10.6 3.6 5.7 6.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCF53863.1 - 0.84 10.3 24.0 0.22 12.2 1.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3752 PF12572.3 CCF53865.1 - 0.14 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Sec7 PF01369.15 CCF53866.1 - 3.7e-39 134.3 0.1 6.1e-39 133.6 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 CCF53866.1 - 6.4e-13 48.9 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CCF53866.1 - 9.7e-11 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 CCF53866.1 - 0.0031 17.5 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain adh_short PF00106.20 CCF53867.1 - 1.6e-64 216.7 6.6 3.7e-32 111.5 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCF53867.1 - 9.5e-33 113.3 3.0 3.2e-16 59.5 0.1 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CCF53867.1 - 2.4e-31 107.6 0.0 4.7e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CCF53867.1 - 9.8e-16 58.2 4.7 3.5e-07 30.2 0.2 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CCF53867.1 - 3.7e-07 29.9 0.0 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 CCF53867.1 - 0.00027 20.0 0.3 0.16 11.0 0.1 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 CCF53867.1 - 0.00064 19.2 2.8 0.16 11.3 0.2 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 CCF53867.1 - 0.0044 16.6 6.0 0.23 11.0 0.8 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.7 CCF53867.1 - 0.008 16.1 2.9 2.4 8.1 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF543) Polysacc_synt_2 PF02719.10 CCF53867.1 - 0.0082 15.0 0.5 0.027 13.3 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CCF53867.1 - 0.043 13.6 0.5 0.68 9.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Nro1 PF12753.2 CCF53867.1 - 3.4 6.5 3.8 5.6 5.8 2.6 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Cation_efflux PF01545.16 CCF53870.1 - 8e-50 169.5 0.4 1.3e-49 168.8 0.3 1.2 1 0 0 1 1 1 1 Cation efflux family PH PF00169.24 CCF53871.1 - 2.4e-39 133.7 0.1 1.2e-19 70.4 0.6 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 CCF53871.1 - 2.7e-21 75.9 6.3 4.3e-09 36.6 3.2 4.1 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 CCF53871.1 - 4.3e-19 68.3 4.1 8.8e-09 35.1 0.8 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 CCF53871.1 - 6e-12 45.4 3.0 1.7e-07 31.2 0.8 2.6 3 0 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 CCF53871.1 - 0.00019 21.3 1.9 0.38 10.6 0.1 3.1 3 0 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 CCF53871.1 - 0.00034 20.7 1.5 0.15 12.2 0.7 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH_4 PF15404.1 CCF53871.1 - 0.0025 17.3 1.1 6.9 6.1 0.1 3.3 2 1 1 3 3 3 2 Pleckstrin homology domain PH_7 PF15408.1 CCF53871.1 - 0.014 15.2 0.7 0.042 13.7 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain ESSS PF10183.4 CCF53872.1 - 2.1e-23 82.6 0.1 2.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 CCF53873.1 - 7.5e-70 236.1 1.3 1.1e-69 235.6 0.9 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 CCF53873.1 - 5.2e-10 39.2 0.2 1.9e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCF53873.1 - 0.00032 20.0 1.2 0.00074 18.7 0.8 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCF53873.1 - 0.022 14.5 0.3 0.022 14.5 0.2 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4115 PF13464.1 CCF53873.1 - 0.031 13.9 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) zf-AN1 PF01428.11 CCF53874.1 - 2.1e-17 62.6 34.1 5e-09 35.8 8.2 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger CDC27 PF09507.5 CCF53874.1 - 0.59 9.2 11.2 0.75 8.9 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 2OG-FeII_Oxy_2 PF13532.1 CCF53875.1 - 2.9e-25 89.2 0.0 4.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PK PF00224.16 CCF53876.1 - 5e-160 531.8 6.4 6.2e-160 531.5 4.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCF53876.1 - 4e-30 103.7 0.0 1e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCF53876.1 - 8.4e-05 21.5 0.3 0.00035 19.5 0.2 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 CCF53876.1 - 0.012 14.5 0.2 0.19 10.5 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Endonuc-PvuII PF09225.5 CCF53876.1 - 0.037 13.7 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII ELO PF01151.13 CCF53877.1 - 4e-65 219.5 8.1 4.8e-65 219.3 5.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LssY_C PF14067.1 CCF53878.1 - 0.048 12.6 0.5 1.2 8.0 0.3 2.1 2 0 0 2 2 2 0 LssY C-terminus SNAP PF14938.1 CCF53879.1 - 1.6e-98 329.3 14.7 1.7e-98 329.2 10.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CCF53879.1 - 3.7e-06 26.4 17.7 0.0043 16.6 2.9 4.4 1 1 3 4 4 4 3 TPR repeat TPR_12 PF13424.1 CCF53879.1 - 0.00019 21.2 16.1 0.004 17.0 0.2 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat Spatacsin_C PF14649.1 CCF53879.1 - 0.0056 15.5 4.0 0.031 13.1 2.8 1.9 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_16 PF13432.1 CCF53879.1 - 0.021 15.5 0.2 0.021 15.5 0.1 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF53879.1 - 0.027 14.2 10.9 2.1 8.3 0.0 5.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCF53879.1 - 0.083 12.7 4.1 1.8 8.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF53879.1 - 0.22 11.1 12.1 30 4.4 0.6 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF53879.1 - 1.6 9.3 17.6 0.94 10.0 0.2 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCF53879.1 - 6.5 7.4 8.1 9.1 7.0 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_5 PF13444.1 CCF53881.1 - 3.5e-06 27.5 0.0 0.00018 22.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCF53881.1 - 1.7e-05 24.7 0.1 0.0057 16.6 0.1 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF53881.1 - 0.0015 18.6 2.2 0.0061 16.6 1.4 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_60s PF00428.14 CCF53881.1 - 0.3 11.5 3.6 12 6.4 0.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAP_GLY PF01302.20 CCF53882.1 - 6.7e-26 89.7 3.0 9.8e-26 89.2 2.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCF53882.1 - 1.8e-15 56.9 0.0 1.4e-14 54.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-like domain RRM_1 PF00076.17 CCF53883.1 - 1.7e-42 142.8 0.3 4.9e-22 77.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF53883.1 - 5.7e-30 103.1 0.1 2.5e-15 56.2 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF53883.1 - 3.2e-23 81.3 0.1 4.1e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CCF53883.1 - 5.6e-16 58.5 0.1 1.9e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein MIP-T3 PF10243.4 CCF53883.1 - 1.4e-05 23.7 23.0 1.7e-05 23.5 15.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RRM_3 PF08777.6 CCF53883.1 - 0.0001 22.1 0.0 0.0001 22.1 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCF53883.1 - 0.16 11.7 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CDC27 PF09507.5 CCF53883.1 - 1 8.4 29.9 1.6 7.8 20.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 WD40 PF00400.27 CCF53884.1 - 7.8e-09 35.0 6.9 0.021 14.6 0.0 6.5 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 CCF53884.1 - 1.2e-05 25.0 0.0 0.63 9.7 0.0 4.7 4 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A DUF2348 PF09807.4 CCF53885.1 - 1.4e-09 37.4 0.1 3.1e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) Glycos_transf_1 PF00534.15 CCF53886.1 - 5.1e-30 104.1 0.0 1.3e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCF53886.1 - 2e-15 57.3 0.1 4.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CCF53886.1 - 3.4e-13 49.7 0.0 5.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CCF53886.1 - 2.7e-12 47.0 0.1 7.4e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCF53886.1 - 0.024 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 FCH PF00611.18 CCF53887.1 - 3.9e-20 71.8 0.4 3.9e-20 71.8 0.3 3.6 5 0 0 5 5 5 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CCF53887.1 - 4.7e-12 45.0 0.1 9.3e-12 44.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF53887.1 - 2.1e-10 39.9 0.0 3.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCF53887.1 - 2.7e-09 36.3 0.0 6.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1353 PF07087.6 CCF53887.1 - 0.0025 17.2 0.3 0.014 14.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1353) CorA PF01544.13 CCF53888.1 - 6.3e-13 48.4 11.0 3.1e-06 26.4 2.5 4.2 4 1 0 4 4 4 3 CorA-like Mg2+ transporter protein Yip1 PF04893.12 CCF53888.1 - 0.17 11.3 0.8 0.29 10.6 0.5 1.2 1 0 0 1 1 1 0 Yip1 domain COX7C PF02935.11 CCF53889.1 - 1.3e-08 34.5 3.4 2.4e-08 33.6 2.4 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Brix PF04427.13 CCF53890.1 - 1.3e-43 148.8 0.0 2e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 CCF53891.1 - 2.9e-24 83.9 11.5 4.1e-09 35.9 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CCF53891.1 - 0.0063 16.0 0.6 0.47 9.8 0.1 2.7 2 1 0 2 2 2 2 PQQ-like domain RAB3GAP2_N PF14655.1 CCF53891.1 - 0.06 12.3 0.0 0.68 8.8 0.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RVT_2 PF07727.9 CCF53892.1 - 9.4e-51 172.1 0.0 1e-38 132.7 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2370 PF10176.4 CCF53893.1 - 0.23 10.7 1.8 0.31 10.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FLO_LFY PF01698.11 CCF53893.1 - 2.1 7.1 7.8 2.3 6.9 5.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PGA2 PF07543.7 CCF53893.1 - 8.6 6.1 8.7 12 5.6 6.0 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 COesterase PF00135.23 CCF53894.1 - 5.4e-08 31.9 0.1 6.6e-08 31.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Zn_clus PF00172.13 CCF53895.1 - 0.089 12.7 7.2 0.23 11.3 5.0 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Leu_zip PF15294.1 CCF53895.1 - 0.091 11.8 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Leucine zipper CENP-P PF13096.1 CCF53896.1 - 0.0015 17.8 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF947 PF06102.7 CCF53897.1 - 1.7e-48 164.5 18.3 1.7e-48 164.5 12.7 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF947) Daxx PF03344.10 CCF53897.1 - 0.74 8.2 45.5 0.033 12.6 23.8 2.3 1 1 0 2 2 2 0 Daxx Family BING4CT PF08149.6 CCF53898.1 - 3.2e-35 119.4 0.0 7.3e-34 115.1 0.0 3.0 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 CCF53898.1 - 9.8e-10 37.9 0.0 6.2e-06 25.9 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCF53898.1 - 7e-05 21.8 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region GFO_IDH_MocA PF01408.17 CCF53899.1 - 2.6e-12 47.2 0.1 6.3e-12 46.0 0.1 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.1 CCF53899.1 - 0.047 13.8 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Syja_N PF02383.13 CCF53900.1 - 5.7e-90 301.3 0.1 7.3e-90 300.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain JAB PF01398.16 CCF53901.1 - 1.1e-21 76.7 0.1 2.2e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCF53901.1 - 4.5e-14 52.5 0.2 9.7e-14 51.4 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function SH2_2 PF14633.1 CCF53902.1 - 5.6e-70 234.8 0.4 5.6e-70 234.8 0.3 2.8 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 CCF53902.1 - 1.3e-29 102.6 0.6 1.3e-29 102.6 0.4 3.3 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 CCF53902.1 - 6.7e-24 83.9 0.0 1.6e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 CCF53902.1 - 4.9e-23 81.3 0.0 1.3e-22 79.9 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 CCF53902.1 - 4.1e-20 71.7 27.9 4.1e-20 71.7 19.3 5.4 3 1 1 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 CCF53902.1 - 1.2e-09 38.1 0.3 3.6e-09 36.6 0.2 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 CCF53902.1 - 0.00044 19.9 0.0 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Nucleo_P87 PF07267.6 CCF53903.1 - 2.9 6.4 6.3 3.4 6.2 4.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 CCF53903.1 - 7.7 6.8 6.2 27 5.1 4.3 2.0 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 CCF53904.1 - 1.4e-23 83.2 16.2 1.9e-19 69.6 0.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CCF53904.1 - 2.3e-14 53.2 6.1 3.2e-14 52.7 0.9 2.3 2 0 0 2 2 2 1 Nodulin-like Sugar_tr PF00083.19 CCF53904.1 - 0.00036 19.2 7.8 0.056 12.0 2.0 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF543 PF04418.7 CCF53904.1 - 0.017 15.0 0.6 1.3 9.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Rad21_Rec8_N PF04825.8 CCF53905.1 - 2.5e-28 98.2 0.0 3.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCF53905.1 - 1.3e-08 33.8 0.0 1.3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CCF53905.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 ScpA/B protein Spc7_N PF15402.1 CCF53905.1 - 0.14 10.1 3.2 0.19 9.6 2.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Peptidase_M1 PF01433.15 CCF53907.1 - 1.3e-66 225.3 0.0 1.8e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CCF53907.1 - 3.1e-43 146.8 0.3 6.6e-43 145.7 0.0 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCF53907.1 - 1.9e-14 53.7 0.0 5.2e-14 52.3 0.0 1.7 1 1 1 2 2 2 1 Peptidase MA superfamily IPPT PF01715.12 CCF53908.1 - 1.6e-44 151.8 4.5 1.4e-21 76.6 2.6 2.7 1 1 1 2 2 2 2 IPP transferase DUF3088 PF11287.3 CCF53908.1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Autophagy_N PF03986.8 CCF53909.1 - 2.9e-47 160.0 0.2 1.1e-46 158.2 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CCF53909.1 - 1.3e-24 86.0 0.1 2.8e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CCF53909.1 - 1e-13 50.1 0.5 1.6e-13 49.4 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal IFT43 PF15305.1 CCF53909.1 - 1.3 9.0 4.1 1.5 8.8 1.7 1.9 1 1 1 2 2 2 0 Intraflagellar transport protein 43 Gly-zipper_OmpA PF13436.1 CCF53909.1 - 2.4 7.8 13.5 0.11 12.1 5.5 1.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain RHD PF00554.17 CCF53910.1 - 0.043 13.5 0.1 0.05 13.3 0.1 1.1 1 0 0 1 1 1 0 Rel homology domain (RHD) BLUF PF04940.7 CCF53911.1 - 8e-32 108.8 0.0 1.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Sensors of blue-light using FAD NUC153 PF08159.7 CCF53912.1 - 2.2e-13 49.5 7.0 3.2e-09 36.2 0.0 3.8 3 0 0 3 3 3 3 NUC153 domain LSM PF01423.17 CCF53913.1 - 4.4e-20 70.9 0.1 5.3e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Bud13 PF09736.4 CCF53914.1 - 1.4e-44 151.9 8.5 1.4e-44 151.9 5.9 2.9 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF243 PF03103.12 CCF53914.1 - 0.067 13.3 1.0 0.21 11.7 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF243) MFS_1 PF07690.11 CCF53916.1 - 1.7e-06 26.9 31.3 0.00062 18.5 2.4 4.7 3 1 0 4 4 4 4 Major Facilitator Superfamily VirB8 PF04335.8 CCF53916.1 - 0.11 12.1 0.0 4.6 6.7 0.0 2.8 2 0 0 2 2 2 0 VirB8 protein Bombesin PF02044.12 CCF53917.1 - 7 6.2 9.0 13 5.4 1.3 2.4 2 0 0 2 2 2 0 Bombesin-like peptide Zn_clus PF00172.13 CCF53918.1 - 5.5e-05 22.9 6.0 0.00011 22.0 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Grp1_Fun34_YaaH PF01184.14 CCF53919.1 - 4.7e-83 277.6 14.8 5.4e-83 277.4 10.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 CCF53919.1 - 0.3 10.0 2.9 0.36 9.7 1.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Methyltransf_33 PF10017.4 CCF53920.1 - 2e-34 118.2 0.1 3.4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 CCF53920.1 - 5.7e-22 78.3 2.0 9.8e-13 48.0 0.1 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 dCMP_cyt_deam_1 PF00383.17 CCF53920.1 - 4e-21 74.5 0.0 6.8e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCF53920.1 - 3.5e-05 23.6 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Bd3614-like deaminase DinB_2 PF12867.2 CCF53920.1 - 0.00012 22.4 3.8 0.00012 22.3 1.5 2.0 2 0 0 2 2 2 1 DinB superfamily Ribosomal_L31e PF01198.14 CCF53921.1 - 1.4e-36 123.9 2.5 1.8e-36 123.6 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e JAB PF01398.16 CCF53922.1 - 9.5e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4203 PF13886.1 CCF53923.1 - 8.8e-27 93.9 22.0 8.8e-27 93.9 15.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) ERM PF00769.14 CCF53923.1 - 0.0035 16.9 8.0 0.0035 16.9 5.6 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Pro_CA PF00484.14 CCF53924.1 - 4.5e-39 133.8 0.1 7e-39 133.2 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 CCF53924.1 - 0.083 12.7 2.2 5.2 6.8 1.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.17 CCF53925.1 - 3.5e-57 193.9 0.0 7.9e-57 192.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 CCF53927.1 - 2.4e-61 206.6 3.0 2.4e-61 206.6 2.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCF53927.1 - 6.7e-35 120.2 3.9 6.7e-35 120.2 2.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCF53927.1 - 1.7e-29 103.7 0.0 1e-27 97.9 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF53927.1 - 2e-16 59.6 0.0 4.5e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCF53927.1 - 1.1e-15 56.8 0.2 1.1e-15 56.8 0.1 3.0 4 0 0 4 4 4 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CCF53927.1 - 5.1e-11 43.1 0.0 1.2e-10 41.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCF53927.1 - 0.003 17.1 0.1 0.024 14.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Macoilin PF09726.4 CCF53927.1 - 2.3 6.3 6.4 3.9 5.6 4.5 1.3 1 0 0 1 1 1 0 Transmembrane protein BAF1_ABF1 PF04684.8 CCF53927.1 - 8.8 5.0 25.2 26 3.5 17.3 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor HSP9_HSP12 PF04119.7 CCF53928.1 - 4.6e-21 74.6 11.9 9.4e-21 73.6 6.2 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 CCF53928.1 - 0.22 11.6 8.1 2.3 8.4 2.1 2.3 1 1 1 2 2 2 0 MT0933-like antitoxin protein Sugar_tr PF00083.19 CCF53929.1 - 2e-22 79.4 5.8 2e-22 79.4 4.1 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 CCF53929.1 - 5.9e-19 68.0 56.8 5.8e-15 54.8 19.2 3.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CCF53929.1 - 0.19 11.5 3.4 0.12 12.1 0.3 2.2 2 0 0 2 2 2 0 MFS_1 like family RVT_2 PF07727.9 CCF53930.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Orthopox_B11R PF07033.6 CCF53930.1 - 0.14 11.6 0.2 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Mito_carr PF00153.22 CCF53931.1 - 2.1e-63 210.0 4.4 6.5e-21 73.8 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein MSC PF09402.5 CCF53932.1 - 1.2e-82 277.3 0.0 1.6e-82 276.8 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCF53932.1 - 3.1e-14 52.2 0.0 3.1e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.22 CCF53932.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 SAP domain FAD_binding_3 PF01494.14 CCF53935.1 - 2.3e-28 99.2 0.0 6.5e-28 97.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCF53935.1 - 3.7e-07 30.4 0.3 0.00037 20.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCF53935.1 - 6.4e-07 28.6 0.2 0.0054 15.6 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF53935.1 - 0.00043 20.2 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCF53935.1 - 0.0018 18.1 0.1 0.01 15.7 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCF53935.1 - 0.06 12.1 0.0 0.097 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 CCF53935.1 - 0.098 11.2 0.1 2.1 6.8 0.1 2.6 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.5 CCF53935.1 - 0.11 11.3 0.0 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 CCF53935.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spc24 PF08286.6 CCF53938.1 - 1.8e-21 76.0 4.3 1.8e-21 76.0 3.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Herpes_UL6 PF01763.11 CCF53938.1 - 0.0047 15.1 2.4 0.0057 14.9 1.6 1.2 1 0 0 1 1 1 1 Herpesvirus UL6 like BBP1_C PF15272.1 CCF53938.1 - 0.023 14.2 6.9 0.031 13.8 4.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Sec2p PF06428.6 CCF53938.1 - 0.047 13.5 10.8 0.13 12.1 6.2 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.3 CCF53938.1 - 0.05 13.4 12.9 0.14 11.9 7.7 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 CCF53938.1 - 0.32 9.3 4.9 0.42 8.9 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MCPsignal PF00015.16 CCF53938.1 - 0.4 10.1 7.4 0.62 9.5 5.1 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.7 CCF53938.1 - 0.4 10.9 3.6 4.7 7.5 2.5 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 CCF53938.1 - 1.1 7.0 4.8 1.2 6.9 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nsp1_C PF05064.8 CCF53938.1 - 1.6 8.4 11.9 1.8 8.2 5.6 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region RasGAP_C PF03836.10 CCF53938.1 - 2.8 7.6 11.9 1.5 8.4 3.1 2.2 1 1 1 2 2 2 0 RasGAP C-terminus DivIVA PF05103.8 CCF53938.1 - 4.1 7.4 12.7 13 5.7 0.5 2.6 1 1 1 2 2 2 0 DivIVA protein DivIC PF04977.10 CCF53938.1 - 8.3 5.9 11.3 16 5.0 4.5 2.4 1 1 1 2 2 2 0 Septum formation initiator Vac_ImportDeg PF09783.4 CCF53939.1 - 3.3e-57 192.8 0.0 1e-51 174.9 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein DJ-1_PfpI_N PF13587.1 CCF53939.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Gpi1 PF05024.10 CCF53940.1 - 5.9e-39 133.6 12.5 8.8e-39 133.1 8.7 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Aldedh PF00171.17 CCF53941.1 - 3e-125 418.1 0.1 3.7e-125 417.8 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCF53941.1 - 0.0022 16.8 0.0 0.012 14.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) AA_kinase PF00696.23 CCF53942.1 - 2.6e-40 138.5 0.4 3.8e-40 137.9 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCF53942.1 - 6.1e-10 38.6 0.4 0.00014 21.5 0.0 3.0 3 0 0 3 3 3 2 PUA domain AAA PF00004.24 CCF53943.1 - 3.1e-17 63.0 0.2 1.6e-16 60.7 0.0 2.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCF53943.1 - 5.7e-14 52.0 0.0 3e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCF53943.1 - 7.3e-12 45.1 0.1 2e-11 43.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CCF53943.1 - 1.4e-10 40.5 0.2 7e-07 28.2 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCF53943.1 - 1.2e-08 35.1 1.0 2.7e-05 24.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCF53943.1 - 2.3e-05 24.4 0.1 0.00065 19.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CCF53943.1 - 2.7e-05 23.8 0.1 0.0001 22.0 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 CCF53943.1 - 3.4e-05 23.0 0.0 7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CCF53943.1 - 4.9e-05 23.0 0.0 0.00011 21.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF53943.1 - 8e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCF53943.1 - 0.00073 18.7 0.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCF53943.1 - 0.00083 19.0 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CCF53943.1 - 0.0012 18.4 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCF53943.1 - 0.0047 16.8 0.0 0.016 15.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 CCF53943.1 - 0.0047 16.3 0.1 0.13 11.6 0.0 2.4 2 1 1 3 3 3 1 AAA-like domain AAA_30 PF13604.1 CCF53943.1 - 0.0065 16.0 0.0 0.031 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCF53943.1 - 0.0087 15.4 0.1 0.027 13.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCF53943.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DEAD PF00270.24 CCF53943.1 - 0.016 14.6 0.2 0.25 10.8 0.0 2.5 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.6 CCF53943.1 - 0.018 14.6 0.2 0.07 12.7 0.0 2.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCF53943.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCF53943.1 - 0.029 15.1 0.0 0.069 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CCF53943.1 - 0.035 13.0 0.0 0.079 11.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CCF53943.1 - 0.039 13.8 0.0 0.098 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCF53943.1 - 0.041 13.3 0.1 0.15 11.4 0.0 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_2 PF07724.9 CCF53943.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 CCF53943.1 - 0.071 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 CCF53943.1 - 0.085 12.6 0.0 0.29 10.9 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CCF53943.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 CCF53943.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain CAF1A PF12253.3 CCF53944.1 - 2.3e-22 78.8 5.5 2.3e-22 78.8 3.8 2.8 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CCF53944.1 - 6.1e-07 29.0 21.5 6.1e-07 29.0 14.9 4.6 5 2 0 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2361 PF10153.4 CCF53944.1 - 3 8.0 20.3 29 4.9 11.5 3.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 CCF53945.1 - 1.5e-58 192.6 19.9 3.9e-10 39.1 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCF53945.1 - 6.2e-07 29.3 0.0 0.0049 16.6 0.0 3.0 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CCF53945.1 - 0.012 15.4 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MGC-24 PF05283.6 CCF53945.1 - 0.61 9.8 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) MgtE PF01769.11 CCF53946.1 - 3.3e-25 88.9 31.5 2.2e-09 37.6 0.7 5.0 4 1 0 4 4 4 3 Divalent cation transporter TMA7 PF09072.5 CCF53947.1 - 1.1e-19 70.6 17.7 1.5e-19 70.2 12.3 1.3 1 1 0 1 1 1 1 Translation machinery associated TMA7 DUF1154 PF06631.6 CCF53947.1 - 0.15 11.7 5.1 0.94 9.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Tetraspannin PF00335.15 CCF53948.1 - 8.2e-06 25.2 2.4 8.2e-06 25.2 1.7 1.8 1 1 2 3 3 3 1 Tetraspanin family MFS_1 PF07690.11 CCF53949.1 - 6.1e-28 97.5 54.2 6e-15 54.8 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1325 PF07039.6 CCF53951.1 - 7.4e-37 125.8 0.0 1e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SP2 PF03014.9 CCF53951.1 - 0.034 12.0 2.6 0.045 11.6 1.8 1.1 1 0 0 1 1 1 0 Structural protein 2 LBR_tudor PF09465.5 CCF53951.1 - 0.035 13.7 0.2 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain Agenet PF05641.7 CCF53951.1 - 0.069 13.3 0.1 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Agenet domain E1-E2_ATPase PF00122.15 CCF53952.1 - 4.3e-47 160.0 0.7 9.5e-47 158.9 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCF53952.1 - 1.4e-40 140.0 3.2 1.8e-40 139.6 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCF53952.1 - 4.9e-28 97.0 0.1 3.5e-13 49.4 0.1 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CCF53952.1 - 7.8e-16 58.8 0.0 1.9e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCF53952.1 - 2e-05 24.3 0.7 0.011 15.3 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCF53952.1 - 0.019 14.8 0.0 0.25 11.2 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF2638 PF10937.3 CCF53954.1 - 4.7 8.2 6.7 1.4 9.9 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2638) FMO-like PF00743.14 CCF53955.1 - 3.8e-27 94.7 0.0 9.5e-17 60.3 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCF53955.1 - 3.5e-15 56.6 0.0 7.1e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF53955.1 - 2.9e-09 37.0 0.0 0.0088 15.9 0.0 3.1 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF53955.1 - 9.7e-09 35.1 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 CCF53955.1 - 7.8e-07 28.3 0.0 0.00054 18.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCF53955.1 - 4.5e-06 26.6 0.1 4e-05 23.5 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCF53955.1 - 0.0015 17.4 0.1 0.0045 15.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCF53955.1 - 0.02 13.3 0.0 0.17 10.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 CCF53955.1 - 0.037 13.0 0.0 0.15 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Formyl_trans_N PF00551.14 CCF53956.1 - 9e-36 123.1 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 CCF53956.1 - 2.5e-07 30.0 0.0 6.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 CCF53956.1 - 1.4e-05 24.7 0.0 4.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ACT domain Gtr1_RagA PF04670.7 CCF53957.1 - 4.8e-87 290.9 0.0 7.7e-87 290.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCF53957.1 - 1.2e-05 24.7 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CCF53957.1 - 0.00023 21.0 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CCF53957.1 - 0.00039 19.7 0.0 0.00067 18.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCF53957.1 - 0.0013 19.2 0.0 0.0044 17.5 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCF53957.1 - 0.026 14.0 0.2 0.076 12.4 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CCF53957.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 CCF53957.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Smg4_UPF3 PF03467.10 CCF53958.1 - 1.3e-31 109.8 0.0 5.5e-31 107.9 0.0 2.0 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_2 PF04059.7 CCF53958.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 SYF2 PF08231.7 CCF53959.1 - 1.5e-39 135.6 17.2 2.8e-39 134.6 11.9 1.5 1 0 0 1 1 1 1 SYF2 splicing factor Cellulase PF00150.13 CCF53960.1 - 3.5e-18 65.7 1.3 3.5e-18 65.7 0.9 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UPF1_Zn_bind PF09416.5 CCF53961.1 - 2.5e-73 244.6 8.0 3.2e-73 244.3 4.0 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCF53961.1 - 2.6e-59 199.9 0.0 5.4e-59 198.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCF53961.1 - 4.6e-54 183.5 1.6 7.2e-54 182.8 1.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCF53961.1 - 6.1e-12 45.5 0.1 1.3e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF53961.1 - 7.1e-12 44.9 0.1 2e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CCF53961.1 - 1.5e-06 28.1 0.0 3.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 CCF53961.1 - 2.7e-05 23.7 0.3 0.29 10.6 0.0 3.2 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCF53961.1 - 5.2e-05 22.3 1.1 0.0013 17.7 0.0 2.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CCF53961.1 - 0.00075 19.1 0.0 0.0017 18.0 0.0 1.7 1 1 0 1 1 1 1 Helicase Ribosomal_S13_N PF08069.7 CCF53961.1 - 0.0018 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 CCF53961.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 CCF53961.1 - 0.014 14.3 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 CCF53961.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.24 CCF53961.1 - 0.026 14.0 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 CCF53961.1 - 0.034 13.0 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 CCF53961.1 - 0.077 12.2 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 CCF53961.1 - 0.13 11.3 0.0 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 KaiC SRP54 PF00448.17 CCF53961.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1664 PF07889.7 CCF53962.1 - 9.9 5.9 7.0 3.1 7.6 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Response_reg PF00072.19 CCF53963.1 - 1.9e-21 76.1 0.0 4.8e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.14 CCF53963.1 - 0.041 12.5 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ribosomal_S6 PF01250.12 CCF53964.1 - 1.9e-13 50.0 0.0 2.3e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 WD40 PF00400.27 CCF53965.1 - 1.1e-05 25.0 8.9 0.31 11.0 0.0 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CCF53965.1 - 0.00048 20.3 0.2 0.019 15.2 0.1 3.2 2 0 0 2 2 2 1 PQQ-like domain TFIIF_alpha PF05793.7 CCF53965.1 - 8.9 4.5 8.9 14 3.8 6.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 CCF53965.1 - 9.5 6.6 9.2 0.96 9.7 2.8 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DEAD PF00270.24 CCF53966.1 - 3e-28 98.4 0.4 1.2e-27 96.4 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF53966.1 - 9.1e-23 79.9 0.0 2.7e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCF53966.1 - 0.045 13.8 0.9 0.47 10.6 0.7 2.6 1 1 0 1 1 1 0 AAA domain EF-hand_8 PF13833.1 CCF53967.1 - 0.0076 15.8 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair Rib PF08428.5 CCF53967.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat Mito_carr PF00153.22 CCF53969.1 - 6.4e-60 198.8 2.6 7.6e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.14 CCF53970.1 - 8.9e-27 93.3 12.5 1.1e-26 93.0 8.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TctA PF01970.11 CCF53970.1 - 0.059 11.7 0.1 0.059 11.7 0.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Pinin_SDK_N PF04697.8 CCF53970.1 - 0.065 13.2 0.2 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 pinin/SDK conserved region F-box-like PF12937.2 CCF53971.1 - 0.00023 20.8 0.2 0.00094 18.8 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 CCF53971.1 - 0.053 13.1 0.1 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 F-box domain CAP_N PF01213.14 CCF53972.1 - 9e-96 320.8 14.7 4.9e-95 318.4 10.2 2.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCF53972.1 - 4.8e-61 204.7 1.0 6.3e-61 204.3 0.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CCF53972.1 - 0.0011 18.3 2.4 0.002 17.5 1.7 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 CCF53972.1 - 0.017 14.5 9.4 0.41 9.9 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator 4HBT_3 PF13622.1 CCF53972.1 - 0.088 12.5 10.9 0.3 10.7 0.2 2.7 2 1 0 3 3 3 0 Thioesterase-like superfamily Ndc80_HEC PF03801.8 CCF53973.1 - 3.9e-38 130.4 0.0 1.4e-37 128.5 0.0 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family OstA PF03968.9 CCF53973.1 - 0.036 14.0 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 OstA-like protein Flag1_repress PF03614.8 CCF53973.1 - 0.044 13.3 0.6 0.091 12.3 0.4 1.5 1 0 0 1 1 1 0 Repressor of phase-1 flagellin GAS PF13851.1 CCF53973.1 - 0.77 8.9 42.1 1.7 7.7 3.9 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Cellulase PF00150.13 CCF53974.1 - 5.7e-11 42.1 0.0 3.7e-08 32.9 0.0 2.9 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) DPBB_1 PF03330.13 CCF53975.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 1.9 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cwf_Cwc_15 PF04889.7 CCF53975.1 - 0.0026 17.4 5.5 0.0038 16.9 3.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 CCF53975.1 - 0.0036 15.7 22.8 0.0044 15.4 15.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 CCF53975.1 - 0.0062 15.8 8.6 0.0089 15.3 6.0 1.2 1 0 0 1 1 1 1 SDA1 PBP1_TM PF14812.1 CCF53975.1 - 0.22 11.8 7.6 0.51 10.6 5.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 CCF53975.1 - 0.26 10.8 12.3 0.36 10.4 8.5 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 CCF53975.1 - 0.28 9.0 10.9 0.36 8.7 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family Rib_hydrolayse PF02267.12 CCF53975.1 - 0.4 9.9 0.1 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosyl cyclase DUF2457 PF10446.4 CCF53975.1 - 0.75 8.4 17.4 1.1 7.8 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 CCF53975.1 - 1.6 8.1 5.2 2.6 7.5 3.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin Utp14 PF04615.8 CCF53975.1 - 2.8 6.0 18.7 3.6 5.6 13.0 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 CCF53975.1 - 5.1 5.0 12.0 6.7 4.6 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1183 PF06682.7 CCF53975.1 - 5.5 6.4 12.8 9.5 5.7 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Glypican PF01153.14 CCF53975.1 - 5.7 5.4 7.0 8 4.9 4.9 1.2 1 0 0 1 1 1 0 Glypican DUF506 PF04720.7 CCF53975.1 - 6.3 6.3 9.3 9 5.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) NAM-associated PF14303.1 CCF53975.1 - 7.2 6.9 10.5 12 6.2 7.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Abhydrolase_6 PF12697.2 CCF53976.1 - 4e-12 46.4 1.9 2.3e-11 44.0 1.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF53976.1 - 3e-06 27.0 0.0 2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF53976.1 - 4.8e-05 23.0 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold GAGE PF05831.6 CCF53978.1 - 0.029 14.4 0.5 0.035 14.2 0.4 1.1 1 0 0 1 1 1 0 GAGE protein RRM_1 PF00076.17 CCF53980.1 - 2.4e-09 36.7 0.0 2.8e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF53980.1 - 4.2e-09 36.2 0.0 2.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF53980.1 - 1.4e-06 28.0 0.0 0.0039 17.0 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-N PF14463.1 CCF53980.1 - 0.011 15.3 0.2 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 E1 N-terminal domain GAS2 PF02187.12 CCF53981.1 - 6.9e-08 32.1 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain adh_short PF00106.20 CCF53982.1 - 4.3e-27 95.0 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF53982.1 - 5.7e-12 45.9 0.0 7.1e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCF53982.1 - 2.5e-11 43.5 0.1 5.9e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 CCF53982.1 - 3.2e-07 29.7 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CCF53982.1 - 0.00042 20.0 0.1 0.00089 18.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCF53982.1 - 0.00049 19.6 0.1 0.0024 17.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCF53982.1 - 0.019 15.0 0.1 0.033 14.1 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 CCF53982.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LytR_C PF13399.1 CCF53982.1 - 0.072 13.4 0.3 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Fasciclin PF02469.17 CCF53983.1 - 5.6e-54 181.5 0.0 1.3e-13 51.0 0.0 6.9 7 0 0 7 7 7 6 Fasciclin domain RINGv PF12906.2 CCF53984.1 - 1.4e-12 47.4 4.6 2.4e-12 46.7 3.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCF53984.1 - 0.042 13.6 2.6 0.094 12.5 1.8 1.6 1 0 0 1 1 1 0 Ring finger domain HemY_N PF07219.8 CCF53984.1 - 0.39 10.2 2.2 20 4.8 0.1 2.7 2 0 0 2 2 2 0 HemY protein N-terminus Radical_SAM PF04055.16 CCF53985.1 - 1.8e-15 57.4 0.1 5.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCF53985.1 - 5.8e-11 42.2 0.0 2e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCF53985.1 - 0.0042 17.2 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GCV_H PF01597.14 CCF53986.1 - 4e-43 145.9 0.1 4.7e-43 145.7 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 CCF53986.1 - 6.8e-05 22.5 0.1 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 CCF53986.1 - 7.1e-05 22.3 0.4 0.00012 21.6 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCF53986.1 - 0.064 12.9 1.0 5.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Mito_carr PF00153.22 CCF53988.1 - 1.3e-43 146.5 0.3 1.6e-16 59.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF498 PF04430.9 CCF53989.1 - 2.5e-21 75.3 0.0 4.7e-21 74.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) zf-H2C2_2 PF13465.1 CCF53990.1 - 1.5e-23 81.8 42.3 1.1e-08 34.9 1.2 7.3 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCF53990.1 - 5.1e-18 64.2 42.0 1.2e-05 25.3 0.5 9.4 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCF53990.1 - 1.2e-06 28.5 4.0 0.00049 20.1 0.1 4.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCF53990.1 - 2.1e-05 24.5 56.6 0.0063 16.7 0.5 9.8 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCF53990.1 - 2.8e-05 23.8 26.7 0.00097 18.9 0.4 6.3 7 0 0 7 7 7 3 C2H2-type zinc finger Biotin_lipoyl PF00364.17 CCF53991.1 - 1.5e-21 75.8 1.3 3.5e-21 74.5 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CCF53991.1 - 2.7e-08 33.3 3.5 1.8e-05 24.3 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like E3_binding PF02817.12 CCF53991.1 - 5.4e-08 32.3 0.0 5.4e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain HlyD_2 PF12700.2 CCF53991.1 - 0.07 12.2 0.6 6.7 5.7 0.3 2.1 1 1 1 2 2 2 0 HlyD family secretion protein RNA_polI_A34 PF08208.6 CCF53992.1 - 5.9e-08 32.6 11.5 0.0076 15.9 7.3 2.5 2 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 adh_short PF00106.20 CCF53993.1 - 2.1e-10 40.7 10.2 5.2e-05 23.2 0.7 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCF53993.1 - 4.2e-07 29.8 4.0 0.00024 20.8 0.1 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 CCF53993.1 - 0.00019 21.2 1.9 0.53 10.0 0.8 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 2OG-FeII_Oxy_2 PF13532.1 CCF53995.1 - 7.8e-12 45.4 2.0 8.8e-12 45.2 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-C2HC5 PF06221.8 CCF53995.1 - 1.3 8.7 8.9 0.24 11.1 1.6 2.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type PUF PF00806.14 CCF53996.1 - 1.8e-23 80.6 0.0 1.2e-05 24.4 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 CCF53996.1 - 5.2e-23 80.4 0.0 1e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF53996.1 - 2.8e-14 52.6 0.0 8.4e-08 31.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF53996.1 - 1.3e-12 47.5 0.0 1e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF PF08080.7 CCF53996.1 - 0.00016 21.0 0.5 0.0004 19.8 0.3 1.7 1 0 0 1 1 1 1 RNPHF zinc finger Nup35_RRM_2 PF14605.1 CCF53996.1 - 0.18 11.6 0.0 4 7.2 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 CCF53997.1 - 2.7e-06 27.0 2.2 2.7e-06 27.0 1.5 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-RanBP PF00641.13 CCF53997.1 - 0.24 10.5 0.2 0.24 10.5 0.1 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Lipase_3 PF01764.20 CCF53999.1 - 5.5e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CCF53999.1 - 0.00038 20.2 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family GIT_SHD PF08518.6 CCF53999.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT UPF0227 PF05728.7 CCF53999.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SNARE_assoc PF09335.6 CCF54000.1 - 1.5e-16 60.6 9.2 1.5e-16 60.6 6.3 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein Pkinase PF00069.20 CCF54001.1 - 8.1e-35 120.2 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54001.1 - 2.3e-13 49.8 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_phi PF04931.8 CCF54002.1 - 1.5e-46 158.6 51.5 4.9e-44 150.3 35.7 3.3 1 1 0 1 1 1 1 DNA polymerase phi Rhodanese PF00581.15 CCF54003.1 - 5.4e-12 46.0 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Trypan_PARP PF05887.6 CCF54004.1 - 0.0015 18.3 0.3 0.028 14.2 0.7 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.8 CCF54004.1 - 0.043 12.5 8.2 0.055 12.1 5.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF2360 PF10152.4 CCF54004.1 - 0.86 9.8 3.5 1.3 9.3 2.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 CCF54004.1 - 1.1 8.5 14.6 1.4 8.2 10.2 1.2 1 0 0 1 1 1 0 Vta1 like FAP PF07174.6 CCF54004.1 - 1.1 8.4 18.1 1.7 7.8 12.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Acetyltransf_1 PF00583.19 CCF54005.1 - 1.3e-13 50.7 0.1 2.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HhH-GPD PF00730.20 CCF54005.1 - 9.2e-12 45.2 0.0 9.5e-11 41.9 0.0 2.5 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein Acetyltransf_7 PF13508.1 CCF54005.1 - 2e-07 31.0 0.1 3.9e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF54005.1 - 3.1e-06 26.8 0.0 7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCF54005.1 - 8.5e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF54005.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HHH_2 PF12826.2 CCF54005.1 - 0.061 13.2 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Acetyltransf_9 PF13527.1 CCF54005.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NPR2 PF06218.6 CCF54006.1 - 1.1e-100 337.4 0.0 5.7e-44 150.4 0.0 4.1 3 1 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.8 CCF54006.1 - 0.019 13.5 0.0 3.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M28 PF04389.12 CCF54007.1 - 1.3e-33 116.2 0.0 1.9e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Homeobox PF00046.24 CCF54008.1 - 3.7e-13 48.8 0.6 9.6e-13 47.5 0.4 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCF54008.1 - 0.00013 21.6 0.0 0.00041 20.0 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Sec63 PF02889.11 CCF54009.1 - 5.2e-84 282.1 0.0 1e-83 281.1 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CCF54009.1 - 2.3e-41 141.0 2.4 1.9e-29 102.3 0.1 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CCF54009.1 - 1.2e-11 44.8 0.1 8e-09 35.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCF54009.1 - 4e-07 29.7 0.0 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCF54009.1 - 9.3e-06 25.8 0.7 0.012 15.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CCF54009.1 - 9.6e-06 24.6 0.5 0.011 14.6 0.0 4.1 4 0 0 4 4 4 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 CCF54009.1 - 4.5e-05 22.9 0.7 0.5 9.7 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein SNF2_N PF00176.18 CCF54009.1 - 0.00089 18.1 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_29 PF13555.1 CCF54009.1 - 0.0016 17.9 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CCF54009.1 - 0.0023 17.4 0.3 0.25 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain PhoH PF02562.11 CCF54009.1 - 0.0052 16.0 0.4 2 7.6 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Helicase_RecD PF05127.9 CCF54009.1 - 0.015 14.9 0.6 3.1 7.4 0.0 3.2 2 1 0 2 2 2 0 Helicase AAA_23 PF13476.1 CCF54009.1 - 0.18 12.0 1.4 4.3 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CCF54009.1 - 0.46 11.3 1.5 12 6.7 0.2 3.6 3 1 0 3 3 3 0 AAA domain ApbA_C PF08546.6 CCF54010.1 - 2.6e-25 88.8 0.0 3.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCF54010.1 - 1.1e-17 63.8 0.0 1.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Synaptobrevin PF00957.16 CCF54011.1 - 3.9e-26 90.4 0.0 5.4e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CCF54011.1 - 1.7e-21 75.5 0.0 2.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain AMP-binding PF00501.23 CCF54012.1 - 5e-48 163.5 0.0 6.9e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF54012.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Tom37_C PF11801.3 CCF54014.1 - 2.5e-07 30.7 0.0 0.00033 20.5 0.0 2.4 2 0 0 2 2 2 2 Tom37 C-terminal domain Lactonase PF10282.4 CCF54014.1 - 4e-07 29.4 0.1 3.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Tom37 PF10568.4 CCF54014.1 - 0.0084 16.3 0.1 0.03 14.5 0.0 2.0 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein tRNA_Me_trans PF03054.11 CCF54015.1 - 1.2e-107 359.5 0.0 1.4e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 CCF54015.1 - 0.00035 19.5 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 CCF54015.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase SAP PF02037.22 CCF54015.1 - 0.086 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 SAP domain CENP-C_C PF11699.3 CCF54016.1 - 1.8e-29 101.5 0.0 3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 CCF54016.1 - 0.00099 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain PTCB-BRCT PF12738.2 CCF54017.1 - 4e-35 119.4 0.0 1.8e-14 53.3 0.0 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 CCF54017.1 - 3.1e-25 88.1 0.0 5.2e-11 42.5 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain CLTH PF10607.4 CCF54019.1 - 8.7e-23 80.6 0.0 1.4e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCF54019.1 - 0.0081 15.9 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 LisH WD40 PF00400.27 CCF54020.1 - 2.3e-24 84.3 12.1 6.5e-08 32.1 0.1 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.3 CCF54020.1 - 0.0044 15.2 6.5 0.016 13.4 0.5 2.3 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Vfa1 PF08432.5 CCF54020.1 - 2.1 8.3 14.0 0.71 9.8 7.5 1.8 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Brix PF04427.13 CCF54021.1 - 9.3e-27 93.9 0.0 2e-26 92.8 0.0 1.5 1 1 0 1 1 1 1 Brix domain SGT1 PF07093.6 CCF54021.1 - 0.0051 15.2 8.7 0.0053 15.1 6.0 1.1 1 0 0 1 1 1 1 SGT1 protein Daxx PF03344.10 CCF54021.1 - 0.052 12.0 24.6 0.083 11.3 17.0 1.2 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 CCF54021.1 - 0.22 10.5 27.7 0.32 10.0 19.2 1.2 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.4 CCF54021.1 - 0.33 9.6 36.5 0.66 8.6 25.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 CCF54021.1 - 0.44 9.2 22.8 0.65 8.6 15.7 1.3 1 1 0 1 1 1 0 Paf1 CENP-T PF15511.1 CCF54021.1 - 2 7.5 23.7 3.7 6.6 16.4 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PPP4R2 PF09184.6 CCF54021.1 - 5 6.5 23.4 9.2 5.7 16.2 1.4 1 0 0 1 1 1 0 PPP4R2 Mpp10 PF04006.7 CCF54021.1 - 7.1 4.8 28.7 9.3 4.4 19.9 1.3 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.7 CCF54021.1 - 7.6 5.7 29.9 14 4.8 20.7 1.5 1 0 0 1 1 1 0 SDA1 Peptidase_S28 PF05577.7 CCF54022.1 - 2.6e-39 135.0 0.0 2.2e-34 118.8 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CCF54022.1 - 0.025 14.4 0.1 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ras PF00071.17 CCF54023.1 - 3.5e-53 179.2 0.0 4.1e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF54023.1 - 9.9e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF54023.1 - 1.3e-06 27.8 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-C3HC4_3 PF13920.1 CCF54024.1 - 0.0011 18.6 8.4 0.0019 17.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF54024.1 - 0.022 14.7 12.0 0.035 14.1 8.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF54024.1 - 0.029 14.0 11.3 0.047 13.3 7.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pex2_Pex12 PF04757.9 CCF54025.1 - 2.2e-49 167.9 7.2 2.8e-49 167.6 5.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CCF54025.1 - 9.6e-06 25.5 1.6 1.6e-05 24.8 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCF54025.1 - 0.00016 21.2 0.6 0.00026 20.6 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF54025.1 - 0.00059 19.6 3.1 0.0024 17.6 2.2 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCF54025.1 - 0.019 14.5 0.9 0.031 13.9 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCF54025.1 - 0.025 14.4 3.9 0.045 13.6 2.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UCH PF00443.24 CCF54026.1 - 1.8e-44 151.8 0.0 3.3e-44 151.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCF54026.1 - 1e-23 83.2 12.5 1.2e-18 66.9 1.2 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CCF54026.1 - 1.6e-15 57.3 0.0 2.4e-14 53.4 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CCF54026.1 - 7.1e-15 54.3 1.0 9.5e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain Fungal_trans PF04082.13 CCF54028.1 - 3.2e-10 39.3 0.9 7.4e-10 38.1 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF54028.1 - 3.8e-06 26.7 9.2 7.3e-06 25.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flg_hook PF02120.11 CCF54028.1 - 0.2 11.3 3.3 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Met_10 PF02475.11 CCF54029.1 - 2.5e-49 167.5 0.0 1.8e-48 164.7 0.0 2.2 1 1 0 1 1 1 1 Met-10+ like-protein Gag_p17 PF00540.13 CCF54029.1 - 0.051 13.3 1.1 0.12 12.1 0.0 2.1 3 0 0 3 3 3 0 gag gene protein p17 (matrix protein) PIG-L PF02585.12 CCF54030.1 - 2.9e-22 79.5 0.0 4.2e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LIF_OSM PF01291.12 CCF54031.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 LIF / OSM family Chorismate_bind PF00425.13 CCF54032.1 - 2.4e-86 289.2 0.0 3.4e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCF54032.1 - 5.9e-29 100.8 0.0 2.5e-28 98.8 0.0 2.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.3 CCF54033.1 - 5.9e-62 209.1 2.5 5.9e-62 209.1 1.7 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CCF54033.1 - 1.2e-30 104.8 1.0 3.7e-14 52.1 0.1 2.5 2 0 0 2 2 2 2 Surp module CTI PF06934.6 CCF54033.1 - 0.036 12.3 0.1 0.065 11.4 0.0 1.3 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DUF4588 PF15251.1 CCF54034.1 - 6.5 6.6 10.1 1.6 8.6 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) AP_endonuc_2 PF01261.19 CCF54035.1 - 7.1e-28 97.3 0.0 1.1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DTHCT PF08070.6 CCF54035.1 - 6.7 7.4 14.8 0.36 11.4 1.0 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region WD40 PF00400.27 CCF54037.1 - 1.7e-16 59.3 10.9 5.4e-06 26.0 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3186 PF11382.3 CCF54037.1 - 0.023 13.8 1.1 0.04 13.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Asn_synthase PF00733.16 CCF54038.1 - 1.6e-67 227.6 0.1 3.5e-67 226.5 0.1 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCF54038.1 - 3.1e-38 130.3 0.0 4.8e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCF54038.1 - 4.2e-30 104.4 0.0 9.5e-30 103.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CCF54038.1 - 4e-08 32.3 0.0 5e-05 22.1 0.0 2.7 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 CCF54038.1 - 2.1e-06 27.0 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 CCF54038.1 - 0.013 14.4 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD synthase DUF1776 PF08643.5 CCF54039.1 - 8.2e-06 25.1 0.0 0.069 12.2 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.20 CCF54039.1 - 0.0053 16.6 0.0 0.94 9.3 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase DEAD PF00270.24 CCF54040.1 - 1.4e-46 158.0 0.0 3.7e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54040.1 - 8.1e-27 92.9 0.0 1.8e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF54040.1 - 0.00028 20.7 0.0 0.0021 17.9 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCF54040.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain BATS PF06968.8 CCF54041.1 - 1.3e-26 92.2 0.0 4.1e-26 90.6 0.0 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CCF54041.1 - 2.3e-13 50.6 0.1 4.3e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Zn_clus PF00172.13 CCF54042.1 - 8.1e-10 38.4 29.4 9.2e-08 31.8 6.1 3.0 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2502 PF10697.4 CCF54043.1 - 0.21 11.7 5.2 0.33 11.0 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) DUF4603 PF15376.1 CCF54043.1 - 0.38 7.8 5.5 0.41 7.7 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF2992 PF11208.3 CCF54043.1 - 7.6 6.4 13.0 11 5.9 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Ribosomal_L10 PF00466.15 CCF54045.1 - 4.6e-16 58.5 0.0 7.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Nucleoplasmin PF03066.10 CCF54045.1 - 0.31 10.5 9.1 0.53 9.7 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCF54045.1 - 1.8 7.7 9.4 2.7 7.1 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 CCF54045.1 - 2.7 7.7 6.9 5.5 6.7 4.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 CCF54045.1 - 2.8 7.5 11.4 5.1 6.7 7.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 CCF54045.1 - 5.5 5.3 11.7 7.3 4.9 8.1 1.1 1 0 0 1 1 1 0 Daxx Family HEAT_2 PF13646.1 CCF54046.1 - 2.7e-29 101.2 4.1 5e-15 55.5 1.0 2.7 2 1 0 2 2 2 2 HEAT repeats HEAT_PBS PF03130.11 CCF54046.1 - 1.1e-17 62.6 1.0 0.0019 18.4 0.0 6.7 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 CCF54046.1 - 9.8e-11 40.8 2.0 0.025 14.6 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CCF54046.1 - 2.5e-10 40.5 1.9 0.19 12.2 0.2 5.3 5 1 1 6 6 6 3 HEAT-like repeat DUF1546 PF07571.8 CCF54046.1 - 0.055 13.5 0.0 1.4 9.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1546) Arm PF00514.18 CCF54046.1 - 0.14 12.0 0.4 24 4.9 0.0 3.6 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 CCF54046.1 - 0.34 10.9 1.9 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion CLTH PF10607.4 CCF54047.1 - 5.2e-32 110.5 0.0 6.9e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCF54047.1 - 4.3e-10 38.9 0.1 1.3e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 LisH DWNN PF08783.6 CCF54048.1 - 3.6e-34 116.5 0.0 6.8e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.18 CCF54048.1 - 2.7e-06 27.0 1.6 5.5e-06 26.0 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CCF54048.1 - 1.8e-05 24.0 3.2 4.7e-05 22.7 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 CCF54048.1 - 9.7e-05 22.2 0.9 0.0097 15.8 0.0 2.9 2 1 1 3 3 2 1 U-box domain zf-C3HC4_2 PF13923.1 CCF54048.1 - 0.0011 18.9 13.5 0.0011 18.9 9.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Sds3 PF08598.6 CCF54048.1 - 0.0046 16.5 0.7 0.0092 15.5 0.5 1.6 1 0 0 1 1 1 1 Sds3-like zf-CCHC_5 PF14787.1 CCF54048.1 - 0.014 14.8 0.9 0.042 13.3 0.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4163 PF13739.1 CCF54048.1 - 0.027 15.2 1.0 0.057 14.1 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) Frigida PF07899.6 CCF54048.1 - 0.066 11.9 2.5 0.11 11.1 1.7 1.3 1 0 0 1 1 1 0 Frigida-like protein Borrelia_P83 PF05262.6 CCF54048.1 - 0.084 11.1 2.6 0.12 10.5 1.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C3HC4_3 PF13920.1 CCF54048.1 - 0.13 11.9 11.4 0.35 10.5 7.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF54048.1 - 0.26 11.1 12.4 0.54 10.1 8.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CCF54048.1 - 1.3 8.7 15.0 2.5 7.8 10.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCF54048.1 - 4.8 7.1 13.5 12 5.9 9.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CCF54048.1 - 6 6.7 8.9 1.3 8.8 2.7 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Plasmodium_Vir PF05795.6 CCF54048.1 - 8.7 5.4 8.5 16 4.5 5.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LCAT PF02450.10 CCF54049.1 - 2.7e-87 293.2 1.3 1.2e-86 291.1 0.9 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase MOR2-PAG1_N PF14222.1 CCF54050.1 - 6.1e-158 526.9 0.4 1.2e-157 525.9 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CCF54050.1 - 9.7e-55 186.1 0.3 3.6e-28 99.0 0.1 3.1 3 0 0 3 3 3 2 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CCF54050.1 - 2.4e-27 95.0 2.3 8.9e-13 46.7 0.0 4.1 3 1 1 4 4 4 4 Cell morphogenesis central region Acid_PPase PF12689.2 CCF54051.1 - 1.5e-58 197.1 0.0 1.8e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 CCF54051.1 - 0.00018 21.7 0.2 0.045 13.9 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Pex2_Pex12 PF04757.9 CCF54052.1 - 5.7e-38 130.6 7.1 8.3e-38 130.0 5.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 CCF54052.1 - 0.00034 20.2 0.8 0.0021 17.6 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF54052.1 - 0.003 17.3 2.2 0.36 10.6 0.4 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 CCF54052.1 - 0.044 13.8 2.6 0.11 12.5 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCF54052.1 - 0.074 13.1 0.1 18 5.5 0.0 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger Fer2 PF00111.22 CCF54052.1 - 0.087 12.5 0.7 0.22 11.2 0.5 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_5 PF14634.1 CCF54052.1 - 2.4 7.9 5.7 2.3 8.0 1.7 2.2 2 1 0 2 2 2 0 zinc-RING finger domain PBP PF01161.15 CCF54053.1 - 2.1e-12 47.1 0.0 3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DnaJ PF00226.26 CCF54054.1 - 2.7e-19 68.6 0.9 5.3e-19 67.7 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain RIX1 PF08167.7 CCF54055.1 - 1.6e-10 40.9 5.0 2.1e-10 40.5 1.3 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sec10 PF07393.6 CCF54056.1 - 1.6e-282 938.9 0.0 2e-282 938.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 CTD_bind PF04818.8 CCF54056.1 - 0.11 12.7 0.2 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Glyco_hydro_16 PF00722.16 CCF54057.1 - 4.5e-34 117.3 4.6 6.5e-34 116.8 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.6 CCF54057.1 - 0.0024 17.7 1.3 0.0042 16.9 0.9 1.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_3 PF13385.1 CCF54057.1 - 0.0032 17.7 6.0 0.0061 16.8 4.1 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Chitin_bind_1 PF00187.14 CCF54057.1 - 0.0068 16.3 13.5 0.013 15.4 9.4 1.5 1 0 0 1 1 1 1 Chitin recognition protein Peptidase_C37 PF05416.7 CCF54058.1 - 0.033 12.4 0.1 0.062 11.5 0.1 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase TPR_11 PF13414.1 CCF54059.1 - 1.1e-26 92.2 13.1 4.2e-07 29.5 0.1 7.3 6 1 1 7 7 7 6 TPR repeat TPR_2 PF07719.12 CCF54059.1 - 2.3e-17 61.4 21.7 0.021 14.6 0.1 10.6 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCF54059.1 - 6e-17 61.8 25.0 0.00061 20.4 1.0 7.9 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCF54059.1 - 6.2e-15 53.7 4.2 0.27 11.0 0.0 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF54059.1 - 2.6e-14 53.3 14.6 5e-06 26.7 1.2 6.9 5 1 1 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCF54059.1 - 1.9e-11 43.0 13.6 0.015 14.8 0.1 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCF54059.1 - 4.4e-11 42.5 23.8 0.00021 21.1 0.4 7.0 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCF54059.1 - 3.4e-10 39.6 26.1 0.00022 21.5 0.3 10.9 9 3 3 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCF54059.1 - 8.7e-10 38.0 0.2 0.39 11.0 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCF54059.1 - 2.5e-08 33.8 9.3 1.6 9.3 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCF54059.1 - 4.3e-07 29.2 3.6 0.0012 17.9 0.5 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CCF54059.1 - 5.2e-06 26.5 6.8 0.032 14.3 0.8 4.6 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCF54059.1 - 0.00016 21.4 9.1 0.0076 16.0 0.1 4.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCF54059.1 - 0.00059 19.8 10.4 0.38 10.9 0.0 5.5 4 1 1 6 6 5 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CCF54059.1 - 0.0026 17.9 0.2 2 8.6 0.1 2.6 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_7 PF13176.1 CCF54059.1 - 0.0041 16.8 14.2 12 6.0 0.1 7.6 9 0 0 9 9 6 0 Tetratricopeptide repeat NARP1 PF12569.3 CCF54059.1 - 0.017 13.9 13.4 0.024 13.3 0.9 3.7 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 Vps39_1 PF10366.4 CCF54059.1 - 0.074 13.0 0.1 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Nup88 PF10168.4 CCF54060.1 - 2.7e-17 61.9 5.5 1.3e-10 39.7 0.0 2.9 3 1 0 3 3 3 2 Nuclear pore component 4HBT_3 PF13622.1 CCF54061.1 - 1.8e-39 136.0 0.1 3.2e-39 135.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CCF54061.1 - 6.8e-29 100.1 0.0 3.1e-22 78.6 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase Sec1 PF00995.18 CCF54062.1 - 2.7e-153 511.6 0.0 3.1e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3446 PF11928.3 CCF54063.1 - 0.67 10.1 14.1 3.2 8.0 1.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Pkinase PF00069.20 CCF54064.1 - 6.7e-41 140.1 0.0 8.1e-26 90.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54064.1 - 1.1e-16 60.6 0.0 8.3e-16 57.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCF54064.1 - 0.22 10.5 0.0 0.45 9.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 CCF54065.1 - 3.9e-44 149.4 0.0 4.4e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Syntaxin-18_N PF10496.4 CCF54066.1 - 1.4e-14 53.6 0.0 1.6e-13 50.2 0.0 2.6 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 CCF54066.1 - 0.017 14.7 1.9 0.017 14.7 1.3 2.1 2 0 0 2 2 2 0 SNARE domain Glyco_transf_22 PF03901.12 CCF54067.1 - 5.2e-35 121.2 10.8 7e-35 120.8 7.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XAP5 PF04921.9 CCF54068.1 - 1.2e-95 319.5 7.4 1.2e-95 319.5 5.1 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator Cut8_N PF14482.1 CCF54068.1 - 1 9.3 6.3 0.73 9.8 2.1 2.3 1 1 1 2 2 2 0 Cut8 proteasome-binding domain ACT_7 PF13840.1 CCF54069.1 - 4.7e-12 45.2 0.0 8.8e-12 44.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain Sld5 PF05916.6 CCF54072.1 - 5.5e-09 36.2 0.0 8.3e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein Herpes_UL25 PF01499.11 CCF54072.1 - 0.032 12.5 0.0 0.04 12.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Pex19 PF04614.7 CCF54072.1 - 0.12 12.0 0.5 0.16 11.5 0.3 1.1 1 0 0 1 1 1 0 Pex19 protein family AA_permease PF00324.16 CCF54073.1 - 2.4e-132 441.6 40.4 2.8e-132 441.4 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCF54073.1 - 3.1e-43 147.9 46.5 4.2e-43 147.4 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease Phytochelatin_C PF09328.5 CCF54074.1 - 0.067 12.6 1.6 0.11 11.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Flavin_Reduct PF01613.13 CCF54075.1 - 9.2e-20 71.0 0.1 1.3e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Methyltransf_12 PF08242.7 CCF54076.1 - 4.8e-17 62.2 0.0 1.1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF54076.1 - 8.2e-16 58.1 2.5 3.8e-15 55.9 1.7 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54076.1 - 2.9e-14 52.9 0.0 4.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54076.1 - 4.3e-14 52.7 0.0 8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54076.1 - 9.1e-13 48.7 0.0 2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF54076.1 - 1.2e-08 35.2 0.0 2.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF54076.1 - 8.4e-08 31.6 0.0 1.3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CCF54076.1 - 3.1e-06 26.6 0.1 6.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 CCF54076.1 - 6.5e-06 25.2 0.0 0.00025 20.0 0.0 2.1 1 1 0 1 1 1 1 DREV methyltransferase DUF938 PF06080.7 CCF54076.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Cons_hypoth95 PF03602.10 CCF54076.1 - 0.0028 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 CCF54076.1 - 0.0031 16.5 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 CCF54076.1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Polysacc_synt_2 PF02719.10 CCF54076.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NPV_P10 PF05531.7 CCF54076.1 - 0.012 15.8 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CmcI PF04989.7 CCF54076.1 - 0.047 12.9 0.3 0.09 12.0 0.2 1.5 1 0 0 1 1 1 0 Cephalosporin hydroxylase Zip PF02535.17 CCF54076.1 - 0.37 9.7 9.0 0.48 9.3 6.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CCF54076.1 - 0.99 8.7 16.5 2.2 7.6 11.4 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFCD_C PF12612.3 CCF54078.1 - 2.2e-34 118.5 0.2 4.9e-32 110.9 0.0 4.2 5 1 0 5 5 5 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CCF54078.1 - 3.9e-05 23.8 15.7 0.062 13.5 0.0 6.8 5 1 2 7 7 7 2 HEAT repeats DUF2435 PF10363.4 CCF54078.1 - 0.0015 18.3 0.1 0.2 11.5 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CCF54078.1 - 0.0064 16.3 0.6 3 7.6 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCF54078.1 - 0.0082 16.1 0.0 0.0082 16.1 0.0 8.1 9 0 0 9 9 9 1 HEAT repeat Ipi1_N PF12333.3 CCF54078.1 - 0.0097 15.8 0.1 4.9 7.1 0.0 4.2 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT_PBS PF03130.11 CCF54078.1 - 0.18 12.3 0.0 0.18 12.3 0.0 5.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CCF54078.1 - 0.23 12.0 21.1 1.4 9.5 0.0 7.3 6 1 1 7 7 7 0 HEAT-like repeat Lipase_3 PF01764.20 CCF54079.1 - 1.3e-16 60.4 0.0 4.1e-16 58.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) SLX9 PF15341.1 CCF54080.1 - 2.3e-18 66.7 16.5 2.3e-18 66.7 11.4 1.8 2 1 0 2 2 1 1 Ribosome biogenesis protein SLX9 Nop14 PF04147.7 CCF54080.1 - 0.0019 16.2 13.2 0.002 16.1 9.1 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 CCF54080.1 - 0.0094 14.6 8.5 0.011 14.4 5.9 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SGT1 PF07093.6 CCF54080.1 - 0.01 14.2 10.2 0.011 14.1 7.1 1.1 1 0 0 1 1 1 0 SGT1 protein Sigma70_ner PF04546.8 CCF54080.1 - 0.014 15.0 12.4 0.021 14.4 8.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Packaging_FI PF14000.1 CCF54080.1 - 0.027 14.6 6.8 0.033 14.3 3.9 1.8 2 0 0 2 2 2 0 DNA packaging protein FI CENP-B_dimeris PF09026.5 CCF54080.1 - 0.036 14.2 10.9 0.062 13.5 7.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TP_methylase PF00590.15 CCF54080.1 - 0.048 13.3 0.6 0.078 12.6 0.4 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4611 PF15387.1 CCF54080.1 - 0.089 12.9 10.9 0.19 11.8 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SDA1 PF05285.7 CCF54080.1 - 0.094 11.9 17.1 0.16 11.2 11.9 1.3 1 0 0 1 1 1 0 SDA1 MAPEG PF01124.13 CCF54080.1 - 0.18 11.4 0.1 0.49 10.0 0.1 1.9 1 1 0 1 1 1 0 MAPEG family Phage_GPO PF05929.6 CCF54080.1 - 0.23 10.6 7.6 0.27 10.4 4.9 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase BTV_NS2 PF04514.7 CCF54080.1 - 0.25 10.1 8.8 0.29 9.9 6.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 eIF-3c_N PF05470.7 CCF54080.1 - 1.2 7.1 12.2 1.6 6.7 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 CCF54080.1 - 3 5.7 21.5 2.8 5.8 14.4 1.3 1 1 0 1 1 1 0 CDC45-like protein CDC27 PF09507.5 CCF54080.1 - 4.6 6.3 20.7 6.6 5.8 14.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop25 PF09805.4 CCF54080.1 - 5.2 7.1 16.4 10 6.1 11.3 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2890 PF11081.3 CCF54080.1 - 5.7 6.9 24.0 0.017 15.1 8.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Afi1 PF07792.7 CCF54080.1 - 6.6 6.7 14.0 23 4.9 9.7 1.9 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking GCIP PF13324.1 CCF54080.1 - 9.9 5.2 10.9 16 4.6 7.5 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting p450 PF00067.17 CCF54081.1 - 1.4e-55 188.7 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mannosyl_trans PF05007.8 CCF54082.1 - 3.3e-61 207.1 15.9 1.9e-57 194.8 10.5 2.4 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) UPF0061 PF02696.9 CCF54083.1 - 1.8e-84 283.8 0.0 3.1e-84 283.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Cupin_8 PF13621.1 CCF54084.1 - 7.9e-21 74.6 0.4 1.1e-20 74.2 0.3 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCF54084.1 - 7.5e-15 55.1 0.1 1.5e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 CCF54084.1 - 0.067 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Peptidase_C48 PF02902.14 CCF54085.1 - 4.5e-36 124.5 0.1 6.9e-33 114.0 0.0 2.6 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain SGT1 PF07093.6 CCF54086.1 - 4.1e-141 471.2 21.7 2.6e-138 462.0 15.1 2.1 1 1 0 1 1 1 1 SGT1 protein PG_binding_2 PF08823.6 CCF54086.1 - 0.077 13.1 0.0 0.077 13.1 0.0 2.4 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DIL PF01843.14 CCF54087.1 - 3.2e-27 94.4 0.2 7.5e-27 93.2 0.2 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 CCF54087.1 - 3.3e-16 59.3 0.0 9.7e-16 57.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCF54087.1 - 3.9e-14 51.6 1.1 8.4e-07 28.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CCF54087.1 - 2.1e-11 44.0 0.1 0.0043 17.5 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF54087.1 - 3e-11 42.4 0.0 0.00052 19.9 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCF54087.1 - 2.4e-09 37.1 0.4 0.00063 19.8 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) eIF-3c_N PF05470.7 CCF54087.1 - 0.095 10.7 6.0 0.15 10.1 4.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MerC PF03203.9 CCF54088.1 - 2 8.8 8.8 0.17 12.2 2.0 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein MIT PF04212.13 CCF54089.1 - 7.8e-05 22.4 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SUR7 PF06687.7 CCF54090.1 - 2.4e-30 105.6 0.3 2.8e-30 105.4 0.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCF54090.1 - 6.5e-05 22.6 5.6 6.5e-05 22.6 3.9 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CCF54090.1 - 0.0071 16.0 0.7 0.0071 16.0 0.5 2.0 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin family SH3BGR PF04908.10 CCF54090.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF4064 PF13273.1 CCF54090.1 - 0.63 10.1 5.5 0.76 9.9 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Yip1 PF04893.12 CCF54090.1 - 1.1 8.7 13.9 0.23 10.9 6.9 1.7 2 0 0 2 2 2 0 Yip1 domain VIT1 PF01988.14 CCF54090.1 - 4.7 6.6 9.9 6.8 6.1 2.2 3.0 3 0 0 3 3 3 0 VIT family CorA PF01544.13 CCF54091.1 - 2e-45 155.0 0.3 3e-45 154.4 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 CCF54091.1 - 0.071 13.4 0.2 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 ACT domain Baculo_PEP_C PF04513.7 CCF54091.1 - 0.076 12.8 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 CCF54091.1 - 0.16 11.6 0.3 1.5 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) MOSC_N PF03476.11 CCF54092.1 - 3.4e-18 65.4 0.1 2.1e-17 62.9 0.0 2.3 2 1 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CCF54092.1 - 1.3e-11 44.1 0.0 2.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain AMP-binding PF00501.23 CCF54093.1 - 7.4e-83 278.2 0.0 1.2e-82 277.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ADH_zinc_N PF00107.21 CCF54093.1 - 2e-17 62.9 0.4 2e-17 62.9 0.3 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AMP-binding_C PF13193.1 CCF54093.1 - 1.2e-16 61.4 0.2 2.8e-16 60.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 CCF54093.1 - 0.00071 19.3 0.7 0.029 14.1 0.0 3.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Prp31_C PF09785.4 CCF54094.1 - 4.6e-41 140.1 3.5 1.1e-40 138.9 2.4 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 CCF54094.1 - 1.2e-39 134.9 0.4 2e-39 134.2 0.2 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCF54094.1 - 5.9e-20 70.8 0.1 1e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NAM-associated PF14303.1 CCF54094.1 - 0.41 10.9 4.2 0.95 9.7 2.9 1.6 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ada3 PF10198.4 CCF54095.1 - 0.088 12.5 2.2 0.13 12.0 1.2 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF4398 PF14346.1 CCF54095.1 - 0.67 10.0 7.6 0.93 9.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) MCM PF00493.18 CCF54096.1 - 1.5e-137 457.8 0.4 2.2e-137 457.2 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCF54096.1 - 5.1e-21 75.3 0.4 2.4e-20 73.2 0.0 2.4 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCF54096.1 - 1.1e-07 31.2 0.0 4.6e-07 29.1 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCF54096.1 - 0.0014 18.2 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCF54096.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CCF54096.1 - 0.02 14.6 0.0 0.055 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.9 CCF54096.1 - 0.024 14.7 0.0 0.099 12.7 0.0 2.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Ceramidase_alk PF04734.8 CCF54097.1 - 1.4e-217 723.8 0.0 1.1e-216 720.8 0.0 2.0 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase ATP-grasp_2 PF08442.5 CCF54098.1 - 3.3e-73 245.3 1.1 4e-73 245.1 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 CCF54098.1 - 6e-22 77.8 0.9 1.3e-21 76.7 0.4 1.8 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 CCF54098.1 - 4.6e-11 42.3 0.7 7.6e-11 41.6 0.1 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CCF54098.1 - 0.00017 21.1 0.5 0.00048 19.7 0.1 2.0 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CCF54098.1 - 0.00073 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CCF54098.1 - 0.0048 16.2 0.2 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain PASTA PF03793.14 CCF54098.1 - 0.17 11.5 0.5 0.64 9.7 0.1 2.2 2 0 0 2 2 2 0 PASTA domain Rrp15p PF07890.7 CCF54099.1 - 2.2e-32 111.8 6.0 2.2e-32 111.8 4.1 2.3 2 1 0 2 2 2 1 Rrp15p PBP1_TM PF14812.1 CCF54099.1 - 5.3 7.4 19.8 1.6 9.1 4.4 3.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PLDc PF00614.17 CCF54100.1 - 3.1e-15 55.3 0.1 5.6e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCF54100.1 - 3.3e-12 46.2 0.2 1.2e-07 31.5 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PX PF00787.19 CCF54100.1 - 3.8e-10 39.5 0.0 9.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 PX domain UQ_con PF00179.21 CCF54101.1 - 4.6e-39 133.0 0.0 5e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCF54101.1 - 0.00037 20.3 0.1 0.00043 20.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Bac_rhodopsin PF01036.13 CCF54102.1 - 3.3e-44 150.8 16.2 4.1e-44 150.5 11.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ResIII PF04851.10 CCF54102.1 - 0.034 13.9 0.2 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arteri_Gl PF00951.13 CCF54102.1 - 1.1 8.8 7.7 0.091 12.3 1.0 2.0 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein Hydrolase PF00702.21 CCF54103.1 - 4.3e-23 82.8 0.0 4e-22 79.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCF54103.1 - 1.9e-21 76.1 0.5 4.9e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CCF54103.1 - 8.3e-19 68.5 0.0 1.6e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCF54103.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCF54103.1 - 0.014 14.9 0.0 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF54103.1 - 0.022 14.1 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus S6PP PF05116.8 CCF54103.1 - 0.074 12.3 0.0 1.1 8.4 0.0 2.5 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DASH_Dad4 PF08650.5 CCF54104.1 - 9.8e-18 63.8 3.2 1.2e-17 63.6 2.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 MFS_1 PF07690.11 CCF54105.1 - 1.3e-31 109.6 21.7 1.3e-31 109.6 15.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2416 PF10315.4 CCF54105.1 - 0.024 14.8 0.3 0.062 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) EXS PF03124.9 CCF54105.1 - 0.031 13.3 3.2 0.11 11.4 2.2 2.1 1 1 0 1 1 1 0 EXS family Raffinose_syn PF05691.7 CCF54106.1 - 4.6e-27 93.9 0.4 1.5e-23 82.3 0.4 2.9 2 1 1 3 3 3 2 Raffinose synthase or seed imbibition protein Sip1 UCH PF00443.24 CCF54107.1 - 2.9e-58 197.1 0.0 4.5e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF54107.1 - 1.6e-31 109.8 0.1 6.1e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 CCF54107.1 - 0.13 11.5 0.9 0.43 9.8 0.8 1.6 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Zn_clus PF00172.13 CCF54109.1 - 1.5e-06 28.0 13.6 3.4e-06 26.8 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 CCF54111.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) LtrA PF06772.6 CCF54112.1 - 7.9e-20 71.0 14.2 7.9e-20 71.0 9.8 1.7 1 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) BAF1_ABF1 PF04684.8 CCF54112.1 - 0.61 8.8 1.9 0.9 8.3 1.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF3_N PF09440.5 CCF54114.1 - 7.2e-46 155.6 0.3 1.4e-45 154.7 0.2 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CCF54114.1 - 3.4e-09 36.9 0.1 1.9e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 CCF54114.1 - 0.56 10.5 5.1 4.7 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HhH-GPD PF00730.20 CCF54115.1 - 2.1e-11 44.0 0.0 5.4e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NAD_binding_10 PF13460.1 CCF54116.1 - 3.3e-21 76.1 0.0 4.7e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCF54116.1 - 1.7e-14 53.6 0.0 2.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CCF54116.1 - 4.2e-11 42.7 0.2 7.9e-10 38.5 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCF54116.1 - 1.3e-10 40.6 0.0 4e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CCF54116.1 - 1.5e-09 36.9 0.1 9e-09 34.4 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCF54116.1 - 7.4e-08 31.6 0.2 0.00065 18.6 0.2 3.1 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 CCF54116.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 CCF54116.1 - 0.0059 16.5 0.0 0.022 14.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF54116.1 - 0.014 15.0 0.0 0.2 11.3 0.0 2.2 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 CCF54116.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 CCF54116.1 - 0.025 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ferric_reduct PF01794.14 CCF54117.1 - 4.8e-20 71.9 14.9 4.8e-20 71.9 10.3 3.2 3 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCF54117.1 - 5.2e-13 48.7 0.0 1.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCF54117.1 - 1.7e-07 31.3 0.0 2.9e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 CCF54117.1 - 0.011 16.2 0.2 0.11 13.0 0.2 2.2 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Thg1C PF14413.1 CCF54118.1 - 1.9e-43 147.0 0.2 4.4e-43 145.8 0.1 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 CCF54118.1 - 8.8e-41 138.6 0.0 1.3e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase RuvC PF02075.12 CCF54119.1 - 0.06 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC RVT_2 PF07727.9 CCF54120.1 - 9e-30 103.4 0.1 9.8e-30 103.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF54121.1 - 2.6e-07 30.2 0.0 3.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ecl1 PF12855.2 CCF54124.1 - 0.042 13.1 0.9 0.082 12.2 0.6 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 CCF54124.1 - 0.95 9.3 3.9 1.8 8.4 2.7 1.4 1 0 0 1 1 1 0 MYND finger Med3 PF11593.3 CCF54124.1 - 5 6.2 8.2 5.2 6.1 5.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GTP_CH_N PF12471.3 CCF54127.1 - 8.7e-88 293.0 0.0 1.3e-87 292.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 CCF54127.1 - 4.8e-13 48.6 0.0 7.2e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II RVT_2 PF07727.9 CCF54129.1 - 0.02 13.8 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF54130.1 - 1e-20 73.7 0.1 1.2e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.16 CCF54131.1 - 2.3e-79 264.6 0.1 2.7e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCF54131.1 - 2.8e-14 52.7 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCF54131.1 - 5.4e-13 48.6 0.0 5.8e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCF54131.1 - 3.3e-12 45.8 1.3 4.3e-09 35.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCF54131.1 - 3.7e-11 42.5 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCF54131.1 - 3e-09 37.3 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCF54131.1 - 6e-06 26.1 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCF54131.1 - 0.0044 16.4 0.1 0.028 13.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 CCF54131.1 - 0.0068 15.4 0.3 0.019 14.0 0.1 1.6 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CCF54131.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCF54131.1 - 0.13 11.7 0.2 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dfp1_Him1_M PF08630.5 CCF54134.1 - 1.4e-32 112.1 0.0 2.5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCF54134.1 - 2.8e-22 78.1 0.6 5e-22 77.3 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 CCF54134.1 - 0.00024 21.1 0.3 0.00083 19.4 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCF54134.1 - 0.001 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Nbl1_Borealin_N PF10444.4 CCF54135.1 - 2.8e-14 52.2 1.0 4.9e-14 51.4 0.7 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal ECM1 PF05782.6 CCF54135.1 - 0.11 11.1 5.1 0.25 10.0 0.2 2.1 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) Mit_KHE1 PF10173.4 CCF54136.1 - 5.1e-54 182.9 1.1 6.1e-54 182.7 0.2 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF952 PF06108.7 CCF54137.1 - 3.2e-16 58.9 0.0 3.7e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DSHCT PF08148.7 CCF54138.1 - 1.2e-56 190.8 0.2 2.5e-56 189.7 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCF54138.1 - 1.8e-22 79.6 0.0 3.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CCF54138.1 - 9.3e-08 31.5 0.0 7.4e-07 28.5 0.0 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CCF54138.1 - 6.4e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF54138.1 - 0.0037 17.1 0.1 0.045 13.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ferritin_2 PF13668.1 CCF54140.1 - 2.8e-18 66.1 0.2 4.7e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF972 PF06156.8 CCF54142.1 - 0.022 15.0 0.4 0.029 14.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PAS_6 PF08348.6 CCF54142.1 - 0.032 13.8 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 YheO-like PAS domain YopD PF05844.7 CCF54142.1 - 0.053 12.5 0.5 0.06 12.3 0.4 1.0 1 0 0 1 1 1 0 YopD protein CDC37_N PF03234.9 CCF54142.1 - 0.064 13.5 1.2 0.074 13.3 0.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Aldolase_II PF00596.16 CCF54143.1 - 2.1e-43 148.0 0.0 2.7e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PHD PF00628.24 CCF54144.1 - 2.4e-06 27.1 19.1 4.1e-06 26.3 13.2 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CCF54145.1 - 6.2e-21 75.3 0.1 6.2e-21 75.3 0.1 3.8 3 1 0 3 3 3 1 SET domain Zn_clus PF00172.13 CCF54146.1 - 1.1e-06 28.4 10.3 1.9e-06 27.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCF54146.1 - 3.8e-06 25.9 0.1 3.2e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldh_1_N PF00056.18 CCF54147.1 - 1.7e-44 151.0 0.1 2.3e-44 150.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCF54147.1 - 7.5e-43 146.2 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCF54147.1 - 0.00017 20.4 0.0 0.00048 18.9 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 CCF54147.1 - 0.0034 16.4 0.5 0.059 12.4 0.0 2.6 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.19 CCF54147.1 - 0.034 14.4 0.2 0.15 12.3 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF54147.1 - 0.08 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding Ribosomal_L7Ae PF01248.21 CCF54148.1 - 6.7e-21 73.6 0.5 1.1e-20 72.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HTH_Tnp_Tc5 PF03221.11 CCF54149.1 - 6.3e-14 51.5 0.1 1.3e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 CCF54149.1 - 0.003 16.9 0.0 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain EthD PF07110.6 CCF54149.1 - 0.033 15.1 2.1 3.2 8.7 0.0 3.1 2 0 0 2 2 2 0 EthD domain HTH_28 PF13518.1 CCF54149.1 - 0.096 12.7 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.1 CCF54149.1 - 0.17 11.6 0.2 3.2 7.5 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 CCF54149.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CENP-R PF06729.7 CCF54150.1 - 1.3 8.6 9.3 0.36 10.5 2.5 2.8 2 0 0 2 2 2 0 Kinetochore component, CENP-R MAPEG PF01124.13 CCF54151.1 - 2e-12 46.8 2.2 2.4e-12 46.5 1.5 1.1 1 0 0 1 1 1 1 MAPEG family Iso_dh PF00180.15 CCF54152.1 - 1.6e-83 280.5 0.0 2e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase dTMP_synthase PF02593.9 CCF54152.1 - 0.14 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Thymidylate synthase Ribosomal_L13 PF00572.13 CCF54153.1 - 1.2e-46 157.9 0.6 1.4e-46 157.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 PRCC PF10253.4 CCF54154.1 - 0.00011 22.9 0.6 0.00013 22.6 0.4 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF1115 PF06544.7 CCF54157.1 - 4.3e-15 55.5 0.1 8.5e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Peptidase_M43 PF05572.8 CCF54158.1 - 1.5e-14 53.8 0.1 3.4e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 CCF54158.1 - 3.5e-06 27.0 0.4 3.5e-06 27.0 0.3 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 CCF54158.1 - 5.6e-05 23.6 1.6 5.6e-05 23.6 1.1 2.6 2 2 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 CCF54158.1 - 0.00096 18.8 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 CCF54158.1 - 0.001 19.1 1.3 0.0025 17.8 0.9 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 CCF54158.1 - 0.0066 16.0 1.7 0.01 15.3 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 CCF54158.1 - 0.028 14.1 0.2 0.062 13.0 0.2 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family ADH_N PF08240.7 CCF54159.1 - 4.3e-27 94.0 0.1 1.4e-26 92.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF54159.1 - 2.6e-19 69.0 2.8 2.1e-17 62.8 1.9 2.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF54159.1 - 0.0032 18.3 0.0 0.026 15.4 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PrmA PF06325.8 CCF54159.1 - 0.03 13.4 0.8 0.047 12.7 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AlaDh_PNT_C PF01262.16 CCF54159.1 - 0.072 12.6 0.7 0.16 11.5 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer2_BFD PF04324.10 CCF54159.1 - 0.71 9.9 2.9 27 4.9 0.0 2.6 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_C48 PF02902.14 CCF54160.1 - 5.2e-29 101.4 1.8 3.7e-21 75.7 0.7 3.3 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain KH_2 PF07650.12 CCF54160.1 - 0.003 17.0 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 KH domain Aldo_ket_red PF00248.16 CCF54161.1 - 1.5e-54 184.7 0.0 1.9e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA12 PF10443.4 CCF54161.1 - 0.075 11.5 0.0 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein DUF1752 PF08550.5 CCF54162.1 - 2.4e-12 46.2 2.0 4.5e-12 45.3 1.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) HD_3 PF13023.1 CCF54163.1 - 9.9e-40 135.9 0.2 9.9e-40 135.9 0.1 1.8 2 0 0 2 2 2 1 HD domain Methyltransf_28 PF02636.12 CCF54164.1 - 3.6e-36 124.8 0.0 6.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CCF54164.1 - 0.0013 17.8 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CCF54164.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCF54164.1 - 0.022 14.4 0.2 0.066 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CITED PF04487.7 CCF54164.1 - 0.094 12.9 2.0 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 CITED SSP160 PF06933.6 CCF54164.1 - 0.58 8.0 9.4 1.1 7.1 6.5 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CCF54164.1 - 1.5 6.6 14.4 0.028 12.3 2.8 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 CCF54164.1 - 7.9 6.2 13.9 93 2.7 10.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HECT PF00632.20 CCF54165.1 - 1.2e-91 307.1 0.0 2e-91 306.4 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arg_repressor_C PF02863.13 CCF54165.1 - 0.21 11.0 0.1 0.47 9.9 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain GST_C_3 PF14497.1 CCF54166.1 - 3.4e-09 37.0 0.0 5.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF54166.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 CCF54167.1 - 1.1e-26 92.7 0.6 1.9e-26 91.9 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF54167.1 - 2.8e-10 39.8 0.0 4.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCF54167.1 - 0.0048 17.7 0.0 0.0089 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase OB_NTP_bind PF07717.11 CCF54168.1 - 9.6e-15 54.4 0.0 2.9e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCF54168.1 - 3.6e-12 46.1 0.5 1.1e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCF54168.1 - 1.4e-08 34.4 0.0 3.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF54168.1 - 3.2e-06 26.7 1.0 8.4e-05 22.1 0.7 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CCF54168.1 - 0.0018 17.2 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CCF54168.1 - 0.0022 18.1 0.2 0.018 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CCF54168.1 - 0.018 14.8 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CCF54168.1 - 0.028 13.8 0.1 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.11 CCF54168.1 - 0.032 13.4 0.1 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 CCF54168.1 - 0.059 13.3 0.5 0.51 10.2 0.1 2.7 3 1 0 3 3 3 0 AAA ATPase domain DUF605 PF04652.11 CCF54168.1 - 6.4 6.0 28.2 0.45 9.8 3.6 2.3 2 0 0 2 2 2 0 Vta1 like Pkinase PF00069.20 CCF54169.1 - 5.6e-71 238.7 0.0 6.9e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54169.1 - 1.5e-29 102.8 0.0 2.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF54169.1 - 0.021 14.5 0.1 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Phosphonate-bd PF12974.2 CCF54170.1 - 0.01 15.2 0.1 0.037 13.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 CCF54170.1 - 0.014 14.9 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 NMT1/THI5 like DUF4423 PF14394.1 CCF54170.1 - 0.13 11.8 0.2 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) F-actin_cap_A PF01267.12 CCF54171.1 - 8.9e-93 310.2 0.8 1.3e-92 309.6 0.6 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Caprin-1_C PF12287.3 CCF54171.1 - 0.063 12.6 0.4 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Hid1 PF12722.2 CCF54171.1 - 0.18 9.4 5.4 0.24 9.0 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GMC_oxred_N PF00732.14 CCF54172.1 - 3.5e-48 164.2 0.0 5.6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CCF54172.1 - 1.5e-35 122.6 0.0 2.4e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CCF54172.1 - 9.1e-06 24.7 0.1 0.0016 17.4 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF54172.1 - 0.00054 19.9 0.3 0.0024 17.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCF54172.1 - 0.00073 18.4 0.4 0.07 11.9 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 CCF54172.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF54172.1 - 0.0017 17.3 0.2 0.0027 16.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 CCF54172.1 - 0.094 11.8 0.1 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 CCF54172.1 - 0.097 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 CCF54172.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Calcipressin PF04847.7 CCF54173.1 - 1.5e-28 99.6 0.0 2.8e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Calcipressin Voldacs PF03517.8 CCF54173.1 - 1.5e-26 92.8 0.6 2.9e-24 85.4 0.0 3.2 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling RRM_1 PF00076.17 CCF54173.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L36e PF01158.13 CCF54174.1 - 2.9e-37 126.5 5.1 3.3e-37 126.3 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF1168 PF06658.7 CCF54174.1 - 0.13 11.8 3.6 0.17 11.4 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Fib_alpha PF08702.5 CCF54175.1 - 0.49 10.5 7.8 0.97 9.5 5.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GET2 PF08690.5 CCF54175.1 - 0.61 9.2 4.9 1.3 8.1 3.4 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 FlxA PF14282.1 CCF54175.1 - 1.5 8.8 16.0 6.9 6.6 4.7 4.0 2 1 1 3 3 3 0 FlxA-like protein AAA_13 PF13166.1 CCF54175.1 - 7.4 4.8 18.9 10 4.4 13.1 1.1 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.22 CCF54176.1 - 1e-15 57.9 1.6 1.3e-15 57.5 1.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCF54176.1 - 0.034 13.7 0.3 0.044 13.3 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MogR_DNAbind PF12181.3 CCF54176.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Glyco_transf_20 PF00982.16 CCF54177.1 - 4.5e-187 622.2 0.0 8.3e-139 463.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCF54177.1 - 0.012 15.0 0.1 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 GCV_T PF01571.16 CCF54178.1 - 2.2e-68 229.7 0.0 3.2e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCF54178.1 - 2.1e-25 88.5 0.2 4.3e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.3 CCF54178.1 - 0.13 11.9 0.1 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) FixG_C PF11614.3 CCF54179.1 - 0.04 14.0 0.9 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Abhydrolase_6 PF12697.2 CCF54180.1 - 4.5e-28 98.6 0.4 6.6e-28 98.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF54180.1 - 2e-26 92.9 0.1 4.7e-26 91.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCF54180.1 - 3.6e-12 46.2 0.0 1.4e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCF54180.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CCF54180.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 CCF54180.1 - 0.2 10.1 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family NUFIP1 PF10453.4 CCF54181.1 - 1.8e-14 52.9 2.7 1.8e-14 52.9 1.9 2.3 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 CCF54181.1 - 0.014 15.0 3.3 0.014 15.0 2.3 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCF54181.1 - 8.2 6.6 11.7 0.32 11.0 3.2 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SNF2_N PF00176.18 CCF54182.1 - 1.5e-56 191.3 0.0 3.4e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CCF54182.1 - 4.7e-06 26.3 11.0 4.7e-06 26.3 7.6 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCF54182.1 - 7.9e-06 25.4 8.8 7.9e-06 25.4 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF54182.1 - 1.5e-05 24.5 11.8 1.5e-05 24.5 8.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF54182.1 - 0.0003 20.7 12.1 0.0003 20.7 8.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCF54182.1 - 0.045 13.4 5.0 0.11 12.2 3.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Helicase_C PF00271.26 CCF54182.1 - 0.086 12.7 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCF54182.1 - 1.5 8.6 16.6 0.073 12.8 6.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Ribosomal_L4 PF00573.17 CCF54183.1 - 4.8e-71 238.1 0.0 7.3e-71 237.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 CCF54184.1 - 4.8e-42 143.0 0.2 5.5e-42 142.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SPA PF08616.5 CCF54186.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CCF54186.1 - 0.009 14.5 0.0 2 6.8 0.0 2.3 2 0 0 2 2 2 2 Transport protein Avl9 DENN PF02141.16 CCF54186.1 - 0.018 14.7 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain IZUMO PF15005.1 CCF54187.1 - 0.024 14.6 1.2 0.054 13.5 0.6 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion Ribosomal_L35p PF01632.14 CCF54188.1 - 0.65 9.9 3.1 0.74 9.7 0.7 2.2 2 1 0 2 2 2 0 Ribosomal protein L35 HCNGP PF07818.8 CCF54189.1 - 2.9e-15 56.0 1.1 4.8e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 HCNGP-like protein Toxin_62 PF15540.1 CCF54189.1 - 1.7e-05 24.9 0.1 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative toxin 62 PEX11 PF05648.9 CCF54190.1 - 9.9e-18 64.2 0.1 4.9e-17 61.9 0.1 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PHD PF00628.24 CCF54193.1 - 2.3e-10 39.9 8.2 4.7e-10 38.9 5.7 1.6 1 0 0 1 1 1 1 PHD-finger Cutinase PF01083.17 CCF54195.1 - 5.9e-37 127.1 2.4 6.6e-37 126.9 1.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 CCF54195.1 - 1.6e-05 24.4 0.1 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Bacteriocin_IIc PF10439.4 CCF54195.1 - 0.017 15.2 1.8 0.31 11.1 0.1 2.7 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Lipase_3 PF01764.20 CCF54195.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Glyco_hydro_3 PF00933.16 CCF54196.1 - 8.5e-84 281.0 0.0 1.3e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 CCF54196.1 - 9.2e-62 208.5 1.8 6.5e-61 205.7 0.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 CCF54196.1 - 6.6e-14 51.5 0.1 1.3e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PPP4R2 PF09184.6 CCF54197.1 - 2.5e-13 50.2 0.0 2.5e-13 50.2 0.0 2.5 1 1 1 2 2 2 1 PPP4R2 ABC_tran PF00005.22 CCF54199.1 - 6.7e-50 168.9 0.0 2.4e-28 99.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCF54199.1 - 2.1e-44 152.0 21.2 1.4e-27 96.8 2.6 3.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 CCF54199.1 - 8.4e-11 41.5 0.7 0.038 13.2 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCF54199.1 - 2.8e-10 40.6 0.1 0.17 11.7 0.1 4.3 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 CCF54199.1 - 1.5e-08 34.0 0.4 0.0011 18.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CCF54199.1 - 2.6e-07 30.2 0.2 0.036 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CCF54199.1 - 2.6e-05 24.6 10.0 4.3e-05 23.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCF54199.1 - 0.00012 22.1 0.5 0.33 10.8 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 CCF54199.1 - 0.00018 21.6 1.1 0.44 10.7 0.1 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CCF54199.1 - 0.00022 20.2 0.1 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 CCF54199.1 - 0.00027 21.0 0.4 0.7 10.0 0.1 3.7 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CCF54199.1 - 0.0006 18.9 0.1 0.14 11.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CCF54199.1 - 0.001 18.3 0.1 0.07 12.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCF54199.1 - 0.0018 17.7 0.3 1.1 8.6 0.2 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 CCF54199.1 - 0.0019 19.0 1.4 3.1 8.6 0.1 3.4 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 CCF54199.1 - 0.0053 17.2 0.5 2.4 8.6 0.0 3.2 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 CCF54199.1 - 0.011 15.6 0.6 2.2 8.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CCF54199.1 - 0.014 15.3 0.5 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CCF54199.1 - 0.018 14.5 0.2 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 CCF54199.1 - 0.019 14.6 0.6 4.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CCF54199.1 - 0.035 13.9 2.3 1.8 8.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CCF54199.1 - 0.044 14.0 0.7 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CCF54199.1 - 0.069 12.9 2.6 0.78 9.5 0.0 3.1 3 0 0 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 CCF54199.1 - 0.1 12.2 0.5 0.77 9.4 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase MRP-S32 PF10210.4 CCF54199.1 - 0.13 12.5 0.7 0.49 10.7 0.5 2.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 AAA_14 PF13173.1 CCF54199.1 - 0.13 12.1 0.2 13 5.6 0.1 2.9 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 CCF54199.1 - 0.2 10.7 1.7 14 4.7 0.0 2.6 3 0 0 3 3 3 0 KaiC UQ_con PF00179.21 CCF54200.1 - 2.4e-13 49.7 0.0 3.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF667 PF05018.8 CCF54200.1 - 0.036 13.2 0.0 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF667) CTK3 PF12243.3 CCF54201.1 - 9.5e-41 138.6 0.0 1.4e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 CCF54201.1 - 1.9e-12 47.0 10.0 3.8e-10 39.6 6.9 2.4 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus PI3Ka PF00613.15 CCF54202.1 - 4.7e-51 172.6 0.0 1e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCF54202.1 - 7.2e-44 150.0 0.0 7.5e-43 146.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCF54202.1 - 1e-39 135.5 0.0 1.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 CCF54202.1 - 0.0097 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Chromo PF00385.19 CCF54203.1 - 0.00061 19.4 0.1 0.0014 18.2 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PigN PF04987.9 CCF54204.1 - 9.4e-92 307.9 20.7 5.2e-90 302.2 12.4 2.2 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCF54204.1 - 3e-07 30.1 2.1 0.00022 20.7 0.2 3.0 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCF54204.1 - 0.0064 15.7 0.0 0.0096 15.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Mito_carr PF00153.22 CCF54205.1 - 5.5e-41 138.1 9.6 2.6e-17 62.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans_2 PF11951.3 CCF54207.1 - 1.7e-08 33.4 5.8 9.5e-06 24.4 0.2 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF54207.1 - 0.00013 21.7 9.4 0.00013 21.7 6.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Claudin_3 PF06653.6 CCF54207.1 - 0.25 11.0 0.0 0.44 10.2 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NAD_binding_7 PF13241.1 CCF54208.1 - 9.2e-28 96.5 0.0 1.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCF54208.1 - 1.5e-21 75.5 0.2 2.3e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCF54208.1 - 3.3e-09 35.5 0.2 6.9e-09 34.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Cnd3 PF12719.2 CCF54209.1 - 1.7e-85 286.6 1.5 1.3e-84 283.7 0.2 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CCF54209.1 - 1.4e-14 54.1 2.9 3.9e-08 33.4 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CCF54209.1 - 1.2e-12 46.7 4.8 0.015 15.3 0.0 5.9 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.1 CCF54209.1 - 1.3e-07 31.8 3.8 0.093 13.2 0.0 5.6 4 1 1 5 5 5 2 HEAT-like repeat Adaptin_N PF01602.15 CCF54209.1 - 1.9e-07 29.7 1.4 0.00019 19.9 0.2 2.3 2 0 0 2 2 2 2 Adaptin N terminal region MMS19_N PF14500.1 CCF54209.1 - 0.00069 18.9 1.0 0.013 14.8 0.1 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 CCF54209.1 - 0.0014 18.5 1.5 1.2 8.9 0.0 3.3 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 CCF54209.1 - 0.01 15.3 0.3 3.2 7.1 0.0 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) Vac14_Fab1_bd PF12755.2 CCF54209.1 - 0.07 13.5 0.0 34 4.9 0.0 3.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CCF54209.1 - 0.11 12.4 1.0 19 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Ribosomal_60s PF00428.14 CCF54209.1 - 2.2 8.7 22.6 0.15 12.4 3.8 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Myc_N PF01056.13 CCF54209.1 - 4.6 6.3 12.7 3.6 6.6 4.8 2.4 2 0 0 2 2 2 0 Myc amino-terminal region RNase_PH PF01138.16 CCF54210.1 - 1.5e-23 83.5 0.0 3.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCF54210.1 - 0.0014 18.5 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PDT PF00800.13 CCF54211.1 - 5e-64 215.2 0.0 1e-63 214.1 0.0 1.6 1 0 0 1 1 1 1 Prephenate dehydratase Pil1 PF13805.1 CCF54211.1 - 1.5e-22 80.0 0.1 3.4e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Eisosome component PIL1 Chitin_synth_1 PF01644.12 CCF54212.1 - 1.5e-87 291.5 0.1 2.2e-87 290.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCF54212.1 - 4.6e-33 112.7 0.2 9.9e-33 111.6 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCF54212.1 - 8.4e-25 87.1 6.2 9.4e-21 73.7 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCF54212.1 - 5.7e-08 32.7 0.9 5.7e-08 32.7 0.6 2.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCF54212.1 - 9.4e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3989 PF13150.1 CCF54212.1 - 0.21 11.0 1.7 0.53 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) zf-CCHC PF00098.18 CCF54213.1 - 0.0033 17.2 2.6 0.0033 17.2 1.8 5.5 5 2 0 5 5 5 1 Zinc knuckle Arrestin_N PF00339.24 CCF54214.1 - 8.8e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Zn_clus PF00172.13 CCF54216.1 - 1.6e-07 31.0 5.6 2.7e-07 30.3 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Formyl_trans_N PF00551.14 CCF54217.1 - 4.6e-28 97.9 0.0 6.9e-17 61.5 0.0 2.7 2 1 0 2 2 2 2 Formyl transferase Gelsolin PF00626.17 CCF54217.1 - 0.09 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Gelsolin repeat Histone PF00125.19 CCF54218.1 - 4.5e-22 77.9 0.1 5.6e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCF54218.1 - 0.026 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF814 PF05670.8 CCF54219.1 - 7.7e-22 76.9 0.0 1.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) OmpH PF03938.9 CCF54219.1 - 5.7 6.8 13.0 8.2 6.3 9.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 CCF54220.1 - 1e-62 211.6 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54220.1 - 8e-40 136.5 0.0 1.1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF54220.1 - 2.9e-08 33.0 0.0 4.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCF54220.1 - 0.073 12.3 0.1 0.16 11.2 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCF54220.1 - 0.094 12.4 0.1 0.43 10.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.8 CCF54220.1 - 1.9 8.3 10.3 2.6 7.8 7.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MutS_V PF00488.16 CCF54221.1 - 2.7e-43 148.0 0.0 1.2e-39 136.1 0.0 2.2 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 CCF54221.1 - 1.3e-20 74.0 2.4 2.1e-20 73.4 0.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CCF54221.1 - 0.0075 16.4 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV NB-ARC PF00931.17 CCF54221.1 - 0.011 14.5 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 CCF54221.1 - 0.017 14.6 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCF54221.1 - 0.057 12.8 0.4 0.82 9.0 0.3 2.6 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 CCF54221.1 - 0.13 11.2 0.0 0.32 9.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.15 CCF54221.1 - 0.2 10.3 0.0 0.46 9.1 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Zn_clus PF00172.13 CCF54222.1 - 1.1e-08 34.8 9.2 1.8e-08 34.1 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4127 PF13552.1 CCF54222.1 - 0.0096 14.3 0.2 0.016 13.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4127) DUF966 PF06136.8 CCF54222.1 - 0.1 12.0 7.0 0.18 11.1 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Chitin_synth_1 PF01644.12 CCF54223.1 - 1.1e-87 291.9 0.1 1.9e-87 291.1 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCF54223.1 - 4.9e-32 109.4 0.3 1.3e-31 108.0 0.2 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCF54223.1 - 4.6e-20 71.5 2.3 4.5e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 CCF54223.1 - 7.5e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCF54223.1 - 0.00013 21.7 12.6 0.0014 18.3 8.7 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 WD40 PF00400.27 CCF54224.1 - 0.017 14.9 0.0 9 6.3 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 CCF54225.1 - 1.1e-32 113.7 2.6 1.6e-32 113.2 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF54225.1 - 3.3e-12 46.3 0.0 5.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCF54225.1 - 5.3e-12 45.7 0.2 1.7e-09 37.5 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCF54225.1 - 7.5e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 CCF54225.1 - 0.00084 18.0 0.0 0.0012 17.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 CCF54225.1 - 0.039 13.2 0.0 0.55 9.4 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.11 CCF54226.1 - 6e-30 104.1 45.6 6e-30 104.1 31.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF54226.1 - 2.6e-09 36.1 33.0 4.8e-05 22.1 8.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 CCF54226.1 - 0.00029 19.3 37.2 0.0015 16.9 10.6 2.9 1 1 3 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 CCF54226.1 - 0.014 15.2 0.5 0.014 15.2 0.4 3.3 4 0 0 4 4 4 0 MFS_1 like family F-box-like PF12937.2 CCF54227.1 - 2.4e-05 23.9 0.6 2.4e-05 23.9 0.4 2.0 2 0 0 2 2 2 1 F-box-like Med16 PF11635.3 CCF54228.1 - 0.052 11.5 0.2 6.1 4.6 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 16 Peptidase_S24 PF00717.18 CCF54230.1 - 2.4e-08 33.5 0.2 7.5e-08 31.9 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Rad60-SLD PF11976.3 CCF54231.1 - 1.4e-09 37.4 0.1 3.2e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Synaphin PF05835.7 CCF54231.1 - 5.3 7.1 16.4 0.36 10.9 0.4 2.7 3 0 0 3 3 3 0 Synaphin protein bZIP_1 PF00170.16 CCF54232.1 - 2.5e-05 24.1 1.9 2.5e-05 24.1 1.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor IncA PF04156.9 CCF54232.1 - 0.0087 15.6 1.6 0.016 14.7 1.1 1.4 1 0 0 1 1 1 1 IncA protein HeH PF12949.2 CCF54232.1 - 0.012 15.1 0.1 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain AATF-Che1 PF13339.1 CCF54232.1 - 0.41 10.8 3.8 5.6 7.1 0.5 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor bZIP_2 PF07716.10 CCF54232.1 - 1.4 8.7 12.6 0.17 11.7 1.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper PX PF00787.19 CCF54233.1 - 4.5e-17 61.8 0.3 1.4e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 PX domain TelA PF05816.6 CCF54233.1 - 0.0026 16.4 0.8 0.0043 15.8 0.6 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) NYD-SP28 PF14772.1 CCF54233.1 - 0.0057 16.7 0.8 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 Sperm tail PSI_PsaE PF02427.12 CCF54233.1 - 0.13 11.6 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE Homeobox_KN PF05920.6 CCF54234.1 - 2.3e-18 65.5 0.4 1.8e-17 62.7 0.1 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CCF54234.1 - 1.5e-05 24.5 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain Nudix_N_2 PF14803.1 CCF54235.1 - 1.4 8.7 0.0 3.3 7.4 0.0 1.6 1 0 0 1 1 1 0 Nudix N-terminal PGM_PMM_I PF02878.11 CCF54236.1 - 1.3e-38 131.5 0.2 1.9e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCF54236.1 - 1.2e-26 92.9 0.0 2.2e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCF54236.1 - 2.4e-16 59.9 0.0 5.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCF54236.1 - 1.9e-10 40.5 0.0 4.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA_int_endo PF01974.12 CCF54237.1 - 1.6e-12 47.0 0.0 3.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Pkinase PF00069.20 CCF54238.1 - 1.6e-71 240.5 0.0 2e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54238.1 - 2.8e-31 108.5 0.0 3.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCF54238.1 - 4.1e-13 49.6 2.3 4.1e-13 49.6 1.6 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCF54238.1 - 0.0024 16.9 0.0 0.0044 16.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCF54238.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCF54238.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIB PF00382.14 CCF54239.1 - 4.3e-31 106.5 0.7 1.2e-16 60.2 0.0 3.4 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CCF54239.1 - 5.5e-28 97.0 5.2 5.5e-28 97.0 3.6 3.8 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CCF54239.1 - 6.4e-10 38.1 0.6 6.4e-10 38.1 0.4 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 CCF54239.1 - 4.2e-05 23.1 0.1 0.081 12.5 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-ribbon_3 PF13248.1 CCF54239.1 - 0.0039 16.3 1.0 0.008 15.3 0.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCF54239.1 - 0.022 14.2 1.0 0.045 13.2 0.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Subtilosin_A PF11420.3 CCF54239.1 - 0.028 14.4 0.1 0.066 13.2 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin subtilosin A Nucleo_P87 PF07267.6 CCF54239.1 - 0.12 11.0 4.4 0.038 12.6 0.1 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Mob1_phocein PF03637.12 CCF54241.1 - 8.5e-21 74.3 0.2 1.5e-20 73.5 0.1 1.4 2 0 0 2 2 2 1 Mob1/phocein family Fungal_trans PF04082.13 CCF54242.1 - 4.2e-08 32.3 0.5 9.1e-08 31.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF54242.1 - 1.6e-06 27.8 12.0 3.7e-06 26.7 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_2 PF07653.12 CCF54243.1 - 1.8e-08 33.7 0.0 5.5e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CCF54243.1 - 3.4e-06 26.5 0.0 1.3e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCF54243.1 - 0.0022 17.3 0.1 1.4 8.3 0.0 2.8 2 0 0 2 2 2 2 SH3 domain CsbD PF05532.7 CCF54244.1 - 1.2e-18 66.5 19.7 1.4e-10 40.7 4.1 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 CCF54244.1 - 0.0047 16.9 1.6 0.0066 16.5 0.4 1.9 1 1 1 2 2 2 1 Heat shock protein 9/12 DUF3659 PF12396.3 CCF54244.1 - 0.32 10.7 5.1 0.2 11.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) cobW PF02492.14 CCF54245.1 - 1.9e-48 164.2 4.6 1e-35 122.8 0.7 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain HIT PF01230.18 CCF54245.1 - 3e-23 82.1 0.1 1.2e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 HIT domain CobW_C PF07683.9 CCF54245.1 - 8.8e-19 67.0 0.5 3.6e-14 52.2 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain DcpS_C PF11969.3 CCF54245.1 - 0.0001 22.4 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MobB PF03205.9 CCF54245.1 - 0.00052 19.7 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CCF54245.1 - 0.003 16.3 0.1 0.048 12.4 0.0 2.5 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 CCF54245.1 - 0.012 15.0 0.1 3.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CCF54245.1 - 0.016 15.1 0.3 0.094 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCF54245.1 - 0.074 13.1 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCF54245.1 - 0.077 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CCF54245.1 - 0.089 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 CCF54245.1 - 0.12 11.5 0.4 3.6 6.6 0.0 2.4 1 1 1 2 2 2 0 KaiC CRAL_TRIO PF00650.15 CCF54246.1 - 2.2e-34 118.2 0.0 4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF54246.1 - 2.9e-11 43.3 0.3 1.1e-10 41.4 0.2 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCF54246.1 - 1.1e-08 35.1 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cupin_8 PF13621.1 CCF54247.1 - 4.8e-59 199.8 0.0 6.3e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCF54247.1 - 0.046 13.9 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase FHA PF00498.21 CCF54251.1 - 4.5e-08 33.0 0.0 1.5e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 FHA domain TFIID-18kDa PF02269.11 CCF54252.1 - 7.7e-14 51.2 0.0 6.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit RPAP1_C PF08620.5 CCF54253.1 - 4.3e-26 90.5 0.1 1.2e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCF54253.1 - 6.5e-06 25.6 0.2 1.5e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 CCF54253.1 - 0.00067 19.5 0.8 1.3 9.3 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat ETC_C1_NDUFA4 PF04800.7 CCF54254.1 - 9.8e-35 118.4 0.1 1.5e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Proteasome PF00227.21 CCF54255.1 - 7.8e-39 132.9 0.0 8.9e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.24 CCF54256.1 - 1.8e-39 134.9 0.0 3e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCF54256.1 - 2e-07 30.2 0.0 2.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCF54256.1 - 6.5e-07 29.5 0.2 3.8e-05 23.8 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCF54256.1 - 8e-06 25.9 0.1 0.00083 19.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CCF54256.1 - 9.8e-06 25.3 0.1 5.4e-05 22.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCF54256.1 - 1.5e-05 25.8 0.0 4.1e-05 24.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CCF54256.1 - 2.7e-05 24.0 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCF54256.1 - 5.7e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CCF54256.1 - 0.00014 21.3 1.0 0.01 15.2 0.2 2.5 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 CCF54256.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCF54256.1 - 0.00038 19.9 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCF54256.1 - 0.00049 19.3 0.2 0.0018 17.4 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCF54256.1 - 0.00069 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF54256.1 - 0.00085 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CCF54256.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CCF54256.1 - 0.0014 17.7 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 CCF54256.1 - 0.0021 18.1 0.0 0.0096 16.0 0.0 2.1 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 CCF54256.1 - 0.0028 16.4 0.0 0.0048 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 CCF54256.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.1 CCF54256.1 - 0.0042 16.6 2.2 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCF54256.1 - 0.0044 16.9 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF54256.1 - 0.0055 16.4 1.1 0.013 15.2 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_21 PF13304.1 CCF54256.1 - 0.0067 16.4 1.1 0.77 9.6 0.1 2.5 2 1 1 3 3 2 1 AAA domain Parvo_NS1 PF01057.12 CCF54256.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CCF54256.1 - 0.0086 15.7 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein CPT PF07931.7 CCF54256.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Guanylate_kin PF00625.16 CCF54256.1 - 0.012 15.0 0.0 0.037 13.4 0.0 1.8 3 0 0 3 3 1 0 Guanylate kinase NACHT PF05729.7 CCF54256.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 CCF54256.1 - 0.014 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 CCF54256.1 - 0.014 14.4 0.1 0.34 9.9 0.0 2.3 1 1 1 2 2 2 0 KaiC ABC_tran PF00005.22 CCF54256.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 CCF54256.1 - 0.027 14.0 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCF54256.1 - 0.047 13.3 0.0 0.68 9.5 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase KAP_NTPase PF07693.9 CCF54256.1 - 0.078 11.9 0.6 0.53 9.2 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain PhoH PF02562.11 CCF54256.1 - 0.084 12.1 0.2 0.19 10.9 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 CCF54256.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CCF54256.1 - 0.2 10.5 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_C PF00137.16 CCF54258.1 - 1.5e-29 101.7 30.3 6.8e-18 64.3 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Med6 PF04934.9 CCF54259.1 - 2.5e-46 156.7 0.0 3.1e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component AtpR PF12966.2 CCF54260.1 - 0.024 14.7 0.2 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 N-ATPase, AtpR subunit BRO1 PF03097.13 CCF54261.1 - 3.9e-113 378.0 0.5 3.9e-113 378.0 0.4 2.0 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCF54261.1 - 3.9e-58 196.7 11.7 7.7e-58 195.7 8.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Nucleoside_tran PF01733.13 CCF54262.1 - 3.1e-29 102.1 4.3 2e-28 99.4 3.0 2.2 1 1 0 1 1 1 1 Nucleoside transporter Tetraspannin PF00335.15 CCF54262.1 - 0.0028 16.9 4.2 0.014 14.6 0.1 2.6 1 1 1 2 2 2 2 Tetraspanin family START PF01852.14 CCF54263.1 - 0.00048 19.5 0.0 0.00068 19.0 0.0 1.5 1 1 0 1 1 1 1 START domain RRM_1 PF00076.17 CCF54264.1 - 2.8e-59 196.6 0.1 7.7e-17 60.7 0.0 6.7 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54264.1 - 1.4e-43 146.7 0.0 2.3e-09 37.1 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54264.1 - 5.1e-18 64.6 0.1 0.00017 21.3 0.0 6.3 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPPII PF12580.3 CCF54265.1 - 1.5e-53 181.0 0.4 3e-53 180.0 0.1 1.7 2 0 0 2 2 2 1 Tripeptidyl peptidase II Peptidase_S8 PF00082.17 CCF54265.1 - 6.1e-49 166.6 1.3 6.8e-49 166.5 0.2 1.6 2 0 0 2 2 2 1 Subtilase family Glycos_transf_3 PF00591.16 CCF54266.1 - 6.1e-77 258.4 0.0 6.5e-72 241.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain ETF PF01012.16 CCF54267.1 - 1.4e-37 128.9 0.2 1.9e-37 128.5 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Usp PF00582.21 CCF54267.1 - 0.051 13.7 1.9 0.061 13.5 0.5 1.7 2 0 0 2 2 2 0 Universal stress protein family EF-hand_1 PF00036.27 CCF54268.1 - 2.9e-26 88.7 8.1 2.2e-08 32.8 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CCF54268.1 - 1.9e-23 82.3 3.6 1.6e-14 53.7 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCF54268.1 - 1.7e-21 74.1 2.4 1.4e-05 24.5 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 CCF54268.1 - 2.8e-13 48.5 8.7 0.00017 20.7 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CCF54268.1 - 6e-13 48.1 8.6 0.001 18.6 0.2 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CCF54268.1 - 1.5e-09 37.5 2.6 0.011 15.4 0.0 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCF54268.1 - 0.00032 20.5 0.8 0.14 12.0 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCF54268.1 - 0.00039 20.4 1.1 0.21 11.6 0.0 3.3 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 CCF54268.1 - 0.043 12.4 0.3 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) S10_plectin PF03501.10 CCF54268.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain zf-C3HC4_3 PF13920.1 CCF54269.1 - 2.8e-09 36.4 7.0 2.7e-07 30.1 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCF54269.1 - 4.2e-08 32.8 7.9 1.7e-07 30.9 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCF54269.1 - 1.1e-07 31.7 7.8 1.2e-07 31.5 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF54269.1 - 6.5e-07 28.9 2.9 6.5e-07 28.9 2.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF54269.1 - 5.4e-06 26.0 8.6 7.8e-06 25.5 2.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCF54269.1 - 0.0013 18.3 1.5 0.0013 18.3 1.0 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCF54269.1 - 0.01 15.6 5.6 0.01 15.6 3.9 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING NOT2_3_5 PF04153.13 CCF54272.1 - 3.2e-38 130.6 3.1 3.2e-38 130.6 2.1 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ArfGap PF01412.13 CCF54273.1 - 9.1e-33 112.5 0.1 9.1e-33 112.5 0.0 2.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.5 CCF54273.1 - 0.28 10.6 1.6 0.77 9.2 1.1 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain UQ_con PF00179.21 CCF54274.1 - 5e-41 139.4 0.0 6.4e-41 139.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CCF54274.1 - 2.3e-24 84.7 0.6 4e-24 83.9 0.4 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CCF54274.1 - 0.001 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_E PF14462.1 CCF54274.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E ATP_bind_1 PF03029.12 CCF54275.1 - 4.9e-65 219.3 0.0 2.4e-56 190.9 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCF54275.1 - 0.00068 20.4 1.0 0.002 18.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCF54275.1 - 0.0065 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF54275.1 - 0.02 14.6 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 CCF54275.1 - 0.048 13.0 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 CCF54275.1 - 0.14 12.1 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DNA_pol_delta_4 PF04081.8 CCF54276.1 - 1.3e-20 73.8 0.3 1.6e-20 73.5 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 SIT PF15330.1 CCF54277.1 - 0.038 14.1 2.8 0.04 14.0 2.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4381 PF14316.1 CCF54277.1 - 0.12 12.4 2.7 0.12 12.4 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TadE PF07811.7 CCF54277.1 - 0.17 11.8 3.9 0.29 11.0 2.7 1.5 1 0 0 1 1 1 0 TadE-like protein Zn_clus PF00172.13 CCF54278.1 - 1.3e-06 28.1 9.5 2.7e-06 27.1 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 CCF54279.1 - 9.8e-30 103.5 25.9 1.8e-22 79.5 8.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF54279.1 - 8.5e-28 97.0 31.9 8.5e-28 97.0 22.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CCF54279.1 - 0.022 14.5 0.2 0.64 9.8 0.0 2.7 2 0 0 2 2 2 0 MFS_1 like family ATG22 PF11700.3 CCF54279.1 - 0.16 10.3 23.5 0.27 9.6 3.2 2.4 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like Fungal_trans PF04082.13 CCF54280.1 - 6.2e-26 90.8 0.0 1.3e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF54280.1 - 8.9e-10 38.3 6.2 8.9e-10 38.3 4.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 CCF54280.1 - 0.18 11.6 1.3 2.7 7.8 0.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper NYD-SP28_assoc PF14775.1 CCF54280.1 - 1.8 8.3 2.9 4.5 7.0 0.5 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain CUE PF02845.11 CCF54281.1 - 1.2e-12 47.0 0.0 2.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain Sec6 PF06046.8 CCF54281.1 - 0.00033 18.8 0.0 0.00067 17.8 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec6 Pex26 PF07163.7 CCF54281.1 - 0.32 9.8 2.4 0.65 8.8 1.7 1.4 1 0 0 1 1 1 0 Pex26 protein BAF1_ABF1 PF04684.8 CCF54281.1 - 2.4 6.9 10.1 4.6 5.9 7.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 CCF54283.1 - 1.6e-26 91.1 23.7 1.6e-08 34.0 0.5 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat COPI_assoc PF08507.5 CCF54284.1 - 0.14 11.8 2.7 0.18 11.4 0.1 2.2 3 0 0 3 3 3 0 COPI associated protein YtpI PF14007.1 CCF54284.1 - 2.7 7.9 5.9 1.3 8.9 1.0 2.6 2 1 0 2 2 2 0 YtpI-like protein Gly-zipper_Omp PF13488.1 CCF54285.1 - 0.017 14.7 2.7 0.017 14.7 1.8 3.7 4 0 0 4 4 4 0 Glycine zipper PepSY_TM PF03929.11 CCF54285.1 - 0.14 12.5 1.5 0.47 10.9 1.0 1.9 1 0 0 1 1 1 0 PepSY-associated TM helix adh_short PF00106.20 CCF54286.1 - 1.1e-12 48.1 0.0 1.5e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCF54286.1 - 1.9e-05 24.5 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 CCF54286.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Bap31 PF05529.7 CCF54287.1 - 8.6e-58 194.9 3.9 9.9e-58 194.7 2.7 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4446 PF14584.1 CCF54287.1 - 0.024 14.4 1.8 0.032 14.0 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 CCF54287.1 - 0.17 10.7 2.2 0.2 10.5 1.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) A_thal_3526 PF09713.5 CCF54288.1 - 0.042 13.9 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) GRP PF07172.6 CCF54288.1 - 0.091 13.2 20.3 0.32 11.4 11.1 2.4 2 0 0 2 2 2 0 Glycine rich protein family SE PF08491.5 CCF54289.1 - 5.9e-98 327.0 0.0 1.2e-97 326.1 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 CCF54289.1 - 4.7e-12 45.4 0.3 9e-08 31.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCF54289.1 - 5.4e-12 45.4 0.1 2e-11 43.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CCF54289.1 - 0.00022 21.1 0.4 0.00055 19.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCF54289.1 - 0.00023 21.1 0.0 0.00047 20.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF54289.1 - 0.00026 20.1 0.0 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 CCF54289.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 CCF54289.1 - 0.00092 18.1 0.0 0.042 12.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCF54289.1 - 0.001 18.0 0.6 0.013 14.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCF54289.1 - 0.0042 17.4 0.1 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 CCF54289.1 - 0.0053 16.5 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.7 CCF54289.1 - 0.013 14.4 0.1 0.23 10.3 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 CCF54289.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCF54289.1 - 0.093 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 CCF54289.1 - 0.12 11.3 0.2 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Oxidored_molyb PF00174.14 CCF54290.1 - 6.8e-40 136.2 0.0 1.1e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 CCF54290.1 - 3.4e-10 39.6 4.1 3.4e-06 26.7 2.3 2.4 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain Bromo_TP PF07524.8 CCF54291.1 - 8.4e-11 41.4 0.1 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 CCF54291.1 - 0.0018 18.3 2.4 0.0027 17.7 0.0 2.5 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CCF54291.1 - 0.026 14.7 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S Histone PF00125.19 CCF54291.1 - 0.064 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.17 CCF54292.1 - 1.1e-17 63.3 0.0 1.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54292.1 - 2.3e-13 49.9 0.0 4.3e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54292.1 - 1.8e-07 30.8 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 CCF54292.1 - 1.1 7.6 8.7 1.6 7.1 6.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Complex1_LYR_1 PF13232.1 CCF54293.1 - 1e-16 60.8 0.1 1.4e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCF54293.1 - 2.1e-09 37.0 6.2 1.8e-08 34.0 2.9 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) TIM PF00121.13 CCF54293.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Triosephosphate isomerase DUF4552 PF15089.1 CCF54293.1 - 0.16 10.7 0.6 0.2 10.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) tRNA_int_endo PF01974.12 CCF54294.1 - 8.7e-21 73.5 0.0 1.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CCF54294.1 - 5.7e-06 25.7 0.0 0.00023 20.6 0.0 2.4 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 CCF54295.1 - 8.8e-24 82.4 5.7 2e-06 27.4 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCF54295.1 - 0.00015 21.5 0.3 0.06 13.0 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CCF54295.1 - 0.0011 18.5 0.5 0.68 9.6 0.1 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CCF54295.1 - 0.0062 16.0 0.0 0.69 9.4 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain MT-A70 PF05063.9 CCF54297.1 - 1.2e-37 129.1 0.0 1.1e-26 93.4 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Iso_dh PF00180.15 CCF54298.1 - 3.3e-80 269.6 0.0 4e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OppC_N PF12911.2 CCF54298.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF572 PF04502.8 CCF54299.1 - 0.02 14.1 9.1 0.026 13.7 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4644 PF15486.1 CCF54299.1 - 0.023 14.6 0.9 0.032 14.1 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) MDFI PF15316.1 CCF54299.1 - 0.099 12.6 1.3 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor PRP1_N PF06424.7 CCF54299.1 - 0.57 10.5 7.5 3.7 7.8 0.3 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF4629 PF15442.1 CCF54299.1 - 1.3 9.1 9.4 0.34 11.0 3.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4629) DUF2435 PF10363.4 CCF54300.1 - 6.5e-27 93.2 0.0 2.3e-26 91.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CCF54300.1 - 0.00014 21.3 2.4 0.00024 20.5 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT PF02985.17 CCF54300.1 - 0.089 12.9 2.0 27 5.1 0.0 4.8 5 0 0 5 5 5 0 HEAT repeat NUDIX PF00293.23 CCF54301.1 - 4.9e-14 52.1 0.0 8.3e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Mod_r PF07200.8 CCF54302.1 - 3.6e-16 59.4 6.6 5e-15 55.7 0.3 2.4 3 0 0 3 3 3 2 Modifier of rudimentary (Mod(r)) protein Synaptobrevin PF00957.16 CCF54302.1 - 1 9.0 2.6 1.6 8.4 0.3 2.0 2 0 0 2 2 2 0 Synaptobrevin ESSS PF10183.4 CCF54303.1 - 0.00037 20.8 0.9 0.0011 19.3 0.0 2.2 3 0 0 3 3 3 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Acyl-CoA_dh_N PF02771.11 CCF54304.1 - 3.3e-25 88.8 0.0 6.4e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 CCF54304.1 - 3.9e-24 85.4 0.0 5.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CCF54304.1 - 4e-20 71.0 0.1 1.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CCF54304.1 - 2.5e-09 37.4 0.0 3.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Erv26 PF04148.8 CCF54305.1 - 1.3e-15 57.3 4.0 3.9e-14 52.5 2.8 2.0 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DEAD PF00270.24 CCF54306.1 - 8.3e-42 142.5 0.0 2.2e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54306.1 - 3.5e-25 87.6 0.1 1.6e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF54306.1 - 0.00094 19.0 0.3 0.0049 16.7 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Jun PF03957.8 CCF54306.1 - 0.33 10.6 2.2 1.4 8.5 1.0 2.1 2 0 0 2 2 2 0 Jun-like transcription factor ATP-synt_E PF05680.7 CCF54306.1 - 2.8 7.9 10.5 6.7 6.7 0.3 2.5 2 0 0 2 2 2 0 ATP synthase E chain SPRY PF00622.23 CCF54309.1 - 1.7e-06 28.1 0.0 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 SPRY domain HOOK PF05622.7 CCF54310.1 - 0.013 13.3 4.9 0.021 12.6 3.4 1.2 1 0 0 1 1 1 0 HOOK protein DUF4094 PF13334.1 CCF54310.1 - 0.14 12.5 1.3 0.49 10.8 0.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.4 CCF54310.1 - 7.6 6.3 16.4 4 7.2 1.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MRP-L27 PF09809.4 CCF54311.1 - 1.3e-06 27.9 2.7 1.9e-05 24.2 0.8 2.6 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L27 ABC_tran PF00005.22 CCF54312.1 - 6e-43 146.4 0.0 3.3e-21 76.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CCF54312.1 - 9.4e-21 73.4 2.9 9.4e-21 73.4 2.0 3.0 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 CCF54312.1 - 1.5e-17 64.5 4.1 0.0016 18.4 0.0 4.7 4 1 1 5 5 4 4 AAA domain AAA_29 PF13555.1 CCF54312.1 - 4.7e-09 35.6 0.4 0.0009 18.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CCF54312.1 - 8.7e-08 31.6 2.4 0.2 10.8 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCF54312.1 - 2e-06 28.2 18.9 0.0013 19.0 1.2 4.2 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 CCF54312.1 - 3.5e-06 26.9 0.1 0.0068 16.3 0.0 3.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CCF54312.1 - 3.5e-06 27.8 0.7 0.061 14.1 0.1 3.0 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCF54312.1 - 6.1e-06 26.7 0.0 0.095 13.1 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CCF54312.1 - 8.7e-06 25.0 0.0 0.0015 17.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCF54312.1 - 8.7e-06 25.9 1.3 0.14 12.2 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCF54312.1 - 9e-06 24.9 8.4 0.19 10.7 0.1 4.7 3 1 0 4 4 4 2 AAA ATPase domain NACHT PF05729.7 CCF54312.1 - 5.2e-05 22.9 0.1 0.34 10.5 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 CCF54312.1 - 5.7e-05 22.6 0.3 0.57 9.5 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 CCF54312.1 - 0.00028 20.9 0.1 0.41 10.6 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 CCF54312.1 - 0.0003 21.1 0.6 0.66 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 CCF54312.1 - 0.00048 19.6 0.3 0.44 9.9 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 CCF54312.1 - 0.0014 18.6 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCF54312.1 - 0.0015 18.3 4.1 0.11 12.2 0.0 3.8 2 1 1 3 3 3 1 Dynamin family AAA PF00004.24 CCF54312.1 - 0.002 18.3 0.0 6.6 6.9 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 CCF54312.1 - 0.0032 16.9 0.5 0.44 9.9 0.1 2.7 3 0 0 3 3 2 1 AAA-like domain MobB PF03205.9 CCF54312.1 - 0.0041 16.8 5.0 0.29 10.8 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CCF54312.1 - 0.0052 16.3 0.1 0.49 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCF54312.1 - 0.0052 15.7 0.3 2.6 6.8 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein FeoB_N PF02421.13 CCF54312.1 - 0.0073 15.5 0.1 0.069 12.4 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_19 PF13245.1 CCF54312.1 - 0.0082 15.8 0.5 1.7 8.4 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 CCF54312.1 - 0.0099 15.7 0.0 2.1 8.3 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DAP3 PF10236.4 CCF54312.1 - 0.013 14.4 1.1 3.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 CCF54312.1 - 0.014 15.3 0.2 18 5.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain cobW PF02492.14 CCF54312.1 - 0.015 14.7 0.2 2.7 7.3 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CCF54312.1 - 0.024 14.7 0.4 3.3 7.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.1 CCF54312.1 - 0.024 14.2 1.4 4.6 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 CCF54312.1 - 0.027 13.3 0.0 4.7 5.9 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 CCF54312.1 - 0.027 14.3 0.3 12 5.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Septin PF00735.13 CCF54312.1 - 0.029 13.3 0.1 4.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.7 CCF54312.1 - 0.05 12.8 1.9 7.1 5.8 0.4 3.2 2 1 0 2 2 2 0 Poxvirus A32 protein AAA_5 PF07728.9 CCF54312.1 - 0.08 12.6 2.8 0.81 9.4 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CCF54312.1 - 0.22 11.2 14.7 0.83 9.4 0.0 4.7 4 1 1 5 5 4 0 Domain of unknown function DUF87 SRP54 PF00448.17 CCF54312.1 - 0.23 10.8 3.5 3 7.2 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 CCF54312.1 - 5.9 6.5 8.0 3.5 7.3 0.1 3.6 5 0 0 5 5 3 0 NTPase Ribosomal_L23eN PF03939.8 CCF54312.1 - 8.2 6.5 8.8 27 4.8 6.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Mob1_phocein PF03637.12 CCF54313.1 - 1.3e-56 191.0 0.3 1.6e-56 190.7 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Asp_protease PF09668.5 CCF54314.1 - 4.2e-60 200.7 0.0 7.5e-60 199.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CCF54314.1 - 9.8e-12 44.1 0.0 2.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.1 CCF54314.1 - 2.3e-11 44.0 0.0 6.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCF54314.1 - 3.8e-07 29.8 0.1 1.9e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCF54314.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CCF54314.1 - 5.9e-06 26.1 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 CCF54314.1 - 0.00023 20.6 0.7 0.001 18.5 0.2 2.3 2 0 0 2 2 2 1 UBA-like domain Rad60-SLD PF11976.3 CCF54314.1 - 0.00034 20.2 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CCF54314.1 - 0.00045 19.9 0.2 0.0019 18.0 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain Herpes_capsid PF06112.6 CCF54314.1 - 1.4 8.9 17.9 0.053 13.5 2.9 3.5 3 1 1 4 4 4 0 Gammaherpesvirus capsid protein NIF PF03031.13 CCF54315.1 - 1.4e-42 145.0 0.0 2.4e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AdoMetDC_leader PF08132.6 CCF54315.1 - 0.25 11.2 3.2 20 5.2 0.0 2.5 2 0 0 2 2 2 0 S-adenosyl-l-methionine decarboxylase leader peptide Methyltransf_16 PF10294.4 CCF54316.1 - 5.5e-11 42.2 0.0 7.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCF54316.1 - 1.2e-05 25.8 0.0 3.4e-05 24.3 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCF54316.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CCF54316.1 - 0.015 14.3 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) P21-Arc PF04062.9 CCF54318.1 - 2.3e-75 252.1 0.0 2.6e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Nucleoplasmin PF03066.10 CCF54319.1 - 0.0045 16.5 3.4 0.0046 16.4 2.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin DUF3812 PF12757.2 CCF54319.1 - 0.076 12.9 5.2 0.11 12.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) Sigma70_ner PF04546.8 CCF54319.1 - 0.14 11.7 9.4 0.18 11.3 6.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 CCF54319.1 - 0.15 11.1 3.1 0.16 11.1 2.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.8 CCF54319.1 - 0.97 7.1 7.9 1.1 6.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.26 CCF54320.1 - 1.4e-07 31.4 0.3 0.00042 20.3 0.0 3.8 4 1 0 4 4 4 2 Myb-like DNA-binding domain DUF3783 PF12646.2 CCF54320.1 - 0.063 13.0 0.4 0.21 11.3 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) SR-25 PF10500.4 CCF54320.1 - 0.1 12.0 24.4 0.024 14.1 10.3 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.2 CCF54321.1 - 6.6e-12 44.9 3.2 6.6e-12 44.9 2.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CCF54321.1 - 4.2e-09 35.8 2.2 0.1 12.2 0.0 5.8 4 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCF54321.1 - 5.1e-08 32.5 4.5 0.98 9.2 0.0 5.6 4 2 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CCF54321.1 - 7.2e-06 25.3 7.9 11 6.5 0.1 7.7 8 3 0 8 8 8 2 Leucine Rich Repeat F-box PF00646.28 CCF54321.1 - 1.4e-05 24.5 0.8 1.4e-05 24.5 0.6 3.7 4 0 0 4 4 4 1 F-box domain Ste50p-SAM PF09235.5 CCF54321.1 - 0.097 12.7 0.8 55 3.8 0.0 3.7 3 0 0 3 3 3 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 CCF54321.1 - 3.9 8.0 12.9 52 4.7 0.0 6.9 8 0 0 8 8 8 0 Leucine rich repeat CBS PF00571.23 CCF54322.1 - 9.5e-20 70.1 4.7 8.2e-06 25.5 0.1 5.1 5 0 0 5 5 5 4 CBS domain DUF3237 PF11578.3 CCF54324.1 - 1e-29 102.8 0.0 1.1e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ELYS PF13934.1 CCF54325.1 - 4.3e-29 101.8 0.1 5.9e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Hist_deacetyl PF00850.14 CCF54326.1 - 2.6e-75 253.6 0.0 4e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_60s PF00428.14 CCF54326.1 - 0.024 15.0 1.5 0.24 11.7 1.9 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein RXT2_N PF08595.6 CCF54326.1 - 2.8 7.7 7.6 0.092 12.5 0.7 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Coatomer_E PF04733.9 CCF54327.1 - 3.5e-42 144.5 0.8 4e-42 144.3 0.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 CCF54327.1 - 3.3e-09 36.2 3.2 4.5e-07 29.4 1.7 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 CCF54327.1 - 8.1e-07 29.5 6.2 8.1e-07 29.5 4.3 3.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCF54327.1 - 0.00046 20.5 1.8 0.00046 20.5 1.2 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCF54327.1 - 0.00095 19.1 0.2 1.4 9.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCF54327.1 - 0.0013 18.4 2.4 0.011 15.6 0.0 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCF54327.1 - 0.0024 18.1 6.9 0.37 11.1 2.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCF54327.1 - 0.018 15.1 4.8 3.4 7.8 1.7 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF54327.1 - 0.019 14.5 0.2 0.24 11.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TMF_TATA_bd PF12325.3 CCF54327.1 - 0.023 14.3 0.7 0.49 10.1 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_12 PF13424.1 CCF54327.1 - 0.42 10.5 7.2 1.1 9.2 0.5 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.1 CCF54327.1 - 1.6 9.2 3.9 83 3.8 0.0 4.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_4 PF07721.9 CCF54327.1 - 6.1 7.5 0.0 6.1 7.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat PCI PF01399.22 CCF54330.1 - 1.8e-13 50.6 0.1 6.9e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain DUF4496 PF14908.1 CCF54330.1 - 0.057 13.3 0.0 0.28 11.0 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4496) HTH_Tnp_1 PF01527.15 CCF54330.1 - 0.75 9.7 4.3 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 Transposase Sybindin PF04099.7 CCF54331.1 - 6.4e-39 132.9 0.0 7e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCF54331.1 - 2.2e-07 30.8 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PTH2 PF01981.11 CCF54332.1 - 0.0082 15.8 1.4 0.2 11.3 1.0 2.1 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 TrmE_N PF10396.4 CCF54333.1 - 2.6e-26 91.8 0.0 7.2e-26 90.3 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CCF54333.1 - 4.8e-19 68.4 0.0 8.5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CCF54333.1 - 1.4e-18 67.0 0.0 6.2e-18 64.9 0.0 2.2 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CCF54333.1 - 5.1e-06 25.8 0.0 9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 CCF54333.1 - 0.00015 22.5 0.0 0.00033 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CCF54333.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.7 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 CCF54333.1 - 0.001 19.5 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 CCF54333.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCF54333.1 - 0.0076 16.2 0.0 0.021 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCF54333.1 - 0.011 15.2 0.0 0.067 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCF54333.1 - 0.056 13.5 0.0 0.29 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 CCF54333.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CCF54333.1 - 0.11 11.9 0.0 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CCF54333.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCF54333.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CCF54333.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase FUSC PF04632.7 CCF54334.1 - 9.1e-15 54.1 3.4 9.1e-15 54.1 2.4 3.5 5 0 0 5 5 5 1 Fusaric acid resistance protein family FUSC_2 PF13515.1 CCF54334.1 - 3.3e-13 49.6 5.6 3.3e-13 49.6 3.9 2.7 3 1 0 3 3 3 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 CCF54334.1 - 1.6e-08 33.7 7.9 5.5e-06 25.4 0.0 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF2422) ALMT PF11744.3 CCF54334.1 - 2.3e-07 29.8 1.0 6.9e-07 28.2 0.7 1.8 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF2421 PF10334.4 CCF54334.1 - 8.6e-07 28.7 2.3 2.4e-06 27.3 1.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 CCF54334.1 - 0.0001 22.1 2.4 0.00035 20.4 1.6 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) PepSY_TM_3 PF13706.1 CCF54334.1 - 0.43 10.0 4.7 0.14 11.5 0.2 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix SHS2_Rpb7-N PF03876.12 CCF54337.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF1426 PF07234.6 CCF54337.1 - 0.21 11.3 1.5 0.38 10.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Ras PF00071.17 CCF54338.1 - 3e-50 169.7 0.0 3.6e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF54338.1 - 4.2e-16 59.5 0.0 6.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF54338.1 - 2.5e-10 39.8 0.0 3.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF54338.1 - 3.6e-05 23.0 0.0 4.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCF54338.1 - 0.0015 17.3 1.3 0.79 8.3 0.0 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 CCF54338.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 CCF54338.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 CCF54338.1 - 0.043 13.9 0.1 0.13 12.3 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCF54338.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 CCF54338.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain KaiC PF06745.8 CCF54338.1 - 0.17 11.0 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 KaiC 14-3-3 PF00244.15 CCF54339.1 - 1.9e-118 393.7 5.6 2.2e-118 393.5 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 CCF54339.1 - 0.062 12.8 4.1 1.1 8.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) HisKA PF00512.20 CCF54339.1 - 0.17 11.8 1.6 2.5 8.1 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain LON PF02190.11 CCF54339.1 - 0.18 11.4 1.1 0.36 10.4 0.7 1.7 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain Adaptin_N PF01602.15 CCF54340.1 - 6.3e-122 407.5 12.0 7.9e-122 407.2 8.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CCF54340.1 - 8.9e-40 135.1 0.0 2.3e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 CCF54340.1 - 1.1e-17 64.3 0.0 3.6e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain zf-CCHC PF00098.18 CCF54341.1 - 2.6e-37 125.0 57.8 3.1e-07 30.0 2.7 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCF54341.1 - 2.7e-07 30.1 41.3 0.078 12.6 0.3 7.0 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 CCF54341.1 - 6.8e-05 22.5 37.9 0.028 14.1 0.2 7.0 4 2 3 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.1 CCF54341.1 - 0.00022 20.6 34.0 0.16 11.4 0.3 6.5 5 2 2 7 7 7 5 Zinc knuckle DUF3717 PF12512.3 CCF54342.1 - 0.031 13.9 0.1 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Thioredoxin PF00085.15 CCF54343.1 - 2.5e-23 81.7 0.1 3e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCF54343.1 - 6.6e-09 35.9 0.1 7.8e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCF54343.1 - 9.6e-08 32.0 0.2 3.8e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CCF54343.1 - 0.00019 21.0 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 CCF54343.1 - 0.00087 19.0 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 CCF54343.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CCF54343.1 - 0.013 15.2 0.1 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.6 CCF54343.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 CCF54343.1 - 0.026 14.0 0.7 2.4 7.7 0.2 2.2 1 1 1 2 2 2 0 Redoxin KaiB PF07689.7 CCF54343.1 - 0.12 11.8 0.2 0.41 10.1 0.0 1.9 1 1 1 2 2 2 0 KaiB domain RRN3 PF05327.6 CCF54344.1 - 3.4e-188 626.2 2.3 5.8e-188 625.5 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 GN3L_Grn1 PF08701.6 CCF54345.1 - 2.2e-24 85.1 20.3 2.2e-24 85.1 14.1 4.5 5 0 0 5 5 5 1 GNL3L/Grn1 putative GTPase TFIIF_alpha PF05793.7 CCF54345.1 - 0.00015 20.3 24.8 0.00015 20.3 17.2 3.6 3 1 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 CCF54345.1 - 0.0052 15.2 26.8 0.0092 14.4 5.9 2.3 2 0 0 2 2 2 2 SGT1 protein SCHIP-1 PF10148.4 CCF54345.1 - 0.0069 15.8 1.5 0.0069 15.8 1.0 3.4 3 0 0 3 3 3 1 Schwannomin-interacting protein 1 CENP-B_dimeris PF09026.5 CCF54345.1 - 0.014 15.6 1.8 0.014 15.6 1.2 5.2 5 0 0 5 5 5 0 Centromere protein B dimerisation domain MMR_HSR1 PF01926.18 CCF54345.1 - 0.014 15.3 0.0 0.064 13.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Daxx PF03344.10 CCF54345.1 - 2.4 6.5 48.8 0.59 8.5 12.8 3.2 3 0 0 3 3 3 0 Daxx Family DUF3661 PF12400.3 CCF54346.1 - 1.1e-39 135.4 0.8 1.1e-39 135.4 0.6 1.5 2 0 0 2 2 2 1 Vaculolar membrane protein LRR_4 PF12799.2 CCF54349.1 - 1e-16 60.1 20.0 4.4e-08 32.5 2.1 5.2 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.20 CCF54349.1 - 2.1e-15 56.1 0.1 3.4e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 CCF54349.1 - 7.7e-11 41.5 14.9 3.1e-07 30.0 0.9 5.4 5 1 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CCF54349.1 - 5.7e-07 28.6 10.3 1.7 8.9 0.0 6.8 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 CCF54349.1 - 2.3e-05 23.9 14.0 2.8 8.2 0.0 6.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 CCF54349.1 - 0.0001 21.9 12.6 1.2 9.5 0.1 6.7 6 0 0 6 6 6 1 Leucine rich repeat LRR_9 PF14580.1 CCF54349.1 - 0.046 13.2 0.6 5.6 6.4 0.0 3.1 2 1 2 4 4 4 0 Leucine-rich repeat DPBB_1 PF03330.13 CCF54350.1 - 0.0044 16.9 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RhoGEF PF00621.15 CCF54352.1 - 2.4e-24 86.2 0.0 3.4e-23 82.4 0.0 2.2 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 CCF54352.1 - 0.0017 18.5 0.1 0.0038 17.4 0.1 1.6 1 0 0 1 1 1 1 PH domain Peptidase_S26 PF10502.4 CCF54353.1 - 3.8e-07 29.7 0.0 6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CCF54353.1 - 1.5e-06 27.7 0.0 6.3e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like Prenyltransf PF01255.14 CCF54354.1 - 1e-75 253.7 0.0 1.3e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SHP PF03579.8 CCF54354.1 - 0.081 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Small hydrophobic protein WIF PF02019.13 CCF54355.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 WIF domain RNase_H PF00075.19 CCF54356.1 - 0.0093 16.3 0.0 0.029 14.7 0.0 1.8 2 0 0 2 2 2 1 RNase H Cytochrom_C_asm PF01578.15 CCF54357.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Cytochrome C assembly protein CNH PF00780.17 CCF54357.1 - 0.32 10.3 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 CNH domain Acetyltransf_1 PF00583.19 CCF54358.1 - 2.9e-16 59.2 0.1 3.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCF54358.1 - 6.4e-06 25.8 0.1 8.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCF54358.1 - 9.2e-06 25.7 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCF54358.1 - 0.00028 21.0 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCF54358.1 - 0.0003 20.6 0.0 0.00048 19.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF54358.1 - 0.006 16.5 0.0 0.0077 16.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCF54358.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CRAL_TRIO PF00650.15 CCF54359.1 - 1.9e-36 124.9 0.1 3.1e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCF54359.1 - 2.3e-13 50.0 0.2 2.3e-13 50.0 0.1 2.4 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain Methyltransf_16 PF10294.4 CCF54361.1 - 1.6e-16 60.2 0.2 7e-12 45.1 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CCF54361.1 - 0.00053 20.5 0.0 0.0016 19.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCF54361.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 CCF54361.1 - 0.015 15.6 0.0 0.088 13.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CCF54361.1 - 0.023 14.7 0.3 0.081 12.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain HMG_box PF00505.14 CCF54362.1 - 1.7e-21 76.2 17.3 2.5e-11 43.6 3.5 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCF54362.1 - 6.2e-19 68.1 12.6 5.2e-09 36.3 0.8 2.7 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.8 CCF54362.1 - 0.015 15.5 3.0 0.015 15.5 2.1 2.2 1 1 1 2 2 2 0 YABBY protein PP2C PF00481.16 CCF54363.1 - 2.3e-67 227.1 0.5 1.1e-51 175.7 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Pectate_lyase_3 PF12708.2 CCF54366.1 - 2.5e-74 250.1 5.0 8.1e-59 199.4 0.9 2.9 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 CCF54366.1 - 2.4e-05 23.7 1.8 0.23 10.9 0.0 2.9 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 CCF54366.1 - 0.61 9.8 8.5 0.073 12.8 1.5 2.7 3 1 0 3 3 3 0 Right handed beta helix region RVT_2 PF07727.9 CCF54367.1 - 2e-28 98.9 0.0 2.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2-Hacid_dh_C PF02826.14 CCF54368.1 - 5e-52 175.6 0.0 9.7e-52 174.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF54368.1 - 1.6e-15 56.7 0.0 2.4e-15 56.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCF54368.1 - 3.2e-05 23.8 0.2 7.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CCF54368.1 - 9.6e-05 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 CCF54368.1 - 0.0038 17.0 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 CCF54368.1 - 0.029 14.8 0.1 0.09 13.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Peptidase_M19 PF01244.16 CCF54368.1 - 0.042 12.7 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) RNase_T PF00929.19 CCF54369.1 - 1.6e-24 87.0 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Med15 PF09606.5 CCF54369.1 - 0.34 9.0 1.0 0.45 8.6 0.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SWIB PF02201.13 CCF54370.1 - 2.1e-27 94.5 0.0 3.2e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CCF54370.1 - 5.2e-06 26.1 0.2 3.3e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 DEK C terminal domain RR_TM4-6 PF06459.7 CCF54370.1 - 0.071 12.9 0.4 0.087 12.7 0.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 CCF54370.1 - 0.16 11.2 8.7 0.23 10.6 6.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vps5 PF09325.5 CCF54371.1 - 1.1e-12 47.7 4.0 1.6e-12 47.1 2.8 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCF54371.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.9 1 0 0 1 1 1 0 PX domain Myb_DNA-binding PF00249.26 CCF54372.1 - 4e-12 45.9 0.6 9e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCF54372.1 - 3.1e-08 33.6 0.9 6.7e-08 32.5 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain NuA4 PF09340.5 CCF54372.1 - 0.12 12.0 0.4 0.52 9.9 0.2 2.1 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 FimP PF09766.4 CCF54372.1 - 0.18 10.8 1.6 4.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Fms-interacting protein DUF342 PF03961.8 CCF54372.1 - 0.48 8.7 0.4 19 3.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Coatomer_WDAD PF04053.9 CCF54374.1 - 5.5e-157 523.1 0.0 2.1e-156 521.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CCF54374.1 - 8.7e-49 161.7 15.9 1.1e-10 40.9 0.4 8.8 11 0 0 11 11 11 6 WD domain, G-beta repeat EthD PF07110.6 CCF54375.1 - 0.0049 17.7 0.1 0.09 13.7 0.1 2.2 2 0 0 2 2 2 1 EthD domain Chorismate_synt PF01264.16 CCF54376.1 - 2.3e-129 430.8 0.1 3.5e-64 216.4 0.0 2.0 2 0 0 2 2 2 2 Chorismate synthase TBCC PF07986.7 CCF54377.1 - 1.1e-12 47.3 0.0 2.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Methyltransf_3 PF01596.12 CCF54378.1 - 8.7e-48 162.0 0.0 1.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 CCF54378.1 - 1e-10 42.3 0.0 2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54378.1 - 2e-06 28.3 0.0 5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 CCF54378.1 - 0.00094 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CCF54378.1 - 0.0049 16.8 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54378.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2013 PF09431.5 CCF54379.1 - 1.4e-46 157.7 6.5 1.5e-45 154.4 4.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2013) Palm_thioest PF02089.10 CCF54380.1 - 0.0011 18.0 0.0 0.0011 17.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase RecR PF02132.10 CCF54380.1 - 0.046 13.1 4.5 0.091 12.2 3.1 1.5 1 0 0 1 1 1 0 RecR protein BaffR-Tall_bind PF09256.5 CCF54380.1 - 0.36 10.4 2.3 0.5 9.9 0.9 1.9 2 1 0 2 2 2 0 BAFF-R, TALL-1 binding FA_hydroxylase PF04116.8 CCF54382.1 - 4.5e-16 59.2 13.5 4.5e-16 59.2 9.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3087 PF11286.3 CCF54382.1 - 0.0023 17.1 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3087) MBOAT PF03062.14 CCF54383.1 - 1.2e-47 162.6 1.8 1.2e-47 162.6 1.2 2.5 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_C14 PF00656.17 CCF54384.1 - 1e-62 212.0 0.1 1.3e-62 211.7 0.1 1.0 1 0 0 1 1 1 1 Caspase domain MRP-S33 PF08293.6 CCF54385.1 - 3.2e-22 78.2 0.1 4e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 HSP20 PF00011.16 CCF54386.1 - 0.0029 17.4 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pyr_redox_2 PF07992.9 CCF54387.1 - 8.9e-20 71.4 0.0 1.7e-14 54.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCF54387.1 - 1.5e-09 38.1 0.4 4.3e-09 36.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF54387.1 - 0.0072 16.4 0.0 8 6.4 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF54387.1 - 0.049 12.5 0.1 1.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein DUF4589 PF15252.1 CCF54389.1 - 0.041 13.6 0.3 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Iron_permease PF04120.7 CCF54391.1 - 0.05 13.1 0.1 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Low affinity iron permease RHD3 PF05879.7 CCF54392.1 - 2e-245 816.2 2.4 2.5e-245 815.9 1.7 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CCF54392.1 - 1.1e-07 31.2 0.8 2.5e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CCF54392.1 - 5.2e-06 26.3 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCF54392.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CCF54392.1 - 0.00012 22.5 0.2 0.00042 20.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CCF54392.1 - 0.0067 16.3 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 CCF54392.1 - 0.066 12.5 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras family NTF2 PF02136.15 CCF54393.1 - 2e-26 92.7 0.4 4.5e-26 91.5 0.2 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_6 PF14259.1 CCF54393.1 - 8.4e-07 28.8 0.1 1.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCF54393.1 - 9.1e-07 28.4 0.1 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54393.1 - 8.5e-05 22.3 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.1 CCF54393.1 - 0.01 14.8 0.5 0.016 14.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) 4HBT_3 PF13622.1 CCF54394.1 - 3e-31 109.0 0.0 3.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CCF54394.1 - 0.029 14.4 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily Ank_2 PF12796.2 CCF54395.1 - 5.9e-15 55.3 0.0 9.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCF54395.1 - 1.4e-12 47.7 0.2 3.7e-09 36.8 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCF54395.1 - 1.9e-11 43.1 0.1 2.1e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCF54395.1 - 8.8e-10 38.5 0.3 8.8e-08 32.1 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF54395.1 - 1.8e-08 33.7 0.1 0.00012 21.9 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_25 PF13649.1 CCF54395.1 - 0.08 13.3 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF3722 PF12519.3 CCF54396.1 - 7.6e-91 303.9 0.3 1.7e-90 302.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Nucleoporin_FG PF13634.1 CCF54397.1 - 1.3e-06 28.6 98.9 2e-06 28.0 26.3 3.3 1 1 2 3 3 3 2 Nucleoporin FG repeat region TBPIP PF07106.8 CCF54397.1 - 0.011 15.2 3.1 6.1 6.3 1.4 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2216 PF10226.4 CCF54397.1 - 0.027 13.9 0.4 0.052 13.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) Seryl_tRNA_N PF02403.17 CCF54397.1 - 5.5 7.0 8.0 11 6.1 0.2 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med19 PF10278.4 CCF54398.1 - 0.015 14.9 0.1 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF59 PF01883.14 CCF54399.1 - 1.3e-08 34.6 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Cyclin PF08613.6 CCF54400.1 - 2e-31 109.3 0.0 7e-31 107.6 0.0 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCF54400.1 - 4.1e-05 23.1 0.2 6.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Abhydrolase_6 PF12697.2 CCF54401.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCF54401.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein FAA_hydrolase PF01557.13 CCF54402.1 - 1.8e-46 158.3 0.0 2.3e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 CCF54402.1 - 2.4e-23 82.1 0.0 8.5e-23 80.3 0.0 2.0 2 1 1 3 3 3 1 Fumarylacetoacetase N-terminal p450 PF00067.17 CCF54403.1 - 1.7e-69 234.5 0.0 1.9e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 CCF54404.1 - 3e-25 88.5 0.2 5.3e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCF54404.1 - 4.7e-08 32.7 8.4 1.3e-07 31.3 5.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.18 CCF54405.1 - 5e-10 39.6 5.2 5e-10 39.6 3.6 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain PP2C_C PF07830.8 CCF54405.1 - 0.066 13.3 1.6 0.72 10.0 0.0 2.4 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Albumin_I PF08027.6 CCF54405.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Albumin I HgmA PF04209.8 CCF54406.1 - 1.9e-174 580.0 0.3 2.2e-174 579.8 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase 4HBT_2 PF13279.1 CCF54408.1 - 3.6e-09 37.0 0.0 6.3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily AMP-binding PF00501.23 CCF54409.1 - 4.9e-17 61.4 0.0 6.1e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 CCF54411.1 - 3.4e-12 45.8 0.0 4.8e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NRPS PF08415.5 CCF54411.1 - 1e-06 28.3 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Nonribosomal peptide synthase NicO PF03824.11 CCF54412.1 - 4.6e-35 121.3 8.4 1.2e-30 106.8 0.1 3.8 2 1 1 3 3 3 2 High-affinity nickel-transport protein DUF4231 PF14015.1 CCF54412.1 - 5e-05 23.2 0.1 0.16 11.9 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF4231) DUF1673 PF07895.6 CCF54412.1 - 0.5 9.8 2.0 4.7 6.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) Pkinase PF00069.20 CCF54413.1 - 7.6e-13 48.1 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Seadorna_VP7 PF07387.6 CCF54413.1 - 7.5e-06 24.9 0.0 1.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CCF54413.1 - 4e-05 23.4 2.7 0.00091 19.0 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCF54413.1 - 0.04 12.8 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CCF54413.1 - 0.08 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCF54413.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RRN3 PF05327.6 CCF54414.1 - 0.0096 14.0 0.7 0.012 13.7 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 tRNA_anti-codon PF01336.20 CCF54414.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RVT_2 PF07727.9 CCF54415.1 - 3.4e-64 216.1 0.5 3.9e-64 215.9 0.3 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCF54415.1 - 0.078 12.3 0.1 0.14 11.5 0.1 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SRF-TF PF00319.13 CCF54417.1 - 6.8e-20 70.0 0.0 1.1e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 CCF54417.1 - 0.00043 18.4 1.7 0.00043 18.4 1.2 1.8 2 0 0 2 2 2 1 CDC45-like protein Nop14 PF04147.7 CCF54417.1 - 0.013 13.4 1.5 0.023 12.6 1.0 1.4 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 CCF54417.1 - 0.085 12.3 4.3 0.16 11.5 3.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCF54417.1 - 0.53 9.4 6.7 1.2 8.3 4.7 1.5 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.8 CCF54417.1 - 0.93 9.0 8.6 0.17 11.4 2.6 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Sigma70_ner PF04546.8 CCF54417.1 - 2.3 7.8 8.3 4.4 6.8 5.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region LAT PF15234.1 CCF54417.1 - 4.3 6.7 9.4 0.68 9.3 2.5 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells Glypican PF01153.14 CCF54417.1 - 5.2 5.5 9.8 0.52 8.8 1.3 2.2 2 0 0 2 2 2 0 Glypican AT_hook PF02178.14 CCF54417.1 - 6.4 6.7 12.5 0.18 11.5 3.9 2.2 2 0 0 2 2 2 0 AT hook motif ABC1 PF03109.11 CCF54418.1 - 1e-24 86.8 0.1 1.9e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Paf67 PF10255.4 CCF54420.1 - 8e-161 535.4 0.1 1.1e-160 534.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 CCF54420.1 - 0.0018 18.0 0.7 0.013 15.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCF54420.1 - 0.0079 15.7 0.0 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Exo_endo_phos PF03372.18 CCF54421.1 - 6.4e-12 45.9 0.1 2.4e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family FMN_dh PF01070.13 CCF54422.1 - 3.4e-32 111.6 0.0 4.7e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase cNMP_binding PF00027.24 CCF54423.1 - 1.2e-37 127.5 0.0 3.5e-17 61.9 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.17 CCF54423.1 - 7.5e-16 58.6 9.9 1.9e-15 57.3 4.1 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase Glycos_transf_2 PF00535.21 CCF54424.1 - 3.8e-23 82.0 0.0 6.4e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCF54424.1 - 1.1e-08 35.1 0.0 8.7e-07 28.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCF54424.1 - 0.047 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CCF54424.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_C1_2 PF03051.10 CCF54425.1 - 7.1e-144 479.5 0.1 3.6e-142 473.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CCF54425.1 - 0.0035 17.2 5.0 0.51 10.1 0.0 3.1 3 1 0 3 3 3 2 Papain family cysteine protease PB1 PF00564.19 CCF54425.1 - 0.075 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 PB1 domain HrcA_DNA-bdg PF03444.10 CCF54425.1 - 0.088 12.2 0.2 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2-Hacid_dh_C PF02826.14 CCF54427.1 - 4.8e-52 175.6 0.0 7.8e-52 174.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF54427.1 - 3.4e-33 113.9 0.0 5e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCF54427.1 - 0.00023 21.0 0.1 0.00081 19.2 0.0 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CCF54427.1 - 0.0014 18.4 0.3 0.0041 16.9 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 CCF54427.1 - 0.12 11.9 0.8 3.8 7.1 0.2 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRP-alpha_N PF04086.8 CCF54431.1 - 3.5e-65 220.1 3.3 5.4e-65 219.5 2.3 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 CCF54431.1 - 1.8e-46 158.0 0.1 1.3e-45 155.2 0.0 2.2 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 CCF54431.1 - 4.4e-08 33.1 0.0 1.7e-07 31.2 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CCF54431.1 - 1.3e-06 27.9 0.0 3.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CCF54431.1 - 4.8e-05 22.2 0.8 9.9e-05 21.2 0.0 1.8 2 1 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 CCF54431.1 - 0.0037 17.4 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CCF54431.1 - 0.018 14.7 0.0 0.072 12.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCF54431.1 - 0.051 13.5 0.8 0.23 11.3 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Nucleoplasmin PF03066.10 CCF54431.1 - 0.76 9.2 8.9 1.3 8.4 6.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CCF54431.1 - 4.6 7.5 12.4 9.8 6.4 8.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PI3K_1B_p101 PF10486.4 CCF54431.1 - 5.3 4.4 7.2 0.92 6.9 1.1 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.7 CCF54431.1 - 8.1 5.6 9.3 15 4.7 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein ATP_bind_1 PF03029.12 CCF54432.1 - 7.3e-83 277.7 0.0 8.4e-83 277.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCF54432.1 - 3.9e-07 30.9 0.1 7.3e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 CCF54432.1 - 3.8e-06 26.4 0.0 9.3e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 CCF54432.1 - 0.00025 21.0 0.1 0.0051 16.8 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 CCF54432.1 - 0.00041 20.6 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCF54432.1 - 0.00043 19.2 0.0 0.00063 18.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCF54432.1 - 0.00069 19.1 0.0 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 CCF54432.1 - 0.00083 18.2 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 CCF54432.1 - 0.001 18.5 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCF54432.1 - 0.0011 19.1 0.0 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCF54432.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 CCF54432.1 - 0.0029 17.0 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 CCF54432.1 - 0.0035 17.5 0.0 0.05 13.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CCF54432.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCF54432.1 - 0.0051 16.2 0.7 0.059 12.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CCF54432.1 - 0.0055 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF54432.1 - 0.0056 16.5 0.0 0.027 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCF54432.1 - 0.0062 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 CCF54432.1 - 0.0078 15.8 0.0 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCF54432.1 - 0.0096 16.0 0.0 0.053 13.7 0.0 2.3 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 CCF54432.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 CCF54432.1 - 0.03 14.0 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 CCF54432.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCF54432.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.5 1 1 0 1 1 1 0 KaiC IstB_IS21 PF01695.12 CCF54432.1 - 0.044 13.2 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein CobU PF02283.11 CCF54432.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SRP54 PF00448.17 CCF54432.1 - 0.074 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 CCF54432.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CCF54432.1 - 0.1 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MipZ PF09140.6 CCF54432.1 - 0.15 11.0 0.0 1.4 7.9 0.0 2.2 1 1 0 1 1 1 0 ATPase MipZ Zeta_toxin PF06414.7 CCF54432.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin zf-RING_2 PF13639.1 CCF54433.1 - 1.2e-13 50.5 3.9 2e-13 49.9 2.7 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 CCF54433.1 - 8.9e-10 38.1 0.0 4.9e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 CCF54433.1 - 3.6e-07 30.1 4.5 5.9e-07 29.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF54433.1 - 2.7e-06 27.0 1.8 4.3e-06 26.3 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCF54433.1 - 6e-06 26.2 1.0 1.1e-05 25.4 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCF54433.1 - 1.6e-05 24.4 2.1 2.5e-05 23.8 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCF54433.1 - 0.00024 20.7 1.6 0.00037 20.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCF54433.1 - 0.033 14.0 1.1 0.071 12.9 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCF54433.1 - 0.086 12.8 3.2 0.48 10.4 2.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CCF54433.1 - 2.8 7.7 6.2 0.91 9.2 0.2 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Iso_dh PF00180.15 CCF54434.1 - 1.6e-117 392.3 0.0 1.9e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Cullin_binding PF03556.10 CCF54435.1 - 2.6e-34 117.8 1.3 4.2e-34 117.1 0.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CCF54435.1 - 2.7e-07 29.9 0.1 5.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain AHH PF14412.1 CCF54435.1 - 0.64 10.0 3.3 0.28 11.1 0.2 1.8 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4404 PF14357.1 CCF54435.1 - 0.79 10.1 3.8 7.4 7.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ribosomal_L5_C PF00673.16 CCF54436.1 - 2e-06 27.4 0.0 6.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCF54436.1 - 0.0039 16.9 1.1 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 CCF54437.1 - 4.9e-19 67.6 0.5 6.8e-19 67.1 0.4 1.2 1 0 0 1 1 1 1 LSM domain MRJP PF03022.11 CCF54437.1 - 0.033 13.3 0.0 0.041 13.0 0.0 1.0 1 0 0 1 1 1 0 Major royal jelly protein DUF1541 PF07563.6 CCF54437.1 - 0.081 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Aldedh PF00171.17 CCF54438.1 - 4.8e-106 354.8 0.0 5.8e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NOG1 PF06858.9 CCF54440.1 - 3.5e-28 97.2 0.1 6.3e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CCF54440.1 - 3.4e-27 93.9 2.6 8.6e-27 92.6 1.8 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CCF54440.1 - 8.6e-18 64.3 0.0 2.1e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF54440.1 - 3.9e-08 32.7 0.0 7.7e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCF54440.1 - 0.00034 21.1 0.0 0.00083 19.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CCF54440.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF258 PF03193.11 CCF54440.1 - 0.017 14.2 0.0 0.15 11.2 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCF54440.1 - 0.028 14.2 0.1 2.3 8.0 0.0 2.8 1 1 1 2 2 2 0 Dynamin family zf-C2H2 PF00096.21 CCF54443.1 - 6.1e-05 23.1 10.1 0.031 14.6 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCF54443.1 - 7e-05 22.9 13.6 0.00011 22.3 0.8 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCF54443.1 - 0.04 14.2 9.5 1.9 8.9 1.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CHORD PF04968.7 CCF54443.1 - 1.5 9.1 5.2 11 6.3 0.5 2.3 1 1 1 2 2 2 0 CHORD Aminotran_5 PF00266.14 CCF54444.1 - 1.1e-33 116.5 0.1 7.4e-26 90.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCF54444.1 - 3.3e-07 28.9 0.0 1.3e-06 27.0 0.0 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CCF54444.1 - 0.1 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase zf-met2 PF12907.2 CCF54445.1 - 1.5e-07 31.2 0.3 1.5e-07 31.2 0.2 2.0 3 0 0 3 3 3 1 Zinc-binding zf-Di19 PF05605.7 CCF54445.1 - 0.00077 19.5 0.6 0.0012 18.9 0.4 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF1644 PF07800.7 CCF54445.1 - 0.039 13.8 1.3 0.12 12.2 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-H2C2_5 PF13909.1 CCF54445.1 - 0.16 12.2 0.9 0.27 11.5 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain 4F5 PF04419.9 CCF54445.1 - 0.24 12.1 10.1 0.41 11.4 7.0 1.4 1 0 0 1 1 1 0 4F5 protein family MDM31_MDM32 PF08118.6 CCF54446.1 - 1.2e-120 403.3 11.9 2.5e-58 197.7 0.2 3.2 2 1 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins Ank_2 PF12796.2 CCF54448.1 - 1.7e-12 47.5 0.1 5.6e-12 45.8 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCF54448.1 - 2.3e-11 43.5 1.5 8.3e-07 29.0 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCF54448.1 - 4.6e-09 36.5 1.6 0.00015 22.1 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCF54448.1 - 1.3e-08 34.1 0.5 0.021 14.6 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CCF54448.1 - 2.3e-07 30.3 0.8 0.028 14.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Nrap PF03813.9 CCF54449.1 - 1.2e-249 830.7 0.0 1.5e-249 830.4 0.0 1.1 1 0 0 1 1 1 1 Nrap protein Nop14 PF04147.7 CCF54449.1 - 1.9 6.2 29.1 3.8 5.3 20.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CCF54449.1 - 3.1 5.7 16.8 5.6 4.8 11.7 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 CCF54449.1 - 4.8 6.1 22.9 8.6 5.3 15.8 1.4 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 CCF54449.1 - 8.9 6.0 23.8 20 4.9 16.5 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PI31_Prot_N PF11566.3 CCF54450.1 - 4.1e-32 110.9 0.0 5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 CCF54450.1 - 1.9e-13 50.8 16.9 1.9e-13 50.8 11.7 3.2 2 1 0 2 2 2 1 PI31 proteasome regulator DUF3747 PF12565.3 CCF54450.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Adaptin_N PF01602.15 CCF54451.1 - 1.3e-99 333.9 6.5 1.9e-99 333.3 4.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCF54451.1 - 3.6e-66 220.8 0.0 9.5e-66 219.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCF54451.1 - 9.5e-62 206.8 0.4 2.3e-61 205.5 0.1 1.8 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCF54451.1 - 2.6e-13 50.0 3.9 0.00039 20.6 0.0 4.6 3 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 CCF54451.1 - 5.9e-09 36.0 6.9 0.00087 19.1 0.0 4.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCF54451.1 - 2.3e-06 27.1 0.4 0.0048 16.8 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat DUF3810 PF12725.2 CCF54451.1 - 0.0043 15.9 0.0 0.0082 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) HEAT_EZ PF13513.1 CCF54451.1 - 0.0043 17.4 0.2 3.4 8.2 0.0 4.1 4 1 0 4 4 3 1 HEAT-like repeat ParcG PF10274.4 CCF54451.1 - 0.017 15.0 2.3 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Cullin PF00888.17 CCF54451.1 - 0.019 13.5 1.2 0.045 12.3 0.1 1.9 2 0 0 2 2 2 0 Cullin family Arm PF00514.18 CCF54451.1 - 1.7 8.5 4.2 84 3.2 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat zf-C2H2_3 PF13878.1 CCF54452.1 - 7.2e-13 47.8 2.1 1.3e-12 47.0 1.4 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.1 CCF54452.1 - 3.7e-12 45.8 0.0 1.7e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 CCF54452.1 - 0.033 14.1 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MutS_V PF00488.16 CCF54453.1 - 9.6e-79 264.0 0.1 1.4e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCF54453.1 - 2.6e-40 138.3 0.4 5.8e-40 137.2 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCF54453.1 - 4.1e-34 116.9 0.0 9.1e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCF54453.1 - 4.6e-10 39.6 0.0 1.4e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCF54453.1 - 1.2e-06 28.6 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Sec63 PF02889.11 CCF54454.1 - 1.1e-45 156.2 0.0 2.7e-45 154.9 0.0 1.5 1 1 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 CCF54454.1 - 1.8e-25 89.3 0.0 5.9e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54454.1 - 1.8e-10 40.4 0.0 4.3e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF54454.1 - 4.6e-08 33.1 0.0 8.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 CCF54454.1 - 0.0017 18.5 0.0 0.0064 16.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_19 PF13245.1 CCF54454.1 - 0.0082 15.8 0.5 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF4332 PF14229.1 CCF54454.1 - 0.013 15.4 0.1 0.45 10.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4332) AAA_22 PF13401.1 CCF54454.1 - 0.076 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CCF54455.1 - 7.7e-47 159.6 0.0 2.9e-46 157.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54455.1 - 5.2e-26 91.2 0.0 5e-25 88.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Herpes_ICP4_N PF03584.10 CCF54455.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Kdo PF06293.9 CCF54455.1 - 0.051 12.6 0.2 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCF54455.1 - 0.061 12.2 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Enolase_C PF00113.17 CCF54456.1 - 1.7e-144 480.3 0.1 2.3e-144 479.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCF54456.1 - 7.3e-58 194.1 0.2 1.1e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCF54456.1 - 0.002 18.1 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CCF54456.1 - 0.0051 17.3 0.0 0.011 16.3 0.0 1.6 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 CCF54456.1 - 0.046 12.6 0.3 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus EMP24_GP25L PF01105.19 CCF54457.1 - 7.8e-41 139.7 0.1 9.9e-41 139.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Laminin_II PF06009.7 CCF54457.1 - 0.053 13.2 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Laminin Domain II Nop10p PF04135.7 CCF54458.1 - 1.9e-20 72.3 0.1 2.2e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Josephin PF02099.12 CCF54459.1 - 4e-53 179.2 0.2 6.8e-53 178.5 0.2 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 CCF54459.1 - 0.85 9.3 35.1 0.038 13.5 0.9 4.6 5 0 0 5 5 5 0 Ubiquitin interaction motif Mito_carr PF00153.22 CCF54460.1 - 6.1e-57 189.3 6.3 5.5e-19 67.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BAP PF06639.6 CCF54461.1 - 0.11 12.2 1.3 0.15 11.7 0.2 1.7 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) FAM163 PF15069.1 CCF54461.1 - 0.41 11.1 3.0 0.43 11.1 0.2 2.2 2 0 0 2 2 2 0 FAM163 family Glyoxalase PF00903.20 CCF54462.1 - 0.00077 19.4 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCF54462.1 - 0.025 15.1 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase-like domain WD40 PF00400.27 CCF54464.1 - 1.6e-55 183.1 19.5 1.9e-09 37.0 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CCF54464.1 - 9e-06 24.2 0.0 1.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CCF54464.1 - 0.0021 16.8 3.1 1.3 7.7 1.5 3.3 2 1 0 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.1 CCF54464.1 - 0.01 16.0 1.5 47 4.4 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain Nbas_N PF15492.1 CCF54464.1 - 0.067 12.2 0.1 0.96 8.4 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal GTP_EFTU PF00009.22 CCF54465.1 - 1.1e-50 171.6 0.0 2.9e-50 170.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCF54465.1 - 9.7e-14 51.0 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCF54465.1 - 9.7e-10 38.1 0.1 6.4e-08 32.3 0.0 2.9 3 0 0 3 3 3 1 Elongation Factor G, domain II EFG_IV PF03764.13 CCF54465.1 - 3.5e-06 26.5 0.0 0.0002 20.8 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CCF54465.1 - 2.1e-05 24.4 0.0 6.8e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCF54465.1 - 0.012 15.7 0.0 0.057 13.5 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu domain 2 Dynamin_N PF00350.18 CCF54465.1 - 0.23 11.2 0.9 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Dynamin family MSP1_C PF07462.6 CCF54465.1 - 0.24 9.7 3.5 0.16 10.3 0.4 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Prp19_bind PF06991.6 CCF54466.1 - 0.67 9.1 6.1 0.085 12.1 0.6 1.8 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain ADH_zinc_N_2 PF13602.1 CCF54467.1 - 2.4e-09 38.1 0.0 1.1e-08 36.0 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF54467.1 - 2.7e-06 27.0 0.1 5.5e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCF54467.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RRM_1 PF00076.17 CCF54468.1 - 4.6e-17 61.4 0.0 7.2e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54468.1 - 3.4e-11 42.9 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54468.1 - 0.0033 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 CCF54469.1 - 3.1e-25 87.8 0.0 9.4e-25 86.2 0.0 1.8 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.8 CCF54469.1 - 0.00072 18.9 0.0 0.0037 16.6 0.0 2.2 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Abhydrolase_5 PF12695.2 CCF54470.1 - 1.6e-07 31.1 0.1 3.7e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCF54470.1 - 1.4e-05 25.0 0.7 2.7e-05 24.1 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CCF54470.1 - 0.00072 19.1 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 CCF54470.1 - 0.0033 16.7 0.1 0.026 13.8 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCF54470.1 - 0.0048 16.5 0.2 0.01 15.4 0.2 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CCF54470.1 - 0.014 15.6 0.1 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 CCF54470.1 - 0.045 13.1 0.1 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pex14_N PF04695.8 CCF54470.1 - 0.072 13.1 2.6 0.28 11.2 1.8 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF515 PF04415.7 CCF54470.1 - 0.96 7.6 4.9 1.4 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cofilin_ADF PF00241.15 CCF54472.1 - 5.4e-14 52.1 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ox_reductase_C PF08635.5 CCF54473.1 - 6.1e-77 255.8 0.1 8.8e-77 255.3 0.1 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 CCF54473.1 - 5.2e-26 91.5 0.0 1.3e-25 90.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M24 PF00557.19 CCF54474.1 - 3e-44 151.0 0.1 4.3e-44 150.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCF54474.1 - 1.3e-19 71.0 0.0 3.9e-18 66.2 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain RRM_1 PF00076.17 CCF54475.1 - 1.8e-26 91.5 0.1 5.5e-16 57.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54475.1 - 1.4e-12 47.3 0.0 5.7e-08 32.6 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54475.1 - 2e-11 43.5 0.0 4.5e-09 36.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCF54475.1 - 0.00015 21.4 0.0 0.00062 19.4 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCF54475.1 - 0.0012 18.6 0.9 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif CAF-1_p150 PF11600.3 CCF54475.1 - 1.9 7.7 15.5 3.6 6.9 10.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 CCF54475.1 - 2.5 7.9 6.8 5 6.9 4.7 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CCF54475.1 - 4.9 4.6 10.7 6.7 4.2 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 CCF54475.1 - 6.9 4.8 12.7 11 4.1 8.8 1.3 1 0 0 1 1 1 0 Transmembrane protein TBCA PF02970.11 CCF54476.1 - 2.1e-19 69.3 1.9 2.9e-19 68.9 1.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A UCH PF00443.24 CCF54477.1 - 1.9e-56 191.1 0.3 4.8e-56 189.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF54477.1 - 1.9e-21 76.7 1.2 8.2e-21 74.6 0.0 2.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Sgf11 PF08209.6 CCF54477.1 - 0.93 8.8 4.0 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Vac14_Fig4_bd PF11916.3 CCF54478.1 - 4.2e-80 267.1 9.0 1.9e-79 265.0 5.3 2.3 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CCF54478.1 - 4.7e-43 145.5 0.0 3.2e-40 136.4 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCF54478.1 - 6.1e-16 57.0 3.3 0.00018 21.2 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CCF54478.1 - 1.6e-09 37.8 4.0 0.2 11.9 0.0 5.2 4 1 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CCF54478.1 - 4.5e-05 23.8 2.4 2 9.0 0.0 5.8 7 0 0 7 7 7 2 HEAT-like repeat Cnd1 PF12717.2 CCF54478.1 - 0.0055 16.5 3.9 2.2 8.1 0.0 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 CCF54478.1 - 0.0059 15.3 3.2 0.022 13.5 0.1 3.0 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 CCF54478.1 - 0.006 15.9 0.9 4.1 6.6 0.0 4.0 3 1 0 4 4 4 1 CLASP N terminal APC_CDC26 PF10471.4 CCF54478.1 - 2.3 9.0 8.6 11 6.8 5.9 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Proteasome PF00227.21 CCF54479.1 - 1.2e-44 151.8 0.1 1.4e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 CCF54480.1 - 4.9e-27 91.1 12.1 1e-07 30.7 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCF54480.1 - 1.5e-24 85.9 3.1 1.3e-11 44.4 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CCF54480.1 - 6.3e-21 72.7 13.4 2.4e-07 29.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCF54480.1 - 2.6e-20 70.4 8.3 1.7e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CCF54480.1 - 3.7e-15 55.2 12.7 1.7e-05 24.3 0.8 4.6 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCF54480.1 - 2.7e-06 27.3 0.0 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CCF54480.1 - 2.1e-05 24.1 7.8 0.0053 16.4 0.2 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCF54480.1 - 2.8e-05 23.9 0.1 0.06 13.2 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain VCBS PF13517.1 CCF54480.1 - 0.037 14.3 1.7 8.1 6.8 0.1 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S13 PF00416.17 CCF54481.1 - 1.2e-24 86.7 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCF54481.1 - 7e-05 21.5 0.0 8.6e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PAG PF15347.1 CCF54481.1 - 0.0045 16.1 1.0 0.0055 15.8 0.7 1.1 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched PGC7_Stella PF15549.1 CCF54481.1 - 0.78 9.7 7.2 0.83 9.6 2.4 2.1 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain LisH PF08513.6 CCF54482.1 - 2.2e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 LisH Cpn60_TCP1 PF00118.19 CCF54483.1 - 1.7e-143 478.8 12.2 1.9e-143 478.6 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 CCF54483.1 - 0.028 13.6 0.2 0.071 12.3 0.1 1.8 2 0 0 2 2 2 0 Telomere recombination DNA_pol3_a_NII PF11490.3 CCF54483.1 - 0.089 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II LSM PF01423.17 CCF54484.1 - 1.5e-19 69.3 0.0 1.7e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCF54484.1 - 0.0016 18.3 0.0 0.0019 18.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.1 CCF54485.1 - 1.5e-13 49.9 6.3 1.5e-13 49.9 4.4 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 CCF54485.1 - 1.4e-09 37.1 13.1 1.4e-09 37.1 9.1 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.10 CCF54485.1 - 0.0015 17.3 5.0 0.0028 16.4 3.4 1.4 1 0 0 1 1 1 1 PUCC protein RasGAP PF00616.14 CCF54486.1 - 3.4e-33 114.9 0.0 6.7e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 CCF54486.1 - 4.6e-11 42.8 0.5 1.4e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 CCF54486.1 - 0.00032 20.5 0.0 0.00099 18.9 0.0 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal TCTP PF00838.12 CCF54487.1 - 2.9e-67 225.7 0.7 3.2e-67 225.6 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein GerPC PF10737.4 CCF54487.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC DUF3526 PF12040.3 CCF54487.1 - 0.096 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) AAA PF00004.24 CCF54488.1 - 5.3e-54 181.9 0.0 9.6e-38 129.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 CCF54488.1 - 7.3e-10 38.3 0.1 8.2e-09 34.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 CCF54488.1 - 9.7e-10 38.6 2.8 0.00025 21.1 0.1 4.5 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CCF54488.1 - 5.7e-09 35.8 0.1 0.00022 20.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCF54488.1 - 1.7e-08 34.5 0.1 9.1e-05 22.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCF54488.1 - 1.8e-08 34.5 0.0 0.0083 16.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 CCF54488.1 - 4.2e-08 33.1 0.0 0.00093 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCF54488.1 - 3e-07 31.2 0.0 0.026 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCF54488.1 - 3.3e-07 30.2 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCF54488.1 - 3.7e-07 29.9 0.2 0.028 14.0 0.0 3.6 3 1 0 3 3 3 2 NACHT domain RuvB_N PF05496.7 CCF54488.1 - 4.8e-07 29.0 0.1 0.014 14.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CCF54488.1 - 1.1e-06 27.6 0.0 0.011 14.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 CCF54488.1 - 1.1e-06 28.2 7.4 0.011 15.4 0.4 3.3 4 0 0 4 4 2 2 Part of AAA domain Mg_chelatase PF01078.16 CCF54488.1 - 1.4e-06 27.6 0.5 0.0087 15.2 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCF54488.1 - 1.9e-06 27.4 1.1 0.022 14.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_24 PF13479.1 CCF54488.1 - 2.5e-06 27.2 1.8 0.015 14.8 0.1 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCF54488.1 - 1e-05 25.6 0.0 0.035 14.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CCF54488.1 - 1.7e-05 25.1 0.0 0.058 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCF54488.1 - 2e-05 24.8 0.3 0.081 13.2 0.1 3.2 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 CCF54488.1 - 3.9e-05 23.6 0.0 0.07 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCF54488.1 - 7.8e-05 21.8 0.0 0.11 11.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin PhoH PF02562.11 CCF54488.1 - 8.8e-05 21.8 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 CCF54488.1 - 0.00011 22.0 0.3 0.39 10.3 0.1 3.7 2 2 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 CCF54488.1 - 0.00015 21.1 7.8 0.22 10.8 0.2 4.1 2 2 1 4 4 4 2 AAA domain NB-ARC PF00931.17 CCF54488.1 - 0.00019 20.4 0.1 0.35 9.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 CCF54488.1 - 0.0002 20.8 0.0 0.45 9.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CCF54488.1 - 0.00049 19.2 0.1 0.12 11.5 0.0 2.5 2 0 0 2 2 2 1 KaiC UPF0079 PF02367.12 CCF54488.1 - 0.00068 19.2 0.0 0.45 10.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CCF54488.1 - 0.00072 19.2 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 CCF54488.1 - 0.00078 18.3 0.0 0.68 8.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 CCF54488.1 - 0.00082 18.9 0.1 0.63 9.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCF54488.1 - 0.0016 18.0 0.0 0.64 9.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCF54488.1 - 0.0017 17.4 0.1 0.45 9.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 CCF54488.1 - 0.0017 18.4 0.3 1.9 8.5 0.1 3.5 2 1 0 2 2 2 1 Sigma-54 interaction domain cobW PF02492.14 CCF54488.1 - 0.0068 15.8 0.0 3 7.2 0.0 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.5 CCF54488.1 - 0.0071 15.5 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DAP3 PF10236.4 CCF54488.1 - 0.0081 15.1 0.0 2.3 7.0 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.24 CCF54488.1 - 0.014 14.9 0.5 20 4.6 0.1 3.6 3 1 0 4 4 4 0 DEAD/DEAH box helicase CDC48_N PF02359.13 CCF54488.1 - 0.025 14.4 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_10 PF12846.2 CCF54488.1 - 0.032 13.6 0.0 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 CCF54488.1 - 0.11 11.4 0.0 7.8 5.3 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain NUDIX PF00293.23 CCF54489.1 - 7.3e-13 48.3 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PP2C PF00481.16 CCF54490.1 - 7.1e-32 110.7 0.0 4.8e-29 101.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCF54490.1 - 0.027 13.8 0.0 0.08 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C He_PIG PF05345.7 CCF54494.1 - 1.2e-08 34.8 14.7 0.00033 20.6 0.4 5.0 4 1 0 4 4 4 3 Putative Ig domain Orbi_VP4 PF05059.7 CCF54494.1 - 0.016 13.0 0.1 0.023 12.4 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein TRAPP PF04051.11 CCF54495.1 - 7.7e-43 145.6 0.0 9.2e-43 145.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component AAA_32 PF13654.1 CCF54495.1 - 0.078 11.6 0.1 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Caps_synth_GfcC PF06251.6 CCF54496.1 - 0.048 12.8 4.3 0.12 11.4 3.0 1.6 1 0 0 1 1 1 0 Capsule biosynthesis GfcC PCI_Csn8 PF10075.4 CCF54497.1 - 2.4e-35 121.4 0.1 3.3e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CCF54497.1 - 8.8e-29 100.5 0.1 1.1e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CCF54497.1 - 0.042 14.1 0.4 1.1 9.5 0.1 2.8 2 1 0 2 2 2 0 PCI domain IMS PF00817.15 CCF54499.1 - 7.3e-37 126.4 0.0 1.5e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCF54499.1 - 1.9e-19 69.8 0.0 3.8e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 CCF54499.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 CCF54499.1 - 0.024 14.6 0.0 0.076 13.0 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif zf-trcl PF13451.1 CCF54499.1 - 0.07 12.7 0.1 5.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain Cyt-b5 PF00173.23 CCF54500.1 - 8.5e-25 86.3 0.0 1.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TB2_DP1_HVA22 PF03134.14 CCF54501.1 - 1.5e-07 31.0 0.4 2.7e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family AAA PF00004.24 CCF54502.1 - 6.1e-92 304.7 0.0 1.9e-46 157.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCF54502.1 - 2.6e-15 56.1 0.0 2.8e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCF54502.1 - 2e-11 44.1 0.8 0.0024 17.9 0.0 5.1 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 CCF54502.1 - 7.5e-11 41.9 0.7 0.0014 18.3 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCF54502.1 - 7.7e-11 42.2 0.0 0.00049 20.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCF54502.1 - 5e-10 39.6 8.0 0.0012 18.9 0.0 4.7 3 2 2 5 5 4 2 AAA ATPase domain AAA_17 PF13207.1 CCF54502.1 - 6.2e-10 39.9 0.0 6.3e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCF54502.1 - 5.4e-09 36.0 0.0 0.0027 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCF54502.1 - 6.2e-09 35.0 0.5 0.00022 20.0 0.0 2.8 2 1 1 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 CCF54502.1 - 1.2e-08 34.9 0.0 0.0033 17.3 0.0 2.6 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CCF54502.1 - 1.4e-07 30.8 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 CCF54502.1 - 3.9e-07 29.4 0.4 0.029 13.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCF54502.1 - 8.5e-07 28.5 0.7 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 CCF54502.1 - 1.1e-06 28.4 2.0 0.064 12.9 0.1 4.1 4 1 1 5 5 4 2 NACHT domain AAA_19 PF13245.1 CCF54502.1 - 1.5e-06 27.8 5.0 0.031 14.0 0.0 4.2 5 0 0 5 5 4 2 Part of AAA domain RNA_helicase PF00910.17 CCF54502.1 - 1.5e-06 28.3 0.0 0.06 13.5 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 CCF54502.1 - 4.6e-06 26.6 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCF54502.1 - 8.8e-06 26.0 0.0 0.031 14.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_3 PF07726.6 CCF54502.1 - 1.2e-05 24.8 0.0 0.026 14.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCF54502.1 - 1.6e-05 24.3 6.5 0.83 9.0 0.1 4.4 2 2 2 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 CCF54502.1 - 7.9e-05 22.7 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 CCF54502.1 - 0.00012 21.3 0.1 1.2 8.2 0.0 3.3 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 CCF54502.1 - 0.00013 22.3 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCF54502.1 - 0.00014 21.3 0.1 0.35 10.3 0.0 3.6 3 1 0 3 3 3 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CCF54502.1 - 0.00023 21.0 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 CCF54502.1 - 0.00045 19.8 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CCF54502.1 - 0.00047 19.1 0.1 0.33 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain SKI PF01202.17 CCF54502.1 - 0.001 18.9 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase PhoH PF02562.11 CCF54502.1 - 0.0013 18.0 0.6 1.2 8.3 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.8 CCF54502.1 - 0.0014 17.6 0.0 0.028 13.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 CCF54502.1 - 0.0055 15.4 0.0 2.1 6.9 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CCF54502.1 - 0.006 16.3 0.0 1.8 8.1 0.0 3.0 2 2 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 CCF54502.1 - 0.0077 16.0 0.0 5.2 6.8 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 CCF54502.1 - 0.01 15.4 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CCF54502.1 - 0.011 14.5 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.1 CCF54502.1 - 0.013 15.1 0.1 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCF54502.1 - 0.015 14.9 0.2 6.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CCF54502.1 - 0.016 14.0 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.10 CCF54502.1 - 0.021 14.5 0.1 2.8 7.6 0.0 2.7 2 1 1 3 3 2 0 NTPase PduV-EutP PF10662.4 CCF54502.1 - 0.15 11.5 0.0 9.1 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 CCF54502.1 - 0.23 11.0 0.0 2.9 7.4 0.0 2.5 3 0 0 3 3 2 0 Bacterial dnaA protein GLE1 PF07817.8 CCF54508.1 - 2.3e-75 252.8 0.0 5e-75 251.7 0.0 1.6 1 0 0 1 1 1 1 GLE1-like protein OGG_N PF07934.7 CCF54509.1 - 1.3e-26 92.8 0.1 2.5e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCF54509.1 - 4.1e-13 49.5 0.0 2.3e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCF54509.1 - 0.0014 18.2 0.0 0.0037 16.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2135 PF09906.4 CCF54509.1 - 0.01 15.7 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) NOB1_Zn_bind PF08772.6 CCF54510.1 - 2.6e-30 104.0 1.5 5.4e-30 103.0 1.0 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-TFIIIC PF12660.2 CCF54510.1 - 0.015 15.1 0.4 0.23 11.4 0.2 2.5 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Borrelia_P83 PF05262.6 CCF54510.1 - 0.17 10.0 15.8 0.28 9.4 11.0 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.10 CCF54510.1 - 8.6 4.8 7.1 13 4.2 4.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein YccV-like PF08755.6 CCF54511.1 - 8.6e-16 57.7 0.0 2.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 CCF54511.1 - 2e-14 53.3 0.0 1e-13 51.0 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 CCF54511.1 - 6.5e-09 35.3 0.1 1.9e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCF54511.1 - 6.2e-06 25.7 0.0 2.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 CCF54512.1 - 8.5e-19 66.6 11.0 0.00046 19.9 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 CCF54512.1 - 0.018 15.3 0.5 13 6.2 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain Apc4_WD40 PF12894.2 CCF54512.1 - 0.044 13.2 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-CCCH PF00642.19 CCF54513.1 - 2.8e-05 23.6 1.3 5.1e-05 22.8 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCF54513.1 - 0.65 10.0 6.0 1.4 9.0 4.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type TIP41 PF04176.8 CCF54514.1 - 8.7e-42 142.4 0.0 1.7e-39 134.9 0.0 2.8 1 1 1 2 2 2 2 TIP41-like family Nop14 PF04147.7 CCF54515.1 - 2.6e-262 872.5 12.4 3.3e-262 872.2 8.6 1.1 1 0 0 1 1 1 1 Nop14-like family GRIM-19 PF06212.7 CCF54516.1 - 1.1e-36 125.4 0.0 1.3e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Clathrin PF00637.15 CCF54517.1 - 1.2e-24 86.5 0.0 7.3e-24 83.9 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 CCF54517.1 - 0.0012 18.6 0.3 0.21 11.5 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Spore_coat_CotO PF14153.1 CCF54517.1 - 0.057 12.8 8.8 0.22 10.9 6.1 2.1 1 0 0 1 1 1 0 Spore coat protein CotO zf-RING_2 PF13639.1 CCF54517.1 - 0.12 12.1 2.3 1 9.2 0.3 2.4 2 0 0 2 2 2 0 Ring finger domain Vps39_2 PF10367.4 CCF54517.1 - 0.17 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPR_14 PF13428.1 CCF54517.1 - 1.4 9.7 6.4 8.1 7.3 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Cid2 PF09774.4 CCF54518.1 - 2.3e-34 118.6 0.2 3.9e-34 117.9 0.0 1.4 2 0 0 2 2 2 1 Caffeine-induced death protein 2 FAD-oxidase_C PF02913.14 CCF54519.1 - 1.7e-58 197.9 0.0 2.8e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCF54519.1 - 7.3e-36 122.6 0.6 1.6e-35 121.5 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Ilar_coat PF01787.11 CCF54519.1 - 0.054 13.0 0.0 0.25 10.9 0.0 1.9 1 1 1 2 2 2 0 Ilarvirus coat protein EpuA PF11772.3 CCF54519.1 - 0.074 12.5 0.3 0.21 11.0 0.2 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Metallophos PF00149.23 CCF54520.1 - 4.5e-42 143.7 0.6 5.7e-42 143.3 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ACC_central PF08326.7 CCF54520.1 - 0.12 10.5 0.1 0.2 9.7 0.1 1.3 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region Clathrin_lg_ch PF01086.12 CCF54521.1 - 3.3e-37 128.5 18.2 3.2e-34 118.8 8.4 2.3 1 1 1 2 2 2 2 Clathrin light chain Stathmin PF00836.14 CCF54521.1 - 0.022 14.3 5.7 0.032 13.8 4.0 1.2 1 0 0 1 1 1 0 Stathmin family PhoU PF01895.14 CCF54521.1 - 0.22 11.9 2.1 0.45 10.9 1.4 1.4 1 0 0 1 1 1 0 PhoU domain RR_TM4-6 PF06459.7 CCF54521.1 - 2.7 7.8 9.1 3.4 7.4 6.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Di19_C PF14571.1 CCF54521.1 - 3 8.2 5.4 1.4 9.2 1.7 1.9 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal Ribosomal_S17 PF00366.15 CCF54522.1 - 2.4e-30 104.3 2.6 3.5e-30 103.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L7Ae PF01248.21 CCF54523.1 - 4e-29 99.9 0.9 5e-29 99.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAP18 PF06487.7 CCF54524.1 - 1.2e-11 44.4 0.1 1.1e-10 41.2 0.1 2.1 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Rad60-SLD PF11976.3 CCF54524.1 - 0.19 11.4 0.6 21 4.8 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.20 CCF54525.1 - 9.7e-43 146.1 0.0 1.5e-23 83.3 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54525.1 - 7.3e-13 48.1 0.1 1.3e-09 37.5 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Spt20 PF12090.3 CCF54525.1 - 1.2e-05 24.7 2.7 2e-05 23.9 1.9 1.4 1 0 0 1 1 1 1 Spt20 family Pex14_N PF04695.8 CCF54525.1 - 0.69 9.9 9.2 2.2 8.3 6.4 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 CCF54525.1 - 1.1 8.2 3.6 2 7.3 2.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CCF54526.1 - 7.3e-188 625.3 0.0 8.5e-188 625.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) VID27 PF08553.5 CCF54527.1 - 0 1047.5 2.7 0 1047.2 1.9 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Isy1 PF06246.7 CCF54529.1 - 1.1e-78 264.1 9.7 1.1e-77 260.8 6.7 1.9 1 1 0 1 1 1 1 Isy1-like splicing family Ribosomal_L18e PF00828.14 CCF54530.1 - 2.9e-25 89.1 0.3 5.4e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Hyphal_reg_CWP PF11765.3 CCF54530.1 - 0.046 12.4 0.0 0.059 12.1 0.0 1.1 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal RRM_1 PF00076.17 CCF54532.1 - 1.6e-15 56.4 0.0 2.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54532.1 - 1.9e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54532.1 - 5.3e-10 38.9 0.0 7.1e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COesterase PF00135.23 CCF54533.1 - 2.3e-68 231.2 0.0 2.6e-67 227.7 0.0 1.9 1 1 0 2 2 2 1 Carboxylesterase family DnaJ PF00226.26 CCF54533.1 - 1.1e-14 53.8 0.5 2e-14 53.0 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CCF54533.1 - 9.9e-10 37.7 0.4 2.3e-09 36.5 0.3 1.6 1 0 0 1 1 1 1 CSL zinc finger Abhydrolase_3 PF07859.8 CCF54533.1 - 6.7e-05 22.5 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Iso_dh PF00180.15 CCF54534.1 - 1.4e-100 336.6 0.0 1.6e-100 336.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Polysacc_deac_1 PF01522.16 CCF54535.1 - 1.2e-18 66.9 0.0 2.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Collagen PF01391.13 CCF54535.1 - 0.017 14.6 5.1 0.033 13.7 3.5 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Macoilin PF09726.4 CCF54535.1 - 1.3 7.2 11.8 1.5 6.9 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0086 PF01868.11 CCF54536.1 - 9.5e-15 54.0 0.0 2.5e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function UPF0086 MCPVI PF02993.9 CCF54536.1 - 0.55 10.3 14.1 0.33 11.0 8.4 1.6 1 1 0 1 1 1 0 Minor capsid protein VI DUF4131 PF13567.1 CCF54537.1 - 0.0031 16.9 10.8 0.0034 16.8 7.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Pex24p PF06398.6 CCF54537.1 - 0.2 10.4 1.4 0.19 10.4 1.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Velvet PF11754.3 CCF54538.1 - 7.8e-67 224.8 0.0 1.1e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Velvet factor COX6A PF02046.10 CCF54539.1 - 1.4e-32 111.9 0.8 1.7e-32 111.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Arm PF00514.18 CCF54540.1 - 4.1e-67 219.9 30.0 8.2e-12 44.4 0.0 11.7 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCF54540.1 - 1.6e-21 76.3 16.1 0.00028 21.0 0.1 7.4 2 2 5 7 7 7 7 HEAT repeats HEAT PF02985.17 CCF54540.1 - 4.1e-15 54.4 22.6 0.57 10.4 0.0 11.1 12 0 0 12 12 11 5 HEAT repeat HEAT_EZ PF13513.1 CCF54540.1 - 2.4e-13 50.1 17.7 0.017 15.6 0.1 9.2 8 4 2 10 10 9 5 HEAT-like repeat Adaptin_N PF01602.15 CCF54540.1 - 5.3e-11 41.5 6.3 2e-07 29.7 0.0 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 CCF54540.1 - 2.3e-10 40.0 5.8 0.0023 17.0 0.1 3.4 1 1 1 4 4 4 3 Armadillo-like KAP PF05804.7 CCF54540.1 - 5.5e-10 37.8 0.1 1.2e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 CCF54540.1 - 6.9e-09 35.2 3.1 0.0019 17.3 0.4 4.4 2 1 1 3 3 3 3 V-ATPase subunit H HEAT_PBS PF03130.11 CCF54540.1 - 0.0061 16.9 7.4 89 4.0 0.0 7.4 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 CCF54540.1 - 0.011 15.6 2.9 12 5.8 0.0 4.4 2 1 3 5 5 5 0 V-ATPase subunit H CTNNBL PF08216.6 CCF54540.1 - 2.6 7.6 5.7 10 5.7 0.1 4.1 5 1 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Sigma70_r3 PF04539.11 CCF54541.1 - 3.4e-05 23.6 0.2 0.0046 16.8 0.0 3.0 2 0 0 2 2 2 2 Sigma-70 region 3 FeoC PF09012.5 CCF54541.1 - 0.096 12.4 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator zf-CCHC PF00098.18 CCF54542.1 - 0.0073 16.1 2.9 0.019 14.9 2.0 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CCF54542.1 - 0.43 10.2 5.3 0.73 9.5 2.7 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCF54542.1 - 3.6 7.3 4.9 6 6.6 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.21 CCF54543.1 - 7.4e-10 38.9 0.1 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Glyoxal_oxid_N PF07250.6 CCF54544.1 - 2.1e-36 125.2 0.0 1.8e-34 118.9 0.0 3.2 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 CCF54544.1 - 3e-21 75.3 0.2 5.5e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 CCF54544.1 - 0.001 18.7 7.2 0.13 12.0 0.1 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain Reg_prop PF07494.6 CCF54544.1 - 0.047 13.7 0.3 20 5.6 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller RCC1_2 PF13540.1 CCF54544.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.9 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat Maf PF02545.9 CCF54546.1 - 1.5e-43 148.1 0.0 1.9e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DAO PF01266.19 CCF54547.1 - 7.9e-16 57.9 1.2 7.1e-15 54.7 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase SMK-1 PF04802.10 CCF54548.1 - 1.3e-69 233.6 1.1 2.4e-69 232.7 0.8 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 WD40 PF00400.27 CCF54549.1 - 3.8e-66 216.7 24.8 9.7e-07 28.4 0.1 12.5 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 CCF54549.1 - 2.5e-21 75.6 1.5 4.1e-21 74.9 1.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCF54549.1 - 9.7e-11 40.4 2.9 0.087 10.9 0.1 6.5 3 2 3 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCF54549.1 - 0.0026 16.5 0.0 14 4.2 0.0 4.9 5 1 1 6 6 6 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCF54549.1 - 0.025 12.8 0.0 0.13 10.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Glyco_transf_15 PF01793.11 CCF54551.1 - 1.2e-131 438.6 6.8 1.5e-131 438.3 4.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DIOX_N PF14226.1 CCF54552.1 - 2.2e-14 53.9 0.0 5.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CCF54552.1 - 4.3e-13 49.3 0.0 8.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3419 PF11899.3 CCF54553.1 - 2.6e-141 470.7 0.2 3.4e-141 470.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 CCF54553.1 - 1e-08 34.9 0.0 2.3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF54553.1 - 3.8e-08 33.2 0.0 9.7e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF54553.1 - 2.9e-07 30.7 0.0 1.1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF54553.1 - 3.8e-07 29.4 0.0 2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CCF54553.1 - 9.3e-06 26.2 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54553.1 - 1.3e-05 25.6 0.0 0.00033 21.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF54553.1 - 4.9e-05 23.7 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCF54553.1 - 0.0029 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CCF54553.1 - 0.0059 16.6 0.0 0.044 13.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain RVT_1 PF00078.22 CCF54555.1 - 1.6e-29 102.7 0.0 3.7e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cellulase PF00150.13 CCF54557.1 - 5e-13 48.8 14.6 1.7e-12 47.1 10.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Albumin_I PF08027.6 CCF54557.1 - 0.00071 19.2 0.8 0.0014 18.3 0.6 1.4 1 0 0 1 1 1 1 Albumin I ATG_C PF09333.6 CCF54558.1 - 3.8e-21 75.0 0.1 1e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 CCF54558.1 - 1.5e-11 43.8 0.0 3.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Glypican PF01153.14 CCF54558.1 - 0.065 11.8 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Glypican RabGAP-TBC PF00566.13 CCF54560.1 - 1.1e-26 93.6 0.0 1.6e-22 80.0 0.0 2.6 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Cdc6_C PF09079.6 CCF54560.1 - 0.17 11.5 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 CDC6, C terminal FAD_binding_2 PF00890.19 CCF54561.1 - 5.9e-127 423.9 3.4 8.8e-127 423.3 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCF54561.1 - 1.2e-45 154.5 0.3 1.7e-45 153.9 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CCF54561.1 - 5.4e-06 26.4 0.0 0.023 14.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCF54561.1 - 7e-06 25.3 0.4 0.0028 16.8 0.1 2.5 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 CCF54561.1 - 8.9e-06 24.8 0.2 0.002 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 CCF54561.1 - 1.2e-05 24.3 1.1 0.03 13.1 1.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCF54561.1 - 0.0074 15.3 0.2 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CCF54561.1 - 0.09 12.8 0.5 3.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF54561.1 - 0.12 10.8 2.9 0.5 8.7 0.5 2.8 3 0 0 3 3 3 0 HI0933-like protein KTI12 PF08433.5 CCF54562.1 - 8.1e-55 185.9 0.0 1.3e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CCF54562.1 - 1e-06 28.6 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CCF54563.1 - 3.2e-47 160.1 0.0 4.6e-46 156.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54563.1 - 1.6e-23 82.3 1.5 4.6e-23 80.8 0.0 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCF54563.1 - 0.00019 20.3 0.0 0.00032 19.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PAP_assoc PF03828.14 CCF54564.1 - 5.6e-21 74.2 0.0 1.4e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CCF54564.1 - 9.5e-07 29.0 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA-synt_2d PF01409.15 CCF54566.1 - 2.5e-48 164.4 0.9 4.2e-26 91.6 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CCF54566.1 - 6.5e-24 83.9 0.2 1.6e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Ded_cyto PF06920.8 CCF54567.1 - 1.1e-46 158.4 0.1 2e-46 157.4 0.1 1.5 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 CCF54567.1 - 4.5e-34 117.6 0.0 1.4e-33 116.0 0.0 1.9 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Wax2_C PF12076.3 CCF54568.1 - 0.019 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain Sugar_tr PF00083.19 CCF54569.1 - 5.4e-98 328.5 18.7 1.3e-55 188.8 2.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCF54569.1 - 2.7e-28 98.7 22.0 2.7e-28 98.7 15.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCF54569.1 - 0.00068 17.9 2.6 0.0012 17.1 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 CCF54569.1 - 0.0013 18.7 4.0 0.17 12.0 2.4 2.9 2 0 0 2 2 2 1 Phage holin family 2 SNARE_assoc PF09335.6 CCF54570.1 - 4e-11 43.1 2.7 4e-11 43.1 1.9 2.9 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF1510 PF07423.6 CCF54570.1 - 0.031 13.6 0.5 0.052 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sld5 PF05916.6 CCF54571.1 - 2.8e-16 59.7 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein RhoGAP PF00620.22 CCF54572.1 - 1.4e-40 138.3 0.0 3.5e-40 137.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CCF54572.1 - 1.2e-14 54.4 0.0 6.8e-14 52.0 0.0 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCF54572.1 - 6.1e-12 45.5 0.9 2.8e-11 43.4 0.0 2.7 2 1 0 2 2 2 1 RasGEF N-terminal motif PH_9 PF15410.1 CCF54572.1 - 2.2e-06 27.8 0.0 5.8e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCF54572.1 - 1.4e-05 25.1 0.0 0.065 13.4 0.0 2.7 2 0 0 2 2 2 2 PH domain AMP-binding PF00501.23 CCF54573.1 - 1.1e-85 287.5 0.0 1.4e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF54573.1 - 3.7e-12 47.0 0.4 1e-11 45.6 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_11 PF13086.1 CCF54574.1 - 2.8e-69 233.2 1.9 4.9e-69 232.5 1.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CCF54574.1 - 7.1e-61 205.0 0.0 1.3e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF54574.1 - 1.7e-11 43.7 2.5 2e-11 43.4 0.3 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCF54574.1 - 2.7e-07 30.3 2.3 0.00017 21.2 0.2 3.0 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCF54574.1 - 2.1e-06 27.4 0.5 0.055 12.9 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCF54574.1 - 0.00036 19.9 1.7 0.073 12.3 1.2 2.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 CCF54574.1 - 0.00062 19.2 0.2 0.002 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 CCF54574.1 - 0.0011 18.4 0.5 0.57 9.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_23 PF13476.1 CCF54574.1 - 0.011 16.0 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Annexin PF00191.15 CCF54574.1 - 0.013 15.4 0.1 0.092 12.6 0.0 2.2 2 0 0 2 2 2 0 Annexin Helicase_RecD PF05127.9 CCF54574.1 - 0.013 15.1 3.5 0.17 11.5 0.0 3.0 1 1 1 2 2 2 0 Helicase CCDC92 PF14916.1 CCF54574.1 - 0.019 14.5 2.0 0.032 13.8 0.4 2.2 3 0 0 3 3 2 0 Coiled-coil domain of unknown function AAA_22 PF13401.1 CCF54574.1 - 0.022 14.9 1.5 1.5 8.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.1 CCF54574.1 - 0.025 14.7 0.0 0.076 13.1 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain GreA_GreB_N PF03449.10 CCF54574.1 - 0.045 13.8 0.3 0.045 13.8 0.2 2.0 2 0 0 2 2 1 0 Transcription elongation factor, N-terminal AAA PF00004.24 CCF54574.1 - 0.087 13.0 0.6 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cep57_MT_bd PF06657.8 CCF54574.1 - 0.094 12.6 2.1 0.26 11.2 1.5 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 CCF54574.1 - 2.9 7.9 9.0 1.1 9.3 3.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SnoaL PF07366.7 CCF54575.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase CDC50 PF03381.10 CCF54576.1 - 2e-95 319.1 0.2 2.5e-95 318.8 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Sec7 PF01369.15 CCF54577.1 - 2.8e-60 203.2 0.0 5.8e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCF54577.1 - 4.3e-15 55.5 2.9 1.2e-09 37.8 0.2 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal AAR2 PF05282.6 CCF54578.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Pkinase PF00069.20 CCF54581.1 - 3e-57 193.7 0.0 3.5e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54581.1 - 1.1e-19 70.4 0.0 1.6e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF54581.1 - 4.4e-07 29.8 0.0 4.9e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCF54581.1 - 0.022 14.3 0.2 0.022 14.3 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 CCF54581.1 - 0.026 13.5 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2456 PF10445.4 CCF54582.1 - 7.6e-29 99.4 1.8 1.5e-28 98.5 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) RRM_1 PF00076.17 CCF54583.1 - 1e-43 146.8 0.0 5.9e-19 67.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54583.1 - 1.3e-34 117.9 0.0 1.2e-12 47.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54583.1 - 7.7e-20 70.4 0.0 8e-09 35.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCF54583.1 - 0.066 12.9 0.0 2.4 7.9 0.0 2.6 2 1 0 2 2 2 0 Limkain b1 SNF2_N PF00176.18 CCF54584.1 - 1.5e-82 276.7 1.8 3.1e-82 275.7 1.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF54584.1 - 1.2e-17 63.5 0.0 8.8e-17 60.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 CCF54584.1 - 3.9e-17 61.7 7.1 3.9e-17 61.7 4.9 3.8 4 0 0 4 4 4 1 HSA Bromodomain PF00439.20 CCF54584.1 - 4.2e-15 55.4 0.0 1.1e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CCF54584.1 - 3e-14 52.9 0.5 3e-14 52.9 0.4 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CCF54584.1 - 1.2e-12 46.9 0.7 1.2e-12 46.9 0.5 2.0 2 0 0 2 2 2 1 QLQ DUF3138 PF11336.3 CCF54584.1 - 0.4 8.8 4.2 0.87 7.6 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RNA_pol_L_2 PF13656.1 CCF54585.1 - 2.3e-28 97.4 0.0 3e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCF54585.1 - 1.3e-11 43.4 0.0 1.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIS_M PF07500.9 CCF54586.1 - 6.6e-17 61.6 0.2 9.5e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DUF218 PF02698.12 CCF54587.1 - 6.9e-05 22.3 0.0 0.37 10.2 0.0 2.2 2 0 0 2 2 2 2 DUF218 domain Usp PF00582.21 CCF54588.1 - 5e-20 72.1 0.1 7.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Toprim_4 PF13662.1 CCF54588.1 - 0.00061 19.7 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Toprim domain PHD PF00628.24 CCF54589.1 - 4.4e-09 35.8 7.2 6.9e-09 35.2 5.0 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 CCF54589.1 - 1e-08 35.4 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding CDC27 PF09507.5 CCF54589.1 - 0.077 12.2 17.6 0.11 11.6 12.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PHD_2 PF13831.1 CCF54589.1 - 0.63 9.3 2.8 1.1 8.6 2.0 1.3 1 0 0 1 1 1 0 PHD-finger EF1_GNE PF00736.14 CCF54590.1 - 3.8e-28 96.9 0.8 3.8e-28 96.9 0.5 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CCF54590.1 - 8.4e-14 51.4 4.0 8.4e-14 51.4 2.8 2.7 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CCF54590.1 - 5.3e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCF54590.1 - 0.00027 20.7 0.5 0.0027 17.5 0.3 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCF54590.1 - 0.019 14.9 0.2 0.053 13.5 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_ligase_A_M PF01068.16 CCF54591.1 - 9.5e-09 34.9 0.0 2.9e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CCF54591.1 - 4.3e-05 23.1 0.0 0.00013 21.5 0.0 1.7 2 0 0 2 2 2 1 DNA ligase OB-like domain DUF1153 PF06627.6 CCF54591.1 - 0.014 15.2 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) FMN_dh PF01070.13 CCF54591.1 - 0.068 12.0 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ORC5_C PF14630.1 CCF54592.1 - 4.1e-52 177.3 0.2 1.2e-49 169.1 0.2 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus DUF3292 PF11696.3 CCF54593.1 - 9.4e-190 631.6 2.3 6.1e-187 622.4 1.6 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.6 CCF54593.1 - 0.21 10.3 0.0 0.54 8.9 0.0 1.7 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Trypsin_2 PF13365.1 CCF54595.1 - 6e-06 26.2 1.0 4.4e-05 23.4 0.7 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain MRP-L20 PF12824.2 CCF54596.1 - 1.4e-33 116.1 6.3 2.6e-33 115.3 4.4 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pyr_redox_2 PF07992.9 CCF54596.1 - 2.7e-05 24.1 0.0 0.00019 21.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF54596.1 - 0.00057 19.9 0.1 0.0017 18.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCF54596.1 - 0.0013 18.5 0.0 0.062 13.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 CCF54596.1 - 0.0099 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 CCF54596.1 - 0.05 13.1 0.2 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DUF3818 PF12825.2 CCF54597.1 - 3.3e-122 407.4 0.2 4.4e-122 407.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCF54597.1 - 9.1e-42 141.9 1.1 2.3e-41 140.6 0.8 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 CCF54597.1 - 1.5e-09 37.6 0.0 8.8e-09 35.1 0.0 2.4 1 1 0 1 1 1 1 PX domain Nop14 PF04147.7 CCF54597.1 - 0.2 9.5 9.4 0.35 8.7 6.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CCF54597.1 - 1.7 6.6 6.4 2.9 5.8 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CCF54597.1 - 5.4 6.3 11.2 0.1 11.9 2.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Aminotran_1_2 PF00155.16 CCF54598.1 - 6.2e-33 114.2 0.0 8.9e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DeoC PF01791.4 CCF54599.1 - 9.9e-46 155.9 3.4 1.1e-45 155.7 2.4 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 CCF54599.1 - 0.024 13.9 1.4 0.076 12.2 0.1 2.2 2 1 1 3 3 3 0 Histidine biosynthesis protein TPR_12 PF13424.1 CCF54600.1 - 6.8e-07 29.1 2.2 0.24 11.3 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCF54600.1 - 0.00064 19.3 0.9 4.4 7.0 0.1 3.6 3 1 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 CCF54600.1 - 0.0023 17.5 0.2 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCF54600.1 - 0.0028 17.4 3.3 4.4 7.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCF54600.1 - 0.015 15.8 2.3 6.1 7.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCF54600.1 - 0.041 13.4 0.2 15 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 CCF54600.1 - 0.061 13.1 0.3 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TPR_7 PF13176.1 CCF54600.1 - 0.08 12.7 0.3 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCF54600.1 - 0.92 10.2 4.7 17 6.2 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MOZ_SAS PF01853.13 CCF54601.1 - 9.9e-60 201.0 0.1 4.5e-58 195.5 0.0 2.1 2 0 0 2 2 2 2 MOZ/SAS family Tudor-knot PF11717.3 CCF54601.1 - 1.2e-11 44.1 0.0 2.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Methyltransf_23 PF13489.1 CCF54602.1 - 1.1e-12 47.9 0.0 2.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54602.1 - 1.4e-12 48.1 0.0 5.2e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54602.1 - 4.4e-12 46.3 0.0 1.1e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF54602.1 - 2.7e-10 40.5 0.0 5.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF54602.1 - 2.9e-07 30.7 0.0 6.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 CCF54602.1 - 5.1e-07 29.4 0.0 7.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 CCF54602.1 - 7.9e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54602.1 - 9.9e-06 25.2 0.0 4.7e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF54602.1 - 0.006 15.9 0.0 0.046 13.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 CCF54602.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 CCF54602.1 - 0.083 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase tRNA_U5-meth_tr PF05958.6 CCF54602.1 - 0.086 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CAP PF00188.21 CCF54603.1 - 6e-26 91.3 3.7 6e-26 91.3 2.6 2.2 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF2413 PF10310.4 CCF54603.1 - 0.23 10.2 7.5 0.27 9.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Collagen PF01391.13 CCF54603.1 - 0.37 10.3 9.1 1.1 8.9 6.3 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF4175 PF13779.1 CCF54603.1 - 0.5 7.9 6.9 0.65 7.6 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) E1-E2_ATPase PF00122.15 CCF54604.1 - 1.3e-57 194.4 0.2 1.3e-57 194.4 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCF54604.1 - 3.1e-24 86.5 0.4 6e-24 85.6 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF54604.1 - 3.8e-16 59.8 0.0 9.8e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCF54604.1 - 1.5e-11 43.5 0.0 3.7e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCF54604.1 - 0.00015 21.4 0.0 0.00085 18.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2404 PF10296.4 CCF54605.1 - 0.0019 18.2 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CRA PF06589.6 CCF54605.1 - 1.5 8.1 4.2 2 7.6 0.5 2.8 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) DnaJ PF00226.26 CCF54606.1 - 1.6e-24 85.4 0.2 3.1e-24 84.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CCF54606.1 - 4.6e-24 84.7 0.2 7.3e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DASH_Dad3 PF08656.5 CCF54607.1 - 0.17 11.5 0.8 0.33 10.6 0.2 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad3 gag_pre-integrs PF13976.1 CCF54608.1 - 2.6e-09 36.5 0.3 5.5e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 CCF54608.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF54609.1 - 1e-19 70.5 0.0 1.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCF54610.1 - 1.4e-15 56.9 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UQ_con PF00179.21 CCF54611.1 - 7e-50 168.1 0.0 8.1e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF54611.1 - 3.3e-07 30.1 0.0 9e-07 28.7 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B HSP70 PF00012.15 CCF54612.1 - 1.4e-260 865.4 8.7 1.5e-260 865.2 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCF54612.1 - 2.8e-12 45.8 8.7 1.2e-11 43.7 0.8 2.8 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 CCF54612.1 - 8.2e-06 25.6 1.2 0.14 11.9 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 CCF54612.1 - 0.008 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MAS20 PF02064.10 CCF54613.1 - 1.6e-17 63.5 0.4 1e-16 60.9 0.3 2.1 1 1 0 1 1 1 1 MAS20 protein import receptor U79_P34 PF03064.11 CCF54613.1 - 0.13 11.7 3.6 0.19 11.2 0.8 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Daxx PF03344.10 CCF54613.1 - 0.45 8.9 13.2 0.67 8.3 9.1 1.2 1 0 0 1 1 1 0 Daxx Family VirionAssem_T7 PF11653.3 CCF54613.1 - 0.47 11.2 17.6 0.1 13.3 3.7 3.2 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein CDC45 PF02724.9 CCF54613.1 - 1.7 6.5 5.8 2.4 6.0 4.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3321 PF11968.3 CCF54614.1 - 1.9e-72 243.4 0.0 2.6e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCF54614.1 - 0.003 17.2 0.0 0.023 14.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain ETF_QO PF05187.8 CCF54615.1 - 1.6e-42 143.9 0.0 3e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 CCF54615.1 - 2.1e-07 30.1 0.5 1e-05 24.5 0.5 2.2 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.19 CCF54615.1 - 1.6e-06 27.2 1.1 0.00062 18.7 0.8 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCF54615.1 - 2.2e-06 27.5 0.6 7.9e-06 25.8 0.0 2.3 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCF54615.1 - 2.5e-05 22.9 0.6 3.9e-05 22.3 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 CCF54615.1 - 0.00012 21.2 0.2 0.00021 20.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCF54615.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCF54615.1 - 0.00025 20.0 0.1 0.00043 19.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCF54615.1 - 0.00081 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCF54615.1 - 0.003 16.6 0.3 0.005 15.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CCF54615.1 - 0.004 16.2 0.1 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCF54615.1 - 0.0046 17.0 0.1 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF54615.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CCF54615.1 - 0.021 13.4 0.7 0.054 12.1 0.5 1.7 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 CCF54615.1 - 0.026 13.3 0.2 0.04 12.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_21 PF14697.1 CCF54615.1 - 0.08 12.8 0.7 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCF54615.1 - 0.086 13.2 1.8 0.19 12.1 1.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 CCF54615.1 - 0.11 12.4 0.5 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_6 PF12837.2 CCF54615.1 - 4 7.4 6.0 0.24 11.3 0.5 1.6 2 0 0 2 2 1 0 4Fe-4S binding domain Barwin PF00967.12 CCF54616.1 - 1.8e-09 37.3 0.2 0.00014 21.5 0.0 2.6 2 0 0 2 2 2 2 Barwin family DPBB_1 PF03330.13 CCF54616.1 - 0.00023 21.1 2.1 0.0022 17.9 0.7 3.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2235 PF09994.4 CCF54616.1 - 0.055 12.8 0.3 3.5 6.9 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hamartin PF04388.7 CCF54616.1 - 1.6 7.3 5.1 1.8 7.1 3.5 1.0 1 0 0 1 1 1 0 Hamartin protein Herpes_UL74 PF07982.7 CCF54616.1 - 2.6 6.6 6.6 5.4 5.6 4.3 1.6 2 0 0 2 2 2 0 Herpes UL74 glycoproteins FYVE PF01363.16 CCF54617.1 - 3.2e-21 75.0 3.8 5.9e-21 74.1 2.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-DHHC PF01529.15 CCF54617.1 - 0.24 10.8 3.3 0.48 9.8 0.6 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase TraG_N PF07916.6 CCF54617.1 - 0.47 8.8 3.3 0.83 8.0 2.3 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DZR PF12773.2 CCF54617.1 - 0.48 10.2 4.7 1.3 8.9 1.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon FYVE_2 PF02318.11 CCF54617.1 - 9.6 6.1 7.7 0.47 10.3 0.3 2.4 3 0 0 3 3 3 0 FYVE-type zinc finger Methyltransf_7 PF03492.10 CCF54618.1 - 5.3e-06 25.4 0.0 0.037 12.7 0.2 2.8 2 1 1 3 3 3 2 SAM dependent carboxyl methyltransferase DUF3670 PF12419.3 CCF54618.1 - 0.047 13.1 0.0 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 Helicase protein WhiA_N PF10298.4 CCF54618.1 - 0.17 11.7 0.4 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain GNAT_acetyltr_2 PF13718.1 CCF54619.1 - 2.7e-74 248.7 0.0 4.5e-74 248.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCF54619.1 - 1.1e-64 217.3 0.0 1.9e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CCF54619.1 - 5e-33 112.6 0.0 1.6e-32 111.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCF54619.1 - 7.7e-27 93.3 2.2 1.6e-26 92.3 0.6 2.3 2 0 0 2 2 2 1 Possible tRNA binding domain TFIIA PF03153.8 CCF54619.1 - 0.00025 21.0 6.9 0.00037 20.5 4.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Acetyltransf_1 PF00583.19 CCF54619.1 - 0.0013 18.7 0.0 0.0042 17.0 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF54619.1 - 0.0013 18.8 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Nop14 PF04147.7 CCF54619.1 - 0.37 8.6 26.3 0.52 8.1 18.2 1.2 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 CCF54619.1 - 0.51 9.8 16.8 1.2 8.6 11.6 1.5 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.8 CCF54619.1 - 0.79 8.1 3.1 2.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Daxx PF03344.10 CCF54619.1 - 1.5 7.1 22.6 2.2 6.6 15.7 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CCF54619.1 - 1.7 7.2 28.4 2.6 6.6 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 CCF54619.1 - 2.2 7.8 18.7 3.1 7.3 11.1 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.9 CCF54619.1 - 3.3 5.6 17.7 5 5.0 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 CCF54619.1 - 7 4.2 29.6 11 3.6 20.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-PARP PF00645.13 CCF54620.1 - 1.2e-21 76.7 0.0 1.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.14 CCF54620.1 - 2.2e-12 45.1 81.8 0.055 13.1 1.8 10.3 10 0 0 10 10 10 9 AT hook motif RNB PF00773.14 CCF54621.1 - 1.4e-101 340.0 0.0 1.4e-101 340.0 0.0 1.7 2 0 0 2 2 2 1 RNB domain Tubulin PF00091.20 CCF54622.1 - 5.3e-69 232.3 0.0 7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCF54622.1 - 1.4e-45 154.3 0.0 2.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCF54622.1 - 0.00045 19.7 0.0 0.0011 18.4 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.22 CCF54623.1 - 2.9e-57 190.3 6.8 8.6e-22 76.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CCF54623.1 - 0.00011 22.2 2.7 0.0067 16.5 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCF54623.1 - 0.00041 19.4 1.9 0.0027 16.8 0.1 3.2 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 CCF54623.1 - 0.0023 17.6 0.1 0.015 15.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain Alpha-E PF04168.7 CCF54625.1 - 0.054 12.8 0.2 0.054 12.8 0.1 1.0 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. SUZ PF12752.2 CCF54625.1 - 1.5 9.4 4.6 2.2 8.8 2.6 1.8 1 1 0 1 1 1 0 SUZ domain Cut8_N PF14482.1 CCF54625.1 - 2 8.4 6.1 9.6 6.2 4.3 1.9 1 1 0 1 1 1 0 Cut8 proteasome-binding domain ADH_zinc_N PF00107.21 CCF54626.1 - 4e-23 81.3 0.0 6.6e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCF54626.1 - 8.4e-11 41.6 0.1 2.1e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCF54626.1 - 0.0002 22.2 0.1 0.00083 20.2 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CCF54626.1 - 0.039 13.5 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 CCF54626.1 - 0.086 12.4 0.2 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 CCF54626.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding XRN_N PF03159.13 CCF54627.1 - 1.9e-103 344.9 0.0 3.1e-103 344.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Lon_C PF05362.8 CCF54628.1 - 2.1e-66 223.1 0.3 4.3e-66 222.1 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CCF54628.1 - 7.7e-33 113.8 0.1 1.8e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CCF54628.1 - 3.5e-21 75.7 0.0 8.9e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CCF54628.1 - 9.6e-07 28.3 0.1 2.6e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CCF54628.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF54628.1 - 1.8e-05 24.7 0.1 0.00043 20.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CCF54628.1 - 3.3e-05 23.8 0.0 8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.6 CCF54628.1 - 7.2e-05 21.6 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 CCF54628.1 - 0.0013 19.5 0.0 0.004 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCF54628.1 - 0.0018 18.3 0.0 0.035 14.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF54628.1 - 0.0024 17.7 0.0 0.0067 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCF54628.1 - 0.009 16.3 2.4 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCF54628.1 - 0.013 14.5 0.0 0.06 12.3 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CCF54628.1 - 0.021 14.2 0.1 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCF54628.1 - 0.04 13.0 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCF54628.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 CCF54628.1 - 0.058 13.2 0.1 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.12 CCF54628.1 - 0.063 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 CCF54628.1 - 0.085 13.1 1.1 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 CCF54628.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCF54628.1 - 0.16 10.6 4.0 0.74 8.4 0.1 2.5 3 0 0 3 3 3 0 TIP49 C-terminus Serglycin PF04360.7 CCF54628.1 - 0.32 10.7 5.2 1.3 8.7 3.6 2.0 1 0 0 1 1 1 0 Serglycin zinc_ribbon_2 PF13240.1 CCF54629.1 - 0.23 10.9 3.6 1.6 8.3 0.4 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.1 CCF54629.1 - 1.5 8.5 6.0 4.3 7.1 4.2 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Zn-ribbon_8 PF09723.5 CCF54629.1 - 4.2 7.4 8.1 8.9 6.3 0.5 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Sgf11 PF08209.6 CCF54629.1 - 5.9 6.2 7.2 3.3 7.1 0.5 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) SR-25 PF10500.4 CCF54630.1 - 0.21 11.0 16.2 0.28 10.6 11.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CCF54630.1 - 0.72 10.1 5.8 0.84 9.9 4.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_S16 PF00886.14 CCF54631.1 - 4.1e-29 100.0 0.1 7e-29 99.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Bax1-I PF01027.15 CCF54632.1 - 6.1e-45 153.3 26.2 7.1e-45 153.1 18.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 CCF54632.1 - 0.64 9.4 14.7 0.37 10.1 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) CMAS PF02353.15 CCF54633.1 - 9.1e-62 208.6 0.3 1.1e-61 208.3 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCF54633.1 - 2.2e-13 50.2 0.1 6.8e-13 48.6 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54633.1 - 2e-10 41.0 0.2 4.5e-09 36.6 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54633.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF54633.1 - 1.2e-06 28.8 0.1 2.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54633.1 - 1e-05 26.0 0.0 2.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF54633.1 - 1.3e-05 25.1 0.0 4.7e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CCF54633.1 - 1.9e-05 24.0 0.0 0.00015 21.1 0.0 2.1 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.9 CCF54633.1 - 8e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CCF54633.1 - 8.5e-05 22.8 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCF54633.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 CCF54633.1 - 0.023 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 CCF54633.1 - 0.09 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 CCF54633.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 CCF54634.1 - 4.4e-58 195.3 0.0 6.2e-58 194.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCF54634.1 - 2.3e-19 69.1 0.0 2.7e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCF54634.1 - 5.7e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCF54634.1 - 0.00043 20.6 0.0 0.0012 19.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCF54634.1 - 0.0015 17.8 0.0 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 CCF54634.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Cytochrom_B562 PF07361.6 CCF54635.1 - 0.09 13.1 1.9 0.27 11.6 1.3 1.8 1 0 0 1 1 1 0 Cytochrome b562 IR1-M PF12185.3 CCF54635.1 - 0.44 10.2 2.6 1.1 9.0 1.8 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF159 PF02586.9 CCF54636.1 - 7.8e-51 172.5 0.0 1.6e-50 171.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_MLP1_2 PF07926.7 CCF54637.1 - 3.5e-21 75.3 17.7 3.5e-21 75.3 12.2 18.0 5 5 7 13 13 13 5 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 CCF54637.1 - 0.0045 17.1 7.0 0.0045 17.1 4.9 15.5 7 5 9 17 17 17 1 Fibrinogen alpha/beta chain family GRASP55_65 PF04495.9 CCF54638.1 - 2.1e-67 225.3 0.0 6.8e-55 184.8 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 CCF54638.1 - 0.042 13.6 0.0 7 6.5 0.0 2.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_2 PF13180.1 CCF54638.1 - 0.063 13.1 0.0 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Mt_ATP-synt_B PF05405.9 CCF54639.1 - 0.057 12.8 0.3 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Spc42p PF11544.3 CCF54639.1 - 0.079 12.8 1.9 0.35 10.8 1.3 2.1 1 0 0 1 1 1 0 Spindle pole body component Spc42p HalX PF08663.5 CCF54639.1 - 0.13 12.2 2.9 0.73 9.8 2.0 2.4 1 1 0 1 1 1 0 HalX domain REV PF00424.13 CCF54640.1 - 0.022 14.6 1.4 0.034 14.0 1.0 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) CCDC144C PF14915.1 CCF54640.1 - 0.029 13.2 0.7 0.036 12.9 0.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4382 PF14321.1 CCF54640.1 - 0.055 13.5 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) SCP2 PF02036.12 CCF54641.1 - 6.1e-11 42.5 0.0 1.6e-10 41.2 0.0 1.7 1 1 1 2 2 2 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 CCF54641.1 - 0.0031 17.4 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal RdRP PF05183.7 CCF54642.1 - 2e-120 403.2 0.0 2.8e-120 402.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF4640 PF15480.1 CCF54642.1 - 0.038 13.5 0.2 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) DUF1779 PF08680.5 CCF54642.1 - 0.11 12.4 0.2 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) Pkinase PF00069.20 CCF54643.1 - 1.1e-36 126.3 0.0 8.7e-36 123.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54643.1 - 1.5e-10 40.6 0.0 8.8e-10 38.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCF54643.1 - 0.00028 20.6 1.2 0.00095 18.9 0.3 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCF54643.1 - 0.0016 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Aminotran_3 PF00202.16 CCF54644.1 - 4.3e-82 275.6 0.0 5.2e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCF54644.1 - 0.0056 15.6 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ThiF PF00899.16 CCF54645.1 - 8.4e-08 32.1 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family RRN7 PF11781.3 CCF54648.1 - 1.1e-05 24.7 0.2 1.9e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Auto_anti-p27 PF06677.7 CCF54648.1 - 0.049 13.4 1.0 0.092 12.5 0.7 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-DHHC PF01529.15 CCF54649.1 - 4.1e-40 136.9 1.2 4.1e-40 136.9 0.8 1.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF1469 PF07332.6 CCF54649.1 - 0.039 13.6 0.3 0.094 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DZR PF12773.2 CCF54649.1 - 4.6 7.1 10.8 0.35 10.7 3.4 2.0 2 0 0 2 2 2 0 Double zinc ribbon RVT_2 PF07727.9 CCF54650.1 - 1e-57 194.9 0.0 1.3e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_23 PF13476.1 CCF54651.1 - 3.3e-26 92.8 0.2 3.3e-26 92.8 0.1 8.2 1 1 3 4 4 4 1 AAA domain AAA_13 PF13166.1 CCF54651.1 - 1.1e-12 47.2 128.7 0.00019 20.0 0.0 6.5 2 1 4 6 6 6 4 AAA domain AAA_21 PF13304.1 CCF54651.1 - 3.2e-12 47.0 10.9 6.3e-09 36.2 0.2 3.8 3 2 1 4 4 4 2 AAA domain SbcCD_C PF13558.1 CCF54651.1 - 1.2e-10 41.2 0.0 3.9e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 CCF54651.1 - 3.5e-10 39.4 15.3 2.9e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCF54651.1 - 0.00083 18.5 14.6 0.00083 18.5 10.1 4.9 1 1 3 5 5 5 2 AAA ATPase domain AAA_29 PF13555.1 CCF54651.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DPM3 PF08285.6 CCF54651.1 - 5.2 6.9 4.7 52 3.7 0.1 4.0 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF719 PF05334.8 CCF54652.1 - 9.5 6.2 8.0 0.24 11.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Cullin PF00888.17 CCF54653.1 - 4.6e-190 633.0 1.7 6.3e-190 632.6 1.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCF54653.1 - 3.9e-28 97.0 5.7 9.8e-28 95.7 1.6 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_27 PF13463.1 CCF54653.1 - 0.0021 18.3 0.6 2 8.8 0.0 3.7 4 0 0 4 4 4 1 Winged helix DNA-binding domain TrmB PF01978.14 CCF54653.1 - 0.12 12.0 2.0 4.9 6.9 0.0 3.8 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB Ubie_methyltran PF01209.13 CCF54654.1 - 6.9e-73 244.6 0.2 5.6e-38 130.3 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCF54654.1 - 1.7e-11 43.9 0.0 3.4e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF54654.1 - 3.5e-11 43.4 0.0 5.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF54654.1 - 1.3e-10 41.1 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54654.1 - 2.6e-10 40.6 0.0 7.1e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54654.1 - 1.2e-07 32.2 0.0 2.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF54654.1 - 8.3e-07 29.3 0.0 1.7e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF54654.1 - 4.7e-06 26.6 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 CCF54654.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 CCF54654.1 - 0.022 14.4 0.0 0.084 12.4 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase MTS PF05175.9 CCF54654.1 - 0.13 11.5 0.1 0.57 9.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain ORC6 PF05460.8 CCF54654.1 - 0.15 11.1 2.8 0.23 10.5 1.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) rpo30_N PF12410.3 CCF54656.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit Thiolase_N PF00108.18 CCF54659.1 - 1.9e-73 246.6 0.5 3.9e-73 245.6 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCF54659.1 - 1.8e-45 153.3 0.5 3e-45 152.6 0.4 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 CCF54659.1 - 6.9e-05 22.7 0.1 0.00024 21.0 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 CCF54659.1 - 0.00013 21.5 1.3 0.00086 18.8 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCF54659.1 - 0.03 13.9 1.9 0.12 12.0 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2093 PF09866.4 CCF54659.1 - 0.12 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) BRCA-2_helical PF09169.5 CCF54659.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 BRCA2, helical Sas10 PF09368.5 CCF54660.1 - 3.5e-27 94.3 3.3 3.5e-27 94.3 2.3 2.4 2 1 1 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CCF54660.1 - 3.9e-09 36.5 0.0 1.5e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 CCF54661.1 - 2.2e-18 66.1 0.3 2.6e-16 59.4 0.1 2.8 2 0 0 2 2 2 2 Fcf2 pre-rRNA processing EPL1 PF10513.4 CCF54662.1 - 7.4e-36 123.8 0.1 7.4e-36 123.8 0.0 7.8 3 1 1 4 4 4 1 Enhancer of polycomb-like CK_II_beta PF01214.13 CCF54663.1 - 1.4e-80 269.1 0.0 1.8e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Pho88 PF10032.4 CCF54664.1 - 3.8e-74 248.0 0.0 4.2e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Tom22 PF04281.8 CCF54665.1 - 4.1e-49 165.6 3.5 4.8e-49 165.4 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Sigma70_ner PF04546.8 CCF54665.1 - 1.8 8.1 7.7 0.13 11.8 1.8 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region ERM PF00769.14 CCF54665.1 - 4.7 6.6 7.8 3.3 7.1 1.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family VWA_2 PF13519.1 CCF54667.1 - 1.2e-10 41.7 0.0 2.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCF54667.1 - 1.1e-08 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Troponin PF00992.15 CCF54667.1 - 0.0058 16.7 0.1 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Troponin Med25_VWA PF11265.3 CCF54667.1 - 0.0062 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.13 CCF54667.1 - 0.2 10.4 0.0 0.59 8.9 0.0 1.7 1 1 0 1 1 1 0 Integrin, beta chain HA2 PF04408.18 CCF54668.1 - 2.7e-29 101.1 0.1 5.5e-29 100.1 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCF54668.1 - 1.1e-23 83.1 0.0 3.7e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCF54668.1 - 2.7e-11 43.1 0.0 5.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCF54668.1 - 1.5e-07 31.0 0.1 3.1e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCF54668.1 - 4.1e-07 30.2 0.0 1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CCF54668.1 - 0.0082 15.9 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCF54668.1 - 0.066 12.9 0.4 0.19 11.4 0.3 1.8 1 1 0 1 1 1 0 Flavivirus DEAD domain Myosin_head PF00063.16 CCF54668.1 - 0.072 11.1 0.0 0.11 10.4 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) SRP54 PF00448.17 CCF54668.1 - 0.078 12.4 0.2 0.23 10.9 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 CCF54668.1 - 0.1 11.8 0.1 0.57 9.3 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein T2SE PF00437.15 CCF54668.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein 3HCDH_N PF02737.13 CCF54669.1 - 7.4e-52 175.6 1.1 1.5e-51 174.6 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CCF54669.1 - 3.1e-32 110.8 0.1 8.8e-32 109.3 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 CCF54669.1 - 6.9e-05 22.6 1.2 0.00017 21.3 0.8 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CCF54669.1 - 0.0018 17.6 1.5 0.0045 16.3 0.4 2.1 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 CCF54669.1 - 0.011 14.7 0.7 0.017 14.1 0.5 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 CCF54669.1 - 0.014 15.2 3.5 0.053 13.3 1.6 2.6 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCF54669.1 - 0.022 15.2 4.5 0.81 10.1 3.1 2.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.6 CCF54669.1 - 0.037 13.1 0.0 0.087 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) DUF1104 PF06518.6 CCF54669.1 - 0.079 13.0 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Paramyxo_P PF01806.12 CCF54669.1 - 0.083 12.1 0.5 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region Herpes_UL32 PF06070.6 CCF54670.1 - 0.31 9.4 7.7 0.36 9.2 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Ribosomal_60s PF00428.14 CCF54670.1 - 3.2 8.2 9.5 4.9 7.6 6.6 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein Prefoldin PF02996.12 CCF54671.1 - 1.3e-26 92.5 3.9 2e-26 92.0 2.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.7 CCF54671.1 - 0.0049 16.6 2.6 0.44 10.3 0.2 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 CCF54671.1 - 0.014 15.3 4.2 0.64 9.8 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Rbsn PF11464.3 CCF54671.1 - 0.014 14.9 2.3 0.014 14.9 1.6 2.0 2 0 0 2 2 2 0 Rabenosyn Rab binding domain DUF1664 PF07889.7 CCF54671.1 - 0.037 13.8 3.4 2.2 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_3 PF13758.1 CCF54671.1 - 0.037 13.8 0.2 0.082 12.6 0.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin_2 PF01920.15 CCF54671.1 - 0.037 13.7 13.6 0.11 12.2 3.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF972 PF06156.8 CCF54671.1 - 0.053 13.8 6.3 0.38 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) XkdW PF09636.5 CCF54671.1 - 0.069 13.0 3.9 0.17 11.7 0.3 2.1 2 0 0 2 2 2 0 XkdW protein Tropomyosin_1 PF12718.2 CCF54671.1 - 0.081 12.7 8.4 0.036 13.9 1.4 2.1 2 0 0 2 2 2 0 Tropomyosin like AIP3 PF03915.8 CCF54671.1 - 0.097 11.5 7.2 0.17 10.7 5.0 1.3 1 1 0 1 1 1 0 Actin interacting protein 3 CENP-Q PF13094.1 CCF54671.1 - 0.18 11.8 13.3 1.1 9.2 0.9 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fib_alpha PF08702.5 CCF54671.1 - 0.24 11.5 5.8 1 9.4 1.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 CCF54671.1 - 0.3 11.0 14.1 0.037 13.9 3.5 2.3 2 0 0 2 2 2 0 FlxA-like protein IncA PF04156.9 CCF54671.1 - 0.33 10.5 9.2 1.5 8.4 0.3 2.0 2 0 0 2 2 2 0 IncA protein DNA_pol3_delt_C PF14840.1 CCF54671.1 - 0.34 11.0 2.6 0.22 11.6 0.5 1.6 2 0 0 2 2 1 0 Processivity clamp loader gamma complex DNA pol III C-term GAS PF13851.1 CCF54671.1 - 0.41 9.8 10.7 0.84 8.8 0.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 CCF54671.1 - 0.54 9.5 7.8 0.52 9.6 1.5 2.1 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) UPF0449 PF15136.1 CCF54671.1 - 0.58 10.3 5.1 9.6 6.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TMPIT PF07851.8 CCF54671.1 - 0.64 9.0 6.4 2.1 7.3 1.7 2.0 2 0 0 2 2 2 0 TMPIT-like protein Dzip-like_N PF13815.1 CCF54671.1 - 0.81 9.5 6.5 0.46 10.3 0.7 2.1 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF948 PF06103.6 CCF54671.1 - 1.1 9.1 5.1 6.4 6.7 0.6 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 CCF54671.1 - 1.2 9.5 12.2 0.22 11.8 3.5 2.3 2 1 0 2 2 2 0 SlyX DUF2508 PF10704.4 CCF54671.1 - 1.5 9.0 7.9 0.67 10.1 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) Mnd1 PF03962.10 CCF54671.1 - 1.5 8.4 8.5 20 4.8 5.9 2.0 1 1 0 1 1 1 0 Mnd1 family Rootletin PF15035.1 CCF54671.1 - 2.2 8.2 10.2 8.6 6.2 0.1 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion RICH PF05062.7 CCF54671.1 - 3.5 7.8 8.0 5.1 7.3 1.5 2.3 2 0 0 2 2 2 0 RICH domain TACC PF05010.9 CCF54671.1 - 6 6.5 10.1 24 4.5 7.0 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF919 PF06034.6 CCF54671.1 - 7.4 6.2 8.1 4.2 7.0 0.2 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) GrpE PF01025.14 CCF54671.1 - 8 5.9 10.1 4 6.9 4.1 2.0 2 0 0 2 2 2 0 GrpE TPR_MLP1_2 PF07926.7 CCF54671.1 - 8.8 6.0 12.2 5.4 6.7 0.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATP-synt_DE_N PF02823.11 CCF54673.1 - 2.1e-18 65.8 0.1 3.3e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ABC_membrane_2 PF06472.10 CCF54675.1 - 1.5e-99 332.6 2.3 2e-99 332.3 1.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCF54675.1 - 2.8e-19 69.7 0.0 6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCF54675.1 - 0.00015 21.8 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCF54675.1 - 0.0054 17.0 0.5 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCF54675.1 - 0.022 13.9 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.10 CCF54675.1 - 0.033 12.8 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_16 PF13191.1 CCF54675.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCF54675.1 - 0.037 13.5 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCF54675.1 - 0.1 12.3 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 CCF54675.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 CCF54675.1 - 0.21 10.2 0.4 0.38 9.3 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PPR_2 PF13041.1 CCF54676.1 - 1.3e-20 73.1 0.0 0.00014 21.7 0.0 7.4 6 2 2 8 8 8 5 PPR repeat family PPR_3 PF13812.1 CCF54676.1 - 3.3e-19 67.4 13.1 0.00091 19.3 0.1 8.6 10 1 0 10 10 10 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCF54676.1 - 7.9e-15 54.0 1.6 0.00041 19.7 0.0 6.6 6 1 0 6 6 6 4 PPR repeat PPR PF01535.15 CCF54676.1 - 6.2e-13 47.7 6.0 0.0021 17.9 0.0 7.2 8 1 0 8 8 8 3 PPR repeat Sec3_C PF09763.4 CCF54677.1 - 3.7e-187 623.6 0.0 4.9e-187 623.2 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CCF54677.1 - 2e-25 88.4 0.2 3.9e-25 87.5 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 CCF54677.1 - 4.6e-06 25.4 0.1 8.8e-06 24.5 0.1 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Ipi1_N PF12333.3 CCF54678.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation rve PF00665.21 CCF54679.1 - 2.5e-13 50.1 0.4 4.6e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 CCF54679.1 - 7.1e-05 21.8 0.0 0.00013 21.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF54679.1 - 0.0084 15.7 0.6 0.024 14.2 0.4 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF500 PF04366.7 CCF54681.1 - 3.5e-42 142.8 0.1 7.2e-42 141.8 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) Glyco_transf_8 PF01501.15 CCF54682.1 - 1.4e-26 93.3 0.0 2.8e-26 92.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 CCF54682.1 - 0.042 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 CCF54682.1 - 0.35 10.1 0.0 0.68 9.2 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Nop14 PF04147.7 CCF54682.1 - 0.69 7.7 5.1 0.96 7.2 3.5 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CCF54682.1 - 1.7 7.8 5.2 2.7 7.1 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.7 CCF54682.1 - 2.6 6.3 13.6 5.3 5.3 9.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CCF54682.1 - 3.8 5.4 6.0 5.9 4.7 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.22 CCF54683.1 - 4.9e-50 170.1 0.1 1e-49 169.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CCF54683.1 - 1.1e-25 89.6 0.0 1.3e-24 86.2 0.0 3.0 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.18 CCF54683.1 - 1.3e-25 90.1 2.6 1.3e-25 90.1 0.1 2.1 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 CCF54683.1 - 9.5e-12 44.1 0.1 2.4e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CCF54683.1 - 0.0049 16.4 0.0 0.035 13.7 0.0 2.5 2 0 0 2 2 2 1 TPR repeat PrkA PF06798.7 CCF54683.1 - 0.089 12.0 0.0 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain MOZART1 PF12554.3 CCF54684.1 - 2.6e-20 71.5 0.5 3e-20 71.3 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 CCF54684.1 - 0.0011 18.9 0.2 0.0017 18.3 0.1 1.4 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain PEP_mutase PF13714.1 CCF54686.1 - 9.2e-42 142.8 0.2 1.1e-41 142.6 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 CCF54686.1 - 7.3e-16 57.4 0.2 1e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family UreF PF01730.11 CCF54687.1 - 6.8e-11 42.4 0.0 1.9e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 UreF CoA_transf_3 PF02515.12 CCF54690.1 - 9e-30 103.3 0.0 1.8e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III DUF3844 PF12955.2 CCF54691.1 - 0.12 12.4 2.2 0.21 11.7 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) DEAD_assoc PF08494.6 CCF54691.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 DEAD/H associated RVT_2 PF07727.9 CCF54692.1 - 4.7e-22 78.1 0.0 6.1e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Oxysterol_BP PF01237.13 CCF54694.1 - 2.3e-116 388.1 0.0 3e-116 387.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CCF54694.1 - 6.8e-16 58.1 1.1 1.4e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCF54694.1 - 6.6e-05 23.0 0.0 0.00023 21.3 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCF54694.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain FAM72 PF14976.1 CCF54696.1 - 2.3e-17 63.2 5.1 6.6e-17 61.7 3.6 1.6 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 CCF54696.1 - 0.0071 16.3 9.7 0.021 14.8 0.1 2.7 2 1 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly IGPD PF00475.13 CCF54697.1 - 6.7e-61 204.4 0.4 1.1e-60 203.7 0.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PLDc_2 PF13091.1 CCF54698.1 - 1.3e-15 57.2 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCF54698.1 - 7.6e-06 25.5 3.1 0.012 15.3 0.1 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif MitMem_reg PF13012.1 CCF54699.1 - 2.4e-36 124.3 0.1 4.6e-36 123.3 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCF54699.1 - 6.8e-28 96.6 0.0 1.2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AAA_11 PF13086.1 CCF54700.1 - 2e-60 204.3 0.0 2e-60 204.3 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 CCF54700.1 - 1.5e-54 184.4 0.0 2.9e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCF54700.1 - 1.8e-10 40.3 2.1 2.5e-10 39.9 0.1 2.3 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 CCF54700.1 - 2.8e-09 36.8 1.3 6.2e-06 25.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 CCF54700.1 - 1.9e-08 34.1 0.1 0.058 12.8 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCF54700.1 - 3.4e-05 23.3 0.2 7.2e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCF54700.1 - 0.00011 22.2 0.1 0.0022 18.1 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 CCF54700.1 - 0.00037 19.9 0.0 0.0012 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCF54700.1 - 0.0011 19.0 0.1 0.012 15.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCF54700.1 - 0.0055 16.7 0.1 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CCF54700.1 - 0.0078 16.4 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CCF54700.1 - 0.017 14.6 0.0 0.066 12.6 0.0 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 CCF54700.1 - 0.017 14.3 0.1 8.2 5.5 0.0 3.3 4 0 0 4 4 4 0 PhoH-like protein DUF2075 PF09848.4 CCF54700.1 - 0.019 13.9 1.7 0.077 11.9 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CCF54700.1 - 0.03 13.9 0.0 1.3 8.6 0.0 2.7 1 1 1 2 2 2 0 Helicase AAA_17 PF13207.1 CCF54700.1 - 0.035 14.9 0.0 0.16 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCF54700.1 - 0.061 13.6 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CCF54700.1 - 0.15 10.6 0.0 0.3 9.6 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IKI3 PF04762.7 CCF54701.1 - 1.4e-286 953.1 0.0 1.8e-286 952.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Lyase_1 PF00206.15 CCF54701.1 - 0.018 14.2 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Lyase Pkinase PF00069.20 CCF54702.1 - 2.8e-67 226.6 0.0 4.2e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54702.1 - 6e-34 117.2 0.0 8.4e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCF54702.1 - 0.0044 16.0 0.0 0.0071 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pol_alpha_B_N PF08418.5 CCF54702.1 - 5.8 6.3 12.0 0.14 11.6 3.1 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L14 PF00238.14 CCF54703.1 - 2.3e-44 150.0 0.9 2.5e-44 149.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MBOAT_2 PF13813.1 CCF54704.1 - 0.001 19.0 2.7 0.0031 17.5 1.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family PPR_2 PF13041.1 CCF54706.1 - 4e-48 161.1 5.0 1.8e-13 50.1 0.0 11.1 7 4 6 13 13 13 8 PPR repeat family PPR_3 PF13812.1 CCF54706.1 - 5.6e-43 141.6 19.7 0.00011 22.1 0.0 14.1 14 0 0 14 14 14 7 Pentatricopeptide repeat domain PPR PF01535.15 CCF54706.1 - 4.2e-41 136.0 8.5 3.4e-06 26.6 0.0 13.0 13 0 0 13 13 13 8 PPR repeat PPR_1 PF12854.2 CCF54706.1 - 2e-32 110.3 0.4 0.00064 19.1 0.0 10.1 10 0 0 10 10 10 5 PPR repeat TPR_14 PF13428.1 CCF54706.1 - 6.2e-08 32.6 19.9 0.55 11.0 0.1 9.6 10 1 1 11 11 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCF54706.1 - 8.4e-08 32.6 9.9 2.4 8.9 0.2 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCF54706.1 - 1.1e-07 32.0 2.2 3.3 8.1 0.0 6.6 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCF54706.1 - 6.3e-06 26.0 16.2 0.25 11.2 0.3 7.2 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCF54706.1 - 2.7e-05 23.6 7.5 1.7 8.6 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCF54706.1 - 0.00064 19.4 12.1 1.1 9.3 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.6 CCF54706.1 - 0.0011 17.8 0.0 0.091 11.6 0.0 3.0 1 1 1 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway SPOB_a PF14689.1 CCF54706.1 - 0.008 15.7 0.5 0.2 11.2 0.0 3.2 4 0 0 4 4 3 1 Sensor_kinase_SpoOB-type, alpha-helical domain Fis1_TPR_C PF14853.1 CCF54706.1 - 0.019 14.8 0.1 4.3 7.2 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 CCF54706.1 - 0.023 14.3 11.6 0.86 9.3 0.3 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCF54706.1 - 0.039 13.6 6.9 6 6.6 0.0 5.8 6 0 0 6 6 6 0 TPR repeat TPR_8 PF13181.1 CCF54706.1 - 0.4 10.5 9.4 19 5.3 0.0 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCF54706.1 - 0.51 10.9 15.0 8.5 7.1 0.1 6.8 7 1 1 8 8 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF54706.1 - 7.5 7.2 7.0 33 5.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat YEATS PF03366.11 CCF54707.1 - 3.9e-32 109.8 0.1 9.6e-32 108.5 0.1 1.6 1 1 0 1 1 1 1 YEATS family Tyrosinase PF00264.15 CCF54708.1 - 4.7e-17 62.9 1.8 7e-17 62.3 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase LURAP PF14854.1 CCF54708.1 - 0.29 10.8 1.4 22 4.7 0.0 2.4 1 1 1 2 2 2 0 Leucine rich adaptor protein RVT_2 PF07727.9 CCF54711.1 - 2e-32 112.1 0.1 3.3e-25 88.4 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF54712.1 - 2.4e-10 40.5 0.1 5.4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 CCF54712.1 - 0.013 15.4 4.3 0.013 15.4 3.0 2.5 2 0 0 2 2 2 0 Zinc knuckle FAD_binding_7 PF03441.9 CCF54714.1 - 3.1e-62 210.2 1.0 5.1e-62 209.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CCF54714.1 - 2.5e-24 85.8 0.0 7.9e-24 84.2 0.0 1.7 1 1 0 1 1 1 1 DNA photolyase 7TMR-DISMED2 PF07696.6 CCF54714.1 - 0.058 12.8 0.3 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 RNA_pol_Rpb2_6 PF00562.23 CCF54715.1 - 1.3e-113 379.6 0.0 1.8e-113 379.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCF54715.1 - 2.5e-28 98.3 0.0 3.5e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 CCF54715.1 - 4.5e-24 84.1 0.0 1.8e-23 82.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 CCF54715.1 - 1.4e-23 82.3 0.0 3.7e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 CCF54715.1 - 7.4e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCF54715.1 - 2.4e-17 62.9 0.1 1.2e-14 54.3 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CCF54715.1 - 3.9e-05 23.5 0.0 8.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Porphobil_deam PF01379.15 CCF54716.1 - 1.4e-67 226.7 0.0 2.5e-63 212.8 0.0 2.4 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCF54716.1 - 1.2e-14 54.1 0.1 1.9e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain YihI PF04220.7 CCF54716.1 - 0.045 13.0 5.7 1.4 8.2 0.3 2.4 2 0 0 2 2 2 0 Der GTPase activator (YihI) WD40 PF00400.27 CCF54717.1 - 2e-08 33.8 0.0 0.17 11.8 0.0 5.4 7 0 0 7 7 7 3 WD domain, G-beta repeat SPT6_acidic PF14632.1 CCF54717.1 - 0.35 11.0 8.8 0.86 9.8 6.1 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 BUD22 PF09073.5 CCF54717.1 - 0.46 9.5 8.7 0.72 8.8 6.0 1.2 1 0 0 1 1 1 0 BUD22 ArsB PF02040.10 CCF54718.1 - 6.9e-12 45.0 14.6 1.6e-07 30.6 1.2 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein FtsJ PF01728.14 CCF54719.1 - 1.1e-38 133.0 0.1 1.5e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pyr_redox_2 PF07992.9 CCF54721.1 - 9.6e-42 143.1 0.4 1.6e-41 142.3 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCF54721.1 - 9.6e-30 102.8 1.8 1.4e-29 102.2 0.7 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCF54721.1 - 3.9e-22 78.4 3.0 1.2e-18 67.2 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCF54721.1 - 1.2e-12 48.3 0.1 4e-05 23.7 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCF54721.1 - 1.1e-06 27.3 2.7 0.011 14.2 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 CCF54721.1 - 0.00011 21.4 0.1 0.00052 19.2 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 CCF54721.1 - 0.0029 16.5 6.3 0.57 9.0 0.0 3.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCF54721.1 - 0.0029 16.5 0.1 0.027 13.3 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCF54721.1 - 0.013 15.5 2.9 0.045 13.7 2.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 CCF54721.1 - 0.054 13.7 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CCF54721.1 - 0.12 12.0 0.6 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CCF54721.1 - 0.64 8.7 6.3 0.17 10.6 1.7 1.9 2 1 0 2 2 2 0 FAD binding domain GIDA PF01134.17 CCF54721.1 - 6.8 5.4 7.4 14 4.4 0.7 3.3 4 1 0 4 4 4 0 Glucose inhibited division protein A FH2 PF02181.18 CCF54722.1 - 5.2e-88 295.4 2.4 3.4e-86 289.4 0.0 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CCF54722.1 - 1.8e-27 95.8 2.7 8e-21 74.2 0.1 3.5 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 CCF54722.1 - 1.7e-19 70.0 0.5 1.7e-19 70.0 0.4 2.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain TMF_DNA_bd PF12329.3 CCF54722.1 - 0.024 14.4 34.6 0.7 9.7 9.9 5.8 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 CCF54722.1 - 0.22 10.1 17.0 0.3 9.7 9.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 CCF54722.1 - 0.74 8.1 16.3 0.026 12.9 1.3 2.2 1 1 1 2 2 2 0 AAA domain TMPIT PF07851.8 CCF54722.1 - 1.6 7.7 3.4 3.4 6.6 2.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein Erp_C PF06780.6 CCF54722.1 - 1.6 8.5 6.0 0.78 9.5 0.1 3.2 3 0 0 3 3 3 0 Erp protein C-terminus Cob_adeno_trans PF01923.13 CCF54722.1 - 2.1 8.1 11.8 0.35 10.6 1.0 3.1 2 1 0 3 3 3 0 Cobalamin adenosyltransferase MRP-S25 PF13741.1 CCF54723.1 - 1e-62 211.6 0.4 1.5e-62 211.0 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CCF54723.1 - 0.0013 18.6 1.0 1.4 8.7 0.1 2.5 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 RNase_PH PF01138.16 CCF54724.1 - 1.1e-11 45.2 0.3 1.5e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCF54724.1 - 2.1e-09 37.1 0.0 8.6e-08 32.0 0.0 2.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 Methyltransf_23 PF13489.1 CCF54725.1 - 1.1e-14 54.4 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54725.1 - 9.2e-14 51.7 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54725.1 - 3.7e-09 36.3 0.0 6.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCF54725.1 - 8.2e-09 34.9 0.0 1.3e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CCF54725.1 - 1e-07 32.3 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54725.1 - 1.9e-07 31.6 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCF54725.1 - 4.3e-07 30.2 0.0 8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF54725.1 - 3.2e-06 27.1 0.0 7.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF54725.1 - 2.9e-05 23.5 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 CCF54725.1 - 0.043 12.8 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.10 CCF54725.1 - 0.29 10.7 0.0 0.66 9.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Skp1_POZ PF03931.10 CCF54726.1 - 8.4e-07 28.9 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Glyco_hydro_18 PF00704.23 CCF54726.1 - 0.068 12.6 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Myb_DNA-bind_6 PF13921.1 CCF54727.1 - 0.015 15.4 0.5 0.1 12.6 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain UQ_con PF00179.21 CCF54728.1 - 1.1e-52 177.2 0.0 1.2e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCF54728.1 - 5e-05 23.0 0.0 6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCF54728.1 - 0.00061 19.6 0.0 0.00074 19.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CCF54728.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Herpes_gE PF02480.11 CCF54730.1 - 0.017 13.4 0.0 0.032 12.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MRP-L20 PF12824.2 CCF54730.1 - 0.039 13.9 2.4 0.11 12.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 MtrF PF09472.5 CCF54730.1 - 0.24 10.6 1.2 0.63 9.3 0.8 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) TMEM154 PF15102.1 CCF54730.1 - 0.41 10.3 0.3 2.8 7.6 0.2 2.5 1 1 0 1 1 1 0 TMEM154 protein family Tweety PF04906.8 CCF54730.1 - 0.52 8.6 0.0 0.79 8.0 0.0 1.1 1 0 0 1 1 1 0 Tweety Glyco_tran_28_C PF04101.11 CCF54732.1 - 5.9e-21 74.8 0.0 6.2e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain MOSC_N PF03476.11 CCF54733.1 - 5.7e-19 68.0 0.0 1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 CCF54733.1 - 4.8e-09 35.7 0.0 3.3e-07 29.8 0.0 2.6 1 1 0 1 1 1 1 MOSC domain Filament PF00038.16 CCF54734.1 - 0.0016 17.9 21.0 0.0025 17.3 14.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein Csm1 PF12539.3 CCF54734.1 - 0.0058 17.0 0.1 0.031 14.7 0.0 2.3 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF2450 PF10475.4 CCF54734.1 - 0.24 10.2 6.4 1.2 7.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Fzo_mitofusin PF04799.8 CCF54734.1 - 0.44 9.9 6.4 1.2 8.4 0.8 2.3 2 0 0 2 2 2 0 fzo-like conserved region BLOC1_2 PF10046.4 CCF54734.1 - 1.7 8.8 12.6 1 9.5 0.3 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_lysis PF03245.8 CCF54734.1 - 4.3 7.3 19.6 0.2 11.6 7.3 3.0 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Ras PF00071.17 CCF54735.1 - 4e-58 195.3 0.1 4.8e-58 195.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF54735.1 - 2.6e-20 73.0 0.1 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF54735.1 - 3.9e-09 35.9 0.0 4.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCF54735.1 - 4.8e-07 29.3 0.0 9.1e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF54735.1 - 0.0046 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF54735.1 - 0.0079 15.4 0.0 0.021 14.1 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CCF54735.1 - 0.019 14.5 1.4 0.23 10.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 CCF54735.1 - 0.035 13.2 0.1 0.051 12.6 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ser_hydrolase PF06821.8 CCF54735.1 - 0.067 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase MRC1 PF09444.5 CCF54736.1 - 0.46 10.8 3.7 0.66 10.2 2.5 1.3 1 0 0 1 1 1 0 MRC1-like domain GDA1_CD39 PF01150.12 CCF54738.1 - 1.8e-99 333.2 0.0 2.6e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family zf-CCCH PF00642.19 CCF54739.1 - 0.0041 16.7 2.1 0.0041 16.7 1.4 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AICARFT_IMPCHas PF01808.13 CCF54739.1 - 0.0072 15.4 0.1 0.017 14.2 0.1 1.6 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme PTPS PF01242.14 CCF54739.1 - 0.11 12.2 1.8 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase Tyr-DNA_phospho PF06087.7 CCF54740.1 - 1.5e-24 86.4 0.0 1.3e-23 83.3 0.0 2.1 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CCF54740.1 - 0.011 15.4 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain IncA PF04156.9 CCF54742.1 - 0.088 12.3 24.1 0.024 14.2 6.7 2.5 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 CCF54742.1 - 0.24 11.7 11.4 1.7 9.0 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Bacillus_HBL PF05791.6 CCF54742.1 - 0.29 10.4 1.3 0.61 9.4 0.1 2.1 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 CCF54742.1 - 3.6 7.1 17.7 1 8.8 4.9 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CCF54742.1 - 8.7 4.0 7.9 9.3 3.9 0.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DSPc PF00782.15 CCF54743.1 - 1.5e-27 95.8 0.0 2.5e-18 65.9 0.0 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCF54743.1 - 2.1e-05 23.9 0.0 0.00074 18.9 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2924 PF11149.3 CCF54743.1 - 0.03 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) AIRC PF00731.15 CCF54745.1 - 1.6e-64 215.6 2.7 4.1e-64 214.3 1.9 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CCF54745.1 - 1.3e-55 187.4 0.3 4.3e-55 185.6 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCF54745.1 - 1.1e-12 48.0 0.1 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCF54745.1 - 0.00056 19.3 0.0 0.0044 16.4 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.13 CCF54745.1 - 0.0078 15.8 0.0 0.026 14.1 0.1 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCF54745.1 - 0.011 15.7 0.4 0.064 13.2 0.1 2.3 2 0 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 CCF54745.1 - 0.028 13.6 0.1 0.079 12.1 0.1 1.8 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 CCF54745.1 - 0.047 12.8 0.4 0.16 11.0 0.1 2.1 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 CCF54745.1 - 0.054 13.6 0.8 13 5.9 0.1 3.1 2 1 1 3 3 3 0 CoA binding domain CBS PF00571.23 CCF54746.1 - 1.3e-06 28.1 0.0 0.0054 16.4 0.0 4.0 4 0 0 4 4 4 2 CBS domain DASH_Ask1 PF08655.5 CCF54747.1 - 1.2e-29 101.9 0.1 2.2e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 CDC45 PF02724.9 CCF54747.1 - 3.7 5.4 9.9 0.72 7.8 3.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Pex24p PF06398.6 CCF54748.1 - 1.4e-06 27.3 6.0 2.3e-06 26.6 4.2 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin IF-2B PF01008.12 CCF54749.1 - 1.3e-58 198.1 0.1 2.2e-52 177.8 0.0 2.0 2 0 0 2 2 2 2 Initiation factor 2 subunit family Gly-rich_Ago1 PF12764.2 CCF54749.1 - 0.92 10.1 7.5 0.32 11.6 1.4 2.8 2 1 0 2 2 2 0 Glycine-rich region of argonaut SAM_decarbox PF01536.11 CCF54751.1 - 5.7e-78 261.8 0.0 1.5e-44 152.0 0.0 2.9 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase FA_desaturase PF00487.19 CCF54751.1 - 0.019 14.4 3.7 0.037 13.4 2.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase ThiF PF00899.16 CCF54752.1 - 1.7e-41 141.2 0.3 6.1e-40 136.1 0.0 2.5 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 CCF54752.1 - 3.4e-27 93.7 0.3 9.1e-27 92.4 0.2 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCF54752.1 - 1.1e-21 75.9 2.6 2e-21 75.0 1.8 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CCF54752.1 - 3.9e-17 62.1 1.6 1.1e-16 60.6 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 CCF54752.1 - 0.00031 20.9 0.4 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCF54752.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase EF-1_beta_acid PF10587.4 CCF54752.1 - 0.0065 16.5 1.7 0.0065 16.5 1.2 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region VHS PF00790.14 CCF54753.1 - 2.4e-41 140.6 0.0 6.6e-41 139.2 0.0 1.8 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 CCF54753.1 - 3.8e-22 78.1 0.4 9.9e-22 76.8 0.3 1.7 1 0 0 1 1 1 1 GAT domain FHA PF00498.21 CCF54754.1 - 0.0083 16.2 0.1 0.019 15.1 0.1 1.6 1 1 0 1 1 1 1 FHA domain Citrate_synt PF00285.16 CCF54755.1 - 6.7e-17 61.2 0.1 9.8e-15 54.1 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 CCF54755.1 - 6.2e-16 58.3 0.1 1.2e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 CCF54755.1 - 2e-12 47.4 0.0 6.3e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 CCF54755.1 - 5.8e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 CCF54755.1 - 1.5e-06 27.8 0.0 6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 CCF54755.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain NAD_binding_10 PF13460.1 CCF54756.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CCF54756.1 - 0.017 15.3 0.0 0.045 14.0 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 CCF54756.1 - 0.029 13.3 0.0 0.29 10.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.16 CCF54756.1 - 0.059 12.7 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Asparaginase PF00710.15 CCF54757.1 - 3.7e-144 479.3 0.0 4.7e-144 479.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 CCF54757.1 - 1.3e-11 44.7 0.0 3.5e-11 43.2 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCF54757.1 - 3.8e-10 39.0 0.1 3.6e-06 26.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCF54757.1 - 9.3e-06 25.7 0.0 0.00038 20.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCF54757.1 - 0.00032 20.6 0.1 0.13 12.6 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CCF54757.1 - 0.00049 20.5 0.1 0.0055 17.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF1744 PF08490.7 CCF54758.1 - 8.5e-120 399.9 0.0 1.3e-119 399.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCF54758.1 - 8.8e-64 215.4 0.0 1.7e-63 214.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCF54758.1 - 3e-22 79.0 0.1 1.3e-21 76.9 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCF54758.1 - 2.3e-10 40.3 0.0 5.9e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCF54758.1 - 8.8e-06 25.6 0.0 3.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily Glycogen_syn PF05693.8 CCF54759.1 - 0 1103.8 0.0 0 1103.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 CCF54759.1 - 2e-08 34.0 0.5 1.4e-07 31.2 0.3 2.2 1 1 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CCF54759.1 - 2.2e-08 33.7 0.0 3.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCF54759.1 - 9.2e-07 29.1 0.4 1.8e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain gpUL132 PF11359.3 CCF54760.1 - 0.036 13.3 0.1 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF2262 PF10020.4 CCF54760.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DBR1 PF05011.8 CCF54761.1 - 2.6e-23 82.5 0.0 1.3e-15 57.5 0.0 2.5 1 1 1 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CCF54761.1 - 2.7e-09 36.7 0.1 7.5e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCF54761.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RA PF00788.18 CCF54762.1 - 1.2e-11 44.9 0.0 2.8e-08 34.1 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 CCF54762.1 - 1.7e-07 30.5 0.0 3.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCF54762.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain La PF05383.12 CCF54763.1 - 1.2e-17 63.3 0.0 2.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 La domain DUF3136 PF11334.3 CCF54765.1 - 0.11 11.9 0.3 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) E1-E2_ATPase PF00122.15 CCF54766.1 - 1.6e-35 122.2 0.0 3e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCF54766.1 - 3.2e-28 99.6 0.0 5.8e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCF54766.1 - 4.1e-15 56.4 0.0 8.5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCF54766.1 - 2.3e-14 53.2 12.7 2.2e-06 27.6 0.2 4.5 4 1 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.7 CCF54766.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Transcrip_reg PF01709.15 CCF54766.1 - 0.16 11.0 0.1 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Pro_isomerase PF00160.16 CCF54768.1 - 4.3e-44 150.4 0.1 5.1e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3336 PF11815.3 CCF54769.1 - 2.4e-42 143.9 2.6 3.9e-42 143.1 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCF54769.1 - 4e-20 72.6 0.2 1.1e-19 71.2 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase DUF2361 PF10153.4 CCF54770.1 - 9.8e-21 74.0 9.4 9.8e-21 74.0 6.5 2.9 2 2 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) RXT2_N PF08595.6 CCF54770.1 - 0.027 14.2 13.3 0.036 13.8 2.1 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 CCF54770.1 - 1.9 8.0 12.8 2.2 7.7 2.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin ANAPC15 PF15243.1 CCF54770.1 - 3.5 7.7 15.9 2.5 8.2 3.3 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 6PF2K PF01591.13 CCF54771.1 - 1.5e-62 210.6 0.0 2.3e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCF54771.1 - 2.1e-22 79.9 0.0 4.7e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CCF54771.1 - 0.0032 18.2 0.1 0.016 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCF54771.1 - 0.024 14.4 0.0 0.066 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 CCF54772.1 - 1.4e-22 79.3 0.0 1.7e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCF54772.1 - 0.00056 19.9 0.1 0.0018 18.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCF54772.1 - 0.012 15.7 0.0 0.064 13.4 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_4 PF13462.1 CCF54772.1 - 0.076 13.0 0.0 0.18 11.8 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.1 CCF54772.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin CRC_subunit PF08624.5 CCF54773.1 - 2.8e-46 156.8 0.3 6.4e-46 155.7 0.0 1.7 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit GxGYxYP PF14323.1 CCF54774.1 - 0.039 12.6 0.0 0.067 11.8 0.0 1.3 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Zn_clus PF00172.13 CCF54775.1 - 3.3e-10 39.7 7.2 5.5e-10 38.9 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 CCF54776.1 - 1.5e-21 76.7 0.0 2.5e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CCF54776.1 - 8.7e-17 60.3 12.5 6.1e-10 38.6 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 CCF54776.1 - 8.4e-13 47.2 4.7 0.01 15.8 0.0 7.3 7 0 0 7 7 7 4 HEAT repeat Pkinase_Tyr PF07714.12 CCF54776.1 - 3e-09 36.3 0.0 2.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 CCF54776.1 - 9.5e-07 29.0 4.5 0.069 13.4 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats Kinase-like PF14531.1 CCF54776.1 - 0.00088 18.3 0.0 0.093 11.6 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Nucleoporin_N PF08801.6 CCF54776.1 - 0.003 16.3 0.0 0.029 13.1 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like Kdo PF06293.9 CCF54776.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2435 PF10363.4 CCF54776.1 - 0.13 12.2 0.5 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 CCF54776.1 - 0.56 10.0 0.5 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CNH PF00780.17 CCF54777.1 - 1.1e-65 221.8 0.0 1.7e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 CCF54777.1 - 5.3e-31 107.8 0.0 8.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 CCF54777.1 - 6.4e-09 35.8 0.0 3.6e-05 23.7 0.0 3.1 2 0 0 2 2 2 2 Pleckstrin homology domain DEP PF00610.16 CCF54777.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Acetyltransf_1 PF00583.19 CCF54778.1 - 3e-13 49.6 0.0 6.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCF54778.1 - 9.5e-08 32.1 0.7 4e-07 30.1 0.1 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCF54778.1 - 5.5e-05 22.8 0.1 0.0064 16.2 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 CCF54778.1 - 0.00071 19.6 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCF54778.1 - 0.0044 16.9 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCF54778.1 - 0.02 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 CCF54778.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.1 CCF54778.1 - 0.054 13.3 0.3 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCF54778.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPT2 PF08243.6 CCF54779.1 - 4.9e-17 62.2 17.4 4.9e-17 62.2 12.1 4.9 5 2 0 5 5 5 1 SPT2 chromatin protein PRMT5 PF05185.11 CCF54780.1 - 4.1e-151 503.9 0.0 5.3e-151 503.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 CCF54780.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CS PF04969.11 CCF54781.1 - 6.2e-07 29.8 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 CS domain Virulence_fact PF13769.1 CCF54781.1 - 0.14 12.0 0.3 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Virulence factor RhoGAP PF00620.22 CCF54782.1 - 1.5e-44 151.2 0.1 2.4e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CCF54782.1 - 1.4e-13 50.9 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 PH domain PX PF00787.19 CCF54782.1 - 1.8e-07 30.9 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_7 PF15408.1 CCF54782.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain UPF0047 PF01894.12 CCF54783.1 - 4.9e-40 136.0 0.0 5.4e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 RVT_2 PF07727.9 CCF54785.1 - 1e-39 135.9 0.0 1.2e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATA PF00320.22 CCF54787.1 - 1e-30 104.7 18.1 2e-15 55.8 4.7 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCF54787.1 - 9.1e-06 24.9 5.8 0.023 14.0 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 CCF54787.1 - 0.0029 17.0 5.8 0.54 9.8 0.3 2.4 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 CCF54787.1 - 0.055 13.4 1.9 3.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain ArfGap PF01412.13 CCF54787.1 - 0.2 11.4 4.3 4.6 7.0 0.2 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 CCF54787.1 - 0.27 10.5 6.2 5.2 6.4 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCF54787.1 - 0.31 10.7 1.2 8.3 6.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCF54787.1 - 0.33 10.5 1.2 6.5 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 CCF54787.1 - 0.49 10.0 5.6 1.2 8.8 0.2 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 CCF54787.1 - 0.59 9.7 12.3 0.55 9.8 0.4 3.3 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Auto_anti-p27 PF06677.7 CCF54787.1 - 1.6 8.5 3.7 26 4.6 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Acyl-CoA_dh_1 PF00441.19 CCF54788.1 - 1.1e-48 165.1 3.9 1.9e-48 164.3 2.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CCF54788.1 - 1.8e-26 92.9 0.2 3.8e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CCF54788.1 - 9.3e-24 82.7 0.3 2e-23 81.6 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CCF54788.1 - 8.5e-16 58.4 4.1 2.1e-15 57.1 2.8 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CCF54788.1 - 7.5e-05 22.2 0.7 0.00033 20.1 0.5 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Orn_Arg_deC_N PF02784.11 CCF54789.1 - 3.2e-70 236.1 0.0 4.4e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCF54789.1 - 4.6e-30 103.7 0.0 7.2e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 CCF54789.1 - 0.031 13.5 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PB1-F2 PF11986.3 CCF54790.1 - 0.052 13.5 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Influenza A Proapoptotic protein DUF3622 PF12286.3 CCF54790.1 - 0.09 13.0 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) RVT_2 PF07727.9 CCF54791.1 - 1.6e-18 66.5 0.0 2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FA_desaturase PF00487.19 CCF54793.1 - 4.5e-24 85.2 25.8 1.8e-23 83.3 17.9 2.0 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 CCF54793.1 - 0.00012 22.1 0.1 0.00021 21.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF1604 PF07713.8 CCF54794.1 - 1.3e-35 120.9 4.1 3.5e-35 119.6 2.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 CCF54794.1 - 2.8e-06 26.9 2.4 2.8e-06 26.9 1.6 2.0 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CCF54794.1 - 0.26 11.1 5.9 0.16 11.8 1.7 2.6 2 1 0 2 2 2 0 DExH-box splicing factor binding site Fork_head PF00250.13 CCF54796.1 - 6.6e-31 106.2 0.1 6.6e-31 106.2 0.1 1.9 2 0 0 2 2 2 1 Fork head domain Aminotran_3 PF00202.16 CCF54797.1 - 1.5e-103 346.2 0.1 1.8e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCF54797.1 - 4.4e-05 22.5 0.0 0.00076 18.5 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II NAD_binding_9 PF13454.1 CCF54798.1 - 5.4e-05 23.0 0.0 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCF54798.1 - 0.026 14.5 0.0 6.4 6.7 0.0 2.7 1 1 2 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCF54798.1 - 0.049 13.5 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCF54798.1 - 0.094 11.6 0.1 8.8 5.1 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) CDP-OH_P_transf PF01066.16 CCF54799.1 - 6.6e-15 55.2 2.8 6.6e-15 55.2 1.9 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PLA2_B PF01735.13 CCF54800.1 - 1.7e-127 425.5 11.8 4.2e-98 328.6 2.9 2.2 1 1 1 2 2 2 2 Lysophospholipase catalytic domain Actin PF00022.14 CCF54801.1 - 7.4e-94 314.3 0.0 9.1e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 Actin Tom37_C PF11801.3 CCF54802.1 - 2.7 7.8 6.0 12 5.7 4.2 2.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DPBB_1 PF03330.13 CCF54803.1 - 1.3e-10 41.0 0.0 2.4e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 CCF54803.1 - 0.0016 18.1 2.2 0.0047 16.5 0.1 2.1 1 1 1 2 2 2 1 Barwin family AICARFT_IMPCHas PF01808.13 CCF54804.1 - 1e-110 369.7 0.1 1.6e-110 369.0 0.1 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCF54804.1 - 1e-21 76.6 0.0 2.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Phage_int_SAM_1 PF02899.12 CCF54804.1 - 0.051 13.7 0.3 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain FAD-oxidase_C PF02913.14 CCF54805.1 - 4.5e-52 176.8 0.0 6.9e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCF54805.1 - 2.3e-32 111.3 0.0 3.9e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3918 PF13056.1 CCF54805.1 - 0.023 13.9 0.3 0.049 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) TPT PF03151.11 CCF54806.1 - 1.5e-11 44.1 5.1 1.5e-11 44.1 3.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCF54806.1 - 5.2e-10 38.7 14.5 7.1e-07 28.4 1.1 2.1 2 0 0 2 2 2 2 UAA transporter family Polysacc_synt_4 PF04669.8 CCF54807.1 - 5.4e-28 97.6 2.2 3.1e-27 95.1 1.5 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis AAA PF00004.24 CCF54808.1 - 6.3e-97 320.8 0.0 4.6e-47 159.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCF54808.1 - 2.8e-21 75.2 0.4 1.3e-20 73.1 0.1 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 CCF54808.1 - 4.3e-14 52.1 0.1 6.2e-06 25.4 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCF54808.1 - 8.3e-13 48.4 0.0 3.2e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCF54808.1 - 1.7e-12 47.5 0.0 2.7e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCF54808.1 - 1e-11 44.7 0.4 4.1e-06 26.5 0.0 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCF54808.1 - 2.2e-11 44.6 0.0 0.00047 20.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CCF54808.1 - 2.4e-11 43.0 0.0 5.8e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 CCF54808.1 - 3.6e-11 43.3 0.2 0.0024 18.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCF54808.1 - 1.7e-10 41.1 0.0 0.0013 18.7 0.0 3.3 2 2 1 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 CCF54808.1 - 2.8e-09 36.1 0.1 0.0012 17.6 0.0 2.5 2 1 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CCF54808.1 - 2e-08 33.8 2.1 0.0083 15.5 0.0 3.6 2 2 1 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CCF54808.1 - 5.8e-08 32.0 0.0 0.0085 15.2 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CCF54808.1 - 6.2e-08 32.2 0.0 0.004 16.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCF54808.1 - 9.4e-08 31.7 1.5 0.0076 15.9 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 CCF54808.1 - 1.7e-07 30.6 0.3 0.012 14.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCF54808.1 - 1.8e-07 31.1 0.0 0.0036 17.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCF54808.1 - 4.6e-07 29.9 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 CCF54808.1 - 7.5e-07 28.4 0.8 0.43 9.6 0.0 3.4 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 CCF54808.1 - 2.9e-06 26.3 0.1 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CCF54808.1 - 3.5e-06 27.3 0.0 0.035 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 CCF54808.1 - 4.4e-06 26.4 0.1 0.12 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 CCF54808.1 - 6.4e-06 26.1 0.0 0.005 16.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CCF54808.1 - 8.3e-06 25.8 0.5 0.11 12.4 0.0 3.0 4 0 0 4 4 2 2 AAA domain DUF815 PF05673.8 CCF54808.1 - 1.3e-05 24.2 0.0 0.008 15.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 CCF54808.1 - 1.3e-05 24.7 0.0 0.28 10.6 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 CCF54808.1 - 2.1e-05 24.3 0.0 0.00014 21.6 0.0 2.4 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.1 CCF54808.1 - 2.4e-05 24.4 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 CCF54808.1 - 2.4e-05 24.0 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein ABC_tran PF00005.22 CCF54808.1 - 4.1e-05 23.9 0.0 0.2 11.9 0.0 3.5 2 1 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 CCF54808.1 - 4.3e-05 23.3 0.0 2.6 7.6 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 CCF54808.1 - 4.9e-05 22.6 0.2 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 CCF54808.1 - 0.00014 21.5 0.1 0.52 9.9 0.0 3.5 4 0 0 4 4 3 1 NACHT domain AAA_3 PF07726.6 CCF54808.1 - 0.00015 21.3 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 CCF54808.1 - 0.00034 20.2 0.0 0.53 9.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CCF54808.1 - 0.00035 19.6 0.0 0.38 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCF54808.1 - 0.00088 18.9 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCF54808.1 - 0.001 18.0 0.1 0.33 9.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 CCF54808.1 - 0.0042 16.8 0.3 1.2 8.8 0.0 3.3 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 CCF54808.1 - 0.0049 16.4 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Molydop_binding PF01568.16 CCF54808.1 - 0.0075 16.0 0.0 0.079 12.7 0.0 2.5 1 1 1 2 2 2 1 Molydopterin dinucleotide binding domain T2SE PF00437.15 CCF54808.1 - 0.011 14.6 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 CCF54808.1 - 0.035 13.7 0.1 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CCF54808.1 - 0.036 13.0 0.0 0.61 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain IPT PF01745.11 CCF54808.1 - 0.039 13.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 CCF54808.1 - 0.054 12.9 0.1 12 5.2 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DEAD PF00270.24 CCF54808.1 - 0.081 12.4 0.2 27 4.1 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase CCDC14 PF15254.1 CCF54808.1 - 0.096 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 KTI12 PF08433.5 CCF54808.1 - 0.13 11.4 0.0 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 CCF54808.1 - 0.13 12.0 1.0 7.8 6.3 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase PIF1 PF05970.9 CCF54808.1 - 0.15 10.9 0.1 6.2 5.6 0.0 2.9 4 0 0 4 4 3 0 PIF1-like helicase AAA_10 PF12846.2 CCF54808.1 - 0.16 11.3 0.7 5.3 6.3 0.0 3.3 3 1 1 4 4 4 0 AAA-like domain PPV_E1_C PF00519.12 CCF54808.1 - 0.32 9.5 0.0 3.2 6.2 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase MobB PF03205.9 CCF54808.1 - 0.47 10.1 1.9 9.6 5.9 0.0 3.5 5 0 0 5 5 3 0 Molybdopterin guanine dinucleotide synthesis protein B SHR3_chaperone PF08229.6 CCF54809.1 - 2.9e-39 134.0 0.7 5.8e-39 133.0 0.5 1.5 1 1 0 1 1 1 1 ER membrane protein SH3 Neurensin PF14927.1 CCF54809.1 - 0.6 9.4 2.8 6 6.2 2.0 2.3 1 1 0 1 1 1 0 Neurensin Clat_adaptor_s PF01217.15 CCF54810.1 - 3.3e-49 166.2 0.4 5.8e-36 123.3 0.3 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Mito_carr PF00153.22 CCF54811.1 - 5.7e-71 234.3 5.1 1.5e-23 82.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.1 CCF54811.1 - 0.081 12.2 0.1 0.18 11.1 0.0 1.5 1 1 0 1 1 1 0 Penicillin-binding protein Tp47 domain a NRDD PF13597.1 CCF54811.1 - 0.12 10.3 0.5 0.21 9.6 0.4 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Ribosomal_S13 PF00416.17 CCF54812.1 - 4.1e-40 136.5 1.6 4.9e-40 136.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCF54812.1 - 0.0029 16.2 0.0 0.004 15.7 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCF54812.1 - 0.07 13.1 0.2 0.2 11.7 0.1 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif CPSase_L_D2 PF02786.12 CCF54814.1 - 8.7e-82 273.4 0.1 1.4e-81 272.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCF54814.1 - 1.6e-67 226.7 0.0 2.9e-67 225.9 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCF54814.1 - 1.5e-35 121.6 0.0 6.1e-35 119.6 0.0 2.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain HMGL-like PF00682.14 CCF54814.1 - 6.3e-31 107.8 0.0 1.1e-30 107.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 CCF54814.1 - 1e-29 102.6 0.0 2.1e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCF54814.1 - 3.7e-20 72.4 0.1 6.7e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCF54814.1 - 2.5e-16 59.0 0.9 5.1e-16 58.0 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCF54814.1 - 1.4e-15 56.9 0.0 4.1e-15 55.3 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CCF54814.1 - 2.3e-15 55.9 0.3 1.5e-06 27.7 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CCF54814.1 - 3.3e-09 36.4 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 CCF54814.1 - 8.4e-09 35.1 0.1 0.0035 16.6 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 CCF54814.1 - 2.8e-07 30.0 0.0 5.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCF54814.1 - 1e-05 25.1 0.0 4.2e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCF54814.1 - 8.1e-05 22.5 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCF54814.1 - 0.00044 19.8 0.0 0.00084 18.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.1 CCF54814.1 - 0.00075 19.8 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 CCF54814.1 - 0.007 15.5 0.1 0.096 11.8 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein NQRA PF05896.6 CCF54814.1 - 0.014 14.6 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PNPase PF03726.9 CCF54814.1 - 0.46 10.7 2.0 0.52 10.6 0.2 2.0 2 0 0 2 2 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain MFS_1 PF07690.11 CCF54816.1 - 4.4e-33 114.4 32.9 2.1e-31 108.9 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF54816.1 - 1.4e-10 40.3 23.1 2.3e-10 39.6 16.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CCF54816.1 - 0.0039 15.4 5.3 0.0072 14.5 3.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SURF1 PF02104.10 CCF54818.1 - 4e-46 157.5 0.0 6.2e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 SURF1 family UAA PF08449.6 CCF54819.1 - 1.9e-72 243.7 6.1 2.1e-71 240.3 4.2 1.9 1 1 0 1 1 1 1 UAA transporter family DUF1109 PF06532.6 CCF54819.1 - 0.00088 18.7 0.6 0.0028 17.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1109) Metallophos PF00149.23 CCF54821.1 - 2.4e-07 30.3 3.8 6.5e-07 28.9 2.7 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase IPK PF03770.11 CCF54822.1 - 7.5e-50 169.3 0.0 1.3e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Kelch_4 PF13418.1 CCF54823.1 - 2.3e-13 49.6 0.2 0.0015 18.2 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CCF54823.1 - 8.1e-13 47.9 0.4 0.0055 16.8 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 CCF54823.1 - 2e-08 34.0 0.1 0.0017 18.2 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CCF54823.1 - 2.8e-08 33.6 3.8 3.9e-06 26.8 0.0 5.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CCF54823.1 - 3.5e-05 23.3 0.1 3.6 7.5 0.0 4.8 4 1 0 4 4 4 2 Kelch motif CDV3 PF15359.1 CCF54823.1 - 0.048 13.7 7.9 1.4 8.9 0.0 3.3 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Kelch_1 PF01344.20 CCF54823.1 - 0.072 12.6 0.0 21 4.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif AMP-binding PF00501.23 CCF54825.1 - 1.6e-77 260.6 0.0 2.5e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCF54825.1 - 6.4e-07 30.2 0.2 1.4e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNase_PH PF01138.16 CCF54826.1 - 3e-31 108.4 0.1 6.4e-31 107.4 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCF54826.1 - 0.0022 17.9 0.1 0.0061 16.4 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Cullin PF00888.17 CCF54827.1 - 3.8e-30 104.9 0.0 4.2e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 Cullin family NBP1 PF08537.5 CCF54827.1 - 0.051 12.7 3.0 0.082 12.1 2.1 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Proteasome PF00227.21 CCF54828.1 - 4.8e-33 114.0 0.0 1.1e-32 112.8 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Condensation PF00668.15 CCF54829.1 - 0.0099 14.7 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Condensation domain AATase PF07247.7 CCF54829.1 - 0.11 11.0 0.0 9.9 4.5 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase HTH_10 PF04967.7 CCF54830.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 HTH DNA binding domain TLV_coat PF00429.14 CCF54830.1 - 0.23 9.8 0.0 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) DUF3712 PF12505.3 CCF54832.1 - 1.4e-103 341.7 39.4 3.6e-22 78.7 0.0 8.8 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CCF54832.1 - 1.6e-07 31.6 9.1 0.79 10.1 0.0 8.6 9 0 0 9 9 9 3 Late embryogenesis abundant protein zf-XS PF03470.9 CCF54833.1 - 0.066 13.2 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 XS zinc finger domain RabGAP-TBC PF00566.13 CCF54834.1 - 4.3e-50 170.1 0.1 7.6e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CCF54834.1 - 1.2e-06 27.9 0.0 2.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Meth_synt_2 PF01717.13 CCF54835.1 - 2.8e-146 486.6 0.0 1e-136 455.1 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCF54835.1 - 5.5e-124 413.4 0.1 1.9e-111 372.2 0.1 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 CCF54835.1 - 0.012 14.5 0.1 0.38 9.6 0.0 2.8 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) SHOCT PF09851.4 CCF54835.1 - 0.026 13.9 1.0 0.061 12.8 0.7 1.7 1 0 0 1 1 1 0 Short C-terminal domain DUF726 PF05277.7 CCF54836.1 - 8.6e-54 182.7 0.5 1.6e-53 181.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CCF54836.1 - 5e-06 26.5 0.1 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCF54836.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1481 PF07356.7 CCF54837.1 - 0.21 10.9 6.5 0.39 10.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) DivIC PF04977.10 CCF54837.1 - 0.96 8.9 13.4 0.93 9.0 3.2 2.8 2 1 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CCF54837.1 - 6.6 6.7 10.1 2.5 8.1 2.3 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Chorion_2 PF03964.10 CCF54837.1 - 7.8 7.1 14.9 0.029 14.8 2.9 2.6 3 1 0 3 3 3 0 Chorion family 2 GTP_EFTU PF00009.22 CCF54838.1 - 4.7e-56 189.2 0.0 6.8e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCF54838.1 - 2.3e-36 123.9 0.1 5.3e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCF54838.1 - 9.9e-16 57.6 1.5 9.9e-16 57.6 1.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCF54838.1 - 0.00048 19.7 0.3 0.0013 18.2 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCF54838.1 - 0.0017 18.2 0.3 0.0053 16.6 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TAFII55_N PF04658.8 CCF54839.1 - 5e-52 175.6 0.4 1.2e-51 174.4 0.0 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region Ribosomal_L32e PF01655.13 CCF54840.1 - 2.7e-48 162.5 2.5 3.2e-48 162.3 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L13 PF00572.13 CCF54841.1 - 4.6e-27 94.5 0.2 8.1e-27 93.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 ubiquitin PF00240.18 CCF54843.1 - 9.7e-21 72.9 0.2 1.6e-20 72.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCF54843.1 - 1.1e-10 41.0 0.4 1.6e-10 40.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCF54843.1 - 9e-07 29.0 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA PF00627.26 CCF54843.1 - 2e-05 24.2 0.0 8.2e-05 22.3 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.1 CCF54843.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCF54843.1 - 0.038 14.2 0.2 0.1 12.8 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain Mod_r PF07200.8 CCF54845.1 - 0.0071 16.2 25.9 0.0071 16.2 18.0 11.0 1 1 10 12 12 12 2 Modifier of rudimentary (Mod(r)) protein Zn_clus PF00172.13 CCF54846.1 - 0.0013 18.6 11.4 0.0022 17.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FRG1 PF06229.7 CCF54847.1 - 5.7e-19 68.3 5.3 1.4e-17 63.8 3.7 3.2 1 1 0 1 1 1 1 FRG1-like family Fascin PF06268.8 CCF54847.1 - 0.00036 20.6 0.3 0.18 11.8 0.0 2.4 1 1 1 2 2 2 2 Fascin domain RabGGT_insert PF07711.6 CCF54847.1 - 0.1 12.4 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Rab geranylgeranyl transferase alpha-subunit, insert domain DUF4504 PF14953.1 CCF54848.1 - 1.3e-13 50.8 0.0 3.9e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Transposase_mut PF00872.13 CCF54848.1 - 0.018 13.5 0.1 0.034 12.6 0.1 1.4 1 0 0 1 1 1 0 Transposase, Mutator family Mito_carr PF00153.22 CCF54849.1 - 1.9e-65 216.5 4.5 4.3e-23 80.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SUZ PF12752.2 CCF54850.1 - 2.1e-12 47.3 3.3 2.1e-12 47.3 2.3 2.4 3 0 0 3 3 3 1 SUZ domain FNIP_N PF14636.1 CCF54850.1 - 0.84 10.1 5.3 1.4 9.3 3.6 1.6 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus PBP1_TM PF14812.1 CCF54850.1 - 2.6 8.4 8.8 0.32 11.3 2.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NTP_transf_2 PF01909.18 CCF54851.1 - 7.3e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCF54851.1 - 0.0037 17.1 0.0 0.045 13.7 0.0 2.6 1 1 0 1 1 1 1 Cid1 family poly A polymerase Cupin_8 PF13621.1 CCF54852.1 - 0.1 12.0 0.5 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 Cupin-like domain Rep_fac_C PF08542.6 CCF54853.1 - 6.6e-22 77.2 0.3 1.7e-20 72.7 0.0 2.5 3 0 0 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCF54853.1 - 2.8e-11 43.3 0.0 4.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CCF54853.1 - 2.2e-05 23.3 0.0 0.0027 16.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 CCF54853.1 - 6.8e-05 23.0 0.1 0.00021 21.4 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCF54853.1 - 8.6e-05 22.6 0.0 0.00028 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CCF54853.1 - 0.0024 17.9 0.1 0.11 12.5 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 CCF54853.1 - 0.0026 16.8 0.0 0.45 9.5 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCF54853.1 - 0.0072 16.3 0.2 0.63 9.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CCF54853.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain SNF2_N PF00176.18 CCF54853.1 - 0.014 14.1 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DNA_pol3_delta PF06144.8 CCF54853.1 - 0.015 14.7 0.1 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 CCF54853.1 - 0.046 13.2 0.1 0.41 10.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCF54853.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCF54853.1 - 0.091 13.0 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CCF54853.1 - 0.12 12.0 0.0 0.56 9.8 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase DEAD PF00270.24 CCF54855.1 - 1e-34 119.4 0.0 3.7e-34 117.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54855.1 - 1.9e-21 75.6 0.0 6.6e-21 73.9 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCF54855.1 - 1.6e-07 31.3 0.0 7.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCF54855.1 - 0.0011 18.6 0.3 0.0045 16.6 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCF54855.1 - 0.068 13.3 4.5 0.26 11.4 0.6 2.9 2 1 0 2 2 2 0 AAA domain Tfb4 PF03850.9 CCF54856.1 - 4.3e-71 239.4 1.9 9.7e-70 234.9 1.3 2.2 1 1 0 1 1 1 1 Transcription factor Tfb4 TrbI PF03743.9 CCF54856.1 - 3.6 7.0 8.2 0.13 11.7 0.5 2.2 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein IGR PF09597.5 CCF54857.1 - 2.4e-12 46.5 0.3 5e-12 45.5 0.2 1.6 1 1 0 1 1 1 1 IGR protein motif 60KD_IMP PF02096.15 CCF54858.1 - 2.5e-16 59.9 0.0 1.2e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein Phage_Coat_B PF05356.6 CCF54858.1 - 9.7 5.9 7.1 14 5.4 2.1 3.0 3 0 0 3 3 3 0 Phage Coat protein B ResIII PF04851.10 CCF54859.1 - 4.3e-18 65.7 0.0 2e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCF54859.1 - 6.7e-18 64.7 0.0 2.3e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54859.1 - 1.4e-17 63.3 0.0 3.3e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCF54859.1 - 0.0046 15.7 0.0 0.0098 14.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain EF-hand_1 PF00036.27 CCF54860.1 - 4.5e-26 88.1 15.2 2.2e-09 35.9 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCF54860.1 - 8.7e-25 84.3 10.5 1.2e-08 34.0 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CCF54860.1 - 1.1e-24 86.2 11.9 2.8e-12 46.5 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCF54860.1 - 5e-17 61.2 14.2 1e-10 41.0 1.3 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CCF54860.1 - 1.7e-14 52.3 12.8 5.6e-06 25.4 0.1 4.3 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 CCF54860.1 - 2.7e-10 40.0 0.6 0.00038 20.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCF54860.1 - 4.5e-08 32.7 3.5 0.0006 19.5 0.1 2.5 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CCF54860.1 - 0.0079 15.7 0.1 0.18 11.3 0.0 2.7 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.3 CCF54860.1 - 0.045 13.1 0.9 2.8 7.2 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3164) Toprim_2 PF13155.1 CCF54860.1 - 0.047 14.0 3.1 4 7.8 0.1 2.4 1 1 1 2 2 2 0 Toprim-like DUF2313 PF10076.4 CCF54860.1 - 0.057 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) DUF1636 PF07845.6 CCF54860.1 - 0.086 13.0 0.0 2.2 8.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1636) SPARC_Ca_bdg PF10591.4 CCF54860.1 - 0.21 11.6 4.4 3 7.9 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region G-patch PF01585.18 CCF54861.1 - 3.6e-12 45.8 0.6 9.3e-12 44.5 0.4 1.8 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 CCF54861.1 - 9.5e-09 34.8 0.0 2.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 CCF54861.1 - 3.7e-05 23.4 0.6 0.00023 20.9 0.4 2.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3317 PF11779.3 CCF54862.1 - 3.9e-15 55.0 4.5 5.6e-15 54.5 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Rubella_E2 PF05749.6 CCF54862.1 - 3 7.0 7.4 0.14 11.4 0.2 1.9 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Apc3 PF12895.2 CCF54863.1 - 0.0011 19.0 0.7 0.0054 16.8 0.5 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CCF54863.1 - 0.018 14.9 0.2 0.018 14.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCF54863.1 - 0.046 14.1 4.8 0.5 10.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCF54863.1 - 0.057 13.2 0.1 0.35 10.7 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCF54863.1 - 0.27 10.8 3.6 0.58 9.8 0.9 2.5 2 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 CCF54863.1 - 0.34 10.5 4.1 0.12 11.9 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCF54863.1 - 0.72 9.8 8.2 0.52 10.2 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCF54863.1 - 4.2 7.7 11.0 1.1 9.6 1.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.18 CCF54864.1 - 2.1e-14 53.3 0.7 3.2e-14 52.7 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCF54864.1 - 2.7e-07 30.6 0.2 3.7e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.14 CCF54864.1 - 0.0062 16.9 0.7 0.0089 16.4 0.5 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glypican PF01153.14 CCF54864.1 - 0.027 13.0 0.1 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Glypican Ras PF00071.17 CCF54865.1 - 5.9e-57 191.5 0.2 7.7e-57 191.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCF54865.1 - 1.2e-18 67.6 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCF54865.1 - 1.4e-15 56.9 0.0 4.1e-15 55.4 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCF54865.1 - 3.7e-07 29.5 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCF54865.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCF54865.1 - 0.0016 18.3 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCF54865.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain HSP70 PF00012.15 CCF54866.1 - 3.8e-59 200.1 2.4 2.3e-55 187.6 0.0 4.0 3 1 0 3 3 3 2 Hsp70 protein GAGA_bind PF06217.7 CCF54866.1 - 0.76 9.6 12.5 1.7 8.5 8.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Metallophos PF00149.23 CCF54867.1 - 1.2e-40 139.0 0.7 1.8e-40 138.4 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_LMP2 PF07415.6 CCF54868.1 - 0.023 13.3 8.1 0.027 13.0 5.6 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein UCH PF00443.24 CCF54871.1 - 4.3e-48 163.7 0.0 9.7e-48 162.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCF54871.1 - 9.6e-20 71.1 0.1 1.7e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCF54871.1 - 2.5e-13 49.9 3.1 2.5e-13 49.9 2.1 2.8 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.7 CCF54871.1 - 3.3 7.1 6.3 14 5.0 1.4 2.9 2 0 0 2 2 2 0 TFIIB zinc-binding zf-met PF12874.2 CCF54871.1 - 5.2 7.4 7.3 0.67 10.2 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Abhydrolase_3 PF07859.8 CCF54872.1 - 7e-18 64.9 0.0 5.3e-16 58.8 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCF54872.1 - 3e-11 42.6 0.0 1.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 CCF54872.1 - 0.042 14.0 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.3 CCF54872.1 - 0.24 10.7 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Methyltransf_15 PF09445.5 CCF54873.1 - 1.8e-33 115.3 0.0 8.3e-26 90.4 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CCF54873.1 - 3.6e-08 33.4 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CCF54873.1 - 1.1e-05 25.0 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CCF54873.1 - 4.5e-05 23.9 0.0 8.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCF54873.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 CCF54873.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 CCF54873.1 - 0.0026 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Cons_hypoth95 PF03602.10 CCF54873.1 - 0.022 14.1 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.6 CCF54873.1 - 0.022 13.4 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase ADH_zinc_N PF00107.21 CCF54873.1 - 0.07 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PrmA PF06325.8 CCF54873.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RVT_2 PF07727.9 CCF54874.1 - 3.5e-48 163.7 0.3 3.5e-36 124.4 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 CCF54874.1 - 7.3e-06 25.5 0.1 2.4e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Mo25 PF08569.6 CCF54875.1 - 1.3e-127 425.4 2.2 1.9e-127 424.9 1.5 1.1 1 0 0 1 1 1 1 Mo25-like DUF2183 PF09949.4 CCF54875.1 - 0.027 14.4 0.0 0.098 12.6 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) HEAT_2 PF13646.1 CCF54875.1 - 0.029 14.6 0.0 0.63 10.3 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats RepA_N PF06970.6 CCF54875.1 - 0.29 10.9 2.0 0.46 10.3 0.2 2.2 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Period_C PF12114.3 CCF54875.1 - 7.5 6.1 9.3 14 5.2 6.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3518 PF12031.3 CCF54876.1 - 2.2e-06 26.6 5.5 1e-05 24.4 0.0 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3518) Peptidase_M41 PF01434.13 CCF54877.1 - 1.7e-71 240.0 0.2 2.7e-71 239.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCF54877.1 - 9.7e-43 145.5 0.0 2.2e-42 144.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCF54877.1 - 1.4e-13 50.9 0.1 3.3e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 CCF54877.1 - 0.00029 20.9 0.0 0.18 11.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCF54877.1 - 0.001 19.9 0.0 0.0051 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CCF54877.1 - 0.0014 17.4 0.1 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CCF54877.1 - 0.004 16.8 0.7 0.014 15.0 0.5 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCF54877.1 - 0.0078 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCF54877.1 - 0.0082 15.8 0.1 0.042 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF54877.1 - 0.018 15.0 0.2 0.14 12.0 0.1 2.2 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 CCF54877.1 - 0.021 13.9 0.1 0.063 12.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 CCF54877.1 - 0.025 14.5 0.6 0.12 12.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CCF54877.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 CCF54877.1 - 0.053 12.9 0.7 0.16 11.3 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 CCF54877.1 - 0.12 12.2 0.1 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCF54877.1 - 0.71 10.1 0.0 0.71 10.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Drf_GBD PF06371.8 CCF54878.1 - 1.1e-08 34.7 0.0 5e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Rcd1 PF04078.8 CCF54878.1 - 0.24 10.2 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Kinesin PF00225.18 CCF54879.1 - 5.8e-112 373.6 0.1 5.8e-112 373.6 0.1 2.3 2 1 1 3 3 3 1 Kinesin motor domain DUF3450 PF11932.3 CCF54879.1 - 0.0027 17.0 1.3 0.0027 17.0 0.9 6.0 3 1 3 6 6 6 1 Protein of unknown function (DUF3450) Secretin_N PF03958.12 CCF54879.1 - 0.099 12.8 0.0 0.099 12.8 0.0 3.8 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain GATA PF00320.22 CCF54880.1 - 5.6e-13 48.0 5.8 1.2e-12 46.9 4.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 CCF54880.1 - 0.0033 17.4 2.7 0.055 13.5 0.0 2.9 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.6 CCF54880.1 - 0.11 12.5 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold GCD14 PF08704.5 CCF54881.1 - 1.5e-82 276.8 7.0 1.9e-47 161.8 3.0 3.3 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CCF54881.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54881.1 - 0.021 15.4 0.0 4.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain Velvet PF11754.3 CCF54883.1 - 1.1e-48 165.5 0.5 1.5e-33 116.1 0.0 2.4 2 0 0 2 2 2 2 Velvet factor LSM PF01423.17 CCF54885.1 - 3.6e-17 61.6 0.3 4.3e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCF54885.1 - 7.6e-06 25.7 0.3 1.3e-05 25.0 0.1 1.5 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 CCF54885.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain DHH PF01368.15 CCF54887.1 - 1.6e-09 37.5 0.0 3.8e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 CCF54887.1 - 8.7e-06 25.9 0.0 2.4e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 DHHA2 domain WD40 PF00400.27 CCF54888.1 - 3.9e-06 26.5 0.6 3.2e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 WD domain, G-beta repeat UCR_hinge PF02320.11 CCF54889.1 - 1.5e-20 72.8 3.8 2.4e-20 72.2 2.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 CCF54889.1 - 0.025 14.1 3.9 0.025 14.1 2.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 CCF54889.1 - 0.033 13.4 4.3 0.038 13.2 3.0 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.14 CCF54889.1 - 0.037 14.4 5.0 0.058 13.7 3.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein ATG22 PF11700.3 CCF54889.1 - 0.04 12.3 0.1 0.044 12.2 0.1 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4611 PF15387.1 CCF54889.1 - 0.09 12.9 4.9 0.12 12.4 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) YqfQ PF14181.1 CCF54889.1 - 0.097 12.7 0.6 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 CCF54889.1 - 0.1 10.6 0.9 0.087 10.8 0.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 CCF54889.1 - 0.18 12.0 11.9 0.28 11.4 8.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 CCF54889.1 - 0.35 10.6 3.2 0.42 10.3 2.2 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 CCF54889.1 - 0.41 10.1 11.1 0.6 9.6 7.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 CCF54889.1 - 0.42 8.7 6.0 0.45 8.6 4.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TLP-20 PF06088.6 CCF54889.1 - 0.48 10.0 2.1 0.56 9.8 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.7 CCF54889.1 - 2.4 7.1 10.0 3 6.9 6.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Prp19_bind PF06991.6 CCF54889.1 - 2.6 7.2 9.3 2.8 7.1 6.4 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Daxx PF03344.10 CCF54889.1 - 4 5.8 11.8 4.4 5.6 8.2 1.1 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 CCF54889.1 - 4.1 7.1 6.2 5.3 6.7 4.3 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop14 PF04147.7 CCF54889.1 - 5.5 4.7 10.6 6.3 4.5 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CCF54889.1 - 5.6 6.1 9.1 6.4 5.9 6.3 1.0 1 0 0 1 1 1 0 SDA1 Radial_spoke PF04712.7 CCF54889.1 - 6.9 5.3 11.5 8.5 5.0 8.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein alpha-hel2 PF14456.1 CCF54889.1 - 7.8 5.1 7.5 9.2 4.9 5.2 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF3384 PF11864.3 CCF54890.1 - 1e-102 344.0 0.0 2.8e-97 326.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 CCF54890.1 - 5e-52 176.0 0.0 8.6e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 CCF54890.1 - 2.8e-28 99.0 10.1 9.1e-26 90.7 6.1 3.3 3 1 0 3 3 3 2 Tuberin FMN_dh PF01070.13 CCF54891.1 - 2.9e-122 407.9 0.7 3.4e-122 407.7 0.5 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCF54891.1 - 2e-22 78.7 0.0 5.5e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 CCF54891.1 - 7.3e-05 21.8 0.2 0.00012 21.0 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CCF54891.1 - 9e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCF54891.1 - 0.00042 19.5 0.6 0.00069 18.8 0.4 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 CCF54891.1 - 0.042 12.9 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCF54891.1 - 0.044 13.0 0.1 0.11 11.7 0.0 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 CCF54891.1 - 0.077 11.9 0.1 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Arm PF00514.18 CCF54891.1 - 0.094 12.5 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Aminotran_1_2 PF00155.16 CCF54892.1 - 1.4e-49 168.9 0.0 1.7e-46 158.8 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCF54892.1 - 0.0045 16.1 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 CCF54892.1 - 0.048 12.2 0.0 0.088 11.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain SAMP PF05924.6 CCF54892.1 - 0.12 11.5 1.4 0.16 11.1 0.1 1.9 2 0 0 2 2 2 0 SAMP Motif Ribosomal_L24e PF01246.15 CCF54893.1 - 2.5e-31 107.3 0.6 2.5e-31 107.3 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4551 PF15087.1 CCF54893.1 - 0.27 9.5 1.2 0.45 8.8 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) HLH PF00010.21 CCF54894.1 - 1.8e-09 37.1 0.2 3.8e-09 36.1 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMEM51 PF15345.1 CCF54894.1 - 0.014 15.1 6.1 0.067 12.8 2.7 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 Med15 PF09606.5 CCF54894.1 - 0.016 13.4 30.5 0.024 12.8 21.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CCF54894.1 - 0.026 13.2 30.8 0.065 11.9 21.4 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.4 CCF54894.1 - 0.038 12.2 11.3 0.066 11.4 7.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TMEM247 PF15444.1 CCF54894.1 - 0.14 11.9 4.8 0.25 11.1 3.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Serinc PF03348.10 CCF54894.1 - 0.27 9.9 6.1 0.37 9.4 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S49_N PF08496.5 CCF54894.1 - 8.2 6.2 9.9 4.8 6.9 4.5 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF619 PF04768.8 CCF54895.1 - 7e-47 159.0 0.1 1.4e-46 158.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCF54895.1 - 1.5e-26 93.0 0.0 4.1e-26 91.6 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCF54895.1 - 3.1e-20 72.7 0.0 6.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 CCF54895.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.8 CCF54895.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Pam16 zf-C2H2 PF00096.21 CCF54896.1 - 3.4e-10 39.6 15.0 1.2e-05 25.3 2.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCF54896.1 - 1.9e-07 30.9 13.9 0.001 19.2 1.6 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCF54896.1 - 6.6e-06 26.1 13.1 3e-05 24.0 1.8 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CCF54896.1 - 0.58 10.4 2.9 9.4 6.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SIN1 PF05422.7 CCF54897.1 - 1e-30 106.7 0.0 3.6e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 CCF54897.1 - 0.03 14.8 0.1 0.27 11.7 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Myb_DNA-bind_6 PF13921.1 CCF54898.1 - 0.00099 19.1 0.1 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain RasGAP PF00616.14 CCF54899.1 - 6.4e-56 189.1 0.5 2.6e-55 187.1 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 CCF54899.1 - 2.5e-41 140.6 0.4 2.5e-41 140.6 0.3 2.0 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 CCF54899.1 - 0.013 15.8 5.2 0.26 11.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) KxDL PF10241.4 CCF54899.1 - 0.48 10.3 5.6 2.5 8.0 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein RVT_2 PF07727.9 CCF54900.1 - 8.5e-52 175.5 1.0 3.2e-44 150.7 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCF54900.1 - 0.028 14.5 0.0 0.074 13.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Spc97_Spc98 PF04130.8 CCF54902.1 - 1.4e-117 393.3 0.0 1.7e-117 392.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family AMP-binding PF00501.23 CCF54904.1 - 3.7e-10 38.7 0.1 3.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Kin17_mid PF10357.4 CCF54905.1 - 1.4e-48 163.6 0.9 1.4e-48 163.6 0.6 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CCF54905.1 - 4.3e-06 26.7 2.4 8.7e-06 25.7 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCF54905.1 - 1.8e-05 24.7 1.5 3.8e-05 23.7 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCF54905.1 - 0.0025 17.8 1.6 0.0071 16.4 0.0 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CCF54905.1 - 0.015 15.0 2.9 0.015 15.0 0.3 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CCF54905.1 - 0.068 13.5 1.4 0.18 12.1 1.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger SRC-1 PF08832.5 CCF54905.1 - 3.8 8.3 14.1 0.074 13.8 1.9 3.2 2 1 0 2 2 2 0 Steroid receptor coactivator DUF775 PF05603.7 CCF54905.1 - 4.2 6.8 6.5 10 5.6 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF775) Pkinase PF00069.20 CCF54906.1 - 1.4e-51 175.1 0.0 8.3e-48 162.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCF54906.1 - 4.7e-20 71.7 0.0 4.3e-16 58.7 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 CCF54906.1 - 0.00048 19.9 0.2 0.0051 16.5 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CCF54906.1 - 0.0093 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCF54906.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RGS PF00615.14 CCF54907.1 - 1.6e-12 47.5 0.1 6.6e-07 29.4 0.0 2.4 2 1 0 2 2 2 2 Regulator of G protein signaling domain FA_desaturase PF00487.19 CCF54908.1 - 3.2e-16 59.5 25.2 5.7e-16 58.7 17.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCF54908.1 - 2.2e-14 53.0 0.0 4.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lactamase_B PF00753.22 CCF54908.1 - 0.008 15.8 0.2 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF1673 PF07895.6 CCF54908.1 - 0.11 12.0 0.1 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DHH PF01368.15 CCF54909.1 - 2e-08 33.9 0.0 1.2e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 CCF54909.1 - 0.037 14.2 0.1 0.067 13.3 0.0 1.6 1 1 0 1 1 1 0 DHHA2 domain Ribonuc_2-5A PF06479.7 CCF54909.1 - 0.042 13.6 2.3 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Ribonuclease 2-5A UBA_4 PF14555.1 CCF54909.1 - 0.12 11.9 0.2 0.34 10.4 0.1 1.8 2 0 0 2 2 2 0 UBA-like domain SNARE_assoc PF09335.6 CCF54910.1 - 1.1e-30 106.3 5.5 3.6e-30 104.6 3.7 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein SHMT PF00464.14 CCF54912.1 - 1.2e-175 583.6 0.0 1.4e-175 583.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCF54912.1 - 0.00031 19.9 0.0 0.00048 19.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase IPPT PF01715.12 CCF54912.1 - 0.056 12.4 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 IPP transferase Macro PF01661.16 CCF54912.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Macro domain DCP2 PF05026.8 CCF54913.1 - 5.7e-32 109.4 0.0 8.9e-32 108.8 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain DUF427 PF04248.7 CCF54913.1 - 8.9e-27 92.5 0.4 4.7e-26 90.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF427) NUDIX PF00293.23 CCF54913.1 - 3.5e-15 55.8 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Cys_Met_Meta_PP PF01053.15 CCF54915.1 - 5.7e-139 462.6 0.0 1.7e-138 461.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCF54915.1 - 0.0065 15.5 0.0 0.014 14.4 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family ADK PF00406.17 CCF54916.1 - 9.4e-07 28.8 0.0 0.00042 20.2 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CCF54916.1 - 0.0004 21.2 0.1 0.0012 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain V-SNARE PF05008.10 CCF54916.1 - 0.018 15.2 0.1 0.23 11.6 0.0 2.8 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus AAA_33 PF13671.1 CCF54916.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Exo70 PF03081.10 CCF54916.1 - 0.024 13.4 0.3 1.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Exo70 exocyst complex subunit AAA_16 PF13191.1 CCF54916.1 - 0.027 14.4 0.3 2.2 8.2 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 CCF54916.1 - 0.03 14.6 0.1 0.083 13.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 CCF54916.1 - 0.038 14.2 0.1 0.15 12.4 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CCF54916.1 - 0.096 12.8 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 CCF54916.1 - 0.45 9.9 5.8 0.55 9.6 0.0 3.1 2 1 0 3 3 3 0 Guanylate kinase SIR2 PF02146.12 CCF54917.1 - 2.1e-55 187.2 0.0 3.4e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CCF54917.1 - 6.6e-09 35.4 0.8 8.6e-06 25.3 0.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF592) CutC PF03932.9 CCF54917.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 CutC family TPP_enzyme_M PF00205.17 CCF54917.1 - 0.1 12.3 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain SURF2 PF05477.6 CCF54917.1 - 1 8.4 5.6 0.17 10.9 0.2 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) NGP1NT PF08153.7 CCF54918.1 - 1.7e-42 144.4 0.0 4.3e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCF54918.1 - 5.9e-18 64.9 0.0 1e-14 54.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCF54918.1 - 1.6e-05 24.2 0.2 6.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CCF54918.1 - 0.00017 20.8 0.1 0.058 12.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CCF54918.1 - 0.0016 17.6 0.1 0.0052 15.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCF54918.1 - 0.027 13.8 3.5 0.44 9.9 0.0 3.3 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCF54918.1 - 0.067 13.0 7.5 0.41 10.4 0.0 4.1 4 1 1 5 5 5 0 Dynamin family zf-CCCH PF00642.19 CCF54919.1 - 3.9e-09 35.9 11.0 2.3e-07 30.3 3.1 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 CCF54919.1 - 1.6e-07 31.0 13.4 5.4e-07 29.3 7.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCF54919.1 - 1.7e-06 27.5 11.7 1.7e-06 27.5 8.1 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCF54919.1 - 4.9e-06 26.4 10.8 1.5e-05 24.8 7.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCF54919.1 - 3.2e-05 23.5 10.4 9.5e-05 22.0 7.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCF54919.1 - 4.5e-05 23.0 9.2 0.00011 21.8 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCF54919.1 - 0.0062 16.3 8.8 0.018 14.9 6.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING LRV_FeS PF05484.6 CCF54919.1 - 0.039 13.5 1.8 0.1 12.1 0.5 2.1 2 0 0 2 2 2 0 LRV protein FeS4 cluster PAM2 PF07145.10 CCF54919.1 - 0.084 12.4 1.7 8.6 6.1 0.1 3.1 2 1 1 3 3 3 0 Ataxin-2 C-terminal region zf-RING_4 PF14570.1 CCF54919.1 - 0.27 10.8 8.4 0.7 9.5 5.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 CCF54919.1 - 0.32 10.8 6.5 1.7 8.5 4.6 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCF54919.1 - 0.52 10.4 11.9 3.4 7.8 8.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 CCF54919.1 - 1.1 9.3 9.8 3.4 7.7 6.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RPE65 PF03055.10 CCF54920.1 - 1.2e-137 459.4 0.0 1.4e-137 459.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 CCF54920.1 - 0.13 11.8 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor SNF2_N PF00176.18 CCF54921.1 - 2.2e-48 164.6 0.0 2.9e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCF54921.1 - 4.4e-17 61.7 0.0 4.4e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.1 CCF54921.1 - 1.7e-14 53.4 1.0 4.4e-14 52.1 0.7 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 CCF54921.1 - 0.0038 17.0 0.0 0.056 13.2 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Rifin_STEVOR PF02009.11 CCF54923.1 - 0.84 9.2 3.1 0.81 9.2 2.2 1.3 1 0 0 1 1 1 0 Rifin/stevor family Macoilin PF09726.4 CCF54923.1 - 6.6 4.8 15.0 7.8 4.6 10.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Elf1 PF05129.8 CCF54924.1 - 8.7e-29 99.0 0.5 9.8e-29 98.8 0.4 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.1 CCF54924.1 - 0.36 10.7 4.0 1.3 9.0 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CCF54924.1 - 0.73 9.8 3.7 3.2 7.7 2.7 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Ank_4 PF13637.1 CCF54925.1 - 8.4e-15 54.8 0.2 1e-06 29.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCF54925.1 - 2.6e-13 50.1 0.2 7.9e-11 42.1 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCF54925.1 - 1.3e-10 41.1 0.1 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCF54925.1 - 1.3e-08 34.2 0.1 2.4e-06 27.0 0.2 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CCF54925.1 - 2.9e-06 26.9 0.2 0.00011 22.1 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat BMP2K_C PF15282.1 CCF54925.1 - 0.013 15.6 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus DUF2312 PF10073.4 CCF54925.1 - 0.073 12.4 0.4 0.25 10.7 0.1 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) HSP70 PF00012.15 CCF54927.1 - 1.4e-261 868.7 10.9 1.6e-261 868.5 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCF54927.1 - 2.4e-19 69.0 1.1 1.3e-18 66.6 0.3 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CCF54927.1 - 0.0037 16.4 7.0 0.035 13.1 0.2 3.4 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Spc7 PF08317.6 CCF54927.1 - 0.055 12.1 2.4 0.11 11.1 1.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Latarcin PF10279.4 CCF54927.1 - 2.6 8.3 6.5 41 4.4 2.7 2.8 2 0 0 2 2 2 0 Latarcin precursor Seryl_tRNA_N PF02403.17 CCF54927.1 - 3 7.9 15.6 3.4 7.7 3.2 4.0 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ScpA_ScpB PF02616.9 CCF54927.1 - 3 7.3 6.4 0.5 9.8 1.2 2.0 2 0 0 2 2 2 0 ScpA/B protein DUF4404 PF14357.1 CCF54927.1 - 5.8 7.4 7.5 5.6 7.4 1.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) zf-U1 PF06220.7 CCF54928.1 - 6.2e-08 32.0 1.2 1.1e-07 31.2 0.9 1.4 1 0 0 1 1 1 1 U1 zinc finger IU_nuc_hydro PF01156.14 CCF54929.1 - 1.3e-116 389.1 0.0 1.8e-116 388.7 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase S1-P1_nuclease PF02265.11 CCF54930.1 - 5.8e-47 160.4 0.0 9.5e-45 153.1 0.0 2.4 1 1 0 1 1 1 1 S1/P1 Nuclease LRR_6 PF13516.1 CCF54931.1 - 4.8e-05 23.0 1.5 1 9.6 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CCF54931.1 - 0.001 18.6 0.0 1.8 8.2 0.0 4.4 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCF54931.1 - 0.0052 16.6 0.6 38 4.8 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich Repeat ATP-synt_G PF04718.10 CCF54932.1 - 5.4e-20 71.9 0.2 1.2e-19 70.8 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF1911 PF08929.5 CCF54932.1 - 0.058 14.0 0.1 0.094 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) EF-hand_6 PF13405.1 CCF54933.1 - 1.8e-15 55.3 0.8 3.2e-06 26.5 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CCF54933.1 - 2.7e-14 53.0 0.1 4.1e-08 33.2 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCF54933.1 - 2.3e-12 45.2 2.1 1.1e-05 24.3 0.0 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 CCF54933.1 - 3.4e-07 29.7 0.4 0.00066 19.2 0.0 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CCF54933.1 - 7.7e-06 25.7 0.0 0.00085 19.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CCF54933.1 - 1.1e-05 24.5 3.7 0.0051 16.0 0.3 2.9 3 0 0 3 3 3 2 EF hand EFhand_Ca_insen PF08726.5 CCF54933.1 - 0.00067 19.5 0.0 0.28 11.1 0.0 2.4 2 1 0 2 2 2 2 Ca2+ insensitive EF hand UPF0154 PF03672.8 CCF54933.1 - 0.03 13.9 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) RNA_pol_Rpb4 PF03874.11 CCF54933.1 - 0.061 13.3 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb4 Big_3_2 PF12245.3 CCF54933.1 - 0.079 12.5 0.4 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF3602 PF12223.3 CCF54934.1 - 3.3e-17 62.6 28.2 5.6e-15 55.5 5.9 4.1 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) T4SS PF07996.6 CCF54934.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.4 1 1 0 1 1 1 0 Type IV secretion system proteins Mak10 PF04112.8 CCF54935.1 - 8.7e-52 174.7 0.0 1.7e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DEAD PF00270.24 CCF54936.1 - 4.5e-19 68.5 0.0 1.3e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCF54936.1 - 0.00038 20.2 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fe-S_biosyn PF01521.15 CCF54937.1 - 5.4e-17 61.7 0.0 8.2e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_C42 PF05533.7 CCF54937.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Beet yellows virus-type papain-like endopeptidase C42 AAA PF00004.24 CCF54938.1 - 5.8e-44 149.4 0.0 1.1e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCF54938.1 - 3.9e-08 33.3 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCF54938.1 - 2.2e-06 27.4 0.0 9.5e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCF54938.1 - 2.7e-06 27.4 0.1 1.8e-05 24.8 0.0 2.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CCF54938.1 - 3.1e-06 27.3 0.1 0.00029 20.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCF54938.1 - 9.6e-05 22.0 0.0 0.0003 20.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCF54938.1 - 0.00012 22.9 0.0 0.00029 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCF54938.1 - 0.00012 21.2 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCF54938.1 - 0.00037 19.9 0.0 0.00078 18.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CCF54938.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CCF54938.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCF54938.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCF54938.1 - 0.003 17.5 0.2 0.0075 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 CCF54938.1 - 0.0031 16.6 0.0 0.0064 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 CCF54938.1 - 0.0039 16.4 0.0 0.084 12.0 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein DUF2072 PF09845.4 CCF54938.1 - 0.0062 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_3 PF07726.6 CCF54938.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCF54938.1 - 0.0069 15.5 0.1 0.018 14.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCF54938.1 - 0.011 16.0 0.0 0.033 14.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain KaiC PF06745.8 CCF54938.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 CCF54938.1 - 0.022 14.1 0.1 0.089 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCF54938.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCF54938.1 - 0.023 14.1 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 CCF54938.1 - 0.031 13.2 0.0 0.06 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 CCF54938.1 - 0.039 13.6 0.0 0.57 9.8 0.0 2.4 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CCF54938.1 - 0.044 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 CCF54938.1 - 0.046 12.5 0.0 0.092 11.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCF54938.1 - 0.065 13.2 0.0 0.22 11.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 CCF54938.1 - 0.096 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Alpha-L-AF_C PF06964.7 CCF54941.1 - 1.2e-37 129.4 0.0 2e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 CCF54941.1 - 0.00012 22.0 1.7 0.00069 19.6 1.2 2.3 1 1 0 1 1 1 1 Carbohydrate binding domain Ferric_reduct PF01794.14 CCF54942.1 - 1.5e-14 54.1 16.6 1.5e-14 54.1 11.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCF54942.1 - 3.3e-13 49.8 0.0 5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCF54942.1 - 7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 CCF54943.1 - 1.9e-13 50.6 0.0 3.6e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CCF54943.1 - 5.3e-12 45.9 13.5 5.3e-12 45.9 9.4 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCF54943.1 - 1.6e-07 31.1 0.0 1.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain MFS_1 PF07690.11 CCF54944.1 - 9.7e-16 57.4 19.3 9e-09 34.4 3.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CCF54944.1 - 0.0017 17.0 7.5 0.0019 16.8 0.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter M-factor PF03855.8 CCF54944.1 - 0.16 12.0 3.8 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 M-factor RVP PF00077.15 CCF54945.1 - 0.1 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease RunxI PF08504.6 CCF54945.1 - 0.11 12.9 2.3 0.16 12.3 0.0 2.1 2 1 0 2 2 2 0 Runx inhibition domain Complex1_LYR PF05347.10 CCF54947.1 - 2.8e-09 36.6 0.9 4.6e-09 35.9 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCF54947.1 - 5.8e-09 36.0 0.9 8.9e-09 35.4 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF3902 PF13042.1 CCF54948.1 - 0.37 10.0 6.3 0.045 13.0 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) DUF805 PF05656.9 CCF54948.1 - 4 7.2 14.3 2 8.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF805) SH3_9 PF14604.1 CCF54949.1 - 5.2e-21 73.9 0.1 2.4e-11 43.0 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 CCF54949.1 - 9e-17 60.1 0.0 1.5e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 CCF54949.1 - 5.4e-13 48.9 0.0 5.4e-13 48.9 0.0 3.3 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 CCF54949.1 - 6.9e-13 48.1 4.1 1.2e-12 47.3 2.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 CCF54949.1 - 3.2e-12 45.7 0.0 2e-05 24.0 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_3 PF08239.6 CCF54949.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain LOH1CR12 PF10158.4 CCF54949.1 - 0.27 11.0 3.5 0.3 10.8 0.0 2.5 3 0 0 3 3 3 0 Tumour suppressor protein FHA PF00498.21 CCF54950.1 - 1.4e-15 57.1 0.1 4.6e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 FHA domain HIRA_B PF09453.5 CCF54950.1 - 0.12 11.9 0.2 0.39 10.3 0.1 1.8 1 0 0 1 1 1 0 HIRA B motif Fer2_3 PF13085.1 CCF54951.1 - 1.5e-32 111.6 0.0 2.8e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCF54951.1 - 3.8e-10 39.9 7.2 3.8e-10 39.9 5.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCF54951.1 - 1.2e-08 34.7 5.5 1.2e-08 34.7 3.8 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCF54951.1 - 8.5e-05 22.7 2.9 0.054 13.7 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCF54951.1 - 0.00022 21.6 3.2 0.00022 21.6 2.2 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCF54951.1 - 0.0005 19.8 8.0 0.00057 19.6 3.7 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCF54951.1 - 0.00064 20.0 4.9 0.00064 20.0 3.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CCF54951.1 - 0.0079 15.9 0.5 0.0079 15.9 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.3 CCF54951.1 - 0.24 11.8 1.3 1.1 9.6 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 CCF54951.1 - 0.7 10.4 6.7 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain CAP59_mtransfer PF11735.3 CCF54952.1 - 2.9e-75 252.6 0.2 3.8e-75 252.2 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CMAS PF02353.15 CCF54953.1 - 4.4e-66 222.7 0.1 1.8e-53 181.3 0.0 3.0 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CCF54953.1 - 1.1e-09 38.1 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCF54953.1 - 3e-09 37.4 0.0 1.8e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCF54953.1 - 3e-07 30.8 0.0 8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCF54953.1 - 9.1e-07 28.5 0.0 2.9e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCF54953.1 - 0.0021 18.4 0.0 0.0053 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 CCF54953.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 CCF54953.1 - 0.0093 15.9 0.0 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3155 PF11352.3 CCF54953.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) MTS PF05175.9 CCF54953.1 - 0.024 13.9 0.3 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.14 CCF54953.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RVT_2 PF07727.9 CCF54956.1 - 8.7e-06 24.8 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GATase_2 PF00310.16 CCF54956.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II APG17 PF04108.7 CCF54956.1 - 0.014 14.2 0.2 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 PCI PF01399.22 CCF54958.1 - 1.6e-07 31.5 0.0 6.3e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 PCI domain Nup96 PF12110.3 CCF54958.1 - 0.0089 15.1 0.1 0.021 13.9 0.1 1.5 1 0 0 1 1 1 1 Nuclear protein 96 TPR_19 PF14559.1 CCF54958.1 - 0.39 11.0 7.2 0.63 10.4 1.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCF54958.1 - 0.46 10.4 3.4 18 5.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCF54958.1 - 9.3 7.2 9.0 5.4 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1049 PF06305.6 CCF54959.1 - 0.035 13.5 0.2 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 CCF54959.1 - 0.056 11.7 0.0 0.08 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 CCF54959.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 CCF54959.1 - 3.6 6.9 4.7 10 5.5 3.3 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Tmemb_14 PF03647.8 CCF54960.1 - 5.8e-21 74.7 5.6 6.6e-21 74.5 3.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1427 PF07235.6 CCF54960.1 - 0.053 13.5 0.3 0.091 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) MtrG PF04210.8 CCF54961.1 - 0.0082 15.8 0.1 0.95 9.1 0.0 2.7 2 0 0 2 2 2 1 Tetrahydromethanopterin S-methyltransferase, subunit G NPV_P10 PF05531.7 CCF54961.1 - 0.41 10.9 10.0 17 5.7 0.0 4.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3422 PF11902.3 CCF54961.1 - 0.46 9.2 14.0 0.085 11.7 5.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) DUF4407 PF14362.1 CCF54961.1 - 0.57 9.0 36.9 0.55 9.1 5.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 CCF54961.1 - 3 7.7 6.8 32 4.4 0.3 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_2_N PF02837.13 CCF54962.1 - 5e-20 71.7 0.9 8.9e-20 70.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 CCF54962.1 - 1.1e-12 47.5 0.0 2.6e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 CCF54962.1 - 3e-06 27.6 0.0 1.1e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 adh_short_C2 PF13561.1 CCF54966.1 - 4.4e-25 88.8 0.1 5.7e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCF54966.1 - 6.4e-23 81.4 0.7 8.9e-23 81.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF54966.1 - 3.1e-10 40.0 0.3 5.3e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCF54966.1 - 0.031 14.2 0.1 0.09 12.7 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Fer2 PF00111.22 CCF54967.1 - 2.6e-11 43.0 0.5 4.1e-11 42.4 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ProRS-C_1 PF09180.6 CCF54968.1 - 1.6e-23 82.3 2.0 3.9e-23 81.1 1.4 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CCF54968.1 - 1.1e-22 80.4 0.1 5.6e-22 78.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCF54968.1 - 3e-18 65.5 0.0 9.9e-18 63.8 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CCF54968.1 - 2.3e-15 56.5 0.5 4e-15 55.7 0.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-CCHC PF00098.18 CCF54969.1 - 1.5e-51 169.9 59.0 1.8e-08 33.9 0.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCF54969.1 - 2e-09 36.9 45.6 0.079 12.6 0.4 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CCF54969.1 - 6.2e-08 32.2 42.9 0.36 10.5 0.8 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CCF54969.1 - 3.2e-05 23.3 39.7 0.01 15.2 0.4 7.1 4 2 3 7 7 7 6 Zinc knuckle SKN1 PF03935.10 CCF54971.1 - 6.1e-204 677.8 0.6 7.5e-204 677.5 0.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) THOC7 PF05615.8 CCF54972.1 - 2.3e-20 73.2 7.7 2.3e-20 73.2 5.3 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 Matrilin_ccoil PF10393.4 CCF54972.1 - 0.0059 15.9 1.0 0.017 14.4 0.1 2.2 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Mnd1 PF03962.10 CCF54972.1 - 0.018 14.6 2.0 0.018 14.6 1.4 1.6 2 0 0 2 2 2 0 Mnd1 family CENP-F_leu_zip PF10473.4 CCF54972.1 - 0.069 13.0 6.2 0.16 11.7 4.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.1 CCF54972.1 - 0.072 13.4 2.3 0.42 10.9 0.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin APG6 PF04111.7 CCF54972.1 - 2.9 6.8 5.9 5.6 5.9 3.5 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 UCH PF00443.24 CCF54974.1 - 4.5e-38 130.9 0.0 1.2e-33 116.3 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.24 CCF54974.1 - 2.8 7.7 3.1 1.4 8.6 0.3 1.9 2 0 0 2 2 2 0 PHD-finger Ribosomal_L14e PF01929.12 CCF54975.1 - 2.8e-26 91.6 0.6 3.6e-26 91.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCF54975.1 - 0.00016 21.2 0.4 0.00028 20.4 0.3 1.4 1 0 0 1 1 1 1 KOW motif Ribosomal_L44 PF00935.14 CCF54976.1 - 8.7e-35 118.5 12.6 1.3e-34 118.0 8.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DnaJ PF00226.26 CCF54977.1 - 2.5e-19 68.7 0.1 2.5e-19 68.7 0.1 2.5 2 1 0 2 2 2 1 DnaJ domain tRNA-synt_2b PF00587.20 CCF54978.1 - 6.1e-35 120.3 0.1 1.2e-34 119.3 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCF54978.1 - 1.3e-19 70.2 10.3 1.3e-19 70.2 7.1 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NuA4 PF09340.5 CCF54978.1 - 0.0051 16.4 0.2 0.017 14.7 0.1 1.9 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 tRNA-synt_His PF13393.1 CCF54978.1 - 0.011 14.8 0.4 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Myosin_tail_1 PF01576.14 CCF54978.1 - 0.013 13.2 10.0 0.019 12.7 6.9 1.1 1 0 0 1 1 1 0 Myosin tail PEP-utilisers_N PF05524.8 CCF54978.1 - 0.076 12.8 0.6 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Wbp11 PF09429.5 CCF54978.1 - 0.088 12.8 9.0 0.085 12.8 1.6 2.7 3 0 0 3 3 3 0 WW domain binding protein 11 YPEB PF14620.1 CCF54978.1 - 0.16 10.9 5.5 0.21 10.5 2.6 1.8 2 0 0 2 2 2 0 YpeB sporulation Mod_r PF07200.8 CCF54978.1 - 0.26 11.1 8.9 0.078 12.9 4.1 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Glyco_hydro_8 PF01270.12 CCF54979.1 - 2.6e-37 128.3 0.0 3.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 RTBV_P12 PF06361.6 CCF54980.1 - 0.088 13.0 0.4 0.28 11.4 0.3 1.8 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein Ribosomal_S8 PF00410.14 CCF54981.1 - 1.5e-23 83.0 0.0 2.1e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 CCF54982.1 - 7e-58 193.7 0.0 8.6e-58 193.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 DNA_pol_A_exo1 PF01612.15 CCF54983.1 - 5.1e-17 61.8 0.0 9.5e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 CCF54983.1 - 0.0092 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 CCF54983.1 - 0.11 12.3 0.4 58 3.6 0.1 3.6 3 0 0 3 3 3 0 Helix-turn-helix DUF2989 PF11207.3 CCF54983.1 - 0.64 9.4 3.3 1.2 8.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Prefoldin_2 PF01920.15 CCF54984.1 - 4.8e-23 80.9 12.9 5.6e-23 80.7 8.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 CCF54984.1 - 0.0019 17.8 9.5 0.0024 17.4 6.6 1.1 1 0 0 1 1 1 1 IncA protein HR1 PF02185.11 CCF54984.1 - 0.009 15.7 2.7 0.01 15.5 1.3 1.6 1 1 0 1 1 1 1 Hr1 repeat Nckap1 PF09735.4 CCF54984.1 - 0.0093 13.5 0.8 0.0097 13.4 0.5 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein Rootletin PF15035.1 CCF54984.1 - 0.021 14.7 1.5 0.021 14.7 1.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.3 CCF54984.1 - 0.025 14.4 2.0 0.025 14.4 1.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding STAT_alpha PF01017.15 CCF54984.1 - 0.031 14.0 3.5 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 STAT protein, all-alpha domain Prefoldin_3 PF13758.1 CCF54984.1 - 0.032 14.0 6.1 0.041 13.6 4.2 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF1192 PF06698.6 CCF54984.1 - 0.053 13.3 1.9 0.053 13.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Atg14 PF10186.4 CCF54984.1 - 0.098 11.5 8.8 0.12 11.3 6.1 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4349 PF14257.1 CCF54984.1 - 0.11 11.7 4.7 0.044 13.0 1.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) APG6 PF04111.7 CCF54984.1 - 0.13 11.2 7.7 0.17 10.8 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_27 PF13514.1 CCF54984.1 - 0.16 9.6 7.9 0.33 8.5 5.5 1.5 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 CCF54984.1 - 0.19 12.1 8.6 0.29 11.5 1.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Osmo_CC PF08946.5 CCF54984.1 - 0.22 11.5 5.6 0.67 10.0 3.8 2.0 1 1 0 1 1 1 0 Osmosensory transporter coiled coil Occludin_ELL PF07303.8 CCF54984.1 - 0.32 11.7 7.1 1 10.1 1.1 2.1 1 1 1 2 2 2 0 Occludin homology domain TSC22 PF01166.13 CCF54984.1 - 0.35 10.8 2.8 1.3 9.0 0.5 2.3 2 1 0 2 2 2 0 TSC-22/dip/bun family TcdA_TcdB PF12919.2 CCF54984.1 - 0.37 9.2 2.6 0.43 8.9 1.8 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Macoilin PF09726.4 CCF54984.1 - 0.4 8.9 8.1 0.44 8.7 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein FadA PF09403.5 CCF54984.1 - 0.43 10.5 7.7 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Adhesion protein FadA CENP-F_leu_zip PF10473.4 CCF54984.1 - 0.52 10.1 10.1 0.71 9.7 2.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 CCF54984.1 - 0.55 9.8 11.6 0.11 12.1 3.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 CCF54984.1 - 0.62 10.1 9.4 0.85 9.6 6.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 CCF54984.1 - 0.92 8.4 12.5 0.027 13.4 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Snf7 PF03357.16 CCF54984.1 - 0.93 8.8 12.3 0.072 12.4 4.6 1.8 2 0 0 2 2 2 0 Snf7 AAA_13 PF13166.1 CCF54984.1 - 1 7.7 7.9 1.4 7.2 5.5 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 CCF54984.1 - 1.2 9.6 5.0 1.6 9.1 3.5 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 CCF54984.1 - 1.5 8.6 12.1 7.5 6.3 8.3 2.0 1 1 0 1 1 1 0 Tropomyosin like Fib_alpha PF08702.5 CCF54984.1 - 2 8.5 8.0 3.3 7.8 5.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Pinin_SDK_memA PF04696.8 CCF54984.1 - 3.3 7.2 10.9 0.87 9.1 3.6 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region TMPIT PF07851.8 CCF54984.1 - 5.7 5.9 5.6 6.7 5.6 3.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein COG2 PF06148.6 CCF54984.1 - 6.4 6.6 8.1 2 8.2 2.0 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.1 CCF54984.1 - 7.1 7.1 8.0 2.2 8.7 0.9 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 CCF54984.1 - 8.2 6.3 9.0 19 5.1 0.5 3.3 1 1 2 3 3 3 0 Basic region leucine zipper RNA_lig_T4_1 PF09511.5 CCF54985.1 - 1.6e-74 250.0 0.0 3.3e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 CCF54985.1 - 6.9e-26 90.9 0.0 1.1e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 CCF54985.1 - 3.6e-21 75.7 0.0 7.2e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 CCF54985.1 - 0.0062 17.3 0.1 0.022 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Ecl1 PF12855.2 CCF54986.1 - 2.1e-05 23.6 0.2 0.011 15.0 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor AA_kinase PF00696.23 CCF54988.1 - 3.9e-38 131.3 0.5 8.8e-33 113.8 0.0 2.2 1 1 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 CCF54988.1 - 8e-12 44.3 0.1 1.6e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 CCF54988.1 - 4.2e-10 39.0 1.5 3.1e-07 29.8 0.2 2.6 2 0 0 2 2 2 2 ACT domain Pollen_Ole_e_I PF01190.12 CCF54988.1 - 0.044 13.6 0.0 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Pollen proteins Ole e I like Luteo_Vpg PF01659.11 CCF54988.1 - 9.2 6.0 8.2 2.8 7.6 0.6 2.4 2 0 0 2 2 2 0 Luteovirus putative VPg genome linked protein WH2 PF02205.15 CCF54990.1 - 1.2e-05 24.7 0.4 3.1e-05 23.4 0.3 1.8 1 0 0 1 1 1 1 WH2 motif Cellulase PF00150.13 CCF54992.1 - 3.3e-11 42.9 11.0 1.5e-10 40.7 7.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRMT5 PF05185.11 CCF54994.1 - 3.2e-09 36.2 0.0 7.4e-08 31.7 0.0 2.2 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 CCF54994.1 - 1.9e-05 25.2 0.0 6.4e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCF54994.1 - 5.4e-05 23.2 0.0 0.2 11.6 0.0 2.9 1 1 1 2 2 2 2 Methyltransferase domain PrmA PF06325.8 CCF54994.1 - 7.7e-05 21.9 0.1 0.0002 20.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CCF54994.1 - 0.0022 17.6 0.0 0.049 13.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCF54994.1 - 0.0028 17.3 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCF54994.1 - 0.0078 15.6 0.1 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 CCF54994.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.7 CCF54994.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_9 PF08003.6 CCF54994.1 - 0.024 13.3 0.0 0.038 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DREV PF05219.7 CCF54994.1 - 0.035 12.9 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Cons_hypoth95 PF03602.10 CCF54994.1 - 0.052 12.9 0.5 0.088 12.1 0.3 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 CCF54994.1 - 0.11 12.9 0.1 2.6 8.5 0.1 2.8 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 CCF54994.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Bromodomain PF00439.20 CCF54995.1 - 6e-21 74.1 0.0 1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF1515 PF07439.6 CCF54995.1 - 3.2 7.5 5.9 10 5.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) adh_short PF00106.20 CCF54996.1 - 7e-11 42.3 0.0 1.2e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCF54996.1 - 4.2e-05 23.2 0.1 9.5e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CCF54996.1 - 0.12 12.1 0.0 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Dus PF01207.12 CCF54997.1 - 2e-67 227.2 0.0 1.6e-66 224.2 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) YTH PF04146.10 CCF54998.1 - 6.5e-47 158.6 0.0 1.8e-46 157.2 0.0 1.7 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 CCF54998.1 - 0.0036 16.9 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCF54998.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCF54998.1 - 0.19 11.7 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)