# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- TraP PF07296.11 EGE00945.1 - 0.83 8.8 3.7 0.31 10.2 1.2 1.5 1 1 1 2 2 2 0 TraP protein RR_TM4-6 PF06459.12 EGE00945.1 - 2.4 7.9 10.9 2.9 7.6 10.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3546 PF12066.8 EGE00946.1 - 1.2e-30 106.0 0.4 1.2e-30 106.0 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EGE00946.1 - 1e-11 44.4 0.1 2.4e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EGE00946.1 - 4.3e-11 43.6 1.9 1.1e-10 42.2 1.9 1.8 1 1 0 1 1 1 1 Arsenite-resistance protein 2 ADD_ATRX PF17981.1 EGE00949.1 - 0.049 13.5 0.1 12 5.8 0.1 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain NOA36 PF06524.12 EGE00949.1 - 3.7 6.8 9.5 6.1 6.1 9.5 1.3 1 0 0 1 1 1 0 NOA36 protein bZIP_1 PF00170.21 EGE00950.1 - 0.007 16.4 11.7 0.1 12.7 11.8 2.3 1 1 0 1 1 1 1 bZIP transcription factor Med9 PF07544.13 EGE00950.1 - 0.024 14.7 4.8 0.05 13.7 2.7 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.6 EGE00950.1 - 0.18 11.4 3.1 0.27 10.8 3.1 1.2 1 0 0 1 1 1 0 TMCO5 family bZIP_2 PF07716.15 EGE00950.1 - 1 9.5 12.1 0.16 12.1 4.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TEX13 PF15186.6 EGE00950.1 - 2.2 7.9 5.4 3.7 7.2 5.4 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family eIF-3_zeta PF05091.12 EGE00951.1 - 8.1e-201 668.5 0.0 9.6e-201 668.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 EGE00952.1 - 1.3e-59 201.8 0.0 3.8e-39 134.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE00952.1 - 6.4e-29 101.0 0.0 5.1e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGE00952.1 - 5.5e-08 32.5 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGE00952.1 - 0.00012 22.1 0.5 0.0052 16.7 0.2 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE00952.1 - 0.003 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EGE00952.1 - 0.004 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 EGE00952.1 - 0.015 14.3 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain PAS PF00989.25 EGE00952.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EGE00952.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold Response_reg PF00072.24 EGE00952.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Response regulator receiver domain RIO1 PF01163.22 EGE00952.1 - 0.093 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EGE00952.1 - 0.16 11.0 0.1 0.28 10.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_CoA_synt_C PF08540.10 EGE00953.1 - 8.1e-99 330.8 3.1 9.9e-99 330.5 3.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGE00953.1 - 5.1e-87 290.2 0.0 7.6e-87 289.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 3Beta_HSD PF01073.19 EGE00954.1 - 1.3e-45 155.6 0.0 1.3e-44 152.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGE00954.1 - 6.8e-16 58.5 0.3 4.8e-15 55.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGE00954.1 - 3e-10 39.7 0.0 4.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EGE00954.1 - 3.5e-10 39.8 0.0 0.00012 21.6 0.0 3.3 2 1 0 3 3 3 3 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGE00954.1 - 0.00033 19.8 0.0 0.00098 18.3 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGE00954.1 - 0.055 13.4 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding APH PF01636.23 EGE00955.1 - 2e-11 44.3 0.0 1.1e-10 41.9 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family IDO PF01231.18 EGE00956.1 - 1.5e-33 116.3 0.0 2.1e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PRORP PF16953.5 EGE00956.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-only RNase P Gln-synt_C PF00120.24 EGE00957.1 - 9.8e-48 162.9 0.0 7.2e-47 160.1 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain FGE-sulfatase PF03781.16 EGE00958.1 - 3.7e-31 108.6 0.1 5.9e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGE00958.1 - 3.1e-06 27.7 0.3 6.6e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.6 EGE00958.1 - 5.1e-06 27.1 0.0 0.00027 21.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE00958.1 - 0.0011 19.5 0.0 0.011 16.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE00958.1 - 0.002 17.9 0.0 1.8 8.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain NAS PF03059.16 EGE00958.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein SQS_PSY PF00494.19 EGE00959.1 - 0.043 13.3 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase UQ_con PF00179.26 EGE00961.1 - 1.4e-35 122.0 0.0 6.2e-25 87.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE00961.1 - 2.2e-08 33.9 0.0 0.00043 20.0 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 EGE00961.1 - 0.0016 18.7 0.3 0.96 9.8 0.1 2.9 2 2 0 2 2 2 2 RWD domain Sybindin PF04099.12 EGE00962.1 - 6.3e-46 155.9 0.0 9.7e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGE00962.1 - 1.6e-06 28.3 0.0 3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 EGE00963.1 - 1.5e-23 83.4 0.0 2.7e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EGE00963.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EGE00963.1 - 0.012 15.5 0.3 0.037 13.9 0.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 EGE00964.1 - 7.4e-19 67.1 4.8 1.4e-18 66.3 4.8 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal RhoGAP PF00620.27 EGE00965.1 - 3.7e-33 114.5 0.1 7.1e-33 113.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EGE00965.1 - 5.1e-20 71.5 28.6 2.6e-11 43.6 6.1 4.9 5 0 0 5 5 5 3 LIM domain Nudc_N PF14050.6 EGE00965.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. AMP-binding PF00501.28 EGE00966.1 - 1.4e-68 231.4 0.0 2.3e-68 230.7 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE00966.1 - 4.2e-10 40.5 0.0 7.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb4 PF03874.16 EGE00967.1 - 2.9e-22 79.3 3.0 4.1e-22 78.8 3.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EGE00967.1 - 0.0034 17.1 0.3 0.0037 16.9 0.3 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 EGE00968.1 - 3.7e-62 209.6 0.0 5.6e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EGE00968.1 - 0.048 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase zf-GRF PF06839.12 EGE00970.1 - 2.9e-11 43.3 4.0 5.4e-11 42.4 4.0 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF3818 PF12825.7 EGE00971.1 - 2.7e-129 431.1 6.7 4.8e-129 430.2 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EGE00971.1 - 7.5e-40 135.9 0.2 1.3e-39 135.1 0.2 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EGE00971.1 - 4.7e-13 49.1 0.2 8.4e-12 45.1 0.0 3.0 2 1 0 2 2 2 1 PX domain GFD1 PF17331.2 EGE00971.1 - 0.075 13.2 2.2 0.31 11.3 2.2 2.0 1 0 0 1 1 1 0 GFD1 mRNA transport factor Aldo_ket_red PF00248.21 EGE00972.1 - 3.5e-53 180.7 0.0 1.2e-52 179.0 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.6 EGE00972.1 - 0.0081 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Hydrolase_6 PF13344.6 EGE00973.1 - 9.1e-21 73.9 0.0 2.8e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE00973.1 - 3.1e-17 62.4 0.0 6.9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGE00973.1 - 0.0053 17.1 0.0 1.7 8.9 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.9 EGE00973.1 - 0.064 12.1 0.0 0.064 12.1 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain HAD_2 PF13419.6 EGE00973.1 - 0.068 13.2 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_5 PF05631.14 EGE00976.1 - 4.7e-62 209.9 3.9 6.8e-62 209.4 3.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGE00976.1 - 9.5e-20 70.8 32.0 3.7e-19 68.9 15.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE00976.1 - 9.8e-12 44.5 4.8 9.8e-12 44.5 4.8 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter UAA PF08449.11 EGE00977.1 - 1.8e-76 257.2 12.1 3.5e-76 256.3 12.1 1.4 1 1 0 1 1 1 1 UAA transporter family TMEM100 PF16311.5 EGE00977.1 - 0.095 12.3 0.4 0.24 11.0 0.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Rad17 PF03215.15 EGE00978.1 - 4.2e-26 92.0 0.0 7.5e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGE00978.1 - 0.00022 21.6 0.3 0.00055 20.4 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 EGE00978.1 - 0.0019 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGE00978.1 - 0.0037 17.7 0.1 0.1 13.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGE00978.1 - 0.0071 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.14 EGE00978.1 - 0.008 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGE00978.1 - 0.01 16.1 0.1 0.01 16.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGE00978.1 - 0.014 16.0 4.7 0.056 14.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGE00978.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EGE00978.1 - 0.035 14.4 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE00978.1 - 0.063 13.4 0.3 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGE00978.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EGE00978.1 - 0.076 12.8 1.2 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGE00978.1 - 0.093 13.2 2.5 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EGE00978.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 EGE00978.1 - 0.19 12.2 1.6 0.35 11.4 0.0 2.3 3 0 0 3 3 3 0 ABC transporter PGA2 PF07543.12 EGE00978.1 - 1.7 8.6 7.1 31 4.6 4.8 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 ELMO_CED12 PF04727.13 EGE00979.1 - 1.5e-51 175.0 0.1 2.7e-51 174.2 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EGE00979.1 - 7.6e-32 110.7 0.0 1.7e-31 109.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EGE00979.1 - 1.4e-15 57.6 0.0 3.7e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) OATP PF03137.20 EGE00981.1 - 0.18 10.0 0.1 0.21 9.9 0.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SUI1 PF01253.22 EGE00983.1 - 9.8e-24 83.7 0.1 2.1e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 R3H-assoc PF13902.6 EGE00983.1 - 0.011 16.1 0.8 0.022 15.1 0.8 1.4 1 0 0 1 1 1 0 R3H-associated N-terminal domain SRP14 PF02290.15 EGE00983.1 - 0.054 13.9 0.3 0.091 13.1 0.3 1.4 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Img2 PF05046.14 EGE00983.1 - 0.066 13.5 0.5 0.12 12.7 0.1 1.7 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) YqfD PF06898.11 EGE00984.1 - 6.4 5.5 9.8 0.31 9.8 3.3 1.9 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD Cgr1 PF03879.14 EGE00985.1 - 1.4e-34 118.7 30.9 1.7e-34 118.4 30.9 1.1 1 0 0 1 1 1 1 Cgr1 family DUF737 PF05300.11 EGE00985.1 - 0.17 12.2 19.1 0.21 11.9 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) AAA_11 PF13086.6 EGE00985.1 - 6.1 6.5 11.0 6.2 6.5 11.0 1.1 1 0 0 1 1 1 0 AAA domain CDC27 PF09507.10 EGE00985.1 - 8 5.7 23.2 9 5.6 23.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mito_carr PF00153.27 EGE00986.1 - 2.5e-65 216.4 0.5 3.9e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 EGE00987.1 - 3.3e-15 55.8 1.0 4e-15 55.5 1.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGE00987.1 - 3e-08 33.9 3.4 3.5e-07 30.5 0.3 2.0 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGE00987.1 - 2.4e-05 24.0 2.9 0.00066 19.3 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Transp_cyt_pur PF02133.15 EGE00988.1 - 5.4e-95 318.8 36.4 6.5e-95 318.5 36.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sortilin-Vps10 PF15902.5 EGE00989.1 - 6.7e-284 941.4 3.6 7.7e-152 506.2 0.7 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGE00989.1 - 2.8e-94 314.2 20.7 3.1e-48 164.3 7.6 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGE00989.1 - 4.3e-07 29.0 28.4 0.85 9.9 0.0 9.5 10 0 0 10 10 10 6 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EGE00989.1 - 0.014 15.4 0.2 2.5 8.1 0.0 3.2 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain UBM PF14377.6 EGE00990.1 - 0.11 12.0 0.3 5.2 6.7 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin binding region APH PF01636.23 EGE00993.1 - 6.6e-06 26.2 0.1 9e-06 25.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGE00993.1 - 1.7e-05 24.4 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGE00993.1 - 0.00072 19.0 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EGE00993.1 - 0.027 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE00993.1 - 0.075 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EGE00993.1 - 0.24 10.9 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFIIS_M PF07500.14 EGE00995.1 - 3.4e-30 104.8 1.7 3.4e-30 104.8 1.7 1.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGE00995.1 - 1.9e-18 66.0 4.7 3e-18 65.4 4.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGE00995.1 - 6.6e-13 48.5 0.4 1.5e-12 47.3 0.4 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 EGE00995.1 - 0.092 12.4 0.1 0.092 12.4 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-LITAF-like PF10601.9 EGE00995.1 - 0.19 12.0 1.9 0.39 11.0 1.9 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Sec10 PF07393.11 EGE00998.1 - 1.1e-233 777.8 0.0 1.3e-233 777.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 EGE00998.1 - 0.079 12.9 0.3 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 MarR family MBOAT_2 PF13813.6 EGE00999.1 - 1.3e-16 60.6 0.2 3.3e-16 59.3 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family LRR_6 PF13516.6 EGE01000.1 - 3.4e-11 42.3 1.7 0.021 14.9 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 EGE01000.1 - 8e-09 35.6 3.1 0.17 12.3 0.5 5.4 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGE01000.1 - 0.017 15.6 7.2 59 4.8 0.1 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat BPL_N PF09825.9 EGE01000.1 - 0.57 9.2 4.6 0.85 8.6 4.6 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Nop14 PF04147.12 EGE01000.1 - 1.3 7.1 26.7 1.7 6.8 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EGE01000.1 - 4.3 6.0 6.5 5.3 5.7 6.5 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EGE01000.1 - 4.4 6.5 16.1 6.8 5.9 16.1 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.14 EGE01000.1 - 5.1 7.5 6.9 8.8 6.7 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EGE01000.1 - 5.4 6.3 28.6 7.7 5.8 28.6 1.1 1 0 0 1 1 1 0 SDA1 COX17 PF05051.13 EGE01001.1 - 2.7e-21 75.7 5.8 3.4e-21 75.3 5.8 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGE01001.1 - 0.0082 16.1 2.8 0.048 13.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.15 EGE01002.1 - 2.4e-127 425.9 22.0 5e-80 269.8 5.9 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family EpsG PF14897.6 EGE01002.1 - 0.093 12.0 6.3 0.24 10.7 6.3 1.8 1 0 0 1 1 1 0 EpsG family RRM_1 PF00076.22 EGE01003.1 - 1.1e-39 134.1 0.0 1.2e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE01003.1 - 0.00047 20.2 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif NMT1 PF09084.11 EGE01006.1 - 2.6e-79 266.2 0.0 3.3e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EGE01006.1 - 1.4e-05 24.9 0.0 0.52 10.0 0.0 3.1 3 0 0 3 3 3 2 NMT1-like family Ribosomal_L37 PF08561.10 EGE01007.1 - 3.8e-44 150.1 4.0 5.1e-44 149.6 4.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 PGA2 PF07543.12 EGE01007.1 - 2.5 8.1 6.2 3.8 7.5 1.0 2.0 1 1 1 2 2 2 0 Protein trafficking PGA2 TMEM154 PF15102.6 EGE01008.1 - 0.046 13.6 3.5 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family Beta-APP PF03494.13 EGE01008.1 - 0.3 11.0 0.7 0.48 10.3 0.7 1.3 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Cpn60_TCP1 PF00118.24 EGE01009.1 - 9.4e-147 489.6 13.2 1.1e-146 489.4 13.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EGE01010.1 - 6.1e-41 139.9 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE01010.1 - 3.3e-05 23.6 0.0 7.8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGE01010.1 - 7.2e-05 23.1 0.0 0.0073 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGE01010.1 - 0.00011 22.2 0.1 0.00043 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGE01010.1 - 0.00021 21.4 0.0 0.00069 19.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGE01010.1 - 0.00031 21.2 0.1 0.0076 16.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGE01010.1 - 0.0023 17.1 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGE01010.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGE01010.1 - 0.016 15.4 0.1 0.063 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGE01010.1 - 0.048 13.2 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGE01010.1 - 0.051 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGE01010.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGE01010.1 - 0.068 12.9 0.1 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGE01010.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGE01010.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGE01010.1 - 0.12 13.0 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGE01010.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 EGE01011.1 - 6.5e-125 417.5 3.8 8.3e-125 417.1 3.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGE01011.1 - 1e-43 148.3 1.3 1.6e-43 147.8 1.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EGE01011.1 - 2.2e-06 27.1 0.2 0.00099 18.4 0.1 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGE01011.1 - 7.7e-06 25.2 1.1 0.014 14.5 2.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EGE01011.1 - 6.8e-05 22.2 0.2 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EGE01011.1 - 0.0039 16.5 0.7 0.0085 15.4 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGE01011.1 - 0.049 13.2 1.9 0.18 11.3 1.8 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGE01011.1 - 0.21 10.2 1.3 0.94 8.1 0.7 2.3 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.21 EGE01012.1 - 1.4e-109 366.2 0.6 2e-109 365.6 0.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGE01012.1 - 2.4e-57 193.9 5.2 2.4e-57 193.9 5.2 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGE01012.1 - 3.3e-05 23.6 1.4 0.00016 21.3 0.7 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PBP1_TM PF14812.6 EGE01012.1 - 0.0014 19.0 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Esterase PF00756.20 EGE01012.1 - 0.024 14.3 0.2 0.073 12.7 0.2 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EGE01012.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PI-PLC-X PF00388.19 EGE01013.1 - 3.4e-59 198.6 0.0 6.8e-59 197.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGE01013.1 - 1.8e-41 141.1 0.0 3.7e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGE01013.1 - 0.00099 19.4 0.0 0.0031 17.8 0.0 1.8 2 0 0 2 2 2 1 C2 domain HECT_2 PF09814.9 EGE01016.1 - 3.4e-110 368.4 0.0 3.8e-110 368.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Questin_oxidase PF14027.6 EGE01018.1 - 1.4e-85 287.8 0.6 1.7e-85 287.6 0.6 1.0 1 0 0 1 1 1 1 Questin oxidase-like TPR_12 PF13424.6 EGE01019.1 - 7.4e-47 157.5 16.1 9.5e-18 64.3 1.0 5.0 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGE01019.1 - 1.2e-45 152.2 13.0 5.2e-10 38.9 0.1 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGE01019.1 - 3.7e-13 48.5 9.9 0.0061 16.6 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGE01019.1 - 5.8e-12 44.8 12.2 0.0016 18.3 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGE01019.1 - 6.4e-09 35.3 17.4 3.8e-05 23.3 0.3 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE01019.1 - 1.5e-07 31.1 11.0 0.35 11.2 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE01019.1 - 5e-07 30.3 10.4 0.15 12.8 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE01019.1 - 2.9e-06 26.9 4.0 0.0042 16.5 2.1 2.5 2 1 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EGE01019.1 - 4.2e-05 24.0 5.2 9.8 7.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGE01019.1 - 0.0013 19.1 2.9 4.8 8.1 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE01019.1 - 0.0034 17.7 9.4 0.8 10.2 0.3 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE01019.1 - 0.02 14.6 6.1 13 5.6 0.1 4.2 4 0 0 4 4 4 0 TPR repeat ANAPC3 PF12895.7 EGE01019.1 - 0.039 14.2 1.0 0.039 14.2 1.0 3.1 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGE01019.1 - 0.063 13.4 10.2 1.7 8.8 0.3 3.9 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF2989 PF11207.8 EGE01019.1 - 0.32 10.7 10.1 0.12 12.1 0.7 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2989) TPR_3 PF07720.12 EGE01019.1 - 1.3 9.1 5.2 0.54 10.3 0.2 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE01019.1 - 1.5 9.6 11.3 4.1 8.3 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA PF00004.29 EGE01020.1 - 3.9e-49 166.4 0.0 6.1e-43 146.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE01020.1 - 2.5e-06 27.2 2.4 0.0016 18.2 0.0 3.2 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EGE01020.1 - 5.1e-05 23.7 0.0 0.023 15.1 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGE01020.1 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EGE01020.1 - 0.00051 19.2 0.0 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EGE01020.1 - 0.00093 19.6 0.1 0.016 15.6 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_2 PF07724.14 EGE01020.1 - 0.0027 17.8 0.0 0.0083 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGE01020.1 - 0.0035 17.6 0.1 0.048 13.9 0.0 2.9 4 1 1 5 5 2 1 AAA domain PhoH PF02562.16 EGE01020.1 - 0.006 16.0 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein TIP49 PF06068.13 EGE01020.1 - 0.0064 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EGE01020.1 - 0.0079 15.8 0.0 0.042 13.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE01020.1 - 0.0083 16.3 0.0 0.44 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGE01020.1 - 0.0084 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGE01020.1 - 0.019 15.5 0.0 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGE01020.1 - 0.023 14.1 0.1 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGE01020.1 - 0.03 13.7 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 KaiC Vps4_C PF09336.10 EGE01020.1 - 0.031 14.3 0.5 0.61 10.1 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 EGE01020.1 - 0.032 14.2 0.0 0.13 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EGE01020.1 - 0.033 14.2 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGE01020.1 - 0.043 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Kinase-PolyVal PF18762.1 EGE01020.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins AAA_28 PF13521.6 EGE01020.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain YjbR PF04237.13 EGE01021.1 - 0.015 15.9 0.0 0.22 12.1 0.0 2.2 1 1 0 2 2 2 0 YjbR zf-C2H2 PF00096.26 EGE01023.1 - 0.0028 18.0 5.9 0.0028 18.0 5.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type C1_4 PF07975.12 EGE01023.1 - 0.059 13.6 0.3 0.16 12.2 0.3 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 EGE01023.1 - 1.1 10.3 18.1 0.08 13.8 4.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Dynamin_M PF01031.20 EGE01024.1 - 2.2e-111 371.7 0.0 3.9e-111 370.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGE01024.1 - 2.2e-57 193.8 0.7 1.8e-56 190.8 0.1 2.4 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 EGE01024.1 - 7.5e-32 109.3 0.8 1.9e-31 108.1 0.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGE01024.1 - 0.00012 22.1 0.6 0.0012 18.9 0.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGE01024.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SH3_9 PF14604.6 EGE01025.1 - 6.4e-30 102.8 3.6 3.8e-14 52.3 0.4 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGE01025.1 - 1.9e-29 101.0 4.2 1.9e-14 53.0 0.4 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGE01025.1 - 6.5e-16 57.8 0.0 2.6e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EGE01025.1 - 7.3e-16 58.1 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Brix PF04427.18 EGE01026.1 - 1.4e-36 126.5 0.0 1.8e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain PX PF00787.24 EGE01028.1 - 1.5e-14 54.0 0.0 5.6e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 PX domain SAS4 PF15460.6 EGE01029.1 - 1.1e-31 108.9 4.3 1.1e-31 108.9 4.3 2.6 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 TFIIF_alpha PF05793.12 EGE01029.1 - 0.004 15.8 20.8 0.0071 15.0 20.8 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGE01029.1 - 0.015 13.5 19.4 0.025 12.8 19.4 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EGE01029.1 - 0.066 13.6 10.3 0.17 12.3 10.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 EGE01029.1 - 1 8.5 9.8 2.2 7.4 9.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.11 EGE01029.1 - 1.7 8.3 23.6 0.33 10.6 19.7 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) BT1 PF03092.16 EGE01029.1 - 1.8 6.7 2.3 3.1 5.9 2.3 1.3 1 0 0 1 1 1 0 BT1 family DNA_pol_phi PF04931.13 EGE01029.1 - 2.9 5.9 18.3 4.5 5.3 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EGE01029.1 - 3.6 6.8 12.0 7.5 5.8 12.0 1.5 1 0 0 1 1 1 0 NOA36 protein DHHW PF14286.6 EGE01029.1 - 5 6.3 4.9 10 5.3 4.9 1.4 1 0 0 1 1 1 0 DHHW protein PY_rept_46 PF09689.10 EGE01031.1 - 8.5 7.0 9.1 7 7.3 0.4 3.0 1 1 2 3 3 3 0 Plasmodium yoelii repeat (PY_rept_46) DUF3807 PF12720.7 EGE01032.1 - 4.3e-43 147.7 2.6 5.5e-43 147.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) HVSL PF09749.9 EGE01033.1 - 2.2e-84 282.7 0.1 2.9e-84 282.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Terpene_synth_C PF03936.16 EGE01034.1 - 2.9e-07 30.1 0.6 6.4e-07 29.0 0.6 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Pal1 PF08316.11 EGE01035.1 - 1e-07 32.8 0.3 1.8e-07 32.0 0.3 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Methyltransf_28 PF02636.17 EGE01036.1 - 5.4e-40 137.7 0.0 1e-39 136.8 0.0 1.4 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pathogen_betaC1 PF09593.10 EGE01036.1 - 0.16 11.9 0.3 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein PALP PF00291.25 EGE01037.1 - 3.8e-60 203.8 2.1 9.1e-60 202.5 2.1 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.9 EGE01038.1 - 2.4e-22 78.4 0.1 4.7e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.6 EGE01038.1 - 0.00025 21.2 1.7 0.58 10.5 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE01038.1 - 0.00029 21.0 0.2 3.1 8.1 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain APG6 PF04111.12 EGE01039.1 - 6e-73 244.6 0.0 9e-73 244.0 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EGE01039.1 - 7.6e-39 133.3 10.7 1.3e-38 132.6 10.7 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 EGE01039.1 - 0.082 13.5 0.9 0.19 12.4 0.9 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 EGE01039.1 - 1.7 8.9 11.5 3.3 7.9 11.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Aminotran_5 PF00266.19 EGE01040.1 - 4.2e-29 101.6 0.0 6.9e-29 100.9 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class-V Peroxin-13_N PF04088.13 EGE01041.1 - 2.3e-53 180.4 0.1 4.1e-53 179.6 0.1 1.4 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EGE01041.1 - 6.9e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGE01041.1 - 2.3e-07 30.3 0.0 4.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE01041.1 - 9.9e-06 25.3 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EGE01041.1 - 0.21 12.0 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain GST_C PF00043.25 EGE01042.1 - 3.3e-09 36.9 0.0 5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE01042.1 - 1.1e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE01042.1 - 2.2e-05 24.6 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGE01042.1 - 0.00023 21.5 0.0 0.00056 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE01042.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGE01042.1 - 0.0034 17.7 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGE01042.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin ERO1 PF04137.15 EGE01043.1 - 2.4e-134 448.0 0.1 8e-134 446.3 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPP_enzyme_N PF02776.18 EGE01044.1 - 1.1e-44 152.1 0.1 2.3e-44 151.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGE01044.1 - 1.2e-34 119.0 0.0 2.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGE01044.1 - 2.2e-18 66.5 0.0 5e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 EGE01044.1 - 0.0097 15.9 0.5 0.033 14.2 0.1 2.1 2 0 0 2 2 2 1 B12 binding domain CO_dh PF02552.16 EGE01044.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPR_1 PF00515.28 EGE01045.1 - 1.1e-26 91.5 1.8 2.7e-09 36.4 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGE01045.1 - 1e-24 84.6 2.6 1.4e-07 31.0 0.0 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGE01045.1 - 1.2e-19 69.7 3.9 1.8e-08 33.9 0.0 4.9 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 EGE01045.1 - 2.2e-19 69.8 0.8 1.7e-05 25.3 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGE01045.1 - 3.2e-18 64.8 2.2 3.5e-05 24.3 0.0 5.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGE01045.1 - 2.4e-16 58.5 0.1 7.3e-07 28.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE01045.1 - 8.6e-16 58.2 2.3 0.00028 21.3 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGE01045.1 - 1.2e-15 56.7 1.7 0.0028 17.9 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 EGE01045.1 - 1.5e-10 41.2 0.5 0.0057 17.0 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE01045.1 - 2.1e-10 39.9 2.0 0.007 16.3 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE01045.1 - 2.5e-10 40.3 0.6 0.0041 17.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE01045.1 - 3.9e-10 39.9 4.5 8.6e-06 26.0 0.3 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGE01045.1 - 1.5e-07 31.6 1.1 2.4 9.0 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE01045.1 - 5.6e-06 26.5 1.3 0.0025 18.0 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGE01045.1 - 0.00024 20.4 0.4 0.29 10.3 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGE01045.1 - 0.0025 17.8 0.1 4.3 7.4 0.0 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 EGE01045.1 - 0.0065 16.5 0.5 10 6.3 0.1 4.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGE01045.1 - 0.013 15.3 4.1 0.084 12.8 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4192 PF13830.6 EGE01045.1 - 0.07 13.2 5.1 0.085 12.9 3.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) TOM20_plant PF06552.12 EGE01045.1 - 0.072 12.8 0.1 4.8 6.9 0.0 2.9 3 1 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF1641 PF07849.11 EGE01045.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) NatB_MDM20 PF09797.9 EGE01045.1 - 0.21 10.5 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit RRM_1 PF00076.22 EGE01046.1 - 2.7e-32 110.4 0.0 6.5e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGE01046.1 - 0.052 13.6 0.6 0.15 12.1 0.0 2.0 3 0 0 3 3 3 0 RNA binding motif RRM_7 PF16367.5 EGE01046.1 - 0.11 12.6 0.0 8.5 6.6 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif AID PF18767.1 EGE01046.1 - 0.17 11.9 0.0 4.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Activation induced deaminase Fungal_trans PF04082.18 EGE01047.1 - 1.4e-13 50.5 0.1 2.8e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01047.1 - 6.6e-07 29.3 12.4 1.5e-06 28.2 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 EGE01047.1 - 0.011 15.6 0.3 0.022 14.6 0.3 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SHS2_Rpb7-N PF03876.17 EGE01049.1 - 3.4e-14 52.9 0.1 5.3e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EGE01049.1 - 0.0005 20.3 0.0 0.00087 19.6 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 EGE01050.1 - 2.5e-26 91.6 0.0 4.3e-26 90.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.25 EGE01051.1 - 3.1e-73 246.0 0.0 4.5e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGE01051.1 - 1.7e-47 160.8 0.2 3e-47 160.1 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGE01051.1 - 5.3e-15 55.7 2.7 1.5e-14 54.3 2.7 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3659 PF12396.8 EGE01051.1 - 0.15 12.0 0.6 25 4.9 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3659) THF_DHG_CYH PF00763.23 EGE01052.1 - 7.2e-24 84.3 0.0 1.1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGE01052.1 - 9.8e-14 51.0 0.0 3.6e-09 36.1 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fer2_BFD PF04324.15 EGE01052.1 - 0.073 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain SPC25 PF06703.11 EGE01053.1 - 2.5e-48 163.9 0.5 2.9e-48 163.7 0.5 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) EMC3_TMCO1 PF01956.16 EGE01054.1 - 4.6e-53 179.4 0.9 5.6e-53 179.2 0.9 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like AmpE PF17113.5 EGE01054.1 - 0.081 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE Fasciclin PF02469.22 EGE01055.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain MMS19_C PF12460.8 EGE01056.1 - 1.1e-121 407.0 21.2 5.2e-120 401.4 16.0 4.1 3 2 1 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EGE01056.1 - 5.4e-62 209.7 1.6 2.8e-58 197.6 0.0 4.4 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 EGE01056.1 - 0.0038 17.6 4.5 1.4 9.3 0.3 4.7 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGE01056.1 - 5.1 7.1 6.7 9.6 6.2 0.0 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SHE3 PF17078.5 EGE01058.1 - 1.1e-08 35.1 26.9 9e-08 32.1 24.5 2.1 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 HSCB_C PF07743.13 EGE01058.1 - 0.046 14.2 0.8 0.046 14.2 0.8 3.7 1 1 3 4 4 4 0 HSCB C-terminal oligomerisation domain YjbH PF06082.11 EGE01058.1 - 0.21 10.3 5.4 0.24 10.1 5.4 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH KASH_CCD PF14662.6 EGE01058.1 - 0.63 9.9 29.7 5.2 6.9 7.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EGE01058.1 - 0.65 10.2 36.2 7.1 6.8 23.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DDHD PF02862.17 EGE01058.1 - 1.3 9.1 8.3 2 8.5 8.3 1.4 1 0 0 1 1 1 0 DDHD domain DUF3632 PF12311.8 EGE01059.1 - 5.8e-35 121.3 0.7 5.8e-35 121.3 0.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) GPI-anchored PF10342.9 EGE01060.1 - 3.8e-14 53.2 5.9 6.6e-14 52.4 0.0 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mcm10 PF09332.11 EGE01060.1 - 9.6 5.5 8.9 13 5.1 8.9 1.1 1 0 0 1 1 1 0 Mcm10 replication factor CBF PF03914.17 EGE01063.1 - 1.1e-35 123.1 0.3 3e-35 121.8 0.3 1.8 1 0 0 1 1 1 1 CBF/Mak21 family DUF2115 PF09888.9 EGE01063.1 - 0.0056 17.2 0.1 0.019 15.5 0.1 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2115) PRO8NT PF08082.11 EGE01063.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain DUF4806 PF16064.5 EGE01063.1 - 0.11 12.8 0.1 0.77 10.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Mt_ATP-synt_B PF05405.14 EGE01064.1 - 2.3e-50 170.4 9.7 2.8e-50 170.1 9.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.25 EGE01065.1 - 6.3e-21 74.9 0.0 1.8e-20 73.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01065.1 - 1.1e-09 38.0 0.0 0.0012 18.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Sel1 PF08238.12 EGE01066.1 - 1.2e-15 57.5 2.5 4.2e-06 27.2 0.3 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 EGE01066.1 - 0.0086 16.7 3.9 0.26 12.0 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat VPS9 PF02204.18 EGE01067.1 - 2.2e-27 95.3 0.0 3.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.25 EGE01068.1 - 5.7e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EGE01068.1 - 0.022 14.5 0.2 0.36 10.5 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.12 EGE01068.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EGE01068.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PAS_3 PF08447.12 EGE01069.1 - 1.6e-14 53.9 0.0 9.9e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EGE01069.1 - 7.1e-06 26.0 0.0 0.00014 21.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGE01069.1 - 2.2e-05 24.6 0.0 0.00014 22.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 EGE01069.1 - 3.4e-05 23.9 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGE01069.1 - 0.00024 21.3 0.0 0.00087 19.5 0.0 1.9 2 0 0 2 2 2 1 PAS fold DUF3419 PF11899.8 EGE01070.1 - 8.4e-159 528.9 0.0 1.2e-158 528.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EGE01070.1 - 1.2e-13 51.2 0.0 4.6e-13 49.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE01070.1 - 3.2e-12 47.0 0.0 1.5e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE01070.1 - 2.7e-11 44.1 0.0 1.4e-10 41.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE01070.1 - 4.2e-11 42.9 0.0 1.2e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE01070.1 - 1.8e-10 41.3 0.0 5.3e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE01070.1 - 1.8e-08 34.0 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGE01070.1 - 0.00048 19.9 0.0 0.00092 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGE01070.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE01070.1 - 0.01 15.3 0.0 0.75 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase Acetyltransf_1 PF00583.25 EGE01071.1 - 9e-11 42.0 0.0 1.7e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE01071.1 - 4.1e-10 39.7 0.0 1.8e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE01071.1 - 7e-10 39.2 0.0 1.5e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE01071.1 - 0.0001 22.4 0.0 0.00037 20.6 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE01071.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EGE01071.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase A_deaminase PF00962.22 EGE01072.1 - 8.8e-25 87.7 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase BTB PF00651.31 EGE01073.1 - 8.2e-16 58.2 0.1 3.8e-15 56.1 0.1 1.9 2 0 0 2 2 2 1 BTB/POZ domain RGS12_usC PF16612.5 EGE01073.1 - 0.089 13.2 0.4 10 6.5 0.1 2.3 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 adh_short PF00106.25 EGE01074.1 - 1.1e-31 109.8 0.6 1.7e-31 109.2 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE01074.1 - 6.9e-24 84.7 0.7 8.7e-24 84.4 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE01074.1 - 1.6e-09 37.9 0.2 2.3e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE01074.1 - 0.0022 17.5 0.1 0.0041 16.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE01074.1 - 0.0041 16.5 0.0 0.086 12.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AIRC PF00731.20 EGE01074.1 - 0.038 13.6 0.1 2.6 7.6 0.0 2.8 1 1 2 3 3 3 0 AIR carboxylase 3Beta_HSD PF01073.19 EGE01074.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGE01074.1 - 0.12 12.3 0.5 0.21 11.5 0.5 1.8 1 1 0 1 1 1 0 NAD(P)H-binding ECH_1 PF00378.20 EGE01076.1 - 5.7e-79 265.0 0.1 6.5e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE01076.1 - 6e-37 127.9 0.9 4.8e-34 118.3 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 EGE01077.1 - 1.4e-73 246.3 3.1 1.6e-73 246.1 3.1 1.0 1 0 0 1 1 1 1 Rer1 family Catalase PF00199.19 EGE01078.1 - 5.9e-195 647.8 0.0 7.4e-195 647.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGE01078.1 - 5e-12 45.9 0.0 1.2e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Ureidogly_lyase PF04115.12 EGE01079.1 - 3.8e-57 193.1 0.0 4.5e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase MutS_V PF00488.21 EGE01080.1 - 8e-73 244.5 0.0 1.4e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE01080.1 - 1.9e-43 148.9 2.8 1.9e-43 148.9 2.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGE01080.1 - 1.2e-22 80.3 0.0 3e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGE01080.1 - 3.1e-09 37.2 0.0 8.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 EGE01080.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EGE01080.1 - 0.058 13.0 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGE01080.1 - 0.062 13.8 1.5 0.34 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGE01080.1 - 0.075 13.1 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.16 EGE01081.1 - 3.2e-164 544.3 0.2 5.1e-93 310.9 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGE01081.1 - 2.8e-46 157.5 0.5 1.6e-27 96.4 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGE01081.1 - 2.3e-29 101.8 0.1 5.7e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EGE01081.1 - 2.7e-22 79.6 0.0 5e-13 49.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGE01081.1 - 1.1e-09 38.6 0.0 3.1e-07 30.7 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGE01081.1 - 1.1e-05 25.7 0.0 0.0033 17.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EGE01081.1 - 0.00096 18.7 0.0 0.052 13.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EGE01081.1 - 0.026 13.6 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGE01081.1 - 0.055 13.8 0.1 22 5.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain Peptidase_S9 PF00326.21 EGE01082.1 - 8.5e-23 80.9 0.0 1.6e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EGE01082.1 - 0.038 12.7 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RTC_insert PF05189.13 EGE01084.1 - 1.8e-31 108.7 0.0 7.1e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EGE01084.1 - 3.3e-27 95.1 0.1 4.1e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.12 EGE01085.1 - 3.2e-56 189.2 0.0 3.7e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGE01085.1 - 5.7e-05 22.7 0.1 8.3e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGE01085.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain CAP_GLY PF01302.25 EGE01086.1 - 2e-15 56.5 0.8 4.4e-15 55.4 0.2 1.9 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EGE01086.1 - 1.7e-07 31.0 9.6 4.9e-05 23.1 0.9 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle Fez1 PF06818.15 EGE01086.1 - 0.0013 19.3 23.1 0.065 13.7 14.1 3.0 2 1 1 3 3 3 2 Fez1 TolA_bind_tri PF16331.5 EGE01086.1 - 0.011 15.8 2.5 0.011 15.8 2.5 4.0 2 1 0 3 3 3 0 TolA binding protein trimerisation Spc7 PF08317.11 EGE01086.1 - 0.073 11.9 25.8 0.91 8.3 0.2 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 EGE01086.1 - 0.16 12.0 14.0 0.36 10.9 2.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 EGE01086.1 - 0.16 10.8 22.6 0.11 11.3 13.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 EGE01086.1 - 0.19 10.3 12.1 0.17 10.5 6.1 2.2 2 0 0 2 2 2 0 AAA domain C1_2 PF03107.16 EGE01086.1 - 0.45 10.9 2.1 15 6.0 0.1 2.4 2 0 0 2 2 2 0 C1 domain HMMR_N PF15905.5 EGE01086.1 - 0.6 9.5 25.8 2.6 7.4 0.6 2.6 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal EzrA PF06160.12 EGE01086.1 - 0.65 8.1 17.4 0.61 8.2 3.1 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA GIT_CC PF16559.5 EGE01086.1 - 0.72 9.8 5.9 9.2 6.2 2.1 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sec34 PF04136.15 EGE01086.1 - 1 9.2 8.1 1.6 8.6 2.9 2.3 2 0 0 2 2 2 0 Sec34-like family DUF745 PF05335.13 EGE01086.1 - 1.9 8.1 12.6 0.17 11.6 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF745) FAM76 PF16046.5 EGE01086.1 - 2.6 7.3 13.7 9 5.6 5.9 2.8 2 1 0 2 2 2 0 FAM76 protein DUF16 PF01519.16 EGE01086.1 - 3 8.4 12.6 2.6 8.6 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 EGE01086.1 - 3.4 8.3 12.9 32 5.2 0.0 3.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal PKcGMP_CC PF16808.5 EGE01086.1 - 4.1 7.3 27.5 0.24 11.3 2.3 4.6 5 0 0 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase NPV_P10 PF05531.12 EGE01086.1 - 5.7 7.5 13.6 53 4.4 0.1 4.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FliS PF02561.14 EGE01086.1 - 6.5 7.1 6.9 7.3 6.9 0.6 2.8 3 1 1 4 4 3 0 Flagellar protein FliS Pkinase PF00069.25 EGE01087.1 - 1.2e-34 119.9 0.0 1.4e-19 70.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01087.1 - 1.2e-11 44.4 0.0 5.9e-09 35.6 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGE01087.1 - 0.0051 16.2 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGE01087.1 - 0.0084 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3632 PF12311.8 EGE01088.1 - 1.7e-20 74.2 0.0 4.9e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) OPT PF03169.15 EGE01089.1 - 4.2e-77 260.2 45.4 1.1e-76 258.8 45.4 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein TssN PF17555.2 EGE01089.1 - 1.6 8.0 5.8 0.83 9.0 1.3 2.6 3 0 0 3 3 3 0 Type VI secretion system, TssN RBP_receptor PF14752.6 EGE01089.1 - 6.3 5.2 7.3 0.44 9.1 1.8 1.7 2 0 0 2 2 2 0 Retinol binding protein receptor PWWP PF00855.17 EGE01090.1 - 2.2e-15 56.8 7.3 2.2e-15 56.8 7.3 3.7 2 1 0 2 2 2 1 PWWP domain ComA PF02679.15 EGE01091.1 - 1.7e-87 292.9 0.0 2e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) SpoIIE PF07228.12 EGE01092.1 - 3.2e-11 43.5 0.1 1.1e-09 38.5 0.1 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGE01092.1 - 2.9e-07 30.3 0.2 6.9e-07 29.1 0.2 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EGE01092.1 - 4.9e-06 26.4 0.1 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.32 EGE01093.1 - 2.7e-33 113.5 22.1 2.4e-07 31.3 0.6 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 EGE01093.1 - 2.2e-14 52.7 0.8 4.2e-14 51.8 0.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGE01093.1 - 3e-11 43.5 0.1 0.026 14.8 0.0 5.7 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGE01093.1 - 0.0079 15.6 0.0 0.31 10.3 0.0 2.6 2 0 0 2 2 2 1 WD40-like domain Nbas_N PF15492.6 EGE01093.1 - 0.073 12.4 0.0 3.6 6.8 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal F-box-like PF12937.7 EGE01094.1 - 0.00027 20.8 0.5 0.00027 20.8 0.5 2.3 2 0 0 2 2 2 1 F-box-like ATP-synt_D PF01813.17 EGE01094.1 - 0.00097 19.0 0.1 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase subunit D F-box PF00646.33 EGE01094.1 - 0.023 14.6 1.0 0.023 14.6 1.0 1.8 2 0 0 2 2 2 0 F-box domain 3Beta_HSD PF01073.19 EGE01095.1 - 2.8e-08 33.1 0.1 6.1e-08 32.0 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGE01095.1 - 5.5e-05 22.8 0.1 0.00019 21.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGE01095.1 - 9.8e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGE01095.1 - 0.024 13.8 0.0 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein HSCB_C PF07743.13 EGE01096.1 - 9.6e-19 67.7 1.9 1.4e-18 67.1 0.5 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGE01096.1 - 4.7e-05 23.4 0.1 0.00022 21.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain DUF4352 PF11611.8 EGE01096.1 - 0.077 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) SHD1 PF03983.12 EGE01098.1 - 2e-33 114.0 0.0 3.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EGE01098.1 - 3e-32 110.0 4.7 1.8e-11 43.5 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EGE01098.1 - 5.5e-30 103.0 5.8 2.9e-11 43.1 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EGE01098.1 - 4.6e-21 74.2 0.4 6.6e-08 32.1 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 EGE01098.1 - 4.5e-05 23.3 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EGE01098.1 - 0.044 13.8 0.9 2.2 8.4 0.0 3.2 4 0 0 4 4 4 0 SH3 domain PRKCSH PF07915.13 EGE01099.1 - 3.6e-18 66.3 0.1 3.6e-18 66.3 0.1 3.0 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein STT3 PF02516.14 EGE01100.1 - 8e-148 493.4 33.0 1e-141 473.2 33.2 2.4 3 0 0 3 3 3 2 Oligosaccharyl transferase STT3 subunit APH PF01636.23 EGE01102.1 - 6.5e-18 65.5 0.0 1e-17 64.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE01102.1 - 0.0003 20.2 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGE01102.1 - 0.0016 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGE01102.1 - 0.064 12.8 0.0 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 EGE01102.1 - 0.084 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pirin PF02678.16 EGE01103.1 - 9.5e-30 102.8 0.1 1.9e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGE01103.1 - 5.3e-25 87.8 0.0 1.6e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGE01103.1 - 0.00011 21.9 1.2 0.0018 18.0 1.0 2.4 2 1 0 2 2 2 1 Cupin domain PMT PF02366.18 EGE01104.1 - 1.5e-80 270.3 15.1 1.9e-78 263.5 15.1 2.4 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGE01104.1 - 3.5e-69 232.4 2.6 3.5e-69 232.4 2.6 3.1 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGE01104.1 - 6.8e-06 26.0 0.1 0.00058 19.8 0.1 2.2 1 1 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EGE01104.1 - 0.0036 17.5 3.7 0.0036 17.5 3.7 3.1 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Synthase_beta PF11421.8 EGE01105.1 - 0.05 14.3 0.5 0.16 12.7 0.5 1.8 1 0 0 1 1 1 0 ATP synthase F1 beta subunit WD40 PF00400.32 EGE01106.1 - 0.00042 21.1 12.0 2.2 9.3 0.1 5.9 6 1 0 6 6 6 3 WD domain, G-beta repeat ATP-synt_E PF05680.12 EGE01107.1 - 6.9e-23 80.8 0.2 7.1e-23 80.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.13 EGE01107.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain CSN8_PSD8_EIF3K PF10075.9 EGE01108.1 - 4.2e-15 56.0 0.0 6.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EGE01108.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.8 1 1 0 1 1 1 0 PCI domain DUF3453 PF11935.8 EGE01109.1 - 2.5e-68 230.1 2.6 2.5e-68 230.1 2.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) SMN PF06003.12 EGE01109.1 - 0.099 11.9 2.5 0.2 10.9 2.5 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Coiled-coil_56 PF09813.9 EGE01110.1 - 0.0074 16.3 0.0 0.0094 16.0 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Sds3 PF08598.11 EGE01111.1 - 4.8e-12 46.3 0.9 4.8e-12 46.3 0.9 2.3 2 0 0 2 2 2 1 Sds3-like DUF4940 PF16298.5 EGE01111.1 - 0.034 13.8 0.1 0.66 9.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4940) APH PF01636.23 EGE01113.1 - 8.1e-12 45.6 0.0 1.2e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE01113.1 - 0.0019 17.8 0.0 0.055 13.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EGE01113.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGE01113.1 - 0.058 12.6 0.0 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 EGE01113.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RRM_1 PF00076.22 EGE01114.1 - 2.6e-11 43.2 0.5 2.6e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.13 EGE01114.1 - 1.7 8.2 22.5 0.31 10.6 17.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) GREB1 PF15782.5 EGE01114.1 - 2.9 4.9 9.2 3.7 4.6 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GPI-anchored PF10342.9 EGE01115.1 - 2.3e-19 70.0 0.2 2.3e-19 70.0 0.2 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.9 EGE01115.1 - 0.44 9.7 18.7 0.49 9.5 18.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 EGE01115.1 - 1.3 7.7 4.6 1.6 7.4 4.6 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGE01115.1 - 5.9 5.3 10.8 7.3 5.0 10.8 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGE01115.1 - 8.8 5.1 14.1 11 4.8 14.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain NUFIP1 PF10453.9 EGE01116.1 - 6.8e-11 41.8 6.0 6.8e-11 41.8 6.0 4.3 2 1 1 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EGE01116.1 - 5.3e-07 29.4 5.8 8.7e-07 28.7 5.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE01116.1 - 0.0001 22.2 5.0 0.00018 21.4 5.0 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGE01116.1 - 0.0083 15.9 4.1 0.013 15.3 4.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger RNA_pol_Rbc25 PF08292.12 EGE01117.1 - 5.8e-35 120.4 1.1 2.1e-34 118.5 1.1 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGE01117.1 - 1.1e-15 57.7 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.20 EGE01118.1 - 6e-136 452.9 0.0 6.9e-136 452.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGE01118.1 - 8.8e-06 25.1 0.1 1.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGE01118.1 - 0.0049 16.2 0.5 0.012 14.9 0.5 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGE01118.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EGE01118.1 - 0.014 14.4 0.7 0.018 14.0 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Crinivirus_P26 PF07416.11 EGE01118.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Crinivirus P26 protein Peptidase_M36 PF02128.15 EGE01119.1 - 3.9e-160 533.1 5.4 5e-160 532.7 5.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGE01119.1 - 1.5e-16 60.0 1.5 3.1e-16 58.9 1.5 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGE01119.1 - 0.07 13.0 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Methyltransf_16 PF10294.9 EGE01120.1 - 0.03 14.1 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Lysine methyltransferase Filament PF00038.21 EGE01122.1 - 0.00034 20.3 48.2 0.00034 20.3 48.2 3.7 3 1 1 4 4 4 1 Intermediate filament protein OEP PF02321.18 EGE01123.1 - 0.00052 19.9 3.0 0.0011 18.8 3.0 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein zf-C2H2 PF00096.26 EGE01123.1 - 0.0039 17.6 26.0 0.099 13.1 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 EGE01123.1 - 0.018 15.7 1.5 0.018 15.7 1.5 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain PapD_N PF00345.20 EGE01123.1 - 0.048 13.6 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Peptidase_S8 PF00082.22 EGE01124.1 - 4.5e-25 88.5 6.3 7e-25 87.9 5.0 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE01124.1 - 1.7e-13 51.1 0.3 2.9e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 CLN3 PF02487.17 EGE01124.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein zf-C2H2 PF00096.26 EGE01125.1 - 0.0081 16.6 40.7 0.017 15.5 0.7 6.5 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGE01125.1 - 0.75 10.1 13.7 0.13 12.6 0.7 3.2 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EGE01125.1 - 1.6 9.1 16.8 2.3 8.6 1.5 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EGE01125.1 - 7.1 6.7 7.7 0.88 9.7 0.5 2.8 2 1 1 3 3 3 0 Aberrant zinc-finger Carb_kinase PF01256.17 EGE01126.1 - 6.4e-56 189.6 0.1 7.7e-55 186.0 0.0 1.9 2 0 0 2 2 2 2 Carbohydrate kinase SPT2 PF08243.11 EGE01127.1 - 8.6e-12 45.6 11.5 8.6e-12 45.6 11.5 2.2 2 0 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 EGE01128.1 - 2.1e-26 92.3 8.2 2.5e-26 92.1 8.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_r1_1 PF03979.14 EGE01128.1 - 0.54 10.4 0.1 0.54 10.4 0.1 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Ribosomal_S19 PF00203.21 EGE01129.1 - 5.4e-33 112.7 0.3 7.4e-33 112.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SET PF00856.28 EGE01130.1 - 7.1e-15 55.8 0.1 6.6e-14 52.6 0.1 2.2 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGE01130.1 - 4.5e-10 39.5 6.6 4.5e-10 39.5 6.6 2.1 2 0 0 2 2 2 1 MYND finger Rtf2 PF04641.12 EGE01130.1 - 0.03 13.7 0.5 0.053 12.9 0.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger V-ATPase_G PF03179.15 EGE01130.1 - 3.8 8.1 6.1 0.68 10.5 2.2 1.8 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Pkinase PF00069.25 EGE01131.1 - 4.3e-08 32.8 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01131.1 - 3e-06 26.7 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAM178 PF14816.6 EGE01131.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 RuvA_C PF07499.13 EGE01131.1 - 0.14 12.7 0.1 0.24 11.9 0.1 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain PRANC PF09372.10 EGE01132.1 - 0.17 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 PRANC domain CPSase_L_D2 PF02786.17 EGE01133.1 - 8.9e-107 355.4 0.0 2e-83 279.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EGE01133.1 - 1.7e-41 141.4 0.1 4.3e-41 140.1 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EGE01133.1 - 1.6e-17 63.6 0.0 1.7e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGE01133.1 - 9.5e-16 57.9 0.1 7.7e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGE01133.1 - 5.5e-10 39.1 0.0 0.0013 18.5 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 EGE01133.1 - 2.1e-05 24.2 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EGE01133.1 - 0.00013 21.5 0.0 0.024 14.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EGE01133.1 - 0.00045 20.0 0.0 0.062 13.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPX PF03105.19 EGE01135.1 - 0.013 15.4 5.5 0.016 15.2 5.5 1.2 1 0 0 1 1 1 0 SPX domain Retinal PF15449.6 EGE01135.1 - 9.7 3.8 37.3 13 3.5 37.3 1.0 1 0 0 1 1 1 0 Retinal protein DUF4187 PF13821.6 EGE01136.1 - 5.6e-22 77.3 0.9 5.6e-22 77.3 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) SNURF PF07192.11 EGE01136.1 - 0.12 12.3 0.6 2 8.3 0.0 2.2 2 0 0 2 2 2 0 SNURF/RPN4 protein G-patch PF01585.23 EGE01137.1 - 7.9e-11 41.7 1.8 2.9e-09 36.7 1.8 2.3 1 1 0 1 1 1 1 G-patch domain PALP PF00291.25 EGE01138.1 - 7.8e-38 130.5 0.1 9.8e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CDP-OH_P_transf PF01066.21 EGE01139.1 - 1.3e-12 48.3 0.0 1.3e-12 48.3 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M1_N PF17900.1 EGE01140.1 - 0.003 17.8 0.1 2.9 8.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EGE01140.1 - 0.0056 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain LSM PF01423.22 EGE01141.1 - 5.3e-23 80.5 0.5 5.9e-23 80.4 0.5 1.0 1 0 0 1 1 1 1 LSM domain OrfB_IS605 PF01385.19 EGE01142.1 - 0.4 10.9 2.9 8.8 6.6 0.1 2.8 1 1 1 2 2 2 0 Probable transposase Nup54 PF13874.6 EGE01142.1 - 0.42 10.7 7.7 0.37 10.9 1.4 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 zf-C4H2 PF10146.9 EGE01142.1 - 5.1 7.3 12.4 0.041 14.2 2.5 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein LtrA PF06772.11 EGE01143.1 - 1.2e-21 77.3 20.6 1.2e-21 77.3 20.6 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) adh_short PF00106.25 EGE01144.1 - 6.3e-28 97.6 0.6 2.7e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGE01144.1 - 2e-20 73.4 0.1 1.9e-18 66.9 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE01144.1 - 3.8e-05 23.7 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DSBA PF01323.20 EGE01145.1 - 5.1e-18 65.5 0.0 5.8e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain RPN7 PF10602.9 EGE01146.1 - 1.8e-50 171.1 0.1 3.1e-50 170.3 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGE01146.1 - 2.3e-10 40.9 0.1 6.7e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 PCI domain Band_7 PF01145.25 EGE01146.1 - 0.13 12.2 0.5 0.27 11.2 0.5 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family zf-C2H2 PF00096.26 EGE01147.1 - 0.00028 21.2 21.4 0.54 10.8 1.0 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE01147.1 - 0.06 14.2 19.7 0.98 10.4 0.6 5.2 4 1 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 EGE01147.1 - 1.8 9.2 5.4 27 5.5 0.4 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain ATP_transf PF09830.9 EGE01148.1 - 1.5e-23 82.7 0.2 2.7e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 EGE01148.1 - 0.058 14.1 0.1 0.12 13.1 0.1 1.6 1 0 0 1 1 1 0 HIT domain DUF4931 PF16285.5 EGE01148.1 - 0.076 12.3 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) E1_4HB PF16191.5 EGE01148.1 - 0.098 12.9 0.7 0.27 11.5 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Myb_DNA-bind_4 PF13837.6 EGE01149.1 - 0.049 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.16 EGE01150.1 - 9e-21 74.2 35.8 4.6e-11 42.2 7.2 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 EGE01150.1 - 2.9e-07 29.5 1.3 2e-05 23.4 0.0 2.9 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EGE01150.1 - 8.5e-07 28.2 6.1 0.0069 15.3 0.1 3.3 3 0 0 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 EGE01150.1 - 9.4e-05 21.1 6.0 9.4e-05 21.1 6.0 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.19 EGE01150.1 - 0.018 13.8 11.9 0.033 13.0 1.9 3.2 3 0 0 3 3 3 0 LacY proton/sugar symporter zf-rbx1 PF12678.7 EGE01151.1 - 4.9e-09 36.3 3.1 1.1e-08 35.2 3.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGE01151.1 - 1.8e-07 31.4 2.8 1.8e-07 31.4 2.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGE01151.1 - 2.3e-07 30.5 0.2 5.1e-07 29.5 0.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE01151.1 - 8.3e-06 25.6 5.6 4e-05 23.4 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE01151.1 - 5.1e-05 23.2 0.8 0.00011 22.2 0.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGE01151.1 - 0.00013 21.7 3.1 0.00013 21.7 3.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE01151.1 - 0.00028 20.8 1.5 0.0017 18.3 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGE01151.1 - 0.00064 19.3 0.7 0.0013 18.4 0.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGE01151.1 - 0.0035 17.2 0.8 0.0035 17.2 0.8 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGE01151.1 - 0.0041 17.1 5.0 0.066 13.3 5.0 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YacG PF03884.14 EGE01151.1 - 0.02 14.6 0.4 0.056 13.2 0.4 1.8 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-RING_11 PF17123.5 EGE01151.1 - 0.2 11.4 2.5 0.78 9.5 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger MCM_bind PF09739.9 EGE01151.1 - 1.8 7.0 4.1 2.8 6.3 4.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NOA36 PF06524.12 EGE01151.1 - 2.1 7.6 14.0 4.5 6.5 14.0 1.5 1 0 0 1 1 1 0 NOA36 protein zf-RING_4 PF14570.6 EGE01151.1 - 3 7.7 4.4 1.1 9.1 1.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SurE PF01975.17 EGE01152.1 - 7.4e-36 123.7 0.1 9.9e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE DUF3431 PF11913.8 EGE01153.1 - 3.2e-83 278.8 0.0 4.4e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF116 PF01976.17 EGE01154.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF116 DnaJ PF00226.31 EGE01155.1 - 1.1e-20 73.5 0.5 3.6e-20 71.8 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain Trypan_PARP PF05887.11 EGE01155.1 - 0.00013 21.9 15.9 0.00013 21.9 15.9 2.2 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) zf-B_box PF00643.24 EGE01155.1 - 0.029 14.5 1.9 0.056 13.6 1.9 1.5 1 0 0 1 1 1 0 B-box zinc finger Zn_ribbon_17 PF17120.5 EGE01155.1 - 0.037 13.6 2.1 0.064 12.9 2.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FYVE PF01363.21 EGE01155.1 - 0.57 10.4 5.3 0.53 10.5 3.5 1.9 2 0 0 2 2 2 0 FYVE zinc finger tRNA-synt_1 PF00133.22 EGE01157.1 - 6.4e-201 668.7 2.1 4.7e-199 662.5 2.1 2.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGE01157.1 - 7.9e-34 116.8 0.5 7.9e-34 116.8 0.5 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EGE01157.1 - 3.7e-09 36.4 4.0 5.8e-06 26.0 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGE01157.1 - 2e-07 30.1 0.6 0.18 10.6 0.2 4.0 3 1 1 4 4 4 3 tRNA synthetases class I (M) PepSY PF03413.19 EGE01157.1 - 0.031 14.8 1.9 0.16 12.6 0.0 2.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain tRNA-synt_1e PF01406.19 EGE01157.1 - 0.083 12.2 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain TPR_12 PF13424.6 EGE01159.1 - 0.076 13.3 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGE01161.1 - 2.1e-17 63.4 0.0 2.8e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01161.1 - 1.3e-08 34.4 0.0 2.1e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE01161.1 - 0.0024 17.8 0.8 0.05 13.5 0.8 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE01161.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGE01161.1 - 0.037 12.8 1.0 0.058 12.2 1.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGE01161.1 - 0.12 11.3 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EGE01162.1 - 4.6e-65 219.6 0.0 5.4e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01162.1 - 2.1e-19 69.8 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE01162.1 - 6.4e-09 36.1 0.7 0.00012 22.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE01162.1 - 0.0033 16.3 0.1 0.008 15.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGE01162.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE01162.1 - 0.03 13.6 0.0 0.052 12.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGE01162.1 - 0.041 13.5 1.1 0.06 12.9 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Methyltransf_2 PF00891.18 EGE01163.1 - 2.2e-24 86.0 0.0 3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGE01163.1 - 0.045 14.4 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGE01163.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGE01163.1 - 0.21 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 EGE01164.1 - 1.9e-49 168.4 0.0 2.7e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EGE01164.1 - 5.6e-27 95.3 0.1 3.3e-26 92.8 0.1 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EGE01164.1 - 3.4e-10 40.1 0.1 9e-10 38.8 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_1 PF00561.20 EGE01164.1 - 5.3e-06 26.3 0.0 9.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE01164.1 - 0.00013 21.3 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE01164.1 - 0.00022 21.9 0.2 0.00045 20.9 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_2 PF00891.18 EGE01165.1 - 2.1e-20 72.9 0.0 3e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGE01165.1 - 0.00034 20.5 0.1 0.00087 19.2 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain Dimerisation PF08100.11 EGE01165.1 - 0.012 15.6 0.0 0.051 13.6 0.0 2.2 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.22 EGE01166.1 - 5.6e-60 203.4 0.0 7.5e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M56 PF05569.11 EGE01167.1 - 2.9 7.0 8.3 0.51 9.5 3.6 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 MFS_1 PF07690.16 EGE01168.1 - 3.3e-30 105.2 67.4 3.5e-28 98.5 40.7 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01168.1 - 7.2e-11 41.6 6.8 7.2e-11 41.6 6.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGE01168.1 - 4.1e-08 32.1 6.7 4.1e-08 32.1 6.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3493 PF11998.8 EGE01168.1 - 0.1 12.8 5.7 1.7 8.8 0.5 4.3 4 0 0 4 4 4 0 Low psii accumulation1 / Rep27 DUF4235 PF14019.6 EGE01168.1 - 0.13 12.3 2.6 2.4 8.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) NmrA PF05368.13 EGE01169.1 - 8.1e-30 104.1 0.0 1.5e-29 103.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE01169.1 - 1.3e-19 70.8 0.0 2.1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGE01169.1 - 0.05 13.1 0.0 0.15 11.5 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EGE01170.1 - 7.5e-22 77.7 0.0 1.4e-21 76.8 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.11 EGE01170.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal EamA PF00892.20 EGE01170.1 - 0.57 10.3 6.1 5.1 7.3 1.7 2.3 2 0 0 2 2 2 0 EamA-like transporter family RNase_P_p30 PF01876.16 EGE01171.1 - 6.3e-66 221.9 0.0 7.9e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 F-box PF00646.33 EGE01172.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGE01172.1 - 0.00027 20.8 0.0 0.00069 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.7 EGE01174.1 - 2.6e-21 77.3 0.1 3.3e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE01174.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGE01174.1 - 0.037 13.7 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S9 PF00326.21 EGE01174.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Frigida PF07899.11 EGE01174.1 - 0.099 11.9 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein Abhydrolase_8 PF06259.12 EGE01174.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase VirB8 PF04335.13 EGE01174.1 - 0.24 11.2 0.0 0.39 10.5 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein A_deaminase PF00962.22 EGE01176.1 - 8.6e-123 409.8 0.0 1.2e-122 409.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 EGE01177.1 - 4.5e-27 95.1 0.0 2.4e-26 92.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01177.1 - 3.1e-14 52.9 0.0 6.9e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01177.1 - 0.0033 16.3 0.0 0.064 12.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase FGGY_C PF02782.16 EGE01178.1 - 1.3e-70 237.2 1.5 1.5e-70 237.0 0.6 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGE01178.1 - 1.8e-69 234.0 0.0 2.6e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 EGE01179.1 - 4.9e-58 196.5 3.8 6.3e-58 196.2 3.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2644 PF10841.8 EGE01179.1 - 1.8 8.8 5.3 0.91 9.8 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) Peptidase_S8 PF00082.22 EGE01181.1 - 3e-31 108.8 1.2 4.7e-31 108.2 1.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE01181.1 - 5.3e-13 49.4 0.0 8.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 Rap_GAP PF02145.15 EGE01181.1 - 0.053 13.1 0.0 0.44 10.1 0.0 2.0 2 0 0 2 2 2 0 Rap/ran-GAP Peptidase_S10 PF00450.22 EGE01183.1 - 3.8e-82 276.9 0.0 4.9e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3752 PF12572.8 EGE01184.1 - 1.6e-46 158.6 13.9 1.6e-46 158.6 13.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) JHY PF15261.6 EGE01184.1 - 1.4 9.6 12.7 0.14 12.8 7.5 2.0 2 0 0 2 2 2 0 Jhy protein tRNA-synt_2c PF01411.19 EGE01186.1 - 9.8e-218 724.1 0.0 1.5e-217 723.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGE01186.1 - 5e-18 64.9 0.6 1.3e-17 63.5 0.6 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EGE01186.1 - 1.9e-14 54.2 1.3 1.9e-14 54.2 1.3 2.2 2 0 0 2 2 2 1 DHHA1 domain Pro_isomerase PF00160.21 EGE01187.1 - 9.3e-51 172.2 0.5 1.1e-50 172.0 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD OAD_gamma PF04277.13 EGE01190.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3844 PF12955.7 EGE01191.1 - 3.3e-36 123.6 4.3 5.7e-36 122.8 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Thioredoxin_4 PF13462.6 EGE01193.1 - 5.2e-11 43.0 0.1 7.7e-10 39.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin UPF0020 PF01170.18 EGE01193.1 - 0.048 13.3 0.1 0.087 12.5 0.1 1.4 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DSBA PF01323.20 EGE01193.1 - 0.33 10.7 4.1 0.89 9.3 0.2 2.5 1 1 1 2 2 2 0 DSBA-like thioredoxin domain CKS PF01111.19 EGE01194.1 - 3e-34 117.1 1.4 3e-34 117.1 1.4 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 EGE01195.1 - 5.1e-29 100.2 1.9 4e-16 58.9 0.1 3.2 3 0 0 3 3 3 2 Bromodomain QRPTase_C PF01729.19 EGE01195.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain K_channel_TID PF07941.11 EGE01195.1 - 2.2 8.8 4.7 1.1 9.8 1.2 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HSP70 PF00012.20 EGE01196.1 - 8.9e-227 754.0 8.2 1e-226 753.9 8.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGE01196.1 - 6.9e-16 58.0 0.6 4.6e-15 55.3 0.3 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGE01196.1 - 9.9e-05 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EGE01196.1 - 0.03 13.3 0.1 0.39 9.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DevR PF01905.16 EGE01196.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 MscS_porin PF12795.7 EGE01196.1 - 0.29 10.7 2.8 0.18 11.3 0.4 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain RRF PF01765.19 EGE01197.1 - 6.8e-46 156.2 1.5 9.4e-46 155.7 1.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Guanylate_kin PF00625.21 EGE01197.1 - 0.038 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase FliG_N PF14842.6 EGE01197.1 - 0.065 13.8 0.8 0.19 12.3 0.4 2.0 2 1 1 3 3 3 0 FliG N-terminal domain Fungal_trans PF04082.18 EGE01199.1 - 1.4e-07 30.8 0.8 2.6e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01199.1 - 2.1e-05 24.5 7.9 3.8e-05 23.7 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 EGE01200.1 - 9.5e-09 35.3 0.2 2.5e-08 34.0 0.0 1.8 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein Pheromone PF08015.11 EGE01200.1 - 0.2 12.7 0.6 0.96 10.5 0.0 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone adh_short_C2 PF13561.6 EGE01201.1 - 9.1e-48 162.8 1.7 2e-47 161.7 1.7 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE01201.1 - 6.2e-38 130.2 0.4 1.6e-37 128.9 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EGE01201.1 - 1.1e-06 28.2 0.3 3e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGE01201.1 - 9.4e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EGE01201.1 - 0.00019 20.9 0.1 0.0058 16.1 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EGE01201.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 EGE01201.1 - 0.0024 17.8 1.9 0.0026 17.7 0.6 2.0 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EGE01201.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EGE01201.1 - 0.043 14.4 0.0 0.098 13.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EGE01201.1 - 0.16 10.9 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Chromate_transp PF02417.15 EGE01202.1 - 8.6e-60 201.4 36.1 5.9e-35 120.7 13.8 2.5 3 0 0 3 3 3 2 Chromate transporter GTP_EFTU PF00009.27 EGE01203.1 - 3.8e-47 160.3 0.0 6e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EGE01203.1 - 5.5e-37 127.1 7.8 9.7e-37 126.3 7.8 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EGE01203.1 - 3.4e-21 75.3 0.0 1e-20 73.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGE01203.1 - 1.5e-19 69.8 0.0 5.1e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGE01203.1 - 1.3e-10 41.5 0.0 3.4e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGE01203.1 - 4.1e-07 30.0 0.1 1.2e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGE01203.1 - 1.3e-05 25.2 0.1 2.5e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGE01203.1 - 0.098 12.1 0.1 1.1 8.7 0.1 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF5505 PF17610.2 EGE01203.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Septin PF00735.18 EGE01203.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Septin LysM PF01476.20 EGE01204.1 - 2e-13 50.2 0.0 2e-05 24.5 0.0 4.2 4 0 0 4 4 4 3 LysM domain Rab15_effector PF15208.6 EGE01204.1 - 0.0069 15.7 0.1 2.8 7.2 0.0 2.5 2 1 0 3 3 3 2 Rab15 effector UPF0203 PF05254.12 EGE01204.1 - 0.0092 16.2 9.5 4.4 7.6 0.0 4.6 4 2 0 4 4 4 2 Uncharacterised protein family (UPF0203) CarbpepA_inh PF02977.15 EGE01204.1 - 0.014 15.2 5.1 17 5.3 0.0 5.1 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Phage_GPL PF05926.11 EGE01204.1 - 0.28 11.2 0.0 2.5 8.1 0.0 2.0 2 0 0 2 2 2 0 Phage head completion protein (GPL) Thiolase_N PF00108.23 EGE01205.1 - 6.9e-93 310.7 0.2 1.1e-92 310.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE01205.1 - 3.8e-44 149.3 2.0 8.1e-44 148.2 1.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGE01205.1 - 1.8e-05 24.4 2.8 3.1e-05 23.7 1.4 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGE01205.1 - 0.065 13.1 1.5 2.2 8.2 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zip PF02535.22 EGE01206.1 - 2e-50 171.9 7.1 4.6e-50 170.7 7.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter KRTAP PF11759.8 EGE01206.1 - 0.11 13.1 2.1 0.29 11.7 2.1 1.7 1 0 0 1 1 1 0 Keratin-associated matrix DUF2401 PF10287.9 EGE01207.1 - 1.8e-75 253.5 0.0 2.7e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EGE01207.1 - 2.1e-21 76.1 0.2 5.6e-21 74.7 0.2 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Pkinase PF00069.25 EGE01208.1 - 1.6e-08 34.2 0.0 3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01208.1 - 3.8e-07 29.7 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGE01208.1 - 0.0029 17.2 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Atg14 PF10186.9 EGE01210.1 - 1e-85 287.6 0.0 1.4e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BBP1_C PF15272.6 EGE01210.1 - 0.078 12.8 4.2 0.13 12.1 4.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Filament PF00038.21 EGE01210.1 - 0.24 10.9 6.7 1.8 8.1 7.4 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF1192 PF06698.11 EGE01210.1 - 0.33 11.1 3.5 1 9.5 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 EGE01210.1 - 0.37 10.8 1.5 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF4200 PF13863.6 EGE01210.1 - 1.7 9.1 6.4 2.9 8.3 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) SLATT_1 PF18181.1 EGE01211.1 - 0.041 13.8 1.8 0.058 13.3 0.9 1.6 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 CREPT PF16566.5 EGE01211.1 - 0.46 10.6 4.0 1.1 9.5 4.0 1.5 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour LMBR1 PF04791.16 EGE01212.1 - 7.5e-17 61.4 5.1 7.5e-17 61.4 5.1 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF5367 PF17329.2 EGE01212.1 - 0.028 14.5 2.2 0.028 14.5 2.2 4.4 7 0 0 7 7 7 0 Family of unknown function (DUF5367) PHINT_rpt PF14882.6 EGE01213.1 - 0.0039 17.4 0.1 0.0082 16.4 0.1 1.5 1 0 0 1 1 1 1 Phage-integrase repeat unit NTP_transf_5 PF14907.6 EGE01213.1 - 0.042 13.5 0.6 0.34 10.5 0.6 2.0 1 1 0 1 1 1 0 Uncharacterised nucleotidyltransferase DUF4470 PF14737.6 EGE01214.1 - 5.9e-25 87.3 0.1 1.5e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EGE01214.1 - 9.9e-11 41.6 10.2 2e-10 40.5 10.2 1.6 1 0 0 1 1 1 1 MYND finger FlxA PF14282.6 EGE01216.1 - 0.28 11.2 1.5 7.4 6.6 1.1 2.4 2 0 0 2 2 2 0 FlxA-like protein PIG-F PF06699.11 EGE01217.1 - 1.5e-65 220.7 7.0 1.7e-65 220.5 7.0 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F ATPase_gene1 PF09527.10 EGE01217.1 - 2.3 8.4 10.7 0.19 11.9 4.0 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Gly-zipper_OmpA PF13436.6 EGE01217.1 - 5.5 6.9 12.2 3.2 7.6 0.6 3.5 3 0 0 3 3 3 0 Glycine-zipper domain Amidase PF01425.21 EGE01218.1 - 1.2e-92 311.2 0.0 2.2e-91 307.1 0.0 2.0 1 1 0 1 1 1 1 Amidase ADH_N PF08240.12 EGE01219.1 - 1.2e-26 92.8 0.8 2.8e-26 91.5 0.8 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE01219.1 - 7.3e-19 68.0 0.2 1.4e-18 67.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGE01219.1 - 0.00028 20.3 0.7 0.00048 19.5 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EGE01219.1 - 0.0078 16.5 0.2 0.029 14.6 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain zf-Tim10_DDP PF02953.15 EGE01220.1 - 4.5e-16 58.3 3.7 4.5e-16 58.3 3.7 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger YqzH PF14164.6 EGE01220.1 - 0.043 13.9 1.1 0.15 12.2 0.7 2.1 2 1 0 2 2 2 0 YqzH-like protein Pkinase PF00069.25 EGE01221.1 - 3.3e-25 88.9 0.0 1.6e-24 86.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01221.1 - 1.9e-08 33.9 0.1 1.5e-07 30.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE01224.1 - 1e-09 38.7 0.0 6.7e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_PK PF05891.12 EGE01226.1 - 2.6e-66 223.3 0.0 3e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 EGE01226.1 - 1.2e-05 25.8 0.1 4.4e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE01226.1 - 3e-05 23.9 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE01226.1 - 6.2e-05 23.6 0.1 0.00037 21.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGE01226.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain WD40 PF00400.32 EGE01227.1 - 7.3e-116 374.8 75.5 6.5e-10 39.4 0.6 14.6 15 0 0 15 15 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE01227.1 - 2.2e-35 120.8 22.3 0.0032 17.7 0.1 12.6 1 1 11 12 12 12 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE01227.1 - 8.6e-20 70.9 31.3 0.02 13.6 0.0 10.8 4 3 7 11 11 11 8 Nucleoporin Nup120/160 NACHT PF05729.12 EGE01227.1 - 8.3e-19 68.1 0.0 1.6e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 EGE01227.1 - 1.1e-14 54.8 0.7 4.9e-06 27.0 0.0 4.3 3 2 2 5 5 4 2 Ankyrin repeats (3 copies) eIF2A PF08662.11 EGE01227.1 - 2.4e-10 40.6 6.5 0.0031 17.4 0.1 4.9 4 2 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ank_4 PF13637.6 EGE01227.1 - 3.4e-09 37.0 0.0 0.00075 20.0 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ge1_WD40 PF16529.5 EGE01227.1 - 3.3e-08 32.9 21.3 0.0088 15.0 2.2 8.3 1 1 5 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ank PF00023.30 EGE01227.1 - 8.3e-08 32.3 0.2 0.024 15.1 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGE01227.1 - 1.3e-07 31.7 0.0 0.011 16.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE01227.1 - 2.2e-07 30.6 0.0 0.004 17.5 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat WD40_like PF17005.5 EGE01227.1 - 6.7e-07 28.9 2.1 0.11 11.9 0.1 4.6 5 0 0 5 5 5 2 WD40-like domain Nucleoporin_N PF08801.11 EGE01227.1 - 6.8e-06 25.1 18.9 0.029 13.1 0.1 6.2 2 2 1 5 5 5 2 Nup133 N terminal like AAA_16 PF13191.6 EGE01227.1 - 6.4e-05 23.4 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain HPS3_N PF14761.6 EGE01227.1 - 0.00021 20.9 0.0 2.2 7.8 0.0 4.2 4 0 0 4 4 4 1 Hermansky-Pudlak syndrome 3 NACHT_sigma PF17106.5 EGE01227.1 - 0.0014 18.8 1.8 0.0029 17.7 1.8 1.5 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Cytochrom_D1 PF02239.16 EGE01227.1 - 0.0081 14.7 10.4 0.55 8.7 0.4 4.2 2 1 3 6 6 6 3 Cytochrome D1 heme domain DUF5046 PF16465.5 EGE01227.1 - 0.047 13.1 0.2 0.5 9.8 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) AAA_19 PF13245.6 EGE01227.1 - 0.079 13.3 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Shigella_OspC PF06128.11 EGE01227.1 - 0.31 10.7 1.4 0.41 10.3 0.2 1.8 2 0 0 2 2 2 0 Shigella flexneri OspC protein SesA PF17107.5 EGE01228.1 - 2.1e-27 95.7 0.0 3.2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EGE01228.1 - 1.6e-12 47.3 8.7 2.8e-12 46.6 8.7 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases SesA PF17107.5 EGE01229.1 - 8.6e-39 132.5 0.2 1.3e-38 132.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EGE01229.1 - 8e-12 45.1 10.9 8e-12 45.1 10.9 1.6 2 0 0 2 2 2 1 Sigma domain on NACHT-NTPases RhoGAP PF00620.27 EGE01232.1 - 1.7e-38 131.8 0.0 2.8e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Amidase PF01425.21 EGE01233.1 - 4e-73 246.9 0.2 4e-71 240.3 0.2 2.0 1 1 0 1 1 1 1 Amidase NAD_binding_5 PF07994.12 EGE01235.1 - 4.4e-145 483.1 0.1 5.3e-145 482.8 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGE01235.1 - 2.5e-45 153.2 0.6 6e-45 152.0 0.6 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PepSY PF03413.19 EGE01235.1 - 0.19 12.3 1.6 17 6.1 0.5 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribonucleas_3_3 PF14622.6 EGE01237.1 - 6.7e-07 29.5 0.0 9.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGE01237.1 - 0.00062 20.3 0.0 0.0042 17.7 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain Peptidase_S10 PF00450.22 EGE01239.1 - 1.1e-74 252.3 0.1 1.5e-74 251.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase LIM PF00412.22 EGE01241.1 - 1.2e-16 60.6 19.2 2.3e-11 43.8 3.2 3.3 3 1 0 3 3 3 2 LIM domain Glyco_hydro_3 PF00933.21 EGE01242.1 - 3.6e-55 187.6 0.0 4.3e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CitMHS PF03600.16 EGE01243.1 - 0.0098 15.1 4.4 0.026 13.7 4.4 1.6 1 1 0 1 1 1 1 Citrate transporter LapA_dom PF06305.11 EGE01243.1 - 0.013 15.3 2.9 2.2 8.2 0.2 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COesterase PF00135.28 EGE01244.1 - 5e-81 273.1 0.0 3.3e-71 240.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE01244.1 - 2.4e-11 43.9 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tim17 PF02466.19 EGE01247.1 - 9.9e-10 38.8 1.4 1.6e-09 38.1 1.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cu_amine_oxid PF01179.20 EGE01248.1 - 9.8e-167 555.0 0.3 1.2e-166 554.7 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGE01248.1 - 4.8e-05 23.7 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGE01248.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain p450 PF00067.22 EGE01250.1 - 5.8e-07 28.6 0.0 6.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EGE01253.1 - 1.7e-21 76.8 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE01253.1 - 6.5e-11 42.8 0.0 2.2e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE01253.1 - 5.5e-08 32.8 0.0 1.9e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE01253.1 - 1.7e-07 31.9 0.0 9e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE01253.1 - 1.9e-06 28.4 0.0 5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE01253.1 - 0.0017 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGE01253.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.19 EGE01253.1 - 0.023 14.8 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF1461 PF07314.11 EGE01253.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Ubie_methyltran PF01209.18 EGE01253.1 - 0.15 11.4 0.0 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGE01253.1 - 0.19 11.5 0.0 6 6.6 0.0 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UQ_con PF00179.26 EGE01254.1 - 1.5e-39 134.8 0.0 1.8e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE01254.1 - 0.019 14.7 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 EGE01254.1 - 0.058 13.0 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 HhH-GPD PF00730.25 EGE01255.1 - 1.3e-20 73.9 0.0 2.9e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGE01255.1 - 3.5e-07 29.7 0.0 1.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA_11 PF13086.6 EGE01256.1 - 5.1e-64 216.6 0.4 1.1e-63 215.5 0.4 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGE01256.1 - 3.6e-57 193.2 0.0 1.1e-56 191.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGE01256.1 - 1.4e-13 51.1 0.0 2.4e-12 47.0 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.6 EGE01256.1 - 7.6e-11 42.5 0.0 4.7e-10 40.0 0.0 2.4 3 1 0 3 3 1 1 AAA domain Viral_helicase1 PF01443.18 EGE01256.1 - 1.9e-09 37.6 0.1 0.072 12.8 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGE01256.1 - 1.9e-07 31.2 0.0 5.9e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGE01256.1 - 2.8e-07 30.1 0.2 2.7e-06 26.9 0.2 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGE01256.1 - 1.3e-05 25.5 0.1 0.00012 22.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.14 EGE01256.1 - 1.6e-05 24.3 0.0 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 EGE01256.1 - 3.7e-05 23.7 0.0 0.0045 16.8 0.0 3.2 2 1 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 EGE01256.1 - 0.00015 21.4 0.3 0.0014 18.2 0.4 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EGE01256.1 - 0.00018 21.9 0.1 0.00054 20.4 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGE01256.1 - 0.00021 20.4 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EGE01256.1 - 0.00042 19.8 0.0 0.013 15.0 0.0 2.8 2 1 0 2 2 1 1 PhoH-like protein Flavi_DEAD PF07652.14 EGE01256.1 - 0.0007 19.6 0.1 0.002 18.1 0.1 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 EGE01256.1 - 0.0023 16.9 0.0 0.005 15.8 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 EGE01256.1 - 0.0049 16.9 0.0 0.031 14.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) UvrD_C PF13361.6 EGE01256.1 - 0.011 15.2 0.5 4.3 6.6 0.0 3.0 2 2 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_24 PF13479.6 EGE01256.1 - 0.011 15.5 0.0 0.042 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGE01256.1 - 0.013 15.9 0.2 0.058 13.8 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGE01256.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.6 EGE01256.1 - 0.017 14.9 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain 4HB_MCP_1 PF12729.7 EGE01256.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CbiA PF01656.23 EGE01256.1 - 0.035 14.2 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TK PF00265.18 EGE01256.1 - 0.047 13.5 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase SRP54 PF00448.22 EGE01256.1 - 0.047 13.3 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGE01256.1 - 0.087 13.0 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EGE01256.1 - 0.11 12.4 0.1 0.75 9.7 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 EGE01256.1 - 0.11 12.9 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain CmcI PF04989.12 EGE01256.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 1 1 2 2 2 0 Cephalosporin hydroxylase Herpes_ori_bp PF02399.15 EGE01256.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Mg_chelatase PF01078.21 EGE01256.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGE01256.1 - 0.15 11.6 0.0 0.5 9.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGE01256.1 - 0.2 12.1 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.25 EGE01258.1 - 3.1e-34 118.5 0.0 3.6e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01258.1 - 1.4e-26 93.3 0.0 5.8e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01258.1 - 9.5e-05 21.3 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGE01258.1 - 0.00013 21.0 0.1 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGE01258.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE01258.1 - 0.04 13.2 0.2 1.4 8.1 0.2 2.6 1 1 1 2 2 2 0 Kinase-like PALP PF00291.25 EGE01259.1 - 4.1e-34 118.3 0.0 3.4e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 EGE01259.1 - 8.1e-10 39.2 0.0 4.5e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain MFS_1 PF07690.16 EGE01260.1 - 1.6e-46 158.9 40.0 2.2e-42 145.3 41.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily CPSF_A PF03178.15 EGE01261.1 - 4.7e-101 338.3 0.0 3.6e-100 335.4 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EGE01261.1 - 2.5e-14 52.8 0.0 4.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF5470 PF17564.2 EGE01262.1 - 0.026 14.7 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5470) AAA PF00004.29 EGE01263.1 - 3.8e-46 156.8 0.1 1.6e-41 141.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE01263.1 - 6e-10 38.8 0.0 2.5e-09 36.8 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EGE01263.1 - 8.8e-07 28.8 0.0 2.7e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EGE01263.1 - 1e-06 29.3 0.0 2.2e-05 24.9 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EGE01263.1 - 1.2e-05 25.5 0.0 3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 EGE01263.1 - 0.00033 20.6 0.0 0.00085 19.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 EGE01263.1 - 0.00084 19.3 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE01263.1 - 0.0034 17.7 0.3 0.083 13.2 0.3 3.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGE01263.1 - 0.0049 17.2 0.0 0.018 15.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 EGE01263.1 - 0.0089 16.2 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGE01263.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 EGE01263.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EGE01263.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGE01263.1 - 0.029 14.9 0.0 0.099 13.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EGE01263.1 - 0.035 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGE01263.1 - 0.044 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGE01263.1 - 0.07 13.7 0.0 0.27 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGE01263.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EGE01263.1 - 0.081 12.6 0.0 3.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 EGE01263.1 - 0.089 12.7 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 EGE01263.1 - 0.099 12.8 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EGE01263.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGE01263.1 - 0.17 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EGE01263.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGE01263.1 - 0.86 9.3 0.0 0.86 9.3 0.0 3.7 3 0 0 3 3 1 0 AAA domain Sec66 PF09802.9 EGE01264.1 - 9.8e-79 263.1 0.7 1.2e-78 262.8 0.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EGE01264.1 - 0.00017 21.6 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) DUF1539 PF07560.11 EGE01264.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF2465 PF10239.9 EGE01264.1 - 0.027 13.7 0.1 0.04 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) ORC3_N PF07034.11 EGE01265.1 - 1.3e-36 126.4 0.0 5.9e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGE01265.1 - 3.7e-24 85.4 0.5 1.2e-15 57.8 0.0 2.8 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal DUF3456 PF11938.8 EGE01265.1 - 0.039 14.5 0.1 0.089 13.3 0.1 1.6 1 0 0 1 1 1 0 TLR4 regulator and MIR-interacting MSAP Symplekin_C PF12295.8 EGE01265.1 - 0.054 13.6 0.1 0.33 11.0 0.0 2.3 3 0 0 3 3 3 0 Symplekin tight junction protein C terminal PPR_2 PF13041.6 EGE01266.1 - 2.8e-09 37.0 0.0 0.38 11.0 0.0 5.7 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.20 EGE01266.1 - 0.0032 17.6 0.6 6.5 7.2 0.0 5.0 6 0 0 6 6 6 1 PPR repeat PPR_3 PF13812.6 EGE01266.1 - 0.0045 17.0 0.1 1 9.5 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain HEAT_2 PF13646.6 EGE01267.1 - 0.017 15.5 0.5 0.037 14.4 0.5 1.6 1 0 0 1 1 1 0 HEAT repeats Nop14 PF04147.12 EGE01268.1 - 9.2e-290 963.8 24.5 1.1e-289 963.5 24.5 1.1 1 0 0 1 1 1 1 Nop14-like family Cylicin_N PF15241.6 EGE01268.1 - 6.8 6.9 9.4 1.2 9.3 0.5 3.2 3 0 0 3 3 3 0 Cylicin N-terminus COesterase PF00135.28 EGE01269.1 - 3e-89 300.2 0.0 3.6e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE01269.1 - 2.4e-06 27.6 0.0 6.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE01269.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGE01269.1 - 0.0012 19.5 0.0 0.0036 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 EGE01269.1 - 0.05 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SmpA_OmlA PF04355.13 EGE01269.1 - 0.058 13.2 0.3 11 5.9 0.0 2.6 2 0 0 2 2 2 0 SmpA / OmlA family Abhydrolase_4 PF08386.10 EGE01271.1 - 0.08 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Peptidase_M6 PF05547.11 EGE01273.1 - 4.1e-06 25.5 1.2 0.00028 19.4 0.5 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 RabGAP-TBC PF00566.18 EGE01274.1 - 4e-42 144.3 0.0 2.4e-40 138.5 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3322 PF11795.8 EGE01274.1 - 0.24 11.4 2.2 0.23 11.4 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Pkinase PF00069.25 EGE01275.1 - 1.4e-17 63.9 0.0 2.3e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EGE01275.1 - 2.5e-08 34.4 9.2 3.2e-05 24.6 0.0 5.5 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.22 EGE01275.1 - 8.8e-08 31.8 10.4 0.25 11.7 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat Pkinase_Tyr PF07714.17 EGE01275.1 - 0.00031 20.1 0.0 0.00056 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 EGE01275.1 - 0.0028 18.1 0.1 0.26 11.9 0.1 3.4 3 0 0 3 3 3 1 HEAT-like repeat Ge1_WD40 PF16529.5 EGE01275.1 - 0.017 14.1 0.0 0.35 9.8 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tti2 PF10521.9 EGE01275.1 - 0.053 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Tti2 family zf-C2H2 PF00096.26 EGE01277.1 - 5.5e-06 26.6 35.5 0.00073 19.9 4.5 4.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE01277.1 - 0.00022 21.8 31.7 0.003 18.3 2.5 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGE01277.1 - 0.0025 17.5 14.8 0.12 12.2 0.4 3.6 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EGE01277.1 - 0.0033 17.8 18.1 0.2 12.1 0.3 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGE01277.1 - 0.046 13.7 12.8 0.076 13.0 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger CpXC PF14353.6 EGE01277.1 - 0.066 13.3 6.5 1.2 9.1 0.4 2.3 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 EGE01277.1 - 0.11 12.6 9.6 1 9.5 2.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.12 EGE01277.1 - 0.93 9.5 7.3 0.64 10.0 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-C2H2_8 PF15909.5 EGE01277.1 - 1.1 9.5 12.1 0.72 10.2 7.5 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon Rubredoxin_2 PF18073.1 EGE01277.1 - 2.1 8.1 8.1 8.6 6.2 1.2 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain NUDIX PF00293.28 EGE01278.1 - 3.9e-27 94.9 0.0 1.8e-26 92.7 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF202 PF02656.15 EGE01279.1 - 6.7e-16 58.5 4.8 1e-15 57.9 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 EGE01279.1 - 0.34 11.1 1.7 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV MatE PF01554.18 EGE01280.1 - 2.6e-28 98.7 29.6 7.6e-22 77.7 12.8 3.4 4 0 0 4 4 4 3 MatE Otopetrin PF03189.13 EGE01280.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.4 1 1 0 1 1 1 0 Otopetrin FAM27 PF15832.5 EGE01280.1 - 0.057 14.0 0.2 0.13 12.9 0.2 1.5 1 0 0 1 1 1 0 FAM27 D and E protein family DUF4696 PF15767.5 EGE01280.1 - 0.093 11.3 1.8 0.13 10.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4696) DnaJ PF00226.31 EGE01281.1 - 1.7e-14 53.7 1.3 5.8e-14 52.0 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain Afi1 PF07792.12 EGE01281.1 - 10 6.6 6.5 1.8 9.1 2.8 1.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DEAD PF00270.29 EGE01282.1 - 2.6e-33 115.2 0.0 5.3e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE01282.1 - 3.9e-24 85.1 0.0 1.7e-23 83.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGE01282.1 - 2.4e-21 75.7 0.0 7.3e-21 74.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGE01282.1 - 3.1e-05 24.0 0.0 9.7e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGE01282.1 - 0.0087 16.2 0.0 0.057 13.6 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain ssDNA-exonuc_C PF10141.9 EGE01282.1 - 3.1 7.4 6.0 0.49 10.0 0.2 2.5 3 0 0 3 3 3 0 Single-strand DNA-specific exonuclease, C terminal domain AA_permease PF00324.21 EGE01283.1 - 1.1e-34 119.9 23.3 1.8e-27 96.1 13.4 2.0 2 0 0 2 2 2 2 Amino acid permease FtsX PF02687.21 EGE01283.1 - 1.3 9.5 10.7 1.9 9.0 8.1 2.2 2 0 0 2 2 2 0 FtsX-like permease family Zn_clus PF00172.18 EGE01284.1 - 0.0003 20.8 10.5 0.00054 20.0 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 EGE01286.1 - 3.8e-47 160.3 0.0 9.1e-47 159.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE01286.1 - 6.5e-25 87.6 0.1 2.7e-24 85.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGE01286.1 - 9.7e-20 70.6 1.7 4e-19 68.6 1.7 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain RPA_C PF08784.11 EGE01287.1 - 1.4e-13 51.4 0.2 5.8e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EGE01287.1 - 0.00069 19.5 0.0 0.0035 17.3 0.0 2.1 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.19 EGE01288.1 - 5.5e-29 101.4 0.0 4.1e-27 95.3 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3678 PF12435.8 EGE01288.1 - 2.2 7.7 10.0 9.8 5.6 9.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) RRM_1 PF00076.22 EGE01289.1 - 4.9e-19 67.9 0.1 9.6e-11 41.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 EGE01290.1 - 3.9e-64 216.2 0.0 6.1e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGE01290.1 - 1.8e-31 109.3 0.2 3.6e-31 108.3 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGE01290.1 - 1.3e-21 77.2 0.0 1.3e-20 74.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGE01290.1 - 0.083 13.1 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Flavodoxin domain MOR2-PAG1_N PF14222.6 EGE01291.1 - 3.9e-210 699.5 0.0 5.9e-210 698.9 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EGE01291.1 - 9.3e-88 294.3 0.4 3e-87 292.7 0.0 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EGE01291.1 - 5.3e-28 97.2 10.1 1.4e-14 52.8 1.0 5.1 3 1 1 4 4 4 4 Cell morphogenesis central region Git3 PF11710.8 EGE01292.1 - 8.9e-24 84.4 17.9 2.3e-23 83.1 17.9 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGE01292.1 - 2.4e-10 40.4 0.7 2.4e-10 40.4 0.7 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EGE01292.1 - 0.3 10.2 17.2 0.048 12.8 13.1 1.6 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor DENN PF02141.21 EGE01293.1 - 1.1e-37 129.8 0.0 2.1e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGE01293.1 - 2.8e-06 28.0 0.1 1.3e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EGE01293.1 - 0.047 14.2 7.3 0.041 14.4 5.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A TMF_TATA_bd PF12325.8 EGE01293.1 - 2.3 8.5 17.5 0.46 10.7 3.8 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 EGE01293.1 - 2.8 8.2 14.2 0.24 11.6 3.8 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-HIT PF04438.16 EGE01294.1 - 7.4e-10 38.5 10.9 1.3e-09 37.7 10.9 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF5555 PF17710.1 EGE01294.1 - 0.083 12.4 1.7 0.51 9.8 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5555) zf-MYND PF01753.18 EGE01294.1 - 3 8.0 12.6 6.5 6.9 12.6 1.6 1 0 0 1 1 1 0 MYND finger adh_short_C2 PF13561.6 EGE01295.1 - 1.9e-54 184.7 0.4 2.3e-54 184.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE01295.1 - 5.6e-47 159.7 0.4 7.1e-47 159.4 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE01295.1 - 2.4e-10 40.6 0.3 6.1e-10 39.3 0.3 1.6 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGE01295.1 - 0.0027 18.0 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1542 PF07564.11 EGE01296.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Sulfotransfer_3 PF13469.6 EGE01296.1 - 0.15 12.4 0.1 1.4 9.3 0.1 2.1 1 1 0 1 1 1 0 Sulfotransferase family Sulfotransfer_3 PF13469.6 EGE01297.1 - 0.0091 16.4 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 2 Sulfotransferase family DUF1664 PF07889.12 EGE01298.1 - 0.0033 17.5 2.8 0.53 10.3 1.2 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 EGE01298.1 - 0.0093 14.9 1.1 0.014 14.3 1.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ADIP PF11559.8 EGE01298.1 - 0.01 16.0 2.4 0.13 12.4 2.1 2.3 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding CCDC144C PF14915.6 EGE01298.1 - 0.01 15.0 0.2 0.022 13.9 0.1 1.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region WEMBL PF05701.11 EGE01298.1 - 0.016 13.9 0.3 0.026 13.2 0.3 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Fez1 PF06818.15 EGE01298.1 - 0.035 14.6 1.7 0.16 12.4 0.1 2.2 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 EGE01298.1 - 0.046 13.8 0.1 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG5 PF10392.9 EGE01298.1 - 0.062 13.5 1.2 0.4 10.9 1.2 2.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 EGE01298.1 - 0.067 13.2 0.2 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 EGE01298.1 - 0.069 13.5 1.0 0.13 12.7 0.2 1.8 2 0 0 2 2 2 0 YlqD protein LPP PF04728.13 EGE01298.1 - 0.071 13.5 6.1 1.6 9.2 0.2 3.8 3 1 1 4 4 3 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 EGE01298.1 - 0.096 12.7 0.8 0.44 10.6 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 EGE01298.1 - 0.12 12.8 0.9 1.7 9.0 0.2 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 EGE01298.1 - 0.21 12.1 2.1 46 4.6 0.0 3.4 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 EGE01298.1 - 1.1 9.7 3.9 1.3 9.4 1.8 2.2 1 1 1 2 2 2 0 Syntaxin-like protein TolA_bind_tri PF16331.5 EGE01298.1 - 5.8 7.1 6.1 16 5.7 0.3 3.0 2 1 1 3 3 3 0 TolA binding protein trimerisation Peptidase_C48 PF02902.19 EGE01301.1 - 5e-26 91.9 0.0 7.5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PAP2 PF01569.21 EGE01302.1 - 1.2e-17 64.0 2.4 1.2e-17 64.0 2.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGE01302.1 - 0.099 12.3 10.1 0.55 9.9 10.1 2.3 1 1 0 1 1 1 0 PAP2 superfamily Ras PF00071.22 EGE01303.1 - 2e-47 160.8 0.0 2.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE01303.1 - 5.6e-20 71.7 0.0 1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE01303.1 - 0.00016 21.1 0.0 0.00026 20.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGE01303.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGE01303.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DASH_Dad1 PF08649.10 EGE01304.1 - 9.3e-23 80.2 2.4 1.2e-22 79.9 2.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EGE01304.1 - 0.041 13.8 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 PI3K_1B_p101 PF10486.9 EGE01306.1 - 0.88 7.3 7.7 0.99 7.1 7.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PRP38_assoc PF12871.7 EGE01306.1 - 5.5 7.7 17.7 12 6.5 17.7 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term LSM PF01423.22 EGE01308.1 - 4e-20 71.3 0.3 4.6e-20 71.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain SH2_2 PF14633.6 EGE01308.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 SH2 domain DUF866 PF05907.13 EGE01309.1 - 1.1e-63 213.8 0.7 1.2e-63 213.6 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 EGE01309.1 - 0.12 12.7 0.3 0.12 12.7 0.3 2.2 2 1 1 3 3 3 0 Probable Zinc-ribbon domain HalOD2 PF18547.1 EGE01309.1 - 0.15 12.0 4.3 1.5 8.8 4.4 2.2 1 1 1 2 2 2 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 EGE01309.1 - 0.17 11.8 2.5 10 6.2 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain FAD_binding_3 PF01494.19 EGE01310.1 - 1.3e-70 238.4 0.0 1.6e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGE01310.1 - 2.2e-35 122.1 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EGE01310.1 - 0.00019 21.1 0.0 0.024 14.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE01310.1 - 0.015 14.5 0.0 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE01310.1 - 0.04 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE01310.1 - 0.091 13.3 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EGE01310.1 - 0.14 11.8 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DDHD PF02862.17 EGE01312.1 - 2.6e-26 93.1 0.0 1e-23 84.7 0.0 2.8 2 1 0 2 2 2 1 DDHD domain CENP-U PF13097.6 EGE01312.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit MoCF_biosynth PF00994.24 EGE01313.1 - 2.1e-48 163.7 0.1 6.7e-23 81.0 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGE01313.1 - 2.4e-38 131.4 2.7 3.9e-38 130.7 2.7 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGE01313.1 - 1.5e-18 66.8 0.1 3.4e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) ATP-synt_C PF00137.21 EGE01314.1 - 1.5e-25 89.3 28.7 1.8e-16 60.2 10.8 2.5 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EGE01314.1 - 0.57 9.5 5.1 0.12 11.7 0.7 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Ras PF00071.22 EGE01315.1 - 6.8e-49 165.6 0.2 9e-49 165.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE01315.1 - 5.1e-27 94.5 0.4 1.4e-26 93.0 0.4 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE01315.1 - 2.8e-15 56.2 0.2 3.4e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGE01315.1 - 2.6e-05 24.2 0.5 0.024 14.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGE01315.1 - 3.3e-05 23.5 0.2 0.00017 21.2 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGE01315.1 - 0.00014 21.9 0.3 0.00068 19.7 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGE01315.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGE01315.1 - 0.0036 16.7 0.2 0.0065 15.9 0.2 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 EGE01315.1 - 0.2 11.9 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Kei1 PF08552.11 EGE01316.1 - 2.7e-60 203.5 0.1 3.7e-60 203.1 0.1 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.22 EGE01317.1 - 1.4e-53 180.7 0.0 3e-46 156.8 0.0 2.7 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EGE01317.1 - 1.1e-28 98.9 0.0 9.7e-14 51.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EGE01317.1 - 3.5e-28 98.6 0.0 7.2e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EGE01317.1 - 2.2e-05 24.3 0.9 6.4e-05 22.8 0.1 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF3431 PF11913.8 EGE01318.1 - 2.8e-88 295.3 1.4 3.4e-88 295.0 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) EXS PF03124.14 EGE01319.1 - 2.2e-103 346.1 10.8 2.5e-103 345.9 10.8 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 EGE01320.1 - 2.9e-43 148.1 3.7 3.7e-43 147.7 3.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EGE01320.1 - 2.6e-11 43.2 10.0 4.2e-11 42.5 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE01320.1 - 6.7e-11 42.4 10.4 1e-10 41.8 10.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGE01320.1 - 1.4e-10 40.9 7.6 2.2e-10 40.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE01320.1 - 2.4e-10 40.1 5.8 3.5e-10 39.6 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE01320.1 - 4.8e-08 32.9 9.3 9.7e-08 31.9 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGE01320.1 - 4.7e-07 29.6 7.2 7.6e-07 28.9 7.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGE01320.1 - 5.6e-07 29.4 6.6 8.8e-07 28.8 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGE01320.1 - 6.1e-07 29.6 7.2 1.2e-06 28.7 7.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGE01320.1 - 4.6e-06 26.7 9.4 7.9e-06 25.9 9.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGE01320.1 - 0.0016 18.5 5.4 0.0029 17.7 5.4 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGE01320.1 - 0.0076 16.3 3.0 0.013 15.5 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGE01320.1 - 0.01 15.7 3.5 0.019 14.8 3.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 EGE01320.1 - 0.022 14.5 4.9 0.042 13.7 4.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EGE01320.1 - 0.16 11.8 7.6 0.32 10.8 7.6 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 EGE01320.1 - 0.23 10.8 0.9 0.47 9.8 0.9 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 EGE01320.1 - 0.34 10.7 4.1 0.9 9.3 4.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGE01320.1 - 0.47 10.1 4.7 0.84 9.3 4.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EGE01320.1 - 0.51 10.6 4.4 1.2 9.4 4.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain C2 PF00168.30 EGE01321.1 - 3.7e-10 40.0 0.0 6.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.23 EGE01322.1 - 5.2e-52 176.7 0.1 1.9e-50 171.6 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE01322.1 - 5.3e-16 59.0 0.1 3.7e-15 56.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EGE01322.1 - 6.6e-05 22.7 11.5 6.6e-05 22.7 11.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EGE01322.1 - 0.00041 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 EGE01322.1 - 2.3 8.6 26.5 0.024 14.9 11.7 2.6 2 0 0 2 2 2 0 Ring finger domain Hamartin PF04388.12 EGE01322.1 - 2.6 6.6 23.5 3.9 6.0 23.5 1.2 1 0 0 1 1 1 0 Hamartin protein LRR_4 PF12799.7 EGE01323.1 - 4.8e-06 26.8 4.6 0.61 10.6 0.0 6.8 6 3 3 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGE01323.1 - 0.032 14.0 1.0 21 4.9 0.0 5.1 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 EGE01323.1 - 0.054 13.6 10.9 16 5.8 0.0 6.4 8 0 0 8 8 8 0 Leucine Rich repeat BSP_II PF05432.11 EGE01323.1 - 0.16 11.6 10.8 0.24 11.0 10.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Mt_ATP-synt_B PF05405.14 EGE01323.1 - 1 8.9 11.4 1.8 8.2 11.4 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CDC45 PF02724.14 EGE01323.1 - 1.6 6.9 10.3 2.4 6.3 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.13 EGE01323.1 - 2.6 7.0 15.0 3.3 6.6 15.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dicty_REP PF05086.12 EGE01324.1 - 0.65 7.9 3.2 0.74 7.7 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 EGE01324.1 - 1.1 7.4 14.9 1.3 7.2 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EGE01324.1 - 1.8 7.9 20.9 2 7.7 20.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 EGE01324.1 - 4.3 7.1 8.7 5.5 6.7 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MCM_bind PF09739.9 EGE01324.1 - 9.7 4.5 9.1 11 4.3 9.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HRCT1 PF15758.5 EGE01325.1 - 0.028 15.4 5.3 5.5 8.0 0.1 2.6 2 0 0 2 2 2 0 Histidine-rich carboxyl terminus protein 1 Gar1 PF04410.14 EGE01325.1 - 0.76 9.5 4.6 1.5 8.6 4.6 1.4 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region NMO PF03060.15 EGE01326.1 - 2.3e-31 109.4 3.9 1e-25 90.9 1.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGE01326.1 - 5e-08 32.4 1.9 8.2e-08 31.7 1.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EGE01326.1 - 0.00043 19.5 1.4 0.0006 19.1 1.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EGE01326.1 - 0.0014 17.7 5.3 0.029 13.4 2.6 2.5 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain RNA_pol_L_2 PF13656.6 EGE01327.1 - 3.9e-26 90.6 0.0 6.6e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGE01327.1 - 5.6e-10 38.5 0.0 8.9e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SIR2_2 PF13289.6 EGE01327.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain EF-hand_4 PF12763.7 EGE01328.1 - 2e-24 85.5 0.0 1.6e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EGE01328.1 - 3.8e-10 39.2 0.2 3.8e-10 39.2 0.2 2.2 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 EGE01328.1 - 6.9e-06 26.4 62.1 2.1e-05 24.9 33.2 7.0 4 3 2 6 6 6 2 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EGE01328.1 - 0.0002 20.7 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGE01328.1 - 0.00069 20.0 2.7 0.14 12.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGE01328.1 - 0.13 12.2 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair Na_Ca_ex PF01699.24 EGE01329.1 - 1.8e-49 167.6 42.1 5.8e-27 94.5 16.7 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SPC12 PF06645.13 EGE01329.1 - 0.21 11.7 2.1 0.92 9.6 0.3 3.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cnd2 PF05786.14 EGE01330.1 - 0 1027.3 7.0 0 1027.1 7.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGE01330.1 - 0.02 15.1 2.3 0.02 15.1 0.0 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ribosomal_60s PF00428.19 EGE01330.1 - 4.5 7.9 8.8 2.4 8.8 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein MARVEL PF01284.23 EGE01331.1 - 0.024 14.7 0.5 0.024 14.7 0.5 1.9 2 0 0 2 2 2 0 Membrane-associating domain ECF_trnsprt PF12822.7 EGE01331.1 - 0.04 14.0 0.5 0.065 13.3 0.5 1.4 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF1461 PF07314.11 EGE01331.1 - 3.6 7.4 6.0 21 5.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) FeoB_associated PF12669.7 EGE01331.1 - 4.7 7.7 5.2 14 6.1 0.8 2.7 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein MFS_1 PF07690.16 EGE01333.1 - 2.9e-29 102.1 29.7 4.2e-29 101.6 29.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ADK PF00406.22 EGE01334.1 - 7.1e-41 139.8 0.1 2e-40 138.4 0.1 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGE01334.1 - 5.2e-35 120.8 0.0 8.4e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGE01334.1 - 1e-08 35.8 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE01334.1 - 6e-05 23.2 0.0 0.00058 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGE01334.1 - 0.005 16.5 0.1 0.04 13.6 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 EGE01334.1 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ribosomal_S14 PF00253.21 EGE01335.1 - 8.8e-14 51.0 4.5 9.9e-14 50.9 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PCI PF01399.27 EGE01336.1 - 4.2e-11 43.3 0.1 1.4e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EGE01336.1 - 2e-10 40.2 3.6 3.9e-10 39.3 3.6 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DUF2408 PF10303.9 EGE01336.1 - 0.058 14.0 2.8 0.35 11.4 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF3631 PF12307.8 EGE01336.1 - 0.28 11.4 2.7 15 5.8 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3631) DUF883 PF05957.13 EGE01336.1 - 0.32 11.6 9.6 1.7 9.3 4.5 3.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) 4HBT PF03061.22 EGE01338.1 - 3.2e-05 24.2 0.0 4.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 EGE01338.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain 4HBT_3 PF13622.6 EGE01339.1 - 1.2e-47 163.2 0.0 1.4e-47 163.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_20 PF00982.21 EGE01341.1 - 1.3e-157 525.3 0.1 2.3e-157 524.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGE01341.1 - 5.4e-35 120.6 0.0 2.6e-34 118.4 0.0 2.0 1 1 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EGE01341.1 - 0.021 14.5 0.9 0.076 12.7 0.4 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EGE01341.1 - 0.098 13.1 0.0 0.36 11.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Sporozoite_P67 PF05642.11 EGE01341.1 - 9.3 4.2 9.0 16 3.4 9.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Stk19 PF10494.9 EGE01342.1 - 1.4e-84 283.6 0.0 1.8e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.8 EGE01343.1 - 7.5e-13 48.9 0.1 9.1e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) GUN4_N PF16416.5 EGE01343.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal zf-H2C2_2 PF13465.6 EGE01344.1 - 3.6e-10 39.8 16.2 9.3e-05 22.7 1.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGE01344.1 - 2.6e-07 30.7 23.9 0.023 15.1 7.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE01344.1 - 0.00022 21.8 20.9 0.15 13.0 5.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EGE01344.1 - 0.014 15.7 6.3 0.025 14.9 6.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EGE01344.1 - 0.018 15.0 19.2 0.13 12.3 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EGE01344.1 - 0.071 13.0 0.4 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EGE01344.1 - 0.15 12.4 7.4 1.7 9.0 2.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EGE01344.1 - 0.18 11.6 6.9 3.8 7.4 1.6 3.1 1 1 1 2 2 2 0 GAGA factor DUF3268 PF11672.8 EGE01344.1 - 0.26 11.6 1.1 0.46 10.8 1.1 1.4 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2HE PF16278.5 EGE01344.1 - 0.33 11.4 15.1 0.42 11.1 1.1 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DZR PF12773.7 EGE01344.1 - 0.74 9.9 6.5 6.6 6.8 6.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_9 PF16293.5 EGE01344.1 - 1.8 8.5 4.6 2.4 8.1 0.2 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-BED PF02892.15 EGE01344.1 - 1.9 8.5 9.8 5.7 7.0 5.4 2.7 1 1 1 2 2 2 0 BED zinc finger zf_C2H2_ZHX PF18387.1 EGE01344.1 - 3.3 7.4 8.5 8.7 6.1 0.0 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EGE01344.1 - 3.8 7.9 10.9 2.6 8.4 1.3 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) Allexi_40kDa PF05549.11 EGE01346.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.9 3 0 0 3 3 3 0 Allexivirus 40kDa protein SET PF00856.28 EGE01348.1 - 3e-08 34.2 0.1 1e-06 29.3 0.0 3.1 2 1 1 3 3 3 2 SET domain TPR_16 PF13432.6 EGE01348.1 - 0.033 14.8 0.2 0.096 13.4 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SAP PF02037.27 EGE01348.1 - 0.037 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain LolB PF03550.14 EGE01348.1 - 0.064 13.3 0.1 0.19 11.8 0.1 1.8 1 1 0 1 1 1 0 Outer membrane lipoprotein LolB TPR_9 PF13371.6 EGE01348.1 - 0.089 13.0 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat SWIM PF04434.17 EGE01350.1 - 2.6e-05 23.8 0.2 4.6e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger Nop14 PF04147.12 EGE01350.1 - 9.3 4.3 7.9 15 3.6 7.9 1.2 1 0 0 1 1 1 0 Nop14-like family ADH_N PF08240.12 EGE01351.1 - 2.7e-24 85.2 0.2 5.8e-24 84.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE01351.1 - 3e-24 85.5 0.2 4.4e-24 84.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE01351.1 - 7.8e-05 23.7 0.0 0.00013 23.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGE01351.1 - 0.059 12.8 0.2 0.15 11.5 0.2 1.6 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus v110 PF01639.17 EGE01351.1 - 0.064 13.1 0.6 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Viral family 110 Methyltransf_32 PF13679.6 EGE01351.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Peripla_BP_6 PF13458.6 EGE01351.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein RhoGAP PF00620.27 EGE01352.1 - 7.7e-14 51.8 0.2 3.3e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EGE01352.1 - 6.6e-11 42.3 0.2 6.6e-10 39.1 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 EGE01352.1 - 1.7e-09 37.6 0.0 3.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YojJ PF10372.9 EGE01352.1 - 0.035 14.2 1.3 0.24 11.5 0.5 2.7 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus RTA1 PF04479.13 EGE01353.1 - 5.9e-33 114.2 2.4 8.2e-33 113.8 2.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Asp-Al_Ex PF06826.12 EGE01353.1 - 0.054 13.3 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Predicted Permease Membrane Region AAA PF00004.29 EGE01354.1 - 2.5e-14 53.8 0.0 6.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGE01354.1 - 8.5e-14 52.0 0.1 5.3e-13 49.4 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EGE01354.1 - 1.3e-12 48.5 0.4 2.6e-11 44.2 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 EGE01354.1 - 3.8e-08 33.2 0.0 9.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 EGE01354.1 - 2.1e-06 27.3 0.0 4.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein NTPase_1 PF03266.15 EGE01354.1 - 0.00035 20.5 0.0 0.00061 19.7 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_7 PF12775.7 EGE01354.1 - 0.00044 19.8 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGE01354.1 - 0.00063 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 EGE01354.1 - 0.00067 20.0 0.0 0.0018 18.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EGE01354.1 - 0.0013 18.8 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_30 PF13604.6 EGE01354.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGE01354.1 - 0.0019 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 EGE01354.1 - 0.002 18.1 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EGE01354.1 - 0.0026 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.14 EGE01354.1 - 0.0037 16.5 0.0 0.0062 15.8 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ABC_tran PF00005.27 EGE01354.1 - 0.0049 17.4 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 EGE01354.1 - 0.0058 16.6 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EGE01354.1 - 0.0072 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain RNA12 PF10443.9 EGE01354.1 - 0.0093 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein RNA_helicase PF00910.22 EGE01354.1 - 0.01 16.2 0.1 0.029 14.8 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.6 EGE01354.1 - 0.013 16.1 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGE01354.1 - 0.017 14.9 0.0 0.047 13.4 0.0 1.7 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGE01354.1 - 0.018 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGE01354.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGE01354.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EGE01354.1 - 0.059 13.6 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGE01354.1 - 0.078 13.0 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGE01354.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGE01354.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 EGE01354.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EGE01354.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Herpes_US12 PF05363.12 EGE01354.1 - 1.2 9.9 4.9 24 5.8 0.1 3.5 3 0 0 3 3 3 0 Herpesvirus US12 family Thioredoxin_7 PF13899.6 EGE01355.1 - 3.6e-15 55.9 0.0 7.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EGE01355.1 - 1.2e-13 50.7 0.1 2.1e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGE01355.1 - 3.7e-07 30.2 0.0 1.3e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredoxin_2 PF13098.6 EGE01355.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1299 PF06975.11 EGE01355.1 - 0.11 12.6 0.3 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) Pkinase PF00069.25 EGE01357.1 - 5.9e-69 232.4 0.0 8.1e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01357.1 - 1.6e-50 171.8 0.0 2.4e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01357.1 - 4.4e-06 25.7 0.8 4.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGE01357.1 - 0.027 13.8 0.0 0.45 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like COesterase PF00135.28 EGE01358.1 - 8.8e-55 186.5 0.0 2.7e-54 184.9 0.0 1.6 1 1 1 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE01358.1 - 6.1e-09 36.0 0.1 5e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE01358.1 - 0.017 14.6 0.0 0.049 13.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 EGE01359.1 - 8.3e-24 84.0 0.0 1.2e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01359.1 - 5.5e-08 32.8 12.1 9.9e-08 32.0 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EGE01359.1 - 0.1 12.2 0.4 0.35 10.5 0.4 1.9 1 0 0 1 1 1 0 Trimerisation motif MR_MLE_C PF13378.6 EGE01360.1 - 1e-41 142.9 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGE01360.1 - 1.3e-09 38.3 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Beta-lactamase PF00144.24 EGE01361.1 - 2.7e-23 82.7 0.0 4.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase adh_short_C2 PF13561.6 EGE01362.1 - 2e-52 178.1 0.0 5.3e-52 176.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE01362.1 - 8.6e-39 133.0 0.1 3.7e-38 130.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE01362.1 - 3e-05 24.0 0.2 5.3e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF3431 PF11913.8 EGE01363.1 - 2.6e-84 282.3 0.1 3.3e-84 282.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlxA PF14282.6 EGE01363.1 - 0.015 15.3 1.5 0.03 14.3 1.5 1.4 1 0 0 1 1 1 0 FlxA-like protein Mucin2_WxxW PF13330.6 EGE01364.1 - 0.031 15.1 0.0 0.071 13.9 0.0 1.6 1 0 0 1 1 1 0 Mucin-2 protein WxxW repeating region ox_reductase_C PF08635.10 EGE01366.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Amidohydro_2 PF04909.14 EGE01367.1 - 2.6e-19 70.1 0.0 2.4e-18 66.9 0.0 1.9 1 1 1 2 2 2 1 Amidohydrolase APH PF01636.23 EGE01368.1 - 3.9e-11 43.3 0.0 1.6e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE01368.1 - 3.7e-05 22.8 0.1 0.29 9.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 EGE01368.1 - 0.0081 15.4 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase AA_permease PF00324.21 EGE01369.1 - 1.1e-141 472.7 36.2 1.4e-141 472.4 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE01369.1 - 4e-34 118.2 37.0 5.5e-34 117.7 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 EGE01371.1 - 1e-27 97.0 0.3 1.4e-27 96.5 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01371.1 - 1.8e-08 34.4 10.0 3.3e-08 33.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 EGE01373.1 - 4.6e-37 125.9 3.3 2.6e-07 31.1 0.8 7.8 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EGE01373.1 - 7e-28 95.8 6.0 5.6e-08 32.9 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.7 EGE01373.1 - 2.1e-26 92.3 0.2 1.3e-11 44.9 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE01373.1 - 1.5e-24 83.4 1.1 0.00012 22.2 0.1 9.0 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EGE01373.1 - 2.8e-23 81.6 5.6 3.2e-07 30.5 0.1 6.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Asp_protease_2 PF13650.6 EGE01373.1 - 0.077 13.6 0.1 7.1 7.3 0.0 3.3 3 1 1 4 4 4 0 Aspartyl protease Glyoxalase_6 PF18029.1 EGE01373.1 - 0.17 12.7 0.3 1.3 9.9 0.0 2.3 2 1 0 2 2 2 0 Glyoxalase-like domain LSM PF01423.22 EGE01374.1 - 1.5e-21 75.8 0.1 1.7e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE01374.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain ArfGap PF01412.18 EGE01377.1 - 2.2e-32 111.6 0.0 2.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EGE01377.1 - 1.2e-17 64.5 8.5 1.9e-17 63.8 8.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGE01377.1 - 1.4e-11 44.8 0.5 4.1e-11 43.3 0.2 2.0 2 0 0 2 2 2 1 PH domain Chorion_2 PF03964.15 EGE01378.1 - 0.024 15.5 5.4 0.024 15.5 5.4 2.5 2 1 0 2 2 2 0 Chorion family 2 Pkinase PF00069.25 EGE01379.1 - 1.3e-22 80.4 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01379.1 - 3.5e-05 23.2 0.0 6.1e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE01379.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGE01379.1 - 0.025 13.5 0.3 0.036 13.1 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PI3_PI4_kinase PF00454.27 EGE01380.1 - 1.8e-35 123.0 0.0 3.2e-33 115.6 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGE01380.1 - 1.6e-24 86.3 0.0 3.8e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGE01380.1 - 0.072 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase PF00069.25 EGE01381.1 - 9.4e-73 244.8 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01381.1 - 8.1e-35 120.3 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGE01381.1 - 4.5e-16 59.0 0.2 1.1e-15 57.7 0.2 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGE01381.1 - 4e-08 32.9 0.0 4.2e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGE01381.1 - 2.5e-06 26.6 0.0 3.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EGE01381.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGE01381.1 - 0.0043 16.4 0.1 0.0071 15.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGE01381.1 - 0.033 13.1 0.3 0.051 12.5 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGE01381.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 EGE01382.1 - 1.5e-70 238.2 0.0 2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.17 EGE01382.1 - 0.074 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 K-box region DUF3045 PF11243.8 EGE01382.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) IGR PF09597.10 EGE01383.1 - 4.5e-07 29.9 0.1 8.6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.25 EGE01384.1 - 2e-62 211.0 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01384.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE01384.1 - 0.097 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGE01384.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE01384.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Syja_N PF02383.18 EGE01385.1 - 2.2e-73 247.4 0.0 3.2e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGE01385.1 - 7.1e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FCH PF00611.23 EGE01386.1 - 0.00054 20.2 3.0 0.00054 20.2 3.0 1.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_GP20 PF06810.11 EGE01386.1 - 0.11 12.3 6.2 0.16 11.8 6.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Use1 PF09753.9 EGE01386.1 - 0.33 10.6 12.7 0.36 10.5 12.7 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Macoilin PF09726.9 EGE01386.1 - 0.45 9.0 11.1 0.48 8.9 11.1 1.0 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 EGE01386.1 - 1.3 9.2 9.2 1.9 8.6 9.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5446 PF17522.2 EGE01386.1 - 6.5 7.0 8.7 4 7.7 0.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5446) G-patch PF01585.23 EGE01387.1 - 0.00038 20.3 0.1 0.0068 16.3 0.1 2.6 1 1 0 1 1 1 1 G-patch domain Tim54 PF11711.8 EGE01387.1 - 0.0033 16.3 6.8 0.005 15.7 6.8 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EGE01387.1 - 0.094 13.1 5.0 0.2 12.1 5.0 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3682 PF12446.8 EGE01387.1 - 0.22 12.0 10.2 0.51 10.8 10.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) SR-25 PF10500.9 EGE01387.1 - 0.33 10.5 24.0 0.027 14.1 12.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5521 PF17659.1 EGE01387.1 - 0.39 8.5 5.5 0.5 8.1 5.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) LCD1 PF09798.9 EGE01387.1 - 2.3 6.6 7.6 3.3 6.1 7.6 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2828 PF11443.8 EGE01387.1 - 2.5 6.1 12.3 3.5 5.6 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC27 PF09507.10 EGE01387.1 - 2.7 7.3 24.5 3.8 6.8 24.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LMBR1 PF04791.16 EGE01387.1 - 3.2 6.5 3.3 4.1 6.2 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DAGAT PF03982.13 EGE01389.1 - 2.7e-90 302.3 0.0 3.3e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EGE01389.1 - 0.055 13.2 3.2 0.12 12.1 3.2 1.5 1 0 0 1 1 1 0 Rer1 family NOGCT PF08155.11 EGE01390.1 - 0.082 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 NOGCT (NUC087) domain Ank_2 PF12796.7 EGE01392.1 - 1.5e-76 253.0 9.1 4.9e-15 55.9 0.0 6.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE01392.1 - 8.7e-49 163.3 0.7 4.7e-08 33.4 0.0 9.3 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE01392.1 - 1.9e-42 138.3 2.0 0.001 19.4 0.0 11.9 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 EGE01392.1 - 9.4e-42 140.5 8.1 5.5e-09 36.1 0.0 7.7 3 1 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 EGE01392.1 - 1e-41 139.6 10.9 0.00028 21.2 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat PEGA PF08308.11 EGE01392.1 - 0.0027 17.6 0.0 22 5.1 0.0 3.9 4 0 0 4 4 4 0 PEGA domain VWA_3_C PF18571.1 EGE01392.1 - 0.006 16.4 1.3 29 4.6 0.0 4.9 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain F-box-like PF12937.7 EGE01392.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like DUF4988 PF16378.5 EGE01392.1 - 0.066 12.9 0.0 9.9 5.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function Kinesin PF00225.23 EGE01393.1 - 7.5e-68 228.9 0.8 4.4e-65 219.8 1.2 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGE01393.1 - 5.9e-05 23.0 1.0 0.42 10.5 0.0 3.6 4 0 0 4 4 4 2 Microtubule binding Cytochrom_B562 PF07361.11 EGE01393.1 - 0.0075 16.9 0.8 0.059 14.0 0.0 2.7 2 0 0 2 2 2 1 Cytochrome b562 GNAT_acetyltr_2 PF13718.6 EGE01393.1 - 0.019 14.4 0.8 1 8.7 0.4 2.4 2 0 0 2 2 2 0 GNAT acetyltransferase 2 MoCF_biosynth PF00994.24 EGE01393.1 - 0.047 13.3 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Probable molybdopterin binding domain FlxA PF14282.6 EGE01393.1 - 0.063 13.3 6.2 0.13 12.3 1.8 3.4 3 0 0 3 3 3 0 FlxA-like protein MPS2 PF17060.5 EGE01393.1 - 0.11 11.7 1.3 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 Lebercilin PF15619.6 EGE01393.1 - 0.21 11.2 15.3 0.14 11.8 1.6 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 EGE01393.1 - 0.98 9.8 7.7 1.4 9.3 0.4 3.4 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Tho2 PF11262.8 EGE01393.1 - 1.1 8.4 4.3 1.9 7.6 4.3 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 RNA_pol_3_Rpc31 PF11705.8 EGE01395.1 - 0.00021 21.6 1.0 0.00021 21.6 1.0 3.0 2 1 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 BAF1_ABF1 PF04684.13 EGE01395.1 - 0.41 9.6 6.4 0.036 13.1 1.3 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 EGE01395.1 - 6.8 5.4 9.2 6.1 5.5 4.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Spem1 PF15670.5 EGE01395.1 - 9.2 5.8 11.0 6.9 6.2 8.4 2.0 2 0 0 2 2 2 0 Spermatid maturation protein 1 TPR_14 PF13428.6 EGE01396.1 - 2.5e-08 34.1 3.2 0.026 15.3 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE01396.1 - 8.6e-07 29.4 0.4 0.054 14.0 0.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE01396.1 - 5.1e-06 26.3 0.0 0.0062 16.7 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE01396.1 - 4.1e-05 23.7 0.0 0.14 12.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE01396.1 - 9.2e-05 22.3 1.1 0.037 14.2 0.0 4.2 5 1 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EGE01396.1 - 0.00084 19.3 0.0 0.16 11.9 0.0 2.3 1 1 1 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_11 PF13414.6 EGE01396.1 - 0.013 15.2 0.1 2.6 7.8 0.1 3.5 2 1 1 3 3 3 0 TPR repeat TPR_16 PF13432.6 EGE01396.1 - 0.018 15.7 1.0 2.3 9.0 0.0 3.7 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGE01396.1 - 0.035 13.9 0.0 0.48 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGE01396.1 - 0.06 13.6 1.6 17 5.8 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF615 PF04751.14 EGE01396.1 - 0.061 13.3 0.2 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF615) TPR_9 PF13371.6 EGE01396.1 - 0.13 12.4 0.8 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.20 EGE01397.1 - 2.3e-75 254.1 0.0 4.8e-75 253.1 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGE01397.1 - 1.1e-06 28.9 0.0 0.0022 18.1 0.0 2.3 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGE01397.1 - 0.012 15.8 0.2 20 5.8 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat RAMP4 PF06624.12 EGE01398.1 - 4.5e-22 77.9 0.1 5.2e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 GST_C PF00043.25 EGE01400.1 - 2.8e-14 53.1 0.0 1.2e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE01400.1 - 9.4e-14 51.5 0.0 1.6e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE01400.1 - 8.6e-13 48.5 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE01400.1 - 8.7e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGE01400.1 - 1.9e-08 34.5 0.0 7.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE01400.1 - 2.2e-08 34.0 0.1 4.4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 EGE01402.1 - 5.2e-15 55.5 0.0 8.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01402.1 - 1.2e-11 44.4 0.0 2.1e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE01402.1 - 4.6e-05 22.9 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like KxDL PF10241.9 EGE01403.1 - 0.02 15.1 0.2 0.03 14.6 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein COG5 PF10392.9 EGE01403.1 - 0.047 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4446 PF14584.6 EGE01403.1 - 0.16 12.0 0.3 0.16 12.0 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Vfa1 PF08432.10 EGE01403.1 - 5.2 7.4 12.7 5.8 7.2 12.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 IF-2B PF01008.17 EGE01404.1 - 2e-70 237.2 0.7 2.4e-70 237.0 0.7 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LSM PF01423.22 EGE01405.1 - 8.9e-20 70.2 0.0 1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE01405.1 - 0.0022 18.1 0.1 0.0026 17.9 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGE01405.1 - 0.032 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 EGE01405.1 - 0.09 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Hfq protein DUF1106 PF06523.11 EGE01405.1 - 0.13 12.3 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Rad60-SLD PF11976.8 EGE01406.1 - 9.8e-24 83.0 1.1 2.4e-19 68.9 0.7 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGE01406.1 - 3.4e-05 23.5 0.4 0.0063 16.2 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin family Rxt3 PF08642.10 EGE01406.1 - 6.4 7.6 12.0 2.1 9.1 0.5 3.0 3 1 0 3 3 3 0 Histone deacetylation protein Rxt3 Trm112p PF03966.16 EGE01407.1 - 1.5e-14 54.3 0.1 1.9e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein N-SET PF11764.8 EGE01408.1 - 2.8e-58 196.8 0.2 2.8e-58 196.8 0.2 2.4 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EGE01408.1 - 2.3e-27 94.4 0.3 5.9e-27 93.1 0.3 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EGE01408.1 - 8.9e-20 71.8 0.2 8.9e-20 71.8 0.2 3.4 3 0 0 3 3 3 1 SET domain RRM_1 PF00076.22 EGE01408.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase_6 PF13522.6 EGE01409.1 - 5.4e-18 65.5 0.0 9.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGE01409.1 - 3.2e-11 43.2 0.0 5.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGE01409.1 - 9.6e-05 21.4 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS PF01380.22 EGE01409.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 SIS domain GATase_2 PF00310.21 EGE01409.1 - 0.11 11.2 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Atg8 PF02991.16 EGE01411.1 - 1.9e-34 117.9 0.0 2.2e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGE01411.1 - 0.0021 18.4 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Peptidase_S10 PF00450.22 EGE01412.1 - 1.1e-91 308.3 0.1 1.4e-91 308.0 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EGE01412.1 - 0.11 13.1 0.0 12 6.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_16 PF10294.9 EGE01413.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MFS_1 PF07690.16 EGE01415.1 - 3.3e-39 134.8 32.1 1.2e-36 126.4 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01415.1 - 3e-09 36.3 9.7 3e-09 36.3 9.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGE01415.1 - 0.00022 19.7 4.6 0.0043 15.4 0.0 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EGE01415.1 - 0.0003 20.2 26.3 0.008 15.5 5.4 3.3 2 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGE01415.1 - 0.091 11.6 20.1 0.075 11.9 3.8 3.6 2 2 1 3 3 3 0 MFS_1 like family AlaDh_PNT_N PF05222.15 EGE01418.1 - 2.2e-27 96.0 0.0 3.4e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGE01418.1 - 0.0014 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAR PF03114.18 EGE01419.1 - 1.2e-66 224.8 7.7 1.5e-66 224.5 7.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGE01419.1 - 3.9e-13 48.8 0.0 8.1e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE01419.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGE01419.1 - 2.2e-07 30.4 0.1 6.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 EGE01419.1 - 0.11 12.1 5.4 3.3 7.2 2.2 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BAR_3 PF16746.5 EGE01419.1 - 0.5 10.0 10.1 2.1 8.0 10.1 2.2 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 EGE01419.1 - 0.75 9.0 8.7 1.2 8.3 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 EGE01419.1 - 2.6 8.6 10.8 12 6.4 5.0 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 EGE01419.1 - 3.2 7.9 12.1 0.97 9.5 0.6 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Asp PF00026.23 EGE01420.1 - 2.3e-60 204.6 4.1 2.9e-60 204.3 4.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGE01420.1 - 7.9e-05 23.0 2.9 0.041 14.1 0.3 3.3 2 1 2 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE01420.1 - 0.0018 18.9 0.7 1.6 9.4 0.3 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EGE01420.1 - 0.0031 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal AvrPphF-ORF-2 PF09143.10 EGE01420.1 - 0.058 13.3 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 AvrPphF-ORF-2 GST_N PF02798.20 EGE01421.1 - 3.2e-17 62.6 0.0 1.1e-16 60.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE01421.1 - 6.9e-17 61.6 0.0 2e-16 60.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE01421.1 - 4.3e-10 39.7 0.0 9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGE01421.1 - 3.2e-09 36.9 0.0 4.8e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE01421.1 - 0.0002 21.5 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.17 EGE01422.1 - 4.2e-80 269.6 14.7 4.5e-52 177.3 5.7 2.0 1 1 1 2 2 2 2 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGE01422.1 - 0.016 14.7 1.4 0.02 14.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Abhydrolase_6 PF12697.7 EGE01423.1 - 0.00041 21.0 0.0 0.00074 20.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 EGE01423.1 - 0.0062 16.9 0.1 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase PF06745.13 EGE01423.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC ATP_transf PF09830.9 EGE01424.1 - 4.3e-15 55.6 0.1 4.3e-15 55.6 0.1 1.7 2 0 0 2 2 2 1 ATP adenylyltransferase Copper-bind PF00127.20 EGE01425.1 - 0.00049 20.5 0.1 0.00083 19.8 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cas_csx3 PF09620.10 EGE01425.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) LEA_6 PF10714.9 EGE01425.1 - 0.018 15.1 1.5 0.03 14.4 1.5 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Cupredoxin_1 PF13473.6 EGE01425.1 - 0.073 13.2 0.2 0.33 11.1 0.2 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain Aminotran_5 PF00266.19 EGE01426.1 - 2.2e-94 316.4 0.0 2.7e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGE01426.1 - 5.3e-07 29.2 0.0 7.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGE01426.1 - 8.9e-06 25.2 0.0 5.7e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EGE01426.1 - 0.0047 15.7 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EGE01426.1 - 0.09 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 EGE01427.1 - 2.7e-119 398.8 0.0 3.3e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 EGE01428.1 - 4.2e-36 123.5 0.0 7e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGE01428.1 - 2.6e-21 75.3 0.0 1.5e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.8 EGE01428.1 - 0.0018 18.3 1.6 0.0029 17.7 1.6 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-Q PF13094.6 EGE01428.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.6 EGE01428.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 EGE01429.1 - 1e-10 41.7 0.0 0.053 13.8 0.0 4.8 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE01429.1 - 1.6e-09 38.3 8.5 0.007 17.2 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGE01429.1 - 0.0024 16.9 0.4 1.4 7.8 0.0 3.5 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pet127 PF08634.10 EGE01430.1 - 2.4e-118 394.5 0.0 3.5e-118 394.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.6 EGE01432.1 - 0.31 11.2 6.8 21 5.5 0.1 4.9 4 0 0 4 4 4 0 Leucine Rich repeat SelP_N PF04592.14 EGE01432.1 - 1.3 8.3 18.0 0.72 9.2 1.5 2.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region LHC PF00556.20 EGE01433.1 - 0.16 12.2 0.4 0.31 11.3 0.4 1.5 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Gly_transf_sug PF04488.15 EGE01434.1 - 5e-19 68.7 0.0 9.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif MMR1 PF08505.10 EGE01435.1 - 0.05 13.9 3.2 0.063 13.6 3.2 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Abhydrolase_6 PF12697.7 EGE01436.1 - 1.2e-15 58.8 0.8 1.5e-15 58.4 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE01436.1 - 5.5e-09 36.0 0.0 7.5e-08 32.3 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.8 EGE01436.1 - 0.082 12.4 0.1 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Bul1_N PF04425.12 EGE01438.1 - 3.1e-05 22.9 0.4 7.1e-05 21.7 0.3 1.5 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.29 EGE01438.1 - 0.00075 19.6 0.0 0.0022 18.0 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EGE01438.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 Bul1 C terminus Abhydrolase_3 PF07859.13 EGE01439.1 - 4.9e-05 23.3 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGE01439.1 - 8.5e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGE01439.1 - 9.3e-05 22.2 0.1 0.011 15.4 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE01439.1 - 0.00012 21.4 0.0 0.00089 18.6 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE01439.1 - 0.0028 18.3 2.7 0.0054 17.4 2.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGE01439.1 - 0.028 13.9 0.0 0.073 12.5 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family LIP PF03583.14 EGE01439.1 - 0.045 13.1 0.1 8.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AA_permease PF00324.21 EGE01440.1 - 1e-137 459.6 43.8 1.3e-137 459.3 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE01440.1 - 6.8e-38 130.6 48.0 8.6e-38 130.3 48.0 1.1 1 0 0 1 1 1 1 Amino acid permease OppC_N PF12911.7 EGE01440.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.4 5 0 0 5 5 5 0 N-terminal TM domain of oligopeptide transport permease C MFS_1 PF07690.16 EGE01441.1 - 4.2e-22 78.5 33.2 4.2e-22 78.5 33.2 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01441.1 - 2e-06 27.0 8.5 2e-06 27.0 8.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.22 EGE01443.1 - 1.1e-54 186.0 0.0 1.4e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.20 EGE01444.1 - 8.9e-16 58.7 0.0 1.4e-15 58.0 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGE01444.1 - 3.5e-07 31.1 0.0 4.1e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE01444.1 - 0.058 13.0 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cytokin_check_N PF10407.9 EGE01445.1 - 0.00035 20.5 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.25 EGE01446.1 - 9.4e-43 146.5 0.0 1.5e-40 139.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EGE01446.1 - 6.1e-40 136.3 0.1 1.5e-39 135.1 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGE01446.1 - 1.7e-20 73.4 0.0 2.1e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EGE01446.1 - 0.00011 21.9 0.1 0.12 12.4 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 EGE01446.1 - 0.00071 19.0 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGE01446.1 - 0.0018 17.1 0.0 0.004 16.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase PQQ_2 PF13360.6 EGE01446.1 - 0.0055 16.3 0.1 0.028 14.0 0.1 2.0 1 1 0 1 1 1 1 PQQ-like domain YrbL-PhoP_reg PF10707.9 EGE01446.1 - 0.0071 15.9 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL SRP-alpha_N PF04086.13 EGE01446.1 - 6.7 6.5 8.7 11 5.8 8.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pro_isomerase PF00160.21 EGE01447.1 - 1.8e-51 174.5 0.1 4.1e-51 173.4 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGE01447.1 - 8.9e-08 32.7 0.2 0.21 12.5 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 EGE01448.1 - 2.6e-139 465.0 12.7 2.9e-139 464.8 12.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pam17 PF08566.10 EGE01451.1 - 1.8e-66 223.1 0.1 2.4e-66 222.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Fungal_trans_2 PF11951.8 EGE01452.1 - 7.6e-53 179.7 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01452.1 - 1.2e-08 34.9 11.1 2.2e-08 34.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIB PF02201.18 EGE01453.1 - 2.3e-28 97.9 0.1 5.8e-28 96.6 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EGE01453.1 - 1.6e-14 53.5 0.1 4e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain Mcm10 PF09332.11 EGE01453.1 - 0.0059 16.1 3.7 0.007 15.8 3.7 1.1 1 0 0 1 1 1 1 Mcm10 replication factor CheR_N PF03705.15 EGE01453.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain RFXA_RFXANK_bdg PF15289.6 EGE01453.1 - 0.075 13.4 2.8 0.087 13.2 1.3 1.8 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain eIF2A PF08662.11 EGE01454.1 - 1.7e-36 125.9 5.9 2.6e-34 118.8 1.3 3.9 3 3 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EGE01454.1 - 3.1e-07 30.1 0.1 8.6e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EGE01454.1 - 0.0021 18.8 0.9 0.23 12.4 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat PRP3 PF08572.10 EGE01454.1 - 0.0061 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DLH PF01738.18 EGE01455.1 - 2.4e-28 99.2 0.0 2.7e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGE01455.1 - 0.097 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EGE01455.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family NmrA PF05368.13 EGE01456.1 - 9e-11 41.8 0.0 9.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE01456.1 - 2.1e-08 34.3 0.0 3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGE01456.1 - 0.00012 22.3 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Peptidase_S10 PF00450.22 EGE01457.1 - 7.7e-75 252.9 1.1 9.3e-75 252.6 1.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_1 PF00561.20 EGE01458.1 - 1.4e-32 113.3 0.0 1.8e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE01458.1 - 2.6e-16 59.7 0.0 4.7e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE01458.1 - 2.3e-09 38.2 0.1 3.3e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGE01458.1 - 0.00015 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EGE01458.1 - 0.014 15.1 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 EGE01458.1 - 0.045 13.4 0.1 0.15 11.6 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Ndr PF03096.14 EGE01458.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.18 EGE01459.1 - 2.1e-18 66.3 2.7 5e-18 65.1 2.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGE01459.1 - 0.00019 21.7 14.4 0.0021 18.4 1.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE01459.1 - 0.0056 17.4 13.9 0.017 15.9 0.8 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger SPX PF03105.19 EGE01459.1 - 0.026 14.5 5.5 0.051 13.5 5.5 1.6 1 0 0 1 1 1 0 SPX domain zf-met PF12874.7 EGE01459.1 - 0.094 13.1 0.1 0.28 11.6 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EGE01459.1 - 0.41 11.0 3.3 1.1 9.6 3.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon RSN1_7TM PF02714.15 EGE01460.1 - 6e-86 288.1 27.7 4.6e-85 285.3 24.1 2.4 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGE01460.1 - 1.9e-45 154.4 2.3 1.9e-45 154.4 2.3 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EGE01460.1 - 1.1e-27 96.0 0.4 1.1e-26 92.8 0.2 2.4 3 0 0 3 3 3 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EGE01460.1 - 7.8e-27 94.6 0.1 1.2e-26 94.0 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Rubella_E2 PF05749.11 EGE01460.1 - 0.053 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 zf-C3HC4_3 PF13920.6 EGE01461.1 - 5e-07 29.5 9.5 5e-07 29.5 9.5 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE01461.1 - 3.7 7.5 20.1 0.064 13.1 11.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 EGE01462.1 - 1.8e-61 207.5 0.4 3.2e-61 206.6 0.4 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE01462.1 - 1.6e-32 113.3 1.3 3.7e-32 112.1 1.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGE01462.1 - 4.4e-12 46.2 0.5 1.2e-10 41.6 0.1 2.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGE01462.1 - 1.7e-11 44.5 0.2 6.4e-11 42.7 0.2 2.0 1 0 0 1 1 1 1 MutS domain II RasGEF_N_2 PF14663.6 EGE01462.1 - 0.0086 16.5 1.8 6.6 7.2 0.1 3.5 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain AAA_30 PF13604.6 EGE01462.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3213 PF11491.8 EGE01462.1 - 0.09 13.0 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) HMGL-like PF00682.19 EGE01462.1 - 0.096 12.2 0.3 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 HMGL-like AAA_14 PF13173.6 EGE01462.1 - 0.11 12.5 0.0 0.46 10.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGE01463.1 - 6.4e-56 185.0 24.8 1.4e-11 44.7 0.4 8.6 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE01463.1 - 2.4e-22 79.0 4.8 0.00025 21.3 0.1 5.7 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE01463.1 - 2.8e-07 29.6 3.8 0.45 9.1 0.0 5.2 5 1 0 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGE01463.1 - 2.1e-06 27.0 0.0 0.072 12.0 0.0 4.8 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGE01463.1 - 1.2e-05 25.3 0.5 0.044 13.7 0.1 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 EGE01463.1 - 2.6e-05 24.6 0.0 5.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 EGE01463.1 - 0.013 14.8 0.0 16 4.7 0.0 3.9 3 1 1 4 4 4 0 WD40-like domain DUF4550 PF15084.6 EGE01463.1 - 0.016 15.6 0.1 0.15 12.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) FAD_binding_9 PF08021.11 EGE01463.1 - 0.036 14.3 0.0 0.61 10.3 0.0 2.6 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.12 EGE01463.1 - 0.34 10.9 2.4 30 4.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Sec10 PF07393.11 EGE01464.1 - 2.6e-152 508.8 0.1 3.3e-152 508.5 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EGE01464.1 - 1.8e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE01464.1 - 8.4e-05 22.3 0.3 0.00022 21.0 0.0 1.8 2 0 0 2 2 2 1 F-box domain RINT1_TIP1 PF04437.13 EGE01464.1 - 0.014 14.3 0.1 0.048 12.6 0.0 1.8 2 0 0 2 2 2 0 RINT-1 / TIP-1 family AAA PF00004.29 EGE01465.1 - 1.8e-30 106.1 0.0 3.5e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGE01465.1 - 4.5e-06 27.0 0.1 2.2e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE01465.1 - 1.1e-05 25.9 0.0 2.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGE01465.1 - 3.5e-05 24.4 0.0 8.2e-05 23.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EGE01465.1 - 0.00016 21.3 0.0 0.00038 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGE01465.1 - 0.00047 20.2 0.1 0.0012 18.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGE01465.1 - 0.00048 20.2 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGE01465.1 - 0.0005 19.9 0.1 0.016 15.0 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGE01465.1 - 0.00061 20.2 0.1 0.0019 18.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 EGE01465.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGE01465.1 - 0.0012 18.7 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 EGE01465.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 EGE01465.1 - 0.0053 16.7 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EGE01465.1 - 0.011 15.7 0.1 0.44 10.4 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGE01465.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EGE01465.1 - 0.013 15.7 0.0 0.026 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGE01465.1 - 0.014 14.8 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EGE01465.1 - 0.017 14.8 0.2 0.04 13.6 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase IstB_IS21 PF01695.17 EGE01465.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGE01465.1 - 0.021 15.3 0.3 0.18 12.3 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGE01465.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGE01465.1 - 0.033 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 EGE01465.1 - 0.044 12.4 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGE01465.1 - 0.046 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGE01465.1 - 0.049 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Rad17 PF03215.15 EGE01465.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EGE01465.1 - 0.071 13.4 0.2 0.36 11.1 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGE01465.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EGE01465.1 - 0.087 12.1 0.0 0.26 10.6 0.0 1.7 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain TIP49 PF06068.13 EGE01465.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Cytochrom_C1 PF02167.15 EGE01466.1 - 9.9e-93 309.9 0.0 1.2e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family SbcCD_C PF13558.6 EGE01466.1 - 0.003 17.8 0.2 0.0061 16.8 0.2 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrome_CBB3 PF13442.6 EGE01466.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.6 EGE01467.1 - 1.1e-05 25.7 0.0 0.00014 22.2 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 EGE01470.1 - 1.3e-102 342.4 0.0 1.6e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family MFS_1 PF07690.16 EGE01471.1 - 6.6e-20 71.3 27.0 6.6e-20 71.3 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RSN1_7TM PF02714.15 EGE01472.1 - 1.1e-81 274.2 21.0 2.5e-81 273.0 21.0 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGE01472.1 - 4.8e-41 140.9 0.0 7.3e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGE01472.1 - 2.3e-32 111.9 0.6 2.3e-32 111.9 0.6 2.6 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EGE01472.1 - 0.0016 17.4 2.3 0.0016 17.4 2.3 2.3 3 0 0 3 3 3 1 Calcium-activated chloride channel GDE_C PF06202.14 EGE01473.1 - 3.6e-122 408.0 0.0 4.8e-122 407.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hDGE_amylase PF14701.6 EGE01473.1 - 2.1e-121 406.1 0.0 3.2e-121 405.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 EGE01473.1 - 2.1e-50 171.8 0.0 4.5e-50 170.7 0.0 1.5 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme RIX1 PF08167.12 EGE01473.1 - 0.17 11.6 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis NAD_Gly3P_dh_N PF01210.23 EGE01474.1 - 4.6e-45 153.4 0.0 7.6e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EGE01474.1 - 3.3e-43 147.4 0.1 5.7e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SLX9 PF15341.6 EGE01475.1 - 5e-38 130.5 3.5 5e-38 130.5 3.5 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Pilin_GH PF16734.5 EGE01475.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative ThiF PF00899.21 EGE01476.1 - 1.8e-57 194.5 0.0 2.6e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGE01476.1 - 4.9e-09 36.7 0.0 1.3e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Spc24 PF08286.11 EGE01476.1 - 0.024 14.9 0.5 0.046 14.0 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 NAD_binding_7 PF13241.6 EGE01476.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGE01476.1 - 0.068 12.4 0.7 0.1 11.8 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain FlxA PF14282.6 EGE01476.1 - 0.069 13.1 4.1 0.12 12.4 4.1 1.4 1 0 0 1 1 1 0 FlxA-like protein Shikimate_DH PF01488.20 EGE01476.1 - 0.084 12.9 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGE01476.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EGE01476.1 - 0.11 12.1 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase YlqD PF11068.8 EGE01476.1 - 0.11 12.8 2.7 0.19 12.1 2.7 1.3 1 0 0 1 1 1 0 YlqD protein PRKG1_interact PF15898.5 EGE01476.1 - 0.13 13.2 2.3 0.22 12.4 2.3 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ABC_tran_CTD PF16326.5 EGE01476.1 - 0.24 11.7 4.6 0.37 11.1 4.6 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 EGE01476.1 - 0.29 10.5 2.3 0.41 10.1 2.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DivIC PF04977.15 EGE01476.1 - 0.47 10.3 3.7 0.83 9.5 3.7 1.3 1 0 0 1 1 1 0 Septum formation initiator HR1 PF02185.16 EGE01476.1 - 1.6 8.9 6.0 3.2 7.9 6.0 1.5 1 0 0 1 1 1 0 Hr1 repeat DHR10 PF18595.1 EGE01476.1 - 2.4 8.2 8.3 5 7.2 8.3 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DPBB_1 PF03330.18 EGE01477.1 - 4.8e-09 36.4 0.1 2.2e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EGE01477.1 - 0.066 13.1 0.1 0.09 12.6 0.1 1.2 1 0 0 1 1 1 0 Barwin family MARVEL PF01284.23 EGE01477.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Bac_export_3 PF01313.19 EGE01477.1 - 0.27 11.2 2.9 0.41 10.6 2.9 1.2 1 0 0 1 1 1 0 Bacterial export proteins, family 3 PMP1_2 PF08114.11 EGE01478.1 - 0.0006 19.5 2.9 0.0006 19.5 2.9 1.4 1 1 0 1 1 1 1 ATPase proteolipid family DUF4381 PF14316.6 EGE01478.1 - 0.0022 18.2 0.1 0.0024 18.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) 5TM-5TMR_LYT PF07694.12 EGE01478.1 - 0.032 13.8 0.2 0.039 13.5 0.2 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT PDR_CDR PF06422.12 EGE01478.1 - 0.091 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 CDR ABC transporter Sec61_beta PF03911.16 EGE01478.1 - 0.17 12.0 2.5 0.22 11.6 2.5 1.2 1 0 0 1 1 1 0 Sec61beta family NAD_binding_11 PF14833.6 EGE01479.1 - 5.5e-42 142.8 0.6 6.7e-27 94.2 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EGE01479.1 - 2.7e-36 125.1 0.1 5.3e-36 124.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGE01479.1 - 0.0005 20.0 0.1 0.00095 19.1 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGE01479.1 - 0.0057 17.2 0.1 0.024 15.2 0.1 2.3 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGE01479.1 - 0.015 14.9 0.1 0.04 13.6 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EGE01479.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F_bP_aldolase PF01116.20 EGE01480.1 - 2e-83 280.1 0.0 2.3e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II OrfB_IS605 PF01385.19 EGE01480.1 - 0.16 12.2 0.1 0.64 10.3 0.0 1.9 2 0 0 2 2 2 0 Probable transposase Fer2_3 PF13085.6 EGE01481.1 - 1.2e-32 112.1 0.1 2e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGE01481.1 - 9.9e-09 35.6 5.7 9.9e-09 35.6 5.7 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGE01481.1 - 1.7e-07 31.5 6.3 1.7e-07 31.5 6.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGE01481.1 - 8.4e-07 29.0 2.5 8.4e-07 29.0 2.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EGE01481.1 - 0.0021 18.6 4.3 0.0021 18.6 4.3 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGE01481.1 - 0.0049 16.8 0.4 0.0049 16.8 0.4 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 EGE01481.1 - 0.17 11.8 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain RTA1 PF04479.13 EGE01482.1 - 2.4e-72 242.9 4.5 2.9e-72 242.6 4.5 1.1 1 0 0 1 1 1 1 RTA1 like protein CBP_BcsF PF11120.8 EGE01482.1 - 0.0067 16.5 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsF DUF3493 PF11998.8 EGE01482.1 - 0.057 13.6 0.7 0.23 11.6 0.1 2.3 1 1 2 3 3 3 0 Low psii accumulation1 / Rep27 Abhydrolase_9_N PF15420.6 EGE01482.1 - 0.13 12.3 1.4 0.26 11.3 1.0 1.6 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4013 PF13197.6 EGE01482.1 - 1.3 8.8 14.4 0.16 11.8 2.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4013) Velvet PF11754.8 EGE01484.1 - 5.3e-89 298.4 0.3 5.3e-89 298.4 0.3 2.1 2 0 0 2 2 2 1 Velvet factor Git3 PF11710.8 EGE01485.1 - 1.1e-27 97.2 7.2 2.1e-27 96.2 7.2 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EGE01485.1 - 3.9e-10 39.6 0.0 3.9e-10 39.6 0.0 2.7 3 1 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EGE01485.1 - 0.0096 15.1 7.2 0.016 14.4 7.2 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor SCIMP PF15050.6 EGE01485.1 - 0.21 12.1 0.3 55 4.2 0.0 3.3 3 0 0 3 3 3 0 SCIMP protein Syndecan PF01034.20 EGE01485.1 - 0.44 10.5 2.3 0.77 9.7 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain Orf78 PF06024.12 EGE01485.1 - 2.1 8.7 3.3 32 4.9 0.0 2.9 3 0 0 3 3 3 0 Orf78 (ac78) HKR_ArcB_TM PF18415.1 EGE01487.1 - 0.035 14.9 2.2 0.035 14.9 2.2 2.5 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain EptA_B_N PF08019.12 EGE01487.1 - 0.087 12.7 14.5 0.26 11.2 0.7 2.8 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF1614 PF07758.11 EGE01487.1 - 2.6 8.0 7.6 0.11 12.4 1.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1614) HhH-GPD PF00730.25 EGE01490.1 - 4e-08 33.7 0.0 4.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4332 PF14229.6 EGE01490.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Fasciclin PF02469.22 EGE01491.1 - 3.4e-33 114.6 0.1 3e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain G_glu_transpept PF01019.21 EGE01492.1 - 1.6e-165 551.8 0.0 1.8e-165 551.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase AAA PF00004.29 EGE01494.1 - 1.6e-45 154.7 0.1 8.1e-45 152.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGE01494.1 - 3.5e-10 39.7 0.1 2.1e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EGE01494.1 - 6.8e-09 35.8 0.4 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGE01494.1 - 4.8e-08 33.3 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGE01494.1 - 1.3e-07 32.2 0.5 3.7e-05 24.2 0.0 3.0 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EGE01494.1 - 2.8e-06 26.7 0.0 5.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGE01494.1 - 4.3e-05 23.8 1.2 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGE01494.1 - 0.00014 21.7 0.1 0.00069 19.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGE01494.1 - 0.00023 21.4 0.0 0.0016 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGE01494.1 - 0.00036 20.1 0.0 0.0026 17.3 0.1 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_3 PF17862.1 EGE01494.1 - 0.00039 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EGE01494.1 - 0.00057 20.4 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGE01494.1 - 0.0013 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGE01494.1 - 0.0015 18.5 0.1 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGE01494.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EGE01494.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 EGE01494.1 - 0.0035 17.3 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EGE01494.1 - 0.0052 16.5 0.1 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGE01494.1 - 0.0056 16.5 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGE01494.1 - 0.0075 15.7 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGE01494.1 - 0.0075 16.2 0.3 0.11 12.4 0.0 2.6 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 EGE01494.1 - 0.0091 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EGE01494.1 - 0.01 15.3 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EGE01494.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGE01494.1 - 0.024 14.3 0.2 0.055 13.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EGE01494.1 - 0.04 13.3 0.8 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC Bac_DnaA PF00308.18 EGE01494.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 EGE01494.1 - 0.047 13.6 1.1 0.33 10.8 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EGE01494.1 - 0.053 13.3 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGE01494.1 - 0.078 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 EGE01494.1 - 0.078 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 EGE01494.1 - 0.087 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_25 PF13481.6 EGE01494.1 - 0.093 12.3 1.3 0.27 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 EGE01494.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EGE01494.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGE01494.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Parvo_NS1 PF01057.17 EGE01494.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 EGE01495.1 - 4.9e-109 364.6 0.4 5.9e-109 364.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGE01495.1 - 5.6e-15 56.0 3.4 1.1e-12 48.6 2.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE01495.1 - 3e-05 24.6 0.4 0.51 11.0 0.0 3.6 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EGE01495.1 - 0.00079 19.2 0.0 0.012 15.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGE01495.1 - 0.0027 18.2 0.1 5.3 7.7 0.1 3.3 3 2 0 3 3 3 2 gag-polyprotein putative aspartyl protease NIF PF03031.18 EGE01496.1 - 2.4e-27 95.6 0.0 4.7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGE01496.1 - 1.8e-09 37.8 0.0 7.3e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGE01496.1 - 1.2e-07 32.1 0.2 1.8e-05 25.1 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGE01496.1 - 5.3e-06 26.3 0.4 1.2e-05 25.1 0.4 1.6 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl_2 PF13533.6 EGE01496.1 - 0.0013 18.5 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Biotin-lipoyl like RTT107_BRCT_5 PF16770.5 EGE01496.1 - 0.0035 17.2 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EGE01496.1 - 0.0072 16.4 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGE01496.1 - 0.15 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain MARVEL PF01284.23 EGE01498.1 - 0.00013 22.0 15.0 0.00023 21.2 14.8 1.6 1 1 0 1 1 1 1 Membrane-associating domain Arginase PF00491.21 EGE01499.1 - 1.5e-39 136.2 0.0 1.8e-29 103.1 0.0 2.0 1 1 1 2 2 2 2 Arginase family GatB_N PF02934.15 EGE01500.1 - 4.8e-97 324.6 0.0 6.1e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGE01500.1 - 6.9e-24 84.4 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 GatB domain DBR1 PF05011.13 EGE01501.1 - 0.062 13.7 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain ECH_1 PF00378.20 EGE01504.1 - 3.1e-41 141.4 0.0 5.8e-41 140.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE01504.1 - 4.7e-28 98.6 0.0 6.3e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pox_P21 PF05313.12 EGE01504.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NB-ARC PF00931.22 EGE01505.1 - 1.8e-07 30.6 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PGAP1 PF07819.13 EGE01505.1 - 8.3e-07 28.9 0.0 5.4e-06 26.3 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 EGE01505.1 - 1.7e-06 28.6 2.0 5.8e-05 23.5 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain DUF676 PF05057.14 EGE01505.1 - 3.2e-05 23.6 0.1 0.00011 21.8 0.1 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Zeta_toxin PF06414.12 EGE01505.1 - 0.0059 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGE01505.1 - 0.01 16.0 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGE01505.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EGE01505.1 - 0.016 15.8 0.0 0.016 15.8 0.0 2.7 2 2 0 2 2 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE01505.1 - 0.027 13.7 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ATPase PF06745.13 EGE01505.1 - 0.094 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 EGE01505.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain YtxH PF12732.7 EGE01507.1 - 0.79 10.3 8.9 1.9 9.1 8.9 1.7 1 1 0 1 1 1 0 YtxH-like protein Alanine_zipper PF11839.8 EGE01507.1 - 3.1 8.3 19.0 7.8 7.0 19.0 1.8 1 1 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein FHA PF00498.26 EGE01508.1 - 2.1e-12 47.2 0.0 4.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.16 EGE01509.1 - 5.3e-21 74.9 41.4 1.6e-20 73.4 21.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EGE01510.1 - 1.4e-32 113.0 1.5 1.8e-32 112.6 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ PF00226.31 EGE01511.1 - 2.9e-08 33.7 0.1 5.7e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain SUKH-4 PF14435.6 EGE01511.1 - 0.078 13.0 0.4 0.9 9.6 0.2 2.1 2 0 0 2 2 2 0 SUKH-4 immunity protein Abhydrolase_3 PF07859.13 EGE01512.1 - 3.3e-37 128.4 0.0 4.2e-36 124.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGE01512.1 - 0.00048 19.1 0.6 0.0036 16.2 0.6 2.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase M_domain PF12938.7 EGE01516.1 - 0.036 13.9 13.6 0.065 13.0 13.6 1.3 1 0 0 1 1 1 0 M domain of GW182 Homoserine_dh PF00742.19 EGE01519.1 - 3.4e-52 176.8 0.0 4.5e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EGE01519.1 - 2.8e-13 50.6 0.0 6.5e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 EGE01520.1 - 4.6e-28 97.4 10.5 4.6e-28 97.4 10.5 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4078) HTH_Tnp_Tc3_2 PF01498.18 EGE01521.1 - 2.2e-13 50.2 0.2 4e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EGE01521.1 - 2.9e-05 23.7 0.3 9.1e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EGE01521.1 - 0.00025 20.7 0.1 0.51 10.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-70, region 4 HTH_32 PF13565.6 EGE01521.1 - 0.00026 21.5 5.1 0.0016 19.0 0.0 2.9 1 1 2 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.15 EGE01521.1 - 0.00083 19.4 0.2 0.039 14.0 0.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.6 EGE01521.1 - 0.0042 17.1 0.3 0.025 14.6 0.0 2.4 2 1 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 EGE01521.1 - 0.007 16.5 0.3 0.045 13.9 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.6 EGE01521.1 - 0.022 14.5 0.6 0.13 12.1 0.0 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_IS630 PF01710.16 EGE01521.1 - 0.048 13.7 0.0 0.085 12.9 0.0 1.4 1 1 0 1 1 1 0 Transposase DUF3772 PF12607.8 EGE01521.1 - 0.8 9.5 4.9 0.54 10.1 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3772) ATG11 PF10377.9 EGE01522.1 - 3.5e-45 153.2 0.1 3.5e-45 153.2 0.1 3.4 4 1 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 EGE01522.1 - 1.1e-10 41.2 34.4 6.9e-08 32.0 0.0 4.0 4 1 0 4 4 4 3 Autophagy protein Apg17 ERM PF00769.19 EGE01522.1 - 0.00022 21.1 17.1 0.00022 21.1 17.1 5.4 6 0 0 6 6 6 2 Ezrin/radixin/moesin family Spc7 PF08317.11 EGE01522.1 - 0.004 16.1 19.1 0.004 16.1 19.1 6.1 4 2 3 7 7 7 4 Spc7 kinetochore protein Laminin_II PF06009.12 EGE01522.1 - 0.25 11.3 35.0 0.029 14.4 6.9 6.8 4 1 2 7 7 7 0 Laminin Domain II CENP-F_leu_zip PF10473.9 EGE01522.1 - 0.95 9.5 67.8 0.34 10.9 21.1 6.7 7 1 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps51 PF08700.11 EGE01522.1 - 3.7 7.7 9.1 2.2 8.4 1.8 4.3 3 1 0 4 4 4 0 Vps51/Vps67 Arm-DNA-bind_5 PF17293.2 EGE01522.1 - 7.7 7.0 7.0 79 3.8 1.3 3.9 2 1 1 3 3 3 0 Arm DNA-binding domain Fib_alpha PF08702.10 EGE01522.1 - 8.7 6.5 33.5 0.27 11.4 3.2 6.8 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.11 EGE01522.1 - 8.9 6.6 22.7 31 4.8 7.4 6.1 5 2 0 5 5 5 0 Protein of unknown function (DUF1319) CENP-H PF05837.12 EGE01523.1 - 5.4e-27 94.4 9.4 5.4e-27 94.4 9.4 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) SOAR PF16533.5 EGE01523.1 - 0.095 12.7 9.3 0.56 10.2 4.6 2.6 1 1 1 2 2 2 0 STIM1 Orai1-activating region Herpes_BLRF2 PF05812.12 EGE01523.1 - 0.66 10.1 7.7 3.2 7.9 1.2 2.6 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein Cas_DxTHG PF09455.10 EGE01523.1 - 3.6 7.1 8.2 0.89 9.1 5.0 1.6 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family Pex19 PF04614.12 EGE01525.1 - 4.6e-70 236.2 19.1 4.6e-70 236.2 19.1 2.0 1 1 1 2 2 2 1 Pex19 protein family DUF4327 PF14217.6 EGE01525.1 - 0.0012 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) ASF1_hist_chap PF04729.13 EGE01526.1 - 8e-48 162.3 0.0 1.3e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4407 PF14362.6 EGE01526.1 - 1 8.6 2.6 1.4 8.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 EGE01526.1 - 1.6 6.9 23.0 2 6.6 23.0 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 EGE01526.1 - 9.8 5.4 14.6 14 5.0 14.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Suf PF05843.14 EGE01527.1 - 5e-56 190.9 0.1 5e-56 190.9 0.1 4.7 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGE01527.1 - 3.8e-05 24.1 1.6 0.032 15.0 0.0 4.7 5 1 1 6 6 6 1 Tetratricopeptide repeat HAT PF02184.16 EGE01527.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 EGE01527.1 - 0.016 15.8 0.0 1 10.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Cdh1_DBD_1 PF18196.1 EGE01527.1 - 0.031 14.6 4.5 0.079 13.3 4.5 1.6 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Oxysterol_BP PF01237.18 EGE01528.1 - 5.3e-64 216.4 3.7 7.8e-62 209.2 3.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein POT1 PF02765.17 EGE01528.1 - 0.03 14.2 2.1 0.47 10.3 0.0 3.3 4 0 0 4 4 4 0 Telomeric single stranded DNA binding POT1/CDC13 RTA1 PF04479.13 EGE01529.1 - 2.1e-52 177.8 9.2 2.1e-52 177.8 9.2 1.4 2 0 0 2 2 2 1 RTA1 like protein CUE PF02845.16 EGE01530.1 - 2.4e-10 39.9 0.0 4.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain ELK PF03789.13 EGE01530.1 - 0.0062 16.6 0.2 0.011 15.8 0.2 1.3 1 0 0 1 1 1 1 ELK domain DUF2866 PF11065.8 EGE01531.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) DUF3446 PF11928.8 EGE01532.1 - 0.013 15.8 23.3 0.013 15.8 23.3 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain SPX PF03105.19 EGE01532.1 - 0.27 11.1 4.6 0.25 11.2 4.6 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 EGE01532.1 - 2.4 7.8 12.9 2.4 7.8 12.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 EGE01532.1 - 3.4 7.2 19.9 4.6 6.8 19.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 EGE01533.1 - 5.5 5.2 19.4 6.1 5.0 19.4 1.3 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EGE01533.1 - 8.6 5.3 12.0 10 5.0 12.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 UCH PF00443.29 EGE01534.1 - 1.3e-34 119.9 0.1 6.9e-30 104.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE01534.1 - 1.1e-10 41.6 0.4 1.1e-06 28.5 0.2 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_4 PF13717.6 EGE01534.1 - 0.31 11.0 7.0 1.7 8.6 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain F_bP_aldolase PF01116.20 EGE01536.1 - 2.6e-91 306.0 0.0 3e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RPA43_OB PF17875.1 EGE01537.1 - 0.017 15.8 2.3 0.051 14.2 0.1 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I SDA1 PF05285.12 EGE01537.1 - 0.038 13.4 12.2 0.05 13.0 12.2 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGE01537.1 - 0.042 12.6 0.1 0.042 12.6 0.1 1.1 1 0 0 1 1 1 0 Presenilin TMEM208_SND2 PF05620.11 EGE01537.1 - 0.047 13.5 0.7 1.4 8.7 0.1 2.1 1 1 1 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF5399 PF17377.2 EGE01537.1 - 0.082 12.7 0.8 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5399) PBP1_TM PF14812.6 EGE01537.1 - 0.083 13.3 1.4 0.083 13.3 1.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EGE01537.1 - 0.089 10.9 10.1 0.11 10.6 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi CLN3 PF02487.17 EGE01537.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 EGE01537.1 - 0.25 9.6 7.8 0.35 9.1 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FHIPEP PF00771.20 EGE01537.1 - 0.27 9.7 0.1 0.34 9.3 0.1 1.3 1 1 0 1 1 1 0 FHIPEP family DUF3682 PF12446.8 EGE01537.1 - 0.31 11.5 21.1 0.25 11.8 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) TRAP_alpha PF03896.16 EGE01537.1 - 0.36 10.0 2.2 0.24 10.6 0.2 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nop53 PF07767.11 EGE01537.1 - 0.6 9.4 15.7 0.86 8.9 15.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_pol_Rpc4 PF05132.14 EGE01537.1 - 0.61 10.5 3.3 1.1 9.7 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 SspB PF04386.13 EGE01537.1 - 1.7 8.5 6.0 2.3 8.1 6.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RNase_H2_suC PF08615.11 EGE01537.1 - 1.8 8.7 7.1 0.37 11.0 1.8 1.9 1 1 1 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) U1snRNP70_N PF12220.8 EGE01537.1 - 3.5 8.3 11.8 0.61 10.8 2.8 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Phage_Gp23 PF10669.9 EGE01537.1 - 3.8 7.9 11.7 0.15 12.4 1.4 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Ribosomal_60s PF00428.19 EGE01537.1 - 4.7 7.9 21.3 0.2 12.3 10.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAXIP1_C PF15364.6 EGE01537.1 - 5.3 7.4 14.4 5.8 7.2 8.3 2.0 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Conotoxin PF02950.17 EGE01537.1 - 7.2 7.7 8.2 0.44 11.6 1.1 2.0 1 1 1 2 2 2 0 Conotoxin RSN1_7TM PF02714.15 EGE01538.1 - 7.9e-77 258.2 24.4 1.3e-76 257.6 24.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EGE01538.1 - 9.1e-43 146.5 0.0 1.4e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EGE01538.1 - 6.3e-39 133.2 0.6 6.3e-39 133.2 0.6 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Bradykinin PF06753.12 EGE01538.1 - 6.5 6.6 6.1 0.42 10.4 0.2 2.1 2 0 0 2 2 2 0 Bradykinin DUF3445 PF11927.8 EGE01541.1 - 3.2e-75 252.6 0.0 4e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mid2 PF04478.12 EGE01542.1 - 0.00066 19.5 0.1 0.0015 18.4 0.1 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 EGE01542.1 - 0.15 13.0 0.0 5.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 EGE01542.1 - 1.7 8.7 9.0 0.16 12.1 2.8 2.1 1 1 1 2 2 2 0 Podoplanin SelR PF01641.18 EGE01544.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 SelR domain F-box_4 PF15966.5 EGE01546.1 - 7.1e-05 22.7 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 EGE01546.1 - 0.0013 18.5 1.5 0.0028 17.5 1.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGE01546.1 - 0.0017 18.2 0.9 0.0039 17.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like ssDBP_DBD PF18361.1 EGE01547.1 - 0.21 11.7 0.1 0.4 10.8 0.1 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain HNH_2 PF13391.6 EGE01548.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease peroxidase PF00141.23 EGE01549.1 - 1.4e-49 168.9 0.0 2.1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ERG2_Sigma1R PF04622.12 EGE01550.1 - 6.7e-80 267.3 0.1 7.7e-80 267.1 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein zf-CSL PF05207.13 EGE01551.1 - 1.2e-18 66.5 1.1 2e-18 65.9 1.1 1.4 1 1 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EGE01551.1 - 4.8e-13 49.0 0.1 4.9e-08 33.0 0.1 2.3 2 0 0 2 2 2 2 DnaJ domain PITH PF06201.13 EGE01552.1 - 3.8e-34 118.1 0.0 5.6e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EGE01552.1 - 2.1e-24 85.5 0.0 4.1e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGE01552.1 - 3.4e-05 24.1 0.0 0.00012 22.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGE01552.1 - 5.6e-05 23.5 0.1 0.00031 21.2 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGE01552.1 - 0.00063 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EGE01552.1 - 0.00071 19.7 0.1 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EGE01552.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EGE01552.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 EGE01552.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 EGE01552.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Phosducin PF02114.16 EGE01552.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosducin zf-C2H2 PF00096.26 EGE01554.1 - 2.9e-12 46.3 13.1 1.4e-06 28.4 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE01554.1 - 3.1e-07 30.7 10.7 0.0063 17.3 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE01554.1 - 1.9e-06 28.0 3.2 0.012 15.9 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGE01554.1 - 3.8e-06 27.1 3.5 3.8e-06 27.1 3.5 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGE01554.1 - 0.00045 20.1 9.0 0.02 14.9 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGE01554.1 - 0.0013 19.1 10.2 0.0081 16.5 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EGE01554.1 - 0.0053 16.6 3.5 0.19 11.6 0.5 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 EGE01554.1 - 0.015 14.9 2.8 1.3 8.8 0.4 2.8 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-UBR PF02207.20 EGE01554.1 - 0.12 12.6 0.7 0.28 11.4 0.7 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2H2_3rep PF18868.1 EGE01554.1 - 0.31 11.7 4.4 5.4 7.7 0.4 3.3 2 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 EGE01554.1 - 0.33 10.6 1.9 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 EGE01554.1 - 0.35 11.2 4.1 10 6.6 0.4 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 EGE01554.1 - 0.77 9.7 4.2 0.83 9.6 0.6 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 EGE01554.1 - 0.9 9.4 8.5 7.3 6.4 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EGE01554.1 - 2.1 8.4 5.1 1.2 9.3 1.4 2.3 1 1 1 2 2 2 0 BED zinc finger DUF629 PF04780.12 EGE01554.1 - 2.6 6.5 4.5 13 4.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Zn-ribbon_8 PF09723.10 EGE01554.1 - 2.8 8.1 4.4 6.6 6.9 0.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EGE01554.1 - 5.5 7.5 6.8 5.5e+02 1.1 7.0 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Diphthami_syn_2 PF01902.17 EGE01555.1 - 1.7e-18 66.9 0.0 3.6e-05 23.4 0.0 4.2 3 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EGE01555.1 - 4.3e-11 42.9 0.1 9.5e-06 25.6 0.0 4.0 3 1 0 3 3 3 2 Endoribonuclease L-PSP Pkinase PF00069.25 EGE01556.1 - 6.3e-11 42.1 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01556.1 - 1.5e-07 31.0 0.0 7.3e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGE01556.1 - 2.5e-07 30.9 1.5 0.00056 19.9 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE01556.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGE01556.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EGE01556.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase MFS_Mycoplasma PF07672.13 EGE01558.1 - 0.053 12.8 2.6 0.2 10.9 0.2 2.4 2 0 0 2 2 2 0 Mycoplasma MFS transporter DHHC PF01529.20 EGE01558.1 - 3.4 7.8 4.7 1.4 9.0 1.3 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cutinase PF01083.22 EGE01559.1 - 0.0032 17.5 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF3543 PF12063.8 EGE01560.1 - 3e-96 321.7 0.0 5.2e-96 320.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EGE01560.1 - 5.3e-62 209.6 0.0 9.7e-62 208.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01560.1 - 8.2e-43 146.5 0.0 2.7e-42 144.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE01560.1 - 0.053 13.4 1.0 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family AA_permease_2 PF13520.6 EGE01561.1 - 9.2e-89 298.2 34.2 1.2e-88 297.8 34.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE01561.1 - 7.3e-23 80.9 31.3 1.3e-22 80.1 31.3 1.3 1 1 0 1 1 1 1 Amino acid permease ERAP1_C PF11838.8 EGE01562.1 - 1.2e-86 291.1 0.3 1.3e-84 284.5 0.1 2.5 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGE01562.1 - 5.7e-84 281.0 2.4 9e-84 280.4 2.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGE01562.1 - 1.2e-52 178.8 1.2 2.2e-52 177.9 1.2 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EGE01562.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DEAD PF00270.29 EGE01563.1 - 3.5e-46 157.2 0.0 1.3e-45 155.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE01563.1 - 4.4e-30 104.3 0.1 2e-29 102.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE01563.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PRAI PF00697.22 EGE01563.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 EGE01563.1 - 2.4 8.8 10.0 0.13 12.8 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Neur_chan_memb PF02932.16 EGE01563.1 - 7.9 6.5 5.9 20 5.1 5.9 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0164 PF03687.13 EGE01564.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) p450 PF00067.22 EGE01565.1 - 8.9e-22 77.5 0.1 2.7e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_4 PF01565.23 EGE01566.1 - 9.9e-21 73.9 3.5 3.1e-20 72.3 3.5 1.9 1 1 0 1 1 1 1 FAD binding domain Suf PF05843.14 EGE01567.1 - 0.00046 20.3 4.3 0.00071 19.7 0.2 2.7 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGE01567.1 - 0.0082 16.9 0.4 0.0082 16.9 0.4 6.7 8 1 1 9 9 9 1 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EGE01567.1 - 0.021 15.0 1.2 3.6 7.9 0.0 3.5 2 1 0 2 2 2 0 c-SKI Smad4 binding domain ANAPC15 PF15243.6 EGE01567.1 - 0.071 13.5 0.2 0.34 11.3 0.2 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Fe_hyd_SSU PF02256.17 EGE01567.1 - 0.25 11.4 0.8 8.7 6.5 0.1 2.8 2 0 0 2 2 2 0 Iron hydrogenase small subunit Mitoc_mL59 PF18126.1 EGE01568.1 - 3.4e-49 166.4 1.8 6.2e-49 165.6 1.8 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MOSC PF03473.17 EGE01569.1 - 8.1e-30 103.5 0.0 1.4e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGE01569.1 - 1.4e-25 89.5 0.0 2.4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 EGE01569.1 - 1.1e-24 87.2 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MARVEL PF01284.23 EGE01570.1 - 0.018 15.1 10.9 0.025 14.6 10.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain Kei1 PF08552.11 EGE01570.1 - 0.019 14.9 0.0 0.025 14.5 0.0 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1980 PF09323.10 EGE01570.1 - 0.24 11.3 1.1 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SelK_SelG PF10961.8 EGE01570.1 - 0.55 10.9 3.6 0.73 10.5 0.2 2.4 2 1 0 2 2 2 0 Selenoprotein SelK_SelG Pap_E4 PF02711.14 EGE01571.1 - 1.5 9.8 5.9 2.1 9.3 5.9 1.2 1 0 0 1 1 1 0 E4 protein PAP2 PF01569.21 EGE01572.1 - 4.5e-08 33.0 1.7 8.5e-08 32.1 1.7 1.6 1 1 0 1 1 1 1 PAP2 superfamily PARM PF17061.5 EGE01573.1 - 0.086 13.0 8.1 0.12 12.5 8.1 1.1 1 0 0 1 1 1 0 PARM But2 PF09792.9 EGE01574.1 - 2.6e-47 160.8 0.1 3.3e-47 160.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Lactamase_B PF00753.27 EGE01575.1 - 0.00011 22.2 0.1 0.00024 21.1 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Cytochrom_C552 PF02335.15 EGE01575.1 - 0.081 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c552 NGP1NT PF08153.12 EGE01577.1 - 3.7e-50 169.4 0.2 5.7e-50 168.8 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGE01577.1 - 2.4e-16 59.8 0.0 1.5e-13 50.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE01577.1 - 1.7e-05 24.4 0.0 5.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGE01577.1 - 0.00074 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGE01577.1 - 0.0094 15.4 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EGE01577.1 - 0.029 14.4 0.5 0.84 9.7 0.0 3.0 3 1 1 4 4 4 0 Dynamin family Nop14 PF04147.12 EGE01577.1 - 6.8 4.8 7.8 10 4.2 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Gpr1_Fun34_YaaH PF01184.19 EGE01578.1 - 2e-49 168.0 9.6 3e-49 167.5 9.6 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YrhC PF14143.6 EGE01578.1 - 0.023 14.8 4.5 0.059 13.5 4.5 1.7 1 0 0 1 1 1 0 YrhC-like protein p450 PF00067.22 EGE01580.1 - 2.7e-70 237.4 0.0 3.3e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGE01581.1 - 3.8e-39 134.7 0.0 1.5e-38 132.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01581.1 - 4.4e-28 98.3 0.0 6.3e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01581.1 - 0.00089 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGE01581.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGE01581.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prefoldin_3 PF13758.6 EGE01582.1 - 2e-33 114.4 0.1 6.3e-33 112.8 0.1 1.9 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EGE01582.1 - 2.2e-22 79.7 1.3 2.2e-22 79.7 1.3 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3835) Lzipper-MIP1 PF14389.6 EGE01582.1 - 0.0078 16.5 0.7 11 6.4 0.0 3.8 3 0 0 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 Prefoldin_2 PF01920.20 EGE01582.1 - 0.029 14.3 0.9 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Prefoldin subunit KELK PF15796.5 EGE01582.1 - 0.31 11.5 3.9 3.2 8.3 0.2 3.6 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Zip PF02535.22 EGE01583.1 - 3.1e-39 135.1 26.1 2.6e-38 132.1 26.1 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Lactamase_B PF00753.27 EGE01583.1 - 0.27 11.2 5.5 0.12 12.4 0.5 2.6 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily MAT1 PF06391.13 EGE01584.1 - 1.2e-41 142.8 15.9 1.5e-41 142.5 15.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EGE01584.1 - 1.9e-32 110.9 8.5 3e-32 110.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE01584.1 - 0.00013 21.7 5.1 0.00024 20.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE01584.1 - 0.00016 21.5 3.7 0.00041 20.1 3.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE01584.1 - 0.0014 18.5 4.1 0.0029 17.4 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE01584.1 - 0.0017 18.7 6.2 0.0033 17.7 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EGE01584.1 - 0.011 15.5 5.1 0.069 13.0 1.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGE01584.1 - 0.017 14.7 1.4 0.034 13.8 1.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGE01584.1 - 0.029 14.3 7.2 0.23 11.4 7.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 EGE01584.1 - 0.068 13.1 2.3 0.16 11.9 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 EGE01584.1 - 0.33 11.0 6.8 0.78 9.8 6.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger MTHFR_C PF12225.8 EGE01584.1 - 0.5 10.1 2.9 2.9 7.6 2.9 2.2 1 1 0 1 1 1 0 Methylene-tetrahydrofolate reductase C terminal Prok-RING_4 PF14447.6 EGE01584.1 - 1.7 8.6 8.0 41 4.2 8.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 adh_short PF00106.25 EGE01586.1 - 1.1e-24 87.0 0.0 1.5e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE01586.1 - 6.5e-15 55.3 0.0 1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE01586.1 - 0.00046 20.1 0.1 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 KR domain DUF1263 PF06882.12 EGE01586.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) F-box-like PF12937.7 EGE01588.1 - 5.9e-05 22.9 0.1 0.00017 21.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like NHR2 PF08788.11 EGE01588.1 - 0.074 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NHR2 domain like PEX11 PF05648.14 EGE01590.1 - 4.2e-34 117.9 0.0 5.8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FMN_red PF03358.15 EGE01591.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EGE01591.1 - 0.01 16.1 0.2 0.03 14.5 0.2 1.8 1 1 0 1 1 1 0 Flavodoxin NPL4 PF05021.15 EGE01592.1 - 2e-138 460.9 0.0 2.5e-138 460.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGE01592.1 - 1.6e-68 229.4 0.1 2.6e-68 228.7 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EGE01592.1 - 0.0036 17.7 0.0 0.014 15.9 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Kinesin PF00225.23 EGE01593.1 - 1.2e-116 389.3 0.1 2e-116 388.6 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGE01593.1 - 1.3e-26 93.4 1.4 2e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Herpes_UL14 PF03580.14 EGE01593.1 - 0.0037 17.5 1.7 0.013 15.8 1.7 1.9 1 0 0 1 1 1 1 Herpesvirus UL14-like protein ArgoL2 PF16488.5 EGE01593.1 - 0.12 12.7 0.3 0.33 11.3 0.3 1.8 1 0 0 1 1 1 0 Argonaute linker 2 domain ING PF12998.7 EGE01593.1 - 3.2 8.4 8.0 3 8.5 2.4 3.1 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF5565 PF17720.1 EGE01594.1 - 0.071 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) Tim17 PF02466.19 EGE01595.1 - 0.0002 21.7 2.9 0.00027 21.3 2.2 1.5 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Dsh_C PF12316.8 EGE01598.1 - 4.4 7.6 9.0 1.3 9.4 0.4 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal cNMPbd_u2 PF16643.5 EGE01599.1 - 6.2e-38 130.7 8.9 6.2e-38 130.7 8.9 2.7 3 0 0 3 3 3 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 EGE01599.1 - 8.3e-35 118.7 0.0 1.5e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EGE01599.1 - 1.1e-09 37.6 9.0 1.6 9.0 0.0 8.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 EGE01599.1 - 1.9e-05 24.9 7.3 0.043 14.3 0.1 6.0 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGE01599.1 - 5.4e-05 23.0 1.4 0.00011 22.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGE01599.1 - 0.0018 18.1 7.0 0.0021 17.9 0.7 3.4 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 EGE01599.1 - 0.008 16.6 10.4 61 4.7 0.1 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 EGE01599.1 - 0.12 12.7 3.4 9.8 6.5 0.5 3.9 3 2 0 3 3 3 0 Ste50p, sterile alpha motif Zn_clus PF00172.18 EGE01600.1 - 1.1e-07 31.8 7.8 1.9e-07 31.1 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YabA PF06156.13 EGE01600.1 - 0.013 16.1 0.5 0.052 14.2 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EGE01600.1 - 0.016 15.7 0.7 0.016 15.7 0.7 2.8 3 1 0 3 3 3 0 Cell division protein ZapB NRBF2 PF08961.10 EGE01600.1 - 0.035 13.7 0.2 0.035 13.7 0.2 2.8 4 0 0 4 4 4 0 Nuclear receptor-binding factor 2, autophagy regulator RasGAP_C PF03836.15 EGE01600.1 - 0.086 13.0 3.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus TSC22 PF01166.18 EGE01600.1 - 1.7 9.0 3.8 0.51 10.7 0.2 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family PikAIV_N PF18605.1 EGE01600.1 - 4.3 7.0 10.7 1.5 8.5 1.1 2.4 1 1 1 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Slx4 PF09494.10 EGE01601.1 - 4e-25 87.5 0.3 9.7e-25 86.3 0.3 1.6 2 0 0 2 2 2 1 Slx4 endonuclease CGI-121 PF08617.10 EGE01602.1 - 5.8e-59 198.8 0.5 6.7e-59 198.6 0.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.20 EGE01603.1 - 6.7e-33 114.3 10.3 6.7e-33 114.3 10.3 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Cutinase PF01083.22 EGE01605.1 - 3.5e-37 128.1 0.0 5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 EGE01605.1 - 0.00066 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 EGE01605.1 - 0.069 12.7 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 EGE01605.1 - 0.21 11.2 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold RRM_1 PF00076.22 EGE01606.1 - 1e-15 57.3 0.0 1.5e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE01606.1 - 0.0061 16.1 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shadoo PF14999.6 EGE01606.1 - 8.9 6.4 10.2 14 5.8 7.7 2.0 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Glyco_hydro_76 PF03663.14 EGE01607.1 - 4.3e-24 85.7 0.1 5.6e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGE01607.1 - 0.045 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DUF2236 PF09995.9 EGE01608.1 - 1.2e-06 28.9 0.1 3e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2205 PF10224.9 EGE01613.1 - 6.5e-33 112.6 0.4 1.1e-32 111.8 0.4 1.4 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 EGE01613.1 - 0.018 15.6 0.3 0.031 14.9 0.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF4208 PF13907.6 EGE01613.1 - 0.023 15.1 0.1 0.037 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DivIC PF04977.15 EGE01613.1 - 0.029 14.1 0.4 0.047 13.5 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4201 PF13870.6 EGE01613.1 - 0.029 14.1 0.4 0.041 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) HALZ PF02183.18 EGE01613.1 - 0.042 14.1 2.7 0.1 12.8 0.2 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 EGE01613.1 - 0.052 13.1 0.2 0.068 12.8 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Prefoldin PF02996.17 EGE01613.1 - 0.079 12.9 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Prefoldin subunit CASP_C PF08172.12 EGE01613.1 - 0.13 11.6 8.3 0.042 13.2 0.9 2.1 2 0 0 2 2 2 0 CASP C terminal NAM-associated PF14303.6 EGE01613.1 - 3.5 8.3 9.0 8.9 7.0 9.0 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain 14-3-3 PF00244.20 EGE01616.1 - 9.8e-105 349.0 7.3 1.2e-104 348.7 7.3 1.1 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 EGE01617.1 - 2.1e-26 92.2 2.0 2.4e-26 92.0 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Pannexin_like PF12534.8 EGE01617.1 - 0.13 11.3 0.2 0.13 11.3 0.2 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Nsp1_C PF05064.13 EGE01618.1 - 6.6e-43 145.2 3.4 1.5e-42 144.1 3.4 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EGE01618.1 - 0.0026 18.6 143.1 0.069 14.0 27.9 7.0 1 1 1 2 2 1 1 Nucleoporin FG repeat region ParB PF08775.10 EGE01618.1 - 0.037 14.5 0.4 0.037 14.5 0.4 1.9 2 1 0 2 2 2 0 ParB family HIP1_clath_bdg PF16515.5 EGE01618.1 - 0.15 12.7 14.1 1.5 9.5 6.0 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2935 PF11155.8 EGE01618.1 - 0.29 11.5 1.1 3 8.2 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4200 PF13863.6 EGE01618.1 - 0.47 10.9 11.9 0.22 11.9 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 EGE01618.1 - 0.53 10.6 12.5 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 EGE01618.1 - 0.56 10.6 9.1 0.97 9.9 0.4 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 EGE01618.1 - 0.7 9.2 9.0 1.3 8.3 9.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EGE01618.1 - 0.89 9.6 8.8 1.8 8.6 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EGE01618.1 - 1 7.9 7.9 2 7.0 7.5 1.5 1 1 0 1 1 1 0 AAA domain Med21 PF11221.8 EGE01618.1 - 1.1 9.5 12.7 30 4.9 12.7 2.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Baculo_PEP_C PF04513.12 EGE01618.1 - 1.2 9.2 7.2 1.7 8.7 5.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 EGE01618.1 - 1.6 7.6 10.7 0.15 11.0 3.9 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 EGE01618.1 - 2.6 8.1 10.4 4.5 7.3 3.1 2.4 1 1 2 3 3 3 0 Laminin Domain II CK2S PF15011.6 EGE01618.1 - 2.8 7.8 7.7 1.9 8.4 3.4 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate FliT PF05400.13 EGE01618.1 - 2.9 8.8 6.0 14 6.6 4.5 2.6 1 1 0 1 1 1 0 Flagellar protein FliT CREPT PF16566.5 EGE01618.1 - 5 7.3 7.0 1.1 9.4 1.7 2.1 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour V-SNARE PF05008.15 EGE01618.1 - 5.1 7.5 9.5 1.1 9.6 0.7 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Occludin_ELL PF07303.13 EGE01618.1 - 6.4 7.6 5.3 7.3 7.4 1.9 2.2 2 0 0 2 2 2 0 Occludin homology domain BRE1 PF08647.11 EGE01618.1 - 7.7 6.7 9.3 11 6.2 4.8 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 EGE01618.1 - 7.7 5.3 14.7 2.1 7.2 7.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GAT PF03127.14 EGE01618.1 - 8.5 6.8 7.0 13 6.2 0.2 2.8 1 1 1 2 2 2 0 GAT domain DUF5102 PF17104.5 EGE01619.1 - 3e-115 385.2 1.8 3e-115 385.2 1.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) zf-MIZ PF02891.20 EGE01620.1 - 1.3e-10 40.9 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF281 PF03436.13 EGE01620.1 - 0.39 11.2 0.0 0.39 11.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF281) PH PF00169.29 EGE01621.1 - 2.4e-10 40.8 0.3 3.9e-09 36.9 0.3 2.7 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 EGE01621.1 - 1.2e-09 37.6 0.0 2.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE01621.1 - 5.7e-09 35.7 0.2 1.2e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EGE01621.1 - 2.6e-08 33.9 0.1 5.3e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EGE01621.1 - 0.00023 20.8 0.1 0.00045 19.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EGE01621.1 - 0.00064 20.1 0.0 0.0025 18.2 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 EGE01621.1 - 0.0023 18.3 0.1 0.0044 17.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EGE01621.1 - 0.033 14.5 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Gastrin PF00918.17 EGE01621.1 - 0.17 12.8 2.1 0.66 10.9 0.1 3.1 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Ribosomal_L14 PF00238.19 EGE01623.1 - 3.7e-33 114.2 0.0 4e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 EGE01623.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 EGE01624.1 - 2.6e-75 253.8 0.0 5.9e-75 252.6 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EGE01625.1 - 1.1e-33 115.7 0.0 2.5e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGE01625.1 - 4.8e-12 46.3 0.8 7.6e-12 45.6 0.8 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGE01625.1 - 6.4e-08 32.4 0.0 4.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NIF PF03031.18 EGE01627.1 - 1.2e-40 138.9 0.0 1.7e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Fungal_trans PF04082.18 EGE01629.1 - 1.4e-16 60.4 0.0 3.5e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01629.1 - 1.8e-06 28.0 6.3 3.4e-06 27.1 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EGE01631.1 - 1.9e-05 24.4 1.2 4.7e-05 23.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EGE01631.1 - 0.0048 17.7 0.1 9.6 7.3 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat F-box PF00646.33 EGE01631.1 - 0.005 16.7 1.4 0.011 15.6 1.4 1.6 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 EGE01632.1 - 4.2e-08 32.6 0.7 7.3e-08 31.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EGE01634.1 - 1.1e-34 120.0 2.2 1.2e-25 90.3 1.5 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01634.1 - 2.8e-18 66.1 1.6 2e-17 63.4 1.6 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2501 PF10696.9 EGE01634.1 - 4.4 7.7 6.1 25 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2501) MFS_1 PF07690.16 EGE01635.1 - 2.2e-30 105.8 35.5 3.6e-22 78.8 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01635.1 - 1e-20 74.1 12.1 4.1e-20 72.1 12.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE01637.1 - 1.1e-27 96.9 38.4 1.1e-27 96.9 38.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01637.1 - 2.5e-09 36.5 32.0 3.5e-06 26.2 11.9 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter M20_dimer PF07687.14 EGE01639.1 - 0.94 9.4 6.1 3.4 7.6 0.3 3.1 4 0 0 4 4 4 0 Peptidase dimerisation domain HAMP PF00672.25 EGE01640.1 - 2.4e-36 123.9 15.9 6.6e-08 32.8 0.5 7.9 6 2 2 8 8 8 5 HAMP domain HATPase_c PF02518.26 EGE01640.1 - 2.9e-33 114.7 0.0 1.5e-32 112.4 0.0 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGE01640.1 - 1.1e-24 86.8 1.2 6e-24 84.4 0.5 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGE01640.1 - 6.8e-17 61.3 4.1 2.2e-16 59.6 0.1 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 EGE01640.1 - 9.6e-06 25.8 0.0 3.5 7.9 0.0 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF4279) DUF3829 PF12889.7 EGE01640.1 - 0.00095 18.7 13.9 0.037 13.5 0.2 5.0 5 1 1 6 6 6 2 Protein of unknown function (DUF3829) DUF948 PF06103.11 EGE01640.1 - 0.0017 18.6 47.8 1.3 9.3 0.1 9.1 3 1 2 5 5 4 1 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EGE01640.1 - 0.0017 18.7 15.2 5.6 7.4 0.0 6.8 3 2 3 7 7 7 1 Syntaxin-like protein Fib_alpha PF08702.10 EGE01640.1 - 0.019 15.1 34.0 2.7 8.2 0.1 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family NOD PF06816.13 EGE01640.1 - 0.048 13.3 0.0 6 6.6 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein IcmF_C PF06744.12 EGE01640.1 - 0.059 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal Vps52 PF04129.12 EGE01640.1 - 0.064 12.0 4.4 4.8 5.8 0.2 3.8 4 0 0 4 4 4 0 Vps52 / Sac2 family SpoIIID PF12116.8 EGE01640.1 - 0.11 12.7 2.8 25 5.1 0.1 4.5 4 0 0 4 4 4 0 Stage III sporulation protein D Gp-FAR-1 PF05823.12 EGE01640.1 - 0.11 12.9 4.4 36 4.7 0.0 4.7 1 1 4 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) WXG100 PF06013.12 EGE01640.1 - 0.42 10.9 19.5 11 6.3 0.2 7.1 6 2 1 7 7 7 0 Proteins of 100 residues with WXG CMD PF02627.20 EGE01640.1 - 0.58 10.2 2.2 8.6 6.5 0.1 3.7 4 0 0 4 4 4 0 Carboxymuconolactone decarboxylase family DUF2877 PF11392.8 EGE01640.1 - 1.2 9.9 9.0 11 6.8 0.2 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2877) CENP-F_leu_zip PF10473.9 EGE01640.1 - 2 8.5 27.6 3.5 7.6 0.2 7.5 5 3 3 8 8 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GhoS PF11080.8 EGE01640.1 - 3.6 7.6 7.4 4.3 7.4 0.1 3.9 4 0 0 4 4 4 0 Endoribonuclease GhoS GLE1 PF07817.13 EGE01640.1 - 3.6 6.7 11.3 20 4.3 0.4 4.3 3 1 2 5 5 5 0 GLE1-like protein AdHead_fibreRBD PF16812.5 EGE01640.1 - 3.7 7.3 11.8 0.046 13.5 0.4 3.3 4 0 0 4 4 4 0 C-terminal head domain of the fowl adenovirus type 1 long fibre tRNA-synt_2d PF01409.20 EGE01641.1 - 2.3e-88 295.8 0.0 3.1e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGE01641.1 - 1.3e-16 60.6 0.5 1.3e-16 60.6 0.5 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA-synt_2 PF00152.20 EGE01641.1 - 6.1e-05 22.3 0.1 0.0033 16.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 EGE01641.1 - 7e-05 22.4 0.0 0.043 13.3 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EGE01641.1 - 0.0015 18.5 0.3 0.0039 17.1 0.3 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 DUF2564 PF10819.8 EGE01641.1 - 0.012 15.9 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Ribosomal_S21e PF01249.18 EGE01642.1 - 1.3e-30 105.3 0.3 3e-30 104.2 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S21e Scm3 PF10384.9 EGE01642.1 - 0.084 12.6 0.1 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Centromere protein Scm3 NUDIX PF00293.28 EGE01643.1 - 9.3e-07 28.9 0.0 3.8e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 EGE01644.1 - 5.7e-130 433.3 5.2 6.8e-130 433.1 5.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGE01644.1 - 1e-18 67.5 0.1 1.4e-09 38.3 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EGE01644.1 - 7.9e-08 31.7 0.7 2e-07 30.4 0.7 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EGE01644.1 - 4.1e-06 26.4 9.1 0.0025 17.3 6.3 3.0 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 EGE01644.1 - 9.5e-05 22.0 2.3 0.0003 20.3 2.3 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.21 EGE01644.1 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Aldolase PF01081.19 EGE01644.1 - 0.012 15.1 1.7 0.067 12.6 0.2 2.4 1 1 0 2 2 2 0 KDPG and KHG aldolase ThiG PF05690.14 EGE01644.1 - 0.031 13.6 0.5 0.031 13.6 0.5 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG YpsA PF06908.11 EGE01644.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Glu_synthase PF01645.17 EGE01644.1 - 0.053 12.7 3.3 0.094 11.8 3.3 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase EAL PF00563.20 EGE01644.1 - 0.16 11.5 0.5 17 4.8 0.0 2.5 2 1 0 2 2 2 0 EAL domain G3P_antiterm PF04309.12 EGE01644.1 - 0.28 10.6 2.0 2.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator RasGAP PF00616.19 EGE01645.1 - 5.6e-52 176.5 0.0 1.2e-51 175.4 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGE01645.1 - 2e-50 170.5 4.7 7.6e-50 168.6 4.7 2.2 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 EGE01645.1 - 9.4e-10 37.4 43.1 0.21 11.4 0.0 15.1 16 1 1 17 17 17 4 IQ calmodulin-binding motif CH PF00307.31 EGE01645.1 - 4.6e-08 33.2 0.0 3.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF1033 PF06279.11 EGE01645.1 - 0.061 13.5 0.4 0.7 10.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) CAMSAP_CH PF11971.8 EGE01645.1 - 0.062 13.1 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain IZUMO PF15005.6 EGE01645.1 - 0.074 13.6 0.1 0.37 11.3 0.1 2.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Trypan_PARP PF05887.11 EGE01645.1 - 0.35 10.8 4.1 0.76 9.8 4.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MbeB_N PF04837.12 EGE01645.1 - 9.5 6.6 6.3 53 4.2 0.2 3.7 3 0 0 3 3 3 0 MbeB-like, N-term conserved region ENTH PF01417.20 EGE01646.1 - 5e-46 155.8 0.1 7.9e-46 155.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGE01646.1 - 0.00038 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.28 EGE01647.1 - 3.2e-11 42.6 0.0 5.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE01647.1 - 6.4e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGE01647.1 - 4.2e-07 29.6 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 EGE01648.1 - 7.2e-26 90.9 50.3 9.3e-15 54.4 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGE01648.1 - 9.2e-07 27.8 13.3 9.2e-07 27.8 13.3 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGE01648.1 - 9.6e-06 24.7 25.5 3e-05 23.1 10.2 2.1 1 1 1 2 2 2 2 MFS_1 like family 7TM_GPCR_Srh PF10318.9 EGE01648.1 - 3.8e-05 22.9 1.4 3.8e-05 22.9 1.4 2.9 4 1 0 4 4 4 1 Serpentine type 7TM GPCR chemoreceptor Srh HMG-CoA_red PF00368.18 EGE01651.1 - 2.9e-136 454.3 10.6 2.9e-136 454.3 10.6 1.4 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EGE01651.1 - 6.2e-45 152.8 0.0 1.1e-44 152.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EGE01651.1 - 8.8e-13 48.4 4.8 1.1e-11 44.8 4.8 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EGE01651.1 - 1.8e-05 23.1 2.4 1.8e-05 23.1 2.4 1.3 2 0 0 2 2 2 1 Patched family CVNH PF08881.10 EGE01652.1 - 1.2e-23 83.7 0.5 1.9e-23 83.1 0.5 1.3 1 0 0 1 1 1 1 CVNH domain Protamine_P2 PF00841.19 EGE01653.1 - 9 6.9 22.7 0.24 11.9 14.8 1.9 1 1 1 2 2 2 0 Sperm histone P2 GIT_SHD PF08518.11 EGE01654.1 - 4e-22 77.5 10.1 1.8e-11 43.5 1.2 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3450 PF11932.8 EGE01654.1 - 1.6 8.0 24.0 0.85 8.9 1.7 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 EGE01654.1 - 2.4 5.6 33.0 0.2 9.1 10.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) GAS PF13851.6 EGE01654.1 - 5.8 6.2 29.7 3.2 7.1 1.1 2.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding RNase_PH PF01138.21 EGE01655.1 - 4.8e-33 114.5 0.2 9.2e-33 113.6 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 EGE01656.1 - 3.1e-52 177.4 0.0 5.2e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EGE01656.1 - 5.5e-25 87.3 0.4 1.6e-24 85.8 0.4 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EGE01656.1 - 3e-19 69.4 0.0 1.1e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGE01656.1 - 1.9e-08 33.8 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGE01656.1 - 4e-08 33.4 0.2 1.9e-07 31.2 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE01656.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1018 PF06252.12 EGE01656.1 - 0.028 15.4 0.1 0.098 13.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Ssu72 PF04722.13 EGE01657.1 - 3.8e-82 274.5 0.0 4.4e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PRIMA1 PF16101.5 EGE01657.1 - 1.2 9.2 8.7 2.1 8.4 8.7 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EGE01657.1 - 2 8.4 4.4 2.8 8.0 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 EGE01657.1 - 4.6 6.8 6.5 6.6 6.2 6.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal zf-CHCC PF10276.9 EGE01658.1 - 0.003 17.6 3.9 0.059 13.4 0.3 2.9 2 0 0 2 2 2 1 Zinc-finger domain PyrI_C PF02748.15 EGE01658.1 - 0.049 13.5 0.4 8.7 6.3 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC PF00098.23 EGE01658.1 - 0.05 13.7 3.3 0.1 12.7 3.3 1.6 1 0 0 1 1 1 0 Zinc knuckle RAP1 PF07218.11 EGE01658.1 - 0.2 9.9 4.6 0.3 9.3 4.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-BED PF02892.15 EGE01658.1 - 0.55 10.3 3.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger ATP-synt_G PF04718.15 EGE01658.1 - 0.97 10.3 3.0 1.4 9.8 1.1 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit Trypan_PARP PF05887.11 EGE01658.1 - 2.8 7.9 11.5 12 5.8 6.0 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Acyl-CoA_dh_1 PF00441.24 EGE01659.1 - 8.2e-18 65.0 0.1 4.9e-17 62.5 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EGE01659.1 - 8.6e-13 48.5 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EGE01659.1 - 7.7e-10 38.8 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Oxysterol_BP PF01237.18 EGE01660.1 - 5.3e-88 295.4 0.1 1e-77 261.5 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3605 PF12239.8 EGE01661.1 - 4.6e-52 176.4 1.7 6.3e-52 176.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF4116 PF13475.6 EGE01661.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Isochorismatase PF00857.20 EGE01662.1 - 2.2e-26 93.1 0.0 3.9e-25 89.0 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Hist_deacetyl PF00850.19 EGE01663.1 - 8.7e-78 261.9 0.0 1.3e-77 261.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EGE01664.1 - 1.7e-22 79.9 3.6 2.8e-22 79.2 3.6 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGE01664.1 - 2.7e-05 24.0 9.7 5.1e-05 23.1 9.7 1.5 1 0 0 1 1 1 1 PHD-finger TFIIA PF03153.13 EGE01664.1 - 0.011 15.8 7.1 0.016 15.2 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-HC5HC2H PF13771.6 EGE01664.1 - 0.046 14.0 0.3 0.11 12.8 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prominin PF05478.11 EGE01664.1 - 0.085 10.8 0.6 0.13 10.2 0.3 1.4 2 0 0 2 2 2 0 Prominin PHD_2 PF13831.6 EGE01664.1 - 0.54 9.9 3.8 1.1 8.8 3.8 1.5 1 0 0 1 1 1 0 PHD-finger Hamartin PF04388.12 EGE01664.1 - 2.9 6.4 11.5 4.3 5.9 11.5 1.2 1 0 0 1 1 1 0 Hamartin protein RNA_pol_Rpc34 PF05158.12 EGE01665.1 - 1.6e-105 353.3 0.0 1.9e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EGE01665.1 - 0.19 12.1 0.1 0.89 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator STI1 PF17830.1 EGE01666.1 - 2e-36 123.7 7.3 4.7e-20 71.3 0.6 2.9 2 0 0 2 2 2 2 STI1 domain TPR_1 PF00515.28 EGE01666.1 - 1.1e-35 120.0 22.9 2.1e-05 24.1 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGE01666.1 - 1.7e-25 87.0 23.6 0.00025 20.9 0.1 9.9 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGE01666.1 - 2.2e-15 56.0 16.6 0.0079 15.9 0.5 8.0 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.6 EGE01666.1 - 7.5e-14 50.7 20.6 0.01 16.0 0.1 8.5 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGE01666.1 - 8.6e-11 42.2 22.0 0.002 18.6 0.3 6.7 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGE01666.1 - 1.2e-09 38.2 3.0 0.0018 18.4 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE01666.1 - 6.6e-09 35.9 18.6 0.00019 21.6 0.2 6.0 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE01666.1 - 2.9e-08 34.2 12.1 0.12 13.1 1.1 5.9 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGE01666.1 - 1.2e-07 31.7 8.8 0.11 12.9 0.0 6.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE01666.1 - 2.7e-07 30.1 10.7 0.0071 16.3 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE01666.1 - 4.7e-06 27.0 22.1 1.6 9.7 0.2 8.9 8 2 2 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE01666.1 - 0.00028 21.0 7.7 0.24 11.7 0.2 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGE01666.1 - 0.00044 20.0 10.7 0.31 11.0 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE01666.1 - 0.019 15.5 17.3 1.3 9.8 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.16 EGE01666.1 - 0.054 14.2 0.0 0.25 12.0 0.0 2.2 1 0 0 1 1 1 0 Peptidase inhibitor I9 SPESP1 PF15754.5 EGE01666.1 - 0.52 9.4 4.3 0.14 11.3 0.7 1.8 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 SHNi-TPR PF10516.9 EGE01666.1 - 0.79 9.2 7.3 20 4.8 0.1 5.4 6 0 0 6 6 6 0 SHNi-TPR DUF627 PF04781.12 EGE01666.1 - 0.88 9.6 6.0 2.7 8.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Trypan_PARP PF05887.11 EGE01666.1 - 9.6 6.2 19.3 0.17 11.8 9.1 2.8 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) C2 PF00168.30 EGE01667.1 - 7.9e-73 241.3 0.4 4.6e-19 68.6 0.0 6.0 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 EGE01667.1 - 0.0071 15.8 0.1 0.056 12.9 0.0 2.4 2 1 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain RRM_1 PF00076.22 EGE01668.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGE01668.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 S-antigen PF05756.11 EGE01668.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 S-antigen protein SR-25 PF10500.9 EGE01669.1 - 0.003 17.2 11.3 0.0032 17.1 11.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AP3D1 PF06375.11 EGE01669.1 - 0.026 14.8 8.6 0.03 14.6 8.6 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 BRF1 PF07741.13 EGE01669.1 - 0.8 10.1 11.3 0.99 9.8 11.3 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Presenilin PF01080.17 EGE01669.1 - 1.2 7.8 2.6 1.2 7.8 2.6 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EGE01669.1 - 5.7 7.0 8.3 7.1 6.7 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UDPGP PF01704.18 EGE01670.1 - 2.8e-189 629.0 0.0 3.3e-189 628.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EGE01670.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilO RRM_1 PF00076.22 EGE01672.1 - 0.00029 20.6 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EGE01672.1 - 0.63 10.0 9.8 0.11 12.4 4.8 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SCRG1 PF15224.6 EGE01672.1 - 2 8.6 6.2 0.53 10.4 0.2 2.3 2 1 0 2 2 2 0 Scrapie-responsive protein 1 DUF4185 PF13810.6 EGE01673.1 - 0.00039 19.8 0.1 0.00055 19.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Amidase PF01425.21 EGE01674.1 - 1e-86 291.7 0.0 3.1e-86 290.1 0.0 1.6 1 1 0 1 1 1 1 Amidase SepZ PF06066.11 EGE01674.1 - 0.069 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 SepZ MFS_1 PF07690.16 EGE01675.1 - 4.3e-12 45.6 20.0 6.5e-12 45.0 17.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily PhyH PF05721.13 EGE01676.1 - 9.7e-30 104.4 0.0 1.3e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HNH_2 PF13391.6 EGE01677.1 - 4.5e-09 36.3 0.1 9.5e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Epimerase PF01370.21 EGE01678.1 - 8.6e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 EGE01679.1 - 1.7e-05 24.8 12.1 3e-05 24.0 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE01679.1 - 0.0011 18.1 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE PF01363.21 EGE01680.1 - 1.1e-19 70.3 2.0 1.1e-19 70.3 2.0 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EGE01680.1 - 3.8e-06 27.1 8.0 3.8e-06 27.1 8.0 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 EGE01680.1 - 0.0002 21.1 4.9 0.0002 21.1 4.9 3.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGE01680.1 - 0.0003 20.6 7.1 0.0003 20.6 7.1 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE01680.1 - 0.014 15.6 6.7 0.014 15.6 6.7 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain Zn-C2H2_12 PF18112.1 EGE01680.1 - 0.049 14.1 7.2 0.68 10.5 1.2 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain FYVE_2 PF02318.16 EGE01680.1 - 2.7 8.2 9.5 0.13 12.5 0.7 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger TRP PF06011.12 EGE01681.1 - 4.5e-40 137.7 20.4 6.1e-38 130.7 20.4 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGE01681.1 - 1.2e-15 58.1 0.1 1.9e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF4381 PF14316.6 EGE01681.1 - 4.2 7.6 7.1 12 6.1 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Strabismus PF06638.11 EGE01681.1 - 6.7 5.2 6.3 10 4.6 6.3 1.1 1 0 0 1 1 1 0 Strabismus protein Cys_Met_Meta_PP PF01053.20 EGE01683.1 - 3.2e-61 207.0 0.0 1.4e-60 204.9 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGE01683.1 - 0.0014 17.7 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF2073 PF09846.9 EGE01683.1 - 0.0095 15.8 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2073) Aminotran_1_2 PF00155.21 EGE01683.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II ThiS PF02597.20 EGE01684.1 - 0.0009 19.8 0.0 0.0084 16.7 0.0 1.9 1 1 0 1 1 1 1 ThiS family GFA PF04828.14 EGE01685.1 - 2.3e-23 82.3 0.6 2.3e-23 82.3 0.6 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme INPP5B_PH PF16776.5 EGE01685.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Zn_clus PF00172.18 EGE01686.1 - 1.9e-08 34.3 4.5 3.6e-08 33.4 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE01686.1 - 2.3e-06 26.9 0.0 5.2e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 EGE01687.1 - 7.5e-30 103.9 28.8 1e-29 103.5 28.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGE01687.1 - 6.5e-26 91.5 0.3 2e-25 89.9 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGE01687.1 - 1.7e-07 31.4 0.2 0.0082 16.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGE01687.1 - 8.2e-06 25.8 0.2 4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EGE01687.1 - 4.4e-05 23.0 0.1 0.00011 21.8 0.1 1.6 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGE01687.1 - 0.00021 21.7 0.3 0.00064 20.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGE01687.1 - 0.0022 18.4 0.0 0.034 14.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGE01687.1 - 0.0024 17.5 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGE01687.1 - 0.0035 16.5 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 EGE01687.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGE01687.1 - 0.006 16.9 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGE01687.1 - 0.0083 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EGE01687.1 - 0.0096 15.1 25.0 0.016 14.4 25.0 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_13 PF13166.6 EGE01687.1 - 0.011 14.4 4.5 0.012 14.3 0.1 2.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EGE01687.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGE01687.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGE01687.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGE01687.1 - 0.015 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGE01687.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE01687.1 - 0.031 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGE01687.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EGE01687.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EGE01687.1 - 0.072 13.6 0.9 0.24 11.9 0.2 2.0 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGE01687.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGE01687.1 - 0.089 13.2 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 EGE01687.1 - 0.16 12.1 0.3 0.44 10.6 0.1 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase tRNA-synt_2 PF00152.20 EGE01688.1 - 9.9e-88 294.2 0.0 1.3e-87 293.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE01688.1 - 4.7e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 EGE01688.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EGE01688.1 - 0.17 11.3 0.0 0.51 9.8 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) LRRCT PF01463.24 EGE01689.1 - 0.26 11.9 1.7 8.5 7.2 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat C-terminal domain PUD PF03714.14 EGE01690.1 - 0.066 14.1 0.7 15 6.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain Oxidored_q2 PF00420.24 EGE01690.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PEP_mutase PF13714.6 EGE01691.1 - 7e-67 225.4 1.1 7.9e-67 225.2 1.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ABC_tran PF00005.27 EGE01692.1 - 6.4e-49 166.0 0.0 1.9e-31 109.4 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE01692.1 - 2.7e-39 135.5 30.3 1.8e-25 90.2 9.8 3.5 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGE01692.1 - 5.6e-12 45.6 0.0 0.0062 16.0 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGE01692.1 - 8.9e-08 32.9 0.5 4.3e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE01692.1 - 6.4e-06 26.5 0.1 1.5 9.1 0.0 4.3 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 EGE01692.1 - 0.00031 20.7 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGE01692.1 - 0.00036 20.6 0.2 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGE01692.1 - 0.0004 20.1 3.8 0.075 12.8 0.2 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 EGE01692.1 - 0.0005 19.2 0.0 0.054 12.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 EGE01692.1 - 0.00071 20.0 0.2 1.4 9.3 0.0 3.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGE01692.1 - 0.0038 17.1 0.2 9.2 6.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EGE01692.1 - 0.0069 16.1 0.3 0.7 9.6 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGE01692.1 - 0.016 14.5 0.1 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 EGE01692.1 - 0.024 14.7 4.9 0.86 9.7 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 EGE01692.1 - 0.059 13.1 0.1 5.8 6.5 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 EGE01692.1 - 0.095 11.9 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 EGE01692.1 - 0.096 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGE01692.1 - 0.098 12.4 0.5 21 4.8 0.1 3.0 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 EGE01692.1 - 0.2 11.7 0.7 28 4.8 0.5 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoD PF09423.10 EGE01693.1 - 1.3e-111 373.0 1.0 1.6e-111 372.7 1.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EGE01693.1 - 8.5e-20 71.1 0.0 2.2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EGE01693.1 - 0.00018 22.0 0.7 0.0005 20.6 0.7 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain LigD_N PF13298.6 EGE01694.1 - 3.2e-35 120.6 0.1 5.7e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Sulf_transp PF04143.14 EGE01695.1 - 1.1e-06 28.5 17.5 2.3e-05 24.1 3.5 3.3 3 0 0 3 3 3 3 Sulphur transport Peptidase_M28 PF04389.17 EGE01696.1 - 1.3e-29 103.4 0.0 2.4e-29 102.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Rhodanese PF00581.20 EGE01699.1 - 1.8e-07 31.7 0.0 2.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HTH_22 PF13309.6 EGE01699.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH domain MutS_V PF00488.21 EGE01700.1 - 9.8e-67 224.6 0.1 1.8e-66 223.8 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE01700.1 - 1.8e-42 145.7 0.1 4.1e-42 144.6 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EGE01700.1 - 3.8e-33 114.1 0.1 1.7e-32 112.0 0.1 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EGE01700.1 - 1.7e-15 57.1 2.4 4e-15 55.9 2.4 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGE01700.1 - 2.7e-13 50.4 0.0 9.4e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II SPT6_acidic PF14632.6 EGE01700.1 - 0.0055 17.3 9.4 0.0055 17.3 9.4 3.3 3 1 1 4 4 2 1 Acidic N-terminal SPT6 AAA_27 PF13514.6 EGE01700.1 - 0.018 14.6 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGE01700.1 - 0.025 15.1 0.1 0.025 15.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGE01700.1 - 0.068 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EGE01700.1 - 0.56 10.0 4.2 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Spem1 PF15670.5 EGE01700.1 - 2.4 7.7 6.2 4.9 6.6 6.2 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 tRNA-synt_1b PF00579.25 EGE01701.1 - 1.7e-72 244.2 0.0 2.3e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EGE01701.1 - 9e-44 148.1 0.0 1.8e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Raffinose_syn PF05691.12 EGE01702.1 - 6.8e-17 60.6 2.0 2.1e-13 49.0 1.7 3.2 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 EGE01702.1 - 0.0018 17.3 0.2 0.0028 16.7 0.2 1.2 1 0 0 1 1 1 1 Melibiase DUF1697 PF08002.11 EGE01702.1 - 0.091 13.2 0.2 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Aldedh PF00171.22 EGE01703.1 - 5.6e-165 549.3 0.4 6.4e-165 549.1 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRN9 PF10680.9 EGE01704.1 - 3e-23 81.9 0.7 8.5e-23 80.4 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 EGE01704.1 - 0.13 12.8 0.1 0.33 11.5 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pescadillo_N PF06732.11 EGE01705.1 - 1.6e-123 411.6 0.0 1.6e-123 411.6 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGE01705.1 - 0.0019 18.6 0.0 0.0089 16.4 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGE01705.1 - 0.043 14.2 0.0 0.55 10.6 0.0 2.7 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.13 EGE01706.1 - 2.8e-70 237.3 13.4 3e-70 237.2 13.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 EGE01706.1 - 0.0069 16.3 2.1 0.012 15.5 0.2 1.9 1 1 0 2 2 2 1 Mannosyltransferase (PIG-M) Acetyltransf_1 PF00583.25 EGE01707.1 - 1.9e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE01707.1 - 1.9e-09 37.5 0.0 5.5e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE01707.1 - 6.3e-09 36.1 0.0 9.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE01707.1 - 2.8e-05 24.0 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGE01707.1 - 0.0039 17.3 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGE01707.1 - 0.022 15.4 0.0 0.032 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.15 EGE01708.1 - 9.8e-15 54.4 0.1 1.4e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EGE01708.1 - 0.00088 19.8 0.0 0.0012 19.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EGE01708.1 - 0.013 16.2 0.0 0.019 15.7 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like HIG_1_N PF04588.13 EGE01709.1 - 7.8e-30 102.9 0.6 1.1e-29 102.4 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PALP PF00291.25 EGE01710.1 - 2.1e-78 263.7 0.4 2.6e-78 263.4 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGE01710.1 - 9.5e-42 140.7 0.0 1.8e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GTP_EFTU PF00009.27 EGE01712.1 - 2.2e-58 197.0 0.4 4e-58 196.2 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGE01712.1 - 9.8e-34 115.7 0.0 2.1e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGE01712.1 - 2.7e-32 110.7 0.0 5.5e-32 109.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGE01712.1 - 7.4e-14 51.5 0.0 1.9e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGE01712.1 - 1.6e-11 44.4 0.0 4.6e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGE01712.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain ATP_bind_1 PF03029.17 EGE01712.1 - 0.039 13.7 0.1 0.15 11.8 0.1 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGE01712.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Abhydrolase_6 PF12697.7 EGE01713.1 - 6.5e-13 49.8 0.1 1.2e-12 49.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE01713.1 - 3.7e-08 32.9 0.0 7.8e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGE01713.1 - 1.4e-07 31.5 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGE01713.1 - 0.00018 21.5 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EGE01713.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 EGE01713.1 - 0.085 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family TLD PF07534.16 EGE01715.1 - 1.3e-20 74.1 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EGE01715.1 - 0.00056 20.9 0.4 0.002 19.1 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function NMT_C PF02799.15 EGE01716.1 - 1e-89 299.6 0.3 1.6e-89 299.0 0.3 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGE01716.1 - 1.3e-71 239.6 0.0 2.3e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EGE01716.1 - 7e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mur_ligase_M PF08245.12 EGE01717.1 - 6.5e-07 29.5 0.0 5.3e-05 23.3 0.0 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.18 EGE01718.1 - 1.7e-83 280.6 0.0 2.3e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 EGE01718.1 - 0.018 15.5 0.1 1 9.8 0.0 3.0 3 0 0 3 3 3 0 FUN14 family CHRD PF07452.12 EGE01718.1 - 0.083 13.9 0.0 17 6.4 0.0 2.4 2 0 0 2 2 2 0 CHRD domain zf-CCCH PF00642.24 EGE01719.1 - 3.2e-19 68.3 29.7 2.2e-06 27.4 0.7 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE01719.1 - 1.5e-11 43.9 33.7 0.00058 19.8 2.5 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EGE01719.1 - 1.3e-08 35.5 28.3 0.00022 21.9 1.0 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EGE01719.1 - 4.1e-05 23.3 0.8 4.1e-05 23.3 0.8 5.0 5 0 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGE01719.1 - 0.11 12.7 11.5 6.4 7.0 4.1 3.5 2 1 1 3 3 3 0 Zinc-finger containing family TRP_N PF14558.6 EGE01719.1 - 0.37 11.2 3.5 16 5.9 0.0 3.1 2 1 1 3 3 3 0 ML-like domain zf-C3H1 PF10650.9 EGE01719.1 - 3.2 7.6 11.2 1.2 9.0 0.4 3.5 3 0 0 3 3 3 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.28 EGE01720.1 - 1e-62 212.7 0.0 1.2e-62 212.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ThrE PF06738.12 EGE01720.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Glyco_hydro_75 PF07335.11 EGE01721.1 - 1e-61 208.0 0.4 1.1e-61 207.8 0.4 1.0 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF3712 PF12505.8 EGE01722.1 - 4.7e-28 98.0 2.6 9.3e-28 97.0 1.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) ASFV_J13L PF05568.11 EGE01722.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4307 PF14155.6 EGE01722.1 - 0.086 12.7 0.4 0.17 11.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Sel1 PF08238.12 EGE01724.1 - 4e-11 43.2 12.1 0.0003 21.3 2.6 4.1 4 0 0 4 4 4 3 Sel1 repeat CDC45 PF02724.14 EGE01724.1 - 0.63 8.3 2.8 0.99 7.6 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.28 EGE01725.1 - 1.8e-25 90.3 1.6 3.1e-24 86.3 1.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 EGE01725.1 - 0.0013 18.0 0.3 0.0057 16.0 0.3 2.1 1 1 0 1 1 1 1 Putative glycoside hydrolase Family 18, chitinase_18 GDI PF00996.18 EGE01725.1 - 0.012 14.2 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Syndecan PF01034.20 EGE01726.1 - 0.091 12.7 0.9 0.22 11.4 0.9 1.6 1 0 0 1 1 1 0 Syndecan domain Myc_target_1 PF15179.6 EGE01726.1 - 0.28 11.0 7.8 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Myc target protein 1 TFIIA PF03153.13 EGE01726.1 - 2 8.4 17.9 2.4 8.1 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box_4 PF15966.5 EGE01727.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 F-box F-box PF00646.33 EGE01727.1 - 0.014 15.3 0.1 0.014 15.3 0.1 3.1 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EGE01727.1 - 0.035 14.0 1.6 0.1 12.5 0.2 2.5 2 0 0 2 2 2 0 F-box-like DUF1776 PF08643.10 EGE01729.1 - 5.8e-88 295.1 0.0 7e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.10 EGE01730.1 - 2.1e-67 226.9 0.1 3.3e-67 226.3 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EGE01730.1 - 0.00016 20.9 1.4 0.00016 20.9 1.4 3.1 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 EGE01730.1 - 0.0068 16.5 2.0 0.014 15.4 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 EGE01730.1 - 0.018 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_M54 PF07998.11 EGE01730.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DZR PF12773.7 EGE01730.1 - 0.57 10.3 7.0 3.5 7.7 2.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EGE01730.1 - 0.9 9.9 4.8 15 6.0 0.8 2.7 2 0 0 2 2 2 0 C1 domain SVIP PF15811.5 EGE01730.1 - 3.4 8.2 6.1 21 5.7 0.7 2.8 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Pkinase PF00069.25 EGE01731.1 - 1.8e-21 76.7 0.0 1e-20 74.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01731.1 - 4.8e-07 29.3 0.1 0.00045 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01731.1 - 0.066 12.0 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Regulator_TrmB PF11495.8 EGE01732.1 - 0.11 11.6 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Trp_DMAT PF11991.8 EGE01734.1 - 7.7e-103 344.7 0.0 8.9e-103 344.5 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase FAD_binding_3 PF01494.19 EGE01735.1 - 7.8e-13 48.4 1.2 1.4e-11 44.3 1.2 2.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGE01735.1 - 1.1e-06 28.0 1.1 2.6e-06 26.8 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGE01735.1 - 1.2e-06 28.0 1.1 0.0014 17.9 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE01735.1 - 4.4e-05 22.4 0.8 0.0018 17.1 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGE01735.1 - 0.00068 19.3 3.0 0.31 10.6 1.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGE01735.1 - 0.0024 17.2 0.1 1 8.5 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGE01735.1 - 0.0036 16.6 0.4 0.0065 15.8 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGE01735.1 - 0.0064 15.6 1.4 0.0066 15.6 0.5 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGE01735.1 - 0.0069 15.8 0.4 0.01 15.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE01735.1 - 0.019 15.2 0.4 0.07 13.4 0.2 2.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain AMP-binding PF00501.28 EGE01737.1 - 3.8e-74 249.8 0.0 6.1e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGE01737.1 - 1.4e-53 182.2 0.0 2.7e-31 108.8 0.0 4.5 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EGE01737.1 - 2.5e-26 91.8 0.3 5.8e-12 45.8 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE01737.1 - 0.0029 18.6 0.0 0.0097 16.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GRIP PF01465.20 EGE01737.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 GRIP domain DFRP_C PF16543.5 EGE01737.1 - 0.2 12.2 0.2 0.42 11.1 0.2 1.5 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 Ribonuclease PF00545.20 EGE01738.1 - 1.8e-07 31.8 0.0 2.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.32 EGE01739.1 - 1.8e-46 155.1 34.3 2.6e-05 24.9 0.2 12.2 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.12 EGE01739.1 - 9.4e-22 77.4 0.0 2.4e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGE01739.1 - 8.5e-21 74.1 6.2 0.012 15.9 0.0 9.9 5 2 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE01739.1 - 8.2e-09 34.9 0.9 0.31 10.0 0.2 5.1 3 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGE01739.1 - 9.4e-06 24.5 1.3 0.52 8.9 0.0 5.4 6 0 0 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGE01739.1 - 1.3e-05 24.7 0.0 0.39 10.0 0.0 3.8 4 0 0 4 4 4 2 WD40-like domain Frtz PF11768.8 EGE01739.1 - 0.0014 17.1 0.0 0.073 11.4 0.0 2.4 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 EGE01739.1 - 0.098 12.7 0.0 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat P34-Arc PF04045.14 EGE01740.1 - 3.8e-86 288.7 0.0 4.9e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF2158 PF09926.9 EGE01740.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF4294 PF14127.6 EGE01741.1 - 0.0023 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) PP2C PF00481.21 EGE01742.1 - 9.4e-05 22.2 0.0 0.36 10.4 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGE01742.1 - 0.0025 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGE01742.1 - 0.0026 17.7 0.1 0.0098 15.8 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.12 EGE01743.1 - 3.4e-19 69.1 0.2 5.5e-10 39.5 0.0 2.7 2 1 0 2 2 2 2 Fcf1 Cmc1 PF08583.10 EGE01744.1 - 1.2e-18 66.8 7.0 1.5e-18 66.6 7.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like HECA PF15353.6 EGE01744.1 - 0.072 13.3 1.7 0.092 13.0 1.7 1.2 1 0 0 1 1 1 0 Headcase protein family homologue WD40 PF00400.32 EGE01745.1 - 5e-13 49.3 13.1 0.00072 20.3 0.3 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EGE01745.1 - 0.00031 19.5 2.9 0.0096 14.6 1.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGE01745.1 - 0.0044 17.3 1.5 0.44 10.9 0.3 3.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4398 PF14346.6 EGE01745.1 - 1.5 9.5 8.8 3 8.5 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Macoilin PF09726.9 EGE01747.1 - 0.59 8.6 2.5 0.7 8.4 2.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGE01747.1 - 0.64 8.8 3.0 0.77 8.6 3.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRN3 PF05327.11 EGE01750.1 - 2.8e-168 561.0 0.0 2.8e-168 561.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_3 PF07859.13 EGE01751.1 - 1.6e-40 139.2 0.2 1.7e-30 106.5 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 EGE01751.1 - 3.3e-10 39.5 0.0 6e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2974 PF11187.8 EGE01751.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 EGE01751.1 - 0.038 13.6 0.1 0.087 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 EGE01751.1 - 0.18 10.7 0.0 0.38 9.6 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme tRNA-synt_2 PF00152.20 EGE01752.1 - 6.7e-70 235.6 0.0 9.7e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EGE01752.1 - 3.9e-17 62.2 0.0 5.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EGE01752.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGE01752.1 - 0.00086 18.9 0.0 0.99 8.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ank_2 PF12796.7 EGE01753.1 - 5.1e-29 100.7 0.1 1.7e-08 35.0 0.0 5.2 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE01753.1 - 2e-17 61.5 0.2 0.033 14.7 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 EGE01753.1 - 1.1e-16 60.9 1.5 0.0026 18.3 0.0 7.0 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EGE01753.1 - 2.2e-12 46.8 1.1 0.26 11.8 0.0 7.5 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EGE01753.1 - 1.6e-08 34.6 1.7 0.018 15.4 0.0 6.1 6 3 3 9 9 9 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EGE01753.1 - 0.039 13.9 0.0 13 5.8 0.0 4.0 4 2 1 5 5 5 0 Domain of unknown function (DUF3447) HEM4 PF02602.15 EGE01753.1 - 0.12 11.7 0.0 2.2 7.6 0.0 2.6 1 1 2 3 3 3 0 Uroporphyrinogen-III synthase HemD VWA_3_C PF18571.1 EGE01753.1 - 0.14 12.1 0.7 21 5.1 0.0 3.2 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain HLH PF00010.26 EGE01755.1 - 2.8e-13 49.6 0.3 2.8e-13 49.6 0.3 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Septin PF00735.18 EGE01757.1 - 3.7e-08 33.0 0.1 8e-06 25.3 0.0 3.0 2 1 0 2 2 2 1 Septin MCM PF00493.23 EGE01757.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Zeta_toxin PF06414.12 EGE01757.1 - 0.028 13.7 0.0 0.081 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGE01757.1 - 0.044 14.2 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 EGE01757.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EGE01757.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGE01757.1 - 0.15 11.7 0.0 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGE01757.1 - 0.22 10.7 0.1 1.2 8.2 0.0 2.1 3 0 0 3 3 3 0 G-protein alpha subunit HSP90 PF00183.18 EGE01758.1 - 1.6e-220 733.4 30.9 2e-220 733.1 30.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGE01758.1 - 6.5e-15 55.6 0.1 1.2e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGE01758.1 - 1e-08 35.1 0.1 1e-08 35.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ProQ PF04352.13 EGE01758.1 - 0.027 14.3 1.6 0.7 9.8 0.3 2.6 2 0 0 2 2 2 0 ProQ/FINO family LOH1CR12 PF10158.9 EGE01758.1 - 0.07 13.2 0.2 0.26 11.3 0.2 1.9 1 0 0 1 1 1 0 Tumour suppressor protein NTF2 PF02136.20 EGE01759.1 - 2.7e-23 82.8 0.3 4.3e-23 82.2 0.3 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EGE01759.1 - 1.9e-08 34.0 0.1 3.5e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGE01759.1 - 0.024 14.7 0.0 0.056 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Bac_DnaA PF00308.18 EGE01761.1 - 0.13 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Spt20 PF12090.8 EGE01762.1 - 1.2e-05 25.0 3.7 1.7e-05 24.5 3.7 1.2 1 0 0 1 1 1 1 Spt20 family TPR_17 PF13431.6 EGE01762.1 - 3.3e-05 23.9 0.9 0.56 10.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE01762.1 - 0.0087 15.7 3.1 0.16 11.6 0.0 3.8 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 EGE01762.1 - 0.038 13.8 0.2 7.9 6.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE01762.1 - 0.049 14.5 1.5 20 6.4 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2722 PF10846.8 EGE01762.1 - 0.064 12.2 5.5 0.09 11.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TPR_2 PF07719.17 EGE01762.1 - 0.099 12.8 0.1 11 6.4 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 EGE01762.1 - 0.87 9.1 9.1 1.3 8.5 9.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nnf1 PF03980.14 EGE01763.1 - 1.5e-32 112.2 4.7 3.6e-32 111.0 4.7 1.6 1 0 0 1 1 1 1 Nnf1 SHE3 PF17078.5 EGE01763.1 - 0.018 14.8 1.1 0.029 14.1 1.1 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 FlgN PF05130.12 EGE01763.1 - 0.018 15.6 2.1 0.018 15.6 2.1 2.1 2 0 0 2 2 2 0 FlgN protein DUF16 PF01519.16 EGE01763.1 - 0.024 15.1 0.6 0.043 14.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1887 PF09002.11 EGE01763.1 - 0.028 13.1 0.4 0.037 12.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Mod_r PF07200.13 EGE01763.1 - 0.044 13.9 6.5 0.034 14.2 4.4 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cnn_1N PF07989.11 EGE01763.1 - 0.045 13.9 0.9 0.045 13.9 0.9 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF948 PF06103.11 EGE01763.1 - 0.071 13.4 0.6 0.22 11.8 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.6 EGE01763.1 - 0.087 12.9 6.0 0.079 13.1 3.9 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 bZIP_1 PF00170.21 EGE01763.1 - 0.099 12.8 7.5 0.19 11.8 3.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor MCM_N PF14551.6 EGE01763.1 - 0.12 13.0 0.9 0.2 12.3 0.7 1.6 1 1 1 2 2 2 0 MCM N-terminal domain DUF4515 PF14988.6 EGE01763.1 - 0.13 12.1 6.1 0.13 12.0 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) NYD-SP28 PF14772.6 EGE01763.1 - 0.56 10.3 7.3 0.18 11.8 4.0 1.9 2 0 0 2 2 2 0 Sperm tail TMPIT PF07851.13 EGE01763.1 - 0.65 9.2 2.2 0.86 8.8 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EGE01763.1 - 0.68 10.0 3.7 1.2 9.2 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EGE01763.1 - 0.71 10.3 7.8 1.8 8.9 6.6 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 EGE01763.1 - 6.2 7.3 7.3 2.8 8.4 2.4 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 EGE01764.1 - 2e-75 253.5 0.0 3.3e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01764.1 - 4e-37 127.9 0.0 7e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE01764.1 - 0.00019 20.5 2.9 0.00058 18.9 0.1 2.5 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGE01764.1 - 0.035 13.4 0.1 0.035 13.4 0.1 2.5 2 2 1 3 3 3 0 Kinase-like APH PF01636.23 EGE01764.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family SelP_N PF04592.14 EGE01764.1 - 0.63 9.4 9.4 1 8.7 9.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Gag_p17 PF00540.18 EGE01764.1 - 0.69 9.9 2.7 1.3 9.0 2.7 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) SIR2 PF02146.17 EGE01765.1 - 6.4e-23 81.6 0.0 9.5e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family AATase PF07247.12 EGE01766.1 - 8e-19 67.6 0.0 1.7e-17 63.1 0.0 2.4 1 1 0 1 1 1 1 Alcohol acetyltransferase MRP-L27 PF09809.9 EGE01766.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L27 Cation_efflux PF01545.21 EGE01767.1 - 3.2e-55 186.9 5.8 4.3e-55 186.5 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGE01767.1 - 0.0001 22.4 0.0 0.00027 21.0 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FGGY_C PF02782.16 EGE01768.1 - 2.5e-30 105.7 0.0 6.1e-30 104.4 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGE01768.1 - 1.5e-19 70.5 0.0 4.5e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 EGE01769.1 - 9.4e-38 129.6 0.8 9.4e-38 129.6 0.8 2.7 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 EGE01769.1 - 0.026 14.7 0.1 1.1e+02 3.4 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat 14-3-3 PF00244.20 EGE01769.1 - 0.043 13.3 0.2 0.091 12.3 0.2 1.5 1 0 0 1 1 1 0 14-3-3 protein Esterase PF00756.20 EGE01770.1 - 1.1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGE01770.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EGE01770.1 - 0.00012 21.1 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 EGE01770.1 - 0.0013 18.3 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGE01770.1 - 0.0013 18.0 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGE01770.1 - 0.035 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EGE01770.1 - 0.048 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EGE01770.1 - 0.052 13.4 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EGE01770.1 - 0.053 12.2 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 EGE01770.1 - 0.085 12.4 0.0 0.29 10.6 0.0 1.8 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGE01770.1 - 0.13 12.1 0.0 1.5 8.6 0.0 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Peptidase_C50 PF03568.17 EGE01771.1 - 2.3e-150 501.1 0.0 5.3e-150 499.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EGE01771.1 - 3.6e-05 23.3 0.0 0.00034 20.1 0.0 2.5 1 1 0 1 1 1 1 CHAT domain TPR_14 PF13428.6 EGE01771.1 - 3.7 8.6 5.5 28 5.9 0.2 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RsbRD_N PF14361.6 EGE01771.1 - 6.6 7.5 6.1 1.2 9.9 0.6 2.9 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF5321 PF17254.2 EGE01772.1 - 1.2e-49 167.9 0.1 1.4e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF2852 PF11014.8 EGE01772.1 - 0.012 15.7 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Muted PF14942.6 EGE01772.1 - 0.021 15.2 1.8 0.029 14.7 1.8 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1611 PF07755.11 EGE01772.1 - 0.041 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain CREPT PF16566.5 EGE01772.1 - 0.066 13.4 0.8 0.093 12.9 0.8 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour YtpI PF14007.6 EGE01775.1 - 4.5 7.5 7.6 0.13 12.4 0.9 1.8 2 0 0 2 2 2 0 YtpI-like protein Fungal_trans PF04082.18 EGE01777.1 - 3.3e-20 72.2 0.3 6e-20 71.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01777.1 - 1.6e-09 37.8 12.2 1.6e-09 37.8 12.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EGE01778.1 - 1.4e-69 235.0 0.0 1.8e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.16 EGE01779.1 - 7.3e-10 38.6 0.2 2.4e-09 37.0 0.2 1.8 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.16 EGE01780.1 - 5.9e-35 120.8 24.7 6.5e-28 97.7 4.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01780.1 - 1.7e-08 33.8 3.3 1.7e-08 33.8 3.3 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGE01780.1 - 0.0013 17.7 0.9 0.0013 17.7 0.9 2.8 1 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 EGE01780.1 - 0.01 14.3 0.7 0.01 14.3 0.7 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) TFR_dimer PF04253.15 EGE01781.1 - 9.3e-31 106.4 0.0 1.5e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGE01781.1 - 1e-20 74.3 0.0 2.3e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGE01781.1 - 1.1e-09 38.1 0.0 5.1e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EGE01781.1 - 0.041 13.6 0.1 0.24 11.0 0.1 2.0 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 zf-C2H2_4 PF13894.6 EGE01782.1 - 0.00032 21.3 2.0 0.0075 17.0 0.1 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE01782.1 - 0.00069 19.9 5.1 0.012 16.1 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Ima1_N PF09779.9 EGE01782.1 - 0.069 14.0 0.4 0.21 12.4 0.4 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain IHABP4_N PF16174.5 EGE01782.1 - 4 8.0 13.0 0.8 10.3 2.9 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal RRM_1 PF00076.22 EGE01784.1 - 3.4e-42 142.1 0.0 2.5e-17 62.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 EGE01784.1 - 0.001 18.7 0.0 0.047 13.2 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain Limkain-b1 PF11608.8 EGE01784.1 - 0.0023 18.0 0.4 10 6.3 0.0 3.9 3 2 0 3 3 3 2 Limkain b1 RRM_3 PF08777.11 EGE01784.1 - 0.0038 17.3 0.0 1.8 8.7 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif PknH_C PF14032.6 EGE01784.1 - 0.0053 16.6 0.9 9.8 6.0 0.1 3.2 3 0 0 3 3 3 1 PknH-like extracellular domain RRM_5 PF13893.6 EGE01784.1 - 0.038 13.6 0.0 7.9 6.1 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE01784.1 - 0.12 12.2 0.0 4.4 7.2 0.0 2.8 2 1 0 2 2 2 0 Occluded RNA-recognition motif PH PF00169.29 EGE01785.1 - 0.00011 22.6 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 EGE01785.1 - 0.049 14.2 0.5 1.7 9.3 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5344) CHAD PF05235.14 EGE01785.1 - 0.053 13.5 0.8 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 CHAD domain MRP-63 PF14978.6 EGE01785.1 - 0.064 13.9 0.3 4.7 7.9 0.1 3.0 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Tim17 PF02466.19 EGE01786.1 - 3.3e-08 33.9 4.3 6.2e-08 33.0 4.3 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 EGE01786.1 - 0.16 12.0 0.9 1.1 9.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) RPT PF13446.6 EGE01787.1 - 3.3e-48 161.4 3.0 7.3e-18 64.3 0.0 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 EGE01787.1 - 1.5e-44 152.5 0.5 8.4e-44 150.0 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE01787.1 - 0.0014 18.3 4.6 0.0075 15.9 4.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Microvir_H PF04687.12 EGE01787.1 - 0.0088 15.5 0.7 0.015 14.7 0.7 1.2 1 0 0 1 1 1 1 Microvirus H protein (pilot protein) MFS_1 PF07690.16 EGE01788.1 - 2.6e-19 69.4 54.4 1.4e-18 67.0 44.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 EGE01788.1 - 8.8 6.4 6.9 1.8 8.6 0.1 2.8 3 0 0 3 3 3 0 PgaD-like protein CoA_trans PF01144.23 EGE01789.1 - 1.7e-104 348.0 2.0 1.4e-64 217.4 0.5 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.9 EGE01791.1 - 5.5e-91 304.2 0.0 8e-91 303.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 EGE01791.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) WSC PF01822.19 EGE01793.1 - 1.4e-08 34.8 8.0 2.6e-08 34.0 8.0 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EGE01793.1 - 2.4e-06 26.9 3.3 5.2e-06 25.8 3.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LapA_dom PF06305.11 EGE01793.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CDP-OH_P_transf PF01066.21 EGE01795.1 - 6.5e-13 49.2 0.6 1.8e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 EGE01796.1 - 5.7e-38 130.1 0.0 6.9e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 EGE01797.1 - 2.7e-30 105.6 0.0 1.2e-28 100.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGE01797.1 - 9e-16 57.8 0.1 1.7e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGE01797.1 - 5.3e-13 48.8 0.0 9.5e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGE01797.1 - 0.0025 17.8 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 TGS domain APH PF01636.23 EGE01798.1 - 9.4e-12 45.4 0.0 2.2e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 EGE01799.1 - 2.3e-24 85.9 0.3 1.6e-23 83.1 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01799.1 - 1.1e-09 38.2 13.3 2.2e-09 37.3 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coilin_N PF15862.5 EGE01799.1 - 0.0055 16.5 0.6 0.0055 16.5 0.6 1.7 2 0 0 2 2 2 1 Coilin N-terminus DUF4834 PF16118.5 EGE01799.1 - 0.042 14.8 1.0 0.042 14.8 1.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EGE01799.1 - 0.25 11.3 26.3 1.1 9.2 17.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 EGE01799.1 - 0.37 11.4 5.5 0.18 12.4 0.7 2.4 2 0 0 2 2 2 0 Ctr copper transporter family DUF778 PF05608.12 EGE01799.1 - 3.4 8.0 9.7 4.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF778) TERB2 PF15101.6 EGE01799.1 - 6.6 6.7 11.4 0.4 10.7 6.0 1.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 EGE01799.1 - 9.7 4.7 20.5 1.5 7.4 1.1 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Peptidase_M41 PF01434.18 EGE01800.1 - 3.7e-67 225.9 0.9 5.5e-67 225.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGE01800.1 - 7.3e-42 142.9 0.0 2.2e-41 141.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE01800.1 - 7.6e-12 44.8 0.1 2.2e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EGE01800.1 - 3.2e-10 40.3 1.3 6e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EGE01800.1 - 0.0025 17.8 0.0 0.013 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGE01800.1 - 0.0026 18.2 0.2 0.14 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGE01800.1 - 0.0066 16.7 0.2 1.1 9.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 EGE01800.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGE01800.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EGE01800.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_Rpc4 PF05132.14 EGE01800.1 - 0.041 14.3 0.4 0.041 14.3 0.4 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 TIP120 PF08623.10 EGE01800.1 - 0.24 11.1 1.4 15 5.4 0.8 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) AAA_17 PF13207.6 EGE01800.1 - 1.4 9.4 5.5 2.1 8.7 0.0 3.5 3 1 1 4 4 4 0 AAA domain DUF1295 PF06966.12 EGE01801.1 - 1.4e-39 136.1 7.8 2e-39 135.5 7.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGE01801.1 - 0.26 11.7 0.0 0.26 11.7 0.0 2.4 2 2 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PrgI PF12666.7 EGE01801.1 - 8.6 7.2 7.5 1.4 9.7 1.3 2.6 3 0 0 3 3 3 0 PrgI family protein Topoisom_bac PF01131.20 EGE01802.1 - 1.8e-100 336.8 0.0 2.4e-100 336.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGE01802.1 - 9.1e-16 58.0 0.0 2.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF730 PF05325.11 EGE01803.1 - 0.0063 16.5 0.7 0.11 12.6 0.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF730) HEPN_AbiU2 PF18734.1 EGE01803.1 - 0.032 13.8 0.2 0.23 10.9 0.2 2.5 1 0 0 1 1 1 0 AbiU2 Baculo_PEP_C PF04513.12 EGE01803.1 - 0.042 13.9 21.0 0.45 10.5 4.5 4.9 1 1 5 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm1_N PF18504.1 EGE01803.1 - 0.23 11.8 8.9 52 4.3 0.8 6.1 3 2 1 5 5 5 0 Csm1 N-terminal domain Mrpl_C PF18502.1 EGE01803.1 - 0.66 10.3 3.6 1.8 8.9 0.3 3.0 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain SlyX PF04102.12 EGE01803.1 - 0.93 10.2 21.0 4.7 7.9 0.3 7.5 5 3 2 7 7 7 0 SlyX ROS_MUCR PF05443.11 EGE01803.1 - 0.97 9.5 10.6 1.3 9.1 1.2 3.6 3 1 1 4 4 4 0 ROS/MUCR transcriptional regulator protein MIP-T3_C PF17749.1 EGE01803.1 - 2 8.4 25.3 12 5.9 0.1 4.8 3 1 1 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4149 PF13664.6 EGE01804.1 - 4.9e-26 91.0 0.9 4.9e-26 91.0 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_PK_bind PF08785.11 EGE01805.1 - 3e-37 127.4 0.2 1.2e-36 125.5 0.2 2.1 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EGE01805.1 - 4.1e-28 98.5 0.0 7.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGE01805.1 - 8.2e-05 22.4 0.0 0.0041 16.9 0.0 3.0 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EGE01805.1 - 0.017 15.4 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain PX PF00787.24 EGE01806.1 - 3.9e-16 59.0 0.0 1e-15 57.7 0.0 1.7 2 0 0 2 2 2 1 PX domain SIP1 PF04938.12 EGE01807.1 - 3.9e-11 43.1 0.0 4.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.20 EGE01808.1 - 2.6e-65 220.6 0.1 3.5e-65 220.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE01808.1 - 2.2e-06 27.5 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 EGE01809.1 - 6.8e-25 87.1 0.0 1.2e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE01809.1 - 1.3e-15 57.2 0.0 6.7e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGE01809.1 - 0.15 12.3 0.0 9 6.5 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EGE01810.1 - 7.8e-11 41.7 0.4 2.3e-10 40.2 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE01810.1 - 0.067 13.1 0.4 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 F-box domain Adaptin_N PF01602.20 EGE01811.1 - 5.9e-113 378.2 0.7 8.7e-113 377.6 0.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGE01811.1 - 7.4e-60 201.5 1.8 1.7e-59 200.3 1.8 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGE01811.1 - 4.3e-32 110.7 0.5 1.7e-31 108.7 0.1 2.3 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGE01811.1 - 1.8e-19 69.9 2.2 1.4e-12 47.8 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EGE01811.1 - 9.9e-10 38.7 9.3 0.0012 18.9 0.1 5.0 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGE01811.1 - 0.00043 20.3 6.6 0.42 11.0 0.3 5.9 7 0 0 7 7 7 1 HEAT repeat Alpha_adaptin_C PF02296.16 EGE01811.1 - 0.0017 18.5 0.0 0.0071 16.5 0.0 2.1 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain HEAT_PBS PF03130.16 EGE01811.1 - 0.011 16.3 4.8 2.4 9.1 0.1 4.8 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EGE01811.1 - 0.47 11.0 4.5 0.23 12.0 0.4 2.7 3 0 0 3 3 3 0 HEAT-like repeat Phosducin PF02114.16 EGE01812.1 - 4.6e-15 55.3 0.1 5.6e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Phosducin Exog_C PF18026.1 EGE01812.1 - 0.99 9.5 6.2 7.6 6.7 2.6 2.4 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain bZIP_1 PF00170.21 EGE01813.1 - 8.6e-06 25.8 12.6 1.3e-05 25.2 12.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EGE01813.1 - 2.6e-05 24.0 6.3 3.9e-05 23.5 6.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EGE01813.1 - 0.0025 15.9 0.3 0.0031 15.5 0.3 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CCDC106 PF15794.5 EGE01813.1 - 0.013 15.3 7.2 0.017 14.8 4.5 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 bZIP_Maf PF03131.17 EGE01813.1 - 0.018 15.5 10.7 0.032 14.8 10.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Tmemb_cc2 PF10267.9 EGE01813.1 - 0.031 13.4 2.8 0.047 12.8 2.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RR_TM4-6 PF06459.12 EGE01813.1 - 0.058 13.2 1.8 0.084 12.7 1.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAS PF13851.6 EGE01813.1 - 0.058 12.7 6.6 0.087 12.2 6.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 EGE01813.1 - 0.084 12.8 1.7 0.18 11.7 1.7 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TMF_TATA_bd PF12325.8 EGE01813.1 - 0.13 12.5 4.4 0.23 11.7 4.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PAP1 PF08601.10 EGE01813.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.4 2 1 0 2 2 2 0 Transcription factor PAP1 bZIP_2 PF07716.15 EGE01813.1 - 0.38 10.9 16.7 0.61 10.2 15.6 1.8 1 1 1 2 2 2 0 Basic region leucine zipper CDC45 PF02724.14 EGE01813.1 - 1.2 7.4 7.0 1.5 7.0 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EGE01814.1 - 6e-26 91.4 0.0 7.6e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01814.1 - 7.8e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE01814.1 - 5.3e-09 35.3 0.0 7.5e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE01814.1 - 0.00025 21.0 0.0 0.0016 18.4 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kelch_5 PF13854.6 EGE01815.1 - 2.2e-34 116.9 6.3 4.8e-09 36.0 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGE01815.1 - 3.8e-30 103.6 12.2 4.6e-08 32.9 1.3 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGE01815.1 - 1e-28 99.0 23.1 1.3e-07 31.7 0.6 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGE01815.1 - 8.5e-28 95.7 4.2 2.2e-12 46.4 0.2 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EGE01815.1 - 2e-25 88.2 9.0 8.6e-11 41.7 0.5 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGE01815.1 - 6.9e-23 79.7 7.3 1.2e-08 34.6 0.2 6.4 6 0 0 6 6 6 4 Kelch motif YabA PF06156.13 EGE01815.1 - 0.0097 16.5 2.7 0.0097 16.5 2.7 7.6 4 2 3 7 7 7 1 Initiation control protein YabA DUF4396 PF14342.6 EGE01817.1 - 3.4e-45 153.9 3.1 4.7e-45 153.4 3.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) RSRP PF17069.5 EGE01818.1 - 0.27 10.8 11.9 0.3 10.6 11.9 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Raptor_N PF14538.6 EGE01819.1 - 1e-48 165.0 0.0 2e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGE01819.1 - 0.002 18.9 16.5 0.33 11.9 0.1 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat Peptidase_C14 PF00656.22 EGE01819.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Caspase domain HEAT PF02985.22 EGE01819.1 - 0.0034 17.5 0.7 1.5 9.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGE01819.1 - 0.0085 16.5 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 HEAT repeats BBS2_Mid PF14783.6 EGE01819.1 - 0.019 15.0 0.2 1 9.4 0.1 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 EGE01819.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.6 EGE01821.1 - 4.7e-13 49.2 5.4 7.4e-13 48.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGE01821.1 - 3.9e-09 36.1 2.5 3.9e-09 36.1 2.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGE01821.1 - 5.9e-09 35.6 4.8 9.6e-09 35.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE01821.1 - 1e-08 35.3 3.1 2.2e-08 34.2 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGE01821.1 - 1.9e-08 34.1 4.0 3e-08 33.4 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EGE01821.1 - 8.5e-08 32.1 0.0 2.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EGE01821.1 - 1.5e-07 31.3 3.1 2.3e-07 30.7 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGE01821.1 - 3.9e-06 26.6 3.1 5.8e-06 26.1 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE01821.1 - 6.8e-06 26.0 2.2 1.1e-05 25.3 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGE01821.1 - 0.00067 19.7 0.7 0.0013 18.8 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGE01821.1 - 0.0014 18.4 3.1 0.0024 17.7 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGE01821.1 - 0.025 14.8 2.6 0.055 13.6 2.6 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGE01821.1 - 0.062 12.9 3.1 0.12 12.0 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGE01821.1 - 0.071 13.3 3.0 0.18 12.0 3.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EGE01821.1 - 0.36 11.0 4.3 0.75 10.0 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EGE01821.1 - 0.46 10.3 3.2 0.83 9.5 3.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EGE01821.1 - 0.61 10.0 3.1 1.1 9.2 3.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EGE01821.1 - 2 8.8 3.7 3.8 7.9 3.7 1.5 1 0 0 1 1 1 0 RING-like domain SelK_SelG PF10961.8 EGE01821.1 - 4.3 8.0 0.0 4.3 8.0 0.0 4.5 3 2 0 4 4 3 0 Selenoprotein SelK_SelG EI24 PF07264.11 EGE01822.1 - 4.6e-13 49.8 4.5 6.8e-13 49.2 4.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LysM PF01476.20 EGE01823.1 - 2.4e-05 24.3 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain Chitin_bind_1 PF00187.19 EGE01823.1 - 0.01 16.3 24.6 0.013 16.0 17.5 3.2 2 0 0 2 2 2 0 Chitin recognition protein FAD_binding_3 PF01494.19 EGE01824.1 - 3.2e-07 29.9 0.1 4.9e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE01824.1 - 3.1e-05 24.1 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE01824.1 - 5.5e-05 22.5 0.1 0.0021 17.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE01824.1 - 0.00027 20.6 0.3 0.00044 20.0 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGE01824.1 - 0.0012 17.8 0.9 0.0013 17.6 0.1 1.4 2 0 0 2 2 2 1 Tryptophan halogenase DUF1967 PF09269.11 EGE01824.1 - 0.014 15.3 0.7 0.11 12.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) MCRA PF06100.11 EGE01824.1 - 0.017 14.0 0.1 0.025 13.4 0.1 1.1 1 0 0 1 1 1 0 MCRA family AlaDh_PNT_C PF01262.21 EGE01824.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGE01824.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 EGE01824.1 - 0.17 11.0 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FHA PF00498.26 EGE01826.1 - 1.8e-16 60.3 0.0 4.4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGE01826.1 - 0.0002 21.6 0.0 0.00057 20.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MscS_porin PF12795.7 EGE01826.1 - 0.24 10.9 26.6 0.11 12.0 6.5 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Jnk-SapK_ap_N PF09744.9 EGE01826.1 - 0.74 10.0 17.8 0.88 9.8 6.4 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 EGE01826.1 - 1.7 7.5 7.0 0.29 10.0 0.7 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein CENP-Q PF13094.6 EGE01826.1 - 9.5 6.4 25.6 0.23 11.7 1.8 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Romo1 PF10247.9 EGE01827.1 - 5.4e-28 97.1 16.6 7.2e-28 96.7 16.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGE01827.1 - 0.025 14.9 5.5 0.03 14.7 5.5 1.2 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.6 EGE01827.1 - 0.15 11.9 3.5 0.78 9.6 0.4 2.4 2 0 0 2 2 2 0 Glycine-zipper domain LysM PF01476.20 EGE01828.1 - 1.2e-20 73.3 0.1 9.3e-07 28.8 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_23 PF13384.6 EGE01828.1 - 0.032 14.0 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain Pex14_N PF04695.13 EGE01828.1 - 0.049 14.3 6.4 0.15 12.7 3.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1153 PF06627.11 EGE01828.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1153) UPF0203 PF05254.12 EGE01828.1 - 0.36 11.1 3.1 3.4 8.0 0.4 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0203) MGC-24 PF05283.11 EGE01831.1 - 0.37 11.3 4.7 0.49 10.9 4.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_8 PF13855.6 EGE01832.1 - 2.3e-09 36.9 0.8 5.7e-09 35.6 0.8 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGE01832.1 - 5e-06 26.8 1.2 1.2e-05 25.6 0.5 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Ribosomal_S14 PF00253.21 EGE01834.1 - 1.3e-20 72.9 0.7 3.2e-20 71.6 0.2 1.9 3 0 0 3 3 3 1 Ribosomal protein S14p/S29e ATP-synt_J PF04911.12 EGE01835.1 - 1.8e-26 91.4 0.4 2.1e-26 91.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.11 EGE01836.1 - 2.8e-50 170.3 3.8 3.9e-50 169.8 3.8 1.2 1 0 0 1 1 1 1 Spc19 LPD30 PF18850.1 EGE01836.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Rsm22 PF09243.10 EGE01837.1 - 6.8e-29 101.0 0.0 3.9e-28 98.5 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EGE01837.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BNR_2 PF13088.6 EGE01838.1 - 3.1e-12 46.4 0.0 5.6e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain BNR_3 PF13859.6 EGE01838.1 - 5.2e-10 39.1 0.0 7.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 BNR repeat-like domain Rogdi_lz PF10259.9 EGE01839.1 - 1.9e-84 283.3 0.0 2.2e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP70 PF00012.20 EGE01840.1 - 2.8e-83 280.1 1.0 2.8e-83 280.1 1.0 2.0 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGE01840.1 - 3.7e-11 42.4 0.7 5.5e-11 41.9 0.7 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EGE01840.1 - 0.0028 16.7 0.1 2.2 7.2 0.0 2.7 2 1 1 3 3 3 2 Type IV pilus assembly protein PilM; PI3K_1B_p101 PF10486.9 EGE01840.1 - 0.11 10.2 0.4 0.18 9.6 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 EGE01840.1 - 0.39 11.1 5.9 0.87 10.0 5.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EGE01840.1 - 0.47 10.1 2.9 0.28 10.8 0.6 1.7 2 0 0 2 2 2 0 FAM176 family Radial_spoke PF04712.12 EGE01840.1 - 0.91 8.4 5.3 1.5 7.7 5.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 EGE01840.1 - 7.6 4.5 6.5 11 3.9 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi EamA PF00892.20 EGE01841.1 - 0.00039 20.6 33.1 0.0031 17.7 8.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family SBP_bac_1 PF01547.25 EGE01841.1 - 0.069 13.1 0.1 12 5.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein DUF1077 PF06417.12 EGE01841.1 - 0.14 12.2 6.8 1.4 8.9 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1077) Rpp20 PF12328.8 EGE01842.1 - 1.7e-44 151.1 9.2 3.4e-44 150.1 9.2 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EGE01842.1 - 1.8e-14 53.3 0.3 3.3e-14 52.4 0.3 1.4 1 0 0 1 1 1 1 Alba 7TMR-HDED PF07697.11 EGE01842.1 - 0.0018 18.4 0.1 0.0023 18.1 0.1 1.1 1 0 0 1 1 1 1 7TM-HD extracellular SRP14 PF02290.15 EGE01842.1 - 0.33 11.3 2.6 0.45 10.9 2.1 1.5 1 1 0 1 1 1 0 Signal recognition particle 14kD protein KH_6 PF15985.5 EGE01844.1 - 6.6e-16 58.4 0.1 1.2e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EGE01844.1 - 0.026 14.4 0.7 0.14 12.1 0.2 2.3 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain PhzC-PhzF PF02567.16 EGE01845.1 - 0.0029 17.1 0.1 0.0038 16.7 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Glyco_transf_24 PF18404.1 EGE01848.1 - 6.6e-149 494.6 1.0 9.7e-149 494.1 1.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGE01848.1 - 6.9e-64 216.2 0.0 1.5e-62 211.8 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGE01848.1 - 1.4e-46 158.8 1.7 1.6e-46 158.6 0.3 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EGE01848.1 - 7.1e-44 150.3 0.1 2e-42 145.6 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGE01848.1 - 5.9e-43 146.0 1.2 1.1e-42 145.1 0.2 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGE01848.1 - 2.4e-41 140.2 0.0 4.7e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EGE01848.1 - 0.00087 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Amidohydro_1 PF01979.20 EGE01849.1 - 2e-24 86.6 0.0 8.5e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGE01849.1 - 3.8e-11 43.1 0.0 1e-05 25.2 0.0 2.4 3 0 0 3 3 3 2 Amidohydrolase family Arylsulfotran_N PF17425.2 EGE01849.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain Glyco_hydro_26 PF02156.15 EGE01849.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 Vma12 PF11712.8 EGE01850.1 - 5.8e-42 143.1 0.0 8.5e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase HPP PF04982.13 EGE01850.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 HPP family Prefoldin PF02996.17 EGE01851.1 - 4e-31 107.4 0.1 4e-31 107.4 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGE01851.1 - 0.0021 18.0 0.7 0.017 15.0 0.1 2.3 2 0 0 2 2 2 1 Prefoldin subunit FlaC_arch PF05377.11 EGE01851.1 - 0.025 14.9 0.5 0.72 10.3 0.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Halogen_Hydrol PF10112.9 EGE01851.1 - 0.031 14.3 0.1 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DMPK_coil PF08826.10 EGE01851.1 - 0.045 13.9 3.2 0.82 9.8 0.7 2.4 2 0 0 2 2 2 0 DMPK coiled coil domain like End3 PF12761.7 EGE01851.1 - 0.048 13.8 2.2 0.084 13.0 0.3 2.1 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 LMP PF04778.12 EGE01851.1 - 0.06 13.3 0.2 6.5 6.6 0.0 2.1 2 0 0 2 2 2 0 LMP repeated region MetRS-N PF09635.10 EGE01851.1 - 0.095 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 MetRS-N binding domain CC2-LZ PF16516.5 EGE01851.1 - 0.14 12.6 3.9 3.2 8.2 0.8 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Glyco_transf_28 PF03033.20 EGE01852.1 - 4.9e-30 104.4 0.0 2.8e-29 101.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGE01852.1 - 0.0048 15.7 0.0 0.0074 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prenylcys_lyase PF07156.14 EGE01853.1 - 8.6e-93 311.3 0.0 1.1e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EGE01853.1 - 9.3e-13 48.3 0.0 1.4e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE01853.1 - 2e-11 43.9 0.0 5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGE01853.1 - 5.6e-08 32.8 0.1 0.00039 20.1 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE01853.1 - 0.0012 18.2 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE01853.1 - 0.0055 16.0 0.2 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EGE01853.1 - 0.011 15.8 0.1 0.39 10.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_18 PF00704.28 EGE01854.1 - 4.3e-66 223.8 0.0 6.6e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EGE01855.1 - 1e-08 35.1 0.0 0.00023 21.1 0.0 3.6 4 0 0 4 4 4 2 LysM domain FAM176 PF14851.6 EGE01856.1 - 0.19 11.4 5.2 0.36 10.5 5.2 1.4 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 EGE01856.1 - 0.21 11.0 8.8 0.31 10.4 8.8 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EGE01856.1 - 0.37 9.9 11.9 0.54 9.3 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EGE01856.1 - 0.52 8.3 12.7 0.78 7.8 12.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EGE01856.1 - 0.74 10.2 10.3 2 8.8 10.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EGE01856.1 - 3.6 5.7 10.9 4.8 5.3 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family PDCD2_C PF04194.13 EGE01857.1 - 3e-43 147.9 1.6 7.1e-43 146.7 0.0 2.3 2 1 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain CSN8_PSD8_EIF3K PF10075.9 EGE01858.1 - 4.3e-45 153.2 0.0 5.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Folliculin PF11704.8 EGE01859.1 - 3.1e-50 170.6 0.1 1e-49 168.9 0.0 2.0 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport CLP1_P PF16575.5 EGE01860.1 - 1.1e-28 100.4 0.0 3.9e-28 98.5 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF3095 PF11294.8 EGE01860.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) AAA_33 PF13671.6 EGE01860.1 - 0.027 14.6 0.4 0.25 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGE01860.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGE01860.1 - 0.22 10.5 0.0 1 8.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_polI_A34 PF08208.11 EGE01861.1 - 2.4e-41 142.1 32.5 2.4e-41 142.1 32.5 2.8 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.19 EGE01862.1 - 1.1e-206 686.1 0.0 1.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EGE01862.1 - 6.9e-06 25.5 0.0 2.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGE01862.1 - 0.00084 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGE01862.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3040 PF11239.8 EGE01862.1 - 0.16 12.3 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Med9 PF07544.13 EGE01863.1 - 4.8e-15 55.4 0.1 8.4e-15 54.6 0.1 1.6 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EGE01863.1 - 0.087 13.1 3.6 0.76 10.0 0.1 2.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Spc42p PF11544.8 EGE01863.1 - 0.18 11.8 0.1 0.34 11.0 0.1 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p iPGM_N PF06415.13 EGE01864.1 - 2e-78 262.7 0.0 2.8e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EGE01864.1 - 1.1e-70 237.9 0.0 1.3e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGE01864.1 - 0.00037 20.0 0.0 0.018 14.4 0.0 2.5 2 1 1 3 3 3 1 Sulfatase Alk_phosphatase PF00245.20 EGE01864.1 - 0.015 14.3 0.1 0.061 12.3 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Prefoldin_2 PF01920.20 EGE01865.1 - 6.2e-22 77.6 19.4 8.3e-22 77.2 19.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGE01865.1 - 3.9e-06 26.8 7.2 5.7e-06 26.3 7.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EGE01865.1 - 0.00089 19.2 1.2 0.00089 19.2 1.2 2.5 2 1 0 2 2 2 1 Prefoldin subunit Spc24 PF08286.11 EGE01865.1 - 0.0046 17.2 17.1 0.031 14.5 6.9 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Taxilin PF09728.9 EGE01865.1 - 0.0086 15.3 14.2 0.031 13.5 6.5 2.1 2 0 0 2 2 2 1 Myosin-like coiled-coil protein ABC_tran_CTD PF16326.5 EGE01865.1 - 0.012 15.9 20.1 0.24 11.7 3.0 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain YabA PF06156.13 EGE01865.1 - 0.013 16.1 9.6 0.31 11.7 0.4 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CCDC144C PF14915.6 EGE01865.1 - 0.013 14.6 13.5 0.16 11.0 3.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region TMF_TATA_bd PF12325.8 EGE01865.1 - 0.013 15.7 13.5 0.38 11.0 5.7 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 EGE01865.1 - 0.016 15.8 0.6 0.016 15.8 0.6 2.9 2 1 0 2 2 2 0 SlyX Siah-Interact_N PF09032.11 EGE01865.1 - 0.017 15.4 11.0 0.69 10.3 3.8 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal CENP-H PF05837.12 EGE01865.1 - 0.018 15.5 8.5 0.46 10.9 0.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Osmo_CC PF08946.10 EGE01865.1 - 0.032 14.5 5.0 0.032 14.5 5.0 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil SOGA PF11365.8 EGE01865.1 - 0.033 15.3 5.0 2 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein SOGA XhlA PF10779.9 EGE01865.1 - 0.04 14.1 2.4 0.04 14.1 2.4 2.2 2 1 0 2 2 2 0 Haemolysin XhlA TolA_bind_tri PF16331.5 EGE01865.1 - 0.042 13.9 16.0 0.79 9.8 6.3 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation HDV_ag PF01517.18 EGE01865.1 - 0.042 13.6 1.7 0.12 12.2 1.8 1.7 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen EzrA PF06160.12 EGE01865.1 - 0.057 11.6 15.6 0.025 12.8 3.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DegS PF05384.11 EGE01865.1 - 0.09 12.3 10.8 0.5 9.8 2.8 2.2 2 0 0 2 2 2 0 Sensor protein DegS Spc7 PF08317.11 EGE01865.1 - 0.092 11.6 18.4 0.14 11.0 18.4 1.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Swi5 PF07061.11 EGE01865.1 - 0.092 12.8 11.0 1.6 8.9 5.3 2.5 2 0 0 2 2 2 0 Swi5 PHM7_cyt PF14703.6 EGE01865.1 - 0.1 12.8 9.1 0.19 12.0 9.1 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter NPV_P10 PF05531.12 EGE01865.1 - 0.1 13.1 11.8 1.6 9.3 3.5 2.2 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.7 EGE01865.1 - 0.11 12.6 17.0 0.4 10.8 7.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Uso1_p115_C PF04871.13 EGE01865.1 - 0.12 12.8 17.4 0.18 12.2 8.1 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region End3 PF12761.7 EGE01865.1 - 0.12 12.5 11.7 0.17 12.0 11.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TPR_MLP1_2 PF07926.12 EGE01865.1 - 0.14 12.3 17.2 0.19 11.8 8.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 EGE01865.1 - 0.15 11.4 15.5 0.16 11.3 2.1 2.0 2 0 0 2 2 2 0 Tropomyosin GAS PF13851.6 EGE01865.1 - 0.15 11.4 17.1 0.17 11.2 6.9 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EGE01865.1 - 0.21 12.1 24.0 0.88 10.1 4.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region COG5 PF10392.9 EGE01865.1 - 0.22 11.7 5.9 2.9 8.1 1.1 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 EGE01865.1 - 0.28 10.5 13.1 0.55 9.5 13.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WEMBL PF05701.11 EGE01865.1 - 0.31 9.7 16.2 0.074 11.7 2.2 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Atg14 PF10186.9 EGE01865.1 - 0.35 9.9 9.5 0.51 9.4 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 betaPIX_CC PF16523.5 EGE01865.1 - 0.38 10.6 10.7 0.23 11.3 3.8 2.3 2 1 0 2 2 2 0 betaPIX coiled coil DUF5082 PF16888.5 EGE01865.1 - 0.41 10.9 17.3 1.7 8.9 17.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EGE01865.1 - 0.46 10.5 13.3 2.4 8.2 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 EGE01865.1 - 0.55 10.5 12.6 0.44 10.9 3.7 2.4 2 1 0 2 2 2 0 Rx N-terminal domain FlaC_arch PF05377.11 EGE01865.1 - 0.56 10.6 11.5 1.7 9.1 0.8 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) MtrG PF04210.13 EGE01865.1 - 0.56 10.1 5.5 0.43 10.5 1.3 2.5 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G ERM PF00769.19 EGE01865.1 - 0.66 9.8 19.5 1.3 8.7 19.5 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.15 EGE01865.1 - 0.72 9.7 23.7 0.64 9.8 3.7 3.2 2 1 1 3 3 3 0 Septum formation initiator MIP-T3_C PF17749.1 EGE01865.1 - 0.76 9.7 14.5 0.099 12.6 5.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DHR10 PF18595.1 EGE01865.1 - 0.77 9.8 21.1 0.76 9.8 8.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 EGE01865.1 - 1 9.4 12.5 1.6 8.8 1.2 2.1 1 1 0 2 2 2 0 Laminin Domain II Occludin_ELL PF07303.13 EGE01865.1 - 1 10.1 8.9 1.7 9.4 5.1 2.2 1 1 1 2 2 2 0 Occludin homology domain CENP-F_leu_zip PF10473.9 EGE01865.1 - 1 9.4 16.0 2.8 7.9 3.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4349 PF14257.6 EGE01865.1 - 1.3 8.4 17.9 0.18 11.3 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) BRE1 PF08647.11 EGE01865.1 - 1.5 9.0 18.0 0.35 11.0 2.2 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Snapin_Pallidin PF14712.6 EGE01865.1 - 1.6 9.2 13.1 0.44 11.0 1.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin CorA PF01544.18 EGE01865.1 - 1.7 7.9 7.9 0.38 10.0 0.9 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4164 PF13747.6 EGE01865.1 - 1.7 9.0 12.3 1.8 8.9 5.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4200 PF13863.6 EGE01865.1 - 1.7 9.0 19.1 4.1 7.8 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 EGE01865.1 - 1.8 8.4 12.3 0.61 9.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.19 EGE01865.1 - 2.4 7.8 14.4 3.9 7.1 5.8 2.1 2 0 0 2 2 2 0 GrpE Rootletin PF15035.6 EGE01865.1 - 2.4 8.1 13.4 0.51 10.3 6.5 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ACCA PF03255.14 EGE01865.1 - 2.8 7.8 9.7 3.8 7.4 0.9 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Sec34 PF04136.15 EGE01865.1 - 2.9 7.8 10.7 4 7.3 3.1 2.1 2 0 0 2 2 2 0 Sec34-like family CENP-Q PF13094.6 EGE01865.1 - 3.1 8.0 14.8 5.6 7.1 14.8 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.9 EGE01865.1 - 3.2 8.0 16.9 8.1 6.6 16.9 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 EGE01865.1 - 3.7 7.9 17.2 1.5 9.3 3.2 2.1 1 1 0 2 2 2 0 Fez1 HMMR_N PF15905.5 EGE01865.1 - 3.8 6.9 18.2 27 4.1 18.2 1.9 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Flagellin_N PF00669.20 EGE01865.1 - 3.8 7.6 11.3 0.69 10.0 4.1 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region OmpH PF03938.14 EGE01865.1 - 3.9 7.8 26.6 4.6e+02 1.1 26.9 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 EGE01865.1 - 4.1 5.9 16.6 0.083 11.5 2.7 2.0 1 1 1 2 2 2 0 AAA domain DUF641 PF04859.12 EGE01865.1 - 4.2 7.7 13.3 3.3 8.1 3.7 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Chibby PF14645.6 EGE01865.1 - 4.2 7.8 8.1 6.9 7.1 3.5 2.7 1 1 1 2 2 2 0 Chibby family Fib_alpha PF08702.10 EGE01865.1 - 4.4 7.5 15.4 1.5e+02 2.5 15.4 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family RPW8 PF05659.11 EGE01865.1 - 4.5 7.0 9.2 1.2 8.9 1.7 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 THOC7 PF05615.13 EGE01865.1 - 4.7 7.5 18.4 0.31 11.3 5.0 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Sas10_Utp3 PF04000.15 EGE01865.1 - 5.9 7.6 7.4 38 5.0 0.1 2.4 2 1 0 2 2 2 0 Sas10/Utp3/C1D family FapA PF03961.13 EGE01865.1 - 6.2 5.3 14.1 31 3.0 14.1 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2408 PF10303.9 EGE01865.1 - 7.2 7.2 11.0 29 5.2 11.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Allexi_40kDa PF05549.11 EGE01865.1 - 7.4 6.0 6.1 13 5.2 1.2 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Peptidase_S49_N PF08496.10 EGE01865.1 - 7.7 6.6 11.2 13 5.8 10.9 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal PspA_IM30 PF04012.12 EGE01865.1 - 7.8 6.0 18.7 46 3.5 18.7 1.8 1 1 0 1 1 1 0 PspA/IM30 family UPF0242 PF06785.11 EGE01865.1 - 8 6.5 22.8 1.7 8.7 9.3 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EGE01865.1 - 8.5 5.5 12.1 25 4.0 12.1 1.7 1 1 0 1 1 1 0 TMPIT-like protein COG2 PF06148.11 EGE01865.1 - 8.7 6.4 11.3 14 5.8 0.9 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.29 EGE01866.1 - 6.7e-43 146.3 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGE01866.1 - 2.3e-27 94.8 0.1 7.3e-27 93.1 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGE01866.1 - 9.3e-24 83.3 1.8 2e-23 82.2 1.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGE01866.1 - 1e-05 25.2 0.0 2.9e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGE01866.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE01866.1 - 2.4e-05 24.8 0.0 0.00013 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EGE01866.1 - 4.6e-05 23.6 0.0 0.00046 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGE01866.1 - 9.8e-05 22.2 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EGE01866.1 - 0.0001 22.3 0.0 0.00047 20.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGE01866.1 - 0.00018 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EGE01866.1 - 0.00019 21.4 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGE01866.1 - 0.00029 21.1 0.1 0.022 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE01866.1 - 0.00042 20.9 0.0 0.003 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGE01866.1 - 0.00082 18.6 0.0 0.0065 15.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGE01866.1 - 0.0014 18.8 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGE01866.1 - 0.0033 17.8 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 EGE01866.1 - 0.0039 16.9 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGE01866.1 - 0.011 16.2 0.0 0.051 14.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGE01866.1 - 0.016 14.8 0.2 0.72 9.4 0.1 2.7 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EGE01866.1 - 0.019 14.5 0.0 0.098 12.2 0.0 2.1 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 EGE01866.1 - 0.023 14.0 0.0 8.9 5.6 0.0 2.9 2 1 0 3 3 3 0 KaiC NACHT PF05729.12 EGE01866.1 - 0.037 14.0 0.0 0.37 10.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EGE01866.1 - 0.039 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI USP8_dimer PF08969.11 EGE01866.1 - 0.068 13.4 0.7 0.13 12.4 0.7 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain Parvo_NS1 PF01057.17 EGE01866.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EGE01866.1 - 0.081 12.4 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EGE01866.1 - 0.087 12.7 0.0 0.73 9.7 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Torsin PF06309.11 EGE01866.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 EGE01866.1 - 0.14 11.8 0.0 0.5 10.1 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain ParB PF08775.10 EGE01866.1 - 0.14 12.6 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 ParB family TPR_1 PF00515.28 EGE01866.1 - 0.17 11.8 0.6 0.6 10.0 0.6 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Cnn_1N PF07989.11 EGE01867.1 - 6.8e-23 80.6 6.4 6.8e-23 80.6 6.4 15.4 8 3 4 13 13 13 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EGE01867.1 - 1.2e-11 45.0 2.5 1.2e-11 45.0 2.5 5.9 5 1 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TMF_DNA_bd PF12329.8 EGE01867.1 - 3.4e-08 33.4 14.6 3.4e-08 33.4 14.6 16.1 9 6 9 18 18 18 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EGE01867.1 - 0.0096 15.9 14.9 0.0096 15.9 14.9 10.8 2 2 7 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SGT1 PF07093.11 EGE01868.1 - 4.9e-94 315.9 6.9 9.2e-83 278.6 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein eIF-1a PF01176.19 EGE01868.1 - 0.16 11.8 0.8 1.4 8.8 0.1 2.6 1 1 0 2 2 2 0 Translation initiation factor 1A / IF-1 AMMECR1 PF01871.17 EGE01869.1 - 9.4e-40 135.9 0.0 1.6e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 DUF4880 PF16220.5 EGE01869.1 - 0.026 14.4 0.2 0.065 13.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Hamartin PF04388.12 EGE01869.1 - 9.3 4.8 7.8 12 4.5 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EGE01871.1 - 5.1e-71 239.1 0.0 6.4e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01871.1 - 3.3e-28 98.7 0.0 4.3e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE01871.1 - 2.4e-07 30.4 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGE01871.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE01871.1 - 0.00056 19.9 0.1 0.00079 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE01871.1 - 0.00062 19.2 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1744 PF08490.12 EGE01872.1 - 3.5e-150 500.0 0.9 5.3e-150 499.4 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGE01872.1 - 9.5e-82 274.8 1.5 1.4e-81 274.2 0.3 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGE01872.1 - 1.3e-16 60.4 0.8 7.6e-13 48.0 0.0 4.4 4 1 0 4 4 4 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGE01872.1 - 8.9e-10 38.6 0.1 3e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGE01872.1 - 2.5e-05 24.4 0.0 9.2e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 EGE01873.1 - 2e-32 111.0 0.2 4.2e-32 110.0 0.0 1.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3767) Nop PF01798.18 EGE01875.1 - 5.8e-87 291.0 0.0 5.8e-87 291.0 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGE01875.1 - 4e-18 65.6 0.1 4e-18 65.6 0.1 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RP-C_C PF11800.8 EGE01875.1 - 0.057 13.5 9.8 0.45 10.6 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region RNA_polI_A34 PF08208.11 EGE01875.1 - 0.12 12.5 33.5 0.2 11.7 33.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 EGE01875.1 - 0.35 10.9 27.3 0.53 10.4 27.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CobT PF06213.12 EGE01875.1 - 6.3 6.1 22.7 6 6.2 21.1 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cpn60_TCP1 PF00118.24 EGE01876.1 - 8.7e-142 473.2 0.5 1.2e-132 443.0 1.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.18 EGE01877.1 - 6.3e-64 214.9 0.0 8.4e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGE01877.1 - 9.4e-15 54.0 0.2 1.7e-14 53.2 0.2 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain RRM_1 PF00076.22 EGE01878.1 - 6.2e-14 51.6 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1387 PF07139.11 EGE01878.1 - 0.32 10.7 1.7 0.71 9.5 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) AA_permease_2 PF13520.6 EGE01879.1 - 1.2e-52 179.2 37.3 1.4e-52 179.0 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE01879.1 - 2.3e-16 59.4 30.7 3.3e-16 59.0 30.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2721 PF11026.8 EGE01879.1 - 0.87 9.5 0.0 0.87 9.5 0.0 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2721) Sec23_trunk PF04811.15 EGE01880.1 - 3.6e-49 167.5 0.0 2.4e-48 164.8 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGE01880.1 - 1e-22 79.9 0.0 2.2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGE01880.1 - 1.9e-17 63.8 0.0 5e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGE01880.1 - 5.1e-16 58.4 4.6 9.9e-16 57.5 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGE01880.1 - 3e-06 27.0 0.0 6.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Bys1 PF04681.12 EGE01881.1 - 2.4e-06 27.6 0.2 3e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.17 EGE01881.1 - 0.0036 17.0 0.4 0.0086 15.7 0.2 1.6 1 1 0 1 1 1 1 Thaumatin family ABC_tran PF00005.27 EGE01882.1 - 1.2e-49 168.4 0.1 7.9e-25 88.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EGE01882.1 - 8.1e-48 162.6 33.5 2.2e-25 89.4 13.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EGE01882.1 - 6.6e-11 42.6 7.2 0.0025 17.7 0.1 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE01882.1 - 5.1e-09 35.9 0.7 0.0075 15.7 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGE01882.1 - 8.2e-09 36.3 1.3 0.00021 21.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGE01882.1 - 1.7e-07 31.3 1.9 0.018 15.0 1.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGE01882.1 - 2.5e-07 31.2 0.1 0.014 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGE01882.1 - 3.3e-06 26.7 2.5 0.087 12.6 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EGE01882.1 - 1.9e-05 24.7 0.4 0.051 13.5 0.1 2.4 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EGE01882.1 - 8.9e-05 22.5 0.1 0.0033 17.4 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EGE01882.1 - 9.3e-05 22.3 0.2 2.5 7.7 0.2 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGE01882.1 - 0.00016 22.0 0.2 0.54 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGE01882.1 - 0.00018 21.3 0.3 0.22 11.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGE01882.1 - 0.0003 21.2 0.7 1.2 9.6 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGE01882.1 - 0.00035 20.9 0.5 0.26 11.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGE01882.1 - 0.001 19.4 0.2 0.93 9.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 EGE01882.1 - 0.0029 17.2 0.6 0.38 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGE01882.1 - 0.0031 17.1 3.2 0.32 10.6 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 EGE01882.1 - 0.0034 16.8 0.2 2.3 7.5 0.0 2.4 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EGE01882.1 - 0.0066 16.8 0.5 1.1 9.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGE01882.1 - 0.011 15.8 0.2 6.7 6.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGE01882.1 - 0.016 15.7 0.1 3.2 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EGE01882.1 - 0.017 14.8 0.2 2.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EGE01882.1 - 0.018 14.1 0.1 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EGE01882.1 - 0.037 14.2 0.9 5.6 7.2 0.2 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGE01882.1 - 0.081 13.0 3.8 0.59 10.2 0.7 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EGE01882.1 - 0.088 13.2 0.6 6.9 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE01882.1 - 0.092 12.5 0.7 8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGE01882.1 - 0.095 12.6 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGE01882.1 - 0.11 12.4 0.7 17 5.3 0.3 2.7 3 0 0 3 3 2 0 NTPase PRK PF00485.18 EGE01882.1 - 0.14 11.9 0.7 10 5.8 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family PDR_CDR PF06422.12 EGE01882.1 - 0.14 12.1 0.2 0.46 10.4 0.2 1.8 1 0 0 1 1 1 0 CDR ABC transporter Pox_A32 PF04665.12 EGE01882.1 - 0.18 11.3 2.4 7.6 5.9 0.5 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_11 PF13086.6 EGE01882.1 - 0.2 11.4 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGE01882.1 - 0.21 10.8 0.4 13 4.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EGE01882.1 - 0.28 10.9 0.9 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.14 EGE01882.1 - 0.32 10.9 1.4 17 5.3 0.3 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 EGE01882.1 - 0.36 10.1 1.1 13 5.0 0.4 2.3 2 0 0 2 2 2 0 Zeta toxin Fungal_trans_2 PF11951.8 EGE01883.1 - 6.8e-68 229.2 0.1 9.1e-68 228.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01883.1 - 1.5e-09 37.8 10.0 2.7e-09 37.0 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EGE01883.1 - 0.21 11.5 6.6 0.72 9.9 6.6 2.0 1 0 0 1 1 1 0 AT hook motif O_anti_polymase PF01901.16 EGE01884.1 - 0.093 12.0 0.7 0.14 11.4 0.7 1.1 1 0 0 1 1 1 0 Putative O-antigen polymerase DUF2434 PF10361.9 EGE01885.1 - 2.3e-27 95.7 2.9 8.9e-25 87.3 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2434) DKCLD PF08068.12 EGE01885.1 - 0.1 12.6 0.6 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 DKCLD (NUC011) domain Gti1_Pac2 PF09729.9 EGE01886.1 - 1.7e-46 158.6 1.3 6.9e-39 133.8 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 EGE01888.1 - 4.6e-66 223.1 0.0 8.3e-65 218.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE01888.1 - 2.6e-07 30.5 0.0 7.8e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Complex1_LYR PF05347.15 EGE01888.1 - 0.032 14.3 0.1 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Lactamase_B_6 PF16661.5 EGE01890.1 - 2.4e-65 219.6 0.0 5.3e-65 218.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EGE01890.1 - 7.1e-46 156.5 0.2 7.1e-46 156.5 0.2 2.5 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EGE01890.1 - 4.2e-17 62.4 0.0 1.6e-16 60.5 0.0 2.1 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EGE01890.1 - 7.4e-13 48.2 0.0 1.7e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGE01890.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily CDT1_C PF16679.5 EGE01891.1 - 2.3e-19 69.6 0.5 5.1e-19 68.5 0.5 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Apolipoprotein PF01442.18 EGE01892.1 - 0.00072 19.5 0.3 0.00089 19.2 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoC-I PF04691.12 EGE01892.1 - 0.16 11.9 1.3 0.25 11.3 0.9 1.5 1 1 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF883 PF05957.13 EGE01892.1 - 0.52 10.9 4.3 1.7 9.3 4.1 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Frag1 PF10277.9 EGE01893.1 - 7.6e-41 140.1 6.3 7.6e-41 140.1 6.3 2.3 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EGE01893.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 EGE01894.1 - 1e-28 99.2 1.4 1e-28 99.2 1.4 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EGE01894.1 - 7.5e-05 23.2 4.5 0.022 15.5 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 EGE01894.1 - 0.0068 16.4 0.2 0.99 9.3 0.0 2.7 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 EGE01894.1 - 0.016 14.3 0.3 0.033 13.3 0.1 1.4 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference RF-1 PF00472.20 EGE01895.1 - 4.5e-20 71.7 1.2 4.5e-20 71.7 1.2 1.5 2 0 0 2 2 2 1 RF-1 domain HLH PF00010.26 EGE01895.1 - 0.0027 17.6 0.2 0.28 11.2 0.1 2.5 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain MRP-S28 PF10213.9 EGE01895.1 - 0.029 14.8 0.1 0.046 14.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein RRM_1 PF00076.22 EGE01896.1 - 2.7e-09 36.7 0.0 4.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE01896.1 - 0.008 15.8 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 EGE01897.1 - 1.8e-23 82.5 4.0 2.3e-23 82.2 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Swi6_N PF18530.1 EGE01897.1 - 0.055 13.6 0.0 0.12 12.6 0.0 1.4 2 0 0 2 2 2 0 Swi6 N-terminal domain CHCH PF06747.13 EGE01897.1 - 0.14 12.3 2.1 2 8.6 0.7 2.5 2 1 0 2 2 2 0 CHCH domain SYS1 PF09801.9 EGE01898.1 - 9.5e-54 181.5 8.0 1.1e-53 181.3 8.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.12 EGE01898.1 - 0.68 9.9 8.1 0.038 13.9 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 COG5 PF10392.9 EGE01899.1 - 1.3e-37 128.9 1.3 4e-37 127.3 0.0 2.4 3 0 0 3 3 3 1 Golgi transport complex subunit 5 zf-C2H2 PF00096.26 EGE01901.1 - 4.2e-05 23.8 11.7 0.017 15.5 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE01901.1 - 0.00011 22.4 5.8 0.00032 21.0 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE01901.1 - 0.00069 20.2 11.1 0.085 13.7 2.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger AMP-binding PF00501.28 EGE01903.1 - 5.4e-117 390.9 0.0 7.7e-53 179.6 0.0 3.2 2 1 1 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGE01903.1 - 6e-76 255.9 0.0 6.4e-40 137.2 0.0 3.1 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE01903.1 - 2.5e-21 75.8 0.0 3.1e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Transferase PF02458.15 EGE01903.1 - 0.026 13.2 0.1 0.062 11.9 0.0 1.5 2 0 0 2 2 2 0 Transferase family TAL_effector PF03377.13 EGE01903.1 - 0.18 12.1 0.6 0.59 10.5 0.6 1.9 1 0 0 1 1 1 0 TAL effector repeat MFS_1 PF07690.16 EGE01904.1 - 1.3e-39 136.2 46.5 1.3e-39 136.2 46.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE01904.1 - 1.4e-07 30.8 16.0 1.4e-07 30.8 16.0 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGE01904.1 - 5.1e-07 28.5 16.8 9.9e-06 24.2 6.3 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) VMR2 PF17055.5 EGE01904.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral matrix protein M2 p450 PF00067.22 EGE01905.1 - 6.9e-60 203.1 0.0 7.9e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_33 PF10017.9 EGE01906.1 - 6.2e-61 206.2 0.0 6.6e-35 120.7 0.0 2.0 1 1 1 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent MutS_V PF00488.21 EGE01907.1 - 4.3e-82 274.7 0.1 7.6e-82 273.9 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE01907.1 - 4.5e-37 128.1 0.6 1.4e-36 126.5 0.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EGE01907.1 - 6.7e-23 81.5 0.1 2.8e-22 79.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGE01907.1 - 1.6e-19 70.0 0.4 5.1e-19 68.4 0.4 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EGE01907.1 - 4.4e-17 62.4 0.0 4.4e-16 59.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.15 EGE01908.1 - 2.6e-75 252.6 9.6 5e-75 251.7 9.6 1.5 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) SOG2 PF10428.9 EGE01909.1 - 5.8 6.0 11.7 8.2 5.5 11.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UPF0203 PF05254.12 EGE01910.1 - 2.1e-26 91.9 3.5 2.5e-26 91.7 3.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EGE01910.1 - 3.4e-05 24.1 1.0 7.9e-05 22.9 1.0 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EGE01910.1 - 0.0025 17.8 4.0 0.14 12.2 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 EGE01910.1 - 0.17 12.1 4.8 3 8.1 5.1 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DNA_pol_A_exo1 PF01612.20 EGE01911.1 - 9.9e-41 139.4 0.5 1.6e-40 138.7 0.5 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGE01911.1 - 3.7e-31 107.7 2.3 8.3e-30 103.3 1.9 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGE01911.1 - 1.2e-11 44.4 0.6 2.7e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 HRDC domain AATF-Che1 PF13339.6 EGE01911.1 - 0.024 15.3 1.0 0.087 13.5 1.0 2.0 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4712 PF15830.5 EGE01911.1 - 0.22 11.2 4.3 10 5.7 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4712) DUF3446 PF11928.8 EGE01911.1 - 3.5 8.0 9.8 0.19 12.1 2.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain RasGAP PF00616.19 EGE01912.1 - 1.6e-57 194.6 0.1 1.1e-56 191.9 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGE01912.1 - 2.7e-31 108.6 5.6 2.7e-31 108.6 5.6 2.7 2 1 0 2 2 2 1 RasGAP C-terminus RsbU_N PF08673.10 EGE01912.1 - 0.67 10.1 3.9 1.3 9.2 0.3 2.9 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain CRAL_TRIO PF00650.20 EGE01913.1 - 8.4e-39 132.8 0.0 1.2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE01913.1 - 4.9e-07 29.8 0.3 4.9e-07 29.8 0.3 2.5 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGE01913.1 - 0.00049 20.3 0.0 0.00075 19.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RNA_pol_Rpc4 PF05132.14 EGE01913.1 - 1.1 9.7 5.5 1.9 8.9 5.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mis14 PF08641.12 EGE01914.1 - 1.3e-22 80.5 4.7 3.2e-22 79.3 4.7 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like RRN3 PF05327.11 EGE01914.1 - 0.4 9.2 3.2 0.55 8.7 3.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Acetyltransf_1 PF00583.25 EGE01917.1 - 6.7e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE01917.1 - 6.9e-12 45.4 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE01917.1 - 1.5e-11 44.5 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE01917.1 - 2.4e-11 43.5 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGE01917.1 - 9e-08 32.9 0.0 1.2e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGE01917.1 - 1.5e-06 27.9 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE01917.1 - 1.4e-05 25.1 0.1 3.6e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE01917.1 - 0.0003 20.8 0.0 0.00055 20.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGE01917.1 - 0.0033 17.6 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGE01917.1 - 0.029 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.15 EGE01918.1 - 7.5e-101 338.1 0.0 9.2e-101 337.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EGE01918.1 - 0.00042 21.0 0.0 0.00093 19.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EGE01918.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) PAP2_3 PF14378.6 EGE01919.1 - 6.6e-26 91.2 12.4 6.6e-26 91.2 12.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EGE01919.1 - 4.6e-09 36.1 4.5 4.6e-09 36.1 4.5 1.9 2 0 0 2 2 2 1 PAP2 superfamily Sugar_tr PF00083.24 EGE01921.1 - 5.3e-24 84.9 17.2 7.5e-16 58.0 2.4 2.7 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGE01921.1 - 3.4e-18 65.7 19.0 3.4e-18 65.7 19.0 2.4 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGE01921.1 - 2.3e-06 26.4 5.8 1.8e-05 23.5 3.9 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 EGE01921.1 - 0.014 13.6 0.3 0.014 13.6 0.3 1.6 2 0 0 2 2 2 0 BT1 family Pkinase PF00069.25 EGE01922.1 - 5.7e-06 25.9 0.0 1.5e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain YoeB_toxin PF06769.14 EGE01922.1 - 0.00033 20.6 0.0 0.00062 19.7 0.0 1.5 1 0 0 1 1 1 1 YoeB-like toxin of bacterial type II toxin-antitoxin system DUF1768 PF08719.11 EGE01923.1 - 2.5e-57 193.6 0.0 2.8e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 EGE01924.1 - 2e-30 106.0 0.0 1.5e-29 103.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01924.1 - 1.8e-07 30.7 0.0 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2275 PF10039.9 EGE01926.1 - 0.015 15.4 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) EMC3_TMCO1 PF01956.16 EGE01926.1 - 0.038 13.7 0.1 0.045 13.5 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TMEMspv1-c74-12 PF11044.8 EGE01926.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.7 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GRP PF07172.11 EGE01926.1 - 0.11 13.2 0.6 0.16 12.7 0.6 1.4 1 1 0 1 1 1 0 Glycine rich protein family DUF4307 PF14155.6 EGE01926.1 - 0.31 10.9 7.4 3.1 7.7 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) FeoB_associated PF12669.7 EGE01926.1 - 0.48 10.9 1.5 0.89 10.0 1.5 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EpuA PF11772.8 EGE01926.1 - 4.6 7.0 8.9 7 6.4 8.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta DUF1577 PF07614.11 EGE01929.1 - 0.067 12.3 0.1 0.095 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) DUF4058 PF13267.6 EGE01929.1 - 0.13 11.7 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4058) AMPK1_CBM PF16561.5 EGE01930.1 - 3.1e-17 62.6 0.0 7.8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EGE01930.1 - 0.021 15.2 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) cNMP_binding PF00027.29 EGE01931.1 - 8.4e-21 73.8 0.0 1.4e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 EGE01932.1 - 1.1e-09 39.0 0.0 1.8e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 EGE01933.1 - 4.2e-18 65.4 0.0 8.9e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EGE01933.1 - 0.14 12.5 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 FHA domain Snf7 PF03357.21 EGE01934.1 - 2.5e-32 111.8 18.0 2.5e-32 111.8 18.0 2.0 1 1 1 2 2 2 1 Snf7 Pecanex_C PF05041.15 EGE01934.1 - 0.0024 17.5 0.9 0.0033 17.0 0.9 1.1 1 0 0 1 1 1 1 Pecanex protein (C-terminus) CCDC24 PF15669.5 EGE01934.1 - 0.0028 17.6 5.3 0.0044 16.9 5.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family RTBV_P46 PF06216.11 EGE01934.1 - 0.75 8.6 3.2 1.1 8.1 2.7 1.4 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF3138 PF11336.8 EGE01934.1 - 1.2 7.6 6.8 1.1 7.8 5.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Ten1 PF12658.7 EGE01935.1 - 9.2e-40 135.4 0.0 1.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EGE01935.1 - 0.008 15.9 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Kelch_5 PF13854.6 EGE01936.1 - 1.1e-18 66.8 8.1 2.6e-08 33.7 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGE01936.1 - 9.9e-13 47.9 7.3 0.0095 15.9 0.2 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE01936.1 - 5.2e-11 42.4 6.8 0.04 14.2 0.2 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EGE01936.1 - 1.7e-10 40.9 6.6 0.003 17.8 0.0 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EGE01936.1 - 7.7e-07 28.6 5.7 0.053 13.1 0.2 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EGE01936.1 - 1.3e-06 28.1 1.4 0.16 12.0 0.1 4.5 4 0 0 4 4 4 2 Kelch motif BCAS2 PF05700.11 EGE01937.1 - 3.3e-66 222.9 2.6 3.7e-66 222.7 2.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.13 EGE01938.1 - 2.1e-202 673.3 0.0 2.4e-202 673.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGE01938.1 - 3.4e-58 196.2 0.1 5.2e-58 195.6 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal EI24 PF07264.11 EGE01940.1 - 3.2e-13 50.3 12.4 7.1e-13 49.2 12.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) COA2 PF17051.5 EGE01940.1 - 0.22 11.6 0.6 0.44 10.7 0.1 1.7 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 HNH PF01844.23 EGE01941.1 - 0.0031 17.7 2.3 0.0071 16.5 2.3 1.7 1 0 0 1 1 1 1 HNH endonuclease GTP_EFTU PF00009.27 EGE01943.1 - 7.3e-32 110.5 5.3 3.4e-30 105.0 5.3 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGE01943.1 - 5.8e-27 93.9 3.4 9.1e-27 93.3 1.2 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGE01943.1 - 1e-10 41.7 0.1 2.1e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EGE01943.1 - 5.4e-10 38.9 0.0 2.5e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EGE01943.1 - 2.6e-06 27.7 0.3 0.002 18.5 0.0 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Arf PF00025.21 EGE01943.1 - 9.9e-05 21.9 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGE01943.1 - 0.00015 21.3 0.1 0.00036 20.0 0.1 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGE01943.1 - 0.0012 18.7 3.5 0.069 13.0 0.2 2.8 1 1 1 2 2 2 1 RsgA GTPase Roc PF08477.13 EGE01943.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EGE01943.1 - 0.021 14.7 0.8 0.11 12.5 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu domain 4 FeoB_N PF02421.18 EGE01943.1 - 0.027 14.0 0.5 0.08 12.5 0.5 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EGE01943.1 - 0.03 14.4 0.1 6.3 6.8 0.0 3.0 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 EGE01943.1 - 0.11 12.2 0.3 0.33 10.7 0.3 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF4519 PF15012.6 EGE01943.1 - 3.5 7.9 4.4 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Mito_carr PF00153.27 EGE01944.1 - 1.6e-51 172.2 0.2 3.9e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 EGE01945.1 - 0.048 13.8 1.7 0.048 13.8 1.7 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S2 PF00318.20 EGE01946.1 - 2.2e-65 219.9 0.0 2.3e-64 216.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 Gly_transf_sug PF04488.15 EGE01947.1 - 1.1e-12 48.4 0.2 2.3e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Acyl_transf_3 PF01757.22 EGE01949.1 - 2.1e-39 135.5 31.2 2.5e-39 135.3 31.2 1.1 1 0 0 1 1 1 1 Acyltransferase family Rick_17kDa_Anti PF05433.15 EGE01951.1 - 4.2e-05 23.3 11.5 4.2e-05 23.3 11.5 2.9 3 1 0 3 3 3 1 Glycine zipper 2TM domain SURF6 PF04935.12 EGE01953.1 - 1.4e-50 171.9 31.7 1.4e-50 171.9 31.7 4.1 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EGE01953.1 - 4.8e-18 65.5 0.5 4.8e-18 65.5 0.5 8.1 6 2 0 6 6 6 2 60S ribosome biogenesis protein Rrp14 DUF2951 PF11166.8 EGE01953.1 - 0.36 11.1 0.1 0.36 11.1 0.1 5.2 4 3 2 6 6 6 0 Protein of unknown function (DUF2951) Fer4 PF00037.27 EGE01954.1 - 1.5e-13 50.0 16.5 5.7e-08 32.3 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGE01954.1 - 1.4e-12 48.0 10.0 2.2e-12 47.4 10.0 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGE01954.1 - 7.3e-10 39.6 9.8 9.4e-05 23.3 0.9 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGE01954.1 - 9.2e-10 38.5 31.2 4.6e-06 26.7 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGE01954.1 - 1.5e-08 35.0 2.6 0.00033 21.0 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGE01954.1 - 2.4e-08 34.0 21.3 4.3e-06 26.8 12.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGE01954.1 - 3.1e-08 33.7 9.7 6.3e-08 32.7 9.7 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGE01954.1 - 1.4e-06 28.1 17.1 0.00037 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EGE01954.1 - 4.3e-06 26.5 11.8 0.0091 16.0 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGE01954.1 - 7.9e-06 26.0 11.4 0.00028 21.2 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGE01954.1 - 0.00038 20.9 11.8 0.048 14.2 12.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGE01954.1 - 0.0087 16.3 5.6 0.49 10.7 0.3 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EGE01954.1 - 0.059 13.9 15.0 0.69 10.5 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EGE01954.1 - 0.074 13.2 9.0 1.1 9.5 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EGE01954.1 - 0.1 12.7 5.6 0.46 10.6 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 EGE01954.1 - 0.21 12.6 15.5 0.39 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EGE01954.1 - 0.89 10.4 12.1 2.1 9.2 1.6 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 EGE01955.1 - 1.3e-11 44.6 0.3 2.2e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGE01955.1 - 7.6e-05 22.9 0.2 0.00011 22.4 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 EGE01956.1 - 7e-68 228.7 0.2 9e-68 228.3 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.6 EGE01957.1 - 3.2e-22 80.0 0.0 7.1e-22 78.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGE01957.1 - 2.6e-05 24.2 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE01957.1 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 EGE01957.1 - 0.054 13.2 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF2183 PF09949.9 EGE01958.1 - 2.7e-32 111.0 0.0 8.7e-32 109.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EGE01958.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF3885 PF13021.6 EGE01958.1 - 0.13 12.4 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) CBS PF00571.28 EGE01962.1 - 1.8e-19 70.0 0.4 1.3e-06 28.7 0.0 4.4 4 0 0 4 4 4 4 CBS domain GCS PF03074.16 EGE01963.1 - 6e-175 581.9 0.0 7.4e-175 581.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF2811 PF10929.8 EGE01963.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) NDUF_B7 PF05676.13 EGE01964.1 - 7.2e-30 102.5 6.1 8.8e-30 102.2 6.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_4 PF13637.6 EGE01965.1 - 1.1e-12 48.1 0.1 1.2e-06 29.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE01965.1 - 1.3e-09 38.5 0.0 1.7e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE01965.1 - 6.3e-08 32.3 0.1 1.2e-05 25.3 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EGE01965.1 - 6.5e-07 29.5 0.1 1.5e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGE01965.1 - 1.4e-06 28.5 0.6 1.1e-05 25.6 0.0 2.8 3 1 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 EGE01965.1 - 0.00055 19.8 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain DUF3567 PF12091.8 EGE01965.1 - 0.12 12.5 0.5 0.29 11.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) DUF4407 PF14362.6 EGE01965.1 - 2.2 7.6 8.0 13 5.0 7.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 EGE01965.1 - 2.4 8.5 4.7 17 5.7 0.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Seryl_tRNA_N PF02403.22 EGE01965.1 - 3.9 7.8 6.2 12 6.2 5.8 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ThrE PF06738.12 EGE01968.1 - 2.5e-48 164.5 5.0 3.2e-42 144.6 0.0 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGE01968.1 - 4.7e-09 36.5 11.6 4.7e-09 36.5 11.6 3.0 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE CitT PF12431.8 EGE01969.1 - 0.18 12.2 1.2 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator P33MONOX PF15302.6 EGE01970.1 - 0.081 12.6 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase DUF5542 PF17696.1 EGE01970.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5542) PS_Dcarbxylase PF02666.15 EGE01971.1 - 1.7e-54 184.5 0.0 2.5e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGE01971.1 - 4.8e-37 126.4 0.0 1.9e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.6 EGE01971.1 - 0.0084 15.6 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EGE01971.1 - 0.032 13.8 0.0 0.11 12.1 0.0 2.0 1 0 0 1 1 1 0 EF hand GATA PF00320.27 EGE01973.1 - 3e-15 55.5 5.3 5.7e-15 54.6 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Carla_C4 PF01623.17 EGE01973.1 - 0.066 13.2 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein zinc_ribbon_9 PF14369.6 EGE01973.1 - 0.39 11.0 1.6 0.85 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon SusD-like_3 PF14322.6 EGE01975.1 - 0.011 16.1 0.2 0.017 15.5 0.2 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane HIRA_B PF09453.10 EGE01976.1 - 7.1 6.6 7.2 0.81 9.6 2.6 1.8 2 0 0 2 2 2 0 HIRA B motif Macro PF01661.21 EGE01978.1 - 4.3e-34 117.1 0.0 7.5e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Macro domain Ank_2 PF12796.7 EGE01980.1 - 2.6e-08 34.3 0.1 1e-07 32.4 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE01980.1 - 4e-06 26.8 0.8 0.0012 19.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGE01980.1 - 7.6e-06 26.4 0.0 2.1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGE01980.1 - 0.0011 19.3 0.1 0.05 14.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGE01980.1 - 0.0023 18.2 0.3 0.015 15.6 0.0 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.33 EGE01980.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 F-box domain Peptidase_S24 PF00717.23 EGE01981.1 - 0.00047 20.1 0.0 0.0025 17.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like AMP-binding PF00501.28 EGE01982.1 - 2.3e-93 313.1 0.0 5.8e-93 311.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EGE01982.1 - 2.8e-87 292.5 0.1 6.8e-87 291.2 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGE01982.1 - 1.7e-59 201.9 0.9 6.1e-59 200.1 1.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 EGE01982.1 - 9.4e-58 195.1 0.0 1.2e-56 191.4 0.0 2.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EGE01982.1 - 4.2e-44 150.6 0.0 7.1e-43 146.6 0.0 2.7 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGE01982.1 - 1.3e-38 131.6 0.3 3.2e-38 130.4 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGE01982.1 - 5e-23 81.2 0.0 2.8e-12 46.8 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGE01982.1 - 4.2e-13 49.7 0.0 4.5e-12 46.4 0.0 2.6 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGE01982.1 - 2.5e-12 46.8 0.0 1.1e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EGE01982.1 - 2.7e-08 34.7 0.0 7e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 EGE01982.1 - 8.8e-08 31.8 0.0 1.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EGE01982.1 - 8.6e-07 28.6 0.0 0.0015 18.0 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGE01982.1 - 9.7e-06 24.9 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGE01982.1 - 0.00022 20.4 0.0 0.43 9.5 0.1 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EGE01982.1 - 0.00031 20.2 0.3 0.0006 19.2 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.13 EGE01982.1 - 0.16 11.5 0.1 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family PhyH PF05721.13 EGE01983.1 - 1.4e-18 67.9 0.0 2.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_1_2 PF00155.21 EGE01984.1 - 1e-17 64.4 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGE01984.1 - 0.00021 20.2 0.0 0.0037 16.1 0.0 2.4 1 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 EGE01984.1 - 0.009 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V NmrA PF05368.13 EGE01985.1 - 1.7e-11 44.1 0.0 3.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE01985.1 - 2.3e-09 37.4 0.0 4.7e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGE01985.1 - 2.9e-05 24.0 0.3 4.4e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE01985.1 - 0.00015 21.3 0.0 0.00074 19.0 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CUE PF02845.16 EGE01985.1 - 0.17 11.6 0.3 27 4.6 0.1 2.5 2 0 0 2 2 2 0 CUE domain AA_permease_2 PF13520.6 EGE01986.1 - 3.1e-33 115.3 53.0 3.8e-33 115.0 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE01986.1 - 2.1e-07 29.9 46.1 2.7e-07 29.5 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease Tweety PF04906.13 EGE01986.1 - 0.44 9.1 3.2 0.39 9.3 0.8 2.1 2 0 0 2 2 2 0 Tweety PhyH PF05721.13 EGE01987.1 - 5.9e-22 79.0 0.0 7.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGE01987.1 - 0.035 12.9 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ank_3 PF13606.6 EGE01988.1 - 5.9e-10 38.5 0.2 0.0033 17.8 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGE01988.1 - 9.9e-10 38.9 0.0 2.7e-09 37.5 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE01988.1 - 1.1e-09 38.6 0.7 1.6e-07 31.7 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGE01988.1 - 2e-07 31.1 0.1 0.00064 20.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGE01988.1 - 7.2e-07 29.4 0.6 0.025 14.9 0.2 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) MAGE PF01454.19 EGE01989.1 - 5.5e-63 212.5 0.0 9.7e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 MAGE family DUF2997 PF11211.8 EGE01989.1 - 0.1 12.4 0.4 0.22 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Xan_ur_permease PF00860.20 EGE01990.1 - 1.8e-12 46.7 4.5 2.2e-12 46.4 4.5 1.0 1 0 0 1 1 1 1 Permease family Sulfate_transp PF00916.20 EGE01990.1 - 1.6e-05 23.9 2.8 1.9e-05 23.6 2.8 1.1 1 0 0 1 1 1 1 Sulfate permease family Pal1 PF08316.11 EGE01991.1 - 1.8e-18 67.6 1.4 2.1e-17 64.2 0.1 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein Med31 PF05669.12 EGE01993.1 - 2.2e-32 110.9 0.1 2.8e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 SOH1 Aldolase_II PF00596.21 EGE01995.1 - 8.2e-45 153.0 0.3 1.1e-44 152.6 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CSM2 PF16834.5 EGE01996.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding PHD PF00628.29 EGE01997.1 - 2.5e-10 40.1 7.8 5.4e-10 39.0 7.8 1.6 1 0 0 1 1 1 1 PHD-finger DUF2054 PF10218.9 EGE01997.1 - 0.038 14.1 3.7 0.085 12.9 3.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) Choline_kinase PF01633.20 EGE01997.1 - 0.061 12.9 0.2 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fungal_trans PF04082.18 EGE01998.1 - 8.4e-29 100.4 0.0 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE01998.1 - 7e-11 42.1 13.4 1.3e-10 41.2 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EGE01998.1 - 0.6 10.3 2.5 0.52 10.5 0.5 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain Pkinase PF00069.25 EGE01999.1 - 4e-19 69.0 0.0 1.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE01999.1 - 0.024 13.9 0.0 9.7 5.4 0.0 2.7 2 1 0 3 3 3 0 Protein tyrosine kinase zf-H2C2_2 PF13465.6 EGE02002.1 - 3.6e-05 24.0 3.3 3.6e-05 24.0 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGE02002.1 - 4.6e-05 23.6 2.8 4.6e-05 23.6 2.8 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE02002.1 - 0.00015 22.3 1.7 0.00015 22.3 1.7 3.5 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGE02002.1 - 0.0043 17.0 1.3 0.011 15.7 1.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE02002.1 - 0.0052 17.0 0.7 0.0052 17.0 0.7 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGE02002.1 - 0.0089 16.3 3.2 0.026 14.8 3.2 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon Forkhead PF00250.18 EGE02003.1 - 8.9e-34 115.6 1.6 1.8e-33 114.7 1.6 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EGE02003.1 - 2.8e-07 30.8 0.0 2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 EGE02003.1 - 0.013 15.9 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family Transp_cyt_pur PF02133.15 EGE02005.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L24e PF01246.20 EGE02006.1 - 1.2e-30 105.5 5.5 3.9e-30 103.9 5.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4820 PF16091.5 EGE02006.1 - 0.029 13.8 3.8 0.039 13.3 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4192 PF13830.6 EGE02006.1 - 0.072 13.1 0.6 0.08 13.0 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Pam16 PF03656.13 EGE02007.1 - 5.1e-06 26.5 0.2 1.1e-05 25.4 0.2 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EGE02007.1 - 0.00044 20.3 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EGE02007.1 - 0.0017 17.9 0.9 0.0017 17.9 0.9 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) Pkinase PF00069.25 EGE02008.1 - 1.5e-65 221.2 0.0 1.9e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02008.1 - 1.6e-30 106.3 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE02008.1 - 0.0087 15.0 0.0 0.024 13.6 0.0 1.8 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGE02008.1 - 0.054 12.8 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE02008.1 - 0.082 12.8 3.6 0.17 11.8 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family G_glu_transpept PF01019.21 EGE02009.1 - 9.9e-143 476.6 0.0 1.1e-142 476.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase p450 PF00067.22 EGE02010.1 - 2.5e-28 99.0 0.0 5.1e-28 98.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 PsiA PF06952.11 EGE02012.1 - 0.095 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 PsiA protein ICL PF00463.21 EGE02015.1 - 2.6e-299 993.1 1.6 3e-299 992.9 1.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGE02015.1 - 1.3e-11 44.5 0.0 3.3e-11 43.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase OTCace PF00185.24 EGE02015.1 - 0.14 12.3 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Trehalase PF01204.18 EGE02016.1 - 1.2e-196 654.5 0.1 1.5e-196 654.2 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EGE02016.1 - 7.4e-17 60.8 0.1 1.2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain adh_short_C2 PF13561.6 EGE02017.1 - 5.1e-49 166.9 0.0 6e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE02017.1 - 1.6e-46 158.3 0.0 1.9e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE02017.1 - 8.9e-07 29.0 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 KR domain HTH_Tnp_IS1 PF12759.7 EGE02017.1 - 0.062 12.9 0.1 59 3.4 0.1 3.2 3 0 0 3 3 3 0 InsA C-terminal domain OTU PF02338.19 EGE02018.1 - 7.1e-20 71.8 0.2 1.8e-19 70.5 0.0 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGE02018.1 - 1e-06 28.4 0.0 0.0012 18.3 0.0 2.5 1 1 0 2 2 2 2 Peptidase C65 Otubain DUF4407 PF14362.6 EGE02018.1 - 0.058 12.7 12.4 0.092 12.1 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4551 PF15087.6 EGE02018.1 - 1.1 8.0 9.3 1.5 7.6 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TPMT PF05724.11 EGE02019.1 - 8.7e-29 100.7 0.1 6.3e-28 97.9 0.1 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EGE02019.1 - 1e-06 28.6 0.0 4.2e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02019.1 - 6.8e-05 23.4 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02019.1 - 0.00025 21.7 0.0 0.00045 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02019.1 - 0.0021 17.9 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 EGE02019.1 - 0.065 12.4 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein MFS_1 PF07690.16 EGE02020.1 - 1.8e-47 162.0 38.9 8.9e-38 130.1 25.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE02020.1 - 6.2e-07 28.6 12.8 6.2e-07 28.6 12.8 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGE02020.1 - 0.0011 18.4 5.7 0.0011 18.4 5.7 2.8 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGE02020.1 - 0.0048 15.2 9.5 0.14 10.4 1.7 2.8 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family HC2 PF07382.11 EGE02022.1 - 0.00042 20.4 0.0 0.00042 20.4 0.0 5.3 4 2 0 5 5 5 2 Histone H1-like nucleoprotein HC2 Aldedh PF00171.22 EGE02023.1 - 1.3e-83 281.1 0.0 1.6e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adap_comp_sub PF00928.21 EGE02024.1 - 8.1e-62 209.0 0.0 1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGE02024.1 - 0.00031 20.7 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4536 PF15055.6 EGE02025.1 - 0.0026 18.0 1.3 0.0039 17.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF1636 PF07845.11 EGE02025.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1636) DUF4588 PF15251.6 EGE02026.1 - 6.4e-05 22.8 0.2 6.4e-05 22.8 0.2 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 EGE02027.1 - 2e-75 253.7 0.1 3.7e-75 252.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGE02027.1 - 5.7e-44 148.8 0.9 2.3e-43 146.8 0.9 2.2 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EGE02027.1 - 1.1e-30 106.7 4.8 1.1e-30 106.7 4.8 3.9 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 EGE02027.1 - 6.1e-18 65.2 0.7 2.4e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE02027.1 - 1e-10 41.9 0.9 6.6e-10 39.3 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGE02027.1 - 1.2e-06 27.9 0.1 5.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EGE02027.1 - 0.0003 20.5 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EGE02027.1 - 0.00055 19.7 0.0 0.0015 18.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EGE02027.1 - 0.0021 18.2 0.0 4 7.7 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF1086 PF06461.11 EGE02027.1 - 0.006 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Ku_C PF03730.14 EGE02027.1 - 0.015 16.0 0.4 0.015 16.0 0.4 3.6 4 0 0 4 4 2 0 Ku70/Ku80 C-terminal arm AAA_14 PF13173.6 EGE02027.1 - 0.024 14.7 0.0 0.14 12.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.15 EGE02027.1 - 0.037 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Occludin_ELL PF07303.13 EGE02027.1 - 0.16 12.8 3.2 0.64 10.8 3.2 2.1 1 0 0 1 1 1 0 Occludin homology domain SpoU_methylase PF00588.19 EGE02028.1 - 5.6e-25 88.2 0.0 1.2e-24 87.1 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGE02028.1 - 4.7e-09 36.4 0.0 9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 EGE02029.1 - 5.5e-64 214.9 11.3 1.1e-63 213.8 11.3 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EGE02029.1 - 6.6e-53 179.7 1.6 9.8e-53 179.1 1.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE02029.1 - 4.8e-18 65.5 0.0 1.8e-17 63.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-CCCH_6 PF18585.1 EGE02029.1 - 1.3e-15 57.0 0.9 1.3e-15 57.0 0.9 2.2 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 ResIII PF04851.15 EGE02029.1 - 7.2e-10 39.1 0.0 3.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGE02029.1 - 2.8e-09 36.6 2.5 8.3e-09 35.0 2.5 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 EGE02029.1 - 3.8e-06 26.7 3.1 0.018 15.0 0.5 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 EGE02029.1 - 1.3e-05 25.0 2.6 1.3e-05 25.0 2.6 3.7 2 1 0 2 2 2 1 PHD-finger DEAD PF00270.29 EGE02029.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1087 PF06465.13 EGE02029.1 - 0.0073 16.3 0.6 0.03 14.4 0.1 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) DEAD_2 PF06733.15 EGE02029.1 - 0.021 14.5 0.1 0.089 12.4 0.0 2.1 2 0 0 2 2 2 0 DEAD_2 SnAC PF14619.6 EGE02029.1 - 0.072 13.7 4.9 0.3 11.7 0.4 3.5 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex FANCL_C PF11793.8 EGE02029.1 - 0.62 10.3 3.4 2.4 8.4 3.4 2.1 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 EGE02029.1 - 4.6 7.4 11.6 9.4 6.4 0.3 3.2 3 0 0 3 3 3 0 KIAA1045 RING finger MRP-S28 PF10213.9 EGE02031.1 - 1.5e-40 138.5 0.0 2.4e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 EGE02032.1 - 2.3e-17 63.5 0.1 9.1e-17 61.5 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Actin PF00022.19 EGE02033.1 - 1.2e-125 419.3 0.0 5.1e-125 417.3 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGE02033.1 - 0.17 10.7 0.0 6 5.6 0.0 2.6 3 0 0 3 3 3 0 MreB/Mbl protein DUF3602 PF12223.8 EGE02034.1 - 4.8e-19 68.7 4.3 7.7e-14 52.1 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 EGE02034.1 - 0.19 11.3 4.6 16 5.1 0.3 3.1 1 1 2 3 3 3 0 GTP1/OBG AIDA PF16168.5 EGE02035.1 - 0.0056 16.7 0.1 0.0089 16.1 0.1 1.3 1 0 0 1 1 1 1 Adhesin of bacterial autotransporter system, probable stalk HsbA PF12296.8 EGE02036.1 - 2.3e-10 41.0 0.0 3.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A p450 PF00067.22 EGE02037.1 - 3.4e-58 197.5 0.0 4.3e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-U1 PF06220.12 EGE02038.1 - 6e-06 25.9 0.8 8.3e-06 25.5 0.8 1.2 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.12 EGE02039.1 - 1.2e-166 554.7 28.2 1.5e-166 554.4 28.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGE02039.1 - 1.9e-34 119.0 0.1 3.2e-34 118.3 0.1 1.4 1 0 0 1 1 1 1 ML-like domain APH PF01636.23 EGE02043.1 - 8.4e-12 45.5 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE02043.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EGE02043.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HAD_2 PF13419.6 EGE02044.1 - 6e-15 55.8 0.0 1.8e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE02044.1 - 1.1e-13 52.0 0.0 8.8e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE02044.1 - 1.4e-06 28.3 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EGE02044.1 - 0.0015 18.9 0.0 0.0061 17.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGE02044.1 - 0.022 14.8 0.1 0.2 11.8 0.1 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pollen_Ole_e_I PF01190.17 EGE02045.1 - 0.11 12.8 2.6 0.28 11.6 2.6 1.6 1 0 0 1 1 1 0 Pollen proteins Ole e I like ORMDL PF04061.14 EGE02046.1 - 7.7e-16 58.1 1.4 9e-16 57.9 1.4 1.1 1 0 0 1 1 1 1 ORMDL family DUF2512 PF10710.9 EGE02046.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) PGA2 PF07543.12 EGE02048.1 - 0.5 10.3 6.2 1.3 9.0 5.2 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 CH PF00307.31 EGE02049.1 - 6.3e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGE02049.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin Calponin PF00402.18 EGE02049.1 - 0.17 11.5 5.5 1.1 8.9 1.3 2.7 2 0 0 2 2 2 0 Calponin family repeat NDUFA12 PF05071.16 EGE02050.1 - 2e-10 41.4 10.4 4.5e-09 37.0 10.4 2.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTRF_SDPR PF15237.6 EGE02050.1 - 0.069 12.8 0.2 0.096 12.3 0.2 1.1 1 0 0 1 1 1 0 PTRF/SDPR family DNA_pol_phi PF04931.13 EGE02053.1 - 0.1 10.7 31.9 0.16 10.1 31.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGE02053.1 - 0.17 10.1 25.9 0.22 9.7 25.9 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGE02053.1 - 0.23 9.7 16.5 0.41 8.9 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 EGE02053.1 - 7.5 4.2 7.9 11 3.7 7.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 EGE02053.1 - 8.7 5.0 9.2 15 4.3 9.2 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.12 EGE02056.1 - 0.75 7.7 10.1 1.4 6.8 10.1 1.4 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EMP24_GP25L PF01105.24 EGE02057.1 - 2e-37 128.9 0.0 2.5e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EGE02057.1 - 0.16 10.1 0.3 0.21 9.7 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 EGE02058.1 - 2e-24 85.3 0.2 7e-24 83.6 0.2 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 EGE02059.1 - 2.4e-44 148.4 26.9 1.2e-09 38.7 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE02059.1 - 1.4e-09 38.1 0.6 0.06 13.7 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE02059.1 - 5.2e-05 22.1 8.5 0.1 11.3 0.1 4.7 1 1 4 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGE02059.1 - 0.0019 17.3 0.0 0.9 8.4 0.0 3.7 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGE02059.1 - 0.016 15.2 0.2 20 5.3 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGE02059.1 - 0.02 13.4 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 EGE02059.1 - 0.035 13.5 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain TPR_2 PF07719.17 EGE02060.1 - 0.00018 21.3 5.3 0.76 10.0 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE02060.1 - 0.00026 20.7 4.5 0.15 11.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE02060.1 - 0.00037 20.7 12.9 0.26 11.6 0.1 5.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02060.1 - 0.083 13.1 9.6 0.63 10.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02060.1 - 0.1 13.1 0.6 0.1 13.1 0.6 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Peptidase_M4 PF01447.18 EGE02060.1 - 0.18 12.3 0.1 0.34 11.4 0.1 1.4 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain TPR_7 PF13176.6 EGE02060.1 - 0.26 11.4 9.7 16 5.8 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat SRAP PF02586.14 EGE02061.1 - 2.5e-71 239.7 0.0 3.7e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) MACPF PF01823.19 EGE02064.1 - 4.3e-16 59.6 0.9 6.6e-16 59.0 0.9 1.3 1 0 0 1 1 1 1 MAC/Perforin domain Toxin_10 PF05431.11 EGE02064.1 - 0.035 13.6 0.7 0.078 12.4 0.7 1.5 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DUF1344 PF07076.11 EGE02064.1 - 0.069 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FecR PF04773.13 EGE02064.1 - 0.29 11.8 2.2 0.45 11.2 0.4 2.1 2 0 0 2 2 2 0 FecR protein CBM_19 PF03427.13 EGE02064.1 - 0.53 10.3 3.9 1.5 8.9 3.9 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Ank_2 PF12796.7 EGE02065.1 - 3.6e-07 30.7 0.0 0.0097 16.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE02065.1 - 5.2e-06 26.9 0.1 0.0037 17.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE02065.1 - 0.00043 20.5 0.0 25 5.9 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGE02065.1 - 0.0012 19.1 0.1 0.59 10.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) F-box-like PF12937.7 EGE02065.1 - 0.0093 15.8 0.2 0.022 14.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like Med1 PF10744.9 EGE02066.1 - 1.4e-104 350.5 0.0 1e-76 258.7 0.0 3.0 2 1 1 3 3 3 2 Mediator of RNA polymerase II transcription subunit 1 CPSF100_C PF13299.6 EGE02066.1 - 1.3 9.2 8.0 6.4 6.9 1.2 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal CRA_rpt PF07046.11 EGE02066.1 - 1.9 8.7 5.5 14 6.0 0.9 2.7 2 0 0 2 2 2 0 Cytoplasmic repetitive antigen (CRA) like repeat Gln-synt_C PF00120.24 EGE02067.1 - 3.5e-16 59.1 0.0 4.4e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGE02067.1 - 1.1e-12 47.4 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 EGE02068.1 - 4.3e-29 101.6 38.2 4.3e-29 101.6 38.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGE02068.1 - 0.096 12.4 5.0 0.33 10.7 4.6 1.9 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 AMP-binding PF00501.28 EGE02069.1 - 9.5e-59 199.1 0.0 1.3e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE02069.1 - 0.095 13.7 0.0 0.34 11.9 0.0 2.0 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF3632 PF12311.8 EGE02070.1 - 7e-32 111.3 0.2 9.3e-32 110.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ABC_membrane PF00664.23 EGE02071.1 - 2.5e-75 253.7 32.3 6.3e-42 144.1 12.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE02071.1 - 5.7e-46 156.4 0.2 1.8e-31 109.5 0.0 2.9 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGE02071.1 - 1.7e-07 30.9 0.6 0.00043 19.8 0.1 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGE02071.1 - 2.8e-06 26.4 1.2 0.1 11.4 0.1 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EGE02071.1 - 0.0011 18.6 0.4 0.0028 17.4 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGE02071.1 - 0.0018 18.1 2.1 0.55 10.0 0.4 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGE02071.1 - 0.005 17.1 0.2 0.23 11.7 0.1 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE02071.1 - 0.0085 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGE02071.1 - 0.013 15.8 0.1 0.039 14.3 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 EGE02071.1 - 0.089 13.0 1.4 8.3 6.7 0.1 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EGE02071.1 - 0.14 11.8 0.1 0.32 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain OST3_OST6 PF04756.13 EGE02072.1 - 0.047 13.0 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family APH PF01636.23 EGE02073.1 - 4.7e-08 33.2 0.0 4.8e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGE02073.1 - 5.1e-05 22.6 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase DUF1679 PF07914.11 EGE02073.1 - 0.0011 17.9 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGE02073.1 - 0.057 12.7 0.1 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Strep_SA_rep PF06696.11 EGE02073.1 - 0.072 13.1 1.4 0.36 10.9 0.3 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat tRNA-synt_2b PF00587.25 EGE02074.1 - 6.5e-20 71.8 0.0 2.1e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGE02074.1 - 2.7e-08 34.0 3.2 5.5e-08 33.0 3.2 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EGE02074.1 - 0.0016 17.2 4.9 0.0023 16.6 4.9 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A tRNA-synt_His PF13393.6 EGE02074.1 - 0.014 14.7 1.6 0.51 9.6 1.7 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase FAM184 PF15665.5 EGE02074.1 - 0.044 13.6 3.0 0.091 12.5 3.0 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Flagellar_rod PF05149.12 EGE02074.1 - 0.055 12.9 3.0 0.08 12.4 3.0 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Spc7 PF08317.11 EGE02074.1 - 0.062 12.2 4.8 0.11 11.4 4.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nebulin PF00880.18 EGE02074.1 - 0.14 12.1 0.1 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Nebulin repeat FUSC PF04632.12 EGE02074.1 - 0.2 10.2 0.5 0.28 9.7 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 EGE02074.1 - 0.38 11.1 1.9 7.6 6.9 0.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 EGE02074.1 - 1.2 9.5 7.9 2.3 8.6 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KELK PF15796.5 EGE02074.1 - 1.3 9.5 8.3 1.9 9.0 7.2 1.8 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase JIP_LZII PF16471.5 EGE02074.1 - 1.8 8.8 4.8 25 5.1 0.1 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF2205 PF10224.9 EGE02074.1 - 1.9 8.6 8.6 8.1 6.5 0.3 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DivIC PF04977.15 EGE02074.1 - 8.9 6.2 7.4 5.3 6.9 0.4 2.4 1 1 0 2 2 2 0 Septum formation initiator Cytochrom_B561 PF03188.16 EGE02075.1 - 1.4e-16 60.8 2.1 1.4e-16 60.8 2.1 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGE02075.1 - 0.047 13.8 7.7 0.18 11.9 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2306 PF10067.9 EGE02075.1 - 0.049 13.8 7.1 0.37 11.0 0.6 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF2427 PF10348.9 EGE02075.1 - 0.078 12.8 5.1 0.58 10.0 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.20 EGE02075.1 - 0.085 12.4 7.3 0.46 10.1 5.7 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Bax1-I PF01027.20 EGE02075.1 - 0.12 12.1 13.8 0.16 11.8 6.8 2.3 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4271 PF14093.6 EGE02075.1 - 0.35 10.7 6.7 0.33 10.8 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF1129 PF06570.11 EGE02075.1 - 0.92 9.0 4.9 2 7.8 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2818 PF10993.8 EGE02075.1 - 0.98 10.0 4.6 2.3 8.8 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2818) Allantoicase PF03561.15 EGE02076.1 - 6.5e-88 292.1 0.0 1e-43 148.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.26 EGE02077.1 - 1.9e-31 108.8 0.1 6e-31 107.2 0.0 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGE02077.1 - 8.6e-20 71.0 0.1 2.7e-19 69.4 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGE02077.1 - 3.4e-19 68.7 0.0 1.4e-18 66.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EGE02077.1 - 1.2e-09 38.6 0.0 5.7e-09 36.4 0.0 2.3 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 EGE02077.1 - 1.7e-09 38.3 0.1 1.3e-08 35.5 0.0 2.6 2 0 0 2 2 1 1 AAA ATPase domain GAF PF01590.26 EGE02077.1 - 1.3e-06 29.1 0.0 3.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EGE02077.1 - 5.4e-06 26.0 0.0 8.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.6 EGE02077.1 - 1.9e-05 25.0 0.0 4.6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 EGE02077.1 - 6.6e-05 22.8 0.0 0.00016 21.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.22 EGE02077.1 - 0.00011 21.5 0.0 0.026 13.7 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 EGE02077.1 - 0.019 15.2 0.0 1.3 9.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EGE02077.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_2 PF07719.17 EGE02077.1 - 0.066 13.4 2.8 6.1 7.2 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_35 PF14516.6 EGE02077.1 - 0.091 11.6 0.0 0.28 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.6 EGE02077.1 - 0.15 12.2 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGE02077.1 - 0.17 11.7 0.2 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Response_reg PF00072.24 EGE02079.1 - 2.7e-21 75.8 0.1 5.2e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGE02079.1 - 3e-21 76.0 0.8 9.2e-21 74.5 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGE02079.1 - 8.3e-16 57.8 0.0 2.6e-15 56.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGE02079.1 - 2.3e-11 43.8 1.0 0.00092 19.5 0.1 3.9 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EGE02079.1 - 9.7e-06 25.8 0.2 4.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EGE02079.1 - 0.0026 17.8 3.7 0.34 10.9 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 EGE02079.1 - 0.014 15.6 0.1 6.1 7.1 0.0 3.9 4 0 0 4 4 4 0 PAS domain MotA_ExbB PF01618.16 EGE02079.1 - 0.6 9.9 1.7 0.9 9.3 0.0 2.1 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family F-protein PF00469.20 EGE02079.1 - 4.2 6.9 8.5 9.3 5.8 8.5 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef KxDL PF10241.9 EGE02080.1 - 2.9e-13 49.9 0.1 4e-13 49.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein PspA_IM30 PF04012.12 EGE02080.1 - 0.0036 16.9 2.0 0.0039 16.8 2.0 1.0 1 0 0 1 1 1 1 PspA/IM30 family Fzo_mitofusin PF04799.13 EGE02080.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 fzo-like conserved region AAA PF00004.29 EGE02082.1 - 1.5e-53 180.7 0.0 1.6e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE02082.1 - 1.1e-10 41.1 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGE02082.1 - 6.3e-10 39.7 0.0 0.00099 19.5 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 EGE02082.1 - 1.1e-09 38.0 0.1 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EGE02082.1 - 3.5e-09 37.1 0.0 0.00045 20.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGE02082.1 - 2.8e-08 33.9 0.0 0.0018 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGE02082.1 - 5.3e-08 32.8 0.1 0.0089 15.8 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGE02082.1 - 6.1e-08 33.3 0.0 0.019 15.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain CDC48_N PF02359.18 EGE02082.1 - 8.1e-08 32.3 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 EGE02082.1 - 9.5e-08 31.6 0.0 0.008 15.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGE02082.1 - 1.9e-07 31.1 0.0 0.1 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGE02082.1 - 2.4e-07 30.3 0.1 0.0052 16.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGE02082.1 - 3.3e-07 30.6 0.0 7.7e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGE02082.1 - 1e-06 29.1 0.0 0.07 13.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 EGE02082.1 - 1.3e-06 28.6 0.0 0.035 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGE02082.1 - 5.4e-06 26.3 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EGE02082.1 - 2e-05 24.4 0.0 0.091 12.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EGE02082.1 - 5.1e-05 23.3 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGE02082.1 - 5.2e-05 22.5 0.3 0.11 11.7 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain NACHT PF05729.12 EGE02082.1 - 6.5e-05 22.9 1.7 0.032 14.1 0.0 3.0 3 1 0 3 3 2 1 NACHT domain ATPase PF06745.13 EGE02082.1 - 9.3e-05 21.9 0.6 0.022 14.1 0.2 2.5 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 EGE02082.1 - 9.5e-05 22.0 0.9 0.026 14.0 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EGE02082.1 - 0.0002 21.7 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EGE02082.1 - 0.00036 20.9 0.1 0.19 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGE02082.1 - 0.00039 20.9 0.3 0.055 14.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 EGE02082.1 - 0.00043 19.9 0.2 1.1 8.7 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EGE02082.1 - 0.00043 20.2 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EGE02082.1 - 0.00054 19.8 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGE02082.1 - 0.00074 19.0 0.3 1.4 8.3 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein Sigma54_activat PF00158.26 EGE02082.1 - 0.0008 19.1 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 EGE02082.1 - 0.0011 19.3 0.1 0.57 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGE02082.1 - 0.0011 18.7 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EGE02082.1 - 0.0035 16.7 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EGE02082.1 - 0.0047 16.1 0.0 0.47 9.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EGE02082.1 - 0.0053 16.7 0.5 16 5.3 0.0 3.3 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGE02082.1 - 0.014 15.3 0.1 8.3 6.3 0.0 2.9 3 0 0 3 3 2 0 NTPase ResIII PF04851.15 EGE02082.1 - 0.017 15.1 0.0 5.4 7.0 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EGE02082.1 - 0.023 14.0 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 EGE02082.1 - 0.028 13.9 0.1 2 7.8 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TniB PF05621.11 EGE02082.1 - 0.033 13.6 0.1 4.3 6.7 0.1 3.2 3 1 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 EGE02082.1 - 0.06 13.3 0.0 0.24 11.4 0.0 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DAP3 PF10236.9 EGE02082.1 - 0.081 12.1 0.4 21 4.1 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SRP54 PF00448.22 EGE02082.1 - 0.088 12.4 0.2 6 6.4 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain IPT PF01745.16 EGE02082.1 - 0.12 11.7 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_29 PF13555.6 EGE02082.1 - 0.14 11.9 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cir_N PF10197.9 EGE02083.1 - 1.6e-06 28.2 8.4 1.6e-06 28.2 8.4 5.5 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_25 PF13649.6 EGE02084.1 - 4e-10 40.3 0.0 1.2e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGE02084.1 - 7.3e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGE02084.1 - 2e-08 34.8 0.0 4.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02084.1 - 4.1e-08 33.2 0.0 7.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02084.1 - 1.6e-05 24.8 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGE02084.1 - 3.9e-05 23.6 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE02084.1 - 0.00025 20.6 0.1 0.00044 19.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EGE02084.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EGE02084.1 - 0.0098 16.6 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RasGAP_C PF03836.15 EGE02084.1 - 0.014 15.6 0.4 0.027 14.6 0.4 1.4 1 0 0 1 1 1 0 RasGAP C-terminus TehB PF03848.14 EGE02084.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 EGE02084.1 - 0.028 13.7 0.0 0.15 11.3 0.0 2.1 3 0 0 3 3 3 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGE02084.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGE02084.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EGE02084.1 - 0.1 13.6 0.0 0.28 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGE02084.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGE02084.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Mo25 PF08569.11 EGE02085.1 - 4.5e-133 443.7 0.0 5.1e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Mo25-like TPP_enzyme_N PF02776.18 EGE02086.1 - 3.6e-40 137.4 0.0 6.6e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGE02086.1 - 1.2e-17 64.1 0.0 4.6e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGE02086.1 - 3.3e-14 52.8 0.0 6.1e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain RabGAP-TBC PF00566.18 EGE02087.1 - 7.3e-35 120.6 0.0 1.2e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DPCD PF14913.6 EGE02087.1 - 0.015 14.6 0.2 0.033 13.5 0.2 1.5 1 0 0 1 1 1 0 DPCD protein family Limkain-b1 PF11608.8 EGE02087.1 - 0.095 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Limkain b1 SKG6 PF08693.10 EGE02088.1 - 3.7e-06 26.2 0.3 6.7e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BTB PF00651.31 EGE02089.1 - 1.2e-17 64.1 0.1 1.7e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF456 PF04306.13 EGE02091.1 - 0.058 13.7 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) MSSP PF03940.13 EGE02091.1 - 0.066 12.8 1.1 0.096 12.3 0.0 1.8 2 0 0 2 2 2 0 Male specific sperm protein LRS4 PF10422.9 EGE02091.1 - 0.12 11.9 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ORC4_C PF14629.6 EGE02092.1 - 2.5e-43 148.0 0.0 4.1e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EGE02092.1 - 1.6e-17 64.4 0.3 4.4e-17 63.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGE02092.1 - 2.8e-05 24.4 0.0 7.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGE02092.1 - 0.00018 20.7 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 EGE02092.1 - 0.00066 20.1 0.0 0.0026 18.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGE02092.1 - 0.0014 19.0 0.2 0.0038 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGE02092.1 - 0.011 15.7 0.1 0.05 13.5 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EGE02092.1 - 0.027 14.5 0.0 0.061 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGE02092.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3439 PF11921.8 EGE02092.1 - 3.3 7.7 6.8 9.4 6.2 6.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SET PF00856.28 EGE02093.1 - 1.1e-06 29.1 4.2 4.1e-06 27.3 0.7 3.0 2 1 0 2 2 2 1 SET domain PHD PF00628.29 EGE02093.1 - 5.5e-06 26.2 9.6 1.3e-05 24.9 9.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGE02093.1 - 0.44 10.1 5.4 0.85 9.2 5.4 1.5 1 0 0 1 1 1 0 PHD-finger ArfGap PF01412.18 EGE02094.1 - 1.3e-36 125.2 0.0 2.6e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.17 EGE02095.1 - 1.7e-76 258.1 13.4 2.2e-76 257.8 13.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 EGE02096.1 - 4.9e-116 387.7 0.0 5.7e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EGE02096.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.23 EGE02097.1 - 6.4e-64 216.2 34.1 3.2e-40 138.5 19.4 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EGE02097.1 - 3.3e-47 160.4 0.9 5.6e-27 94.9 0.2 3.5 3 0 0 3 3 3 2 ABC transporter MMR_HSR1 PF01926.23 EGE02097.1 - 2.6e-06 27.5 0.8 0.02 15.0 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EGE02097.1 - 3.9e-05 23.2 6.4 0.13 11.7 2.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGE02097.1 - 4e-05 23.6 1.1 0.27 11.0 0.1 3.7 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGE02097.1 - 7.8e-05 23.1 0.3 0.29 11.5 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGE02097.1 - 0.0001 22.3 0.2 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGE02097.1 - 0.00028 21.4 0.9 0.32 11.5 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EGE02097.1 - 0.00054 19.7 1.3 0.39 10.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGE02097.1 - 0.0017 17.7 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 EGE02097.1 - 0.0027 16.7 2.1 0.5 9.3 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGE02097.1 - 0.0036 17.4 2.2 0.24 11.5 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 EGE02097.1 - 0.012 15.4 0.4 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGE02097.1 - 0.014 15.7 0.5 4.9 7.4 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EGE02097.1 - 0.037 14.6 0.0 5.4 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGE02097.1 - 0.047 13.8 3.9 0.12 12.5 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EGE02097.1 - 0.056 13.2 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGE02097.1 - 0.094 12.4 2.2 3.1 7.5 0.2 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGE02097.1 - 0.15 12.3 0.1 27 5.0 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EGE02097.1 - 0.16 11.9 0.8 21 5.0 0.1 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EGE02097.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.8 4 0 0 4 4 2 0 AAA domain NB-ARC PF00931.22 EGE02097.1 - 0.57 9.3 2.1 13 4.9 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain AA_permease_2 PF13520.6 EGE02098.1 - 8.3e-45 153.4 45.6 2.4e-44 151.9 43.7 2.1 1 1 0 1 1 1 1 Amino acid permease Tyr-DNA_phospho PF06087.12 EGE02099.1 - 3.1e-163 543.6 0.0 3.6e-163 543.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGE02099.1 - 0.0037 17.2 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain ACBP PF00887.19 EGE02100.1 - 3e-19 69.0 0.5 3.9e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.15 EGE02101.1 - 3.6e-24 84.7 0.1 6.9e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.6 EGE02101.1 - 4.4e-09 35.9 1.0 1.1e-08 34.6 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EGE02101.1 - 1.8e-08 33.9 3.6 0.0002 21.2 1.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02101.1 - 2.1e-07 31.5 1.2 0.00013 22.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE02101.1 - 1.4e-06 27.8 2.9 8.5e-05 22.2 1.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02101.1 - 2.5e-06 27.9 0.2 0.0012 19.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EGE02101.1 - 7e-06 26.7 5.5 1.2e-05 25.9 5.5 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_12 PF13424.6 EGE02101.1 - 4.1e-05 23.8 1.7 0.014 15.6 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE02101.1 - 0.001 19.7 0.0 0.47 11.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-Nse PF11789.8 EGE02101.1 - 0.0029 17.4 0.1 0.0095 15.7 0.1 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGE02101.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger TPR_17 PF13431.6 EGE02101.1 - 0.011 16.1 2.4 0.092 13.2 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 EGE02101.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein FCH PF00611.23 EGE02101.1 - 0.031 14.6 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TPR_10 PF13374.6 EGE02101.1 - 0.037 13.9 0.3 16 5.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE02101.1 - 0.047 13.9 0.1 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TIM PF00121.18 EGE02104.1 - 5.9e-41 140.4 0.0 1.4e-40 139.2 0.0 1.6 1 1 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 EGE02105.1 - 1.9e-43 147.8 0.1 2.2e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EGE02105.1 - 0.032 14.4 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2620 DHO_dh PF01180.21 EGE02106.1 - 4.8e-61 206.6 0.1 5.7e-61 206.3 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EGE02106.1 - 0.0015 17.6 0.9 0.0034 16.5 0.9 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PcrB PF01884.17 EGE02106.1 - 0.3 10.5 2.1 2.8 7.3 0.1 2.3 1 1 1 2 2 2 0 PcrB family Mnd1 PF03962.15 EGE02107.1 - 1.7e-21 76.3 0.1 7.4e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGE02107.1 - 0.00055 20.0 0.3 0.0022 18.1 0.3 2.0 1 0 0 1 1 1 1 Leucine zipper with capping helix domain DUF5395 PF17373.2 EGE02107.1 - 0.048 14.3 0.2 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5395) HTH_38 PF13936.6 EGE02107.1 - 0.1 12.4 0.7 13 5.6 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain BRE1 PF08647.11 EGE02107.1 - 0.18 11.9 13.4 1.6 8.8 8.2 3.4 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 EGE02107.1 - 0.83 9.5 16.1 0.8 9.5 2.1 3.5 2 1 2 4 4 4 0 Septum formation initiator DUF1843 PF08898.10 EGE02107.1 - 0.84 10.2 4.0 8.8 6.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) BBS2_C PF14782.6 EGE02107.1 - 1.8 7.3 5.6 0.5 9.1 1.6 1.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal SlyX PF04102.12 EGE02107.1 - 4.3 8.0 6.3 20 5.9 1.3 3.1 2 1 0 2 2 2 0 SlyX Fib_alpha PF08702.10 EGE02107.1 - 6.3 7.0 8.0 1.1 9.4 3.4 2.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family UAF_Rrn10 PF05234.11 EGE02108.1 - 6.2e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 EGE02109.1 - 2e-15 56.9 18.9 1.2e-05 25.9 0.5 6.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE02109.1 - 1.5e-08 34.8 0.1 0.0062 16.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 EGE02110.1 - 1.9e-94 316.7 0.2 2.5e-94 316.3 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02110.1 - 1.3e-06 28.4 8.8 2.6e-06 27.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PH PF00169.29 EGE02115.1 - 7.2e-08 32.9 0.3 3.1e-07 30.9 0.3 2.1 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 EGE02115.1 - 0.069 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain zf-H2C2_2 PF13465.6 EGE02118.1 - 4.3e-06 26.9 12.6 1.2e-05 25.6 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 EGE02118.1 - 0.0001 22.5 4.6 0.0002 21.6 4.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EGE02118.1 - 0.00011 22.7 15.0 0.013 16.3 5.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE02118.1 - 0.00084 19.6 4.8 0.058 13.7 1.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGE02118.1 - 0.017 15.6 14.5 0.085 13.3 7.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EGE02118.1 - 0.36 11.3 5.0 3.1 8.3 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type QCR10 PF09796.9 EGE02119.1 - 5.2e-27 93.7 0.1 6.8e-27 93.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) APG5 PF04106.12 EGE02120.1 - 2e-68 230.4 0.0 2.4e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SelP_N PF04592.14 EGE02121.1 - 0.56 9.6 15.3 0.76 9.1 15.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 EGE02121.1 - 0.99 8.1 3.3 1.1 8.0 3.3 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGE02121.1 - 5.2 5.5 13.6 6.4 5.2 13.6 1.1 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 EGE02121.1 - 7.6 5.8 6.1 9.8 5.4 6.1 1.1 1 0 0 1 1 1 0 FAM76 protein MFS_1 PF07690.16 EGE02122.1 - 2.1e-18 66.4 55.5 2.2e-17 63.0 50.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Arrestin_C PF02752.22 EGE02127.1 - 0.0017 18.8 0.0 0.0059 17.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Helo_like_N PF17111.5 EGE02128.1 - 7.8e-05 22.1 2.3 0.00013 21.4 2.3 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SHR3_chaperone PF08229.11 EGE02129.1 - 3.9e-82 273.8 0.0 5.3e-82 273.4 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Phage_holin_2_4 PF16082.5 EGE02129.1 - 0.12 12.1 3.4 0.15 11.8 1.6 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Peptidase_M28 PF04389.17 EGE02134.1 - 1.1e-33 116.6 0.3 1.7e-33 116.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGE02134.1 - 0.00024 20.9 0.1 0.0004 20.1 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4317 PF14199.6 EGE02134.1 - 0.028 13.6 0.1 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Glyco_hydro81C PF17652.1 EGE02135.1 - 3.7e-164 546.1 3.1 4.7e-164 545.7 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EGE02135.1 - 5.5e-120 400.4 0.2 7.8e-120 399.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 EGE02137.1 - 3e-128 429.5 52.8 5.6e-118 395.6 45.4 3.5 1 1 2 3 3 3 2 Utp14 protein MRP-L27 PF09809.9 EGE02138.1 - 1.6e-12 47.2 0.2 2.1e-12 46.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HECT PF00632.25 EGE02139.1 - 2.1e-82 277.1 0.0 3.9e-82 276.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EGE02139.1 - 0.0087 15.8 0.2 0.037 13.8 0.2 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif RRM_1 PF00076.22 EGE02140.1 - 2.6e-80 264.2 5.2 5.7e-22 77.3 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGE02140.1 - 1.1e-26 92.7 0.1 5.5e-26 90.6 0.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGE02140.1 - 4.3e-14 52.2 0.1 0.014 15.0 0.0 5.3 2 1 2 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE02140.1 - 8.7e-07 29.0 0.4 5.2 7.3 0.0 5.4 5 1 0 5 5 5 2 RNA recognition motif RRM_occluded PF16842.5 EGE02140.1 - 6.5e-06 25.9 0.0 0.017 15.0 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGE02140.1 - 0.0011 18.9 0.3 39 4.4 0.0 4.7 5 0 0 5 5 5 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGE02140.1 - 0.012 15.6 15.4 0.17 11.9 2.2 5.0 4 1 1 5 5 5 0 RNA binding motif Limkain-b1 PF11608.8 EGE02140.1 - 0.014 15.4 1.0 4.3 7.5 0.0 3.5 3 0 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 EGE02140.1 - 0.11 12.2 1.8 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 EGE02140.1 - 0.23 12.0 7.3 1.4 9.5 0.9 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT NPR3 PF03666.13 EGE02140.1 - 0.84 8.4 5.5 1.3 7.7 5.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RNA_pol_Rpc4 PF05132.14 EGE02140.1 - 1.3 9.5 12.6 6.1 7.3 9.3 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Fe-ADH PF00465.19 EGE02141.1 - 5e-67 226.3 0.7 6e-67 226.0 0.7 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGE02141.1 - 3.5e-18 66.2 0.0 6.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EGE02141.1 - 0.011 14.9 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 3-dehydroquinate synthase PFK PF00365.20 EGE02141.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphofructokinase Sigma54_activ_2 PF14532.6 EGE02141.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DAO PF01266.24 EGE02142.1 - 1.8e-61 208.7 0.0 2e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGE02142.1 - 0.00013 21.5 0.1 0.00018 21.0 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE02142.1 - 0.00023 21.3 0.7 0.00046 20.4 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE02142.1 - 0.0055 16.0 0.0 0.014 14.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE02142.1 - 0.0096 15.2 0.5 0.035 13.4 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGE02142.1 - 0.012 14.9 0.3 0.03 13.6 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EGE02142.1 - 0.026 15.1 0.3 0.051 14.1 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE02142.1 - 0.032 14.2 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EGE02142.1 - 0.085 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EGE02142.1 - 0.17 11.8 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EGE02142.1 - 0.19 10.9 0.1 0.78 8.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGE02142.1 - 0.23 10.5 2.3 0.43 9.6 2.3 1.3 1 0 0 1 1 1 0 FAD binding domain Vps52 PF04129.12 EGE02143.1 - 2.8e-123 412.3 3.0 3.6e-123 412.0 3.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGE02143.1 - 6.8e-07 28.1 5.4 9.6e-07 27.6 5.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 MitMem_reg PF13012.6 EGE02143.1 - 0.00032 21.1 0.5 0.048 14.1 0.4 3.4 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function SecA_SW PF07516.13 EGE02143.1 - 0.092 12.8 0.4 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 SecA Wing and Scaffold domain COG2 PF06148.11 EGE02143.1 - 0.12 12.5 1.1 0.23 11.6 0.1 2.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 eIF-5a PF01287.20 EGE02144.1 - 1.7e-27 95.3 0.6 2.4e-27 94.8 0.6 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold zf-RRN7 PF11781.8 EGE02145.1 - 1.9e-06 27.4 6.0 3.5e-06 26.6 6.0 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tli4_C PF18426.1 EGE02145.1 - 0.0083 16.5 0.4 0.017 15.5 0.4 1.5 1 0 0 1 1 1 1 Tle cognate immunity protein 4 C-terminal domain Ribosomal_L40e PF01020.17 EGE02146.1 - 3.8e-31 106.7 11.0 5.1e-31 106.3 11.0 1.2 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 EGE02146.1 - 1.7e-20 72.5 0.0 2.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGE02146.1 - 3.5e-07 30.0 0.0 4.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Yip1 PF04893.17 EGE02147.1 - 7.7e-11 42.0 17.2 1.7e-10 40.9 17.2 1.6 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EGE02147.1 - 0.024 14.2 2.4 0.28 10.7 2.7 2.1 2 0 0 2 2 2 0 YIF1 DUF5585 PF17823.1 EGE02147.1 - 0.31 9.9 0.1 0.44 9.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) RabGAP-TBC PF00566.18 EGE02148.1 - 6.9e-23 81.4 0.1 1.6e-22 80.2 0.2 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EGE02150.1 - 6.1e-90 302.2 0.0 1.1e-89 301.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGE02150.1 - 0.0018 17.7 0.0 0.0073 15.7 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region Lgl_C PF08596.10 EGE02150.1 - 0.17 10.5 0.0 6.2 5.4 0.0 2.7 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal GTP_EFTU PF00009.27 EGE02151.1 - 3.4e-34 118.1 0.1 4.6e-33 114.4 0.1 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGE02151.1 - 6.6e-21 74.4 0.1 1.9e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGE02151.1 - 5.2e-11 42.8 0.5 7.1e-10 39.1 0.1 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGE02151.1 - 2e-09 37.2 0.0 6.4e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EGE02151.1 - 4.8e-07 29.9 0.5 9.3e-06 25.7 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGE02151.1 - 0.0005 20.3 0.0 0.0017 18.6 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGE02151.1 - 0.0051 16.6 0.0 0.025 14.4 0.0 2.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EGE02151.1 - 0.041 13.5 0.0 0.22 11.1 0.0 2.4 1 1 0 1 1 1 0 Ras family DUF936 PF06075.12 EGE02151.1 - 0.21 10.5 39.0 0.32 9.8 39.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Rhodanese PF00581.20 EGE02152.1 - 2.3e-09 37.8 0.0 5.5e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain p450 PF00067.22 EGE02153.1 - 2.9e-53 181.2 0.0 4.1e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_6 PF18029.1 EGE02154.1 - 0.00024 21.9 0.1 0.00045 21.0 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGE02154.1 - 0.0047 17.1 0.0 0.048 13.8 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-HC2 PF13490.6 EGE02154.1 - 0.15 12.4 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative zinc-finger SRP68 PF16969.5 EGE02155.1 - 2.9e-184 614.2 0.4 3.2e-184 614.0 0.4 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 CENP-O PF09496.10 EGE02155.1 - 0.26 11.3 1.2 3.8 7.4 0.0 2.9 2 1 1 3 3 3 0 Cenp-O kinetochore centromere component PPR PF01535.20 EGE02156.1 - 8.8e-17 60.1 6.0 4e-05 23.6 0.0 7.6 7 0 0 7 7 7 5 PPR repeat PPR_2 PF13041.6 EGE02156.1 - 1.6e-15 57.0 7.7 5.7e-09 36.0 0.0 5.8 4 1 2 6 6 6 2 PPR repeat family PPR_3 PF13812.6 EGE02156.1 - 6.3e-15 55.0 1.9 1.2e-05 25.3 0.0 4.7 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGE02156.1 - 8e-07 28.6 0.0 3.9e-06 26.4 0.0 2.4 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGE02156.1 - 4.4e-05 23.1 0.8 10 5.9 0.1 5.5 6 0 0 6 6 6 2 PPR repeat MLTR_LBD PF17765.1 EGE02156.1 - 0.16 12.1 0.8 5.9 7.0 0.0 2.8 3 0 0 3 3 3 0 MmyB-like transcription regulator ligand binding domain MCM PF00493.23 EGE02157.1 - 1e-97 325.7 0.1 1.8e-97 324.9 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGE02157.1 - 3.3e-31 107.7 0.0 7.4e-31 106.6 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGE02157.1 - 2.8e-24 85.3 0.8 9.7e-24 83.6 0.6 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGE02157.1 - 1.5e-12 48.0 0.0 4.4e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE02157.1 - 1.3e-06 28.0 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGE02157.1 - 0.003 17.4 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGE02157.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Spo7 PF03907.13 EGE02158.1 - 1.4e-89 299.4 0.0 2.1e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein YL1 PF05764.13 EGE02158.1 - 0.13 12.4 5.8 0.29 11.2 5.8 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Abhydrolase_1 PF00561.20 EGE02159.1 - 1.6e-20 73.8 0.0 4.1e-18 65.9 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE02159.1 - 5.9e-16 58.5 0.0 3e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE02159.1 - 6e-16 59.7 0.3 5.2e-15 56.7 0.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGE02159.1 - 8.8e-05 22.3 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EGE02159.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EGE02159.1 - 0.0031 17.1 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EGE02159.1 - 0.0065 15.4 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGE02159.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_3 PF07859.13 EGE02159.1 - 0.021 14.7 0.0 0.084 12.7 0.0 2.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGE02159.1 - 0.026 14.3 0.0 4.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EGE02159.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EGE02159.1 - 0.034 14.3 0.3 0.21 11.7 0.3 2.2 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 EGE02159.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 EGE02159.1 - 0.11 12.0 0.0 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Herpes_pp85 PF04637.12 EGE02159.1 - 8.3 4.7 5.4 13 4.1 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TatD_DNase PF01026.21 EGE02160.1 - 1.4e-37 129.4 0.0 2.4e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TPP_enzyme_N PF02776.18 EGE02161.1 - 5.4e-39 133.5 0.1 3.1e-38 131.1 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGE02161.1 - 6.6e-21 74.7 0.1 1.3e-20 73.8 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGE02161.1 - 1.6e-13 50.6 0.0 2e-12 47.0 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 EGE02161.1 - 0.033 14.6 0.6 1.3 9.4 0.6 3.0 1 1 0 1 1 1 0 MobA-like NTP transferase domain Chitin_synth_2 PF03142.15 EGE02162.1 - 2.1e-229 762.5 0.1 3.1e-229 762.0 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 EGE02162.1 - 4.6e-17 61.7 0.3 1.7e-16 59.9 0.4 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGE02162.1 - 1e-12 48.4 4.4 2.1e-12 47.4 4.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 EGE02162.1 - 2.7e-12 46.7 0.5 4.2e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EGE02162.1 - 3.9e-12 46.6 0.1 3.8e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EGE02162.1 - 2.8e-09 35.8 0.0 3e-07 29.1 0.0 2.1 1 1 0 2 2 2 2 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EGE02162.1 - 0.00014 21.4 0.0 0.0077 15.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGE02162.1 - 0.001 18.9 0.0 0.41 10.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 EGE02165.1 - 1.6e-246 819.0 0.7 2.3e-246 818.5 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EGE02165.1 - 1.1e-72 245.3 0.0 8e-72 242.5 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EGE02165.1 - 5.5e-19 68.1 0.4 4e-14 52.5 0.1 3.6 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EGE02165.1 - 5e-15 55.2 0.4 1.3e-14 53.9 0.4 1.7 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EGE02165.1 - 4.2e-13 49.7 5.0 1.1e-12 48.3 5.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGE02165.1 - 1.2e-10 41.7 0.1 1e-09 38.7 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGE02165.1 - 0.00026 20.9 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGE02165.1 - 0.0023 17.5 0.2 0.029 13.8 0.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 RsgA_GTPase PF03193.16 EGE02165.1 - 0.017 15.0 0.0 0.33 10.9 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGE02165.1 - 0.056 13.8 0.2 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain KH_1 PF00013.29 EGE02166.1 - 5.5e-27 93.4 1.6 1.7e-05 24.6 0.1 7.0 7 0 0 7 7 7 6 KH domain Ribosomal_S6 PF01250.17 EGE02166.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S6 SUV3_C PF12513.8 EGE02166.1 - 0.13 12.3 0.1 0.38 10.7 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal Hydrolase PF00702.26 EGE02167.1 - 4.7e-08 33.6 0.0 6.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGE02167.1 - 9.5e-08 32.3 0.0 1.5e-07 31.7 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE02167.1 - 0.0095 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Dynactin PF12455.8 EGE02169.1 - 4e-85 285.5 4.6 4e-85 285.5 4.6 4.3 2 2 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 EGE02169.1 - 2e-20 72.6 0.1 3.3e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain APG6_N PF17675.1 EGE02169.1 - 0.053 14.1 0.2 0.053 14.1 0.2 8.4 5 2 4 9 9 9 0 Apg6 coiled-coil region HALZ PF02183.18 EGE02169.1 - 0.21 11.9 0.1 0.21 11.9 0.1 7.6 6 1 2 8 8 8 0 Homeobox associated leucine zipper Beta_elim_lyase PF01212.21 EGE02170.1 - 8e-84 281.4 0.0 9.7e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EGE02170.1 - 1.2e-07 31.2 0.0 1.9e-07 30.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGE02170.1 - 8.7e-06 24.9 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGE02170.1 - 0.0078 14.8 0.0 0.015 13.9 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EGE02170.1 - 0.039 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EGE02170.1 - 0.051 12.9 0.1 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Solute_trans_a PF03619.16 EGE02172.1 - 1.2e-91 307.0 9.4 1.5e-91 306.6 9.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Podoplanin PF05808.11 EGE02172.1 - 0.94 9.6 2.3 1.7 8.7 2.3 1.4 1 0 0 1 1 1 0 Podoplanin Glyco_hyd_65N_2 PF14498.6 EGE02173.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain GTP_EFTU PF00009.27 EGE02174.1 - 4.1e-67 225.5 0.2 5.5e-67 225.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGE02174.1 - 5.3e-30 103.7 0.0 3.3e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGE02174.1 - 2.8e-21 75.3 0.0 1e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGE02174.1 - 3.4e-13 49.8 0.1 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGE02174.1 - 5.1e-12 45.7 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGE02174.1 - 9.8e-05 22.4 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWI PF01480.17 EGE02175.1 - 6.6e-10 39.2 0.1 1.4e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EGE02175.1 - 1.3e-07 31.3 0.1 2e-05 24.3 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE02175.1 - 2.3e-06 27.5 0.0 7e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGE02175.1 - 0.00051 19.9 1.1 0.00088 19.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE02175.1 - 0.013 15.5 1.4 0.024 14.7 1.4 1.4 1 0 0 1 1 1 0 Zinc finger domain RRM_occluded PF16842.5 EGE02175.1 - 0.016 15.0 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif UPF0242 PF06785.11 EGE02175.1 - 0.21 11.7 5.5 0.36 10.9 5.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TipAS PF07739.13 EGE02175.1 - 1.5 9.4 8.3 13 6.4 0.1 2.6 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain RRM_3 PF08777.11 EGE02175.1 - 7.3 6.7 9.6 2.1 8.4 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif adh_short PF00106.25 EGE02176.1 - 4e-13 49.3 0.0 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE02176.1 - 8.4e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 EGE02177.1 - 1.6e-41 142.4 16.0 5.1e-41 140.8 16.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE02177.1 - 5.4e-10 38.7 11.9 1e-09 37.8 11.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGE02177.1 - 1.4e-05 24.6 13.0 0.0006 19.2 13.0 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGE02177.1 - 0.00013 20.9 5.9 0.00013 20.9 5.9 1.6 1 1 0 1 1 1 1 MFS_1 like family DctQ PF04290.12 EGE02177.1 - 0.004 17.1 0.0 0.004 17.1 0.0 2.8 2 2 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4131 PF13567.6 EGE02177.1 - 0.007 16.0 2.4 2.7 7.6 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) CitMHS PF03600.16 EGE02177.1 - 0.14 11.3 17.8 1 8.5 8.7 2.2 1 1 1 2 2 2 0 Citrate transporter RIBIOP_C PF04950.12 EGE02180.1 - 7.3e-96 321.0 0.0 7.3e-96 321.0 0.0 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGE02180.1 - 9.5e-29 99.3 0.0 2.4e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EGE02180.1 - 3.3e-05 24.2 0.2 9.6e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 EGE02180.1 - 5.6e-05 22.8 0.0 0.0085 15.6 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EGE02180.1 - 0.00017 22.0 0.0 0.00044 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE02180.1 - 0.00022 21.7 0.0 0.0007 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGE02180.1 - 0.0013 18.8 0.0 0.0041 17.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EGE02180.1 - 0.0026 17.0 0.0 0.0061 15.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EGE02180.1 - 0.004 16.7 0.0 0.0078 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 EGE02180.1 - 0.0052 16.5 0.0 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGE02180.1 - 0.0058 17.2 3.2 0.034 14.7 0.2 3.3 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 EGE02180.1 - 0.0081 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGE02180.1 - 0.0083 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EGE02180.1 - 0.016 15.2 0.4 0.031 14.2 0.4 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EGE02180.1 - 0.017 15.6 1.7 0.033 14.7 0.1 2.3 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.6 EGE02180.1 - 0.031 14.4 0.0 0.031 14.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 EGE02180.1 - 0.041 14.2 0.2 0.093 13.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGE02180.1 - 0.043 13.7 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGE02180.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGE02180.1 - 0.047 13.6 1.3 0.073 13.0 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 EGE02180.1 - 0.054 13.7 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EGE02180.1 - 0.059 13.4 0.2 0.19 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGE02180.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGE02180.1 - 0.073 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.15 EGE02180.1 - 0.083 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain MobB PF03205.14 EGE02180.1 - 0.089 12.7 0.1 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EGE02180.1 - 0.1 12.5 0.1 0.36 10.7 0.1 1.8 1 1 1 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EGE02180.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 EGE02180.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EGE02180.1 - 0.24 11.2 0.0 0.24 11.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain KCNQC3-Ank-G_bd PF11956.8 EGE02180.1 - 4.2 7.7 9.1 0.053 13.8 0.6 2.2 2 0 0 2 2 1 0 Ankyrin-G binding motif of KCNQ2-3 Aminotran_1_2 PF00155.21 EGE02181.1 - 1.9e-38 132.6 0.0 2.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SDA1 PF05285.12 EGE02183.1 - 0.068 12.6 9.5 0.12 11.8 9.5 1.5 1 0 0 1 1 1 0 SDA1 IMUP PF15761.5 EGE02183.1 - 1.5 9.6 4.8 2.1 9.0 1.5 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF1989 PF09347.10 EGE02185.1 - 3.8e-65 218.6 0.0 4.6e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Abhydrolase_1 PF00561.20 EGE02186.1 - 4e-13 49.6 0.0 6.5e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE02186.1 - 7.1e-11 43.1 0.0 9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE02186.1 - 6.5e-09 35.4 0.0 1.6e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3425 PF11905.8 EGE02187.1 - 1.3e-10 41.3 1.8 8.5e-09 35.4 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EGE02187.1 - 0.062 13.4 8.8 0.11 12.5 8.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EGE02187.1 - 0.18 11.9 7.0 0.37 10.9 7.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper BCDHK_Adom3 PF10436.9 EGE02190.1 - 5e-46 156.5 0.1 7.5e-46 155.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EGE02190.1 - 5.2e-09 36.6 0.0 2.4e-08 34.5 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EGE02190.1 - 0.031 14.2 0.0 0.089 12.8 0.0 1.7 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Saf_2TM PF18303.1 EGE02191.1 - 0.98 9.0 4.7 0.51 9.9 0.4 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF2157 PF09925.9 EGE02191.1 - 2.5 7.9 8.9 0.094 12.5 0.7 2.6 1 1 1 3 3 3 0 Predicted membrane protein (DUF2157) DUF3397 PF11877.8 EGE02191.1 - 7.4 6.8 15.5 0.29 11.4 2.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3397) Lactamase_B_2 PF12706.7 EGE02192.1 - 2.5e-14 53.3 0.2 4.7e-14 52.4 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGE02192.1 - 3.4e-10 40.1 1.8 2.4e-09 37.3 1.8 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.26 EGE02193.1 - 4.3e-60 203.4 1.6 2.6e-59 200.9 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGE02193.1 - 7.1e-35 119.6 0.4 1.4e-34 118.6 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGE02193.1 - 6.8e-06 25.6 2.2 0.00021 20.8 0.2 2.6 3 0 0 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE02193.1 - 0.02 14.6 3.5 0.035 13.8 0.3 2.8 3 1 0 3 3 3 0 Thiolase, C-terminal domain Arginase PF00491.21 EGE02194.1 - 6.7e-87 291.5 0.2 8.2e-87 291.2 0.2 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EGE02194.1 - 0.0032 17.7 0.1 0.0063 16.8 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 EGE02195.1 - 5.6e-44 149.6 0.0 6.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE02195.1 - 2.8e-19 69.5 0.0 3.5e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE02195.1 - 1.8e-05 24.3 0.0 2.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1349 PF07081.11 EGE02196.1 - 1.1e-30 106.7 0.0 9.8e-30 103.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) MFS_1 PF07690.16 EGE02197.1 - 4.9e-21 75.0 39.2 8.7e-20 70.9 39.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM100 PF16311.5 EGE02197.1 - 2.7 7.6 4.8 8.2 6.0 1.2 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 DUF2530 PF10745.9 EGE02197.1 - 5.8 7.2 8.2 1.1 9.6 0.9 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2530) p450 PF00067.22 EGE02198.1 - 2.7e-47 161.6 0.0 3.6e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAPRTase PF04095.16 EGE02198.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Vint PF14623.6 EGE02199.1 - 1.4e-60 203.9 0.0 3.6e-60 202.6 0.0 1.7 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EGE02199.1 - 4e-25 87.7 0.0 7.2e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 EGE02199.1 - 1.1e-17 64.9 0.0 2e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGE02199.1 - 1.3e-13 51.6 0.0 2.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGE02199.1 - 1.4e-12 47.8 0.0 1.3e-09 38.1 0.0 3.1 2 1 0 2 2 2 2 von Willebrand factor type A domain ABC_membrane PF00664.23 EGE02200.1 - 8.8e-104 347.0 25.6 6.6e-55 186.7 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE02200.1 - 3.7e-67 225.0 0.0 7e-33 114.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE02200.1 - 8.5e-14 51.5 0.3 0.00011 21.7 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE02200.1 - 1.1e-06 28.9 0.3 0.11 12.7 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGE02200.1 - 3.9e-06 26.5 4.9 0.0012 18.6 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE02200.1 - 5.2e-06 26.9 1.3 0.12 12.7 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGE02200.1 - 7.3e-06 26.0 0.2 0.12 12.2 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_21 PF13304.6 EGE02200.1 - 2.3e-05 24.4 0.4 0.3 10.9 0.0 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGE02200.1 - 9e-05 22.3 0.8 0.72 9.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGE02200.1 - 0.00014 22.4 0.0 0.18 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EGE02200.1 - 0.0002 20.3 0.5 0.77 8.5 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 EGE02200.1 - 0.00045 20.2 0.2 0.17 11.9 0.0 3.1 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGE02200.1 - 0.00054 19.5 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 EGE02200.1 - 0.0006 19.6 0.1 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGE02200.1 - 0.00094 19.7 0.4 0.62 10.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGE02200.1 - 0.00099 19.1 0.0 0.054 13.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EGE02200.1 - 0.0012 19.3 0.7 1.7 9.1 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGE02200.1 - 0.0019 17.8 0.7 0.54 9.8 0.1 2.9 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 EGE02200.1 - 0.0027 17.0 0.0 0.2 10.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin SRP54 PF00448.22 EGE02200.1 - 0.0028 17.3 0.1 2.7 7.6 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGE02200.1 - 0.0061 16.7 0.2 4.4 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGE02200.1 - 0.011 15.9 0.5 4.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE02200.1 - 0.013 15.2 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGE02200.1 - 0.031 14.5 3.6 1.3 9.3 0.7 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 EGE02200.1 - 0.049 12.8 0.0 6.1 5.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 EGE02200.1 - 0.071 13.1 0.0 15 5.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain PRK PF00485.18 EGE02200.1 - 0.1 12.3 0.2 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 EGE02200.1 - 0.11 12.6 0.1 29 4.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGE02200.1 - 0.13 11.4 0.6 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 EGE02200.1 - 0.13 12.6 0.4 8.5 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_17 PF13207.6 EGE02200.1 - 2.6 8.5 4.9 15 6.0 0.0 3.4 4 1 0 4 4 2 0 AAA domain X PF00739.19 EGE02201.1 - 0.00047 20.3 0.8 0.087 13.0 0.1 2.2 2 0 0 2 2 2 2 Trans-activation protein X CBFNT PF08143.11 EGE02201.1 - 5 8.6 9.1 0.74 11.3 3.5 2.0 2 0 0 2 2 2 0 CBFNT (NUC161) domain CAP59_mtransfer PF11735.8 EGE02202.1 - 1.1e-66 224.9 0.2 2.6e-54 184.4 0.1 2.1 1 1 1 2 2 2 2 Cryptococcal mannosyltransferase 1 Stk19 PF10494.9 EGE02203.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 GST_N PF02798.20 EGE02209.1 - 1e-15 57.8 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE02209.1 - 1.8e-14 53.9 0.0 3.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE02209.1 - 5.5e-11 42.6 0.1 1.5e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGE02209.1 - 7.2e-11 42.2 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE02209.1 - 2.1e-10 40.6 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE02209.1 - 3.4e-06 27.0 0.0 8.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE02209.1 - 0.12 13.1 0.0 0.43 11.3 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain APH PF01636.23 EGE02210.1 - 2.2e-06 27.8 0.0 8.5e-05 22.6 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE02210.1 - 0.0067 15.8 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.6 EGE02211.1 - 0.025 14.6 0.0 0.074 13.1 0.0 1.8 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Iwr1 PF08574.10 EGE02212.1 - 7.5e-19 68.5 4.8 7.5e-19 68.5 4.8 3.0 3 1 1 4 4 4 1 Transcription factor Iwr1 RRM_1 PF00076.22 EGE02213.1 - 1.7e-40 136.7 0.0 5.3e-12 45.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE02213.1 - 1e-14 54.1 0.0 0.0053 16.6 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 EGE02213.1 - 2.1e-05 24.1 5.0 2.1e-05 24.1 5.0 2.8 2 1 0 2 2 2 1 Putative RRM domain DUF4523 PF15023.6 EGE02213.1 - 3.3e-05 23.8 0.0 0.59 9.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EGE02213.1 - 0.00013 22.0 0.0 0.26 11.4 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 EGE02213.1 - 0.00037 20.5 0.0 0.57 10.3 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif RRM_Rrp7 PF17799.1 EGE02213.1 - 0.038 13.8 0.0 1.3 8.8 0.0 2.9 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain YL1 PF05764.13 EGE02215.1 - 9.5e-64 215.8 31.5 9.5e-64 215.8 31.5 2.4 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EGE02215.1 - 9.8e-14 50.8 0.4 1.6e-13 50.1 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Ecl1 PF12855.7 EGE02216.1 - 2.9e-17 64.4 11.9 3.7e-17 64.0 11.9 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EGE02216.1 - 0.53 10.4 7.2 0.9 9.7 7.2 1.3 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.9 EGE02216.1 - 1.1 9.4 7.3 0.35 11.0 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_PR_Knuckle PF18445.1 EGE02216.1 - 3.5 7.5 6.4 15 5.5 2.0 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif tRNA-synt_2 PF00152.20 EGE02217.1 - 1.2e-90 303.8 0.0 1.6e-90 303.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE02217.1 - 7.3e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PUF PF00806.19 EGE02219.1 - 7.6e-29 97.8 0.0 1.4e-05 24.5 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EGE02219.1 - 6.2e-11 42.0 0.0 1.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.14 EGE02220.1 - 4.5e-25 88.5 0.1 6.5e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 MT-A70 Spore_YunB PF09560.10 EGE02220.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein YunB (Spo_YunB) Peptidase_C12 PF01088.21 EGE02221.1 - 3.5e-55 187.0 0.0 3.9e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Acyl_transf_1 PF00698.21 EGE02222.1 - 7.2e-75 252.4 0.4 1.2e-74 251.7 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EGE02222.1 - 2.1e-65 220.8 0.0 2.1e-65 220.8 0.0 2.7 3 0 0 3 3 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGE02222.1 - 2.6e-57 193.6 0.1 7e-57 192.2 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGE02222.1 - 1.9e-49 168.5 0.7 3.7e-49 167.6 0.7 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGE02222.1 - 1.4e-34 118.6 0.1 6.3e-34 116.5 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EGE02222.1 - 2.9e-21 76.6 0.0 6.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N PF00107.26 EGE02222.1 - 1.4e-20 73.6 0.9 1.6e-19 70.2 0.6 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGE02222.1 - 1.4e-16 60.5 0.6 7.3e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EGE02222.1 - 1.7e-13 51.0 0.0 1.8e-11 44.4 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGE02222.1 - 3.7e-13 50.7 0.0 2.4e-12 48.1 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.7 EGE02222.1 - 5.5e-06 27.1 1.1 2.4e-05 25.1 0.4 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_N PF08240.12 EGE02222.1 - 5.6e-06 26.2 0.3 1.6e-05 24.8 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGE02222.1 - 1.5e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGE02222.1 - 3.9e-05 23.2 0.4 0.0001 21.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EGE02222.1 - 0.00017 21.1 0.5 0.00047 19.6 0.5 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 EGE02222.1 - 0.00093 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EGE02222.1 - 0.0048 16.3 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase SAT PF16073.5 EGE02222.1 - 0.0096 15.7 1.1 0.89 9.2 0.6 2.8 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis AlaDh_PNT_C PF01262.21 EGE02222.1 - 0.01 15.1 2.2 0.02 14.2 2.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGE02222.1 - 0.15 12.7 0.7 0.87 10.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE02222.1 - 1.8 7.7 5.1 0.14 11.4 0.1 1.6 2 0 0 2 2 1 0 FAD binding domain DcpS PF05652.12 EGE02223.1 - 6.2e-34 117.0 0.0 1.1e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EGE02223.1 - 2e-31 108.8 0.4 3e-31 108.3 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alk_phosphatase PF00245.20 EGE02224.1 - 7.7e-71 239.2 3.3 4.9e-70 236.6 3.3 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EGE02224.1 - 7.8e-08 32.1 2.7 6.4e-07 29.1 2.3 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGE02224.1 - 1.6e-05 24.7 1.0 2.6e-05 24.0 1.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGE02224.1 - 0.00078 18.2 0.2 0.0016 17.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) GPAT_N PF14829.6 EGE02224.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Metalloenzyme PF01676.18 EGE02224.1 - 0.075 12.4 0.7 0.17 11.2 0.2 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily RNase_H2_suC PF08615.11 EGE02225.1 - 3.9e-27 95.2 0.2 6.1e-27 94.5 0.0 1.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Peptidase_S24 PF00717.23 EGE02225.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase S24-like RNase_T PF00929.24 EGE02226.1 - 4.9e-20 72.7 0.0 1.6e-19 71.0 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Nop53 PF07767.11 EGE02227.1 - 7.1e-101 338.5 39.7 1.1e-100 337.9 39.7 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) GTA_holin_3TM PF11351.8 EGE02227.1 - 1.8 9.1 6.6 1.1 9.8 3.1 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Myb_Cef PF11831.8 EGE02228.1 - 4.9e-51 173.6 5.7 4.9e-51 173.6 5.7 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGE02228.1 - 1.1e-21 76.7 5.8 2.1e-10 40.6 0.7 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE02228.1 - 1.5e-19 70.0 4.7 1.5e-12 47.6 1.4 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGE02228.1 - 0.059 13.5 0.1 1 9.5 0.0 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.18 EGE02229.1 - 2.6e-78 261.8 0.0 4.3e-78 261.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 EGE02229.1 - 9.8e-23 79.8 0.0 1.9e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 EGE02229.1 - 3.1e-22 77.9 0.3 5.9e-22 77.0 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EGE02229.1 - 0.0046 17.4 0.0 0.0089 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE02229.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1918 PF08940.11 EGE02229.1 - 0.082 12.5 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Orthopox_C10L PF07020.11 EGE02230.1 - 0.61 10.9 7.5 10 6.9 0.1 3.5 3 0 0 3 3 3 0 Orthopoxvirus C10L protein TMEM171 PF15471.6 EGE02230.1 - 5.8 5.8 6.9 20 4.1 6.9 1.9 1 0 0 1 1 1 0 Transmembrane protein family 171 F1F0-ATPsyn_F PF10791.9 EGE02231.1 - 1.3e-38 131.4 0.1 1.4e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EGE02231.1 - 0.0079 16.5 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 EGE02232.1 - 2.2e-36 124.0 2.0 3.2e-36 123.5 2.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Nipped-B_C PF12830.7 EGE02233.1 - 6.2e-48 163.3 6.7 4.7e-46 157.1 1.1 3.8 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGE02233.1 - 1.2e-10 41.4 2.5 1.2e-10 41.4 2.5 3.0 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EGE02233.1 - 0.00032 20.8 5.2 0.16 12.0 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EGE02233.1 - 0.00037 19.8 0.8 0.64 9.2 0.0 2.9 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EGE02233.1 - 0.0011 19.0 3.5 0.82 10.1 0.3 5.0 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.20 EGE02233.1 - 0.036 12.6 9.4 0.28 9.7 7.2 3.3 2 1 1 3 3 3 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGE02233.1 - 0.11 13.1 0.7 1.8 9.2 0.2 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Methyltransf_11 PF08241.12 EGE02234.1 - 2e-08 34.7 0.0 3.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02234.1 - 3.5e-06 27.6 0.0 9.8e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE02234.1 - 0.00015 21.2 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGE02234.1 - 0.18 11.6 0.0 0.8 9.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain TFIIS_C PF01096.18 EGE02235.1 - 4.7e-15 55.1 2.1 4.7e-15 55.1 2.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGE02235.1 - 2.5e-06 27.3 0.5 2.5e-06 27.3 0.5 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit RecR PF02132.15 EGE02235.1 - 0.0024 17.4 0.9 0.0024 17.4 0.9 2.0 2 0 0 2 2 2 1 RecR protein Ribosomal_S27e PF01667.17 EGE02235.1 - 0.012 15.2 3.9 2.6 7.8 0.0 3.3 2 1 1 3 3 3 0 Ribosomal protein S27 zinc_ribbon_2 PF13240.6 EGE02235.1 - 0.015 15.0 8.7 7.4 6.4 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGE02235.1 - 0.018 14.4 8.4 4.5 6.8 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EGE02235.1 - 0.031 14.2 3.4 4.9 7.2 0.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DZR PF12773.7 EGE02235.1 - 0.032 14.3 7.3 0.11 12.5 0.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon UCH_1 PF13423.6 EGE02235.1 - 0.033 13.8 0.5 0.04 13.5 0.5 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_1f PF01921.18 EGE02235.1 - 0.038 12.9 0.2 0.063 12.2 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) NMD3 PF04981.13 EGE02235.1 - 0.041 13.4 3.8 0.13 11.7 0.2 2.1 1 1 1 2 2 2 0 NMD3 family zf-RING_7 PF02591.15 EGE02235.1 - 0.1 12.8 8.7 1.1 9.5 0.1 3.5 3 1 1 4 4 4 0 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 EGE02235.1 - 0.11 12.7 3.0 1.8 8.9 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbon DpnI PF06044.12 EGE02235.1 - 0.19 11.4 2.2 0.29 10.7 0.1 2.0 1 1 0 2 2 2 0 Dam-replacing family zf-C4_Topoisom PF01396.19 EGE02235.1 - 0.4 10.5 4.3 1 9.2 0.2 3.1 2 2 1 3 3 3 0 Topoisomerase DNA binding C4 zinc finger CpXC PF14353.6 EGE02235.1 - 0.61 10.1 5.2 2.9 8.0 2.6 2.5 1 1 0 1 1 1 0 CpXC protein Zn-ribbon_8 PF09723.10 EGE02235.1 - 0.85 9.8 0.1 0.85 9.8 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Nudix_N_2 PF14803.6 EGE02235.1 - 1.2 9.1 9.9 0.64 10.0 0.4 2.8 3 0 0 3 3 3 0 Nudix N-terminal Zn_ribbon_recom PF13408.6 EGE02235.1 - 1.3 9.5 8.1 3.5 8.2 0.4 2.6 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Auto_anti-p27 PF06677.12 EGE02235.1 - 1.4 9.2 6.1 4.9 7.4 0.1 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2 PF00096.26 EGE02235.1 - 1.6 9.3 5.1 13 6.4 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrfB_Zn_ribbon PF07282.11 EGE02235.1 - 4.3 7.3 8.8 10 6.2 0.4 2.7 2 2 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EGE02235.1 - 4.5 6.9 13.5 5.7 6.5 0.4 3.3 2 2 0 3 3 3 0 TFIIB zinc-binding zf-IS66 PF13005.7 EGE02235.1 - 7.9 7.0 12.1 3.8 8.0 0.1 3.6 3 1 1 4 4 3 0 zinc-finger binding domain of transposase IS66 HEAT_2 PF13646.6 EGE02236.1 - 2.5e-27 95.1 7.1 1.7e-11 44.4 0.1 3.6 2 2 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EGE02236.1 - 4.3e-19 67.2 1.6 0.0032 18.0 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGE02236.1 - 2.8e-05 24.0 2.8 9.7 6.8 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGE02236.1 - 0.00027 21.4 4.4 0.24 11.9 0.0 5.0 3 2 2 5 5 5 1 HEAT-like repeat Pyr_redox_2 PF07992.14 EGE02237.1 - 8.4e-41 140.1 0.0 1.2e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE02237.1 - 2.4e-10 40.8 0.0 4.8e-09 36.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGE02237.1 - 1.2e-05 24.5 0.1 4.6e-05 22.7 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGE02237.1 - 0.00018 21.1 0.3 0.0006 19.5 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EGE02237.1 - 0.0003 20.2 0.1 0.00074 18.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGE02237.1 - 0.003 18.0 0.1 0.009 16.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 EGE02237.1 - 0.24 11.4 0.9 3.3 7.7 0.0 2.9 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand CLTH PF10607.9 EGE02238.1 - 3.4e-33 114.6 0.3 4.7e-33 114.2 0.3 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGE02238.1 - 3.1e-09 36.5 0.1 6.9e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 LisH PRK PF00485.18 EGE02239.1 - 1e-55 188.5 0.0 1.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGE02239.1 - 3.9e-06 27.5 0.0 8.1e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGE02239.1 - 0.00019 20.8 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 EGE02239.1 - 0.0047 17.0 0.1 0.012 15.7 0.1 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain CPT PF07931.12 EGE02239.1 - 0.0078 16.1 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EGE02239.1 - 0.014 15.1 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 EGE02239.1 - 0.025 15.0 0.0 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EGE02239.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EGE02239.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGE02239.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NUC153 PF08159.12 EGE02240.1 - 2.6e-14 52.7 8.3 1.4e-13 50.4 0.2 3.6 3 0 0 3 3 3 2 NUC153 domain ATP-synt_J PF04911.12 EGE02240.1 - 0.055 13.1 0.5 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase j chain DUF4148 PF13663.6 EGE02240.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Npa1 PF11707.8 EGE02241.1 - 4.4e-93 312.3 1.1 4.4e-93 312.3 1.1 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGE02241.1 - 6.9e-57 192.3 0.1 6e-56 189.2 0.0 2.6 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Mating_N PF12731.7 EGE02241.1 - 0.018 15.1 0.8 0.069 13.3 0.1 2.4 2 0 0 2 2 2 0 Mating-type protein beta 1 HA2 PF04408.23 EGE02243.1 - 1.1e-23 83.5 0.7 4.3e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGE02243.1 - 2.7e-18 66.1 0.0 5.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGE02243.1 - 2.2e-13 50.5 0.0 5.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EGE02243.1 - 0.00014 22.2 0.1 0.0004 20.7 0.1 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EGE02243.1 - 0.00029 20.6 0.2 0.00078 19.3 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGE02243.1 - 0.0014 17.8 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGE02243.1 - 0.025 14.9 0.1 0.077 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGE02243.1 - 0.075 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGE02243.1 - 0.097 12.8 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SUV3_C PF12513.8 EGE02244.1 - 2.4e-16 59.4 0.1 4.7e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EGE02244.1 - 3.3e-10 40.3 0.0 7.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EGE02244.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 EGE02244.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Sec1 PF00995.23 EGE02245.1 - 1.7e-112 377.6 0.0 2.2e-112 377.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 EGE02246.1 - 1.4e-07 31.3 0.2 3.2e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 EGE02247.1 - 1.4e-13 50.8 0.0 1.6e-10 40.7 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 EGE02247.1 - 8.1e-06 25.9 0.0 2.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGE02247.1 - 8.5e-06 25.5 0.0 3.5e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGE02247.1 - 0.00019 21.0 0.0 0.00049 19.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE02248.1 - 2.9e-48 165.0 0.0 6.7e-48 163.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGE02248.1 - 1.8e-47 161.9 0.0 2.3e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGE02248.1 - 4.2e-15 55.5 0.0 6.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGE02248.1 - 1.9e-12 47.0 0.0 2.4e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGE02248.1 - 1.6e-11 43.9 0.0 2.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EGE02248.1 - 5.3e-11 42.3 0.0 9.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE02248.1 - 2.6e-07 30.7 0.0 4.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGE02248.1 - 1.6e-05 24.6 0.0 4.8e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EGE02248.1 - 0.00012 21.4 0.0 0.014 14.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGE02248.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding UDPG_MGDP_dh_N PF03721.14 EGE02248.1 - 0.012 15.3 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EGE02248.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3HCDH_N PF02737.18 EGE02248.1 - 0.029 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGE02249.1 - 8.2e-26 91.0 0.0 9.5e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE02249.1 - 1.2e-09 38.1 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGE02249.1 - 8.4e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGE02249.1 - 3.9e-05 22.8 0.0 5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGE02249.1 - 0.00047 20.4 0.0 0.00081 19.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FIST_C PF10442.9 EGE02249.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 FIST C domain PAT1 PF09770.9 EGE02250.1 - 0 1140.0 7.5 0 1139.8 7.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.16 EGE02251.1 - 1.1e-127 425.8 10.4 1.4e-127 425.5 10.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SIC PF03482.13 EGE02251.1 - 0.026 14.7 1.2 0.068 13.4 1.2 1.7 1 0 0 1 1 1 0 sic protein repeat Ribosom_S12_S23 PF00164.25 EGE02252.1 - 2e-30 104.7 1.8 2.8e-30 104.3 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 HTH_Tnp_IS1 PF12759.7 EGE02252.1 - 0.031 13.9 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 InsA C-terminal domain UMP1 PF05348.11 EGE02253.1 - 7e-39 132.7 0.1 8.9e-39 132.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 EGE02254.1 - 1.7e-12 47.4 0.0 4.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGE02254.1 - 0.006 17.1 0.1 0.017 15.7 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EGE02254.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family IML1 PF12257.8 EGE02255.1 - 5.9e-108 360.3 0.0 8.5e-108 359.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGE02255.1 - 3.7e-29 100.6 1.0 7.6e-29 99.6 1.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC48_2 PF02933.17 EGE02255.1 - 0.14 11.9 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 FNIP_N PF14636.6 EGE02256.1 - 5.9e-32 111.8 0.2 5.9e-32 111.8 0.2 4.9 2 2 1 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 EGE02256.1 - 0.048 13.7 0.2 0.14 12.1 0.1 1.8 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain C9orf72-like PF15019.6 EGE02256.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 C9orf72-like protein family SNF2_N PF00176.23 EGE02257.1 - 3.7e-51 173.9 0.0 7.3e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE02257.1 - 6.3e-10 39.4 0.0 1.8e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE02257.1 - 3.6e-05 23.8 0.0 3.6e-05 23.8 0.0 2.4 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit Trypan_PARP PF05887.11 EGE02257.1 - 0.00017 21.6 13.2 0.00017 21.6 13.2 2.2 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 EGE02257.1 - 9.8 6.7 23.4 5.6 7.5 12.9 2.5 2 0 0 2 2 2 0 TonB polyproline region TPR_2 PF07719.17 EGE02258.1 - 2.4e-10 39.7 19.6 0.0003 20.7 0.0 6.4 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGE02258.1 - 7e-08 32.0 9.0 0.00031 20.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02258.1 - 1.1e-07 31.5 0.4 0.22 11.8 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02258.1 - 4.8e-06 27.0 20.0 0.044 14.3 4.2 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02258.1 - 8.3e-05 23.2 22.2 0.00035 21.2 0.2 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE02258.1 - 0.00039 20.7 15.0 1.2 9.4 3.3 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE02258.1 - 0.001 19.7 21.4 0.034 14.9 0.3 7.8 8 2 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE02258.1 - 0.0014 18.5 7.0 0.71 10.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE02258.1 - 0.0059 17.2 14.8 6.3 7.7 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE02258.1 - 0.0085 15.8 12.5 0.01 15.5 0.1 5.2 6 0 0 6 6 6 1 TPR repeat TPR_17 PF13431.6 EGE02258.1 - 0.26 11.8 5.1 28 5.4 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGE02258.1 - 0.3 11.3 14.7 0.83 9.8 0.1 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGE02258.1 - 3.5 7.6 11.4 29 4.7 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Pmp3 PF01679.17 EGE02259.1 - 5e-19 68.2 9.5 6.7e-19 67.8 9.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SUIM_assoc PF16619.5 EGE02259.1 - 0.009 16.1 2.9 0.016 15.3 2.9 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF908 PF06012.12 EGE02259.1 - 0.78 9.1 3.7 0.9 8.9 3.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SH3_9 PF14604.6 EGE02260.1 - 1.6e-05 24.7 1.7 1.7e-05 24.6 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGE02260.1 - 0.00023 20.7 0.1 0.00042 19.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Rax2 PF12768.7 EGE02260.1 - 0.021 14.3 0.0 0.047 13.1 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Syndecan PF01034.20 EGE02260.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 EGE02260.1 - 0.36 10.3 1.8 0.69 9.4 1.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 EGE02264.1 - 2.1e-18 66.3 0.1 2.1e-18 66.3 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02264.1 - 0.00019 21.5 8.8 0.00042 20.4 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WBS_methylT PF12589.8 EGE02264.1 - 0.18 12.5 2.8 0.63 10.8 2.8 1.9 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Na_Ca_ex PF01699.24 EGE02265.1 - 1.4e-41 142.0 43.7 3e-23 82.5 15.2 2.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein GHMP_kinases_N PF00288.26 EGE02266.1 - 1.6e-15 57.1 1.8 3.8e-15 55.9 1.8 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGE02266.1 - 1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal MCM PF00493.23 EGE02267.1 - 2.4e-99 331.0 0.1 3.6e-99 330.4 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGE02267.1 - 7.2e-38 129.3 0.2 1.5e-37 128.3 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EGE02267.1 - 1e-32 112.5 2.0 2.6e-32 111.3 2.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EGE02267.1 - 6e-24 84.3 0.5 1.7e-23 82.8 0.5 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGE02267.1 - 1e-20 74.3 1.4 2.7e-20 72.9 0.4 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE02267.1 - 7.2e-05 22.3 0.0 0.00037 19.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE02267.1 - 0.0038 17.2 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGE02267.1 - 0.0059 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGE02267.1 - 0.018 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GIDA_assoc PF13932.6 EGE02267.1 - 0.03 14.5 1.8 0.078 13.2 1.8 1.7 1 0 0 1 1 1 0 GidA associated domain EamA PF00892.20 EGE02268.1 - 1.2e-05 25.5 14.4 9e-05 22.7 14.4 1.9 1 1 0 1 1 1 1 EamA-like transporter family Trp_oprn_chp PF09534.10 EGE02268.1 - 0.04 13.7 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM234 PF10639.9 EGE02268.1 - 0.053 13.6 4.2 0.077 13.0 4.2 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 EGE02269.1 - 1e-88 298.0 26.2 1e-88 298.0 26.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGE02269.1 - 1.1e-08 35.4 0.0 0.00084 19.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain ATPase_gene1 PF09527.10 EGE02269.1 - 0.083 13.1 7.5 4.1 7.6 1.2 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CBFD_NFYB_HMF PF00808.23 EGE02270.1 - 7.5e-14 51.8 0.7 1.3e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UCR_TM PF02921.14 EGE02271.1 - 7.1e-11 42.4 0.5 1.6e-10 41.3 0.5 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EGE02271.1 - 2e-10 40.5 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.11 EGE02272.1 - 6.6e-88 293.7 9.4 9e-88 293.3 9.4 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family MBD_C PF14048.6 EGE02272.1 - 0.0072 17.0 0.3 0.031 15.0 0.1 2.3 2 0 0 2 2 2 1 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF737 PF05300.11 EGE02272.1 - 0.012 16.0 7.8 0.059 13.7 7.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF737) PsbH PF00737.20 EGE02272.1 - 0.045 13.5 0.8 0.094 12.5 0.8 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein SKA1 PF07160.12 EGE02272.1 - 0.88 9.4 9.6 0.043 13.7 2.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Aminotran_1_2 PF00155.21 EGE02273.1 - 1.3e-32 113.4 0.0 1.3e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Zn_clus PF00172.18 EGE02274.1 - 2.2e-16 59.7 30.3 3.7e-08 33.4 10.3 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE02274.1 - 9.6e-10 37.9 1.4 9.6e-10 37.9 1.4 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain PNP_phzG_C PF10590.9 EGE02275.1 - 7.7e-21 73.9 4.4 8.3e-21 73.8 1.7 2.3 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EGE02275.1 - 6.3e-11 42.3 0.0 4.9e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EGE02275.1 - 0.012 16.2 0.1 0.11 13.1 0.1 2.3 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PPR_2 PF13041.6 EGE02276.1 - 7.2e-41 138.2 13.9 1e-08 35.2 0.0 13.1 11 3 3 14 14 14 6 PPR repeat family PPR_3 PF13812.6 EGE02276.1 - 4.1e-31 106.8 0.5 0.00013 21.9 0.0 10.2 8 4 3 11 11 11 6 Pentatricopeptide repeat domain PPR PF01535.20 EGE02276.1 - 2.9e-23 80.4 15.1 0.0011 19.1 0.0 13.3 14 0 0 14 14 14 4 PPR repeat PPR_1 PF12854.7 EGE02276.1 - 3.3e-17 61.9 0.2 9.3e-06 25.2 0.1 9.2 10 0 0 10 10 10 2 PPR repeat PPR_long PF17177.4 EGE02276.1 - 1.1e-16 60.9 11.4 7.8e-07 28.7 0.3 5.9 3 1 4 7 7 7 5 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EGE02276.1 - 6.3e-08 33.0 0.0 8.8e-06 26.1 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 EGE02276.1 - 0.0076 15.4 0.6 2.2 7.4 0.0 3.7 4 0 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway F-box PF00646.33 EGE02277.1 - 2.1e-05 24.3 0.2 5.2e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGE02277.1 - 0.00022 21.0 1.2 0.00063 19.6 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGE02277.1 - 0.0014 18.5 1.4 0.0017 18.2 0.1 1.8 2 0 0 2 2 2 1 F-box Peptidase_S41 PF03572.18 EGE02278.1 - 2.3e-10 40.3 0.0 3.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 Ribosomal_L7Ae PF01248.26 EGE02279.1 - 4.8e-17 61.5 0.1 1.1e-16 60.3 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EGE02279.1 - 0.0048 17.0 0.4 0.014 15.4 0.4 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 RSN1_7TM PF02714.15 EGE02280.1 - 5.4e-93 311.3 22.8 2.8e-92 308.9 15.6 2.9 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGE02280.1 - 2.7e-43 147.4 3.3 3.5e-43 147.0 1.2 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGE02280.1 - 7.5e-37 127.3 0.0 1.5e-36 126.3 0.0 1.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGE02280.1 - 9e-29 99.5 0.0 1.9e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter EHN PF06441.12 EGE02283.1 - 5.7e-36 123.2 2.9 6e-35 119.9 0.2 2.5 3 0 0 3 3 3 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EGE02283.1 - 1.8e-16 60.5 0.3 5.1e-16 59.1 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE02283.1 - 4.7e-07 30.6 2.3 8.8e-07 29.7 2.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family REJ PF02010.15 EGE02284.1 - 0.0074 15.1 0.1 0.0096 14.7 0.1 1.1 1 0 0 1 1 1 1 REJ domain RSN1_TM PF13967.6 EGE02285.1 - 0.025 14.3 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport tRNA_NucTran2_2 PF13735.6 EGE02286.1 - 0.045 13.7 0.4 0.074 13.0 0.4 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Ribosomal_L17 PF01196.19 EGE02286.1 - 0.19 12.6 1.7 0.58 11.1 0.0 2.5 3 1 0 3 3 3 0 Ribosomal protein L17 DUF2849 PF11011.8 EGE02286.1 - 0.31 11.7 3.0 0.63 10.7 2.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2849) DUF4665 PF15679.5 EGE02288.1 - 0.27 11.9 0.2 0.27 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Pyridox_oxase_2 PF12766.7 EGE02289.1 - 1e-22 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase LRR_9 PF14580.6 EGE02290.1 - 6.6e-58 195.1 0.1 9.8e-58 194.5 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGE02290.1 - 4.8e-10 39.0 14.9 5.7e-06 26.0 3.9 3.1 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EGE02290.1 - 1.5e-05 25.2 11.9 0.00011 22.5 1.4 3.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) T4_Gp59_C PF08994.10 EGE02290.1 - 0.017 15.7 0.0 0.029 15.0 0.0 1.4 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term HTH_38 PF13936.6 EGE02290.1 - 0.049 13.4 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0128 PF03673.13 EGE02290.1 - 0.091 12.2 0.2 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) DUF4349 PF14257.6 EGE02290.1 - 0.14 11.6 1.3 0.23 10.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) GDA1_CD39 PF01150.17 EGE02291.1 - 6e-110 367.8 0.0 8.1e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.21 EGE02292.1 - 1.1e-17 63.9 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 EGE02293.1 - 2.6e-80 269.5 0.0 3e-75 252.9 0.0 2.0 1 1 1 2 2 2 2 Pantoate-beta-alanine ligase DEAD PF00270.29 EGE02294.1 - 1.6e-40 138.8 0.0 2.7e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE02294.1 - 9.7e-21 74.2 0.0 5.6e-20 71.7 0.0 2.2 1 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGE02294.1 - 2e-18 66.3 0.0 4.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGE02294.1 - 4.1e-07 30.2 0.1 3.6e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGE02294.1 - 0.013 14.8 0.4 0.022 14.0 0.0 1.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase PI3K_1B_p101 PF10486.9 EGE02294.1 - 1.5 6.5 9.1 0.15 9.9 4.3 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit WD40 PF00400.32 EGE02295.1 - 2.7e-11 43.8 10.4 0.00011 22.9 0.3 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE02295.1 - 0.00025 21.3 0.2 1.3 9.4 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ParD_like PF11903.8 EGE02295.1 - 0.033 14.3 0.3 0.084 13.0 0.3 1.6 1 0 0 1 1 1 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system Fungal_trans_2 PF11951.8 EGE02296.1 - 1.4e-09 37.2 4.7 4.9e-08 32.2 0.4 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02296.1 - 9e-06 25.7 10.1 2.3e-05 24.4 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGE02297.1 - 4.2e-44 150.9 55.2 2e-43 148.7 53.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE02297.1 - 3.8e-10 39.2 35.4 1.2e-07 31.0 19.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EGE02297.1 - 1.4e-05 23.7 23.0 2.2e-05 23.1 23.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CbtA PF09490.10 EGE02297.1 - 0.00092 19.1 4.9 0.0032 17.3 3.6 2.7 1 1 1 2 2 2 1 Probable cobalt transporter subunit (CbtA) GATase PF00117.28 EGE02298.1 - 3.6e-14 53.0 0.0 4.8e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGE02298.1 - 0.034 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EGE02298.1 - 0.044 13.5 0.5 0.28 10.9 0.5 2.3 1 1 0 1 1 1 0 Peptidase C26 DUF775 PF05603.12 EGE02299.1 - 2.3e-65 219.9 0.0 2.6e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 EGE02300.1 - 6.7e-12 45.6 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EGE02300.1 - 5.4e-10 39.3 0.0 7.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RNA_pol_Rpb8 PF03870.15 EGE02301.1 - 9.7e-47 158.7 0.0 1.1e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 EGE02302.1 - 3e-119 398.5 0.0 3.5e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EGE02304.1 - 4.8e-15 55.4 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain NMU PF02070.15 EGE02304.1 - 0.085 12.8 0.4 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Neuromedin U UPF0086 PF01868.16 EGE02305.1 - 9.3e-32 108.8 0.1 1.6e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 PGBA_C PF15437.6 EGE02305.1 - 0.51 10.7 4.2 17 5.9 0.7 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Copper-bind PF00127.20 EGE02306.1 - 0.013 16.0 0.1 0.035 14.5 0.1 1.7 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Apt1 PF10351.9 EGE02306.1 - 5.8 5.6 7.2 6.9 5.4 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_2 PF12796.7 EGE02308.1 - 4.5e-69 229.1 6.7 3e-13 50.1 0.0 6.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE02308.1 - 1.7e-38 130.1 9.8 2.2e-10 40.5 0.1 7.3 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE02308.1 - 2.3e-37 126.9 8.3 1.9e-08 34.7 0.0 9.0 4 4 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE02308.1 - 5.6e-29 97.0 2.0 0.00018 21.7 0.0 10.8 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 EGE02308.1 - 9.1e-28 95.5 0.7 0.049 14.1 0.0 10.6 10 1 0 10 10 10 8 Ankyrin repeat Trehalase_Ca-bi PF07492.11 EGE02308.1 - 0.00044 19.9 1.7 14 5.5 0.1 4.7 4 0 0 4 4 4 1 Neutral trehalase Ca2+ binding domain MFS_1 PF07690.16 EGE02309.1 - 8.1e-24 84.2 28.6 1.3e-23 83.5 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Phos_pyr_kin PF08543.12 EGE02309.1 - 0.23 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase zf-C3HC4 PF00097.25 EGE02310.1 - 0.022 14.6 38.3 0.31 10.9 7.8 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 EGE02310.1 - 0.073 13.3 23.3 1.2 9.3 3.9 3.3 3 0 0 3 3 3 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 EGE02310.1 - 0.2 11.5 38.5 0.37 10.7 6.5 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TetR_C_19 PF17924.1 EGE02311.1 - 0.0082 16.7 0.2 0.063 13.9 0.1 2.0 1 1 1 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Cofilin_ADF PF00241.20 EGE02312.1 - 5.2e-18 65.0 0.0 6.5e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 EGE02313.1 - 1.3e-35 122.2 0.0 2.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EGE02313.1 - 0.045 13.9 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Ras PF00071.22 EGE02314.1 - 7.5e-60 201.2 0.2 8.7e-60 201.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE02314.1 - 3.5e-20 72.4 0.0 5.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE02314.1 - 2.2e-07 30.5 0.0 2.5e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE02314.1 - 3.2e-05 23.6 0.1 0.00031 20.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE02314.1 - 4.9e-05 23.3 0.4 0.17 11.8 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGE02314.1 - 0.001 18.6 0.0 0.0016 17.9 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGE02314.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGE02314.1 - 0.0031 17.5 0.1 0.0059 16.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF2075 PF09848.9 EGE02314.1 - 0.18 11.0 0.4 11 5.1 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EGE02314.1 - 0.25 11.4 0.5 0.89 9.6 0.5 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EGE02314.1 - 0.32 10.7 1.2 3.4 7.3 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein adh_short PF00106.25 EGE02315.1 - 4.2e-53 179.7 0.0 5.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE02315.1 - 3.8e-37 128.1 0.0 4.4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE02315.1 - 8.4e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGE02315.1 - 0.0019 17.4 0.2 0.0061 15.7 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGE02315.1 - 0.0054 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Lin0512_fam PF09585.10 EGE02315.1 - 0.11 12.6 0.5 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Epimerase PF01370.21 EGE02315.1 - 0.12 11.8 0.2 0.23 10.9 0.1 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EGE02315.1 - 0.14 12.0 0.1 0.41 10.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GATA PF00320.27 EGE02317.1 - 2.1e-28 97.6 18.7 2.3e-15 55.9 4.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGE02317.1 - 1.7e-07 30.6 4.5 0.0029 17.1 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EGE02317.1 - 0.00012 22.1 1.8 0.078 13.1 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 EGE02317.1 - 0.003 17.7 6.4 0.27 11.4 0.9 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.18 EGE02317.1 - 0.024 14.7 7.5 1 9.5 0.1 2.7 3 0 0 3 3 2 0 Putative GTPase activating protein for Arf TDP43_N PF18694.1 EGE02317.1 - 0.2 11.6 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 EGE02317.1 - 0.24 11.5 15.5 0.86 9.7 1.0 3.5 2 2 1 3 3 3 0 Double zinc ribbon Eapp_C PF10238.9 EGE02317.1 - 1.1 9.3 9.1 20 5.3 5.7 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-RRN7 PF11781.8 EGE02317.1 - 1.2 8.9 8.0 2.3 8.0 0.3 3.0 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 EGE02317.1 - 1.6 8.6 4.2 23 4.9 0.7 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 EGE02317.1 - 2.6 8.0 14.1 0.85 9.6 0.3 3.2 3 0 0 3 3 3 0 Putative transposase DNA-binding domain COPI_assoc PF08507.10 EGE02318.1 - 4e-30 104.5 5.3 4.7e-30 104.3 5.3 1.0 1 0 0 1 1 1 1 COPI associated protein SPC12 PF06645.13 EGE02318.1 - 0.033 14.3 1.3 0.033 14.3 1.3 1.9 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DAO PF01266.24 EGE02319.1 - 2.8e-33 116.0 0.2 3.3e-33 115.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE02319.1 - 0.00071 19.8 0.1 0.0016 18.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE02319.1 - 0.0035 17.9 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE02319.1 - 0.022 14.0 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EGE02319.1 - 0.027 14.7 0.2 0.09 13.0 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EGE02319.1 - 0.046 13.0 0.1 0.046 13.0 0.1 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EGE02319.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding DUF1188 PF06690.11 EGE02319.1 - 0.12 11.9 0.1 9.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) GMC_oxred_N PF00732.19 EGE02319.1 - 0.12 11.7 0.2 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.16 EGE02319.1 - 0.14 11.7 0.3 0.45 10.1 0.2 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_transf_54 PF04666.13 EGE02320.1 - 0.014 14.3 0.0 0.73 8.6 0.0 2.1 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region OTU PF02338.19 EGE02321.1 - 4.7e-13 49.7 0.0 7.5e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 EGE02321.1 - 0.0027 17.4 0.8 0.013 15.2 0.0 2.3 3 0 0 3 3 3 1 CUE domain IL28A PF15177.6 EGE02322.1 - 0.084 12.7 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 Interleukin-28A MCU PF04678.13 EGE02322.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter zf-C2H2 PF00096.26 EGE02322.1 - 0.72 10.4 7.2 3.4 8.3 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 EGE02323.1 - 1.6e-66 224.6 0.0 6.1e-66 222.7 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF243 PF03103.17 EGE02323.1 - 0.011 16.0 1.8 0.069 13.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF3328 PF11807.8 EGE02324.1 - 5.9e-46 157.0 0.1 8.6e-46 156.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) R2K_2 PF18299.1 EGE02324.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Palm_thioest PF02089.15 EGE02327.1 - 1.2e-145 483.7 0.0 5e-75 252.5 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGE02327.1 - 5.6e-08 32.7 0.1 0.011 15.4 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 EGE02327.1 - 2.9e-07 30.1 0.0 0.021 14.1 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 EGE02327.1 - 0.00033 21.3 0.2 0.095 13.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family STALD PF18185.1 EGE02327.1 - 0.0029 17.0 0.0 0.36 10.1 0.0 2.2 2 0 0 2 2 2 1 Sir2- and TIR-associating SLOG family FSH1 PF03959.13 EGE02327.1 - 0.021 14.5 0.1 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) WYL_3 PF18488.1 EGE02327.1 - 0.037 14.4 0.1 18 5.8 0.0 2.6 2 0 0 2 2 2 0 WYL domain HCNGP PF07818.13 EGE02327.1 - 0.042 14.5 1.7 11 6.7 0.1 2.5 2 0 0 2 2 2 0 HCNGP-like protein DUF4188 PF13826.6 EGE02327.1 - 0.045 14.1 0.0 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) HTH_18 PF12833.7 EGE02327.1 - 0.059 13.7 0.0 27 5.1 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain DCAF15_WD40 PF14939.6 EGE02327.1 - 0.086 12.5 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 DDB1-and CUL4-substrate receptor 15, WD repeat Acetyltransf_1 PF00583.25 EGE02328.1 - 1.2e-07 32.0 0.0 1.6e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE02328.1 - 5.2e-07 30.0 0.0 8.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGE02328.1 - 9.1e-06 25.6 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE02328.1 - 0.0079 16.1 0.0 0.03 14.3 0.0 2.0 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EGE02328.1 - 0.05 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3638 PF12340.8 EGE02329.1 - 4.7e-91 304.1 0.1 8.3e-91 303.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EGE02329.1 - 1e-15 56.8 0.7 3.7e-14 51.8 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) CENP-L PF13092.6 EGE02330.1 - 2.3e-52 177.5 0.1 3e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Cue1_U7BR PF18499.1 EGE02330.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Sulfate_transp PF00916.20 EGE02331.1 - 2.7e-76 256.8 13.7 3.7e-76 256.4 13.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGE02331.1 - 1.7e-15 56.7 0.0 3e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGE02331.1 - 0.0048 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGE02331.1 - 6.1 7.3 17.0 0.081 13.3 5.4 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily EIF_2_alpha PF07541.12 EGE02332.1 - 2.5e-36 124.3 0.0 4.8e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGE02332.1 - 1.6e-13 50.8 0.9 3e-13 49.9 0.9 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RHH_1 PF01402.21 EGE02332.1 - 1.1 9.3 3.9 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PKD_channel PF08016.12 EGE02333.1 - 6.9e-08 31.6 20.4 3.9e-07 29.1 16.6 2.8 2 1 0 2 2 2 1 Polycystin cation channel DNA_alkylation PF08713.11 EGE02333.1 - 0.15 11.8 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme CAML PF14963.6 EGE02333.1 - 2.2 8.3 4.0 2 8.4 2.0 1.9 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand FYVE PF01363.21 EGE02334.1 - 3.4e-22 78.3 28.5 4.1e-17 62.1 5.3 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EGE02334.1 - 1.2e-17 63.3 0.6 3.2e-17 62.0 0.6 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain YqaH PF17448.2 EGE02334.1 - 0.014 15.7 0.2 0.036 14.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized YqaH-like zf-AN1 PF01428.16 EGE02334.1 - 0.016 15.4 5.8 0.016 15.4 5.8 4.0 4 1 1 5 5 5 0 AN1-like Zinc finger Fer4_21 PF14697.6 EGE02334.1 - 0.02 15.0 4.2 0.02 15.0 4.2 2.6 3 0 0 3 3 2 0 4Fe-4S dicluster domain TMF_TATA_bd PF12325.8 EGE02334.1 - 0.044 14.0 2.1 0.062 13.5 0.5 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 EGE02334.1 - 0.073 13.3 1.4 0.2 11.9 1.4 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain C6_DPF PF10170.9 EGE02334.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.6 3 0 0 3 3 2 0 Cysteine-rich domain Prok-RING_4 PF14447.6 EGE02334.1 - 0.34 10.8 0.1 0.34 10.8 0.1 5.0 5 1 1 6 6 6 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EGE02334.1 - 1.3 8.9 4.3 31 4.5 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 EGE02334.1 - 2.4 8.1 5.5 2.9 7.9 0.3 3.4 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger E1-E2_ATPase PF00122.20 EGE02335.1 - 3.9e-20 72.1 0.0 9.5e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGE02335.1 - 3.1e-13 50.5 1.5 1.8e-06 28.4 2.5 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE02335.1 - 0.0036 17.1 0.2 0.027 14.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE02335.1 - 0.016 15.3 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) S6PP PF05116.13 EGE02335.1 - 0.052 13.1 0.5 0.29 10.6 0.0 2.3 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase ATP1G1_PLM_MAT8 PF02038.16 EGE02336.1 - 1.1 8.7 3.1 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family AA_permease_2 PF13520.6 EGE02338.1 - 7.7e-63 212.8 50.7 9.2e-63 212.5 50.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE02338.1 - 3.8e-20 72.0 40.4 3.8e-20 72.0 40.4 1.3 1 1 0 1 1 1 1 Amino acid permease GLTP PF08718.11 EGE02339.1 - 1.4e-47 161.8 0.1 1.8e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) ABC_tran_CTD PF16326.5 EGE02339.1 - 9.9 6.5 8.5 0.55 10.5 1.4 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain PH_4 PF15404.6 EGE02340.1 - 5.8e-56 189.2 1.5 5.1e-55 186.1 0.4 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 EGE02340.1 - 5.3e-22 77.2 0.1 1.3e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 EGE02340.1 - 2.9e-10 40.6 0.1 0.0087 16.6 0.0 5.4 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 EGE02340.1 - 0.002 18.4 0.1 0.14 12.5 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGE02340.1 - 0.029 14.7 0.0 0.7 10.3 0.0 3.2 4 0 0 4 4 4 0 Pleckstrin homology domain PH_13 PF16652.5 EGE02340.1 - 0.057 13.2 0.4 8 6.3 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain mRNA_stabil PF13929.6 EGE02340.1 - 0.11 11.5 0.2 0.23 10.4 0.2 1.4 1 0 0 1 1 1 0 mRNA stabilisation NAD_binding_10 PF13460.6 EGE02341.1 - 2.7e-08 33.9 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE02341.1 - 5e-06 26.2 0.0 1.5e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGE02341.1 - 0.0097 15.4 0.0 0.31 10.5 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EGE02341.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 EGE02341.1 - 0.13 12.9 0.0 0.67 10.6 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TFIIS_C PF01096.18 EGE02342.1 - 9.8e-19 66.9 2.3 9.8e-19 66.9 2.3 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGE02342.1 - 8.6e-06 25.5 9.9 0.0002 21.1 5.3 3.4 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EGE02342.1 - 0.0065 16.4 6.7 0.12 12.3 1.3 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_4 PF07975.12 EGE02342.1 - 0.098 12.9 4.9 1.4 9.2 0.3 2.6 2 2 0 2 2 2 0 TFIIH C1-like domain zf-Mss51 PF13824.6 EGE02342.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.0 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.6 EGE02342.1 - 2.7 8.6 12.4 3.9 8.1 0.3 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 EGE02342.1 - 3.1 7.8 10.8 15 5.6 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin PF00301.20 EGE02342.1 - 4.3 7.4 8.1 8.6 6.5 0.2 3.4 3 0 0 3 3 3 0 Rubredoxin GTP_EFTU PF00009.27 EGE02343.1 - 1.4e-54 184.6 0.0 2.1e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGE02343.1 - 4.2e-42 143.0 0.0 1e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGE02343.1 - 9.6e-15 54.7 1.4 3.1e-14 53.1 1.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGE02343.1 - 0.0013 18.8 0.2 0.014 15.5 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGE02343.1 - 0.009 15.9 1.2 0.027 14.4 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Chalcone_2 PF16035.5 EGE02344.1 - 1.4e-73 247.0 0.0 2.2e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGE02344.1 - 0.0075 16.4 0.1 0.026 14.6 0.0 1.9 2 0 0 2 2 2 1 Chalcone isomerase-like Glutaredoxin PF00462.24 EGE02345.1 - 5.3e-20 71.4 0.0 7.8e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EGE02345.1 - 0.029 14.8 0.0 0.043 14.2 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EGE02345.1 - 0.037 14.4 0.1 0.052 14.0 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Adeno_E3_CR2 PF02439.15 EGE02348.1 - 2.2 8.1 4.4 4.2 7.2 4.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Macoilin PF09726.9 EGE02348.1 - 2.8 6.4 12.9 3.7 6.0 12.9 1.2 1 0 0 1 1 1 0 Macoilin family CH PF00307.31 EGE02349.1 - 9.5e-07 29.0 0.4 2.3e-06 27.8 0.6 1.5 1 1 1 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 EGE02349.1 - 0.054 13.6 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 CH-like domain in sperm protein ADH_zinc_N_2 PF13602.6 EGE02350.1 - 5.4e-13 50.1 0.0 8.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGE02350.1 - 7.2e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.32 EGE02351.1 - 2.1e-23 82.2 20.9 6.1e-06 26.9 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 EGE02351.1 - 4.2e-09 36.2 0.1 7.9e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like PQQ PF01011.21 EGE02351.1 - 1.9e-05 24.4 0.0 1.4 9.0 0.0 3.8 3 0 0 3 3 3 2 PQQ enzyme repeat F-box PF00646.33 EGE02351.1 - 3.3e-05 23.6 0.1 6.7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EGE02351.1 - 0.00011 21.9 0.1 0.35 10.4 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 EGE02351.1 - 0.0052 17.0 0.8 9.3 6.6 0.0 4.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 EGE02351.1 - 0.039 13.4 0.1 0.55 9.6 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) STE PF02200.16 EGE02351.1 - 0.04 14.3 0.1 0.72 10.3 0.0 2.4 2 0 0 2 2 2 0 STE like transcription factor F-box_4 PF15966.5 EGE02351.1 - 0.082 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 EGE02351.1 - 0.09 11.7 0.1 3.7 6.4 0.0 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain ADH_N PF08240.12 EGE02352.1 - 4.7e-26 90.8 4.4 7.2e-26 90.2 4.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE02352.1 - 4.6e-10 39.6 0.0 4.1e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGE02352.1 - 0.00014 21.3 0.2 0.00027 20.4 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHDPS PF00701.22 EGE02353.1 - 9.1e-34 116.5 0.0 3.6e-32 111.2 0.0 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 EGE02354.1 - 3.5e-08 34.3 0.2 1.4e-07 32.4 0.2 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cation_ATPase_C PF00689.21 EGE02355.1 - 1.9e-47 161.4 7.8 1.9e-47 161.4 7.8 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGE02355.1 - 1.4e-35 122.4 0.0 1.4e-35 122.4 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGE02355.1 - 7.8e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE02355.1 - 1.8e-16 61.1 1.4 8e-16 59.0 1.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE02355.1 - 2.8e-08 33.3 0.2 2.1e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGE02355.1 - 3.1e-05 23.8 0.0 0.0014 18.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1774 PF08611.10 EGE02355.1 - 0.055 13.8 4.7 0.26 11.6 0.2 2.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Ferlin_C PF16165.5 EGE02355.1 - 0.22 11.5 1.8 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Ferlin C-terminus P16-Arc PF04699.14 EGE02356.1 - 1.5e-46 158.6 0.0 1.7e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.12 EGE02357.1 - 9.3e-09 35.8 0.0 2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02357.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02357.1 - 2.2e-06 28.3 0.0 6.5e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02357.1 - 0.00012 22.8 0.0 0.00024 21.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02357.1 - 0.001 18.9 0.0 0.004 17.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE02357.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GhoS PF11080.8 EGE02357.1 - 0.17 11.9 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Endoribonuclease GhoS Dynactin_p62 PF05502.13 EGE02358.1 - 3.4e-208 692.2 0.1 4.1e-208 692.0 0.1 1.0 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 EGE02359.1 - 1.2e-78 263.1 0.2 1.4e-78 262.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Vezatin PF12632.7 EGE02359.1 - 0.016 14.6 0.8 2.1 7.6 0.0 2.0 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes EntA_Immun PF08951.10 EGE02359.1 - 0.04 14.3 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Enterocin A Immunity XFP_N PF09364.10 EGE02360.1 - 2.2e-149 497.2 0.0 3.3e-149 496.6 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EGE02360.1 - 1.5e-76 256.4 0.0 2.3e-76 255.8 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EGE02360.1 - 2.6e-63 212.9 0.1 4.2e-63 212.2 0.1 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase vATP-synt_AC39 PF01992.16 EGE02360.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Acetate_kinase PF00871.17 EGE02361.1 - 8.7e-87 291.3 0.0 8.1e-86 288.2 0.0 1.9 1 1 0 1 1 1 1 Acetokinase family MCM6_C PF18263.1 EGE02361.1 - 0.052 13.8 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain DUF1467 PF07330.12 EGE02363.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Ras PF00071.22 EGE02364.1 - 2.3e-55 186.6 0.0 2.9e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE02364.1 - 5.9e-34 116.9 0.0 8.3e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE02364.1 - 6.1e-13 48.6 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE02364.1 - 5.3e-05 22.8 0.0 9.2e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGE02364.1 - 0.00028 20.9 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGE02364.1 - 0.00029 20.3 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGE02364.1 - 0.0013 19.1 0.0 0.0021 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 EGE02365.1 - 4.3e-39 134.5 0.0 7.9e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02365.1 - 4.1e-26 91.8 0.0 9.5e-26 90.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGE02365.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE02365.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Macoilin PF09726.9 EGE02366.1 - 1.3 7.5 15.6 2.3 6.7 15.6 1.3 1 0 0 1 1 1 0 Macoilin family Sugar_tr PF00083.24 EGE02368.1 - 6.7e-81 272.5 29.6 7.7e-81 272.2 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE02368.1 - 9.1e-13 47.8 40.0 9.3e-09 34.7 14.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CelTOS PF18659.1 EGE02369.1 - 0.033 14.6 0.2 0.054 13.9 0.2 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites DUF4451 PF14616.6 EGE02370.1 - 2.9e-21 75.9 0.1 4.8e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) TPR_1 PF00515.28 EGE02371.1 - 1.8e-35 119.3 9.9 8.9e-07 28.5 0.0 7.6 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02371.1 - 3.1e-34 114.3 11.4 1.3e-06 28.0 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 EGE02371.1 - 1.1e-26 92.7 4.3 1.6e-26 92.2 1.2 2.9 3 0 0 3 3 3 1 DnaJ domain TPR_19 PF14559.6 EGE02371.1 - 1.3e-24 86.4 11.1 9.6e-06 26.0 0.2 6.1 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGE02371.1 - 1.7e-21 75.0 8.1 0.00032 21.3 0.0 8.8 3 3 6 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGE02371.1 - 1.2e-20 72.9 11.7 1.8e-05 24.3 0.0 7.4 4 2 3 7 7 7 4 TPR repeat TPR_17 PF13431.6 EGE02371.1 - 2e-18 65.3 10.1 0.0014 18.9 0.2 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02371.1 - 2.9e-18 64.5 6.7 0.006 16.7 0.0 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGE02371.1 - 3.3e-14 51.8 8.2 0.05 13.7 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGE02371.1 - 3.5e-14 52.8 8.4 0.023 15.0 0.0 5.7 4 1 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE02371.1 - 4.3e-13 49.3 2.6 0.00047 20.3 0.1 4.2 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGE02371.1 - 6.9e-13 48.6 2.6 0.0011 19.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02371.1 - 4.9e-12 46.3 26.6 0.0017 18.9 0.0 6.5 6 1 2 8 8 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGE02371.1 - 6.9e-10 38.9 11.2 0.0021 18.6 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGE02371.1 - 1.4e-08 34.4 3.7 0.013 14.7 0.0 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 EGE02371.1 - 5.6e-07 30.1 4.2 0.00047 20.6 0.3 4.3 3 2 0 3 3 3 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EGE02371.1 - 1.9e-06 27.8 4.6 0.099 12.7 0.0 4.9 2 1 3 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGE02371.1 - 1.3e-05 24.9 11.7 0.18 11.7 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGE02371.1 - 0.0001 22.6 5.2 6.8 7.1 0.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGE02371.1 - 0.00025 20.2 0.0 0.12 11.3 0.0 2.5 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_E PF04733.14 EGE02371.1 - 0.002 17.6 0.4 7.6 5.9 0.1 3.2 3 0 0 3 3 3 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 EGE02371.1 - 0.0078 16.2 0.3 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_MalT PF17874.1 EGE02371.1 - 0.018 14.4 0.7 0.35 10.2 0.1 2.4 2 1 0 2 2 2 0 MalT-like TPR region TPR_21 PF09976.9 EGE02371.1 - 0.074 12.7 4.9 16 5.1 0.0 4.6 2 2 2 5 5 5 0 Tetratricopeptide repeat-like domain Wzy_C_2 PF11846.8 EGE02371.1 - 0.24 11.3 5.7 2.2 8.2 0.2 3.3 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 EGE02371.1 - 0.43 11.4 0.0 0.43 11.4 0.0 5.7 6 0 0 6 6 4 0 Tetratricopeptide repeat RPN7 PF10602.9 EGE02371.1 - 1 9.0 6.7 1.2 8.8 0.0 3.8 3 3 1 4 4 4 0 26S proteasome subunit RPN7 MIT PF04212.18 EGE02371.1 - 1.3 9.2 0.0 1.3 9.2 0.0 4.2 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain HHH_8 PF14716.6 EGE02371.1 - 2.7 8.4 7.0 1.9 8.9 0.1 3.9 5 0 0 5 5 4 0 Helix-hairpin-helix domain Osmo_CC PF08946.10 EGE02373.1 - 0.21 11.9 1.7 0.63 10.3 0.1 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil ATG16 PF08614.11 EGE02373.1 - 0.81 9.9 13.3 0.03 14.6 7.3 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 EGE02373.1 - 2.8 5.6 18.5 0.26 9.0 9.1 2.0 2 0 0 2 2 2 0 Myosin tail HEPN_RES_NTD1 PF18870.1 EGE02376.1 - 0.056 13.6 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 APH PF01636.23 EGE02381.1 - 2.3e-09 37.5 0.1 1.1e-08 35.3 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE02381.1 - 0.033 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGE02381.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Protoglobin PF11563.8 EGE02385.1 - 9.9e-52 175.0 0.0 1.2e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 Protoglobin CN_hydrolase PF00795.22 EGE02386.1 - 1e-36 126.7 0.0 1.5e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGE02386.1 - 6.2e-25 87.7 0.0 1.3e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Pkinase PF00069.25 EGE02387.1 - 6.4e-61 206.0 0.0 8.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02387.1 - 1e-34 120.0 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE02387.1 - 5e-07 29.3 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGE02387.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGE02387.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec39 PF08314.11 EGE02388.1 - 2.4e-268 892.6 0.0 2.8e-268 892.4 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 EGE02389.1 - 0.00066 19.9 0.0 0.00074 19.7 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DnaJ PF00226.31 EGE02389.1 - 0.0062 16.7 0.4 0.0085 16.2 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain COX6B PF02297.17 EGE02389.1 - 0.007 16.6 0.2 0.01 16.0 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 EGE02389.1 - 0.053 13.9 1.7 0.35 11.3 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 EGE02389.1 - 0.062 13.6 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF4407 PF14362.6 EGE02390.1 - 0.022 14.1 0.0 0.023 14.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF819 PF05684.12 EGE02390.1 - 0.082 11.9 0.0 0.094 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DUF4834 PF16118.5 EGE02390.1 - 1.3 10.0 3.7 13 6.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3535 PF12054.8 EGE02391.1 - 1.8e-127 426.2 0.0 2.7e-126 422.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGE02391.1 - 8.7e-64 215.4 0.0 2.4e-63 214.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE02391.1 - 2e-19 70.0 0.0 5.9e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGE02391.1 - 7.4e-18 63.1 8.9 0.0014 18.7 0.2 9.6 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 EGE02391.1 - 7e-07 29.5 5.1 0.0023 18.3 0.1 6.3 6 1 0 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGE02391.1 - 4.2e-06 27.3 0.2 0.56 10.8 0.0 4.2 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGE02391.1 - 0.00038 20.1 0.0 0.11 12.0 0.0 3.8 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 EGE02391.1 - 0.0011 19.5 7.8 7.7 7.1 0.0 7.1 6 1 2 8 8 8 1 HEAT-like repeat TAF6_C PF07571.13 EGE02391.1 - 0.0022 18.2 0.1 0.35 11.2 0.0 4.4 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGE02391.1 - 0.043 14.0 0.0 0.81 9.9 0.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Erythro_esteras PF05139.14 EGE02393.1 - 3.4e-125 418.4 2.0 4e-125 418.2 2.0 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 EGE02393.1 - 0.00021 21.4 0.2 0.22 11.5 0.1 2.3 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN Scs3p PF10261.9 EGE02395.1 - 9.1e-72 241.5 1.8 1.3e-71 241.0 1.8 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Zn_clus PF00172.18 EGE02396.1 - 0.0067 16.5 12.3 0.013 15.6 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TYA PF01021.19 EGE02396.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 TYA transposon protein DUF3262 PF11660.8 EGE02397.1 - 0.1 13.0 2.7 0.25 11.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) Glyco_hydro_3_C PF01915.22 EGE02399.1 - 4.9e-52 176.9 0.0 7.7e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGE02399.1 - 2.4e-39 135.6 0.0 5.2e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGE02399.1 - 3.4e-12 46.3 0.0 6.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_47 PF01532.20 EGE02400.1 - 1.2e-181 604.6 0.0 1.4e-181 604.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EGE02400.1 - 0.00068 18.3 0.0 0.053 12.0 0.0 2.3 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 DUF5615 PF18480.1 EGE02400.1 - 0.14 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) SKG6 PF08693.10 EGE02401.1 - 0.00025 20.4 0.1 0.00046 19.5 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 EGE02401.1 - 0.015 15.1 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4381 PF14316.6 EGE02401.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sensor PF13796.6 EGE02401.1 - 0.12 12.5 0.2 0.24 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative sensor Mfa_like_2 PF15415.6 EGE02401.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Fimbrillin-like Fungal_trans PF04082.18 EGE02402.1 - 2.2e-24 85.9 0.6 7.3e-24 84.2 0.0 2.2 2 1 0 2 2 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02402.1 - 6.6e-09 35.8 10.8 1.2e-08 35.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EGE02402.1 - 0.00024 21.2 15.9 0.00024 21.2 15.9 2.6 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 EGE02402.1 - 0.049 13.8 14.3 0.04 14.1 7.3 2.4 2 0 0 2 2 2 0 DDHD domain DUF4407 PF14362.6 EGE02402.1 - 0.48 9.7 11.4 0.86 8.9 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 EGE02402.1 - 0.96 9.0 49.3 0.038 13.6 29.4 2.4 2 0 0 2 2 2 0 Spt20 family AAT PF03417.16 EGE02402.1 - 1.1 8.9 5.5 1.8 8.2 3.4 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase PAT1 PF09770.9 EGE02402.1 - 1.3 7.2 33.2 1.1 7.5 15.4 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.6 EGE02402.1 - 1.4 9.3 5.4 34 4.9 4.7 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Band_3_cyto PF07565.13 EGE02402.1 - 1.8 8.3 17.7 0.084 12.7 4.9 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EPL1 PF10513.9 EGE02402.1 - 2.6 8.4 16.6 0.17 12.2 6.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Man-6-P_recep PF02157.15 EGE02403.1 - 3.9e-12 45.8 0.0 2.4e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EGE02403.1 - 4.1e-09 36.7 0.1 5.9e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EGE02403.1 - 1.4e-07 31.7 0.2 4.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Roughex PF06020.11 EGE02403.1 - 8.2 5.4 7.1 31 3.5 5.1 2.0 2 0 0 2 2 2 0 Drosophila roughex protein ERG4_ERG24 PF01222.17 EGE02404.1 - 2.8e-147 490.9 0.4 3.3e-147 490.7 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGE02404.1 - 0.00022 20.8 0.4 0.00055 19.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 EGE02404.1 - 4.6 7.2 4.4 0.9 9.5 0.4 1.8 2 0 0 2 2 2 0 Ferlin C-terminus A_deamin PF02137.18 EGE02405.1 - 6.1e-24 85.1 0.0 1.8e-21 77.0 0.0 2.5 1 1 0 2 2 2 2 Adenosine-deaminase (editase) domain APOBEC_N PF08210.11 EGE02405.1 - 0.0054 16.6 0.4 0.018 14.9 0.2 1.8 2 0 0 2 2 2 1 APOBEC-like N-terminal domain SF3b10 PF07189.11 EGE02407.1 - 7.2e-34 115.7 0.0 8.4e-34 115.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Mgr1 PF08602.10 EGE02411.1 - 0.058 12.2 2.4 0.072 11.9 2.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Seryl_tRNA_N PF02403.22 EGE02411.1 - 0.42 10.8 12.8 0.3 11.3 11.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAUS6_N PF14661.6 EGE02411.1 - 1.9 8.0 11.3 2.6 7.5 11.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Coiled-coil_56 PF09813.9 EGE02411.1 - 6.8 6.8 11.1 3.7 7.7 9.0 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Atg14 PF10186.9 EGE02411.1 - 9.3 5.2 11.5 13 4.8 11.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 p450 PF00067.22 EGE02412.1 - 3.1e-58 197.6 0.0 3.8e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGE02413.1 - 7.1e-30 104.2 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NT-C2 PF10358.9 EGE02414.1 - 6.1e-28 97.4 0.0 8e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.6 EGE02415.1 - 4e-34 118.4 0.0 7.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator EcoEI_R_C PF08463.10 EGE02415.1 - 0.0028 17.8 0.3 0.0057 16.8 0.3 1.4 1 0 0 1 1 1 1 EcoEI R protein C-terminal Myotub-related PF06602.14 EGE02416.1 - 6.8e-144 479.1 0.0 8.4e-144 478.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGE02416.1 - 0.0012 18.9 0.2 0.0038 17.2 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGE02416.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.20 EGE02417.1 - 3.7e-25 88.3 0.1 2e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGE02417.1 - 6.5e-12 45.1 0.1 1.2e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EGE02417.1 - 0.036 13.9 0.1 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EGE02417.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 tRNA_synthFbeta PF17759.1 EGE02418.1 - 8.6e-50 169.1 0.0 1.2e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGE02418.1 - 2.8e-29 101.1 0.3 3.4e-28 97.7 0.1 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGE02418.1 - 1.1e-24 87.1 0.1 2.1e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGE02418.1 - 4.4e-18 65.3 0.0 1.5e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF2740 PF10872.8 EGE02418.1 - 0.059 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) HEAT PF02985.22 EGE02419.1 - 1.6e-42 139.8 11.7 0.015 15.5 0.1 12.9 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 EGE02419.1 - 1.7e-37 127.6 4.0 9.6e-10 38.7 0.0 8.2 4 2 3 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 EGE02419.1 - 5.4e-15 55.5 7.5 6.1e-05 23.4 0.0 8.8 8 2 2 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGE02419.1 - 2.5e-12 47.2 2.9 0.00028 21.4 0.1 7.4 6 2 4 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGE02419.1 - 4.9e-11 42.9 9.8 0.0023 18.0 0.3 6.0 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGE02419.1 - 2.2e-08 33.1 5.9 2.9e-07 29.4 1.0 3.6 2 1 2 4 4 4 1 Adaptin N terminal region RTP1_C1 PF10363.9 EGE02419.1 - 1.7e-05 24.9 6.1 1 9.6 0.3 4.9 4 1 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGE02419.1 - 0.0092 15.6 3.0 3.6 7.1 0.1 4.4 4 2 2 6 6 6 1 CLASP N terminal Proteasom_PSMB PF10508.9 EGE02419.1 - 0.012 14.2 4.3 0.68 8.4 1.5 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit TetR_C_16 PF17920.1 EGE02419.1 - 0.094 13.0 0.4 18 5.6 0.0 3.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IFRD PF05004.13 EGE02419.1 - 0.38 9.8 1.6 2.3 7.2 0.0 3.0 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Ecm29 PF13001.7 EGE02419.1 - 0.68 8.5 4.1 14 4.2 0.1 3.6 4 1 1 5 5 5 0 Proteasome stabiliser Arm PF00514.23 EGE02419.1 - 0.69 10.1 7.4 2.9 8.0 0.0 4.9 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EGE02419.1 - 2.4 6.9 6.2 1.2 7.9 1.5 2.8 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) Glyco_transf_8 PF01501.20 EGE02420.1 - 4.1e-26 92.1 0.0 8.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF3072 PF11272.8 EGE02420.1 - 0.054 13.4 0.4 0.14 12.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Abhydrolase_6 PF12697.7 EGE02421.1 - 9.6e-15 55.8 0.8 1.5e-13 51.9 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE02421.1 - 4.9e-12 46.0 0.0 2.9e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE02421.1 - 0.00085 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 EGE02421.1 - 0.021 15.2 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydrolase_2 PF02230.16 EGE02421.1 - 0.1 12.4 0.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Med10 PF09748.9 EGE02421.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Glyco_transf_90 PF05686.12 EGE02422.1 - 9.7e-16 57.7 10.3 2.1e-12 46.7 7.9 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 CDO_I PF05995.12 EGE02424.1 - 2.7e-40 137.4 0.0 3.3e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EGE02424.1 - 8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO MMR_HSR1_Xtn PF16897.5 EGE02425.1 - 2.2e-39 133.7 0.8 5.2e-39 132.5 0.3 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGE02425.1 - 1.3e-20 73.6 0.1 3.9e-20 72.0 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGE02425.1 - 2.2e-19 69.3 0.0 5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGE02425.1 - 4.1e-09 36.2 0.1 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGE02425.1 - 0.00099 19.2 0.1 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 EGE02425.1 - 0.0075 15.3 0.1 0.019 14.0 0.1 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EGE02425.1 - 0.15 11.5 0.3 7.8 5.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGE02425.1 - 0.16 11.9 1.0 3.8 7.4 0.1 2.7 2 1 1 3 3 3 0 RsgA GTPase HTH_Tnp_Tc5 PF03221.16 EGE02426.1 - 7.5e-14 51.5 0.1 1.7e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EGE02426.1 - 8.1e-06 25.4 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 EGE02426.1 - 0.0053 16.7 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 EGE02426.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 EGE02426.1 - 0.017 14.7 0.1 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF3289 PF11692.8 EGE02426.1 - 0.053 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) HTH_38 PF13936.6 EGE02426.1 - 0.061 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EGE02426.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.6 EGE02426.1 - 0.12 12.2 0.1 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain PXA PF02194.15 EGE02427.1 - 4.6e-45 153.8 0.0 1.5e-44 152.2 0.0 1.8 2 0 0 2 2 2 1 PXA domain Neisseria_TspB PF05616.13 EGE02427.1 - 1.2 7.6 3.3 2 6.8 3.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein IU_nuc_hydro PF01156.19 EGE02428.1 - 2.8e-77 260.3 0.1 3.2e-77 260.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MR_MLE_C PF13378.6 EGE02429.1 - 1.3e-57 194.9 0.0 1.7e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGE02429.1 - 1.5e-17 63.8 0.0 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF4213 PF13938.6 EGE02429.1 - 0.09 13.0 0.0 2.3 8.5 0.0 2.8 2 1 0 2 2 2 0 Putative heavy-metal chelation Vac_ImportDeg PF09783.9 EGE02430.1 - 1.8e-39 135.1 0.4 4.6e-39 133.8 0.2 1.8 2 0 0 2 2 2 1 Vacuolar import and degradation protein Ribosomal_L7Ae PF01248.26 EGE02431.1 - 3.3e-26 90.8 0.5 4.4e-26 90.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EGE02431.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ank_2 PF12796.7 EGE02432.1 - 2e-24 86.0 0.7 7.5e-13 48.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE02432.1 - 2.3e-20 72.4 0.8 1.6e-09 37.8 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE02432.1 - 1.8e-14 53.9 0.0 3.1e-07 30.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGE02432.1 - 1.4e-13 50.6 0.8 0.0011 19.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGE02432.1 - 6.7e-12 44.5 0.7 0.00015 21.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Steroid_dh PF02544.16 EGE02433.1 - 1.4e-09 38.1 1.3 1.4e-09 38.1 1.3 2.3 1 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase SLATT_fungal PF18142.1 EGE02433.1 - 0.45 10.5 2.3 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Rax2 PF12768.7 EGE02435.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 EGE02435.1 - 0.16 11.4 1.5 0.44 10.0 1.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rotamase_3 PF13616.6 EGE02436.1 - 5.4e-16 59.2 0.1 1.1e-15 58.2 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EGE02436.1 - 2.8e-14 53.9 0.0 4.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EGE02436.1 - 2.6e-05 25.0 0.1 4.1e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.11 EGE02437.1 - 8e-43 146.8 15.0 2.1e-42 145.4 15.0 1.6 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EGE02437.1 - 1.3e-07 31.2 0.2 0.00086 18.6 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 EGE02437.1 - 1.5e-05 25.2 34.3 0.00031 20.9 12.3 3.8 3 1 0 3 3 3 2 EamA-like transporter family Sen15 PF09631.10 EGE02438.1 - 3e-15 56.3 0.0 1.5e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 Sen15 protein 4HBT_3 PF13622.6 EGE02438.1 - 0.081 13.2 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily VASt PF16016.5 EGE02439.1 - 7.5e-37 127.1 0.4 2e-36 125.7 0.2 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EGE02439.1 - 1.7e-15 57.4 0.2 2.8e-15 56.7 0.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGE02439.1 - 9.6e-08 32.5 0.0 3.9e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 EGE02439.1 - 0.00083 19.2 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 EGE02439.1 - 0.0062 16.2 1.2 0.011 15.4 1.2 1.3 1 0 0 1 1 1 1 BAR domain Kri1 PF05178.12 EGE02440.1 - 2.2e-30 105.2 20.5 2.2e-30 105.2 20.5 5.4 6 1 0 6 6 6 1 KRI1-like family Kri1_C PF12936.7 EGE02440.1 - 2.7e-29 101.2 0.2 2.7e-29 101.2 0.2 3.9 2 2 2 4 4 4 1 KRI1-like family C-terminal Mito_carr PF00153.27 EGE02441.1 - 1e-67 224.1 5.8 6.7e-25 86.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.9 EGE02443.1 - 1.1e-37 127.9 0.0 1.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein APH PF01636.23 EGE02445.1 - 4.6e-16 59.5 0.0 1.9e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE02445.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family PTS_2-RNA PF01885.16 EGE02446.1 - 1.8e-63 213.9 0.0 2.2e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zinc_ribbon_16 PF17034.5 EGE02447.1 - 3.3e-25 88.7 11.0 7e-25 87.7 11.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EGE02447.1 - 1.6e-05 24.4 7.0 1.6e-05 24.4 7.0 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EGE02447.1 - 0.94 9.8 10.7 0.092 13.0 5.4 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGE02447.1 - 1.8 8.5 8.2 0.12 12.2 0.9 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Efg1 PF10153.9 EGE02448.1 - 3.9e-32 111.0 12.9 3.9e-32 111.0 12.9 2.4 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF573 PF04504.14 EGE02448.1 - 0.036 14.7 3.1 0.036 14.7 3.1 3.3 2 1 2 4 4 4 0 Protein of unknown function, DUF573 MCM3AP_GANP PF16769.5 EGE02448.1 - 9.5 4.3 10.8 14 3.8 10.8 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP LRR_6 PF13516.6 EGE02449.1 - 5.6e-13 47.8 13.3 0.0032 17.4 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich repeat F-box-like PF12937.7 EGE02449.1 - 6.7e-11 41.9 0.2 1.6e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE02449.1 - 6.3e-10 38.7 0.4 1.7e-09 37.3 0.4 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EGE02449.1 - 9.6e-06 25.9 21.3 0.00014 22.2 1.2 5.4 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGE02449.1 - 0.0023 18.2 19.9 0.46 11.2 0.4 7.0 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 EGE02449.1 - 0.095 12.5 4.2 13 5.6 0.1 4.1 4 1 0 4 4 4 0 Leucine rich repeat PRANC PF09372.10 EGE02449.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Pkinase PF00069.25 EGE02450.1 - 4.1e-55 187.0 0.0 6.3e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02450.1 - 8.6e-20 71.1 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE02450.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE02450.1 - 0.00015 20.9 0.0 0.00015 20.9 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGE02450.1 - 0.00044 20.2 0.1 0.0018 18.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE02450.1 - 0.0063 15.3 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGE02450.1 - 0.0067 16.0 0.3 0.015 14.9 0.3 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGE02450.1 - 0.073 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PAS_9 PF13426.7 EGE02450.1 - 0.11 12.7 0.0 7.7 6.8 0.0 2.8 2 0 0 2 2 2 0 PAS domain RabGAP-TBC PF00566.18 EGE02452.1 - 3.7e-30 105.2 1.0 1.1e-29 103.7 1.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RAP1 PF07218.11 EGE02452.1 - 5.7 5.1 8.3 8 4.6 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5102 PF17104.5 EGE02453.1 - 0.081 13.0 4.5 0.6 10.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Yippee-Mis18 PF03226.14 EGE02454.1 - 1.3e-13 51.1 1.2 1.8e-12 47.4 1.2 2.0 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.15 EGE02454.1 - 0.059 13.3 3.4 0.18 11.7 3.4 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII ADH_N PF08240.12 EGE02455.1 - 2.9e-29 101.2 1.0 4.8e-29 100.4 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE02455.1 - 1.7e-17 63.6 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGE02455.1 - 9.6e-06 25.2 0.0 2.1e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGE02455.1 - 0.0076 17.3 0.0 0.014 16.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EGE02455.1 - 0.026 14.4 0.4 0.095 12.7 0.4 2.1 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 EGE02455.1 - 0.041 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Dehydratase_hem PF13816.6 EGE02456.1 - 4.9e-115 384.2 0.0 5.7e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 EGE02456.1 - 2e-08 34.6 0.1 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) KH_1 PF00013.29 EGE02457.1 - 4.4e-41 138.6 9.0 6.3e-17 61.2 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGE02457.1 - 4.1e-10 39.3 7.5 0.0012 18.6 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGE02457.1 - 2.8e-09 36.7 3.2 0.025 14.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGE02457.1 - 0.00091 19.3 6.8 0.29 11.3 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ECF-ribofla_trS PF07155.12 EGE02457.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component Epimerase PF01370.21 EGE02458.1 - 4.9e-09 36.0 0.1 0.00023 20.7 0.1 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGE02458.1 - 0.00017 20.7 0.0 0.18 10.8 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGE02458.1 - 0.00022 20.7 0.0 0.00075 19.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGE02458.1 - 0.00054 19.2 0.1 0.0055 15.9 0.1 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EGE02458.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EGE02458.1 - 0.005 16.4 0.1 0.053 13.1 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EGE02458.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF3155 PF11352.8 EGE02458.1 - 0.16 12.4 0.0 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) Gp_dh_C PF02800.20 EGE02458.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DSBA PF01323.20 EGE02459.1 - 5.4e-36 124.2 0.0 6.1e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGE02459.1 - 0.011 15.9 0.1 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin GRAS PF03514.14 EGE02459.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family Pkinase PF00069.25 EGE02460.1 - 4.9e-25 88.4 0.0 1.7e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02460.1 - 1e-07 31.6 0.0 1.2e-06 28.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase ABC2_membrane PF01061.24 EGE02462.1 - 9.1e-37 126.5 27.0 6.1e-29 101.0 15.1 3.9 3 1 0 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.27 EGE02462.1 - 1.4e-24 87.2 0.0 3.2e-15 56.8 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGE02462.1 - 1.8e-07 31.0 0.2 1.8e-07 31.0 0.2 3.4 4 0 0 4 4 4 2 CDR ABC transporter AAA_25 PF13481.6 EGE02462.1 - 3e-05 23.7 0.3 0.0001 21.9 0.3 1.9 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGE02462.1 - 4.8e-05 23.3 0.1 0.0045 16.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EGE02462.1 - 0.00041 20.2 0.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE02462.1 - 0.0011 18.6 1.0 0.016 14.9 0.2 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE02462.1 - 0.0059 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGE02462.1 - 0.023 14.2 0.0 0.29 10.5 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGE02462.1 - 0.023 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE02462.1 - 0.03 14.5 0.1 0.082 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.6 EGE02462.1 - 0.094 13.3 0.0 0.26 11.9 0.0 1.8 1 0 0 1 1 1 0 ABC-transporter N-terminal DSPc PF00782.20 EGE02468.1 - 1.8e-24 86.1 0.0 4.4e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE02468.1 - 0.09 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Beta-lactamase PF00144.24 EGE02469.1 - 5.6e-46 157.3 0.0 7.2e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase ABC_membrane PF00664.23 EGE02470.1 - 2e-100 336.0 38.7 2.1e-55 188.3 16.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE02470.1 - 2.5e-71 238.6 0.0 1.4e-34 119.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE02470.1 - 1.9e-16 60.2 6.3 2.9e-05 23.6 0.2 4.6 4 1 1 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGE02470.1 - 1.5e-10 41.7 4.3 0.001 19.5 1.6 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 EGE02470.1 - 1.3e-08 35.0 0.1 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EGE02470.1 - 1.6e-07 30.5 0.5 0.0061 15.4 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EGE02470.1 - 1.7e-07 31.3 0.0 0.0061 16.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGE02470.1 - 5.1e-07 29.3 0.2 0.025 14.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGE02470.1 - 2.3e-06 27.6 0.3 0.0043 16.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGE02470.1 - 3.4e-06 27.4 0.4 0.012 15.9 0.1 3.5 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGE02470.1 - 5.2e-06 25.9 0.1 0.12 11.7 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 EGE02470.1 - 3.1e-05 23.8 0.5 0.13 12.0 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EGE02470.1 - 0.00011 22.2 0.2 0.4 10.7 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGE02470.1 - 0.00013 22.4 0.9 16 5.9 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 EGE02470.1 - 0.00042 19.6 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EGE02470.1 - 0.002 17.6 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 EGE02470.1 - 0.0021 18.6 0.0 3.8 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGE02470.1 - 0.0027 17.9 3.2 3 8.2 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGE02470.1 - 0.003 17.3 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGE02470.1 - 0.0043 17.6 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGE02470.1 - 0.0045 17.1 0.0 0.55 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGE02470.1 - 0.0068 15.6 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EGE02470.1 - 0.0091 15.9 0.1 1.5 8.7 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain DUF87 PF01935.17 EGE02470.1 - 0.024 14.7 0.3 17 5.4 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_24 PF13479.6 EGE02470.1 - 0.029 14.1 0.2 0.74 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGE02470.1 - 0.034 14.4 0.1 3.7 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGE02470.1 - 0.036 13.6 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGE02470.1 - 0.037 14.1 2.0 1.7 8.8 0.1 3.3 3 1 0 3 3 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGE02470.1 - 0.057 13.8 0.1 8.2 6.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EGE02470.1 - 0.065 13.3 1.6 36 4.4 0.0 4.5 5 0 0 5 5 5 0 Dynamin family APS_kinase PF01583.20 EGE02470.1 - 0.11 12.4 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AMP-binding PF00501.28 EGE02471.1 - 1.2e-130 435.9 0.0 3.8e-65 220.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGE02471.1 - 2e-94 316.9 0.0 1.3e-35 123.0 0.0 5.9 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.25 EGE02471.1 - 2.3e-35 120.8 0.2 1.9e-12 47.4 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE02471.1 - 0.0013 19.6 0.0 0.19 12.8 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HpaB PF03241.13 EGE02471.1 - 0.014 14.5 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Cyclophil_like2 PF18050.1 EGE02471.1 - 0.017 15.1 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Cyclophilin-like family Methyltransf_31 PF13847.6 EGE02472.1 - 7.4e-14 51.8 0.0 1.7e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02472.1 - 2.5e-07 31.3 0.0 3.2e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02472.1 - 9.1e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02472.1 - 4.9e-05 23.9 0.0 0.00014 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02472.1 - 0.0039 17.9 0.0 0.0087 16.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EGE02472.1 - 0.026 14.1 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EGE02472.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EGE02473.1 - 0.00054 19.7 0.0 0.084 12.6 0.0 2.2 1 1 0 2 2 2 2 Lysine methyltransferase zf-C2H2 PF00096.26 EGE02474.1 - 0.012 16.1 3.7 0.042 14.3 3.7 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE02474.1 - 0.57 11.2 3.3 2 9.5 3.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1635 PF07795.11 EGE02474.1 - 7.2 6.4 7.9 3.9 7.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) PHD PF00628.29 EGE02475.1 - 5.6e-06 26.2 9.6 5.6e-06 26.2 9.6 1.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 EGE02475.1 - 0.13 12.5 1.0 0.31 11.3 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain BAG PF02179.16 EGE02477.1 - 5.4e-09 36.4 0.1 8.7e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 BAG domain LMBR1 PF04791.16 EGE02478.1 - 7.7e-53 180.2 0.2 8.9e-53 179.9 0.2 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Ribosomal_60s PF00428.19 EGE02478.1 - 0.0055 17.3 2.9 0.014 16.0 2.9 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein CDC45 PF02724.14 EGE02479.1 - 1.2 7.4 3.7 1.1 7.4 3.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Med15_fungi PF05397.12 EGE02480.1 - 1.4e-25 89.7 0.2 1.4e-25 89.7 0.2 5.6 5 1 1 6 6 6 1 Mediator complex subunit 15 DUF3385 PF11865.8 EGE02480.1 - 0.31 11.0 8.7 0.77 9.6 0.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) EamA PF00892.20 EGE02481.1 - 1e-08 35.5 26.0 8.7e-06 26.0 2.9 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGE02481.1 - 1.1e-08 34.7 0.1 1.9e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EGE02481.1 - 8.2e-05 21.9 8.0 0.00017 20.9 8.0 1.6 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EGE02481.1 - 0.00077 18.9 6.8 0.001 18.5 0.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family DMT_6 PF04342.12 EGE02481.1 - 0.56 10.4 5.6 3.8 7.8 1.6 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) MBOAT PF03062.19 EGE02482.1 - 1.5e-31 110.0 23.7 2e-29 103.0 16.0 2.1 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 EGE02482.1 - 0.095 13.3 0.0 0.59 10.8 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Adaptin_N PF01602.20 EGE02483.1 - 6.4e-141 470.5 0.2 7.5e-141 470.2 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGE02483.1 - 2.8e-21 75.9 0.0 7.2e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EGE02483.1 - 5.2e-09 36.4 0.5 0.0089 16.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGE02483.1 - 1.4e-08 35.0 2.5 0.00022 21.3 0.0 4.0 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGE02483.1 - 0.00047 20.2 2.1 6.5 7.3 0.1 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EGE02483.1 - 0.0041 17.6 0.1 22 5.7 0.0 4.7 3 1 0 3 3 3 1 HEAT-like repeat Arm PF00514.23 EGE02483.1 - 0.038 14.0 0.1 99 3.2 0.1 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 EGE02483.1 - 0.063 13.1 0.5 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain DnaJ PF00226.31 EGE02487.1 - 3.9e-21 75.0 1.0 8.6e-21 73.8 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain PRP38_assoc PF12871.7 EGE02487.1 - 2.4e-05 24.8 34.8 2.4e-05 24.8 34.8 6.2 4 1 1 6 6 6 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Mitoc_mL59 PF18126.1 EGE02488.1 - 0.011 16.1 1.4 0.012 16.0 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Pyr_redox_2 PF07992.14 EGE02489.1 - 2.3e-35 122.2 0.0 3.4e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE02489.1 - 6.2e-15 55.5 0.0 7.8e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE02489.1 - 1e-05 24.9 0.0 5.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE02489.1 - 1.2e-05 24.6 0.0 0.00024 20.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EGE02489.1 - 0.00021 20.3 0.0 0.16 10.8 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EGE02489.1 - 0.024 13.7 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGE02489.1 - 0.041 13.5 0.0 3.7 7.0 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGE02489.1 - 0.052 13.5 0.2 62 3.6 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Eno-Rase_NADH_b PF12242.8 EGE02489.1 - 0.081 12.7 0.0 0.38 10.5 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TrkA_N PF02254.18 EGE02489.1 - 0.14 12.5 0.0 5.6 7.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Metallophos PF00149.28 EGE02490.1 - 4e-15 56.9 0.7 5.9e-15 56.3 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE02490.1 - 2e-07 31.3 0.1 9.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGE02490.1 - 0.0056 16.0 0.0 0.9 8.8 0.0 2.5 2 1 0 2 2 2 2 Metallophosphoesterase, calcineurin superfamily MutL PF13941.6 EGE02490.1 - 0.026 13.1 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 MutL protein Ribosomal_L13 PF00572.18 EGE02491.1 - 9.1e-11 42.1 0.0 6.7e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.28 EGE02492.1 - 1.2e-72 244.8 0.0 1.4e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE02492.1 - 2.4e-15 57.3 0.1 5.5e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 EGE02492.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 LysR substrate binding domain LRR_6 PF13516.6 EGE02493.1 - 3.8e-13 48.3 21.8 0.35 11.0 0.0 12.6 13 0 0 13 13 13 3 Leucine Rich repeat LRR_4 PF12799.7 EGE02493.1 - 1.8e-09 37.7 13.9 2.7 8.5 0.0 7.9 3 2 5 9 9 9 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGE02493.1 - 2.5e-09 36.9 1.4 2.5e-09 36.9 1.4 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGE02493.1 - 0.0016 18.3 8.9 0.0022 17.8 2.1 3.4 3 0 0 3 3 3 1 F-box domain CbbQ_C PF08406.10 EGE02493.1 - 0.057 13.7 0.2 22 5.4 0.0 3.5 3 0 0 3 3 3 0 CbbQ/NirQ/NorQ C-terminal Preseq_ALAS PF09029.10 EGE02493.1 - 0.078 13.5 0.2 0.33 11.4 0.1 2.1 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence LRR_8 PF13855.6 EGE02493.1 - 0.21 11.4 9.1 3.6 7.4 0.0 5.3 5 1 1 6 6 6 0 Leucine rich repeat Peptidase_M28 PF04389.17 EGE02494.1 - 7.5e-35 120.4 0.0 1.3e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP-synt_8 PF00895.20 EGE02494.1 - 0.077 13.5 0.0 0.077 13.5 0.0 4.4 5 0 0 5 5 5 0 ATP synthase protein 8 Peptidase_M20 PF01546.28 EGE02494.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Med10 PF09748.9 EGE02496.1 - 1.9e-38 131.1 0.0 3e-38 130.5 0.0 1.3 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EGE02496.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) AAA_16 PF13191.6 EGE02498.1 - 1.3e-06 28.9 0.6 5.8e-06 26.8 0.4 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGE02498.1 - 0.00017 22.0 0.0 0.026 14.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGE02498.1 - 0.0084 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2859 PF11072.8 EGE02498.1 - 0.012 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DUF815 PF05673.13 EGE02498.1 - 0.032 13.4 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGE02498.1 - 0.044 14.1 0.4 0.36 11.1 0.3 2.3 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGE02498.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EGE02498.1 - 0.076 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Metallophos PF00149.28 EGE02499.1 - 2.4e-12 47.8 0.3 4.4e-12 46.9 0.3 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE02499.1 - 6.4e-09 36.2 1.2 3.5e-08 33.8 1.2 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CLU PF13236.6 EGE02501.1 - 3.1e-74 249.5 0.0 5.2e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGE02501.1 - 1.8e-55 187.7 0.0 4.4e-55 186.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGE02501.1 - 5.3e-27 93.9 4.2 1.5e-12 47.6 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGE02501.1 - 2.9e-22 77.8 0.6 1.3e-05 24.9 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 EGE02501.1 - 1e-12 48.2 0.2 6.3e-12 45.7 0.1 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 EGE02501.1 - 8.9e-05 22.3 4.9 0.29 11.3 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02501.1 - 0.0039 17.3 4.1 0.14 12.4 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 EGE02501.1 - 0.0061 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) CDC37_M PF08565.11 EGE02501.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain TPR_17 PF13431.6 EGE02501.1 - 4.3 7.9 5.6 1.6e+02 3.0 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 EGE02504.1 - 1.1e-21 77.3 9.5 1.1e-21 77.3 9.5 2.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGE02504.1 - 2.5e-17 63.4 0.0 8.5e-15 55.2 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGE02504.1 - 4.9e-13 49.1 0.0 3.8e-11 43.0 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain GST_N_3 PF13417.6 EGE02505.1 - 1.5e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGE02505.1 - 1.1e-14 54.5 0.0 1.9e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE02505.1 - 5.9e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE02505.1 - 1.8e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE02505.1 - 4.5e-10 39.6 0.0 7.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE02505.1 - 7.7e-08 32.3 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.6 EGE02505.1 - 0.15 12.5 0.1 3.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 SF1-HH PF16275.5 EGE02506.1 - 1.2e-43 148.0 1.0 3.1e-43 146.7 1.0 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EGE02506.1 - 1.4e-11 43.9 11.1 2e-05 24.4 3.6 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EGE02506.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EGE02506.1 - 2.5e-06 27.3 6.2 0.0014 18.6 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGE02506.1 - 0.00052 19.7 4.7 0.28 11.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EGE02506.1 - 0.003 17.3 8.3 0.55 10.1 1.5 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EGE02506.1 - 0.022 14.6 0.6 0.022 14.6 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 EGE02506.1 - 4.6 7.6 7.4 0.75 10.1 3.0 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF3716 PF12511.8 EGE02507.1 - 4.3e-05 23.5 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HCO3_cotransp PF00955.21 EGE02508.1 - 1.7e-84 284.5 15.5 9.9e-45 153.3 6.9 2.0 1 1 1 2 2 2 2 HCO3- transporter family DEAD PF00270.29 EGE02509.1 - 9.6e-41 139.5 0.0 2.4e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE02509.1 - 3e-30 104.8 0.0 6.5e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE02509.1 - 0.00025 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGE02509.1 - 0.0094 14.7 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain tRNA-synt_1c PF00749.21 EGE02513.1 - 1.9e-100 335.8 0.0 2.5e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGE02513.1 - 4.4e-39 134.1 0.1 7e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EGE02513.1 - 0.00096 19.3 0.1 0.04 14.1 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE02513.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE02513.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1793 PF08760.11 EGE02514.1 - 5.6e-70 235.1 0.1 9.5e-70 234.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EGE02514.1 - 1.8e-61 206.8 1.1 1.1e-48 165.1 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EGE02514.1 - 1.8e-42 145.7 0.0 3.7e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EGE02514.1 - 0.019 14.5 0.2 0.048 13.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) CusF_Ec PF11604.8 EGE02514.1 - 0.16 11.9 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Stm1_N PF09598.10 EGE02516.1 - 3.3e-14 53.5 5.2 3.3e-14 53.5 5.2 4.6 2 2 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EGE02516.1 - 0.00023 22.0 13.0 0.00023 22.0 13.0 2.6 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family bZIP_1 PF00170.21 EGE02517.1 - 9.8e-07 28.8 7.8 2.2e-06 27.6 7.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGE02517.1 - 0.0072 16.4 7.8 0.0072 16.4 7.8 2.1 2 0 0 2 2 2 1 Basic region leucine zipper CCDC-167 PF15188.6 EGE02517.1 - 0.56 10.6 3.9 1.2 9.6 3.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 APH PF01636.23 EGE02518.1 - 0.00022 21.3 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 EGE02518.1 - 0.24 12.3 0.9 10 7.2 0.1 3.8 5 0 0 5 5 5 0 WD domain, G-beta repeat THUMP PF02926.17 EGE02519.1 - 3.9e-08 33.5 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 THUMP domain Rick_17kDa_Anti PF05433.15 EGE02520.1 - 0.11 12.4 5.7 0.3 11.0 5.7 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EGE02520.1 - 5.8 7.0 10.8 0.13 12.3 3.6 1.9 2 0 0 2 2 2 0 Glycine zipper EMG1 PF03587.14 EGE02521.1 - 5.1e-79 264.4 0.0 6e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UPF0506 PF11703.8 EGE02522.1 - 0.0048 17.2 4.8 0.0066 16.8 4.8 1.1 1 0 0 1 1 1 1 UPF0506 DUF5525 PF17663.1 EGE02522.1 - 0.016 13.3 3.7 0.015 13.4 3.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Conotoxin_I2 PF17557.2 EGE02522.1 - 0.053 13.6 8.8 0.082 13.0 8.8 1.2 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_18 PF08087.11 EGE02522.1 - 0.24 11.4 5.0 0.39 10.7 5.0 1.3 1 0 0 1 1 1 0 Conotoxin O-superfamily DEC-1_N PF04625.13 EGE02522.1 - 0.31 10.0 7.2 0.29 10.1 7.2 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5401 PF17380.2 EGE02522.1 - 0.39 8.7 1.2 0.4 8.7 1.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) XPG_I PF00867.18 EGE02523.1 - 2e-29 101.8 0.0 2e-29 101.8 0.0 1.9 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.17 EGE02523.1 - 4.7e-24 84.8 0.0 1e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EGE02523.1 - 0.00012 22.6 0.3 0.00034 21.1 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold RNA_pol_Rbc25 PF08292.12 EGE02523.1 - 0.22 11.8 0.8 0.59 10.4 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Linker_histone PF00538.19 EGE02524.1 - 2.6e-29 101.4 0.2 2.6e-29 101.4 0.2 2.4 3 1 1 4 4 4 1 linker histone H1 and H5 family SRP-alpha_N PF04086.13 EGE02524.1 - 0.049 13.5 31.5 0.067 13.1 31.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Toxin_trans PF07952.12 EGE02524.1 - 0.052 12.6 0.1 0.072 12.2 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain SAPS PF04499.15 EGE02524.1 - 0.75 8.5 8.0 1.1 8.0 8.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MAM33 PF02330.16 EGE02524.1 - 6 6.7 8.7 0.54 10.2 0.2 2.2 1 1 0 2 2 2 0 Mitochondrial glycoprotein Pkinase PF00069.25 EGE02526.1 - 2.8e-11 43.3 0.0 3.9e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02526.1 - 0.00044 19.6 0.6 0.003 16.9 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2880 PF11082.8 EGE02526.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Pkinase PF00069.25 EGE02527.1 - 9.5e-21 74.3 0.0 4.5e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02527.1 - 2e-07 30.6 0.0 9.2e-07 28.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE02527.1 - 2.4e-06 27.1 0.0 0.026 13.8 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGE02527.1 - 0.00048 19.0 0.4 0.00097 18.0 0.4 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE02527.1 - 0.006 16.5 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE02527.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PhnH PF05845.12 EGE02527.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) PIP5K PF01504.18 EGE02528.1 - 1.7e-101 339.0 0.1 1.7e-101 339.0 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PC_rep PF01851.22 EGE02530.1 - 0.00017 21.9 9.4 0.0091 16.4 0.1 4.8 5 0 0 5 5 5 2 Proteasome/cyclosome repeat ANAPC1 PF12859.7 EGE02530.1 - 0.00088 19.8 0.2 0.00088 19.8 0.2 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 Fungal_trans_2 PF11951.8 EGE02531.1 - 9.3e-60 202.4 0.2 1.9e-59 201.4 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02531.1 - 6.8e-09 35.7 7.2 1.3e-08 34.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EGE02532.1 - 4.8e-23 81.6 26.1 4.8e-23 81.6 26.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 EGE02532.1 - 0.076 13.1 0.1 0.23 11.6 0.1 1.8 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF1772 PF08592.11 EGE02532.1 - 5.6 7.3 16.1 0.63 10.3 1.9 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) HUN PF08729.10 EGE02533.1 - 1.9e-08 34.2 0.6 3.9e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 HPC2 and ubinuclein domain T3SS_TC PF06511.11 EGE02534.1 - 0.88 8.9 5.5 1.4 8.2 5.5 1.3 1 0 0 1 1 1 0 Type III secretion systems tip complex components Herpes_ICP4_C PF03585.14 EGE02535.1 - 0.00016 20.5 0.1 0.0002 20.2 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus ICP4-like protein C-terminal region RPAP1_C PF08620.10 EGE02536.1 - 9e-24 83.4 0.0 1.6e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGE02536.1 - 5e-15 55.0 6.9 5e-15 55.0 6.9 2.1 2 0 0 2 2 2 1 RPAP1-like, N-terminal ABC2_membrane PF01061.24 EGE02537.1 - 2.8e-74 249.1 61.0 2.4e-39 134.9 22.5 3.3 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EGE02537.1 - 1.2e-39 135.9 0.0 1.8e-18 67.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGE02537.1 - 3.5e-31 106.9 11.0 5.3e-26 90.3 0.0 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGE02537.1 - 2.6e-15 56.8 0.0 6.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 EGE02537.1 - 1.6e-07 31.5 0.2 0.0028 17.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGE02537.1 - 2.4e-06 27.3 0.0 5e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGE02537.1 - 2.7e-06 26.7 13.1 2.7e-06 26.7 13.1 3.6 2 2 2 4 4 4 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGE02537.1 - 4.6e-06 26.3 0.5 0.0031 17.2 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGE02537.1 - 1.6e-05 24.9 0.1 0.22 11.3 0.1 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE02537.1 - 2.3e-05 23.9 0.0 0.095 12.1 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGE02537.1 - 4.4e-05 23.4 0.1 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGE02537.1 - 5e-05 23.7 0.2 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGE02537.1 - 5.3e-05 23.8 0.0 0.00082 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGE02537.1 - 0.0015 19.1 0.0 0.073 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGE02537.1 - 0.0019 18.3 0.1 2.8 8.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EGE02537.1 - 0.0044 16.6 0.6 0.036 13.7 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EGE02537.1 - 0.0077 16.5 0.7 0.43 10.8 0.2 3.1 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EGE02537.1 - 0.0088 16.0 1.4 1.3 9.0 0.3 2.6 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 EGE02537.1 - 0.026 14.9 0.1 4.5 7.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGE02537.1 - 0.045 13.5 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 EGE02537.1 - 0.048 12.9 20.8 0.022 14.1 10.6 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_17 PF13207.6 EGE02537.1 - 0.053 14.0 0.3 0.54 10.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EGE02537.1 - 0.059 13.8 0.0 26 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Pax2_C PF12403.8 EGE02537.1 - 0.12 12.5 0.7 0.51 10.4 0.6 2.1 1 1 1 2 2 2 0 Paired-box protein 2 C terminal AAA_28 PF13521.6 EGE02537.1 - 0.14 12.4 0.2 0.39 10.9 0.2 1.8 1 0 0 1 1 1 0 AAA domain IDO PF01231.18 EGE02539.1 - 7.6e-05 21.7 0.1 0.00027 19.9 0.1 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD_binding_3 PF01494.19 EGE02540.1 - 3.1e-12 46.4 0.3 1.5e-08 34.3 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGE02540.1 - 2e-05 24.3 0.3 0.00015 21.5 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE02540.1 - 7.2e-05 22.9 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE02540.1 - 0.00012 21.4 0.1 0.16 11.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGE02540.1 - 0.00036 19.5 0.0 0.042 12.7 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase SE PF08491.10 EGE02540.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 EGE02540.1 - 0.0086 16.1 0.0 0.05 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding GnRH PF00446.17 EGE02541.1 - 1.1 9.8 3.0 3 8.4 3.0 1.7 1 0 0 1 1 1 0 Gonadotropin-releasing hormone Methyltransf_23 PF13489.6 EGE02542.1 - 8.7e-17 61.5 0.0 1.7e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02542.1 - 1.8e-08 35.0 0.0 7.5e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02542.1 - 3.2e-07 30.3 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02542.1 - 6.5e-07 30.0 0.0 1.6e-05 25.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02542.1 - 3.8e-06 27.4 0.0 1.1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE02542.1 - 0.063 12.7 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EGE02542.1 - 0.07 12.7 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 EGE02542.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGE02542.1 - 0.16 11.7 0.0 0.84 9.3 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase IFRD PF05004.13 EGE02544.1 - 4.5e-82 275.6 12.1 5.7e-82 275.2 12.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) RRN3 PF05327.11 EGE02544.1 - 0.23 10.0 13.5 0.46 9.0 4.2 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ORC6 PF05460.13 EGE02544.1 - 2.6 7.2 10.2 0.15 11.3 3.6 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RXT2_N PF08595.11 EGE02544.1 - 7.9 6.5 11.9 11 6.0 0.9 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Pkinase PF00069.25 EGE02545.1 - 5.1e-19 68.7 0.0 2.6e-11 43.4 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02545.1 - 5e-06 26.0 0.2 0.0014 18.0 0.4 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SH2_2 PF14633.6 EGE02546.1 - 2.8e-86 288.4 0.0 2.8e-86 288.4 0.0 3.0 4 0 0 4 4 4 1 SH2 domain HTH_44 PF14641.6 EGE02546.1 - 2.4e-38 131.1 6.6 8.9e-37 126.0 0.5 2.8 2 0 0 2 2 2 2 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EGE02546.1 - 1.8e-24 86.0 0.1 4.1e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 EGE02546.1 - 1.3e-18 67.4 22.3 1.3e-18 67.4 22.3 5.7 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 EGE02546.1 - 1.6e-05 25.1 0.0 4.9e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 EGE02546.1 - 0.00016 22.5 3.3 0.00016 22.5 3.3 4.5 3 2 1 4 4 4 1 HHH domain SH2 PF00017.24 EGE02546.1 - 0.00025 21.1 0.0 0.00098 19.2 0.0 2.1 2 0 0 2 2 2 1 SH2 domain DUF445 PF04286.12 EGE02546.1 - 0.0023 17.8 0.0 0.0023 17.8 0.0 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF445) Acetyltransf_3 PF13302.7 EGE02547.1 - 5.4e-22 79.0 0.0 7.2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE02547.1 - 5.4e-06 26.6 0.0 6.6e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGE02547.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein zf-CCCH PF00642.24 EGE02548.1 - 1.4e-11 44.0 9.3 1.4e-06 28.1 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE02548.1 - 1.5e-09 37.6 16.4 7.5e-06 25.8 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGE02548.1 - 2.2e-09 36.9 9.6 4.4e-06 26.4 2.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EGE02548.1 - 3.2e-06 27.8 4.1 0.0007 20.3 0.3 3.5 3 1 1 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 EGE02548.1 - 0.00013 22.1 0.1 0.00027 21.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGE02548.1 - 0.01 16.3 14.3 0.24 12.0 3.3 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TBPIP PF07106.13 EGE02549.1 - 5.8e-15 55.0 0.2 1.2e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain PspA_IM30 PF04012.12 EGE02549.1 - 0.0014 18.3 5.4 0.0014 18.3 5.4 1.9 1 1 1 2 2 2 1 PspA/IM30 family KASH_CCD PF14662.6 EGE02549.1 - 0.0083 16.0 6.7 0.012 15.4 6.7 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4140 PF13600.6 EGE02549.1 - 0.0089 16.4 5.3 0.029 14.8 1.5 2.4 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 EGE02549.1 - 0.013 15.7 3.2 2.5 8.4 1.7 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain Penicillinase_R PF03965.16 EGE02549.1 - 0.015 15.6 2.5 0.019 15.3 1.5 1.7 1 1 0 1 1 1 0 Penicillinase repressor Spc7 PF08317.11 EGE02549.1 - 0.029 13.3 7.4 0.036 12.9 7.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HutP PF09021.11 EGE02549.1 - 0.11 12.8 0.9 0.2 11.9 0.3 1.7 1 1 1 2 2 2 0 HutP TFIIE_beta PF02186.15 EGE02549.1 - 0.18 12.1 1.7 0.4 11.0 0.2 2.2 2 1 0 2 2 2 0 TFIIE beta subunit core domain DUF5320 PF17253.2 EGE02549.1 - 0.23 12.6 1.3 0.86 10.7 0.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF2721 PF11026.8 EGE02549.1 - 0.3 11.0 0.7 1.5 8.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) Csm1_N PF18504.1 EGE02549.1 - 0.31 11.4 4.8 0.26 11.7 1.3 2.6 1 1 2 3 3 3 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 EGE02549.1 - 0.32 11.4 8.2 0.65 10.4 8.2 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HalX PF08663.10 EGE02549.1 - 0.35 11.2 5.5 8.1 6.8 0.8 2.4 1 1 1 2 2 2 0 HalX domain Rho_Binding PF08912.11 EGE02549.1 - 0.41 11.5 7.8 4.8 8.1 0.3 2.8 2 1 0 2 2 2 0 Rho Binding YabA PF06156.13 EGE02549.1 - 0.54 10.9 3.8 2.8 8.6 3.8 2.2 1 1 0 1 1 1 0 Initiation control protein YabA FlxA PF14282.6 EGE02549.1 - 2.9 7.9 9.6 1.5 8.9 4.8 2.6 2 1 0 2 2 2 0 FlxA-like protein DUF5394 PF17372.2 EGE02549.1 - 3.3 7.2 9.1 0.94 9.0 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5394) Sel1 PF08238.12 EGE02550.1 - 3.5e-12 46.6 15.0 2.1e-07 31.4 0.1 5.9 6 1 0 6 6 6 3 Sel1 repeat TPR_1 PF00515.28 EGE02550.1 - 0.11 12.4 0.1 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGE02550.1 - 0.25 11.5 6.7 0.9 9.7 2.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Helicase_C_2 PF13307.6 EGE02551.1 - 1.2e-53 181.8 0.0 3.3e-53 180.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EGE02551.1 - 1.3e-45 155.2 0.4 3.3e-45 153.9 0.4 1.7 1 1 0 1 1 1 1 DEAD_2 AAA_22 PF13401.6 EGE02551.1 - 0.012 15.8 0.3 0.21 11.9 0.3 2.6 2 1 0 2 2 2 0 AAA domain MAJIN PF15077.6 EGE02551.1 - 0.041 13.7 1.1 1.9 8.2 2.1 2.7 3 0 0 3 3 3 0 Membrane-anchored junction protein Ribosomal_L27A PF00828.19 EGE02552.1 - 3.5e-22 79.5 0.0 4.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hydrolase_4 PF12146.8 EGE02553.1 - 0.01 15.1 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGE02553.1 - 0.099 12.1 0.0 6 6.3 0.0 2.2 1 1 0 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.22 EGE02554.1 - 2.6e-17 62.2 0.4 4.9e-08 32.8 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGE02554.1 - 5.2e-13 49.0 0.0 8e-07 29.0 0.0 2.9 3 0 0 3 3 3 2 PLD-like domain PX PF00787.24 EGE02554.1 - 1.1e-09 38.3 1.4 2.5e-09 37.1 0.2 2.2 2 0 0 2 2 2 1 PX domain AA_permease PF00324.21 EGE02555.1 - 4e-61 207.1 23.7 2e-60 204.7 23.7 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE02555.1 - 1.5e-26 93.2 17.7 2.1e-26 92.7 17.7 1.3 1 0 0 1 1 1 1 Amino acid permease Methyltransf_31 PF13847.6 EGE02558.1 - 2.9e-28 98.6 0.0 4.9e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02558.1 - 6.5e-19 68.4 0.4 1.5e-18 67.3 0.0 1.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02558.1 - 1.4e-16 60.9 0.3 8.2e-16 58.4 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE02558.1 - 1.2e-15 57.5 0.2 2.6e-15 56.4 0.1 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGE02558.1 - 2.5e-09 37.2 0.0 5.1e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGE02558.1 - 3e-09 37.0 0.0 6e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EGE02558.1 - 1.6e-07 32.0 0.0 2.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGE02558.1 - 5e-07 29.4 0.4 8.7e-07 28.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGE02558.1 - 2.5e-05 23.9 0.1 5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGE02558.1 - 3.4e-05 23.9 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGE02558.1 - 0.00013 21.4 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 EGE02558.1 - 0.002 17.7 1.4 0.0037 16.8 0.5 1.9 2 1 0 2 2 2 1 Histone methylation protein DOT1 UPF0020 PF01170.18 EGE02558.1 - 0.002 17.8 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_3 PF01596.17 EGE02558.1 - 0.0069 15.6 0.1 0.016 14.4 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.17 EGE02558.1 - 0.0075 15.8 0.4 0.03 13.8 0.3 2.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_15 PF09445.10 EGE02558.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EGE02558.1 - 0.026 14.4 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 EGE02558.1 - 0.034 14.1 0.1 0.47 10.5 0.1 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase FtsJ PF01728.19 EGE02558.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase bZIP_1 PF00170.21 EGE02559.1 - 0.047 13.8 5.7 0.077 13.1 5.5 1.4 1 1 0 1 1 1 0 bZIP transcription factor Snf7 PF03357.21 EGE02559.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Snf7 Peptidase_S41 PF03572.18 EGE02560.1 - 0.0044 16.6 0.0 0.0078 15.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Ras PF00071.22 EGE02561.1 - 2.7e-37 127.9 0.0 7e-24 84.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGE02561.1 - 1.5e-10 41.3 0.0 3.7e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE02561.1 - 0.016 14.6 0.0 0.063 12.7 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE02561.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGE02561.1 - 0.077 12.5 0.0 1.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGE02561.1 - 0.32 11.3 0.9 0.94 9.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.18 EGE02562.1 - 6.1e-09 35.9 10.7 9.1e-09 35.3 10.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.20 EGE02563.1 - 5.5e-58 196.6 0.0 6.5e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyoxalase_6 PF18029.1 EGE02564.1 - 4.8e-07 30.5 0.0 6.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EGE02564.1 - 6e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGE02564.1 - 0.042 13.8 0.0 0.099 12.6 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EGE02564.1 - 0.14 12.4 0.0 1.5 9.2 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily QRPTase_C PF01729.19 EGE02565.1 - 7.1e-48 162.6 0.8 2.2e-25 89.4 0.1 2.1 1 1 1 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGE02565.1 - 4.5e-23 81.1 0.0 1.3e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Mto2_bdg PF12808.7 EGE02566.1 - 2.8e-30 104.3 32.0 1.7e-19 69.8 20.1 10.0 11 1 0 11 11 11 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 EGE02566.1 - 2.3e-22 78.9 9.5 2.3e-22 78.9 9.5 11.8 8 2 5 13 13 13 2 Centrosomin N-terminal motif 1 Fib_alpha PF08702.10 EGE02566.1 - 0.0015 18.8 7.1 0.0015 18.8 7.1 7.9 4 1 4 8 8 8 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EGE02566.1 - 0.29 11.2 0.0 0.29 11.2 0.0 8.3 4 1 4 8 8 8 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 EGE02566.1 - 0.38 11.1 8.3 5.7 7.3 0.1 5.8 3 1 2 5 5 5 0 Domain of unknown function (DUF2935) Sec7 PF01369.20 EGE02567.1 - 1.7e-28 99.6 0.0 3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGE02567.1 - 6.1e-20 71.8 0.0 1.2e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain COesterase PF00135.28 EGE02570.1 - 7.1e-64 216.5 0.0 4.8e-54 184.1 0.0 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE02570.1 - 8.3e-05 22.5 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE02570.1 - 0.023 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family UNC-50 PF05216.13 EGE02571.1 - 5e-44 150.5 0.1 6.4e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 UNC-50 family FAD_binding_3 PF01494.19 EGE02573.1 - 3.8e-16 59.3 0.0 1e-09 38.2 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGE02573.1 - 3.5e-07 30.3 0.0 8.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE02573.1 - 1.3e-06 27.9 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE02573.1 - 3.1e-06 27.6 0.0 0.00065 20.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE02573.1 - 5.4e-05 22.9 0.1 9.3e-05 22.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE02573.1 - 0.0045 16.1 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PQQ PF01011.21 EGE02573.1 - 0.0082 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 PQQ enzyme repeat TrkA_N PF02254.18 EGE02573.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EGE02573.1 - 0.13 10.9 0.0 0.38 9.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EGE02573.1 - 0.18 10.8 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGE02573.1 - 0.24 10.6 0.0 1 8.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EGE02575.1 - 2.3e-34 118.9 28.2 3.7e-34 118.2 28.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGE02575.1 - 0.0041 16.5 22.7 0.75 9.0 22.7 2.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Holin_BhlA PF10960.8 EGE02575.1 - 0.15 12.1 0.1 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 BhlA holin family PP28 PF10252.9 EGE02576.1 - 9.4e-29 99.7 20.7 9.4e-29 99.7 20.7 3.9 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 MFS_1 PF07690.16 EGE02577.1 - 3.2e-17 62.5 47.8 9e-17 61.0 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 EGE02578.1 - 7e-13 48.8 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE02578.1 - 4.2e-09 36.7 0.0 7.9e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGE02578.1 - 5.6e-08 32.8 0.0 9.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE02578.1 - 4.5e-06 26.5 0.0 7.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGE02578.1 - 0.00063 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGE02578.1 - 0.036 13.8 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 EGE02578.1 - 0.048 14.3 0.0 0.06 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_20 PF00982.21 EGE02579.1 - 7.3e-149 496.5 0.0 1.1e-148 495.8 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGE02579.1 - 3.1e-82 275.2 0.0 5.8e-82 274.3 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_hydro_44 PF12891.7 EGE02580.1 - 0.06 13.3 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase family 44 LETM1 PF07766.13 EGE02581.1 - 5.2e-10 39.1 0.3 1.5e-05 24.5 0.2 2.4 1 1 1 2 2 2 2 LETM1-like protein N_BRCA1_IG PF16158.5 EGE02582.1 - 1.2e-30 106.2 0.0 2.6e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EGE02582.1 - 7.7e-17 60.8 37.0 6.9e-07 29.0 8.5 3.5 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EGE02582.1 - 0.25 11.7 39.1 0.053 13.8 7.8 3.9 4 0 0 4 4 4 0 C1 domain SmAKAP PF15127.6 EGE02582.1 - 0.47 11.7 0.1 0.47 11.7 0.1 2.6 3 0 0 3 3 3 0 Small membrane A-kinase anchor protein Stealth_CR3 PF17102.5 EGE02583.1 - 0.24 11.3 1.9 0.43 10.5 1.9 1.5 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 Btz PF09405.10 EGE02584.1 - 2e-23 83.0 6.6 2e-23 83.0 6.6 2.5 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 EGE02585.1 - 2.4e-26 91.4 0.1 8.7e-15 54.3 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE02585.1 - 0.0004 20.5 0.0 0.064 13.4 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGE02585.1 - 0.066 13.2 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 EGE02585.1 - 0.25 11.3 0.7 0.68 9.9 0.1 1.9 2 0 0 2 2 2 0 RL domain CCSAP PF15748.5 EGE02585.1 - 0.88 9.7 16.1 0.41 10.8 1.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Spt5_N PF11942.8 EGE02585.1 - 2.7 9.0 9.2 0.59 11.1 4.5 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ino80_Iec3 PF14612.6 EGE02586.1 - 1.8e-73 248.1 8.4 2.2e-73 247.8 8.4 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling FAD_binding_4 PF01565.23 EGE02587.1 - 1e-18 67.4 0.5 1.9e-18 66.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE02587.1 - 4.2e-10 39.6 0.2 1.2e-09 38.1 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like GFA PF04828.14 EGE02588.1 - 4.2e-20 71.9 0.8 5.7e-20 71.4 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Dynamin_N PF00350.23 EGE02590.1 - 7.1e-33 114.0 0.1 1.8e-32 112.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGE02590.1 - 1.8e-24 86.5 1.8 8.4e-23 81.0 1.8 2.4 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EGE02590.1 - 4.8e-06 26.6 0.0 2.2e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE02590.1 - 0.00095 19.6 0.6 1.5 9.2 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain Roc PF08477.13 EGE02590.1 - 0.021 15.0 0.7 0.79 10.0 0.0 3.4 4 1 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase GED PF02212.18 EGE02590.1 - 0.033 14.3 1.8 1.1 9.4 0.2 2.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_18 PF13238.6 EGE02590.1 - 0.07 13.7 0.2 8.7 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGE02590.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain YABBY PF04690.13 EGE02590.1 - 0.18 12.3 0.6 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 YABBY protein AAA_15 PF13175.6 EGE02590.1 - 0.21 11.3 7.7 0.12 12.1 0.8 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGE02590.1 - 2.4 8.6 6.1 0.6 10.6 0.9 2.6 2 1 0 2 2 2 0 AAA domain ECR1_N PF14382.6 EGE02591.1 - 1.7e-14 53.3 0.6 4.2e-14 52.1 0.6 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EGE02591.1 - 6.7e-06 26.4 0.2 1.2e-05 25.5 0.2 1.4 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EGE02591.1 - 0.49 11.0 4.2 0.67 10.6 0.1 2.8 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.18 EGE02592.1 - 6e-120 400.5 0.0 1.1e-119 399.6 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EGE02592.1 - 1.2e-39 134.4 0.9 4.7e-39 132.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EGE02592.1 - 6.6e-06 26.6 0.9 2.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGE02592.1 - 0.85 10.1 4.5 19 5.7 0.8 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain Plus-3 PF03126.18 EGE02593.1 - 1.3e-05 25.7 0.1 3.8e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 Plus-3 domain COQ7 PF03232.13 EGE02594.1 - 5.3e-68 228.2 0.4 6.5e-68 227.9 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EGE02594.1 - 0.0061 17.0 0.0 0.015 15.7 0.0 1.6 2 0 0 2 2 2 1 Rubrerythrin Crr6 PF08847.11 EGE02594.1 - 0.026 14.2 0.1 1.4 8.6 0.0 2.3 1 1 1 2 2 2 0 Chlororespiratory reduction 6 DUF4455 PF14643.6 EGE02594.1 - 0.074 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) LMWPc PF01451.21 EGE02595.1 - 6.7e-37 127.0 0.0 7.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.17 EGE02596.1 - 3.5e-73 245.0 0.0 5.6e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGE02596.1 - 7.8e-30 102.6 0.0 1.6e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGE02596.1 - 2.9e-20 72.4 3.9 9.9e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGE02596.1 - 0.0018 18.2 14.5 0.0018 18.2 14.5 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Lipase_GDSL_2 PF13472.6 EGE02597.1 - 1.3e-10 42.0 0.1 4.2e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGE02597.1 - 5.3e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TMEM234 PF10639.9 EGE02598.1 - 2e-33 114.8 2.1 2.9e-32 111.1 2.1 2.0 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EGE02598.1 - 0.0013 18.9 8.4 0.039 14.1 5.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family MFS_MOT1 PF16983.5 EGE02599.1 - 1e-60 203.0 34.6 3.2e-32 111.2 9.4 3.2 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF2755 PF10954.8 EGE02599.1 - 4.4 7.3 0.0 4.4 7.3 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2755) PhyH PF05721.13 EGE02601.1 - 1.5e-42 146.2 0.0 1.9e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.10 EGE02602.1 - 1.1e-51 174.4 0.0 2e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGE02602.1 - 2.4e-17 63.0 4.1 0.00042 21.1 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE02602.1 - 1.2e-07 31.9 0.1 0.1 12.9 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGE02602.1 - 0.00083 19.0 0.9 0.014 15.0 0.1 2.4 1 1 1 2 2 2 1 PQQ-like domain RAB3GAP2_N PF14655.6 EGE02602.1 - 0.013 14.8 0.1 4.7 6.4 0.1 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 EGE02602.1 - 0.097 11.3 0.6 3.6 6.1 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 C2 PF00168.30 EGE02603.1 - 3.8e-15 56.0 0.0 6.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.6 EGE02604.1 - 1.7e-30 106.2 0.0 3.1e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE02604.1 - 1e-13 51.7 6.7 8.6e-12 45.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EGE02604.1 - 9.4e-08 32.5 0.0 1.9e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGE02604.1 - 0.00019 21.0 0.0 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 EGE02604.1 - 0.00061 19.6 0.0 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGE02604.1 - 0.0075 16.0 0.1 0.61 9.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGE02604.1 - 0.046 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2457 PF10446.9 EGE02604.1 - 3.8 6.5 7.4 5.6 6.0 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fungal_trans PF04082.18 EGE02606.1 - 7e-12 44.9 0.3 9.7e-12 44.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02606.1 - 2.2e-10 40.5 10.5 4.4e-10 39.5 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 EGE02607.1 - 0.00043 20.4 6.8 0.00043 20.4 6.8 5.9 4 1 0 4 4 4 1 IBR domain, a half RING-finger domain IL4 PF00727.18 EGE02607.1 - 0.0045 17.2 0.0 3.3 8.0 0.1 2.8 2 0 0 2 2 2 2 Interleukin 4 OTU PF02338.19 EGE02608.1 - 2.5e-07 31.2 0.0 4.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EGE02608.1 - 0.0092 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Cyclophil_like2 PF18050.1 EGE02608.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Cyclophilin-like family UBX PF00789.20 EGE02608.1 - 0.055 13.7 0.5 0.45 10.8 0.5 2.3 1 1 0 1 1 1 0 UBX domain Bromodomain PF00439.25 EGE02609.1 - 5.7e-38 128.9 3.4 3.9e-20 71.7 0.2 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EGE02609.1 - 3.5e-17 62.4 0.8 8e-17 61.2 0.8 1.7 1 0 0 1 1 1 1 BAH domain BLOC1S3 PF15753.5 EGE02609.1 - 0.74 9.9 9.2 2 8.5 1.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Nucleo_P87 PF07267.11 EGE02609.1 - 0.81 8.5 16.2 0.026 13.4 2.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EGE02609.1 - 2.5 6.3 14.4 0.01 14.2 4.4 1.8 2 0 0 2 2 2 0 CDC45-like protein Astro_capsid_p PF12226.8 EGE02609.1 - 3 6.9 7.3 6 5.9 7.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein MRC1 PF09444.10 EGE02610.1 - 1e-41 142.8 21.3 1e-41 142.8 21.3 5.5 4 1 1 5 5 5 2 MRC1-like domain Hydrolase_like PF13242.6 EGE02612.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Plus-3 PF03126.18 EGE02612.1 - 0.088 13.3 0.0 0.45 11.1 0.0 2.1 2 0 0 2 2 2 0 Plus-3 domain MIF4G PF02854.19 EGE02613.1 - 1.8e-24 86.5 4.2 4.1e-23 82.1 3.2 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EGE02613.1 - 1.1e-17 64.0 0.5 3e-17 62.6 0.1 2.0 2 0 0 2 2 2 1 MA3 domain EST1_DNA_bind PF10373.9 EGE02613.1 - 0.00034 20.2 1.6 0.00072 19.1 1.6 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain SRP14 PF02290.15 EGE02614.1 - 9.2e-29 99.7 0.0 1.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Inp1 PF12634.7 EGE02615.1 - 4.2e-38 130.4 0.1 1e-37 129.2 0.0 1.7 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 EGE02616.1 - 5e-12 46.4 5.0 1.1e-09 38.8 5.0 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3742 PF12553.8 EGE02616.1 - 0.5 10.5 0.1 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) Sugar_tr PF00083.24 EGE02618.1 - 1.1e-42 146.5 23.6 2.1e-27 96.1 6.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EGE02618.1 - 1.4e-21 76.8 26.7 9.4e-21 74.1 21.7 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily NADH-u_ox-rdase PF10785.9 EGE02618.1 - 5.8 7.7 5.6 5.2 7.8 0.3 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Pol_alpha_B_N PF08418.10 EGE02619.1 - 0.003 17.6 2.5 0.0059 16.6 2.5 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Helo_like_N PF17111.5 EGE02619.1 - 0.089 12.1 0.3 0.46 9.8 0.1 2.0 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins MRNIP PF15749.5 EGE02619.1 - 0.84 10.4 2.6 1.3 9.7 0.1 2.3 2 0 0 2 2 2 0 MRN-interacting protein FixQ PF05545.11 EGE02621.1 - 0.086 12.8 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF3397 PF11877.8 EGE02621.1 - 4.1 7.6 18.8 0.23 11.7 1.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3397) CPP1-like PF11833.8 EGE02621.1 - 5.9 6.5 6.5 0.72 9.5 1.7 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2841 PF11001.8 EGE02622.1 - 7.7e-35 119.6 0.0 1.2e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) TNT PF14021.6 EGE02623.1 - 5.2e-30 103.8 0.0 7.7e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin FmdA_AmdA PF03069.15 EGE02624.1 - 2.8e-175 582.6 0.0 3.2e-175 582.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family TPR_1 PF00515.28 EGE02625.1 - 1.6e-05 24.5 0.5 1.6e-05 24.5 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02625.1 - 2.1e-05 24.3 1.0 2.1e-05 24.3 1.0 3.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGE02625.1 - 0.0024 18.0 2.9 0.09 12.9 0.9 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02625.1 - 0.017 15.3 0.4 0.017 15.3 0.4 3.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02625.1 - 0.03 14.9 6.3 0.03 14.9 6.3 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGE02625.1 - 0.17 11.6 4.9 4.6 7.0 0.2 3.1 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 EGE02625.1 - 0.44 11.5 6.6 0.2 12.6 1.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGE02625.1 - 4 7.8 11.0 0.66 10.3 6.2 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 EGE02626.1 - 3e-52 177.0 0.1 3.4e-52 176.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 EGE02627.1 - 4.4e-87 291.3 15.3 6.6e-87 290.8 15.3 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGE02627.1 - 2.7e-42 144.0 11.5 6.2e-42 142.8 11.5 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CLZ PF16526.5 EGE02627.1 - 0.017 15.5 2.1 0.042 14.2 0.5 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2373 PF10180.9 EGE02627.1 - 0.061 13.2 4.7 0.16 11.8 4.7 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EGE02627.1 - 0.54 10.7 8.1 0.068 13.5 2.1 2.5 2 0 0 2 2 2 0 Syntaxin-like protein zf-C2H2_aberr PF17017.5 EGE02628.1 - 0.00044 20.4 0.3 0.00065 19.9 0.3 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-C2H2 PF00096.26 EGE02628.1 - 0.0034 17.7 8.2 0.32 11.5 0.2 2.9 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE02628.1 - 0.044 14.6 5.4 0.07 14.0 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger APH PF01636.23 EGE02629.1 - 1.9e-14 54.2 0.0 4.7e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DNA_binding_1 PF01035.20 EGE02631.1 - 2.5e-24 85.2 0.0 3.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.11 EGE02631.1 - 0.0037 16.9 0.2 0.0066 16.1 0.0 1.5 2 0 0 2 2 2 1 Rubella capsid protein Sugar_tr PF00083.24 EGE02632.1 - 8.3e-89 298.5 19.6 9.6e-89 298.3 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE02632.1 - 8.7e-19 67.6 49.2 1.5e-14 53.7 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE02632.1 - 2.2 6.4 11.0 0.46 8.7 2.7 2.9 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_2 PF07992.14 EGE02633.1 - 7.9e-68 228.8 7.2 7.9e-68 228.8 7.2 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGE02633.1 - 2.3e-39 134.0 0.1 6.4e-39 132.6 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGE02633.1 - 3.7e-21 75.5 12.0 1.3e-20 73.7 1.1 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGE02633.1 - 6.5e-11 42.2 10.3 1.5e-10 41.1 0.3 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE02633.1 - 1.4e-09 38.1 4.2 2.8e-05 24.3 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGE02633.1 - 2.7e-08 33.3 13.5 3e-07 29.9 4.7 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGE02633.1 - 6.7e-08 32.1 7.0 1e-05 25.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGE02633.1 - 8.7e-07 28.4 2.5 8.7e-07 28.4 2.5 2.8 2 1 1 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGE02633.1 - 1.4e-06 27.7 5.0 0.0037 16.6 0.4 3.2 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EGE02633.1 - 3.7e-06 26.3 0.7 0.094 11.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGE02633.1 - 7.1e-06 25.0 13.3 0.0006 18.6 1.4 4.0 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 EGE02633.1 - 3.6e-05 23.5 14.1 0.046 13.3 0.9 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGE02633.1 - 4.7e-05 22.7 4.8 0.00043 19.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EGE02633.1 - 0.00031 19.9 2.4 0.017 14.2 0.1 2.6 2 1 0 2 2 2 1 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 EGE02633.1 - 0.0048 16.2 1.4 0.14 11.5 0.1 3.2 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 EGE02633.1 - 0.0087 15.3 11.2 0.2 10.8 1.3 3.5 3 1 1 4 4 4 2 FAD binding domain FMO-like PF00743.19 EGE02633.1 - 0.13 10.7 1.4 0.39 9.1 0.1 2.3 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EGE02633.1 - 0.16 12.4 2.7 1.4 9.4 0.1 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EGE02633.1 - 2 7.2 7.3 1.2 8.0 0.9 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EGE02633.1 - 9 6.1 8.4 0.43 10.5 1.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PGM_PMM_I PF02878.16 EGE02635.1 - 1.6e-31 108.9 0.0 3.1e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGE02635.1 - 4.9e-25 88.1 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGE02635.1 - 4.2e-15 55.9 0.0 7.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGE02635.1 - 2.6e-07 30.7 0.0 8e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain AdoMet_MTase PF07757.13 EGE02635.1 - 0.081 13.3 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase FA_desaturase PF00487.24 EGE02636.1 - 3.1e-24 86.2 31.3 4.8e-24 85.6 31.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGE02636.1 - 4.8e-11 42.6 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.16 EGE02637.1 - 1.1e-10 40.9 0.1 2.4e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 CUE domain MCC-bdg_PDZ PF10506.9 EGE02637.1 - 0.0099 15.9 0.0 0.041 13.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Ribosomal_S10 PF00338.22 EGE02638.1 - 9.9e-27 93.1 0.3 1.2e-26 92.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 EGE02639.1 - 7.5e-09 35.2 2.5 1.5e-08 34.3 2.5 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGE02639.1 - 6.4e-06 25.9 2.7 1.4e-05 24.9 2.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE02639.1 - 8.9e-06 25.6 6.3 1.8e-05 24.6 6.3 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EGE02639.1 - 0.049 14.3 1.1 0.11 13.2 1.1 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 EGE02639.1 - 0.096 13.2 1.3 0.22 12.0 1.3 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ELYS PF13934.6 EGE02640.1 - 8.5e-66 222.1 0.2 1.2e-65 221.6 0.2 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Peptidase_M75 PF09375.10 EGE02640.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Imelysin SMC_N PF02463.19 EGE02641.1 - 1.3e-65 221.0 38.3 6.5e-65 218.6 38.3 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGE02641.1 - 1.8e-24 86.3 0.1 1.2e-23 83.6 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGE02641.1 - 2.3e-12 47.3 0.1 4.8e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGE02641.1 - 1.9e-09 37.8 14.3 1.9e-09 37.8 14.3 3.8 2 2 1 3 3 3 1 AAA ATPase domain Tektin PF03148.14 EGE02641.1 - 0.00024 20.0 16.1 0.00024 20.0 16.1 5.4 3 2 1 5 5 5 2 Tektin family AAA_29 PF13555.6 EGE02641.1 - 0.00068 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Fib_alpha PF08702.10 EGE02641.1 - 0.0052 17.0 8.0 0.0052 17.0 8.0 6.9 2 2 2 6 6 6 2 Fibrinogen alpha/beta chain family ATG16 PF08614.11 EGE02641.1 - 0.0056 16.9 18.9 0.0056 16.9 18.9 7.6 4 2 3 7 7 7 2 Autophagy protein 16 (ATG16) RT_RNaseH PF17917.1 EGE02641.1 - 0.57 10.5 6.8 0.85 9.9 0.1 3.4 3 0 0 3 3 3 0 RNase H-like domain found in reverse transcriptase Fungal_trans PF04082.18 EGE02642.1 - 4.7e-11 42.2 0.3 1.5e-10 40.6 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02642.1 - 4.9e-08 33.0 4.8 9.3e-08 32.1 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 EGE02642.1 - 0.54 8.5 6.7 0.79 7.9 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EGE02642.1 - 9.8 6.2 13.2 23 4.9 13.2 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Suc_Fer-like PF06999.12 EGE02643.1 - 4.3e-69 232.3 0.0 5.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribonuc_L-PSP PF01042.21 EGE02644.1 - 2.7e-10 40.3 0.1 4.5e-10 39.6 0.1 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 EGE02645.1 - 8.5e-06 26.4 4.5 0.39 11.7 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec62 PF03839.16 EGE02645.1 - 0.71 9.3 7.3 1.3 8.5 7.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_pol_N PF01194.17 EGE02646.1 - 3.5e-31 107.3 1.4 4e-31 107.1 1.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EGE02646.1 - 0.029 14.6 0.6 0.049 13.9 0.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) GCIP PF13324.6 EGE02648.1 - 0.37 10.4 3.5 4.9 6.7 0.0 2.9 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting Fer4_13 PF13370.6 EGE02648.1 - 1.3 9.6 3.7 10 6.7 0.0 3.7 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I Sugar_tr PF00083.24 EGE02649.1 - 4.1e-104 349.0 28.7 1.5e-103 347.1 22.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGE02649.1 - 6.1e-21 74.7 42.8 1.6e-12 47.0 14.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 EGE02650.1 - 7.3e-35 120.3 0.0 5.5e-33 114.2 0.0 2.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE02650.1 - 1.6e-14 54.2 0.0 3.9e-14 53.0 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 EGE02650.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain MFS_1 PF07690.16 EGE02651.1 - 5.4e-36 124.2 52.7 6.7e-36 123.9 49.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2254 PF10011.9 EGE02651.1 - 0.0011 17.8 0.0 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Sarcolipin PF05366.11 EGE02651.1 - 0.058 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Sarcolipin CcmD PF04995.14 EGE02651.1 - 4.4 7.5 8.0 2 8.5 0.3 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) DNA_primase_S PF01896.19 EGE02652.1 - 1.6e-60 204.1 0.1 2.8e-60 203.4 0.1 1.4 1 0 0 1 1 1 1 DNA primase small subunit TRAP_alpha PF03896.16 EGE02652.1 - 0.46 9.7 4.0 0.75 8.9 4.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC27 PF09507.10 EGE02652.1 - 1.2 8.4 24.0 0.039 13.4 18.1 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MAM33 PF02330.16 EGE02653.1 - 1.1e-74 250.9 1.2 1.3e-74 250.7 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3567 PF12091.8 EGE02653.1 - 0.16 12.1 0.5 0.99 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3567) CobW_C PF07683.14 EGE02654.1 - 1e-21 76.6 0.0 1.3e-17 63.5 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.19 EGE02654.1 - 3e-14 53.0 3.2 3.1e-10 39.9 0.3 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Tma16 PF11176.8 EGE02655.1 - 3.3e-49 166.5 3.0 4.2e-49 166.2 3.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_N PF00752.17 EGE02656.1 - 1.3e-23 83.4 0.0 1.7e-22 79.8 0.0 2.5 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.18 EGE02656.1 - 2.5e-22 79.0 0.0 5.4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EGE02656.1 - 0.0049 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing TPR_14 PF13428.6 EGE02656.1 - 0.14 13.0 0.0 0.38 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02656.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.8 EGE02657.1 - 1.5e-58 197.9 4.3 1.5e-58 197.9 4.3 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EGE02657.1 - 2.9e-06 27.1 9.0 4.8e-06 26.3 9.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family MLTD_N PF06474.12 EGE02657.1 - 0.89 9.8 7.0 0.35 11.1 3.0 2.3 2 0 0 2 2 2 0 MltD lipid attachment motif DUF898 PF05987.13 EGE02657.1 - 7.8 5.4 11.1 0.61 9.1 5.5 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) HAD_SAK_1 PF10307.9 EGE02660.1 - 1.7e-79 266.4 0.0 5.3e-79 264.7 0.0 1.7 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DUF4719 PF15843.5 EGE02660.1 - 4.6 7.3 12.5 10 6.2 12.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) zf-RING_2 PF13639.6 EGE02661.1 - 1.1e-08 35.2 9.2 2.1e-08 34.3 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE02661.1 - 6e-06 26.0 8.7 1.1e-05 25.2 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE02661.1 - 8.2e-06 25.6 8.7 8.2e-06 25.6 8.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE02661.1 - 5.7e-05 22.9 8.3 5.7e-05 22.9 8.3 1.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE02661.1 - 0.00017 21.8 9.3 0.00017 21.8 9.3 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGE02661.1 - 0.15 11.8 7.0 0.4 10.5 7.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Drc1-Sld2 PF11719.8 EGE02662.1 - 6.6e-59 200.6 25.5 1.7e-27 97.1 2.1 3.0 2 1 1 3 3 3 3 DNA replication and checkpoint protein Tli4_N PF18443.1 EGE02662.1 - 0.26 11.7 2.7 0.4 11.1 0.5 2.2 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain 2-oxoacid_dh PF00198.23 EGE02663.1 - 4.3e-81 271.8 0.0 8e-81 270.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGE02663.1 - 8.9e-16 57.5 1.4 8.9e-16 57.5 1.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme SAGA-Tad1 PF12767.7 EGE02663.1 - 0.064 13.0 2.7 0.037 13.7 0.9 1.6 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GCV_H PF01597.19 EGE02663.1 - 0.092 12.6 0.5 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAP PF07174.11 EGE02663.1 - 1.6 8.1 13.1 2.5 7.5 13.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Presenilin PF01080.17 EGE02663.1 - 1.8 7.2 4.2 2.6 6.7 4.2 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGE02663.1 - 5.7 5.5 6.5 8.5 4.9 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_LYR PF05347.15 EGE02664.1 - 1.4e-07 31.4 0.3 2e-07 30.9 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGE02664.1 - 0.16 12.7 1.2 0.31 11.8 1.2 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Histone_H2A_C PF16211.5 EGE02665.1 - 3e-18 65.3 0.4 5.4e-18 64.4 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGE02665.1 - 3.5e-16 59.7 0.0 4.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGE02665.1 - 2.9e-05 24.3 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGE02666.1 - 1.9e-16 60.6 0.5 2.5e-16 60.2 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGE02666.1 - 0.058 13.7 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Endomucin PF07010.12 EGE02666.1 - 0.11 12.5 3.9 0.13 12.3 3.9 1.1 1 0 0 1 1 1 0 Endomucin Peptidase_C54 PF03416.19 EGE02667.1 - 8.2e-99 330.5 0.0 1.2e-98 329.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 EGE02668.1 - 8.3e-12 44.9 0.0 2.4e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EGE02668.1 - 7.4e-09 35.4 0.4 1.4e-08 34.5 0.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGE02668.1 - 0.0031 17.6 0.2 0.0031 17.6 0.2 2.3 3 0 0 3 3 3 1 G-patch domain Peptidase_S49_N PF08496.10 EGE02668.1 - 0.67 10.0 6.6 0.21 11.7 1.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DnaJ PF00226.31 EGE02669.1 - 3.3e-25 88.0 0.3 9.8e-25 86.5 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 EGE02669.1 - 2.6e-12 46.7 7.5 9.1e-09 35.4 2.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGE02669.1 - 1.4e-11 44.4 9.7 9.3e-10 38.5 6.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGE02669.1 - 6.8e-10 39.2 6.6 0.00022 21.5 1.8 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EGE02669.1 - 5.7e-07 29.7 6.1 0.012 16.0 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE02669.1 - 1.3e-06 28.7 4.5 0.016 16.0 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Actin_micro PF17003.5 EGE02669.1 - 0.00054 19.3 0.6 0.21 10.8 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family DUF3449 PF11931.8 EGE02669.1 - 0.0028 17.5 1.9 0.015 15.1 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_6 PF13912.6 EGE02669.1 - 0.0086 16.0 9.4 0.72 9.9 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger LIM PF00412.22 EGE02669.1 - 0.01 16.1 1.9 1.7 8.9 0.6 2.4 2 0 0 2 2 2 1 LIM domain zf-C2H2_3rep PF18868.1 EGE02669.1 - 0.01 16.5 2.1 1.9 9.2 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 EGE02669.1 - 0.13 12.3 0.4 24 5.0 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger DUF2256 PF10013.9 EGE02669.1 - 0.16 12.1 0.7 21 5.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 EGE02669.1 - 0.37 11.3 1.5 5.8 7.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain MRNIP PF15749.5 EGE02669.1 - 2.8 8.7 11.9 0.086 13.6 3.7 2.7 2 1 1 3 3 2 0 MRN-interacting protein Choline_kin_N PF04428.14 EGE02670.1 - 0.045 13.4 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus YccV-like PF08755.11 EGE02671.1 - 6e-30 103.7 0.3 2.6e-29 101.6 0.1 2.1 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EGE02671.1 - 8.5e-15 54.7 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EGE02671.1 - 7.6e-06 25.7 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE02671.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EGE02671.1 - 0.0035 17.8 0.1 0.0072 16.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A 23S_rRNA_IVP PF05635.11 EGE02671.1 - 0.022 15.0 0.1 0.069 13.5 0.1 1.8 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein SPX PF03105.19 EGE02672.1 - 1.7e-46 159.9 0.3 3.6e-46 158.8 0.3 1.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EGE02672.1 - 8.7e-07 28.7 9.3 1.6e-06 27.9 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE02672.1 - 5.4e-06 26.5 10.5 5.4e-06 26.5 10.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGE02672.1 - 1.4e-05 24.9 10.3 3.6e-05 23.6 10.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE02672.1 - 2.3e-05 24.2 10.8 5.7e-05 22.9 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE02672.1 - 0.00015 22.0 12.5 0.00036 20.8 12.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE02672.1 - 0.00028 20.7 12.1 0.00069 19.4 12.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE02672.1 - 0.0015 18.5 10.9 0.0041 17.1 10.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGE02672.1 - 0.0096 16.0 3.4 0.021 14.9 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGE02672.1 - 0.013 15.4 9.9 0.045 13.6 10.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGE02672.1 - 0.026 14.3 3.4 0.026 14.3 3.4 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 EGE02672.1 - 0.08 13.0 0.8 0.17 12.0 0.8 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.7 EGE02672.1 - 0.41 11.0 9.8 1.4 9.3 9.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 EGE02672.1 - 0.46 10.2 8.2 12 5.7 8.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger Peptidase_C12 PF01088.21 EGE02673.1 - 1.8e-59 201.0 0.1 2.9e-59 200.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGE02673.1 - 0.06 13.3 1.6 0.17 11.8 1.6 1.8 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases DUF1918 PF08940.11 EGE02674.1 - 0.0018 17.9 0.0 11 5.8 0.0 4.2 4 0 0 4 4 4 3 Domain of unknown function (DUF1918) I-set PF07679.16 EGE02674.1 - 0.0048 16.9 0.0 0.37 10.9 0.0 3.7 5 0 0 5 5 5 1 Immunoglobulin I-set domain Nrap_D5 PF17406.2 EGE02675.1 - 3.3e-51 173.3 0.6 6.9e-51 172.2 0.2 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EGE02675.1 - 7.8e-50 168.6 0.0 1.6e-47 161.1 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EGE02675.1 - 1.4e-41 142.2 0.4 2.6e-41 141.3 0.4 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 EGE02675.1 - 2.5e-41 141.3 0.2 4.3e-41 140.5 0.2 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EGE02675.1 - 1.3e-40 139.1 0.0 2.7e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EGE02675.1 - 1.3e-27 96.7 0.0 3.1e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Fibroin_P25 PF07294.11 EGE02675.1 - 0.065 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Fibroin P25 Spc7 PF08317.11 EGE02675.1 - 0.076 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cys_Met_Meta_PP PF01053.20 EGE02676.1 - 2.1e-31 108.8 0.0 2.8e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Mt_ATP_synt PF15704.5 EGE02676.1 - 0.0037 17.2 0.1 0.0064 16.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit MRP-L20 PF12824.7 EGE02678.1 - 3.1e-58 196.6 2.7 3.5e-58 196.4 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 EGE02678.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Neugrin 14-3-3 PF00244.20 EGE02679.1 - 0.043 13.3 0.1 0.054 13.0 0.1 1.1 1 0 0 1 1 1 0 14-3-3 protein Peptidase_M20 PF01546.28 EGE02681.1 - 3.6e-32 111.8 0.0 4.6e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGE02681.1 - 5.5e-11 42.3 0.0 8.6e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGE02681.1 - 0.025 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 CobS_N PF12556.8 EGE02681.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Cobaltochelatase CobS subunit N terminal Methyltransf_25 PF13649.6 EGE02683.1 - 3.1e-09 37.4 0.0 7.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02683.1 - 9.3e-06 25.5 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02683.1 - 0.00011 22.9 0.0 0.00026 21.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02683.1 - 0.00016 22.3 0.0 0.00036 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGE02684.1 - 1.5e-23 83.2 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE02684.1 - 5.9e-13 48.9 0.0 2.5e-12 46.9 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE02684.1 - 0.0081 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGE02684.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phageshock_PspD PF09584.10 EGE02684.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) Eno-Rase_NADH_b PF12242.8 EGE02684.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AMP-binding PF00501.28 EGE02685.1 - 1.3e-66 225.0 0.0 1.8e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGE02685.1 - 7.1e-31 107.4 0.0 1.5e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EGE02685.1 - 9.4e-09 35.5 0.9 2.2e-08 34.3 0.4 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site p450 PF00067.22 EGE02686.1 - 1.5e-66 225.1 0.0 2e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4296 PF14129.6 EGE02686.1 - 0.11 13.1 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) NmrA PF05368.13 EGE02687.1 - 6e-43 147.1 0.0 8.5e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE02687.1 - 3.9e-16 59.5 0.0 5.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGE02687.1 - 0.00094 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGE02687.1 - 0.0015 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EGE02687.1 - 0.03 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 EGE02687.1 - 0.047 14.3 0.1 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MHC_II_alpha PF00993.20 EGE02687.1 - 0.097 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain DapB_N PF01113.20 EGE02687.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.16 EGE02687.1 - 0.21 11.3 0.0 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.28 EGE02688.1 - 3.4e-69 233.5 0.0 5.5e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGE02688.1 - 5.5e-56 189.6 0.0 8e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGE02688.1 - 1e-12 48.2 0.2 2e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EGE02688.1 - 3.8e-07 29.8 0.0 1.3e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGE02688.1 - 1.5e-05 24.2 0.0 3.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EGE02688.1 - 0.094 13.7 0.0 0.25 12.4 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.18 EGE02689.1 - 2.7e-34 118.3 0.0 4e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EGE02689.1 - 0.00031 21.4 0.0 0.00058 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02689.1 - 0.0041 17.8 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE02689.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGE02690.1 - 1.4e-08 35.3 0.0 3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02690.1 - 1.1e-06 29.3 0.0 2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02690.1 - 1.8e-05 25.3 0.0 4.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02690.1 - 0.00029 20.7 0.0 0.00064 19.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02690.1 - 0.021 14.7 0.0 0.41 10.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EGE02690.1 - 0.044 13.1 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MFS_1 PF07690.16 EGE02691.1 - 5.6e-51 173.5 27.2 1.2e-44 152.7 22.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE02691.1 - 5.9e-09 34.8 10.4 1.8e-08 33.1 2.1 3.5 2 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGE02691.1 - 9.2e-09 34.6 13.3 0.00016 20.7 4.4 3.5 2 1 1 3 3 3 3 MFS_1 like family DUF2627 PF11118.8 EGE02691.1 - 5.9 7.5 6.8 1.3 9.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) UPRTase PF14681.6 EGE02692.1 - 9.7e-42 142.8 0.8 1.5e-41 142.2 0.8 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 EGE02692.1 - 8.5e-22 78.1 0.0 6.1e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE02692.1 - 8.5e-06 26.3 0.0 2.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGE02692.1 - 2e-05 24.0 0.0 4.9e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 KAP family P-loop domain HAD PF12710.7 EGE02692.1 - 6.2e-05 23.5 0.0 0.52 10.7 0.0 2.7 2 1 1 3 3 2 2 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 EGE02692.1 - 9.5e-05 22.8 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Hydrolase_3 PF08282.12 EGE02692.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase G-alpha PF00503.20 EGE02692.1 - 0.0033 16.7 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_24 PF13479.6 EGE02692.1 - 0.0038 17.0 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE02692.1 - 0.0038 17.4 0.2 0.036 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGE02692.1 - 0.0041 16.4 0.0 0.0085 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ATPase_2 PF01637.18 EGE02692.1 - 0.0045 16.9 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGE02692.1 - 0.0061 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain PRTase_2 PF15609.6 EGE02692.1 - 0.0085 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase SRP54 PF00448.22 EGE02692.1 - 0.012 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EGE02692.1 - 0.017 14.3 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Peptidase_U4 PF03419.13 EGE02692.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ABC_tran PF00005.27 EGE02692.1 - 0.021 15.4 0.0 0.047 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 EGE02692.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pribosyltran PF00156.27 EGE02692.1 - 0.029 13.9 0.4 0.14 11.7 0.4 2.0 1 1 0 1 1 1 0 Phosphoribosyl transferase domain cobW PF02492.19 EGE02692.1 - 0.033 13.8 0.1 0.12 11.9 0.1 2.0 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGE02692.1 - 0.033 14.1 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.22 EGE02692.1 - 0.037 14.1 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase S6PP PF05116.13 EGE02692.1 - 0.04 13.4 0.4 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PduV-EutP PF10662.9 EGE02692.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EGE02692.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 EGE02692.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.10 EGE02692.1 - 0.077 12.4 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EGE02692.1 - 0.082 13.1 0.1 0.31 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGE02692.1 - 0.084 12.6 0.2 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGE02692.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase PRK PF00485.18 EGE02692.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PEPCK_ATP PF01293.20 EGE02692.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_5 PF07728.14 EGE02692.1 - 0.13 12.3 0.1 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) dNK PF01712.19 EGE02692.1 - 0.13 12.1 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 EGE02692.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGE02692.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRELI PF04707.14 EGE02693.1 - 1.8e-23 83.1 0.0 1.8e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family His_Phos_1 PF00300.22 EGE02694.1 - 6.2e-39 133.7 0.1 7.8e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EGE02695.1 - 3.2e-73 246.4 0.0 4.4e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02695.1 - 8e-37 126.9 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGE02695.1 - 2.7e-18 66.5 0.1 5.8e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EGE02695.1 - 2.5e-16 59.5 0.0 6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EGE02695.1 - 2.6e-06 27.0 0.0 5.6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGE02695.1 - 0.00015 21.4 0.2 0.00039 20.1 0.2 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGE02695.1 - 0.00089 18.3 0.2 0.0021 17.0 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EGE02695.1 - 0.011 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EGE02695.1 - 0.019 14.9 1.0 0.058 13.3 0.1 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EGE02695.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGE02695.1 - 0.14 11.2 0.5 0.22 10.5 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MARVEL PF01284.23 EGE02696.1 - 1.1e-22 80.6 8.9 1.4e-22 80.3 8.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3431 PF11913.8 EGE02697.1 - 1.5e-67 227.6 0.2 1.7e-67 227.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RVT_1 PF00078.27 EGE02699.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) His_Phos_1 PF00300.22 EGE02700.1 - 3.1e-12 46.6 0.0 2e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M28 PF04389.17 EGE02701.1 - 4.5e-32 111.3 0.2 8.8e-32 110.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGE02701.1 - 0.0023 17.6 0.2 0.0049 16.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1257 PF06868.11 EGE02701.1 - 0.075 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Med28 PF11594.8 EGE02701.1 - 0.089 12.9 0.3 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 28 RRM_1 PF00076.22 EGE02702.1 - 3.6e-51 170.9 0.1 2.2e-19 69.1 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE02702.1 - 1.3e-36 124.3 0.0 4.5e-30 103.3 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGE02702.1 - 3.6e-05 23.7 0.0 0.02 14.9 0.1 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 EGE02702.1 - 0.0026 17.6 0.0 0.93 9.3 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF1866) Glyco_hydro_30C PF17189.4 EGE02702.1 - 0.0094 16.2 0.4 0.018 15.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain TPR_14 PF13428.6 EGE02702.1 - 0.13 13.1 3.5 12 7.0 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat L_HMGIC_fpl PF10242.9 EGE02702.1 - 0.14 12.3 2.5 0.58 10.3 0.6 2.6 2 1 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Band_3_cyto PF07565.13 EGE02702.1 - 1.3 8.8 5.7 3.2 7.5 5.7 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TMEM51 PF15345.6 EGE02702.1 - 1.4 8.7 8.4 3.7 7.3 8.4 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 EGE02702.1 - 3.3 7.3 20.0 0.39 10.3 13.3 2.3 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 EGE02702.1 - 3.8 6.4 11.8 1.5 7.7 8.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DEAD PF00270.29 EGE02704.1 - 4.5e-47 160.1 0.0 8.5e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE02704.1 - 6.9e-25 87.6 0.0 7.1e-24 84.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGE02704.1 - 1e-19 70.5 0.2 2.6e-19 69.2 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGE02704.1 - 0.00079 19.5 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGE02704.1 - 0.042 13.1 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Ribosomal_L22 PF00237.19 EGE02705.1 - 2e-28 98.6 0.1 3.6e-28 97.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CAP_N PF01213.19 EGE02706.1 - 0.31 10.5 5.2 0.43 10.0 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Oxysterol_BP PF01237.18 EGE02707.1 - 1.9e-46 158.6 0.2 4.1e-43 147.6 0.2 3.6 1 1 0 1 1 1 1 Oxysterol-binding protein Apt1 PF10351.9 EGE02707.1 - 0.085 11.7 3.3 0.14 11.0 3.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 EGE02707.1 - 0.96 8.8 5.1 1.9 7.8 5.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cnd1_N PF12922.7 EGE02708.1 - 9.8e-58 194.7 0.0 2.6e-57 193.3 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EGE02708.1 - 7.1e-48 162.7 6.3 4.8e-44 150.3 1.1 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGE02708.1 - 1.2e-10 40.7 5.5 0.12 12.7 0.0 7.1 6 1 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EGE02708.1 - 5.6e-10 39.5 4.7 0.00025 21.4 0.0 5.4 4 2 2 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 EGE02708.1 - 2.8e-06 26.2 7.8 0.0067 15.0 0.6 4.3 4 0 0 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 EGE02708.1 - 4.2e-06 26.9 0.7 1.3 9.3 0.0 4.8 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGE02708.1 - 0.00025 21.5 7.6 0.35 11.4 0.1 5.6 5 0 0 5 5 5 1 HEAT-like repeat Cnd3 PF12719.7 EGE02708.1 - 0.0045 16.2 3.3 0.05 12.8 1.1 3.7 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain VHS PF00790.19 EGE02708.1 - 0.13 12.1 0.4 36 4.2 0.0 3.5 3 0 0 3 3 3 0 VHS domain Pkinase PF00069.25 EGE02709.1 - 7.6e-41 140.2 0.0 2.4e-37 128.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02709.1 - 2e-14 53.5 0.0 1.5e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGE02709.1 - 0.0071 16.3 0.1 0.16 11.9 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE02709.1 - 0.026 13.9 0.0 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EGE02709.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PCMT PF01135.19 EGE02710.1 - 2.7e-61 207.0 0.0 3.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGE02710.1 - 1.3e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02710.1 - 2.2e-06 28.2 0.0 3.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02710.1 - 3.4e-05 23.7 0.0 4.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02710.1 - 0.00048 20.8 0.0 0.00074 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGE02710.1 - 0.00052 20.0 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE02710.1 - 0.005 16.4 0.0 0.0086 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EGE02710.1 - 0.0091 16.6 0.0 0.016 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGE02710.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EGE02710.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGE02710.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EGE02710.1 - 0.14 11.0 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DnaJ PF00226.31 EGE02711.1 - 1.7e-22 79.3 1.3 5e-22 77.8 1.3 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGE02711.1 - 4e-19 67.1 1.5 0.00034 20.5 0.0 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGE02711.1 - 1.8e-17 62.4 1.0 9.8e-06 25.2 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGE02711.1 - 1.5e-15 57.1 0.4 0.0014 18.7 0.0 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE02711.1 - 3.8e-13 49.1 0.5 0.087 13.7 0.1 6.9 3 3 4 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02711.1 - 6.7e-12 45.7 2.2 0.011 16.3 0.4 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGE02711.1 - 1.1e-11 44.0 0.1 0.016 15.3 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02711.1 - 8.4e-11 42.3 1.1 1.4e-05 25.6 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE02711.1 - 5.9e-09 35.5 1.7 0.042 13.5 0.0 4.5 3 1 1 4 4 4 3 TPR repeat TPR_6 PF13174.6 EGE02711.1 - 1.2e-08 35.0 6.0 4.1 8.2 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE02711.1 - 1.8e-06 27.9 2.9 0.014 15.7 0.0 6.1 7 2 0 7 7 4 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EGE02711.1 - 0.00017 20.4 0.1 0.0085 14.9 0.0 2.8 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 EGE02711.1 - 0.00045 20.5 1.2 3.3 8.1 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE02711.1 - 0.00058 20.0 6.6 5.7 7.2 0.0 5.0 4 2 2 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGE02711.1 - 0.00078 19.3 0.0 26 5.2 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGE02711.1 - 0.008 16.2 1.7 5.5 7.1 0.0 3.9 3 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) HrpB1_HrpK PF09613.10 EGE02711.1 - 0.019 14.6 0.0 8.7 6.0 0.0 3.3 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 EGE02711.1 - 0.045 14.2 1.2 0.61 10.5 0.3 2.9 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 EGE02711.1 - 0.054 13.8 0.5 8.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGE02711.1 - 0.098 12.7 2.8 8.5 6.5 0.1 4.0 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF4363 PF14276.6 EGE02711.1 - 0.12 12.5 1.3 0.7 10.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) PTS_IIA PF02255.16 EGE02711.1 - 0.16 12.1 6.8 8.2 6.6 0.2 3.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit RPT PF13446.6 EGE02711.1 - 0.26 11.2 0.9 5.7 6.9 0.0 3.4 5 0 0 5 5 4 0 A repeated domain in UCH-protein LMBR1 PF04791.16 EGE02711.1 - 0.6 8.9 2.9 1.5 7.6 2.2 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein PCRF PF03462.18 EGE02712.1 - 6.8e-49 166.4 0.1 1.6e-48 165.1 0.0 1.6 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EGE02712.1 - 5.4e-28 97.2 0.7 5.4e-28 97.2 0.7 1.9 2 0 0 2 2 2 1 RF-1 domain Abdominal-A PF12407.8 EGE02712.1 - 0.6 9.7 9.1 1.2 8.7 9.1 1.5 1 0 0 1 1 1 0 Homeobox protein Mito_carr PF00153.27 EGE02713.1 - 7.9e-54 179.6 4.0 5.7e-23 80.7 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 EGE02714.1 - 2e-42 144.9 0.2 2.9e-42 144.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE02714.1 - 3.9e-28 98.0 0.6 5e-27 94.4 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGE02714.1 - 0.0077 15.6 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SMC_N PF02463.19 EGE02715.1 - 9.9e-23 80.7 0.0 8e-22 77.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGE02715.1 - 2e-17 64.4 5.6 2e-17 64.4 5.6 5.0 2 2 3 5 5 5 2 AAA domain AAA_15 PF13175.6 EGE02715.1 - 1.6e-12 47.8 0.2 1.6e-12 47.8 0.2 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EGE02715.1 - 3.9e-06 26.9 9.1 3.6e-05 23.7 0.2 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE02715.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGE02715.1 - 0.0042 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGE02715.1 - 0.11 13.0 0.3 0.11 13.0 0.3 5.4 3 2 0 3 3 3 0 ABC transporter RsgA_GTPase PF03193.16 EGE02715.1 - 3.4 7.6 10.2 2.4 8.1 0.0 4.0 4 0 0 4 4 4 0 RsgA GTPase NUDIX PF00293.28 EGE02716.1 - 7.5e-13 48.7 0.6 1.4e-12 47.8 0.6 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGE02716.1 - 0.00014 21.8 0.2 0.0017 18.3 0.2 2.3 1 1 0 1 1 1 1 NUDIX domain SUR7 PF06687.12 EGE02718.1 - 2e-25 89.7 6.2 2.8e-25 89.2 6.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family AAA_22 PF13401.6 EGE02719.1 - 0.0062 16.8 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGE02719.1 - 0.025 15.0 0.0 0.085 13.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGE02719.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGE02719.1 - 0.15 11.4 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_18 PF00704.28 EGE02720.1 - 9.9e-19 68.2 0.8 3.6e-18 66.4 0.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 zinc_ribbon_13 PF09855.9 EGE02720.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) adh_short PF00106.25 EGE02721.1 - 4.2e-35 121.0 0.0 5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE02721.1 - 2.6e-31 109.0 0.0 3.1e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE02721.1 - 1.8e-12 47.5 0.0 2.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE02721.1 - 6.5e-06 25.8 0.1 0.00013 21.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGE02721.1 - 8.5e-05 21.8 0.0 9.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EGE02721.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ion_trans_2 PF07885.16 EGE02722.1 - 6.5e-24 83.7 24.2 5.2e-14 52.0 7.6 3.3 3 0 0 3 3 3 2 Ion channel PTR2 PF00854.21 EGE02724.1 - 1.5e-56 192.0 5.7 1.5e-56 192.0 5.7 1.6 1 1 0 1 1 1 1 POT family EBP PF05241.12 EGE02724.1 - 0.64 9.4 6.4 1.3 8.5 4.2 2.3 2 0 0 2 2 2 0 Emopamil binding protein ATPgrasp_N PF18130.1 EGE02725.1 - 1.1e-18 67.6 0.1 2.3e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EGE02725.1 - 1.9e-13 50.3 0.0 6.9e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGE02725.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGE02725.1 - 0.00074 19.6 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGE02725.1 - 0.0021 17.6 0.0 0.0059 16.1 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RTA1 PF04479.13 EGE02727.1 - 5.3e-73 245.0 8.6 8.4e-73 244.4 8.6 1.3 1 0 0 1 1 1 1 RTA1 like protein DHHC PF01529.20 EGE02727.1 - 0.54 10.4 10.9 1.1 9.4 0.6 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF3433 PF11915.8 EGE02728.1 - 4.1e-31 107.3 27.3 9.6e-22 77.3 5.9 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) RRM_1 PF00076.22 EGE02730.1 - 1.8e-10 40.5 0.0 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EGE02730.1 - 1.3e-09 37.8 3.6 2.7e-09 36.8 3.6 1.5 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 EGE02730.1 - 5.2e-09 35.3 1.1 8.5e-09 34.6 1.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EGE02730.1 - 0.00029 20.9 2.9 0.00094 19.2 2.9 1.9 1 0 0 1 1 1 1 G-patch domain BRAP2 PF07576.12 EGE02730.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 Rad50_zn_hook PF04423.14 EGE02730.1 - 0.043 13.7 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif TRAF_BIRC3_bd PF16673.5 EGE02731.1 - 0.036 13.9 1.0 0.064 13.0 1.0 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Nexin_C PF08628.12 EGE02732.1 - 0.23 12.0 2.4 0.49 11.0 2.4 1.8 1 1 0 1 1 1 0 Sorting nexin C terminal SLAC1 PF03595.17 EGE02733.1 - 1.1e-97 327.2 56.7 1.3e-97 327.0 56.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MoaE PF02391.17 EGE02734.1 - 4.5e-36 123.6 0.1 5.5e-36 123.3 0.1 1.1 1 0 0 1 1 1 1 MoaE protein Ntox25 PF15530.6 EGE02734.1 - 0.2 11.8 0.0 0.3 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 25 SCO1-SenC PF02630.14 EGE02735.1 - 2.2e-44 150.6 0.0 3.2e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EGE02735.1 - 0.0021 18.0 0.0 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGE02735.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF572 PF04502.13 EGE02736.1 - 2.1 7.9 39.8 0.27 10.8 1.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF572) Yae1_N PF09811.9 EGE02737.1 - 1.8e-10 40.3 0.2 3.2e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal MFS_1 PF07690.16 EGE02738.1 - 7.6e-22 77.7 24.7 7.6e-22 77.7 24.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily RHH_4 PF13467.6 EGE02738.1 - 0.19 11.6 0.3 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain HNH_2 PF13391.6 EGE02739.1 - 5.5e-11 42.4 0.2 1.2e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease ABC_tran PF00005.27 EGE02742.1 - 9.5e-53 178.4 0.0 4.8e-32 111.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE02742.1 - 1.8e-25 90.2 8.5 1.8e-25 90.2 8.5 2.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EGE02742.1 - 7.1e-08 32.2 3.0 0.016 14.7 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE02742.1 - 4.8e-07 29.4 0.8 0.018 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGE02742.1 - 6.2e-07 29.8 0.3 0.038 14.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain DUF87 PF01935.17 EGE02742.1 - 5.7e-06 26.6 7.5 0.00069 19.8 0.3 3.2 3 0 0 3 3 3 2 Helicase HerA, central domain RsgA_GTPase PF03193.16 EGE02742.1 - 1.1e-05 25.4 1.0 0.076 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGE02742.1 - 1.2e-05 25.8 0.1 0.13 12.6 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGE02742.1 - 7.7e-05 22.6 0.0 0.35 10.6 0.1 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGE02742.1 - 0.0001 22.4 0.2 0.28 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGE02742.1 - 0.00029 21.4 0.5 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EGE02742.1 - 0.00035 20.7 0.4 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 EGE02742.1 - 0.00047 19.7 0.2 0.16 11.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGE02742.1 - 0.00072 19.2 0.1 0.73 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EGE02742.1 - 0.00086 18.7 0.8 0.71 9.2 0.1 2.6 3 0 0 3 3 2 2 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EGE02742.1 - 0.0015 17.8 0.1 0.83 8.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 EGE02742.1 - 0.0023 17.0 1.3 1.2 8.1 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_24 PF13479.6 EGE02742.1 - 0.0047 16.7 0.4 1.3 8.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EGE02742.1 - 0.0052 17.2 1.5 35 4.8 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGE02742.1 - 0.0083 16.3 0.2 5.3 7.2 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGE02742.1 - 0.0087 16.6 0.1 7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGE02742.1 - 0.014 14.6 0.1 1 8.5 0.0 2.7 2 1 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 EGE02742.1 - 0.02 14.7 0.5 3.6 7.2 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EGE02742.1 - 0.021 14.0 0.1 1.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGE02742.1 - 0.029 13.7 0.2 1.6 8.0 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGE02742.1 - 0.043 14.2 0.1 8.5 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.19 EGE02742.1 - 0.045 13.3 1.5 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EGE02742.1 - 0.052 13.2 0.1 3.2 7.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 EGE02742.1 - 0.086 13.1 0.1 17 5.8 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SNARE PF05739.19 EGE02742.1 - 0.12 12.3 0.0 0.57 10.2 0.0 2.2 1 0 0 1 1 1 0 SNARE domain TrwB_AAD_bind PF10412.9 EGE02742.1 - 0.16 10.8 1.3 9.6 5.0 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain dNK PF01712.19 EGE02742.1 - 0.19 11.6 0.2 7 6.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 EGE02742.1 - 0.22 11.5 0.3 24 5.0 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3040 PF11239.8 EGE02742.1 - 6.6 7.1 0.0 6.6 7.1 0.0 5.1 5 1 1 6 6 4 0 Protein of unknown function (DUF3040) DUF3459 PF11941.8 EGE02743.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Neocarzinostat PF00960.18 EGE02743.1 - 0.012 15.6 0.6 0.074 13.0 0.0 2.0 1 1 0 2 2 2 0 Neocarzinostatin family C2-set PF05790.15 EGE02743.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin C2-set domain AMP-binding PF00501.28 EGE02744.1 - 5.5e-112 374.4 0.1 3.5e-67 226.9 0.0 5.2 4 2 1 5 5 5 4 AMP-binding enzyme Condensation PF00668.20 EGE02744.1 - 5e-86 289.2 0.0 5.2e-25 88.0 0.0 6.4 5 2 1 6 6 6 5 Condensation domain PP-binding PF00550.25 EGE02744.1 - 3.3e-24 85.0 0.2 1.2e-13 51.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE02744.1 - 0.00097 20.1 0.0 0.012 16.6 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Amidase PF01425.21 EGE02745.1 - 1.4e-36 126.4 0.2 2.7e-36 125.5 0.2 1.4 1 0 0 1 1 1 1 Amidase Amino_oxidase PF01593.24 EGE02746.1 - 3.7e-33 115.5 0.0 4.6e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE02746.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGE02746.1 - 0.024 13.9 0.3 0.046 13.0 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ARL2_Bind_BART PF11527.8 EGE02746.1 - 0.14 12.3 0.2 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Abhydrolase_4 PF08386.10 EGE02747.1 - 2.3e-19 69.4 0.0 6.2e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EGE02747.1 - 1.5e-12 47.7 0.0 2.2e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Beta-lactamase PF00144.24 EGE02748.1 - 2.3e-45 155.3 0.0 3.2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EGE02748.1 - 3.1e-10 40.5 0.1 6.1e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Ank_4 PF13637.6 EGE02749.1 - 9.2e-43 144.1 1.4 1.1e-08 35.4 0.0 5.6 2 1 5 7 7 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE02749.1 - 5.4e-38 129.4 0.0 2.5e-12 47.2 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE02749.1 - 4.4e-31 103.5 0.0 5.4e-06 26.4 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EGE02749.1 - 8e-31 105.1 0.0 3.5e-07 30.4 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGE02749.1 - 1.4e-27 95.3 3.5 1.5e-11 44.3 0.0 6.2 3 1 5 8 8 6 6 Ankyrin repeats (many copies) NACHT PF05729.12 EGE02749.1 - 1.5e-11 44.5 0.0 3.5e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGE02749.1 - 5e-05 23.7 0.0 0.00018 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EGE02749.1 - 0.0033 16.6 0.0 0.0081 15.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 EGE02749.1 - 0.0056 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGE02749.1 - 0.012 15.9 0.0 0.039 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGE02749.1 - 0.025 15.0 0.0 0.072 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGE02749.1 - 0.042 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGE02749.1 - 0.046 14.1 0.0 2.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGE02749.1 - 0.095 12.0 0.4 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin APH PF01636.23 EGE02750.1 - 1.9e-10 41.1 0.0 5.4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGE02750.1 - 3.8e-06 26.4 0.1 0.00028 20.3 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase Choline_kinase PF01633.20 EGE02750.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EGE02750.1 - 0.0047 15.8 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EPL1 PF10513.9 EGE02752.1 - 0.093 13.1 0.7 4.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like PI3_PI4_kinase PF00454.27 EGE02753.1 - 1e-45 156.5 0.0 7.6e-45 153.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1658 PF07871.11 EGE02753.1 - 0.019 14.9 2.2 3.1 7.9 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) EF-hand_1 PF00036.32 EGE02753.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 EF hand SNF2_N PF00176.23 EGE02754.1 - 1.3e-64 218.1 0.1 1.9e-64 217.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE02754.1 - 1.2e-11 44.9 0.0 7.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE02754.1 - 0.00013 22.0 0.0 0.00035 20.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EGE02754.1 - 0.031 14.2 1.6 0.08 12.8 1.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF896 PF05979.12 EGE02754.1 - 2.2 8.2 7.1 36 4.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Med21 PF11221.8 EGE02755.1 - 4e-54 182.8 18.1 1.2e-52 178.0 18.1 2.0 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med26_C PF15693.5 EGE02755.1 - 0.011 15.9 2.4 0.013 15.6 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Spore_III_AB PF09548.10 EGE02755.1 - 0.061 13.4 0.7 0.11 12.6 0.7 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4194 PF13835.6 EGE02755.1 - 0.087 12.6 3.0 0.12 12.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) TFIIA PF03153.13 EGE02755.1 - 0.11 12.5 8.9 0.13 12.3 8.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGE02755.1 - 0.54 9.8 7.8 0.64 9.6 7.8 1.2 1 0 0 1 1 1 0 Spt20 family NINJA_B PF16136.5 EGE02755.1 - 1.5 9.2 10.3 3.1 8.2 1.0 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal SlyX PF04102.12 EGE02755.1 - 2.3 8.9 11.0 0.24 12.1 1.1 3.3 3 0 0 3 3 3 0 SlyX DUF4527 PF15030.6 EGE02755.1 - 5.3 6.4 10.4 0.07 12.5 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Med9 PF07544.13 EGE02755.1 - 5.9 7.1 10.2 0.087 12.9 1.4 2.5 2 1 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4175 PF13779.6 EGE02755.1 - 6.1 4.6 19.2 9.5 4.0 19.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2034 PF10356.9 EGE02756.1 - 1.9e-37 128.5 0.0 4e-21 75.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EGE02756.1 - 1.5e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF3431 PF11913.8 EGE02757.1 - 5.1e-83 278.1 0.0 6.5e-83 277.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MbtH PF03621.13 EGE02757.1 - 0.13 11.8 0.1 0.3 10.5 0.1 1.6 1 0 0 1 1 1 0 MbtH-like protein Spc24 PF08286.11 EGE02758.1 - 2.5e-39 133.7 3.1 9.2e-38 128.7 0.2 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6_N PF17675.1 EGE02758.1 - 0.0032 18.0 11.4 0.0044 17.5 11.4 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region MAP65_ASE1 PF03999.12 EGE02758.1 - 0.0037 16.1 3.4 0.0039 16.0 3.4 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FlaC_arch PF05377.11 EGE02758.1 - 0.017 15.5 2.9 0.79 10.2 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 EGE02758.1 - 0.02 15.1 3.0 0.18 12.0 0.2 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Syntaxin PF00804.25 EGE02758.1 - 0.023 14.4 3.0 0.045 13.4 3.0 1.5 1 0 0 1 1 1 0 Syntaxin Spc7 PF08317.11 EGE02758.1 - 0.03 13.2 8.1 0.04 12.8 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.6 EGE02758.1 - 0.03 14.3 2.4 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 FlxA-like protein CLZ PF16526.5 EGE02758.1 - 0.072 13.5 9.1 0.2 12.0 1.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4472 PF14739.6 EGE02758.1 - 0.072 13.8 1.7 0.072 13.8 1.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4795 PF16043.5 EGE02758.1 - 0.092 12.3 4.8 0.5 9.9 4.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4337 PF14235.6 EGE02758.1 - 0.1 12.7 3.9 0.13 12.3 2.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Prefoldin_2 PF01920.20 EGE02758.1 - 0.1 12.5 6.3 0.66 10.0 1.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF5344 PF17279.2 EGE02758.1 - 0.12 13.0 2.4 4.2 8.0 0.1 2.6 3 0 0 3 3 2 0 Family of unknown function (DUF5344) Streptin-Immun PF11083.8 EGE02758.1 - 0.12 12.7 1.1 0.42 11.1 0.1 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein V_ATPase_I PF01496.19 EGE02758.1 - 0.14 10.0 1.3 0.14 10.0 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 EGE02758.1 - 0.18 10.4 1.8 0.21 10.2 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DHR10 PF18595.1 EGE02758.1 - 0.27 11.3 14.2 1.1 9.3 14.2 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain EAP30 PF04157.16 EGE02758.1 - 0.28 10.4 5.6 19 4.5 5.6 2.1 1 1 0 1 1 1 0 EAP30/Vps36 family YlqD PF11068.8 EGE02758.1 - 0.49 10.8 4.4 0.76 10.1 4.4 1.3 1 0 0 1 1 1 0 YlqD protein Phage_GPO PF05929.11 EGE02758.1 - 0.53 9.9 5.9 2.5 7.7 5.8 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Swi5 PF07061.11 EGE02758.1 - 0.62 10.2 3.9 9.4 6.4 0.4 2.4 2 0 0 2 2 2 0 Swi5 Ribosomal_L29 PF00831.23 EGE02758.1 - 0.67 10.0 6.9 2.2 8.3 0.5 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein SlyX PF04102.12 EGE02758.1 - 1 10.1 7.8 1.8 9.2 1.1 2.5 2 1 0 2 2 2 0 SlyX Csm1_N PF18504.1 EGE02758.1 - 1.1 9.7 6.8 6.8 7.1 0.9 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 EGE02758.1 - 1.2 9.8 4.4 22 5.7 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF2937 PF11157.8 EGE02758.1 - 1.3 8.7 3.8 1.2 8.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Viral_P18 PF04521.13 EGE02758.1 - 2.4 8.0 6.4 6.4 6.6 1.0 2.4 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF1690 PF07956.11 EGE02758.1 - 4.9 7.6 9.7 14 6.0 9.7 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4140 PF13600.6 EGE02758.1 - 5 7.6 9.2 12 6.4 2.9 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Hsk3 PF08227.11 EGE02758.1 - 5.4 7.5 9.4 3 8.3 0.8 2.7 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Fis1_TPR_C PF14853.6 EGE02759.1 - 5.5e-26 90.4 0.4 8.8e-26 89.7 0.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGE02759.1 - 6.6e-17 60.9 0.0 1e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGE02759.1 - 0.00099 19.1 1.6 0.0023 17.9 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE02759.1 - 2.5 8.1 6.7 0.23 11.4 2.4 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGE02760.1 - 2.2e-13 50.3 9.4 2.2e-13 50.3 9.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EGE02760.1 - 3.4e-11 42.7 8.8 1.1e-10 41.1 4.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGE02760.1 - 2.5e-09 36.8 8.6 2.5e-09 36.8 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE02760.1 - 3e-09 36.6 11.6 6.6e-08 32.3 4.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE02760.1 - 3.4e-07 30.4 8.2 3.4e-07 30.4 8.2 2.4 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGE02760.1 - 4.5e-07 29.6 18.1 7.6e-07 28.9 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE02760.1 - 4.6e-07 29.7 6.1 4.6e-07 29.7 6.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_9 PF14369.6 EGE02760.1 - 2e-06 27.9 10.4 0.00015 22.0 5.1 2.5 2 0 0 2 2 2 2 zinc-ribbon Prok-RING_4 PF14447.6 EGE02760.1 - 5.8e-06 26.1 14.6 0.00015 21.6 5.2 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGE02760.1 - 4.3e-05 23.5 3.3 4.3e-05 23.5 3.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGE02760.1 - 0.00035 20.6 2.2 0.00035 20.6 2.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 EGE02760.1 - 0.00074 19.5 7.1 0.0014 18.7 0.4 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_ribbon_17 PF17120.5 EGE02760.1 - 0.0042 16.7 6.6 0.0042 16.7 6.6 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DZR PF12773.7 EGE02760.1 - 0.04 14.0 8.3 0.068 13.2 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 EGE02760.1 - 0.061 13.5 13.4 1.7 8.8 0.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 EGE02760.1 - 0.1 12.6 2.6 0.29 11.1 0.5 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 EGE02760.1 - 0.12 12.1 14.1 0.18 11.6 4.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Spt20 PF12090.8 EGE02760.1 - 0.57 9.7 13.3 0.036 13.7 7.7 1.7 2 0 0 2 2 2 0 Spt20 family DUF1272 PF06906.11 EGE02760.1 - 0.68 10.1 9.8 2.1 8.5 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PHD PF00628.29 EGE02760.1 - 0.86 9.6 14.3 0.74 9.8 7.1 2.6 2 0 0 2 2 2 0 PHD-finger UPF0547 PF10571.9 EGE02760.1 - 2.5 8.2 9.7 4.4 7.5 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 EGE02760.1 - 2.9 8.0 13.7 0.4 10.7 0.9 2.7 2 1 0 2 2 2 0 zinc-ribbons Aminotran_5 PF00266.19 EGE02761.1 - 6.1e-19 68.2 0.0 9.7e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGE02761.1 - 0.00064 19.0 0.0 0.00092 18.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE02761.1 - 0.0014 17.3 0.0 0.0021 16.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GYF PF02213.16 EGE02762.1 - 3.1e-16 58.8 2.3 4e-16 58.4 0.4 2.3 2 0 0 2 2 2 1 GYF domain B12D PF06522.11 EGE02762.1 - 0.043 13.6 0.7 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit GYF_2 PF14237.6 EGE02762.1 - 0.15 11.9 0.3 0.44 10.4 0.3 1.9 1 0 0 1 1 1 0 GYF domain 2 Homeodomain PF00046.29 EGE02762.1 - 0.46 10.4 3.7 1.4 8.8 3.7 1.8 1 0 0 1 1 1 0 Homeodomain APH PF01636.23 EGE02769.1 - 1.6e-13 51.2 0.0 4.5e-13 49.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE02769.1 - 0.0018 17.7 0.0 0.58 9.5 0.0 2.9 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EGE02769.1 - 0.0032 16.4 0.0 0.38 9.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGE02769.1 - 0.079 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGE02769.1 - 0.14 11.8 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 RIO1 family ADH_zinc_N PF00107.26 EGE02770.1 - 2.3e-23 82.6 1.0 3.3e-23 82.1 1.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE02770.1 - 1.2e-07 32.8 0.0 3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE02770.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EGE02770.1 - 0.024 13.9 1.4 0.043 13.1 1.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EGE02770.1 - 0.034 13.6 1.2 0.096 12.1 0.7 2.1 2 1 0 2 2 2 0 short chain dehydrogenase TIG PF01833.24 EGE02772.1 - 0.015 15.4 2.1 0.019 15.0 0.4 2.2 2 0 0 2 2 2 0 IPT/TIG domain Trp_syntA PF00290.20 EGE02773.1 - 6.9e-94 313.5 0.0 1.3e-93 312.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EGE02773.1 - 6.7e-48 163.6 2.2 1.1e-47 162.9 2.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Adeno_E3_CR2 PF02439.15 EGE02774.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rubella_E2 PF05749.11 EGE02774.1 - 0.04 13.4 2.4 0.055 12.9 2.4 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF5305 PF17231.2 EGE02774.1 - 0.075 12.4 0.2 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 EGE02774.1 - 0.17 11.9 0.4 0.17 11.9 0.4 1.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif ATP-synt_ab PF00006.25 EGE02775.1 - 7.4e-68 228.4 0.0 1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGE02775.1 - 3.5e-12 46.7 0.7 7.2e-12 45.6 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_S10 PF00450.22 EGE02776.1 - 6.4e-72 243.3 0.0 1.3e-71 242.2 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase GCK PF07802.11 EGE02776.1 - 0.021 15.3 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 GCK domain Usp PF00582.26 EGE02778.1 - 7e-22 78.5 0.8 1.7e-14 54.6 0.3 2.7 2 0 0 2 2 2 2 Universal stress protein family DnaJ PF00226.31 EGE02780.1 - 8.3e-22 77.1 1.7 8.3e-22 77.1 1.7 1.9 2 0 0 2 2 2 1 DnaJ domain MetOD1 PF18546.1 EGE02780.1 - 0.52 10.3 1.5 0.5 10.3 0.1 1.6 2 0 0 2 2 2 0 Metanogen output domain 1 BEN PF10523.9 EGE02781.1 - 0.12 12.7 0.1 13 6.1 0.0 3.0 2 1 1 3 3 3 0 BEN domain MbeB_N PF04837.12 EGE02782.1 - 0.095 13.0 0.6 5.7 7.3 0.0 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pkinase PF00069.25 EGE02783.1 - 1.8e-57 194.7 0.0 4e-57 193.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02783.1 - 1.4e-32 113.0 0.1 1.4e-31 109.7 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE02783.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EGE02783.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sporozoite_P67 PF05642.11 EGE02784.1 - 0.011 13.8 0.5 0.011 13.8 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CPSF100_C PF13299.6 EGE02784.1 - 0.014 15.6 0.6 0.016 15.4 0.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 EGE02784.1 - 0.092 12.4 2.4 0.11 12.1 2.4 1.2 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.8 EGE02784.1 - 0.6 9.0 5.9 0.67 8.8 5.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 EGE02784.1 - 3.4 5.9 5.8 3.8 5.7 5.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 EGE02784.1 - 4.7 6.1 10.7 5.5 5.9 10.7 1.0 1 0 0 1 1 1 0 Paf1 F-box-like PF12937.7 EGE02787.1 - 0.0034 17.2 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE02787.1 - 0.0059 16.5 1.1 0.018 14.9 0.2 2.2 2 1 0 2 2 2 1 F-box domain LRRC37 PF15779.5 EGE02788.1 - 0.062 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat-containing protein 37 family Stc1 PF12898.7 EGE02789.1 - 2.4e-17 63.2 6.1 2.9e-17 63.0 4.7 1.8 2 0 0 2 2 2 1 Stc1 domain His_Me_b4a2 PF18275.1 EGE02789.1 - 2.2 8.4 10.8 3.9 7.6 0.1 3.7 4 1 0 4 4 4 0 His-Me finger endonuclease beta4-alpha2 domain APH PF01636.23 EGE02790.1 - 2.3e-12 47.4 0.0 2e-11 44.3 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE02790.1 - 0.078 11.8 0.0 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.7 EGE02792.1 - 0.0004 20.2 0.1 0.0011 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Abhydrolase_1 PF00561.20 EGE02793.1 - 1.2e-15 57.8 0.0 8.6e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE02793.1 - 0.0022 17.3 0.0 0.013 14.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SelP_N PF04592.14 EGE02794.1 - 3.3 7.1 12.6 6.1 6.2 12.6 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Stn1 PF10451.9 EGE02795.1 - 4.9e-13 48.6 0.1 9.6e-12 44.4 0.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 Inv-AAD PF18785.1 EGE02800.1 - 8.9e-47 158.2 0.1 1.5e-46 157.4 0.1 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EGE02800.1 - 4e-09 36.3 0.1 4.6e-08 32.9 0.0 2.4 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EGE02800.1 - 2.2e-06 27.7 0.0 3e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 EGE02800.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 SNAD4 PF18750.1 EGE02800.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Metallophos PF00149.28 EGE02801.1 - 8.4e-12 46.0 0.3 1e-11 45.7 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CW_binding_2 PF04122.12 EGE02802.1 - 0.19 12.4 0.2 0.8 10.4 0.1 1.9 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 RNase_PH PF01138.21 EGE02803.1 - 6.2e-12 46.1 0.0 1.7e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF390 PF04094.14 EGE02804.1 - 0.099 10.9 0.7 0.12 10.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Ferritin-like PF12902.7 EGE02804.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like Cytochrom_C PF00034.21 EGE02805.1 - 1.6e-11 45.2 0.1 3.6e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGE02805.1 - 1.4e-07 31.7 0.8 1.4e-07 31.7 0.8 2.2 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.14 EGE02805.1 - 0.015 15.9 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.6 EGE02805.1 - 0.074 12.8 0.1 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c-550 domain BPS1 PF05633.11 EGE02805.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related Baculo_PEP_C PF04513.12 EGE02807.1 - 0.1 12.6 5.7 0.55 10.3 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_A_bac PF01000.26 EGE02808.1 - 1.7e-30 105.6 0.0 2.7e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGE02808.1 - 2.1e-14 52.7 0.0 2.7e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NUDIX PF00293.28 EGE02809.1 - 1e-18 67.7 0.2 1.2e-18 67.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 EGE02810.1 - 1.1e-48 165.3 4.7 1.7e-48 164.6 4.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGE02810.1 - 8e-24 83.8 3.9 2.1e-23 82.5 3.9 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 EGE02810.1 - 0.035 14.3 0.2 0.035 14.3 0.2 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.15 EGE02811.1 - 8.5e-30 103.9 38.0 7.6e-29 100.8 38.0 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1418 PF07214.12 EGE02811.1 - 1 9.3 6.5 5.3 7.0 2.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) SRA1 PF07304.11 EGE02812.1 - 2.1e-12 47.1 0.0 2.1e-12 47.1 0.0 2.8 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EGE02812.1 - 8.5e-08 32.2 0.1 2e-06 27.7 0.1 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 EGE02812.1 - 0.0021 18.1 0.2 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Prp18 domain RRM_1 PF00076.22 EGE02813.1 - 7.3e-16 57.7 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE02813.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EGE02813.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif COX6B PF02297.17 EGE02815.1 - 1.3e-19 70.2 7.0 1.6e-19 69.9 7.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 EGE02815.1 - 0.044 13.9 1.1 0.11 12.6 1.2 1.7 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.26 EGE02815.1 - 0.045 13.3 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CX9C PF16860.5 EGE02815.1 - 0.049 13.7 3.9 0.07 13.2 3.1 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EGE02815.1 - 0.072 13.1 2.6 0.11 12.4 2.5 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain T2SSJ PF11612.8 EGE02815.1 - 0.22 11.7 0.8 2.7 8.2 0.8 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein J Mito_carr PF00153.27 EGE02816.1 - 3.1e-43 145.6 0.1 7.8e-16 57.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 EGE02817.1 - 2.3e-33 115.7 0.0 5.3e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGE02817.1 - 6.3e-05 23.3 0.0 0.00019 21.8 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 EGE02818.1 - 8.6e-43 145.9 2.3 1.3e-42 145.3 2.3 1.2 1 0 0 1 1 1 1 GrpE DLEU7 PF15760.5 EGE02818.1 - 0.044 13.3 0.8 0.071 12.6 0.7 1.4 1 1 0 1 1 1 0 Leukemia-associated protein 7 PEARLI-4 PF05278.12 EGE02818.1 - 0.076 12.6 2.5 0.12 12.0 2.5 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) HSCB_C PF07743.13 EGE02818.1 - 3.8 8.1 8.4 2.2 8.9 2.8 2.3 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Uds1 PF15456.6 EGE02819.1 - 1.3e-28 99.7 3.7 2.9e-28 98.7 3.7 1.6 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 EGE02819.1 - 0.014 15.4 1.3 0.036 14.0 0.3 2.2 2 0 0 2 2 2 0 Stathmin family IF2_N PF04760.15 EGE02820.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Calcipressin PF04847.12 EGE02823.1 - 2.2e-32 112.3 0.1 3.2e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Calcipressin YhdX PF17444.2 EGE02823.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized YhdX-like Pex14_N PF04695.13 EGE02824.1 - 1.1e-31 110.6 1.1 1.1e-31 110.6 1.1 2.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sigma70_ECF PF07638.11 EGE02824.1 - 0.078 12.9 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 ECF sigma factor PAPA-1 PF04795.12 EGE02825.1 - 8e-32 109.9 5.6 8e-32 109.9 5.6 3.1 3 0 0 3 3 3 1 PAPA-1-like conserved region Mus7 PF09462.10 EGE02827.1 - 1.8e-147 492.8 0.1 2.8e-147 492.2 0.1 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4050 PF13259.6 EGE02828.1 - 5.4e-57 193.1 1.4 8.2e-57 192.5 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) TPR_12 PF13424.6 EGE02829.1 - 0.0002 21.6 4.0 0.8 10.0 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02829.1 - 0.00026 21.5 2.4 0.4 11.2 2.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02829.1 - 0.054 13.6 3.6 18 5.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE02829.1 - 0.46 10.7 4.3 4.8 7.5 0.7 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 EGE02830.1 - 3.4e-17 62.7 0.0 5.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02830.1 - 5.3e-09 35.7 0.0 2.4e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGE02830.1 - 0.044 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGE02830.1 - 0.051 13.2 0.3 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EGE02830.1 - 0.083 11.6 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase AAA PF00004.29 EGE02831.1 - 3.1e-38 131.2 0.0 7.7e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE02831.1 - 2.3e-09 36.9 0.1 6.5e-09 35.5 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EGE02831.1 - 4.5e-05 23.9 0.0 0.00076 19.9 0.0 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGE02831.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE02831.1 - 0.00012 22.4 0.1 0.013 15.8 0.0 2.8 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EGE02831.1 - 0.0003 20.1 0.0 0.00063 19.0 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGE02831.1 - 0.00066 19.9 0.0 0.0025 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGE02831.1 - 0.00089 19.3 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGE02831.1 - 0.0029 17.0 0.1 0.0076 15.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGE02831.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGE02831.1 - 0.0092 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGE02831.1 - 0.012 16.1 0.0 0.068 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGE02831.1 - 0.014 15.7 0.0 0.048 14.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGE02831.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EGE02831.1 - 0.02 15.0 0.0 0.69 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EGE02831.1 - 0.038 14.4 0.2 0.18 12.2 0.1 2.3 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EGE02831.1 - 0.045 13.8 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGE02831.1 - 0.048 13.9 1.4 0.058 13.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 EGE02831.1 - 0.076 12.4 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 EGE02831.1 - 0.097 12.6 0.1 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 NACHT domain IPT PF01745.16 EGE02831.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase Rrn6 PF10214.9 EGE02832.1 - 0.059 11.9 9.1 0.065 11.7 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Suf PF05843.14 EGE02832.1 - 0.42 10.5 11.6 0.45 10.5 11.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 EGE02832.1 - 0.63 10.1 3.6 0.61 10.1 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EGE02832.1 - 2.4 8.1 38.7 3 7.7 38.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 EGE02832.1 - 2.9 7.9 12.5 3.8 7.5 12.5 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PAT1 PF09770.9 EGE02832.1 - 3.1 6.0 19.4 3 6.0 19.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 EGE02832.1 - 4.2 7.1 9.6 5.4 6.7 9.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LIM_bind PF01803.16 EGE02833.1 - 1.2e-47 162.5 0.0 1.2e-47 162.5 0.0 2.8 2 1 1 3 3 3 1 LIM-domain binding protein cobW PF02492.19 EGE02834.1 - 2.6e-33 115.1 0.0 3.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGE02834.1 - 3.8e-06 26.1 0.0 0.0052 15.8 0.0 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EGE02834.1 - 0.0057 17.2 0.0 0.0079 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGE02834.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EGE02834.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 EGE02834.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IstB_IS21 PF01695.17 EGE02834.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 EGE02834.1 - 0.15 11.6 0.1 6.2 6.3 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 EGE02834.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 EGE02834.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PRK PF00485.18 EGE02834.1 - 0.2 11.4 0.0 0.66 9.7 0.0 1.8 1 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family BING4CT PF08149.11 EGE02835.1 - 2.6e-39 132.9 1.1 1.7e-35 120.7 0.0 3.3 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EGE02835.1 - 4e-09 36.6 0.1 0.98 9.8 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE02835.1 - 4.9e-05 24.0 2.2 0.47 11.4 0.0 4.6 5 1 1 6 6 6 2 WD domain, G-beta repeat DUF4427 PF14468.6 EGE02835.1 - 0.032 14.3 0.3 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) CHASE3 PF05227.13 EGE02835.1 - 4.3 7.2 11.0 0.17 11.8 4.3 2.0 2 0 0 2 2 2 0 CHASE3 domain RIBIOP_C PF04950.12 EGE02836.1 - 1.2e-109 366.3 0.0 2e-109 365.5 0.0 1.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGE02836.1 - 1.5e-23 82.7 0.0 3e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF503 PF04456.12 EGE02836.1 - 0.16 11.8 0.8 0.3 11.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF503) HlyIII PF03006.20 EGE02837.1 - 5.1e-37 127.7 12.3 7.1e-37 127.3 12.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related ATP-synt_8 PF00895.20 EGE02837.1 - 0.27 11.7 0.3 0.27 11.7 0.3 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 DUF726 PF05277.12 EGE02838.1 - 5.2e-100 334.7 0.0 9.3e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EGE02838.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain DUF4407 PF14362.6 EGE02838.1 - 0.14 11.5 1.6 0.18 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glu-tRNAGln PF02686.15 EGE02839.1 - 8e-14 51.7 0.4 5.8e-13 48.9 0.4 2.1 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF2390 PF09523.10 EGE02839.1 - 0.046 14.0 1.0 1.1 9.6 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) SNAP PF14938.6 EGE02840.1 - 5.6e-84 281.9 21.5 7.8e-63 212.5 16.3 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGE02840.1 - 2.3e-07 31.0 10.3 0.0025 18.1 1.4 3.6 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02840.1 - 0.00026 20.9 13.7 0.57 10.4 0.1 6.6 3 1 4 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE02840.1 - 0.0045 16.9 6.2 17 5.8 0.0 5.8 2 1 1 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 EGE02840.1 - 0.0078 16.7 16.8 0.14 13.0 0.4 6.1 5 0 0 5 5 5 1 Aromatic-di-Alanine (AdAR) repeat TPR_8 PF13181.6 EGE02840.1 - 0.013 15.7 14.8 0.43 10.9 0.1 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE02840.1 - 0.022 15.4 14.4 4.1 8.2 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 EGE02840.1 - 0.033 13.8 1.1 0.048 13.3 1.1 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 DFF40 PF09230.10 EGE02840.1 - 0.061 12.9 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa PTS_IIA PF02255.16 EGE02840.1 - 0.17 12.0 2.3 2.3 8.3 0.0 2.9 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_16 PF13432.6 EGE02840.1 - 0.5 11.1 17.4 2.3 8.9 3.3 4.3 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGE02840.1 - 1.4 9.0 9.0 3.6 7.7 0.2 4.3 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EGE02840.1 - 3.5 7.6 14.1 5.4 7.0 0.3 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EGE02841.1 - 0.00065 20.2 0.3 0.0065 17.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE02841.1 - 0.0065 17.0 0.0 0.32 11.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_10 PF12846.7 EGE02841.1 - 0.045 12.7 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 EGE02841.1 - 0.048 14.0 0.0 0.22 11.9 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain ClpB_D2-small PF10431.9 EGE02841.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein NB-ARC PF00931.22 EGE02841.1 - 0.14 11.3 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 EGE02841.1 - 0.2 11.2 0.0 0.74 9.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Torus PF16131.5 EGE02841.1 - 0.22 12.3 0.4 0.41 11.4 0.4 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 EGE02841.1 - 0.64 10.1 3.3 3.9 7.7 3.3 2.3 1 1 0 1 1 1 0 Zinc finger domain Cupin_1 PF00190.22 EGE02844.1 - 4.5e-33 114.0 0.0 1.2e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGE02844.1 - 1.6e-19 69.4 0.6 1.1e-10 41.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EGE02844.1 - 3.5e-06 26.6 0.1 0.011 15.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 EGE02844.1 - 0.18 11.4 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Tudor_1_RapA PF18339.1 EGE02847.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain 1 Usher_TcfC PF17271.2 EGE02847.1 - 0.21 10.3 2.2 0.3 9.8 2.2 1.2 1 0 0 1 1 1 0 TcfC Usher-like barrel domain HTH_ParB PF17762.1 EGE02851.1 - 2.8 7.8 7.6 0.73 9.7 0.6 2.5 2 1 1 3 3 3 0 HTH domain found in ParB protein MBF1 PF08523.10 EGE02851.1 - 4.6 7.8 11.9 2.7 8.5 2.6 2.9 1 1 2 3 3 3 0 Multiprotein bridging factor 1 Lectin_C PF00059.21 EGE02852.1 - 0.00013 22.7 0.9 0.00047 20.9 0.3 2.2 2 0 0 2 2 2 1 Lectin C-type domain Pyr_redox_2 PF07992.14 EGE02853.1 - 3.1e-05 23.4 0.0 0.00039 19.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE02853.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGE02853.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TMCO5 PF14992.6 EGE02854.1 - 0.072 12.7 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family Shugoshin_N PF07558.11 EGE02854.1 - 0.082 12.8 0.5 0.16 11.9 0.5 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cnn_1N PF07989.11 EGE02854.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EGE02854.1 - 0.16 11.8 0.4 0.27 11.1 0.4 1.2 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EGE02854.1 - 0.17 12.4 1.2 0.29 11.6 1.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB AKNA PF12443.8 EGE02854.1 - 0.32 11.7 5.8 0.47 11.1 0.4 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor Carn_acyltransf PF00755.20 EGE02855.1 - 6.5e-209 695.4 0.0 7.4e-209 695.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.10 EGE02856.1 - 4.3e-46 156.8 1.7 2e-45 154.6 0.0 2.7 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EGE02856.1 - 0.00042 20.4 0.0 0.0063 16.6 0.0 2.4 2 0 0 2 2 2 1 LCCL domain Macoilin PF09726.9 EGE02856.1 - 5.1 5.5 12.1 8.5 4.8 0.1 2.4 2 0 0 2 2 2 0 Macoilin family CLN3 PF02487.17 EGE02857.1 - 4.7e-161 536.3 1.2 5.4e-161 536.1 1.2 1.0 1 0 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.13 EGE02858.1 - 3.2e-33 115.4 0.0 1.3e-22 80.7 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGE02858.1 - 0.092 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.21 EGE02859.1 - 3.9e-113 378.2 0.0 5e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGE02859.1 - 4.7e-05 22.7 0.0 0.00017 20.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.12 EGE02860.1 - 1.9e-20 73.1 4.6 1.9e-20 73.1 4.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Msap1 PF17077.5 EGE02860.1 - 0.15 11.2 1.5 0.18 11.0 1.5 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 MSA_2 PF00985.17 EGE02860.1 - 0.18 12.2 2.5 0.2 12.0 2.5 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family ORC6 PF05460.13 EGE02860.1 - 0.39 9.9 4.4 0.41 9.9 4.4 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DprA_WH PF17782.1 EGE02860.1 - 5.9 7.1 6.4 3.9 7.6 0.3 2.3 2 0 0 2 2 2 0 DprA winged helix domain HMGL-like PF00682.19 EGE02861.1 - 1.5e-44 152.5 0.0 1.8e-44 152.3 0.0 1.0 1 0 0 1 1 1 1 HMGL-like PE PF00934.20 EGE02861.1 - 0.3 11.5 1.6 0.48 10.8 0.4 2.1 2 1 0 2 2 2 0 PE family Diphthamide_syn PF01866.17 EGE02862.1 - 3.9e-119 397.6 0.0 5e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.25 EGE02863.1 - 1.4e-06 28.3 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 Bromodomain DUF465 PF04325.13 EGE02863.1 - 3.8 7.6 9.3 15 5.7 1.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF465) ATG16 PF08614.11 EGE02864.1 - 0.009 16.3 0.5 0.009 16.3 0.5 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Sugarporin_N PF11471.8 EGE02864.1 - 0.041 13.9 2.7 0.076 13.0 2.7 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension OSCP PF00213.18 EGE02865.1 - 2.2e-45 154.9 1.7 3e-45 154.4 1.7 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mob1_phocein PF03637.17 EGE02866.1 - 1.5e-72 243.1 0.1 1.9e-72 242.8 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.10 EGE02867.1 - 4.2e-135 451.1 0.0 9.1e-135 450.0 0.0 1.6 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EGE02867.1 - 2.1e-05 24.6 0.0 6.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGE02867.1 - 0.001 19.5 0.0 0.29 11.6 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Neugrin PF06413.11 EGE02868.1 - 1.5e-09 38.2 2.7 2.5e-09 37.5 2.7 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EGE02868.1 - 5.5e-08 33.2 6.6 1.2e-07 32.0 6.6 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_DeoR PF08220.12 EGE02868.1 - 0.04 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_7 PF02796.15 EGE02868.1 - 0.092 12.8 0.2 0.68 10.1 0.0 2.6 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase ICMT PF04140.14 EGE02869.1 - 3e-29 101.3 0.3 3e-29 101.3 0.3 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGE02869.1 - 3.2e-11 43.6 3.4 3.2e-11 43.6 3.4 1.9 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.12 EGE02869.1 - 1.4e-05 24.7 0.5 2.4e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) 7tm_3 PF00003.22 EGE02869.1 - 0.1 12.3 9.5 0.14 11.8 9.5 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Tmemb_170 PF10190.9 EGE02871.1 - 1.2e-23 83.4 9.3 1.4e-23 83.2 9.3 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Cwf_Cwc_15 PF04889.12 EGE02872.1 - 5.4e-88 294.9 17.2 6.2e-88 294.7 17.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EGE02872.1 - 0.02 14.8 14.4 0.029 14.2 14.4 1.5 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF3752 PF12572.8 EGE02872.1 - 0.03 14.9 14.4 0.039 14.5 14.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) SDA1 PF05285.12 EGE02872.1 - 0.31 10.4 19.7 0.36 10.2 19.7 1.1 1 0 0 1 1 1 0 SDA1 PA26 PF04636.13 EGE02872.1 - 1.5 7.7 4.1 1.8 7.4 4.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 EGE02872.1 - 1.9 6.7 15.1 2.1 6.6 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EGE02872.1 - 3.9 5.5 5.8 4.5 5.3 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EGE02872.1 - 9.3 4.9 7.7 11 4.6 7.7 1.1 1 0 0 1 1 1 0 Presenilin Med22 PF06179.12 EGE02874.1 - 7e-20 71.2 1.6 8.5e-20 70.9 1.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PrmC_N PF17827.1 EGE02874.1 - 0.02 15.4 2.1 0.14 12.7 2.1 2.1 1 1 0 1 1 1 0 PrmC N-terminal domain DHFR_1 PF00186.19 EGE02875.1 - 5.3e-18 65.2 0.0 2.6e-09 37.0 0.0 3.3 3 1 0 3 3 3 3 Dihydrofolate reductase TPALS PF18178.1 EGE02875.1 - 0.053 13.0 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Voltage_CLC PF00654.20 EGE02876.1 - 4e-90 302.6 23.9 5.7e-90 302.1 20.2 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Lipase_GDSL_2 PF13472.6 EGE02877.1 - 1.2e-22 81.2 0.0 2.5e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGE02877.1 - 2.3e-16 60.4 0.0 3.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Trimer_CC PF08954.11 EGE02878.1 - 0.44 10.2 3.0 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 Trimerisation motif Isochorismatase PF00857.20 EGE02883.1 - 2.2e-27 96.4 0.0 2.7e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.15 EGE02884.1 - 1.8e-75 253.5 0.3 1.8e-75 253.5 0.3 1.5 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EGE02884.1 - 3.3e-59 199.2 3.4 3.8e-59 199.0 2.6 1.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase QRPTase_C PF01729.19 EGE02884.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.6 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PfkB PF00294.24 EGE02884.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NMO PF03060.15 EGE02884.1 - 0.23 10.8 7.0 0.053 12.9 3.2 1.9 2 1 0 2 2 2 0 Nitronate monooxygenase eIF-5_eIF-2B PF01873.17 EGE02885.1 - 3.5e-39 133.3 0.0 5.6e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 PcfK PF14058.6 EGE02885.1 - 0.027 14.7 3.4 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 PcfK-like protein BUD22 PF09073.10 EGE02885.1 - 1.1 8.5 18.1 1.5 8.1 18.1 1.1 1 0 0 1 1 1 0 BUD22 TTRAP PF14203.6 EGE02886.1 - 0.038 14.0 0.5 0.62 10.1 0.1 3.2 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein FPN1 PF06963.12 EGE02887.1 - 8.6e-38 130.0 6.1 9.9e-38 129.8 6.1 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) GMC_oxred_N PF00732.19 EGE02888.1 - 1.4e-47 162.5 0.0 1.8e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGE02888.1 - 6.5e-32 111.0 0.0 1e-31 110.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EGE02888.1 - 0.0043 16.3 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE02888.1 - 0.0046 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGE02888.1 - 0.0081 15.2 0.4 0.014 14.5 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGE02888.1 - 0.021 13.9 1.9 0.051 12.6 1.8 1.6 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EGE02888.1 - 0.026 14.1 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE02888.1 - 0.041 13.1 0.1 0.072 12.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE02888.1 - 0.057 12.1 0.6 0.08 11.6 0.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EGE02888.1 - 0.085 11.7 0.5 0.12 11.1 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 EGE02888.1 - 0.22 10.8 2.0 0.32 10.3 2.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Catalase PF00199.19 EGE02889.1 - 3.1e-173 576.3 0.1 3.7e-173 576.0 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGE02889.1 - 0.027 14.7 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 Catalase-related immune-responsive CFEM PF05730.11 EGE02890.1 - 1.4e-07 31.5 2.1 2.1e-07 30.9 2.1 1.3 1 0 0 1 1 1 1 CFEM domain PT PF04886.12 EGE02890.1 - 0.0002 20.8 12.7 0.0057 16.2 6.4 3.0 2 0 0 2 2 2 2 PT repeat DNA_ligase_A_M PF01068.21 EGE02891.1 - 2.6e-59 200.3 2.1 1.7e-57 194.4 0.4 2.7 2 1 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGE02891.1 - 3.2e-43 148.0 0.1 7.5e-43 146.8 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGE02891.1 - 1.1e-27 96.6 0.0 4.8e-27 94.5 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 EGE02892.1 - 6.2e-52 176.3 0.4 8.5e-52 175.8 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGE02892.1 - 7.6e-36 123.0 0.0 1.5e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EGE02892.1 - 1.2e-08 34.9 0.6 7.9e-07 28.9 0.2 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain SCA7 PF08313.12 EGE02893.1 - 6.4e-31 106.0 0.8 6.4e-31 106.0 0.8 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2151 PF10221.9 EGE02893.1 - 0.12 11.0 7.5 0.16 10.6 7.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Neugrin PF06413.11 EGE02893.1 - 0.45 10.5 7.3 0.84 9.6 7.3 1.5 1 0 0 1 1 1 0 Neugrin CDC45 PF02724.14 EGE02893.1 - 1.6 6.9 7.8 2.3 6.4 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_Eps PF04627.13 EGE02893.1 - 1.6 8.8 6.7 4.5 7.3 6.7 1.8 1 0 0 1 1 1 0 Mitochondrial ATP synthase epsilon chain DUF913 PF06025.12 EGE02893.1 - 1.8 7.4 6.3 3.3 6.6 6.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2052 PF09747.9 EGE02893.1 - 5.1 7.2 10.1 6.3 6.9 8.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AIRC PF00731.20 EGE02894.1 - 3.8e-59 198.5 1.9 7.5e-59 197.6 1.9 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGE02894.1 - 6.1e-52 175.6 0.0 1.3e-51 174.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EGE02894.1 - 1.2e-18 66.6 0.0 2.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EGE02894.1 - 0.00014 21.4 0.2 0.00049 19.6 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AlaDh_PNT_C PF01262.21 EGE02894.1 - 0.00088 18.6 0.2 0.0018 17.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrpR_N PF06506.11 EGE02894.1 - 0.0017 17.9 0.6 0.016 14.8 0.1 2.4 2 0 0 2 2 2 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.13 EGE02894.1 - 0.023 14.2 0.0 0.45 10.0 0.0 2.3 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.6 EGE02894.1 - 0.15 12.5 1.0 39 4.8 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain Ank_2 PF12796.7 EGE02895.1 - 5.9e-30 103.7 3.0 1.5e-11 44.7 0.0 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE02895.1 - 1e-25 89.8 4.3 4.7e-05 23.9 0.1 6.2 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE02895.1 - 1.1e-19 70.2 5.9 1.5e-09 37.9 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGE02895.1 - 8.9e-19 67.0 5.1 3.1e-05 24.2 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EGE02895.1 - 2.9e-17 61.0 4.6 0.033 14.7 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Mac PF12464.8 EGE02896.1 - 8.5e-11 41.9 0.1 1.3e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EGE02896.1 - 2.9e-10 39.4 11.6 2.8e-09 36.3 4.6 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGE02896.1 - 9.8e-09 34.8 10.8 4.2e-08 32.8 4.1 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase RNase_P_pop3 PF08228.11 EGE02897.1 - 7.9e-05 22.8 0.0 0.00015 21.8 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 CD34_antigen PF06365.12 EGE02897.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF3517 PF12030.8 EGE02898.1 - 2.4e-90 302.9 1.1 4e-90 302.1 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EGE02898.1 - 4.7e-41 141.0 0.0 8.5e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE02898.1 - 2.5e-22 79.9 0.0 5.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase p47_phox_C PF08944.11 EGE02898.1 - 0.057 12.8 0.7 0.17 11.3 0.7 1.8 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain Peptidase_C98 PF15499.6 EGE02898.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ADD_ATRX PF17981.1 EGE02898.1 - 0.15 12.0 0.1 0.52 10.2 0.1 1.8 2 0 0 2 2 2 0 Cysteine Rich ADD domain PALP PF00291.25 EGE02899.1 - 2.1e-46 158.7 0.3 2.8e-46 158.3 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 EGE02900.1 - 2.1e-16 59.8 53.4 2.1e-16 59.8 53.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TrkH PF02386.16 EGE02901.1 - 6.9e-137 456.9 12.5 2e-134 448.8 3.9 2.0 2 0 0 2 2 2 2 Cation transport protein TFIIE_alpha PF02002.17 EGE02902.1 - 3.9e-19 68.5 0.0 8.6e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit HTH_Crp_2 PF13545.6 EGE02902.1 - 0.007 16.3 0.6 0.013 15.5 0.6 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain zinc-ribbons_6 PF07191.12 EGE02902.1 - 0.019 14.9 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EGE02902.1 - 0.042 13.5 1.1 0.98 9.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SR1P PF13790.6 EGE02902.1 - 0.18 12.0 3.6 0.24 11.5 0.3 2.3 2 0 0 2 2 2 0 SR1 protein Gin PF10764.9 EGE02902.1 - 0.23 11.4 0.6 5 7.2 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin PseudoU_synth_1 PF01416.20 EGE02903.1 - 1.5e-10 41.5 0.0 3.4e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 tRNA pseudouridine synthase ATP_bind_2 PF03668.15 EGE02903.1 - 0.053 12.8 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family Anillin PF08174.11 EGE02904.1 - 4.7e-09 36.8 0.0 1.8e-08 34.9 0.0 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 EGE02904.1 - 1.8e-07 31.6 0.0 5.7e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.8 EGE02904.1 - 2.6 8.0 4.6 10 6.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DEAD PF00270.29 EGE02905.1 - 1.2e-31 109.9 0.0 2.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE02905.1 - 9.2e-20 71.1 0.2 3.5e-17 62.7 0.1 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGE02905.1 - 5.6e-05 23.2 0.1 0.0011 19.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGE02905.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Med19 PF10278.9 EGE02906.1 - 0.046 13.7 1.2 0.046 13.7 1.2 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 SET PF00856.28 EGE02908.1 - 5.8e-09 36.5 0.0 1.5e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 SET domain HypA PF01155.19 EGE02908.1 - 0.083 12.9 0.3 0.083 12.9 0.3 2.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4519 PF15012.6 EGE02908.1 - 0.27 11.4 2.3 2.7 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Ribosomal_L14 PF00238.19 EGE02909.1 - 1.1e-47 161.1 1.5 1.2e-47 160.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Dak1_2 PF13684.6 EGE02909.1 - 0.097 11.7 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family TFIIS_C PF01096.18 EGE02910.1 - 8.4e-15 54.3 2.8 8.4e-15 54.3 2.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGE02910.1 - 3.7e-12 45.9 1.0 3.7e-12 45.9 1.0 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EGE02910.1 - 0.014 15.7 10.1 0.33 11.3 0.6 2.7 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 EGE02910.1 - 0.045 14.1 2.5 0.045 14.1 2.5 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 EGE02910.1 - 0.39 10.8 13.3 1.9 8.6 3.1 2.5 2 2 0 2 2 2 0 Double zinc ribbon Pro_3_hydrox_C PF05373.11 EGE02911.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal Rotamase PF00639.21 EGE02912.1 - 8.6e-24 84.3 0.1 1.2e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGE02912.1 - 7.8e-16 58.7 0.0 1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EGE02912.1 - 3.6e-09 36.5 0.4 3.6e-09 36.5 0.4 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EGE02912.1 - 5.5e-05 24.0 0.0 7.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EGE02912.1 - 0.029 14.1 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 WW domain Nup54 PF13874.6 EGE02914.1 - 0.0018 18.4 0.9 0.0018 18.4 0.9 2.6 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 RRM_1 PF00076.22 EGE02915.1 - 1.6e-15 56.6 0.0 2.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.19 EGE02916.1 - 9.1e-50 169.1 0.0 1.6e-40 139.0 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGE02916.1 - 1.8e-08 34.3 0.0 6.1e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EGE02916.1 - 0.0013 18.5 0.0 0.013 15.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EGE02916.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 EGE02916.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.20 EGE02918.1 - 8.2e-14 51.7 0.0 2.5e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.21 EGE02919.1 - 2.6e-30 104.8 0.0 4.5e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.28 EGE02920.1 - 7.4e-38 126.9 12.4 5.1e-06 26.1 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGE02920.1 - 2e-31 105.5 20.1 0.00056 19.8 0.0 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE02920.1 - 5.5e-30 103.4 23.3 5.8e-24 84.1 0.5 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGE02920.1 - 1.3e-23 82.4 8.3 1.2e-07 31.3 1.0 8.4 8 1 1 9 9 9 6 TPR repeat TPR_8 PF13181.6 EGE02920.1 - 1.2e-22 78.2 12.5 0.00095 19.2 0.5 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGE02920.1 - 1.2e-21 76.9 17.0 4.4e-08 33.5 0.4 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE02920.1 - 1e-18 66.4 9.5 0.0023 18.6 0.1 9.1 7 1 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGE02920.1 - 1.1e-18 67.6 10.7 8.2e-09 36.0 0.4 8.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE02920.1 - 3.8e-14 52.7 18.9 0.0029 17.9 0.2 8.3 6 3 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGE02920.1 - 2.8e-11 43.0 11.6 0.011 16.1 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE02920.1 - 7.9e-06 25.6 12.2 2.6 8.2 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE02920.1 - 3e-05 24.1 0.9 0.18 12.0 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE02920.1 - 0.00012 22.5 16.5 2.2 9.1 0.1 7.9 10 0 0 10 10 9 1 Tetratricopeptide repeat ChAPs PF09295.10 EGE02920.1 - 0.0051 15.9 0.1 0.29 10.1 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 EGE02920.1 - 0.041 13.2 2.1 2.3 7.5 0.0 3.6 3 1 1 4 4 4 0 MalT-like TPR region PPTA PF01239.22 EGE02920.1 - 0.049 13.4 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TPR_21 PF09976.9 EGE02920.1 - 1.6 8.4 7.2 1.8 8.2 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain NAM-associated PF14303.6 EGE02920.1 - 8.1 7.1 12.1 0.87 10.3 2.4 2.6 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TPR_10 PF13374.6 EGE02920.1 - 9.8 6.2 7.1 16 5.6 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 EGE02921.1 - 5.8e-54 182.4 0.0 6.4e-54 182.2 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PET10 PF17316.2 EGE02922.1 - 1.3 8.5 7.4 6.6 6.2 3.1 2.5 1 1 1 2 2 2 0 Petite colonies protein 10 YtxH PF12732.7 EGE02922.1 - 2 9.0 3.9 27 5.4 0.1 3.9 4 1 0 4 4 4 0 YtxH-like protein Uso1_p115_C PF04871.13 EGE02922.1 - 4 7.8 6.3 1 9.8 0.3 2.7 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RINGv PF12906.7 EGE02923.1 - 5.4e-16 58.4 10.1 9.4e-16 57.7 10.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EGE02923.1 - 0.0037 17.5 8.8 0.0066 16.8 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGE02923.1 - 0.41 10.7 3.6 0.92 9.6 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 EGE02923.1 - 0.95 9.6 3.7 2 8.6 3.7 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 EGE02923.1 - 1.4 8.8 6.6 2.3 8.1 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGE02923.1 - 3.4 7.6 5.6 6.7 6.7 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RR_TM4-6 PF06459.12 EGE02923.1 - 3.6 7.4 6.7 8.4 6.1 6.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FANCL_C PF11793.8 EGE02923.1 - 4.2 7.6 6.7 9.1 6.5 6.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Merozoite_SPAM PF07133.11 EGE02923.1 - 6.4 6.7 19.4 13 5.7 19.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HeLo PF14479.6 EGE02924.1 - 4.9e-05 23.3 0.3 0.0028 17.5 0.3 2.4 1 1 0 1 1 1 1 Prion-inhibition and propagation Trypsin_2 PF13365.6 EGE02924.1 - 0.14 13.0 0.1 0.31 11.9 0.1 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain ACC_central PF08326.12 EGE02925.1 - 3.6e-283 941.3 0.0 4.4e-283 941.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGE02925.1 - 2.3e-190 633.4 0.0 4.3e-190 632.5 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGE02925.1 - 7.2e-54 182.5 0.0 1.4e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGE02925.1 - 1.7e-28 99.3 0.1 3.5e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGE02925.1 - 8.7e-23 80.5 0.0 9.8e-20 70.7 0.0 2.9 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGE02925.1 - 2.4e-15 56.1 0.2 6.8e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGE02925.1 - 8e-05 22.3 0.0 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGE02925.1 - 0.00017 21.6 0.0 0.00044 20.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Antiterm PF03589.13 EGE02925.1 - 0.059 13.7 0.0 0.82 10.0 0.0 2.7 2 0 0 2 2 2 0 Antitermination protein ATPgrasp_Ter PF15632.6 EGE02925.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 EGE02926.1 - 2.9e-57 194.0 11.8 2.9e-57 194.0 11.8 4.7 3 1 0 4 4 4 1 NUDE protein, C-terminal conserved region DUF16 PF01519.16 EGE02926.1 - 0.012 16.1 5.2 0.012 16.1 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 CLZ PF16526.5 EGE02926.1 - 0.014 15.7 3.3 0.014 15.7 3.3 3.4 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1729 PF08354.10 EGE02926.1 - 0.042 12.8 0.5 0.062 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) PSII_Pbs27 PF13326.6 EGE02926.1 - 0.11 12.9 2.8 0.25 11.6 2.8 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 ZapB PF06005.12 EGE02926.1 - 0.36 11.3 33.4 0.24 11.8 8.0 4.9 2 1 2 4 4 4 0 Cell division protein ZapB ADIP PF11559.8 EGE02926.1 - 2.2 8.4 26.0 5.5 7.1 4.8 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Chibby PF14645.6 EGE02926.1 - 8.7 6.8 12.9 6.8 7.1 4.1 3.1 1 1 0 2 2 2 0 Chibby family GAS PF13851.6 EGE02926.1 - 8.7 5.6 27.7 3.9 6.8 13.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Hexokinase_1 PF00349.21 EGE02927.1 - 3.2e-48 164.3 0.0 4.7e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGE02927.1 - 2.8e-36 125.2 0.0 4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Isochorismatase PF00857.20 EGE02928.1 - 2e-37 129.0 0.0 1.7e-36 126.0 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 EGE02928.1 - 7.3e-06 26.6 0.0 1.8e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 EGE02928.1 - 0.037 14.4 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.13 EGE02929.1 - 1.8e-40 138.1 0.0 2.3e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGE02929.1 - 0.003 17.5 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 1 Sybindin-like family Herpes_capsid PF06112.11 EGE02929.1 - 0.0091 16.1 2.8 0.012 15.7 2.8 1.3 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein NLBH PF05211.12 EGE02929.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) DUF2040 PF09745.9 EGE02930.1 - 5.1e-39 133.1 15.5 5.1e-39 133.1 15.5 3.8 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Adhesin_P1_N PF18652.1 EGE02930.1 - 4.9 7.2 18.2 13 5.9 4.9 3.3 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Zip PF02535.22 EGE02931.1 - 4.6e-22 78.7 9.3 1.1e-21 77.4 9.1 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.23 EGE02932.1 - 7.5e-65 218.9 0.0 9.1e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease BTB PF00651.31 EGE02933.1 - 0.0084 16.3 0.1 0.2 11.9 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain SWIRM-assoc_2 PF16496.5 EGE02933.1 - 0.13 11.1 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Sec7 PF01369.20 EGE02934.1 - 2.6e-30 105.5 0.1 4.1e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EGE02934.1 - 2.4e-06 27.9 0.0 5.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGE02934.1 - 1.2e-05 25.8 0.0 3.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 PH domain RNA_pol_3_Rpc31 PF11705.8 EGE02934.1 - 1.8 8.7 5.2 0.38 11.0 1.0 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_UBOX PF13445.6 EGE02935.1 - 3.2e-06 27.1 7.7 1.2e-05 25.2 1.2 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGE02935.1 - 5.3e-05 23.0 9.8 0.00021 21.1 1.8 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 EGE02935.1 - 9.4e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EGE02935.1 - 0.00015 21.7 4.8 0.00015 21.7 4.8 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGE02935.1 - 0.00015 22.0 11.0 0.0087 16.4 5.0 3.1 2 1 1 3 3 3 2 Ring finger domain Atg14 PF10186.9 EGE02935.1 - 0.00035 19.8 10.3 0.00035 19.8 10.3 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Rtf2 PF04641.12 EGE02935.1 - 0.00045 19.7 2.2 0.00045 19.7 2.2 3.3 2 1 1 3 3 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EGE02935.1 - 0.0011 18.8 13.1 0.0017 18.2 2.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE02935.1 - 0.0029 17.4 8.5 0.0037 17.1 1.0 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 EGE02935.1 - 0.0034 17.2 0.7 0.0093 15.8 0.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGE02935.1 - 0.0038 17.3 13.6 0.021 15.0 5.9 3.7 2 2 1 3 3 3 1 FYVE zinc finger DUF1195 PF06708.11 EGE02935.1 - 0.03 14.1 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Prok-RING_4 PF14447.6 EGE02935.1 - 0.077 12.9 14.0 0.039 13.8 5.6 3.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-FLZ PF04570.14 EGE02935.1 - 0.39 10.2 3.3 4 7.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of the FCS-type, C2-C2 Siva PF05458.12 EGE02935.1 - 0.46 10.1 5.9 0.13 11.9 1.2 2.1 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-C3HC4_4 PF15227.6 EGE02935.1 - 0.68 10.1 13.4 0.44 10.8 6.1 3.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING IBR PF01485.21 EGE02935.1 - 2.1 8.6 13.0 1.4 9.2 2.3 3.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 EGE02935.1 - 9.2 6.0 10.3 4.7 6.9 0.7 2.7 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type SET PF00856.28 EGE02936.1 - 1.6e-15 57.9 0.4 2.3e-14 54.1 0.4 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EGE02936.1 - 0.018 15.7 0.0 11 6.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain Peptidase_M14 PF00246.24 EGE02937.1 - 7.3e-73 245.9 0.0 9.9e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGE02937.1 - 0.079 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide NicO PF03824.16 EGE02938.1 - 4e-55 187.2 24.9 5.1e-53 180.2 8.0 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein Peptidase_S8 PF00082.22 EGE02939.1 - 2.8e-34 118.8 12.6 5.2e-34 117.9 12.6 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE02939.1 - 9.7e-18 64.6 0.2 1.6e-17 63.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DNA_pol_B_thumb PF14791.6 EGE02941.1 - 2.7e-22 78.7 0.5 1.5e-21 76.4 0.2 2.4 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGE02941.1 - 3.8e-18 65.0 0.8 7.7e-18 64.1 0.8 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EGE02941.1 - 4.1e-18 65.6 0.0 3.9e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase beta palm HHH_8 PF14716.6 EGE02941.1 - 7.8e-10 39.0 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EGE02941.1 - 0.035 14.7 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain PhoLip_ATPase_C PF16212.5 EGE02942.1 - 8.9e-83 277.9 18.3 8.9e-83 277.9 18.3 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGE02942.1 - 1.1e-26 92.2 8.1 4.2e-26 90.4 8.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGE02942.1 - 1e-12 47.9 0.0 1.8e-11 44.0 0.0 2.8 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE02942.1 - 2.4e-12 47.6 0.4 1.1e-07 32.4 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGE02942.1 - 2.9e-07 30.2 0.0 8.4e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGE02942.1 - 0.0018 18.0 0.3 0.01 15.6 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GP38 PF05268.11 EGE02942.1 - 0.72 9.4 5.6 1.6 8.3 5.6 1.5 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 RNase_PH PF01138.21 EGE02943.1 - 7.1e-19 68.6 0.0 1.5e-18 67.6 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGE02943.1 - 2.3e-08 33.9 0.2 8.4e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 WD40 PF00400.32 EGE02944.1 - 2.1e-32 110.7 31.0 1.3e-06 29.0 1.7 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE02944.1 - 1.5e-18 66.9 0.1 0.00013 22.2 0.0 5.2 3 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGE02944.1 - 0.059 11.7 0.0 0.18 10.1 0.0 1.7 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz HTH_32 PF13565.6 EGE02945.1 - 2.4e-09 37.6 0.4 1.3e-07 32.1 0.0 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EGE02945.1 - 2.7e-07 30.7 0.6 5.9e-07 29.6 0.2 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 EGE02945.1 - 3.4e-07 29.9 0.1 0.00065 19.4 0.0 2.3 2 0 0 2 2 2 2 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EGE02945.1 - 8.2e-05 22.2 0.5 0.0063 16.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_29 PF13551.6 EGE02945.1 - 0.00021 21.2 0.5 0.036 14.1 0.2 2.4 2 0 0 2 2 2 1 Winged helix-turn helix HTH_WhiA PF02650.14 EGE02945.1 - 0.00055 20.2 0.1 0.0046 17.3 0.1 2.1 2 0 0 2 2 2 1 WhiA C-terminal HTH domain HTH_24 PF13412.6 EGE02945.1 - 0.00057 19.4 0.5 1.3 8.7 0.1 2.9 2 1 0 2 2 2 2 Winged helix-turn-helix DNA-binding HTH_38 PF13936.6 EGE02945.1 - 0.0016 18.2 1.8 0.25 11.2 0.1 2.6 2 1 0 2 2 2 2 Helix-turn-helix domain HTH_20 PF12840.7 EGE02945.1 - 0.0023 17.9 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_IclR PF09339.10 EGE02945.1 - 0.013 15.2 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Sigma70_r4 PF04545.16 EGE02945.1 - 0.029 13.9 0.0 0.15 11.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.15 EGE02945.1 - 0.04 14.0 4.8 0.25 11.4 2.4 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 EGE02945.1 - 0.042 14.0 0.3 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.19 EGE02945.1 - 0.062 13.2 0.1 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 EGE02945.1 - 0.084 12.7 0.1 5.8 6.8 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MBOAT PF03062.19 EGE02947.1 - 1.4e-24 87.1 16.2 2.9e-24 86.1 16.2 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGE02947.1 - 0.007 16.6 2.6 0.02 15.2 2.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2530 PF10745.9 EGE02947.1 - 1.9 8.8 8.7 2.1 8.6 0.0 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF2530) MAPEG PF01124.18 EGE02948.1 - 3e-24 85.4 3.6 3.6e-24 85.1 3.6 1.1 1 0 0 1 1 1 1 MAPEG family OMPdecase PF00215.24 EGE02949.1 - 2.1e-75 253.2 0.0 2.4e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Aminotran_1_2 PF00155.21 EGE02951.1 - 4.1e-71 240.0 0.0 4.9e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4246 PF14033.6 EGE02952.1 - 5.8e-177 589.4 0.1 7.4e-177 589.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EGE02952.1 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DJ-1_PfpI PF01965.24 EGE02953.1 - 4.8e-21 75.3 0.0 6.3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGE02953.1 - 0.0057 16.4 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I IMS PF00817.20 EGE02954.1 - 5.5e-40 136.8 0.0 1.4e-39 135.5 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EGE02954.1 - 2.1e-23 82.5 0.0 4.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EGE02954.1 - 4.1e-14 53.3 0.0 9.2e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EGE02954.1 - 1.9e-13 49.3 12.9 1.3e-09 37.2 2.8 3.9 3 0 0 3 3 3 2 Ubiquitin binding region BRCT_2 PF16589.5 EGE02954.1 - 5.2e-10 39.6 0.0 2e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGE02954.1 - 2.5e-06 27.8 0.0 7.8e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGE02954.1 - 3e-06 27.4 0.0 7.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 EGE02954.1 - 0.00044 20.6 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EGE02954.1 - 0.028 14.7 0.1 0.17 12.3 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif PTCB-BRCT PF12738.7 EGE02954.1 - 0.034 14.1 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF1805 PF08827.11 EGE02954.1 - 0.07 13.5 0.0 0.29 11.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.28 EGE02955.1 - 1.3e-30 105.5 0.1 5.7e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EGE02955.1 - 5.3e-30 104.1 2.0 5.3e-30 104.1 2.0 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain Utp14 PF04615.13 EGE02955.1 - 5.2 5.5 44.8 9.5 4.6 44.8 1.6 1 1 0 1 1 1 0 Utp14 protein Pkinase PF00069.25 EGE02956.1 - 1.3e-45 155.8 0.7 2.3e-25 89.5 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGE02956.1 - 2.2e-20 73.0 0.0 2e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGE02956.1 - 0.018 15.0 0.1 0.055 13.4 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGE02956.1 - 0.026 13.5 0.3 0.049 12.6 0.3 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF3591 PF12157.8 EGE02957.1 - 4.9e-186 618.7 0.5 6.8e-186 618.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EGE02957.1 - 0.0049 16.9 0.7 0.0087 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EGE02957.1 - 0.017 15.0 3.4 0.039 13.8 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_15 PF09445.10 EGE02958.1 - 9.5e-50 168.4 0.0 1.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EGE02958.1 - 1.1e-08 35.1 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EGE02958.1 - 2.2e-08 34.0 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EGE02958.1 - 2.5e-07 30.6 0.0 3.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EGE02958.1 - 0.00032 20.5 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGE02958.1 - 0.0005 20.0 0.0 0.00075 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EGE02958.1 - 0.0007 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 EGE02958.1 - 0.0019 18.8 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 EGE02958.1 - 0.0039 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_3 PF01596.17 EGE02958.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.14 EGE02958.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EGE02958.1 - 0.055 14.1 0.0 0.097 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGE02958.1 - 0.062 12.7 0.0 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 EGE02958.1 - 0.079 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase GRASP55_65 PF04495.14 EGE02959.1 - 5.3e-42 143.4 0.0 5.4e-40 136.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.9 EGE02960.1 - 9.9e-42 142.0 0.1 2.7e-41 140.6 0.1 1.7 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.20 EGE02961.1 - 3.5e-121 405.6 0.0 4.9e-121 405.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Methyltransf_23 PF13489.6 EGE02962.1 - 4.5e-27 94.9 0.0 6.2e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02962.1 - 4.1e-10 40.2 0.0 9.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02962.1 - 2.1e-09 37.4 0.0 3.4e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE02962.1 - 6e-07 30.1 0.0 1.9e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE02962.1 - 1.2e-06 29.0 0.0 2.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE02962.1 - 0.00067 19.2 0.8 0.002 17.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EGE02962.1 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGE02962.1 - 0.031 13.6 0.0 0.22 10.8 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGE02962.1 - 0.039 13.3 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGE02962.1 - 0.11 12.0 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EGE02962.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Proteasome PF00227.26 EGE02965.1 - 1.2e-47 161.9 0.1 1.4e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EGE02965.1 - 7.4e-15 54.1 0.1 7.4e-15 54.1 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 EGE02966.1 - 4e-11 42.8 0.0 6.2e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EGE02966.1 - 2.1e-06 27.9 0.0 0.00097 19.4 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 EGE02966.1 - 0.018 15.5 0.1 0.046 14.3 0.1 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Fungal_trans PF04082.18 EGE02967.1 - 3.3e-13 49.3 0.2 5.9e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE02967.1 - 2e-07 31.0 9.4 3.6e-07 30.2 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-Y PF00387.19 EGE02968.1 - 0.091 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Acetyltransf_7 PF13508.7 EGE02969.1 - 8e-08 32.6 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE02969.1 - 8.7e-08 32.4 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE02969.1 - 7.6e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE02969.1 - 0.00014 21.9 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE02969.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein GAD-like PF08887.11 EGE02969.1 - 0.051 13.4 0.1 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 GAD-like domain MOZ_SAS PF01853.18 EGE02969.1 - 0.14 11.8 0.0 0.78 9.4 0.0 1.9 2 0 0 2 2 2 0 MOZ/SAS family Raptor_N PF14538.6 EGE02970.1 - 0.0052 16.7 0.1 0.021 14.8 0.0 2.0 2 1 1 3 3 3 1 Raptor N-terminal CASPase like domain AA_permease_2 PF13520.6 EGE02973.1 - 1.5e-53 182.1 41.2 1.9e-53 181.8 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE02973.1 - 3.4e-26 91.9 32.6 4.7e-26 91.4 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease KH_1 PF00013.29 EGE02974.1 - 1.8e-43 146.2 4.0 1e-17 63.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGE02974.1 - 1.8e-11 43.7 2.0 0.011 15.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGE02974.1 - 1.2e-05 25.1 0.3 0.78 9.7 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 EGE02974.1 - 0.00012 22.0 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 1 KH-like RNA-binding domain KH_5 PF13184.6 EGE02974.1 - 0.00039 20.5 7.9 0.21 11.7 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Pol_alpha_B_N PF08418.10 EGE02974.1 - 0.018 15.0 0.6 0.029 14.3 0.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CENP-K PF11802.8 EGE02975.1 - 0.0032 17.1 5.5 2.6 7.6 5.0 2.7 2 1 0 2 2 2 2 Centromere-associated protein K Sec34 PF04136.15 EGE02975.1 - 0.065 13.1 0.4 9.4 6.1 0.0 3.2 3 0 0 3 3 3 0 Sec34-like family Fib_alpha PF08702.10 EGE02975.1 - 0.065 13.4 6.2 0.57 10.4 0.3 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sec20 PF03908.13 EGE02975.1 - 0.14 12.1 1.3 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 Sec20 Syntaxin-6_N PF09177.11 EGE02975.1 - 0.38 11.3 14.4 4 8.1 1.7 3.8 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EGE02975.1 - 0.6 8.9 14.6 0.2 10.5 6.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 EGE02975.1 - 3.5 8.1 10.1 4.4 7.7 0.1 3.2 3 1 0 3 3 3 0 Syntaxin-like protein ISG65-75 PF11727.8 EGE02975.1 - 6.8 5.8 12.0 0.81 8.9 1.4 2.3 2 0 0 2 2 2 0 Invariant surface glycoprotein Exonuc_VII_L PF02601.15 EGE02975.1 - 8.2 5.9 14.0 2.8e+02 0.8 13.7 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Abhydrolase_1 PF00561.20 EGE02976.1 - 7.4e-14 52.0 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE02976.1 - 5.4e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE02976.1 - 0.0033 18.1 0.0 0.0069 17.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGE02976.1 - 0.0061 16.2 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Methyltransf_11 PF08241.12 EGE02977.1 - 5.1e-16 59.1 0.0 9.5e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE02977.1 - 5e-15 56.0 0.0 8.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE02977.1 - 7e-11 41.9 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGE02977.1 - 2.5e-10 40.9 0.0 3.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE02977.1 - 5.7e-10 39.2 0.0 7.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE02977.1 - 6.6e-08 32.6 0.0 8.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE02977.1 - 0.0032 17.0 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGE02977.1 - 0.22 11.5 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_2 PF12680.7 EGE02978.1 - 6.4e-05 23.5 0.0 0.00019 22.0 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain AMP-binding PF00501.28 EGE02979.1 - 1.6e-147 491.5 0.0 2.4e-73 247.2 0.2 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGE02979.1 - 3e-76 257.0 0.0 1.6e-40 139.2 0.0 2.9 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EGE02979.1 - 4.6e-23 81.4 0.2 3.7e-12 46.4 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE02979.1 - 0.0096 16.9 0.0 0.91 10.6 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF5126 PF17166.4 EGE02979.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) NAD_binding_1 PF00175.21 EGE02981.1 - 2e-26 92.7 0.0 8.3e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGE02981.1 - 2.3e-24 85.6 0.0 4.4e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Mo-co_dimer PF03404.16 EGE02981.1 - 9.8e-18 64.5 0.4 2e-17 63.5 0.4 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EGE02981.1 - 7.3e-15 54.9 0.0 2.1e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oxidored_molyb PF00174.19 EGE02981.1 - 6.1e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_6 PF08030.12 EGE02981.1 - 0.0016 18.5 0.1 0.12 12.5 0.1 2.6 1 1 0 2 2 2 1 Ferric reductase NAD binding domain CAP59_mtransfer PF11735.8 EGE02982.1 - 3.6e-84 282.2 0.0 4.8e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_S64 PF08192.11 EGE02983.1 - 0.15 10.5 0.1 0.34 9.3 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S64 DUF346 PF03984.13 EGE02984.1 - 4.5e-57 189.5 62.5 3.9e-10 39.3 0.4 7.3 7 0 0 7 7 7 7 Repeat of unknown function (DUF346) Ntox14 PF15522.6 EGE02984.1 - 9.2e-06 25.2 0.0 11 5.4 0.0 6.3 7 0 0 7 7 7 1 Novel toxin 14 DUF2510 PF10708.9 EGE02984.1 - 0.026 14.3 45.8 0.33 10.8 2.9 6.3 6 0 0 6 6 6 0 Protein of unknown function (DUF2510) DUF1724 PF08350.10 EGE02984.1 - 0.039 14.1 6.2 4 7.6 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1724) GAIN_A PF18619.1 EGE02985.1 - 0.04 14.1 0.3 0.082 13.1 0.3 1.4 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Death PF00531.22 EGE02985.1 - 0.077 13.2 0.0 13 6.0 0.0 2.2 1 1 1 2 2 2 0 Death domain SNARE_assoc PF09335.11 EGE02986.1 - 1.3e-11 45.0 5.1 1.3e-11 45.0 5.1 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Amino_oxidase PF01593.24 EGE02987.1 - 5.1e-84 283.1 0.1 8.8e-83 279.1 0.1 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EGE02987.1 - 8.3e-14 51.7 0.1 2.6e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EGE02987.1 - 2.8e-07 30.6 0.1 5.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EGE02987.1 - 0.00014 22.2 5.5 0.00014 22.2 2.3 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 EGE02987.1 - 0.0023 17.6 0.1 0.0052 16.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE02987.1 - 0.0068 15.7 0.1 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE02988.1 - 1.2e-49 169.1 0.7 1.5e-49 168.9 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE02988.1 - 3.4e-17 62.6 0.2 1.7e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE02988.1 - 2.5e-16 60.0 0.2 1.2e-13 51.4 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE02988.1 - 2.6e-05 23.6 0.6 6.5e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EGE02988.1 - 7.9e-05 23.1 0.0 0.022 15.2 0.0 2.6 1 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EGE02988.1 - 0.00016 21.8 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGE02988.1 - 0.0071 15.5 0.1 0.65 9.1 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EGE02988.1 - 0.013 14.8 0.4 2.2 7.5 0.0 2.5 2 1 0 2 2 2 0 FAD binding domain DAO PF01266.24 EGE02988.1 - 0.031 13.9 3.5 0.88 9.1 0.1 3.4 2 2 1 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGE02988.1 - 0.086 12.2 0.6 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGE02988.1 - 0.094 12.8 0.1 8.5 6.4 0.0 2.9 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EGE02988.1 - 0.13 11.3 8.0 2.6 7.0 0.3 3.9 3 1 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGE02988.1 - 0.16 11.0 5.1 0.38 9.8 0.3 2.9 2 2 1 3 3 3 0 FAD binding domain APH PF01636.23 EGE02991.1 - 2.8e-13 50.3 0.0 4.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE02991.1 - 3.3e-10 39.9 0.0 7.8e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGE02991.1 - 0.0069 15.8 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Sulfotransfer_4 PF17784.1 EGE02992.1 - 4.3e-64 216.3 0.3 5.3e-64 216.0 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DUF2116 PF09889.9 EGE02992.1 - 0.0077 16.2 0.8 0.014 15.4 0.8 1.4 1 0 0 1 1 1 1 Uncharacterized protein containing a Zn-ribbon (DUF2116) Sulfotransfer_3 PF13469.6 EGE02992.1 - 0.21 12.0 3.1 2.1 8.7 3.1 2.4 1 1 0 1 1 1 0 Sulfotransferase family RWD PF05773.22 EGE02994.1 - 0.0048 17.2 0.8 0.0069 16.7 0.8 1.2 1 0 0 1 1 1 1 RWD domain Atrophin-1 PF03154.15 EGE02995.1 - 0.012 13.9 1.9 0.012 13.9 1.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family PIEZO PF15917.5 EGE02995.1 - 0.082 12.4 1.3 0.092 12.2 1.3 1.1 1 0 0 1 1 1 0 Piezo SRP-alpha_N PF04086.13 EGE02995.1 - 0.49 10.3 4.2 0.55 10.1 4.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3915 PF13054.6 EGE02995.1 - 2.8 7.9 6.0 4.5 7.3 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) ThiC_Rad_SAM PF01964.18 EGE02997.1 - 0.17 10.6 0.0 0.19 10.4 0.0 1.0 1 0 0 1 1 1 0 Radical SAM ThiC family P_proprotein PF01483.20 EGE02998.1 - 7.4e-29 99.6 0.9 1.4e-28 98.8 0.9 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 EGE02998.1 - 6e-26 91.4 1.5 8.6e-26 90.9 1.5 1.2 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.28 EGE02999.1 - 0.0004 20.9 0.1 0.00074 20.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PX PF00787.24 EGE03001.1 - 8.8e-19 67.6 0.4 2.2e-18 66.3 0.4 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EGE03001.1 - 2e-12 47.2 7.3 3.5e-06 26.7 0.1 2.1 1 1 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.12 EGE03001.1 - 0.031 14.3 0.4 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 EGE03001.1 - 0.14 12.9 2.9 2 9.2 0.0 2.8 3 0 0 3 3 3 0 Occludin homology domain Squash PF00299.18 EGE03002.1 - 0.00094 19.2 0.5 0.0025 17.8 0.5 1.7 1 0 0 1 1 1 1 Squash family serine protease inhibitor FAD_binding_3 PF01494.19 EGE03003.1 - 1.1e-21 77.5 0.0 1.2e-19 70.8 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGE03003.1 - 0.00014 21.1 0.0 0.0045 16.1 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGE03003.1 - 0.0039 16.5 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE03003.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 EGE03003.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 EGE03003.1 - 0.015 14.9 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE03003.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGE03003.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) tRNA-synt_His PF13393.6 EGE03004.1 - 1.9e-36 125.9 0.0 3e-30 105.5 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGE03004.1 - 1.7e-13 50.5 0.0 3.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGE03004.1 - 4.2e-05 23.6 0.0 8.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 EGE03004.1 - 0.0055 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Ribosomal_60s PF00428.19 EGE03004.1 - 0.34 11.5 2.6 1.5 9.4 0.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein dUTPase PF00692.19 EGE03005.1 - 2e-08 34.0 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 dUTPase DUF3246 PF11596.8 EGE03005.1 - 0.022 14.2 0.3 0.027 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) UCH PF00443.29 EGE03007.1 - 5.3e-55 186.7 0.6 5.3e-55 186.7 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE03007.1 - 2.6e-27 96.3 1.5 1.4e-26 93.9 1.5 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CAF-1_p150 PF11600.8 EGE03007.1 - 1.9 8.2 29.9 6.3 6.5 29.9 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop53 PF07767.11 EGE03007.1 - 2.3 7.5 25.3 1.1 8.6 21.7 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.11 EGE03007.1 - 7.2 5.0 17.9 13 4.1 17.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.10 EGE03008.1 - 8.8e-33 112.4 0.2 1e-32 112.2 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 EGE03009.1 - 1.3e-36 126.7 13.8 1.8e-36 126.3 13.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 EGE03009.1 - 4 7.8 16.2 0.051 13.9 3.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Dynamitin PF04912.14 EGE03010.1 - 8.5e-73 245.9 11.3 4e-71 240.4 11.3 2.2 1 1 0 1 1 1 1 Dynamitin APG6_N PF17675.1 EGE03010.1 - 0.0013 19.2 11.8 0.69 10.4 2.1 3.3 3 0 0 3 3 3 2 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EGE03010.1 - 0.003 17.8 11.4 0.012 15.9 0.7 3.0 3 0 0 3 3 3 1 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EGE03010.1 - 0.0038 17.3 2.8 0.0038 17.3 2.8 3.7 5 0 0 5 5 3 1 TPR/MLP1/MLP2-like protein SOGA PF11365.8 EGE03010.1 - 0.0048 18.0 6.2 0.13 13.4 0.6 3.2 3 0 0 3 3 3 1 Protein SOGA DivIC PF04977.15 EGE03010.1 - 0.0051 16.5 13.3 0.034 13.9 1.2 3.5 3 0 0 3 3 3 1 Septum formation initiator MnmE_helical PF12631.7 EGE03010.1 - 0.0086 16.3 3.1 0.08 13.1 0.2 2.2 2 0 0 2 2 2 1 MnmE helical domain DUF4407 PF14362.6 EGE03010.1 - 0.013 14.8 14.1 0.51 9.7 7.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2408 PF10303.9 EGE03010.1 - 0.014 16.0 3.9 0.79 10.3 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) SKA2 PF16740.5 EGE03010.1 - 0.022 14.5 3.3 0.36 10.6 0.0 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DHR10 PF18595.1 EGE03010.1 - 0.023 14.8 1.6 0.023 14.8 1.6 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain pPIWI_RE_REase PF18154.1 EGE03010.1 - 0.035 14.1 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 REase associating with pPIWI_RE DUF2203 PF09969.9 EGE03010.1 - 0.04 14.6 7.3 0.48 11.2 0.7 3.7 3 1 1 4 4 3 0 Uncharacterized conserved protein (DUF2203) DUF4618 PF15397.6 EGE03010.1 - 0.056 12.9 2.4 0.95 8.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 EGE03010.1 - 0.094 13.1 11.1 0.59 10.5 3.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 EGE03010.1 - 0.1 12.6 0.4 0.1 12.6 0.4 3.0 4 1 1 5 5 3 0 Laminin Domain II DUF812 PF05667.11 EGE03010.1 - 0.12 11.3 4.7 0.025 13.5 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ADIP PF11559.8 EGE03010.1 - 0.15 12.2 9.0 0.89 9.6 0.5 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EGE03010.1 - 0.17 12.5 16.0 0.2 12.3 1.7 4.4 4 1 0 4 4 4 0 SlyX HZS_alpha PF18582.1 EGE03010.1 - 0.19 12.2 0.1 0.83 10.2 0.0 2.0 2 0 0 2 2 1 0 Hydrazine synthase alpha subunit middle domain FH2 PF02181.23 EGE03010.1 - 0.26 10.3 3.7 0.16 11.0 0.2 2.3 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF16 PF01519.16 EGE03010.1 - 0.27 11.7 4.5 0.19 12.2 0.7 2.6 3 0 0 3 3 2 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 EGE03010.1 - 0.31 11.0 7.7 4.1 7.3 0.4 2.7 3 0 0 3 3 2 0 Axonemal dynein light chain OmpH PF03938.14 EGE03010.1 - 0.36 11.1 11.3 0.36 11.2 2.5 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Muted PF14942.6 EGE03010.1 - 0.42 11.0 9.0 2 8.8 0.8 3.2 2 1 1 3 3 3 0 Organelle biogenesis, Muted-like protein LPP PF04728.13 EGE03010.1 - 0.44 11.0 13.8 0.54 10.7 0.6 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Prefoldin_2 PF01920.20 EGE03010.1 - 0.49 10.4 12.6 2.3 8.2 3.4 3.5 3 1 0 3 3 3 0 Prefoldin subunit KxDL PF10241.9 EGE03010.1 - 0.56 10.5 3.4 0.54 10.6 0.4 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein Spc7 PF08317.11 EGE03010.1 - 0.65 8.8 10.7 0.14 11.0 2.1 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein Cob_adeno_trans PF01923.18 EGE03010.1 - 0.66 10.1 4.2 36 4.5 0.5 3.1 3 0 0 3 3 3 0 Cobalamin adenosyltransferase DUF1664 PF07889.12 EGE03010.1 - 0.69 10.0 3.4 0.72 9.9 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Spectrin PF00435.21 EGE03010.1 - 0.7 10.4 8.1 21 5.7 1.7 3.4 3 0 0 3 3 3 0 Spectrin repeat Golgin_A5 PF09787.9 EGE03010.1 - 0.71 9.3 6.8 0.45 9.9 1.0 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Atg14 PF10186.9 EGE03010.1 - 0.92 8.5 6.9 2.8 6.9 0.4 2.6 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 EGE03010.1 - 1.1 9.6 13.2 6.2 7.2 1.7 3.4 3 0 0 3 3 3 0 Csm1 N-terminal domain Cnn_1N PF07989.11 EGE03010.1 - 1.3 9.2 8.3 4.8 7.4 0.7 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 EGE03010.1 - 1.6 9.2 15.8 7.7 7.0 0.7 4.1 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FliD_C PF07195.12 EGE03010.1 - 1.8 7.9 4.9 0.8 9.1 2.1 1.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spc24 PF08286.11 EGE03010.1 - 1.9 8.8 12.7 4.8 7.5 0.6 3.6 4 0 0 4 4 3 0 Spc24 subunit of Ndc80 DUF4337 PF14235.6 EGE03010.1 - 1.9 8.6 10.0 3.4 7.8 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Fmp27_WPPW PF10359.9 EGE03010.1 - 2.2 7.0 6.3 2.2 7.0 0.4 2.7 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain COG2 PF06148.11 EGE03010.1 - 2.4 8.3 4.4 2.7 8.1 0.3 2.7 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 EGE03010.1 - 2.5 8.6 12.5 25 5.4 3.3 3.6 3 0 0 3 3 3 0 Cell division protein ZapB GrpE PF01025.19 EGE03010.1 - 2.7 7.6 7.6 16 5.1 0.7 3.1 3 0 0 3 3 3 0 GrpE JIP_LZII PF16471.5 EGE03010.1 - 2.8 8.2 13.8 0.56 10.4 3.6 3.4 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Snapin_Pallidin PF14712.6 EGE03010.1 - 3.1 8.3 8.8 5.4 7.5 1.5 4.2 4 1 0 4 4 4 0 Snapin/Pallidin BLOC1_2 PF10046.9 EGE03010.1 - 3.4 8.0 6.2 2.7 8.3 0.4 3.3 4 1 0 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Hsk3 PF08227.11 EGE03010.1 - 9 6.8 6.9 14 6.2 2.0 3.2 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like MbeD_MobD PF04899.12 EGE03010.1 - 9.2 6.5 7.3 0.88 9.7 0.7 2.7 4 0 0 4 4 2 0 MbeD/MobD like Peptidase_M24 PF00557.24 EGE03012.1 - 4e-39 134.5 0.4 5.8e-39 133.9 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aldedh PF00171.22 EGE03013.1 - 9.5e-138 459.6 0.8 1.3e-137 459.1 0.8 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EGE03013.1 - 0.036 14.0 0.6 0.071 13.0 0.6 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Calreticulin PF00262.18 EGE03014.1 - 7.8e-172 571.2 15.4 7.8e-172 571.2 15.4 1.7 2 0 0 2 2 2 1 Calreticulin family Aldolase_II PF00596.21 EGE03015.1 - 4e-43 147.5 0.0 4.6e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.10 EGE03016.1 - 2.1e-89 299.1 4.0 2.1e-89 299.1 4.0 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EGE03016.1 - 1.7e-25 89.2 0.2 4.3e-25 87.9 0.0 1.8 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EGE03016.1 - 0.02 14.6 6.1 0.14 11.9 2.5 2.5 1 1 1 2 2 2 0 BAR domain of APPL family BAR_2 PF10455.9 EGE03016.1 - 0.074 12.2 2.1 0.12 11.5 2.1 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking NifQ PF04891.12 EGE03016.1 - 0.31 11.4 1.9 0.69 10.3 1.9 1.5 1 0 0 1 1 1 0 NifQ PilJ PF13675.6 EGE03016.1 - 0.73 9.9 5.6 0.26 11.3 0.4 2.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribosomal_60s PF00428.19 EGE03017.1 - 0.25 11.9 6.8 0.48 11.0 6.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Flavin_Reduct PF01613.18 EGE03018.1 - 3.2e-23 82.5 1.9 8.5e-23 81.1 1.9 1.7 1 1 0 1 1 1 1 Flavin reductase like domain Tweety PF04906.13 EGE03019.1 - 3.2 6.3 6.1 3 6.4 4.8 1.5 1 1 1 2 2 2 0 Tweety Atg14 PF10186.9 EGE03019.1 - 5.2 6.0 21.0 15 4.6 21.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 4HBT_2 PF13279.6 EGE03020.1 - 1.5e-20 73.9 0.0 2.5e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EGE03020.1 - 0.037 14.4 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily PspB PF06667.12 EGE03020.1 - 0.046 13.8 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B Complex1_LYR_2 PF13233.6 EGE03021.1 - 6.2e-06 26.9 1.0 8.1e-06 26.5 1.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGE03021.1 - 1.8e-05 24.7 0.2 2.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_25 PF13649.6 EGE03022.1 - 1.6e-12 47.9 0.0 3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03022.1 - 8.9e-11 42.3 0.0 2.7e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE03022.1 - 3.6e-08 33.3 0.0 5.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE03022.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGE03022.1 - 5.1e-05 23.9 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE03022.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Mucin PF01456.17 EGE03022.1 - 0.35 10.8 58.7 0.072 13.1 55.1 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein Tim54 PF11711.8 EGE03022.1 - 1.6 7.4 3.5 2.4 6.9 3.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FSA_C PF10479.9 EGE03022.1 - 4.3 5.4 26.2 6.1 4.9 26.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Macoilin PF09726.9 EGE03022.1 - 9.4 4.7 10.6 13 4.2 10.6 1.1 1 0 0 1 1 1 0 Macoilin family LRR_8 PF13855.6 EGE03023.1 - 6.4e-15 54.7 27.5 1.1e-07 31.5 7.7 2.3 1 1 2 3 3 3 3 Leucine rich repeat Exo_endo_phos PF03372.23 EGE03023.1 - 9.5e-15 54.7 0.0 8.1e-14 51.7 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EGE03023.1 - 8.9e-11 41.9 9.8 2.9e-06 27.5 1.6 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGE03023.1 - 0.039 13.5 0.2 0.069 12.7 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 EGE03023.1 - 0.16 12.6 5.0 4.6 8.2 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat MFS_1 PF07690.16 EGE03024.1 - 1.6e-44 152.3 47.9 4.1e-44 150.9 47.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE03024.1 - 1.6e-23 83.0 17.1 4.4e-20 71.6 15.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE03024.1 - 2e-19 69.8 0.9 2e-19 69.8 0.9 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGE03024.1 - 3.3e-06 26.6 11.4 5.9e-05 22.5 4.8 2.8 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB EptA_B_N PF08019.12 EGE03024.1 - 0.0033 17.3 0.1 0.0033 17.3 0.1 2.9 4 0 0 4 4 4 1 Phosphoethanolamine transferase EptA/EptB Peptidase_M56 PF05569.11 EGE03024.1 - 0.031 13.5 0.2 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 OATP PF03137.20 EGE03024.1 - 2.1 6.5 12.3 0.068 11.5 3.6 2.7 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HET PF06985.11 EGE03025.1 - 8.2e-22 78.1 0.0 1.4e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GCD14 PF08704.10 EGE03026.1 - 3e-07 30.4 0.0 0.00064 19.5 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EGE03026.1 - 6.3e-06 25.9 2.0 1.1e-05 25.2 0.9 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 EGE03026.1 - 0.01 15.6 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03026.1 - 0.074 13.8 0.0 3.5 8.4 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03026.1 - 0.075 13.7 0.0 17 6.1 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Metallophos PF00149.28 EGE03027.1 - 7.3e-19 69.1 0.5 7.3e-19 69.1 0.5 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE03027.1 - 1.6e-06 28.4 0.0 0.002 18.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.12 EGE03028.1 - 4e-05 23.8 0.5 0.0007 19.7 0.2 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EGE03028.1 - 5.6e-05 23.7 0.0 0.013 16.2 0.0 2.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain SopE_GEF PF07487.13 EGE03028.1 - 0.2 11.7 0.0 0.38 10.9 0.0 1.3 1 0 0 1 1 1 0 SopE GEF domain MARVEL PF01284.23 EGE03029.1 - 0.0013 18.8 2.4 0.0019 18.2 2.4 1.4 1 0 0 1 1 1 1 Membrane-associating domain SHR3_chaperone PF08229.11 EGE03029.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 CD20 PF04103.15 EGE03029.1 - 0.17 12.0 2.5 0.38 10.8 2.5 1.5 1 1 0 1 1 1 0 CD20-like family COesterase PF00135.28 EGE03030.1 - 3.1e-55 188.0 0.0 5.2e-55 187.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE03030.1 - 1.4e-06 28.4 0.1 4.3e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 EGE03031.1 - 1.7e-47 161.3 1.4 6.2e-47 159.4 1.4 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 EGE03031.1 - 2.9e-43 146.2 0.2 7.4e-12 45.5 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EGE03031.1 - 2.9e-16 60.4 0.3 1.6e-09 38.3 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE03031.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase B12-binding PF02310.19 EGE03031.1 - 0.029 14.4 0.0 2.4 8.2 0.0 3.5 4 0 0 4 4 4 0 B12 binding domain zinc_ribbon_12 PF11331.8 EGE03031.1 - 0.038 13.8 2.0 21 5.0 0.2 3.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain Flu_M2 PF00599.17 EGE03032.1 - 0.18 11.9 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M2) CSN7a_helixI PF18392.1 EGE03033.1 - 0.0017 18.2 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 EGE03033.1 - 0.0043 17.5 0.0 0.0068 16.9 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.19 EGE03034.1 - 5.4e-13 49.2 0.0 4.4e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 EGE03035.1 - 1.1e-24 86.3 1.0 2.3e-24 85.3 1.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGE03035.1 - 3.2e-08 33.8 0.0 6.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE03035.1 - 1.1e-06 28.7 0.1 1.9e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE03035.1 - 0.00036 20.9 0.1 0.00064 20.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 EGE03036.1 - 2.5e-19 69.3 9.0 2.9e-19 69.1 9.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 EGE03037.1 - 3.4e-88 295.3 0.1 4e-88 295.1 0.1 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.6 EGE03038.1 - 1.9e-35 123.2 1.5 1.9e-35 123.2 1.5 3.0 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EGE03038.1 - 9.8e-17 61.7 0.4 3.6e-14 53.3 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGE03038.1 - 6.7e-15 55.1 19.2 4.1e-08 32.9 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGE03038.1 - 2.1e-09 37.6 4.3 0.001 18.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGE03038.1 - 4.7e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGE03038.1 - 0.00034 20.3 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE03038.1 - 0.017 15.5 0.0 0.017 15.5 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran_CTD PF16326.5 EGE03038.1 - 0.022 15.0 1.5 0.022 15.0 1.5 4.7 4 2 2 6 6 6 0 ABC transporter C-terminal domain ABC_tran PF00005.27 EGE03038.1 - 0.032 14.7 13.6 3.5e+02 1.7 13.6 4.1 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EGE03038.1 - 0.048 13.9 0.1 0.048 13.9 0.1 3.2 3 1 0 3 3 3 0 AAA domain PPP4R2 PF09184.11 EGE03039.1 - 3e-11 43.5 0.0 5.7e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 PPP4R2 DUF3480 PF11979.8 EGE03040.1 - 0.027 13.4 0.1 0.99 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) zf-C2H2 PF00096.26 EGE03041.1 - 1.7e-12 47.1 13.9 3.9e-06 27.0 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE03041.1 - 7.2e-11 42.0 10.1 1.4e-06 28.4 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE03041.1 - 1.4e-08 34.8 11.4 0.00092 19.9 1.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGE03041.1 - 8.6e-07 28.8 5.2 0.0022 17.9 0.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE03041.1 - 5.1e-06 26.6 0.2 0.067 13.5 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGE03041.1 - 0.00018 21.8 1.4 0.013 15.9 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGE03041.1 - 0.00031 20.4 5.6 0.094 12.5 0.6 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EGE03041.1 - 0.019 15.4 1.3 0.048 14.2 1.3 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EGE03041.1 - 0.093 13.0 1.6 0.19 12.1 1.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EGE03041.1 - 0.16 12.4 2.1 4.1 7.9 0.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EGE03041.1 - 0.74 10.1 2.3 14 6.0 0.2 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 EGE03041.1 - 2.4 8.4 6.3 18 5.6 1.2 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain Pkinase PF00069.25 EGE03042.1 - 6e-52 176.6 0.2 1.1e-33 116.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03042.1 - 1.7e-25 89.8 0.0 3.5e-24 85.5 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE03042.1 - 7.6e-05 21.6 0.0 0.00021 20.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE03042.1 - 0.00093 19.2 0.1 0.0064 16.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE03042.1 - 0.0017 17.8 0.0 0.0044 16.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kelch_4 PF13418.6 EGE03044.1 - 2.6e-05 24.1 0.4 0.028 14.4 0.0 3.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE03044.1 - 0.00048 20.3 0.9 0.27 11.6 0.0 4.5 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 EGE03044.1 - 0.0008 19.3 0.0 0.062 13.3 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EGE03044.1 - 0.00081 19.6 2.6 0.89 9.9 0.1 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Mid2 PF04478.12 EGE03044.1 - 0.0011 18.9 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Kelch_2 PF07646.15 EGE03044.1 - 0.003 17.5 1.2 0.74 9.9 0.0 4.1 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.10 EGE03044.1 - 0.0033 16.8 4.0 0.0066 15.8 4.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BPL_LplA_LipB PF03099.19 EGE03045.1 - 7.7e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 EGE03046.1 - 1.5e-139 464.3 0.0 1.7e-139 464.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.9 EGE03047.1 - 7.3e-19 69.0 19.5 2.3e-13 51.2 2.3 3.0 2 1 1 3 3 3 2 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.7 EGE03047.1 - 0.37 10.8 9.0 0.05 13.6 4.3 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EGE03047.1 - 0.52 10.3 2.8 0.78 9.7 1.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-RanBP PF00641.18 EGE03047.1 - 2 7.8 9.8 0.071 12.4 0.6 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Alg14 PF08660.11 EGE03048.1 - 2.7e-53 180.5 0.0 3.5e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like ODV-E18 PF10717.9 EGE03049.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 EGE03049.1 - 0.18 12.7 3.6 3.1 8.7 1.2 2.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.8 EGE03049.1 - 0.4 11.1 2.6 0.5 10.8 2.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF1180 PF06679.12 EGE03050.1 - 1.1 9.6 6.5 0.41 11.0 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1180) PNK3P PF08645.11 EGE03052.1 - 1.8e-42 144.8 0.4 5.3e-42 143.3 0.4 1.8 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGE03052.1 - 1e-11 45.2 0.0 3.1e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGE03052.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PGP_phosphatase PF09419.10 EGE03052.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Med18 PF09637.10 EGE03053.1 - 8.3e-43 147.0 0.0 9.3e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 EGE03054.1 - 2.8e-42 144.9 0.4 3.3e-42 144.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 EGE03055.1 - 9.8e-68 228.4 9.0 1.1e-55 189.0 4.5 3.2 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis RGS PF00615.19 EGE03058.1 - 2.4e-11 43.9 0.0 4.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 EGE03059.1 - 1.6e-14 53.9 0.0 2.2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGE03059.1 - 8.7e-08 31.3 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGE03059.1 - 4.6e-05 22.8 0.0 6.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AICARFT_IMPCHas PF01808.18 EGE03060.1 - 6e-91 305.0 0.0 1.2e-90 303.9 0.0 1.5 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGE03060.1 - 5.1e-25 87.5 0.1 9.1e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 MGS-like domain Rtt106 PF08512.12 EGE03061.1 - 9.9e-31 106.0 0.0 1.9e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EGE03061.1 - 0.012 15.6 0.0 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PPP4R2 PF09184.11 EGE03061.1 - 4.9 6.7 14.0 7.3 6.1 14.0 1.3 1 0 0 1 1 1 0 PPP4R2 KOW PF00467.29 EGE03062.1 - 2.1e-06 27.5 0.5 4.2e-06 26.5 0.5 1.5 1 0 0 1 1 1 1 KOW motif SH3_13 PF18335.1 EGE03062.1 - 0.086 12.7 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Ras PF00071.22 EGE03063.1 - 4.3e-47 159.7 0.0 1.5e-42 145.0 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGE03063.1 - 9.8e-19 67.7 0.0 1.2e-13 51.3 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase baeRF_family3 PF18845.1 EGE03063.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.4 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 EGE03063.1 - 0.084 12.0 0.0 6.7 5.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.9 EGE03063.1 - 0.11 12.2 0.0 7.7 6.3 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MGC-24 PF05283.11 EGE03064.1 - 2.2e-05 24.9 0.2 2.2e-05 24.9 0.2 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Podoplanin PF05808.11 EGE03064.1 - 0.00032 20.8 0.3 0.00073 19.7 0.0 1.6 2 0 0 2 2 2 1 Podoplanin AJAP1_PANP_C PF15298.6 EGE03064.1 - 0.11 12.7 0.2 0.11 12.7 0.2 1.4 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Syndecan PF01034.20 EGE03064.1 - 0.19 11.6 1.0 0.35 10.8 1.0 1.3 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.13 EGE03064.1 - 0.2 10.5 0.5 0.33 9.8 0.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4690 PF15756.5 EGE03064.1 - 0.38 11.4 5.1 0.14 12.7 1.0 2.3 2 0 0 2 2 2 0 Small Novel Rich in Cartilage SKG6 PF08693.10 EGE03064.1 - 0.44 10.0 3.9 1.2 8.6 3.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pex14_N PF04695.13 EGE03064.1 - 1 10.0 6.6 0.27 11.9 0.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4124 PF13511.6 EGE03064.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4124) Aldedh PF00171.22 EGE03065.1 - 2.1e-145 484.8 0.0 2.6e-145 484.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1712 PF08217.11 EGE03066.1 - 9.7e-19 67.3 0.0 3.1e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 EGE03067.1 - 6.6e-23 81.4 0.0 9.7e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase adh_short_C2 PF13561.6 EGE03068.1 - 5e-43 147.3 0.1 6.2e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE03068.1 - 3.5e-42 144.1 0.1 4.5e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE03068.1 - 1.1e-11 44.9 0.3 1.6e-11 44.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE03068.1 - 0.011 15.3 0.2 0.06 12.8 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGE03068.1 - 0.022 13.9 0.0 0.087 11.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein EMP24_GP25L PF01105.24 EGE03069.1 - 4.7e-51 173.3 0.0 6.1e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_S46 PF10459.9 EGE03069.1 - 0.061 12.0 0.7 0.13 10.9 0.2 1.6 1 1 1 2 2 2 0 Peptidase S46 TMEMspv1-c74-12 PF11044.8 EGE03069.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein PspB PF06667.12 EGE03069.1 - 0.2 11.7 0.5 0.42 10.7 0.5 1.6 1 0 0 1 1 1 0 Phage shock protein B SANT_DAMP1_like PF16282.5 EGE03070.1 - 1.3e-30 105.4 1.3 2.5e-30 104.5 1.3 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EGE03070.1 - 0.0006 19.7 4.6 0.0006 19.7 4.6 3.0 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 EGE03070.1 - 0.11 12.7 0.0 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain UPF0242 PF06785.11 EGE03070.1 - 0.51 10.4 9.3 0.26 11.4 1.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rz1 PF06085.11 EGE03072.1 - 0.57 10.0 3.1 7.3 6.4 3.1 2.5 1 1 0 1 1 1 0 Lipoprotein Rz1 precursor Meth_synt_2 PF01717.18 EGE03073.1 - 5.7e-152 505.6 0.0 1.3e-148 494.5 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGE03073.1 - 2.6e-118 395.1 0.0 1.9e-112 375.9 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGE03073.1 - 2.3e-05 23.7 0.1 0.012 14.8 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 EGE03073.1 - 0.0043 16.9 0.1 2 8.3 0.0 2.8 2 0 0 2 2 2 2 Antitoxin VbhA Steroid_dh PF02544.16 EGE03074.1 - 7.3e-09 35.8 2.9 0.0056 16.7 0.1 4.0 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGE03074.1 - 0.015 14.9 0.3 0.1 12.1 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.9 EGE03075.1 - 3.2e-207 690.0 14.8 3.9e-207 689.7 14.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EGE03075.1 - 7.2e-28 96.6 1.8 3.6e-27 94.3 0.4 2.6 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.11 EGE03076.1 - 1.4e-31 108.8 0.1 2.6e-31 108.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EGE03076.1 - 1.5e-22 79.5 0.4 2.6e-22 78.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EGE03077.1 - 8.5e-06 26.1 1.0 1.8e-05 25.0 0.1 1.7 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 CTP_transf_like PF01467.26 EGE03078.1 - 0.00055 20.2 0.1 0.0015 18.8 0.1 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like Ydc2-catalyt PF09159.10 EGE03080.1 - 7.8e-94 314.5 0.0 9.8e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 EGE03080.1 - 6.2e-05 22.6 0.6 0.00015 21.4 0.6 1.7 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 EGE03080.1 - 7.2e-05 22.9 0.0 2.1 8.4 0.0 3.4 3 0 0 3 3 3 2 Poxvirus A22 protein Tcp11 PF05794.13 EGE03081.1 - 4.2e-96 322.7 0.0 6.2e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 11 LIN37 PF15306.6 EGE03081.1 - 2.9 8.1 6.7 2.7 8.2 5.2 1.7 1 1 0 1 1 1 0 LIN37 Peptidase_S10 PF00450.22 EGE03082.1 - 1e-77 262.3 0.0 1.2e-77 262.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SOG2 PF10428.9 EGE03083.1 - 3e-83 280.7 6.3 3e-83 280.7 6.3 3.3 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.7 EGE03083.1 - 3e-13 49.7 5.0 4.8e-05 23.6 0.5 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGE03083.1 - 1.3e-12 47.3 6.3 2.3e-07 30.5 0.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EGE03083.1 - 0.016 15.7 6.7 34 5.5 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EGE03083.1 - 0.035 14.2 5.2 2.9 8.2 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S25 PF13741.6 EGE03084.1 - 1.7e-79 266.6 6.0 2.1e-79 266.3 6.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EGE03084.1 - 0.059 13.6 3.3 3.6 7.9 0.0 2.9 1 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 EGE03085.1 - 6e-10 39.2 0.3 0.0097 16.1 0.0 4.7 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 EGE03085.1 - 3.8e-07 29.9 1.1 0.25 11.7 0.1 4.4 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGE03085.1 - 0.0014 18.1 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ESSS PF10183.9 EGE03085.1 - 0.032 14.4 0.1 0.087 13.1 0.1 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PPR_3 PF13812.6 EGE03085.1 - 0.087 12.9 0.2 4.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DEAD PF00270.29 EGE03086.1 - 1.1e-16 61.1 0.0 5.1e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03086.1 - 1.5e-13 51.1 0.0 1.8e-10 41.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EGE03086.1 - 2.5e-05 24.9 1.9 7.3e-05 23.4 1.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding KH_1 PF00013.29 EGE03087.1 - 4.7e-07 29.6 0.0 3.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 KH domain ALS_ss_C PF10369.9 EGE03088.1 - 2.8e-15 56.3 0.0 6.6e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EGE03088.1 - 2.1e-12 46.6 0.2 3.7e-12 45.8 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EGE03088.1 - 5e-08 32.7 0.0 9.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EGE03088.1 - 0.03 14.3 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 ACT domain Cu-oxidase_3 PF07732.15 EGE03091.1 - 4.4e-42 142.8 0.1 8.3e-41 138.7 0.2 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE03091.1 - 3.7e-38 130.3 7.0 3.6e-35 120.7 0.9 3.9 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE03091.1 - 1.4e-25 90.3 0.0 9.6e-25 87.5 0.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Ehbp PF10622.9 EGE03092.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) DUF3712 PF12505.8 EGE03093.1 - 3.4e-07 30.6 0.8 0.048 13.9 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) OTCace PF00185.24 EGE03094.1 - 9.8e-45 152.4 0.0 1.6e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EGE03094.1 - 2.1e-44 151.2 0.1 3e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF3984 PF13136.6 EGE03095.1 - 5.7e-104 348.1 23.0 8.3e-104 347.5 23.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Ndc1_Nup PF09531.10 EGE03096.1 - 1.1e-196 655.2 2.1 1.2e-196 655.1 2.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EGE03097.1 - 2.9e-23 82.2 7.5 3.3e-23 81.9 2.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGE03097.1 - 9.8e-15 54.3 1.9 9.8e-15 54.3 1.9 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EGE03097.1 - 1.4e-06 28.2 7.9 2.4e-06 27.4 7.9 1.5 1 1 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 EGE03097.1 - 0.00024 20.8 0.8 0.0011 18.8 0.3 2.3 2 1 0 2 2 2 1 Synaptobrevin T3SSipB PF16535.5 EGE03097.1 - 0.01 16.3 4.5 0.061 13.8 3.1 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF334 PF03904.13 EGE03097.1 - 0.014 15.0 3.5 0.27 10.7 1.5 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF334) SepF PF04472.12 EGE03097.1 - 0.056 13.7 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Cell division protein SepF DUF883 PF05957.13 EGE03097.1 - 0.092 13.4 9.7 0.57 10.8 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 EGE03097.1 - 0.25 11.5 2.2 1 9.5 0.1 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF5345 PF17280.2 EGE03097.1 - 0.59 10.2 0.1 0.59 10.2 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5345) DUF16 PF01519.16 EGE03097.1 - 0.93 10.0 6.1 0.97 10.0 0.8 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 Cyto_heme_lyase PF01265.17 EGE03098.1 - 1.2e-39 136.7 6.1 2.4e-35 122.6 0.2 2.6 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 EGE03100.1 - 8.2e-62 208.3 0.0 1.1e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGE03100.1 - 2.6e-10 40.4 1.7 6.7e-10 39.1 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain IKI3 PF04762.12 EGE03101.1 - 9.4e-293 973.7 0.0 1.1e-292 973.5 0.0 1.0 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGE03101.1 - 0.00023 21.4 0.2 2 8.8 0.0 4.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain COX7C PF02935.16 EGE03102.1 - 1.3e-21 76.6 5.5 2.1e-21 75.9 5.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 EGE03103.1 - 2.8e-92 309.5 1.0 7.1e-92 308.2 1.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EGE03103.1 - 1.3e-54 184.3 1.2 1.3e-54 184.3 1.2 2.1 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 EGE03103.1 - 8.6e-19 68.0 0.1 3.2e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03103.1 - 3.9e-06 27.2 0.1 2.5e-05 24.6 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03103.1 - 2.3e-05 24.5 0.0 5.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EGE03103.1 - 0.037 13.1 0.0 0.097 11.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EGE03103.1 - 0.076 12.9 0.2 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF5388 PF17363.2 EGE03103.1 - 0.11 12.7 0.6 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5388) AAA_22 PF13401.6 EGE03103.1 - 0.14 12.5 0.1 0.75 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cut8 PF08559.10 EGE03104.1 - 1.3e-46 159.2 0.2 1.6e-46 158.9 0.2 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein HalOD1 PF18545.1 EGE03104.1 - 0.052 13.8 0.1 0.096 13.0 0.1 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 Motile_Sperm PF00635.26 EGE03105.1 - 2.7e-25 88.3 0.1 5.2e-25 87.4 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain Trypan_PARP PF05887.11 EGE03105.1 - 0.0029 17.6 2.0 0.005 16.8 2.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ASH PF15780.5 EGE03105.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 EGE03106.1 - 1.4e-05 25.2 0.1 5.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 EGE03106.1 - 0.0018 18.1 0.0 0.0086 16.0 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_6 PF13912.6 EGE03106.1 - 0.073 13.1 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Exonuc_VII_L PF02601.15 EGE03106.1 - 0.082 12.5 12.4 0.11 12.0 12.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Utp11 PF03998.13 EGE03106.1 - 0.12 12.3 28.7 0.17 11.8 28.7 1.2 1 0 0 1 1 1 0 Utp11 protein GATA PF00320.27 EGE03106.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2 PF00096.26 EGE03106.1 - 0.17 12.4 0.2 0.32 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGE03106.1 - 2.6 8.4 6.5 0.27 11.6 0.3 2.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FapA PF03961.13 EGE03106.1 - 3.1 6.3 21.1 5 5.6 21.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A LMBR1 PF04791.16 EGE03106.1 - 6.5 5.5 14.0 7.4 5.4 14.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rad52_Rad22 PF04098.15 EGE03107.1 - 6.1e-57 191.8 0.0 9.7e-57 191.2 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UPF0449 PF15136.6 EGE03108.1 - 0.034 14.6 0.3 0.16 12.5 0.3 2.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Aa_trans PF01490.18 EGE03109.1 - 2.7e-71 240.4 28.7 3.2e-71 240.2 28.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3043 PF11241.8 EGE03109.1 - 0.33 10.9 3.2 30 4.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3043) Trypsin_2 PF13365.6 EGE03110.1 - 9.8e-07 29.8 0.0 2.2e-05 25.4 0.0 2.9 3 1 0 3 3 3 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGE03110.1 - 0.00026 19.6 0.0 0.00036 19.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 EGE03110.1 - 0.00082 18.6 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Nup54_57_C PF18570.1 EGE03110.1 - 0.14 11.8 0.4 0.27 10.9 0.4 1.4 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain SIR4_SID PF16991.5 EGE03111.1 - 0.091 12.8 1.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Sir4 SID domain Y_phosphatase2 PF03162.13 EGE03112.1 - 2.1e-42 144.5 0.0 3e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGE03112.1 - 8.3e-09 35.7 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EGE03112.1 - 4.9e-06 26.4 0.0 6.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE03112.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGE03112.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1133 PF06576.11 EGE03112.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) TatD_DNase PF01026.21 EGE03114.1 - 2.8e-48 164.5 0.0 3.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 EGE03115.1 - 8e-113 377.0 0.0 9.7e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGE03115.1 - 1.7e-17 63.3 0.0 3.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGE03115.1 - 0.00045 19.5 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EGE03115.1 - 0.00057 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EGE03115.1 - 0.00068 19.0 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EGE03115.1 - 0.013 14.5 0.4 0.033 13.2 0.4 1.7 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain CbiJ PF02571.14 EGE03115.1 - 0.081 12.4 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK SAP PF02037.27 EGE03117.1 - 2.7e-09 36.6 0.0 4.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SAP domain HHV-1_VABD PF16852.5 EGE03117.1 - 0.07 13.1 0.2 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain PCMT PF01135.19 EGE03117.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNA_pol_Rpb1_1 PF04997.12 EGE03118.1 - 3.1e-82 276.4 0.0 5.5e-82 275.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGE03118.1 - 7.9e-72 240.9 0.0 1.4e-71 240.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 EGE03118.1 - 2.4e-66 223.9 0.0 2.4e-65 220.6 0.0 2.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 EGE03118.1 - 6.6e-34 117.1 0.0 1.3e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGE03118.1 - 1.7e-25 89.0 0.5 5.3e-25 87.5 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Asp PF00026.23 EGE03119.1 - 1.3e-70 238.4 0.9 1.5e-70 238.1 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGE03119.1 - 9.7e-10 39.0 0.2 3.9e-07 30.5 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE03119.1 - 0.00048 20.7 0.2 0.071 13.8 0.0 2.9 2 2 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGE03119.1 - 0.011 16.2 0.0 2 9.0 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease CarboxypepD_reg PF13620.6 EGE03120.1 - 0.014 15.7 1.1 0.17 12.1 0.2 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Vfa1 PF08432.10 EGE03121.1 - 4.6e-60 203.0 19.3 5.2e-60 202.9 19.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 EGE03121.1 - 0.00042 20.2 13.3 0.00056 19.8 13.3 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EGE03121.1 - 0.027 13.3 12.9 0.03 13.1 12.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 EGE03121.1 - 0.037 13.5 12.8 0.042 13.3 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SAPS PF04499.15 EGE03121.1 - 0.065 12.0 6.2 0.065 12.0 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPL5 PF18168.1 EGE03121.1 - 0.065 12.5 9.1 0.076 12.3 9.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 EGE03121.1 - 0.18 10.8 4.3 0.2 10.6 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF262 PF03235.14 EGE03121.1 - 0.39 10.9 6.8 0.46 10.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 DDHD PF02862.17 EGE03121.1 - 0.45 10.6 4.9 0.58 10.3 4.9 1.2 1 0 0 1 1 1 0 DDHD domain Atrophin-1 PF03154.15 EGE03121.1 - 0.71 8.1 19.9 0.95 7.7 19.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family SID-1_RNA_chan PF13965.6 EGE03121.1 - 0.89 7.9 1.9 0.99 7.7 1.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 EGE03121.1 - 1.2 8.1 11.6 1.4 7.9 11.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4407 PF14362.6 EGE03121.1 - 1.3 8.4 13.7 1.6 8.0 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 EGE03121.1 - 2.1 6.5 20.5 2.5 6.3 20.5 1.0 1 0 0 1 1 1 0 CDC45-like protein CLN3 PF02487.17 EGE03121.1 - 2.2 7.2 4.6 2.5 7.1 4.6 1.2 1 0 0 1 1 1 0 CLN3 protein Neur_chan_memb PF02932.16 EGE03121.1 - 2.2 8.3 5.5 2.5 8.1 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.12 EGE03121.1 - 2.5 5.8 14.7 2.7 5.7 14.7 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.11 EGE03121.1 - 3 6.2 22.6 3.6 6.0 22.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2722 PF10846.8 EGE03121.1 - 3.3 6.6 15.6 4.4 6.2 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) MCM_bind PF09739.9 EGE03121.1 - 3.3 6.0 13.2 4.1 5.7 13.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 EGE03121.1 - 4 6.1 13.1 4.6 5.9 13.1 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 EGE03121.1 - 4.4 7.5 26.6 7.5 6.7 26.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ATP11 PF06644.11 EGE03121.1 - 4.5 7.0 16.9 5.9 6.6 16.9 1.2 1 0 0 1 1 1 0 ATP11 protein ALMT PF11744.8 EGE03121.1 - 4.7 5.9 9.9 5.4 5.7 9.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 EGE03121.1 - 5.8 6.0 8.7 6.5 5.9 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RasGAP PF00616.19 EGE03121.1 - 7.7 6.2 11.7 10 5.8 11.7 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DSPc PF00782.20 EGE03122.1 - 1.5e-23 83.1 0.0 2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGE03122.1 - 0.0066 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EGE03122.1 - 0.059 12.9 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2 PF00096.26 EGE03123.1 - 0.014 15.8 3.3 0.014 15.8 3.3 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE03123.1 - 0.015 15.7 1.2 0.015 15.7 1.2 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGE03123.1 - 0.066 13.5 4.2 0.19 12.0 4.2 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2614 PF11023.8 EGE03123.1 - 0.15 12.2 0.3 0.24 11.5 0.3 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Cytochrome_C7 PF14522.6 EGE03123.1 - 2.2 8.4 13.0 7.5 6.6 13.0 2.0 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C2H2_4 PF13894.6 EGE03123.1 - 2.5 9.2 20.6 0.35 11.8 2.3 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger FA_desaturase PF00487.24 EGE03124.1 - 8.3e-27 94.6 8.6 1.2e-26 94.1 8.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGE03124.1 - 2.1e-17 62.3 0.7 3.9e-17 61.4 0.7 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ABC1 PF03109.16 EGE03125.1 - 5e-33 113.8 0.0 9.2e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGE03125.1 - 0.061 12.9 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Anp1 PF03452.14 EGE03126.1 - 2.8e-104 348.2 0.1 3.5e-104 347.9 0.1 1.1 1 0 0 1 1 1 1 Anp1 Ecm33 PF12454.8 EGE03127.1 - 8.4e-11 41.8 1.9 1.1e-10 41.5 0.6 1.9 1 1 1 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EGE03127.1 - 2.8e-10 40.3 2.4 0.048 13.8 0.0 4.7 1 1 2 4 4 4 4 Receptor L domain LRR_5 PF13306.6 EGE03127.1 - 0.0077 16.2 0.9 3.5 7.6 0.0 2.9 1 1 2 3 3 3 1 BspA type Leucine rich repeat region (6 copies) HhH-GPD PF00730.25 EGE03128.1 - 5.2e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HMG14_17 PF01101.18 EGE03128.1 - 0.73 10.8 10.2 1.7 9.6 10.2 1.6 1 0 0 1 1 1 0 HMG14 and HMG17 UCR_14kD PF02271.16 EGE03129.1 - 1.2e-44 150.3 0.2 1.4e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EGE03130.1 - 9e-41 137.7 2.5 9.3e-17 60.7 0.1 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein CHD5 PF04420.14 EGE03131.1 - 1.5e-33 115.9 1.9 2e-33 115.5 1.9 1.1 1 0 0 1 1 1 1 CHD5-like protein SUI1 PF01253.22 EGE03132.1 - 7.8e-19 68.0 0.0 1.9e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EGE03132.1 - 8.3e-08 32.8 0.1 6.1e-06 26.8 0.1 2.8 1 1 0 1 1 1 1 Pre-PUA-like domain Trypsin PF00089.26 EGE03133.1 - 1.4e-08 34.8 0.1 2.8e-08 33.9 0.1 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EGE03133.1 - 0.0045 17.9 0.0 0.0067 17.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain TIG PF01833.24 EGE03134.1 - 1.3e-09 38.0 0.2 3.8e-09 36.5 0.2 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.6 EGE03134.1 - 5e-09 36.2 3.1 4.9e-05 23.5 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGE03134.1 - 8.9e-09 35.4 6.2 0.0021 18.4 2.9 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGE03134.1 - 5.6e-08 33.3 0.1 1.1e-07 32.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE03134.1 - 4.1e-07 30.4 0.9 1.8e-06 28.4 0.4 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE03134.1 - 4e-06 26.7 0.9 0.066 13.8 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeat Bap31 PF05529.12 EGE03134.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region TRAPPC10 PF12584.8 EGE03135.1 - 8.8e-40 136.0 0.0 1.8e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 FA_desaturase PF00487.24 EGE03136.1 - 6.2e-23 81.9 18.3 1.7e-22 80.5 18.3 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EGE03136.1 - 8.5e-09 35.7 0.0 2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rad51 PF08423.11 EGE03137.1 - 1.2e-39 136.2 0.0 1.9e-37 128.9 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EGE03137.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGE03137.1 - 2.8e-06 26.8 0.0 8e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGE03137.1 - 0.004 16.5 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain DUF1254 PF06863.12 EGE03137.1 - 0.0047 17.0 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) RecA PF00154.21 EGE03137.1 - 0.03 13.8 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_22 PF13401.6 EGE03137.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGE03137.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain La PF05383.17 EGE03138.1 - 4.5e-21 74.7 0.0 9.3e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGE03138.1 - 2.9e-05 23.8 0.1 8.3e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.15 EGE03139.1 - 6.2e-22 77.9 2.9 6.2e-22 77.9 2.9 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGE03139.1 - 5e-15 55.9 5.8 5e-15 55.9 5.8 2.5 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGE03139.1 - 7.1e-10 39.2 0.1 2.6e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGE03139.1 - 0.0095 15.8 0.0 2.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.20 EGE03140.1 - 9.3e-167 555.8 0.1 1.3e-166 555.4 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGE03140.1 - 4.4e-11 42.2 0.3 9.2e-11 41.1 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGE03140.1 - 0.0037 17.7 0.1 0.47 10.9 0.0 3.1 2 1 0 2 2 2 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.22 EGE03140.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGE03141.1 - 1.9e-69 233.9 0.2 2.8e-69 233.4 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE03141.1 - 3e-41 139.9 0.5 6.2e-41 138.9 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGE03141.1 - 0.011 15.5 0.3 2.8 7.9 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGE03141.1 - 0.021 14.4 1.2 0.13 11.9 1.2 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain WLM PF08325.10 EGE03142.1 - 1.5e-49 168.7 0.0 2.1e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EGE03142.1 - 0.00013 22.1 0.1 0.0011 19.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 EGE03142.1 - 0.033 14.0 0.2 0.069 13.0 0.0 1.6 2 0 0 2 2 2 0 SprT-like family LicD PF04991.13 EGE03143.1 - 7e-22 78.7 1.1 1.1e-17 65.0 1.9 2.1 1 1 1 2 2 2 2 LicD family HNH_2 PF13391.6 EGE03145.1 - 4.4e-11 42.7 0.0 1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DASH_Ask1 PF08655.10 EGE03146.1 - 1.6e-30 104.7 1.0 2.8e-30 104.0 1.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 RhoGAP PF00620.27 EGE03147.1 - 5.2e-46 156.2 0.1 1.7e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EGE03147.1 - 8.3e-14 51.6 18.5 3e-09 37.0 2.7 2.5 2 0 0 2 2 2 2 LIM domain CENP-H PF05837.12 EGE03147.1 - 0.073 13.5 0.2 0.073 13.5 0.2 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) OrfB_Zn_ribbon PF07282.11 EGE03147.1 - 8.9 6.3 16.4 0.19 11.7 0.6 3.6 3 1 1 4 4 4 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EGE03147.1 - 9 5.9 17.6 33 4.1 0.1 4.4 3 1 0 3 3 3 0 TFIIB zinc-binding 4HBT PF03061.22 EGE03149.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT_3 PF13622.6 EGE03149.1 - 0.024 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Carn_acyltransf PF00755.20 EGE03150.1 - 1.3e-198 661.4 0.0 1.6e-198 661.1 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase JmjC PF02373.22 EGE03151.1 - 3.2e-38 130.7 1.3 5e-38 130.0 0.5 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 EGE03151.1 - 1.3e-18 67.1 2.9 2.5e-18 66.1 2.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGE03151.1 - 4.3e-18 65.5 3.0 7.3e-18 64.7 3.0 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 EGE03151.1 - 9.3e-14 51.1 0.3 2.3e-13 49.8 0.3 1.8 1 0 0 1 1 1 1 jmjN domain UQ_con PF00179.26 EGE03152.1 - 1.9e-22 79.5 0.0 3.2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AA_permease_2 PF13520.6 EGE03153.1 - 1.2e-65 222.1 53.0 1.4e-65 221.8 53.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE03153.1 - 8.6e-32 110.3 47.0 1.1e-31 109.9 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 EGE03154.1 - 2.7e-08 34.0 0.0 1.3e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE03154.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Cyclase PF04199.13 EGE03156.1 - 1.4e-14 54.5 0.0 3.3e-14 53.3 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase PEP_mutase PF13714.6 EGE03157.1 - 2.7e-65 220.2 0.0 3.3e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MinE PF03776.14 EGE03157.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE MFS_1 PF07690.16 EGE03158.1 - 6.4e-33 114.1 27.6 1e-31 110.2 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.13 EGE03158.1 - 1.5 8.2 4.8 0.48 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DHDPS PF00701.22 EGE03159.1 - 8.3e-35 119.9 0.0 5.9e-34 117.1 0.0 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-HC2 PF13490.6 EGE03159.1 - 0.21 11.9 0.2 0.66 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative zinc-finger Ribonuc_L-PSP PF01042.21 EGE03160.1 - 5.7e-39 132.9 0.1 6.3e-39 132.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP QRPTase_C PF01729.19 EGE03160.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain D-ser_dehydrat PF14031.6 EGE03161.1 - 1.2e-24 86.8 0.0 2.5e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGE03161.1 - 2.2e-13 50.4 0.0 3.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain BST2 PF16716.5 EGE03162.1 - 0.068 13.8 0.4 0.17 12.5 0.4 1.6 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 LSM PF01423.22 EGE03163.1 - 6.1e-17 61.1 0.1 8e-17 60.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain WH2 PF02205.20 EGE03164.1 - 2.4e-09 36.7 0.2 2.4e-09 36.7 0.2 1.9 2 0 0 2 2 2 1 WH2 motif KI67R PF08065.12 EGE03165.1 - 0.052 14.1 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 KI67R (NUC007) repeat DUF3593 PF12159.8 EGE03165.1 - 0.12 12.4 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Ribosomal_L1 PF00687.21 EGE03166.1 - 3.5e-47 160.8 0.2 3.9e-47 160.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 EGE03166.1 - 0.08 13.0 0.5 0.73 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function Acetyltransf_1 PF00583.25 EGE03167.1 - 1.1e-11 44.9 0.0 1.7e-11 44.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE03167.1 - 4.3e-08 33.1 0.0 3.1e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE03167.1 - 5.2e-08 33.2 0.0 7.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE03167.1 - 2.2e-06 27.6 0.0 1.7e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EGE03167.1 - 0.00079 20.1 0.0 0.0012 19.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGE03167.1 - 0.011 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGE03167.1 - 0.046 13.9 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE03167.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Arf PF00025.21 EGE03168.1 - 2.9e-79 264.6 0.1 3.3e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGE03168.1 - 8.2e-15 54.7 0.0 1e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGE03168.1 - 2e-14 53.8 0.1 2.7e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGE03168.1 - 3.3e-13 49.6 1.7 2.1e-09 37.0 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGE03168.1 - 3.6e-13 49.4 0.0 4e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGE03168.1 - 1.8e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGE03168.1 - 3.3e-06 27.1 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGE03168.1 - 0.0079 15.5 0.5 0.021 14.2 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 EGE03168.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Tachylectin PF14517.6 EGE03168.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Tachylectin Mucin15 PF15672.5 EGE03172.1 - 0.0032 17.0 4.0 0.0032 17.0 4.0 2.2 2 1 0 2 2 2 1 Cell-membrane associated Mucin15 SARAF PF06682.12 EGE03172.1 - 0.022 14.4 0.5 0.034 13.8 0.5 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3405 PF11885.8 EGE03173.1 - 6.6e-231 767.4 0.7 8e-231 767.1 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Sod_Cu PF00080.20 EGE03175.1 - 4.6e-09 36.6 0.0 7.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Voldacs PF03517.13 EGE03176.1 - 0.15 12.2 7.6 0.21 11.7 7.6 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF3050 PF11251.8 EGE03176.1 - 0.16 11.6 2.2 3.4 7.2 0.4 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3050) Choline_kinase PF01633.20 EGE03177.1 - 8.5e-45 152.9 0.0 1.1e-43 149.3 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGE03177.1 - 6.2e-08 32.9 0.5 1.8e-07 31.4 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family CHORD PF04968.12 EGE03178.1 - 1.8e-50 169.5 20.4 9.8e-26 90.3 7.1 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGE03178.1 - 3.4e-13 50.4 0.1 5.1e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EGE03178.1 - 0.26 11.1 8.9 3.2 7.6 0.3 3.2 3 0 0 3 3 3 0 BTK motif DUF836 PF05768.14 EGE03179.1 - 5.6e-14 52.3 0.0 6.5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EGE03179.1 - 0.007 16.6 0.0 0.0096 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.14 EGE03180.1 - 1.3e-32 112.8 0.0 1.7e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 EGE03180.1 - 0.015 14.8 0.2 0.96 8.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Phage_TAC_10 PF10963.8 EGE03180.1 - 0.084 13.1 0.1 0.45 10.7 0.1 2.0 1 1 0 1 1 1 0 Phage tail assembly chaperone Fungal_trans PF04082.18 EGE03181.1 - 1.1e-13 50.8 0.2 1.9e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE03181.1 - 0.031 14.4 2.3 0.059 13.5 2.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EGE03182.1 - 2.4e-33 115.4 0.5 3.4e-33 115.0 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGE03182.1 - 5e-22 77.9 0.0 8.3e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGE03182.1 - 2.7e-13 50.6 0.1 1.1e-12 48.6 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGE03182.1 - 5e-05 23.6 0.0 7.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain 14-3-3 PF00244.20 EGE03183.1 - 3.3e-08 33.3 0.1 5.2e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 14-3-3 protein tRNA-synt_1b PF00579.25 EGE03184.1 - 3.7e-23 82.3 0.0 7.3e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) APH PF01636.23 EGE03185.1 - 6.8e-15 55.6 0.3 1.2e-14 54.8 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGE03185.1 - 0.0092 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase SRP72 PF08492.12 EGE03186.1 - 0.11 12.9 9.7 0.18 12.3 6.3 2.7 2 0 0 2 2 2 0 SRP72 RNA-binding domain Lant_dehydr_C PF14028.6 EGE03186.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DUF3237 PF11578.8 EGE03187.1 - 1.8e-38 131.7 0.0 2.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MAP17 PF15807.5 EGE03188.1 - 0.00063 20.0 0.0 0.0012 19.0 0.0 1.4 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GRP PF07172.11 EGE03188.1 - 0.00071 20.2 8.7 0.001 19.7 8.7 1.2 1 0 0 1 1 1 1 Glycine rich protein family PSI PF01437.25 EGE03188.1 - 0.00093 19.7 7.6 0.0018 18.8 7.6 1.5 1 0 0 1 1 1 1 Plexin repeat SARAF PF06682.12 EGE03188.1 - 0.0018 18.0 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TNFR_16_TM PF18422.1 EGE03188.1 - 0.02 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TM231 PF10149.9 EGE03188.1 - 0.2 10.9 0.1 0.29 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 EphA2_TM PF14575.6 EGE03188.1 - 0.22 12.4 0.0 0.31 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PSI_integrin PF17205.3 EGE03188.1 - 0.4 10.5 9.8 0.82 9.5 9.8 1.4 1 0 0 1 1 1 0 Integrin plexin domain FeoB_associated PF12669.7 EGE03188.1 - 0.46 10.9 0.0 0.46 10.9 0.0 2.5 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein EMP24_GP25L PF01105.24 EGE03189.1 - 2e-46 158.2 0.1 2.4e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Vac_ImportDeg PF09783.9 EGE03189.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein DUF1408 PF07193.11 EGE03189.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Myb_DNA-bind_6 PF13921.6 EGE03190.1 - 0.00081 19.6 1.4 0.009 16.2 0.7 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGE03190.1 - 0.028 14.7 2.0 0.063 13.6 1.1 2.2 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-binding PF00249.31 EGE03190.1 - 0.056 13.6 3.3 0.94 9.7 1.8 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain GcrA PF07750.11 EGE03190.1 - 0.26 11.7 4.1 0.22 11.9 0.6 2.4 2 1 0 2 2 2 0 GcrA cell cycle regulator Totivirus_coat PF05518.11 EGE03190.1 - 0.71 7.9 4.7 0.91 7.5 4.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein FGF-BP1 PF06473.12 EGE03190.1 - 1.1 9.1 9.8 0.068 13.0 2.9 2.0 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) PRIMA1 PF16101.5 EGE03190.1 - 4.5 7.3 11.6 3.8 7.6 6.5 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Glyco_hydro_17 PF00332.18 EGE03191.1 - 6.6e-32 111.3 0.0 5.5e-31 108.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF2508 PF10704.9 EGE03192.1 - 0.023 14.9 0.5 0.023 14.9 0.5 4.3 6 0 0 6 6 6 0 Protein of unknown function (DUF2508) PAM2 PF07145.15 EGE03192.1 - 0.8 9.5 10.4 12 5.8 0.1 4.3 4 0 0 4 4 4 0 Ataxin-2 C-terminal region DUF3425 PF11905.8 EGE03193.1 - 1.2e-10 41.4 0.1 2.4e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EGE03193.1 - 0.0041 17.2 17.2 0.069 13.3 17.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor PRKG1_interact PF15898.5 EGE03193.1 - 0.0079 17.1 7.4 0.011 16.6 7.4 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EGE03193.1 - 0.022 15.2 3.5 0.033 14.6 3.0 1.5 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EGE03193.1 - 0.062 13.1 0.9 0.12 12.2 0.6 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF3696 PF12476.8 EGE03193.1 - 0.1 13.0 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF2937 PF11157.8 EGE03193.1 - 0.35 10.6 1.2 0.55 9.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF5094 PF17015.5 EGE03193.1 - 0.57 10.3 3.1 0.82 9.7 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMEM192 PF14802.6 EGE03193.1 - 0.62 9.1 2.4 0.84 8.7 2.4 1.2 1 0 0 1 1 1 0 TMEM192 family GBP_C PF02841.14 EGE03193.1 - 0.69 9.3 5.3 0.95 8.8 5.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GLE1 PF07817.13 EGE03194.1 - 2.2e-47 161.4 0.0 2.2e-47 161.4 0.0 1.5 2 0 0 2 2 2 1 GLE1-like protein AF-4 PF05110.13 EGE03194.1 - 1.8 6.6 33.9 2.3 6.2 33.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4045 PF13254.6 EGE03194.1 - 7.5 6.1 33.5 11 5.6 33.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RNB PF00773.19 EGE03195.1 - 2.1e-77 260.6 0.0 6.8e-77 259.0 0.0 1.8 2 0 0 2 2 2 1 RNB domain Dis3l2_C_term PF17877.1 EGE03195.1 - 2.1e-25 88.9 0.0 6.8e-25 87.2 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EGE03195.1 - 1.4e-24 85.9 0.0 3.2e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EGE03195.1 - 0.00058 20.0 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 2 Cold shock domain DUF4667 PF15700.5 EGE03195.1 - 0.00071 19.8 3.9 0.00071 19.8 3.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4667) Rrp44_CSD1 PF17216.3 EGE03195.1 - 0.0014 18.3 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain TFIIA PF03153.13 EGE03195.1 - 0.0056 16.7 15.1 0.0056 16.7 15.1 3.3 2 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 EGE03196.1 - 3.1e-36 124.1 0.0 5.5e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE03196.1 - 0.0034 17.1 0.2 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic E2 family B MMgT PF10270.9 EGE03198.1 - 6.8e-33 113.0 0.0 8.2e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 EGE03199.1 - 1e-31 108.9 0.8 1e-31 108.9 0.8 1.5 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EGE03199.1 - 5.8e-07 29.8 1.7 5.8e-07 29.8 1.7 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region DUF4604 PF15377.6 EGE03199.1 - 0.04 14.3 1.0 0.055 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GST_C PF00043.25 EGE03199.1 - 0.079 13.2 0.1 0.27 11.5 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 EGE03200.1 - 4.8e-46 157.0 0.0 1.8e-44 151.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGE03200.1 - 2.8e-35 120.3 1.8 2.8e-35 120.3 1.8 2.5 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGE03200.1 - 8.1e-27 93.1 0.1 3.2e-26 91.2 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGE03200.1 - 1.9e-17 63.9 0.0 8.4e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGE03200.1 - 1.5e-12 47.7 0.1 1.7e-07 31.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGE03200.1 - 2.8e-08 34.3 10.0 0.00019 21.9 0.1 4.3 3 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EGE03200.1 - 4.6e-08 32.9 0.3 0.00022 21.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EGE03200.1 - 1.6e-06 28.4 2.8 0.022 15.0 0.0 3.8 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EGE03200.1 - 7.4e-06 25.8 0.0 0.058 13.1 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 EGE03200.1 - 3.3e-05 23.4 0.1 0.029 13.8 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 EGE03200.1 - 3.9e-05 23.3 0.0 0.067 12.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EGE03200.1 - 4.8e-05 23.4 0.2 0.17 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EGE03200.1 - 6.9e-05 22.8 0.3 0.2 11.6 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_28 PF13521.6 EGE03200.1 - 0.00016 21.9 1.5 0.032 14.5 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_18 PF13238.6 EGE03200.1 - 0.00037 21.1 0.1 1.5 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGE03200.1 - 0.00056 19.9 5.6 0.96 9.3 0.1 4.2 3 2 0 3 3 3 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 EGE03200.1 - 0.00098 18.8 0.1 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGE03200.1 - 0.0011 18.7 0.0 0.64 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGE03200.1 - 0.0035 16.8 0.2 1.9 7.8 0.1 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EGE03200.1 - 0.0045 17.0 0.0 7.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EGE03200.1 - 0.0046 17.3 0.1 2 8.8 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 EGE03200.1 - 0.0054 17.1 0.9 0.17 12.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGE03200.1 - 0.0088 16.6 1.0 0.68 10.4 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 EGE03200.1 - 0.0097 16.1 0.1 3.9 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGE03200.1 - 0.01 15.4 0.3 0.19 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGE03200.1 - 0.012 15.5 1.1 1.5 8.7 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase PduV-EutP PF10662.9 EGE03200.1 - 0.012 15.3 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGE03200.1 - 0.015 15.3 1.2 6.4 6.8 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EGE03200.1 - 0.016 14.1 0.1 0.49 9.3 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EGE03200.1 - 0.019 14.3 0.0 1.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 EGE03200.1 - 0.02 15.1 0.1 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EGE03200.1 - 0.02 14.0 0.3 0.68 9.0 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) UvrD-helicase PF00580.21 EGE03200.1 - 0.035 13.6 2.3 0.42 10.1 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain FapA PF03961.13 EGE03200.1 - 0.047 12.3 3.3 0.083 11.5 3.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_21 PF13304.6 EGE03200.1 - 0.074 12.9 0.2 1.1 9.0 0.0 2.9 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP_bind_1 PF03029.17 EGE03200.1 - 0.11 12.2 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGE03200.1 - 0.2 11.4 8.1 0.17 11.6 0.4 3.7 4 1 0 4 4 4 0 AAA domain HisKA_2 PF07568.12 EGE03200.1 - 0.24 11.5 1.4 0.78 9.9 0.8 2.2 2 0 0 2 2 1 0 Histidine kinase DUF4094 PF13334.6 EGE03200.1 - 0.34 11.4 2.3 0.72 10.3 0.6 2.5 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.19 EGE03200.1 - 0.77 7.6 3.0 1.1 7.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_V PF00488.21 EGE03201.1 - 8.9e-42 143.2 0.0 1.7e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE03201.1 - 2.8e-18 66.8 0.0 1e-17 65.0 0.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGE03201.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV Beta_propel PF09826.9 EGE03201.1 - 0.035 12.9 0.2 0.057 12.3 0.2 1.2 1 0 0 1 1 1 0 Beta propeller domain AAA PF00004.29 EGE03201.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PPV_E1_C PF00519.17 EGE03201.1 - 0.23 10.2 0.4 0.56 9.0 0.1 1.7 2 0 0 2 2 2 0 Papillomavirus helicase Sas10 PF09368.10 EGE03202.1 - 8.5e-29 99.8 7.6 8.5e-29 99.8 7.6 3.5 4 1 1 5 5 5 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGE03202.1 - 5e-12 46.3 0.1 3e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.25 EGE03203.1 - 2.2e-23 82.8 0.0 3e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE03203.1 - 2.3e-10 40.4 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE03203.1 - 3.1e-10 40.3 0.1 2.7e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGE03203.1 - 0.0064 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EGE03203.1 - 0.0094 15.4 0.0 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGE03203.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EGE03203.1 - 0.026 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGE03203.1 - 0.032 14.3 0.0 0.1 12.6 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGE03203.1 - 0.044 14.0 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FA_hydroxylase PF04116.13 EGE03204.1 - 9.4e-17 61.6 13.8 9.4e-17 61.6 13.8 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 EGE03205.1 - 5.4e-37 126.7 0.6 7.2e-37 126.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 EGE03206.1 - 7.9e-26 90.4 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EGE03206.1 - 2.5e-13 50.2 1.8 1.6e-12 47.6 2.6 1.8 2 0 0 2 2 2 1 UCH-binding domain Ion_trans PF00520.31 EGE03207.1 - 1.9e-125 417.0 87.5 5e-40 137.3 7.6 4.6 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EGE03207.1 - 0.0081 15.9 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EGE03207.1 - 0.009 15.5 0.0 0.037 13.6 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGE03207.1 - 0.026 14.4 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EGE03207.1 - 0.029 14.8 0.0 0.38 11.2 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair FUN14 PF04930.15 EGE03207.1 - 0.063 13.7 0.3 23 5.5 0.0 2.9 2 0 0 2 2 2 0 FUN14 family SET PF00856.28 EGE03210.1 - 1.2e-17 64.8 0.1 3.3e-17 63.4 0.1 1.8 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EGE03210.1 - 7.7e-11 42.6 3.3 7.7e-11 42.6 3.3 2.3 3 0 0 3 3 3 1 Pre-SET motif Nop52 PF05997.12 EGE03211.1 - 4.3e-55 186.9 1.8 6.5e-54 183.0 1.8 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 EGE03211.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair NOT2_3_5 PF04153.18 EGE03211.1 - 0.064 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family UBD PF16455.5 EGE03212.1 - 4.8e-36 123.2 0.0 7.3e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EGE03212.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family baeRF_family2 PF18844.1 EGE03212.1 - 0.0022 18.0 1.6 0.0039 17.3 1.6 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 baeRF_family10 PF18854.1 EGE03212.1 - 0.0041 17.4 0.1 0.0064 16.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Rad60-SLD PF11976.8 EGE03212.1 - 0.0053 16.6 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGE03212.1 - 0.094 13.3 0.1 0.21 12.2 0.0 1.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF1604 PF07713.13 EGE03213.1 - 3.7e-43 145.2 9.9 2.7e-42 142.5 2.3 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EGE03213.1 - 1.7e-07 31.0 1.5 2.8e-07 30.3 0.4 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EGE03213.1 - 0.043 13.9 0.4 0.043 13.9 0.4 3.9 3 1 1 4 4 4 0 G-patch domain SLT_2 PF13406.6 EGE03213.1 - 0.066 12.4 0.1 0.17 11.1 0.1 1.6 1 1 0 1 1 1 0 Transglycosylase SLT domain Pkinase PF00069.25 EGE03214.1 - 4.6e-72 242.5 0.0 7.8e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03214.1 - 3.7e-41 141.1 0.0 9.4e-41 139.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGE03214.1 - 4.3e-17 61.6 0.4 8.1e-17 60.8 0.4 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EGE03214.1 - 1.1e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGE03214.1 - 4.1e-06 26.3 0.1 7.6e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE03214.1 - 7.1e-06 25.5 0.0 0.0001 21.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGE03214.1 - 0.003 17.5 0.2 0.16 11.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 EGE03214.1 - 0.012 15.3 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EGE03214.1 - 0.025 14.2 0.5 0.075 12.6 0.5 1.7 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EGE03214.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DAGK_cat PF00781.24 EGE03215.1 - 2.2e-26 91.9 0.1 3.3e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF2569 PF10754.9 EGE03217.1 - 0.11 13.0 13.0 0.14 12.6 3.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) LrgB PF04172.16 EGE03217.1 - 1.7 8.1 12.5 0.036 13.6 4.1 2.3 2 1 0 2 2 2 0 LrgB-like family Adaptin_N PF01602.20 EGE03218.1 - 3.1e-94 316.4 12.9 6.6e-94 315.3 12.9 1.5 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EGE03218.1 - 1.4e-57 193.5 0.6 3.2e-57 192.4 0.6 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EGE03218.1 - 1.1e-55 187.0 0.0 4.4e-55 185.1 0.0 2.1 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EGE03218.1 - 6.1e-13 49.1 11.2 8.2e-10 39.0 0.0 3.5 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGE03218.1 - 2e-09 37.7 0.4 1.1e-05 25.7 0.0 5.2 5 1 1 6 6 6 3 HEAT repeats HEAT PF02985.22 EGE03218.1 - 0.00098 19.2 1.9 1.7 9.1 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EGE03218.1 - 0.0027 18.2 4.3 0.036 14.6 0.1 4.5 4 0 0 4 4 4 1 HEAT-like repeat AP4E_app_platf PF14807.6 EGE03218.1 - 0.0059 16.9 0.2 0.02 15.2 0.2 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Arm PF00514.23 EGE03218.1 - 0.034 14.2 2.4 16 5.7 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat NBD94 PF16830.5 EGE03218.1 - 0.41 11.1 3.5 7.7 7.0 0.9 2.7 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH DUF1542 PF07564.11 EGE03218.1 - 3 8.0 8.3 0.19 11.9 2.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Mago_nashi PF02792.14 EGE03219.1 - 6.9e-71 236.9 0.3 8.2e-71 236.7 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 EGE03220.1 - 1.5e-49 167.9 0.2 2.1e-49 167.4 0.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF3738 PF12543.8 EGE03220.1 - 0.095 12.8 1.5 0.16 12.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Guanylate_kin PF00625.21 EGE03221.1 - 9.4e-44 149.3 0.0 1.1e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RasGEF_N_2 PF14663.6 EGE03223.1 - 0.13 12.7 0.6 4.3 7.8 0.0 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BLOC1S3 PF15753.5 EGE03223.1 - 1.3 9.2 8.6 1.3 9.1 1.1 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Jnk-SapK_ap_N PF09744.9 EGE03223.1 - 2.7 8.2 0.0 2.7 8.2 0.0 3.6 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 HrpB7 PF09486.10 EGE03223.1 - 2.9 8.3 11.7 1.7 9.1 3.3 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fe-ADH_2 PF13685.6 EGE03224.1 - 0.24 11.1 2.1 0.19 11.4 0.1 1.8 2 1 0 2 2 2 0 Iron-containing alcohol dehydrogenase Syntaxin-6_N PF09177.11 EGE03224.1 - 0.51 10.9 12.0 2.2 8.9 5.1 2.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 EGE03224.1 - 2.2 8.6 16.7 0.97 9.7 1.4 4.4 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.11 EGE03224.1 - 2.5 6.9 13.6 0.31 9.9 5.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Ank_2 PF12796.7 EGE03227.1 - 6.7e-34 116.3 0.5 1e-13 51.6 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE03227.1 - 6.2e-24 84.1 0.5 1.5e-07 31.8 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE03227.1 - 7.8e-20 70.7 0.0 1.5e-08 34.7 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE03227.1 - 6.9e-19 66.0 2.5 0.013 16.0 0.0 8.4 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 EGE03227.1 - 2e-15 56.5 1.3 0.017 15.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Aa_trans PF01490.18 EGE03228.1 - 6.8e-26 90.9 36.4 1.4e-25 89.9 36.4 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3040 PF11239.8 EGE03228.1 - 2.6 8.4 0.0 2.6 8.4 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) S1FA PF04689.13 EGE03228.1 - 4.4 7.5 5.3 1 9.6 0.7 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA DUF973 PF06157.11 EGE03228.1 - 4.5 6.2 13.4 2.3 7.2 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF973) GCV_T PF01571.21 EGE03229.1 - 6.9e-78 261.6 0.0 9.6e-78 261.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGE03229.1 - 2.7e-17 62.5 0.5 1.2e-16 60.4 0.3 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.20 EGE03230.1 - 1.1e-51 174.9 0.0 1.8e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 EGE03230.1 - 9.4e-07 29.4 0.1 6.2e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGE03230.1 - 0.00031 20.9 2.6 0.00054 20.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGE03230.1 - 0.002 17.8 0.6 0.0052 16.5 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGE03230.1 - 0.016 14.5 1.2 0.04 13.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGE03230.1 - 0.045 14.3 2.0 0.071 13.6 0.0 2.3 3 1 0 3 3 3 0 ABC transporter CbiA PF01656.23 EGE03230.1 - 0.07 13.2 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 EGE03230.1 - 0.18 12.2 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGE03230.1 - 0.56 10.6 7.5 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGE03230.1 - 2.2 8.7 4.6 11 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain V-ATPase_C PF03223.15 EGE03231.1 - 5.6e-123 411.0 0.0 6.5e-123 410.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EGE03231.1 - 0.039 14.6 0.0 0.091 13.4 0.0 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain 4HBT PF03061.22 EGE03232.1 - 1e-10 41.8 0.0 1.7e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.19 EGE03233.1 - 6.4e-36 123.5 2.5 4.5e-18 65.5 0.1 2.3 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EGE03233.1 - 2.5e-15 56.9 0.6 7.5e-15 55.4 0.1 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EGE03233.1 - 5.2e-12 45.8 0.4 7.3e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGE03233.1 - 0.018 15.6 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain Citrate_bind PF16114.5 EGE03233.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding Nucleo_P87 PF07267.11 EGE03234.1 - 0.52 9.1 11.0 0.59 8.9 11.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMEM171 PF15471.6 EGE03234.1 - 1.2 8.0 4.3 1.6 7.6 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Peptidase_S64 PF08192.11 EGE03234.1 - 4.3 5.7 10.2 4.8 5.5 10.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 EGE03234.1 - 8.9 3.3 10.0 11 3.0 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer E1-E2_ATPase PF00122.20 EGE03235.1 - 1.3e-34 119.3 4.1 1.3e-34 119.3 4.1 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGE03235.1 - 5.4e-24 84.1 0.0 1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE03235.1 - 6.4e-16 59.3 1.5 5.1e-15 56.3 1.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE03235.1 - 2.7e-06 27.0 0.2 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 EGE03235.1 - 2.3e-05 24.2 1.3 2.3e-05 24.2 1.3 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EGE03235.1 - 3.1e-05 23.9 0.6 8.5e-05 22.4 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RskA PF10099.9 EGE03235.1 - 0.0017 18.7 0.8 2 8.7 0.0 3.7 2 1 0 2 2 2 1 Anti-sigma-K factor rskA DUF1774 PF08611.10 EGE03235.1 - 0.028 14.7 0.4 0.12 12.7 0.4 2.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1774) BatA PF07584.11 EGE03235.1 - 0.25 11.7 1.4 4 7.9 0.1 3.0 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal LptF_LptG PF03739.14 EGE03235.1 - 1.5 7.6 11.5 0.082 11.7 6.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Nup84_Nup100 PF04121.13 EGE03237.1 - 8.4e-148 493.6 7.4 1.1e-97 327.9 3.8 2.1 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 HBM PF16591.5 EGE03237.1 - 0.0097 15.4 0.8 0.0097 15.4 0.8 1.9 2 0 0 2 2 2 1 Helical bimodular sensor domain PEP-utilizers_C PF02896.18 EGE03237.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain MTCP1 PF08991.10 EGE03238.1 - 4.6e-27 94.0 11.7 5.2e-27 93.9 11.7 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EGE03238.1 - 0.021 15.0 6.5 0.034 14.3 6.5 1.4 1 0 0 1 1 1 0 CHCH domain Rad60-SLD PF11976.8 EGE03239.1 - 5.8e-21 74.1 0.2 6.7e-21 73.9 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGE03239.1 - 7.2e-12 44.9 0.1 8.1e-12 44.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Abhydrolase_6 PF12697.7 EGE03241.1 - 5e-08 33.8 0.0 6.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.21 EGE03241.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Methyltransf_25 PF13649.6 EGE03242.1 - 1.8e-10 41.4 0.0 6.2e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03242.1 - 4.1e-06 27.4 0.0 1.2e-05 25.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE03242.1 - 6.7e-05 22.8 0.0 9.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE03242.1 - 7.6e-05 23.4 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE03242.1 - 0.0005 19.9 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE03242.1 - 0.064 12.6 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Isochorismatase PF00857.20 EGE03243.1 - 3.5e-34 118.5 0.1 1.1e-33 116.8 0.1 1.8 2 0 0 2 2 2 1 Isochorismatase family Iso_dh PF00180.20 EGE03243.1 - 1.6e-13 50.5 0.0 1.4e-07 31.1 0.0 2.4 2 1 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase TK PF00265.18 EGE03243.1 - 0.0081 16.0 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 1 Thymidine kinase Methyltransf_31 PF13847.6 EGE03244.1 - 2.5e-10 40.3 0.0 3.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03244.1 - 1.1e-09 38.9 0.0 2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE03244.1 - 4.1e-08 33.2 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE03244.1 - 5e-08 33.6 0.0 9.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03244.1 - 5.3e-05 23.8 0.0 0.0001 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE03244.1 - 0.032 13.5 0.0 0.075 12.4 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CheR PF01739.18 EGE03244.1 - 0.045 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DUF2236 PF09995.9 EGE03245.1 - 4.8e-06 26.9 0.2 7e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.8 EGE03245.1 - 0.062 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Aldedh PF00171.22 EGE03246.1 - 2e-107 359.6 0.0 2.5e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.25 EGE03247.1 - 1e-68 231.4 0.0 2.2e-68 230.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGE03247.1 - 1.3e-43 148.2 0.1 2.1e-43 147.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGE03247.1 - 2.1e-05 24.8 0.0 5.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGE03247.1 - 0.00085 18.6 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EGE03247.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 EGE03248.1 - 1.3e-06 28.1 0.0 9.6e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.10 EGE03248.1 - 0.078 13.0 1.1 0.29 11.2 0.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Porph_ging PF09697.10 EGE03248.1 - 0.36 11.4 2.6 0.46 11.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Pkinase PF00069.25 EGE03249.1 - 2.4e-66 223.8 0.0 3.9e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03249.1 - 8.3e-35 120.3 0.0 7.9e-34 117.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE03249.1 - 2e-06 26.9 0.1 4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGE03249.1 - 2.6e-06 27.0 0.1 1.8e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGE03249.1 - 1.2e-05 25.4 0.0 0.004 17.1 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGE03249.1 - 0.0079 15.3 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGE03249.1 - 0.048 13.0 0.8 0.46 9.8 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGE03249.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGE03249.1 - 0.15 11.6 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 RIO1 family Chromo PF00385.24 EGE03252.1 - 5.1e-08 32.7 0.2 1.3e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 EGE03252.1 - 0.00013 22.2 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3653 PF12375.8 EGE03252.1 - 0.03 14.4 0.6 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Phage protein DUF4529 PF15032.6 EGE03253.1 - 0.094 11.8 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) Goodbye PF17109.5 EGE03254.1 - 1.1e-29 103.4 0.3 4.8e-29 101.3 0.3 2.3 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_6 PF13174.6 EGE03254.1 - 0.044 14.4 0.8 5.1 8.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PP1_inhibitor PF05361.12 EGE03254.1 - 3.2 7.8 9.3 19 5.2 5.8 3.7 3 1 0 3 3 3 0 PKC-activated protein phosphatase-1 inhibitor SesA PF17107.5 EGE03255.1 - 3.6e-05 23.9 0.0 0.026 14.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases VIT PF08487.10 EGE03256.1 - 1.4e-30 105.8 0.0 6.1e-30 103.7 0.1 2.1 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGE03256.1 - 7.6e-25 87.7 0.0 1.4e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGE03256.1 - 1.5e-06 27.9 0.0 4.4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EGE03256.1 - 3.1e-06 27.5 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGE03256.1 - 0.0017 19.0 0.0 0.0039 17.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGE03256.1 - 0.0094 15.4 0.0 0.0094 15.4 0.0 1.9 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein DUF2201 PF09967.9 EGE03256.1 - 0.11 12.7 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 VWA-like domain (DUF2201) LANC_like PF05147.13 EGE03257.1 - 8.8e-22 77.2 0.0 1.6e-19 69.7 0.0 2.3 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein Haem_oxygenas_2 PF14518.6 EGE03257.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme CBF PF03914.17 EGE03258.1 - 5.1e-53 179.6 0.2 5.1e-53 179.6 0.2 2.9 4 0 0 4 4 4 1 CBF/Mak21 family Prok-E2_C PF14459.6 EGE03258.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C Cnd1 PF12717.7 EGE03258.1 - 0.1 12.6 0.3 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 tRNA-synt_2b PF00587.25 EGE03259.1 - 8.8e-30 104.0 0.0 3.3e-29 102.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGE03259.1 - 3.5e-09 36.7 0.0 9.2e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain zf-ribbon_3 PF13248.6 EGE03259.1 - 0.072 12.5 0.4 0.072 12.5 0.4 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Prefoldin PF02996.17 EGE03260.1 - 8.6e-23 80.5 0.1 1.1e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit KH_1 PF00013.29 EGE03261.1 - 0.0045 16.8 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 2 KH domain CHCH PF06747.13 EGE03262.1 - 2.4e-06 27.5 11.6 6.4e-05 23.0 5.7 2.4 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 EGE03262.1 - 0.036 14.1 8.1 2.7 8.1 0.0 3.0 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EGE03262.1 - 0.16 12.0 7.7 1 9.4 4.5 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EGE03262.1 - 1.1 9.0 5.5 7.8 6.3 1.6 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Thioredox_DsbH PF03190.15 EGE03263.1 - 5.8e-70 234.5 0.0 1.4e-69 233.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EGE03263.1 - 2.9e-06 27.4 0.0 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like DUF2384 PF09722.10 EGE03263.1 - 0.11 12.5 0.0 6.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) WD40 PF00400.32 EGE03264.1 - 1.6e-12 47.7 16.2 0.0078 17.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03264.1 - 0.01 16.1 0.1 6.8 7.1 0.0 3.5 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EGE03264.1 - 0.025 13.7 0.1 0.22 10.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 EGE03264.1 - 0.068 11.9 0.1 0.22 10.3 0.0 1.8 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EGE03264.1 - 0.091 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 LSM14 PF12701.7 EGE03265.1 - 3.4e-26 91.2 0.0 6e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EGE03265.1 - 1.6e-18 67.5 2.6 1.6e-18 67.5 2.6 3.0 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.6 EGE03265.1 - 0.00026 21.1 0.1 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain TFIIA PF03153.13 EGE03265.1 - 1 9.3 41.3 0.062 13.3 31.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ACBP PF00887.19 EGE03266.1 - 2.5e-22 78.9 0.0 2.5e-22 78.9 0.0 2.4 2 1 0 2 2 2 1 Acyl CoA binding protein DNA_repr_REX1B PF14966.6 EGE03266.1 - 0.1 13.3 0.4 0.23 12.2 0.4 1.5 1 0 0 1 1 1 0 DNA repair REX1-B Sporozoite_P67 PF05642.11 EGE03266.1 - 0.1 10.6 2.1 0.13 10.3 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraP PF07296.11 EGE03266.1 - 0.25 10.5 0.9 0.39 9.9 0.9 1.3 1 0 0 1 1 1 0 TraP protein PilJ PF13675.6 EGE03266.1 - 0.4 10.7 3.4 1.2 9.2 1.8 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DNA_pol_phi PF04931.13 EGE03266.1 - 1.9 6.5 6.8 3.2 5.7 6.7 1.4 2 0 0 2 2 2 0 DNA polymerase phi DUF1754 PF08555.10 EGE03266.1 - 2 9.3 10.2 3 8.7 7.2 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.6 EGE03266.1 - 2.4 7.8 5.3 5.2 6.7 5.3 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EGE03266.1 - 3.6 6.8 7.9 5.5 6.2 7.9 1.2 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_15 PF01793.16 EGE03267.1 - 8.5e-116 386.7 7.7 1e-115 386.5 7.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 EGE03268.1 - 1.6e-29 103.6 2.3 2e-29 103.2 0.6 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGE03268.1 - 6.8e-24 84.9 1.6 6.8e-24 84.9 1.6 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EGE03268.1 - 9e-05 21.0 1.4 0.00022 19.7 0.5 2.0 2 1 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GATase_5 PF13507.6 EGE03269.1 - 2.7e-97 325.0 0.0 4.3e-97 324.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGE03269.1 - 4.4e-39 134.1 0.7 1.1e-24 87.4 0.2 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGE03269.1 - 4.2e-32 110.5 0.0 7.5e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGE03269.1 - 3.6e-21 75.4 0.0 8.7e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EGE03269.1 - 0.1 13.3 0.7 0.85 10.3 0.0 2.7 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain MFS_1 PF07690.16 EGE03270.1 - 1.5e-44 152.4 28.9 1.5e-44 152.4 28.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE03270.1 - 1.3e-07 30.9 27.8 3.1e-07 29.6 27.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGE03270.1 - 1.2e-06 27.3 3.3 2e-06 26.5 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGE03270.1 - 1.8e-05 24.2 0.9 1.8e-05 24.2 0.9 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4271 PF14093.6 EGE03270.1 - 0.065 13.1 0.1 0.065 13.1 0.1 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4271) DUF4064 PF13273.6 EGE03270.1 - 7.8 6.8 11.5 3.1 8.1 0.1 4.5 4 2 0 4 4 4 0 Protein of unknown function (DUF4064) zf-C3H1 PF10650.9 EGE03271.1 - 1.1e-09 37.8 1.0 1.9e-09 37.0 1.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.21 EGE03272.1 - 1.5e-264 879.3 1.5 1.8e-264 879.1 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EGE03272.1 - 1.5e-15 56.2 269.6 1.1e-09 36.8 119.4 6.9 2 2 1 3 3 3 2 Myosin tail Myosin_N PF02736.19 EGE03272.1 - 7.8e-11 41.6 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.8 EGE03272.1 - 0.00068 19.7 12.0 0.00068 19.7 12.0 17.7 4 3 13 19 19 19 3 Afadin- and alpha -actinin-Binding DUF1292 PF06949.11 EGE03272.1 - 0.04 14.9 0.1 0.2 12.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1292) AAA_22 PF13401.6 EGE03272.1 - 0.51 10.6 0.0 0.51 10.6 0.0 5.4 4 2 2 6 6 6 0 AAA domain Isy1 PF06246.12 EGE03273.1 - 1.4e-87 293.5 0.1 1.6e-87 293.3 0.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family MMR_HSR1 PF01926.23 EGE03274.1 - 2.2e-12 47.1 0.0 4.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE03274.1 - 4.1e-07 30.1 0.0 9e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EGE03274.1 - 0.00065 19.3 0.3 0.0016 18.0 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EGE03274.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGE03274.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EGE03274.1 - 0.044 13.0 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 EGE03274.1 - 0.06 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EGE03274.1 - 0.1 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 EGE03274.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 EGE03274.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NTPase Septin PF00735.18 EGE03274.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Septin Roc PF08477.13 EGE03274.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HCO3_cotransp PF00955.21 EGE03275.1 - 5.9e-67 226.6 14.4 1.5e-38 132.9 0.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family PI3Ka PF00613.20 EGE03276.1 - 7.8e-59 198.2 0.1 1.2e-58 197.5 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGE03276.1 - 9.9e-46 156.6 0.0 1.4e-30 107.0 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGE03276.1 - 1.9e-32 112.1 0.0 3.2e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EGE03277.1 - 1.2e-31 108.8 0.0 3.5e-31 107.3 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGE03277.1 - 7.8e-16 57.9 0.1 2.3e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.6 EGE03278.1 - 3.2e-18 66.0 0.1 3.8e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.23 EGE03279.1 - 3.5e-17 62.8 7.7 4.6e-17 62.4 7.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EGE03279.1 - 0.0054 16.3 2.1 0.011 15.3 2.2 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein PepSY_TM PF03929.16 EGE03279.1 - 4.7 6.8 9.0 0.14 11.8 0.8 1.9 1 1 1 2 2 2 0 PepSY-associated TM region Metallophos PF00149.28 EGE03280.1 - 8.7e-14 52.5 0.0 1.4e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE03280.1 - 2.7e-07 30.9 0.0 8.1e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGE03280.1 - 0.046 13.0 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily ThiF PF00899.21 EGE03281.1 - 2.9e-41 141.4 0.0 4.7e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGE03281.1 - 0.0015 18.8 1.7 0.028 14.7 1.7 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGE03281.1 - 0.0053 17.0 0.1 0.016 15.5 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EGE03281.1 - 0.058 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EGE03281.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ehbp PF10622.9 EGE03281.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Energy-converting hydrogenase B subunit P (EhbP) Melibiase_2 PF16499.5 EGE03281.1 - 0.12 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha galactosidase A Abhydrolase_1 PF00561.20 EGE03282.1 - 5.2e-44 150.8 0.1 7.5e-44 150.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGE03282.1 - 0.00044 20.0 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Gly_transf_sug PF04488.15 EGE03284.1 - 1.6e-14 54.3 0.0 3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Trypan_PARP PF05887.11 EGE03284.1 - 0.0024 17.9 8.9 0.0039 17.2 8.9 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 EGE03285.1 - 7.1e-63 212.4 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03285.1 - 3.7e-34 118.2 0.0 5.1e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE03285.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PyrBI_leader PF08052.11 EGE03285.1 - 0.0087 16.0 0.1 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 PyrBI operon leader peptide Haspin_kinase PF12330.8 EGE03285.1 - 0.015 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGE03285.1 - 0.015 15.2 0.0 0.054 13.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE03285.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2773 PF10971.8 EGE03285.1 - 0.031 14.4 0.1 0.099 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2773) ATP-synt_C PF00137.21 EGE03286.1 - 8.4e-29 99.7 36.0 6.5e-18 64.8 14.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 EGE03287.1 - 4.4e-81 272.5 0.0 3e-80 269.8 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EGE03287.1 - 1.5e-39 135.2 0.0 3.3e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EGE03287.1 - 9e-38 130.3 0.0 1.6e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EGE03287.1 - 3.9e-13 49.3 0.0 8.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.18 EGE03288.1 - 3.9e-108 361.0 0.3 6.3e-108 360.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGE03288.1 - 9.7e-06 25.7 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGE03288.1 - 0.0011 19.0 4.0 1 9.4 0.0 3.2 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGE03288.1 - 0.0029 17.2 0.2 0.17 11.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE03288.1 - 0.0079 16.1 0.5 0.0079 16.1 0.5 2.5 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EGE03288.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 AIG1 family IIGP PF05049.13 EGE03288.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EGE03288.1 - 0.18 12.3 1.3 0.96 10.0 0.0 2.5 2 1 0 2 2 2 0 ABC transporter EB1 PF03271.17 EGE03288.1 - 0.33 11.2 4.3 3.5 8.0 1.3 2.8 2 0 0 2 2 2 0 EB1-like C-terminal motif WD40 PF00400.32 EGE03289.1 - 0.00012 22.8 0.0 0.93 10.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03289.1 - 0.0011 19.2 0.0 0.43 10.9 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE03289.1 - 0.021 13.8 0.1 0.14 11.1 0.1 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGE03289.1 - 0.047 13.0 0.0 0.29 10.4 0.0 1.9 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 EGE03290.1 - 1.2e-19 69.9 0.1 4.6e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE03290.1 - 1.4e-05 25.2 0.0 4.6e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGE03290.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EGE03290.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Ribonuclease B OB domain DLIC PF05783.11 EGE03291.1 - 5.4e-31 107.9 2.1 4.1e-27 95.2 0.0 3.9 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) Urb2 PF10441.9 EGE03291.1 - 0.2 11.6 0.0 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Urb2/Npa2 family Peptidase_S9 PF00326.21 EGE03292.1 - 3e-50 170.6 0.2 8.4e-50 169.2 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PD40 PF07676.12 EGE03292.1 - 5.3e-11 42.2 1.2 0.0051 16.7 0.0 4.9 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 EGE03292.1 - 0.02 13.7 0.0 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3748 PF12566.8 EGE03292.1 - 0.092 12.7 0.0 1.5 8.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3748) Peptidase_C12 PF01088.21 EGE03294.1 - 3.2e-51 174.1 0.0 3.8e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Y_phosphatase3 PF13350.6 EGE03295.1 - 2.4e-25 89.9 0.0 2.7e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Lysis_col PF02402.16 EGE03295.1 - 0.0098 15.6 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 Lysis protein DUF2052 PF09747.9 EGE03297.1 - 7.7e-11 42.5 0.1 8.8e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Response_reg PF00072.24 EGE03298.1 - 2.6e-21 75.9 0.0 2.2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain SH3_1 PF00018.28 EGE03299.1 - 3e-09 36.4 0.1 5.2e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE03299.1 - 3.6e-07 29.9 0.0 1e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGE03299.1 - 6.7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EGE03299.1 - 0.09 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 SH3 domain YhhN PF07947.14 EGE03299.1 - 0.14 11.7 8.7 0.2 11.3 8.7 1.1 1 0 0 1 1 1 0 YhhN family Dynactin_p22 PF07426.11 EGE03300.1 - 5.4e-07 29.6 0.0 7.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 UBA_4 PF14555.6 EGE03301.1 - 2e-14 53.1 0.2 2.5e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 UBA-like domain AMP-binding PF00501.28 EGE03302.1 - 4.9e-97 325.2 0.0 5.7e-97 325.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE03302.1 - 2.2e-13 51.0 0.3 6.8e-13 49.4 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BUD22 PF09073.10 EGE03304.1 - 0.00061 19.3 6.0 0.00065 19.2 6.0 1.1 1 0 0 1 1 1 1 BUD22 eIF3_subunit PF08597.10 EGE03304.1 - 0.012 15.6 12.8 0.018 14.9 12.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RNA_polI_A34 PF08208.11 EGE03304.1 - 0.015 15.4 8.9 0.019 15.1 8.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.12 EGE03304.1 - 0.018 13.3 9.8 0.02 13.1 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.6 EGE03304.1 - 0.021 15.5 6.3 0.03 15.1 6.3 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Nop53 PF07767.11 EGE03304.1 - 0.028 13.8 14.6 0.037 13.4 14.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) HGTP_anticodon2 PF12745.7 EGE03304.1 - 0.061 12.8 1.0 0.076 12.5 1.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs GCIP PF13324.6 EGE03304.1 - 0.12 12.0 3.3 0.13 11.9 3.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Drc1-Sld2 PF11719.8 EGE03304.1 - 0.13 11.7 8.5 0.16 11.5 8.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein TLP-20 PF06088.11 EGE03304.1 - 0.16 11.9 3.1 0.21 11.5 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) YL1 PF05764.13 EGE03304.1 - 0.2 11.7 14.4 0.27 11.3 14.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sporozoite_P67 PF05642.11 EGE03304.1 - 0.38 8.8 8.7 0.48 8.5 8.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFB6 PF17110.5 EGE03304.1 - 0.43 10.3 6.5 0.63 9.8 6.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Cnd2 PF05786.14 EGE03304.1 - 0.46 9.1 11.4 0.57 8.8 11.4 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 CDC27 PF09507.10 EGE03304.1 - 0.58 9.5 13.3 0.77 9.1 13.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PTPRCAP PF15713.5 EGE03304.1 - 0.68 10.2 11.9 1.3 9.3 11.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3381 PF11861.8 EGE03304.1 - 0.69 9.7 14.1 0.96 9.2 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 EGE03304.1 - 0.71 8.1 12.8 0.88 7.8 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein GEN1_C PF18380.1 EGE03304.1 - 0.74 10.7 9.0 1.1 10.1 9.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain CENP-B_dimeris PF09026.10 EGE03304.1 - 0.79 10.1 14.1 1.2 9.6 14.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 EGE03304.1 - 4.9 6.5 19.7 10 5.5 19.8 1.4 1 1 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 EGE03304.1 - 7 7.1 24.3 18 5.8 24.3 1.7 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRP14 PF15459.6 EGE03305.1 - 5.9 7.6 15.0 11 6.8 15.0 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Pkinase PF00069.25 EGE03306.1 - 7.2e-52 176.4 0.0 9.8e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03306.1 - 2.9e-25 89.0 0.1 2.3e-24 86.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE03306.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGE03306.1 - 0.079 11.7 0.0 0.19 10.4 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGE03306.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bot1p PF12298.8 EGE03308.1 - 1.3e-58 198.0 0.8 1.3e-58 198.0 0.8 1.9 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.22 EGE03309.1 - 1.8e-16 59.7 0.0 3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGE03309.1 - 1.2e-06 29.0 10.3 1.2e-06 29.0 10.3 4.1 4 0 0 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 EGE03310.1 - 2.3e-19 69.4 10.4 3.1e-06 27.8 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03310.1 - 1.4e-07 31.7 0.2 0.15 12.4 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE03310.1 - 0.0039 16.2 0.1 0.95 8.4 0.0 2.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGE03310.1 - 0.0043 15.8 2.0 1.1 7.8 0.1 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.11 EGE03310.1 - 0.014 14.2 0.0 0.83 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) PUL PF08324.11 EGE03311.1 - 1.2e-71 241.2 0.2 1.6e-71 240.8 0.2 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGE03311.1 - 3.6e-44 149.6 0.1 8e-44 148.5 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGE03311.1 - 3.2e-30 103.7 16.8 6.2e-07 30.0 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat YjeF_N PF03853.15 EGE03312.1 - 9.2e-37 126.6 0.0 1.1e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 EGE03312.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ribosomal_S16 PF00886.19 EGE03313.1 - 1.9e-24 85.4 0.1 3.1e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Dickkopf_N PF04706.12 EGE03314.1 - 0.0019 18.6 13.9 0.0019 18.6 13.9 4.6 4 1 0 4 4 4 2 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGE03314.1 - 0.037 14.3 5.1 0.037 14.3 5.1 5.1 1 1 2 4 4 4 0 EB module YbgS PF13985.6 EGE03314.1 - 5.3 7.3 9.9 0.33 11.2 0.4 2.5 1 1 0 2 2 2 0 YbgS-like protein RRM_1 PF00076.22 EGE03316.1 - 2.8e-17 62.3 0.0 1.7e-13 50.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE03316.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif CH PF00307.31 EGE03317.1 - 2.5e-48 162.8 0.2 8.9e-24 83.8 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EGE03317.1 - 2.2e-25 88.5 0.2 5.5e-25 87.2 0.2 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EGE03317.1 - 1.2e-10 41.1 0.1 3.7e-07 29.9 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 EGE03317.1 - 0.0013 18.5 0.0 0.0077 16.1 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain CH_2 PF06294.11 EGE03317.1 - 0.0031 17.6 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 CH-like domain in sperm protein EF-hand_8 PF13833.6 EGE03317.1 - 0.0076 16.1 0.2 0.045 13.6 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGE03317.1 - 0.017 14.6 0.0 0.23 11.1 0.0 2.6 2 0 0 2 2 2 0 EF hand SKA1 PF07160.12 EGE03317.1 - 0.093 12.6 1.5 0.19 11.5 0.9 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FliG_N PF14842.6 EGE03317.1 - 0.17 12.4 2.6 3.8 8.1 0.1 3.1 2 1 1 3 3 3 0 FliG N-terminal domain zf-RRPl_C4 PF17026.5 EGE03317.1 - 0.17 12.0 0.0 0.49 10.5 0.0 1.8 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type EF-hand_7 PF13499.6 EGE03317.1 - 0.24 11.9 2.5 0.93 10.0 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.21 EGE03317.1 - 0.26 11.8 10.4 0.71 10.4 0.0 3.1 3 1 0 3 3 3 0 Spectrin repeat G-alpha PF00503.20 EGE03320.1 - 2.3e-123 411.9 1.4 2.6e-123 411.7 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGE03320.1 - 1.7e-15 56.9 1.1 2.5e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EGE03320.1 - 6.3e-05 22.7 0.0 0.00027 20.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EGE03320.1 - 0.0012 18.3 3.0 0.053 12.9 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGE03320.1 - 0.013 15.7 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGE03320.1 - 0.019 14.7 0.1 0.051 13.3 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EGE03320.1 - 0.026 13.7 0.1 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 EGE03320.1 - 0.063 12.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EGE03320.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EGE03320.1 - 0.1 11.9 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EGE03320.1 - 0.14 12.2 0.0 9.9 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Use1 PF09753.9 EGE03321.1 - 5.1e-11 42.8 13.7 7.2e-09 35.7 13.7 2.2 1 1 0 1 1 1 1 Membrane fusion protein Use1 Hamartin PF04388.12 EGE03321.1 - 0.45 9.1 23.2 0.77 8.3 23.2 1.4 1 0 0 1 1 1 0 Hamartin protein DUF5538 PF17692.1 EGE03321.1 - 0.59 10.2 4.4 1.4 9.0 4.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5538) DUF4482 PF14818.6 EGE03321.1 - 1 10.2 6.2 0.27 12.1 1.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) HR1 PF02185.16 EGE03321.1 - 3.4 7.9 10.5 0.17 12.0 3.6 2.5 2 1 0 2 2 2 0 Hr1 repeat Macoilin PF09726.9 EGE03321.1 - 4.7 5.6 15.8 10 4.5 15.3 1.6 1 1 1 2 2 2 0 Macoilin family DUF4683 PF15735.5 EGE03321.1 - 5.3 6.5 11.7 0.32 10.6 6.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4683) Menin PF05053.13 EGE03321.1 - 8.3 4.6 9.7 12 4.1 9.7 1.2 1 0 0 1 1 1 0 Menin Acetyltransf_10 PF13673.7 EGE03322.1 - 0.029 14.3 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EGE03325.1 - 3.9e-66 223.4 0.0 9.4e-47 159.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGE03325.1 - 3e-16 60.2 0.1 8.4e-16 58.7 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Nup188_C PF18378.1 EGE03326.1 - 2.9e-138 460.7 0.0 4.7e-138 460.0 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EGE03326.1 - 2.6e-81 273.9 0.1 5.9e-68 229.7 0.0 2.6 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 EGE03327.1 - 2e-94 315.5 0.0 4.6e-94 314.3 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EGE03327.1 - 8.6e-52 175.7 0.1 8.4e-47 159.5 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EGE03327.1 - 7e-48 162.9 0.0 1.4e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGE03327.1 - 0.00095 19.0 1.2 0.0049 16.6 0.6 2.2 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 EGE03327.1 - 0.016 15.0 0.3 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGE03327.1 - 0.018 14.5 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 EGE03327.1 - 0.14 11.3 0.4 0.41 9.8 0.0 2.0 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase PTCB-BRCT PF12738.7 EGE03328.1 - 5.1e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGE03328.1 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGE03328.1 - 1.7e-05 25.1 0.0 4.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.15 EGE03328.1 - 0.00017 21.5 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 WGR domain UPF1_Zn_bind PF09416.10 EGE03329.1 - 8e-65 217.5 4.0 4.9e-64 214.9 0.5 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EGE03329.1 - 4.8e-58 196.1 0.0 7.6e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE03329.1 - 4.5e-52 177.4 5.3 4.8e-30 105.2 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EGE03329.1 - 3.1e-33 113.9 0.0 6.4e-33 112.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EGE03329.1 - 3.9e-12 46.3 0.2 3.2e-11 43.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE03329.1 - 5.6e-10 39.7 0.1 2.8e-09 37.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EGE03329.1 - 3.5e-06 27.1 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EGE03329.1 - 0.00017 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EGE03329.1 - 0.00049 19.9 0.1 1.2 8.8 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGE03329.1 - 0.002 17.4 0.6 0.035 13.4 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EGE03329.1 - 0.026 14.1 0.2 0.28 10.7 0.0 2.3 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EGE03329.1 - 0.026 13.7 0.0 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 EGE03329.1 - 0.026 14.3 0.3 0.068 12.9 0.2 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE03329.1 - 0.028 14.7 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGE03329.1 - 0.046 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF4123 PF13503.6 EGE03329.1 - 0.077 13.4 0.7 0.96 9.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) AAA_16 PF13191.6 EGE03329.1 - 0.14 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 EGE03329.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 EGE03329.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EGE03329.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC PBP1_TM PF14812.6 EGE03329.1 - 1.2 9.5 4.7 3.2 8.2 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Brix PF04427.18 EGE03330.1 - 4.7e-32 111.7 0.0 6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain PI-PLC-Y PF00387.19 EGE03332.1 - 9e-38 129.2 0.2 1.6e-37 128.3 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGE03332.1 - 2.4e-05 24.6 0.0 0.0002 21.6 0.0 2.1 1 1 0 1 1 1 1 C2 domain LPMO_10 PF03067.15 EGE03336.1 - 0.011 16.4 0.1 0.038 14.6 0.1 1.8 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading eIF-3c_N PF05470.12 EGE03337.1 - 3.5e-169 563.9 28.1 1.5e-136 456.2 4.4 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGE03337.1 - 1.8e-13 50.9 3.2 6.6e-12 45.9 0.1 3.8 2 2 2 4 4 4 1 PCI domain DASH_Ask1 PF08655.10 EGE03337.1 - 0.11 12.5 0.2 3.3 7.7 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Ask1 CDC45 PF02724.14 EGE03337.1 - 1.6 7.0 18.3 2.4 6.4 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein EAP30 PF04157.16 EGE03338.1 - 2.8e-71 239.6 0.0 3.2e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.12 EGE03339.1 - 9.2e-27 93.1 15.0 1.9e-26 92.1 15.0 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGE03339.1 - 2.3e-17 62.6 1.7 2.3e-17 62.6 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.21 EGE03340.1 - 1.2e-116 390.2 1.8 1.3e-116 390.1 0.4 1.8 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EGE03340.1 - 2.2e-68 229.7 1.2 3.7e-68 228.9 0.4 1.9 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EGE03340.1 - 1.1e-46 159.5 0.0 2.2e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EGE03340.1 - 4.9e-25 87.4 9.9 4.9e-25 87.4 9.9 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EGE03340.1 - 0.00082 18.4 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral HSP70 PF00012.20 EGE03341.1 - 3.7e-239 794.9 19.7 3.8e-190 633.1 5.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGE03341.1 - 1.3e-14 53.8 6.2 9.6e-13 47.6 2.1 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGE03341.1 - 8.9e-05 22.3 0.0 0.0003 20.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EGE03341.1 - 0.005 16.1 5.9 0.086 12.1 0.2 3.4 3 1 1 4 4 4 1 StbA protein Scaffolding_pro PF11418.8 EGE03341.1 - 0.058 14.0 0.7 0.15 12.6 0.7 1.6 1 0 0 1 1 1 0 Phi29 scaffolding protein SMBP PF16785.5 EGE03341.1 - 0.07 13.3 3.7 0.089 13.0 1.2 2.3 2 0 0 2 2 2 0 Small metal-binding protein FtsA PF14450.6 EGE03341.1 - 3.9 8.0 12.8 1.2 9.6 0.9 3.9 3 3 0 3 3 3 0 Cell division protein FtsA Histone_HNS PF00816.21 EGE03341.1 - 6.9 7.6 11.4 29 5.6 4.7 3.3 3 0 0 3 3 3 0 H-NS histone family DUF2415 PF10313.9 EGE03342.1 - 9.7e-16 57.4 0.0 2.5e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Phage_Mu_F PF04233.14 EGE03342.1 - 0.12 13.2 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein PRIMA1 PF16101.5 EGE03342.1 - 4 7.5 6.6 9.8 6.2 6.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGE03342.1 - 4.8 6.6 9.3 9.3 5.6 9.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DSHCT PF08148.12 EGE03344.1 - 2e-51 173.9 0.5 4.3e-51 172.8 0.5 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EGE03344.1 - 1.6e-39 134.8 0.0 3e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EGE03344.1 - 9.9e-18 65.0 0.1 3.6e-17 63.2 0.1 1.9 1 1 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EGE03344.1 - 4.9e-17 62.3 0.0 1.1e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03344.1 - 6.3e-06 26.5 0.0 1.8e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03344.1 - 0.00021 21.4 0.0 0.00047 20.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBN_N PF03810.19 EGE03345.1 - 1e-15 57.4 0.0 1.4e-13 50.5 0.0 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGE03345.1 - 1.3e-06 27.5 0.0 3.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.6 EGE03345.1 - 4.5e-05 23.7 0.1 0.45 10.9 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats GRIP PF01465.20 EGE03345.1 - 0.00083 19.2 0.0 0.0092 15.9 0.0 2.9 1 1 0 1 1 1 1 GRIP domain Xpo1 PF08389.12 EGE03345.1 - 0.0018 18.3 2.3 0.023 14.7 0.1 3.6 3 1 0 3 3 3 1 Exportin 1-like protein RTP1_C1 PF10363.9 EGE03345.1 - 0.0052 16.9 0.1 0.13 12.5 0.1 2.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 EGE03345.1 - 0.0062 15.1 0.2 0.13 10.8 0.0 2.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Vac14_Fab1_bd PF12755.7 EGE03345.1 - 0.056 14.1 0.2 1.6 9.4 0.0 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Telomere_reg-2 PF10193.9 EGE03345.1 - 0.091 13.2 0.4 0.46 11.0 0.1 2.4 2 0 0 2 2 2 0 Telomere length regulation protein HEAT_EZ PF13513.6 EGE03345.1 - 0.14 12.7 1.9 22 5.7 0.0 4.6 6 0 0 6 6 6 0 HEAT-like repeat RRM_1 PF00076.22 EGE03346.1 - 5.3e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE03346.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGE03346.1 - 0.00075 19.3 0.0 0.0044 16.8 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EGE03346.1 - 0.023 14.9 0.4 0.26 11.5 0.1 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Mito_fiss_reg PF05308.11 EGE03347.1 - 0.03 14.4 6.4 0.053 13.6 6.1 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator CENP-F_N PF10481.9 EGE03347.1 - 0.1 12.2 7.2 0.54 9.8 7.2 1.9 1 1 0 1 1 1 0 Cenp-F N-terminal domain SlyX PF04102.12 EGE03347.1 - 0.39 11.4 3.9 10 6.9 0.1 2.3 2 0 0 2 2 2 0 SlyX SPX PF03105.19 EGE03347.1 - 0.96 9.3 10.2 1.3 8.9 10.2 1.1 1 0 0 1 1 1 0 SPX domain FlaC_arch PF05377.11 EGE03347.1 - 2.2 8.7 4.4 1.9 8.9 0.3 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 EGE03347.1 - 2.7 7.8 4.9 1.4 8.8 0.8 2.0 2 0 0 2 2 2 0 Septum formation initiator DegS PF05384.11 EGE03347.1 - 5.2 6.5 9.6 1.3 8.5 5.6 1.8 2 0 0 2 2 2 0 Sensor protein DegS AP3D1 PF06375.11 EGE03348.1 - 0.0065 16.7 8.6 0.0065 16.7 8.6 3.1 3 0 0 3 3 3 1 AP-3 complex subunit delta-1 DUF501 PF04417.12 EGE03348.1 - 3.2 7.6 5.4 11 5.8 5.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Ferlin_C PF16165.5 EGE03348.1 - 6.4 6.7 8.7 13 5.7 2.8 2.5 2 0 0 2 2 2 0 Ferlin C-terminus DbpA PF03880.15 EGE03349.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain MFS_1 PF07690.16 EGE03351.1 - 2.7e-33 115.3 25.7 2.7e-32 112.1 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE03351.1 - 2.1e-08 33.5 7.1 2.1e-08 33.5 7.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_TACC PF12709.7 EGE03352.1 - 1.5e-09 38.2 24.5 1.4e-08 35.1 3.5 4.4 3 1 2 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 EGE03352.1 - 0.013 15.6 5.3 0.013 15.6 5.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 EGE03352.1 - 0.11 12.4 0.7 1.6 8.7 0.0 3.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF4407 PF14362.6 EGE03352.1 - 0.23 10.7 29.1 0.31 10.3 8.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Z1 PF10593.9 EGE03352.1 - 0.53 9.7 7.0 5.9 6.3 1.4 2.6 2 0 0 2 2 2 0 Z1 domain MscS_porin PF12795.7 EGE03352.1 - 0.62 9.6 28.7 5.3 6.5 8.1 3.7 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.6 EGE03352.1 - 0.69 8.5 23.2 0.47 9.0 8.0 2.2 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.10 EGE03352.1 - 0.89 9.7 13.2 2.2 8.5 0.6 3.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 EGE03352.1 - 1 9.0 31.2 0.035 13.8 14.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF2959 PF11172.8 EGE03352.1 - 1.3 9.2 17.3 0.95 9.6 11.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2959) Fez1 PF06818.15 EGE03352.1 - 2.3 8.6 37.8 25 5.2 20.0 2.7 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 EGE03352.1 - 3.6 7.8 45.5 0.42 10.8 6.7 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EGE03352.1 - 6.3 6.5 46.5 3.2 7.5 31.3 2.7 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.6 EGE03352.1 - 6.4 6.1 33.9 1 8.7 12.9 2.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding FAD_binding_3 PF01494.19 EGE03353.1 - 7.1e-12 45.2 0.2 2e-11 43.8 0.0 1.8 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EGE03353.1 - 0.00011 21.4 1.0 0.53 9.3 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 EGE03353.1 - 0.00034 20.3 0.1 0.0008 19.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE03353.1 - 0.0056 16.9 1.1 0.053 13.8 0.1 2.8 2 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGE03353.1 - 0.035 14.1 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.10 EGE03353.1 - 0.05 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DegT_DnrJ_EryC1 PF01041.17 EGE03353.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 EGE03355.1 - 2e-30 105.7 0.4 3.9e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE03355.1 - 0.0047 17.0 18.0 0.0082 16.2 18.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sof1 PF04158.14 EGE03355.1 - 0.035 14.4 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 Sof1-like domain MFS_1 PF07690.16 EGE03356.1 - 4.1e-16 58.9 23.5 4.1e-16 58.9 23.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGE03356.1 - 1.7e-11 44.1 5.1 5.3e-11 42.5 5.1 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Ni_hydr_CYTB PF01292.20 EGE03356.1 - 4.9 6.7 10.5 19 4.8 10.5 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Amidohydro_1 PF01979.20 EGE03357.1 - 1.1e-14 54.6 0.0 6.9e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGE03357.1 - 5.8e-09 35.9 0.1 9.7e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family GMC_oxred_C PF05199.13 EGE03358.1 - 3.7e-37 128.1 0.0 5.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EGE03358.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Aldedh PF00171.22 EGE03359.1 - 2.8e-160 533.8 0.4 3.3e-160 533.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EGE03359.1 - 0.0087 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family Glucosamine_iso PF01182.20 EGE03360.1 - 3.2e-23 82.8 0.0 4.9e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 EGE03361.1 - 3.6e-58 197.5 0.0 5.4e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGE03361.1 - 8.9e-07 29.1 0.3 2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EGE03361.1 - 3.3e-05 24.1 0.0 9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE03361.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE03361.1 - 0.025 14.5 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 EGE03361.1 - 0.045 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain K_channel_TID PF07941.11 EGE03361.1 - 9.1 6.8 18.5 4.1 7.9 4.5 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain NDT80_PhoG PF05224.12 EGE03362.1 - 6.3e-34 117.8 0.2 6.3e-33 114.6 0.0 2.4 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family KRTAP PF11759.8 EGE03362.1 - 0.038 14.5 8.8 0.077 13.5 8.8 1.4 1 0 0 1 1 1 0 Keratin-associated matrix TFIIA PF03153.13 EGE03362.1 - 0.66 9.9 21.7 2.5 8.0 13.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sporozoite_P67 PF05642.11 EGE03362.1 - 2.5 6.1 13.3 4.6 5.2 13.2 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Hexokinase_2 PF03727.16 EGE03363.1 - 7.1e-54 182.8 0.0 1.3e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGE03363.1 - 2.5e-46 158.1 0.0 3.9e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase AATF-Che1 PF13339.6 EGE03363.1 - 0.21 12.3 1.8 0.46 11.1 1.8 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor p450 PF00067.22 EGE03365.1 - 2.9e-37 128.5 0.0 4.4e-34 118.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Emaravirus_P4 PF16505.5 EGE03365.1 - 0.19 10.8 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily Hep_59 PF07052.11 EGE03366.1 - 4.6e-19 69.1 0.1 4.6e-19 69.1 0.1 2.4 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 DUF3435 PF11917.8 EGE03367.1 - 2.8e-54 184.7 3.0 7.3e-34 117.4 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Totivirus_coat PF05518.11 EGE03367.1 - 0.44 8.5 2.1 0.7 7.9 2.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein JHD PF17811.1 EGE03368.1 - 0.027 15.0 8.9 0.061 13.9 1.7 2.3 1 1 1 2 2 2 0 Jumonji helical domain TMEM215 PF15746.5 EGE03368.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 TMEM215 family DUF3074 PF11274.8 EGE03368.1 - 2.7 7.9 4.8 7.5 6.5 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) TRP PF06011.12 EGE03369.1 - 1.2e-138 462.4 9.2 1.6e-138 462.0 9.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGE03369.1 - 4.3e-31 108.1 0.2 6.7e-31 107.5 0.2 1.3 1 0 0 1 1 1 1 ML-like domain RseC_MucC PF04246.12 EGE03369.1 - 5.7 6.9 10.0 5.4 7.0 0.8 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TFIIIC_sub6 PF10419.9 EGE03370.1 - 4.2e-26 90.6 0.0 6.7e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain GATA PF00320.27 EGE03370.1 - 0.14 11.8 0.3 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 GATA zinc finger Bac_GDH PF05088.12 EGE03372.1 - 1.7e-14 52.4 0.0 2e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EGE03372.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.16 EGE03374.1 - 8.8e-13 47.9 22.2 4.6e-08 32.4 24.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE03374.1 - 6.6e-05 21.9 5.2 6.6e-05 21.9 5.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE03375.1 - 0.051 12.5 0.2 0.06 12.3 0.2 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 EGE03377.1 - 1e-31 108.9 8.7 1.3e-11 44.5 0.7 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE03377.1 - 6.3e-31 106.4 3.4 8.3e-15 54.8 1.8 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGE03377.1 - 7.2e-05 22.9 1.2 0.065 13.4 0.2 2.9 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EGE03377.1 - 0.00092 19.1 0.2 0.92 9.4 0.0 2.6 2 1 1 3 3 3 2 Myb DNA-binding like Rap1_C PF11626.8 EGE03377.1 - 0.021 14.9 1.6 3.5 7.8 1.2 2.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGE03377.1 - 0.16 12.0 0.1 18 5.4 0.0 2.9 1 1 2 3 3 3 0 SLIDE RAP80_UIM PF18282.1 EGE03377.1 - 0.22 11.3 0.6 0.43 10.4 0.1 1.7 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif PPR_2 PF13041.6 EGE03378.1 - 7.6e-11 42.0 0.3 0.021 15.0 0.0 6.7 5 3 2 7 7 7 2 PPR repeat family PPR PF01535.20 EGE03378.1 - 2e-07 30.8 5.2 0.65 10.4 0.0 7.5 8 0 0 8 8 8 1 PPR repeat TPR_14 PF13428.6 EGE03378.1 - 0.009 16.8 0.0 23 6.1 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat DDT PF02791.17 EGE03378.1 - 0.01 16.1 0.5 0.18 12.1 0.1 2.9 2 0 0 2 2 2 0 DDT domain T2SS_PulS_OutS PF09691.10 EGE03378.1 - 0.11 12.7 0.3 6.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) PPR_3 PF13812.6 EGE03378.1 - 0.17 12.0 0.9 16 5.7 0.0 4.2 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Ribosomal_S18 PF01084.20 EGE03379.1 - 1.1e-16 60.8 0.1 1.4e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.10 EGE03379.1 - 0.0039 17.2 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Cro Ribosomal_L13 PF00572.18 EGE03379.1 - 0.098 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13 WD40 PF00400.32 EGE03380.1 - 7.9e-33 112.0 27.9 5e-05 24.0 0.3 10.3 10 1 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03380.1 - 9.2e-18 64.3 4.2 3.9e-05 23.9 0.0 6.4 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGE03380.1 - 0.00073 19.4 1.0 22 5.1 0.0 5.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat BBS2_N PF14781.6 EGE03380.1 - 0.0012 18.7 0.0 0.031 14.2 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 EGE03380.1 - 0.0015 17.5 0.2 27 3.6 0.0 4.5 4 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IRF PF00605.17 EGE03380.1 - 0.16 12.3 1.0 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Rrp44_S1 PF17215.3 EGE03383.1 - 2.9e-27 94.5 3.4 5.6e-27 93.5 3.4 1.5 1 1 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 EGE03383.1 - 0.051 13.9 1.0 0.12 12.7 1.0 1.9 1 1 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Peptidase_M36 PF02128.15 EGE03384.1 - 1.5e-94 317.3 8.6 2.9e-52 178.1 4.8 2.2 2 0 0 2 2 2 2 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGE03384.1 - 6.8e-14 51.4 7.4 3e-13 49.4 7.4 2.1 1 1 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif MFS_1 PF07690.16 EGE03386.1 - 3.3e-26 92.1 38.8 3.3e-26 92.1 38.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 EGE03386.1 - 0.055 14.1 0.5 0.13 12.9 0.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3328 PF11807.8 EGE03387.1 - 1.4e-22 80.6 0.1 2e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ycf9 PF01737.17 EGE03387.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 YCF9 DUF3328 PF11807.8 EGE03389.1 - 4.9e-22 78.8 0.1 6.3e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EGE03390.1 - 2.9e-40 138.4 2.1 3.5e-40 138.1 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.18 EGE03391.1 - 1.7e-20 73.3 0.1 2.5e-20 72.7 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGE03391.1 - 0.057 13.3 0.0 0.47 10.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Carb_anhydrase PF00194.21 EGE03393.1 - 2.3e-33 115.8 0.0 3.8e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 EGE03393.1 - 0.018 15.0 0.3 0.1 12.5 0.1 2.1 1 1 1 2 2 2 0 Putative carbonic anhydrase Cu-oxidase_3 PF07732.15 EGE03393.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase Alk_phosphatase PF00245.20 EGE03395.1 - 5.9e-107 358.2 0.0 7.1e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGE03395.1 - 8.5e-07 28.6 0.0 4.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily FUSC_2 PF13515.6 EGE03396.1 - 2.4e-31 108.5 11.0 2.4e-31 108.5 11.0 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGE03396.1 - 1.2e-05 24.1 18.0 8e-05 21.4 15.1 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 EGE03396.1 - 0.00028 20.8 0.4 0.00059 19.7 0.4 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EGE03396.1 - 0.017 14.0 24.6 0.057 12.2 11.5 3.5 3 2 0 3 3 3 0 Aluminium activated malate transporter TraS PF10624.9 EGE03396.1 - 0.089 12.7 1.9 5.9 6.8 0.7 2.6 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS YajC PF02699.15 EGE03396.1 - 0.11 12.4 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit SAGA-Tad1 PF12767.7 EGE03397.1 - 2e-23 83.4 0.0 2.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 EGE03398.1 - 9.6e-54 181.8 7.9 2.1e-53 180.7 7.9 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGE03398.1 - 1.6e-29 100.0 26.8 0.0034 18.1 0.1 14.6 5 4 10 15 15 14 8 Tetratricopeptide repeat TPR_19 PF14559.6 EGE03398.1 - 2e-26 92.2 7.4 1e-06 29.1 0.1 9.8 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE03398.1 - 1.7e-10 40.2 10.0 0.25 11.6 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGE03398.1 - 5.1e-09 35.9 1.5 2.3 8.8 0.0 9.0 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE03398.1 - 1.7e-08 34.0 4.4 0.083 13.1 0.0 8.0 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE03398.1 - 1.8e-07 31.7 13.6 0.19 12.4 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.8 EGE03398.1 - 3e-07 29.7 8.3 0.0088 15.0 0.0 5.6 3 1 3 6 6 6 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EGE03398.1 - 6e-06 26.3 3.6 0.038 14.1 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE03398.1 - 9.1e-05 22.1 1.4 29 4.4 0.0 6.8 7 1 1 8 8 8 0 TPR repeat TPR_1 PF00515.28 EGE03398.1 - 0.00015 21.4 1.6 0.79 9.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 EGE03398.1 - 0.0069 16.4 0.2 31 4.6 0.0 4.7 6 0 0 6 6 6 0 ZNRF-3 Ectodomain TPR_12 PF13424.6 EGE03398.1 - 0.024 14.9 6.5 18 5.7 0.2 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGE03398.1 - 0.048 12.4 0.0 3.1 6.4 0.0 3.6 4 1 0 5 5 5 0 Protein of unknown function (DUF3808) AdenylateSensor PF16579.5 EGE03398.1 - 0.08 13.4 0.6 22 5.6 0.0 3.8 3 1 1 4 4 4 0 Adenylate sensor of SNF1-like protein kinase TPR_21 PF09976.9 EGE03398.1 - 0.09 12.5 19.9 0.98 9.1 0.1 4.8 4 1 1 6 6 6 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EGE03398.1 - 0.17 12.0 2.4 1e+02 3.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGE03398.1 - 1.4 8.9 3.0 70 3.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE03398.1 - 4.1 8.3 12.8 48 4.9 0.0 7.0 9 0 0 9 9 6 0 Tetratricopeptide repeat RrnaAD PF00398.20 EGE03399.1 - 3.1e-64 216.6 0.0 4.5e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGE03399.1 - 1.9e-07 31.7 0.0 4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03399.1 - 1.3e-05 25.7 0.0 3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGE03399.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EGE03399.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGE03399.1 - 0.0009 19.9 0.0 0.0071 17.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE03399.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE03399.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EGE03399.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EGE03399.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGE03399.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGE03399.1 - 0.03 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EGE03399.1 - 0.038 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EGE03399.1 - 0.04 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.12 EGE03399.1 - 0.053 12.6 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.17 EGE03399.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 EGE03399.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 EGE03400.1 - 3.8e-31 108.4 0.7 4.9e-29 101.5 0.3 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MCPVI PF02993.14 EGE03400.1 - 2.7 7.8 8.9 0.15 11.8 3.4 1.7 2 0 0 2 2 2 0 Minor capsid protein VI Herpes_pp85 PF04637.12 EGE03401.1 - 0.74 8.2 2.2 0.74 8.2 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RRM_1 PF00076.22 EGE03402.1 - 8.1e-33 112.1 0.3 2.7e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE03402.1 - 1.1e-11 44.7 0.2 0.00019 21.5 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 EGE03402.1 - 0.0042 17.1 0.8 2 8.5 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.6 EGE03402.1 - 0.011 15.7 0.1 5.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Phytochelatin PF05023.14 EGE03402.1 - 0.078 12.2 0.8 1.3 8.1 0.0 2.7 3 0 0 3 3 3 0 Phytochelatin synthase MCRS_N PF13325.6 EGE03402.1 - 0.49 10.4 2.0 1 9.3 2.0 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein LOH1CR12 PF10158.9 EGE03402.1 - 0.78 9.8 4.2 2.2 8.3 4.2 1.7 1 0 0 1 1 1 0 Tumour suppressor protein JmjC PF02373.22 EGE03404.1 - 4.8e-09 36.6 0.0 6.5e-08 33.0 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EGE03404.1 - 4.5e-08 32.8 8.0 4.5e-08 32.8 8.0 2.0 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.6 EGE03404.1 - 6.2e-08 32.7 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JHD PF17811.1 EGE03404.1 - 1.2e-06 29.0 0.3 2.3e-06 28.1 0.3 1.4 1 0 0 1 1 1 1 Jumonji helical domain PHD_2 PF13831.6 EGE03404.1 - 2.5 7.7 9.8 1.8 8.2 7.5 2.0 2 0 0 2 2 2 0 PHD-finger COG4 PF08318.12 EGE03405.1 - 5e-124 413.7 0.0 6.5e-124 413.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein SIR2 PF02146.17 EGE03406.1 - 1.6e-56 191.0 0.0 2.4e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGE03406.1 - 0.095 12.4 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Hexokinase_2 PF03727.16 EGE03407.1 - 1e-81 273.9 0.0 1.4e-81 273.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGE03407.1 - 2.7e-72 242.8 0.0 3.6e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase ANAPC4_WD40 PF12894.7 EGE03408.1 - 0.00016 21.9 0.1 0.61 10.4 0.2 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE03408.1 - 0.0013 19.5 4.9 1.3 10.1 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat SGL PF08450.12 EGE03408.1 - 0.015 14.9 0.2 0.17 11.4 0.0 2.1 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region PikAIV_N PF18605.1 EGE03408.1 - 0.23 11.0 5.8 2.3 7.9 0.7 2.9 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain STIMATE PF12400.8 EGE03409.1 - 1e-37 129.5 7.0 1.8e-37 128.6 7.0 1.4 1 0 0 1 1 1 1 STIMATE family Mucin PF01456.17 EGE03409.1 - 3.5 7.6 19.8 6.3 6.8 19.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RRM_1 PF00076.22 EGE03410.1 - 3.7e-19 68.3 0.3 5.6e-19 67.7 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE03410.1 - 5e-06 26.1 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE03410.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Ammonium_transp PF00909.21 EGE03411.1 - 3.6e-72 243.3 14.5 1.8e-49 168.5 8.2 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family E1-E2_ATPase PF00122.20 EGE03412.1 - 3e-46 157.2 0.3 3e-46 157.2 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE03412.1 - 1e-40 139.4 0.2 1e-40 139.4 0.2 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGE03412.1 - 8.7e-22 76.6 0.0 2.4e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGE03412.1 - 3e-20 73.4 3.4 6.9e-20 72.2 2.5 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE03412.1 - 1.7e-11 44.1 0.0 3.6e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGE03412.1 - 1.8e-05 24.6 1.7 0.00036 20.4 0.9 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CARD_2 PF16739.5 EGE03412.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Caspase recruitment domain Rad21_Rec8_N PF04825.13 EGE03413.1 - 1.3e-37 128.3 0.0 2.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGE03413.1 - 3.2e-07 29.5 0.3 6.9e-07 28.5 0.3 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Zn_clus PF00172.18 EGE03417.1 - 0.0035 17.4 9.0 0.0035 17.4 9.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGE03417.1 - 0.039 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.17 EGE03419.1 - 3.1e-31 107.9 0.0 4.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase RSN1_7TM PF02714.15 EGE03420.1 - 5e-85 285.1 28.9 5e-85 285.1 28.9 1.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGE03420.1 - 5.8e-47 159.4 1.0 5.8e-47 159.4 1.0 3.2 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGE03420.1 - 5.9e-28 98.3 0.9 8e-16 58.8 0.1 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EGE03420.1 - 6.9e-14 51.8 1.0 1.5e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter SnoaL_2 PF12680.7 EGE03421.1 - 2e-06 28.4 0.0 3.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGE03421.1 - 0.00026 20.8 0.0 0.00047 20.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.18 EGE03421.1 - 0.072 12.6 0.0 1.7 8.2 0.0 2.3 2 1 1 3 3 3 0 Dienelactone hydrolase family Indigoidine_A PF04227.12 EGE03422.1 - 2.5e-123 411.1 0.6 3.5e-123 410.6 0.6 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EGE03422.1 - 2.9e-13 49.8 0.0 1.6e-07 30.9 0.0 3.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Ribophorin_I PF04597.14 EGE03423.1 - 3.8e-111 372.4 6.2 1.2e-105 354.3 1.7 2.0 1 1 1 2 2 2 2 Ribophorin I GlgS PF08971.11 EGE03423.1 - 0.18 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein VTC PF09359.10 EGE03424.1 - 7.1e-100 333.9 0.4 1e-99 333.4 0.4 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EGE03424.1 - 7.7e-15 55.7 4.8 7.5e-06 26.1 0.0 3.4 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 EGE03424.1 - 2.5e-11 43.8 3.6 2.5e-11 43.8 3.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.23 EGE03425.1 - 1.7e-102 341.3 0.0 2.5e-102 340.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGE03425.1 - 8.2e-37 125.9 0.3 1.6e-36 125.0 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGE03425.1 - 1.4e-28 99.1 2.3 3.1e-28 98.0 2.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGE03425.1 - 1e-18 67.8 0.0 3.2e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE03425.1 - 7.2e-06 25.5 0.0 0.00027 20.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE03425.1 - 1.6e-05 25.0 0.1 0.00011 22.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGE03425.1 - 0.0024 17.7 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 EGE03426.1 - 0.0093 16.4 0.0 0.034 14.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGE03426.1 - 0.018 15.6 0.2 0.31 11.6 0.1 2.3 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE03426.1 - 0.021 15.4 0.0 1.4 9.6 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) HeLo PF14479.6 EGE03427.1 - 1.3e-09 38.2 0.2 3.4e-09 36.8 0.1 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation Band_7 PF01145.25 EGE03428.1 - 1.7e-22 80.3 6.2 2.9e-22 79.5 6.2 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.6 EGE03429.1 - 2.4e-32 111.2 2.5 2.4e-32 111.2 2.5 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EGE03429.1 - 7e-20 70.6 0.0 1.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EGE03429.1 - 4.7e-18 64.5 8.8 2.2e-17 62.4 8.8 2.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EGE03429.1 - 0.01 15.9 0.1 1 9.5 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif Spo7_2_N PF15407.6 EGE03429.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 EGE03429.1 - 0.022 14.6 0.0 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EGE03429.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif MCCD1 PF15707.5 EGE03429.1 - 0.54 10.7 4.1 0.55 10.7 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 SNF2_N PF00176.23 EGE03430.1 - 3.6e-22 78.6 0.1 7.2e-21 74.3 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.17 EGE03430.1 - 6.9e-19 68.4 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 EGE03430.1 - 0.0052 17.1 0.0 0.049 14.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGE03430.1 - 0.51 10.4 15.5 0.48 10.5 5.9 2.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGE03430.1 - 0.93 9.5 23.9 0.45 10.5 11.7 2.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGE03430.1 - 9.4 6.2 19.2 3.4 7.6 6.7 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 2Fe-2S_thioredx PF01257.19 EGE03431.1 - 5.6e-59 198.1 0.1 7.1e-59 197.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF4139 PF13598.6 EGE03432.1 - 3e-19 69.6 0.0 3.1e-18 66.3 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EGE03432.1 - 1.7e-15 57.2 9.2 1.7e-15 57.2 9.2 3.2 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.6 EGE03432.1 - 0.033 12.8 6.1 0.048 12.3 6.1 1.1 1 0 0 1 1 1 0 AAA domain Nucleoporin_FG PF13634.6 EGE03432.1 - 0.43 11.5 6.0 1.2 10.0 6.0 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region RR_TM4-6 PF06459.12 EGE03432.1 - 0.46 10.3 7.4 0.93 9.3 7.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 EGE03432.1 - 0.9 7.4 7.2 1.3 6.8 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 EGE03432.1 - 4.6 7.3 11.6 7.9 6.5 11.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sua5_yciO_yrdC PF01300.18 EGE03433.1 - 8.7e-54 181.7 0.0 1.4e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EGE03433.1 - 5.4e-32 111.2 0.0 9.4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FbpA PF05833.11 EGE03434.1 - 9.2e-34 117.0 9.2 1.7e-33 116.1 9.2 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EGE03434.1 - 8.2e-28 97.2 0.0 1.7e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Clat_adaptor_s PF01217.20 EGE03435.1 - 6e-14 52.2 0.0 1.3e-12 47.8 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain PAG PF15347.6 EGE03436.1 - 0.012 14.7 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TLE_N PF03920.15 EGE03436.1 - 0.06 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF948 PF06103.11 EGE03437.1 - 0.031 14.5 1.2 0.07 13.4 1.2 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TTKRSYEDQ PF10212.9 EGE03437.1 - 0.041 12.9 5.5 0.066 12.2 5.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF1515 PF07439.11 EGE03437.1 - 0.13 12.3 10.5 0.034 14.2 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) End3 PF12761.7 EGE03437.1 - 0.15 12.2 17.6 0.32 11.2 12.7 2.6 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF4407 PF14362.6 EGE03437.1 - 0.78 9.0 12.4 1.7 7.9 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 EGE03437.1 - 1.1 9.1 18.8 1.1 9.0 13.6 3.1 2 1 1 3 3 3 0 Phage minor structural protein GP20 Bacillus_HBL PF05791.11 EGE03437.1 - 1.5 8.6 7.7 0.61 9.9 3.7 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 EGE03437.1 - 2.2 8.3 10.9 7 6.7 10.9 1.8 1 0 0 1 1 1 0 Laminin Domain II FlaC_arch PF05377.11 EGE03437.1 - 2.8 8.4 11.8 12 6.4 0.3 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EGE03437.1 - 2.8 8.0 6.8 1.5 8.9 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 EGE03437.1 - 6.6 5.9 12.0 12 5.0 12.0 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 FapA PF03961.13 EGE03437.1 - 9.2 4.7 9.7 19 3.7 9.7 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pyridoxal_deC PF00282.19 EGE03438.1 - 5e-18 65.0 0.0 1.6e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_L16 PF00252.18 EGE03439.1 - 4e-43 146.6 0.1 5.6e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Lambda_CIII PF02061.16 EGE03440.1 - 0.17 12.0 0.2 13 5.9 0.1 2.6 2 0 0 2 2 2 0 Lambda Phage CIII RTC4 PF14474.6 EGE03442.1 - 8.6e-21 74.3 0.0 1.9e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain DUF3435 PF11917.8 EGE03442.1 - 2e-12 46.8 0.1 2.9e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_jaz PF12171.8 EGE03442.1 - 0.045 14.0 1.1 0.045 14.0 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding UPF0547 PF10571.9 EGE03442.1 - 0.2 11.8 2.0 1.5 8.9 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-Di19 PF05605.12 EGE03442.1 - 9.9 6.6 7.0 8.9 6.7 0.0 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HSP70 PF00012.20 EGE03453.1 - 3 5.9 9.9 3.7 5.6 9.9 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4911 PF16256.5 EGE03455.1 - 0.57 10.2 2.4 31 4.7 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4911) HTH_29 PF13551.6 EGE03456.1 - 0.096 12.7 0.3 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix RNase_H PF00075.24 EGE03458.1 - 0.00095 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 RNase H BTD PF09270.10 EGE03460.1 - 0.061 13.5 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain FAD_binding_2 PF00890.24 EGE03461.1 - 1.5e-83 281.2 0.1 2e-83 280.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGE03461.1 - 2e-09 37.3 3.5 1.9e-08 34.1 1.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EGE03461.1 - 7.2e-08 32.4 2.8 2.4e-07 30.7 2.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGE03461.1 - 4.2e-07 29.5 0.3 0.0027 17.0 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGE03461.1 - 1e-05 25.7 3.6 2.8e-05 24.2 3.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE03461.1 - 1.1e-05 24.9 0.3 4.9e-05 22.7 0.1 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE03461.1 - 1.9e-05 23.6 0.3 1.9e-05 23.6 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EGE03461.1 - 2.8e-05 23.5 0.6 6.1e-05 22.4 0.6 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EGE03461.1 - 0.0016 17.8 0.4 0.0026 17.1 0.2 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UPF0227 PF05728.12 EGE03461.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.22 EGE03461.1 - 0.15 11.1 0.7 0.28 10.2 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA PF00004.29 EGE03463.1 - 2.4e-19 70.1 0.0 6.7e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE03463.1 - 0.00012 22.6 0.4 0.0013 19.2 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGE03463.1 - 0.00053 20.0 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGE03463.1 - 0.0039 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGE03463.1 - 0.0054 17.0 0.9 0.048 13.9 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EGE03463.1 - 0.0073 16.9 0.0 0.045 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGE03463.1 - 0.014 15.1 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 EGE03463.1 - 0.017 14.7 0.1 0.12 12.1 0.0 2.1 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.21 EGE03463.1 - 0.041 13.3 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGE03463.1 - 0.073 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EGE03463.1 - 0.08 13.2 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGE03463.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EGE03463.1 - 0.2 11.0 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 KaiC FA_hydroxylase PF04116.13 EGE03464.1 - 2.5e-22 79.6 12.1 2.5e-22 79.6 12.1 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HA2 PF04408.23 EGE03465.1 - 5.8e-21 74.8 0.0 5.8e-21 74.8 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGE03465.1 - 2.6e-12 47.1 0.0 6.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGE03465.1 - 7.8e-12 45.4 0.0 2.4e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGE03465.1 - 0.00056 19.7 0.0 0.0016 18.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.6 EGE03465.1 - 0.0048 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGE03465.1 - 0.035 14.4 0.0 0.12 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EGE03465.1 - 0.1 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EGE03465.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zn_clus PF00172.18 EGE03466.1 - 4.3e-08 33.1 11.8 7.7e-08 32.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 EGE03467.1 - 1.6e-39 135.7 4.0 2.1e-39 135.3 4.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Fungal_lectin PF07938.12 EGE03468.1 - 5.9e-144 479.0 0.2 6.7e-144 478.8 0.2 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin TauD PF02668.16 EGE03469.1 - 7.8e-30 104.6 0.0 1.2e-29 104.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TSSC4 PF15264.6 EGE03469.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Complex1_LYR_2 PF13233.6 EGE03471.1 - 5.5e-20 71.9 0.0 7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGE03471.1 - 3.7e-09 36.5 0.0 6.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 EGE03472.1 - 0.0046 16.5 0.1 1.6 8.2 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 EGE03472.1 - 0.12 13.2 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03472.1 - 0.16 12.7 0.0 0.29 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 EGE03473.1 - 9.2e-06 25.5 1.6 3.2e-05 23.7 0.1 2.6 1 1 1 2 2 2 1 F-box-like F-box_4 PF15966.5 EGE03473.1 - 0.0021 17.9 0.1 0.0045 16.9 0.1 1.5 1 0 0 1 1 1 1 F-box F-box PF00646.33 EGE03473.1 - 0.0081 16.0 0.1 0.024 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain zf-C2H2 PF00096.26 EGE03475.1 - 1.8e-05 24.9 2.4 0.063 13.8 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.6 EGE03475.1 - 0.076 13.5 0.4 0.16 12.5 0.4 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_4 PF13894.6 EGE03475.1 - 0.15 13.0 10.1 0.84 10.6 0.0 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger FEZ PF07763.13 EGE03478.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein DUF936 PF06075.12 EGE03479.1 - 0.0036 16.3 10.5 0.0041 16.1 10.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) DUF4407 PF14362.6 EGE03479.1 - 0.16 11.3 11.0 0.19 11.0 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4778 PF16008.5 EGE03479.1 - 0.97 9.4 8.9 1.1 9.2 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Tmemb_9 PF05434.11 EGE03479.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.5 3 0 0 3 3 3 0 TMEM9 Paramyxo_ncap PF00973.19 EGE03479.1 - 3.8 6.3 9.6 5 5.9 9.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PBP_sp32 PF07222.12 EGE03479.1 - 7.5 5.9 14.3 11 5.4 14.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SLC12 PF03522.15 EGE03479.1 - 9.3 5.2 10.2 12 4.8 10.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 EGE03479.1 - 9.3 5.4 7.6 24 4.0 8.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter GTP_EFTU PF00009.27 EGE03480.1 - 3.6e-09 36.4 0.0 8.2e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE03480.1 - 0.0016 18.4 0.3 0.4 10.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EGE03480.1 - 0.008 16.7 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGE03480.1 - 0.0094 16.5 0.0 0.03 14.8 0.1 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EGE03480.1 - 0.016 15.6 0.2 0.063 13.7 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGE03480.1 - 0.026 14.3 0.2 0.066 13.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGE03480.1 - 0.044 13.1 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EGE03480.1 - 0.066 13.3 0.1 0.37 10.9 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGE03480.1 - 0.15 11.8 0.1 7.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pkr1 PF08636.10 EGE03481.1 - 2e-30 104.7 4.5 2.7e-30 104.3 4.5 1.2 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.9 EGE03481.1 - 0.17 12.2 4.0 1.9 8.9 3.9 2.1 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) ANAPC2 PF08672.11 EGE03482.1 - 2e-22 79.4 0.3 5.6e-22 78.0 0.3 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EGE03482.1 - 3.1e-22 78.9 0.2 5.6e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Cullin family DUF3235 PF11574.8 EGE03482.1 - 0.14 13.0 6.1 0.32 11.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) SNF2_N PF00176.23 EGE03483.1 - 5.5e-28 97.7 0.0 4.1e-27 94.8 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EGE03483.1 - 1.7e-06 28.2 0.0 4.2e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MRP-S26 PF14943.6 EGE03484.1 - 0.055 13.4 9.7 0.065 13.1 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Med15 PF09606.10 EGE03484.1 - 0.056 12.1 9.8 0.054 12.2 9.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CPSF100_C PF13299.6 EGE03484.1 - 0.24 11.6 8.0 0.28 11.3 8.0 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DHHW PF14286.6 EGE03484.1 - 0.57 9.5 2.3 0.54 9.5 2.3 1.0 1 0 0 1 1 1 0 DHHW protein RNA_pol_Rpc4 PF05132.14 EGE03484.1 - 0.58 10.6 4.8 0.68 10.4 4.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2807 PF10988.8 EGE03484.1 - 0.6 9.9 4.4 0.89 9.3 4.4 1.2 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF853 PF05872.12 EGE03484.1 - 0.84 8.2 7.9 1 7.9 7.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SET PF00856.28 EGE03484.1 - 0.84 10.0 3.4 0.9 9.9 3.4 1.1 1 0 0 1 1 1 0 SET domain Endonuc_Holl PF10107.9 EGE03484.1 - 0.87 9.4 5.2 1.1 9.1 5.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF935 PF06074.12 EGE03484.1 - 1 8.0 13.2 1.1 7.9 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) eIF3_subunit PF08597.10 EGE03484.1 - 1.3 8.9 15.5 1.4 8.8 15.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.12 EGE03484.1 - 1.7 8.4 7.7 1.8 8.4 7.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 EGE03484.1 - 1.8 9.0 9.1 2.3 8.7 9.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex PepSY_TM PF03929.16 EGE03484.1 - 2 8.0 5.3 2.2 7.9 5.3 1.1 1 0 0 1 1 1 0 PepSY-associated TM region DUF4407 PF14362.6 EGE03484.1 - 2.1 7.6 16.3 2.5 7.4 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4615 PF15393.6 EGE03484.1 - 2.2 8.8 6.6 3 8.4 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) XRN_M PF17846.1 EGE03484.1 - 2.2 7.1 6.7 2.4 7.0 6.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 EGE03484.1 - 4.1 6.1 6.1 4.3 6.0 6.1 1.0 1 0 0 1 1 1 0 Presenilin Spore_III_AF PF09581.10 EGE03484.1 - 5.7 6.9 6.5 6.5 6.7 6.5 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Kei1 PF08552.11 EGE03484.1 - 8.6 6.2 9.0 10 6.0 9.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 APH PF01636.23 EGE03485.1 - 0.00051 20.0 0.1 0.0011 19.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Presenilin PF01080.17 EGE03485.1 - 0.69 8.6 1.6 0.99 8.1 1.6 1.1 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 EGE03486.1 - 2.3e-08 33.8 0.9 6.4e-08 32.4 0.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGE03486.1 - 6.8e-07 29.0 0.5 1.8e-06 27.7 0.5 1.7 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 EGE03486.1 - 0.1 12.7 0.6 6.6 7.1 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.27 EGE03487.1 - 7.8e-60 198.8 1.7 2.7e-21 75.3 0.2 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein SpoIIP PF07454.11 EGE03488.1 - 0.075 12.5 6.1 0.13 11.7 6.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) AAT PF03417.16 EGE03488.1 - 0.19 11.4 5.0 0.39 10.4 5.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF4407 PF14362.6 EGE03488.1 - 0.35 10.2 8.9 0.63 9.3 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 EGE03488.1 - 0.91 8.4 18.1 0.031 13.3 11.5 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5523 PF17661.1 EGE03488.1 - 5.8 6.5 17.8 0.035 13.8 9.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) KAR9 PF08580.10 EGE03489.1 - 1.2e-229 764.5 0.0 1.2e-229 764.5 0.0 2.5 2 1 0 2 2 2 1 Yeast cortical protein KAR9 CDC45 PF02724.14 EGE03490.1 - 1.1 7.5 5.9 1.5 7.1 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.20 EGE03491.1 - 1.9e-35 121.9 0.0 3.3e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE03491.1 - 5.7e-07 29.6 0.1 2e-06 27.9 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGE03491.1 - 0.0023 18.1 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EGE03491.1 - 0.087 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Acylphosphatase PF00708.18 EGE03493.1 - 1.8e-17 63.5 0.1 2.1e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.17 EGE03494.1 - 9.6e-99 329.3 0.0 1.2e-98 329.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase adh_short_C2 PF13561.6 EGE03495.1 - 5.5e-52 176.6 0.0 7.5e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE03495.1 - 4.8e-46 156.7 0.0 6.4e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE03495.1 - 7.5e-08 32.5 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EGE03495.1 - 0.013 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 EGE03495.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 EGE03495.1 - 0.022 14.2 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGE03495.1 - 0.043 13.3 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MBOAT PF03062.19 EGE03498.1 - 3e-45 155.1 14.6 3.3e-34 118.8 6.9 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family FA_desaturase PF00487.24 EGE03499.1 - 8e-29 101.2 22.8 1.2e-28 100.6 22.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGE03499.1 - 3.6e-07 30.2 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Laps PF10169.9 EGE03499.1 - 0.47 11.0 4.5 0.8 10.3 4.5 1.2 1 0 0 1 1 1 0 Learning-associated protein zf-HIT PF04438.16 EGE03502.1 - 3.5e-10 39.5 7.2 5.3e-10 39.0 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger Dopey_N PF04118.14 EGE03503.1 - 1.6e-119 398.6 0.0 1.2e-118 395.8 0.0 2.4 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.14 EGE03504.1 - 7.8e-76 255.7 0.1 7.2e-43 147.2 0.2 2.0 1 1 1 2 2 2 2 Trafficking protein Mon1 DEAD PF00270.29 EGE03505.1 - 5.6e-22 78.3 0.0 1.3e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03505.1 - 3.9e-21 75.5 0.7 3e-17 63.0 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.10 EGE03505.1 - 5.2e-15 55.2 0.0 1.2e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EGE03505.1 - 1.2e-13 51.5 8.7 1.2e-13 51.5 8.7 2.3 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 EGE03505.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 EGE03505.1 - 3.1e-06 27.3 0.0 9.8e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 EGE03506.1 - 1.4e-32 111.7 0.2 1.4e-32 111.7 0.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EGE03506.1 - 5.8e-26 90.3 11.9 4.4e-10 39.4 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGE03506.1 - 1e-24 86.2 10.3 2.9e-09 37.0 0.1 6.5 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE03506.1 - 4.7e-16 58.4 5.6 0.00019 21.6 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EGE03506.1 - 6.5e-16 57.9 3.8 8e-06 25.7 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EGE03506.1 - 1.8e-14 53.0 4.0 1.1e-05 24.9 0.1 4.9 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGE03506.1 - 2.6e-11 43.0 6.2 0.0013 18.7 0.0 6.1 6 1 0 6 6 6 2 Kelch motif Pyridoxal_deC PF00282.19 EGE03507.1 - 2.3e-24 85.8 0.0 1.3e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_61 PF03443.14 EGE03508.1 - 0.00031 20.7 0.0 0.0036 17.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3973 PF13119.6 EGE03510.1 - 2.3 8.4 7.3 13 6.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) Beta-lactamase PF00144.24 EGE03511.1 - 2.1e-52 178.4 0.0 3e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EGE03511.1 - 1.8e-06 28.3 0.0 9.3e-06 26.1 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3471) EST1_DNA_bind PF10373.9 EGE03512.1 - 3.9e-06 26.6 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain DUF4642 PF15484.6 EGE03515.1 - 0.018 15.3 0.0 0.023 15.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) NucS PF01939.16 EGE03516.1 - 0.00049 19.5 0.0 0.0007 19.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease NucS STE2 PF02116.15 EGE03517.1 - 2.2e-93 312.6 29.3 2.6e-93 312.4 29.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Metallophos PF00149.28 EGE03518.1 - 2.5e-08 34.7 0.2 3.7e-08 34.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kdo PF06293.14 EGE03520.1 - 3.1e-08 33.2 0.0 0.0035 16.7 0.0 3.1 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE03520.1 - 3.4e-08 33.7 0.0 0.006 16.5 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGE03520.1 - 8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGE03520.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGE03520.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.22 EGE03520.1 - 0.022 14.3 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 0 RIO1 family Choline_kinase PF01633.20 EGE03520.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.21 EGE03521.1 - 1.7e-13 50.4 0.0 2.5e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 EGE03522.1 - 8.1e-53 178.2 1.9 9.7e-53 177.9 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EGE03522.1 - 0.056 14.2 0.2 0.1 13.3 0.2 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EGE03523.1 - 5.4e-64 215.5 0.0 7.6e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Tropomyosin_1 PF12718.7 EGE03524.1 - 0.0011 19.2 29.6 0.0011 19.2 29.6 5.4 5 2 1 6 6 6 1 Tropomyosin like Filament PF00038.21 EGE03524.1 - 0.079 12.5 54.2 0.21 11.1 34.1 4.1 1 1 1 2 2 2 0 Intermediate filament protein TSC22 PF01166.18 EGE03524.1 - 0.079 13.3 0.2 0.079 13.3 0.2 5.7 6 2 2 8 8 8 0 TSC-22/dip/bun family MscS_porin PF12795.7 EGE03524.1 - 3.6 7.1 57.9 0.014 14.9 40.2 3.8 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 EGE03524.1 - 7.5 7.1 19.5 12 6.4 5.0 4.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein N2227 PF07942.12 EGE03525.1 - 3e-60 203.7 0.0 3.9e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EGE03525.1 - 0.0049 16.7 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 EGE03527.1 - 1.2e-17 65.3 0.0 1.6e-17 64.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE03527.1 - 2.7e-05 23.5 0.1 0.00023 20.5 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EGE03527.1 - 0.0046 16.0 0.0 0.059 12.4 0.0 2.0 1 1 1 2 2 2 1 Chlorophyllase Chlorophyllase2 PF12740.7 EGE03527.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme COPIIcoated_ERV PF07970.12 EGE03528.1 - 5.1e-32 111.5 0.0 1e-31 110.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGE03528.1 - 3.5e-23 81.8 0.0 5.9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 EGE03529.1 - 7.5e-53 179.6 0.0 1e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03529.1 - 4.2e-19 68.8 0.0 7.2e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EGE03529.1 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 ABC1 family Pex24p PF06398.11 EGE03530.1 - 1.8e-82 277.3 0.1 2.5e-82 276.8 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EGE03530.1 - 0.0016 16.9 0.0 0.0028 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Nop16 PF09420.10 EGE03532.1 - 2.8e-67 226.8 15.7 3.3e-67 226.6 15.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF3283 PF11686.8 EGE03532.1 - 0.44 10.4 5.0 0.13 12.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) RR_TM4-6 PF06459.12 EGE03532.1 - 8.2 6.2 12.2 0.49 10.2 6.2 1.8 1 1 0 2 2 2 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 EGE03533.1 - 6.2e-59 199.9 10.2 3.8e-58 197.3 10.2 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Anp1 PF03452.14 EGE03534.1 - 6.9e-82 274.8 0.2 9.6e-75 251.4 0.0 2.1 1 1 1 2 2 2 2 Anp1 Glycos_transf_2 PF00535.26 EGE03534.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Mito_carr PF00153.27 EGE03535.1 - 2.3e-44 149.3 0.3 1.4e-15 56.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 EGE03537.1 - 6e-58 193.4 2.1 1.5e-10 41.5 0.0 7.1 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE03537.1 - 4.8e-46 154.2 11.8 5.8e-11 42.4 0.1 10.6 5 2 8 13 13 13 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE03537.1 - 1.3e-44 150.0 4.0 1.2e-06 28.9 0.1 11.1 5 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE03537.1 - 3.2e-40 131.5 6.3 0.0006 20.1 0.0 13.9 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 EGE03537.1 - 8e-34 114.6 15.4 0.011 16.1 0.1 13.0 14 0 0 14 14 14 10 Ankyrin repeat Chorismate_bind PF00425.18 EGE03538.1 - 5.6e-86 288.3 0.0 8.8e-86 287.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EGE03538.1 - 1.2e-36 126.3 0.0 1.8e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EGE03538.1 - 1.9e-09 37.9 0.0 4.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EGE03538.1 - 9.7e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 MFS_1 PF07690.16 EGE03539.1 - 2e-36 125.7 26.8 3e-36 125.1 26.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EGE03539.1 - 4.7e-06 26.2 1.6 4.7e-06 26.2 1.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DHDPS PF00701.22 EGE03542.1 - 2e-41 141.6 0.0 2.3e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2014 PF09427.10 EGE03543.1 - 2.8e-102 341.6 0.2 3.8e-102 341.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EGE03543.1 - 6.1e-18 64.5 1.8 1.3e-17 63.5 1.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EGE03543.1 - 0.11 13.0 1.1 0.17 12.3 0.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EGE03543.1 - 0.55 10.4 3.5 0.54 10.4 2.0 1.7 2 0 0 2 2 2 0 bZIP transcription factor E1-E2_ATPase PF00122.20 EGE03544.1 - 4.3e-40 137.2 14.3 1.4e-31 109.4 0.0 3.8 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE03544.1 - 1e-26 93.8 4.1 1e-26 93.8 4.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGE03544.1 - 3.1e-19 70.1 0.3 9e-16 58.8 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE03544.1 - 2.2e-13 49.7 0.1 2.4e-12 46.4 0.1 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGE03544.1 - 8.1e-12 45.1 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGE03544.1 - 1.7e-05 24.7 1.5 1.7e-05 24.7 1.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EGE03544.1 - 0.0072 16.2 0.9 0.024 14.5 0.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Pro-kuma_activ PF09286.11 EGE03548.1 - 1.4e-35 122.6 0.0 2.3e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGE03548.1 - 1.9e-08 33.9 0.1 3.9e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 Subtilase family NAD_kinase PF01513.21 EGE03549.1 - 1.8e-80 270.3 0.0 2.8e-80 269.7 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAO PF01266.24 EGE03550.1 - 1.2e-32 113.9 0.1 1.6e-29 103.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EGE03550.1 - 0.048 12.8 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGE03550.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GAF_2 PF13185.6 EGE03551.1 - 1.3e-11 45.0 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EGE03551.1 - 5.6e-06 27.0 0.0 6.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain DEAD PF00270.29 EGE03552.1 - 1.4e-35 122.7 0.6 5.5e-35 120.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03552.1 - 6.9e-24 84.3 0.1 2.3e-23 82.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGE03552.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 EGE03552.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SH3_9 PF14604.6 EGE03553.1 - 1.3e-24 85.8 0.9 3.5e-12 46.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EGE03553.1 - 4.2e-18 65.4 2.0 6.5e-18 64.8 0.2 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 EGE03553.1 - 1.1e-15 57.3 5.2 1.7e-15 56.6 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 EGE03553.1 - 3.1e-15 55.5 0.2 1.5e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGE03553.1 - 4.8e-06 26.2 0.1 0.00086 18.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain C1_2 PF03107.16 EGE03553.1 - 0.046 14.1 5.3 0.083 13.2 5.3 1.4 1 0 0 1 1 1 0 C1 domain SH3_3 PF08239.11 EGE03553.1 - 0.05 13.9 0.4 0.56 10.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain FapA PF03961.13 EGE03553.1 - 1.9 7.0 7.3 0.54 8.8 1.1 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Glyco_hydro_72 PF03198.14 EGE03554.1 - 6.4e-138 459.3 3.5 7.6e-138 459.0 3.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGE03554.1 - 2e-07 30.7 0.4 7.4e-07 28.9 0.4 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Arf PF00025.21 EGE03555.1 - 9.5e-74 246.6 0.1 1.1e-73 246.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGE03555.1 - 5.6e-14 52.4 0.0 7.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGE03555.1 - 1.4e-11 44.1 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGE03555.1 - 2.1e-10 40.4 0.0 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGE03555.1 - 2.4e-10 40.1 0.3 3.3e-06 26.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGE03555.1 - 2.7e-08 33.5 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGE03555.1 - 2.2e-06 27.7 0.0 4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGE03555.1 - 0.00029 20.4 0.0 0.025 14.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGE03555.1 - 0.006 16.1 0.5 0.026 14.1 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 EGE03555.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Actin PF00022.19 EGE03556.1 - 3.8e-27 94.9 0.0 2.2e-15 56.2 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EGE03556.1 - 1e-05 24.5 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 EGE03556.1 - 0.00011 21.6 1.0 0.33 10.1 0.1 2.9 3 0 0 3 3 3 2 Putative actin-like family FtsA PF14450.6 EGE03556.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.8 2 1 0 2 2 2 0 Cell division protein FtsA Paf1 PF03985.13 EGE03557.1 - 1.2e-42 146.5 0.2 1.4e-23 83.6 0.1 2.1 1 1 1 2 2 2 2 Paf1 LON_substr_bdg PF02190.16 EGE03558.1 - 3e-23 82.8 0.0 4.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EGE03558.1 - 1.3e-12 47.4 21.9 5.6e-11 42.1 9.0 2.9 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE03558.1 - 1.3e-12 47.5 28.0 1.9e-08 34.1 3.4 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGE03558.1 - 2e-10 40.6 22.2 9.6e-06 25.7 7.4 3.2 2 2 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGE03558.1 - 5.6e-10 39.4 24.8 2.7e-08 34.0 8.5 2.9 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EGE03558.1 - 8.5e-09 35.2 24.7 4.1e-07 29.9 7.7 2.8 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE03558.1 - 1.5e-08 34.4 22.2 9.1e-07 28.7 9.1 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE03558.1 - 4.1e-07 29.8 7.2 4.1e-07 29.8 7.2 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGE03558.1 - 5e-05 23.4 7.2 5e-05 23.4 7.2 2.6 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 EGE03558.1 - 9.2e-05 22.5 1.7 0.012 15.8 0.2 3.1 3 0 0 3 3 3 1 U-box domain Prok-RING_4 PF14447.6 EGE03558.1 - 0.00012 21.8 20.3 0.00047 20.0 7.2 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EGE03558.1 - 0.0011 18.6 6.8 0.0011 18.6 6.8 2.6 2 0 0 2 2 2 1 P-11 zinc finger zf-rbx1 PF12678.7 EGE03558.1 - 0.0026 18.0 3.2 0.0026 18.0 3.2 2.7 2 1 1 3 3 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGE03558.1 - 0.021 14.6 18.5 0.027 14.3 6.1 3.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EGE03558.1 - 0.89 9.5 8.3 1.2 9.1 1.2 2.5 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.8 EGE03558.1 - 4.1 7.3 13.2 0.069 13.0 4.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RICTOR_N PF14664.6 EGE03559.1 - 7e-129 430.0 0.2 1.3e-128 429.2 0.2 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EGE03559.1 - 5.2e-38 129.8 0.1 2.9e-36 124.2 0.0 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EGE03559.1 - 6.1e-37 125.6 1.6 6.1e-34 115.9 0.2 4.7 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EGE03559.1 - 3.7e-29 100.8 1.7 1.5e-26 92.4 0.1 4.1 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EGE03559.1 - 9.3e-14 51.3 12.4 2.9e-13 49.7 12.4 1.9 1 0 0 1 1 1 1 Hr1 repeat DLP_helical PF18709.1 EGE03559.1 - 0.059 12.6 2.2 0.11 11.6 2.2 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain Arm PF00514.23 EGE03559.1 - 1.5 9.0 5.3 51 4.1 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Uricase PF01014.18 EGE03560.1 - 5.1e-74 246.7 0.7 4.4e-40 137.0 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 EGE03560.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.18 EGE03561.1 - 3e-42 143.8 0.0 3.7e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 PDZ_6 PF17820.1 EGE03561.1 - 0.065 13.1 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Ribosomal_S9 PF00380.19 EGE03562.1 - 1.8e-31 109.2 0.2 2e-31 109.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.11 EGE03563.1 - 2.5e-96 323.2 0.0 2.9e-96 323.0 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein DUF4604 PF15377.6 EGE03563.1 - 0.2 12.1 2.7 0.22 11.9 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Ribosomal_S11 PF00411.19 EGE03564.1 - 2.2e-46 156.8 1.1 2.7e-46 156.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EGE03564.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 EGE03565.1 - 1.3e-14 53.8 0.0 2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EGE03565.1 - 2e-06 28.3 0.0 4.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGE03565.1 - 1.1e-05 25.7 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EGE03565.1 - 0.0027 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGE03565.1 - 0.0028 17.3 0.0 0.005 16.5 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EGE03565.1 - 0.021 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EGE03565.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EGE03565.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain CDH-cyt PF16010.5 EGE03566.1 - 5.7e-16 58.7 0.6 2e-15 56.9 0.6 1.8 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EGE03566.1 - 8.4e-09 35.7 12.8 8.4e-09 35.7 12.8 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 UAA PF08449.11 EGE03566.1 - 0.016 14.4 1.6 0.028 13.6 1.3 1.6 1 1 0 1 1 1 0 UAA transporter family DOMON PF03351.17 EGE03566.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 DOMON domain DUF2427 PF10348.9 EGE03566.1 - 0.062 13.1 8.5 0.035 13.9 4.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4083 PF13314.6 EGE03566.1 - 0.2 11.6 0.4 13 5.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) RRM_occluded PF16842.5 EGE03567.1 - 0.0023 17.7 0.3 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Paf67 PF10255.9 EGE03568.1 - 5.7e-159 529.4 0.0 6.7e-159 529.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EGE03568.1 - 0.026 14.6 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EGE03568.1 - 0.082 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Fe-S_biosyn PF01521.20 EGE03569.1 - 2.3e-10 40.7 0.0 1.4e-08 34.9 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.23 EGE03570.1 - 7.8e-11 42.7 0.3 1.4e-10 41.9 0.3 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain UvrD_C PF13361.6 EGE03570.1 - 0.064 12.6 0.1 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Aminotran_5 PF00266.19 EGE03572.1 - 2.1e-07 30.2 0.0 6.5e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGE03572.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1788 PF08747.11 EGE03572.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) DUF1077 PF06417.12 EGE03573.1 - 2.3e-50 169.5 2.5 2.9e-50 169.2 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) TMEM171 PF15471.6 EGE03573.1 - 0.12 11.3 5.5 0.22 10.5 5.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Methyltransf_2 PF00891.18 EGE03574.1 - 8.2e-25 87.3 0.0 1.2e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGE03574.1 - 0.092 12.6 0.0 0.86 9.4 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Cnd3 PF12719.7 EGE03574.1 - 0.1 11.8 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DUF3754 PF12576.8 EGE03575.1 - 9.2 6.2 6.1 1.2 9.1 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) Adaptin_N PF01602.20 EGE03577.1 - 4.4e-115 385.2 7.2 5.5e-115 384.9 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGE03577.1 - 3.5e-56 189.7 9.8 1.5e-55 187.6 1.1 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGE03577.1 - 3.9e-13 49.6 6.5 2.5e-08 34.2 0.4 4.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EGE03577.1 - 9.5e-10 37.9 4.3 0.021 15.1 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 EGE03577.1 - 0.00095 19.2 0.1 16 5.6 0.0 4.3 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGE03577.1 - 0.001 19.0 4.6 3.9 7.6 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGE03577.1 - 0.0016 18.1 2.0 0.59 9.6 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 EGE03577.1 - 0.0018 18.8 7.0 0.88 10.1 0.1 5.7 6 1 1 7 7 7 1 HEAT-like repeat Importin_rep_4 PF18808.1 EGE03577.1 - 0.13 12.5 0.1 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Importin repeat SH3_1 PF00018.28 EGE03578.1 - 4.8e-10 38.9 0.1 9.4e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGE03578.1 - 5.4e-10 38.8 0.1 1.6e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGE03578.1 - 5.7e-09 35.7 0.1 1.6e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain DNA_pol_phi PF04931.13 EGE03578.1 - 4.1 5.4 6.8 7 4.6 6.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 EGE03579.1 - 5e-24 84.4 0.1 7.8e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 EGE03580.1 - 8e-46 154.9 2.2 3.9e-45 152.7 2.2 1.8 1 1 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 EGE03581.1 - 5.9e-117 391.3 0.1 6.7e-117 391.1 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.23 EGE03582.1 - 5.4e-131 436.9 0.3 5.4e-131 436.9 0.3 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGE03582.1 - 1.6e-69 234.5 0.2 3.3e-69 233.5 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGE03582.1 - 2e-68 229.4 6.8 6.9e-62 208.1 2.0 4.4 3 0 0 3 3 3 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGE03582.1 - 1.2e-40 137.9 2.7 7.5e-40 135.3 0.1 3.8 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EGE03582.1 - 5.7e-17 61.9 10.5 0.00019 21.7 0.0 9.4 8 2 1 9 9 8 3 HEAT repeats HEAT PF02985.22 EGE03582.1 - 9.6e-15 53.4 18.6 0.0023 18.0 0.1 12.4 13 0 0 13 13 12 1 HEAT repeat HEAT_EZ PF13513.6 EGE03582.1 - 1.1e-14 54.6 11.7 0.0026 18.2 0.1 11.1 11 1 2 13 13 12 4 HEAT-like repeat FATC PF02260.20 EGE03582.1 - 1.3e-14 53.7 0.3 4.4e-14 52.0 0.3 2.0 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 EGE03582.1 - 6.8e-09 36.0 0.3 0.87 9.6 0.0 6.7 4 2 3 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGE03582.1 - 4.1e-08 32.2 5.6 0.016 13.8 0.1 5.3 3 2 2 5 5 5 2 Adaptin N terminal region UME PF08064.13 EGE03582.1 - 2.6e-05 24.1 7.1 7.4 6.5 0.0 6.9 6 2 0 6 6 6 1 UME (NUC010) domain MMS19_C PF12460.8 EGE03582.1 - 0.0004 19.6 11.2 0.029 13.5 0.1 4.8 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EGE03582.1 - 0.00046 19.8 0.2 20 4.7 0.0 5.2 5 1 0 5 5 5 0 CLASP N terminal Tti2 PF10521.9 EGE03582.1 - 0.0024 17.5 1.1 5.8 6.4 0.0 4.7 3 1 3 6 6 6 1 Tti2 family IFRD PF05004.13 EGE03582.1 - 0.019 14.1 0.3 0.64 9.1 0.1 3.2 2 1 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Sec7_N PF12783.7 EGE03582.1 - 0.082 12.8 2.4 3.7 7.4 0.0 4.7 5 1 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EGE03582.1 - 0.089 13.0 0.5 40 4.4 0.0 5.2 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_14 PF13428.6 EGE03582.1 - 0.15 12.9 9.7 9.6 7.3 0.0 5.4 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGE03582.1 - 0.24 11.1 3.6 2.4 7.9 0.0 3.7 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 EGE03582.1 - 0.37 11.3 2.1 15 6.2 0.0 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EGE03584.1 - 8.5e-10 38.7 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03584.1 - 3.8e-08 33.9 0.0 7.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE03584.1 - 8.1e-08 32.9 0.0 1.3e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03584.1 - 9.9e-08 32.5 0.0 4.1e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE03584.1 - 8.6e-06 25.6 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 EGE03584.1 - 3.4e-05 23.8 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DREV PF05219.12 EGE03584.1 - 0.039 13.1 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EGE03584.1 - 0.041 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pam16 PF03656.13 EGE03585.1 - 1.3e-35 122.1 0.2 1.6e-35 121.9 0.2 1.0 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.11 EGE03586.1 - 6.2e-97 324.9 0.6 7.9e-97 324.5 0.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DAHP_synth_1 PF00793.20 EGE03589.1 - 1.2e-101 339.2 0.0 1.4e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF2458 PF10454.9 EGE03590.1 - 1.6e-66 223.2 1.8 2.1e-66 222.8 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Ribosomal_L50 PF10501.9 EGE03592.1 - 3.6e-18 65.7 0.0 7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.27 EGE03592.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 SAP domain Rtf2 PF04641.12 EGE03593.1 - 7.6e-62 209.0 0.2 9.3e-62 208.8 0.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EGE03593.1 - 1.8e-09 37.3 0.0 0.00051 19.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGE03593.1 - 0.00043 20.2 0.4 0.0025 17.8 0.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-NOSIP PF15906.5 EGE03593.1 - 0.00093 19.3 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EGE03593.1 - 0.0073 16.2 0.2 0.016 15.1 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGE03593.1 - 0.027 14.3 0.1 0.074 12.9 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGE03593.1 - 0.043 13.7 0.7 0.57 10.1 0.3 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGE03593.1 - 0.12 12.7 0.8 0.24 11.8 0.2 1.8 2 0 0 2 2 2 0 Ring finger domain PRKCSH-like PF12999.7 EGE03594.1 - 3.7e-45 153.9 10.5 2.5e-41 141.4 10.5 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGE03594.1 - 5.9e-30 104.0 0.5 1.6e-29 102.6 0.5 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EGE03594.1 - 3.1e-09 37.7 0.9 3.1e-09 37.7 0.9 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EGE03594.1 - 0.01 15.7 2.5 0.023 14.6 2.5 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 HMG_box PF00505.19 EGE03594.1 - 0.013 15.9 2.2 0.032 14.6 2.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Ax_dynein_light PF10211.9 EGE03594.1 - 0.02 14.8 9.4 0.045 13.7 9.4 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain DUF3450 PF11932.8 EGE03594.1 - 0.14 11.4 11.0 0.4 10.0 9.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 EGE03594.1 - 0.28 10.5 9.8 0.46 9.8 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 EGE03594.1 - 0.32 11.1 5.3 0.075 13.1 1.4 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation CorA PF01544.18 EGE03594.1 - 0.5 9.6 3.4 0.92 8.8 3.4 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Taxilin PF09728.9 EGE03594.1 - 1.4 8.1 15.9 2.4 7.2 15.9 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Nas2_N PF18265.1 EGE03594.1 - 1.4 8.9 3.4 20 5.2 0.1 2.5 2 0 0 2 2 2 0 Nas2 N_terminal domain HIF-1a_CTAD PF08778.10 EGE03595.1 - 0.14 11.8 0.1 1.4 8.6 0.0 2.4 3 0 0 3 3 3 0 HIF-1 alpha C terminal transactivation domain NTP_transf_2 PF01909.23 EGE03596.1 - 2e-11 44.0 0.0 4.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGE03596.1 - 4.2e-11 42.9 0.0 8.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGE03596.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Aldo_ket_red PF00248.21 EGE03597.1 - 2.3e-67 227.3 0.0 2.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 EGE03598.1 - 1.4e-25 90.1 26.3 2e-24 86.4 22.6 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily COX14 PF14880.6 EGE03599.1 - 4.9e-18 64.7 0.0 4.9e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly HetR_C PF18460.1 EGE03599.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain Methyltransf_23 PF13489.6 EGE03600.1 - 2.5e-20 73.0 0.0 3.9e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03600.1 - 6.6e-10 39.6 0.0 2.4e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE03600.1 - 9.1e-09 35.9 0.0 2.8e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE03600.1 - 1.7e-06 27.9 0.0 1.3e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE03600.1 - 4.2e-06 27.4 0.0 1.5e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE03600.1 - 0.00048 19.5 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGE03600.1 - 0.035 13.9 0.0 0.089 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EGE03600.1 - 0.036 13.4 0.0 0.097 12.0 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DUF4897 PF16238.5 EGE03600.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) HP_OMP_2 PF02521.14 EGE03600.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein HAD_2 PF13419.6 EGE03601.1 - 4.7e-26 91.9 0.0 5.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE03601.1 - 3.3e-15 56.9 0.0 9.9e-14 52.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGE03601.1 - 6.2e-10 39.8 0.0 1.8e-09 38.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE03601.1 - 8.5e-09 35.4 0.2 2.3e-08 34.0 0.0 1.8 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGE03601.1 - 1.7e-07 31.2 0.0 0.00019 21.5 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE03601.1 - 0.004 16.9 0.0 0.14 11.9 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EGE03601.1 - 0.0084 16.0 0.1 2.4 8.0 0.0 2.9 3 0 0 3 3 3 1 Acid Phosphatase Acid_phosphat_B PF03767.14 EGE03601.1 - 0.091 12.3 0.0 0.46 10.0 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M35 PF02102.15 EGE03603.1 - 6.4e-101 337.8 0.8 7.4e-101 337.6 0.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGE03603.1 - 7.6e-42 143.3 4.0 1.3e-41 142.5 4.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_hydro_32N PF00251.20 EGE03603.1 - 0.0079 15.8 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Actin PF00022.19 EGE03604.1 - 8e-142 472.6 0.0 9e-142 472.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGE03604.1 - 0.064 12.1 0.0 13 4.5 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein ATG22 PF11700.8 EGE03605.1 - 2.1e-199 663.1 14.4 2.4e-199 662.9 14.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGE03605.1 - 9.7e-07 28.0 48.4 0.0017 17.3 26.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EGE03605.1 - 0.0018 16.9 5.4 0.0018 16.9 5.4 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein Mpp10 PF04006.12 EGE03606.1 - 7.6e-111 371.5 61.7 1.8e-109 366.9 61.7 2.0 1 1 0 1 1 1 1 Mpp10 protein RepA_C PF04796.12 EGE03606.1 - 0.22 11.5 0.1 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 Plasmid encoded RepA protein HJURP_mid PF12346.8 EGE03606.1 - 0.27 11.7 4.2 1.4 9.4 1.9 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat Methyltransf_16 PF10294.9 EGE03607.1 - 3e-46 157.3 0.0 3.9e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGE03607.1 - 0.0018 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGE03607.1 - 0.0045 16.4 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EGE03607.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CI-B14_5a PF07347.12 EGE03608.1 - 0.085 12.7 0.2 0.22 11.4 0.0 1.8 2 1 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.21 EGE03609.1 - 6.1e-22 77.8 0.0 9.2e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGE03609.1 - 4.2e-12 46.0 0.0 6.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGE03609.1 - 0.0053 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Spore_coat_CotO PF14153.6 EGE03609.1 - 0.22 11.4 15.3 15 5.4 17.8 2.0 2 0 0 2 2 2 0 Spore coat protein CotO Zip PF02535.22 EGE03609.1 - 0.93 8.6 1.7 0.99 8.6 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 EGE03609.1 - 1.3 8.0 12.8 1.7 7.6 12.8 1.1 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.8 EGE03609.1 - 2.3 7.0 14.7 3.3 6.5 14.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.14 EGE03609.1 - 2.7 7.7 15.5 4.3 7.1 15.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein VIR_N PF15912.5 EGE03609.1 - 4.3 6.9 9.7 5.7 6.5 9.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CDC27 PF09507.10 EGE03609.1 - 6.6 6.0 21.5 8 5.7 21.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CCDC53 PF10152.9 EGE03609.1 - 9.1 6.7 10.8 16 5.9 10.8 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CH PF00307.31 EGE03610.1 - 2e-63 211.4 0.0 4.4e-20 71.9 0.1 5.2 4 1 1 5 5 5 5 Calponin homology (CH) domain EF-hand_7 PF13499.6 EGE03610.1 - 1.2e-07 32.1 1.5 2e-06 28.1 0.6 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGE03610.1 - 8.6e-05 22.2 0.9 0.012 15.5 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGE03610.1 - 0.00019 20.7 2.2 0.61 9.8 0.1 3.7 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.8 EGE03610.1 - 0.00039 20.2 0.0 0.58 10.0 0.0 3.8 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_5 PF13202.6 EGE03610.1 - 0.42 10.2 1.8 3.6 7.2 0.1 2.7 2 0 0 2 2 2 0 EF hand Hydantoinase_B PF02538.14 EGE03611.1 - 4.3e-214 711.7 0.0 6.5e-214 711.1 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGE03611.1 - 7.5e-102 340.5 0.5 7.5e-102 340.5 0.5 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGE03611.1 - 4.3e-60 202.5 1.1 1.2e-58 197.7 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region PC4 PF02229.16 EGE03612.1 - 6.7e-24 83.3 0.1 1e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) MIT PF04212.18 EGE03613.1 - 4.2e-14 52.4 0.8 8.5e-14 51.4 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Ubiq_cyt_C_chap PF03981.12 EGE03614.1 - 9.9e-34 116.4 0.3 1.6e-33 115.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M24 PF00557.24 EGE03616.1 - 6.8e-57 192.5 0.0 8.8e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGE03616.1 - 1.5e-23 82.9 0.0 2.8e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TIP41 PF04176.13 EGE03618.1 - 9.2e-71 236.8 0.0 1.1e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 EGE03619.1 - 5e-70 235.9 0.0 6.2e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03619.1 - 1.5e-42 145.7 0.0 1.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE03619.1 - 2.7e-07 30.2 0.0 3.7e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGE03619.1 - 0.00014 21.3 0.2 0.00022 20.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGE03619.1 - 0.0019 17.2 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGE03619.1 - 0.02 14.5 0.1 0.08 12.5 0.0 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 EGE03619.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGE03619.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGE03619.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_M76 PF09768.9 EGE03620.1 - 6.2e-71 237.7 2.5 7.4e-71 237.4 2.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGE03620.1 - 0.00089 19.1 0.7 0.0021 17.9 0.4 1.6 1 1 1 2 2 2 1 SprT-like family Peptidase_M91 PF14891.6 EGE03620.1 - 0.009 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Effector protein CAF20 PF17052.5 EGE03620.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Cap associated factor Tox-MPTase2 PF15638.6 EGE03620.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PALP PF00291.25 EGE03621.1 - 2.2e-35 122.5 0.1 2.8e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FIST PF08495.10 EGE03621.1 - 0.039 14.0 0.3 0.16 12.0 0.3 2.1 1 1 0 1 1 1 0 FIST N domain ACP_syn_III_C PF08541.10 EGE03621.1 - 0.19 11.9 0.4 60 3.9 0.0 3.4 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SRPRB PF09439.10 EGE03622.1 - 2.5e-26 92.2 0.2 9.1e-25 87.1 0.2 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGE03622.1 - 3.1e-07 30.0 0.0 0.00081 18.9 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE03622.1 - 0.00021 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE03622.1 - 0.0083 16.5 0.3 0.018 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EGE03622.1 - 0.014 15.0 0.7 0.25 10.9 0.7 2.1 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Roc PF08477.13 EGE03622.1 - 0.046 13.9 0.0 0.47 10.7 0.1 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGE03622.1 - 0.053 13.3 0.3 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGE03622.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGE03622.1 - 0.072 12.9 0.3 11 5.6 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EGE03622.1 - 0.095 12.6 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Gtr1_RagA PF04670.12 EGE03622.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGE03622.1 - 0.14 12.4 0.5 0.32 11.3 0.5 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE03622.1 - 0.15 11.9 0.1 0.62 9.9 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase GPI-anchored PF10342.9 EGE03623.1 - 5.5e-10 39.9 0.1 1.3e-09 38.7 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 EGE03623.1 - 1.6e-09 38.4 3.8 2.9e-09 37.6 3.8 1.3 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 EGE03624.1 - 4.2e-42 144.4 2.6 5.7e-42 144.0 2.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase PF00069.25 EGE03625.1 - 1.9e-41 142.2 0.0 3e-40 138.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03625.1 - 3.6e-23 82.2 0.0 5.5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE03625.1 - 0.036 14.0 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Condensation PF00668.20 EGE03627.1 - 1.2e-123 413.2 0.0 4.7e-41 140.9 0.0 4.7 5 0 0 5 5 5 4 Condensation domain AMP-binding PF00501.28 EGE03627.1 - 5.8e-69 232.7 0.0 1.2e-35 123.0 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EGE03627.1 - 2.2e-39 133.6 11.9 4.6e-10 39.7 0.2 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site DUF1524 PF07510.11 EGE03627.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) AMP-binding PF00501.28 EGE03628.1 - 2.7e-143 477.6 0.0 1.5e-72 244.5 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGE03628.1 - 7.4e-48 163.4 0.0 8.4e-30 103.8 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE03628.1 - 2.6e-17 62.9 0.5 3.9e-08 33.5 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE03628.1 - 7.1e-13 49.3 0.0 3.2e-06 28.0 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EGE03628.1 - 0.15 11.8 0.0 24 4.6 0.0 2.3 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain K_oxygenase PF13434.6 EGE03629.1 - 2.7e-95 319.4 0.0 1e-93 314.3 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGE03629.1 - 0.0004 20.4 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DHHC PF01529.20 EGE03630.1 - 8e-36 123.1 10.9 8e-36 123.1 10.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGE03630.1 - 8.5e-29 100.0 0.0 6.7e-10 39.4 0.0 3.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE03630.1 - 9.2e-23 80.0 0.1 5.2e-07 29.8 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE03630.1 - 3e-22 76.3 2.4 1.4e-07 31.2 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EGE03630.1 - 7.6e-20 71.0 1.8 2.8e-06 27.8 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EGE03630.1 - 1.1e-19 69.9 0.0 8.3e-07 29.2 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat OB_NTP_bind PF07717.16 EGE03631.1 - 1.5e-21 76.5 0.0 3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold PWI PF01480.17 EGE03631.1 - 5e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain T2SSE PF00437.20 EGE03631.1 - 0.0036 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGE03631.1 - 0.0053 17.0 0.0 0.037 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGE03631.1 - 0.014 15.9 0.0 0.014 15.9 0.0 2.8 2 2 1 3 3 3 0 ABC transporter AAA_23 PF13476.6 EGE03631.1 - 0.049 14.1 0.0 0.049 14.1 0.0 3.5 1 1 2 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGE03631.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EGE03631.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Cyt-b5 PF00173.28 EGE03632.1 - 1.1e-20 73.6 0.1 1.2e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4430 PF14478.6 EGE03632.1 - 0.077 13.6 0.1 0.11 13.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4430) V-ATPase_H_C PF11698.8 EGE03632.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H DUF4291 PF14124.6 EGE03633.1 - 1.2e-72 243.6 0.1 1.4e-72 243.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.7 EGE03634.1 - 4.4e-46 156.0 0.9 5.8e-46 155.6 0.0 1.7 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EGE03634.1 - 0.0048 17.4 13.3 0.0049 17.3 12.0 1.6 1 1 0 1 1 1 1 Fez1 DUF3584 PF12128.8 EGE03634.1 - 0.13 9.7 12.4 0.18 9.3 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EGE03634.1 - 0.32 11.1 17.5 0.63 10.1 8.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EGE03634.1 - 0.39 10.5 2.3 0.74 9.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Lebercilin PF15619.6 EGE03634.1 - 0.79 9.3 11.4 1.4 8.6 11.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AMP-binding PF00501.28 EGE03636.1 - 1e-72 245.1 0.0 1.4e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGE03636.1 - 1.2e-15 57.2 0.1 2.7e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGE03636.1 - 5e-15 56.2 0.1 1.7e-14 54.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 EGE03637.1 - 3.3e-50 169.8 0.5 7.1e-49 165.5 0.5 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGE03637.1 - 4.1e-18 65.7 0.1 8.8e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE03637.1 - 0.00022 20.8 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family SUIM_assoc PF16619.5 EGE03637.1 - 0.0075 16.3 1.6 0.017 15.2 1.6 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 AAA_16 PF13191.6 EGE03637.1 - 0.089 13.2 0.3 0.19 12.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGE03637.1 - 0.12 11.6 0.6 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Septin RsgA_GTPase PF03193.16 EGE03637.1 - 0.14 12.1 0.0 9.5 6.1 0.0 2.6 2 1 1 3 3 3 0 RsgA GTPase AAA_25 PF13481.6 EGE03637.1 - 0.14 11.7 0.1 0.34 10.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGE03637.1 - 0.15 11.6 0.2 2.6 7.5 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B MFS_1 PF07690.16 EGE03638.1 - 2.6e-35 122.0 33.7 3.7e-35 121.5 33.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SH PF01445.17 EGE03638.1 - 0.018 15.0 0.0 0.069 13.1 0.0 2.0 1 0 0 1 1 1 0 Viral small hydrophobic protein SHMT PF00464.19 EGE03640.1 - 4.7e-196 651.1 0.0 5.4e-196 650.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Mor PF08765.11 EGE03640.1 - 0.052 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Mor transcription activator family MOSC PF03473.17 EGE03641.1 - 2.3e-34 118.2 0.0 3.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGE03641.1 - 6.4e-13 48.6 0.0 1.9e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF2235 PF09994.9 EGE03642.1 - 7.5e-92 307.7 0.0 9.2e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mg_trans_NIPA PF05653.14 EGE03644.1 - 3.9e-88 295.4 29.0 5.5e-88 294.9 29.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGE03644.1 - 3.6e-05 24.0 6.1 3.6e-05 24.0 6.1 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF5362 PF17319.2 EGE03644.1 - 0.11 12.4 5.0 0.75 9.7 0.2 3.4 2 1 0 3 3 3 0 Family of unknown function (DUF5362) DUF1435 PF07256.12 EGE03644.1 - 0.33 11.1 2.1 0.39 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1435) PTCB-BRCT PF12738.7 EGE03645.1 - 3.5e-05 23.7 0.4 0.00014 21.7 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EGE03645.1 - 0.0064 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGE03645.1 - 0.14 12.5 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain KilA-N PF04383.13 EGE03647.1 - 0.0005 19.9 0.0 0.0081 16.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.23 EGE03652.1 - 5.7e-16 58.7 0.0 1.4e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGE03652.1 - 2.4e-13 50.4 0.0 5.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE03652.1 - 1.9e-11 44.1 0.1 4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE03652.1 - 1.3e-07 32.0 0.2 2.8e-06 27.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGE03652.1 - 0.0019 18.8 1.5 0.0034 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EGE03652.1 - 0.0037 16.6 0.0 0.015 14.6 0.0 1.9 1 1 1 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 EGE03652.1 - 0.0079 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGE03652.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 EGE03652.1 - 0.053 12.9 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 EGE03652.1 - 0.054 14.0 0.1 0.35 11.4 0.0 2.4 2 1 0 2 2 2 0 ABC transporter RuvA_C PF07499.13 EGE03652.1 - 0.18 12.3 1.3 1.6 9.2 0.1 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Gcn1_N PF12074.8 EGE03653.1 - 4.9e-114 381.3 4.1 5.4e-114 381.2 0.2 3.4 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EGE03653.1 - 5.1e-29 97.8 38.6 0.092 13.1 0.1 22.3 24 0 0 24 24 23 7 HEAT repeat HEAT_2 PF13646.6 EGE03653.1 - 2.5e-21 75.9 36.3 1.6e-05 25.2 0.0 13.3 10 3 6 16 16 14 8 HEAT repeats HEAT_EZ PF13513.6 EGE03653.1 - 6.4e-20 71.2 43.1 3.8e-07 30.5 0.0 18.5 23 0 0 23 23 17 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGE03653.1 - 1.7e-12 47.7 0.0 0.24 12.0 0.0 8.1 6 1 2 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGE03653.1 - 1.8e-11 44.4 14.6 0.012 15.7 0.2 8.7 7 2 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EGE03653.1 - 2.5e-07 31.0 6.7 0.18 11.9 0.0 6.8 6 1 1 7 7 7 2 Parkin co-regulated protein TIP120 PF08623.10 EGE03653.1 - 7.1e-07 29.1 1.0 0.01 15.6 0.0 6.1 6 0 0 6 6 6 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 EGE03653.1 - 1.1e-06 28.4 0.1 1.6 8.3 0.0 6.7 5 1 1 6 6 6 1 CLASP N terminal DUF937 PF06078.11 EGE03653.1 - 0.00054 20.6 1.5 6.6 7.3 0.0 5.3 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF937) Adaptin_N PF01602.20 EGE03653.1 - 0.0007 18.3 15.5 1.3 7.5 0.5 6.2 6 1 1 7 7 7 3 Adaptin N terminal region RasGEF_N_2 PF14663.6 EGE03653.1 - 0.055 13.9 0.9 16 5.9 0.0 4.6 4 0 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pes-10 PF07149.11 EGE03653.1 - 0.059 12.4 0.1 0.16 11.0 0.1 1.7 1 0 0 1 1 1 0 Pes-10 FANCI_S2 PF14676.6 EGE03653.1 - 1.1 9.5 7.6 22 5.3 0.1 4.7 5 0 0 5 5 4 0 FANCI solenoid 2 IFRD PF05004.13 EGE03653.1 - 1.2 8.2 23.2 0.58 9.2 0.1 6.6 7 0 0 7 7 7 0 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 EGE03653.1 - 1.5 8.3 10.2 19 4.7 0.0 5.8 7 1 1 8 8 8 0 Tti2 family RTP1_C1 PF10363.9 EGE03653.1 - 2.6 8.3 10.3 61 3.9 0.0 6.5 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_L19e PF01280.20 EGE03654.1 - 3.2e-62 208.9 6.9 3.2e-62 208.9 6.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF4239 PF14023.6 EGE03654.1 - 0.12 12.1 1.4 0.21 11.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TRAP-gamma PF07074.12 EGE03654.1 - 0.19 11.3 3.5 0.25 10.9 3.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Zn_clus PF00172.18 EGE03661.1 - 1.3e-09 38.0 11.0 2.3e-09 37.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N_NLPC_P60 PF12912.7 EGE03662.1 - 0.039 14.3 1.4 2.1 8.8 0.0 2.1 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term adh_short PF00106.25 EGE03663.1 - 6.4e-36 123.6 0.1 9e-36 123.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE03663.1 - 1.2e-27 97.0 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE03663.1 - 4.3e-09 36.5 2.2 4.6e-07 29.9 3.1 2.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EGE03663.1 - 3.8e-05 23.3 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGE03663.1 - 0.0047 16.1 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.13 EGE03663.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DUF3216 PF11505.8 EGE03663.1 - 0.2 11.9 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) CorA PF01544.18 EGE03665.1 - 1e-39 136.6 0.5 2.5e-39 135.4 0.5 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.7 EGE03666.1 - 2.4e-137 458.4 0.5 2.4e-137 458.4 0.5 1.4 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DUF3824 PF12868.7 EGE03668.1 - 0.00022 21.9 35.8 0.00022 21.9 35.8 3.5 2 2 1 3 3 3 1 Domain of unknwon function (DUF3824) Amidohydro_1 PF01979.20 EGE03669.1 - 1.6e-18 67.2 2.0 2.2e-18 66.7 2.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGE03669.1 - 1.9e-13 50.7 4.4 1.1e-11 44.9 0.9 2.2 1 1 1 2 2 2 2 Amidohydrolase family Abhydrolase_1 PF00561.20 EGE03670.1 - 8e-22 78.1 0.0 1.7e-18 67.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE03670.1 - 5.7e-19 69.6 0.2 7.1e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE03670.1 - 1.4e-18 67.1 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EGE03670.1 - 2e-05 23.4 0.0 2.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EGE03670.1 - 0.00032 20.9 0.1 0.00056 20.1 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGE03670.1 - 0.032 14.0 0.9 1.5 8.5 0.8 2.3 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 EGE03671.1 - 3.6e-15 55.7 1.2 7.8e-15 54.6 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE03671.1 - 6.1e-08 32.7 5.3 1.1e-07 31.8 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxogl_dehyd_N PF16078.5 EGE03671.1 - 0.0065 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Spore_YpjB PF09577.10 EGE03671.1 - 0.078 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Ribosomal_L44 PF00935.19 EGE03672.1 - 5.7e-36 122.8 12.1 9e-36 122.2 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 EGE03672.1 - 0.74 10.2 4.7 0.15 12.4 1.2 1.6 2 0 0 2 2 2 0 Cathelicidin ubiquitin PF00240.23 EGE03673.1 - 6.8e-24 83.4 0.0 7.6e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGE03673.1 - 4.1e-13 48.9 0.0 4.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGE03673.1 - 9.9e-05 22.7 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGE03673.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ferritin_2 PF13668.6 EGE03674.1 - 2.9e-17 63.1 0.0 4.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain PilN PF05137.13 EGE03674.1 - 0.041 14.0 0.2 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) Rav1p_C PF12234.8 EGE03675.1 - 4.1e-283 940.6 0.0 5.8e-283 940.1 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Nup160 PF11715.8 EGE03675.1 - 0.6 8.7 4.8 2.6 6.6 0.2 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 EGE03675.1 - 2.5 9.1 16.8 20 6.2 0.5 5.9 6 1 1 7 7 7 0 WD domain, G-beta repeat OPT PF03169.15 EGE03676.1 - 8.9e-162 539.9 20.0 1e-161 539.7 20.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_9 PF14604.6 EGE03677.1 - 3.5e-08 33.2 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGE03677.1 - 4.1e-06 26.3 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGE03677.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 EGE03677.1 - 0.00029 21.0 2.0 0.00039 20.6 0.1 2.1 2 0 0 2 2 2 1 Podoplanin Pup PF05639.11 EGE03677.1 - 0.92 10.5 2.3 1.4 9.8 0.0 2.5 2 0 0 2 2 2 0 Pup-like protein Apt1 PF10351.9 EGE03677.1 - 2.5 6.9 3.5 3.4 6.4 3.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 EGE03677.1 - 4.9 5.7 15.2 0.42 9.2 3.1 2.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 EGE03679.1 - 1.9e-36 125.8 0.0 2.8e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03679.1 - 1.4e-13 50.8 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE03679.1 - 0.0033 16.3 0.0 0.0052 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE03679.1 - 0.0061 16.5 0.1 0.022 14.7 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE03679.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EGE03679.1 - 0.018 14.7 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGE03679.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family KIX_2 PF16987.5 EGE03679.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 KIX domain muHD PF10291.9 EGE03680.1 - 1.4e-74 250.9 0.0 2e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EGE03680.1 - 3.2e-08 33.7 0.2 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.12 EGE03680.1 - 0.085 12.9 5.0 0.058 13.4 2.5 2.1 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.11 EGE03680.1 - 1.3 7.9 5.4 2.2 7.1 5.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Peptidase_M20 PF01546.28 EGE03681.1 - 4.6e-27 95.1 0.4 1.5e-26 93.4 0.1 1.9 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGE03681.1 - 2.6e-18 65.9 0.0 8.2e-18 64.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGE03681.1 - 0.0014 18.3 0.0 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 MAD PF05557.13 EGE03682.1 - 6.3e-59 200.0 75.0 1.5e-50 172.3 76.1 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein CC2-LZ PF16516.5 EGE03682.1 - 0.13 12.6 0.1 0.13 12.6 0.1 9.1 4 2 2 6 6 6 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YojJ PF10372.9 EGE03682.1 - 1.2 9.3 6.8 1.1 9.4 0.4 4.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Arginosuc_synth PF00764.19 EGE03683.1 - 6.8e-150 499.7 0.0 8e-150 499.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EGE03683.1 - 0.0025 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGE03683.1 - 0.021 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_114 PF03537.13 EGE03683.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 DUF2624 PF11116.8 EGE03683.1 - 0.17 12.8 0.0 0.4 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DNA_pol3_gamma3 PF12169.8 EGE03683.1 - 0.17 11.8 0.1 0.48 10.3 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Asn_synthase PF00733.21 EGE03683.1 - 0.2 11.3 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase RasGEF PF00617.19 EGE03685.1 - 5.4e-42 144.0 0.3 8.4e-42 143.4 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGE03685.1 - 1.5e-13 50.9 0.1 3.7e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.19 EGE03686.1 - 8.6e-30 103.1 1.1 8.6e-30 103.1 1.1 2.0 2 0 0 2 2 2 1 DIL domain Ank_2 PF12796.7 EGE03686.1 - 1.2e-13 51.5 0.1 7.3e-13 48.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE03686.1 - 1.1e-09 38.4 0.0 5.9e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGE03686.1 - 5.4e-09 36.1 0.7 0.0063 16.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EGE03686.1 - 9.5e-08 32.5 0.5 0.00029 21.3 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE03686.1 - 1.2e-06 28.4 1.4 0.011 16.1 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeat DUF4407 PF14362.6 EGE03689.1 - 0.022 14.1 1.7 0.023 14.0 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HEAT PF02985.22 EGE03690.1 - 1.1e-15 56.3 4.6 0.00043 20.3 0.1 7.6 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 EGE03690.1 - 1.4e-14 54.2 3.5 1e-05 25.9 0.0 8.2 8 1 1 9 9 9 3 HEAT-like repeat HEAT_2 PF13646.6 EGE03690.1 - 1.5e-13 50.9 3.4 0.00032 21.0 0.0 5.9 5 2 1 6 6 6 3 HEAT repeats IFRD PF05004.13 EGE03690.1 - 1.1e-08 34.5 1.5 0.00092 18.4 0.1 4.3 2 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 EGE03690.1 - 1.2e-06 28.6 0.5 1.1 9.3 0.0 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGE03690.1 - 3.8e-06 26.3 0.4 3.7e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 EGE03690.1 - 2.1e-05 24.4 1.3 0.00015 21.6 0.2 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EGE03690.1 - 2.8e-05 24.6 0.0 1.5 9.4 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGE03690.1 - 0.0012 18.5 1.3 0.099 12.2 0.0 3.9 4 1 0 4 4 4 1 CLASP N terminal RIX1 PF08167.12 EGE03690.1 - 0.0067 16.2 0.1 0.23 11.2 0.0 3.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EGE03690.1 - 0.0072 16.5 0.4 2.1 8.6 0.0 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 EGE03690.1 - 0.0087 16.2 0.1 0.041 14.0 0.1 2.2 2 0 0 2 2 2 1 Parkin co-regulated protein Ecm29 PF13001.7 EGE03690.1 - 0.0091 14.7 0.5 0.14 10.8 0.0 2.8 1 1 0 2 2 2 1 Proteasome stabiliser UNC45-central PF11701.8 EGE03690.1 - 0.0092 16.0 0.1 0.048 13.6 0.1 2.3 1 1 0 1 1 1 1 Myosin-binding striated muscle assembly central Adaptin_N PF01602.20 EGE03690.1 - 0.034 12.7 0.7 7.8 4.9 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region Cohesin_HEAT PF12765.7 EGE03690.1 - 0.084 13.2 0.0 0.49 10.8 0.0 2.4 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion NPC1_N PF16414.5 EGE03691.1 - 4.1e-83 278.7 6.6 6.1e-83 278.1 6.6 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EGE03691.1 - 1.2e-59 202.3 6.8 5.1e-57 193.6 6.8 2.8 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EGE03691.1 - 9.1e-35 119.8 0.2 9.1e-35 119.8 0.2 4.2 3 2 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGE03691.1 - 8.2e-06 25.0 6.9 8.2e-06 25.0 6.9 3.1 3 2 0 3 3 3 1 MMPL family Folate_rec PF03024.14 EGE03691.1 - 0.00024 21.0 2.7 0.00054 19.9 2.7 1.6 1 0 0 1 1 1 1 Folate receptor family DUF2433 PF10360.9 EGE03692.1 - 1.2e-48 164.3 0.0 2.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EGE03692.1 - 0.00075 20.0 0.0 0.0018 18.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE03692.1 - 0.0011 19.2 0.0 0.0042 17.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIA PF03153.13 EGE03692.1 - 0.45 10.5 10.9 0.87 9.5 10.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 EGE03693.1 - 8.8e-90 302.1 50.1 7.4e-87 292.5 40.5 4.1 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 EGE03693.1 - 5.1e-08 32.9 9.1 1.1e-07 31.8 9.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 EGE03693.1 - 0.00062 20.3 0.3 0.0014 19.2 0.3 1.6 1 0 0 1 1 1 1 SlyX DUF16 PF01519.16 EGE03693.1 - 0.0068 16.9 1.1 0.013 16.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 COG7 PF10191.9 EGE03693.1 - 0.055 11.7 0.1 0.084 11.1 0.1 1.2 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) SHE3 PF17078.5 EGE03693.1 - 0.11 12.1 3.1 0.19 11.4 3.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EGE03693.1 - 0.18 12.4 10.1 0.44 11.1 10.1 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.18 EGE03693.1 - 0.27 11.6 0.9 0.59 10.5 0.9 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Tudor_3 PF18115.1 EGE03694.1 - 2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGE03694.1 - 0.0041 17.2 0.0 0.0072 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_2 PF18104.1 EGE03694.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.8 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain TRAUB PF08164.12 EGE03695.1 - 1.1e-30 106.0 0.0 4.2e-30 104.1 0.0 2.1 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EGE03695.1 - 1.2e-26 94.1 0.9 1.2e-26 94.1 0.9 2.2 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor KfrA_N PF11740.8 EGE03695.1 - 0.059 14.0 1.7 0.11 13.2 0.1 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term ParA PF10609.9 EGE03696.1 - 1.6e-81 273.4 0.0 1.4e-79 267.1 0.0 2.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGE03696.1 - 1.2e-12 48.0 0.0 4.3e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGE03696.1 - 9.1e-10 38.7 0.2 9.8e-08 32.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EGE03696.1 - 2.2e-06 27.2 0.1 3.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGE03696.1 - 0.0002 20.6 0.5 0.0018 17.5 0.3 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EGE03696.1 - 0.0024 17.5 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EGE03696.1 - 0.031 13.7 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 EGE03696.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein DUF2614 PF11023.8 EGE03696.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Abhydrolase_3 PF07859.13 EGE03697.1 - 3.7e-13 49.8 0.0 4.7e-06 26.6 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold IHABP4_N PF16174.5 EGE03697.1 - 0.95 10.1 5.9 2.8 8.5 4.1 2.4 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Tht1 PF04163.12 EGE03698.1 - 1.7e-07 30.4 11.9 5.9e-07 28.6 8.6 2.7 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein ApoLp-III PF07464.11 EGE03698.1 - 0.0072 16.4 1.6 0.0072 16.4 1.6 2.5 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Spore_IV_A PF09547.10 EGE03698.1 - 0.016 14.1 0.3 0.025 13.5 0.3 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) RNA_pol_Rpb4 PF03874.16 EGE03698.1 - 1.1 9.5 4.4 1.4 9.3 0.3 2.4 1 1 1 2 2 2 0 RNA polymerase Rpb4 Syntaxin_2 PF14523.6 EGE03698.1 - 1.2 9.5 12.6 8.1 6.9 4.5 3.5 2 1 1 3 3 3 0 Syntaxin-like protein Peptidase_U4 PF03419.13 EGE03698.1 - 1.3 8.3 8.8 2 7.7 8.8 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Ribosomal_L6 PF00347.23 EGE03699.1 - 4.3e-20 72.2 0.0 1.9e-09 38.0 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 EGE03700.1 - 3.4e-36 125.2 1.6 1.7e-30 106.5 0.1 2.0 2 0 0 2 2 2 2 Inositol monophosphatase family VHS PF00790.19 EGE03701.1 - 3e-26 92.0 0.0 5.4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain ENTH PF01417.20 EGE03701.1 - 0.00017 21.6 0.1 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Swm2 PF17083.5 EGE03701.1 - 0.024 14.6 0.1 0.12 12.4 0.0 2.2 2 1 0 2 2 2 0 Nucleolar protein Swm2 GAT PF03127.14 EGE03701.1 - 0.048 14.0 0.4 0.14 12.5 0.4 1.9 1 0 0 1 1 1 0 GAT domain RPN7 PF10602.9 EGE03701.1 - 0.052 13.2 1.4 0.098 12.4 1.4 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 CCDC106 PF15794.5 EGE03701.1 - 5.9 6.5 10.6 1.2 8.8 5.2 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 adh_short_C2 PF13561.6 EGE03702.1 - 5.8e-34 117.7 0.6 2.5e-32 112.3 0.6 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE03702.1 - 2.5e-25 89.1 2.9 1.1e-20 74.0 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase FHA PF00498.26 EGE03702.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 FHA domain ADH_zinc_N PF00107.26 EGE03702.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.10 EGE03702.1 - 4.5 7.1 9.5 3.5 7.5 1.8 2.7 2 1 0 2 2 2 0 KR domain Hva1_TUDOR PF11160.8 EGE03703.1 - 2.6e-19 69.1 0.2 3e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CP2 PF04516.15 EGE03704.1 - 3.5e-67 226.1 0.0 5.1e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor DEAD PF00270.29 EGE03705.1 - 3.8e-44 150.6 0.1 8.8e-44 149.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03705.1 - 1.1e-26 93.3 0.0 4.1e-26 91.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03705.1 - 5.2e-07 29.8 0.1 1.6e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EGE03705.1 - 2.5e-05 23.2 0.1 0.0014 17.5 0.0 2.4 1 1 1 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EGE03705.1 - 0.01 16.1 0.6 0.13 12.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain SIKE PF05769.11 EGE03705.1 - 0.078 12.9 1.8 0.59 10.0 0.3 2.6 3 0 0 3 3 3 0 SIKE family DUF2514 PF10721.9 EGE03705.1 - 2 8.5 0.0 2 8.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2514) Ank_2 PF12796.7 EGE03706.1 - 1.4e-50 169.8 0.0 1.4e-13 51.2 0.0 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EGE03706.1 - 1.7e-28 97.8 0.0 2.6e-05 24.4 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGE03706.1 - 4e-27 91.3 0.0 6.3e-05 23.1 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EGE03706.1 - 1.8e-25 89.0 0.0 9.3e-09 35.7 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE03706.1 - 2.5e-18 65.9 0.0 0.00056 20.2 0.0 5.5 1 1 4 5 5 5 5 Ankyrin repeats (many copies) NACHT_N PF17100.5 EGE03706.1 - 1.9e-13 50.8 0.1 4.8e-13 49.5 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 EGE03706.1 - 3.6e-07 30.7 0.0 1.2e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGE03706.1 - 5.8e-05 23.1 0.0 0.00025 21.0 0.0 2.1 2 1 0 2 2 2 1 NACHT domain PEGA PF08308.11 EGE03706.1 - 0.012 15.4 0.1 95 3.0 0.1 4.3 3 1 1 4 4 4 0 PEGA domain KAP_NTPase PF07693.14 EGE03706.1 - 0.048 12.9 0.0 0.13 11.4 0.0 1.6 1 1 1 2 2 2 0 KAP family P-loop domain VWA_3_C PF18571.1 EGE03706.1 - 0.28 11.1 2.6 45 4.0 0.1 4.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain FAD_binding_1 PF00667.20 EGE03707.1 - 4.7e-54 183.3 0.0 6.8e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGE03707.1 - 2.8e-09 37.6 0.0 1.1e-08 35.7 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain BCAS2 PF05700.11 EGE03710.1 - 0.04 13.6 1.7 0.04 13.6 1.7 1.7 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Mvb12 PF09452.10 EGE03710.1 - 0.17 12.3 1.9 1.1 9.7 0.1 2.0 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 DUF5595 PF18077.1 EGE03710.1 - 0.55 10.3 3.2 2.7 8.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Beta-lactamase PF00144.24 EGE03711.1 - 4.9e-28 98.3 0.0 1.2e-27 97.0 0.0 1.5 1 1 1 2 2 2 1 Beta-lactamase PP-binding PF00550.25 EGE03711.1 - 2.2e-07 31.1 0.4 3.2e-06 27.4 0.1 2.6 2 1 1 3 3 3 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 EGE03712.1 - 3.9e-30 104.3 0.0 6.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGE03712.1 - 1.2e-14 54.8 0.0 2.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGE03712.1 - 2.6e-06 28.5 0.0 6.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.21 EGE03712.1 - 1.5e-05 24.7 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EGE03712.1 - 1.7e-05 24.6 0.0 0.0003 20.4 0.0 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 EGE03713.1 - 6.8e-46 156.8 66.7 1.7e-45 155.5 62.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE03713.1 - 1.7e-16 60.2 13.4 1.7e-16 60.2 13.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGE03713.1 - 9e-13 47.5 25.7 3.8e-12 45.4 25.7 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGE03713.1 - 0.076 11.3 17.4 0.031 12.6 1.8 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3522 PF12036.8 EGE03713.1 - 0.11 12.7 5.8 4.9 7.4 5.2 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Proteasome PF00227.26 EGE03714.1 - 9.5e-61 204.6 0.1 1.2e-60 204.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGE03714.1 - 2.6e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EGE03714.1 - 0.012 15.7 0.3 0.03 14.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EGE03714.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.19 EGE03715.1 - 1.9e-11 43.9 7.7 1.5e-09 37.9 0.1 3.7 3 0 0 3 3 3 2 FF domain WW PF00397.26 EGE03715.1 - 1.6e-10 40.9 6.8 3.2e-09 36.7 2.9 2.6 2 0 0 2 2 2 2 WW domain DUF5641 PF18701.1 EGE03715.1 - 0.00055 20.0 1.2 0.0039 17.3 0.7 2.5 2 0 0 2 2 2 1 Family of unknown function (DUF5641) BPL_N PF09825.9 EGE03715.1 - 0.89 8.6 7.6 1.1 8.2 6.7 1.5 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal PIN_12 PF16289.5 EGE03715.1 - 1 9.8 4.7 5.8 7.4 1.1 2.4 1 1 1 2 2 2 0 PIN domain AbiH PF14253.6 EGE03716.1 - 0.04 13.8 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DASH_Dam1 PF08653.10 EGE03716.1 - 0.17 11.7 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 SPOC PF07744.13 EGE03718.1 - 8.1e-25 87.5 0.0 1.6e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EGE03718.1 - 6.3e-21 75.0 0.0 1.6e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EGE03718.1 - 2.9e-10 39.9 11.1 5.1e-10 39.1 11.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EGE03718.1 - 0.011 16.1 1.1 0.059 13.8 1.1 2.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 EGE03718.1 - 0.02 14.5 4.0 0.035 13.7 4.0 1.4 1 0 0 1 1 1 0 PHD-finger Terminase_GpA PF05876.12 EGE03718.1 - 0.63 8.5 6.0 0.98 7.9 6.0 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_10 PF10058.9 EGE03718.1 - 1.6 8.5 5.8 2.9 7.7 5.8 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein LUC7 PF03194.15 EGE03719.1 - 6.6e-73 245.5 0.1 8.2e-73 245.2 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EGE03719.1 - 0.0097 15.0 0.5 0.016 14.3 0.5 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Filament PF00038.21 EGE03719.1 - 0.02 14.5 0.2 0.078 12.6 0.1 1.8 1 1 1 2 2 2 0 Intermediate filament protein DASH_Duo1 PF08651.10 EGE03719.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 PP_kinase_N PF13089.6 EGE03719.1 - 0.14 12.5 0.1 0.51 10.7 0.0 1.9 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain DUF2130 PF09903.9 EGE03719.1 - 0.14 11.4 0.2 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) MCPsignal PF00015.21 EGE03719.1 - 0.17 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 EGE03719.1 - 0.22 11.8 2.5 0.35 11.1 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA GRP PF07172.11 EGE03719.1 - 0.31 11.7 20.1 0.52 11.0 20.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.14 EGE03720.1 - 1.3e-231 770.0 0.0 1.6e-231 769.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component VMA21 PF09446.10 EGE03721.1 - 1.5e-11 44.2 7.2 2e-11 43.8 7.2 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 EGE03722.1 - 2e-26 92.4 0.1 2e-26 92.4 0.1 3.3 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) TFIIA PF03153.13 EGE03722.1 - 6.7 6.6 30.3 3.2 7.6 3.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L35Ae PF01247.18 EGE03723.1 - 3e-43 145.9 0.5 3.4e-43 145.7 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EGE03723.1 - 0.001 19.2 0.0 0.65 10.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain SRF-TF PF00319.18 EGE03724.1 - 1.8e-23 81.8 0.3 2.7e-23 81.2 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.11 EGE03725.1 - 4.3e-170 566.6 0.0 7.1e-170 565.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF45 PF01863.17 EGE03725.1 - 0.039 14.0 1.4 0.095 12.7 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF3602 PF12223.8 EGE03726.1 - 3.9e-25 88.2 11.2 1.6e-22 79.9 3.5 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 EGE03726.1 - 2.2 7.9 12.2 0.81 9.3 0.6 2.7 2 1 1 3 3 3 0 GTP1/OBG YqhR PF11085.8 EGE03729.1 - 0.022 14.7 1.5 0.049 13.6 1.5 1.5 1 0 0 1 1 1 0 Conserved membrane protein YqhR UPF0220 PF05255.11 EGE03729.1 - 0.072 12.6 0.2 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) FAD_binding_4 PF01565.23 EGE03730.1 - 3.5e-17 62.5 1.4 5.8e-17 61.7 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE03730.1 - 0.0043 17.1 0.5 0.01 15.9 0.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like ERG4_ERG24 PF01222.17 EGE03731.1 - 9.7e-147 489.2 17.6 1.1e-146 489.0 17.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_M43 PF05572.13 EGE03732.1 - 5.7e-17 62.0 0.2 1.1e-16 61.1 0.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EGE03732.1 - 4.8e-06 27.1 0.7 4.8e-05 23.9 0.7 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EGE03732.1 - 4e-05 23.8 3.6 0.0001 22.5 3.6 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGE03732.1 - 0.0002 21.0 3.4 0.0017 18.1 1.8 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EGE03732.1 - 0.0055 16.6 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 EGE03732.1 - 0.011 15.6 0.7 0.016 15.1 0.7 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 EGE03732.1 - 0.073 12.7 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 EGE03732.1 - 0.12 12.0 2.6 0.14 11.7 0.8 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF4953 PF16313.5 EGE03732.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Met-zincin KCH PF16944.5 EGE03733.1 - 1.9e-99 332.6 9.9 2.2e-99 332.3 9.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF747 PF05346.11 EGE03734.1 - 2.8e-118 395.0 9.0 3.8e-118 394.6 9.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 EGE03734.1 - 0.3 12.1 2.6 0.48 11.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) p450 PF00067.22 EGE03735.1 - 2.4e-70 237.6 0.0 2.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M20 PF01546.28 EGE03736.1 - 4.2e-21 75.6 0.0 8.2e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EGE03736.1 - 2.2e-14 53.6 14.2 0.017 16.0 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03736.1 - 0.00023 21.4 0.1 2 8.8 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain M20_dimer PF07687.14 EGE03736.1 - 0.00043 20.2 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGE03736.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 MtN3_slv PF03083.16 EGE03737.1 - 0.0062 16.6 0.0 0.0078 16.2 0.0 1.1 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange FolB PF02152.18 EGE03737.1 - 0.11 13.0 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroneopterin aldolase TraQ PF09679.10 EGE03738.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Tim17 PF02466.19 EGE03739.1 - 2e-32 111.9 8.4 2.5e-32 111.6 8.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.18 EGE03740.1 - 1e-35 123.3 0.0 1.2e-34 119.8 0.0 2.2 2 0 0 2 2 2 1 Asparaginase p450 PF00067.22 EGE03741.1 - 1.3e-66 225.3 0.0 1.5e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.22 EGE03742.1 - 7.7e-30 104.2 12.7 1.7e-29 103.0 12.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE03742.1 - 4.4e-17 62.5 0.1 7.8e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Flavoprotein PF02441.19 EGE03743.1 - 1.6e-12 47.4 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 EGE03743.1 - 0.006 17.1 0.2 42 4.9 0.0 4.2 3 1 2 5 5 5 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 EGE03744.1 - 1.7e-45 155.5 45.6 1.7e-45 155.5 45.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE03744.1 - 5.2e-15 55.3 13.5 5.2e-15 55.3 13.5 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter RICTOR_V PF14668.6 EGE03744.1 - 0.028 14.6 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Pox_EPC_I2-L1 PF12575.8 EGE03744.1 - 5.4 7.3 5.4 6.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 MFS_1_like PF12832.7 EGE03744.1 - 7.1 5.4 28.2 0.04 12.8 9.5 2.9 3 1 0 3 3 3 0 MFS_1 like family Cerato-platanin PF07249.12 EGE03745.1 - 5.9e-43 145.8 0.3 7.4e-43 145.4 0.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EGE03745.1 - 0.0056 16.5 0.2 0.0098 15.7 0.2 1.5 1 1 0 1 1 1 1 Barwin family Sulfotransfer_3 PF13469.6 EGE03746.1 - 0.01 16.3 0.0 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Sulfotransferase family D123 PF07065.14 EGE03747.1 - 0.0052 16.0 0.0 0.029 13.5 0.0 1.9 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 EGE03747.1 - 0.028 14.5 0.0 0.097 12.7 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 EGE03747.1 - 0.038 13.9 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF2011 PF09428.10 EGE03749.1 - 3.6e-29 100.8 0.1 1.7e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) TRAP-gamma PF07074.12 EGE03749.1 - 0.88 9.1 2.3 1.4 8.4 2.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LAMTOR PF15454.6 EGE03750.1 - 3.3e-11 43.6 0.3 1.2e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator UQ_con PF00179.26 EGE03752.1 - 7.4e-36 122.9 0.1 9e-36 122.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_P21 PF05313.12 EGE03753.1 - 2.2 7.8 10.3 0.11 12.1 1.3 2.7 3 0 0 3 3 3 0 Poxvirus P21 membrane protein APG12 PF04110.13 EGE03754.1 - 6.1e-27 93.9 0.0 9e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGE03754.1 - 0.037 14.2 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 EGE03755.1 - 2.3e-100 335.3 2.5 2.7e-100 335.1 2.5 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EGE03755.1 - 6e-07 29.2 1.6 1.1e-06 28.3 1.6 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase YjcQ PF09639.10 EGE03755.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 YjcQ protein Dfp1_Him1_M PF08630.10 EGE03756.1 - 1.3e-36 125.6 0.1 1.3e-36 125.6 0.1 2.5 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EGE03756.1 - 1.3e-18 66.9 0.3 1.3e-18 66.9 0.3 1.6 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.7 EGE03756.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 EGE03756.1 - 0.031 14.7 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGE03756.1 - 0.11 12.9 0.0 0.41 11.1 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Peptidase_M24 PF00557.24 EGE03757.1 - 1.2e-52 178.6 0.0 2.4e-52 177.7 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 EGE03757.1 - 1.6e-37 127.9 0.0 2.6e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FR47 PF08445.10 EGE03758.1 - 4.3e-09 36.2 0.1 2e-06 27.7 0.1 2.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGE03758.1 - 3.2e-06 27.9 0.1 1.4e-05 25.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE03758.1 - 8.8e-05 22.7 0.0 0.00043 20.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE03758.1 - 0.073 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE03758.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N PF00107.26 EGE03759.1 - 2.7e-20 72.7 0.0 5.1e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE03759.1 - 7.5e-13 49.7 0.0 1.5e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE03759.1 - 6.4e-07 29.2 0.0 2.7e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyridox_ox_2 PF12900.7 EGE03760.1 - 5.7e-37 126.8 0.0 8.4e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SIR2 PF02146.17 EGE03761.1 - 6.9e-37 127.1 0.0 3.2e-36 124.9 0.0 1.8 1 1 0 1 1 1 1 Sir2 family MFS_1 PF07690.16 EGE03762.1 - 5.3e-38 130.8 20.4 8.8e-21 74.2 5.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGE03762.1 - 1.1e-13 50.6 24.6 2e-05 23.4 7.3 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 EGE03762.1 - 2.8e-07 29.7 19.6 0.00017 20.6 0.8 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EGE03762.1 - 7.9e-05 21.7 21.3 0.00067 18.6 21.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EGE03762.1 - 0.026 12.8 14.1 0.36 9.0 2.1 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3938 PF13074.6 EGE03762.1 - 0.17 12.1 4.2 1.8 8.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Trp_oprn_chp PF09534.10 EGE03762.1 - 0.78 9.5 5.5 16 5.2 5.5 2.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_3 PF05977.13 EGE03762.1 - 1.2 7.5 18.7 0.009 14.4 4.0 2.6 3 0 0 3 3 3 0 Transmembrane secretion effector BT1 PF03092.16 EGE03762.1 - 1.7 6.8 10.8 1.5 7.0 0.0 3.7 4 1 1 5 5 5 0 BT1 family CoA_binding_3 PF13727.6 EGE03762.1 - 7.1 6.6 10.0 0.86 9.6 5.2 1.9 2 0 0 2 2 2 0 CoA-binding domain MFS_1 PF07690.16 EGE03763.1 - 9e-25 87.3 55.0 8.6e-23 80.8 46.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PALP PF00291.25 EGE03764.1 - 1.8e-54 185.2 0.1 2.2e-54 184.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GRDA PF04723.14 EGE03764.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A SNF2_N PF00176.23 EGE03766.1 - 7.3e-67 225.5 0.0 3.4e-65 220.1 0.0 2.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE03766.1 - 9.1e-16 58.2 0.0 3.9e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE03766.1 - 1.1e-05 25.2 0.0 3.8e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGE03766.1 - 8.3e-05 22.7 0.0 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PPV_E1_N PF00524.18 EGE03766.1 - 0.011 16.1 0.6 0.051 14.0 0.6 2.2 1 0 0 1 1 1 0 E1 Protein, N terminal domain Nop25 PF09805.9 EGE03766.1 - 1.9 9.0 18.1 4.2 7.8 5.7 3.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF3736 PF12540.8 EGE03766.1 - 3.2 7.9 11.8 0.44 10.6 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3736) Pkinase PF00069.25 EGE03768.1 - 5e-63 212.9 0.0 6.7e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03768.1 - 3e-33 115.2 0.0 4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE03768.1 - 4.5e-06 26.2 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGE03768.1 - 0.0003 19.7 0.0 0.00047 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE03768.1 - 0.0075 16.2 1.7 0.017 15.1 0.2 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE03768.1 - 0.019 14.3 0.7 0.04 13.3 0.7 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGE03768.1 - 0.061 12.3 0.0 0.083 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Endonuc_Holl PF10107.9 EGE03768.1 - 0.064 13.1 0.2 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Seadorna_VP7 PF07387.11 EGE03768.1 - 0.21 10.6 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3377 PF11857.8 EGE03769.1 - 0.1 12.5 0.9 0.84 9.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) CEND1 PF15677.5 EGE03769.1 - 0.12 12.9 0.8 0.99 9.9 0.0 2.6 2 0 0 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 EphA2_TM PF14575.6 EGE03769.1 - 7.1 7.6 0.0 7.1 7.6 0.0 3.5 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 EGE03770.1 - 0.00016 22.0 0.0 0.00019 21.7 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Collagen PF01391.18 EGE03770.1 - 0.061 13.1 5.1 0.22 11.3 2.4 2.3 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF1310 PF07006.11 EGE03770.1 - 0.13 12.3 0.5 0.18 11.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) CD99L2 PF12301.8 EGE03770.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.0 1 1 0 2 2 2 0 CD99 antigen like protein 2 Zn_peptidase PF04228.13 EGE03770.1 - 0.18 11.2 0.2 0.24 10.8 0.2 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase UPF0029 PF01205.19 EGE03772.1 - 0.32 11.3 2.3 1.5 9.2 2.3 2.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 ATP-synt_D PF01813.17 EGE03775.1 - 0.0044 16.9 1.4 0.22 11.4 1.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit D HTH_37 PF13744.6 EGE03775.1 - 0.045 13.7 1.1 0.14 12.1 0.4 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Med13_C PF06333.12 EGE03776.1 - 9.4e-69 232.2 6.8 9.4e-69 232.2 6.8 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EGE03776.1 - 3.7e-46 158.0 0.9 3.7e-46 158.0 0.9 2.3 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EGE03776.1 - 4.8e-24 85.5 9.1 2.7e-22 79.8 0.3 3.9 3 1 0 3 3 3 1 MID domain of medPIWI NUC153 PF08159.12 EGE03777.1 - 4.7e-10 39.1 1.1 1.1e-09 38.0 1.1 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EGE03777.1 - 8.3e-05 23.3 0.0 8.5 7.4 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE03777.1 - 0.01 16.1 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_4 PF17784.1 EGE03778.1 - 7.7e-74 248.1 0.0 9.4e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGE03778.1 - 0.00016 22.2 0.4 0.016 15.6 0.0 2.5 1 1 1 2 2 2 2 Sulfotransferase family Lipase3_N PF03893.16 EGE03778.1 - 0.11 12.5 0.1 4.5 7.4 0.0 2.7 3 0 0 3 3 3 0 Lipase 3 N-terminal region SET PF00856.28 EGE03780.1 - 9.3e-15 55.4 1.3 5.1e-14 53.0 0.0 2.8 2 2 0 2 2 2 1 SET domain TPR_8 PF13181.6 EGE03780.1 - 0.00056 19.9 0.7 0.0091 16.1 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE03780.1 - 0.00088 19.2 4.9 0.042 14.0 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE03780.1 - 0.0014 18.9 1.8 0.0041 17.4 1.8 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE03780.1 - 0.0038 17.9 0.0 0.029 15.2 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE03780.1 - 0.017 14.9 3.2 0.33 10.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PDZ_6 PF17820.1 EGE03780.1 - 0.048 13.5 0.0 14 5.6 0.0 2.9 3 0 0 3 3 3 0 PDZ domain TPR_16 PF13432.6 EGE03780.1 - 0.23 12.1 3.9 1.9 9.2 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 EGE03781.1 - 1e-26 93.3 0.5 2e-26 92.4 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE03781.1 - 4.8e-05 23.4 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ATG13 PF10033.9 EGE03782.1 - 5.9e-67 225.9 0.0 8.7e-67 225.3 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.18 EGE03784.1 - 1.3e-23 83.4 0.1 6.2e-07 29.9 0.0 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGE03784.1 - 1.7e-12 47.5 0.2 9.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 EGE03784.1 - 4.7e-10 39.0 4.5 9.1e-09 34.9 0.1 4.1 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EGE03784.1 - 8e-06 26.3 0.1 0.00022 21.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE03784.1 - 0.0032 17.8 0.0 0.082 13.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE03784.1 - 0.0081 16.7 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE03784.1 - 0.016 15.7 0.1 2 9.3 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat TCO89 PF10452.9 EGE03785.1 - 0.021 13.9 17.4 0.076 12.0 0.0 3.4 2 2 0 2 2 2 0 TORC1 subunit TCO89 PBP1_TM PF14812.6 EGE03785.1 - 0.19 12.1 4.5 2.5 8.5 0.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VHS PF00790.19 EGE03786.1 - 2e-42 144.4 3.1 7.9e-42 142.5 0.4 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EGE03786.1 - 8.4e-16 57.9 1.8 1.5e-15 57.1 1.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EGE03786.1 - 9.5e-07 28.3 10.5 0.0014 18.4 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EGE03786.1 - 1.2e-05 25.5 0.3 8.6e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 GAT domain Npa1 PF11707.8 EGE03786.1 - 0.016 14.6 0.2 0.038 13.3 0.2 1.6 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DUF753 PF05444.12 EGE03786.1 - 0.059 13.4 1.2 0.099 12.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF753) FYVE_2 PF02318.16 EGE03786.1 - 0.069 13.4 0.3 0.17 12.1 0.3 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 EGE03786.1 - 1.8 8.6 5.2 1.7 8.7 3.6 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Fer4_2 PF12797.7 EGE03786.1 - 3.5 7.9 4.3 2.2 8.6 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 EGE03787.1 - 3e-53 180.9 0.1 4.5e-53 180.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE03787.1 - 1.9e-17 63.8 0.6 2.2e-14 53.8 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EGE03787.1 - 0.00014 22.4 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain HSP70 PF00012.20 EGE03788.1 - 1.3e-259 862.5 12.9 1.5e-259 862.3 12.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGE03788.1 - 2.8e-19 69.1 0.8 5.5e-18 64.9 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EGE03788.1 - 0.0024 16.9 0.5 0.03 13.3 0.4 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EGE03788.1 - 0.01 15.1 1.6 0.95 8.7 0.2 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGE03788.1 - 0.016 14.7 0.1 0.74 9.3 0.0 2.6 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 EGE03788.1 - 0.089 12.5 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 EGE03788.1 - 0.21 10.8 2.9 0.9 8.7 0.6 2.6 2 1 0 2 2 2 0 StbA protein FtsA PF14450.6 EGE03788.1 - 0.65 10.5 8.0 8.4 6.9 0.2 3.5 3 2 0 3 3 3 0 Cell division protein FtsA FIVAR PF07554.13 EGE03788.1 - 2 9.2 8.9 3.3 8.5 1.2 3.8 4 0 0 4 4 4 0 FIVAR domain GTP_EFTU PF00009.27 EGE03789.1 - 7e-50 169.3 0.0 1.6e-49 168.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EGE03789.1 - 1.8e-19 69.8 8.1 3.9e-19 68.7 8.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EGE03789.1 - 1.6e-08 34.8 1.7 2.6e-08 34.1 0.0 2.4 3 0 0 3 3 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGE03789.1 - 8.7e-08 32.4 0.0 4.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGE03789.1 - 9.6e-08 32.1 0.0 2.9e-06 27.3 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGE03789.1 - 0.0001 21.8 0.1 0.03 13.8 0.0 2.5 1 1 1 2 2 2 2 ADP-ribosylation factor family Ras PF00071.22 EGE03789.1 - 0.00076 19.1 0.2 0.017 14.7 0.0 2.3 1 1 1 2 2 2 1 Ras family FeoB_N PF02421.18 EGE03789.1 - 0.00087 18.9 0.2 0.052 13.1 0.2 3.2 3 1 0 3 3 3 1 Ferrous iron transport protein B SRPRB PF09439.10 EGE03789.1 - 0.0022 17.4 0.1 0.4 10.1 0.1 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGE03789.1 - 0.0035 17.3 0.4 0.49 10.3 0.2 2.5 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EGE03789.1 - 0.0055 16.1 0.1 0.011 15.1 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGE03789.1 - 0.0068 16.6 0.1 2.9 8.1 0.0 2.8 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGE03789.1 - 0.017 14.3 0.4 0.89 8.6 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit GramPos_pilinD1 PF16555.5 EGE03789.1 - 0.76 9.9 13.4 0.4 10.8 1.9 2.5 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain Cyt-b5 PF00173.28 EGE03790.1 - 5.7e-24 84.1 0.1 7.4e-24 83.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain K_trans PF02705.16 EGE03791.1 - 3.7e-185 616.5 17.3 4.3e-185 616.2 17.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter VHS PF00790.19 EGE03792.1 - 1.6e-36 125.2 1.5 2.8e-36 124.5 1.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EGE03792.1 - 1.1e-17 63.4 0.1 7.5e-17 60.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGE03792.1 - 3e-15 55.8 0.1 6e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGE03792.1 - 3.8e-13 48.9 0.1 1.1e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EGE03792.1 - 4.2e-10 39.8 1.5 4.2e-10 39.8 1.5 2.4 2 1 0 2 2 2 1 GAT domain DUF4598 PF15370.6 EGE03792.1 - 0.00094 19.6 1.5 0.0025 18.3 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) UIM PF02809.20 EGE03792.1 - 0.022 14.7 1.4 0.052 13.5 1.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3361 PF11841.8 EGE03792.1 - 0.53 10.2 2.3 0.44 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) CemA PF03040.14 EGE03792.1 - 1.5 8.7 4.3 4.4 7.2 0.2 2.3 2 0 0 2 2 2 0 CemA family Pkinase PF00069.25 EGE03793.1 - 1.3e-71 241.1 0.1 2.4e-71 240.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03793.1 - 1e-44 152.8 0.5 1.7e-44 152.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGE03793.1 - 1.1e-21 76.9 0.5 1.1e-21 76.9 0.5 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGE03793.1 - 3.7e-07 29.3 1.1 1.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGE03793.1 - 2e-06 27.3 0.0 3.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGE03793.1 - 0.031 13.7 1.0 0.046 13.1 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE03793.1 - 0.041 13.8 0.1 0.56 10.1 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 EGE03793.1 - 0.056 13.1 0.6 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 DSHCT (NUC185) domain Haspin_kinase PF12330.8 EGE03793.1 - 0.42 9.5 8.8 0.41 9.5 1.3 3.1 2 1 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 EGE03793.1 - 0.43 10.2 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KH_1 PF00013.29 EGE03794.1 - 1e-98 323.2 12.3 1.4e-12 47.2 0.3 13.8 13 2 0 13 13 13 9 KH domain SLS PF14611.6 EGE03794.1 - 1.8e-11 44.3 0.0 0.14 12.0 0.0 7.0 3 3 5 8 8 8 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EGE03794.1 - 5.8e-09 35.7 20.5 0.0033 17.2 0.2 8.2 8 1 0 8 8 8 3 KH domain KH_4 PF13083.6 EGE03794.1 - 0.00051 19.9 4.8 19 5.2 0.1 6.0 7 0 0 7 7 7 1 KH domain BMC PF00936.19 EGE03794.1 - 0.42 10.6 7.6 0.35 10.9 0.2 4.0 5 0 0 5 5 5 0 BMC domain KH_5 PF13184.6 EGE03794.1 - 0.65 10.1 9.2 38 4.5 0.3 5.8 6 0 0 6 6 6 0 NusA-like KH domain UCH_1 PF13423.6 EGE03795.1 - 4.3e-96 322.3 0.8 5.7e-96 321.9 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EGE03795.1 - 3.8e-14 53.6 0.0 3.8e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 EGE03795.1 - 0.0026 17.3 0.0 0.01 15.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3632 PF12311.8 EGE03796.1 - 4.1e-14 53.4 0.0 7.2e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3632) MSC PF09402.10 EGE03797.1 - 7.4e-105 351.1 0.0 1e-104 350.6 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EGE03797.1 - 2.9e-16 58.9 0.1 5.7e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.21 EGE03798.1 - 2e-51 175.1 0.0 3e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EGE03798.1 - 7.1e-41 137.8 63.9 1.3e-11 44.0 7.7 11.0 7 3 6 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 EGE03798.1 - 6.2e-37 125.0 67.1 2.4e-06 27.8 2.2 12.4 7 2 7 14 14 14 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EGE03798.1 - 3.8e-27 95.1 0.0 2.6e-26 92.4 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EGE03798.1 - 6.8e-09 35.5 16.3 0.0038 16.7 1.1 4.8 2 1 3 5 5 5 5 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 EGE03798.1 - 1.4e-08 34.3 0.1 6.3e-08 32.2 0.1 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EGE03798.1 - 4.7e-08 32.5 60.9 2.1 9.2 0.1 15.9 16 2 0 16 16 16 5 Leucine Rich Repeat LRR_5 PF13306.6 EGE03798.1 - 8.6e-06 25.7 5.0 0.057 13.4 0.2 4.0 3 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EGE03798.1 - 0.00042 20.1 48.2 4.2 7.7 0.3 13.4 15 0 0 15 15 15 4 Leucine Rich repeat RA PF00788.23 EGE03798.1 - 0.058 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain tRNA-synt_1b PF00579.25 EGE03799.1 - 2.6e-66 223.9 0.0 3.2e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Pkinase PF00069.25 EGE03802.1 - 2.5e-07 30.4 0.0 3.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03802.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 EGE03802.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.6 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_16 PF00722.21 EGE03803.1 - 1.9e-43 148.0 0.1 1.9e-43 148.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 EGE03803.1 - 0.0033 17.6 0.2 0.0033 17.6 0.2 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily MFS_1 PF07690.16 EGE03804.1 - 1.1e-35 123.2 25.7 1.1e-35 123.2 25.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily S4 PF01479.25 EGE03806.1 - 2e-11 43.4 0.0 3.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EGE03806.1 - 2e-10 41.4 2.8 3e-10 40.9 2.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain PilP PF04351.13 EGE03806.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 Pilus assembly protein, PilP ADH_zinc_N PF00107.26 EGE03807.1 - 6.8e-08 32.5 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lsm_interact PF05391.11 EGE03809.1 - 0.00033 20.0 5.2 0.24 10.9 0.5 2.5 2 0 0 2 2 2 2 Lsm interaction motif Ykof PF07615.11 EGE03809.1 - 0.018 15.5 1.2 1.7 9.1 0.0 2.8 3 1 0 3 3 3 0 YKOF-related Family Inhibitor_I53 PF11714.8 EGE03809.1 - 0.02 15.1 0.0 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Spore_YpjB PF09577.10 EGE03809.1 - 0.17 11.7 0.4 0.26 11.1 0.4 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) baeRF_family12 PF18856.1 EGE03810.1 - 0.055 14.1 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 DnaJ PF00226.31 EGE03811.1 - 1.8e-23 82.4 2.4 2.9e-23 81.7 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EGE03811.1 - 5e-23 81.8 0.0 7.2e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGE03811.1 - 1.8e-13 50.7 16.8 2.8e-13 50.0 16.8 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGE03811.1 - 0.00053 19.9 8.3 0.12 12.3 1.7 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGE03811.1 - 0.067 13.2 6.9 2.2 8.3 1.1 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4449 PF14613.6 EGE03812.1 - 1e-05 25.7 5.2 0.00011 22.3 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Ku_PK_bind PF08785.11 EGE03812.1 - 0.0067 16.6 0.3 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 Ku C terminal domain like Maelstrom PF13017.6 EGE03812.1 - 0.057 13.1 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Kinesin PF00225.23 EGE03813.1 - 1.4e-29 103.1 0.5 2.1e-29 102.5 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.16 EGE03813.1 - 0.073 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain malic PF00390.19 EGE03814.1 - 1.4e-64 217.3 0.0 2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EGE03814.1 - 1.3e-26 93.4 0.1 1.9e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain PTR2 PF00854.21 EGE03815.1 - 2.7e-57 194.4 1.1 7.3e-57 193.0 1.1 1.6 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 EGE03815.1 - 0.014 14.4 13.5 0.0046 15.9 6.3 2.7 1 1 2 3 3 3 0 Major Facilitator Superfamily THOC7 PF05615.13 EGE03816.1 - 1.5e-44 151.5 8.9 1.5e-44 151.5 8.9 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC92 PF14916.6 EGE03816.1 - 0.0025 17.5 0.2 0.0071 16.1 0.2 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function DUF1843 PF08898.10 EGE03816.1 - 0.031 14.8 2.2 0.032 14.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Peroxin-13_N PF04088.13 EGE03816.1 - 0.069 13.4 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region LMBR1 PF04791.16 EGE03816.1 - 4.4 6.1 7.8 5.6 5.8 7.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 EGE03816.1 - 7.2 5.0 10.6 8.6 4.8 9.7 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.16 EGE03817.1 - 8.5e-22 77.3 9.3 1.6e-21 76.4 8.9 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor A AdoMet_Synthase PF01941.19 EGE03817.1 - 0.028 13.2 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) FIVAR PF07554.13 EGE03817.1 - 0.033 14.9 1.1 0.033 14.9 1.1 2.0 2 0 0 2 2 2 0 FIVAR domain DUF948 PF06103.11 EGE03817.1 - 0.05 13.9 0.7 0.072 13.4 0.1 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.6 EGE03817.1 - 0.1 13.1 4.3 0.15 12.6 4.3 1.3 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.11 EGE03817.1 - 0.25 11.1 3.5 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Dynamin_M PF01031.20 EGE03817.1 - 0.28 10.4 4.5 0.21 10.8 0.2 2.0 2 0 0 2 2 2 0 Dynamin central region APG6_N PF17675.1 EGE03817.1 - 0.4 11.2 14.3 1.3 9.6 14.3 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EGE03817.1 - 2.4 8.2 14.5 1.4 8.9 2.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.9 EGE03817.1 - 4.6 8.0 7.6 5.3 7.8 2.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 EGE03817.1 - 9.7 6.5 8.9 2.2 8.6 1.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Band_7 PF01145.25 EGE03819.1 - 3.8e-16 59.6 0.0 3.8e-16 59.6 0.0 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Sugar_tr PF00083.24 EGE03820.1 - 1.1e-84 284.9 23.0 1.3e-84 284.7 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE03820.1 - 1.8e-15 56.8 34.4 3.4e-12 46.0 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 EGE03820.1 - 1.1 8.7 11.5 0.38 10.2 4.3 2.5 2 1 0 2 2 2 0 Emopamil binding protein HERV-K_REC PF15695.5 EGE03821.1 - 0.06 13.4 3.2 0.08 13.0 0.3 2.4 2 1 1 3 3 3 0 Rec (regulator of expression encoded by corf) of HERV-K-113 DUF4611 PF15387.6 EGE03821.1 - 0.063 13.5 3.2 0.098 12.9 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) F-box-like PF12937.7 EGE03822.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EGE03822.1 - 0.02 14.8 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain Stc1 PF12898.7 EGE03822.1 - 0.038 14.5 2.0 0.14 12.8 0.5 2.3 2 0 0 2 2 2 0 Stc1 domain zf-C2HCIx2C PF10782.9 EGE03822.1 - 3 7.8 5.9 1.2 9.1 3.1 1.8 2 0 0 2 2 2 0 Zinc-finger Elongin_A PF06881.11 EGE03823.1 - 3.2e-28 98.3 1.6 5.7e-28 97.5 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sfi1 PF08457.10 EGE03824.1 - 2.2e-197 657.1 89.4 3.7e-196 653.1 78.9 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein IZUMO PF15005.6 EGE03824.1 - 0.07 13.7 1.2 0.45 11.0 1.2 2.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Alpha_kinase PF02816.18 EGE03824.1 - 7.8 6.6 6.3 0.74 9.9 0.1 2.5 3 0 0 3 3 3 0 Alpha-kinase family p450 PF00067.22 EGE03825.1 - 4.9e-74 249.7 0.0 7.5e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EGE03825.1 - 1.9e-27 96.3 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGE03825.1 - 1.2e-21 77.4 0.0 2.8e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGE03825.1 - 2.2e-11 44.3 0.0 4.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGE03825.1 - 0.00096 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain tRNA-synt_1 PF00133.22 EGE03826.1 - 3.6e-223 742.2 0.0 5e-223 741.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGE03826.1 - 6.8e-24 84.6 0.0 2.1e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGE03826.1 - 2.3e-13 49.7 0.0 9.9e-06 24.5 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGE03826.1 - 0.078 12.3 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 EGE03827.1 - 4.7e-111 370.9 0.2 5.4e-110 367.4 0.0 2.6 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EGE03827.1 - 5.1e-17 62.4 41.3 5.1e-17 62.4 41.3 3.5 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2570 PF10828.8 EGE03827.1 - 0.56 10.0 29.1 0.16 11.8 7.7 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2570) Filament PF00038.21 EGE03827.1 - 1.3 8.5 50.8 2.7 7.5 50.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein UPF0227 PF05728.12 EGE03827.1 - 9.2 6.2 8.7 7.2 6.5 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) XRN_M PF17846.1 EGE03828.1 - 8.4e-154 512.8 0.1 8.4e-154 512.8 0.1 1.8 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EGE03828.1 - 6.7e-99 330.2 2.4 3e-98 328.1 0.0 2.6 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus EPSP_synthase PF00275.20 EGE03829.1 - 2.7e-131 438.1 0.0 5e-131 437.2 0.0 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EGE03829.1 - 6.4e-98 327.1 0.0 1.1e-97 326.3 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EGE03829.1 - 2e-56 191.8 0.0 4.8e-56 190.6 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EGE03829.1 - 4e-36 124.5 0.0 8.7e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 EGE03829.1 - 7.1e-26 90.3 0.0 2.1e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EGE03829.1 - 2.2e-07 30.5 0.9 6.5e-07 29.0 0.2 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EGE03829.1 - 4.9e-07 29.7 0.0 1.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EGE03829.1 - 3.8e-05 23.8 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_24 PF13479.6 EGE03829.1 - 0.00087 19.1 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE03829.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGE03829.1 - 0.12 12.9 0.1 0.31 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 EGE03830.1 - 6.4e-25 87.1 0.0 4.5e-17 62.0 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EGE03830.1 - 8.6e-10 38.6 0.0 0.00011 22.1 0.0 2.8 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGE03830.1 - 5.7e-07 29.1 0.0 0.23 11.2 0.0 3.8 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 EGE03830.1 - 1.3e-05 25.2 5.3 7.2e-05 22.8 0.0 4.1 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 EGE03830.1 - 0.014 14.8 0.0 0.054 12.9 0.0 1.9 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Cas_Cmr3 PF09700.10 EGE03830.1 - 0.064 12.7 1.4 0.2 11.0 0.7 1.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) DEAD PF00270.29 EGE03831.1 - 2.8e-50 170.5 0.0 6.2e-49 166.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE03831.1 - 1.3e-29 102.7 0.0 3.8e-29 101.3 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03831.1 - 9.5e-05 22.5 0.0 0.00032 20.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGE03831.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.6 EGE03831.1 - 0.021 15.1 0.0 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 EGE03831.1 - 0.04 13.3 0.7 1.9 7.8 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF5335 PF17269.2 EGE03831.1 - 0.051 13.4 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) AAA_22 PF13401.6 EGE03831.1 - 0.37 11.1 1.9 20 5.5 0.0 3.2 3 1 1 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 EGE03832.1 - 2.8e-82 275.8 1.8 3.7e-82 275.4 1.8 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EGE03832.1 - 1.1e-52 178.9 0.3 1.8e-52 178.2 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EGE03832.1 - 1.4e-08 34.4 0.1 1.4e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EGE03832.1 - 0.00022 20.7 0.5 0.014 14.8 0.1 2.5 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Paramyxo_C PF01692.18 EGE03833.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C zf-C2H2 PF00096.26 EGE03833.1 - 0.31 11.6 1.4 0.4 11.2 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sds3 PF08598.11 EGE03841.1 - 4.9e-47 160.7 8.2 4.4e-46 157.6 2.4 2.2 1 1 1 2 2 2 2 Sds3-like Collagen PF01391.18 EGE03843.1 - 4e-23 80.9 164.1 5.7e-10 38.8 45.6 6.2 4 2 2 6 6 6 3 Collagen triple helix repeat (20 copies) CFEM PF05730.11 EGE03843.1 - 1.1e-05 25.4 0.9 1.1e-05 25.4 0.9 2.7 2 0 0 2 2 2 1 CFEM domain HDC PF02329.16 EGE03848.1 - 0.092 11.8 0.0 0.097 11.7 0.0 1.0 1 0 0 1 1 1 0 Histidine carboxylase PI chain PilO PF04350.13 EGE03849.1 - 0.016 15.4 1.1 0.039 14.1 0.3 2.0 1 1 1 2 2 2 0 Pilus assembly protein, PilO Baculo_PEP_C PF04513.12 EGE03849.1 - 0.019 15.0 0.7 0.019 15.0 0.7 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med3 PF11593.8 EGE03849.1 - 0.16 11.1 15.9 0.13 11.4 8.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2752 PF10825.8 EGE03849.1 - 0.29 11.2 1.1 0.49 10.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF148 PF02520.17 EGE03849.1 - 2.4 8.3 6.6 0.17 12.0 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 RCC1 PF00415.18 EGE03850.1 - 7.3e-48 161.0 10.0 4.6e-11 43.2 0.0 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGE03850.1 - 6.4e-36 121.4 28.6 1.7e-07 30.8 1.4 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat p450 PF00067.22 EGE03851.1 - 7.6e-28 97.5 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sterol_MT_C PF08498.10 EGE03852.1 - 1.9e-23 82.6 0.1 3.4e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGE03852.1 - 9.8e-20 71.0 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE03852.1 - 1.3e-18 67.2 0.0 1.8e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE03852.1 - 2.2e-18 66.7 0.0 4.2e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE03852.1 - 1.1e-13 51.1 0.0 1.8e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGE03852.1 - 5.4e-13 48.9 0.0 7.3e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGE03852.1 - 6.3e-13 48.9 0.0 9.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE03852.1 - 4.4e-10 40.2 0.0 9.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGE03852.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGE03852.1 - 0.0027 17.2 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGE03852.1 - 0.0052 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGE03852.1 - 0.0096 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EGE03852.1 - 0.065 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DRE2_N PF16803.5 EGE03852.1 - 0.088 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Methyltransf_32 PF13679.6 EGE03852.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGE03852.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase BTB PF00651.31 EGE03853.1 - 3e-06 27.4 0.0 8.6e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Peptidase_S24 PF00717.23 EGE03854.1 - 5.7e-08 32.6 0.0 8.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 EGE03857.1 - 2.3e-40 137.5 0.0 2.8e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE03857.1 - 2.2e-06 27.4 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGE03857.1 - 0.037 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EGE03857.1 - 0.082 13.2 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain Acyl_transf_3 PF01757.22 EGE03858.1 - 2.9e-08 33.1 29.5 6.8e-08 31.9 28.8 1.9 1 1 1 2 2 2 1 Acyltransferase family RabGAP-TBC PF00566.18 EGE03861.1 - 1.8e-34 119.3 0.4 4.2e-31 108.3 0.1 3.0 3 1 0 3 3 3 2 Rab-GTPase-TBC domain PIG-S PF10510.9 EGE03862.1 - 0.0091 14.9 1.7 0.28 9.9 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein BCS1_N PF08740.11 EGE03863.1 - 1e-48 165.8 0.6 1.5e-48 165.3 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGE03863.1 - 2e-18 67.1 0.0 4e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE03863.1 - 8.1e-06 26.3 0.0 2.1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGE03863.1 - 0.00066 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGE03863.1 - 0.0063 16.7 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGE03863.1 - 0.012 15.9 0.0 0.086 13.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EGE03863.1 - 0.013 15.0 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGE03863.1 - 0.015 15.0 0.0 0.06 13.1 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGE03863.1 - 0.016 15.2 0.0 0.047 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGE03863.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGE03863.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase ABC_tran PF00005.27 EGE03863.1 - 0.041 14.4 0.0 0.082 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGE03863.1 - 0.046 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE03863.1 - 0.13 12.1 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 EGE03863.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 EGE03863.1 - 0.14 11.9 0.0 0.73 9.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain Rad17 PF03215.15 EGE03863.1 - 0.2 11.6 0.0 0.58 10.1 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain Lactamase_B_2 PF12706.7 EGE03864.1 - 2.5e-09 36.9 0.0 1.8e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGE03864.1 - 9.8e-05 22.3 0.0 0.00031 20.7 0.0 1.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Cpn60_TCP1 PF00118.24 EGE03866.1 - 3.6e-172 573.4 1.5 4.1e-172 573.2 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 EGE03867.1 - 4e-40 136.8 14.2 6.3e-40 136.1 14.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EGE03867.1 - 0.0048 16.1 0.0 0.0069 15.6 0.0 1.1 1 0 0 1 1 1 1 Lyase, catalytic PPL5 PF18168.1 EGE03867.1 - 0.09 12.1 3.7 0.12 11.7 3.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 EGE03867.1 - 0.16 12.0 7.5 0.25 11.4 7.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ERK-JNK_inhib PF15002.6 EGE03867.1 - 1.6 8.3 13.8 2.5 7.7 13.8 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Vfa1 PF08432.10 EGE03867.1 - 3.8 7.8 15.3 6.4 7.1 15.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 EGE03867.1 - 7.3 5.2 5.2 6.9 5.3 5.2 1.1 1 0 0 1 1 1 0 Presenilin FAD_binding_4 PF01565.23 EGE03870.1 - 1.9e-18 66.5 0.3 3.7e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE03870.1 - 2.4e-10 40.4 0.2 5.6e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.25 EGE03872.1 - 5.5e-62 209.2 0.0 9.2e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGE03872.1 - 3.3e-21 75.6 3.1 9.9e-21 74.0 2.6 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EGE03872.1 - 0.0092 16.4 0.0 0.59 10.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGE03872.1 - 0.011 15.6 0.6 0.031 14.2 0.0 2.0 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 EGE03872.1 - 0.019 14.2 0.3 0.097 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EGE03872.1 - 0.026 14.4 0.0 0.079 12.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGE03872.1 - 0.035 14.5 1.0 0.48 10.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGE03872.1 - 0.039 13.9 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EGE03872.1 - 0.046 13.1 0.2 0.085 12.2 0.2 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 EGE03872.1 - 0.057 13.3 0.8 0.28 11.1 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RNA_helicase PF00910.22 EGE03872.1 - 0.079 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGE03872.1 - 0.097 13.0 0.1 0.36 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Alpha-amylase_C PF02806.18 EGE03873.1 - 4.5e-26 91.2 0.0 1.1e-25 89.9 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EGE03873.1 - 8.3e-19 67.7 0.0 2.6e-18 66.1 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EGE03873.1 - 5e-16 59.2 0.0 3.6e-11 43.2 0.2 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain COX4 PF02936.14 EGE03874.1 - 1.3e-45 154.8 0.3 1.8e-45 154.3 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EGE03874.1 - 0.017 15.6 2.7 0.017 15.6 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1138 PF06592.13 EGE03874.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) DUF1104 PF06518.11 EGE03874.1 - 0.14 12.5 0.3 0.14 12.5 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1104) Cofilin_ADF PF00241.20 EGE03875.1 - 6.6e-34 116.3 0.0 7.5e-34 116.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 EGE03876.1 - 4.9e-86 289.3 10.5 7.3e-86 288.7 10.5 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CHASE6_C PF17150.4 EGE03876.1 - 0.18 12.5 0.0 21 5.9 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain Myb_DNA-binding PF00249.31 EGE03877.1 - 0.02 15.1 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EGE03877.1 - 0.036 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ATP-synt_Eps PF04627.13 EGE03878.1 - 2.7e-21 75.3 0.3 3.5e-21 74.9 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 EGE03879.1 - 8.4e-63 210.9 0.0 1.7e-62 209.8 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ORC5_C PF14630.6 EGE03880.1 - 1e-77 261.5 0.0 1.4e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EGE03880.1 - 5.1e-20 72.5 0.0 1e-19 71.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EGE03880.1 - 1.3e-06 28.5 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 EGE03880.1 - 0.00076 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGE03880.1 - 0.0017 18.7 0.0 0.0041 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGE03880.1 - 0.0055 16.0 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain ABC_tran PF00005.27 EGE03880.1 - 0.009 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 EGE03880.1 - 0.01 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGE03880.1 - 0.011 16.3 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGE03880.1 - 0.011 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGE03880.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EGE03880.1 - 0.018 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGE03880.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGE03880.1 - 0.069 12.7 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_27 PF13514.6 EGE03880.1 - 0.088 12.4 0.2 7.6 6.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 EGE03880.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGE03880.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 EGE03880.1 - 0.13 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EGE03880.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.19 EGE03880.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ATPase_2 PF01637.18 EGE03880.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGE03880.1 - 0.21 12.0 0.1 0.53 10.7 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.21 EGE03880.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase ATP_bind_1 PF03029.17 EGE03880.1 - 0.25 11.1 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EGE03880.1 - 0.28 10.4 0.0 0.59 9.4 0.0 1.6 2 0 0 2 2 1 0 Septin PUF PF00806.19 EGE03881.1 - 9.1e-57 185.7 8.4 1.3e-07 30.9 0.0 9.0 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat LolA_2 PF16584.5 EGE03881.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA RNA_pol_Rpb2_6 PF00562.28 EGE03883.1 - 4.6e-124 414.4 0.0 7.8e-124 413.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGE03883.1 - 6.5e-56 189.1 0.4 9.7e-56 188.5 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGE03883.1 - 5.5e-31 106.8 0.4 1.3e-30 105.6 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGE03883.1 - 8.7e-30 103.8 1.9 3.7e-29 101.7 1.6 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGE03883.1 - 4.4e-26 90.9 0.6 1.3e-25 89.4 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGE03883.1 - 3.2e-18 65.7 0.0 7.7e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EGE03883.1 - 1.9e-11 44.4 0.5 7e-11 42.5 0.5 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L22e PF01776.17 EGE03883.1 - 0.18 12.2 0.9 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L22e protein family DUF3632 PF12311.8 EGE03884.1 - 2.4e-44 151.8 10.5 3.1e-44 151.5 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glycos_transf_1 PF00534.20 EGE03887.1 - 1.9e-20 73.1 0.0 3.7e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGE03887.1 - 6.3e-13 49.3 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGE03887.1 - 0.00027 21.3 0.0 0.00086 19.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.20 EGE03888.1 - 6e-48 162.8 5.0 6e-48 162.8 5.0 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGE03888.1 - 1.9e-17 64.2 0.0 5.1e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE03888.1 - 2.2e-11 43.2 0.0 5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGE03888.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGE03888.1 - 0.0037 17.1 1.6 0.005 16.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 EGE03888.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) O-antigen_lig PF13425.6 EGE03888.1 - 0.12 11.1 5.6 0.33 9.7 5.6 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein APC_u13 PF16634.5 EGE03890.1 - 0.15 12.0 3.5 0.28 11.1 0.2 2.2 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr and SAMP YqzE PF14038.6 EGE03890.1 - 0.63 10.1 2.1 0.7 9.9 0.0 2.0 2 1 0 2 2 2 0 YqzE-like protein Connexin PF00029.19 EGE03891.1 - 0.0034 17.2 0.7 0.0036 17.1 0.7 1.1 1 0 0 1 1 1 1 Connexin FAM176 PF14851.6 EGE03891.1 - 0.0044 16.7 2.9 0.0051 16.5 2.9 1.1 1 0 0 1 1 1 1 FAM176 family RNA_pol_Rpc4 PF05132.14 EGE03891.1 - 0.011 16.1 1.0 0.013 16.0 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 ORC6 PF05460.13 EGE03891.1 - 0.013 14.8 3.3 0.014 14.7 3.3 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AP3D1 PF06375.11 EGE03891.1 - 0.039 14.2 10.0 0.047 13.9 10.0 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF3405 PF11885.8 EGE03891.1 - 0.041 12.5 2.9 0.049 12.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) CLN3 PF02487.17 EGE03891.1 - 0.041 12.9 0.2 0.043 12.9 0.2 1.0 1 0 0 1 1 1 0 CLN3 protein Folate_carrier PF01770.18 EGE03891.1 - 0.048 12.4 0.8 0.055 12.2 0.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_polI_A34 PF08208.11 EGE03891.1 - 0.05 13.7 13.3 0.055 13.6 13.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RPN2_C PF18004.1 EGE03891.1 - 0.053 13.5 7.3 0.06 13.3 7.3 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CSG2 PF16965.5 EGE03891.1 - 0.056 12.4 0.1 0.059 12.3 0.1 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator V_ATPase_I PF01496.19 EGE03891.1 - 0.056 11.4 0.6 0.069 11.1 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnd2 PF05786.14 EGE03891.1 - 0.065 11.9 8.3 0.074 11.7 8.3 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Ferlin_C PF16165.5 EGE03891.1 - 0.074 13.0 6.1 0.085 12.8 6.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus OATP PF03137.20 EGE03891.1 - 0.078 11.3 1.5 0.089 11.1 1.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.14 EGE03891.1 - 0.13 12.0 2.5 0.16 11.7 2.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4710 PF15828.5 EGE03891.1 - 0.18 12.0 11.3 0.24 11.5 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) CDC45 PF02724.14 EGE03891.1 - 0.23 9.7 6.8 0.22 9.8 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein XRN_N PF03159.18 EGE03891.1 - 0.23 10.9 4.6 0.25 10.7 4.6 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Presenilin PF01080.17 EGE03891.1 - 0.35 9.6 2.4 0.36 9.5 2.4 1.1 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 EGE03891.1 - 0.37 8.8 2.4 0.43 8.6 2.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2828 PF11443.8 EGE03891.1 - 0.39 8.8 6.1 0.42 8.6 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MCM_bind PF09739.9 EGE03891.1 - 0.67 8.3 5.2 0.72 8.2 5.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TMEM208_SND2 PF05620.11 EGE03891.1 - 0.72 9.6 3.8 0.91 9.3 3.8 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Pap_E4 PF02711.14 EGE03891.1 - 0.9 10.5 5.8 1.3 10.1 5.8 1.2 1 0 0 1 1 1 0 E4 protein DUF3899 PF13038.6 EGE03891.1 - 1.2 9.7 4.2 1.9 9.1 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF3682 PF12446.8 EGE03891.1 - 2.6 8.5 7.8 3.6 8.1 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peptidase_S49_N PF08496.10 EGE03891.1 - 3 7.9 8.0 3.6 7.6 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3464 PF11947.8 EGE03891.1 - 3.1 7.5 7.1 3.6 7.3 7.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RuvC_III PF18541.1 EGE03891.1 - 4.1 7.3 0.0 4.1 7.3 0.0 2.0 1 1 1 2 2 2 0 RuvC endonuclease subdomain 3 MAS20 PF02064.15 EGE03891.1 - 6.2 6.9 9.3 7.6 6.6 9.3 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor Med19 PF10278.9 EGE03891.1 - 7.6 6.4 15.3 9.8 6.1 15.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleo_P87 PF07267.11 EGE03891.1 - 8.3 5.1 9.8 9.8 4.9 9.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CTD_bind PF04818.13 EGE03892.1 - 1.4e-08 35.4 0.0 2.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EGE03892.1 - 3e-07 30.2 0.0 5.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 EGE03892.1 - 6.3 6.7 20.3 9.6 6.1 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DSPc PF00782.20 EGE03894.1 - 8.8e-20 70.9 0.0 4.7e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE03894.1 - 0.0062 16.1 1.1 0.012 15.1 0.3 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase HeLo PF14479.6 EGE03894.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation Citrate_synt PF00285.21 EGE03895.1 - 2.6e-100 336.0 0.0 3.4e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EGE03895.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 EGE03897.1 - 1.7e-25 88.8 6.4 8.8e-12 44.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.20 EGE03898.1 - 3.9e-17 62.6 0.0 7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGE03898.1 - 3.7e-12 46.6 0.0 6.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 EGE03899.1 - 2.5e-39 135.6 0.0 4e-35 121.8 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EGE03899.1 - 5.5e-22 77.6 3.1 5.5e-15 55.2 0.2 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EGE03899.1 - 3.3e-08 33.3 0.0 4.5e-06 26.5 0.1 2.8 2 1 0 2 2 2 1 TFIIE alpha subunit CENP-B_dimeris PF09026.10 EGE03899.1 - 0.019 15.4 3.6 0.29 11.6 0.4 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EGE03899.1 - 0.17 11.5 6.8 1.6 8.4 0.5 3.4 3 0 0 3 3 3 0 FAM176 family PBP1_TM PF14812.6 EGE03899.1 - 6.1 7.3 9.6 8.1 6.9 1.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec8_exocyst PF04048.14 EGE03900.1 - 1.8e-39 134.8 0.6 1.8e-39 134.8 0.6 2.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EGE03900.1 - 2.2e-06 27.2 1.1 4.9e-06 26.0 1.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex bZIP_Maf PF03131.17 EGE03900.1 - 0.091 13.3 0.5 0.29 11.7 0.5 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor HIP1_clath_bdg PF16515.5 EGE03900.1 - 2.5 8.8 5.5 27 5.5 0.7 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Zn_clus PF00172.18 EGE03902.1 - 2e-08 34.2 13.5 2.7e-08 33.8 13.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD20L1_u1 PF16660.5 EGE03902.1 - 0.042 14.6 1.1 0.063 14.0 1.1 1.3 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 Tannase PF07519.11 EGE03903.1 - 2.3e-97 326.9 0.0 2.6e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EGE03903.1 - 0.00021 20.8 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGE03903.1 - 0.0094 15.2 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 EGE03905.1 - 2.5e-12 46.6 0.0 3.2e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Rit1_C PF17184.4 EGE03906.1 - 1.7e-97 326.2 0.0 2.1e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGE03906.1 - 6.9e-17 61.7 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 EGE03908.1 - 3.7e-19 69.5 0.0 4.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 EGE03908.1 - 8.9e-07 28.8 0.0 2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EGE03908.1 - 2.4e-05 24.7 0.1 0.00016 22.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE03908.1 - 0.0016 18.4 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4853 PF16145.5 EGE03908.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4853) NUDIX PF00293.28 EGE03909.1 - 8.1e-16 58.3 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TetR_C_30 PF17939.1 EGE03909.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NUDIX PF00293.28 EGE03910.1 - 5.8e-09 36.1 0.0 9.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.6 EGE03913.1 - 4e-11 42.6 6.7 7.4e-11 41.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGE03913.1 - 2.5e-05 24.0 5.1 6.1e-05 22.8 5.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGE03913.1 - 7.4e-05 22.5 4.5 0.00014 21.7 3.7 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE03913.1 - 0.00065 20.0 7.9 0.0012 19.1 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGE03913.1 - 0.0022 17.9 5.1 0.0037 17.2 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGE03913.1 - 0.0095 15.8 4.2 0.0095 15.8 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 EGE03913.1 - 0.48 8.7 6.0 0.66 8.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EGE03913.1 - 1.3 7.7 6.1 1.8 7.2 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-C3HC4_4 PF15227.6 EGE03913.1 - 1.9 8.7 4.7 7.1 6.9 4.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING EST1_DNA_bind PF10373.9 EGE03914.1 - 7.3e-10 38.8 1.3 7.3e-10 38.8 1.3 3.1 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain 5_nucleotid PF05761.14 EGE03914.1 - 0.022 13.7 0.8 0.037 12.9 0.8 1.3 1 0 0 1 1 1 0 5' nucleotidase family TFIIB PF00382.19 EGE03915.1 - 0.00053 20.0 0.0 0.035 14.1 0.0 2.5 2 1 0 2 2 2 2 Transcription factor TFIIB repeat Autophagy_N PF03986.13 EGE03916.1 - 5.5e-45 152.7 1.9 6.4e-45 152.5 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EGE03916.1 - 1.4e-15 56.4 0.5 2.3e-15 55.8 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EGE03916.1 - 3.5e-14 53.1 0.1 5.7e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Kdo PF06293.14 EGE03917.1 - 0.0009 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE03917.1 - 0.0052 16.7 0.2 0.0052 16.7 0.2 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE03917.1 - 0.065 12.8 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fez1 PF06818.15 EGE03918.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Fez1 Dicty_CAR PF05462.11 EGE03919.1 - 1.4e-11 44.1 7.7 1.4e-11 44.1 7.7 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGE03919.1 - 2.6e-06 26.9 11.2 2.5e-05 23.7 10.4 2.3 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EGE03919.1 - 2e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EGE03919.1 - 0.00024 20.9 6.9 0.00024 20.9 6.9 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 EGE03919.1 - 0.00037 19.6 12.5 0.13 11.3 12.5 2.3 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7TM_GPCR_Srsx PF10320.9 EGE03919.1 - 0.0031 16.9 2.1 0.0052 16.2 2.1 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx SUIM_assoc PF16619.5 EGE03919.1 - 0.06 13.4 4.8 0.15 12.2 4.8 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GPR_Gpa2_C PF11970.8 EGE03919.1 - 0.15 12.1 2.1 0.31 11.2 0.4 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2304 PF10066.9 EGE03919.1 - 9.8 6.5 9.4 1.3 9.3 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Glycos_transf_2 PF00535.26 EGE03920.1 - 3.6e-23 82.2 0.0 4e-21 75.6 0.0 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGE03920.1 - 0.0001 22.3 0.0 0.36 10.7 0.0 3.0 2 1 1 3 3 3 2 Glycosyltransferase like family 2 HOOK PF05622.12 EGE03921.1 - 0.064 11.4 10.4 4.9 5.2 9.2 2.2 2 0 0 2 2 2 0 HOOK protein Spc7 PF08317.11 EGE03921.1 - 0.12 11.3 11.7 0.065 12.1 8.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein SKA1 PF07160.12 EGE03921.1 - 0.14 12.0 5.7 0.037 13.9 2.4 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Pox_A_type_inc PF04508.12 EGE03921.1 - 0.21 11.5 4.7 2.1 8.3 1.0 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FPP PF05911.11 EGE03921.1 - 0.28 9.3 12.5 2 6.5 8.9 2.1 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil FapA PF03961.13 EGE03921.1 - 0.34 9.5 4.3 0.64 8.6 4.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cauli_AT PF03233.13 EGE03921.1 - 0.4 10.6 5.8 0.4 10.6 2.3 2.2 2 0 0 2 2 2 0 Aphid transmission protein Filament PF00038.21 EGE03921.1 - 0.52 9.9 12.6 0.073 12.6 8.4 1.7 2 0 0 2 2 2 0 Intermediate filament protein Golgin_A5 PF09787.9 EGE03921.1 - 0.61 9.5 9.7 1.3 8.4 9.7 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2570 PF10828.8 EGE03921.1 - 0.66 9.8 9.6 1.1 9.1 8.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PRKG1_interact PF15898.5 EGE03921.1 - 0.73 10.8 16.2 59 4.6 0.1 3.7 3 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain ALMT PF11744.8 EGE03921.1 - 1.5 7.6 4.5 2.5 6.8 4.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-Q PF13094.6 EGE03921.1 - 1.6 8.9 15.8 27 4.9 15.8 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.15 EGE03921.1 - 4.5 6.8 10.0 0.55 9.7 5.0 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EGE03921.1 - 5.4 4.8 6.2 8.2 4.2 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 EGE03921.1 - 6.4 5.9 6.2 11 5.1 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Swi5 PF07061.11 EGE03922.1 - 2.2e-28 98.1 0.3 2.9e-28 97.7 0.3 1.2 1 0 0 1 1 1 1 Swi5 DUF641 PF04859.12 EGE03922.1 - 0.077 13.3 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 EGE03922.1 - 0.12 12.6 2.6 0.21 11.9 2.6 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ytp1 PF10355.9 EGE03923.1 - 3.7e-71 239.6 19.6 3.7e-71 239.6 19.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGE03923.1 - 6.3e-32 109.5 3.3 6.3e-32 109.5 3.3 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) ExoD PF06055.12 EGE03923.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.9 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD DUF3180 PF11377.8 EGE03923.1 - 0.16 12.1 9.0 1.9 8.6 5.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) DUF973 PF06157.11 EGE03923.1 - 0.33 10.0 9.7 0.27 10.3 7.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF973) ThiF PF00899.21 EGE03924.1 - 2e-32 112.5 0.0 2.5e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family zf-C4H2 PF10146.9 EGE03925.1 - 0.037 14.3 5.5 0.089 13.1 5.5 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein PRIMA1 PF16101.5 EGE03925.1 - 0.82 9.7 6.5 0.25 11.4 2.9 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EGE03925.1 - 8.9 5.7 10.2 1.4 8.4 6.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 EGE03926.1 - 6.7e-38 130.5 28.8 6.7e-38 130.5 28.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3464 PF11947.8 EGE03926.1 - 0.28 10.9 0.6 1.5 8.5 0.0 2.3 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 Acyl_transf_3 PF01757.22 EGE03926.1 - 1.9 7.4 36.4 2.1 7.3 16.3 3.1 2 1 1 3 3 3 0 Acyltransferase family Na_H_Exchanger PF00999.21 EGE03927.1 - 3.1e-59 200.7 44.8 4.6e-59 200.1 44.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UDPG_MGDP_dh_N PF03721.14 EGE03927.1 - 0.093 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peroxin-3 PF04882.12 EGE03928.1 - 1.4e-166 555.2 0.1 1.7e-166 554.9 0.1 1.1 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 EGE03929.1 - 3.4e-45 153.8 0.0 4e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 TB2_DP1_HVA22 PF03134.19 EGE03930.1 - 7.9e-22 77.0 8.7 7.9e-22 77.0 8.7 1.5 2 0 0 2 2 2 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 EGE03931.1 - 6.1e-27 94.1 0.1 1.5e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.12 EGE03932.1 - 4.7e-69 232.5 0.1 7.3e-69 231.9 0.1 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ_C PF01556.18 EGE03933.1 - 4.7e-36 124.1 0.5 6.2e-36 123.7 0.5 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGE03933.1 - 2.7e-28 97.9 1.7 4.8e-28 97.1 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain MMR_HSR1_Xtn PF16897.5 EGE03934.1 - 1.5e-34 118.2 1.3 8.9e-34 115.7 0.4 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGE03934.1 - 1.8e-20 73.1 0.0 4.5e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGE03934.1 - 8.6e-18 64.1 0.4 1.9e-17 63.1 0.1 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 EGE03934.1 - 1.3e-12 47.6 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGE03934.1 - 3.5e-05 23.9 0.3 0.04 14.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EGE03934.1 - 0.046 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 EGE03934.1 - 0.082 11.9 0.1 0.17 10.8 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGE03934.1 - 0.1 12.8 0.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EGE03934.1 - 0.12 11.5 0.1 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain Torus PF16131.5 EGE03935.1 - 4.6e-45 152.8 2.8 4.6e-45 152.8 0.0 2.4 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 EGE03935.1 - 2.2e-08 33.8 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGE03935.1 - 0.00026 20.9 1.0 0.00047 20.1 1.0 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EGE03935.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EGE03935.1 - 0.026 14.4 1.7 0.048 13.6 1.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ifi-6-16 PF06140.13 EGE03935.1 - 0.033 14.1 2.0 0.056 13.4 2.0 1.3 1 0 0 1 1 1 0 Interferon-induced 6-16 family zf-CCCH_4 PF18044.1 EGE03935.1 - 1.2 9.1 3.8 1.9 8.4 3.8 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger HGTP_anticodon2 PF12745.7 EGE03936.1 - 3.1e-85 285.9 3.0 7e-85 284.7 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EGE03936.1 - 5.3e-66 222.7 0.0 1e-36 126.6 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03936.1 - 2.7e-32 112.1 0.0 1.7e-18 66.9 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGE03936.1 - 5.3e-18 65.4 3.2 5.6e-18 65.3 0.9 2.3 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EGE03936.1 - 1.2e-11 44.5 1.2 6.8e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 EGE03936.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family gpUL132 PF11359.8 EGE03936.1 - 0.063 12.8 0.1 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 Glycoprotein UL132 Pkinase_fungal PF17667.1 EGE03936.1 - 0.78 8.4 3.0 0.52 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 EGE03936.1 - 2.4 8.1 8.1 4.5 7.2 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cut12 PF11500.8 EGE03937.1 - 2.7e-47 160.3 14.2 2.7e-47 160.3 14.2 4.1 3 1 1 4 4 4 1 Spindle pole body formation-associated protein DUF2730 PF10805.8 EGE03937.1 - 0.97 9.6 6.9 0.45 10.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF89 PF01937.19 EGE03938.1 - 1e-135 452.3 0.2 1.2e-135 452.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CENP-F_leu_zip PF10473.9 EGE03938.1 - 0.026 14.6 0.3 0.026 14.6 0.3 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 EGE03938.1 - 0.057 13.4 1.2 2.7 8.0 0.5 2.6 3 0 0 3 3 3 0 FlxA-like protein PPP5 PF08321.12 EGE03939.1 - 1.4e-34 118.2 0.3 3.3e-34 117.1 0.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EGE03939.1 - 1.9e-30 106.9 0.0 2.7e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EGE03939.1 - 1.4e-12 46.9 4.7 0.00012 21.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE03939.1 - 2.4e-11 43.1 5.0 4.3e-07 29.5 0.3 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.17 EGE03939.1 - 3.5e-10 39.2 4.4 0.0011 18.9 0.9 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE03939.1 - 1.5e-07 31.9 1.9 0.0057 17.3 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE03939.1 - 4.8e-06 26.6 0.1 0.0077 16.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE03939.1 - 0.00062 20.2 0.6 0.55 10.8 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE03939.1 - 0.0011 19.2 0.4 0.0055 17.0 0.4 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE03939.1 - 0.0021 18.3 0.8 5.2 7.7 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGE03939.1 - 0.0026 18.3 1.2 3.6 8.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE03939.1 - 0.0083 16.9 1.4 10 7.2 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE03939.1 - 0.04 14.1 1.1 0.28 11.5 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGE03939.1 - 0.076 13.1 0.3 0.88 9.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGE03939.1 - 0.64 10.1 6.6 0.82 9.8 0.3 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Spt4 PF06093.13 EGE03940.1 - 2.2e-32 111.0 0.2 2.6e-32 110.7 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EGE03940.1 - 0.06 13.3 0.1 0.092 12.7 0.1 1.4 1 1 0 1 1 1 0 Coronavirus gene 5 protein Aminotran_3 PF00202.21 EGE03941.1 - 8.9e-125 416.5 0.0 1e-124 416.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGE03941.1 - 0.0091 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Orbi_NS3 PF01616.16 EGE03941.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Orbivirus NS3 Bestrophin PF01062.21 EGE03942.1 - 1.5e-35 123.0 0.0 2.3e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GSH_synth_ATP PF03917.17 EGE03946.1 - 4.9e-134 446.8 0.0 5.6e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGE03946.1 - 3.5e-27 94.8 0.0 6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EGE03947.1 - 1.5e-46 158.7 1.2 3.1e-46 157.7 0.2 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE03947.1 - 1.4e-17 64.1 0.0 3.4e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03947.1 - 9.9e-08 32.2 0.0 3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGE03947.1 - 3.3e-05 23.2 0.0 9.5e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EGE03947.1 - 8.5e-05 22.3 0.0 0.041 13.6 0.0 2.7 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_1 PF00536.30 EGE03947.1 - 0.016 15.6 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGE03947.1 - 0.028 14.5 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RIX1 PF08167.12 EGE03948.1 - 5.4e-60 202.4 1.1 1.6e-59 200.8 1.1 1.9 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MBOAT_2 PF13813.6 EGE03949.1 - 6.7e-21 74.4 2.1 1.4e-20 73.4 2.1 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Big_4 PF07532.11 EGE03949.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) HXXEE PF13787.6 EGE03949.1 - 3.5 8.5 6.7 0.51 11.2 0.3 2.6 3 1 0 3 3 3 0 Protein of unknown function with HXXEE motif SNF2_N PF00176.23 EGE03951.1 - 9.1e-58 195.6 0.0 1.5e-57 194.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE03951.1 - 2.9e-15 56.6 0.0 2.6e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGE03951.1 - 6.4e-10 38.7 7.4 6.4e-10 38.7 7.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE03951.1 - 5.9e-09 36.1 6.9 5.9e-09 36.1 6.9 2.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGE03951.1 - 3.4e-08 33.2 8.1 3.4e-08 33.2 8.1 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE03951.1 - 5.3e-07 29.8 3.6 1.9e-06 28.0 3.6 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGE03951.1 - 1.7e-06 27.8 8.1 1.7e-06 27.8 8.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE03951.1 - 2.2e-06 27.6 6.8 6.3e-06 26.1 6.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGE03951.1 - 7.3e-06 25.6 2.8 7.3e-06 25.6 2.8 3.2 4 0 0 4 4 4 1 RING-like zinc finger zf-RING_5 PF14634.6 EGE03951.1 - 8.6e-06 25.6 5.1 8.6e-06 25.6 5.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGE03951.1 - 0.00015 21.5 8.7 0.00015 21.5 8.7 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 DEAD PF00270.29 EGE03951.1 - 0.00024 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.6 EGE03951.1 - 0.00047 20.2 8.5 0.0011 19.1 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGE03951.1 - 0.0045 16.8 4.6 0.01 15.6 4.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EGE03951.1 - 0.0078 16.4 0.1 0.048 13.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 EGE03951.1 - 0.064 13.3 1.8 0.28 11.3 1.8 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.17 EGE03952.1 - 1.2e-08 34.4 0.8 0.1 12.8 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE03952.1 - 2e-08 34.4 11.5 0.086 13.7 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE03952.1 - 6.8e-07 29.0 0.3 0.069 13.4 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE03952.1 - 2.3e-06 28.0 6.9 0.055 14.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE03952.1 - 0.00073 19.3 2.4 0.085 12.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE03952.1 - 0.0022 18.3 0.0 23 5.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGE03952.1 - 0.017 15.7 9.0 7.1 7.4 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE03952.1 - 2 9.3 3.6 8.7 7.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PLDc_2 PF13091.6 EGE03953.1 - 1.4e-15 57.4 0.0 5.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGE03953.1 - 8e-09 35.3 2.5 0.0025 17.9 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.14 EGE03954.1 - 8.8e-118 394.4 17.2 1e-117 394.2 17.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EGE03955.1 - 1.2e-15 57.6 0.4 1.8e-14 53.8 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE03955.1 - 4.6e-06 26.3 0.3 3.3e-05 23.5 0.2 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EGE03955.1 - 0.0027 17.1 0.1 0.0047 16.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGE03955.1 - 0.0079 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EGE03955.1 - 0.38 10.8 4.6 0.29 11.2 0.5 2.8 2 1 1 3 3 3 0 Dynamin family DNA_pol_phi PF04931.13 EGE03955.1 - 3.5 5.6 10.5 4.8 5.2 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2_jaz PF12171.8 EGE03956.1 - 0.039 14.2 0.3 0.25 11.7 0.0 2.5 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGE03956.1 - 0.15 13.0 7.2 3.1 8.9 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE03956.1 - 1 9.9 11.4 2.5 8.7 0.2 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE03957.1 - 1e-10 41.5 7.3 4e-10 39.7 3.0 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGE03957.1 - 2.2e-09 37.3 10.4 1.5e-06 28.4 3.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE03957.1 - 2.3e-07 31.0 9.5 2.6e-05 24.7 2.7 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE03957.1 - 1.1e-06 28.8 2.4 0.0023 18.1 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGE03957.1 - 1.2e-05 25.5 3.9 0.021 15.2 0.3 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 EGE03957.1 - 1.3e-05 25.6 5.8 7.4e-05 23.1 1.2 2.0 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger gag_pre-integrs PF13976.6 EGE03957.1 - 0.0035 17.2 1.1 0.048 13.5 0.1 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-BED PF02892.15 EGE03957.1 - 0.0036 17.3 5.9 0.094 12.7 1.3 2.2 1 1 1 2 2 2 2 BED zinc finger zf-RING_7 PF02591.15 EGE03957.1 - 0.008 16.3 0.5 0.64 10.3 0.1 2.2 2 0 0 2 2 2 1 C4-type zinc ribbon domain zf_UBZ PF18439.1 EGE03957.1 - 0.024 14.2 3.5 1.5 8.4 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YyzF PF14116.6 EGE03957.1 - 0.035 14.1 1.0 6.7 6.8 0.1 2.2 2 0 0 2 2 2 0 YyzF-like protein XPA_N PF01286.18 EGE03957.1 - 0.056 13.5 2.2 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-DBF PF07535.12 EGE03957.1 - 0.059 13.5 4.0 4.2 7.6 0.5 2.2 2 0 0 2 2 2 0 DBF zinc finger zf-FCS PF06467.14 EGE03957.1 - 0.07 13.1 2.9 0.2 11.6 3.0 1.7 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATPase-cat_bd PF12156.8 EGE03957.1 - 0.082 13.7 2.6 0.12 13.1 2.6 1.3 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-C2H2_6 PF13912.6 EGE03957.1 - 0.12 12.4 9.3 0.79 9.8 0.9 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGE03957.1 - 0.13 12.2 10.1 1.3 9.0 0.7 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 EGE03957.1 - 0.26 11.4 5.9 1.3 9.2 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Elf1 PF05129.13 EGE03957.1 - 0.72 9.9 6.8 3.8 7.6 6.8 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-AN1 PF01428.16 EGE03957.1 - 1.9 8.7 9.7 8 6.7 2.1 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger Pkinase PF00069.25 EGE03958.1 - 1.3e-69 234.5 0.0 1e-68 231.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03958.1 - 1.9e-47 161.8 0.0 4.4e-47 160.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EGE03958.1 - 3.6e-27 94.6 0.0 7.1e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EGE03958.1 - 3.8e-16 59.3 0.1 8.5e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGE03958.1 - 1.1e-13 51.1 0.0 2.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EGE03958.1 - 5.6e-08 32.5 0.0 0.00026 20.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 EGE03958.1 - 0.0003 21.4 0.0 0.00057 20.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EGE03958.1 - 0.003 16.4 0.1 0.003 16.4 0.1 1.9 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGE03958.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_4 PF18017.1 EGE03958.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L5_C PF00673.21 EGE03959.1 - 2.3e-28 98.2 0.0 4.4e-28 97.3 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGE03959.1 - 1.2e-05 25.5 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Ligase_CoA PF00549.19 EGE03960.1 - 2e-22 79.6 0.2 3.6e-22 78.8 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EGE03960.1 - 2.6e-21 76.1 2.7 2.6e-21 76.1 2.7 2.1 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EGE03960.1 - 4.3e-08 33.1 0.1 9.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGE03960.1 - 3.7e-05 24.2 0.1 8.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM_C PF16199.5 EGE03961.1 - 1.6e-32 111.3 0.1 4.6e-32 109.9 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGE03961.1 - 1.8e-19 70.7 0.1 7e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGE03961.1 - 3.2e-10 40.3 0.0 6.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE03961.1 - 1.4e-06 28.3 0.2 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE03961.1 - 0.089 13.2 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SirB PF04247.12 EGE03962.1 - 0.052 13.6 2.7 0.06 13.4 2.7 1.2 1 0 0 1 1 1 0 Invasion gene expression up-regulator, SirB DUF3810 PF12725.7 EGE03962.1 - 0.08 12.3 0.1 0.09 12.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) His_biosynth PF00977.21 EGE03963.1 - 3.5e-33 115.0 0.0 4.1e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGE03963.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EGE03964.1 - 5.4e-12 46.2 5.9 1.2e-11 45.0 5.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) STE PF02200.16 EGE03966.1 - 1.6e-56 189.4 0.1 2.8e-56 188.7 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EGE03966.1 - 2.4e-11 43.4 10.8 6.7e-07 29.4 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE03966.1 - 2.3e-09 37.3 4.2 2.3e-09 37.3 4.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE03966.1 - 1.2e-07 31.9 8.8 0.00099 19.8 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGE03966.1 - 0.0026 17.7 0.3 0.0026 17.7 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE03966.1 - 0.0071 16.6 0.3 0.12 12.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 EGE03966.1 - 0.039 14.6 1.6 0.1 13.3 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_9 PF14369.6 EGE03966.1 - 0.063 13.5 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 EGE03966.1 - 0.092 13.1 3.5 0.1 12.9 0.3 2.3 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 EGE03966.1 - 0.14 12.4 0.4 0.33 11.2 0.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-TRAF PF02176.18 EGE03966.1 - 0.3 11.8 2.9 0.53 11.0 2.9 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.6 EGE03966.1 - 2.2 8.3 4.3 5.3 7.0 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.6 EGE03966.1 - 6.2 6.7 10.4 14 5.5 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MFS_2 PF13347.6 EGE03967.1 - 1.5e-08 33.7 2.7 1.5e-08 33.7 2.7 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 EGE03967.1 - 1.7e-07 30.5 14.0 1.7e-07 30.5 14.0 3.1 3 1 0 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 EGE03967.1 - 0.00041 19.5 1.3 0.00076 18.6 1.3 1.4 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.21 EGE03969.1 - 7.9e-72 242.1 35.8 1e-71 241.8 35.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TYA PF01021.19 EGE03969.1 - 0.049 14.0 0.4 0.091 13.1 0.4 1.3 1 0 0 1 1 1 0 TYA transposon protein Kelch_6 PF13964.6 EGE03969.1 - 0.15 12.4 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Kelch motif CrgA PF06781.12 EGE03969.1 - 1.8 8.7 0.0 1.8 8.7 0.0 2.9 4 0 0 4 4 4 0 Cell division protein CrgA Pox_EPC_I2-L1 PF12575.8 EGE03969.1 - 1.8 8.9 0.0 1.8 8.9 0.0 3.6 4 1 0 4 4 4 0 Poxvirus entry protein complex L1 and I2 SNF2_N PF00176.23 EGE03970.1 - 1.2e-64 218.2 2.5 1.2e-64 218.2 2.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EGE03970.1 - 3.5e-48 163.4 21.3 3.5e-48 163.4 21.3 5.4 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.31 EGE03970.1 - 4.6e-19 68.8 0.0 1.3e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE03970.1 - 1.5e-06 28.3 3.4 3.4e-06 27.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE03970.1 - 0.00019 21.3 0.0 0.00053 19.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EGE03970.1 - 0.011 14.9 2.7 0.058 12.6 0.0 3.1 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 baeRF_family12 PF18856.1 EGE03970.1 - 0.015 15.9 0.2 0.015 15.9 0.2 5.4 6 1 0 6 6 6 0 Bacterial archaeo-eukaryotic release factor family 12 Orthopox_F8 PF05886.11 EGE03970.1 - 1.3 9.2 9.7 5.7 7.2 9.7 2.1 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Pep3_Vps18 PF05131.14 EGE03971.1 - 3e-45 153.7 0.0 8.4e-45 152.2 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGE03971.1 - 2.3e-11 43.8 2.1 6.9e-06 26.0 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EGE03971.1 - 0.00018 21.0 0.2 0.00037 20.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGE03971.1 - 0.00096 19.0 1.0 0.0024 17.6 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE03971.1 - 0.001 19.0 0.8 0.0024 17.8 0.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.9 EGE03971.1 - 0.0019 18.5 1.0 0.0098 16.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 EGE03971.1 - 0.002 17.9 4.3 0.002 17.9 4.3 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EGE03971.1 - 0.0047 17.2 0.8 0.012 15.9 0.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGE03971.1 - 0.038 14.0 0.8 0.098 12.7 0.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 EGE03971.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EGE03971.1 - 0.059 13.7 0.8 0.29 11.4 0.6 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGE03971.1 - 0.22 11.4 2.5 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NOA36 PF06524.12 EGE03972.1 - 0.00022 20.7 4.3 0.00026 20.4 4.3 1.2 1 0 0 1 1 1 1 NOA36 protein DUF2237 PF09996.9 EGE03972.1 - 0.0094 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) CENP-B_dimeris PF09026.10 EGE03972.1 - 0.026 14.9 11.4 0.051 14.0 11.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EGE03972.1 - 1 7.5 4.2 1.1 7.3 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EGE03972.1 - 1.4 8.6 9.6 1.7 8.3 9.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EGE03972.1 - 1.4 7.4 2.5 1.6 7.2 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EGE03972.1 - 3.4 5.6 9.4 4.5 5.3 9.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 EGE03972.1 - 5.3 7.3 10.2 15 5.9 9.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 EGE03972.1 - 5.9 5.9 15.5 11 5.1 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 EGE03973.1 - 1.2e-51 175.7 0.0 1.7e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE03973.1 - 6.6e-33 114.1 0.0 9.7e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE03973.1 - 3.6e-10 39.7 0.0 4.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGE03973.1 - 0.058 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE03973.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sad1_UNC PF07738.13 EGE03974.1 - 3.3e-31 108.0 0.0 5.8e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 EGE03974.1 - 0.0079 15.9 0.8 0.029 14.1 0.8 1.9 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain TraU PF06834.11 EGE03974.1 - 0.053 12.8 1.4 0.16 11.2 1.4 1.7 1 1 0 1 1 1 0 TraU protein SPG4 PF17325.2 EGE03974.1 - 7.2 7.7 8.9 0.84 10.8 2.8 2.6 2 0 0 2 2 2 0 Stationary phase protein 4 Spo12 PF05032.12 EGE03975.1 - 2.9e-14 52.7 0.4 7e-14 51.4 0.4 1.7 1 0 0 1 1 1 1 Spo12 family IGPD PF00475.18 EGE03976.1 - 2.2e-57 193.4 1.3 3.3e-57 192.9 1.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Acyl-CoA_dh_1 PF00441.24 EGE03977.1 - 2.5e-31 108.9 2.2 4.1e-31 108.2 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGE03977.1 - 2.4e-19 69.3 0.0 4.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGE03977.1 - 4e-14 53.2 0.3 1e-13 51.9 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGE03977.1 - 5.8e-14 52.5 5.9 1e-13 51.7 5.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EST1_DNA_bind PF10373.9 EGE03978.1 - 3.7e-58 197.2 3.7 5.6e-58 196.6 3.7 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EGE03978.1 - 6.1e-23 82.0 0.4 2.2e-22 80.2 0.1 2.1 3 0 0 3 3 3 1 Telomerase activating protein Est1 FWWh PF14922.6 EGE03978.1 - 0.092 12.7 0.1 0.31 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function PfkB PF00294.24 EGE03979.1 - 7e-67 225.9 0.1 8.5e-67 225.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGE03979.1 - 2.4e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PS_pyruv_trans PF04230.13 EGE03979.1 - 0.0035 17.3 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF5450 PF17529.2 EGE03979.1 - 0.05 13.7 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5450) CbiK PF06180.11 EGE03979.1 - 0.16 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF1770 PF08589.10 EGE03980.1 - 1.2e-17 64.7 0.0 1.6e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EGE03981.1 - 7.5e-08 31.7 0.0 1.7e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 EGE03982.1 - 1.6e-41 141.4 5.9 2.8e-41 140.6 5.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGE03982.1 - 3.8e-13 49.2 0.1 9.6e-13 47.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ada_Zn_binding PF02805.16 EGE03983.1 - 2.2e-29 101.3 4.3 4.1e-29 100.4 4.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EGE03983.1 - 3e-07 30.4 0.0 7.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EGE03983.1 - 0.00037 20.7 0.0 0.00083 19.6 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain BAR PF03114.18 EGE03984.1 - 1.8e-45 155.5 8.4 2.1e-45 155.2 8.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EGE03984.1 - 4.1e-08 32.7 4.5 5.4e-08 32.3 4.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking AAA_23 PF13476.6 EGE03984.1 - 0.49 10.9 4.4 0.77 10.2 4.4 1.4 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 EGE03984.1 - 1.5 9.4 12.5 2.2 8.8 10.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 EGE03984.1 - 4.4 6.5 5.4 7.7 5.7 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein SNF2_N PF00176.23 EGE03985.1 - 2e-70 237.3 0.6 2e-70 237.3 0.6 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EGE03985.1 - 1.3e-25 89.3 0.4 1.4e-24 85.9 0.7 2.4 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 EGE03985.1 - 6.2e-20 71.6 0.3 1.8e-18 66.9 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EGE03985.1 - 4.6e-19 68.5 11.0 4.6e-19 68.5 11.0 3.3 4 0 0 4 4 4 1 HSA SnAC PF14619.6 EGE03985.1 - 1.2e-13 51.4 0.2 1.2e-13 51.4 0.2 3.7 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EGE03985.1 - 2.5e-13 49.5 4.8 2.5e-13 49.5 4.8 2.7 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 EGE03985.1 - 2.5e-09 37.4 0.4 1.1e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DehI PF10778.9 EGE03985.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.3 2 1 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Vps54 PF07928.12 EGE03986.1 - 3.2e-38 131.2 0.2 1.2e-37 129.4 0.2 2.1 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 EGE03986.1 - 1.9e-05 24.6 0.1 5e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) p450 PF00067.22 EGE03987.1 - 3.7e-66 223.8 0.0 5.1e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stirrup PF09061.6 EGE03987.1 - 0.099 12.9 0.3 28 5.0 0.1 3.2 3 0 0 3 3 3 0 Stirrup p450 PF00067.22 EGE03988.1 - 3.3e-22 78.9 0.0 4.3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.19 EGE03988.1 - 0.013 15.7 0.5 0.034 14.4 0.5 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Aminotran_1_2 PF00155.21 EGE03990.1 - 7.6e-86 288.5 0.0 1.4e-85 287.7 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE03990.1 - 2.4e-06 26.3 0.0 4.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGE03990.1 - 1.4e-05 24.6 0.1 2.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGE03990.1 - 0.0011 18.0 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGE03990.1 - 0.023 14.0 0.5 0.071 12.4 0.5 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase NitrOD2 PF18550.1 EGE03990.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Nitrososphaera output domain 2 RNA_pol_I_A49 PF06870.12 EGE03991.1 - 1.7e-69 234.6 0.2 2e-69 234.3 0.2 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor GATase PF00117.28 EGE03992.1 - 1e-47 162.4 0.0 4.8e-47 160.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EGE03992.1 - 2.6e-44 150.1 0.0 1.3e-43 147.9 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EGE03992.1 - 4e-05 23.5 0.3 0.0013 18.6 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 Leader_CPA1 PF08252.11 EGE03992.1 - 0.00082 18.7 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide Imm9 PF15587.6 EGE03992.1 - 0.002 17.8 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 9 DJ-1_PfpI PF01965.24 EGE03992.1 - 0.052 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Spem1 PF15670.5 EGE03993.1 - 0.0046 16.6 2.2 0.0055 16.3 2.2 1.0 1 0 0 1 1 1 1 Spermatid maturation protein 1 FUSC PF04632.12 EGE03993.1 - 0.1 11.1 2.0 0.12 10.9 2.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Gyro_capsid PF04162.12 EGE03993.1 - 1.2 7.6 8.1 1.3 7.4 8.1 1.1 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Peptidase_S10 PF00450.22 EGE03994.1 - 4.2e-84 283.4 4.5 8.8e-84 282.3 4.5 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.7 EGE03995.1 - 4.1e-09 37.2 0.0 5.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE03995.1 - 0.0063 16.7 0.0 0.11 12.8 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PARP PF00644.20 EGE03996.1 - 1.3e-59 201.1 0.0 1.3e-59 201.1 0.0 3.2 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGE03996.1 - 2.2e-42 144.4 0.1 3.8e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGE03996.1 - 9.7e-23 80.0 0.3 9.7e-23 80.0 0.3 2.4 3 0 0 3 3 3 1 WGR domain BRCT PF00533.26 EGE03996.1 - 1e-09 38.6 0.0 3.6e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGE03996.1 - 8.3e-08 32.1 0.1 1.8e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGE03996.1 - 1.5e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain GAGA_bind PF06217.12 EGE03996.1 - 0.26 11.5 16.2 0.29 11.4 8.0 2.5 2 0 0 2 2 2 0 GAGA binding protein-like family GREB1 PF15782.5 EGE03996.1 - 1.3 6.0 10.3 2.2 5.3 10.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hamartin PF04388.12 EGE03996.1 - 6.5 5.3 16.7 8.9 4.8 16.7 1.1 1 0 0 1 1 1 0 Hamartin protein Mitofilin PF09731.9 EGE03996.1 - 9.5 4.9 29.6 0.12 11.2 19.3 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Ysc84 PF04366.12 EGE03997.1 - 1.7e-45 153.9 0.0 3.1e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Antimicrobial10 PF08105.11 EGE03997.1 - 0.026 14.6 0.2 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Metchnikowin family eIF-3_zeta PF05091.12 EGE03997.1 - 6.1 5.7 12.7 10 5.0 12.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ETF PF01012.21 EGE03998.1 - 8.8e-41 139.8 0.3 1.1e-40 139.5 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.25 EGE03999.1 - 6.2e-31 107.5 0.0 2.3e-30 105.7 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EGE03999.1 - 1.9e-30 106.1 0.0 2.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGE03999.1 - 5.2e-15 56.0 0.0 1.2e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGE03999.1 - 0.12 12.6 0.2 2.8 8.2 0.0 2.8 2 1 1 3 3 3 0 Flavodoxin domain FAD_binding_6 PF00970.24 EGE03999.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_3 PF12641.7 EGE03999.1 - 0.18 11.5 0.0 1.4 8.6 0.0 2.0 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 EGE04001.1 - 4.7e-64 216.7 12.9 6e-64 216.4 12.9 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EGE04001.1 - 0.0082 16.2 3.2 0.0081 16.2 3.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit JAB PF01398.21 EGE04003.1 - 1.4e-11 44.4 0.4 2.7e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGE04003.1 - 2.9e-11 43.8 0.9 8.1e-11 42.3 0.9 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF4718 PF15842.5 EGE04003.1 - 0.17 11.7 0.7 0.32 10.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) SAP PF02037.27 EGE04004.1 - 3.2e-09 36.3 0.1 6.1e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EGE04004.1 - 3e-07 30.6 0.0 3e-07 30.6 0.0 3.7 2 1 0 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Pinin_SDK_memA PF04696.13 EGE04004.1 - 0.33 11.0 0.0 0.33 11.0 0.0 3.2 2 1 1 3 3 3 0 pinin/SDK/memA/ protein conserved region MAJIN PF15077.6 EGE04004.1 - 2.5 7.8 8.8 4.4 7.0 8.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1772 PF08592.11 EGE04005.1 - 0.00049 20.4 1.7 0.0038 17.5 1.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF401 PF04165.12 EGE04005.1 - 0.18 11.1 1.7 0.23 10.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF401) adh_short_C2 PF13561.6 EGE04006.1 - 2.2e-35 122.3 6.5 7.9e-35 120.5 6.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE04006.1 - 2.5e-28 98.9 2.5 4e-28 98.2 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE04006.1 - 1.6e-06 28.2 1.6 4.9e-06 26.6 0.5 2.0 2 0 0 2 2 2 1 KR domain HMMR_N PF15905.5 EGE04007.1 - 0.00069 19.2 7.3 0.00069 19.2 7.3 2.6 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Armet PF10208.9 EGE04007.1 - 0.11 12.4 0.5 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding XkdW PF09636.10 EGE04007.1 - 0.4 10.8 3.7 1.1 9.4 0.2 3.1 3 0 0 3 3 3 0 XkdW protein CREPT PF16566.5 EGE04007.1 - 2 8.6 12.6 0.21 11.8 3.6 2.6 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS5 PF14817.6 EGE04007.1 - 4.5 5.9 25.3 0.98 8.1 8.3 2.5 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 5 AAA_13 PF13166.6 EGE04007.1 - 7.5 5.1 13.3 23 3.5 13.5 1.7 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.11 EGE04007.1 - 7.9 6.5 13.8 1.4e+02 2.4 13.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 EGE04007.1 - 8.2 6.7 9.2 4.3 7.6 1.5 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EGE04007.1 - 9.8 5.0 18.4 1 8.2 8.1 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein TssO PF17561.2 EGE04008.1 - 0.068 13.3 0.4 0.085 13.0 0.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO CRPA PF05745.11 EGE04009.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) RabGAP-TBC PF00566.18 EGE04010.1 - 8.8e-47 159.5 0.0 1.4e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGE04010.1 - 1.1e-06 28.1 2.9 0.01 15.7 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGE04010.1 - 1.8e-05 24.0 1.0 0.1 12.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGE04010.1 - 0.0011 19.4 1.3 0.014 15.9 0.1 3.1 1 1 2 3 3 3 3 EF-hand domain pair GRAM PF02893.20 EGE04010.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF4611 PF15387.6 EGE04010.1 - 2 8.7 11.9 2.9 8.2 1.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CNH PF00780.22 EGE04011.1 - 4.2e-65 220.1 0.0 6.4e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EGE04011.1 - 7.4e-34 117.6 1.4 1.4e-33 116.7 1.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EGE04011.1 - 3.6e-13 49.8 0.0 1.2e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGE04011.1 - 0.0044 17.5 0.0 0.014 15.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 EGE04011.1 - 0.013 15.3 0.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 PH domain 2OG-FeII_Oxy_2 PF13532.6 EGE04012.1 - 1.1e-28 100.8 0.0 2.4e-28 99.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 EGE04013.1 - 4.9e-81 272.5 0.0 6.4e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE04013.1 - 3e-14 53.7 0.4 7.8e-14 52.4 0.4 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EGE04014.1 - 3.1e-19 68.9 8.0 0.0037 18.1 0.0 8.4 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04014.1 - 8.1e-07 29.3 0.0 0.0011 19.2 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE04014.1 - 0.03 13.3 0.3 0.28 10.1 0.1 2.5 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EGE04014.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus NDUF_B12 PF08122.12 EGE04015.1 - 1e-10 41.5 6.0 3e-10 40.0 3.2 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 EGE04016.1 - 2e-24 86.4 0.0 3.3e-11 42.9 0.0 2.7 3 0 0 3 3 3 2 CAF1 family ribonuclease Siva PF05458.12 EGE04016.1 - 0.18 11.5 0.7 21 4.8 1.4 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Cu_amine_oxid PF01179.20 EGE04017.1 - 1.8e-161 537.6 0.1 2.2e-161 537.4 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EGE04017.1 - 3.4e-18 65.9 0.1 6.9e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EGE04017.1 - 1.1e-14 54.5 0.0 2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Asp PF00026.23 EGE04018.1 - 9.4e-51 173.1 0.1 1.1e-50 172.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGE04018.1 - 0.0012 18.6 0.0 0.022 14.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGE04018.1 - 0.023 14.9 0.2 0.31 11.3 0.0 2.6 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE04018.1 - 0.21 12.3 0.7 12 6.6 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease TPR_2 PF07719.17 EGE04019.1 - 5.8e-06 26.0 7.7 0.011 15.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE04019.1 - 2.9e-05 23.7 3.2 0.47 10.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE04019.1 - 0.00069 19.9 5.1 0.098 13.0 0.0 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE04019.1 - 0.0066 16.6 3.8 0.75 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE04019.1 - 0.04 14.4 2.9 0.45 11.1 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGE04019.1 - 0.06 13.4 3.2 6.9 6.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE04019.1 - 0.068 13.4 0.3 0.3 11.3 0.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGE04019.1 - 0.59 10.8 4.8 1.6e+02 3.0 5.7 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGE04019.1 - 1.2 9.1 9.1 17 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat VASt PF16016.5 EGE04020.1 - 3.4e-34 118.5 0.0 6e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGE04020.1 - 3.8e-21 75.1 0.0 7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Axin_b-cat_bind PF08833.10 EGE04020.1 - 0.052 13.6 0.2 0.052 13.6 0.2 2.9 4 0 0 4 4 4 0 Axin beta-catenin binding domain ABC_tran_CTD PF16326.5 EGE04021.1 - 0.065 13.5 3.6 0.3 11.3 3.6 2.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 EGE04021.1 - 1.5 8.9 10.5 4.2 7.5 5.9 2.6 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 EGE04021.1 - 2.1 8.8 6.5 1.3 9.5 2.4 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mg_trans_NIPA PF05653.14 EGE04022.1 - 3.4e-62 210.2 13.8 7.9e-60 202.5 10.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EGE04022.1 - 0.00028 21.1 1.3 0.00028 21.1 1.3 3.7 3 1 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EGE04022.1 - 0.00056 19.5 4.5 0.00085 18.9 3.9 1.5 1 1 0 1 1 1 1 Solute carrier family 35 Trp_oprn_chp PF09534.10 EGE04022.1 - 0.0047 16.7 0.3 0.94 9.2 0.4 2.7 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ctr PF04145.15 EGE04022.1 - 0.13 12.9 0.3 16 6.1 0.1 3.2 2 2 0 2 2 2 0 Ctr copper transporter family DoxX_2 PF13564.6 EGE04022.1 - 0.17 12.0 6.1 2.2 8.5 0.6 2.5 2 0 0 2 2 2 0 DoxX-like family DUF2198 PF09964.9 EGE04022.1 - 1 9.4 5.8 0.28 11.3 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) TssN PF17555.2 EGE04022.1 - 6.9 6.0 9.0 11 5.3 9.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN BaxI_1 PF12811.7 EGE04022.1 - 7.3 6.1 12.5 1.1e+02 2.2 12.5 2.4 1 1 0 1 1 1 0 Bax inhibitor 1 like WD40 PF00400.32 EGE04023.1 - 2.2e-12 47.3 11.7 0.0086 16.9 0.2 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04023.1 - 0.0051 17.1 0.0 2.3 8.6 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE04023.1 - 0.14 12.1 0.0 2.2 8.1 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A AAA PF00004.29 EGE04024.1 - 7.7e-18 65.2 0.1 1.9e-17 63.9 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE04024.1 - 1.7e-10 40.5 0.7 3.7e-10 39.4 0.7 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGE04024.1 - 1.3e-09 37.8 0.1 2.3e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain DUF815 PF05673.13 EGE04024.1 - 0.0008 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGE04024.1 - 0.0023 18.2 0.5 0.0056 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGE04024.1 - 0.0043 16.3 0.1 0.0073 15.6 0.1 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EGE04024.1 - 0.0053 17.2 0.1 0.013 15.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EGE04024.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 EGE04024.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE04024.1 - 0.017 15.4 0.8 0.038 14.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGE04024.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGE04024.1 - 0.042 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGE04024.1 - 0.042 13.6 2.1 0.44 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGE04024.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGE04024.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGE04024.1 - 0.087 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EGE04024.1 - 0.13 11.7 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 EGE04024.1 - 0.14 11.9 0.7 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Zeta_toxin PF06414.12 EGE04024.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EGE04024.1 - 0.16 12.3 0.8 0.32 11.3 0.8 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGE04024.1 - 0.24 11.9 1.1 0.46 11.0 0.2 2.0 2 1 0 2 2 1 0 ABC transporter APH PF01636.23 EGE04025.1 - 1.9e-14 54.2 0.0 1.1e-13 51.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGE04025.1 - 0.049 13.0 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.11 EGE04025.1 - 0.053 12.4 0.1 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UQ_con PF00179.26 EGE04026.1 - 1.8e-43 147.6 0.0 2.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EGE04026.1 - 3.9e-06 26.6 0.0 8.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EGE04026.1 - 5.6e-05 22.9 0.0 0.00011 21.9 0.0 1.4 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EGE04026.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain Cyclin_C_2 PF16899.5 EGE04027.1 - 5.1e-36 123.2 0.0 4.3e-32 110.6 0.0 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EGE04027.1 - 0.00038 20.2 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ABC_tran PF00005.27 EGE04028.1 - 7.9e-48 162.5 0.0 2.8e-23 82.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGE04028.1 - 1.9e-21 75.9 3.2 1.9e-21 75.9 3.2 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EGE04028.1 - 9.3e-19 68.3 1.7 0.00098 19.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE04028.1 - 2e-11 43.8 0.3 0.00091 18.7 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE04028.1 - 3.7e-08 33.0 1.2 0.0027 17.4 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGE04028.1 - 1.1e-07 32.5 5.2 0.029 14.9 0.2 3.9 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 EGE04028.1 - 4.7e-07 29.8 0.0 0.02 14.6 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGE04028.1 - 1.6e-06 28.1 0.3 0.0055 16.6 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGE04028.1 - 1.9e-06 28.0 0.0 0.013 15.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EGE04028.1 - 2.4e-06 28.1 0.1 0.074 13.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EGE04028.1 - 4.1e-06 27.3 0.0 0.027 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGE04028.1 - 6.1e-05 23.3 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EGE04028.1 - 6.1e-05 22.7 0.0 0.078 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EGE04028.1 - 0.00012 22.4 0.0 0.056 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGE04028.1 - 0.00016 21.6 0.2 0.49 10.3 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 EGE04028.1 - 0.00023 21.6 0.0 1 9.8 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGE04028.1 - 0.0003 21.0 2.0 0.2 11.8 0.1 3.3 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.14 EGE04028.1 - 0.00033 20.7 0.1 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGE04028.1 - 0.00034 21.0 0.7 1.5 9.2 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Dynamin_N PF00350.23 EGE04028.1 - 0.00035 20.7 2.6 0.64 10.1 0.0 3.6 3 1 0 3 3 3 1 Dynamin family NB-ARC PF00931.22 EGE04028.1 - 0.00061 19.0 0.1 2.6 7.2 0.0 3.3 3 0 0 3 3 3 2 NB-ARC domain Roc PF08477.13 EGE04028.1 - 0.001 19.3 0.1 3.4 7.9 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGE04028.1 - 0.004 16.9 2.9 2.4 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.13 EGE04028.1 - 0.0046 16.2 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGE04028.1 - 0.0051 16.8 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGE04028.1 - 0.0053 16.7 0.2 2.2 8.1 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain DUF2813 PF11398.8 EGE04028.1 - 0.0059 15.9 0.7 0.99 8.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2813) AAA_7 PF12775.7 EGE04028.1 - 0.012 15.1 1.0 2 7.9 0.0 3.0 3 0 0 3 3 3 0 P-loop containing dynein motor region MCM PF00493.23 EGE04028.1 - 0.016 14.3 0.1 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 EGE04028.1 - 0.019 14.9 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 EGE04028.1 - 0.032 14.6 0.2 34 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain GST_C_3 PF14497.6 EGE04028.1 - 0.033 14.4 0.2 0.08 13.1 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA_25 PF13481.6 EGE04028.1 - 0.036 13.7 0.1 0.97 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 EGE04028.1 - 0.041 13.5 0.0 0.23 11.1 0.0 2.1 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 EGE04028.1 - 0.059 13.3 0.2 11 5.8 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Ras PF00071.22 EGE04028.1 - 0.069 12.7 0.0 6.9 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras family DAP3 PF10236.9 EGE04028.1 - 0.08 12.1 0.9 5.2 6.1 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.9 EGE04028.1 - 0.085 11.6 0.3 20 3.8 0.0 3.3 3 1 0 3 3 3 0 Predicted ATPase of the ABC class PduV-EutP PF10662.9 EGE04028.1 - 0.097 12.4 2.0 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EGE04028.1 - 0.1 12.3 0.0 3.1 7.5 0.0 2.9 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGE04028.1 - 0.1 12.3 2.0 3.3 7.4 0.1 3.1 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.18 EGE04028.1 - 0.11 12.0 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B p450 PF00067.22 EGE04029.1 - 2.2e-29 102.6 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEP PF00610.21 EGE04029.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SLC3A2_N PF16028.5 EGE04030.1 - 0.053 13.1 0.5 0.053 13.1 0.5 2.4 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus DUF4267 PF14087.6 EGE04031.1 - 1.1e-24 86.7 2.1 1.2e-24 86.5 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MFS_1 PF07690.16 EGE04032.1 - 5.1e-37 127.6 55.8 1.5e-36 126.0 54.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04032.1 - 5.2e-16 58.6 9.6 5.2e-16 58.6 9.6 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGE04032.1 - 1.2e-14 53.7 14.8 2e-14 52.9 14.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3522 PF12036.8 EGE04032.1 - 1.4 9.2 6.5 0.11 12.8 0.5 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) HPP PF04982.13 EGE04033.1 - 3.3e-40 137.0 7.9 6e-40 136.2 7.9 1.4 1 0 0 1 1 1 1 HPP family DUF3377 PF11857.8 EGE04033.1 - 0.01 15.7 0.5 0.029 14.3 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF599 PF04654.12 EGE04033.1 - 0.031 13.7 2.0 3.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Yip1 PF04893.17 EGE04033.1 - 0.072 12.8 11.3 1.8 8.2 0.7 2.6 1 1 2 3 3 3 0 Yip1 domain DUF1772 PF08592.11 EGE04033.1 - 5.5 7.3 7.3 2.3 8.5 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF1924 PF09086.11 EGE04035.1 - 0.04 14.3 0.1 0.081 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) GFO_IDH_MocA PF01408.22 EGE04036.1 - 3.3e-23 82.8 0.0 5.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGE04036.1 - 1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGE04036.1 - 9.5e-05 23.0 0.1 0.00018 22.2 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EGE04036.1 - 0.00054 20.1 0.0 0.00081 19.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus IF-2B PF01008.17 EGE04036.1 - 0.033 13.4 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family CoA_binding PF02629.19 EGE04036.1 - 0.057 14.1 0.2 0.14 12.8 0.1 1.8 2 0 0 2 2 2 0 CoA binding domain DUF3435 PF11917.8 EGE04038.1 - 0.0061 15.5 0.0 0.0077 15.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-RING_2 PF13639.6 EGE04039.1 - 1.1e-10 41.7 7.2 1.1e-10 41.7 7.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE04039.1 - 2.4e-10 40.1 6.6 2.4e-10 40.1 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE04039.1 - 8.2e-09 35.6 12.0 2.5e-08 34.1 10.4 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGE04039.1 - 3.3e-08 33.3 4.2 3.3e-08 33.3 4.2 2.5 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGE04039.1 - 1.5e-07 31.3 9.8 2.4e-07 30.7 2.1 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGE04039.1 - 3.5e-07 30.0 1.9 3.5e-07 30.0 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE04039.1 - 1.3e-06 28.2 5.5 1.3e-06 28.2 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGE04039.1 - 5.2e-06 26.4 4.8 1.4e-05 25.0 4.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGE04039.1 - 3.7e-05 23.2 3.4 7.4e-05 22.3 3.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGE04039.1 - 8.2e-05 22.3 6.0 0.0002 21.1 3.5 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 EGE04039.1 - 0.009 15.8 3.3 0.009 15.8 3.3 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EGE04039.1 - 0.016 15.3 4.4 0.049 13.8 4.4 1.9 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EGE04039.1 - 0.021 14.7 1.3 0.021 14.7 1.3 3.1 3 1 1 4 4 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGE04039.1 - 0.053 13.7 6.4 0.1 12.8 3.1 3.0 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Zn-C2H2_12 PF18112.1 EGE04039.1 - 0.34 11.4 2.5 4.1 8.0 0.2 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 EGE04039.1 - 0.53 10.2 1.6 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-P11 PF03854.14 EGE04039.1 - 0.65 9.7 3.7 2.7 7.7 0.4 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-C3H2C3 PF17122.5 EGE04039.1 - 1.1 9.3 7.2 0.45 10.6 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger zf-RING-like PF08746.11 EGE04039.1 - 1.2 9.5 7.0 0.19 12.1 2.3 2.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 EGE04039.1 - 2.7 8.0 12.4 0.18 11.8 1.8 3.0 4 0 0 4 4 3 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 EGE04039.1 - 5.3 7.3 8.2 24 5.2 8.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGE04039.1 - 7.1 6.6 9.6 0.88 9.5 3.9 2.4 2 1 0 2 2 2 0 PHD-finger T3SS_needle_E PF08988.10 EGE04043.1 - 0.0083 16.2 1.0 0.019 15.1 1.0 1.7 1 0 0 1 1 1 1 Type III secretion system, cytoplasmic E component of needle Radial_spoke PF04712.12 EGE04043.1 - 0.043 12.8 0.1 0.047 12.6 0.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3723 PF12520.8 EGE04044.1 - 2.6e-43 148.5 0.6 1.4e-40 139.5 0.4 6.0 2 2 1 3 3 3 2 Protein of unknown function (DUF3723) DUF3552 PF12072.8 EGE04044.1 - 5.8e-07 29.1 75.9 1.5e-05 24.5 34.6 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3552) DUF390 PF04094.14 EGE04044.1 - 0.61 8.3 13.9 0.98 7.6 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF2070 PF09843.9 EGE04045.1 - 0.0038 15.6 0.1 0.0048 15.3 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) APG5 PF04106.12 EGE04048.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 Autophagy protein Apg5 Gemini_AL1 PF00799.20 EGE04049.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain DUF4865 PF16157.5 EGE04052.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) EST1_DNA_bind PF10373.9 EGE04053.1 - 0.00077 19.0 0.2 0.0018 17.8 0.2 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain YkyA PF10368.9 EGE04054.1 - 0.03 14.0 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF1590 PF07629.11 EGE04054.1 - 0.034 14.0 0.1 0.067 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) DUF2841 PF11001.8 EGE04057.1 - 5.1e-48 162.2 0.1 8.3e-48 161.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) zf-H2C2_2 PF13465.6 EGE04059.1 - 4.3e-10 39.6 32.7 0.0034 17.7 1.5 5.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 EGE04059.1 - 1.4e-09 37.9 35.6 0.015 15.7 1.3 5.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE04059.1 - 5.6e-08 33.0 29.6 0.15 13.0 1.9 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGE04059.1 - 0.092 13.4 13.3 0.28 11.8 2.9 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats FXa_inhibition PF14670.6 EGE04059.1 - 0.097 13.0 5.6 7.3 7.0 0.1 3.2 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site zf-TRAF PF02176.18 EGE04059.1 - 0.13 13.0 15.2 2.9 8.7 1.3 3.7 1 1 3 4 4 4 0 TRAF-type zinc finger ARS2 PF04959.13 EGE04059.1 - 0.18 12.2 16.9 0.93 9.8 0.4 4.1 1 1 2 4 4 4 0 Arsenite-resistance protein 2 zinc_ribbon_15 PF17032.5 EGE04059.1 - 0.59 10.9 21.2 0.66 10.8 3.3 3.2 1 1 4 5 5 5 0 zinc-ribbon family FhuF_C PF11575.8 EGE04059.1 - 1 9.3 3.5 85 3.2 0.1 3.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Ephrin_rec_like PF07699.13 EGE04059.1 - 1.1 9.0 18.2 6.3 6.6 6.9 3.7 2 1 1 3 3 3 0 Putative ephrin-receptor like zf-met PF12874.7 EGE04059.1 - 1.4 9.4 19.9 1.9 9.0 0.4 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type RNA_POL_M_15KD PF02150.16 EGE04059.1 - 4.1 7.4 11.7 5.8 6.9 0.2 4.3 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit NCD3G PF07562.14 EGE04059.1 - 9.8 6.2 20.4 0.97 9.5 6.0 3.6 1 1 3 4 4 4 0 Nine Cysteines Domain of family 3 GPCR POT1 PF02765.17 EGE04060.1 - 2.7e-17 62.9 0.0 5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Aminotran_1_2 PF00155.21 EGE04061.1 - 1.2e-19 70.8 0.0 1.4e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EGE04061.1 - 0.00039 19.2 0.0 0.02 13.6 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III IF4E PF01652.18 EGE04063.1 - 3.9e-55 186.0 0.1 5.5e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 EGE04064.1 - 5.4e-32 111.4 0.3 1e-30 107.2 0.3 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SPC22 PF04573.12 EGE04065.1 - 1.1e-39 135.7 0.5 2.8e-37 127.8 0.5 2.1 1 1 0 1 1 1 1 Signal peptidase subunit Pmp3 PF01679.17 EGE04066.1 - 6.1e-19 68.0 8.2 7.9e-19 67.6 8.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BCDHK_Adom3 PF10436.9 EGE04067.1 - 2.6e-45 154.2 0.0 4.2e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase USP7_ICP0_bdg PF12436.8 EGE04068.1 - 5.5e-87 291.0 0.0 6.2e-86 287.6 0.0 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EGE04068.1 - 1.6e-71 240.3 0.9 6.5e-71 238.3 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EGE04068.1 - 1.6e-45 155.6 0.2 2.6e-45 154.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE04068.1 - 5.3e-21 75.5 0.0 1.2e-20 74.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EGE04068.1 - 1.2e-07 31.9 0.1 4.3e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.8 EGE04068.1 - 0.12 12.3 0.9 2.2 8.2 0.0 3.5 4 1 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.24 EGE04069.1 - 8.8e-47 159.4 0.2 1e-46 159.2 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 EGE04069.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 interleukin receptor mimic protein A CTD_bind PF04818.13 EGE04071.1 - 4e-11 43.6 0.0 9e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4614 PF15391.6 EGE04071.1 - 3.2 7.7 9.7 7.2 6.6 9.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4748 PF15932.5 EGE04075.1 - 4.8e-23 80.7 0.9 4.8e-23 80.7 0.9 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4748) ERCC3_RAD25_C PF16203.5 EGE04076.1 - 1.2e-122 407.9 0.7 2e-122 407.1 0.7 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGE04076.1 - 8.1e-34 116.5 0.0 3.3e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE04076.1 - 1.8e-14 54.1 0.0 4e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGE04076.1 - 7.3e-14 52.1 0.1 1.7e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGE04076.1 - 2.6e-07 29.7 0.0 3.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_34 PF13872.6 EGE04076.1 - 0.00093 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4677 PF15726.5 EGE04076.1 - 0.075 13.2 1.1 0.16 12.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Dynamin_N PF00350.23 EGE04077.1 - 2e-20 73.5 0.0 5e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGE04077.1 - 7.2e-14 51.7 0.0 2.8e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Dynamin central region FeoB_N PF02421.18 EGE04077.1 - 4.8e-05 22.9 0.4 0.031 13.8 0.1 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGE04077.1 - 0.00017 21.6 0.0 0.0015 18.6 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 EGE04077.1 - 0.013 15.6 0.6 0.05 13.8 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_23 PF13476.6 EGE04077.1 - 0.018 15.6 0.9 0.43 11.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EGE04077.1 - 0.024 14.4 1.2 0.27 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain EF-G-binding_N PF07299.11 EGE04077.1 - 0.083 13.4 0.2 0.36 11.4 0.2 2.2 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal TetR_C_16 PF17920.1 EGE04077.1 - 0.099 12.9 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Striatin PF08232.12 EGE04077.1 - 1.6 9.3 3.9 3 8.4 3.3 1.8 2 0 0 2 2 2 0 Striatin family MPM1 PF17234.2 EGE04078.1 - 0.084 13.1 4.3 0.18 12.0 4.3 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 G_path_suppress PF15991.5 EGE04078.1 - 1.2 9.2 11.2 0.43 10.7 7.2 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor NUDIX PF00293.28 EGE04079.1 - 1.4e-15 57.4 0.0 2.8e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EGE04079.1 - 6.5e-15 55.6 0.0 3e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EGE04079.1 - 2.2e-06 27.2 1.2 3.7e-06 26.5 1.2 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF5447 PF17525.2 EGE04079.1 - 0.013 15.9 1.2 37 4.9 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5447) Pkinase PF00069.25 EGE04080.1 - 2.5e-70 236.9 0.0 3.5e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04080.1 - 1.9e-32 112.6 0.0 3.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE04080.1 - 0.00035 20.0 0.5 0.00077 18.9 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE04080.1 - 0.0011 18.4 0.2 0.0054 16.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGE04080.1 - 0.031 13.0 0.0 0.031 13.0 0.0 2.6 4 0 0 4 4 4 0 Fungal protein kinase Haspin_kinase PF12330.8 EGE04080.1 - 0.071 12.0 0.1 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Questin_oxidase PF14027.6 EGE04081.1 - 3.6e-31 109.0 0.5 4.6e-31 108.6 0.5 1.1 1 0 0 1 1 1 1 Questin oxidase-like Thymidylate_kin PF02223.17 EGE04081.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 2 0 0 2 2 2 0 Thymidylate kinase GTP_cyclohydroI PF01227.22 EGE04083.1 - 6.2e-73 244.0 0.3 8.9e-73 243.5 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGE04083.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Cu_amine_oxidN2 PF02727.16 EGE04083.1 - 0.082 13.2 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain CAF1C_H4-bd PF12265.8 EGE04084.1 - 7.4e-30 103.0 0.8 5.6e-29 100.2 1.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGE04084.1 - 4.1e-28 97.1 8.2 3e-05 24.7 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04084.1 - 1.3e-06 28.5 1.2 0.14 12.5 0.1 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain XRN_M PF17846.1 EGE04085.1 - 2.5e-98 330.0 2.0 4.7e-98 329.0 2.0 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EGE04085.1 - 1.3e-97 326.0 0.0 2e-97 325.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EGE04085.1 - 1.1e-73 247.1 2.6 1.5e-73 246.7 0.1 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EGE04085.1 - 4.5e-33 113.3 0.0 1.1e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EGE04085.1 - 4.6e-23 81.1 0.1 1.2e-22 79.8 0.1 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EGE04085.1 - 1.2e-09 38.2 0.5 2.7e-09 37.0 0.5 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF2207 PF09972.9 EGE04085.1 - 0.084 11.6 0.7 0.15 10.8 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RXLR PF16810.5 EGE04085.1 - 0.64 10.5 2.4 1.3 9.4 2.4 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Cwf_Cwc_15 PF04889.12 EGE04085.1 - 2 8.1 7.8 3.8 7.2 7.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ACT_7 PF13840.6 EGE04086.1 - 1.4e-23 82.4 0.4 8.9e-16 57.4 0.1 2.5 2 1 0 2 2 2 2 ACT domain WD40 PF00400.32 EGE04087.1 - 9.3e-21 73.8 15.8 6.7e-05 23.6 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04087.1 - 1.7e-09 37.8 0.2 0.021 15.1 0.0 4.4 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EGE04087.1 - 4e-07 29.6 2.1 0.016 15.1 0.0 4.3 5 0 0 5 5 5 2 PQQ enzyme repeat Ge1_WD40 PF16529.5 EGE04087.1 - 0.021 13.8 1.1 0.93 8.4 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EGE04087.1 - 0.024 13.7 0.0 0.078 12.0 0.1 1.9 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain BBS2_Mid PF14783.6 EGE04087.1 - 0.11 12.5 0.0 0.96 9.5 0.0 2.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Septin PF00735.18 EGE04088.1 - 1.4e-112 375.6 0.3 2.1e-112 375.0 0.3 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGE04088.1 - 1.4e-07 31.6 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGE04088.1 - 4.9e-06 26.2 2.4 0.00016 21.2 0.1 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE04088.1 - 6.7e-06 26.1 1.1 5.7e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EGE04088.1 - 0.0021 18.3 0.6 0.0074 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EGE04088.1 - 0.0028 17.2 0.1 0.0052 16.3 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EGE04088.1 - 0.0059 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EGE04088.1 - 0.0059 15.9 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EGE04088.1 - 0.0085 15.2 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Casc1_N PF15927.5 EGE04088.1 - 0.012 15.3 10.5 0.032 13.9 10.5 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_24 PF13479.6 EGE04088.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGE04088.1 - 0.023 14.3 0.4 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 EGE04088.1 - 0.027 15.1 2.3 0.041 14.5 0.8 2.1 1 1 1 2 2 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 EGE04088.1 - 0.031 14.7 1.3 0.083 13.3 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EGE04088.1 - 0.037 13.3 0.0 0.046 13.0 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain T2SSE PF00437.20 EGE04088.1 - 0.042 12.9 0.4 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Ras PF00071.22 EGE04088.1 - 0.043 13.4 0.3 0.12 12.0 0.3 1.8 1 1 0 1 1 1 0 Ras family NACHT PF05729.12 EGE04088.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGE04088.1 - 0.06 13.9 0.1 0.3 11.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EGE04088.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EGE04088.1 - 0.15 11.8 0.4 5.4 6.8 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGE04088.1 - 0.26 11.0 0.7 14 5.4 0.1 2.6 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGE04088.1 - 0.36 10.9 5.4 6.1 6.9 0.0 3.2 2 1 1 3 3 3 0 Dynamin family DegS PF05384.11 EGE04088.1 - 4.1 6.9 12.4 2 7.9 7.4 2.6 2 1 1 3 3 3 0 Sensor protein DegS WD40 PF00400.32 EGE04089.1 - 3e-38 129.1 32.6 1.6e-09 38.2 0.9 12.9 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 EGE04089.1 - 1.8e-27 95.7 0.0 2.9e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGE04089.1 - 4e-22 78.3 0.0 0.0073 16.6 0.0 9.4 5 2 6 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE04089.1 - 2.8e-09 36.4 0.2 0.28 10.1 0.0 5.1 3 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGE04089.1 - 4.1e-07 30.1 0.9 0.0091 15.9 0.1 5.1 5 1 2 8 8 8 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGE04089.1 - 7.8e-07 28.1 1.8 0.63 8.6 0.0 4.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EGE04089.1 - 0.0018 17.0 0.1 0.031 12.9 0.0 2.7 3 1 1 4 4 4 1 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 EGE04089.1 - 0.0029 17.0 0.0 1.8 7.8 0.0 3.7 4 0 0 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 EGE04089.1 - 0.028 14.9 0.9 60 4.3 0.0 4.8 4 0 0 4 4 4 0 PQQ-like domain Pox_T4_N PF04491.12 EGE04089.1 - 0.046 13.6 0.4 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus SKIP_SNW PF02731.15 EGE04090.1 - 7.7e-72 240.2 5.7 7.7e-72 240.2 5.7 2.3 3 0 0 3 3 3 1 SKIP/SNW domain Nucleo_P87 PF07267.11 EGE04090.1 - 2.1 7.1 11.5 5.1 5.8 11.5 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Borrelia_P83 PF05262.11 EGE04090.1 - 2.7 6.4 14.4 5.7 5.3 14.4 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3395 PF11875.8 EGE04092.1 - 7.9e-32 110.3 0.1 1.7e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EGE04092.1 - 3.6e-16 59.0 0.1 8.2e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain KOG2701 PF09762.9 EGE04092.1 - 0.026 14.8 0.2 0.073 13.3 0.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) NAAA-beta PF15508.6 EGE04093.1 - 1.4e-11 44.5 0.1 2.9e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase BCS1_N PF08740.11 EGE04094.1 - 1.5e-40 139.2 2.6 3e-40 138.2 2.6 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGE04094.1 - 3e-17 63.3 0.0 3.9e-15 56.5 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE04094.1 - 0.0048 17.3 0.0 0.093 13.1 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGE04094.1 - 0.0085 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EGE04094.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EGE04094.1 - 0.094 12.7 0.0 0.39 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DSPc PF00782.20 EGE04095.1 - 5.9e-23 81.1 0.0 7.1e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE04095.1 - 0.0022 17.6 0.0 0.0079 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGE04095.1 - 0.029 14.7 0.0 0.043 14.1 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGE04095.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate SIS_2 PF13580.6 EGE04095.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 SIS domain DUF1877 PF08974.10 EGE04095.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Ribosomal_L4 PF00573.22 EGE04096.1 - 5.2e-36 124.1 0.2 7e-36 123.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGE04096.1 - 5.6e-30 103.2 1.2 9.4e-30 102.5 0.4 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Glyco_hydro_61 PF03443.14 EGE04098.1 - 4.7e-05 23.4 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UPF0029 PF01205.19 EGE04099.1 - 8.6e-36 122.5 0.0 1.4e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGE04099.1 - 0.00025 21.3 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain WD40 PF00400.32 EGE04100.1 - 3.5e-05 24.5 13.9 1.1 10.3 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Mito_carr PF00153.27 EGE04101.1 - 4.1e-56 186.9 2.0 3.7e-18 65.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGE04101.1 - 0.031 14.5 0.0 5.4 7.3 0.0 3.5 4 1 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF3278 PF11683.8 EGE04101.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Arteri_Gl PF00951.18 EGE04101.1 - 0.11 12.3 0.3 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein TadE PF07811.12 EGE04101.1 - 0.52 10.6 4.0 3.3 8.1 0.3 2.9 2 0 0 2 2 2 0 TadE-like protein EIIBC-GUT_N PF03612.14 EGE04102.1 - 0.19 11.5 3.5 0.32 10.7 3.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ras PF00071.22 EGE04103.1 - 1.2e-65 220.1 0.6 1.4e-65 219.8 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE04103.1 - 6.6e-36 123.2 0.2 1.2e-35 122.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE04103.1 - 1.6e-16 60.3 0.1 1.9e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE04103.1 - 2.2e-05 24.5 0.0 9.2e-05 22.5 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE04103.1 - 2.3e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGE04103.1 - 0.00015 21.4 0.4 0.00041 19.9 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGE04103.1 - 0.00023 20.6 0.1 0.0003 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EGE04103.1 - 0.00043 20.7 0.0 0.18 12.3 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EGE04103.1 - 0.00086 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGE04103.1 - 0.0042 16.6 0.1 0.023 14.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGE04103.1 - 0.0085 16.5 0.0 0.011 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGE04103.1 - 0.026 14.8 0.0 0.067 13.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EGE04103.1 - 0.033 13.5 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 EGE04103.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGE04103.1 - 0.064 13.8 0.1 0.15 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EGE04103.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EGE04103.1 - 0.072 13.1 0.1 0.2 11.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EGE04103.1 - 0.076 12.6 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGE04103.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGE04103.1 - 0.089 12.5 0.1 1.2 8.8 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ERAP1_C PF11838.8 EGE04104.1 - 6.5e-88 295.3 0.0 1.4e-87 294.2 0.0 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EGE04104.1 - 5e-84 281.2 5.2 7.8e-84 280.6 5.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGE04104.1 - 1.2e-39 136.4 0.1 6e-39 134.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain GlcNAc-1_reg PF18440.1 EGE04104.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Ssl1 PF04056.14 EGE04105.1 - 1.9e-73 246.4 0.0 2.6e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGE04105.1 - 3.4e-18 65.6 8.2 3.4e-18 65.6 8.2 2.4 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EGE04105.1 - 4.5e-15 56.2 0.0 1e-14 55.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 EGE04105.1 - 0.00062 19.4 3.5 0.00062 19.4 3.5 1.8 2 0 0 2 2 2 1 Transcription factor Tfb4 DZR PF12773.7 EGE04105.1 - 0.19 11.8 19.0 2.1 8.5 5.7 2.9 2 1 0 2 2 2 0 Double zinc ribbon YL1 PF05764.13 EGE04105.1 - 1.2 9.2 9.2 1.6 8.8 9.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein FYVE PF01363.21 EGE04105.1 - 4.6 7.5 18.8 0.027 14.6 5.4 2.6 2 0 0 2 2 2 0 FYVE zinc finger DUF4796 PF16044.5 EGE04105.1 - 9.7 5.7 14.4 1.2 8.7 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) DUF5572 PF17733.1 EGE04106.1 - 4.8e-25 87.1 0.2 9.8e-25 86.1 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PUF PF00806.19 EGE04107.1 - 1.7e-35 118.7 1.7 6.1e-06 25.6 0.0 8.4 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat RraB PF06877.11 EGE04107.1 - 0.0089 16.7 0.2 0.054 14.2 0.0 2.3 3 0 0 3 3 3 1 Regulator of ribonuclease activity B Peptidase_S9 PF00326.21 EGE04108.1 - 4.9e-08 32.7 1.0 9e-08 31.8 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGE04108.1 - 0.0013 18.4 0.2 0.0033 17.1 0.2 1.6 1 0 0 1 1 1 1 Putative esterase TPT PF03151.16 EGE04109.1 - 2.9e-58 197.5 17.0 3.5e-58 197.3 17.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PSII PF00421.19 EGE04109.1 - 6.9e-06 25.0 0.1 1.3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.20 EGE04109.1 - 3e-05 24.2 34.9 0.00066 19.9 12.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGE04109.1 - 0.082 12.1 21.1 1.5 7.9 21.1 2.1 1 1 0 1 1 1 0 UAA transporter family Molybdopterin PF00384.22 EGE04110.1 - 6.4e-71 239.6 0.0 7e-35 120.8 0.0 2.1 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EGE04110.1 - 2.9e-19 68.9 0.2 8.2e-19 67.4 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EGE04110.1 - 8.6e-19 68.0 0.0 2.1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EGE04110.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EGE04110.1 - 5.3e-08 32.7 0.6 5.3e-08 32.7 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EGE04110.1 - 0.12 12.2 1.1 3.5 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EGE04110.1 - 0.24 11.5 2.0 4.8 7.3 2.0 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster XRCC4 PF06632.12 EGE04111.1 - 2.1e-10 40.0 16.6 5.1e-10 38.7 16.6 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3585 PF12130.8 EGE04111.1 - 0.0091 16.1 3.7 0.0091 16.1 3.7 1.6 2 0 0 2 2 2 1 Bivalent Mical/EHBP Rab binding domain Baculo_gp64 PF03273.13 EGE04111.1 - 0.057 12.2 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family ISG65-75 PF11727.8 EGE04111.1 - 1.1 8.5 9.0 1.1 8.5 7.7 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF4407 PF14362.6 EGE04111.1 - 1.1 8.6 14.9 0.79 9.0 13.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 EGE04111.1 - 1.5 8.6 13.1 0.047 13.5 7.1 1.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Jnk-SapK_ap_N PF09744.9 EGE04111.1 - 2 8.6 10.8 0.23 11.7 5.2 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 V_ATPase_I PF01496.19 EGE04111.1 - 6.8 4.5 6.0 8.9 4.1 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Integrase_H2C2 PF17921.1 EGE04113.1 - 1.5e-07 31.4 0.8 1.5e-07 31.4 0.8 2.5 3 0 0 3 3 3 1 Integrase zinc binding domain ER_lumen_recept PF00810.18 EGE04114.1 - 1.7e-54 184.6 7.0 2.8e-54 184.0 7.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.12 EGE04114.1 - 1 9.3 7.5 0.19 11.7 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF485 PQ-loop PF04193.14 EGE04114.1 - 1.3 8.8 15.9 0.73 9.7 0.2 4.4 4 1 1 5 5 5 0 PQ loop repeat DUF382 PF04037.13 EGE04116.1 - 3.2e-59 198.6 1.6 3.2e-59 198.6 1.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EGE04116.1 - 2.4e-20 72.1 3.7 5.5e-20 71.0 3.7 1.6 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.11 EGE04117.1 - 2.1e-21 76.0 0.1 2.5e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 EGE04118.1 - 5.1e-14 52.8 0.1 4.2e-13 49.8 0.0 2.6 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGE04118.1 - 2.5e-11 43.8 0.0 5.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EGE04118.1 - 0.16 12.7 0.1 0.16 12.7 0.1 2.3 2 0 0 2 2 2 0 Double-stranded RNA binding motif PLAC9 PF15205.6 EGE04118.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 Pannexin_like PF12534.8 EGE04118.1 - 0.23 10.5 3.8 0.37 9.8 3.8 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 RTA1 PF04479.13 EGE04119.1 - 2.8e-55 187.2 3.0 3.5e-55 186.8 3.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 EGE04120.1 - 2.7e-08 33.8 10.3 4.4e-08 33.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE04120.1 - 1e-07 31.1 0.0 1.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 EGE04121.1 - 4.2e-23 82.3 0.0 1.7e-21 77.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE04121.1 - 6.5e-15 56.3 0.0 9.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE04121.1 - 1.8e-11 43.8 0.0 4.3e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGE04121.1 - 8.8e-07 28.9 0.1 0.00023 20.9 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EGE04121.1 - 9.4e-06 25.9 0.0 1.6e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EGE04121.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 EGE04121.1 - 0.0048 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 EGE04121.1 - 0.0048 16.6 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EGE04121.1 - 0.0054 15.7 0.0 0.0099 14.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EGE04121.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGE04121.1 - 0.012 15.0 0.0 0.59 9.4 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 EGE04121.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 EGE04121.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 EGE04121.1 - 0.065 12.8 0.1 0.53 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) Abhydro_lipase PF04083.16 EGE04121.1 - 0.17 11.5 0.1 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S3Ae PF01015.18 EGE04122.1 - 1.4e-84 282.7 5.0 1.7e-84 282.4 5.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EGE04122.1 - 0.017 15.7 0.4 0.096 13.2 0.2 2.2 1 1 1 2 2 2 0 Translation initiation factor SUI1 LPD1 PF18796.1 EGE04122.1 - 0.15 12.2 0.1 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 1 GTP_CH_N PF12471.8 EGE04123.1 - 4.4e-91 303.9 0.0 6.4e-91 303.4 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EGE04123.1 - 5.6e-16 58.6 0.0 9.1e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.13 EGE04124.1 - 3e-28 97.7 0.6 3.6e-28 97.4 0.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Peptidase_U32 PF01136.19 EGE04124.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Peptidase family U32 zf-Sec23_Sec24 PF04810.15 EGE04124.1 - 0.52 10.4 3.9 13 5.9 1.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger UPRTase PF14681.6 EGE04125.1 - 9.3e-79 263.7 0.0 1.2e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGE04125.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain WAPL PF07814.13 EGE04126.1 - 3.5e-79 266.2 2.6 5.1e-79 265.7 2.6 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ric8 PF10165.9 EGE04126.1 - 0.018 14.1 0.4 0.03 13.4 0.4 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn RIX1 PF08167.12 EGE04126.1 - 0.033 13.9 0.4 0.27 10.9 0.2 2.3 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Ras PF00071.22 EGE04130.1 - 4.3e-47 159.7 0.2 4.9e-47 159.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE04130.1 - 5.2e-17 62.2 0.1 7.5e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE04130.1 - 3.5e-07 29.8 0.0 3.8e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE04130.1 - 1.4e-05 24.8 0.2 0.00027 20.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGE04130.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE04130.1 - 0.0011 18.9 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGE04130.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGE04130.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3568 PF12092.8 EGE04130.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) AAA_14 PF13173.6 EGE04130.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EGE04130.1 - 0.14 11.7 0.1 0.43 10.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.25 EGE04131.1 - 2.4e-34 118.9 0.0 4.3e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGE04131.1 - 6.7e-20 71.3 4.8 6.7e-20 71.3 4.8 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain CAMSAP_CC1 PF17095.5 EGE04131.1 - 0.03 14.2 2.7 0.068 13.0 2.7 1.5 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin DUF3698 PF12479.8 EGE04131.1 - 0.074 13.6 0.2 0.37 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) DUF4337 PF14235.6 EGE04131.1 - 2 8.5 4.8 3.5 7.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-Hacid_dh_C PF02826.19 EGE04132.1 - 8.9e-49 165.2 0.0 1.4e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE04132.1 - 2.2e-34 118.0 0.0 3.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EGE04132.1 - 7.4e-05 22.4 0.2 0.00021 21.0 0.1 1.8 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 EGE04132.1 - 0.00012 22.3 0.3 0.00033 20.9 0.3 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGE04132.1 - 0.0081 16.2 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EGE04132.1 - 0.014 15.0 0.1 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EGE04132.1 - 0.016 15.7 0.1 0.06 13.9 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain DUF1780 PF08682.10 EGE04132.1 - 0.045 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) 3HCDH_N PF02737.18 EGE04132.1 - 0.19 11.6 1.7 3.2 7.6 0.6 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UPF0242 PF06785.11 EGE04133.1 - 0.0092 16.1 4.9 0.0098 16.0 4.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1489 PF07370.11 EGE04133.1 - 0.022 14.5 0.5 0.032 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) PMSI1 PF15322.6 EGE04133.1 - 0.029 13.8 1.1 0.035 13.6 1.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF2681 PF10883.8 EGE04133.1 - 0.041 14.3 0.7 0.041 14.3 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) BBP1_C PF15272.6 EGE04133.1 - 0.044 13.6 4.7 0.054 13.3 4.7 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ATP-synt_E PF05680.12 EGE04133.1 - 0.11 12.8 0.6 0.11 12.8 0.6 2.1 2 0 0 2 2 2 0 ATP synthase E chain FUSC PF04632.12 EGE04133.1 - 4.6 5.6 7.4 5.8 5.3 7.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vpu PF00558.19 EGE04133.1 - 8.6 6.2 9.2 0.3 10.9 0.3 2.5 1 1 2 3 3 3 0 Vpu protein Pkinase PF00069.25 EGE04134.1 - 2.2e-36 125.6 0.0 6.3e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04134.1 - 2.1e-10 40.3 0.0 2.3e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Peptidase_S64 PF08192.11 EGE04135.1 - 6.4e-08 31.6 0.7 1e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S7 PF00949.21 EGE04135.1 - 2e-05 24.4 0.0 0.0011 18.8 0.0 2.7 2 0 0 2 2 2 1 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.6 EGE04135.1 - 3.9e-05 24.6 0.0 0.00018 22.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 EGE04135.1 - 0.0023 17.2 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 DUF31 PF01732.16 EGE04135.1 - 0.014 14.9 0.4 0.2 11.1 0.1 2.2 2 0 0 2 2 2 0 Putative peptidase (DUF31) ANAPC15 PF15243.6 EGE04135.1 - 0.077 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 G_glu_transpept PF01019.21 EGE04136.1 - 2.6e-124 415.8 0.0 3.4e-124 415.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase P5-ATPase PF12409.8 EGE04137.1 - 1.7e-40 138.0 0.0 3.6e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EGE04137.1 - 3.1e-30 105.1 1.1 4.8e-30 104.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGE04137.1 - 1.6e-14 54.7 0.0 3.4e-08 34.0 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE04137.1 - 0.00049 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGE04137.1 - 0.00056 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGE04137.1 - 0.0077 16.0 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NAP PF00956.18 EGE04138.1 - 1.9e-98 328.9 7.4 1.9e-98 328.9 7.4 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Nop14 PF04147.12 EGE04138.1 - 4.9 5.2 33.7 0.78 7.9 24.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.9 EGE04138.1 - 5.2 6.1 36.0 1.8 7.6 25.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myosin_head PF00063.21 EGE04139.1 - 1.3e-195 651.5 3.5 1.2e-131 440.2 2.0 3.2 3 0 0 3 3 3 3 Myosin head (motor domain) DIL PF01843.19 EGE04139.1 - 2.9e-26 91.7 2.6 2.9e-26 91.7 2.6 3.3 3 1 1 4 4 4 1 DIL domain IQ PF00612.27 EGE04139.1 - 6.5e-12 44.1 31.9 3.5e-05 23.2 0.6 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif GAS PF13851.6 EGE04139.1 - 0.00087 18.7 15.0 0.00087 18.7 15.0 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGE04139.1 - 0.0028 16.6 20.5 0.0039 16.1 19.1 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein Myosin_N PF02736.19 EGE04139.1 - 0.003 17.4 3.3 0.0076 16.1 3.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EGE04139.1 - 0.0073 16.7 0.0 0.031 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain EzrA PF06160.12 EGE04139.1 - 0.049 11.8 15.9 1.4 7.0 15.1 2.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_22 PF13401.6 EGE04139.1 - 0.065 13.5 5.0 0.072 13.4 0.2 3.4 2 1 0 2 2 2 0 AAA domain CALCOCO1 PF07888.11 EGE04139.1 - 0.23 10.3 22.0 0.098 11.5 19.6 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 EGE04139.1 - 0.34 11.4 19.6 1.8 9.0 19.6 2.2 1 1 0 1 1 1 0 Fez1 KASH_CCD PF14662.6 EGE04139.1 - 0.76 9.6 23.8 0.28 11.0 19.2 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Baculo_PEP_C PF04513.12 EGE04139.1 - 1.5 8.9 11.5 0.42 10.6 5.6 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EGE04139.1 - 1.5 9.3 11.0 1.2 9.6 0.1 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EGE04139.1 - 3.6 7.6 26.8 0.071 13.2 3.3 3.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Ham1p_like PF01725.16 EGE04140.1 - 6.8e-57 192.4 0.0 7.7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EGE04141.1 - 2.8e-26 92.6 0.1 5.2e-26 91.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGE04141.1 - 4.1e-08 33.7 0.0 1.1e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGE04141.1 - 0.00035 21.0 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE04141.1 - 0.0018 18.7 0.2 0.014 15.7 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EGE04141.1 - 0.0019 18.5 0.6 0.0032 17.7 0.6 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE04141.1 - 0.0019 18.3 0.1 0.033 14.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE04141.1 - 0.0024 18.1 0.0 0.0051 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGE04141.1 - 0.0029 17.6 0.0 0.0075 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 EGE04141.1 - 0.0043 17.2 0.1 0.018 15.2 0.0 1.9 1 1 1 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 EGE04141.1 - 0.0055 16.6 0.1 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 NTPase KTI12 PF08433.10 EGE04141.1 - 0.0067 15.9 0.0 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 EGE04141.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 EGE04141.1 - 0.038 14.4 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 EGE04141.1 - 0.13 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EGE04141.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGE04141.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EGE04141.1 - 0.21 11.9 0.3 0.4 11.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain Peptidase_C78 PF07910.13 EGE04142.1 - 8.8e-66 221.4 0.0 1.2e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 EGE04142.1 - 0.00084 19.6 3.2 0.072 13.4 1.0 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 EGE04142.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 EGE04142.1 - 0.19 11.5 0.5 0.43 10.4 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EGE04142.1 - 1.1 10.3 3.7 6 8.0 1.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger AA_kinase PF00696.28 EGE04144.1 - 2.3e-42 145.3 0.1 3.7e-42 144.6 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EGE04144.1 - 2.7e-14 52.7 1.5 1.5e-11 43.9 0.2 2.6 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EGE04144.1 - 1.1e-12 47.4 0.1 5.2e-09 35.7 0.1 2.9 3 0 0 3 3 3 2 ACT domain zf-Tim10_DDP PF02953.15 EGE04145.1 - 2.1e-18 65.7 2.0 2.7e-18 65.3 2.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.17 EGE04146.1 - 6.4e-49 165.5 3.3 1e-48 164.8 3.3 1.3 1 1 0 1 1 1 1 G10 protein DUF1257 PF06868.11 EGE04146.1 - 0.11 12.8 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Forkhead PF00250.18 EGE04147.1 - 8.8e-34 115.6 0.0 1.5e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Ribosomal_L23eN PF03939.13 EGE04148.1 - 5e-27 93.9 8.8 5e-27 93.9 8.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGE04148.1 - 4.3e-13 49.4 3.9 5.4e-13 49.1 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 Linker_histone PF00538.19 EGE04148.1 - 0.43 11.0 3.2 0.34 11.3 0.3 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family Bmt2 PF11968.8 EGE04149.1 - 1.5e-86 289.8 0.0 1.8e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EGE04149.1 - 0.033 14.0 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain eRF1_2 PF03464.15 EGE04151.1 - 1.6e-46 158.0 0.0 2.5e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGE04151.1 - 4.5e-39 133.4 0.2 1.1e-38 132.1 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGE04151.1 - 2.1e-19 69.8 0.0 3.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGE04151.1 - 5.1e-10 39.8 0.0 9.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGE04151.1 - 1.1e-08 35.4 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 EGE04152.1 - 4.5e-58 196.1 0.0 6e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EGE04152.1 - 6.7e-06 25.8 0.0 2.5e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.19 EGE04153.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Abhydrolase_3 PF07859.13 EGE04154.1 - 1.6e-44 152.3 0.0 8e-43 146.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGE04154.1 - 1.8e-07 30.4 0.3 1.4e-06 27.5 0.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EGE04154.1 - 0.13 11.7 0.1 2.5 7.5 0.1 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DER1 PF04511.15 EGE04155.1 - 6.2e-26 91.5 3.7 7.2e-26 91.3 3.7 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EGE04155.1 - 0.84 9.6 11.3 0.075 13.0 5.9 1.8 2 0 0 2 2 2 0 Rhomboid family DKCLD PF08068.12 EGE04156.1 - 8.4e-34 115.4 0.2 2.5e-32 110.7 0.3 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EGE04156.1 - 3.7e-23 81.5 1.5 6.8e-23 80.6 1.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGE04156.1 - 5.5e-23 82.0 0.2 5.6e-20 72.2 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGE04156.1 - 1.9e-12 47.0 0.7 4e-12 45.9 0.7 1.5 1 0 0 1 1 1 1 PUA domain DUF4407 PF14362.6 EGE04156.1 - 0.62 9.4 10.0 1.1 8.6 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 EGE04156.1 - 0.74 8.5 4.7 0.9 8.2 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLTH PF10607.9 EGE04157.1 - 1.1e-35 122.7 0.5 1.9e-35 121.9 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain INCA1 PF15142.6 EGE04157.1 - 0.061 13.3 0.4 0.13 12.3 0.2 1.6 2 0 0 2 2 2 0 INCA1 DUF5398 PF17376.2 EGE04157.1 - 0.062 13.9 0.6 4.8 7.9 0.0 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5398) SKA2 PF16740.5 EGE04157.1 - 0.47 10.3 3.7 0.26 11.1 0.5 2.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Adaptin_binding PF10199.9 EGE04157.1 - 0.54 10.9 2.4 0.35 11.5 0.3 1.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 GIT_CC PF16559.5 EGE04157.1 - 3.8 7.4 5.4 10 6.1 0.9 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2431 PF10354.9 EGE04158.1 - 1.1e-44 152.7 0.0 1.8e-44 152.0 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) EamA PF00892.20 EGE04159.1 - 1.9e-05 24.8 6.7 1.9e-05 24.8 6.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Dscam_C PF12355.8 EGE04159.1 - 0.66 10.9 4.5 0.16 12.9 1.2 1.6 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Methyltr_RsmB-F PF01189.17 EGE04160.1 - 1.6e-73 246.6 0.0 2.6e-73 246.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGE04160.1 - 6.2e-08 33.0 0.0 3.9e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGE04160.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4717 PF15838.5 EGE04160.1 - 0.29 11.2 3.8 0.86 9.7 3.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Blt1 PF12754.7 EGE04161.1 - 2.2e-53 180.6 0.9 2.7e-53 180.3 0.9 1.0 1 0 0 1 1 1 1 Blt1 N-terminal domain DUF2340 PF10209.9 EGE04161.1 - 0.0055 17.2 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Striatin PF08232.12 EGE04162.1 - 8e-47 159.7 3.6 8e-47 159.7 3.6 2.6 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 EGE04162.1 - 1.5e-25 89.0 22.3 2.4e-05 25.0 0.4 8.0 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04162.1 - 0.00013 22.2 0.0 5.2 7.4 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE04162.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGE04162.1 - 0.14 10.7 0.0 0.31 9.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain XPA_C PF05181.12 EGE04163.1 - 2.8e-26 91.2 2.3 5.6e-26 90.3 2.3 1.6 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.6 EGE04163.1 - 0.0066 16.4 3.3 0.89 9.6 0.2 2.8 2 0 0 2 2 2 2 YhfH-like protein ADD_DNMT3 PF17980.1 EGE04163.1 - 0.28 11.2 3.3 0.12 12.4 0.5 1.7 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Ribosomal_L32e PF01655.18 EGE04163.1 - 0.34 11.3 2.2 0.46 10.9 0.5 2.0 2 0 0 2 2 2 0 Ribosomal protein L32 MAS20 PF02064.15 EGE04163.1 - 2.5 8.2 5.8 0.59 10.2 1.7 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor PIG-P PF08510.12 EGE04164.1 - 3e-53 178.8 0.9 3e-53 178.8 0.9 1.7 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 EGE04164.1 - 0.012 15.9 7.8 0.021 15.1 7.8 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) BUD22 PF09073.10 EGE04164.1 - 0.056 12.8 5.3 0.071 12.4 5.3 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGE04164.1 - 0.11 10.8 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGE04164.1 - 0.14 11.6 3.4 0.18 11.2 3.4 1.1 1 0 0 1 1 1 0 SDA1 Phage_holin_3_6 PF07332.11 EGE04164.1 - 0.29 11.2 0.1 0.45 10.6 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HsbA PF12296.8 EGE04165.1 - 5.7e-29 101.0 7.8 5.7e-29 101.0 6.4 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A MF_alpha_N PF05436.11 EGE04165.1 - 0.046 13.6 1.7 0.083 12.8 0.5 2.1 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF3216 PF11505.8 EGE04165.1 - 0.096 12.9 0.1 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Abhydrolase_1 PF00561.20 EGE04167.1 - 6.9e-11 42.3 3.1 7.1e-10 39.0 3.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE04167.1 - 4.7e-09 37.2 0.9 6.1e-09 36.8 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE04167.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 UCH PF00443.29 EGE04169.1 - 1.2e-10 41.3 0.0 2.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 EGE04169.1 - 3.1e-10 39.8 11.8 5.2e-10 39.0 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.20 EGE04169.1 - 4e-06 26.4 23.4 0.024 14.5 4.8 4.6 4 0 0 4 4 4 3 MORN repeat Prok-RING_4 PF14447.6 EGE04169.1 - 0.0094 15.8 10.6 0.019 14.8 10.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 USP7_ICP0_bdg PF12436.8 EGE04169.1 - 0.1 11.9 0.0 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 zf-RING_5 PF14634.6 EGE04169.1 - 0.59 10.1 12.4 1.1 9.2 12.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 EGE04171.1 - 1.7e-129 431.2 0.0 2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 EGE04173.1 - 8.9e-17 61.0 0.0 8.5e-09 35.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE04173.1 - 4.9e-06 26.7 0.0 0.044 14.0 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGE04173.1 - 4.5e-05 23.3 4.4 0.00029 20.7 0.0 3.5 3 0 0 3 3 3 1 Myb DNA-binding like NmrA PF05368.13 EGE04176.1 - 5e-56 189.9 0.1 6.5e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE04176.1 - 1.2e-18 67.6 0.0 1.8e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGE04176.1 - 1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AIG1 PF04548.16 EGE04176.1 - 0.051 12.9 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 AIG1 family Epimerase PF01370.21 EGE04176.1 - 0.055 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGE04176.1 - 0.12 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CorA PF01544.18 EGE04177.1 - 5.1e-09 35.9 0.4 1.1e-08 34.8 0.4 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CNF1 PF05785.12 EGE04177.1 - 0.033 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor FtsX PF02687.21 EGE04177.1 - 0.27 11.7 1.2 0.49 10.9 1.2 1.3 1 0 0 1 1 1 0 FtsX-like permease family Gcd10p PF04189.13 EGE04181.1 - 1.9e-81 273.4 0.0 2.8e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family AroM PF07302.11 EGE04181.1 - 0.12 11.7 0.0 0.54 9.6 0.0 2.0 1 1 0 1 1 1 0 AroM protein MINDY_DUB PF04424.13 EGE04182.1 - 2.7e-19 69.3 0.0 4.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Patatin PF01734.22 EGE04185.1 - 2.2e-07 31.3 0.0 3.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase APH PF01636.23 EGE04186.1 - 5e-10 39.7 0.0 8.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE04186.1 - 0.0096 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGE04186.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF87 PF01935.17 EGE04190.1 - 0.0013 18.9 0.0 0.0038 17.4 0.0 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EGE04190.1 - 0.008 15.6 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EGE04190.1 - 0.033 14.4 0.0 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGE04190.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGE04190.1 - 0.16 12.3 0.0 0.75 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain Ribonuclease_3 PF00636.26 EGE04191.1 - 0.0011 19.5 0.0 0.0079 16.8 0.0 2.5 3 1 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGE04191.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease-III-like VPS11_C PF12451.8 EGE04191.1 - 0.14 12.4 0.2 0.43 10.8 0.2 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Dynamin_N PF00350.23 EGE04192.1 - 8.4e-18 65.0 0.0 1.6e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGE04192.1 - 7.4e-17 61.5 0.0 1.5e-16 60.5 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region RNase_H PF00075.24 EGE04193.1 - 3.8e-08 33.6 0.0 1.5e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 RNase H HBS1_N PF08938.10 EGE04195.1 - 0.061 13.6 0.3 0.091 13.1 0.3 1.3 1 0 0 1 1 1 0 HBS1 N-terminus DUF812 PF05667.11 EGE04196.1 - 0.29 10.0 0.0 0.41 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pkinase PF00069.25 EGE04198.1 - 1.3e-32 113.2 0.0 3.1e-32 112.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04198.1 - 1.1e-10 41.3 0.0 4.2e-09 36.1 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Arylsulfotran_2 PF14269.6 EGE04199.1 - 1.6e-111 372.5 0.4 2.3e-111 372.0 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EGE04199.1 - 6.3e-16 58.3 0.1 2e-14 53.3 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) RasGEF PF00617.19 EGE04200.1 - 1.6e-60 204.3 0.1 2.8e-60 203.6 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGE04200.1 - 7.1e-26 90.5 0.1 1.6e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EGE04200.1 - 7.8e-13 47.8 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGE04200.1 - 8.2e-11 41.4 0.1 2.1e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGE04200.1 - 9.6e-11 41.4 0.1 2.1e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EGE04200.1 - 0.018 15.1 1.7 0.021 14.9 0.0 2.1 2 0 0 2 2 2 0 WW domain RHH_1 PF01402.21 EGE04200.1 - 0.058 13.4 0.7 0.21 11.6 0.7 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family CDC45 PF02724.14 EGE04201.1 - 5.8 5.1 6.6 6.3 5.0 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.18 EGE04202.1 - 2.2e-19 69.5 3.3 4.6e-19 68.5 3.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EGE04202.1 - 4.7e-07 29.9 13.8 8e-05 22.9 5.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain Mucin PF01456.17 EGE04202.1 - 0.0048 16.9 14.9 0.015 15.3 14.9 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein zf-C2H2 PF00096.26 EGE04202.1 - 0.016 15.6 18.3 0.28 11.7 7.6 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EGE04202.1 - 1.1 10.0 5.3 2 9.1 0.0 2.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats UPRTase PF14681.6 EGE04204.1 - 2.6e-70 236.1 0.0 3e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGE04204.1 - 9.3e-07 28.5 0.0 1.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain CRCB PF02537.15 EGE04205.1 - 1.1e-39 134.6 12.2 2.2e-23 82.4 5.7 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Prion_bPrPp PF11587.8 EGE04205.1 - 3.7 7.5 6.0 2.5 8.0 1.7 2.5 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal DUF4234 PF14018.6 EGE04206.1 - 0.024 14.7 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) PAP_PilO PF06864.12 EGE04206.1 - 0.087 11.6 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF1418 PF07214.12 EGE04206.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) JAB PF01398.21 EGE04207.1 - 2.1e-29 101.9 0.0 3.8e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGE04207.1 - 1.2e-24 87.0 0.0 2.3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGE04207.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain SRP1_TIP1 PF00660.17 EGE04207.1 - 0.096 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family Pkinase PF00069.25 EGE04208.1 - 3.6e-22 79.0 0.0 4.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04208.1 - 1.9e-17 63.4 0.0 3.7e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE04208.1 - 0.00016 21.1 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGE04208.1 - 0.024 14.2 0.0 0.063 12.9 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase MAP65_ASE1 PF03999.12 EGE04209.1 - 4.3e-69 233.8 38.8 5.8e-68 230.1 33.2 2.8 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Seryl_tRNA_N PF02403.22 EGE04209.1 - 0.093 13.0 13.2 5.2 7.3 0.1 4.6 5 0 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF5101 PF17031.5 EGE04209.1 - 0.8 9.8 3.8 0.34 11.0 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) RmuC PF02646.16 EGE04209.1 - 1.2 8.3 6.1 7.9 5.5 0.2 2.9 3 0 0 3 3 3 0 RmuC family Occludin_ELL PF07303.13 EGE04209.1 - 1.4 9.7 5.2 3.4 8.4 0.1 3.6 2 2 0 2 2 2 0 Occludin homology domain CC2-LZ PF16516.5 EGE04209.1 - 1.4 9.3 15.1 2.4 8.6 1.6 4.0 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spectrin PF00435.21 EGE04209.1 - 2 8.9 12.5 0.45 11.0 0.7 3.9 3 1 1 4 4 4 0 Spectrin repeat TMF_TATA_bd PF12325.8 EGE04209.1 - 2.2 8.5 21.4 0.19 11.9 2.2 4.1 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding tRNA-synt_1c PF00749.21 EGE04210.1 - 1.1e-92 310.3 0.0 1.9e-92 309.5 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 EGE04211.1 - 8e-39 133.1 0.5 1.4e-38 132.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGE04211.1 - 6.3e-24 83.9 5.4 1.1e-23 83.2 5.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGE04211.1 - 3.8e-13 49.6 19.2 6.8e-13 48.8 19.2 1.4 1 0 0 1 1 1 1 DnaJ central domain PHD_4 PF16866.5 EGE04211.1 - 9.8 6.3 8.4 0.67 10.1 0.7 2.7 2 1 1 3 3 3 0 PHD-finger 4HBT PF03061.22 EGE04212.1 - 1.2e-07 31.9 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EGE04212.1 - 0.00021 20.7 0.2 0.0003 20.2 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 EGE04212.1 - 0.0012 19.3 0.0 0.0016 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.22 EGE04213.1 - 1.3e-24 87.1 0.0 2e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EGE04213.1 - 0.073 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 S4 domain Glyco_tran_WecB PF03808.13 EGE04213.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Ribosomal_L32e PF01655.18 EGE04214.1 - 9.5e-49 164.3 0.5 9.5e-49 164.3 0.5 1.4 1 1 1 2 2 2 1 Ribosomal protein L32 Sec2p PF06428.11 EGE04215.1 - 3.6e-10 39.7 13.7 3.6e-10 39.7 13.7 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EGE04215.1 - 0.0047 17.2 33.1 0.0087 16.3 13.8 2.1 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF4795 PF16043.5 EGE04215.1 - 0.054 13.1 7.8 0.11 12.1 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EGE04215.1 - 0.079 13.6 1.3 0.079 13.6 1.3 3.5 3 1 0 3 3 3 0 SlyX DUF2072 PF09845.9 EGE04215.1 - 0.17 12.1 5.6 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF4407 PF14362.6 EGE04215.1 - 1.3 8.3 16.8 0.34 10.2 1.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EGE04215.1 - 6.1 5.6 18.9 0.58 9.0 8.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein RRM_1 PF00076.22 EGE04216.1 - 3.2e-15 55.7 0.0 7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XH PF03469.14 EGE04217.1 - 0.037 13.9 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 XH domain 2-Hacid_dh_C PF02826.19 EGE04218.1 - 2.3e-55 186.7 0.0 3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE04218.1 - 1.2e-17 63.9 0.0 1.5e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGE04218.1 - 7.3e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EGE04218.1 - 0.0011 19.8 0.0 0.0049 17.7 0.0 2.1 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EGE04218.1 - 0.006 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent zf-C2HE PF16278.5 EGE04219.1 - 3.9e-21 75.3 0.7 3.9e-21 75.3 0.7 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EGE04219.1 - 6.5e-16 58.8 0.1 1.5e-07 31.9 0.1 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGE04219.1 - 1.3e-12 48.3 1.4 4.3e-12 46.6 1.4 1.8 1 1 0 1 1 1 1 HIT domain Cyclin_N PF00134.23 EGE04220.1 - 8.3e-45 151.6 0.4 1.6e-44 150.7 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGE04220.1 - 1.2e-34 118.9 0.7 7.1e-34 116.5 0.0 2.5 3 0 0 3 3 3 1 Cyclin, C-terminal domain Zn_clus PF00172.18 EGE04223.1 - 0.00079 19.5 12.6 0.0017 18.5 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4349 PF14257.6 EGE04223.1 - 0.023 14.1 0.1 0.023 14.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CHZ PF09649.10 EGE04223.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.3 3 0 0 3 3 3 0 Histone chaperone domain CHZ Pkinase PF00069.25 EGE04224.1 - 8.3e-05 22.1 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04224.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 EGE04224.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_Rpc4 PF05132.14 EGE04225.1 - 5.3e-33 114.5 0.1 5.3e-33 114.5 0.1 3.4 1 1 1 2 2 2 1 RNA polymerase III RPC4 KRE1 PF17056.5 EGE04226.1 - 1.6e-06 27.7 0.1 3.3e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 Killer toxin-resistance protein 1 Fmp27 PF10344.9 EGE04227.1 - 1.1e-170 569.7 0.0 2.2e-170 568.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EGE04227.1 - 2.8e-159 531.0 0.2 9.8e-121 403.9 0.0 3.9 3 1 2 5 5 5 2 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EGE04227.1 - 7.4e-151 503.3 6.4 1.2e-150 502.6 6.4 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EGE04227.1 - 1.5e-55 187.6 0.1 4.2e-55 186.1 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EGE04227.1 - 1.2e-51 174.7 0.0 3.4e-51 173.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EGE04227.1 - 9.8e-28 96.9 0.0 6.5e-27 94.3 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.13 EGE04227.1 - 0.25 11.2 1.3 4.1 7.3 0.0 3.0 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ MTABC_N PF16185.5 EGE04228.1 - 0.022 14.2 1.2 0.035 13.6 1.2 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region B-block_TFIIIC PF04182.12 EGE04229.1 - 2.6e-21 75.6 0.1 5.7e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 EGE04229.1 - 0.075 12.9 0.1 0.075 12.9 0.1 3.0 3 0 0 3 3 3 0 MarR family HTH_36 PF13730.6 EGE04229.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UQ_con PF00179.26 EGE04230.1 - 7.2e-19 67.8 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGE04230.1 - 0.019 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 RWD domain DHHC PF01529.20 EGE04231.1 - 2.8e-36 124.6 12.9 2.8e-36 124.6 12.9 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.22 EGE04234.1 - 3.3e-33 114.8 7.8 3.3e-33 114.8 7.8 1.8 2 0 0 2 2 2 1 Rhomboid family DUF2177 PF09945.9 EGE04234.1 - 0.34 11.0 6.1 0.43 10.7 0.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) DUF4381 PF14316.6 EGE04234.1 - 8.3 6.6 6.7 1.6 9.0 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) GST_C_2 PF13410.6 EGE04235.1 - 3.3e-05 23.8 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE04235.1 - 0.095 12.9 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Kinetochor_Ybp2 PF08568.10 EGE04237.1 - 1.8e-117 393.5 0.2 2.1e-117 393.2 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SPT_ssu-like PF11779.8 EGE04238.1 - 0.0042 16.7 3.0 0.0059 16.2 3.0 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like PLDc_2 PF13091.6 EGE04240.1 - 8.6e-13 48.3 0.2 2.6e-07 30.6 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EGE04240.1 - 9.2e-05 22.5 0.1 0.00023 21.2 0.1 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EGE04240.1 - 0.14 11.4 0.1 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DUF883 PF05957.13 EGE04240.1 - 6.6 7.4 5.6 1.6 9.4 0.9 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4834 PF16118.5 EGE04240.1 - 7.9 7.5 6.9 36 5.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GFA PF04828.14 EGE04241.1 - 5.5e-20 71.5 0.3 8.5e-20 70.9 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cyanate_lyase PF02560.14 EGE04242.1 - 5.4e-33 112.7 0.0 1.1e-32 111.7 0.0 1.5 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EGE04242.1 - 0.00017 21.9 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EGE04242.1 - 0.00077 19.9 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.22 EGE04242.1 - 0.018 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r1_1 PF03979.14 EGE04242.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Myb_DNA-binding PF00249.31 EGE04242.1 - 0.16 12.2 0.0 52 4.1 0.0 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 EGE04243.1 - 2.1e-10 40.5 23.4 0.19 12.7 0.2 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE04243.1 - 7.6e-07 29.2 24.5 0.079 13.5 0.1 6.0 7 0 0 7 7 6 3 Zinc finger, C2H2 type zf-met PF12874.7 EGE04243.1 - 3.1e-05 24.2 15.3 0.033 14.6 0.2 4.9 5 0 0 5 5 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGE04243.1 - 0.00015 21.9 0.9 0.019 15.3 0.1 4.6 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EGE04243.1 - 0.0075 16.9 7.9 0.032 14.9 0.6 3.0 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats Prok-RING_4 PF14447.6 EGE04243.1 - 0.051 13.4 3.2 3 7.8 1.7 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CSL PF05207.13 EGE04243.1 - 0.12 12.1 7.8 0.29 10.9 0.2 2.7 2 1 0 2 2 2 0 CSL zinc finger FOXP-CC PF16159.5 EGE04243.1 - 0.78 10.4 11.7 2 9.1 0.3 3.9 3 2 1 4 4 4 0 FOXP coiled-coil domain zf-C3HC4_2 PF13923.6 EGE04243.1 - 0.88 9.5 8.5 4.4 7.2 0.9 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 EGE04243.1 - 1 9.7 22.0 3.4 8.1 2.8 5.1 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 EGE04243.1 - 1.2 9.0 8.0 7.1 6.6 0.7 3.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 EGE04243.1 - 3 8.1 11.1 0.7 10.1 1.1 3.6 2 1 1 3 3 3 0 Zinc ribbon domain Zn-C2H2_12 PF18112.1 EGE04243.1 - 3.9 8.0 7.9 11 6.6 0.3 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 EGE04243.1 - 5.6 7.1 11.0 8.9 6.4 2.7 3.2 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_4 PF13717.6 EGE04243.1 - 7.7 6.5 10.2 23 5.0 1.4 3.8 3 1 0 3 3 3 0 zinc-ribbon domain Ca_chan_IQ PF08763.11 EGE04244.1 - 0.051 13.8 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 Voltage gated calcium channel IQ domain MFS_1 PF07690.16 EGE04246.1 - 2e-36 125.6 50.8 9.3e-35 120.2 43.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGE04246.1 - 0.0015 17.4 14.5 0.0015 17.4 14.5 2.3 2 0 0 2 2 2 1 MFS_1 like family DUF3043 PF11241.8 EGE04246.1 - 7.3 6.6 4.8 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) FAD_binding_3 PF01494.19 EGE04247.1 - 1.6e-15 57.2 0.0 3.7e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGE04247.1 - 2.9e-05 23.8 0.0 0.00017 21.3 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE04247.1 - 0.00027 21.1 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE04247.1 - 0.0006 19.1 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGE04247.1 - 0.00071 19.0 0.1 0.0052 16.2 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EGE04247.1 - 0.0011 18.2 0.0 0.0025 17.0 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGE04247.1 - 0.0016 17.3 0.0 0.0046 15.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EGE04247.1 - 0.0073 16.9 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGE04247.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 EGE04247.1 - 0.057 12.5 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 EGE04247.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DNA_pol_B PF00136.21 EGE04248.1 - 1.1e-146 489.2 3.8 1.5e-146 488.8 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGE04248.1 - 1.1e-79 268.1 0.2 2e-79 267.2 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGE04248.1 - 2e-19 69.8 3.1 4.7e-19 68.6 3.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EGE04248.1 - 0.00049 20.1 0.2 0.0025 17.8 0.2 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EGE04248.1 - 0.0089 15.7 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EGE04248.1 - 0.012 14.5 0.6 0.019 13.8 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.22 EGE04248.1 - 0.018 14.9 6.7 0.074 13.0 1.0 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ETC_C1_NDUFA5 PF04716.14 EGE04248.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ETC complex I subunit conserved region Fungal_trans_2 PF11951.8 EGE04249.1 - 5.5e-10 38.6 1.1 7.5e-09 34.9 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE04249.1 - 7e-08 32.5 9.9 1.2e-07 31.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGE04250.1 - 4.5e-25 88.5 0.0 6.2e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04250.1 - 5.4e-11 42.3 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase IBV_3C PF03620.13 EGE04251.1 - 0.019 15.4 0.5 0.049 14.1 0.1 1.9 2 0 0 2 2 2 0 IBV 3C protein DUF1772 PF08592.11 EGE04251.1 - 0.021 15.2 3.8 0.051 13.9 3.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Glyco_hydro_47 PF01532.20 EGE04252.1 - 2.4e-182 607.0 0.0 2.8e-182 606.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TAtT PF16811.5 EGE04252.1 - 0.15 11.3 0.1 0.6 9.3 0.0 1.8 2 0 0 2 2 2 0 TRAP transporter T-component LIP PF03583.14 EGE04253.1 - 3.2e-79 266.2 0.0 4.2e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Syja_N PF02383.18 EGE04254.1 - 5e-77 259.3 0.0 8.3e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 EGE04255.1 - 3.2e-89 299.2 2.1 1.5e-88 297.1 1.0 2.0 2 0 0 2 2 2 1 Tti2 family PolyA_pol PF01743.20 EGE04256.1 - 5.4e-24 85.0 0.1 1.5e-23 83.6 0.1 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGE04256.1 - 2.6e-07 30.3 0.0 6.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EGE04256.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative CdiI_2 PF18593.1 EGE04256.1 - 0.092 13.4 0.0 0.66 10.7 0.0 2.4 2 0 0 2 2 2 0 CdiI immunity protein DUF5071 PF16804.5 EGE04256.1 - 0.13 12.5 0.4 0.54 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Glyco_transf_8C PF08437.10 EGE04256.1 - 0.21 11.7 0.1 0.5 10.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal TRAPPC-Trs85 PF12739.7 EGE04257.1 - 3.5e-110 368.8 0.0 2.6e-108 362.6 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.21 EGE04260.1 - 4.9e-17 62.1 10.8 4.9e-17 62.1 10.8 2.2 1 1 1 2 2 2 1 Snf7 LPP PF04728.13 EGE04260.1 - 0.58 10.6 3.9 0.59 10.6 0.2 3.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EGE04260.1 - 0.78 10.0 12.9 35 4.7 6.5 3.7 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C3HC4_2 PF13923.6 EGE04261.1 - 3.1e-10 39.7 22.2 1e-09 38.0 15.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE04261.1 - 3.4e-07 30.0 13.2 3.4e-07 30.0 13.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGE04261.1 - 1e-06 28.5 7.8 1e-06 28.5 7.8 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 EGE04261.1 - 2.4e-06 27.3 17.0 2.4e-06 27.3 17.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE04261.1 - 1.2e-05 25.2 16.4 1.2e-05 25.2 16.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.27 EGE04261.1 - 1.3e-05 24.8 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 EGE04261.1 - 2e-05 24.8 22.1 4.1e-05 23.8 17.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGE04261.1 - 0.00013 22.0 22.3 0.00013 22.0 16.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGE04261.1 - 0.00048 20.2 20.4 0.00073 19.6 17.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGE04261.1 - 0.00048 19.9 17.0 0.1 12.5 15.0 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 U-box PF04564.15 EGE04261.1 - 0.02 15.1 0.0 0.076 13.2 0.0 2.0 2 0 0 2 2 1 0 U-box domain Mob_synth_C PF06463.13 EGE04261.1 - 0.031 14.2 5.3 0.066 13.1 5.3 1.5 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C Rad50_zn_hook PF04423.14 EGE04261.1 - 0.14 12.0 3.6 5.9 6.8 1.4 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EGE04261.1 - 0.19 11.8 5.2 0.49 10.5 5.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGE04261.1 - 0.44 10.9 16.9 0.065 13.5 11.8 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 EGE04261.1 - 1.8 9.3 5.2 3.7 8.4 0.2 2.8 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_10 PF16685.5 EGE04261.1 - 5.9 7.1 13.8 0.32 11.2 8.1 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 CDC27 PF09507.10 EGE04262.1 - 6.8e-86 289.3 26.1 8e-86 289.1 26.1 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 EGE04263.1 - 9.5e-169 561.7 0.0 1.1e-168 561.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) RRM_1 PF00076.22 EGE04264.1 - 0.0021 17.8 0.0 1.2 9.0 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMD3 PF04981.13 EGE04265.1 - 2.1e-79 266.4 4.2 3.8e-79 265.6 4.2 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 EGE04265.1 - 0.44 10.6 9.6 2.1 8.4 1.3 3.1 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rhodanese_C PF12368.8 EGE04265.1 - 9.6 6.7 9.5 5.2 7.5 6.3 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal RsfS PF02410.15 EGE04266.1 - 4.4e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Pex2_Pex12 PF04757.14 EGE04267.1 - 2.2e-54 184.4 2.3 3e-54 184.0 2.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EGE04267.1 - 5.1e-06 26.5 2.8 9.2e-06 25.7 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGE04267.1 - 0.00066 20.0 1.1 0.0014 19.0 1.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE04267.1 - 0.00074 19.3 1.8 0.0014 18.4 1.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE04267.1 - 0.002 18.1 2.4 0.002 18.1 2.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGE04267.1 - 0.0022 17.8 1.1 0.0043 16.9 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE04267.1 - 0.0033 17.2 1.4 0.0064 16.3 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 EGE04267.1 - 3.3 8.0 4.8 6.5 7.0 4.8 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mito_carr PF00153.27 EGE04268.1 - 8.6e-60 198.7 3.4 1.7e-21 75.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGE04268.1 - 0.026 13.7 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WAC_Acf1_DNA_bd PF10537.9 EGE04269.1 - 5.2e-34 116.8 1.1 1.2e-33 115.6 0.1 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EGE04269.1 - 4.2e-23 81.7 0.5 4.2e-23 81.7 0.5 3.4 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EGE04269.1 - 3.3e-17 62.5 1.5 6.9e-17 61.5 1.5 1.5 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EGE04269.1 - 4.8e-10 38.7 0.0 1.2e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DIT1_PvcA PF05141.12 EGE04269.1 - 4.3 6.7 6.7 13 5.2 6.7 1.8 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein CtIP_N PF10482.9 EGE04269.1 - 4.8 7.3 13.8 2.1 8.4 1.1 3.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Alg6_Alg8 PF03155.15 EGE04270.1 - 2.8e-173 577.4 26.3 3.2e-173 577.1 26.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 EGE04271.1 - 9.5e-25 87.3 0.0 1.3e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Dynamitin PF04912.14 EGE04271.1 - 0.0092 15.3 1.7 0.012 14.9 1.7 1.1 1 0 0 1 1 1 1 Dynamitin TMF_TATA_bd PF12325.8 EGE04271.1 - 0.011 16.0 3.0 0.017 15.3 3.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4349 PF14257.6 EGE04271.1 - 0.015 14.8 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ALMT PF11744.8 EGE04271.1 - 0.027 13.3 0.7 0.04 12.8 0.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Sperm_Ag_HE2 PF05324.13 EGE04271.1 - 0.061 13.8 0.0 9.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Sperm antigen HE2 WXG100 PF06013.12 EGE04271.1 - 0.11 12.7 0.2 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FUSC PF04632.12 EGE04271.1 - 0.26 9.8 0.6 0.35 9.4 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF5385 PF17359.2 EGE04271.1 - 1.1 8.8 3.1 0.86 9.1 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5385) YlbD_coat PF14071.6 EGE04271.1 - 1.8 8.8 5.2 2.8 8.2 0.9 2.2 1 1 1 2 2 2 0 Putative coat protein APG6_N PF17675.1 EGE04271.1 - 2 9.0 4.1 5.1 7.6 4.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region PHD PF00628.29 EGE04272.1 - 1e-17 63.7 16.6 2.5e-11 43.3 6.6 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EGE04272.1 - 0.15 11.7 12.2 0.48 10.0 2.7 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EGE04272.1 - 0.46 10.8 4.5 1.8 8.9 1.1 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EGE04272.1 - 1 9.0 8.9 0.76 9.4 1.2 3.2 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 EGE04272.1 - 6.6 6.7 6.5 23 5.0 1.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) S-antigen PF05756.11 EGE04273.1 - 0.017 15.4 2.0 0.045 14.1 2.0 1.7 1 0 0 1 1 1 0 S-antigen protein Ribosomal_60s PF00428.19 EGE04273.1 - 0.053 14.1 4.7 0.082 13.5 4.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Exo_endo_phos PF03372.23 EGE04274.1 - 1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 EGE04275.1 - 3.9e-64 216.7 0.2 8e-63 212.4 0.0 2.4 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 EGE04275.1 - 0.00021 21.3 2.2 0.00021 21.3 2.2 3.4 3 1 1 4 4 4 1 INO80 complex subunit Ies4 HEAT_2 PF13646.6 EGE04276.1 - 4.3e-08 33.4 3.0 1.1e-06 29.0 0.8 3.6 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGE04276.1 - 8.8e-06 25.6 8.2 0.17 12.2 0.1 5.6 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EGE04276.1 - 1.3e-05 25.3 0.3 0.0025 17.9 0.1 4.4 4 1 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGE04276.1 - 0.026 15.1 10.6 0.085 13.4 0.3 5.1 6 0 0 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 EGE04276.1 - 0.031 13.8 0.0 1.5 8.3 0.0 2.9 1 1 1 2 2 2 0 CLASP N terminal DUF3734 PF12536.8 EGE04276.1 - 0.037 14.4 0.2 0.82 10.0 0.0 3.2 2 0 0 2 2 2 0 Patatin phospholipase Arena_ncap_C PF17290.2 EGE04276.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain DTHCT PF08070.11 EGE04276.1 - 0.27 12.0 21.4 0.13 13.0 15.3 3.2 3 0 0 3 3 3 0 DTHCT (NUC029) region MFS_1 PF07690.16 EGE04277.1 - 3e-37 128.4 33.5 3e-37 128.4 33.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04277.1 - 3e-05 23.1 11.8 3e-05 23.1 11.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter ATP-synt_8 PF00895.20 EGE04277.1 - 6.7 7.2 7.3 1.9 9.0 2.0 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 Ank_5 PF13857.6 EGE04278.1 - 8.7e-18 64.2 1.0 3.3e-07 30.4 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE04278.1 - 8.1e-14 51.8 0.2 6.4e-07 29.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04278.1 - 3.3e-11 42.4 0.8 0.098 13.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EGE04278.1 - 6.9e-11 42.6 0.1 2.8e-06 27.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGE04278.1 - 1.4e-07 31.7 0.1 0.054 14.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Phlebovirus_G1 PF07243.11 EGE04278.1 - 0.0058 15.1 0.0 0.0074 14.7 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G1 UDPG_MGDP_dh_C PF03720.15 EGE04278.1 - 0.046 14.2 0.1 0.51 10.8 0.1 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PHD PF00628.29 EGE04279.1 - 3.1e-09 36.6 8.4 3.1e-09 36.6 8.4 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EGE04279.1 - 1.4e-08 34.9 1.5 1.4e-08 34.9 1.5 3.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EGE04279.1 - 7.8e-07 29.3 1.0 7.8e-07 29.3 1.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGE04279.1 - 4e-06 26.6 2.0 4e-06 26.6 2.0 2.9 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE04279.1 - 9.1e-06 25.4 2.0 9.1e-06 25.4 2.0 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EGE04279.1 - 1.7e-05 24.2 3.9 4.1e-05 23.0 3.9 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 EGE04279.1 - 3.1e-05 23.8 1.9 3.1e-05 23.8 1.9 2.6 2 2 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGE04279.1 - 5e-05 23.1 1.5 5e-05 23.1 1.5 2.6 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGE04279.1 - 7.9e-05 22.4 1.0 7.9e-05 22.4 1.0 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGE04279.1 - 0.00048 20.1 0.3 0.00048 20.1 0.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGE04279.1 - 0.0024 17.8 1.9 0.0024 17.8 1.9 3.8 2 2 1 3 3 2 1 RING-type zinc-finger zf-PHD-like PF15446.6 EGE04279.1 - 0.19 11.4 5.3 0.073 12.7 2.0 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.11 EGE04279.1 - 4.5 7.7 9.2 2.8 8.3 1.7 2.6 2 0 0 2 2 2 0 RING-like domain DUF1644 PF07800.12 EGE04279.1 - 6.1 6.9 7.7 12 5.9 4.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Zn_ribbon_17 PF17120.5 EGE04279.1 - 6.7 6.4 9.9 0.4 10.4 1.5 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EGE04279.1 - 9.1 6.2 10.0 0.15 11.8 1.1 2.5 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain Ribosomal_L37ae PF01780.19 EGE04280.1 - 4.3e-40 135.7 11.9 4.8e-40 135.5 11.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EGE04280.1 - 0.00032 20.8 1.6 0.00043 20.4 1.6 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EGE04280.1 - 0.0031 17.4 2.8 0.0052 16.7 2.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 EGE04280.1 - 0.014 15.4 0.5 0.02 14.9 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-BED PF02892.15 EGE04280.1 - 0.028 14.4 4.6 1.2 9.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger Sacchrp_dh_NADP PF03435.18 EGE04281.1 - 2.8e-17 63.2 0.0 5.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EGE04281.1 - 0.011 16.2 0.0 0.08 13.4 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FIT1_2 PF17357.2 EGE04281.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 Abhydrolase_1 PF00561.20 EGE04282.1 - 2.7e-09 37.1 0.2 1e-07 31.9 0.1 2.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE04282.1 - 1e-05 26.2 0.0 0.00011 22.9 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE04282.1 - 0.0068 15.7 0.0 4.4 6.5 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Pinin_SDK_memA PF04696.13 EGE04283.1 - 6.1e-32 110.4 4.9 6.1e-32 110.4 4.9 1.7 1 1 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DIOX_N PF14226.6 EGE04284.1 - 5.2e-30 104.6 0.0 8e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE04284.1 - 4.4e-20 72.1 0.0 9.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2141 PF09912.9 EGE04284.1 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) Myb_DNA-binding PF00249.31 EGE04285.1 - 5.6e-30 103.3 16.2 4.2e-11 42.8 0.6 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE04285.1 - 4.5e-29 100.5 10.7 2.1e-13 50.3 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EGE04285.1 - 0.0003 21.0 9.2 0.23 11.8 0.5 3.9 3 1 0 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 EGE04285.1 - 0.0074 16.3 4.7 3 8.0 0.2 3.5 1 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGE04285.1 - 0.029 14.4 0.0 0.36 10.8 0.0 2.5 1 1 2 3 3 3 0 SLIDE MFS_1 PF07690.16 EGE04286.1 - 8.9e-34 116.9 45.6 5.1e-33 114.5 45.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE04286.1 - 9.1e-12 44.2 10.4 9.1e-12 44.2 10.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EGE04287.1 - 2.5e-56 191.3 0.0 3.2e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EGE04288.1 - 2e-72 243.8 0.0 3.4e-72 243.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EGE04288.1 - 4.8e-34 116.1 0.7 1.3e-33 114.7 0.3 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 EGE04288.1 - 2.4e-32 111.4 0.0 5.4e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EGE04288.1 - 1.8e-25 90.1 0.0 4.1e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGE04288.1 - 2.8e-21 75.8 0.0 6.4e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 EGE04288.1 - 7e-19 68.5 0.1 3.4e-12 46.6 0.0 2.6 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 EGE04288.1 - 1.3e-13 51.6 0.0 3.2e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04288.1 - 6.2e-11 42.9 0.0 2.3e-10 41.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EGE04288.1 - 9e-10 38.8 0.3 2.6e-09 37.3 0.3 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGE04288.1 - 1.1e-09 38.3 0.0 2.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE04288.1 - 3.5e-09 37.2 0.0 1.2e-08 35.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE04288.1 - 8.8e-09 35.4 0.0 3.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EGE04288.1 - 2.7e-07 30.2 0.3 2.8e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGE04288.1 - 1.3e-05 24.7 0.0 0.00058 19.3 0.0 3.3 4 0 0 4 4 4 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.21 EGE04288.1 - 2.1e-05 24.1 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EGE04288.1 - 0.00031 21.2 0.0 0.00079 19.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 EGE04288.1 - 0.00076 18.7 0.1 0.014 14.5 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Methyltransf_32 PF13679.6 EGE04288.1 - 0.038 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.10 EGE04288.1 - 0.05 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 KR domain DXP_reductoisom PF02670.16 EGE04288.1 - 0.058 14.1 0.3 0.17 12.6 0.0 1.9 2 0 0 2 2 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NodS PF05401.11 EGE04288.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) RmlD_sub_bind PF04321.17 EGE04288.1 - 0.14 11.3 0.0 10 5.1 0.0 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain Pkinase PF00069.25 EGE04289.1 - 6.1e-20 71.7 0.0 7.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04289.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE04289.1 - 8.1e-06 24.9 0.3 1.2e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE04289.1 - 0.00058 19.9 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE04289.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Antimicrobial15 PF08110.12 EGE04289.1 - 0.12 12.7 0.7 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Ocellatin family PHF5 PF03660.14 EGE04290.1 - 4.3e-52 174.7 9.5 4.9e-52 174.5 9.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGE04290.1 - 0.6 7.9 7.2 0.63 7.8 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EGE04290.1 - 1.9 8.6 15.3 2.3 8.3 1.1 3.0 1 1 1 2 2 2 0 Double zinc ribbon Cofilin_ADF PF00241.20 EGE04291.1 - 4.6e-29 100.7 0.0 7e-16 58.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.27 EGE04292.1 - 1.5e-66 220.3 1.2 2.3e-22 78.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CAF1 PF04857.20 EGE04293.1 - 2.1e-84 283.5 0.0 2.6e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease HDA2-3 PF11496.8 EGE04293.1 - 0.073 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DNA_pol_A_exo1 PF01612.20 EGE04293.1 - 0.1 12.3 0.0 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease TFIIF_alpha PF05793.12 EGE04294.1 - 0.0028 16.3 16.4 0.0044 15.7 16.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.13 EGE04294.1 - 0.067 13.1 20.4 0.12 12.2 20.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 EGE04294.1 - 0.086 11.1 13.9 0.13 10.5 13.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1266 PF06889.11 EGE04294.1 - 0.45 10.5 5.5 0.86 9.6 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) FAM220 PF15487.6 EGE04294.1 - 1.2 8.7 12.2 2.8 7.5 12.2 1.6 1 0 0 1 1 1 0 FAM220 family Folliculin PF11704.8 EGE04294.1 - 1.7 8.5 8.8 4.8 7.0 8.8 1.8 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport APG6_N PF17675.1 EGE04294.1 - 2 8.9 24.5 5.1 7.6 24.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Presenilin PF01080.17 EGE04294.1 - 3 6.5 12.8 5.5 5.6 12.8 1.4 1 0 0 1 1 1 0 Presenilin FAM178 PF14816.6 EGE04294.1 - 3.1 6.7 15.2 7.4 5.4 15.2 1.6 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF4407 PF14362.6 EGE04294.1 - 3.2 7.0 7.7 5.7 6.2 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 EGE04294.1 - 6.5 5.4 13.9 10 4.8 13.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.11 EGE04294.1 - 7.1 5.0 18.3 10 4.5 18.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 EGE04294.1 - 7.3 6.3 23.2 2.2 8.0 20.1 1.6 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRP-L46 PF11788.8 EGE04295.1 - 2.4e-38 131.5 0.2 3.7e-38 130.9 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cript PF10235.9 EGE04296.1 - 4.5e-24 84.8 9.9 4.5e-24 84.8 9.9 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EGE04296.1 - 0.0042 17.1 15.0 0.41 10.7 10.3 3.0 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGE04296.1 - 0.018 15.8 12.8 0.051 14.3 9.6 2.7 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 EGE04296.1 - 0.29 10.9 8.7 9.5 6.1 0.8 3.4 2 1 2 4 4 4 0 zinc-ribbon domain CEBP_ZZ PF16366.5 EGE04296.1 - 0.39 11.0 8.1 0.25 11.6 4.7 2.0 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain LIM PF00412.22 EGE04296.1 - 2.1 8.7 11.3 2.2 8.6 0.1 3.5 3 1 0 3 3 3 0 LIM domain DUF1272 PF06906.11 EGE04296.1 - 2.2 8.4 8.7 0.67 10.1 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF2039 PF10217.9 EGE04296.1 - 4 7.8 17.5 2.7 8.4 11.5 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1349 PF07081.11 EGE04298.1 - 1.6e-22 80.1 0.0 3e-22 79.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) AMPK1_CBM PF16561.5 EGE04300.1 - 1.9e-07 31.2 0.1 4.7e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase JIP_LZII PF16471.5 EGE04301.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II PARM PF17061.5 EGE04301.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.3 2 1 1 3 3 3 0 PARM NOC3p PF07540.11 EGE04302.1 - 3e-29 101.3 0.4 1.6e-28 99.0 0.3 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EGE04302.1 - 4.5e-26 91.9 1.6 7.3e-25 87.9 0.0 2.9 2 1 1 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.20 EGE04302.1 - 0.02 13.4 1.3 4.8 5.6 0.0 3.0 3 0 0 3 3 3 0 Adaptin N terminal region Orbi_VP1 PF05788.12 EGE04302.1 - 0.046 11.3 0.2 0.068 10.8 0.2 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) UPF0113_N PF17833.1 EGE04303.1 - 2.8e-25 88.7 0.0 3.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGE04303.1 - 1.7e-23 82.6 0.0 2.5e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EGE04303.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain Cullin_binding PF03556.15 EGE04304.1 - 4.8e-31 107.7 3.6 7.4e-31 107.1 3.6 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EGE04304.1 - 1.4e-14 53.7 0.4 2.7e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 EGE04304.1 - 0.0046 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain CUE PF02845.16 EGE04304.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 CUE domain SprT-like PF10263.9 EGE04305.1 - 9.8e-09 35.1 0.0 9.8e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 SprT-like family SUIM_assoc PF16619.5 EGE04305.1 - 0.0019 18.2 1.0 0.0047 17.0 1.0 1.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Mpv17_PMP22 PF04117.12 EGE04306.1 - 1.8e-13 50.5 1.7 1.1e-11 44.7 0.7 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family CKAP2_C PF15297.6 EGE04306.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PEX11 PF05648.14 EGE04308.1 - 8e-17 61.4 2.4 2.8e-14 53.1 0.3 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PsiF_repeat PF07769.14 EGE04310.1 - 0.1 12.5 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 psiF repeat AAA PF00004.29 EGE04313.1 - 1e-96 320.4 0.0 2e-47 160.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE04313.1 - 2.5e-24 84.8 5.5 6.7e-13 48.2 0.3 3.3 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGE04313.1 - 1e-18 67.3 1.4 2.3e-18 66.1 0.6 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EGE04313.1 - 3e-14 53.5 0.0 1.1e-07 32.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGE04313.1 - 8.9e-14 51.5 0.0 1.4e-05 24.9 0.0 3.4 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGE04313.1 - 2.6e-12 47.1 0.0 2.3e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGE04313.1 - 3.7e-11 43.7 0.0 0.00014 22.2 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGE04313.1 - 3.4e-10 40.1 0.6 4.5e-05 23.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE04313.1 - 6.4e-09 36.2 0.5 0.053 13.8 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EGE04313.1 - 7.4e-09 35.3 0.1 0.0015 17.8 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EGE04313.1 - 5e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EGE04313.1 - 3.1e-07 30.3 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGE04313.1 - 4.4e-07 29.5 0.4 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGE04313.1 - 1.1e-06 29.2 0.0 0.055 14.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 EGE04313.1 - 1.1e-06 28.2 0.4 0.64 9.3 0.0 3.5 3 0 0 3 3 3 2 KaiC Vps4_C PF09336.10 EGE04313.1 - 1.7e-06 27.9 0.4 1.7e-05 24.7 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EGE04313.1 - 1.9e-06 28.2 0.0 0.028 14.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGE04313.1 - 2.5e-06 27.5 0.0 0.023 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGE04313.1 - 4.4e-06 26.4 6.5 0.43 10.1 0.1 4.9 3 2 1 5 5 5 2 AAA domain AAA_7 PF12775.7 EGE04313.1 - 7.1e-06 25.7 0.1 0.035 13.6 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EGE04313.1 - 3e-05 24.3 0.0 0.3 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EGE04313.1 - 3.7e-05 23.0 0.0 0.0086 15.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGE04313.1 - 4.8e-05 23.9 0.0 0.26 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 EGE04313.1 - 7e-05 22.6 0.1 0.75 9.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 EGE04313.1 - 8.3e-05 22.1 0.4 0.35 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 EGE04313.1 - 8.4e-05 22.4 0.0 0.66 9.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EGE04313.1 - 0.00011 21.5 0.1 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EGE04313.1 - 0.00026 20.9 0.0 0.69 9.7 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.6 EGE04313.1 - 0.00031 20.6 0.0 0.41 10.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain ResIII PF04851.15 EGE04313.1 - 0.00041 20.4 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 EGE04313.1 - 0.00045 20.6 0.0 0.88 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGE04313.1 - 0.0006 19.8 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGE04313.1 - 0.00072 19.4 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGE04313.1 - 0.0018 17.6 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGE04313.1 - 0.0039 16.9 0.6 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGE04313.1 - 0.0044 17.0 0.0 11 5.8 0.0 3.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGE04313.1 - 0.0054 17.1 0.7 6.9 7.0 0.0 3.5 3 1 0 4 4 2 0 AAA domain NACHT PF05729.12 EGE04313.1 - 0.0071 16.3 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 EGE04313.1 - 0.008 15.9 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UFD1 PF03152.14 EGE04313.1 - 0.0086 15.6 0.0 0.069 12.6 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 EGE04313.1 - 0.019 14.2 0.0 0.73 9.0 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 EGE04313.1 - 0.022 14.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGE04313.1 - 0.026 13.8 1.5 6.2 6.0 0.0 3.1 4 0 0 4 4 3 0 Zeta toxin NB-ARC PF00931.22 EGE04313.1 - 0.026 13.7 0.0 1.9 7.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain IPT PF01745.16 EGE04313.1 - 0.029 13.8 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase eIF-1a PF01176.19 EGE04313.1 - 0.03 14.1 0.8 1.1 9.2 0.7 2.8 2 1 0 2 2 1 0 Translation initiation factor 1A / IF-1 NTPase_1 PF03266.15 EGE04313.1 - 0.051 13.5 3.0 3.7 7.4 0.0 4.1 5 0 0 5 5 4 0 NTPase T2SSE PF00437.20 EGE04313.1 - 0.082 12.0 0.0 3.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EGE04313.1 - 0.084 12.6 0.2 18 5.0 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase LXG PF04740.12 EGE04313.1 - 0.089 12.5 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily AAA_6 PF12774.7 EGE04313.1 - 0.11 11.4 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Zot PF05707.12 EGE04313.1 - 0.14 11.8 0.0 7 6.2 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) EnY2 PF10163.9 EGE04314.1 - 8.6e-08 32.5 0.0 1.8e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 EGE04315.1 - 3.1e-15 56.0 0.0 5.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EGE04315.1 - 5.4e-12 46.2 0.1 1.3e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 EGE04315.1 - 7.8e-12 45.5 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 EGE04315.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nha1_C PF08619.10 EGE04316.1 - 1.7e-79 268.2 17.0 2.3e-79 267.8 17.0 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EGE04316.1 - 8.3e-73 245.4 19.3 9.9e-73 245.1 19.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EGE04316.1 - 0.024 14.7 0.4 0.024 14.7 0.4 2.4 3 0 0 3 3 3 0 YrhC-like protein DUF21 PF01595.20 EGE04316.1 - 6.9 6.3 7.7 0.52 10.0 2.4 1.9 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain PX PF00787.24 EGE04317.1 - 8.7e-16 57.9 0.2 1.7e-15 57.0 0.2 1.5 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 EGE04317.1 - 1.7 7.7 8.2 0.071 12.2 0.9 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AAA PF00004.29 EGE04318.1 - 5.7e-08 33.3 3.2 2.2e-07 31.4 0.9 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGE04318.1 - 8.5e-08 32.3 0.2 0.00041 20.3 0.1 3.3 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGE04318.1 - 0.0021 18.4 0.0 0.0063 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGE04318.1 - 0.013 15.8 0.0 0.054 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGE04318.1 - 0.22 10.7 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Utp8 PF10395.9 EGE04319.1 - 1e-08 34.2 0.3 8.4e-08 31.2 0.0 2.3 3 0 0 3 3 3 1 Utp8 family Fungal_trans PF04082.18 EGE04320.1 - 8.7e-23 80.7 0.7 1.6e-22 79.8 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGE04320.1 - 2.5e-09 37.1 14.0 7.4e-05 23.0 2.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE04320.1 - 1.5e-06 28.3 12.4 3.2e-06 27.3 6.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE04320.1 - 0.00032 21.3 13.1 0.042 14.7 2.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger CAF1C_H4-bd PF12265.8 EGE04324.1 - 7.5e-16 58.2 0.1 3.7e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGE04324.1 - 7.7e-14 51.9 7.9 2.7e-06 28.0 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04324.1 - 1.2e-07 31.9 1.7 0.001 19.3 0.3 3.1 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE04324.1 - 0.017 13.8 0.9 0.13 10.9 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 UL41A PF17591.2 EGE04324.1 - 0.21 11.7 0.0 0.72 10.0 0.0 1.9 1 0 0 1 1 1 0 Herpesvirus UL41A Vpu PF00558.19 EGE04324.1 - 0.32 10.8 1.7 0.65 9.8 1.7 1.4 1 0 0 1 1 1 0 Vpu protein Ras PF00071.22 EGE04325.1 - 8.4e-31 106.8 0.2 1.2e-30 106.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE04325.1 - 3.3e-23 82.2 0.1 3.3e-23 82.2 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE04325.1 - 2.2e-06 27.2 0.1 3.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGE04325.1 - 0.00051 19.5 0.2 0.00051 19.5 0.2 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGE04325.1 - 0.0017 17.3 0.1 1 8.1 0.0 2.3 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) CrgA PF06781.12 EGE04325.1 - 0.05 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Cell division protein CrgA TFIIA PF03153.13 EGE04325.1 - 0.1 12.6 28.6 0.14 12.1 28.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 EGE04325.1 - 0.13 11.3 13.7 0.19 10.8 13.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SRP9-21 PF05486.12 EGE04325.1 - 1.7 9.1 5.8 0.43 11.0 0.5 2.5 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Transglut_core PF01841.19 EGE04326.1 - 2.9e-14 53.5 0.0 6.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sugar_tr PF00083.24 EGE04328.1 - 2.5e-111 372.7 16.3 3e-111 372.5 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE04328.1 - 7.7e-26 90.9 32.0 2.5e-25 89.2 22.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EGE04328.1 - 6e-06 25.4 0.3 1.1e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EGE04328.1 - 0.0048 15.4 0.9 0.0091 14.5 0.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EGE04328.1 - 2.4 8.4 7.3 0.68 10.2 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TRAM_LAG1_CLN8 PF03798.16 EGE04329.1 - 4.6e-39 134.2 18.4 7.5e-39 133.5 18.4 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EGE04329.1 - 1.2e-21 76.2 0.0 3.3e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein REC114-like PF15165.6 EGE04330.1 - 0.35 10.6 2.4 0.58 9.9 2.4 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like SAPS PF04499.15 EGE04330.1 - 2.4 6.8 6.2 2.5 6.8 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.9 EGE04330.1 - 3.9 6.2 26.7 4.6 6.0 26.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TIP120 PF08623.10 EGE04331.1 - 1.6e-66 223.3 0.0 5.3e-64 215.0 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EGE04331.1 - 2.4e-14 52.2 5.2 0.13 12.6 0.0 9.3 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 EGE04331.1 - 3.4e-10 40.2 6.9 0.46 10.9 0.0 7.7 7 2 2 9 9 8 3 HEAT repeats HEAT_EZ PF13513.6 EGE04331.1 - 4.6e-07 30.2 11.7 2.3 8.8 0.0 10.0 10 1 2 12 12 12 2 HEAT-like repeat Cnd1 PF12717.7 EGE04331.1 - 8.8e-07 29.1 0.1 0.00016 21.7 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGE04331.1 - 3.9e-05 22.4 1.8 1.7 7.1 0.0 5.2 4 2 1 5 5 5 2 Adaptin N terminal region RTP1_C1 PF10363.9 EGE04331.1 - 0.0011 19.2 0.5 0.13 12.4 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EGE04331.1 - 0.0019 18.8 0.0 7.1 7.3 0.0 5.6 6 2 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3295 PF11702.8 EGE04331.1 - 0.016 14.6 0.2 0.028 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DRIM PF07539.12 EGE04331.1 - 0.058 11.7 3.5 22 3.2 0.0 4.7 4 1 0 5 5 5 0 Down-regulated in metastasis Arm PF00514.23 EGE04331.1 - 1 9.5 6.9 25 5.1 0.0 5.5 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 EGE04331.1 - 1.2 8.1 11.9 1.2 8.2 1.8 4.4 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.16 EGE04331.1 - 9.5 7.2 10.0 0.87 10.4 0.3 4.7 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat PalH PF08733.10 EGE04333.1 - 2e-113 378.8 0.0 2.6e-113 378.4 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 BUD22 PF09073.10 EGE04333.1 - 0.065 12.6 4.0 0.088 12.1 4.0 1.1 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 EGE04334.1 - 1.2e-05 25.1 0.5 3e-05 23.8 0.2 2.0 2 0 0 2 2 2 1 F-box-like SOG2 PF10428.9 EGE04334.1 - 0.42 9.8 10.5 0.25 10.5 6.8 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein Zn_clus PF00172.18 EGE04335.1 - 5.6e-07 29.6 14.8 9.3e-07 28.9 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.9 EGE04336.1 - 5.3e-17 61.9 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EGE04336.1 - 9.8e-07 28.0 1.0 0.021 13.7 0.0 3.2 3 0 0 3 3 3 3 Vacuolar protein sorting 38 Mhr1 PF12829.7 EGE04337.1 - 7e-27 93.3 0.1 1.5e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RR_TM4-6 PF06459.12 EGE04337.1 - 5.2 6.8 10.7 8.8 6.1 10.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PP2C PF00481.21 EGE04338.1 - 9.1e-63 212.3 1.6 7.1e-50 170.0 0.0 3.9 2 1 1 3 3 3 2 Protein phosphatase 2C AAA_33 PF13671.6 EGE04338.1 - 0.023 14.9 0.0 0.093 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.21 EGE04340.1 - 2.4e-35 121.7 17.5 1.8e-34 118.8 15.8 2.0 2 0 0 2 2 2 1 Snf7 DUF3958 PF13125.6 EGE04340.1 - 6.9 6.9 13.1 0.19 11.9 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Remorin_C PF03763.13 EGE04340.1 - 8.1 6.4 12.7 0.49 10.3 7.2 1.9 2 1 0 2 2 2 0 Remorin, C-terminal region Dynamin_N PF00350.23 EGE04341.1 - 2.9e-17 63.2 4.6 2.9e-17 63.2 0.1 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGE04341.1 - 1.7e-10 41.0 0.0 1.1e-08 35.2 0.0 3.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGE04341.1 - 1.3e-07 31.4 0.1 9.1e-05 22.1 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 EGE04341.1 - 0.034 14.1 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Short coiled-coil protein FeoB_N PF02421.18 EGE04341.1 - 0.065 12.8 0.4 39 3.7 0.0 3.8 5 0 0 5 5 5 0 Ferrous iron transport protein B AAA_18 PF13238.6 EGE04341.1 - 0.07 13.7 0.0 0.58 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGE04341.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EGE04341.1 - 0.1 12.8 0.1 3 8.1 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGE04341.1 - 0.15 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PTCB-BRCT PF12738.7 EGE04342.1 - 4e-45 151.6 0.6 8.8e-22 76.8 0.1 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EGE04342.1 - 1.4e-28 99.1 0.0 4.2e-11 43.1 0.1 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGE04342.1 - 2.7e-10 40.5 0.0 0.00024 21.5 0.0 4.1 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGE04342.1 - 2.8e-05 24.3 2.2 0.19 12.0 0.0 3.9 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain PIF1 PF05970.14 EGE04343.1 - 3.5e-63 214.0 0.2 2.5e-47 161.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EGE04343.1 - 1e-24 87.3 0.0 1.8e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE04343.1 - 1.9e-11 44.5 0.1 2.5e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE04343.1 - 1.6e-06 28.4 0.0 5.2e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGE04343.1 - 6.2e-05 22.6 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EGE04343.1 - 0.00021 21.7 0.3 0.00068 20.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 EGE04343.1 - 0.00023 19.2 0.0 0.0011 17.0 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EGE04343.1 - 0.00025 20.8 0.1 0.00076 19.3 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGE04343.1 - 0.0025 17.6 0.1 0.6 9.8 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 EGE04343.1 - 0.0048 16.9 0.1 0.024 14.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGE04343.1 - 0.0074 16.3 0.1 0.036 14.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGE04343.1 - 0.012 16.0 0.3 0.042 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PhoH PF02562.16 EGE04343.1 - 0.016 14.7 0.2 0.053 13.0 0.0 2.0 2 0 0 2 2 1 0 PhoH-like protein DUF2075 PF09848.9 EGE04343.1 - 0.038 13.2 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGE04343.1 - 0.047 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 EGE04343.1 - 0.051 12.8 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 EGE04343.1 - 0.056 13.3 0.0 0.23 11.3 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RNA_helicase PF00910.22 EGE04343.1 - 0.061 13.7 0.0 0.34 11.3 0.0 2.4 2 1 0 2 2 1 0 RNA helicase DUF5605 PF18310.1 EGE04343.1 - 0.07 13.0 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) RsgA_GTPase PF03193.16 EGE04343.1 - 0.072 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EGE04343.1 - 0.12 12.3 0.7 0.6 10.0 0.7 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Pro_isomerase PF00160.21 EGE04347.1 - 2.7e-33 115.5 0.0 5.3e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EGE04347.1 - 0.00018 21.6 0.0 0.00046 20.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EGE04347.1 - 0.00052 20.1 0.0 0.0022 18.2 0.0 2.0 1 1 0 1 1 1 1 U-box domain Rtf2 PF04641.12 EGE04347.1 - 0.0022 17.4 0.7 0.0022 17.4 0.7 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger DUF3340 PF11818.8 EGE04347.1 - 1 9.5 7.1 0.074 13.2 1.6 1.8 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Pkinase PF00069.25 EGE04348.1 - 5.8e-16 58.7 0.2 2.1e-13 50.3 0.1 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04348.1 - 4.1e-10 39.4 0.0 2.4e-07 30.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 EGE04348.1 - 5.1e-06 26.2 0.1 9e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family YjeF_N PF03853.15 EGE04349.1 - 1.4e-33 116.2 0.1 2.1e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EGE04349.1 - 1.1e-06 29.5 0.7 1.1e-06 29.5 0.7 2.4 3 0 0 3 3 3 1 FDF domain OCD_Mu_crystall PF02423.15 EGE04349.1 - 0.045 12.7 0.2 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family MDM10 PF12519.8 EGE04350.1 - 7.9e-144 480.0 3.3 1.7e-125 419.6 1.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 EGE04351.1 - 8.6e-90 300.3 0.5 9.8e-90 300.2 0.5 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3860 PF12976.7 EGE04351.1 - 0.043 13.8 1.1 0.072 13.1 0.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) RL10P_insert PF17777.1 EGE04352.1 - 9.2e-22 76.8 0.0 1.8e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGE04352.1 - 9.7e-19 67.4 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 EGE04353.1 - 6.5e-28 97.2 1.0 1.5e-27 96.1 1.0 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EGE04353.1 - 7e-17 61.0 0.0 1.4e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE04353.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 EGE04354.1 - 1.7e-16 59.9 0.3 2.5e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Prp19 PF08606.11 EGE04355.1 - 2.8e-33 113.7 1.2 4.9e-33 112.9 1.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EGE04355.1 - 1.4e-11 44.5 0.0 2.9e-06 27.5 0.0 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE04355.1 - 2.2e-10 41.0 6.3 3.3e-05 24.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGE04355.1 - 7.5e-05 21.9 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 EGE04355.1 - 0.00013 21.9 0.0 0.074 12.9 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 EGE04355.1 - 0.00035 20.9 0.2 0.00069 20.0 0.2 1.4 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain Cytochrom_D1 PF02239.16 EGE04355.1 - 0.079 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGE04355.1 - 0.081 11.9 0.0 0.21 10.5 0.0 1.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EGE04355.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain ECH_1 PF00378.20 EGE04357.1 - 1.9e-47 161.7 0.0 2.4e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE04357.1 - 4.3e-24 85.6 0.1 5.4e-22 78.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Acyl-CoA_dh_1 PF00441.24 EGE04358.1 - 2.8e-31 108.7 0.1 3.9e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGE04358.1 - 1.1e-25 90.5 0.0 2.4e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGE04358.1 - 1.6e-21 76.3 0.0 2.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGE04358.1 - 0.0011 19.3 0.0 0.0016 18.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Bombinin PF05298.11 EGE04358.1 - 0.082 12.6 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Bombinin DUF846 PF05832.12 EGE04359.1 - 3.3e-48 163.2 10.1 3.9e-48 163.0 10.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) zf-CCHC PF00098.23 EGE04360.1 - 1.2e-52 173.8 101.5 1.2e-07 31.4 2.5 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_2 PF13696.6 EGE04360.1 - 5.8e-12 45.2 88.2 0.00055 19.7 0.5 11.3 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_4 PF14392.6 EGE04360.1 - 2.5e-08 33.5 65.0 0.17 11.6 0.2 11.1 11 0 0 11 11 11 7 Zinc knuckle zf-CCHC_3 PF13917.6 EGE04360.1 - 2.2e-06 27.5 78.0 0.046 13.7 0.8 11.1 3 3 8 11 11 11 8 Zinc knuckle zf-CCHC_6 PF15288.6 EGE04360.1 - 0.019 14.8 3.4 0.019 14.8 3.4 10.5 9 2 2 11 11 11 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGE04360.1 - 0.025 14.3 2.8 0.025 14.3 2.8 9.3 10 0 0 10 10 10 0 C2H2 zinc-finger ETRAMP PF09716.10 EGE04361.1 - 0.055 13.5 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sugar_tr PF00083.24 EGE04363.1 - 1.3e-102 344.0 23.7 1.6e-102 343.7 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE04363.1 - 4.4e-20 71.9 31.7 2.1e-14 53.2 6.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE04363.1 - 1.2e-05 23.8 1.1 1.2e-05 23.8 1.1 2.5 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3464 PF11947.8 EGE04363.1 - 0.002 17.9 3.6 0.0053 16.5 3.6 1.6 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 BTB PF00651.31 EGE04364.1 - 0.032 14.5 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain DUF4360 PF14273.6 EGE04365.1 - 1.2e-52 178.4 0.7 1.3e-52 178.3 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.25 EGE04366.1 - 6.4e-65 219.1 0.0 8.2e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04366.1 - 1.3e-30 106.5 0.0 9.8e-30 103.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE04366.1 - 7.7e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE04366.1 - 0.0031 16.9 0.6 0.05 12.9 0.0 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGE04366.1 - 0.0078 16.2 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGE04366.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EGE04366.1 - 0.088 12.4 0.1 4.3 6.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SR-25 PF10500.9 EGE04367.1 - 5.6e-05 22.9 11.7 0.00011 21.9 11.7 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGE04367.1 - 0.75 10.5 6.6 1.7 9.3 6.6 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein FAM199X PF15814.5 EGE04367.1 - 1.6 7.7 7.9 2.2 7.3 7.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X Amino_oxidase PF01593.24 EGE04369.1 - 1.3e-08 34.5 0.0 2.5e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE04369.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE04369.1 - 0.0014 17.9 0.1 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE04369.1 - 0.0089 15.3 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE04369.1 - 0.014 14.6 0.1 0.033 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGE04369.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGE04369.1 - 0.046 13.0 0.1 0.072 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 EGE04369.1 - 0.077 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EGE04369.1 - 0.093 11.8 0.4 0.27 10.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 EGE04369.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGE04369.1 - 0.22 11.5 0.4 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding RNase_H PF00075.24 EGE04370.1 - 2.9e-23 82.6 0.0 4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGE04370.1 - 0.058 13.2 0.5 10 5.9 0.1 2.5 2 1 0 2 2 2 0 Reverse transcriptase-like YyzF PF14116.6 EGE04370.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 YyzF-like protein RNase_H PF00075.24 EGE04371.1 - 1e-21 77.6 0.6 1.4e-21 77.2 0.6 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGE04371.1 - 1.4e-06 28.1 5.1 0.00023 21.0 5.1 2.6 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 EGE04372.1 - 3.3e-11 43.5 0.0 5.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGE04372.1 - 0.043 13.6 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like TPT PF03151.16 EGE04374.1 - 1.2e-23 84.0 25.0 1.5e-23 83.5 25.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EGE04374.1 - 8.6e-05 21.9 23.9 0.00013 21.3 23.9 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGE04374.1 - 0.094 12.9 34.7 0.41 10.8 12.8 2.7 3 0 0 3 3 3 0 EamA-like transporter family TFIIB PF00382.19 EGE04376.1 - 1.3e-30 105.2 0.4 4.2e-17 62.0 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGE04376.1 - 1.4e-25 89.5 1.1 5.4e-25 87.7 0.0 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EGE04376.1 - 0.00012 21.5 2.7 0.00028 20.3 2.7 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EGE04376.1 - 0.012 15.4 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain zf-RRN7 PF11781.8 EGE04376.1 - 0.32 10.7 1.6 0.7 9.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Equine_IAV_S2 PF06502.11 EGE04377.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein E1-E2_ATPase PF00122.20 EGE04378.1 - 1.6e-50 171.2 0.1 5.2e-50 169.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EGE04378.1 - 9.3e-36 122.1 4.8 1.1e-09 38.6 0.4 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EGE04378.1 - 6.6e-34 118.0 0.2 1.2e-33 117.2 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE04378.1 - 3.6e-05 23.6 1.1 0.00099 18.9 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGE04378.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Borrelia_REV PF03978.13 EGE04378.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein ERCC4 PF02732.15 EGE04379.1 - 1.2e-25 90.5 0.1 1.9e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EGE04379.1 - 0.007 16.7 0.1 0.98 9.8 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain Zn_clus PF00172.18 EGE04380.1 - 1.5e-06 28.2 10.5 2.3e-06 27.6 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE04380.1 - 7.2e-05 21.9 0.1 0.00019 20.5 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRP3 PF08572.10 EGE04381.1 - 1.8e-74 250.3 2.9 2.9e-74 249.6 2.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGE04381.1 - 2.7e-48 163.8 0.5 2.7e-48 163.8 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 EGE04382.1 - 1.8e-88 296.4 0.0 3e-88 295.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGE04382.1 - 7e-67 224.8 0.1 1.5e-66 223.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGE04382.1 - 2.4e-34 118.5 0.0 6.2e-33 113.9 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGE04382.1 - 3.1e-27 95.7 3.2 6.7e-26 91.4 3.1 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGE04382.1 - 2e-17 63.1 0.0 7.4e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DEAD_2 PF06733.15 EGE04383.1 - 3.5e-56 189.6 0.1 7.6e-56 188.5 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EGE04383.1 - 2.5e-47 161.0 1.8 4.4e-42 143.9 0.6 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EGE04383.1 - 1.3e-32 113.3 0.1 2.9e-31 108.9 0.1 2.7 1 1 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EGE04383.1 - 5.8e-06 26.4 0.0 0.0009 19.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE04383.1 - 0.00037 20.3 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EGE04383.1 - 0.0066 15.2 0.1 0.19 10.4 0.1 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EGE04383.1 - 0.058 13.7 2.4 12 6.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGE04383.1 - 0.15 12.4 0.0 0.58 10.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGE04383.1 - 3.8 7.2 5.6 0.92 9.2 0.4 2.4 2 1 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 EGE04384.1 - 1.6e-07 31.5 11.7 3.7e-07 30.4 11.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EGE04384.1 - 0.00022 21.2 4.1 0.00051 20.0 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGE04384.1 - 0.00035 20.8 10.6 0.001 19.3 10.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Xpo1 PF08389.12 EGE04384.1 - 0.001 19.2 11.2 0.43 10.6 0.7 4.4 4 0 0 4 4 4 2 Exportin 1-like protein FANCL_C PF11793.8 EGE04384.1 - 0.0014 18.7 6.9 0.0032 17.6 6.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 EGE04384.1 - 0.0043 16.9 11.1 0.012 15.5 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE04384.1 - 0.0049 16.7 13.0 0.011 15.6 13.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGE04384.1 - 0.018 14.7 6.7 0.043 13.4 6.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2913 PF11140.8 EGE04384.1 - 0.087 12.6 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) DICT PF10069.9 EGE04384.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system zf-RING-like PF08746.11 EGE04384.1 - 0.21 12.0 10.1 0.54 10.6 10.1 1.8 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.22 EGE04384.1 - 1.1 9.2 8.6 0.4 10.6 5.6 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 EGE04384.1 - 1.5 9.0 10.1 3.4 7.9 10.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 EGE04384.1 - 4.6 7.1 5.5 12 5.8 5.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EGE04384.1 - 7.6 6.5 7.8 19 5.2 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LCM PF04072.14 EGE04385.1 - 5.4e-24 85.2 0.0 1.2e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.13 EGE04386.1 - 2.2e-78 263.1 10.7 3.2e-78 262.6 10.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Apt1 PF10351.9 EGE04386.1 - 0.98 8.2 12.6 1.3 7.8 12.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EGE04386.1 - 3.8 6.6 21.2 5.4 6.1 21.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EGE04386.1 - 8.7 4.9 13.2 12 4.5 13.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3HC4 PF00097.25 EGE04387.1 - 3.8e-09 36.3 6.9 8.7e-08 31.9 6.9 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE04387.1 - 1.4e-07 31.3 2.9 6e-07 29.3 2.9 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGE04387.1 - 6.3e-07 29.1 6.2 0.00018 21.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE04387.1 - 2.5e-06 27.4 1.8 2.5e-06 27.4 1.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGE04387.1 - 6.2e-06 26.0 8.7 1.3e-05 24.9 2.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE04387.1 - 4.7e-05 23.6 4.2 4.7e-05 23.6 4.2 3.3 4 0 0 4 4 2 1 Ring finger domain zf-CCCH_4 PF18044.1 EGE04387.1 - 5.2e-05 22.9 19.4 0.01 15.7 2.5 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger Prok-RING_4 PF14447.6 EGE04387.1 - 0.0022 17.8 6.9 0.19 11.6 2.5 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-CCCH PF00642.24 EGE04387.1 - 0.0025 17.7 16.0 0.021 14.7 1.5 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 PF12678.7 EGE04387.1 - 0.0048 17.2 9.3 0.065 13.5 4.0 2.9 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGE04387.1 - 0.0054 16.9 5.4 0.006 16.7 1.9 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGE04387.1 - 0.011 15.7 0.9 0.73 9.9 0.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger YyzF PF14116.6 EGE04387.1 - 0.012 15.7 0.3 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 YyzF-like protein Zn_ribbon_17 PF17120.5 EGE04387.1 - 0.013 15.1 0.7 0.013 15.1 0.7 2.6 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-CCCH_3 PF15663.5 EGE04387.1 - 0.092 13.0 3.6 0.23 11.7 0.2 2.9 4 0 0 4 4 4 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGE04387.1 - 0.16 12.5 20.0 1.1 9.8 3.6 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGE04387.1 - 0.17 12.6 10.9 0.29 11.8 0.7 3.3 2 2 0 2 2 2 0 Torus domain zf-RING_6 PF14835.6 EGE04387.1 - 0.55 10.1 5.2 0.26 11.2 2.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EGE04387.1 - 3.3 7.6 8.0 20 5.0 8.0 2.3 1 1 0 1 1 1 0 RING-like zinc finger DUF1180 PF06679.12 EGE04387.1 - 6.8 7.1 7.0 14 6.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Ist1 PF03398.14 EGE04388.1 - 5.9e-27 94.6 0.6 1.5e-14 54.3 1.8 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway SfLAP PF11139.8 EGE04389.1 - 0.0014 18.2 0.1 0.0036 16.8 0.1 1.7 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein Peptidase_S28 PF05577.12 EGE04391.1 - 4.5e-56 190.5 0.5 7.6e-56 189.7 0.5 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DAHP_synth_2 PF01474.16 EGE04393.1 - 1.6e-70 237.9 0.8 1.3e-48 165.7 0.1 2.0 2 0 0 2 2 2 2 Class-II DAHP synthetase family AMP-binding PF00501.28 EGE04396.1 - 3.6e-57 193.9 0.0 4.3e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE04396.1 - 0.0033 18.3 0.0 0.008 17.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Clat_adaptor_s PF01217.20 EGE04397.1 - 2.5e-32 111.7 0.4 3.3e-32 111.4 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1619 PF07773.11 EGE04397.1 - 0.12 12.3 0.3 0.89 9.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1619) Orbi_NS1 PF01718.16 EGE04398.1 - 0.028 12.9 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein TP_methylase PF00590.20 EGE04399.1 - 4.7e-23 82.2 0.2 7.4e-23 81.6 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 EGE04400.1 - 2.2e-30 104.5 0.4 2.4e-29 101.2 0.4 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.21 EGE04401.1 - 5.7e-63 213.3 0.0 6.8e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGE04401.1 - 0.032 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGE04401.1 - 0.048 12.2 0.2 0.088 11.3 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Tam41_Mmp37 PF09139.11 EGE04403.1 - 6.3e-132 439.9 0.0 7.8e-132 439.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 EGE04404.1 - 1.5e-43 147.3 8.7 4.5e-21 75.3 0.2 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain MPDZ_u10 PF16667.5 EGE04404.1 - 0.25 12.2 0.2 0.25 12.2 0.2 6.6 6 2 3 9 9 9 0 Unstructured region 10 on multiple PDZ protein zf-C2H2_jaz PF12171.8 EGE04405.1 - 2e-08 34.3 0.4 4e-08 33.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGE04405.1 - 9.3e-06 25.9 0.5 9.3e-06 25.9 0.5 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGE04405.1 - 0.0008 19.7 0.4 0.0016 18.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGE04405.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) AMP-binding PF00501.28 EGE04407.1 - 7.2e-42 143.4 0.0 1.1e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE04407.1 - 0.00076 20.4 0.0 0.0015 19.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb5_C PF01191.19 EGE04410.1 - 6.2e-27 93.3 0.2 1.1e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGE04410.1 - 5.2e-26 91.1 0.0 8.7e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGE04410.1 - 0.00051 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease DUF2968 PF11180.8 EGE04411.1 - 0.0002 21.0 8.5 0.0002 21.0 8.5 4.4 3 1 1 4 4 4 2 Protein of unknown function (DUF2968) Fib_alpha PF08702.10 EGE04411.1 - 0.0052 17.0 4.7 0.0052 17.0 4.7 4.6 2 1 2 4 4 4 2 Fibrinogen alpha/beta chain family DUF4363 PF14276.6 EGE04411.1 - 0.0061 16.7 5.2 0.0061 16.7 5.2 4.3 3 2 1 5 5 5 1 Domain of unknown function (DUF4363) APG6_N PF17675.1 EGE04411.1 - 0.019 15.5 18.0 0.019 15.5 18.0 4.6 2 1 1 4 4 4 0 Apg6 coiled-coil region Helicase_IV_N PF12462.8 EGE04411.1 - 0.029 14.3 0.3 0.029 14.3 0.3 3.2 3 1 0 3 3 3 0 DNA helicase IV / RNA helicase N terminal Spectrin PF00435.21 EGE04411.1 - 0.19 12.2 34.0 0.035 14.6 9.0 3.7 3 1 0 3 3 3 0 Spectrin repeat DUF1664 PF07889.12 EGE04411.1 - 2.5 8.1 21.9 0.98 9.5 3.1 4.1 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) PhoU PF01895.19 EGE04411.1 - 2.8 8.5 12.4 4 8.0 1.9 3.7 2 1 1 3 3 3 0 PhoU domain Baculo_PEP_C PF04513.12 EGE04411.1 - 8.6 6.4 16.3 1.6 8.8 3.4 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CYSTM PF12734.7 EGE04412.1 - 3.5e-14 52.8 12.9 3.5e-14 52.8 12.9 4.0 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EGE04412.1 - 0.37 11.4 8.8 0.48 11.1 8.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 EGE04412.1 - 0.73 9.8 16.6 1.2 9.2 16.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) ECF_trnsprt PF12822.7 EGE04413.1 - 0.023 14.8 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component Methyltr_RsmB-F PF01189.17 EGE04414.1 - 3e-29 102.1 0.0 2.5e-22 79.5 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 EGE04414.1 - 0.2 11.0 0.0 0.82 9.0 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Abhydrolase_3 PF07859.13 EGE04415.1 - 2.7e-32 112.4 0.0 6e-32 111.2 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGE04415.1 - 0.057 13.5 0.0 0.085 13.0 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain PLAC8 PF04749.17 EGE04417.1 - 1.3e-16 61.4 11.3 1.6e-16 61.1 11.3 1.1 1 0 0 1 1 1 1 PLAC8 family Aldolase_II PF00596.21 EGE04418.1 - 5.7e-45 153.5 0.1 7.3e-45 153.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.29 EGE04419.1 - 2.2e-43 148.0 0.1 3.3e-43 147.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE04419.1 - 9.1e-19 67.8 0.2 4.6e-18 65.6 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE04419.1 - 0.00028 20.9 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RIP PF00161.19 EGE04419.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosome inactivating protein Ank_2 PF12796.7 EGE04420.1 - 3.3e-30 104.5 21.2 2.9e-06 27.8 0.0 12.4 8 4 3 12 12 12 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE04420.1 - 2e-21 76.1 19.8 0.017 15.7 0.0 14.3 11 2 2 13 13 13 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE04420.1 - 9.4e-13 48.1 2.6 0.49 10.8 0.0 9.7 10 1 1 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04420.1 - 1.1e-12 46.9 14.0 11 7.0 0.0 16.2 20 0 0 20 20 20 2 Ankyrin repeat Ank PF00023.30 EGE04420.1 - 6.9e-08 32.6 33.5 3.7 8.2 0.0 15.1 18 3 1 19 19 19 2 Ankyrin repeat Polysacc_deac_1 PF01522.21 EGE04420.1 - 0.056 13.4 0.1 0.86 9.5 0.1 2.7 3 0 0 3 3 3 0 Polysaccharide deacetylase NigD_C PF17415.2 EGE04420.1 - 0.13 12.3 0.0 0.49 10.5 0.0 1.9 1 0 0 1 1 1 0 NigD-like C-terminal beta sandwich domain Adenylsucc_synt PF00709.21 EGE04421.1 - 3.4e-163 543.4 0.0 3.8e-163 543.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.31 EGE04422.1 - 3e-22 78.5 1.1 6e-22 77.5 1.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1672 PF07901.11 EGE04422.1 - 0.14 11.4 1.5 0.25 10.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Fungal_trans PF04082.18 EGE04423.1 - 6.9e-23 81.0 0.0 2.2e-22 79.4 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE04423.1 - 3.8e-08 33.3 13.3 6.2e-08 32.6 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 EGE04424.1 - 5.4e-16 58.2 0.8 1.4e-15 56.9 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EGE04424.1 - 0.00015 21.5 0.1 0.00052 19.8 0.1 2.0 2 0 0 2 2 2 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 EGE04424.1 - 0.00016 21.7 0.0 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.26 EGE04424.1 - 0.00048 20.4 20.1 0.072 13.6 1.6 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE04424.1 - 0.00075 20.1 1.5 0.00075 20.1 1.5 5.4 6 0 0 6 6 6 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE04424.1 - 0.63 10.6 9.5 3.4 8.2 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 EGE04424.1 - 1.1 9.9 6.3 1 10.0 0.3 2.9 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Cupin_8 PF13621.6 EGE04425.1 - 7.7e-33 114.3 0.0 1.6e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGE04425.1 - 1.5e-06 27.9 0.0 0.0011 18.6 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EGE04425.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EGE04425.1 - 0.095 12.4 0.0 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Cupin domain 2OG-FeII_Oxy_2 PF13532.6 EGE04426.1 - 4.1e-36 125.0 0.2 6.9e-36 124.3 0.2 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.16 EGE04426.1 - 4.5e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain zf-GRF PF06839.12 EGE04426.1 - 0.00019 21.4 7.9 0.0004 20.4 7.9 1.5 1 0 0 1 1 1 1 GRF zinc finger POTRA_3 PF17287.2 EGE04426.1 - 0.12 11.8 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 POTRA domain VWA PF00092.28 EGE04427.1 - 0.01 16.1 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain FH2 PF02181.23 EGE04427.1 - 0.28 10.3 0.0 0.45 9.6 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain UQ_con PF00179.26 EGE04428.1 - 2.9e-07 30.2 0.3 5.9e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGE04428.1 - 0.14 12.4 0.2 0.31 11.3 0.2 1.5 1 0 0 1 1 1 0 RWD domain DUF5314 PF17241.2 EGE04428.1 - 0.22 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5314) GTP1_OBG PF01018.22 EGE04429.1 - 5.9e-37 126.7 2.0 4.1e-27 94.7 3.3 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EGE04429.1 - 1e-22 80.4 0.0 2e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE04429.1 - 7.2e-08 32.1 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EGE04429.1 - 0.012 14.7 0.0 0.51 9.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGE04429.1 - 0.099 13.2 2.0 0.15 12.6 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Peptidase_M16_M PF16187.5 EGE04430.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 1 0 1 1 1 0 Middle or third domain of peptidase_M16 Mis12 PF05859.12 EGE04430.1 - 0.13 12.3 0.1 0.33 11.0 0.0 1.8 1 1 1 2 2 2 0 Mis12 protein MFS_1 PF07690.16 EGE04433.1 - 1.3e-35 123.0 11.5 4.6e-34 117.9 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04433.1 - 9e-10 38.0 1.9 2e-09 36.8 1.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter Abhydrolase_6 PF12697.7 EGE04434.1 - 7.7e-16 59.4 5.8 4.2e-15 56.9 5.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE04434.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.32 EGE04435.1 - 1.6e-09 38.2 7.4 0.0058 17.4 0.2 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Ccdc124 PF06244.12 EGE04436.1 - 9.6e-28 97.3 26.4 9.6e-28 97.3 26.4 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 F-box-like PF12937.7 EGE04437.1 - 4.6e-07 29.6 0.3 9.2e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE04437.1 - 1.8e-06 27.7 0.6 1.8e-06 27.7 0.6 2.8 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 EGE04437.1 - 0.0018 18.1 0.1 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box Peptidase_C13 PF01650.18 EGE04438.1 - 5.2e-41 140.9 0.0 8.4e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.14 EGE04439.1 - 3.5e-239 795.4 0.0 2.2e-238 792.7 0.0 2.6 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 EGE04439.1 - 0.13 11.6 26.2 0.19 11.0 10.8 2.1 2 0 0 2 2 2 0 BUD22 FAM60A PF15396.6 EGE04439.1 - 0.87 9.6 5.3 0.18 11.8 1.3 1.8 2 0 0 2 2 2 0 Protein Family FAM60A CSRNP_N PF16019.5 EGE04439.1 - 2.9 7.7 6.1 6.4 6.6 6.1 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Med5 PF08689.10 EGE04439.1 - 4.5 5.0 4.9 6.3 4.5 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 Acetyltransf_7 PF13508.7 EGE04440.1 - 6.6e-09 36.1 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGE04440.1 - 1.9e-08 34.3 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE04440.1 - 2.1e-07 31.2 0.0 4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGE04440.1 - 2.4e-05 24.2 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGE04440.1 - 0.0032 17.6 0.5 0.34 11.0 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 EGE04443.1 - 2.8e-40 138.4 48.3 3.8e-40 138.0 48.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE04443.1 - 8.2e-22 77.4 44.1 5.4e-21 74.7 44.1 1.8 1 1 0 1 1 1 1 Amino acid permease YlaH PF14036.6 EGE04443.1 - 0.0002 21.6 1.7 0.00096 19.4 1.7 2.2 1 0 0 1 1 1 1 YlaH-like protein CBM_19 PF03427.13 EGE04443.1 - 0.082 12.9 0.6 0.24 11.4 0.6 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Acetyltransf_3 PF13302.7 EGE04444.1 - 4.9e-17 62.9 0.0 8.8e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE04444.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGE04444.1 - 0.00021 21.2 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGE04444.1 - 0.062 13.2 0.0 0.47 10.4 0.0 2.0 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EGE04445.1 - 0.00017 21.6 8.3 0.00034 20.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 EGE04446.1 - 1.7e-140 468.9 0.0 2e-140 468.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.20 EGE04449.1 - 1.4e-159 531.6 4.7 2e-159 531.0 4.7 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EGE04449.1 - 6.9e-24 83.5 0.1 1.4e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EGE04449.1 - 1.4e-14 54.3 0.0 5.5e-14 52.4 0.0 2.1 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 EGE04449.1 - 0.12 12.6 0.2 0.32 11.2 0.2 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Utp11 PF03998.13 EGE04450.1 - 2.8e-57 194.5 28.8 3.2e-57 194.3 28.8 1.0 1 0 0 1 1 1 1 Utp11 protein GCIP PF13324.6 EGE04450.1 - 0.6 9.7 6.5 0.83 9.2 6.5 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cmc1 PF08583.10 EGE04451.1 - 5.5e-12 45.5 4.1 1.5e-11 44.2 4.1 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like TFIID-31kDa PF02291.15 EGE04452.1 - 5.6e-45 152.4 0.0 7.5e-45 151.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 EGE04453.1 - 4.8e-95 317.3 0.0 6.8e-95 316.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGE04453.1 - 7.2e-43 144.7 0.0 1.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EGE04453.1 - 0.026 14.1 0.0 0.26 10.8 0.0 2.5 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EGE04454.1 - 0.00063 20.0 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF4407 PF14362.6 EGE04454.1 - 0.34 10.2 27.8 0.15 11.4 24.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 EGE04454.1 - 1.4 9.4 26.7 3.4 8.2 2.4 3.4 2 1 1 3 3 3 0 Snapin/Pallidin T3SSipB PF16535.5 EGE04454.1 - 2.2 8.7 16.9 1.4 9.3 14.1 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB Leu_zip PF15294.6 EGE04454.1 - 7 6.1 33.7 3 7.3 30.7 1.7 1 1 1 2 2 2 0 Leucine zipper Thg1 PF04446.12 EGE04455.1 - 8.5e-55 184.1 0.1 1.4e-54 183.4 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGE04455.1 - 5e-51 172.0 2.8 6.8e-51 171.5 2.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain RNA_pol_Rpb1_1 PF04997.12 EGE04457.1 - 3.3e-112 374.9 0.0 6e-112 374.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGE04457.1 - 2.4e-74 249.1 0.0 5.9e-74 247.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 EGE04457.1 - 3.3e-74 249.7 0.0 2.6e-39 135.3 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 EGE04457.1 - 2.3e-65 220.0 1.4 4.4e-65 219.1 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGE04457.1 - 7.3e-47 159.2 0.0 1.7e-46 158.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGE04457.1 - 1.7e-44 151.1 7.7 2.6e-44 150.5 5.8 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGE04457.1 - 7.3e-38 128.8 0.2 1.6e-37 127.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGE04457.1 - 4.4e-17 61.4 200.0 0.01 16.1 1.4 14.0 12 1 1 13 13 13 10 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 EGE04458.1 - 6.9e-16 58.3 10.5 2.4e-06 28.2 0.5 5.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04458.1 - 3.4e-11 43.3 1.3 0.006 16.9 0.0 4.3 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE04458.1 - 8.3e-05 22.6 0.1 0.78 9.6 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGE04458.1 - 0.11 10.9 0.0 0.21 10.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Methyltransf_23 PF13489.6 EGE04459.1 - 1.2e-16 61.0 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04459.1 - 1.3e-08 35.4 0.0 4.5e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE04459.1 - 1.7e-05 25.3 0.0 6.5e-05 23.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE04459.1 - 4.8e-05 23.2 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE04459.1 - 0.0002 20.9 0.0 0.00047 19.7 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.12 EGE04459.1 - 0.00036 21.2 0.0 0.0012 19.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE04459.1 - 0.00096 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGE04459.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EGE04459.1 - 0.0061 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EGE04459.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EGE04459.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 EGE04459.1 - 0.086 12.1 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGE04459.1 - 0.11 11.8 0.0 0.57 9.5 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family BDV_P10 PF06515.11 EGE04460.1 - 0.011 15.8 0.1 0.022 14.8 0.1 1.5 1 1 0 1 1 1 0 Borna disease virus P10 protein ALG11_N PF15924.5 EGE04462.1 - 8.3e-83 277.5 0.0 1.1e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGE04462.1 - 1.6e-18 66.9 0.0 4.1e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGE04462.1 - 2.5e-07 31.2 0.0 2.9e-06 27.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGE04462.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 HemY_N PF07219.13 EGE04462.1 - 0.026 14.7 0.4 0.073 13.3 0.4 1.7 1 0 0 1 1 1 0 HemY protein N-terminus 60KD_IMP PF02096.20 EGE04463.1 - 4.3e-14 52.7 0.4 5.3e-14 52.5 0.4 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Antimicrobial19 PF08225.11 EGE04463.1 - 0.16 11.6 1.9 1.6 8.4 0.2 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide PP2C PF00481.21 EGE04464.1 - 1.8e-41 142.5 0.0 2.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGE04464.1 - 0.0003 20.5 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGE04464.1 - 0.025 14.5 0.0 0.67 9.8 0.0 2.6 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PPDFL PF15060.6 EGE04464.1 - 1.4 9.5 7.3 9.6 6.8 0.0 2.9 2 1 0 2 2 2 0 Differentiation and proliferation regulator Tcf25 PF04910.14 EGE04465.1 - 1.5e-62 211.8 0.1 1.2e-43 149.5 0.0 2.2 1 1 1 2 2 2 2 Transcriptional repressor TCF25 DUF1754 PF08555.10 EGE04465.1 - 0.025 15.4 3.1 0.025 15.4 3.1 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1387 PF07139.11 EGE04465.1 - 0.22 11.2 7.3 0.16 11.7 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Stm1_N PF09598.10 EGE04465.1 - 0.6 11.0 9.2 3 8.7 9.2 2.3 1 1 0 1 1 1 0 Stm1 DUF3381 PF11861.8 EGE04465.1 - 2.4 7.9 7.7 4.1 7.2 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PQ-loop PF04193.14 EGE04466.1 - 1.7e-39 133.4 4.7 8.9e-20 70.2 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_60s PF00428.19 EGE04467.1 - 1.4e-20 73.7 6.9 2.1e-20 73.1 6.9 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 EGE04468.1 - 4.1e-50 169.8 0.1 2.5e-28 99.3 0.0 5.2 4 2 1 5 5 5 4 Protein of unknown function (DUF2408) CARD PF00619.21 EGE04468.1 - 0.034 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain PolyG_pol PF01518.16 EGE04468.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma NS protein Baculo_PEP_C PF04513.12 EGE04468.1 - 0.13 12.3 0.6 0.85 9.6 0.1 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EGE04468.1 - 0.14 12.6 1.3 3.1 8.3 0.1 3.2 3 0 0 3 3 3 0 Snapin/Pallidin ATG16 PF08614.11 EGE04468.1 - 0.56 10.4 2.1 9 6.5 0.0 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Aconitase PF00330.20 EGE04469.1 - 8.8e-144 479.9 0.0 1.2e-143 479.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGE04469.1 - 3.6e-41 140.6 0.0 5.8e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Importin_rep_4 PF18808.1 EGE04470.1 - 2.1e-33 114.4 2.8 7.8e-33 112.6 1.1 3.0 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 EGE04470.1 - 4.7e-20 71.7 11.2 1.2e-08 35.3 0.3 8.4 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 EGE04470.1 - 5.9e-20 71.4 4.2 0.0005 20.4 0.0 7.7 5 2 3 8 8 7 6 HEAT repeats HEAT PF02985.22 EGE04470.1 - 4.1e-16 57.7 11.1 0.0067 16.6 0.0 11.0 13 0 0 13 13 9 4 HEAT repeat Importin_rep_6 PF18829.1 EGE04470.1 - 4.2e-14 52.6 0.8 2.8e-13 50.0 0.2 2.7 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EGE04470.1 - 9.6e-10 38.9 0.0 0.087 13.4 0.0 5.9 3 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EGE04470.1 - 3.9e-08 32.8 0.4 0.00012 21.3 0.1 4.2 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGE04470.1 - 1.6e-07 31.4 0.4 0.21 11.5 0.0 5.4 5 2 0 6 6 6 2 Domain of unknown function (DUF3385) Cnd1 PF12717.7 EGE04470.1 - 3e-06 27.3 0.0 0.025 14.6 0.0 3.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Importin_rep_5 PF18816.1 EGE04470.1 - 3.7e-06 27.1 1.8 1.3e-05 25.4 1.8 2.0 1 0 0 1 1 1 1 Importin repeat RIX1 PF08167.12 EGE04470.1 - 8.9e-06 25.6 0.3 0.0011 18.7 0.0 4.1 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.23 EGE04470.1 - 9e-06 25.6 0.6 1.2 9.2 0.1 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGE04470.1 - 2.3e-05 24.1 0.0 0.2 11.2 0.0 5.0 5 1 0 5 5 5 1 CLASP N terminal DRIM PF07539.12 EGE04470.1 - 0.0001 20.8 0.7 0.028 12.7 0.1 3.4 2 2 1 3 3 3 1 Down-regulated in metastasis RTP1_C1 PF10363.9 EGE04470.1 - 0.00025 21.2 0.1 0.2 11.9 0.1 3.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EGE04470.1 - 0.0009 17.9 0.3 0.018 13.6 0.1 2.9 2 1 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.19 EGE04470.1 - 0.0022 17.9 1.2 0.032 14.1 0.0 3.6 4 0 0 4 4 3 1 Importin-beta N-terminal domain Cnd3 PF12719.7 EGE04470.1 - 0.023 13.9 0.3 3.5 6.7 0.0 3.8 2 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain V-ATPase_H_N PF03224.14 EGE04470.1 - 0.026 13.8 0.9 0.12 11.6 0.0 2.5 3 0 0 3 3 3 0 V-ATPase subunit H DUF4042 PF13251.6 EGE04470.1 - 0.25 11.0 2.3 15 5.2 0.0 4.2 6 0 0 6 6 5 0 Domain of unknown function (DUF4042) CBS PF00571.28 EGE04471.1 - 6e-35 119.5 6.4 1.1e-08 35.4 0.1 5.5 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EGE04471.1 - 8e-08 32.1 0.9 1.8e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.19 EGE04472.1 - 4.7e-51 171.7 8.2 6e-51 171.4 8.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EGE04472.1 - 0.021 14.8 0.7 0.041 13.8 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EGE04472.1 - 0.2 11.5 1.9 0.26 11.1 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) F-box-like PF12937.7 EGE04473.1 - 0.0014 18.5 0.3 0.0046 16.8 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EGE04473.1 - 0.024 14.7 9.3 3.6 7.9 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Deltaretro_Tax PF05599.11 EGE04473.1 - 0.047 14.2 1.1 0.12 12.9 1.1 1.7 1 0 0 1 1 1 0 Deltaretrovirus Tax protein LRR_4 PF12799.7 EGE04473.1 - 0.49 10.9 15.9 0.91 10.0 0.2 5.2 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGE04473.1 - 3.8 8.4 7.7 64 4.7 0.2 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat Peptidase_C14 PF00656.22 EGE04475.1 - 2.2e-36 126.1 0.0 3e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EGE04475.1 - 0.24 11.3 0.6 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.24 EGE04476.1 - 9.2e-155 516.0 5.7 1.1e-154 515.8 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 EGE04476.1 - 0.036 14.5 0.1 13 6.3 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain DUF3994 PF13159.6 EGE04476.1 - 0.092 13.3 0.2 1.1 9.8 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3994) zf-H2C2 PF09337.10 EGE04477.1 - 1.5e-14 53.9 2.2 3.4e-14 52.8 2.2 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EGE04477.1 - 9e-10 38.5 0.5 9e-10 38.5 0.5 2.4 3 0 0 3 3 3 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EGE04477.1 - 0.00036 20.8 0.0 0.00096 19.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EGE04477.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGE04477.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribo_biogen_C PF04034.13 EGE04478.1 - 6.8e-51 171.3 0.0 9.3e-51 170.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGE04478.1 - 2.3e-09 36.9 0.4 3.7e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Peptidase_C37 PF05416.12 EGE04478.1 - 0.011 14.3 3.2 0.016 13.7 3.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase BUD22 PF09073.10 EGE04478.1 - 0.19 11.1 12.0 0.25 10.6 12.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGE04478.1 - 7.7 4.7 9.6 10 4.2 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein VHS PF00790.19 EGE04481.1 - 1.3e-44 151.5 0.0 6.5e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EGE04481.1 - 1.3e-20 73.4 0.8 1.3e-20 73.4 0.8 3.3 4 0 0 4 4 4 1 GAT domain Alpha_adaptinC2 PF02883.20 EGE04481.1 - 4.2e-18 65.7 0.2 4.2e-18 65.7 0.2 2.3 1 1 1 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EGE04481.1 - 2.3e-07 30.3 1.7 1.1e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 GGA N-GAT domain MCM PF00493.23 EGE04483.1 - 1.1e-97 325.6 0.0 1.8e-97 324.8 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGE04483.1 - 2.5e-39 134.0 0.1 4.6e-39 133.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EGE04483.1 - 1.1e-26 94.0 28.6 1.1e-26 94.0 28.6 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EGE04483.1 - 3.1e-24 85.2 0.3 1e-23 83.5 0.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGE04483.1 - 8.1e-12 45.7 0.2 2.5e-11 44.1 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE04483.1 - 1.4e-07 31.2 0.1 7.7e-06 25.4 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE04483.1 - 2.7e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGE04483.1 - 0.0012 18.7 0.0 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGE04483.1 - 0.0055 16.4 0.2 0.085 12.6 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGE04483.1 - 0.16 11.7 0.3 0.35 10.6 0.3 1.5 1 0 0 1 1 1 0 AAA domain zf-UBR PF02207.20 EGE04484.1 - 4.4e-14 52.4 4.1 4.4e-14 52.4 4.1 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Pkinase PF00069.25 EGE04485.1 - 4.5e-64 216.3 0.0 5.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04485.1 - 5.7e-30 104.5 0.0 8.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE04485.1 - 0.0046 15.9 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain ADH_zinc_N PF00107.26 EGE04486.1 - 4.5e-09 36.4 0.0 7.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE04486.1 - 0.14 13.2 0.0 0.28 12.2 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase UvdE PF03851.14 EGE04488.1 - 4.2e-109 364.0 0.0 5.3e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Condensation PF00668.20 EGE04489.1 - 1.1e-48 166.1 0.0 1.8e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EGE04489.1 - 4.2e-46 157.4 0.8 1.4e-24 86.5 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme Acyl_transf_1 PF00698.21 EGE04489.1 - 1.4e-42 146.4 0.0 2.5e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EGE04489.1 - 3e-41 141.6 0.0 4.8e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGE04489.1 - 8.5e-37 126.8 0.0 7.4e-35 120.5 0.0 2.5 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 EGE04489.1 - 8.5e-29 100.9 0.0 1.8e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGE04489.1 - 6.8e-24 84.4 0.0 2.2e-22 79.5 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGE04489.1 - 1.3e-21 76.8 0.0 3.7e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EGE04489.1 - 5e-18 65.2 0.2 5.7e-08 33.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EGE04489.1 - 1e-17 64.7 0.0 3.3e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04489.1 - 2.5e-11 44.1 0.0 1e-10 42.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE04489.1 - 3.7e-09 36.6 0.0 7.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGE04489.1 - 4.2e-09 36.8 0.0 2.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_31 PF13847.6 EGE04489.1 - 2.4e-08 33.9 0.0 9e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE04489.1 - 4.6e-08 33.6 0.0 1.5e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EGE04489.1 - 4.2e-07 29.7 0.0 8.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 EGE04489.1 - 1.6e-05 24.3 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGE04489.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_33 PF10017.9 EGE04489.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent AMP-binding_C PF13193.6 EGE04489.1 - 0.02 15.9 0.1 0.094 13.7 0.0 2.3 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain Post_transc_reg PF13797.6 EGE04489.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Post-transcriptional regulator Sugar_tr PF00083.24 EGE04490.1 - 5.7e-86 289.2 24.2 1e-85 288.3 24.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE04490.1 - 6.5e-33 114.1 42.9 1.2e-23 83.7 10.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGE04490.1 - 6.8e-06 25.6 4.8 6.8e-06 25.6 4.8 3.0 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGE04490.1 - 0.0051 15.2 2.0 0.0051 15.2 2.0 2.0 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MIS13 PF08202.11 EGE04491.1 - 2.3e-43 148.6 4.7 2.3e-43 148.6 4.7 2.8 2 1 0 2 2 2 1 Mis12-Mtw1 protein family GGN PF15685.5 EGE04491.1 - 1.5e-05 24.3 3.5 1.5e-05 24.3 3.5 2.2 2 0 0 2 2 2 1 Gametogenetin DivIC PF04977.15 EGE04491.1 - 0.018 14.8 0.1 0.054 13.3 0.1 1.8 1 0 0 1 1 1 0 Septum formation initiator RPN7 PF10602.9 EGE04492.1 - 7.9e-55 185.2 0.5 1.5e-54 184.4 0.5 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGE04492.1 - 8.3e-12 45.6 0.0 1.8e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 EGE04492.1 - 0.11 12.5 2.0 0.51 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 EGE04493.1 - 1.7e-38 132.8 0.0 2.2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TetR_C_14 PF17754.1 EGE04493.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 MftR C-terminal domain PEPCK_ATP PF01293.20 EGE04495.1 - 2.5e-217 722.1 0.0 3e-217 721.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MGAT2 PF05060.14 EGE04496.1 - 0.1 11.6 0.7 0.12 11.4 0.7 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Sugar_tr PF00083.24 EGE04497.1 - 1.5e-20 73.5 19.5 6.5e-12 45.0 8.5 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGE04497.1 - 2.2e-09 36.7 56.5 3.2e-08 32.9 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.14 EGE04498.1 - 5.8e-69 232.0 0.1 6.5e-69 231.8 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Amidase PF01425.21 EGE04499.1 - 2.3e-67 227.9 0.4 1.7e-65 221.8 0.3 2.0 1 1 1 2 2 2 2 Amidase ARID PF01388.21 EGE04500.1 - 3.5e-11 43.6 0.0 4.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3328 PF11807.8 EGE04501.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RFX_DNA_binding PF02257.15 EGE04501.1 - 0.11 13.1 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain DJ-1_PfpI PF01965.24 EGE04502.1 - 1.2e-16 61.0 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GPI-anchored PF10342.9 EGE04503.1 - 1.4e-11 45.0 0.1 6.2e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ArfGap PF01412.18 EGE04504.1 - 1.1e-39 135.1 2.5 1.9e-39 134.4 2.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SelR PF01641.18 EGE04505.1 - 1e-50 170.8 0.2 1.2e-50 170.6 0.2 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EGE04505.1 - 0.019 14.7 0.2 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 EGE04505.1 - 0.028 14.6 1.4 0.12 12.6 1.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 EGE04505.1 - 0.38 10.8 3.8 7 6.8 3.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon DUF1771 PF08590.10 EGE04506.1 - 2.2e-11 43.9 5.0 4.7e-11 42.9 5.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EGE04506.1 - 1.7e-06 27.6 0.0 2.2e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 CUE domain Smr PF01713.21 EGE04506.1 - 1.3e-05 25.4 0.2 3.3e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 Smr domain TMF_DNA_bd PF12329.8 EGE04506.1 - 0.75 9.8 2.6 1.2 9.1 0.1 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding EF_assoc_2 PF08356.12 EGE04507.1 - 1.1e-34 118.3 0.0 2.1e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EGE04507.1 - 2.3e-30 104.0 0.5 4.4e-30 103.1 0.5 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EGE04507.1 - 7e-24 84.2 0.0 1.2e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGE04507.1 - 3.8e-14 52.9 0.0 3.2e-08 33.8 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGE04507.1 - 3.2e-09 36.9 0.0 5.2e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 EGE04507.1 - 1.9e-07 30.4 0.3 0.025 14.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGE04507.1 - 7.1e-07 28.3 3.5 0.0071 15.8 0.1 2.9 3 0 0 3 3 2 2 EF hand EF-hand_7 PF13499.6 EGE04507.1 - 1.4e-06 28.6 1.1 0.004 17.6 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain pair AAA_16 PF13191.6 EGE04507.1 - 7.7e-06 26.4 0.3 0.054 13.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGE04507.1 - 3.1e-05 23.6 0.1 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_10 PF14788.6 EGE04507.1 - 4.3e-05 23.3 2.3 0.0072 16.2 0.3 2.4 2 0 0 2 2 2 1 EF hand Dynamin_N PF00350.23 EGE04507.1 - 0.00021 21.4 2.1 1.2 9.1 0.0 3.9 5 0 0 5 5 4 2 Dynamin family AAA_22 PF13401.6 EGE04507.1 - 0.00043 20.6 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGE04507.1 - 0.0016 18.4 0.1 2.4 8.1 0.1 3.4 3 0 0 3 3 3 1 RsgA GTPase Viral_helicase1 PF01443.18 EGE04507.1 - 0.0042 16.9 0.1 0.14 11.9 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGE04507.1 - 0.0065 17.0 0.5 2.6 8.6 0.2 3.1 3 0 0 3 3 2 1 AAA domain EF-hand_8 PF13833.6 EGE04507.1 - 0.0076 16.1 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair AAA_28 PF13521.6 EGE04507.1 - 0.0079 16.4 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGE04507.1 - 0.0081 16.5 0.1 1.3 9.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Septin PF00735.18 EGE04507.1 - 0.0084 15.4 0.2 1.1 8.5 0.1 3.0 3 0 0 3 3 3 1 Septin Ploopntkinase3 PF18751.1 EGE04507.1 - 0.0095 15.9 0.0 0.9 9.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 EGE04507.1 - 0.011 15.7 0.1 5.9 6.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.27 EGE04507.1 - 0.012 15.1 0.0 15 5.1 0.0 3.5 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGE04507.1 - 0.012 16.1 0.3 9.3 6.8 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 EGE04507.1 - 0.02 14.5 0.1 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGE04507.1 - 0.037 13.4 0.3 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EGE04507.1 - 0.039 13.7 0.1 0.67 9.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EGE04507.1 - 0.049 12.7 0.0 2.1 7.4 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain ATP_bind_1 PF03029.17 EGE04507.1 - 0.062 13.1 4.0 4 7.2 0.0 3.9 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGE04507.1 - 0.064 12.8 0.1 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGE04507.1 - 0.073 13.2 2.2 5.1 7.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EGE04507.1 - 0.11 11.8 0.1 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.14 EGE04507.1 - 0.11 12.5 0.3 32 4.5 0.0 3.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGE04507.1 - 0.12 11.5 0.2 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_5 PF13202.6 EGE04507.1 - 0.17 11.4 6.1 1.1 8.9 0.3 2.9 3 0 0 3 3 2 0 EF hand SMC_N PF02463.19 EGE04507.1 - 0.42 10.0 3.6 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGE04507.1 - 0.79 10.2 2.5 21 5.6 0.2 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Ysc84 PF04366.12 EGE04508.1 - 8.6e-43 145.1 0.3 1.8e-42 144.1 0.3 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EGE04508.1 - 2.4e-11 43.1 0.1 1.2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EGE04508.1 - 1.4e-10 40.7 0.0 3.4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGE04508.1 - 2.9e-10 39.8 0.0 4.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Zds_C PF08632.10 EGE04509.1 - 1.7e-28 98.1 3.4 1.9e-28 97.9 1.6 2.0 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term ArAE_2_N PF10337.9 EGE04510.1 - 2.6e-21 76.2 0.5 2.6e-21 76.2 0.5 3.3 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EGE04510.1 - 8.8e-12 45.3 12.0 8.8e-12 45.3 12.0 3.6 4 1 0 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EGE04510.1 - 2.6e-09 37.3 0.3 7.8e-08 32.4 0.0 2.9 3 0 0 3 3 3 1 Aromatic acid exporter family member 2 ANAPC4_WD40 PF12894.7 EGE04512.1 - 5.2e-13 49.1 0.0 2.3e-05 24.6 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE04512.1 - 9e-12 45.3 14.4 0.00013 22.7 0.3 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 EGE04512.1 - 0.00025 21.0 0.0 0.006 16.5 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGE04512.1 - 0.00091 17.4 0.0 0.0028 15.7 0.0 1.6 1 1 1 2 2 2 1 IKI3 family Vps16_N PF04841.13 EGE04512.1 - 0.0075 15.1 0.0 1.2 7.9 0.0 2.0 1 1 1 2 2 2 2 Vps16, N-terminal region Nup160 PF11715.8 EGE04512.1 - 0.014 14.1 0.1 0.019 13.6 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lgl_C PF08596.10 EGE04512.1 - 0.028 13.1 0.0 0.041 12.6 0.0 1.3 1 1 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal Cytochrom_D1 PF02239.16 EGE04512.1 - 0.034 12.7 0.0 0.087 11.3 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain Utp8 PF10395.9 EGE04512.1 - 0.034 12.7 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Utp8 family YpsA PF06908.11 EGE04512.1 - 0.054 13.5 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Importin_rep_6 PF18829.1 EGE04513.1 - 0.063 13.4 1.9 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Importin repeat 6 DUF4239 PF14023.6 EGE04513.1 - 0.52 10.0 1.7 1.3 8.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) KfrA_N PF11740.8 EGE04513.1 - 1.2 9.8 6.8 2.9 8.6 0.7 3.7 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term IZUMO PF15005.6 EGE04513.1 - 3.3 8.2 5.8 0.83 10.2 1.4 2.2 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated dCMP_cyt_deam_1 PF00383.23 EGE04514.1 - 0.00011 22.1 0.0 0.00035 20.4 0.0 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4819 PF16090.5 EGE04514.1 - 0.063 13.4 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4819) Cyclin PF08613.11 EGE04515.1 - 1.6e-29 103.3 1.8 1.6e-29 103.3 1.8 3.6 3 2 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGE04515.1 - 0.00049 19.8 0.0 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Arm PF00514.23 EGE04516.1 - 2.3e-08 33.8 13.9 0.0079 16.2 0.5 7.8 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat Fructosamin_kin PF03881.14 EGE04517.1 - 3.1e-72 243.2 0.0 4.5e-71 239.4 0.0 2.0 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGE04517.1 - 0.00052 20.0 0.0 0.001 19.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE04517.1 - 0.22 10.3 0.0 1.2 7.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) GST_N_2 PF13409.6 EGE04518.1 - 5e-15 55.6 0.0 9.3e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE04518.1 - 6e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGE04518.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE04518.1 - 0.035 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGE04518.1 - 0.048 14.2 0.0 0.079 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE04518.1 - 0.062 14.0 0.0 0.14 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain zf-C2H2_jaz PF12171.8 EGE04519.1 - 5.7e-08 32.8 51.5 0.053 13.8 0.3 9.9 7 3 3 10 10 10 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGE04519.1 - 3.6e-07 30.5 49.5 0.14 13.0 0.0 10.6 11 0 0 11 11 11 5 C2H2-type zinc finger zf-met PF12874.7 EGE04519.1 - 7.9e-05 22.9 44.0 0.067 13.6 0.5 8.8 8 1 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGE04519.1 - 0.00025 21.3 54.5 0.0079 16.6 0.2 10.5 9 1 1 10 10 10 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGE04519.1 - 0.0019 18.1 0.2 0.0019 18.1 0.2 7.0 9 0 0 9 9 9 1 C2H2-type zinc finger FOXP-CC PF16159.5 EGE04519.1 - 4.8 7.9 28.9 1.5 9.5 5.2 6.3 4 2 3 7 7 7 0 FOXP coiled-coil domain Zn-C2H2_12 PF18112.1 EGE04519.1 - 7.2 7.2 15.3 3.5 8.2 2.4 4.3 5 0 0 5 5 5 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 EGE04519.1 - 7.8 6.9 54.9 7.1 7.0 8.5 6.9 3 2 3 7 7 7 0 C2H2 type zinc-finger (2 copies) Cyclin_N PF00134.23 EGE04520.1 - 3.9e-09 36.3 0.0 1.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain MRP-S34 PF16053.5 EGE04520.1 - 0.0034 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CTP_transf_1 PF01148.20 EGE04521.1 - 9.4e-82 274.7 21.8 1.2e-81 274.4 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 EGE04522.1 - 4.9e-44 149.8 0.0 1.1e-43 148.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF1192 PF06698.11 EGE04522.1 - 0.012 15.6 3.9 0.044 13.8 3.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Takusan PF04822.13 EGE04522.1 - 0.02 14.8 0.5 0.02 14.8 0.5 2.2 2 0 0 2 2 2 0 Takusan Bap31_Bap29_C PF18035.1 EGE04522.1 - 0.027 14.5 0.8 0.027 14.5 0.8 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MOZART1 PF12554.8 EGE04522.1 - 0.12 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated LUD_dom PF02589.15 EGE04522.1 - 0.39 10.4 1.5 0.74 9.5 1.5 1.4 1 0 0 1 1 1 0 LUD domain PRKG1_interact PF15898.5 EGE04522.1 - 1.9 9.4 16.5 0.72 10.8 8.5 2.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 EGE04522.1 - 2 8.7 12.2 0.25 11.6 6.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.6 EGE04522.1 - 2.1 8.7 13.5 0.13 12.5 3.8 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) CorA PF01544.18 EGE04522.1 - 3.1 7.0 4.8 6 6.1 4.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cep57_MT_bd PF06657.13 EGE04522.1 - 4.7 7.7 11.0 4.6 7.8 1.3 3.6 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 SDA1 PF05285.12 EGE04523.1 - 2.1 7.7 18.9 2.1 7.7 18.9 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGE04523.1 - 2.7 6.2 14.9 2.7 6.2 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 EGE04523.1 - 3.3 7.4 8.3 3.2 7.5 8.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop14 PF04147.12 EGE04523.1 - 4.7 5.3 20.9 4.4 5.4 20.9 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 EGE04523.1 - 6.5 6.1 18.4 7.4 5.9 18.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FA_desaturase PF00487.24 EGE04524.1 - 3.6e-16 59.8 25.5 3.6e-16 59.8 25.5 1.9 1 1 1 2 2 2 1 Fatty acid desaturase GDPD PF03009.17 EGE04525.1 - 8.8e-17 61.7 0.0 1.3e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family adh_short PF00106.25 EGE04526.1 - 6.9e-18 64.8 0.0 7.6e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 EGE04526.1 - 2.9e-06 26.9 0.0 0.023 14.2 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EGE04526.1 - 2.8e-05 24.1 0.0 5.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EGE04526.1 - 0.00025 20.3 0.0 0.00065 18.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 EGE04526.1 - 0.018 14.6 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EGE04526.1 - 0.049 13.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGE04526.1 - 0.081 12.0 0.0 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EGE04526.1 - 0.17 12.3 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 EGE04527.1 - 5.2e-30 104.6 28.3 5.2e-30 104.6 28.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MTS PF05175.14 EGE04529.1 - 6.8e-07 29.0 0.0 6.2e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGE04529.1 - 9e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04529.1 - 0.00011 22.9 0.0 0.00024 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 EGE04529.1 - 0.00036 19.9 0.0 0.00087 18.6 0.0 1.5 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.12 EGE04529.1 - 0.00054 19.4 0.0 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 RNA methyltransferase PrmA PF06325.13 EGE04529.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 EGE04529.1 - 0.0015 18.0 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa PrmC_N PF17827.1 EGE04529.1 - 0.0019 18.8 0.7 0.0019 18.8 0.7 2.9 3 1 0 3 3 3 1 PrmC N-terminal domain Ubie_methyltran PF01209.18 EGE04529.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGE04529.1 - 0.13 13.0 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EGE04529.1 - 0.18 11.3 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Asp PF00026.23 EGE04530.1 - 1.7e-65 221.5 0.1 2.3e-65 221.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGE04530.1 - 7.4e-14 52.4 1.4 8.1e-10 39.2 2.5 3.1 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE04530.1 - 2.7e-05 24.7 0.5 0.095 13.4 0.1 3.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EGE04530.1 - 0.0017 18.9 0.0 0.62 10.7 0.0 3.4 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGE04530.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal APH PF01636.23 EGE04536.1 - 2.7e-10 40.6 0.0 1.2e-09 38.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Herpes_LMP1 PF05297.11 EGE04537.1 - 0.15 11.2 2.1 0.19 10.9 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_S8 PF00082.22 EGE04541.1 - 2.4e-31 109.1 0.5 2.4e-31 109.1 0.5 1.6 2 0 0 2 2 2 1 Subtilase family MotA_activ PF09114.10 EGE04541.1 - 0.15 12.2 0.7 0.44 10.7 0.1 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain 2-Hacid_dh_C PF02826.19 EGE04542.1 - 7.4e-48 162.3 0.0 1e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE04542.1 - 3.9e-13 49.2 0.0 6.3e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGE04542.1 - 4.1e-06 27.0 0.1 6.2e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGE04542.1 - 0.00053 20.5 0.1 0.001 19.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EGE04542.1 - 0.15 11.9 2.7 0.3 10.9 2.7 1.5 1 0 0 1 1 1 0 Rossmann-like domain Asparaginase PF00710.20 EGE04543.1 - 4.9e-57 192.6 0.0 7.2e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGE04543.1 - 7.8e-30 103.4 0.2 3.1e-29 101.5 0.3 1.9 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EGE04543.1 - 2.4e-11 44.1 0.2 2.7e-10 40.7 0.2 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGE04543.1 - 4e-10 39.7 4.7 2.3e-06 27.8 0.4 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGE04543.1 - 9.4e-09 34.8 1.8 0.00032 20.9 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGE04543.1 - 7.7e-08 32.5 0.1 3e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE04543.1 - 2.1e-07 31.3 0.1 5.7e-05 23.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MTTB PF06253.11 EGE04543.1 - 0.019 13.0 0.1 0.028 12.4 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.13 EGE04544.1 - 6.5e-69 232.0 0.0 7.9e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF1876 PF08962.11 EGE04544.1 - 0.18 11.8 1.5 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) NAP PF00956.18 EGE04545.1 - 8.3e-20 71.1 16.0 1.6e-19 70.1 6.8 2.4 2 1 1 3 3 3 2 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.11 EGE04546.1 - 3.5e-24 85.2 1.0 1.1e-23 83.7 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal APG17 PF04108.12 EGE04546.1 - 0.0017 17.6 2.8 0.055 12.6 0.2 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 DUF3618 PF12277.8 EGE04546.1 - 0.0032 17.7 7.3 0.89 9.9 0.1 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3618) HMMR_N PF15905.5 EGE04546.1 - 0.022 14.2 0.1 0.022 14.2 0.1 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4795 PF16043.5 EGE04546.1 - 0.022 14.3 0.9 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Phage_int_SAM_2 PF12834.7 EGE04546.1 - 0.093 13.4 0.1 0.24 12.1 0.1 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal Vps51 PF08700.11 EGE04546.1 - 0.11 12.6 3.9 9 6.5 0.0 3.4 3 1 0 3 3 3 0 Vps51/Vps67 Laminin_II PF06009.12 EGE04546.1 - 0.22 11.6 2.1 4.2 7.4 0.2 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4726 PF15855.5 EGE04546.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Cnn_1N PF07989.11 EGE04546.1 - 0.25 11.5 8.0 6.8 6.9 1.4 3.3 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF883 PF05957.13 EGE04546.1 - 0.36 11.5 4.9 20 5.9 0.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) GCIP PF13324.6 EGE04546.1 - 0.47 10.0 4.8 0.33 10.5 1.7 2.1 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting YtxH PF12732.7 EGE04546.1 - 0.5 10.9 3.4 2.3 8.8 0.5 2.6 2 1 0 2 2 2 0 YtxH-like protein SOAR PF16533.5 EGE04546.1 - 0.7 9.9 3.4 14 5.7 0.6 3.0 3 0 0 3 3 3 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 EGE04546.1 - 9.2 6.8 9.0 7.6 7.1 1.0 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_32 PF13679.6 EGE04547.1 - 1.6e-07 31.4 0.2 1.6e-07 31.4 0.2 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cytomega_UL20A PF05984.12 EGE04547.1 - 0.12 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein PTR2 PF00854.21 EGE04548.1 - 3.4e-78 263.2 8.9 4.5e-78 262.8 8.9 1.1 1 0 0 1 1 1 1 POT family Ank_2 PF12796.7 EGE04549.1 - 3.2e-34 117.4 4.8 9.8e-22 77.4 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE04549.1 - 1.4e-29 102.0 3.3 3.1e-15 56.3 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE04549.1 - 1.1e-19 70.2 2.6 1.9e-07 31.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGE04549.1 - 2.7e-18 65.5 1.9 3e-06 27.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EGE04549.1 - 9.2e-16 56.4 0.1 1.9e-06 27.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat bZIP_1 PF00170.21 EGE04549.1 - 0.0071 16.4 8.8 0.013 15.6 8.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor VWA_3_C PF18571.1 EGE04549.1 - 0.054 13.4 0.9 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain NACHT_N PF17100.5 EGE04549.1 - 0.11 12.3 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase DUF3328 PF11807.8 EGE04550.1 - 6e-48 163.5 0.4 7.5e-48 163.2 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LCCL PF03815.19 EGE04553.1 - 5.2e-20 71.4 0.1 8.2e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 LCCL domain CENP-B_dimeris PF09026.10 EGE04553.1 - 0.15 12.5 2.2 0.29 11.6 2.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2012 PF09430.10 EGE04554.1 - 6.8e-24 84.3 0.0 9.5e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EGE04554.1 - 0.093 12.3 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein AMP-binding PF00501.28 EGE04555.1 - 5.7e-83 278.9 0.0 6.9e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cys_Met_Meta_PP PF01053.20 EGE04556.1 - 7.3e-128 426.3 0.0 1.9e-124 415.1 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGE04556.1 - 1e-12 48.1 0.2 1.6e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EGE04556.1 - 4.4e-09 36.0 0.1 6.5e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGE04556.1 - 1.5e-07 30.8 0.2 2.5e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGE04556.1 - 0.00073 18.9 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Asparaginase_C PF17763.1 EGE04556.1 - 0.019 15.1 0.1 0.085 13.1 0.0 2.1 3 0 0 3 3 3 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 EGE04556.1 - 0.032 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Sulfotransfer_4 PF17784.1 EGE04557.1 - 5.6e-61 206.1 0.0 1.2e-60 205.0 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGE04557.1 - 8.6e-06 26.3 0.3 0.0084 16.5 0.3 2.4 1 1 0 1 1 1 1 Sulfotransferase family MARVEL PF01284.23 EGE04558.1 - 1.1e-12 48.2 15.2 1.3e-12 47.9 15.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain EF-hand_4 PF12763.7 EGE04559.1 - 4.3e-39 132.6 0.0 1.3e-15 57.2 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGE04559.1 - 4.4e-09 36.7 0.0 3.3e-05 24.2 0.0 4.3 2 1 2 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EGE04559.1 - 8e-07 28.2 0.4 0.018 14.6 0.0 5.3 6 0 0 6 6 6 1 EF hand EF-hand_6 PF13405.6 EGE04559.1 - 1.7e-05 24.3 1.0 7.7 6.7 0.0 6.1 6 0 0 6 6 6 1 EF-hand domain UBA PF00627.31 EGE04559.1 - 5.3e-05 23.0 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.6 EGE04559.1 - 0.0024 17.7 0.2 0.076 12.9 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair GAS PF13851.6 EGE04559.1 - 0.005 16.2 32.2 0.041 13.2 18.3 2.7 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding BicD PF09730.9 EGE04559.1 - 0.0059 15.1 26.9 0.073 11.5 25.8 2.0 1 1 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TMF_TATA_bd PF12325.8 EGE04559.1 - 0.25 11.5 29.7 0.077 13.2 4.6 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EGE04559.1 - 0.3 10.3 35.3 0.094 12.0 14.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.8 EGE04559.1 - 0.47 7.9 30.7 0.66 7.4 30.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 EGE04559.1 - 0.7 9.9 31.4 0.22 11.6 12.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EGE04559.1 - 0.74 8.6 27.5 1.1 8.0 27.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like FPP PF05911.11 EGE04559.1 - 0.98 7.5 24.6 1.5 6.9 24.6 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fib_alpha PF08702.10 EGE04559.1 - 2.2 8.5 21.2 0.021 15.0 7.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EGE04559.1 - 2.6 6.8 33.8 1 8.2 10.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 EGE04559.1 - 3.2 6.6 21.3 0.97 8.3 15.9 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Cep57_MT_bd PF06657.13 EGE04559.1 - 5.8 7.4 13.3 0.11 13.0 3.3 2.9 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 TPR_MLP1_2 PF07926.12 EGE04559.1 - 7.7 6.6 39.2 0.66 10.0 24.3 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Tubulin PF00091.25 EGE04560.1 - 6.9e-65 218.9 0.0 1.1e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGE04560.1 - 5.2e-48 162.4 0.2 9.7e-48 161.5 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGE04560.1 - 0.0017 18.1 0.0 0.005 16.5 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Pga1 PF10333.9 EGE04561.1 - 0.0016 18.3 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Creatinase_N_2 PF16189.5 EGE04562.1 - 5.6e-53 179.3 0.1 1.1e-51 175.2 0.1 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGE04562.1 - 7.3e-41 140.1 0.0 1.2e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EGE04562.1 - 2.9e-25 88.1 0.3 1e-24 86.4 0.3 2.0 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGE04562.1 - 3.7e-18 66.5 0.0 8.8e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Importin_rep_3 PF18806.1 EGE04563.1 - 0.021 14.8 0.0 0.53 10.4 0.0 2.6 2 0 0 2 2 2 0 Importin 13 repeat Xpo1 PF08389.12 EGE04563.1 - 0.029 14.5 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein Bcl-2 PF00452.19 EGE04563.1 - 0.078 13.7 0.2 27 5.5 0.0 3.7 3 0 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family SOR_SNZ PF01680.17 EGE04565.1 - 7.8e-108 359.0 5.2 1.3e-107 358.2 5.2 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGE04565.1 - 4.8e-09 35.9 8.5 1.3e-07 31.1 0.1 2.7 3 1 1 4 4 4 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGE04565.1 - 0.0019 17.4 0.6 0.32 10.0 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGE04565.1 - 0.0022 17.5 0.2 0.032 13.7 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 EGE04565.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain IGPS PF00218.21 EGE04565.1 - 0.0083 15.3 0.0 0.35 10.0 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 EGE04565.1 - 0.017 14.5 0.7 0.62 9.4 0.0 3.1 3 0 0 3 3 3 0 Thiamine monophosphate synthase NanE PF04131.14 EGE04565.1 - 0.024 13.8 0.8 0.26 10.5 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 EGE04565.1 - 0.044 13.4 0.1 0.39 10.3 0.0 2.2 1 1 2 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family FUN14 PF04930.15 EGE04566.1 - 2.4e-08 34.3 0.4 4.8e-08 33.3 0.4 1.5 1 1 0 1 1 1 1 FUN14 family TMEM43 PF07787.12 EGE04566.1 - 0.15 11.4 1.2 0.93 8.8 0.7 2.0 2 0 0 2 2 2 0 Transmembrane protein 43 ORC2 PF04084.14 EGE04567.1 - 2.8e-116 388.1 0.0 3.4e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 EGE04567.1 - 3.7 7.7 9.4 13 6.1 9.4 2.0 1 0 0 1 1 1 0 AT hook motif ArgJ PF01960.18 EGE04568.1 - 1.7e-121 405.5 0.0 2e-121 405.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.20 EGE04569.1 - 1.1e-64 218.7 4.8 1.2e-64 218.5 4.8 1.0 1 0 0 1 1 1 1 SecY translocase Spc42p PF11544.8 EGE04570.1 - 0.033 14.2 7.5 0.29 11.1 7.5 2.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p Sas6_CC PF18594.1 EGE04570.1 - 0.76 9.6 8.0 0.11 12.3 0.5 3.3 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain DUF641 PF04859.12 EGE04570.1 - 1.3 9.3 19.2 0.2 12.0 10.4 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 EGE04570.1 - 5.4 6.5 27.7 0.92 9.0 16.2 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 EGE04570.1 - 9.3 7.0 20.1 0.27 11.9 8.4 4.2 3 1 1 4 4 4 0 SlyX Promethin PF16015.5 EGE04571.1 - 6.6e-27 93.5 17.5 9e-27 93.1 17.5 1.2 1 0 0 1 1 1 1 Promethin MUG113 PF13455.6 EGE04572.1 - 4.9e-21 75.2 0.5 9.1e-21 74.3 0.5 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EGE04572.1 - 2.4e-20 73.0 0.2 6e-20 71.7 0.1 1.8 2 0 0 2 2 2 1 T5orf172 domain Glyco_transf_54 PF04666.13 EGE04573.1 - 1.3e-10 40.6 0.0 7e-10 38.2 0.0 1.9 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region WD40 PF00400.32 EGE04575.1 - 6.3e-22 77.5 5.6 1.4e-05 25.7 0.0 8.2 8 0 0 8 8 8 3 WD domain, G-beta repeat Peptidase_S8 PF00082.22 EGE04575.1 - 1.1e-17 64.2 0.0 1.9e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family ANAPC4_WD40 PF12894.7 EGE04575.1 - 9.8e-17 61.0 0.0 0.0017 18.6 0.0 6.4 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGE04575.1 - 4e-09 36.2 1.2 29 4.8 0.0 8.4 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 EGE04575.1 - 5.5e-07 29.6 0.9 4.6e-06 26.7 0.2 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGE04575.1 - 6.8e-05 23.3 0.0 0.00025 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 EGE04575.1 - 0.00011 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Ge1_WD40 PF16529.5 EGE04575.1 - 0.0017 17.3 0.0 1.6 7.6 0.0 4.0 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGE04575.1 - 0.0064 15.9 0.5 9 5.5 0.0 4.0 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EGE04575.1 - 0.0086 14.8 0.1 0.32 9.6 0.1 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 DUF1513 PF07433.11 EGE04575.1 - 0.016 14.3 0.0 0.44 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) AAA_30 PF13604.6 EGE04575.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.9 EGE04575.1 - 0.041 13.6 8.6 8.2 6.2 0.0 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PALB2_WD40 PF16756.5 EGE04575.1 - 0.12 11.3 0.1 7 5.5 0.1 2.6 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain tRNA-synt_2c PF01411.19 EGE04576.1 - 1.2e-09 37.3 0.1 1.6e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGE04576.1 - 4.3e-05 23.5 0.4 7.9e-05 22.7 0.4 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 EGE04577.1 - 7.1e-61 206.1 57.5 2.6e-44 151.6 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGE04577.1 - 4e-06 25.9 21.8 0.00066 18.6 4.4 3.9 1 1 3 4 4 4 3 MFS_1 like family Asp-Al_Ex PF06826.12 EGE04577.1 - 0.0038 17.1 5.9 0.0038 17.1 5.9 3.3 2 1 1 3 3 3 1 Predicted Permease Membrane Region OATP PF03137.20 EGE04577.1 - 0.0085 14.4 0.0 0.0085 14.4 0.0 3.0 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EGE04577.1 - 0.077 12.3 26.2 0.06 12.6 7.4 3.6 2 2 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGE04577.1 - 3.1 6.1 21.4 0.018 13.5 5.4 2.9 2 2 0 2 2 2 0 Transmembrane secretion effector ABC_membrane PF00664.23 EGE04579.1 - 2.9e-102 342.0 36.0 1.9e-52 178.6 11.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE04579.1 - 8.7e-46 155.8 0.0 3.4e-32 111.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE04579.1 - 6.4e-13 48.7 0.0 4.2e-05 23.1 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGE04579.1 - 0.00041 19.3 3.2 0.094 11.5 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 EGE04579.1 - 0.00044 20.7 1.8 0.31 11.5 0.4 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE04579.1 - 0.0039 17.6 0.5 0.022 15.1 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGE04579.1 - 0.004 17.4 0.2 0.049 13.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGE04579.1 - 0.008 16.4 3.4 6.1 7.1 0.5 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGE04579.1 - 0.026 14.4 0.6 1.3 8.7 0.0 3.5 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGE04579.1 - 0.029 14.1 0.7 0.34 10.6 0.2 2.6 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGE04579.1 - 0.032 14.2 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain SAA PF00277.18 EGE04579.1 - 0.038 14.4 1.2 1.1 9.8 0.0 2.9 3 0 0 3 3 2 0 Serum amyloid A protein Skp1 PF01466.19 EGE04581.1 - 3e-28 97.7 0.5 4.8e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGE04581.1 - 1.7e-24 85.7 0.2 4.2e-24 84.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DFF-C PF09033.10 EGE04581.1 - 0.044 13.7 0.1 0.081 12.8 0.0 1.5 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain Glyco_transf_22 PF03901.17 EGE04582.1 - 6.1e-58 197.0 20.6 8.5e-58 196.5 20.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF420 PF04238.12 EGE04582.1 - 1.8 8.8 6.8 0.16 12.2 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF420) XPC-binding PF09280.11 EGE04583.1 - 8.9e-25 86.2 17.2 1.3e-24 85.6 17.2 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EGE04583.1 - 1.6e-22 79.1 0.1 3e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGE04583.1 - 6.3e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGE04583.1 - 1.8e-08 34.1 0.4 3.4e-08 33.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1631 PF07793.11 EGE04583.1 - 0.009 14.5 5.2 0.011 14.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) Rad60-SLD_2 PF13881.6 EGE04583.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EGE04583.1 - 0.021 15.2 0.1 0.039 14.3 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EGE04583.1 - 0.08 13.4 0.2 0.27 11.7 0.1 2.0 2 2 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EGE04583.1 - 0.094 12.6 0.2 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Pheromone PF08015.11 EGE04583.1 - 1.9 9.6 6.0 1.6 9.8 4.1 1.9 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF3431 PF11913.8 EGE04584.1 - 1.4e-78 263.6 4.0 4.1e-78 262.1 0.5 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) Sigma70_r4 PF04545.16 EGE04584.1 - 0.11 12.1 0.2 0.37 10.4 0.2 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 Aminotran_1_2 PF00155.21 EGE04585.1 - 7.2e-44 150.4 0.0 8.7e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE04585.1 - 3.1e-11 42.4 0.0 4.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGE04585.1 - 2e-09 36.9 0.0 3.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGE04585.1 - 5.5e-06 25.9 0.0 6.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase PHO4 PF01384.20 EGE04586.1 - 7.9e-125 416.4 15.5 9.2e-125 416.2 15.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Alpha-2-MRAP_C PF06401.11 EGE04586.1 - 0.25 11.3 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Pkinase_Tyr PF07714.17 EGE04587.1 - 2.5e-14 53.2 0.0 3.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGE04587.1 - 1.2e-11 44.5 0.0 2.3e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGE04587.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE04587.1 - 0.038 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGE04587.1 - 0.045 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TauD PF02668.16 EGE04589.1 - 4.3e-42 144.7 0.0 5.2e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1330 PF07045.11 EGE04589.1 - 0.089 13.1 0.0 6 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) Zn_clus PF00172.18 EGE04590.1 - 0.00012 22.1 8.2 0.00025 21.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 EGE04590.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family SRR1 PF07985.12 EGE04591.1 - 8e-14 51.4 0.0 3.8e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 SRR1 eIF-6 PF01912.18 EGE04592.1 - 2.5e-79 265.3 0.7 3.2e-79 264.9 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family Ank_2 PF12796.7 EGE04593.1 - 1.4e-27 96.1 5.7 4.5e-12 46.4 0.1 4.6 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE04593.1 - 3.2e-24 85.0 2.7 3.1e-08 34.0 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE04593.1 - 3.3e-17 62.3 6.6 1.4e-09 38.0 0.1 5.9 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04593.1 - 7e-16 56.7 5.9 2.3e-05 24.4 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EGE04593.1 - 7.1e-13 48.4 6.8 5.2e-06 26.7 0.1 6.7 6 1 0 6 6 6 2 Ankyrin repeat F-box-like PF12937.7 EGE04593.1 - 0.00014 21.7 0.2 0.00029 20.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE04593.1 - 0.00016 21.5 0.3 0.00034 20.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain SQHop_cyclase_C PF13243.6 EGE04596.1 - 7.2e-46 156.7 0.2 5e-44 150.7 0.1 2.6 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGE04596.1 - 3.5e-44 151.1 1.1 2.5e-37 128.6 0.1 3.5 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGE04596.1 - 3.1e-32 110.0 4.5 5.1e-10 38.9 0.0 5.2 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EGE04596.1 - 1e-05 25.1 0.9 0.15 11.4 0.1 4.2 2 1 0 3 3 3 2 Pectic acid lyase TED_complement PF07678.14 EGE04596.1 - 0.0048 16.0 0.1 0.055 12.5 0.2 2.5 2 1 1 3 3 3 1 A-macroglobulin TED domain SGS PF05002.15 EGE04597.1 - 1e-27 96.0 9.0 6.4e-27 93.5 9.0 2.3 1 1 0 1 1 1 1 SGS domain CS PF04969.16 EGE04597.1 - 4e-18 66.2 0.0 8.9e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EGE04597.1 - 0.00024 20.8 1.0 0.0086 15.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE04597.1 - 0.0063 16.5 1.5 1.3 9.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE04597.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat CcmH PF03918.14 EGE04597.1 - 0.065 12.5 0.2 0.14 11.4 0.2 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein PQ-loop PF04193.14 EGE04598.1 - 3.4e-40 135.6 10.2 2.2e-20 72.2 1.0 2.7 2 0 0 2 2 2 2 PQ loop repeat NMN_transporter PF04973.12 EGE04598.1 - 4.1 7.3 11.2 0.23 11.4 2.9 2.7 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter adh_short PF00106.25 EGE04599.1 - 8.7e-41 139.5 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE04599.1 - 4.7e-27 95.0 0.0 6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGE04599.1 - 4.6e-07 29.5 0.0 6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGE04599.1 - 2.1e-06 27.8 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain ABC_tran PF00005.27 EGE04600.1 - 6.2e-08 33.3 0.1 2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGE04600.1 - 0.00011 21.7 0.1 0.00014 21.4 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGE04600.1 - 0.082 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 EGE04601.1 - 9e-74 248.6 30.9 6.5e-37 127.7 16.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE04601.1 - 4.7e-32 111.4 0.0 9.9e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGE04601.1 - 8.3e-07 28.7 0.0 0.0051 16.3 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGE04601.1 - 0.001 19.5 0.1 0.0036 17.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGE04601.1 - 0.0015 18.8 0.0 0.013 15.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 EGE04601.1 - 0.0038 16.1 0.1 0.0075 15.1 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EGE04601.1 - 0.0086 16.0 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 EGE04601.1 - 0.031 14.5 0.3 0.18 12.1 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGE04601.1 - 0.044 13.5 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM100 PF16311.5 EGE04601.1 - 0.057 13.0 0.2 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 100 AAA_15 PF13175.6 EGE04601.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GCD14 PF08704.10 EGE04602.1 - 1.5e-62 211.5 0.0 1.6e-61 208.2 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.19 EGE04603.1 - 1.3e-114 382.7 0.0 1.9e-114 382.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGE04603.1 - 2.6e-05 23.2 0.4 0.088 11.5 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EGE04603.1 - 0.00059 20.3 0.1 0.0018 18.7 0.1 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 EGE04603.1 - 0.052 12.5 0.0 0.9 8.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) 5_nucleotid_C PF02872.18 EGE04604.1 - 3.8e-36 124.7 0.0 7.6e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGE04604.1 - 0.00038 21.0 0.0 0.00079 20.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DegT_DnrJ_EryC1 PF01041.17 EGE04606.1 - 6.1e-60 203.4 0.0 1.1e-59 202.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GFO_IDH_MocA PF01408.22 EGE04606.1 - 7.8e-19 68.7 0.0 2e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Beta_elim_lyase PF01212.21 EGE04606.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGE04606.1 - 0.00072 18.6 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V CoA_binding PF02629.19 EGE04606.1 - 0.0013 19.4 0.0 0.0043 17.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Cys_Met_Meta_PP PF01053.20 EGE04606.1 - 0.0029 16.2 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Semialdhyde_dh PF01118.24 EGE04606.1 - 0.0072 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EGE04606.1 - 0.031 14.3 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.28 EGE04607.1 - 2e-73 247.4 0.0 2.8e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGE04607.1 - 5.8e-32 111.0 0.0 1.5e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE04607.1 - 2.3e-10 40.7 0.0 7.2e-09 35.9 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ank_5 PF13857.6 EGE04608.1 - 1.1e-17 63.8 3.9 3.8e-09 36.6 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE04608.1 - 2.9e-13 50.2 0.2 9.8e-13 48.5 0.1 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE04608.1 - 3.5e-11 43.4 0.0 8e-06 26.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04608.1 - 1.2e-07 31.4 0.4 0.031 14.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGE04608.1 - 5.5e-07 29.7 0.9 0.059 13.8 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeat bZIP_1 PF00170.21 EGE04608.1 - 0.075 13.1 7.0 0.16 12.1 7.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor TPR_2 PF07719.17 EGE04609.1 - 4.3e-06 26.4 0.6 0.53 10.5 0.3 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 EGE04609.1 - 0.00046 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.28 EGE04609.1 - 0.0024 17.6 0.0 3.4 7.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE04609.1 - 0.016 15.5 0.0 0.39 11.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 EGE04609.1 - 0.05 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.11 EGE04611.1 - 2.8e-183 609.4 0.0 3.4e-183 609.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) F-box-like PF12937.7 EGE04612.1 - 6.6e-08 32.3 0.0 1.4e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EGE04612.1 - 0.0013 19.0 2.4 40 4.8 0.1 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EGE04612.1 - 0.044 13.7 0.2 4.3 7.3 0.0 3.3 3 0 0 3 3 3 0 F-box domain PH PF00169.29 EGE04613.1 - 3.2e-05 24.4 0.3 8.4e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 PH domain KASH_CCD PF14662.6 EGE04616.1 - 0.004 17.0 3.3 0.0085 15.9 3.3 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TrkH PF02386.16 EGE04619.1 - 2.1e-145 485.0 1.8 5.7e-143 477.0 2.1 2.1 2 0 0 2 2 2 2 Cation transport protein COesterase PF00135.28 EGE04620.1 - 6.5e-83 279.3 0.0 5.8e-75 253.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE04620.1 - 2e-14 54.0 0.0 3.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE04620.1 - 0.00066 20.3 1.4 0.0011 19.6 0.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EGE04620.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2264 PF10022.9 EGE04620.1 - 0.021 13.9 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Abhydrolase_1 PF00561.20 EGE04620.1 - 0.025 14.2 0.1 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGE04620.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EGE04620.1 - 0.17 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dynamin_M PF01031.20 EGE04621.1 - 1.5e-101 339.4 0.0 2.9e-101 338.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EGE04621.1 - 5.2e-57 192.6 0.2 9.8e-57 191.7 0.2 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGE04621.1 - 8.5e-30 102.8 2.8 2.2e-29 101.4 2.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGE04621.1 - 6.3e-06 26.2 1.1 3.7e-05 23.8 1.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2738 PF10927.8 EGE04621.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) AAA_16 PF13191.6 EGE04621.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EGE04621.1 - 0.26 11.0 3.2 2.1 8.0 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGE04622.1 - 1e-109 365.2 0.0 1.5e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGE04622.1 - 1.6e-44 150.6 0.0 3.7e-44 149.5 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGE04622.1 - 1.7e-14 54.1 3.6 3.7e-14 53.0 3.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HSBP1 PF06825.12 EGE04622.1 - 0.1 12.5 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 WD40 PF00400.32 EGE04624.1 - 3.7e-25 87.7 8.1 0.0001 23.0 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04624.1 - 9.1e-15 54.7 0.8 0.0017 18.6 0.0 5.5 2 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE04624.1 - 0.00012 21.2 0.1 0.021 13.8 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGE04624.1 - 0.00036 20.4 0.2 14 5.7 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGE04624.1 - 0.0018 18.2 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGE04624.1 - 0.076 11.5 0.0 0.75 8.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain DEAD PF00270.29 EGE04625.1 - 1.3e-41 142.3 0.1 2.3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE04625.1 - 1.6e-33 115.4 0.1 6.5e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGE04625.1 - 0.00068 19.4 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGE04625.1 - 0.00085 19.4 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGE04625.1 - 0.0028 18.0 0.1 0.027 14.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 EGE04625.1 - 0.037 14.0 0.3 0.14 12.1 0.1 2.2 1 1 1 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EGE04625.1 - 0.05 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 EGE04625.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EGE04625.1 - 0.22 11.8 1.0 1.2 9.4 1.0 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 EGE04626.1 - 2.2e-76 255.7 0.3 2.2e-76 255.7 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGE04626.1 - 4.7e-23 81.5 1.8 7.1e-23 80.9 0.6 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGE04626.1 - 2.1e-11 43.5 0.2 4.7e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EGE04626.1 - 2.7e-09 37.1 3.9 1.2e-07 31.9 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGE04626.1 - 7.4e-08 32.5 1.0 7.4e-08 32.5 1.0 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGE04626.1 - 0.00023 21.5 0.2 0.011 16.0 0.0 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EGE04626.1 - 0.053 13.4 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EGE04626.1 - 0.087 13.7 1.4 5.3 8.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger PRP9_N PF16958.5 EGE04626.1 - 1.5 8.8 20.2 0.3 11.1 1.2 3.6 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2 PF00096.26 EGE04626.1 - 2.8 8.6 4.3 5.6 7.6 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Inhibitor_I48 PF10467.9 EGE04627.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin DNA_ligase_A_M PF01068.21 EGE04628.1 - 5.4e-23 81.7 0.0 8.8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGE04628.1 - 1.8e-19 70.7 0.0 3.3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus ANAPC8 PF04049.13 EGE04629.1 - 6.3e-53 178.6 0.0 1.4e-52 177.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EGE04629.1 - 9.2e-25 85.4 9.0 0.00018 21.2 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGE04629.1 - 9.1e-21 72.3 18.5 1.8e-05 24.6 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGE04629.1 - 1.9e-20 71.3 23.6 0.061 13.5 2.8 9.2 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGE04629.1 - 2.1e-11 43.6 21.7 0.007 17.1 0.0 8.8 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGE04629.1 - 4.7e-11 42.2 4.0 1.1e-06 28.2 0.3 4.9 3 2 2 5 5 5 2 TPR repeat TPR_12 PF13424.6 EGE04629.1 - 1.1e-10 41.7 7.8 0.24 11.7 0.0 7.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE04629.1 - 1.4e-10 41.5 13.8 0.065 13.8 0.4 7.6 7 2 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE04629.1 - 4.7e-10 40.0 20.1 1.7e-05 25.4 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE04629.1 - 5.8e-10 39.2 13.5 0.00012 22.1 0.4 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE04629.1 - 1e-07 32.1 20.2 0.11 12.8 0.3 6.7 8 0 0 8 8 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGE04629.1 - 4.4e-06 26.7 9.4 1.3 9.5 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE04629.1 - 0.00026 20.8 9.8 1.9 8.7 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGE04629.1 - 0.00072 20.0 27.0 0.72 10.6 0.2 9.0 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGE04629.1 - 0.0035 16.6 9.9 0.0039 16.5 4.5 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 EGE04629.1 - 0.035 14.8 6.5 7 7.5 0.1 4.2 3 0 0 3 3 3 0 Sel1 repeat HrpB1_HrpK PF09613.10 EGE04629.1 - 0.053 13.2 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 EGE04629.1 - 0.27 11.3 3.5 0.5 10.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EGE04629.1 - 1.3 9.4 4.8 38 4.8 0.0 4.5 5 0 0 5 5 5 0 PPR repeat polyprenyl_synt PF00348.17 EGE04630.1 - 1.4e-90 302.9 0.0 1.7e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Glycogen_syn PF05693.13 EGE04631.1 - 0 1137.7 0.0 0 1137.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EGE04631.1 - 1.4e-05 25.1 0.2 3.6e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGE04631.1 - 2.2e-05 24.1 0.0 0.0064 16.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGE04631.1 - 2.7e-05 24.6 0.0 0.031 14.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGE04631.1 - 0.00016 22.2 0.1 0.00037 21.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EGE04631.1 - 0.00016 21.4 0.1 0.00035 20.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain NPCC PF08058.11 EGE04632.1 - 2.4e-24 85.8 0.0 3.7e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.28 EGE04633.1 - 2.3e-16 59.4 0.0 1.7e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Ribosomal_L19 PF01245.20 EGE04635.1 - 2.3e-11 43.6 0.1 5.5e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L19 Methyltransf_24 PF13578.6 EGE04636.1 - 3.2e-12 47.4 0.0 4.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EGE04636.1 - 0.0014 17.8 0.1 0.0063 15.7 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase TylF PF05711.11 EGE04636.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) bZIP_1 PF00170.21 EGE04637.1 - 4e-08 33.2 11.3 1.1e-07 31.9 11.3 1.7 1 0 0 1 1 1 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 EGE04637.1 - 1e-07 31.8 6.9 2.3e-07 30.7 6.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Fmp27_WPPW PF10359.9 EGE04637.1 - 0.02 13.7 3.4 0.03 13.2 3.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 EGE04637.1 - 0.023 13.6 7.2 0.035 13.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) dsrm PF00035.26 EGE04637.1 - 0.074 13.8 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif PSI_PsaF PF02507.15 EGE04637.1 - 0.19 11.6 1.2 0.34 10.7 1.2 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III bZIP_2 PF07716.15 EGE04637.1 - 0.25 11.5 17.3 1.2 9.3 16.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 EGE04637.1 - 0.38 11.4 7.4 1.3 9.7 6.3 2.4 1 1 1 2 2 2 0 SlyX bZIP_Maf PF03131.17 EGE04637.1 - 0.66 10.5 11.5 2.5 8.7 11.5 2.0 1 0 0 1 1 1 0 bZIP Maf transcription factor Golgin_A5 PF09787.9 EGE04637.1 - 1.1 8.6 13.0 1.4 8.3 11.5 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EGE04637.1 - 8.1 5.7 8.3 13 5.0 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 EGE04638.1 - 8e-10 38.5 0.8 0.01 15.7 0.0 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein Fer2 PF00111.27 EGE04639.1 - 3.4e-14 52.6 0.6 5e-14 52.0 0.6 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 EGE04640.1 - 1.6e-35 122.4 7.9 1.6e-35 122.4 7.9 2.0 3 0 0 3 3 3 1 Rrp15p RRN3 PF05327.11 EGE04640.1 - 0.57 8.7 4.7 0.77 8.2 4.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FliL PF03748.14 EGE04640.1 - 2 9.0 5.5 13 6.4 0.0 3.0 2 1 1 3 3 3 0 Flagellar basal body-associated protein FliL Ndc1_Nup PF09531.10 EGE04640.1 - 2.4 6.8 5.6 3.1 6.4 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP54 PF00448.22 EGE04641.1 - 2.6e-74 249.1 1.9 5.2e-74 248.1 1.9 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGE04641.1 - 2.6e-28 98.5 0.1 2.6e-28 98.5 0.1 4.3 2 2 3 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.19 EGE04641.1 - 6.5e-20 71.1 0.4 1.6e-19 69.9 0.4 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGE04641.1 - 4e-07 29.8 0.6 1.6e-06 27.9 0.5 2.0 2 1 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGE04641.1 - 2.8e-06 27.5 0.1 7.8e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGE04641.1 - 6.3e-05 22.3 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EGE04641.1 - 7.6e-05 23.2 0.1 7.6e-05 23.2 0.1 2.3 3 0 0 3 3 1 1 AAA domain MeaB PF03308.16 EGE04641.1 - 0.00038 19.5 0.7 0.0038 16.2 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EGE04641.1 - 0.00045 20.6 0.0 0.0013 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.17 EGE04641.1 - 0.00064 19.6 0.6 0.025 14.3 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein 6PF2K PF01591.18 EGE04641.1 - 0.0018 17.7 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 EGE04641.1 - 0.0018 18.2 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 EGE04641.1 - 0.003 17.3 2.2 0.0036 17.1 0.2 2.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EGE04641.1 - 0.0031 17.5 1.0 0.012 15.6 1.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 EGE04641.1 - 0.0052 16.5 0.1 0.02 14.5 0.1 2.0 1 0 0 1 1 1 1 Thymidylate kinase SRPRB PF09439.10 EGE04641.1 - 0.0053 16.2 2.2 2.1 7.8 1.8 3.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit CbiA PF01656.23 EGE04641.1 - 0.0062 16.6 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EGE04641.1 - 0.0067 16.7 0.0 0.029 14.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGE04641.1 - 0.015 15.9 0.1 0.04 14.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain Methyltransf_25 PF13649.6 EGE04641.1 - 0.02 15.6 0.5 1.7 9.4 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain MMR_HSR1 PF01926.23 EGE04641.1 - 0.022 14.8 0.2 0.097 12.8 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGE04641.1 - 0.034 13.9 0.1 0.086 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGE04641.1 - 0.035 13.6 0.0 0.09 12.2 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_19 PF13245.6 EGE04641.1 - 0.038 14.3 0.2 0.096 13.0 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGE04641.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGE04641.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.6 EGE04641.1 - 0.071 13.0 0.6 0.62 10.0 0.1 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGE04641.1 - 0.074 13.6 0.8 0.3 11.6 0.1 2.1 2 1 0 2 2 2 0 ABC transporter VirE PF05272.11 EGE04641.1 - 0.082 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Virulence-associated protein E DUF2075 PF09848.9 EGE04641.1 - 0.11 11.6 0.2 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NolV PF06635.12 EGE04641.1 - 0.13 11.6 0.4 0.28 10.6 0.4 1.4 1 0 0 1 1 1 0 Nodulation protein NolV PhoD PF09423.10 EGE04642.1 - 2.9e-38 131.8 0.0 9.3e-38 130.1 0.0 1.8 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EGE04642.1 - 0.058 14.0 1.1 0.28 11.8 1.1 2.2 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Glyco_hydro_18 PF00704.28 EGE04643.1 - 1e-15 58.3 0.0 1.2e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S64 PF08192.11 EGE04645.1 - 0.0017 16.9 0.0 0.002 16.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S64 adh_short_C2 PF13561.6 EGE04647.1 - 6.5e-57 192.8 0.0 8e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE04647.1 - 1.3e-46 158.6 0.0 1.9e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE04647.1 - 1.4e-11 44.6 0.5 2.3e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGE04647.1 - 0.01 14.9 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c PF02518.26 EGE04647.1 - 0.047 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.21 EGE04647.1 - 0.05 13.1 0.1 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CcmE PF03100.15 EGE04647.1 - 0.062 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 CcmE YjeF_N PF03853.15 EGE04647.1 - 0.077 12.9 0.0 0.44 10.4 0.0 2.0 1 1 0 2 2 2 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 EGE04647.1 - 0.12 11.7 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fez1 PF06818.15 EGE04648.1 - 0.011 16.2 29.6 0.011 16.2 29.6 4.2 2 2 2 4 4 4 0 Fez1 Macoilin PF09726.9 EGE04648.1 - 0.025 13.2 71.2 0.24 9.9 39.2 2.4 2 1 0 2 2 2 0 Macoilin family Baculo_PEP_C PF04513.12 EGE04648.1 - 0.42 10.6 23.5 0.28 11.2 5.1 4.1 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus CoA_transf_3 PF02515.17 EGE04649.1 - 1.1e-68 232.1 0.0 1.3e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DNA_ligase_OB_2 PF14743.6 EGE04649.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain Methyltransf_23 PF13489.6 EGE04652.1 - 9.9e-16 58.0 0.0 3.9e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04652.1 - 0.00024 21.8 0.1 0.0062 17.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE04652.1 - 0.0048 17.5 0.0 0.0085 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE04652.1 - 0.0088 16.8 0.0 0.023 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE04652.1 - 0.061 13.1 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CAF1A PF12253.8 EGE04654.1 - 6.6e-22 77.5 4.4 6.6e-22 77.5 4.4 3.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 EGE04654.1 - 0.00037 20.2 59.7 0.00068 19.4 59.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.8 EGE04654.1 - 0.023 13.8 23.1 0.037 13.2 23.1 1.3 1 0 0 1 1 1 0 SprA-related family Mem_trans PF03547.18 EGE04654.1 - 0.34 9.2 2.5 0.47 8.8 2.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Asp-B-Hydro_N PF05279.11 EGE04654.1 - 1.1 9.2 36.5 2.3 8.2 36.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF966 PF06136.13 EGE04654.1 - 1.2 8.8 23.6 2.1 8.0 23.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.9 EGE04654.1 - 1.4 7.7 38.4 2 7.1 38.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_S64 PF08192.11 EGE04654.1 - 3.8 5.9 18.7 5.7 5.3 18.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF262 PF03235.14 EGE04654.1 - 4.4 7.4 12.2 9.4 6.3 12.2 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF262 CNDH2_C PF16858.5 EGE04654.1 - 5.6 6.8 36.5 5.3 6.8 26.1 3.1 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4666 PF15697.5 EGE04655.1 - 0.17 12.5 4.2 0.23 12.2 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) Roughex PF06020.11 EGE04655.1 - 0.79 8.8 10.2 0.86 8.6 10.2 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Swm2 PF17083.5 EGE04656.1 - 0.034 14.2 0.1 0.075 13.0 0.1 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 IPP-2 PF04979.14 EGE04657.1 - 4.2e-20 72.8 16.4 4.2e-20 72.8 16.4 2.3 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CRAL_TRIO PF00650.20 EGE04658.1 - 1.6e-12 47.4 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE04658.1 - 3.7e-09 36.6 0.0 1.1e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TAF6_C PF07571.13 EGE04659.1 - 1.4e-30 105.5 0.0 3.1e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EGE04659.1 - 4.1e-25 87.7 0.0 2.1e-24 85.5 0.0 2.2 3 0 0 3 3 3 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EGE04659.1 - 0.0015 18.6 0.1 0.0044 17.1 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGE04659.1 - 0.0086 16.4 0.0 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGE04659.1 - 0.0098 15.9 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EGE04659.1 - 0.059 13.7 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 EGE04659.1 - 0.12 12.1 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SAM_decarbox PF01536.16 EGE04660.1 - 1.3e-130 435.6 0.0 1.5e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAFII28 PF04719.14 EGE04661.1 - 7.6e-29 99.7 1.1 2.7e-26 91.5 0.4 2.6 2 1 0 2 2 2 2 hTAFII28-like protein conserved region SRP-alpha_N PF04086.13 EGE04661.1 - 0.65 9.9 13.8 0.32 10.9 3.2 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal 60KD_IMP PF02096.20 EGE04662.1 - 3.4e-20 72.6 0.1 5.7e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF5326 PF17260.2 EGE04662.1 - 0.076 13.2 0.5 0.16 12.1 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) TOM13 PF08219.11 EGE04663.1 - 9e-34 115.3 0.0 1.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 EGE04664.1 - 1.3e-22 80.2 0.1 2.8e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EGE04664.1 - 5.7e-14 52.1 0.0 8.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EGE04664.1 - 7.6e-14 51.3 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EGE04664.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain ParA PF10609.9 EGE04665.1 - 1.2e-85 286.9 0.1 1.4e-59 201.6 0.0 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGE04665.1 - 1.5e-09 38.0 0.0 3.5e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EGE04665.1 - 5e-05 22.7 0.0 0.00011 21.5 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EGE04665.1 - 0.00011 22.2 0.1 0.00042 20.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EGE04665.1 - 0.00047 19.4 0.3 0.00098 18.4 0.3 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 EGE04665.1 - 0.00074 19.2 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EGE04665.1 - 0.011 15.5 0.8 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 EGE04665.1 - 0.031 13.8 0.4 0.089 12.3 0.2 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EGE04665.1 - 0.047 12.7 0.2 0.077 12.0 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB OrfB_Zn_ribbon PF07282.11 EGE04665.1 - 0.077 12.9 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain CLP1_P PF16575.5 EGE04665.1 - 0.081 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EGE04665.1 - 0.09 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase COG2 PF06148.11 EGE04669.1 - 4.7e-30 104.4 1.1 9.2e-30 103.4 1.1 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EGE04669.1 - 1.1e-05 25.5 1.7 2.4e-05 24.3 0.2 2.3 1 1 1 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.14 EGE04669.1 - 0.021 14.7 0.4 0.042 13.7 0.4 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain KxDL PF10241.9 EGE04669.1 - 0.031 14.6 0.7 0.11 12.8 0.7 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein Vps54_N PF10475.9 EGE04669.1 - 0.033 13.5 0.2 0.069 12.4 0.1 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 EGE04669.1 - 0.046 13.9 1.3 0.06 13.5 0.3 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 BLOC1S3 PF15753.5 EGE04669.1 - 0.049 13.8 1.2 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Spc7 PF08317.11 EGE04669.1 - 0.055 12.3 3.4 0.085 11.7 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EGE04669.1 - 0.069 12.2 1.3 0.12 11.4 1.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Dor1 PF04124.12 EGE04669.1 - 0.086 11.5 1.4 0.12 11.0 1.4 1.2 1 0 0 1 1 1 0 Dor1-like family IFT20 PF14931.6 EGE04669.1 - 0.098 12.8 1.7 0.3 11.3 1.7 1.8 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF1690 PF07956.11 EGE04669.1 - 0.18 12.2 2.2 0.48 10.9 2.2 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) FTCD_C PF04961.12 EGE04669.1 - 0.19 11.4 0.3 0.77 9.5 0.0 1.9 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase Bul1_C PF04426.12 EGE04669.1 - 0.21 11.0 0.9 7.4 5.9 0.0 2.1 1 1 1 2 2 2 0 Bul1 C terminus UPF0242 PF06785.11 EGE04669.1 - 0.42 10.7 4.7 0.58 10.2 3.3 1.9 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sds3 PF08598.11 EGE04669.1 - 0.56 10.2 4.8 1.3 9.0 4.8 1.7 1 1 0 1 1 1 0 Sds3-like Seryl_tRNA_N PF02403.22 EGE04669.1 - 1.3 9.3 5.3 3 8.1 0.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L1 PF00687.21 EGE04670.1 - 8.1e-34 117.2 0.0 1.3e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Glyco_hydro_16 PF00722.21 EGE04671.1 - 3.2e-06 26.7 0.0 7.5e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAD_binding_3 PF01494.19 EGE04672.1 - 5.4e-64 216.6 0.0 9e-63 212.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGE04672.1 - 2.4e-24 86.2 0.0 6.2e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EGE04672.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NMT1 PF09084.11 EGE04673.1 - 0.00073 19.5 0.0 0.014 15.4 0.0 2.3 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 EGE04673.1 - 0.0058 16.1 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1_2 PF13379.6 EGE04673.1 - 0.0072 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EGE04673.1 - 0.03 13.8 0.0 0.21 11.0 0.0 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 PQ-loop PF04193.14 EGE04675.1 - 1.2e-20 73.1 4.2 5.1e-13 48.6 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EGE04675.1 - 0.0011 19.8 2.9 0.0043 17.9 2.9 1.9 1 1 0 1 1 1 1 ER lumen protein retaining receptor Phage_holin_5_2 PF16079.5 EGE04675.1 - 0.053 13.8 1.4 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Glyco_hydro_31 PF01055.26 EGE04676.1 - 2.9e-137 458.5 6.2 5.2e-137 457.6 6.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGE04676.1 - 1.3e-26 92.7 0.5 1.2e-25 89.6 0.2 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGE04676.1 - 5.1e-08 33.1 0.3 1.9e-07 31.3 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NDK PF00334.19 EGE04677.1 - 6.3e-55 184.9 0.0 7.2e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.9 EGE04678.1 - 1.3e-29 102.4 0.0 2.2e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EGE04678.1 - 0.0042 17.6 0.4 0.0052 17.3 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) MTHFR PF02219.17 EGE04679.1 - 5.1e-101 337.8 0.0 8.5e-101 337.1 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.16 EGE04680.1 - 1.3e-32 113.1 28.5 1.3e-32 113.1 28.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TGT PF01702.18 EGE04681.1 - 2.9e-62 210.8 0.0 3.6e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylate_kin PF02223.17 EGE04682.1 - 1.4e-43 148.8 0.0 1.6e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EGE04682.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EGE04682.1 - 0.0018 17.8 0.1 0.0077 15.7 0.0 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 GIY-YIG PF01541.24 EGE04683.1 - 1.1e-15 57.7 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EGE04683.1 - 4.9e-05 23.4 3.4 8.6e-05 22.6 3.4 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EGE04683.1 - 0.027 14.7 1.2 0.05 13.9 1.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 EGE04683.1 - 0.18 11.7 4.7 0.34 10.8 4.7 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EGE04683.1 - 0.64 10.0 5.6 0.39 10.7 2.5 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1272 PF06906.11 EGE04683.1 - 1 9.5 5.3 0.34 11.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PLU-1 PF08429.11 EGE04684.1 - 1e-109 366.9 16.0 1.8e-107 359.4 14.5 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EGE04684.1 - 2.2e-42 144.1 1.0 6.4e-42 142.6 0.4 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 EGE04684.1 - 8.2e-22 77.7 0.1 2.5e-21 76.1 0.1 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EGE04684.1 - 1.5e-18 66.5 3.2 3.7e-18 65.2 3.2 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EGE04684.1 - 4e-17 61.8 28.4 4.5e-09 36.1 7.4 3.6 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 EGE04684.1 - 2.5e-12 47.0 5.2 8.6e-12 45.3 5.2 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger PHD_2 PF13831.6 EGE04684.1 - 0.0027 17.2 2.6 0.0027 17.2 2.6 2.7 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 EGE04684.1 - 0.29 10.7 16.1 0.077 12.6 2.7 3.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EGE04684.1 - 0.88 9.7 21.2 0.27 11.4 4.8 3.1 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 EGE04684.1 - 2.9 7.8 24.3 0.25 11.3 3.9 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF515 PF04415.12 EGE04684.1 - 3.9 5.8 4.2 11 4.3 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DHHA2 PF02833.14 EGE04685.1 - 3.6e-34 118.0 0.1 6.4e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EGE04685.1 - 9.9e-06 25.7 0.0 6.9e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 DHH family Transglut_core PF01841.19 EGE04686.1 - 3.9e-11 43.4 0.2 1e-10 42.0 0.2 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EGE04686.1 - 1.5e-08 34.2 0.1 3.7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGE04686.1 - 1.2e-05 24.9 0.1 1.2e-05 24.9 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGE04686.1 - 0.00061 19.6 0.1 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain Transglut_core2 PF13369.6 EGE04686.1 - 0.065 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily MIP PF00230.20 EGE04688.1 - 1e-44 153.0 12.6 1.3e-44 152.7 12.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein HDA2-3 PF11496.8 EGE04689.1 - 8.1e-37 127.0 1.1 6.3e-18 65.0 0.0 2.8 3 1 1 4 4 4 2 Class II histone deacetylase complex subunits 2 and 3 DUF745 PF05335.13 EGE04689.1 - 0.0021 17.8 21.0 0.0094 15.7 6.7 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF745) Med9 PF07544.13 EGE04689.1 - 1.1 9.4 21.1 0.21 11.7 1.3 4.0 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 EGE04689.1 - 5 6.4 33.2 3.3 7.0 3.3 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FMO-like PF00743.19 EGE04690.1 - 1.1e-36 126.5 0.0 1.6e-22 79.7 0.0 2.6 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE04690.1 - 3.1e-11 43.1 0.0 4.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE04690.1 - 2.4e-06 27.0 0.0 4.6e-06 26.1 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE04690.1 - 2.6e-05 23.5 0.0 0.00012 21.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DUF1681 PF07933.14 EGE04693.1 - 2.7e-51 173.1 0.0 5e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CPSF100_C PF13299.6 EGE04693.1 - 0.77 9.9 3.7 1.1 9.4 0.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAXIP1_C PF15364.6 EGE04693.1 - 5.9 7.2 13.0 0.87 9.9 5.0 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein IF-2B PF01008.17 EGE04694.1 - 6.5e-51 173.2 0.0 3.1e-50 171.0 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 EGE04694.1 - 0.0087 16.0 0.0 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Nuf2 PF03800.14 EGE04695.1 - 5.3e-41 140.0 0.1 1.7e-40 138.3 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EGE04695.1 - 9.5e-31 106.3 17.0 9.5e-31 106.3 17.0 4.5 4 1 0 4 4 4 1 Designed helical repeat protein 10 domain Syntaxin-6_N PF09177.11 EGE04695.1 - 0.46 11.1 34.5 0.096 13.3 1.8 4.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EGE04695.1 - 0.82 8.5 54.3 3.7 6.3 25.7 3.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 EGE04695.1 - 1.1 9.7 23.5 0.56 10.6 1.1 5.3 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 EGE04695.1 - 5.1 6.5 44.9 0.16 11.5 20.0 3.0 1 1 2 3 3 3 0 Leucine zipper VSG_B PF13206.6 EGE04695.1 - 5.2 6.2 32.5 1.8 7.7 0.0 3.1 1 1 2 3 3 3 0 Trypanosomal VSG domain YvrJ PF12841.7 EGE04695.1 - 6.4 6.4 5.8 31 4.2 0.0 4.0 4 0 0 4 4 4 0 YvrJ protein family Nha1_C PF08619.10 EGE04696.1 - 0.00056 19.3 2.0 0.00066 19.0 2.0 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Eapp_C PF10238.9 EGE04696.1 - 0.0021 18.1 0.7 0.0025 17.9 0.7 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Pox_Ag35 PF03286.14 EGE04696.1 - 0.013 15.3 3.3 0.018 14.8 3.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2126 PF09899.9 EGE04696.1 - 0.013 13.6 0.5 0.018 13.1 0.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RPA43_OB PF17875.1 EGE04696.1 - 0.02 15.5 0.7 0.032 14.9 0.7 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RXT2_N PF08595.11 EGE04696.1 - 0.062 13.3 5.6 0.12 12.4 5.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Zip PF02535.22 EGE04696.1 - 0.076 12.2 0.6 0.079 12.2 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter WPP PF13943.6 EGE04696.1 - 0.1 13.0 0.6 0.28 11.6 0.6 1.7 1 0 0 1 1 1 0 WPP domain DUF913 PF06025.12 EGE04696.1 - 0.11 11.5 0.5 0.15 11.0 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 EGE04696.1 - 0.12 11.8 4.1 0.17 11.2 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 EGE04696.1 - 0.14 10.9 0.8 0.15 10.8 0.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 EGE04696.1 - 0.21 11.0 7.4 0.26 10.7 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 EGE04696.1 - 0.22 9.8 7.2 0.28 9.5 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EGE04696.1 - 0.29 10.8 7.3 0.47 10.1 7.3 1.3 1 0 0 1 1 1 0 FAM176 family FYDLN_acid PF09538.10 EGE04696.1 - 0.33 11.7 8.1 0.53 11.0 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Tfb4 PF03850.14 EGE04696.1 - 0.35 10.3 1.5 0.5 9.8 1.5 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Ribosomal_60s PF00428.19 EGE04696.1 - 0.36 11.4 13.8 0.27 11.8 11.2 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF551 PF04448.12 EGE04696.1 - 0.4 11.7 3.9 6.8 7.7 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF551) Nucleo_P87 PF07267.11 EGE04696.1 - 0.4 9.5 4.5 0.54 9.1 4.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ALMT PF11744.8 EGE04696.1 - 0.54 9.0 2.1 0.7 8.6 2.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2457 PF10446.9 EGE04696.1 - 0.56 9.3 15.0 0.75 8.9 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 EGE04696.1 - 0.63 9.2 5.2 0.9 8.7 5.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 EGE04696.1 - 0.67 9.9 6.4 1.1 9.2 6.4 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EGE04696.1 - 0.67 8.1 10.6 1 7.5 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGE04696.1 - 0.69 9.2 11.5 0.97 8.7 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGE04696.1 - 0.97 7.5 11.9 1.2 7.1 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFB6 PF17110.5 EGE04696.1 - 1.2 8.8 4.3 2.1 8.1 4.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH V_ATPase_I PF01496.19 EGE04696.1 - 3.4 5.4 5.3 4.3 5.1 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Astro_capsid_p PF12226.8 EGE04696.1 - 3.6 6.6 9.8 4.7 6.3 9.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cytomega_UL84 PF06284.11 EGE04696.1 - 5.2 5.4 5.0 6.7 5.0 5.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Adaptin_N PF01602.20 EGE04697.1 - 6e-97 325.4 0.0 7.1e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGE04697.1 - 2.2e-16 60.3 0.0 6.5e-14 52.3 0.0 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGE04697.1 - 1.3e-09 38.3 2.2 0.0007 19.9 0.0 4.6 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 EGE04697.1 - 6e-07 29.2 0.5 0.15 12.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat SPO22 PF08631.10 EGE04697.1 - 0.0011 18.5 0.7 0.37 10.2 0.1 3.2 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Cohesin_HEAT PF12765.7 EGE04697.1 - 0.0084 16.4 0.7 1.1 9.7 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EGE04697.1 - 0.11 12.3 1.4 76 3.1 0.0 4.0 5 0 0 5 5 5 0 VHS domain CENP-B_dimeris PF09026.10 EGE04697.1 - 0.27 11.6 0.1 0.27 11.6 0.1 4.5 3 1 0 3 3 3 0 Centromere protein B dimerisation domain Arm PF00514.23 EGE04697.1 - 0.33 11.0 1.8 6.3 7.0 0.2 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Lin-8 PF03353.15 EGE04698.1 - 6.2 6.3 8.9 10 5.6 8.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-CCHC PF00098.23 EGE04698.1 - 8 6.7 11.7 0.041 14.0 2.8 1.9 2 0 0 2 2 2 0 Zinc knuckle Metallophos PF00149.28 EGE04699.1 - 5e-37 128.4 0.3 6.9e-37 127.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.17 EGE04700.1 - 6.9e-65 218.5 0.2 7.5e-65 218.3 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor GFA PF04828.14 EGE04701.1 - 4.7e-05 23.6 0.4 4.7e-05 23.6 0.4 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EGE04701.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.6 3 0 0 3 3 3 1 Nudix N-terminal zf-NADH-PPase PF09297.11 EGE04701.1 - 0.0035 17.0 0.1 0.0035 17.0 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.13 EGE04701.1 - 0.12 12.2 1.7 0.14 11.9 0.5 1.7 2 0 0 2 2 2 0 CSL zinc finger DUF4746 PF15928.5 EGE04702.1 - 0.0087 15.5 6.5 0.0087 15.5 6.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4746) KilA-N PF04383.13 EGE04702.1 - 0.19 11.6 0.7 1.4 8.8 0.0 2.6 2 1 0 2 2 2 0 KilA-N domain RF-1 PF00472.20 EGE04702.1 - 6.6 6.7 10.2 2.7 7.9 2.3 2.4 2 0 0 2 2 2 0 RF-1 domain CLP1_P PF16575.5 EGE04703.1 - 2.5e-34 118.7 0.0 2.3e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EGE04703.1 - 7.4e-33 112.6 0.0 1.4e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EGE04703.1 - 2.2e-24 86.1 0.0 5.5e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EGE04703.1 - 0.00025 20.9 0.0 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGE04703.1 - 0.0083 16.2 0.0 0.053 13.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGE04703.1 - 0.036 14.6 0.0 0.15 12.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EGE04703.1 - 0.047 13.4 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGE04703.1 - 0.2 11.1 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_zinc_N PF00107.26 EGE04705.1 - 3.3e-26 91.8 0.1 6.6e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE04705.1 - 3.5e-23 83.1 0.0 6.6e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE04705.1 - 6.3e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGE04705.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Arb1 PF09692.10 EGE04706.1 - 8.7e-143 476.3 0.1 1.1e-142 476.0 0.1 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PG_binding_1 PF01471.18 EGE04706.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain IPK PF03770.16 EGE04707.1 - 2e-60 204.0 0.0 2.5e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DNA_pol_phi PF04931.13 EGE04707.1 - 0.13 10.3 3.2 0.18 9.9 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_S19 PF00203.21 EGE04708.1 - 4.6e-25 87.3 0.0 5.8e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 EGE04709.1 - 3.5e-22 78.1 0.1 6e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EGE04709.1 - 6.1 7.5 6.5 32 5.2 6.5 2.2 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TRF PF08558.10 EGE04710.1 - 6e-81 271.6 0.5 1.2e-80 270.6 0.5 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EGE04710.1 - 0.0005 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rrn6 PF10214.9 EGE04710.1 - 3.1 6.2 27.1 0.064 11.8 19.0 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor His_Phos_2 PF00328.22 EGE04711.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 EGE04713.1 - 2.2e-29 102.5 54.5 7.2e-26 90.9 56.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily UL41A PF17591.2 EGE04713.1 - 0.0034 17.5 3.1 0.0046 17.0 0.8 2.5 2 0 0 2 2 2 1 Herpesvirus UL41A PepSY_TM_like_2 PF16357.5 EGE04713.1 - 0.07 13.1 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF4006 PF13179.6 EGE04713.1 - 0.079 12.9 0.1 0.44 10.5 0.1 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF4267 PF14087.6 EGE04715.1 - 1.8e-26 92.4 5.2 2.2e-26 92.1 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Pkinase PF00069.25 EGE04716.1 - 1.2e-74 251.1 0.0 1.6e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04716.1 - 1.2e-31 110.0 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGE04716.1 - 2.7e-06 26.9 0.1 0.71 9.1 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EGE04716.1 - 0.013 14.3 0.7 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGE04716.1 - 0.035 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE04716.1 - 0.072 13.0 0.0 3 7.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family NOA36 PF06524.12 EGE04717.1 - 0.16 11.3 5.6 0.18 11.1 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein Roughex PF06020.11 EGE04717.1 - 0.16 11.0 4.7 0.18 10.9 4.7 1.0 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EGE04717.1 - 4.2 5.5 6.2 4.2 5.5 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 EGE04717.1 - 8.1 5.2 7.1 9.1 5.0 7.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DASH_Dad3 PF08656.10 EGE04718.1 - 1.7e-29 101.7 2.1 2e-29 101.5 2.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.10 EGE04718.1 - 0.058 12.9 0.1 0.06 12.8 0.1 1.1 1 0 0 1 1 1 0 Imelysin SopE_GEF PF07487.13 EGE04718.1 - 0.19 11.8 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 SopE GEF domain Ribosomal_S5_C PF03719.15 EGE04719.1 - 1.9e-24 84.9 0.1 2.8e-23 81.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EGE04719.1 - 2.2e-21 75.6 0.2 4.8e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 EGE04722.1 - 2.9e-16 59.4 0.1 3.3e-14 52.7 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGE04722.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04722.1 - 7.6e-05 23.3 0.1 0.00032 21.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGE04722.1 - 0.00032 20.3 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EGE04722.1 - 0.0013 19.3 0.1 0.021 15.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGE04722.1 - 0.029 13.8 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.19 EGE04723.1 - 8.5e-88 294.7 0.0 8.6e-86 288.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGE04723.1 - 0.00014 20.8 0.1 0.0046 15.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGE04723.1 - 0.0052 17.2 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA Asparaginase_2 PF01112.18 EGE04724.1 - 3.9e-46 157.5 7.0 1.8e-30 106.1 0.0 2.2 2 0 0 2 2 2 2 Asparaginase SasG_E PF17041.5 EGE04724.1 - 0.0056 16.6 0.2 0.015 15.3 0.2 1.7 1 0 0 1 1 1 1 E domain PEHE PF15275.6 EGE04724.1 - 0.068 13.8 0.5 0.17 12.5 0.3 1.6 1 1 0 1 1 1 0 PEHE domain Tfb4 PF03850.14 EGE04725.1 - 1.4e-109 365.9 0.0 1.8e-109 365.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 REF PF05755.12 EGE04725.1 - 0.18 11.6 0.7 0.32 10.8 0.7 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) UNC45-central PF11701.8 EGE04726.1 - 2.1e-45 154.4 4.3 5.5e-45 153.1 1.2 3.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.9 EGE04726.1 - 0.0005 20.0 0.0 1.4 8.9 0.0 2.9 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EGE04726.1 - 0.048 13.7 12.9 26 5.0 0.0 7.9 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat Peptidase_S9 PF00326.21 EGE04726.1 - 0.21 11.1 0.0 0.49 9.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Trp_halogenase PF04820.14 EGE04727.1 - 1.3e-28 100.1 0.2 7.7e-14 51.4 0.0 2.8 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EGE04727.1 - 1.9e-09 37.3 0.0 3.9e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE04727.1 - 3.7e-05 23.9 0.2 3.7e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGE04727.1 - 0.00047 19.6 0.5 0.0014 18.0 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE04727.1 - 0.0006 19.1 0.1 0.001 18.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGE04727.1 - 0.0013 17.9 0.1 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGE04727.1 - 0.0031 16.3 0.1 0.006 15.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGE04727.1 - 0.0084 15.2 0.7 0.03 13.4 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 EGE04727.1 - 0.012 15.9 0.1 4.2 7.7 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 EGE04727.1 - 0.022 14.4 0.7 0.044 13.4 0.4 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase p450 PF00067.22 EGE04728.1 - 5.8e-27 94.5 0.0 7.9e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGE04729.1 - 3.1e-71 240.5 0.0 5.6e-71 239.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 UPF0203 PF05254.12 EGE04729.1 - 0.14 12.4 0.5 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Zn_clus PF00172.18 EGE04730.1 - 3.1e-07 30.4 6.0 6.8e-07 29.3 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIG2_2 PF13772.6 EGE04731.1 - 6.2e-05 23.3 0.0 9.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family MFS_1 PF07690.16 EGE04732.1 - 1.5e-44 152.4 47.6 1.5e-44 152.4 47.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE04732.1 - 1.7e-19 69.7 14.9 3.6e-19 68.6 14.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE04732.1 - 7.9e-12 44.8 10.3 7.9e-12 44.8 10.3 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF1422 PF07226.11 EGE04732.1 - 0.0096 15.9 0.4 0.0096 15.9 0.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1422) PsbY PF06298.11 EGE04732.1 - 0.022 14.6 0.3 0.022 14.6 0.3 1.9 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) ABC_tran PF00005.27 EGE04733.1 - 4.4e-32 111.5 0.0 8.4e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGE04733.1 - 3.8e-25 89.1 15.9 3.8e-25 89.1 15.9 2.0 2 1 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EGE04733.1 - 2.6e-07 30.3 0.0 0.00043 19.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE04733.1 - 0.00084 19.0 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGE04733.1 - 0.0011 19.2 0.0 0.0047 17.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGE04733.1 - 0.0027 18.1 0.2 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 EGE04733.1 - 0.011 16.0 0.2 0.25 11.6 0.2 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGE04733.1 - 0.014 15.9 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGE04733.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGE04733.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 EGE04733.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 EGE04733.1 - 0.049 13.4 0.1 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGE04733.1 - 0.061 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGE04733.1 - 0.065 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGE04733.1 - 0.073 13.2 0.3 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain TmoB PF06234.12 EGE04733.1 - 0.092 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) Zeta_toxin PF06414.12 EGE04733.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Aminotran_1_2 PF00155.21 EGE04734.1 - 3.1e-41 141.8 0.0 3.6e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1382 PF07131.11 EGE04734.1 - 0.21 11.6 0.9 1.8 8.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1382) MBOAT_2 PF13813.6 EGE04735.1 - 5.8e-22 77.8 1.1 1e-21 77.0 1.1 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.22 EGE04736.1 - 7.4e-36 123.9 0.0 1e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EutC PF05985.11 EGE04736.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Pyr_redox_2 PF07992.14 EGE04737.1 - 1.2e-18 67.4 0.0 2.1e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE04737.1 - 0.00018 21.5 0.4 1.2 9.1 0.3 3.5 2 2 2 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 EGE04737.1 - 0.00029 20.6 0.7 0.0067 16.1 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE04737.1 - 0.001 18.2 0.1 0.0023 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE04737.1 - 0.0014 18.8 0.5 0.003 17.7 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGE04737.1 - 0.0023 17.2 0.4 2.1 7.5 0.2 3.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE04737.1 - 0.03 13.0 0.1 0.17 10.6 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EGE04737.1 - 0.047 13.0 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGE04737.1 - 0.052 12.6 0.4 0.098 11.7 0.4 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EGE04739.1 - 1.8e-10 40.5 0.0 4.1e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE04739.1 - 0.00028 20.3 0.1 0.0016 17.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE04739.1 - 0.0006 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EGE04739.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE04739.1 - 0.0024 18.0 0.1 0.0052 17.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGE04739.1 - 0.0086 14.8 0.2 0.048 12.4 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGE04739.1 - 0.069 12.5 3.0 0.091 12.1 2.6 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGE04739.1 - 0.081 12.0 0.1 0.29 10.2 0.1 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EGE04739.1 - 0.13 12.8 0.0 0.38 11.2 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 EGE04739.1 - 0.17 11.1 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGE04739.1 - 0.2 11.6 4.2 1.4 8.9 0.9 2.5 1 1 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EGE04739.1 - 0.7 9.4 4.1 0.86 9.1 1.6 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE04740.1 - 4.8e-15 55.6 0.0 1.8e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGE04740.1 - 9.6e-05 21.6 0.2 0.00036 19.8 0.1 1.8 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGE04740.1 - 0.0001 22.4 0.1 0.00033 20.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGE04740.1 - 0.0002 21.4 0.1 3 7.8 0.0 3.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGE04740.1 - 0.0003 19.8 0.0 0.00041 19.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 EGE04740.1 - 0.00081 18.2 0.0 0.0048 15.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGE04740.1 - 0.0011 18.6 0.4 0.0035 17.0 0.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE04740.1 - 0.004 16.3 0.2 0.008 15.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EGE04740.1 - 0.0049 16.2 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGE04740.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE04740.1 - 0.024 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGE04740.1 - 0.053 12.9 0.1 0.053 12.9 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGE04740.1 - 0.055 12.5 0.0 0.29 10.1 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGE04740.1 - 0.13 11.5 1.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_2 PF00891.18 EGE04741.1 - 1.1e-30 106.5 0.0 3.3e-30 105.0 0.0 1.8 1 1 1 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGE04741.1 - 3.4e-05 23.7 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 EGE04741.1 - 0.00016 21.6 0.5 0.00052 20.0 0.2 2.1 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_23 PF13489.6 EGE04741.1 - 0.00078 19.3 0.0 0.0033 17.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Rrf2 PF02082.20 EGE04741.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_12 PF08242.12 EGE04741.1 - 0.072 13.8 0.0 0.34 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04741.1 - 0.16 12.7 0.0 0.82 10.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain GST_C PF00043.25 EGE04742.1 - 2.8e-07 30.7 0.0 4.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE04742.1 - 2.2e-06 27.8 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGE04742.1 - 5.1e-05 23.5 0.1 0.0001 22.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE04742.1 - 6.6e-05 23.2 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE04742.1 - 0.00016 21.6 0.1 0.0003 20.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE04742.1 - 0.0047 17.2 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EGE04742.1 - 0.068 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein p450 PF00067.22 EGE04743.1 - 8.7e-50 169.8 0.0 1.2e-49 169.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.21 EGE04744.1 - 7.3e-102 340.8 0.0 8.5e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) HAS-barrel PF09378.10 EGE04744.1 - 0.061 13.5 0.0 14 5.9 0.1 2.3 2 0 0 2 2 2 0 HAS barrel domain DUF2113 PF09886.9 EGE04744.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) Stig1 PF04885.13 EGE04745.1 - 1.1e-15 58.4 74.7 2.6e-05 24.7 15.5 4.3 1 1 3 4 4 4 4 Stigma-specific protein, Stig1 AMP-binding PF00501.28 EGE04746.1 - 1.1e-76 258.1 0.0 1.7e-76 257.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGE04746.1 - 4.8e-51 173.9 0.0 5.6e-27 94.5 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE04746.1 - 3.2e-18 65.8 0.2 2.3e-08 34.3 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE04746.1 - 0.017 16.1 0.1 0.045 14.7 0.1 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Transp_cyt_pur PF02133.15 EGE04747.1 - 5.8e-81 272.5 31.8 2.6e-80 270.4 31.8 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GFO_IDH_MocA PF01408.22 EGE04748.1 - 3.6e-14 53.6 0.0 5.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGE04748.1 - 1.5e-05 25.0 0.0 7e-05 22.8 0.0 2.2 2 1 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EGE04748.1 - 0.0065 17.1 0.2 0.012 16.2 0.2 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1489 PF07370.11 EGE04748.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) ADSL_C PF10397.9 EGE04748.1 - 0.17 12.5 0.3 1.3 9.7 0.3 2.1 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Methyltransf_2 PF00891.18 EGE04749.1 - 1e-27 96.8 0.0 2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGE04749.1 - 0.00065 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 EGE04749.1 - 0.026 14.9 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PDZ_3 PF17815.1 EGE04749.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 PDZ domain GDPD PF03009.17 EGE04752.1 - 2.8e-68 230.5 0.0 6.2e-68 229.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EGE04752.1 - 4.7e-25 88.0 0.2 2.4e-07 31.3 0.5 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE04752.1 - 9.3e-24 83.5 0.5 2.4e-08 34.4 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGE04752.1 - 7.9e-18 64.0 3.4 0.0016 18.8 0.0 6.1 4 1 0 4 4 4 4 Ankyrin repeat SPX PF03105.19 EGE04752.1 - 8e-17 62.2 21.3 3.6e-11 43.6 0.2 4.3 3 2 1 4 4 4 3 SPX domain Ank_5 PF13857.6 EGE04752.1 - 1.3e-14 54.1 0.1 1.5e-05 25.1 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04752.1 - 8.4e-14 50.3 0.8 0.032 14.8 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat TAT_signal PF10518.9 EGE04752.1 - 0.038 13.8 0.1 0.85 9.6 0.1 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PRMT5 PF05185.16 EGE04753.1 - 2.8e-65 219.4 0.0 4e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EGE04753.1 - 2.2e-39 135.2 0.2 5.1e-39 134.0 0.2 1.6 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 EGE04753.1 - 1.1e-34 119.8 0.0 3.9e-31 108.2 0.0 2.3 1 1 1 2 2 2 2 PRMT5 TIM barrel domain OB_NTP_bind PF07717.16 EGE04754.1 - 6.2e-21 74.6 0.0 1.7e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGE04754.1 - 6.1e-19 68.3 0.0 1.6e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGE04754.1 - 3e-10 40.4 0.0 7.7e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE04754.1 - 3.7e-07 30.1 0.1 6.5e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE04754.1 - 2.9e-05 24.3 0.0 9.9e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGE04754.1 - 0.00027 20.6 0.1 0.00075 19.2 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EGE04754.1 - 0.0024 18.2 0.1 0.0049 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EGE04754.1 - 0.0025 17.8 0.1 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EGE04754.1 - 0.0042 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGE04754.1 - 0.042 14.4 0.0 0.077 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGE04754.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EGE04754.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) EF-hand_6 PF13405.6 EGE04756.1 - 6.2e-09 35.1 0.7 0.00031 20.4 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGE04756.1 - 1.8e-05 25.1 0.5 9.1e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGE04756.1 - 0.0074 15.8 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 EF hand Met_10 PF02475.16 EGE04757.1 - 6.7e-05 22.7 0.1 0.00035 20.4 0.0 2.2 2 1 0 2 2 2 1 Met-10+ like-protein HpaP PF09483.10 EGE04758.1 - 0.0092 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III secretion protein (HpaP) MFS_1 PF07690.16 EGE04760.1 - 1.6e-20 73.3 35.0 5.1e-17 61.8 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 EGE04761.1 - 3.7e-05 23.9 0.0 0.057 13.7 0.0 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE04761.1 - 8.4e-05 23.3 0.0 0.048 14.5 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGE04761.1 - 0.0095 15.0 0.0 0.75 8.8 0.0 2.3 2 0 0 2 2 2 2 Coatomer WD associated region CNH PF00780.22 EGE04761.1 - 0.01 15.5 0.1 1.9 8.0 0.1 3.2 3 1 0 3 3 3 0 CNH domain Hira PF07569.11 EGE04761.1 - 0.033 13.9 0.1 2.6 7.7 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split Big_7 PF17957.1 EGE04761.1 - 0.1 13.4 0.4 0.83 10.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain LCM PF04072.14 EGE04762.1 - 4.2e-19 69.2 0.0 6.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EGE04762.1 - 2.5e-14 53.0 4.2 1.3e-07 31.5 0.0 4.4 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EGE04762.1 - 4.4e-07 30.0 2.5 0.0034 17.6 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGE04762.1 - 1.3e-05 25.0 0.6 0.027 14.5 0.0 3.7 4 0 0 4 4 4 2 Kelch motif DSPc PF00782.20 EGE04763.1 - 1.1e-26 93.2 0.0 2.4e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE04763.1 - 0.0039 16.8 0.0 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RSN1_TM PF13967.6 EGE04764.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Mlh1_C PF16413.5 EGE04765.1 - 3.5e-104 348.0 0.0 4.6e-104 347.6 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus HATPase_c_3 PF13589.6 EGE04765.1 - 2.9e-13 49.8 0.0 5.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGE04765.1 - 1e-06 29.2 0.0 5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YafO_toxin PF13957.6 EGE04766.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system RPN1_RPN2_N PF17781.1 EGE04767.1 - 4.5e-118 394.1 5.5 8.3e-118 393.3 5.5 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGE04767.1 - 4.4e-29 100.3 0.0 8.2e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGE04767.1 - 1.1e-20 72.9 12.9 7.3e-05 23.0 0.1 8.2 7 0 0 7 7 7 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGE04767.1 - 0.0028 18.0 1.2 3.9 7.9 0.0 4.2 5 2 1 6 6 6 2 HEAT repeats EMC3_TMCO1 PF01956.16 EGE04767.1 - 0.15 11.8 0.1 19 4.9 0.0 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TetR_C_35 PF18556.1 EGE04768.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Cyclin PF08613.11 EGE04770.1 - 1.3e-12 48.4 0.7 1.3e-12 48.4 0.7 1.9 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGE04770.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RNA_pol_Rpb2_4 PF04566.13 EGE04771.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Pyr_redox_2 PF07992.14 EGE04776.1 - 1.9e-52 178.3 0.1 2.7e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE04776.1 - 1.4e-10 41.6 0.0 3.4e-09 37.1 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE04776.1 - 0.0033 16.7 0.1 3.1 7.0 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EGE04776.1 - 0.028 14.1 1.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF4381 PF14316.6 EGE04777.1 - 0.057 13.7 0.1 0.093 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.10 EGE04777.1 - 0.06 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2681 PF10883.8 EGE04777.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ASFV_J13L PF05568.11 EGE04777.1 - 0.73 9.6 2.8 12 5.6 0.7 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein Acetyltransf_7 PF13508.7 EGE04778.1 - 5.8e-10 39.5 0.1 1.1e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGE04778.1 - 7.2e-10 38.9 0.0 1.1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE04778.1 - 1.3e-09 38.3 0.0 2.7e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGE04778.1 - 1.4e-05 25.2 0.0 0.016 15.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE04778.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGE04778.1 - 0.0022 18.1 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.22 EGE04779.1 - 5.5e-15 56.0 0.1 2.8e-14 53.7 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGE04779.1 - 2.2e-06 27.8 0.0 0.0014 18.7 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.22 EGE04782.1 - 3.6e-59 196.5 0.0 1.2e-20 73.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE04782.1 - 3.2e-08 33.2 0.0 0.00017 21.2 0.0 2.8 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE04782.1 - 2.3e-07 30.5 0.0 0.0089 15.9 0.0 3.5 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGE04782.1 - 7.5e-05 22.7 0.1 3.6 7.7 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 EGE04782.1 - 0.0006 20.0 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 2 RRM-like domain Cas_Cas2CT1978 PF09707.10 EGE04782.1 - 0.0016 18.4 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM PF05172.13 EGE04782.1 - 0.0017 18.3 0.0 15 5.7 0.0 3.3 2 1 1 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGE04782.1 - 0.013 15.6 0.0 11 6.2 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif SET_assoc PF11767.8 EGE04782.1 - 0.16 11.6 0.0 26 4.5 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated PIG-Y PF15159.6 EGE04783.1 - 9.1e-24 84.2 8.6 1.5e-23 83.5 8.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 EGE04783.1 - 0.4 11.2 4.5 3.9 8.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) GATase_4 PF13230.6 EGE04784.1 - 1.5e-14 53.6 0.0 9.9e-13 47.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGE04784.1 - 4.6e-07 30.1 0.0 7.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Kazal_2 PF07648.15 EGE04785.1 - 4.5e-09 36.3 4.0 6.6e-09 35.8 4.0 1.3 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 EGE04785.1 - 3.8e-07 30.0 2.1 5.6e-07 29.5 2.1 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain GDC-P PF02347.16 EGE04785.1 - 0.21 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dynamin_N PF00350.23 EGE04786.1 - 1.1e-44 152.4 0.0 2.6e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGE04786.1 - 2.3e-12 46.8 0.0 5.4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EGE04786.1 - 3.2e-05 24.0 0.0 8.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE04786.1 - 0.0028 18.0 0.6 0.062 13.7 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EGE04786.1 - 0.011 15.5 0.6 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EGE04786.1 - 0.036 13.9 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ribosomal_S6 PF01250.17 EGE04787.1 - 5.7e-23 81.0 0.0 7.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.19 EGE04788.1 - 3.7e-40 136.6 1.2 4.3e-40 136.4 1.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGE04788.1 - 0.00097 19.1 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EGE04788.1 - 0.031 14.1 0.9 0.031 14.1 0.9 1.9 2 1 0 2 2 2 0 Biotin-requiring enzyme zf-rbx1 PF12678.7 EGE04789.1 - 2e-09 37.6 3.4 5.7e-09 36.1 3.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGE04789.1 - 3.7e-08 33.6 8.0 1.2e-07 32.0 4.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE04789.1 - 2e-07 30.7 7.0 5.2e-07 29.4 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE04789.1 - 1.1e-06 28.4 3.5 3.3e-06 26.9 3.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE04789.1 - 5.6e-06 26.1 2.2 9.5e-06 25.4 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE04789.1 - 0.00012 21.8 1.8 0.00012 21.8 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGE04789.1 - 0.0002 21.2 1.4 0.0002 21.2 1.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGE04789.1 - 0.00043 20.3 7.4 0.0011 18.9 2.8 3.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGE04789.1 - 0.0017 18.1 10.1 0.0025 17.5 0.8 3.3 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGE04789.1 - 0.013 15.1 1.6 0.013 15.1 1.6 1.6 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGE04789.1 - 0.025 14.6 3.7 0.057 13.5 3.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 EGE04789.1 - 0.052 11.4 1.3 0.096 10.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) PQ-loop PF04193.14 EGE04789.1 - 0.76 9.6 8.1 2.1 8.2 2.4 2.8 2 0 0 2 2 2 0 PQ loop repeat FANCL_C PF11793.8 EGE04789.1 - 1.8 8.8 5.8 5 7.4 3.5 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 EGE04789.1 - 3.9 7.7 6.9 0.41 10.8 2.0 1.8 2 0 0 2 2 2 0 RING-variant domain zf-C3H2C3 PF17122.5 EGE04789.1 - 6 7.0 4.8 2.6 8.2 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger Cation_efflux PF01545.21 EGE04790.1 - 2.8e-14 53.3 11.7 3.7e-14 52.9 11.7 1.1 1 0 0 1 1 1 1 Cation efflux family DnaB_2 PF07261.11 EGE04791.1 - 0.05 13.4 0.0 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Replication initiation and membrane attachment COMPASS-Shg1 PF05205.12 EGE04793.1 - 1.4e-26 93.1 0.1 1.4e-26 93.1 0.1 2.2 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF4E PF01652.18 EGE04794.1 - 1.3e-29 103.1 0.2 1.6e-29 102.7 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2517 PF10725.9 EGE04794.1 - 0.067 13.0 0.1 2.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2517) 2Fe-2S_thioredx PF01257.19 EGE04794.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF4598 PF15370.6 EGE04795.1 - 5.4e-28 97.7 5.1 5.4e-28 97.7 5.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) CENP-B_dimeris PF09026.10 EGE04795.1 - 2.3 8.7 10.7 0.18 12.2 2.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GDA1_CD39 PF01150.17 EGE04796.1 - 2e-101 339.7 0.0 2.5e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IF3_C PF00707.22 EGE04797.1 - 3.7e-10 39.6 0.8 5.9e-10 39.0 0.8 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EGE04797.1 - 8.5e-09 35.6 1.5 2.4e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EGE04797.1 - 2.1e-06 27.5 2.0 1.7e-05 24.5 1.8 2.0 1 1 1 2 2 2 1 Mitochondrial translation initiation factor GTP_EFTU PF00009.27 EGE04798.1 - 1.1e-57 194.8 0.0 1.5e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGE04798.1 - 2.3e-21 76.2 0.0 4.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGE04798.1 - 2.6e-17 63.0 1.7 6.3e-17 61.7 1.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGE04798.1 - 2.2e-05 24.5 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EGE04798.1 - 0.016 14.8 0.2 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EGE04798.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EGE04798.1 - 0.041 13.6 0.2 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SCAB-ABD PF16711.5 EGE04798.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Radical_SAM PF04055.21 EGE04799.1 - 5e-15 56.3 0.1 2.7e-14 53.9 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGE04799.1 - 1.3e-07 32.0 0.3 2.8e-07 30.9 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGE04799.1 - 5.1e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3222 PF11519.8 EGE04801.1 - 0.18 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3222) bZIP_1 PF00170.21 EGE04802.1 - 7.2e-05 22.8 12.2 0.00014 21.9 12.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 EGE04802.1 - 0.031 14.9 0.2 0.11 13.2 0.1 1.9 1 1 1 2 2 2 0 Initiation control protein YabA DUF2205 PF10224.9 EGE04802.1 - 0.077 13.0 5.9 0.18 11.8 5.9 1.6 1 0 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 EGE04802.1 - 0.12 12.2 1.1 0.24 11.2 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator GvpL_GvpF PF06386.11 EGE04802.1 - 0.41 10.5 5.8 0.56 10.1 5.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF KfrA_N PF11740.8 EGE04802.1 - 1.7 9.3 8.2 3.1 8.5 8.2 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term ABM PF03992.16 EGE04803.1 - 0.083 13.0 0.1 0.7 10.0 0.0 2.4 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 EGE04804.1 - 2.8e-40 138.3 56.7 2.8e-40 138.3 56.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE04804.1 - 2.5e-16 59.2 26.9 3.2e-16 58.9 26.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 EGE04805.1 - 0.00013 22.1 8.6 0.00013 22.1 8.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_c3_2 PF14537.6 EGE04805.1 - 2.6 8.6 7.6 20 5.7 0.1 2.6 2 0 0 2 2 2 0 Cytochrome c3 Paired_CXXCH_1 PF09699.10 EGE04805.1 - 6.1 6.7 11.6 6.4 6.6 0.4 3.4 2 1 2 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) MFS_1 PF07690.16 EGE04807.1 - 7.6e-31 107.3 43.6 3.3e-30 105.2 43.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04807.1 - 2e-10 40.1 11.8 2e-10 40.1 11.8 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EGE04807.1 - 0.00027 19.3 0.8 0.00071 18.0 0.8 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UL42 PF17638.2 EGE04807.1 - 0.17 11.9 1.8 0.68 9.9 0.0 2.7 3 0 0 3 3 3 0 HCMV UL42 RHD3 PF05879.12 EGE04808.1 - 2.3e-122 409.7 8.1 3.8e-54 184.1 0.3 3.0 1 1 2 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 EGE04808.1 - 7.1e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EGE04808.1 - 0.00012 22.3 0.0 0.00034 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain GBP PF02263.19 EGE04808.1 - 0.00031 20.1 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Septin PF00735.18 EGE04808.1 - 0.00041 19.7 0.2 0.0009 18.6 0.2 1.5 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGE04808.1 - 0.00057 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DIM1 PF02966.16 EGE04809.1 - 2.2e-68 228.1 0.1 2.6e-68 227.9 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGE04809.1 - 0.0047 16.9 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin 4HBT_2 PF13279.6 EGE04810.1 - 3e-05 24.5 0.0 0.00022 21.7 0.1 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.13 EGE04811.1 - 2e-06 27.9 0.2 2e-06 27.9 0.2 2.0 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Med26 PF08711.11 EGE04812.1 - 1.9e-09 37.4 0.0 4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.9 EGE04813.1 - 1e-18 67.0 0.1 1.1e-18 66.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 EGE04814.1 - 1.1e-41 142.2 0.3 1.1e-41 142.2 0.3 3.0 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EGE04814.1 - 9.4e-13 47.5 1.3 1.6e-12 46.7 1.3 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EGE04814.1 - 1.4e-08 35.5 36.8 1.4e-08 35.5 36.8 2.5 1 1 1 2 2 2 1 Nucleoporin FG repeat region Fib_alpha PF08702.10 EGE04814.1 - 0.0027 17.9 0.7 0.0027 17.9 0.7 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family AAA PF00004.29 EGE04815.1 - 5.1e-16 59.3 0.0 1.4e-15 57.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EGE04815.1 - 1.6e-12 47.4 1.0 9.6e-12 44.9 0.5 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 EGE04815.1 - 2.3e-12 47.6 0.0 1.8e-10 41.5 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGE04815.1 - 2.7e-09 37.4 0.0 1.1e-08 35.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGE04815.1 - 0.00073 19.9 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE04815.1 - 0.0011 18.9 1.4 0.0017 18.2 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EGE04815.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGE04815.1 - 0.0051 16.1 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 KAP family P-loop domain NACHT PF05729.12 EGE04815.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGE04815.1 - 0.018 15.4 0.0 0.098 13.1 0.0 2.3 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 EGE04815.1 - 0.021 14.8 0.0 0.3 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EGE04815.1 - 0.021 15.0 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EGE04815.1 - 0.029 13.4 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EGE04815.1 - 0.04 13.4 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region BAH PF01426.18 EGE04815.1 - 0.04 13.8 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.14 EGE04815.1 - 0.075 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 EGE04815.1 - 0.076 12.2 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) BLM_N PF16202.5 EGE04815.1 - 0.1 11.7 0.1 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 N-terminal region of Bloom syndrome protein S6OS1 PF15676.5 EGE04815.1 - 0.13 10.7 0.1 0.24 9.8 0.1 1.3 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family WD40 PF00400.32 EGE04816.1 - 3.5e-42 141.6 15.5 9.8e-10 38.9 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04816.1 - 5.1e-05 23.5 0.7 1.7 9.0 0.0 4.6 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE04816.1 - 0.012 14.3 1.9 8.7 4.9 0.0 3.8 1 1 3 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EGE04816.1 - 0.24 10.7 0.0 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Ank_2 PF12796.7 EGE04817.1 - 1.6e-41 140.8 1.5 1.7e-14 54.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE04817.1 - 9.1e-33 111.9 2.7 6.2e-09 36.0 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE04817.1 - 2.8e-32 110.7 2.5 3.4e-09 37.0 0.0 4.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE04817.1 - 1.9e-27 92.2 0.3 0.00069 19.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EGE04817.1 - 7.1e-20 70.5 0.9 0.0076 16.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat TMF_TATA_bd PF12325.8 EGE04818.1 - 4.8e-40 136.4 13.4 4.8e-40 136.4 13.4 6.5 3 1 3 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGE04818.1 - 6.3e-23 80.6 19.0 6.3e-23 80.6 19.0 8.0 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EGE04818.1 - 7.9e-05 23.0 3.9 7.9e-05 23.0 3.9 5.9 2 1 3 6 6 6 1 Autophagy protein 16 (ATG16) FH2 PF02181.23 EGE04818.1 - 0.0051 16.0 1.9 0.0051 16.0 1.9 5.0 3 2 2 5 5 5 1 Formin Homology 2 Domain Muted PF14942.6 EGE04818.1 - 0.012 15.9 6.5 0.012 15.9 6.5 5.7 2 1 3 6 6 6 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.25 EGE04819.1 - 5.5e-10 39.0 0.0 1.8e-06 27.5 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE04819.1 - 5.5e-09 35.7 0.0 5.1e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase V-ATPase_H_N PF03224.14 EGE04820.1 - 1.6e-77 260.9 0.0 2.6e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGE04820.1 - 1.4e-35 121.9 0.0 5.5e-35 120.0 0.0 2.0 1 0 0 1 1 1 1 V-ATPase subunit H Apq12 PF12716.7 EGE04823.1 - 1.3e-21 76.3 11.7 1.9e-21 75.8 11.7 1.3 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis S-AdoMet_synt_M PF02772.16 EGE04824.1 - 1.2e-46 157.9 0.0 2.7e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGE04824.1 - 1.9e-44 150.4 0.8 5.7e-44 148.8 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_C PF02773.16 EGE04824.1 - 3.4e-33 114.5 2.9 3.4e-33 114.5 2.9 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain AdoMet_Synthase PF01941.19 EGE04824.1 - 0.019 13.8 0.5 0.43 9.3 0.1 2.1 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) SLD3 PF08639.10 EGE04825.1 - 5.8e-68 230.0 23.1 2.5e-40 138.8 8.8 2.6 2 1 1 3 3 3 2 DNA replication regulator SLD3 CRC_subunit PF08624.10 EGE04827.1 - 9.6e-52 175.0 0.2 1.5e-51 174.3 0.2 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.19 EGE04827.1 - 0.85 9.7 7.2 3.4 7.9 6.5 2.5 1 1 0 1 1 1 0 AT hook motif APH PF01636.23 EGE04828.1 - 1.1e-12 48.5 0.2 1.4e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE04828.1 - 0.0046 16.6 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EGE04828.1 - 0.03 13.2 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGE04828.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Homeodomain PF00046.29 EGE04830.1 - 1.5e-16 60.0 1.5 1.5e-15 56.8 2.7 2.0 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EGE04830.1 - 0.00052 19.8 1.1 0.0013 18.6 1.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF4638 PF15472.6 EGE04830.1 - 0.0094 15.7 2.6 0.015 15.0 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4638) SDP_N PF12278.8 EGE04830.1 - 3.4 7.8 10.3 8 6.6 10.3 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal MCM_bind PF09739.9 EGE04830.1 - 4.1 5.7 10.6 6.4 5.1 10.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HAD_2 PF13419.6 EGE04834.1 - 2.4e-20 73.4 0.0 3.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE04834.1 - 6.5e-10 39.7 0.2 5.9e-06 26.7 0.0 2.8 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGE04834.1 - 7e-05 23.3 0.0 0.00011 22.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE04834.1 - 0.0012 18.8 0.1 0.0031 17.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGE04834.1 - 0.0023 18.0 0.2 0.087 12.9 0.1 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 EGE04835.1 - 1.1e-24 86.3 16.8 2.7e-24 85.0 16.8 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGE04835.1 - 3.8e-18 65.6 0.3 5.5e-13 49.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE04835.1 - 4.9e-07 29.8 0.1 2.6e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EGE04835.1 - 6.9e-06 25.7 0.1 5.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGE04835.1 - 0.00012 22.2 6.2 0.68 10.0 0.2 3.9 2 2 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EGE04835.1 - 0.00057 19.5 0.4 0.54 9.8 0.2 3.3 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGE04835.1 - 0.015 14.6 0.3 0.057 12.7 0.1 1.9 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 EGE04835.1 - 0.019 14.6 0.1 0.68 9.5 0.0 2.8 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGE04835.1 - 0.02 13.9 0.1 0.044 12.7 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGE04835.1 - 0.082 13.5 0.4 0.48 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EGE04835.1 - 0.086 13.1 0.0 9.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGE04835.1 - 0.41 11.0 0.0 0.41 11.0 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.23 EGE04836.1 - 4.7e-06 26.8 0.0 9.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HNF-1_N PF04814.13 EGE04836.1 - 9.6 6.8 12.1 11 6.6 11.6 1.4 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SIR2 PF02146.17 EGE04837.1 - 3e-26 92.4 0.0 1.2e-25 90.5 0.0 1.9 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 EGE04838.1 - 4.1e-167 557.4 0.0 5e-167 557.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 EGE04838.1 - 0.0088 16.3 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L29 PF00831.23 EGE04839.1 - 9.2e-18 64.0 0.2 9.2e-18 64.0 0.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Phe_tRNA-synt_N PF02912.18 EGE04839.1 - 0.056 13.4 0.1 0.056 13.4 0.1 2.3 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Cortex-I_coil PF09304.10 EGE04839.1 - 0.27 11.4 5.5 0.33 11.2 1.3 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.18 EGE04839.1 - 0.38 10.0 2.3 0.47 9.7 2.3 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V-SNARE_C PF12352.8 EGE04840.1 - 4.8e-16 58.8 7.3 3.4e-15 56.1 0.1 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 EGE04840.1 - 0.012 14.4 6.6 0.016 13.9 6.6 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 AAA_13 PF13166.6 EGE04840.1 - 0.025 13.2 1.3 0.031 13.0 1.3 1.2 1 0 0 1 1 1 0 AAA domain NleF_casp_inhib PF16809.5 EGE04840.1 - 0.041 13.8 1.1 0.16 11.9 0.7 1.8 1 1 1 2 2 2 0 NleF caspase inhibitor Sec20 PF03908.13 EGE04840.1 - 0.051 13.5 4.4 6 6.9 0.0 3.1 2 1 0 3 3 3 0 Sec20 Phage_GPO PF05929.11 EGE04840.1 - 0.065 12.8 1.8 0.086 12.4 1.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 EGE04840.1 - 0.087 12.6 7.0 1 9.1 1.0 3.3 2 1 1 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.11 EGE04840.1 - 0.13 12.9 4.8 0.34 11.5 4.7 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Uso1_p115_C PF04871.13 EGE04840.1 - 0.47 10.8 7.4 0.59 10.5 4.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SATase_N PF06426.14 EGE04840.1 - 0.68 10.3 5.2 1.4 9.4 2.6 2.4 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal CENP-H PF05837.12 EGE04840.1 - 3.2 8.2 8.1 3.1 8.2 5.8 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 EGE04840.1 - 4 8.0 10.9 14 6.2 10.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ATP-synt_10 PF05176.14 EGE04841.1 - 5e-76 255.3 0.0 6.7e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_pol_B_palm PF14792.6 EGE04842.1 - 3.1e-33 114.4 0.0 6.1e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EGE04842.1 - 1.2e-22 79.8 0.0 2.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGE04842.1 - 1.4e-19 69.6 0.6 5.2e-19 67.8 0.3 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGE04842.1 - 5e-17 62.0 1.0 1.2e-16 60.9 1.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EGE04842.1 - 0.0092 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 EGE04842.1 - 0.052 14.2 0.1 19 5.9 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain Zn_clus PF00172.18 EGE04843.1 - 0.0053 16.8 9.3 0.013 15.6 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACOX PF01756.19 EGE04844.1 - 0.042 13.4 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA oxidase CPL PF08144.11 EGE04845.1 - 5.8e-34 117.5 0.0 3e-29 102.2 0.0 3.8 4 0 0 4 4 4 2 CPL (NUC119) domain DUF2457 PF10446.9 EGE04845.1 - 0.062 12.4 20.5 0.098 11.8 20.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LAP1C PF05609.12 EGE04845.1 - 0.31 10.1 14.1 0.49 9.4 14.1 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 EGE04845.1 - 0.8 7.8 22.7 1.2 7.2 22.7 1.2 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 EGE04845.1 - 2 8.8 14.0 7 7.1 14.0 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 EGE04845.1 - 4.4 5.5 18.9 7.5 4.7 18.9 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EGE04845.1 - 6.5 6.0 20.6 12 5.1 20.6 1.3 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 EGE04845.1 - 8.4 4.0 8.1 13 3.4 8.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2722 PF10846.8 EGE04845.1 - 8.9 5.1 16.2 13 4.6 16.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RXT2_N PF08595.11 EGE04845.1 - 8.9 6.3 12.8 26 4.8 12.8 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal A_amylase_inhib PF01356.19 EGE04847.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase inhibitor Rad51 PF08423.11 EGE04848.1 - 2e-128 427.0 0.0 2.5e-128 426.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EGE04848.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EGE04848.1 - 5.5e-08 32.6 0.0 7.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EGE04848.1 - 2.5e-05 24.8 1.1 6.2e-05 23.5 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EGE04848.1 - 0.00012 21.6 0.7 0.00054 19.4 0.7 2.0 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGE04848.1 - 0.0085 15.5 0.1 0.04 13.2 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HHH PF00633.23 EGE04848.1 - 0.021 14.7 0.4 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif ssDNA_TraI_N PF18272.1 EGE04848.1 - 0.043 13.8 0.7 0.21 11.6 0.1 2.3 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EGE04848.1 - 0.091 11.9 0.2 0.33 10.0 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 EGE04849.1 - 3.5e-133 445.1 7.1 4.9e-133 444.6 7.1 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_12 PF13424.6 EGE04849.1 - 0.17 12.2 0.4 1 9.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EGE04850.1 - 1.8e-30 106.1 17.4 2.2e-30 105.8 17.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04850.1 - 9.4e-08 31.3 6.9 1.4e-07 30.8 6.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGE04850.1 - 3e-06 25.9 2.5 4.1e-06 25.5 2.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3808 PF10300.9 EGE04851.1 - 2.2e-145 485.1 0.0 2.6e-145 484.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CIDR1_gamma PF18562.1 EGE04851.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Cysteine-Rich Interdomain Region 1 gamma DSS1_SEM1 PF05160.13 EGE04852.1 - 2.1e-21 75.7 13.8 2.7e-21 75.4 13.8 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EGE04852.1 - 0.11 12.4 2.6 0.12 12.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PGK PF00162.19 EGE04853.1 - 6.9e-149 495.9 0.3 7.8e-149 495.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EGE04853.1 - 0.0012 18.9 0.6 0.035 14.1 0.0 3.0 3 0 0 3 3 3 1 PA domain zf-C2H2 PF00096.26 EGE04854.1 - 1e-08 35.1 6.0 1.2e-05 25.5 0.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE04854.1 - 2.3e-08 34.1 8.4 7.6e-07 29.3 0.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EGE04854.1 - 4e-07 29.9 0.9 0.017 15.1 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGE04854.1 - 2.9e-05 24.5 6.8 0.002 18.8 0.4 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 EGE04854.1 - 0.00014 22.4 10.1 0.083 13.5 0.1 3.7 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EGE04854.1 - 0.046 13.5 1.1 0.092 12.5 0.1 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EGE04854.1 - 0.14 12.0 3.8 0.32 10.8 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 EGE04854.1 - 0.19 12.1 3.1 2.7 8.4 0.2 3.4 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EGE04854.1 - 0.23 11.8 3.5 1.4 9.2 0.5 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zap1_zf2 PF18217.1 EGE04854.1 - 0.57 10.2 6.9 3.1 7.9 0.7 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 zf_ZIC PF18366.1 EGE04854.1 - 0.6 10.3 3.4 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain SNF2_N PF00176.23 EGE04855.1 - 3.7e-56 190.3 0.1 1.1e-55 188.7 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.24 EGE04855.1 - 1.2e-24 85.9 0.4 1.6e-15 56.7 0.1 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EGE04855.1 - 2.4e-21 76.0 0.0 2.2e-20 72.9 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EGE04855.1 - 6.5e-18 65.1 0.0 2.2e-17 63.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 EGE04855.1 - 1.9e-06 28.2 6.9 4.6e-06 26.9 2.1 4.2 4 1 1 5 5 4 2 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 EGE04855.1 - 3.1e-06 26.6 0.0 1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGE04855.1 - 1.3e-05 25.3 0.2 0.00017 21.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 EGE04855.1 - 0.023 14.9 0.2 0.23 11.6 0.0 2.8 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain AAA_22 PF13401.6 EGE04855.1 - 0.059 13.6 0.0 0.28 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain SLIDE PF09111.10 EGE04855.1 - 0.06 13.4 0.0 0.63 10.1 0.0 2.8 1 1 1 2 2 2 0 SLIDE CDH1_2_SANT_HL1 PF18375.1 EGE04855.1 - 0.093 13.4 1.3 0.63 10.7 1.1 2.6 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 DUF2514 PF10721.9 EGE04855.1 - 0.36 10.8 4.1 1.9 8.5 4.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ABC_tran PF00005.27 EGE04856.1 - 3.7e-34 118.2 0.0 1.7e-15 57.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGE04856.1 - 3.3e-11 43.1 2.3 0.0029 17.1 0.0 3.9 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGE04856.1 - 1e-09 38.7 4.6 0.3 10.8 1.9 4.6 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 EGE04856.1 - 6e-07 29.2 1.6 6e-07 29.2 1.6 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Rad17 PF03215.15 EGE04856.1 - 1.7e-06 28.1 0.0 0.045 13.7 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA PF00004.29 EGE04856.1 - 1.8e-05 25.1 0.1 0.02 15.3 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EGE04856.1 - 2.8e-05 24.0 0.4 0.22 11.2 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGE04856.1 - 4.4e-05 23.8 0.0 0.0091 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.27 EGE04856.1 - 8.2e-05 22.3 2.5 8.2e-05 22.3 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 EGE04856.1 - 0.00013 22.4 0.0 0.036 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGE04856.1 - 0.00035 20.2 1.1 0.0035 16.9 0.2 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGE04856.1 - 0.00044 20.6 0.0 0.25 11.8 0.0 2.8 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 EGE04856.1 - 0.00053 19.9 0.2 0.93 9.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EGE04856.1 - 0.0011 19.5 0.1 2 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGE04856.1 - 0.0012 18.6 0.4 0.94 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_21 PF14697.6 EGE04856.1 - 0.0017 18.4 8.4 0.0034 17.5 8.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 EGE04856.1 - 0.0018 18.0 2.1 0.11 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGE04856.1 - 0.0027 17.3 2.9 0.062 12.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 EGE04856.1 - 0.0053 16.7 0.1 0.085 12.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGE04856.1 - 0.0058 15.9 1.6 1.5 7.9 0.0 3.4 3 1 1 4 4 4 1 NB-ARC domain NACHT PF05729.12 EGE04856.1 - 0.006 16.5 2.1 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Thymidylate_kin PF02223.17 EGE04856.1 - 0.0083 15.8 0.2 4.7 6.9 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase Fer4_6 PF12837.7 EGE04856.1 - 0.0088 16.1 2.2 0.0088 16.1 2.2 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 EGE04856.1 - 0.011 15.8 0.1 2 8.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGE04856.1 - 0.015 15.0 0.4 0.64 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 EGE04856.1 - 0.026 14.7 1.6 0.026 14.7 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_5 PF07728.14 EGE04856.1 - 0.027 14.5 0.1 1.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGE04856.1 - 0.028 14.9 2.8 0.59 10.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGE04856.1 - 0.028 14.7 0.1 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 EGE04856.1 - 0.03 14.5 8.8 0.067 13.4 8.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain TniB PF05621.11 EGE04856.1 - 0.06 12.8 0.1 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_13 PF13166.6 EGE04856.1 - 0.062 11.9 1.0 0.071 11.7 0.0 1.5 2 0 0 2 2 1 0 AAA domain VirE PF05272.11 EGE04856.1 - 0.067 12.9 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 EGE04856.1 - 0.075 14.0 5.5 0.084 13.8 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DnaB_C PF03796.15 EGE04856.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Fer4_17 PF13534.6 EGE04856.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 EGE04856.1 - 0.19 11.1 0.1 0.41 10.0 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 EGE04856.1 - 0.27 11.0 2.3 0.29 10.9 0.1 2.2 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_7 PF12838.7 EGE04856.1 - 0.3 11.7 9.1 1.2 9.8 9.3 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 EGE04856.1 - 0.42 10.5 3.2 4.6 7.1 0.1 2.8 3 0 0 3 3 2 0 NTPase Fer4_2 PF12797.7 EGE04856.1 - 1.7 8.9 6.8 0.29 11.3 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 EGE04856.1 - 4.4 7.8 10.3 1.3 9.6 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.19 EGE04857.1 - 9.6e-59 195.4 15.2 7.3e-15 54.9 0.0 7.1 6 1 0 6 6 6 5 FF domain WW PF00397.26 EGE04857.1 - 1.6e-17 63.3 13.5 3.1e-09 36.7 1.2 2.6 2 0 0 2 2 2 2 WW domain HycH PF07450.11 EGE04857.1 - 0.092 13.1 0.6 0.36 11.2 0.6 2.1 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH EMP24_GP25L PF01105.24 EGE04857.1 - 0.15 12.0 1.1 0.38 10.7 1.1 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Glyco_hyd_101C PF17451.2 EGE04857.1 - 0.37 11.1 7.1 13 6.1 0.3 3.0 2 1 0 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain SesA PF17107.5 EGE04857.1 - 9.7 6.4 8.9 0.68 10.1 0.6 3.2 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Trs65 PF12735.7 EGE04858.1 - 2.4e-85 286.7 0.0 7.7e-85 285.1 0.0 1.7 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 EGE04859.1 - 7.8e-19 67.7 0.1 1.8e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EGE04860.1 - 2.4e-29 102.4 31.9 4e-28 98.4 29.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGE04862.1 - 2.5e-62 211.1 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4485 PF14846.6 EGE04862.1 - 0.38 10.8 1.4 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Amidase PF01425.21 EGE04863.1 - 4.8e-102 342.2 0.0 6.9e-102 341.7 0.0 1.2 1 0 0 1 1 1 1 Amidase Arm PF00514.23 EGE04864.1 - 9.1e-95 308.2 11.0 2.3e-14 52.8 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EGE04864.1 - 1.2e-27 96.1 1.4 4.7e-27 94.3 0.6 2.2 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 EGE04864.1 - 4.7e-22 77.3 4.3 6e-22 77.0 2.9 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 EGE04864.1 - 2.2e-20 72.9 0.1 4.2e-09 36.7 0.0 5.0 2 2 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EGE04864.1 - 8.3e-20 70.9 6.9 1.7e-08 34.7 0.1 6.5 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.22 EGE04864.1 - 1.9e-18 65.0 0.2 1.8e-05 24.6 0.0 6.8 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 EGE04864.1 - 7e-08 32.2 0.0 0.0056 16.2 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 EGE04864.1 - 2.6e-05 24.3 0.0 1.2 9.3 0.0 4.6 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 EGE04864.1 - 3.7e-05 22.5 0.0 0.009 14.6 0.0 2.9 1 1 1 3 3 3 1 Adaptin N terminal region HEAT_PBS PF03130.16 EGE04864.1 - 0.00068 20.1 1.5 0.96 10.3 0.1 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EGE04864.1 - 0.0017 18.4 0.0 6 6.9 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CTNNBL PF08216.11 EGE04864.1 - 0.0039 17.3 0.0 35 4.6 0.0 4.5 4 0 0 4 4 4 0 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 EGE04864.1 - 0.022 14.8 0.1 14 5.8 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Gcn1_N PF12074.8 EGE04864.1 - 0.071 12.4 0.0 13 5.0 0.0 2.5 2 1 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RICTOR_V PF14668.6 EGE04864.1 - 0.08 13.2 4.6 2.8 8.2 0.2 4.4 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Mo25 PF08569.11 EGE04864.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Mo25-like NopRA1 PF16201.5 EGE04864.1 - 0.16 11.5 0.0 51 3.4 0.0 3.7 2 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 NUSAP PF16006.5 EGE04864.1 - 0.4 10.4 7.8 0.56 9.9 7.8 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein POT1PC PF16686.5 EGE04865.1 - 1.1e-47 161.8 1.6 1.3e-46 158.3 1.0 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EGE04865.1 - 3.6e-10 39.8 0.0 1.2e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Gemini_AL1 PF00799.20 EGE04865.1 - 0.051 13.9 1.1 0.36 11.2 1.1 2.2 1 1 0 1 1 1 0 Geminivirus Rep catalytic domain Peptidase_S49_N PF08496.10 EGE04865.1 - 6.8 6.7 6.7 6 6.9 4.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-CCCH_4 PF18044.1 EGE04866.1 - 1.1 9.2 10.3 0.36 10.7 2.1 2.8 2 0 0 2 2 2 0 CCCH-type zinc finger TRAP_alpha PF03896.16 EGE04867.1 - 5.4e-13 48.8 0.0 1.7e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit HA2 PF04408.23 EGE04868.1 - 9.8e-16 58.0 0.4 2.3e-15 56.8 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGE04868.1 - 5.7e-15 55.4 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGE04868.1 - 8.7e-14 51.8 0.0 1.9e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 EGE04868.1 - 3.8e-11 43.3 0.1 8.1e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 EGE04868.1 - 6.4e-10 39.1 0.1 1.2e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE04868.1 - 0.0049 17.1 0.8 0.03 14.6 0.8 2.3 1 1 0 1 1 1 1 AAA domain CoA_trans PF01144.23 EGE04868.1 - 0.0058 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Coenzyme A transferase DND1_DSRM PF14709.7 EGE04868.1 - 0.0073 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SSE PF00437.20 EGE04868.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UBA PF00627.31 EGE04868.1 - 0.014 15.3 0.0 0.12 12.3 0.0 2.6 3 0 0 3 3 3 0 UBA/TS-N domain AAA_29 PF13555.6 EGE04868.1 - 0.021 14.5 0.0 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 EGE04868.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 KaiC dsRBD2 PF17842.1 EGE04868.1 - 0.027 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 EGE04868.1 - 0.066 13.7 0.9 0.16 12.5 0.0 2.0 3 0 0 3 3 1 0 AAA domain BTRD1 PF17660.1 EGE04868.1 - 0.15 11.9 0.1 0.9 9.4 0.2 2.3 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 AAA_16 PF13191.6 EGE04868.1 - 0.16 12.4 0.4 1.6 9.1 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain NICE-3 PF07406.11 EGE04870.1 - 0.00047 20.2 0.1 0.001 19.1 0.0 1.6 2 0 0 2 2 2 1 NICE-3 protein DUF4129 PF13559.6 EGE04870.1 - 0.0091 16.2 0.0 0.046 14.0 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4129) DUF4393 PF14337.6 EGE04870.1 - 0.022 14.6 0.1 5.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4393) DUF3810 PF12725.7 EGE04870.1 - 0.54 9.6 1.9 0.81 9.0 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) GCFC PF07842.12 EGE04871.1 - 1.7e-86 290.3 7.6 2.9e-86 289.5 7.6 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EGE04871.1 - 5.1e-16 58.3 0.5 9.7e-16 57.4 0.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGE04871.1 - 3e-07 30.4 0.2 1e-06 28.7 0.2 2.0 1 0 0 1 1 1 1 G-patch domain ATP-synt_E PF05680.12 EGE04871.1 - 8.7 6.8 6.5 2.6 8.4 1.9 2.5 2 0 0 2 2 2 0 ATP synthase E chain Sod_Fe_C PF02777.18 EGE04872.1 - 4.4e-37 126.4 0.1 7.7e-37 125.6 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGE04872.1 - 4.8e-30 103.9 0.9 7.7e-30 103.2 0.9 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cnn_1N PF07989.11 EGE04873.1 - 4.4e-06 26.8 15.5 1.6e-05 25.0 15.5 1.9 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF724 PF05266.14 EGE04873.1 - 0.011 15.5 6.7 0.021 14.7 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc7 PF08317.11 EGE04873.1 - 0.26 10.1 16.2 0.39 9.5 16.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 EGE04873.1 - 0.51 11.0 10.4 1.5 9.5 10.4 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Prominin PF05478.11 EGE04873.1 - 0.65 7.9 5.7 0.93 7.4 5.7 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 EGE04873.1 - 0.78 9.8 17.6 1.4 9.0 17.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 EGE04873.1 - 1.5 9.3 13.5 3 8.3 13.5 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EGE04873.1 - 9.6 3.6 21.6 14 3.0 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sld5 PF05916.11 EGE04874.1 - 2.6e-20 72.9 0.0 3.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DDE_Tnp_1_2 PF13586.6 EGE04875.1 - 0.051 13.9 0.3 7.5 7.0 1.1 2.9 2 0 0 2 2 2 0 Transposase DDE domain DNA_pol_phi PF04931.13 EGE04875.1 - 0.26 9.4 6.4 0.37 8.8 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.19 EGE04875.1 - 1.5 9.4 27.5 0.28 11.8 4.4 3.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 EGE04875.1 - 1.6 9.2 13.9 0.33 11.4 9.7 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRN3 PF05327.11 EGE04875.1 - 3.7 6.0 4.1 6.4 5.2 4.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EGE04875.1 - 9.9 5.8 9.4 1.2 8.8 3.3 2.6 2 0 0 2 2 2 0 FAM176 family ABC_tran_Xtn PF12848.7 EGE04876.1 - 0.021 14.9 0.3 0.069 13.2 0.3 1.9 1 0 0 1 1 1 0 ABC transporter PH_10 PF15411.6 EGE04879.1 - 6.9e-39 132.9 0.0 1.5e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EGE04879.1 - 2.4e-34 117.4 0.0 8e-34 115.8 0.0 1.8 2 0 0 2 2 2 1 CDC24 Calponin PB1 PF00564.24 EGE04879.1 - 5.3e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 EGE04880.1 - 4.4e-28 96.9 6.6 9.6e-05 23.1 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04880.1 - 0.00018 21.7 0.8 16 5.9 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGE04880.1 - 0.0014 18.6 0.0 3.1 7.9 0.0 3.5 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGE04880.1 - 0.1 11.9 0.0 9 5.5 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 EGE04880.1 - 0.19 10.4 0.2 13 4.3 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 SOCS PF12610.8 EGE04881.1 - 1.1 9.7 10.0 3.7 8.0 0.0 3.5 3 0 0 3 3 3 0 Suppressor of cytokine signalling Uds1 PF15456.6 EGE04882.1 - 1.6e-38 131.8 1.4 1.6e-38 131.8 1.4 6.5 4 2 1 6 6 6 1 Up-regulated During Septation TMF_DNA_bd PF12329.8 EGE04882.1 - 0.00041 20.3 10.3 0.00041 20.3 10.3 9.3 10 1 1 11 11 11 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EGE04882.1 - 0.002 18.2 19.2 0.0073 16.4 17.7 8.0 6 1 2 8 8 8 3 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 EGE04882.1 - 0.0029 16.8 22.9 0.0029 16.8 22.9 4.8 3 1 1 4 4 4 3 Myosin-like coiled-coil protein DUF4472 PF14739.6 EGE04882.1 - 0.012 16.3 10.7 0.012 16.3 10.7 6.1 3 2 3 7 7 7 0 Domain of unknown function (DUF4472) ApoO PF09769.9 EGE04882.1 - 0.89 9.5 8.9 6.2 6.8 1.5 4.5 3 1 2 5 5 5 0 Apolipoprotein O Sin3_corepress PF08295.12 EGE04882.1 - 2.8 8.1 10.1 0.13 12.3 0.6 3.6 2 1 1 3 3 3 0 Sin3 family co-repressor Vac_Fusion PF02346.16 EGE04882.1 - 5.5 6.7 9.1 18 5.0 1.1 3.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF4407 PF14362.6 EGE04882.1 - 6.8 6.0 58.4 0.42 9.9 16.5 4.6 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 EGE04883.1 - 1.5e-23 83.3 32.4 2.2e-23 82.8 32.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.16 EGE04884.1 - 1.6e-26 92.3 6.6 1.6e-26 92.3 6.6 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 EGE04884.1 - 0.0042 17.1 0.6 0.0056 16.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) ORC_WH_C PF18137.1 EGE04884.1 - 0.052 13.6 1.4 0.082 13.0 1.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal KIND PF16474.5 EGE04884.1 - 0.17 11.8 4.6 0.22 11.4 4.6 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Ribosomal_60s PF00428.19 EGE04884.1 - 0.19 12.4 14.2 0.4 11.3 14.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Radial_spoke PF04712.12 EGE04884.1 - 2.4 7.0 10.1 2.6 6.9 10.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein TRAP_alpha PF03896.16 EGE04884.1 - 3.3 6.8 5.6 3.4 6.8 5.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GOLD_2 PF13897.6 EGE04884.1 - 4.9 7.6 6.0 8.7 6.8 6.0 1.5 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Vps36_ESCRT-II PF11605.8 EGE04885.1 - 0.00037 20.6 0.0 0.11 12.7 0.0 2.3 1 1 1 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 DUF3439 PF11921.8 EGE04885.1 - 0.12 12.3 6.2 0.15 12.0 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EGE04885.1 - 0.33 8.9 3.4 0.4 8.6 3.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGE04885.1 - 2.1 8.3 14.0 3.5 7.6 14.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGE04885.1 - 3.1 5.9 10.2 4.5 5.4 10.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM70 PF14967.6 EGE04886.1 - 0.91 8.9 3.3 1.1 8.6 3.3 1.1 1 0 0 1 1 1 0 FAM70 protein DUF4639 PF15479.6 EGE04887.1 - 0.068 12.1 0.1 0.08 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Acyltransferase PF01553.21 EGE04889.1 - 1.1e-09 38.0 0.0 0.00041 20.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.19 EGE04890.1 - 1.8e-71 240.2 0.4 1.7e-69 233.8 0.4 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 EGE04891.1 - 1.5e-95 320.3 0.0 3.1e-95 319.3 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGE04891.1 - 6e-23 81.5 0.6 1e-22 80.8 0.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGE04891.1 - 3e-06 27.4 0.1 5.9e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EGE04891.1 - 0.0013 18.6 0.7 0.025 14.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EGE04891.1 - 0.061 13.8 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 EGE04892.1 - 2.9e-23 83.4 0.0 6.1e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGE04892.1 - 2.6e-15 56.5 0.1 4.1e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE04892.1 - 0.026 14.4 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PGM_PMM_II PF02879.16 EGE04892.1 - 0.14 12.8 0.0 0.53 10.9 0.0 2.0 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Glyco_hydro_15 PF00723.21 EGE04893.1 - 3.5e-93 312.8 0.1 4.3e-93 312.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EGE04893.1 - 6.1e-28 96.6 0.0 1.5e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Aha1_N PF09229.11 EGE04894.1 - 1.3e-40 138.8 0.6 2.4e-40 137.9 0.6 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGE04894.1 - 4e-19 69.1 0.1 6.7e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Mucin PF01456.17 EGE04894.1 - 3 7.8 16.2 5.2 7.1 16.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.20 EGE04897.1 - 7.1e-69 231.1 0.1 9.1e-69 230.7 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain OAD_gamma PF04277.13 EGE04898.1 - 0.0067 17.0 0.6 0.02 15.5 0.6 1.9 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain SPX PF03105.19 EGE04898.1 - 0.45 10.4 3.4 0.49 10.3 3.4 1.1 1 0 0 1 1 1 0 SPX domain Orf78 PF06024.12 EGE04898.1 - 0.52 10.6 3.6 0.23 11.8 1.3 1.5 2 0 0 2 2 2 0 Orf78 (ac78) Shisa PF13908.6 EGE04898.1 - 1.5 9.0 5.1 0.62 10.3 1.6 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Fungal_trans_2 PF11951.8 EGE04899.1 - 3.4e-32 111.7 0.3 2.1e-31 109.1 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE04899.1 - 2.2e-07 30.9 11.1 3.5e-07 30.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 EGE04900.1 - 1.4e-37 129.0 12.2 7.8e-30 103.7 0.0 3.7 3 1 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE04900.1 - 2e-21 76.5 6.3 2e-21 76.5 6.3 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGE04900.1 - 4.8e-20 72.8 0.0 3.5e-19 69.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE04900.1 - 9.1e-17 60.9 0.0 2.1e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGE04900.1 - 5.9e-15 54.7 0.0 1.5e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGE04900.1 - 0.0016 18.2 0.9 0.017 14.8 1.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Na_Pi_cotrans PF02690.15 EGE04900.1 - 0.99 9.5 8.5 0.034 14.2 1.7 2.1 2 0 0 2 2 2 0 Na+/Pi-cotransporter HlyIII PF03006.20 EGE04901.1 - 1.2e-32 113.5 14.2 1.5e-32 113.1 14.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF308 PF03729.13 EGE04901.1 - 0.094 13.1 0.8 0.094 13.1 0.8 2.3 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF1129 PF06570.11 EGE04901.1 - 2.9 7.3 4.3 24 4.3 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Sugar_tr PF00083.24 EGE04902.1 - 1.7e-83 281.0 22.1 2.1e-83 280.7 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE04902.1 - 4.7e-26 91.6 34.0 7.9e-18 64.5 10.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF5090 PF17009.5 EGE04902.1 - 0.14 12.1 3.2 0.43 10.5 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) V_ATPase_I PF01496.19 EGE04903.1 - 0 1073.8 0.2 0 1073.6 0.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 EGE04903.1 - 0.0016 18.5 0.2 0.0048 16.9 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.13 EGE04903.1 - 0.0096 15.9 4.6 0.33 10.9 0.4 2.4 2 0 0 2 2 2 2 Chemotaxis phosphatase, CheZ DUF4988 PF16378.5 EGE04903.1 - 0.12 12.0 0.2 0.29 10.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1664 PF07889.12 EGE04903.1 - 0.21 11.7 3.6 10 6.1 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 EGE04903.1 - 0.22 11.3 5.1 11 5.8 0.0 3.3 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF16 PF01519.16 EGE04903.1 - 0.25 11.8 2.5 8.5 6.9 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function DUF16 Tektin PF03148.14 EGE04903.1 - 0.27 9.9 7.4 0.31 9.7 2.2 2.2 2 0 0 2 2 2 0 Tektin family Filament PF00038.21 EGE04903.1 - 0.34 10.5 9.3 2.7 7.5 0.1 2.4 2 1 0 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 EGE04903.1 - 0.65 10.3 4.3 3.3 8.1 1.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3552 PF12072.8 EGE04903.1 - 0.82 9.0 5.0 11 5.3 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Fmp27_WPPW PF10359.9 EGE04903.1 - 1.7 7.4 4.7 0.69 8.7 1.3 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 EGE04903.1 - 2 8.2 3.9 2 8.2 0.3 2.8 3 0 0 3 3 3 0 Septum formation initiator FapA PF03961.13 EGE04903.1 - 2.7 6.5 5.6 0.51 8.9 0.6 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Nup54 PF13874.6 EGE04903.1 - 2.9 8.0 5.2 4.1 7.5 1.3 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 HMMR_N PF15905.5 EGE04903.1 - 4 6.8 6.2 2.1 7.7 1.8 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MOSC PF03473.17 EGE04904.1 - 4e-05 23.6 0.1 6.9e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 MOSC domain BLM10_mid PF16507.5 EGE04905.1 - 1.6e-168 561.7 0.0 3.3e-168 560.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGE04905.1 - 2.2e-19 69.1 0.0 1.1e-18 66.9 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EGE04905.1 - 5.7e-17 61.8 0.1 1.9e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT_2 PF13646.6 EGE04905.1 - 0.018 15.4 0.1 15 6.1 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 EGE04905.1 - 0.03 14.6 0.2 3.7 8.1 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Mannosyl_trans2 PF04188.13 EGE04906.1 - 3.6e-53 181.5 11.4 5.7e-53 180.8 11.4 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Pro_CA PF00484.19 EGE04908.1 - 1.4e-32 113.2 0.1 1.9e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.8 EGE04910.1 - 2.4e-47 162.0 0.7 4.2e-33 115.3 0.2 3.3 2 1 2 4 4 4 2 Velvet factor MOZ_SAS PF01853.18 EGE04912.1 - 1.1e-34 119.7 0.0 1.9e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD_4 PF16866.5 EGE04912.1 - 1.8e-08 34.4 12.3 5.3e-08 32.8 12.3 1.9 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EGE04912.1 - 0.0034 17.2 12.0 0.0073 16.2 12.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGE04912.1 - 0.032 13.8 6.8 0.02 14.5 4.5 1.9 2 0 0 2 2 2 0 PHD-finger MWFE PF15879.5 EGE04913.1 - 1.1e-25 89.5 0.1 1.4e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Acetyltransf_2 PF00797.17 EGE04914.1 - 2.8e-40 138.6 0.0 3.9e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase RraA-like PF03737.15 EGE04915.1 - 1.5e-31 109.6 0.1 1.9e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA NTP_transf_3 PF12804.7 EGE04915.1 - 0.065 13.6 0.1 0.37 11.1 0.0 1.9 1 1 1 2 2 2 0 MobA-like NTP transferase domain Thiolase_N PF00108.23 EGE04916.1 - 1.9e-73 247.0 2.8 3.3e-73 246.3 2.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE04916.1 - 5.6e-44 148.7 0.2 1.1e-43 147.8 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGE04916.1 - 0.027 14.0 0.5 0.14 11.7 0.3 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain GFO_IDH_MocA PF01408.22 EGE04918.1 - 5.8e-20 72.3 0.3 1.3e-19 71.2 0.1 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold APH PF01636.23 EGE04919.1 - 1.3e-08 35.1 0.1 4.8e-08 33.2 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE04919.1 - 5.8e-06 26.0 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGE04919.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_GBD PF06371.13 EGE04920.1 - 5.2e-19 68.5 5.6 6e-17 61.8 5.6 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Snf7 PF03357.21 EGE04921.1 - 7.9e-44 149.3 12.7 9.7e-44 149.0 12.7 1.0 1 0 0 1 1 1 1 Snf7 DUF3584 PF12128.8 EGE04921.1 - 0.00032 18.4 4.8 0.00044 17.9 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 EGE04921.1 - 0.00077 18.6 1.6 0.00095 18.3 1.6 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 EGE04921.1 - 0.0014 18.9 2.1 0.47 10.8 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EGE04921.1 - 0.011 16.1 5.5 0.41 11.1 2.0 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 EGE04921.1 - 0.012 15.3 7.3 0.013 15.3 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HsbA PF12296.8 EGE04921.1 - 0.069 13.6 0.3 0.38 11.2 0.3 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Alpha-2-MRAP_C PF06401.11 EGE04921.1 - 0.095 12.7 2.3 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF948 PF06103.11 EGE04921.1 - 0.13 12.5 0.6 0.66 10.3 0.6 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 EGE04921.1 - 0.26 11.7 5.0 33 5.0 0.8 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EGE04921.1 - 0.3 11.4 6.4 0.57 10.5 0.1 3.2 2 2 0 2 2 2 0 ABC transporter C-terminal domain Vps51 PF08700.11 EGE04921.1 - 1.6 8.9 6.3 2.7 8.1 0.6 3.1 2 1 1 3 3 3 0 Vps51/Vps67 DASH_Dam1 PF08653.10 EGE04921.1 - 1.9 8.4 3.6 22 5.0 0.3 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4094 PF13334.6 EGE04921.1 - 2.9 8.4 5.0 12 6.4 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 EGE04921.1 - 5.6 7.7 10.4 11 6.7 1.7 3.6 1 1 2 3 3 3 0 SlyX SAPS PF04499.15 EGE04922.1 - 1.8e-179 597.6 0.2 1.8e-179 597.6 0.2 2.1 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein SET PF00856.28 EGE04923.1 - 0.0022 18.4 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 SET domain Complex1_51K PF01512.17 EGE04924.1 - 1.3e-38 132.2 0.0 2.4e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGE04924.1 - 2.8e-29 101.0 2.0 3.7e-29 100.6 0.3 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGE04924.1 - 9.5e-09 35.0 0.0 2.5e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Nup96 PF12110.8 EGE04925.1 - 1.1e-76 257.8 0.0 1.6e-76 257.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGE04925.1 - 4.5e-52 176.1 0.0 8.4e-52 175.3 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EGE04925.1 - 3.3e-13 50.3 81.0 7.8e-11 42.7 43.5 10.2 5 3 4 9 9 9 2 Nucleoporin FG repeat region zf-C3Hc3H PF13891.6 EGE04926.1 - 0.048 14.0 2.5 0.13 12.7 2.5 1.8 1 1 0 1 1 1 0 Potential DNA-binding domain AMP-binding PF00501.28 EGE04927.1 - 1.2e-63 215.2 0.1 9.1e-61 205.7 0.4 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EGE04927.1 - 2e-27 96.0 2.2 1.2e-25 90.2 1.7 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGE04927.1 - 1.8e-15 56.5 0.1 5.2e-15 55.1 0.1 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GET2 PF08690.10 EGE04928.1 - 3.5e-09 36.8 0.0 5.8e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 HTH_24 PF13412.6 EGE04928.1 - 0.053 13.1 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding C2 PF00168.30 EGE04929.1 - 5.5e-29 100.5 0.0 1e-16 61.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain IMS PF00817.20 EGE04932.1 - 4.6e-40 137.1 0.0 7.4e-40 136.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EGE04932.1 - 1.5e-16 61.2 0.0 1e-15 58.5 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Reprolysin_5 PF13688.6 EGE04934.1 - 2.8e-58 197.3 6.7 2.8e-58 197.3 6.7 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EGE04934.1 - 3.3e-46 157.7 1.6 7.4e-46 156.5 1.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGE04934.1 - 6.7e-43 146.7 1.6 1.2e-42 145.8 1.6 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EGE04934.1 - 2e-14 54.1 34.9 2e-14 54.1 34.9 4.2 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EGE04934.1 - 3e-11 43.9 0.0 7.8e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EGE04934.1 - 1.8e-06 28.4 1.5 1.8e-06 28.4 1.5 5.2 2 1 4 6 6 6 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EGE04934.1 - 0.013 15.7 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide EF-hand_7 PF13499.6 EGE04935.1 - 3.1e-16 59.6 0.6 5.2e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGE04935.1 - 1.3e-14 52.5 1.5 1.8e-05 23.9 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGE04935.1 - 1.8e-13 49.2 3.4 1.8e-05 24.3 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGE04935.1 - 1.9e-11 43.6 1.3 1.3e-08 34.6 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair DUF3572 PF12096.8 EGE04935.1 - 0.024 14.8 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_5 PF13202.6 EGE04935.1 - 0.034 13.6 4.2 1.4 8.5 0.1 2.7 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 EGE04935.1 - 0.053 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 EGE04935.1 - 0.16 12.1 0.3 0.54 10.4 0.0 2.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand MgsA_C PF12002.8 EGE04936.1 - 2.1e-58 197.0 0.1 3.5e-58 196.2 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGE04936.1 - 3.1e-24 85.1 0.6 6.6e-24 84.1 0.6 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGE04936.1 - 5.3e-14 52.8 0.0 1.2e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGE04936.1 - 2.2e-11 43.7 0.0 4.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGE04936.1 - 9.7e-06 25.1 0.2 0.044 13.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE04936.1 - 4.1e-05 23.6 0.0 0.0013 18.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGE04936.1 - 7e-05 22.6 0.0 0.0037 17.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGE04936.1 - 0.0001 22.7 0.3 0.038 14.4 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 EGE04936.1 - 0.00034 20.5 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGE04936.1 - 0.00093 19.5 0.1 0.0039 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGE04936.1 - 0.0015 17.8 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGE04936.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGE04936.1 - 0.0059 16.6 0.1 0.52 10.3 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EGE04936.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGE04936.1 - 0.021 14.5 0.2 0.081 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGE04936.1 - 0.028 13.6 0.1 0.054 12.7 0.1 1.3 1 1 0 1 1 1 0 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 EGE04936.1 - 0.036 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 EGE04936.1 - 0.037 13.2 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 EGE04936.1 - 0.063 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EGE04936.1 - 0.076 12.8 0.1 5.1 6.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EGE04936.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGE04936.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EGE04936.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EGE04936.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGE04936.1 - 0.15 12.0 0.0 3.5 7.5 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGE04936.1 - 0.15 12.4 0.2 0.53 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EGE04936.1 - 0.2 10.3 0.1 0.39 9.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EGE04937.1 - 3.2e-71 240.4 0.0 3.7e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGE04937.1 - 7.5e-05 22.2 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGE04937.1 - 0.00014 21.0 0.1 0.0016 17.5 0.1 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGE04937.1 - 0.00022 19.9 0.0 0.00048 18.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGE04937.1 - 0.0099 15.2 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family KH_1 PF00013.29 EGE04938.1 - 2e-47 158.9 8.0 1.5e-15 56.7 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGE04938.1 - 7.5e-13 48.1 2.3 0.00077 19.2 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EGE04938.1 - 4.9e-10 39.1 3.9 0.014 15.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EGE04938.1 - 0.0051 16.9 3.1 7.4 6.7 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain TFIIA PF03153.13 EGE04938.1 - 0.92 9.4 22.4 2.4 8.1 22.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGE04938.1 - 4.2 6.0 6.2 7.7 5.2 6.2 1.4 1 0 0 1 1 1 0 Presenilin Amidoligase_2 PF12224.8 EGE04939.1 - 0.00025 20.8 0.0 0.17 11.5 0.0 2.3 1 1 1 2 2 2 2 Putative amidoligase enzyme DUF3517 PF12030.8 EGE04939.1 - 0.019 13.9 0.0 0.052 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) DUF3665 PF12427.8 EGE04940.1 - 1.1e-05 25.0 0.3 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 Branched-chain amino acid aminotransferase HHH_3 PF12836.7 EGE04940.1 - 0.021 15.1 0.0 6.7 7.0 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif Ald_Xan_dh_C2 PF02738.18 EGE04942.1 - 1.3e-205 684.0 0.4 1.9e-205 683.5 0.4 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGE04942.1 - 5.6e-45 153.1 0.0 1.1e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGE04942.1 - 4.9e-34 116.6 0.0 1.9e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGE04942.1 - 3.9e-29 101.2 0.0 8.8e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EGE04942.1 - 6.5e-28 96.6 0.0 1.6e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EGE04942.1 - 5.4e-09 35.9 0.5 1.5e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain PDGF PF00341.17 EGE04942.1 - 0.19 12.0 0.4 0.55 10.6 0.4 1.7 1 0 0 1 1 1 0 PDGF/VEGF domain NAD_binding_4 PF07993.12 EGE04943.1 - 1.9e-72 243.5 0.0 2.8e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EGE04943.1 - 1.2e-61 208.6 0.0 2e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EGE04943.1 - 7.9e-11 41.9 0.0 2e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGE04943.1 - 1.4e-08 35.0 0.0 3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 EGE04943.1 - 1.6e-05 23.8 0.1 8.7e-05 21.4 0.1 1.9 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 EGE04943.1 - 8.1e-05 23.5 0.0 0.00032 21.6 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EGE04943.1 - 0.00012 21.2 0.0 0.00034 19.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGE04943.1 - 0.0016 18.4 0.0 0.046 13.6 0.0 2.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGE04943.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF769 PF05590.11 EGE04943.1 - 0.077 12.4 0.1 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) RmlD_sub_bind PF04321.17 EGE04943.1 - 0.082 12.0 0.0 0.38 9.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain PRK PF00485.18 EGE04944.1 - 0.00021 21.1 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EGE04944.1 - 0.00034 21.1 0.0 0.00049 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGE04944.1 - 0.0055 17.1 0.0 0.0091 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGE04944.1 - 0.02 15.4 0.0 0.05 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGE04944.1 - 0.055 13.7 0.2 0.13 12.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGE04944.1 - 0.13 12.6 0.1 0.61 10.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGE04944.1 - 0.14 11.9 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.23 EGE04945.1 - 1.1e-10 40.8 0.0 3.3e-07 29.3 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE04945.1 - 1.3e-08 35.2 0.0 8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HMG_box PF00505.19 EGE04946.1 - 5e-20 71.7 0.1 9.7e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGE04946.1 - 2.2e-05 25.0 0.0 4.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.19 EGE04947.1 - 5.3e-34 116.9 0.1 9.2e-30 103.2 0.1 2.6 1 1 1 2 2 2 2 Ribosomal protein S6e Pribosyltran_N PF13793.6 EGE04948.1 - 1.9e-47 160.0 0.3 6.2e-45 151.9 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGE04948.1 - 5.4e-44 150.4 1.0 4.4e-37 127.9 0.4 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGE04948.1 - 8.2e-19 67.7 0.5 9.3e-18 64.3 0.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGE04948.1 - 0.002 17.6 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 EGE04949.1 - 1e-121 406.4 11.9 6.4e-120 400.5 0.0 5.6 4 3 0 4 4 4 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EGE04949.1 - 3.4e-103 345.8 7.1 3.4e-103 345.8 7.1 4.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EGE04949.1 - 5.2e-76 256.1 0.0 5e-69 233.1 0.0 2.8 2 1 1 3 3 3 2 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EGE04949.1 - 1.7e-28 97.1 26.9 4.3e-10 38.7 3.2 4.5 4 0 0 4 4 4 3 Ubiquitin binding region UBA PF00627.31 EGE04949.1 - 0.00092 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain An_peroxidase PF03098.15 EGE04950.1 - 6.1e-37 127.4 0.0 1.9e-24 86.1 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EGE04950.1 - 1.7e-09 36.9 0.0 4.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Steroid_dh PF02544.16 EGE04952.1 - 3e-31 108.4 0.2 3.9e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EGE04952.1 - 2.6e-06 27.2 0.3 3.3e-06 26.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGE04952.1 - 6.6e-05 23.3 0.3 0.00014 22.2 0.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.12 EGE04953.1 - 4.6e-58 196.7 0.0 5.7e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.19 EGE04954.1 - 4.1e-16 58.9 0.7 7.3e-16 58.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.13 EGE04955.1 - 3.8e-166 552.6 0.1 4.5e-166 552.3 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGE04955.1 - 6.9e-21 74.2 0.1 3.3e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EGE04955.1 - 1.9e-11 44.5 0.3 2.6e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGE04955.1 - 9.7e-10 38.4 0.1 2.7e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE04955.1 - 9.6e-06 25.9 0.1 0.047 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGE04955.1 - 9.8e-05 22.7 0.2 0.066 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGE04955.1 - 0.00017 22.1 0.2 0.0034 17.8 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EGE04955.1 - 0.00036 20.8 0.2 0.001 19.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGE04955.1 - 0.00087 19.3 0.2 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGE04955.1 - 0.0015 18.3 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 EGE04955.1 - 0.0039 17.6 0.1 0.062 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGE04955.1 - 0.0047 16.2 0.2 0.013 14.8 0.2 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EGE04955.1 - 0.0071 15.9 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EGE04955.1 - 0.0079 15.6 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ATPase PF06745.13 EGE04955.1 - 0.014 14.8 0.6 0.12 11.7 0.0 2.4 3 0 0 3 3 3 0 KaiC Mg_chelatase PF01078.21 EGE04955.1 - 0.017 14.5 0.1 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGE04955.1 - 0.032 14.3 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TetR_C_30 PF17939.1 EGE04955.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IstB_IS21 PF01695.17 EGE04955.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGE04955.1 - 0.056 14.0 0.1 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGE04955.1 - 0.058 12.9 0.1 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EGE04955.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EGE04955.1 - 0.11 12.2 0.2 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain V-SNARE PF05008.15 EGE04956.1 - 4.6e-23 81.4 7.2 4.6e-23 81.4 7.2 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGE04956.1 - 3e-15 56.3 2.0 3e-15 56.3 2.0 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1542 PF07564.11 EGE04956.1 - 0.12 12.5 6.5 0.16 12.1 4.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) CDPS PF16715.5 EGE04956.1 - 0.16 11.6 2.0 0.17 11.5 1.6 1.3 1 1 0 1 1 1 0 Cyclodipeptide synthase DUF4355 PF14265.6 EGE04956.1 - 0.7 10.1 8.3 0.16 12.2 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Exonuc_VII_L PF02601.15 EGE04956.1 - 0.93 9.0 12.4 1.4 8.4 12.4 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit TBCA PF02970.16 EGE04956.1 - 1.1 9.6 8.2 0.57 10.6 2.6 2.7 2 1 0 2 2 2 0 Tubulin binding cofactor A zf-C4H2 PF10146.9 EGE04956.1 - 1.1 9.5 9.6 7.4 6.8 9.9 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DUF349 PF03993.12 EGE04956.1 - 2 8.8 11.1 3.3 8.1 0.3 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) FUSC PF04632.12 EGE04956.1 - 2 6.8 9.4 0.16 10.4 3.2 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 EGE04956.1 - 8.8 4.1 6.7 2.5 5.9 2.6 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2407_C PF13373.6 EGE04957.1 - 1.7e-42 145.0 0.1 2.5e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EGE04957.1 - 4.5e-35 120.3 0.0 6.8e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EGE04957.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD_2 PF13881.6 EGE04957.1 - 0.036 14.2 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.20 EGE04958.1 - 1.1e-20 73.9 0.0 4.9e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis 2OG-Fe_Oxy_2 PF10014.9 EGE04959.1 - 5.7e-46 156.7 0.1 7.9e-46 156.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase MFS_1 PF07690.16 EGE04960.1 - 5e-28 98.0 30.6 5.9e-28 97.8 30.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE04960.1 - 6.5e-15 54.9 8.1 7.9e-15 54.7 8.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGE04960.1 - 5.9e-06 25.8 5.3 8e-06 25.4 5.3 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF1741 PF08427.10 EGE04961.1 - 4.4e-45 154.2 0.0 7.5e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) CsgG PF03783.14 EGE04961.1 - 0.042 13.1 0.0 0.098 11.9 0.0 1.6 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG MRG PF05712.13 EGE04962.1 - 2.3e-44 151.1 0.0 3.2e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGE04962.1 - 7.8e-08 32.1 2.2 1.5e-07 31.2 2.2 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.10 EGE04963.1 - 3.5e-28 97.6 3.3 5.8e-28 96.8 3.3 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein APG6_N PF17675.1 EGE04963.1 - 0.024 15.2 1.9 0.11 13.1 1.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 EGE04963.1 - 0.057 14.1 0.9 7.3 7.3 0.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 EGE04963.1 - 0.15 12.2 3.1 0.54 10.4 3.1 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Ctf8 PF09696.10 EGE04965.1 - 3.3e-48 163.6 0.1 3.9e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.25 EGE04966.1 - 8.3e-16 58.3 0.1 4.1e-14 52.9 0.0 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGE04966.1 - 2.3e-08 34.3 0.0 1.5e-05 25.2 0.0 3.0 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGE04966.1 - 7.6e-05 22.9 0.0 0.91 9.6 0.0 3.4 2 2 1 3 3 3 2 Glyoxalase-like domain Pectinesterase PF01095.19 EGE04966.1 - 0.061 12.0 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase RabGAP-TBC PF00566.18 EGE04967.1 - 8e-51 172.7 0.1 8e-51 172.7 0.1 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mago_nashi PF02792.14 EGE04967.1 - 0.88 9.7 4.2 0.33 11.1 0.5 2.0 1 1 1 2 2 2 0 Mago nashi protein DUF2911 PF11138.8 EGE04967.1 - 4.6 7.1 8.2 19 5.1 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2911) PPTA PF01239.22 EGE04968.1 - 2.2e-38 128.9 9.1 1.9e-08 33.8 0.9 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat CtsR_C PF17727.1 EGE04969.1 - 0.0021 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 CtsR C-terminal dimerization domain APH PF01636.23 EGE04970.1 - 4.5e-16 59.5 0.3 7.2e-16 58.8 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE04970.1 - 6.7e-06 25.8 0.4 1.1e-05 25.2 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGE04970.1 - 0.0077 15.6 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF1679 PF07914.11 EGE04970.1 - 0.076 11.9 0.1 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) WD40 PF00400.32 EGE04971.1 - 5.6e-10 39.6 3.9 6.6e-06 26.8 0.0 5.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE04971.1 - 5.4e-08 33.0 0.0 0.00064 20.0 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGE04972.1 - 1.1e-22 80.4 0.5 7e-22 77.8 0.3 2.3 3 0 0 3 3 3 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGE04972.1 - 0.034 14.4 0.0 6.9 7.0 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF212 PF02681.14 EGE04972.1 - 0.052 13.7 1.0 0.12 12.5 1.0 1.5 1 0 0 1 1 1 0 Divergent PAP2 family Bromodomain PF00439.25 EGE04974.1 - 5.3e-20 71.3 0.4 1e-19 70.3 0.4 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EGE04974.1 - 2.1e-18 66.2 0.1 5.1e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation gpW PF02831.15 EGE04974.1 - 0.14 12.1 0.1 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 gpW zf-CSL PF05207.13 EGE04975.1 - 1.9e-21 75.6 0.1 2.3e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Frataxin_Cyay PF01491.16 EGE04976.1 - 1.4e-33 115.2 0.0 1.9e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF1192 PF06698.11 EGE04976.1 - 0.084 12.9 0.5 0.2 11.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Rsbr_N PF08678.10 EGE04976.1 - 0.16 12.1 0.1 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Rsbr N terminal AKAP7_NLS PF10469.9 EGE04977.1 - 2.1e-16 60.5 0.0 3.6e-16 59.7 0.0 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 EGE04979.1 - 3.8e-173 577.0 3.5 5e-173 576.6 3.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Mod_r PF07200.13 EGE04979.1 - 0.0032 17.6 0.1 0.0032 17.6 0.1 2.8 3 0 0 3 3 3 1 Modifier of rudimentary (Mod(r)) protein Ribosomal_L30 PF00327.20 EGE04980.1 - 3.4e-12 46.1 0.2 4.7e-12 45.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.19 EGE04981.1 - 1.5e-12 47.0 0.0 2.9e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EGE04981.1 - 8.6e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGE04981.1 - 2.2e-05 23.6 0.0 0.00013 21.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGE04981.1 - 0.0022 17.2 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE04981.1 - 0.16 10.5 0.0 0.26 9.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PKD_channel PF08016.12 EGE04981.1 - 0.22 10.2 0.1 0.31 9.7 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel Aminotran_1_2 PF00155.21 EGE04982.1 - 7e-92 308.4 0.0 8.3e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SLC12 PF03522.15 EGE04983.1 - 0.61 9.0 12.9 0.65 8.9 12.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Trep_dent_lipo PF09710.10 EGE04983.1 - 3.7 6.4 6.8 4.7 6.0 6.8 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) O-antigen_lig PF13425.6 EGE04983.1 - 4.7 5.9 4.4 5.1 5.8 4.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dicty_REP PF05086.12 EGE04983.1 - 6.2 4.7 10.9 7.4 4.4 10.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2 PF00096.26 EGE04984.1 - 3.2e-19 68.2 28.5 4.1e-05 23.8 1.8 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE04984.1 - 5.6e-17 61.3 25.2 1.5e-06 28.4 1.5 5.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGE04984.1 - 0.00016 21.8 7.3 0.48 10.8 0.1 4.8 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGE04984.1 - 0.0012 19.5 11.1 0.0045 17.7 1.2 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGE04984.1 - 0.025 14.7 2.2 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EGE04984.1 - 0.028 14.2 0.7 0.028 14.2 0.7 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 EGE04984.1 - 0.3 11.5 17.8 0.33 11.4 0.2 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type XPA_N PF01286.18 EGE04984.1 - 1.1 9.4 7.1 0.65 10.1 0.5 2.8 3 0 0 3 3 3 0 XPA protein N-terminal FOXP-CC PF16159.5 EGE04984.1 - 5.7 7.6 21.4 0.18 12.4 0.6 4.6 4 1 1 5 5 5 0 FOXP coiled-coil domain Methyltransf_23 PF13489.6 EGE04985.1 - 6.3e-19 68.4 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE04985.1 - 3e-14 53.4 0.0 5.4e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE04985.1 - 9.5e-12 45.5 0.0 1.9e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE04985.1 - 2e-11 44.5 0.0 3.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE04985.1 - 5.9e-09 35.9 0.0 8.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGE04985.1 - 0.0011 18.3 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Caskin-Pro-rich PF16907.5 EGE04985.1 - 0.094 13.2 4.9 0.22 12.1 4.9 1.6 1 0 0 1 1 1 0 Proline rich region of Caskin proteins Methyltransf_24 PF13578.6 EGE04985.1 - 0.099 13.7 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Prp18 PF02840.15 EGE04985.1 - 0.26 11.3 0.2 0.48 10.5 0.2 1.4 1 0 0 1 1 1 0 Prp18 domain PRIMA1 PF16101.5 EGE04985.1 - 0.99 9.5 3.7 2.2 8.4 3.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 E1-E2_ATPase PF00122.20 EGE04988.1 - 2.2e-38 131.6 9.3 5e-30 104.4 0.4 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE04988.1 - 4.8e-26 91.6 1.5 4.8e-26 91.6 1.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGE04988.1 - 1.9e-24 85.5 0.0 5.3e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE04988.1 - 2.4e-18 67.2 0.9 6.2e-17 62.6 0.9 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE04988.1 - 2.8e-05 24.0 0.7 0.002 17.9 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BRAP2 PF07576.12 EGE04990.1 - 7.4e-34 115.9 0.0 1.4e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGE04990.1 - 1.3e-19 70.3 5.2 1.6e-19 70.0 3.7 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGE04990.1 - 1.5e-08 34.8 9.2 1.5e-08 34.8 9.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE04990.1 - 2.3e-06 27.3 8.7 2.3e-06 27.3 8.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGE04990.1 - 0.00053 19.7 5.2 0.00053 19.7 5.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGE04990.1 - 0.00059 19.6 7.7 0.00059 19.6 7.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE04990.1 - 0.00076 19.3 5.4 0.00076 19.3 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE04990.1 - 0.00076 19.4 7.2 0.00076 19.4 7.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGE04990.1 - 0.00081 19.6 6.4 0.00081 19.6 6.4 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGE04990.1 - 0.0015 18.5 5.7 0.0015 18.5 5.7 2.4 2 1 1 3 3 2 1 RING-type zinc-finger Lectin_N PF03954.14 EGE04990.1 - 0.0028 17.4 2.3 0.0041 16.9 1.3 1.7 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain JAKMIP_CC3 PF16034.5 EGE04990.1 - 0.0028 17.6 7.7 0.0028 17.6 7.7 1.6 2 0 0 2 2 1 1 JAKMIP CC3 domain zf-ANAPC11 PF12861.7 EGE04990.1 - 0.0093 16.0 5.3 0.023 14.7 5.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGE04990.1 - 0.017 15.0 5.0 0.017 15.0 5.0 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MIP-T3_C PF17749.1 EGE04990.1 - 0.044 13.8 7.2 0.094 12.7 7.2 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region zf-RING_6 PF14835.6 EGE04990.1 - 0.067 13.1 7.9 0.023 14.6 4.7 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein ATG16 PF08614.11 EGE04990.1 - 0.14 12.3 20.3 0.026 14.8 13.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EGE04990.1 - 0.18 11.6 20.1 0.014 15.2 15.0 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.18 EGE04990.1 - 0.19 12.0 1.4 3.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper GIT_CC PF16559.5 EGE04990.1 - 0.29 11.0 4.9 0.97 9.3 0.7 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 EGE04990.1 - 0.31 10.9 10.5 0.58 9.9 10.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TerY_C PF15616.6 EGE04990.1 - 0.39 10.8 10.6 1.5 8.9 1.5 2.5 1 1 1 2 2 2 0 TerY-C metal binding domain ZapB PF06005.12 EGE04990.1 - 0.42 11.1 8.3 0.12 12.8 0.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB TLE_N PF03920.15 EGE04990.1 - 0.74 9.9 5.3 1.4 9.0 2.6 2.4 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain TolA_bind_tri PF16331.5 EGE04990.1 - 1.1 9.4 8.0 2.3 8.4 0.9 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation zf-RING_4 PF14570.6 EGE04990.1 - 1.6 8.6 6.2 5 7.0 6.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PRKG1_interact PF15898.5 EGE04990.1 - 1.8 9.5 12.7 1.9 9.4 10.8 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 EGE04990.1 - 2.7 8.1 10.2 3.7 7.6 9.2 1.7 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EGE04990.1 - 3.4 7.1 8.5 6.5 6.2 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1993 PF09351.10 EGE04990.1 - 3.5 7.7 10.5 2.5 8.2 3.5 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1993) TPR_MLP1_2 PF07926.12 EGE04990.1 - 4.2 7.4 22.5 1.6 8.8 19.9 1.6 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein AATF-Che1 PF13339.6 EGE04990.1 - 7 7.3 13.3 18 6.0 0.1 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3450 PF11932.8 EGE04990.1 - 7.8 5.7 15.3 15 4.8 13.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EGE04990.1 - 8.1 6.5 6.4 19 5.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APH PF01636.23 EGE04991.1 - 4.3e-13 49.7 0.0 1.2e-12 48.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE04991.1 - 0.0043 16.7 0.4 0.0083 15.7 0.4 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGE04991.1 - 0.041 13.2 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain ubiquitin PF00240.23 EGE04992.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGE04992.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGE04992.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGE04992.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGE04992.1 - 1.1e-11 45.0 2.8 0.023 15.1 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGE04992.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGE04992.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGE04992.1 - 1.8e-07 31.2 0.3 0.71 9.7 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EGE04992.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 EGE04992.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EGE04992.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EGE04992.1 - 0.00033 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 EGE04992.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 EGE04992.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 EGE04992.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 EGE04992.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 EGE04992.1 - 0.0046 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 EGE04992.1 - 0.0088 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 EGE04992.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 EGE04992.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 EGE04992.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EGE04992.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 EGE04992.1 - 0.061 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 EGE04992.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 EGE04992.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 EGE04992.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EGE04992.1 - 0.27 10.9 1.5 72 3.1 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 EGE04992.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 EGE04992.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 EGE04992.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 EGE04992.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 EGE04993.1 - 0.0045 17.1 7.8 0.01 16.0 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Androgen_recep PF02166.16 EGE04993.1 - 2.3 6.9 13.8 4.2 6.1 2.4 2.4 2 0 0 2 2 2 0 Androgen receptor Prenyltrans PF00432.21 EGE04994.1 - 1.6e-31 107.7 36.8 1.4e-12 47.1 1.1 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SR-25 PF10500.9 EGE04994.1 - 0.061 12.9 7.5 0.092 12.3 7.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein eIF3_subunit PF08597.10 EGE04994.1 - 0.29 11.0 7.6 0.4 10.6 7.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_S49_N PF08496.10 EGE04994.1 - 2 8.4 5.8 3.2 7.8 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3464 PF11947.8 EGE04994.1 - 4.4 7.0 5.5 7.6 6.3 5.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4692 PF15763.5 EGE04995.1 - 0.13 12.7 0.8 0.25 11.8 0.8 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) dsrm PF00035.26 EGE04995.1 - 0.19 12.5 0.0 0.31 11.8 0.0 1.3 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF4448 PF14610.6 EGE04999.1 - 6.7e-37 127.1 0.0 9.9e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) LapA_dom PF06305.11 EGE04999.1 - 0.0017 18.1 0.6 0.0041 16.9 0.6 1.6 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Alpha_GJ PF03229.13 EGE04999.1 - 1.7 9.2 15.4 5.4 7.6 11.8 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mito_fiss_reg PF05308.11 EGE04999.1 - 3.6 7.6 5.6 45 4.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Hpt PF01627.23 EGE05000.1 - 3.1e-14 53.0 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Ribonuc_L-PSP PF01042.21 EGE05000.1 - 0.16 12.0 0.0 0.49 10.4 0.0 1.8 1 1 1 2 2 2 0 Endoribonuclease L-PSP APH PF01636.23 EGE05001.1 - 9.7e-17 61.7 0.0 1.2e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE05001.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EGE05001.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 EGE05001.1 - 0.14 11.5 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain HMGL-like PF00682.19 EGE05002.1 - 4.4e-79 265.8 0.3 6.1e-79 265.3 0.3 1.2 1 0 0 1 1 1 1 HMGL-like PTH2 PF01981.16 EGE05004.1 - 1.3e-42 144.8 0.0 1.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribosomal_60s PF00428.19 EGE05004.1 - 0.014 15.9 1.2 0.025 15.2 1.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM176 PF14851.6 EGE05004.1 - 0.074 12.7 1.6 0.14 11.8 1.6 1.4 1 0 0 1 1 1 0 FAM176 family GOLD_2 PF13897.6 EGE05004.1 - 0.084 13.4 0.2 0.12 12.8 0.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sec23_trunk PF04811.15 EGE05004.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain NOA36 PF06524.12 EGE05004.1 - 0.24 10.7 6.0 0.35 10.2 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGE05004.1 - 0.26 11.7 8.8 0.42 11.0 8.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EGE05004.1 - 2.6 6.1 7.6 3.2 5.7 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi SART-1 PF03343.13 EGE05005.1 - 2.6e-185 617.6 61.0 3e-185 617.4 61.0 1.0 1 0 0 1 1 1 1 SART-1 family FeoC PF09012.10 EGE05005.1 - 0.0081 16.2 1.4 3.5 7.8 0.1 2.9 3 0 0 3 3 3 2 FeoC like transcriptional regulator WD40 PF00400.32 EGE05006.1 - 1.7e-16 60.3 8.3 0.00031 21.5 0.0 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGE05006.1 - 0.00074 18.4 0.0 0.68 8.6 0.0 2.2 1 1 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EGE05006.1 - 0.003 17.8 0.0 3.5 8.0 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGE05006.1 - 0.068 13.7 0.1 22 5.7 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain APH PF01636.23 EGE05009.1 - 4.5e-11 43.1 1.8 7e-09 35.9 0.3 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Prophage_tail PF06605.11 EGE05009.1 - 0.043 13.0 0.0 0.25 10.5 0.0 1.7 1 1 1 2 2 2 0 Prophage endopeptidase tail DUF155 PF02582.14 EGE05010.1 - 5.1e-53 179.8 0.0 1.1e-52 178.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Aldedh PF00171.22 EGE05011.1 - 5.7e-144 480.1 0.2 6.7e-144 479.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGE05011.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.25 EGE05013.1 - 5e-11 42.5 0.0 6.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05013.1 - 3.4e-06 26.5 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 EGE05014.1 - 2e-33 114.1 49.1 4.9e-06 27.0 1.5 12.8 13 1 1 14 14 14 8 Sel1 repeat Mei5 PF10376.9 EGE05015.1 - 3.7e-08 33.5 1.3 3.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Double-strand recombination repair protein TFIIA PF03153.13 EGE05015.1 - 0.022 14.8 8.0 0.027 14.5 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4140 PF13600.6 EGE05015.1 - 0.086 13.3 0.1 0.086 13.3 0.1 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Dermcidin PF15291.6 EGE05015.1 - 0.12 12.9 0.4 6.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide DUF4407 PF14362.6 EGE05015.1 - 1.1 8.5 7.0 2.9 7.2 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Dus PF01207.17 EGE05020.1 - 1.8e-42 145.5 0.0 5.3e-30 104.6 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 EGE05020.1 - 0.00049 19.9 2.9 0.03 14.2 0.4 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE05020.1 - 0.0025 17.8 7.2 0.076 13.1 1.8 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGE05020.1 - 0.0053 16.5 1.0 0.0053 16.5 1.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Kelch_4 PF13418.6 EGE05021.1 - 2.1e-27 94.9 5.8 8.3e-07 28.9 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGE05021.1 - 6.3e-25 86.7 0.2 1.1e-05 25.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EGE05021.1 - 7e-23 79.7 1.2 4.2e-07 29.7 0.1 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGE05021.1 - 1.2e-22 79.3 3.4 1.3e-05 25.3 0.0 5.3 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGE05021.1 - 1e-20 73.0 1.6 6.9e-06 25.5 0.1 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EGE05021.1 - 6.5e-20 70.9 12.7 2.3e-07 31.0 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 EGE05021.1 - 5.3e-08 33.1 0.0 9.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Choline_kinase PF01633.20 EGE05022.1 - 8.5e-06 25.5 1.0 1.5e-05 24.7 1.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGE05022.1 - 9.7e-06 25.7 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGE05022.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGE05022.1 - 0.088 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ANAPC4_WD40 PF12894.7 EGE05023.1 - 1e-09 38.5 0.5 5.9e-06 26.5 0.1 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE05023.1 - 0.013 16.3 8.0 0.29 12.1 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Kelch_3 PF13415.6 EGE05024.1 - 3e-19 68.8 1.1 8.3e-11 41.9 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGE05024.1 - 3.8e-15 55.6 0.5 4.4e-05 23.4 0.1 4.3 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE05024.1 - 2.1e-13 50.0 0.3 0.016 15.4 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EGE05024.1 - 3.9e-13 48.8 0.1 0.0076 15.8 0.0 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EGE05024.1 - 2.9e-09 36.5 3.0 0.00066 19.6 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 EGE05024.1 - 3e-09 36.6 7.6 0.0022 17.9 0.0 4.3 4 1 0 4 4 4 3 Kelch motif mRNA_triPase PF02940.15 EGE05025.1 - 1.6e-61 207.9 0.0 1.9e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain WD40 PF00400.32 EGE05027.1 - 2.2e-15 56.7 3.4 3.3e-05 24.5 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box PF00646.33 EGE05031.1 - 3 7.8 5.5 2.2 8.2 0.1 3.1 3 0 0 3 3 3 0 F-box domain Zn_clus PF00172.18 EGE05032.1 - 2.7e-09 37.0 6.6 2.7e-09 37.0 6.6 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE05032.1 - 2e-05 23.6 0.2 2.7e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain UbiA PF01040.18 EGE05033.1 - 1.3e-56 191.7 17.0 1.3e-56 191.7 17.0 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family PQ-loop PF04193.14 EGE05034.1 - 4.4e-19 68.0 13.8 1.9e-12 46.7 1.6 3.2 3 0 0 3 3 3 2 PQ loop repeat Med8 PF10232.9 EGE05035.1 - 3.3e-61 206.9 1.0 4.6e-61 206.4 1.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 BSP_II PF05432.11 EGE05035.1 - 0.045 13.4 2.3 0.061 13.0 2.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TMEM154 PF15102.6 EGE05036.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TF_Otx PF03529.13 EGE05038.1 - 0.26 11.7 7.9 0.36 11.2 5.7 2.1 1 1 0 2 2 2 0 Otx1 transcription factor DUF3136 PF11334.8 EGE05039.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) FAD_binding_4 PF01565.23 EGE05040.1 - 3.3e-21 75.5 0.4 5.7e-21 74.7 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE05040.1 - 0.016 15.3 0.1 0.14 12.3 0.0 2.6 4 0 0 4 4 4 0 Berberine and berberine like Peptidase_S9 PF00326.21 EGE05041.1 - 0.038 13.5 2.6 0.17 11.3 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGE05041.1 - 0.11 12.1 0.3 0.3 10.7 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE05041.1 - 0.15 11.3 0.0 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGE05041.1 - 0.15 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TMF_TATA_bd PF12325.8 EGE05042.1 - 0.0061 16.8 6.1 0.0061 16.8 6.1 4.2 3 2 1 4 4 4 1 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 EGE05042.1 - 0.022 15.0 4.2 0.022 15.0 4.2 4.3 4 1 1 5 5 5 0 ABC transporter C-terminal domain ESCRT-II PF05871.12 EGE05042.1 - 0.026 14.8 0.4 0.073 13.3 0.4 1.8 1 0 0 1 1 1 0 ESCRT-II complex subunit ApoC-I PF04691.12 EGE05042.1 - 0.099 12.6 0.4 0.38 10.7 0.4 2.1 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) FlgN PF05130.12 EGE05042.1 - 0.11 13.0 21.0 0.8 10.2 2.1 3.6 3 1 1 4 4 4 0 FlgN protein DNA_repr_REX1B PF14966.6 EGE05042.1 - 0.19 12.4 5.2 0.094 13.4 1.7 2.3 2 1 0 2 2 2 0 DNA repair REX1-B DUF465 PF04325.13 EGE05042.1 - 0.19 11.8 7.0 1.2 9.3 4.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Prominin PF05478.11 EGE05042.1 - 0.3 9.0 9.9 0.11 10.5 4.6 2.0 2 0 0 2 2 2 0 Prominin UPF0184 PF03670.13 EGE05042.1 - 0.74 10.3 5.5 2.4 8.6 0.2 3.0 3 0 0 3 3 2 0 Uncharacterised protein family (UPF0184) TolA_bind_tri PF16331.5 EGE05042.1 - 1.3 9.1 15.9 0.13 12.3 4.4 3.2 3 0 0 3 3 2 0 TolA binding protein trimerisation Fez1 PF06818.15 EGE05042.1 - 1.5 9.2 24.2 0.96 9.9 3.9 2.6 3 0 0 3 3 2 0 Fez1 Med4 PF10018.9 EGE05042.1 - 1.6 8.4 11.8 0.23 11.1 4.5 2.7 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-H PF05837.12 EGE05042.1 - 1.8 9.0 22.2 0.68 10.4 5.8 4.2 3 2 0 3 3 2 0 Centromere protein H (CENP-H) MutS_IV PF05190.18 EGE05042.1 - 1.9 8.9 8.3 7.4 7.0 0.3 4.0 4 0 0 4 4 4 0 MutS family domain IV COG2 PF06148.11 EGE05042.1 - 2.5 8.2 11.7 0.11 12.6 2.4 2.9 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1515 PF07439.11 EGE05042.1 - 2.5 8.2 10.1 0.15 12.1 2.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) SKA2 PF16740.5 EGE05042.1 - 2.8 7.8 14.7 0.077 12.8 2.3 3.5 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 EGE05042.1 - 3.3 6.5 24.5 0.17 10.7 8.0 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein Osmo_CC PF08946.10 EGE05042.1 - 3.8 7.8 12.5 0.22 11.8 2.3 3.1 3 0 0 3 3 2 0 Osmosensory transporter coiled coil Allexi_40kDa PF05549.11 EGE05042.1 - 4.5 6.7 14.5 0.13 11.8 2.3 3.1 3 0 0 3 3 3 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.22 EGE05042.1 - 5.7 7.2 19.6 0.48 10.7 6.4 3.9 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 EGE05042.1 - 6 6.1 9.3 0.072 12.4 0.5 2.1 3 0 0 3 3 2 0 CorA-like Mg2+ transporter protein FAA_hydro_N_2 PF18288.1 EGE05042.1 - 7.3 7.1 6.7 64 4.1 0.0 3.9 5 1 0 5 5 4 0 Fumarylacetoacetase N-terminal domain 2 APG6_N PF17675.1 EGE05042.1 - 7.4 7.1 29.3 0.85 10.1 8.7 4.0 2 1 2 4 4 4 0 Apg6 coiled-coil region RPN2_C PF18004.1 EGE05043.1 - 8.5e-58 194.8 7.9 8.5e-58 194.8 7.9 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGE05043.1 - 4e-32 109.0 25.2 7.7e-10 38.7 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGE05043.1 - 4e-22 78.4 0.5 6.6e-16 58.5 0.0 3.8 3 1 1 4 4 3 2 HEAT repeats HEAT_EZ PF13513.6 EGE05043.1 - 8.7e-09 35.7 0.1 0.019 15.5 0.0 4.0 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGE05043.1 - 4e-06 26.6 0.1 1.8 9.0 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EGE05043.1 - 0.0025 17.9 0.0 0.18 11.9 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EGE05043.1 - 0.0079 16.8 2.3 1.1 10.2 0.0 3.9 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat GCIP PF13324.6 EGE05043.1 - 0.074 12.6 5.3 0.15 11.7 5.3 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 EGE05043.1 - 2.3 7.1 8.9 1.5 7.7 1.4 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 EGE05043.1 - 3.6 6.0 7.6 6.1 5.3 7.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UBN_AB PF14075.6 EGE05043.1 - 5.8 6.6 10.9 0.022 14.5 1.0 1.9 2 0 0 2 2 1 0 Ubinuclein conserved middle domain Acyl-CoA_dh_1 PF00441.24 EGE05044.1 - 2.2e-42 144.8 0.3 3.2e-42 144.3 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGE05044.1 - 2.5e-21 75.7 0.1 4.1e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGE05044.1 - 5.5e-20 72.1 0.0 1.1e-19 71.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EGE05044.1 - 6.2e-15 55.1 0.3 1.2e-14 54.1 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EGE05044.1 - 6e-10 39.5 0.0 9.9e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spt5-NGN PF03439.13 EGE05045.1 - 1.6e-23 82.4 0.0 3e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EGE05045.1 - 3.4e-19 69.2 18.2 3.4e-19 69.2 18.2 3.8 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 EGE05045.1 - 1.5e-17 64.4 10.7 1.5e-17 64.4 10.7 3.8 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EGE05045.1 - 4.3e-12 45.5 7.0 0.0025 17.7 1.6 4.3 4 0 0 4 4 4 3 KOW motif DUF3912 PF13051.6 EGE05045.1 - 0.0001 22.5 4.0 0.011 16.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3912) CS PF04969.16 EGE05046.1 - 1.6e-17 64.3 0.1 3.3e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 CS domain CE2_N PF17996.1 EGE05046.1 - 0.093 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Spore_GerAC PF05504.11 EGE05046.1 - 0.11 12.8 1.7 0.52 10.5 1.7 1.9 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Anoctamin PF04547.12 EGE05047.1 - 1.5e-109 366.8 10.5 2e-109 366.4 10.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Pex2_Pex12 PF04757.14 EGE05047.1 - 0.025 14.2 0.0 0.025 14.2 0.0 2.4 3 0 0 3 3 3 0 Pex2 / Pex12 amino terminal region YMF19 PF02326.15 EGE05047.1 - 0.32 11.8 2.7 15 6.5 0.8 3.5 3 0 0 3 3 3 0 Plant ATP synthase F0 ERM PF00769.19 EGE05048.1 - 3.7e-05 23.6 23.6 9.1e-05 22.4 23.6 1.6 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APH PF01636.23 EGE05048.1 - 8.5e-05 22.6 0.1 8.5e-05 22.6 0.1 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 EGE05048.1 - 0.0013 18.7 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase PF00069.25 EGE05048.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGE05048.1 - 0.0063 16.1 0.5 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase K_channel_TID PF07941.11 EGE05048.1 - 0.1 13.1 0.2 0.1 13.1 0.2 3.2 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Golgin_A5 PF09787.9 EGE05048.1 - 1.9 7.9 25.0 3 7.2 25.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 EGE05048.1 - 5.9 7.4 31.6 13 6.3 31.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EGE05048.1 - 7.9 5.5 14.6 13 4.8 14.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF874 PF05917.11 EGE05048.1 - 8.3 5.3 9.8 13 4.7 9.8 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF4175 PF13779.6 EGE05050.1 - 1.8 6.4 26.1 2 6.2 26.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Actin PF00022.19 EGE05051.1 - 2.1e-54 184.7 0.0 1.9e-51 175.0 0.0 2.4 1 1 0 1 1 1 1 Actin DASH_Dad4 PF08650.10 EGE05052.1 - 4.4e-31 106.7 5.6 5e-31 106.5 5.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 EGE05052.1 - 0.0099 16.0 0.4 0.013 15.7 0.4 1.2 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.10 EGE05052.1 - 0.053 13.7 2.5 0.081 13.1 2.5 1.3 1 1 0 1 1 1 0 DASH complex subunit Dad1 DUF2443 PF10398.9 EGE05052.1 - 0.054 13.5 0.2 0.09 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Biotin_carb_C PF02785.19 EGE05052.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain YL1_C PF08265.11 EGE05053.1 - 5.6e-17 61.2 0.3 9e-17 60.5 0.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Gag_p12 PF01141.18 EGE05053.1 - 0.35 11.2 3.0 0.25 11.7 0.8 2.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Got1 PF04178.12 EGE05054.1 - 3.3e-14 53.3 13.9 4.4e-14 52.9 13.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 EGE05054.1 - 7.8 5.8 6.0 3.9 6.8 3.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Profilin PF00235.19 EGE05055.1 - 7e-47 158.9 0.0 7.8e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 Profilin XTBD PF11952.8 EGE05057.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Sec63 PF02889.16 EGE05058.1 - 2.1e-128 426.9 0.0 4.2e-77 258.8 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGE05058.1 - 3.3e-53 180.0 1.2 2.3e-26 92.6 1.5 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGE05058.1 - 6.4e-23 81.6 0.0 4.5e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGE05058.1 - 6.7e-16 58.6 0.1 4.1e-07 30.3 0.0 4.4 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGE05058.1 - 1.2e-07 32.1 2.0 0.0033 17.7 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EGE05058.1 - 2.2e-07 30.8 0.3 0.0012 18.6 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGE05058.1 - 2.5e-05 24.6 1.6 0.0019 18.5 1.2 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGE05058.1 - 0.003 16.7 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein Helicase_PWI PF18149.1 EGE05058.1 - 0.0031 17.7 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal helicase PWI domain PhoH PF02562.16 EGE05058.1 - 0.011 15.2 0.0 0.69 9.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 EGE05058.1 - 0.054 13.2 0.1 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGE05058.1 - 0.07 12.6 0.1 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DEK_C PF08766.11 EGE05058.1 - 0.074 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 DEK C terminal domain TniB PF05621.11 EGE05058.1 - 0.14 11.6 3.5 31 3.9 0.4 3.8 3 1 0 4 4 4 0 Bacterial TniB protein Synaptobrevin PF00957.21 EGE05059.1 - 7.7e-14 51.3 0.2 1.2e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGE05059.1 - 2e-10 40.6 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MFS_1 PF07690.16 EGE05061.1 - 1.2e-21 77.0 57.2 6.3e-15 54.9 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGE05061.1 - 9.9e-06 24.4 6.5 9.9e-06 24.4 6.5 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein CDH-cyt PF16010.5 EGE05061.1 - 0.0048 16.6 1.2 0.0081 15.9 1.2 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF5337 PF17272.2 EGE05061.1 - 0.32 10.8 4.1 0.21 11.5 0.8 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Ras PF00071.22 EGE05062.1 - 5.4e-35 120.4 0.0 6.7e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE05062.1 - 6.7e-29 100.5 0.0 9e-29 100.1 0.0 1.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE05062.1 - 6.2e-11 42.0 0.0 7.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE05062.1 - 5.7e-05 23.2 0.0 8.5e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE05062.1 - 0.00029 21.3 0.1 0.00038 20.9 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGE05062.1 - 0.0023 18.2 0.1 0.0082 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EGE05062.1 - 0.0035 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGE05062.1 - 0.022 14.1 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 EGE05062.1 - 0.034 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EGE05062.1 - 0.036 14.1 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE05062.1 - 0.065 13.1 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EGE05062.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGE05062.1 - 0.07 13.4 0.2 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGE05062.1 - 0.076 12.5 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGE05062.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 EGE05062.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EGE05062.1 - 0.18 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FMN_dh PF01070.18 EGE05063.1 - 7.2e-121 403.4 0.2 8.5e-121 403.2 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EGE05063.1 - 3.9e-20 71.8 0.0 8.1e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EGE05063.1 - 5e-06 25.9 0.1 7.8e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EGE05063.1 - 1.4e-05 24.7 0.5 3.4e-05 23.4 0.3 1.7 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 EGE05063.1 - 0.00066 18.8 2.4 0.0019 17.3 0.1 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGE05063.1 - 0.042 13.3 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein Metallophos PF00149.28 EGE05064.1 - 3.3e-15 57.1 2.7 4.4e-15 56.7 2.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE05064.1 - 1.2e-07 32.1 1.0 2e-06 28.1 1.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.6 EGE05064.1 - 0.051 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 MutL protein Pkinase PF00069.25 EGE05065.1 - 2.9e-40 138.3 0.0 7.9e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05065.1 - 6.1e-13 48.6 0.1 2.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE05065.1 - 0.12 11.1 1.7 0.11 11.3 0.2 1.7 1 1 1 2 2 2 0 Fungal protein kinase Bud13 PF09736.9 EGE05066.1 - 7.3e-19 68.6 0.3 7.3e-19 68.6 0.3 3.4 2 2 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex SPATIAL PF15256.6 EGE05066.1 - 3 8.1 8.7 0.34 11.2 3.6 1.9 2 0 0 2 2 2 0 SPATIAL Ferlin_C PF16165.5 EGE05066.1 - 4.2 7.3 7.6 2 8.4 4.4 1.9 2 0 0 2 2 2 0 Ferlin C-terminus DUF4407 PF14362.6 EGE05066.1 - 5.1 6.4 15.0 8 5.7 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop16 PF09420.10 EGE05066.1 - 6.1 6.8 14.7 0.18 11.8 7.7 1.9 1 1 0 2 2 2 0 Ribosome biogenesis protein Nop16 DUF812 PF05667.11 EGE05067.1 - 0.015 14.2 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.9 EGE05067.1 - 0.041 12.4 0.7 0.052 12.1 0.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF1192 PF06698.11 EGE05067.1 - 0.11 12.6 1.5 0.21 11.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DNA_binding_1 PF01035.20 EGE05068.1 - 3.6e-26 91.1 0.0 4.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PHINT_rpt PF14882.6 EGE05068.1 - 0.13 12.5 0.2 0.28 11.5 0.2 1.5 1 0 0 1 1 1 0 Phage-integrase repeat unit HNH_2 PF13391.6 EGE05069.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease Fungal_trans_2 PF11951.8 EGE05071.1 - 2e-96 323.1 1.6 2.4e-96 322.9 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05071.1 - 8.9e-11 41.7 10.0 8.9e-11 41.7 10.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.9 EGE05072.1 - 1.6e-47 160.6 0.7 2.2e-47 160.2 0.7 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF5423 PF17461.2 EGE05072.1 - 0.33 9.8 6.1 0.54 9.1 6.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) AA_permease PF00324.21 EGE05073.1 - 7e-123 410.7 48.2 7.9e-123 410.6 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05073.1 - 4.5e-31 108.1 52.9 5.5e-31 107.8 52.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05074.1 - 2.4e-63 214.5 50.1 2.9e-63 214.2 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE05074.1 - 3e-10 39.3 45.3 4e-10 38.9 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.25 EGE05076.1 - 1.2e-17 64.2 0.0 1.4e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE05076.1 - 2.1e-08 34.4 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE05076.1 - 7.1e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGE05076.1 - 5.8e-07 29.5 0.0 9.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGE05076.1 - 1.5e-06 28.9 0.0 1.8e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGE05076.1 - 0.012 15.1 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGE05076.1 - 0.025 14.7 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGE05076.1 - 0.058 13.5 0.0 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain OB_aCoA_assoc PF01796.17 EGE05076.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated GRIP PF01465.20 EGE05077.1 - 7.9e-15 54.5 0.2 1.7e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 GRIP domain CALCOCO1 PF07888.11 EGE05077.1 - 5.6e-06 25.5 137.8 0.0018 17.2 24.0 5.8 3 1 2 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like Baculo_PEP_C PF04513.12 EGE05077.1 - 0.00068 19.7 41.4 0.2 11.7 4.9 7.1 6 2 1 7 7 7 3 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 EGE05077.1 - 0.0011 18.6 11.9 0.0011 18.6 11.9 8.0 4 2 4 8 8 7 2 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EGE05077.1 - 0.0016 17.8 131.6 0.029 13.7 10.6 9.2 4 2 5 10 10 10 4 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EGE05077.1 - 0.0022 18.2 10.4 0.0022 18.2 10.4 11.5 6 3 7 13 13 11 3 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EGE05077.1 - 0.003 16.5 137.2 0.035 13.0 17.9 8.0 3 2 4 7 7 7 4 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EGE05077.1 - 0.0046 17.0 147.1 0.021 14.8 13.6 10.0 3 2 6 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EGE05077.1 - 0.035 13.6 134.6 0.099 12.1 23.1 8.5 3 2 5 8 8 8 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 EGE05077.1 - 0.096 11.0 126.9 0.0058 15.1 7.0 6.2 3 2 2 5 5 5 0 Mitotic checkpoint protein TolA_bind_tri PF16331.5 EGE05077.1 - 0.11 12.6 70.3 0.12 12.4 0.1 11.2 7 4 3 10 10 10 0 TolA binding protein trimerisation Bap31_Bap29_C PF18035.1 EGE05077.1 - 0.19 11.8 0.1 0.19 11.8 0.1 10.0 9 2 1 10 10 9 0 Bap31/Bap29 cytoplasmic coiled-coil domain Myosin_tail_1 PF01576.19 EGE05077.1 - 0.31 8.8 144.9 0.015 13.2 18.0 3.5 3 1 0 3 3 3 0 Myosin tail AAA_13 PF13166.6 EGE05077.1 - 0.72 8.4 103.1 0.33 9.5 18.9 6.2 3 1 2 5 5 5 0 AAA domain FPP PF05911.11 EGE05077.1 - 0.83 7.8 134.5 0.34 9.0 17.2 6.6 1 1 5 7 7 7 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 EGE05077.1 - 0.91 9.0 124.9 0.29 10.7 13.8 7.0 3 2 3 6 6 6 0 Intermediate filament protein VGPC1_C PF16799.5 EGE05077.1 - 0.91 9.5 17.0 0.24 11.4 0.8 4.7 4 0 0 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF641 PF04859.12 EGE05077.1 - 2.1 8.7 104.7 0.037 14.3 9.1 10.4 6 3 4 10 10 9 0 Plant protein of unknown function (DUF641) EzrA PF06160.12 EGE05077.1 - 2.1 6.4 104.2 0.14 10.3 45.4 7.1 3 2 3 6 6 6 0 Septation ring formation regulator, EzrA FlaC_arch PF05377.11 EGE05077.1 - 5.2 7.5 78.0 0.64 10.5 1.5 13.2 9 4 3 12 12 12 0 Flagella accessory protein C (FlaC) FAA_hydro_N_2 PF18288.1 EGE05077.1 - 7 7.1 9.4 0.75 10.3 0.4 4.2 3 1 1 4 4 3 0 Fumarylacetoacetase N-terminal domain 2 zinc_ribbon_10 PF10058.9 EGE05078.1 - 1.1e-18 66.6 0.1 1.8e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein cNMP_binding PF00027.29 EGE05079.1 - 2.2e-29 101.4 2.6 2e-19 69.5 0.0 5.5 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EGE05079.1 - 5.3e-17 62.7 10.7 6.2e-16 59.2 7.8 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase DAO PF01266.24 EGE05080.1 - 3.8e-30 105.7 0.0 5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EGE05080.1 - 0.00011 22.4 0.0 0.00051 20.3 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 EGE05080.1 - 0.0018 18.3 0.0 0.065 13.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGE05080.1 - 0.0089 16.2 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGE05080.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EGE05080.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 EGE05080.1 - 0.19 10.9 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_33 PF10017.9 EGE05081.1 - 7.8e-72 242.0 0.0 1e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.8 EGE05082.1 - 3.6e-28 98.5 0.3 4.9e-28 98.0 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGE05083.1 - 2.1 9.0 9.9 2.9 8.5 0.5 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE05083.1 - 2.3 9.3 5.5 4.9 8.2 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger ISN1 PF06437.11 EGE05085.1 - 8.8e-196 650.7 0.0 9.9e-196 650.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase eIF-5a PF01287.20 EGE05085.1 - 0.028 14.5 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Med17 PF10156.9 EGE05086.1 - 5.2e-99 332.0 1.6 8.5e-99 331.3 1.3 1.4 1 1 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 EGE05087.1 - 3.3e-192 636.9 0.1 1.4e-106 356.0 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EGE05087.1 - 0.043 13.4 0.1 0.17 11.5 0.1 2.0 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_76 PF03663.14 EGE05088.1 - 2e-160 534.3 7.6 2.3e-160 534.1 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGE05088.1 - 3.3e-05 23.1 8.1 0.0028 16.8 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 MARVEL PF01284.23 EGE05089.1 - 1.2e-10 41.6 9.6 1.5e-10 41.2 9.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4181 PF13789.6 EGE05089.1 - 0.029 14.6 2.8 0.033 14.5 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) RAC_head PF16717.5 EGE05090.1 - 2.2e-30 105.5 2.0 2.2e-30 105.5 2.0 3.1 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EGE05090.1 - 7.9e-18 64.3 0.9 2e-17 63.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.15 EGE05091.1 - 4.3e-07 29.9 0.1 7.4e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 EGE05092.1 - 3.6e-10 39.5 0.0 7.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE05092.1 - 0.0025 17.8 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGE05092.1 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sterol_MT_C PF08498.10 EGE05093.1 - 6.8e-28 96.8 0.3 1.1e-27 96.1 0.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGE05093.1 - 3.3e-18 66.1 0.0 5.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE05093.1 - 4.4e-18 65.8 0.0 8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05093.1 - 1.5e-15 57.3 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE05093.1 - 3.4e-11 43.3 0.0 5.6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGE05093.1 - 5e-11 42.4 0.0 7.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EGE05093.1 - 9.5e-11 42.3 0.0 2.5e-10 41.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE05093.1 - 2.7e-09 36.7 0.0 4.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGE05093.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EGE05093.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EGE05093.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGE05093.1 - 0.0034 17.0 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGE05093.1 - 0.0056 16.7 1.2 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE05093.1 - 0.0064 16.0 0.0 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.20 EGE05093.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EGE05093.1 - 0.062 12.6 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_24 PF13578.6 EGE05093.1 - 0.14 13.2 0.0 0.45 11.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain zf-MYND PF01753.18 EGE05094.1 - 1.6e-07 31.3 10.6 1.6e-07 31.3 10.6 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EGE05094.1 - 1.4 8.8 15.0 0.2 11.6 9.4 2.4 2 0 0 2 2 2 0 HIT zinc finger Peptidase_S8 PF00082.22 EGE05095.1 - 3e-19 69.4 16.1 8.5e-19 67.9 16.1 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE05095.1 - 1.6e-14 54.3 0.0 2.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 MFS_1 PF07690.16 EGE05096.1 - 2.5e-41 141.8 51.7 3.6e-40 138.0 51.7 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3377 PF11857.8 EGE05096.1 - 0.037 14.0 0.1 0.037 14.0 0.1 3.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3377) Strabismus PF06638.11 EGE05096.1 - 0.053 12.2 2.5 0.081 11.6 2.5 1.2 1 0 0 1 1 1 0 Strabismus protein Spore_YhaL PF14147.6 EGE05096.1 - 8.5 6.2 9.9 6.9 6.5 0.2 3.2 3 0 0 3 3 3 0 Sporulation protein YhaL Fungal_trans PF04082.18 EGE05097.1 - 7.3e-16 58.0 0.0 1.1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05097.1 - 2.8e-08 33.7 9.3 4.9e-08 33.0 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 EGE05098.1 - 1.6e-58 198.5 0.1 2.3e-58 198.0 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EGE05098.1 - 6.5e-21 73.9 0.1 4.9e-20 71.1 0.0 2.2 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EGE05098.1 - 4e-08 33.2 0.0 6.3e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EGE05098.1 - 0.039 14.7 0.0 0.11 13.3 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 EGE05098.1 - 0.079 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 EGE05098.1 - 0.093 11.3 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Amidohydro_1 PF01979.20 EGE05099.1 - 4.9e-72 243.1 0.0 5.8e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGE05099.1 - 8.1e-09 35.5 1.0 4.3e-06 26.5 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family A_deaminase PF00962.22 EGE05099.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toxin_29 PF08116.11 EGE05099.1 - 0.035 14.1 0.3 0.1 12.6 0.3 1.8 1 0 0 1 1 1 0 PhTx neurotoxin family tRNA_int_end_N2 PF12928.7 EGE05099.1 - 0.043 14.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 tRNA-splicing endonuclease subunit sen54 N-term DUF3466 PF11949.8 EGE05099.1 - 0.098 11.2 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) GDC-P PF02347.16 EGE05103.1 - 5.1e-115 384.7 0.0 5e-102 341.9 0.0 3.3 2 2 1 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EGE05103.1 - 1.8e-07 30.8 0.1 6.9e-07 28.8 0.1 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGE05103.1 - 0.00083 18.4 0.0 0.0041 16.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGE05103.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TraF_2 PF13729.6 EGE05103.1 - 0.22 10.9 0.2 0.46 9.8 0.2 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein TMEM51 PF15345.6 EGE05104.1 - 3.6e-05 23.7 1.5 4.9e-05 23.3 0.0 1.9 2 1 1 3 3 3 1 Transmembrane protein 51 PRIMA1 PF16101.5 EGE05104.1 - 5.7 7.0 0.0 5.7 7.0 0.0 2.7 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Pyridoxal_deC PF00282.19 EGE05105.1 - 8.3e-105 350.6 0.0 9.7e-105 350.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGE05105.1 - 0.00027 20.3 0.0 0.00071 18.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Abhydrolase_6 PF12697.7 EGE05106.1 - 5.7e-14 53.2 0.2 6.7e-14 53.0 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family MBOAT_2 PF13813.6 EGE05107.1 - 2.8e-23 82.0 0.3 5.5e-23 81.1 0.3 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glyco_hydro_65N PF03636.15 EGE05108.1 - 1.4e-34 119.7 0.0 2.3e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 EGE05108.1 - 6e-26 91.2 1.6 1.7e-20 73.2 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 EGE05108.1 - 5.6e-05 23.0 0.1 0.00017 21.4 0.1 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain SMC_Nse1 PF07574.13 EGE05109.1 - 1.5e-69 233.8 0.2 1.9e-69 233.5 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EGE05109.1 - 3.4e-12 46.5 9.9 7.4e-12 45.4 9.9 1.6 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 EGE05109.1 - 0.0014 18.9 8.2 0.0024 18.2 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain PaaX PF07848.12 EGE05109.1 - 0.0046 17.1 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 PaaX-like protein zf-ANAPC11 PF12861.7 EGE05109.1 - 0.01 15.9 2.1 0.019 15.0 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AbiEi_4 PF13338.6 EGE05109.1 - 0.014 15.6 0.9 0.048 13.8 0.2 2.3 2 1 1 3 3 3 0 Transcriptional regulator, AbiEi antitoxin zf-rbx1 PF12678.7 EGE05109.1 - 0.096 13.0 5.3 0.19 12.0 5.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain CtsR_C PF17727.1 EGE05109.1 - 0.1 12.8 0.0 3.1 8.0 0.0 2.8 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain Baculo_IE-1 PF05290.11 EGE05109.1 - 0.67 9.9 4.4 1.5 8.8 3.6 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-HC5HC2H_2 PF13832.6 EGE05109.1 - 0.82 9.9 9.2 3.6 7.8 9.3 2.0 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_2 PF13923.6 EGE05109.1 - 0.96 9.4 7.3 1.7 8.5 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 EGE05109.1 - 1 9.7 11.0 3 8.2 9.8 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 EGE05109.1 - 1.1 8.9 7.2 2 8.1 7.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGE05109.1 - 1.8 8.5 8.0 3.6 7.5 8.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE05109.1 - 2.8 8.0 9.6 5.2 7.1 9.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DAO PF01266.24 EGE05110.1 - 8.1e-44 150.6 0.7 9.3e-44 150.4 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGE05110.1 - 0.0054 17.3 0.0 0.048 14.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE05110.1 - 0.0087 16.3 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGE05110.1 - 0.0092 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGE05110.1 - 0.038 13.2 0.0 0.58 9.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DJ-1_PfpI PF01965.24 EGE05111.1 - 4.7e-21 75.3 0.0 7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGE05111.1 - 0.00058 19.7 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I APH PF01636.23 EGE05113.1 - 1.8e-14 54.3 0.0 8.5e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE05113.1 - 0.001 18.0 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) APH PF01636.23 EGE05114.1 - 9.1e-11 42.1 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE05114.1 - 2.8e-05 23.8 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGE05114.1 - 0.00032 20.1 0.1 0.54 9.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain CBM_19 PF03427.13 EGE05114.1 - 0.025 14.5 0.2 0.081 12.9 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Fructosamin_kin PF03881.14 EGE05114.1 - 0.043 13.0 0.0 7.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.11 EGE05114.1 - 0.09 11.6 0.1 2.5 6.8 0.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) AA_permease_2 PF13520.6 EGE05115.1 - 5.6e-71 239.6 32.2 6.9e-71 239.3 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease DAP10 PF07213.11 EGE05115.1 - 0.03 14.3 1.6 0.72 9.8 0.4 2.6 2 0 0 2 2 2 0 DAP10 membrane protein adh_short PF00106.25 EGE05116.1 - 1.5e-40 138.8 0.0 1.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05116.1 - 7.4e-26 91.1 0.0 8.8e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05116.1 - 1.4e-08 34.9 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGE05116.1 - 0.00016 21.6 0.1 0.00031 20.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EGE05116.1 - 0.00028 21.1 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EGE05116.1 - 0.00038 20.0 0.0 0.0037 16.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EGE05116.1 - 0.052 13.1 0.1 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EGE05116.1 - 0.055 12.5 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 EGE05116.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CBFD_NFYB_HMF PF00808.23 EGE05117.1 - 7.3e-19 67.8 0.6 1.2e-18 67.1 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGE05117.1 - 4.7e-06 27.0 0.1 1.4e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EGE05117.1 - 0.029 14.4 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGE05117.1 - 0.078 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.10 EGE05117.1 - 0.3 11.2 4.4 0.17 12.0 2.2 1.6 2 0 0 2 2 2 0 YolD-like protein Actin PF00022.19 EGE05118.1 - 3.6e-21 75.2 0.0 1.1e-17 63.7 0.0 3.1 3 0 0 3 3 3 3 Actin Bystin PF05291.11 EGE05119.1 - 1.3e-127 425.1 0.0 1.7e-127 424.7 0.0 1.1 1 0 0 1 1 1 1 Bystin Amidase PF01425.21 EGE05121.1 - 7.8e-118 394.3 0.1 1.6e-117 393.3 0.1 1.4 1 1 0 1 1 1 1 Amidase Patatin PF01734.22 EGE05121.1 - 0.17 12.1 1.3 1.1 9.4 1.3 2.3 1 1 0 1 1 1 0 Patatin-like phospholipase DUF3347 PF11827.8 EGE05122.1 - 9.1 6.4 8.7 14 5.8 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) BTRD1 PF17660.1 EGE05123.1 - 4.8e-73 240.8 12.8 4e-15 55.4 0.1 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 bZIP_2 PF07716.15 EGE05124.1 - 3.4e-08 33.4 14.2 3.4e-08 33.4 14.2 2.6 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EGE05124.1 - 1.5e-06 28.2 17.8 7.8e-06 25.9 17.8 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EGE05124.1 - 0.012 16.1 12.0 0.012 16.1 12.0 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor FPP PF05911.11 EGE05124.1 - 0.018 13.3 6.1 0.027 12.7 6.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil SOGA PF11365.8 EGE05124.1 - 0.021 15.9 0.6 0.021 15.9 0.6 2.7 2 1 1 3 3 3 0 Protein SOGA DLIC PF05783.11 EGE05124.1 - 0.022 13.6 5.7 0.036 12.9 5.7 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Striatin PF08232.12 EGE05124.1 - 0.05 14.2 10.6 0.059 14.0 9.0 2.1 1 1 0 1 1 1 0 Striatin family APG6_N PF17675.1 EGE05124.1 - 0.3 11.6 13.1 0.52 10.8 13.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ATF7IP_BD PF16788.5 EGE05124.1 - 0.36 10.9 18.8 0.11 12.6 13.0 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain DUF3450 PF11932.8 EGE05124.1 - 0.72 9.1 7.0 1.2 8.4 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KIAA1430 PF13879.6 EGE05124.1 - 6.9 7.5 16.8 1.4 9.7 8.4 3.4 3 1 1 4 4 4 0 KIAA1430 homologue APH PF01636.23 EGE05126.1 - 7.5e-08 32.6 0.0 2.2e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE05126.1 - 0.00088 18.2 0.0 0.021 13.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.26 EGE05127.1 - 9.6e-15 54.7 0.0 1.9e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE05127.1 - 0.019 14.8 0.0 0.047 13.6 0.0 1.6 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MSV199 PF10553.9 EGE05127.1 - 0.13 12.6 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 MSV199 domain Metallophos PF00149.28 EGE05128.1 - 6.3e-10 39.9 0.2 1.7e-09 38.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EGE05128.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 EGE05129.1 - 4.6e-47 160.0 0.0 8.5e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGE05129.1 - 3.3e-35 120.7 0.1 8.6e-35 119.3 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_hydro_43 PF04616.14 EGE05130.1 - 6.1e-60 203.0 3.6 7e-60 202.8 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EGE05130.1 - 0.2 11.2 1.6 0.35 10.4 1.6 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain zf-C2H2 PF00096.26 EGE05131.1 - 0.0032 17.8 1.2 0.0071 16.7 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 EGE05131.1 - 0.006 16.9 0.3 0.011 16.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGE05131.1 - 0.015 15.6 2.3 0.025 14.9 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 EGE05131.1 - 0.079 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EGE05131.1 - 0.085 13.7 0.5 0.21 12.5 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Chorion_3 PF05387.11 EGE05131.1 - 7.6 6.1 9.5 11 5.5 9.5 1.2 1 0 0 1 1 1 0 Chorion family 3 DUF1691 PF07950.11 EGE05132.1 - 1.5e-41 141.5 5.8 3.5e-33 114.5 4.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Phage_holin_3_6 PF07332.11 EGE05132.1 - 1.3 9.1 4.8 0.56 10.3 0.3 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TRM PF02005.16 EGE05133.1 - 3.4e-109 365.5 0.0 2.6e-94 316.5 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 EGE05133.1 - 0.014 16.1 0.0 0.037 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05133.1 - 0.032 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EGE05133.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein DUF2067 PF09840.9 EGE05133.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) MTS PF05175.14 EGE05133.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FAS_I_H PF18314.1 EGE05134.1 - 9.7e-77 257.2 0.6 3.9e-76 255.2 0.0 2.2 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EGE05134.1 - 1.5e-75 253.0 0.2 3.6e-75 251.8 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EGE05134.1 - 6.3e-21 75.1 0.0 1.2e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EGE05134.1 - 8.6e-18 64.5 0.1 2e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EGE05134.1 - 2.8e-12 46.7 0.0 7.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EGE05134.1 - 6.7e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05134.1 - 0.003 17.2 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05134.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1729 PF08354.10 EGE05135.1 - 4.2e-162 539.0 0.0 6.5e-162 538.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EGE05135.1 - 3.8e-94 315.8 0.0 7.1e-91 305.0 0.0 3.7 5 0 0 5 5 5 2 Acyl transferase domain FAS_meander PF17951.1 EGE05135.1 - 6.2e-54 181.8 0.0 1.5e-53 180.5 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EGE05135.1 - 6.2e-39 132.4 0.1 2.6e-38 130.4 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain SAT PF16073.5 EGE05135.1 - 1.6e-37 129.5 0.9 4.8e-37 128.0 0.0 2.2 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EGE05135.1 - 1.2e-21 77.3 0.0 3.5e-21 75.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 EGE05135.1 - 0.041 13.9 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta Gamma-thionin PF00304.20 EGE05136.1 - 0.0039 17.4 7.4 0.005 17.1 7.4 1.2 1 0 0 1 1 1 1 Gamma-thionin family SLR1-BP PF07333.12 EGE05136.1 - 0.0045 17.4 3.4 0.0054 17.2 3.4 1.1 1 0 0 1 1 1 1 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Myticin-prepro PF10690.9 EGE05136.1 - 0.029 14.6 3.7 0.032 14.5 3.7 1.0 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Defensin_2 PF01097.18 EGE05136.1 - 0.93 9.5 10.8 1.5 8.8 10.8 1.4 1 1 0 1 1 1 0 Arthropod defensin His_Phos_2 PF00328.22 EGE05137.1 - 8.7e-107 357.8 0.0 1.1e-106 357.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EGE05137.1 - 9.7e-38 128.2 0.0 2e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EGE05137.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EGE05138.1 - 1.1e-81 273.8 0.1 1.6e-81 273.2 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGE05138.1 - 1.5e-12 47.8 28.2 0.00026 21.7 0.4 10.5 11 1 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05138.1 - 6.3e-12 45.6 0.3 0.0021 18.3 0.0 7.3 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE05138.1 - 1.2e-05 24.2 0.0 0.67 8.5 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Lgl_C PF08596.10 EGE05138.1 - 0.17 10.6 0.2 0.5 9.0 0.0 1.9 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal FeoB_associated PF12669.7 EGE05139.1 - 0.13 12.6 0.8 0.22 11.9 0.8 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF383 PF04063.14 EGE05140.1 - 3.4e-69 232.3 0.0 3.5e-68 229.1 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGE05140.1 - 7.5e-22 76.9 2.4 1.7e-21 75.8 1.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 EGE05140.1 - 0.00096 18.4 0.0 0.0021 17.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family C50 Rep-A_N PF04057.12 EGE05141.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain BRCA-2_OB1 PF09103.10 EGE05141.1 - 0.0069 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TPP1 PF10341.9 EGE05141.1 - 0.029 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD PAP_assoc PF03828.19 EGE05142.1 - 2.4e-07 30.8 0.0 5.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGE05142.1 - 0.045 14.0 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 EGE05143.1 - 1.6e-06 27.0 75.8 4e-05 22.4 71.6 3.5 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IBR PF01485.21 EGE05144.1 - 1.2e-10 41.4 44.2 6.1e-07 29.6 11.1 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain XPG_I_2 PF12813.7 EGE05145.1 - 4.6e-75 252.3 0.0 6.4e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc_N PF02739.16 EGE05145.1 - 0.033 14.1 0.0 0.35 10.8 0.0 2.5 3 0 0 3 3 3 0 5'-3' exonuclease, N-terminal resolvase-like domain Inositol_P PF00459.25 EGE05146.1 - 1.9e-68 230.9 0.0 2.4e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 EGE05147.1 - 1.9e-37 128.9 0.0 9.4e-36 123.4 0.0 2.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DAGK_cat PF00781.24 EGE05147.1 - 8.7e-12 44.8 0.0 2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lipase_3 PF01764.25 EGE05147.1 - 0.17 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Fcf1 PF04900.12 EGE05148.1 - 1.2e-36 125.0 1.4 1.3e-36 125.0 0.3 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EGE05148.1 - 2.4e-13 50.4 0.4 9.9e-13 48.4 0.1 1.9 2 0 0 2 2 2 1 PIN like domain Ras PF00071.22 EGE05150.1 - 8.5e-65 217.3 0.1 1e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE05150.1 - 3.3e-34 117.7 0.0 4.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE05150.1 - 1.7e-13 50.4 0.1 2.1e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE05150.1 - 8.4e-06 25.5 0.1 1.9e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGE05150.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGE05150.1 - 0.00063 19.7 0.1 0.62 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGE05150.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE05150.1 - 0.0049 16.4 0.0 0.026 14.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGE05150.1 - 0.0066 15.9 0.1 0.0081 15.6 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGE05150.1 - 0.15 12.3 0.1 0.46 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.10 EGE05151.1 - 6e-102 340.7 0.2 1.2e-101 339.8 0.1 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FANCF PF11107.8 EGE05151.1 - 0.013 14.8 0.2 0.036 13.3 0.1 2.0 2 1 0 2 2 2 0 Fanconi anemia group F protein (FANCF) FA_hydroxylase PF04116.13 EGE05152.1 - 7.8e-26 91.0 17.1 7.8e-26 91.0 17.1 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily AAA PF00004.29 EGE05153.1 - 2.3e-57 193.1 0.0 2.3e-40 138.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE05153.1 - 5.1e-13 48.6 0.6 4.8e-07 29.5 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGE05153.1 - 5.2e-08 33.4 1.9 0.094 13.1 0.4 4.0 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGE05153.1 - 7.4e-06 26.3 0.5 0.18 12.1 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGE05153.1 - 1.1e-05 25.4 0.5 0.0048 16.9 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 EGE05153.1 - 1.9e-05 24.6 0.0 0.008 16.0 0.0 3.0 2 1 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 EGE05153.1 - 0.00011 21.9 0.0 0.032 14.0 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EGE05153.1 - 0.00013 22.0 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 EGE05153.1 - 0.00014 21.2 0.3 0.0023 17.2 0.1 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 EGE05153.1 - 0.00014 22.2 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EGE05153.1 - 0.00016 21.3 0.3 6.2 6.3 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 EGE05153.1 - 0.00021 20.9 0.3 0.6 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 EGE05153.1 - 0.00025 21.3 0.0 0.63 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EGE05153.1 - 0.0005 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 EGE05153.1 - 0.00071 19.7 0.0 0.065 13.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_14 PF13173.6 EGE05153.1 - 0.00083 19.4 0.0 0.34 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGE05153.1 - 0.0014 18.4 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGE05153.1 - 0.0025 17.2 2.0 0.011 15.1 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGE05153.1 - 0.0034 16.6 0.0 2.3 7.3 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) NACHT PF05729.12 EGE05153.1 - 0.0076 16.2 0.4 5.7 6.8 0.1 2.9 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 EGE05153.1 - 0.023 14.4 0.5 6.1 6.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EGE05153.1 - 0.024 14.6 0.4 5.8 6.7 0.1 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea MCM PF00493.23 EGE05153.1 - 0.026 13.6 0.1 5.8 5.9 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_24 PF13479.6 EGE05153.1 - 0.033 13.9 0.2 5.6 6.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EGE05153.1 - 0.035 14.1 0.2 6.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_29 PF13555.6 EGE05153.1 - 0.13 12.1 0.2 1.1 9.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 EGE05153.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HNH_2 PF13391.6 EGE05154.1 - 1.6e-14 53.7 0.1 3.3e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease RRM_1 PF00076.22 EGE05155.1 - 7.7e-14 51.3 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE05155.1 - 0.00041 19.9 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE05155.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif PI3_PI4_kinase PF00454.27 EGE05156.1 - 9.2e-52 176.3 0.0 2e-51 175.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EGE05156.1 - 2.1e-32 111.0 0.2 1.3e-31 108.5 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FAT PF02259.23 EGE05156.1 - 2.8e-28 99.2 2.8 4.8e-28 98.4 0.6 2.3 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 EGE05156.1 - 1.9e-13 50.0 0.0 3.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 EGE05156.1 - 0.1 13.1 0.1 21 5.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE05156.1 - 0.17 12.7 0.4 15 6.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 EGE05157.1 - 8.4e-27 93.0 0.1 1.1e-26 92.7 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGE05157.1 - 9.3e-22 77.3 0.0 1.2e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGE05157.1 - 0.0094 16.0 0.2 0.027 14.5 0.2 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EGE05157.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EGE05157.1 - 0.053 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 XOO_2897-deam PF14440.6 EGE05157.1 - 0.081 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase NADH-u_ox-rdase PF10785.9 EGE05158.1 - 5.4e-27 94.3 0.4 1.5e-26 92.9 0.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EGE05158.1 - 2e-26 91.8 0.1 2.9e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 EGE05159.1 - 2.4e-31 107.5 0.1 5e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Peptidase_U32 PF01136.19 EGE05159.1 - 0.19 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family U32 RCC1 PF00415.18 EGE05160.1 - 7.9e-60 199.3 13.0 1.7e-10 41.4 0.3 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGE05160.1 - 3.1e-40 135.2 33.6 5.3e-08 32.5 1.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat PCM1_C PF15717.5 EGE05160.1 - 0.1 11.3 0.7 0.14 10.8 0.7 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus RibD_C PF01872.17 EGE05161.1 - 7.4e-29 101.0 0.0 1.4e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.14 EGE05162.1 - 9.3e-222 737.9 0.0 1.2e-221 737.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 EGE05162.1 - 1.3 9.9 28.7 0.23 12.3 18.3 2.6 2 0 0 2 2 2 0 Nucleoporin FG repeat region COX16 PF14138.6 EGE05163.1 - 1.8e-25 89.2 0.5 2e-25 89.1 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RAP80_UIM PF18282.1 EGE05163.1 - 0.13 12.0 0.2 0.18 11.6 0.2 1.4 1 1 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Y_phosphatase PF00102.27 EGE05164.1 - 2.2e-65 220.5 0.0 3.6e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGE05164.1 - 0.079 12.8 2.3 0.17 11.7 2.3 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CCAP PF11105.8 EGE05164.1 - 0.21 11.6 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a F-box PF00646.33 EGE05165.1 - 0.0013 18.6 2.2 0.0026 17.6 2.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 EGE05165.1 - 0.0024 17.8 0.2 0.005 16.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.7 EGE05165.1 - 0.26 11.2 2.5 0.69 9.8 2.5 1.7 1 0 0 1 1 1 0 F-box-like FGGY_C PF02782.16 EGE05168.1 - 1.6e-50 171.6 0.2 2.5e-50 171.0 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGE05168.1 - 9.2e-23 81.1 0.0 1e-21 77.7 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EGE05168.1 - 0.066 12.7 0.1 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.7 EGE05169.1 - 0.0068 16.3 0.1 0.025 14.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 EGE05171.1 - 1.7e-43 148.2 0.0 2.8e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE05171.1 - 4.4e-14 52.0 0.0 1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGE05171.1 - 9.2e-08 32.4 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGE05171.1 - 1.6e-07 31.4 0.0 3.9e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGE05171.1 - 2e-06 28.3 0.0 0.00012 22.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EGE05171.1 - 2.8e-05 24.4 0.2 0.0064 16.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGE05171.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGE05171.1 - 0.00099 19.7 0.0 0.02 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGE05171.1 - 0.001 18.4 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGE05171.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGE05171.1 - 0.0029 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGE05171.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGE05171.1 - 0.0081 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EGE05171.1 - 0.0091 15.4 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 EGE05171.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGE05171.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EGE05171.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EGE05171.1 - 0.023 14.4 0.0 0.1 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGE05171.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region HR1 PF02185.16 EGE05171.1 - 0.037 14.1 0.7 0.095 12.8 0.7 1.7 1 0 0 1 1 1 0 Hr1 repeat RNA_helicase PF00910.22 EGE05171.1 - 0.037 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EGE05171.1 - 0.037 13.5 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EGE05171.1 - 0.038 14.0 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGE05171.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGE05171.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGE05171.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EGE05171.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Prot_ATP_ID_OB PF16450.5 EGE05171.1 - 0.12 12.3 1.2 0.44 10.5 1.2 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Na_Ca_ex PF01699.24 EGE05172.1 - 2.4e-21 76.3 36.9 1.7e-15 57.3 13.4 3.5 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EGE05172.1 - 6.7e-15 55.5 10.9 6.7e-15 55.5 10.9 4.4 5 0 0 5 5 5 1 Inner membrane component domain Peptidase_S10 PF00450.22 EGE05173.1 - 6.4e-88 296.0 0.5 9.3e-88 295.4 0.5 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Choline_transpo PF04515.12 EGE05174.1 - 2.2e-81 273.6 22.6 2.2e-81 273.6 22.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter tRNA-synt_1g PF09334.11 EGE05176.1 - 1.3e-141 471.9 0.0 1.7e-141 471.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGE05176.1 - 0.0003 19.2 0.6 0.0043 15.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) HNH_2 PF13391.6 EGE05178.1 - 3.3e-19 68.8 0.0 8.5e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease Alk_phosphatase PF00245.20 EGE05178.1 - 0.19 10.7 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Vps8 PF12816.7 EGE05180.1 - 2e-58 197.2 2.3 1.1e-57 194.7 0.2 2.5 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGE05180.1 - 4.5e-09 36.3 9.0 0.00019 21.3 0.5 5.0 5 1 1 6 6 6 2 Region in Clathrin and VPS Pox_D3 PF04580.13 EGE05180.1 - 0.026 14.1 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-C3H2C3 PF17122.5 EGE05180.1 - 0.082 13.0 0.1 0.082 13.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger zf-ANAPC11 PF12861.7 EGE05180.1 - 0.16 12.1 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Interferon PF00143.19 EGE05180.1 - 0.74 10.0 7.0 0.075 13.2 0.8 2.4 3 0 0 3 3 3 0 Interferon alpha/beta domain Glyco_hydro_16 PF00722.21 EGE05182.1 - 3.4e-08 33.1 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.12 EGE05183.1 - 4.9e-12 45.5 0.0 0.00017 20.6 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF2721 PF11026.8 EGE05183.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) GNAT_acetyltr_2 PF13718.6 EGE05184.1 - 3.2e-98 327.6 0.0 5.7e-98 326.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGE05184.1 - 4.6e-76 255.6 0.2 1.5e-72 244.1 0.1 2.4 1 1 1 2 2 2 2 Possible tRNA binding domain Helicase_RecD PF05127.14 EGE05184.1 - 3.8e-65 219.1 0.0 1.2e-64 217.4 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EGE05184.1 - 3.3e-35 119.9 0.0 8.9e-35 118.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EGE05184.1 - 0.00033 20.4 0.0 0.069 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGE05184.1 - 0.024 14.9 0.0 0.43 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 EGE05184.1 - 0.031 14.5 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.20 EGE05185.1 - 1.3e-28 99.0 0.0 2.1e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGE05185.1 - 2.6e-06 27.8 0.0 0.0028 18.1 0.1 2.8 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGE05185.1 - 4e-05 23.1 0.0 0.00022 20.7 0.0 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGE05185.1 - 0.0021 18.3 0.0 0.56 10.6 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 EGE05185.1 - 0.0046 16.9 0.0 0.051 13.5 0.0 2.5 3 0 0 3 3 3 1 AhpC/TSA family TraF PF13728.6 EGE05185.1 - 0.047 13.5 0.0 0.047 13.5 0.0 4.3 3 1 1 4 4 4 0 F plasmid transfer operon protein CCDC53 PF10152.9 EGE05185.1 - 6.4 7.2 17.0 1.2 9.6 1.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ATP-synt PF00231.19 EGE05188.1 - 5.6e-77 259.2 3.1 6.8e-77 258.9 3.1 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I PF01028.20 EGE05189.1 - 2.1e-98 328.2 2.5 2.1e-98 328.2 2.5 2.8 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGE05189.1 - 1.9e-96 321.6 1.7 1.9e-96 321.6 1.7 3.9 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGE05189.1 - 8.2e-33 112.2 1.0 3.5e-32 110.1 1.0 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Epimerase PF01370.21 EGE05190.1 - 1.5e-07 31.1 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGE05190.1 - 0.00016 20.9 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Rab15_effector PF15208.6 EGE05192.1 - 0.043 13.1 0.1 0.054 12.8 0.1 1.1 1 0 0 1 1 1 0 Rab15 effector Vta1 PF04652.16 EGE05194.1 - 1.5e-55 187.1 6.8 1.5e-55 187.1 6.8 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGE05194.1 - 1.9e-18 65.9 0.2 5.8e-18 64.3 0.2 1.9 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C2 PF00648.21 EGE05195.1 - 6.6e-31 107.4 0.0 1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGE05195.1 - 3.4e-08 33.9 0.0 1.3e-05 25.4 0.0 3.2 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 EGE05195.1 - 0.044 13.8 0.5 0.08 13.0 0.5 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 EGE05196.1 - 5.2e-58 193.0 2.0 5.4e-23 80.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3147 PF11345.8 EGE05196.1 - 0.058 13.8 1.6 0.086 13.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) PrcB_C PF14343.6 EGE05196.1 - 0.09 12.9 0.3 21 5.4 0.0 3.4 3 0 0 3 3 3 0 PrcB C-terminal SNase PF00565.17 EGE05197.1 - 1.7e-24 86.3 0.0 2.5e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.22 EGE05198.1 - 5.5e-36 123.9 0.0 5.8e-19 68.7 0.0 2.1 1 1 1 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EGE05198.1 - 2.5e-16 59.4 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EGE05198.1 - 3.2e-13 50.3 0.0 6.6e-12 46.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE05198.1 - 7.3e-05 23.3 0.0 0.00031 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE05198.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EGE05198.1 - 0.092 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EGE05198.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_primase_lrg PF04104.14 EGE05199.1 - 5.9e-85 284.9 0.0 8.5e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Phage_head_chap PF11113.8 EGE05199.1 - 0.13 12.4 0.1 0.49 10.5 0.1 2.0 1 0 0 1 1 1 0 Head assembly gene product Sec23_trunk PF04811.15 EGE05200.1 - 7e-78 261.5 0.0 1e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGE05200.1 - 8.5e-29 100.1 0.0 1.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGE05200.1 - 5.5e-25 87.2 0.2 1.4e-24 85.8 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGE05200.1 - 1.4e-14 53.8 4.5 2.6e-14 53.0 4.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGE05200.1 - 4.5e-11 42.5 0.0 1.2e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGE05200.1 - 0.15 11.4 1.4 0.22 10.9 0.3 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EGE05201.1 - 2.5e-23 81.7 0.3 3.9e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGE05201.1 - 6.9e-15 55.3 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NPR3 PF03666.13 EGE05202.1 - 3.8 6.2 5.5 4.3 6.0 5.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_transf_41 PF13844.6 EGE05203.1 - 3.7e-102 342.2 0.1 9.5e-52 176.0 0.0 3.3 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_2 PF07719.17 EGE05203.1 - 3.3e-15 54.9 10.8 0.001 19.0 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGE05203.1 - 4.3e-15 55.1 12.7 0.0014 18.3 0.5 6.3 3 2 3 6 6 6 4 TPR repeat TPR_1 PF00515.28 EGE05203.1 - 3.3e-14 52.0 9.4 0.00091 19.0 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05203.1 - 1e-08 34.7 9.2 0.036 14.3 0.1 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE05203.1 - 4.9e-07 30.0 5.1 0.041 14.7 0.0 5.6 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGE05203.1 - 1.3e-06 28.4 5.5 3.3 8.3 0.0 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE05203.1 - 1.7e-06 28.6 9.2 0.21 12.2 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05203.1 - 2.8e-06 27.5 8.8 0.19 12.0 0.2 5.4 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGE05203.1 - 2.9e-06 27.0 14.4 0.44 10.5 0.7 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE05203.1 - 4.2e-05 23.7 0.4 0.00054 20.1 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGE05203.1 - 4.9e-05 23.8 8.0 0.081 13.4 0.2 3.8 3 2 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 EGE05203.1 - 0.00047 20.6 0.7 0.23 11.9 0.0 2.8 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 EGE05203.1 - 0.0034 17.3 7.2 0.68 10.1 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGE05203.1 - 0.037 13.2 2.8 2.5 7.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGE05203.1 - 0.68 10.1 5.5 1.2 9.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3807 PF12720.7 EGE05204.1 - 0.14 12.4 10.3 0.22 11.8 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Coilin_N PF15862.5 EGE05204.1 - 0.33 10.7 7.6 0.49 10.2 7.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus Sec6 PF06046.13 EGE05204.1 - 1 7.7 5.2 1.3 7.3 5.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 CDC45 PF02724.14 EGE05204.1 - 1.4 7.1 8.8 1.6 6.9 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SelK_SelG PF10961.8 EGE05204.1 - 2.5 8.8 7.8 4.5 7.9 6.0 2.2 2 1 0 2 2 2 0 Selenoprotein SelK_SelG Connexin PF00029.19 EGE05204.1 - 3.2 7.4 4.1 4.8 6.9 4.1 1.2 1 0 0 1 1 1 0 Connexin DUF4710 PF15828.5 EGE05204.1 - 3.8 7.7 13.4 8.1 6.7 13.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) AP3D1 PF06375.11 EGE05204.1 - 4.3 7.5 14.4 7.3 6.8 14.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ferlin_C PF16165.5 EGE05204.1 - 5 7.0 7.2 8 6.4 7.2 1.4 1 0 0 1 1 1 0 Ferlin C-terminus Myb_DNA-binding PF00249.31 EGE05206.1 - 2.8e-26 91.4 1.8 9.7e-15 54.5 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE05206.1 - 1.8e-18 66.5 6.4 6e-14 52.0 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_23 PF13384.6 EGE05206.1 - 0.058 13.2 0.2 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF2774 PF11242.8 EGE05206.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) RAB3GAP2_N PF14655.6 EGE05206.1 - 0.22 10.8 1.3 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Myb_DNA-bind_4 PF13837.6 EGE05206.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.6 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ABC_tran PF00005.27 EGE05208.1 - 2.8e-48 163.9 0.0 3.1e-29 102.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EGE05208.1 - 5.4e-31 108.2 20.4 4.8e-21 75.6 6.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGE05208.1 - 1.7e-09 37.5 4.2 0.00061 19.3 0.9 4.8 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE05208.1 - 1.8e-06 27.6 0.7 0.042 13.6 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGE05208.1 - 8.4e-05 23.2 0.7 0.2 12.1 0.2 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGE05208.1 - 0.00014 22.3 0.8 0.17 12.3 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EGE05208.1 - 0.00021 21.4 4.7 0.007 16.5 0.4 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 EGE05208.1 - 0.00038 20.7 2.1 0.4 10.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_21 PF13304.6 EGE05208.1 - 0.00042 20.2 5.6 0.83 9.4 1.1 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGE05208.1 - 0.0019 18.1 0.1 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EGE05208.1 - 0.0021 17.2 0.1 0.6 9.1 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EGE05208.1 - 0.0085 16.2 0.2 0.29 11.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EGE05208.1 - 0.013 15.1 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE05208.1 - 0.022 14.5 0.3 0.16 11.7 0.0 2.6 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 EGE05208.1 - 0.023 13.9 0.1 7.8 5.6 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain AAA_10 PF12846.7 EGE05208.1 - 0.033 13.1 0.5 2.5 6.9 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.6 EGE05208.1 - 0.045 13.9 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGE05208.1 - 0.049 13.9 0.5 31 4.9 0.0 3.8 4 0 0 4 4 3 0 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 EGE05208.1 - 0.063 12.3 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 EGE05208.1 - 0.069 12.9 0.5 16 5.2 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGE05208.1 - 0.086 13.4 0.7 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGE05208.1 - 0.1 11.9 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EGE05208.1 - 0.11 12.1 0.2 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EGE05208.1 - 0.17 11.3 0.0 19 4.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein CbiA PF01656.23 EGE05208.1 - 0.2 11.7 0.0 0.52 10.4 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EGE05208.1 - 0.38 10.6 4.0 24 4.8 0.0 3.7 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.14 EGE05208.1 - 5.1 7.1 6.0 38 4.3 0.1 4.4 5 1 1 6 6 6 0 AAA domain (dynein-related subfamily) Cu-oxidase_3 PF07732.15 EGE05209.1 - 9.3e-12 45.0 0.5 4.9e-08 33.0 0.2 2.6 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE05209.1 - 5.2e-10 39.2 0.1 0.0033 17.2 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE05209.1 - 0.0056 16.8 0.0 0.0089 16.2 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Copper-bind PF00127.20 EGE05209.1 - 0.18 12.3 0.0 0.52 10.8 0.0 1.8 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family NCBP3 PF10309.9 EGE05210.1 - 1e-23 82.9 0.0 2.1e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Ribosomal_L29e PF01779.17 EGE05211.1 - 5.9e-22 77.7 12.6 9.8e-22 77.0 12.6 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.16 EGE05212.1 - 2.5e-15 56.1 0.0 3.9e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.16 EGE05213.1 - 0.013 15.6 10.4 0.013 15.6 10.4 1.7 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EGE05213.1 - 2.7 8.1 19.1 0.56 10.4 2.5 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 EGE05213.1 - 9.6 6.1 9.9 0.85 9.4 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) APH PF01636.23 EGE05214.1 - 4.8e-43 147.8 0.0 7.9e-43 147.1 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE05214.1 - 1.3e-05 24.7 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EGE05214.1 - 0.0014 18.0 0.1 0.0033 16.8 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EGE05214.1 - 0.0047 16.2 0.0 0.07 12.3 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 EGE05214.1 - 0.033 13.8 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF4142 PF13628.6 EGE05214.1 - 0.14 12.4 0.3 0.25 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Securin PF04856.13 EGE05215.1 - 0.01 15.8 3.7 0.012 15.6 3.7 1.0 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor CDC45 PF02724.14 EGE05215.1 - 0.17 10.1 9.4 0.16 10.2 9.4 1.0 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 EGE05215.1 - 0.39 10.6 3.1 0.39 10.6 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Tim54 PF11711.8 EGE05215.1 - 0.5 9.1 9.3 0.56 8.9 9.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 EGE05215.1 - 0.51 9.3 5.1 0.48 9.3 5.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 EGE05215.1 - 0.64 10.1 2.7 0.66 10.1 2.7 1.0 1 0 0 1 1 1 0 DDHD domain MAP17 PF15807.5 EGE05215.1 - 0.7 10.1 7.0 0.76 10.0 7.0 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Myc_N PF01056.18 EGE05215.1 - 0.76 9.6 8.9 0.85 9.5 8.9 1.0 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EGE05215.1 - 0.76 9.0 10.2 0.81 9.0 10.2 1.0 1 0 0 1 1 1 0 NOA36 protein RNA_polI_A34 PF08208.11 EGE05215.1 - 1 9.4 12.9 1.2 9.2 12.9 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.6 EGE05215.1 - 1.4 8.6 10.6 2.2 7.9 10.6 1.3 1 0 0 1 1 1 0 FAM176 family VIR_N PF15912.5 EGE05215.1 - 1.7 8.2 8.0 1.8 8.1 8.0 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal PBP1_TM PF14812.6 EGE05215.1 - 1.7 9.1 12.5 2.1 8.8 12.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 EGE05215.1 - 1.8 7.7 3.5 1.8 7.7 3.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 EGE05215.1 - 2.1 7.5 9.5 2.1 7.5 9.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-N PF05238.13 EGE05215.1 - 2.2 7.5 8.3 2.6 7.3 8.3 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 EGE05215.1 - 2.5 6.8 7.7 2.6 6.7 7.7 1.0 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 EGE05215.1 - 2.5 7.7 21.8 2.8 7.5 21.8 1.0 1 0 0 1 1 1 0 DDRGK domain DNA_pol_phi PF04931.13 EGE05215.1 - 3 5.8 15.0 3.2 5.7 15.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Porph_ging PF09697.10 EGE05215.1 - 3.3 8.3 6.2 4.2 8.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) DUF4746 PF15928.5 EGE05215.1 - 5.8 6.2 14.6 6.5 6.1 14.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFB6 PF17110.5 EGE05215.1 - 6.9 6.4 8.1 8 6.2 8.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4820 PF16091.5 EGE05215.1 - 7.5 5.8 10.0 8.3 5.7 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sporozoite_P67 PF05642.11 EGE05215.1 - 8.5 4.3 7.9 9.4 4.2 7.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP_sp32 PF07222.12 EGE05215.1 - 9.4 5.6 12.4 11 5.4 12.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-C2H2 PF00096.26 EGE05216.1 - 5.6e-10 39.1 15.6 0.0011 19.3 2.4 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE05216.1 - 3.4e-05 24.3 11.8 0.011 16.5 1.9 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE05216.1 - 4.3e-05 23.7 10.9 0.33 11.4 0.2 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.12 EGE05216.1 - 0.016 15.5 4.9 0.11 12.8 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EGE05216.1 - 0.058 13.2 0.7 0.058 13.2 0.7 4.0 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Mfp-3 PF04202.13 EGE05216.1 - 0.15 12.4 0.0 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 Foot protein 3 PQ-loop PF04193.14 EGE05217.1 - 1.9e-30 104.4 11.3 7.3e-18 64.1 1.5 2.4 2 0 0 2 2 2 2 PQ loop repeat SPATA9 PF15824.5 EGE05217.1 - 0.45 9.8 1.0 0.8 8.9 0.2 1.7 1 1 0 2 2 2 0 Spermatogenesis-associated protein 9 Phos_pyr_kin PF08543.12 EGE05218.1 - 1.4e-11 44.2 0.0 3e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGE05218.1 - 8.1e-08 31.9 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase BON PF04972.17 EGE05218.1 - 0.069 13.5 1.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 BON domain dUTPase PF00692.19 EGE05219.1 - 8.6e-28 96.6 0.0 1.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 dUTPase ADIP PF11559.8 EGE05220.1 - 3.3e-39 134.4 12.4 3.3e-39 134.4 12.4 2.3 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EGE05220.1 - 0.0048 16.4 10.0 0.0048 16.4 10.0 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF3450 PF11932.8 EGE05220.1 - 0.036 13.4 9.8 0.13 11.6 9.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EGE05220.1 - 0.34 10.7 9.9 0.25 11.2 6.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TTRAP PF14203.6 EGE05220.1 - 0.35 10.9 2.7 0.49 10.4 0.3 2.4 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein RasGAP_C PF03836.15 EGE05220.1 - 0.39 10.9 9.7 4.4 7.4 2.0 2.8 1 1 1 2 2 2 0 RasGAP C-terminus HAUS6_N PF14661.6 EGE05220.1 - 0.88 9.1 5.4 2.3 7.7 5.4 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus KxDL PF10241.9 EGE05220.1 - 1 9.7 10.6 0.17 12.2 5.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF641 PF04859.12 EGE05220.1 - 1.1 9.6 12.0 1.2e+02 3.1 8.7 3.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TRAF_BIRC3_bd PF16673.5 EGE05220.1 - 2.8 7.8 7.1 0.43 10.4 2.4 2.2 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Fib_alpha PF08702.10 EGE05220.1 - 4.4 7.5 12.4 1.3 9.2 7.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PKcGMP_CC PF16808.5 EGE05220.1 - 5.8 6.9 7.4 48 3.9 0.6 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAM_2 PF07647.17 EGE05221.1 - 0.0019 18.3 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MerR-DNA-bind PF09278.11 EGE05221.1 - 0.29 11.7 2.3 1.6 9.3 0.6 2.8 3 0 0 3 3 3 0 MerR, DNA binding Pyr_redox_2 PF07992.14 EGE05222.1 - 8.2e-53 179.5 0.4 1e-52 179.2 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE05222.1 - 7.3e-18 64.9 0.6 1.2e-14 54.6 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EGE05222.1 - 3.3e-16 59.0 0.0 7.2e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 EGE05222.1 - 3.9e-08 32.9 0.3 8.9e-06 25.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EGE05222.1 - 2.1e-06 28.2 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.6 EGE05222.1 - 3.6e-06 27.1 0.2 0.13 12.2 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGE05222.1 - 6.2e-06 25.6 0.0 0.092 11.9 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.6 EGE05222.1 - 0.00015 21.6 0.0 0.00041 20.2 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.11 EGE05222.1 - 0.0014 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 EGE05222.1 - 0.0033 17.8 0.3 0.43 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.14 EGE05222.1 - 0.0069 15.1 0.3 2.5 6.7 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein FIST PF08495.10 EGE05222.1 - 0.013 15.6 0.1 0.061 13.3 0.0 2.1 2 0 0 2 2 2 0 FIST N domain Amino_oxidase PF01593.24 EGE05222.1 - 0.039 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EGE05222.1 - 0.098 12.9 0.2 6.9 7.0 0.2 2.6 2 0 0 2 2 2 0 TrkA-N domain IDEAL PF08858.10 EGE05223.1 - 0.53 10.1 2.6 1.2 8.9 2.6 1.6 1 0 0 1 1 1 0 IDEAL domain Arrestin_N PF00339.29 EGE05224.1 - 1e-11 45.1 0.7 8.6e-07 29.1 0.0 4.0 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EGE05224.1 - 0.013 14.9 0.0 0.048 13.1 0.0 1.9 3 0 0 3 3 3 0 Bul1 C terminus DUF908 PF06012.12 EGE05225.1 - 2 7.7 4.1 2.1 7.7 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SPX PF03105.19 EGE05225.1 - 6.7 6.5 8.3 7.8 6.3 8.3 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 EGE05225.1 - 8.3 4.8 5.0 7.5 5.0 5.0 1.1 1 0 0 1 1 1 0 Macoilin family HD PF01966.22 EGE05226.1 - 0.00074 19.7 0.1 0.0063 16.7 0.0 2.4 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 EGE05226.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase RMI1_C PF16099.5 EGE05226.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold PPR_1 PF12854.7 EGE05226.1 - 0.26 11.0 0.6 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 PPR repeat DPM2 PF07297.12 EGE05228.1 - 2.1e-31 108.0 1.4 2.4e-31 107.8 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGE05228.1 - 1.5e-06 28.2 0.4 1.7e-06 28.0 0.4 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EGE05228.1 - 0.01 15.9 2.2 0.023 14.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.6 EGE05228.1 - 0.02 14.7 2.0 0.038 13.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LapA_dom PF06305.11 EGE05228.1 - 0.046 13.5 0.1 0.046 13.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 EGE05228.1 - 0.084 12.9 3.0 0.11 12.5 3.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 EGE05228.1 - 10 6.5 8.8 3.1 8.2 2.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) MA3 PF02847.17 EGE05229.1 - 1.6e-26 92.5 0.1 4e-26 91.2 0.1 1.7 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EGE05229.1 - 5.2e-12 45.9 0.1 1.1e-11 44.9 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain DUF3915 PF13054.6 EGE05230.1 - 0.0037 17.2 5.7 0.0037 17.2 5.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) RRM_1 PF00076.22 EGE05231.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L7Ae PF01248.26 EGE05237.1 - 1.6e-24 85.5 0.0 1.8e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Formyl_trans_N PF00551.19 EGE05238.1 - 1.5e-38 132.3 0.0 1.8e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase SPA PF08616.10 EGE05239.1 - 5e-37 126.3 0.0 8.1e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGE05239.1 - 3.9e-33 114.8 0.3 7.5e-33 113.8 0.3 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGE05239.1 - 1.4e-07 30.6 0.0 0.046 12.4 0.0 3.7 2 1 1 3 3 3 3 Transport protein Avl9 EF-hand_6 PF13405.6 EGE05240.1 - 3.3e-14 51.5 0.9 6.7e-06 25.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGE05240.1 - 1.6e-12 46.0 1.3 2.1e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGE05240.1 - 4.8e-10 39.7 0.1 0.00066 20.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGE05240.1 - 4.3e-08 32.3 3.0 0.0041 16.6 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGE05240.1 - 1.7e-06 27.8 0.2 0.036 13.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGE05240.1 - 0.0025 18.1 0.0 2.7 8.4 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain RabGAP-TBC PF00566.18 EGE05241.1 - 2.4e-31 109.1 0.0 1.3e-30 106.6 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF1455 PF07306.11 EGE05241.1 - 0.24 11.4 1.9 0.58 10.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) SET PF00856.28 EGE05244.1 - 5.3e-09 36.7 0.0 1.2e-07 32.2 0.0 2.7 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGE05244.1 - 0.057 13.5 6.0 0.16 12.0 6.0 1.9 1 0 0 1 1 1 0 MYND finger WD40 PF00400.32 EGE05245.1 - 6.3e-23 80.6 14.8 3.3e-06 27.7 0.3 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05245.1 - 0.00024 21.3 0.0 0.017 15.4 0.0 3.5 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ECH_1 PF00378.20 EGE05246.1 - 0.26 10.6 0.9 0.49 9.6 0.9 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase FAM76 PF16046.5 EGE05246.1 - 0.32 10.3 5.0 0.65 9.3 5.0 1.4 1 0 0 1 1 1 0 FAM76 protein DUF3484 PF11983.8 EGE05246.1 - 9 7.5 0.0 9 7.5 0.0 3.4 4 1 0 4 4 4 0 Membrane-attachment and polymerisation-promoting switch Glucosamine_iso PF01182.20 EGE05247.1 - 2.4e-68 230.4 0.0 2.7e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TPR_2 PF07719.17 EGE05250.1 - 1.6e-09 37.2 8.3 0.037 14.1 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05250.1 - 2e-06 28.0 6.1 0.024 14.9 3.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box PF00646.33 EGE05250.1 - 2.8e-06 27.0 0.0 8.7e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 EGE05250.1 - 1.5e-05 24.6 5.9 0.2 11.6 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGE05250.1 - 0.0003 21.3 8.3 0.12 13.1 3.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat F-box-like PF12937.7 EGE05250.1 - 0.0032 17.3 0.0 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 EGE05250.1 - 0.0058 16.7 2.4 1 9.5 0.1 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGE05250.1 - 0.027 14.5 7.6 2.5 8.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGE05250.1 - 0.034 13.8 1.3 0.81 9.4 0.0 3.2 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 EGE05250.1 - 0.12 13.2 11.2 2.4 9.2 1.0 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE05250.1 - 0.14 12.6 6.9 0.68 10.5 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGE05250.1 - 0.17 11.8 5.4 3.6 7.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05250.1 - 0.96 9.8 5.5 23 5.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGE05250.1 - 1.2 9.2 4.6 3.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGE05250.1 - 3.4 7.9 5.9 2.8 8.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat IDO PF01231.18 EGE05251.1 - 3.9e-34 118.2 0.0 9.3e-34 116.9 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Glyco_hydro_16 PF00722.21 EGE05252.1 - 2.4e-10 40.1 0.1 3.9e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Goodbye PF17109.5 EGE05253.1 - 9.4e-37 126.2 0.2 3.5e-36 124.3 0.0 2.1 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_2 PF07719.17 EGE05253.1 - 4.1e-10 39.0 10.0 0.0085 16.1 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05253.1 - 6.1e-09 36.1 2.8 0.0016 18.7 0.0 4.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE05253.1 - 1.8e-08 33.8 4.1 0.0035 17.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05253.1 - 3.8e-07 29.8 0.5 0.1 12.9 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE05253.1 - 9.8e-07 28.4 5.5 0.75 10.0 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 EGE05253.1 - 0.00089 19.7 0.0 0.015 15.7 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EGE05253.1 - 0.0042 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 EGE05253.1 - 0.0046 17.4 0.0 1.8 9.1 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGE05253.1 - 0.023 14.6 0.6 8.5 6.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2075 PF09848.9 EGE05253.1 - 0.035 13.4 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_14 PF13428.6 EGE05253.1 - 0.062 14.2 0.2 41 5.4 0.0 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Msap1 PF17077.5 EGE05253.1 - 0.085 12.0 0.9 0.14 11.4 0.2 1.6 2 0 0 2 2 2 0 Mitotic spindle associated protein SHE1 TPR_6 PF13174.6 EGE05253.1 - 0.097 13.3 16.0 0.43 11.3 0.4 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EGE05253.1 - 0.11 12.2 1.3 0.24 11.1 0.2 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 EspB PF05802.11 EGE05253.1 - 0.39 10.7 3.7 0.7 9.8 3.7 1.4 1 0 0 1 1 1 0 Enterobacterial EspB protein CLTH PF10607.9 EGE05254.1 - 6e-34 117.1 0.0 1.1e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EGE05254.1 - 2.2e-24 85.9 0.2 3.9e-24 85.1 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EGE05254.1 - 0.0039 17.1 0.5 0.0092 15.9 0.1 1.9 2 0 0 2 2 2 1 LisH Serglycin PF04360.12 EGE05254.1 - 6.3 6.7 9.9 0.52 10.2 2.6 2.5 2 0 0 2 2 2 0 Serglycin INO80_Ies4 PF08193.11 EGE05255.1 - 1e-69 235.2 32.7 1e-69 235.2 32.7 1.8 1 1 1 2 2 2 1 INO80 complex subunit Ies4 SpoIIP PF07454.11 EGE05255.1 - 0.6 9.5 6.4 1 8.8 6.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FGF-BP1 PF06473.12 EGE05255.1 - 0.95 9.2 13.0 0.15 11.9 7.7 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) CPSF100_C PF13299.6 EGE05255.1 - 1.6 8.9 10.4 0.41 10.8 5.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MCM_bind PF09739.9 EGE05255.1 - 1.7 7.0 4.1 2.5 6.4 4.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF913 PF06025.12 EGE05255.1 - 6 5.7 10.2 0.54 9.2 3.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DnaJ PF00226.31 EGE05256.1 - 1.7e-12 47.2 0.0 4.7e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain HXXEE PF13787.6 EGE05256.1 - 0.48 11.2 4.3 0.2 12.4 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif Myb_DNA-bind_7 PF15963.5 EGE05256.1 - 1.2 9.1 5.0 9.7 6.2 3.6 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Ribosomal_60s PF00428.19 EGE05256.1 - 4.8 7.8 7.1 10 6.8 7.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RPA43_OB PF17875.1 EGE05257.1 - 1.6e-40 138.6 0.1 1.6e-40 138.6 0.1 3.5 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I Rab5ip PF07019.12 EGE05258.1 - 2.4e-22 79.3 3.4 3.1e-22 79.0 3.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 EGE05258.1 - 0.5 10.8 4.9 0.69 10.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5084) DSBA PF01323.20 EGE05259.1 - 2.7e-32 112.1 0.0 3.4e-32 111.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EGE05259.1 - 0.00022 21.4 0.4 0.003 17.8 0.0 2.1 1 1 0 2 2 2 1 Thioredoxin MFS_1 PF07690.16 EGE05260.1 - 1.1e-30 106.8 61.8 4.3e-27 95.0 53.6 3.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGE05260.1 - 1.3e-12 46.9 13.8 2.7e-12 45.9 13.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sulfate_transp PF00916.20 EGE05261.1 - 1.5e-104 349.8 20.9 2e-104 349.4 20.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGE05261.1 - 4.7e-07 29.4 0.0 9.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain DnaJ_C PF01556.18 EGE05263.1 - 5.8e-39 133.5 0.0 7.7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGE05263.1 - 5.3e-25 87.3 2.4 8.7e-25 86.6 2.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGE05263.1 - 9.3e-15 54.8 18.6 1.6e-14 54.0 18.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EGE05263.1 - 1.2 9.1 10.0 1.5 8.8 2.3 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA URO-D PF01208.17 EGE05264.1 - 1.1e-130 435.8 0.0 1.2e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Nod1 PF17114.5 EGE05264.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 WD40 PF00400.32 EGE05265.1 - 0.0072 17.2 3.3 0.21 12.5 0.8 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribosomal_L10 PF00466.20 EGE05266.1 - 7.6e-24 83.8 0.1 2.1e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGE05266.1 - 1.2e-20 73.3 0.1 2.2e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EGE05266.1 - 1e-11 45.2 1.2 2.2e-11 44.2 0.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Atrophin-1 PF03154.15 EGE05267.1 - 0.0039 15.6 13.9 0.0048 15.3 10.1 1.9 2 0 0 2 2 2 2 Atrophin-1 family DUF3915 PF13054.6 EGE05267.1 - 0.015 15.3 4.4 0.023 14.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Usp PF00582.26 EGE05267.1 - 0.39 11.2 8.0 0.82 10.2 0.4 2.1 2 0 0 2 2 2 0 Universal stress protein family MGC-24 PF05283.11 EGE05268.1 - 3.4 8.1 5.8 1.5 9.3 2.5 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PDEase_I PF00233.19 EGE05269.1 - 1.6e-54 185.2 0.0 2.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Rdx PF10262.9 EGE05270.1 - 3.5e-26 91.2 0.0 4.7e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 EGE05271.1 - 0.0012 18.8 0.3 0.0017 18.3 0.3 1.2 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 EGE05272.1 - 3.1e-07 30.9 1.1 1.3e-05 25.7 0.0 3.2 2 0 0 2 2 2 1 PCI domain BAH PF01426.18 EGE05272.1 - 0.037 13.9 3.9 0.11 12.4 3.9 1.8 1 0 0 1 1 1 0 BAH domain Pro_Al_protease PF02983.14 EGE05272.1 - 0.045 13.8 0.0 0.33 11.0 0.0 2.6 1 0 0 1 1 1 0 Alpha-lytic protease prodomain CENP-Q PF13094.6 EGE05273.1 - 0.053 13.7 1.2 0.4 10.9 0.2 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_NinH PF06322.11 EGE05273.1 - 0.067 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage NinH protein Lectin_N PF03954.14 EGE05273.1 - 0.85 9.4 3.8 5.7 6.7 1.4 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Acetyltransf_1 PF00583.25 EGE05274.1 - 3.6e-11 43.3 0.0 4.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE05274.1 - 3.3e-09 36.8 0.0 5.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE05274.1 - 2.3e-06 27.5 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGE05274.1 - 2.3e-06 27.9 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE05274.1 - 0.00018 21.6 0.1 0.00027 21.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGE05274.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EGE05275.1 - 1.5e-21 76.7 54.3 4.4e-17 62.0 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.22 EGE05276.1 - 5.7e-17 61.4 0.1 8.1e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 EGE05277.1 - 5.6e-25 86.4 59.2 0.00076 19.8 0.7 11.6 11 1 1 12 12 12 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE05277.1 - 3.2e-17 61.7 58.5 0.016 16.0 0.7 11.1 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE05277.1 - 1.1e-10 41.5 55.6 0.0033 17.8 0.2 11.0 11 1 1 12 12 11 6 Zinc-finger double domain FOXP-CC PF16159.5 EGE05277.1 - 4.5e-05 24.0 32.7 0.15 12.7 0.2 8.4 6 2 3 9 9 9 3 FOXP coiled-coil domain GAGA PF09237.11 EGE05277.1 - 0.00028 20.6 0.5 0.00028 20.6 0.5 2.2 2 0 0 2 2 2 1 GAGA factor zf-C2H2_jaz PF12171.8 EGE05277.1 - 0.00075 19.7 13.0 2.6 8.4 0.0 7.7 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EGE05277.1 - 0.0088 16.3 19.8 0.16 12.3 2.0 4.5 3 1 3 6 6 6 4 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 EGE05277.1 - 0.016 14.9 20.3 4.4 7.1 0.0 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 EGE05277.1 - 0.023 15.4 16.9 4.5 8.0 0.1 5.1 4 3 1 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_9 PF16293.5 EGE05277.1 - 0.061 13.2 2.5 2.5 8.0 0.7 3.6 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF5472 PF17566.2 EGE05277.1 - 0.11 12.5 3.5 15 5.6 0.1 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5472) CHORD PF04968.12 EGE05277.1 - 1.7 9.4 19.3 2.6 8.9 0.8 5.0 4 1 1 5 5 4 0 CHORD zf-C2H2_aberr PF17017.5 EGE05277.1 - 2.4 8.2 14.2 9.9 6.3 0.6 4.6 3 1 3 6 6 6 0 Aberrant zinc-finger zf-met PF12874.7 EGE05277.1 - 7.3 7.1 12.7 73 4.0 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger of C2H2 type CAP_N PF01213.19 EGE05278.1 - 0.012 15.1 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EGE05278.1 - 0.13 12.3 2.5 0.19 11.8 2.5 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PH PF00169.29 EGE05279.1 - 2.5e-06 27.9 0.0 1.5e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 PH domain COPIIcoated_ERV PF07970.12 EGE05280.1 - 3.3e-80 269.1 0.0 5.4e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGE05280.1 - 1.7e-29 102.0 0.0 4.6e-29 100.6 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 EGE05281.1 - 2.4e-17 62.3 0.7 4.7e-17 61.4 0.7 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 EGE05281.1 - 2.6e-06 27.1 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 EGE05281.1 - 5.6e-06 26.1 0.0 1.8e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 EGE05281.1 - 3e-05 24.6 0.0 7.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 EGE05281.1 - 7.4e-05 23.0 5.6 0.0031 17.9 0.3 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGE05281.1 - 0.015 15.1 0.2 0.039 13.7 0.2 1.8 1 0 0 1 1 1 0 Leucine rich repeat Vps53_N PF04100.12 EGE05282.1 - 5.3e-107 358.1 10.1 1.1e-106 357.0 10.1 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EGE05282.1 - 6.7e-08 32.2 6.8 1.3e-07 31.2 6.8 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGE05282.1 - 9.5e-05 22.3 0.1 0.0008 19.3 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 EGE05282.1 - 0.0038 17.3 3.7 0.0095 16.0 2.4 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Plk4_PB2 PF18409.1 EGE05282.1 - 0.16 12.6 6.6 2.5 8.8 0.6 4.2 2 1 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 Sporozoite_P67 PF05642.11 EGE05282.1 - 0.32 9.0 4.9 0.49 8.4 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen COG5 PF10392.9 EGE05282.1 - 0.32 11.2 7.4 0.42 10.8 3.3 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TRPM_tetra PF16519.5 EGE05282.1 - 0.52 10.4 6.1 0.08 13.0 1.8 1.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM GIT1_C PF12205.8 EGE05282.1 - 0.96 9.6 8.5 1 9.5 1.1 2.8 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DEAD PF00270.29 EGE05283.1 - 6.8e-17 61.8 0.3 2.6e-16 59.9 0.1 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE05283.1 - 4.3e-09 36.7 0.0 1.9e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE05283.1 - 1.9e-07 31.3 0.0 4.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4332 PF14229.6 EGE05283.1 - 0.059 13.6 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) DUF1524 PF07510.11 EGE05285.1 - 1.5e-09 37.8 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EGE05285.1 - 0.02 14.8 2.3 0.058 13.3 0.9 2.3 2 1 0 2 2 2 0 HNH endonuclease RrnaAD PF00398.20 EGE05286.1 - 0.0014 17.7 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Pkinase PF00069.25 EGE05288.1 - 1.2e-10 41.2 0.0 5.5e-10 39.1 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05288.1 - 1.1e-05 24.9 0.0 6.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGE05288.1 - 0.048 13.0 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE05288.1 - 0.07 13.0 0.2 0.69 9.8 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE05288.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 EGE05290.1 - 1.8e-25 88.7 0.7 5.9e-07 30.1 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05290.1 - 1.5e-13 50.8 0.0 0.0065 16.7 0.0 5.0 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE05290.1 - 0.0021 16.8 0.8 0.073 11.7 0.1 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 EGE05290.1 - 0.028 14.2 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EGE05290.1 - 0.1 12.2 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 PQQ-like domain FTHFS PF01268.19 EGE05291.1 - 2e-253 841.6 0.0 3.9e-253 840.7 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EGE05291.1 - 1.2e-66 223.0 0.6 1.2e-66 223.0 0.6 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGE05291.1 - 1.4e-35 122.0 0.2 3.1e-35 120.9 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EGE05291.1 - 0.02 13.9 0.6 0.043 12.7 0.1 1.7 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Iso_dh PF00180.20 EGE05292.1 - 2.6e-70 237.3 0.0 3.2e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MBF1 PF08523.10 EGE05293.1 - 1.1e-26 93.1 0.4 1.1e-26 93.1 0.4 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EGE05293.1 - 1.4e-11 44.3 0.1 3.2e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EGE05293.1 - 4.1e-07 30.2 0.4 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain MFS_1 PF07690.16 EGE05294.1 - 9.8e-15 54.3 64.0 1.5e-13 50.4 52.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SH3_1 PF00018.28 EGE05295.1 - 1.9e-14 53.0 0.0 2.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE05295.1 - 1.5e-12 47.2 0.0 4.7e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGE05295.1 - 1.2e-07 31.3 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Glyco_tranf_2_3 PF13641.6 EGE05297.1 - 1.3e-17 64.4 0.4 1.9e-17 64.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATP12 PF07542.11 EGE05300.1 - 2.8e-42 143.9 0.3 4.1e-42 143.3 0.3 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein UnbV_ASPIC PF07593.12 EGE05300.1 - 0.065 13.2 0.1 0.43 10.6 0.1 2.3 2 1 0 2 2 2 0 ASPIC and UnbV Oxysterol_BP PF01237.18 EGE05301.1 - 1.3e-136 455.3 0.0 3.8e-136 453.8 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EGE05301.1 - 4.2e-17 62.0 0.1 4.8e-10 39.5 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE05301.1 - 1.4e-16 60.8 0.0 8.8e-08 32.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGE05301.1 - 1.1e-12 47.7 0.1 0.0018 18.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGE05301.1 - 6.7e-12 44.5 0.1 0.00081 19.7 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat PH PF00169.29 EGE05301.1 - 3.4e-10 40.4 0.3 8.4e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EGE05301.1 - 9.7e-09 35.6 0.0 0.0006 20.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH_8 PF15409.6 EGE05301.1 - 3.5e-06 27.2 0.7 1.1e-05 25.7 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGE05301.1 - 2.9e-05 24.4 1.6 0.00011 22.6 1.6 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain LLC1 PF14945.6 EGE05301.1 - 0.029 14.9 0.2 0.029 14.9 0.2 2.6 3 0 0 3 3 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RAP1 PF07218.11 EGE05301.1 - 9.2 4.4 7.5 16 3.6 7.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-Mss51 PF13824.6 EGE05302.1 - 4.1e-27 94.0 11.0 1.1e-26 92.6 11.0 1.8 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EGE05302.1 - 0.0047 17.0 2.8 0.0047 17.0 2.8 2.0 2 0 0 2 2 2 1 MYND finger GRP PF07172.11 EGE05303.1 - 9.4 7.0 36.3 2.3e+02 2.5 36.3 2.2 1 1 0 1 1 1 0 Glycine rich protein family ADH_zinc_N PF00107.26 EGE05304.1 - 8e-28 97.0 0.4 1.2e-27 96.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE05304.1 - 1.5e-11 45.4 0.0 3.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE05304.1 - 4.1e-06 26.6 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGE05304.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase adh_short PF00106.25 EGE05304.1 - 0.061 12.8 0.1 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 EGE05304.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HupF_HypC PF01455.18 EGE05304.1 - 0.21 11.8 0.5 0.68 10.1 0.1 2.1 2 0 0 2 2 2 0 HupF/HypC family Pep_deformylase PF01327.21 EGE05304.1 - 0.26 10.9 0.1 0.47 10.0 0.1 1.3 1 0 0 1 1 1 0 Polypeptide deformylase Clr5 PF14420.6 EGE05305.1 - 1.1e-13 51.1 1.2 1.1e-13 51.1 1.2 1.7 2 0 0 2 2 2 1 Clr5 domain SNF2_N PF00176.23 EGE05306.1 - 4.4e-63 213.1 0.7 7e-63 212.5 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE05306.1 - 3.4e-20 72.4 0.0 1.5e-19 70.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 EGE05306.1 - 1.8e-09 37.8 7.2 7.1e-09 35.9 7.2 2.1 1 0 0 1 1 1 1 HSA ResIII PF04851.15 EGE05306.1 - 6e-09 36.1 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE05306.1 - 2.5e-05 24.1 0.1 0.00066 19.5 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase MSA-2c PF12238.8 EGE05306.1 - 0.022 14.7 5.0 0.09 12.8 5.0 2.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF2486 PF10667.9 EGE05306.1 - 0.11 12.7 6.0 0.37 11.0 6.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) NDUF_B8 PF05821.11 EGE05307.1 - 1.8e-06 28.0 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.9 EGE05308.1 - 2.6e-19 69.9 0.2 1.7e-16 60.7 0.2 2.7 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EGE05308.1 - 2.1e-13 50.5 0.0 4.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EGE05308.1 - 1.4e-07 30.5 0.3 1.4e-07 30.5 0.3 1.7 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) Ribonuc_L-PSP PF01042.21 EGE05309.1 - 1e-40 138.5 0.0 1.1e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_10 PF13460.6 EGE05310.1 - 7.2e-11 42.3 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE05310.1 - 2.2e-08 34.0 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGE05310.1 - 0.00025 21.3 0.0 0.00038 20.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EGE05310.1 - 0.00029 21.1 0.1 0.00042 20.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain PglD_N PF17836.1 EGE05310.1 - 0.0018 18.9 0.1 0.0038 17.8 0.1 1.5 1 0 0 1 1 1 1 PglD N-terminal domain Epimerase PF01370.21 EGE05310.1 - 0.0035 16.8 0.0 0.0056 16.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LpxI_N PF17930.1 EGE05310.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 LpxI N-terminal domain CoA_binding_3 PF13727.6 EGE05310.1 - 0.12 12.3 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 CoA-binding domain Lumazine_bd_2 PF12893.7 EGE05311.1 - 6e-27 94.6 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Putative lumazine-binding DUF4878 PF12870.7 EGE05311.1 - 0.0023 18.2 0.2 0.017 15.4 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4878) Catalase PF00199.19 EGE05312.1 - 2.5e-136 454.8 0.0 3.1e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGE05312.1 - 1.8e-05 24.8 0.0 4.7e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive adh_short_C2 PF13561.6 EGE05313.1 - 6.5e-30 104.4 0.0 8.5e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE05313.1 - 3.3e-23 82.2 0.0 4.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE05313.1 - 0.057 13.3 0.1 0.095 12.6 0.1 1.4 1 1 0 1 1 1 0 KR domain Methyltransf_33 PF10017.9 EGE05314.1 - 8.3e-79 264.9 0.0 9.7e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DUF4363 PF14276.6 EGE05314.1 - 0.049 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) BBE PF08031.12 EGE05315.1 - 4.1e-10 39.6 0.3 1e-09 38.3 0.3 1.7 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.23 EGE05315.1 - 6e-09 35.8 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Trp_DMAT PF11991.8 EGE05316.1 - 7.3e-111 371.1 0.0 9.1e-111 370.8 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase TPR_1 PF00515.28 EGE05317.1 - 2.8e-17 61.7 16.4 0.00081 19.1 0.1 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05317.1 - 1.7e-15 55.8 16.1 0.053 13.8 0.1 10.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGE05317.1 - 2e-15 57.0 26.0 0.00013 22.4 0.0 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE05317.1 - 1.1e-13 50.2 26.1 0.0045 17.0 0.1 9.8 11 0 0 11 11 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGE05317.1 - 2.6e-13 49.6 23.1 0.0025 18.5 0.1 10.2 9 1 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05317.1 - 2.3e-08 34.2 26.6 0.0028 17.9 2.4 8.8 7 2 4 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGE05317.1 - 3.7e-08 33.2 13.1 0.087 13.2 0.1 9.1 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE05317.1 - 2.3e-07 31.0 20.8 0.018 15.6 0.1 10.3 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE05317.1 - 2.4e-07 30.3 14.1 0.18 11.9 0.2 7.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE05317.1 - 1.8e-06 28.5 15.5 0.079 13.6 0.2 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE05317.1 - 0.00023 20.8 13.9 0.032 13.9 0.4 7.2 7 1 1 8 8 8 2 TPR repeat TPR_9 PF13371.6 EGE05317.1 - 0.018 15.2 2.2 7.4 6.8 0.1 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 EGE05317.1 - 0.036 14.3 0.2 39 4.8 0.0 4.5 4 0 0 4 4 4 0 PPR repeat MCC-bdg_PDZ PF10506.9 EGE05317.1 - 0.041 13.9 0.6 0.17 11.9 0.0 2.4 2 0 0 2 2 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TPR_10 PF13374.6 EGE05317.1 - 0.051 13.5 16.0 0.1 12.5 0.4 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGE05317.1 - 0.12 12.4 3.0 62 3.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1152 PF06626.12 EGE05317.1 - 0.15 11.2 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Fis1_TPR_C PF14853.6 EGE05317.1 - 0.89 9.7 3.4 3.3 7.8 0.1 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 EGE05317.1 - 7 6.3 10.6 10 5.8 0.4 3.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Acyltransferase PF01553.21 EGE05318.1 - 1.3e-27 96.0 0.0 2.1e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGE05318.1 - 6e-14 51.9 0.1 1.2e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 EGE05319.1 - 2.5e-48 164.8 0.1 4e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGE05319.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 EGE05321.1 - 5.9e-67 225.8 0.2 5.7e-66 222.6 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05321.1 - 2.1e-50 171.4 0.0 4.1e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGE05321.1 - 5.5e-24 84.3 0.0 5.5e-24 84.3 0.0 2.5 3 0 0 3 3 3 1 P21-Rho-binding domain PH_11 PF15413.6 EGE05321.1 - 3.1e-15 56.5 0.1 8.8e-15 55.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 EGE05321.1 - 2.2e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGE05321.1 - 2.5e-05 23.2 0.0 2.5e-05 23.2 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 EGE05321.1 - 5.1e-05 22.4 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 EGE05321.1 - 0.00016 22.1 0.1 0.0004 20.8 0.1 1.7 1 0 0 1 1 1 1 PH domain KIND PF16474.5 EGE05321.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 EGE05321.1 - 0.04 13.0 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGE05321.1 - 1.2 9.0 5.8 1 9.2 0.3 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDRGK PF09756.9 EGE05321.1 - 1.3 8.6 10.6 3 7.4 10.6 1.5 1 0 0 1 1 1 0 DDRGK domain HGTP_anticodon PF03129.20 EGE05323.1 - 4.8e-20 71.5 0.8 4.2e-19 68.5 0.0 2.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGE05323.1 - 4.9e-09 36.4 0.0 7.7e-08 32.5 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 EGE05324.1 - 1.5e-22 80.7 0.1 2.2e-22 80.1 0.1 1.3 1 0 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.11 EGE05324.1 - 0.67 8.0 5.0 0.92 7.5 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EGE05324.1 - 8.9 4.4 20.7 12 4.0 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family SRI PF08236.11 EGE05326.1 - 9.3e-21 73.8 15.2 3.1e-20 72.1 15.2 2.0 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EGE05326.1 - 1.1e-17 64.9 0.4 1.1e-17 64.9 0.4 3.3 3 1 0 3 3 3 1 SET domain AWS PF17907.1 EGE05326.1 - 1.6e-10 40.9 11.9 1.6e-10 40.9 11.9 2.7 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EGE05326.1 - 1.1e-05 25.3 0.2 3.2e-05 23.8 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 EGE05326.1 - 0.033 14.3 0.3 0.089 12.9 0.3 1.8 1 0 0 1 1 1 0 WW domain PHA_synth_III_E PF09712.10 EGE05326.1 - 0.13 11.4 0.4 0.22 10.6 0.4 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Pox_H7 PF04787.12 EGE05326.1 - 0.34 11.4 4.8 0.71 10.4 4.8 1.5 1 0 0 1 1 1 0 Late protein H7 Spc7 PF08317.11 EGE05329.1 - 4.9e-05 22.4 0.4 6.1e-05 22.1 0.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EGE05329.1 - 8.3e-05 22.6 1.1 0.00032 20.8 0.4 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 EGE05329.1 - 0.00031 19.1 2.3 0.00053 18.3 1.7 1.6 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Transcrip_act PF04949.13 EGE05329.1 - 0.00046 20.1 0.1 0.046 13.6 0.0 2.2 1 1 1 2 2 2 1 Transcriptional activator DUF677 PF05055.12 EGE05329.1 - 0.0015 17.5 0.3 0.0019 17.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) TelA PF05816.11 EGE05329.1 - 0.0023 17.0 2.8 0.52 9.3 0.1 2.5 1 1 2 3 3 3 2 Toxic anion resistance protein (TelA) Filament PF00038.21 EGE05329.1 - 0.003 17.2 0.3 0.0041 16.8 0.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein Syntaxin PF00804.25 EGE05329.1 - 0.006 16.3 2.4 0.01 15.5 1.6 1.6 2 0 0 2 2 2 1 Syntaxin Gp58 PF07902.11 EGE05329.1 - 0.008 14.5 0.8 0.01 14.2 0.8 1.1 1 0 0 1 1 1 1 gp58-like protein SHE3 PF17078.5 EGE05329.1 - 0.0085 15.8 1.5 0.012 15.3 1.5 1.3 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Serine_rich PF08824.10 EGE05329.1 - 0.0091 16.0 0.4 0.04 13.9 0.4 1.9 1 1 0 1 1 1 1 Serine rich protein interaction domain DUF812 PF05667.11 EGE05329.1 - 0.0093 14.9 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) NPV_P10 PF05531.12 EGE05329.1 - 0.01 16.3 3.6 0.017 15.5 1.5 2.5 2 1 1 3 3 1 0 Nucleopolyhedrovirus P10 protein 7TMR-HDED PF07697.11 EGE05329.1 - 0.01 15.9 0.5 0.014 15.5 0.5 1.1 1 0 0 1 1 1 0 7TM-HD extracellular ISG65-75 PF11727.8 EGE05329.1 - 0.012 14.9 2.2 0.017 14.4 2.0 1.3 1 1 0 1 1 1 0 Invariant surface glycoprotein FlaC_arch PF05377.11 EGE05329.1 - 0.013 15.9 2.0 2.3 8.7 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ApoLp-III PF07464.11 EGE05329.1 - 0.019 15.1 3.5 0.034 14.2 3.5 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Effector_1 PF04518.12 EGE05329.1 - 0.023 13.8 0.6 0.054 12.6 0.2 1.6 1 1 0 1 1 1 0 Effector from type III secretion system TACC_C PF05010.14 EGE05329.1 - 0.03 14.1 1.1 0.066 13.0 1.0 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RasGAP_C PF03836.15 EGE05329.1 - 0.03 14.5 2.2 0.47 10.6 2.2 2.4 1 1 0 1 1 1 0 RasGAP C-terminus CdvA PF18822.1 EGE05329.1 - 0.033 14.0 1.9 0.13 12.1 0.2 2.4 2 1 1 3 3 2 0 CdvA-like coiled-coil domain APG17 PF04108.12 EGE05329.1 - 0.036 13.2 1.1 0.22 10.6 1.1 1.9 1 1 0 1 1 1 0 Autophagy protein Apg17 IFT57 PF10498.9 EGE05329.1 - 0.047 12.7 0.9 0.06 12.3 0.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CLZ PF16526.5 EGE05329.1 - 0.049 14.0 0.8 0.98 9.8 0.1 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1640 PF07798.11 EGE05329.1 - 0.055 13.5 0.9 0.079 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 EGE05329.1 - 0.057 13.3 0.2 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BLOC1_2 PF10046.9 EGE05329.1 - 0.073 13.4 0.8 4 7.8 0.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EGE05329.1 - 0.073 13.1 2.9 0.18 11.8 1.9 1.9 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 EGE05329.1 - 0.088 13.0 3.2 0.11 12.7 2.3 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlgN PF05130.12 EGE05329.1 - 0.089 13.3 0.6 0.35 11.4 0.6 2.1 1 1 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 EGE05329.1 - 0.09 12.8 4.4 1.9 8.5 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PIN_8 PF18476.1 EGE05329.1 - 0.099 12.5 0.6 0.13 12.1 0.6 1.3 1 0 0 1 1 1 0 PIN like domain Cortex-I_coil PF09304.10 EGE05329.1 - 0.1 12.8 0.6 0.25 11.5 0.6 1.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil HIP1_clath_bdg PF16515.5 EGE05329.1 - 0.11 13.2 0.8 0.38 11.4 0.2 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CorA PF01544.18 EGE05329.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein VasL PF12486.8 EGE05329.1 - 0.11 12.4 0.4 0.36 10.7 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL Spectrin PF00435.21 EGE05329.1 - 0.11 13.0 1.1 5.8 7.5 0.1 2.4 1 1 1 2 2 2 0 Spectrin repeat Vps54 PF07928.12 EGE05329.1 - 0.13 12.7 0.2 0.28 11.6 0.2 1.6 1 0 0 1 1 1 0 Vps54-like protein HBS1_N PF08938.10 EGE05329.1 - 0.16 12.3 0.4 0.64 10.4 0.3 2.0 1 1 1 2 2 2 0 HBS1 N-terminus DUF3206 PF11472.8 EGE05329.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Prefoldin_2 PF01920.20 EGE05329.1 - 0.19 11.7 1.9 5.3 7.1 0.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit YkyA PF10368.9 EGE05329.1 - 0.22 11.2 2.8 0.59 9.8 2.8 1.7 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF948 PF06103.11 EGE05329.1 - 0.34 11.2 2.3 2.8 8.3 0.3 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EGE05329.1 - 0.6 10.6 3.5 1.4 9.4 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4820 PF16091.5 EGE05331.1 - 0.17 11.2 3.5 0.26 10.6 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 EGE05331.1 - 2.6 6.7 7.1 2.7 6.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 EGE05331.1 - 5.3 6.5 11.1 7 6.1 11.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 EGE05331.1 - 6.1 6.2 14.2 8.4 5.7 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 EGE05331.1 - 7.4 4.5 10.8 8.9 4.3 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi API5 PF05918.11 EGE05331.1 - 8.6 5.0 9.3 11 4.6 9.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Myc_N PF01056.18 EGE05331.1 - 9.5 6.0 8.4 14 5.4 8.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.12 EGE05331.1 - 9.7 5.9 10.4 12 5.7 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AT_hook PF02178.19 EGE05332.1 - 0.017 15.0 1.5 0.077 12.9 1.5 2.2 1 0 0 1 1 1 0 AT hook motif BAR PF03114.18 EGE05333.1 - 6.6e-47 160.2 2.6 1.3e-46 159.2 2.6 1.4 1 1 0 1 1 1 1 BAR domain CP12 PF02672.15 EGE05333.1 - 0.012 16.3 0.5 0.051 14.3 0.0 2.3 3 1 0 3 3 3 0 CP12 domain Pkinase PF00069.25 EGE05335.1 - 4e-50 170.6 0.0 5.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05335.1 - 4e-27 95.1 0.0 5.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE05335.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE05335.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sybindin PF04099.12 EGE05337.1 - 6.3e-25 87.8 0.0 7.9e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGE05337.1 - 0.0037 17.4 0.2 0.0051 16.9 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EGE05338.1 - 1.1e-56 192.1 0.0 6.8e-51 173.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05338.1 - 5.4e-35 120.9 0.0 3.6e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGE05338.1 - 1e-08 34.9 0.0 4.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGE05338.1 - 0.0009 19.2 0.0 0.0045 16.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE05338.1 - 0.0025 16.6 0.0 0.012 14.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pept_tRNA_hydro PF01195.19 EGE05339.1 - 3.8e-23 82.3 0.0 3.6e-20 72.6 0.0 2.8 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF2263 PF10021.9 EGE05340.1 - 0.016 15.5 0.2 0.2 12.0 0.2 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2263) Methyltransf_23 PF13489.6 EGE05341.1 - 1.3e-10 41.3 0.0 2.8e-10 40.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE05341.1 - 9.1e-08 32.7 0.0 2.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05341.1 - 9.7e-06 25.5 0.0 4.9e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE05341.1 - 2.9e-05 24.7 0.0 0.00027 21.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE05341.1 - 0.0025 18.4 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGE05341.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EGE05341.1 - 0.013 15.1 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 EGE05341.1 - 0.013 15.6 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGE05341.1 - 0.026 14.0 0.0 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 EGE05341.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TP6A_N PF04406.14 EGE05342.1 - 2e-18 66.1 0.0 4.8e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase UQ_con PF00179.26 EGE05343.1 - 1.3e-48 164.2 0.0 1.5e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Scramblase PF03803.15 EGE05344.1 - 1.4e-55 188.0 0.0 4.4e-54 183.1 0.0 2.6 1 1 0 1 1 1 1 Scramblase Ribosomal_L27 PF01016.19 EGE05346.1 - 8e-32 109.1 1.1 1.4e-31 108.4 1.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Rad9_Rad53_bind PF08605.10 EGE05347.1 - 9.1e-17 61.5 0.0 1.7e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 EGE05347.1 - 2.1e-16 59.5 0.0 4.3e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 EGE05347.1 - 1.6e-07 31.6 0.0 6e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGE05347.1 - 1e-06 29.0 0.0 2.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EGE05347.1 - 3.2e-05 23.7 0.0 0.00024 20.9 0.0 2.3 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EGE05347.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Anillin_N PF16018.5 EGE05347.1 - 6.1 7.5 11.0 6.7 7.4 0.2 4.9 4 0 0 4 4 4 0 Anillin N-terminus tRNA_int_endo PF01974.17 EGE05348.1 - 1.5e-17 63.4 0.4 4.3e-17 62.0 0.4 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGE05348.1 - 0.00037 20.1 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Nop10p PF04135.12 EGE05349.1 - 3.6e-22 78.1 0.6 4.2e-22 77.9 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.11 EGE05350.1 - 6e-33 112.8 3.2 1.2e-32 111.8 3.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EGE05350.1 - 2.5e-30 104.8 0.3 1.8e-29 102.0 0.1 2.5 3 0 0 3 3 3 1 PIN domain of ribonuclease HypA PF01155.19 EGE05350.1 - 0.0043 17.0 0.2 0.15 12.1 0.2 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 EGE05350.1 - 0.0061 16.2 0.6 0.0061 16.2 0.6 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_15 PF17032.5 EGE05350.1 - 0.055 14.2 0.2 0.12 13.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon family SDA1 PF05285.12 EGE05350.1 - 0.083 12.3 6.6 0.0092 15.4 2.6 1.3 2 0 0 2 2 2 0 SDA1 SWIRM-assoc_2 PF16496.5 EGE05350.1 - 0.32 9.8 7.9 0.52 9.1 7.9 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Zn-ribbon_8 PF09723.10 EGE05350.1 - 0.58 10.3 6.2 0.19 11.9 1.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_M18 PF02127.15 EGE05351.1 - 1.9e-133 445.5 0.0 2.2e-133 445.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) ABC_tran PF00005.27 EGE05352.1 - 5.6e-51 172.7 0.0 1.7e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGE05352.1 - 6.6e-23 82.0 1.1 0.00012 22.0 0.0 4.3 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGE05352.1 - 1.5e-21 76.9 43.5 2.7e-13 49.8 22.9 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 EGE05352.1 - 8.4e-10 38.4 1.1 0.004 16.6 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE05352.1 - 2.7e-09 36.6 1.7 6.9e-05 22.5 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EGE05352.1 - 9e-08 32.9 2.9 0.007 16.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EGE05352.1 - 6.7e-06 25.8 0.4 0.098 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGE05352.1 - 1.8e-05 24.7 0.2 0.058 13.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EGE05352.1 - 4.6e-05 23.3 0.0 0.026 14.2 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 EGE05352.1 - 0.00046 20.8 0.0 0.019 15.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 EGE05352.1 - 0.00057 20.3 0.0 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EGE05352.1 - 0.0008 19.2 0.9 0.42 10.3 0.2 2.8 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.6 EGE05352.1 - 0.0053 17.0 0.2 7.9 6.8 0.1 4.0 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EGE05352.1 - 0.017 15.4 0.1 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGE05352.1 - 0.023 14.3 0.7 2.9 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGE05352.1 - 0.047 13.3 0.5 8.4 6.0 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EGE05352.1 - 0.06 13.4 0.6 4 7.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGE05352.1 - 0.08 12.2 0.3 11 5.3 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 EGE05352.1 - 0.19 12.0 0.2 25 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EGE05352.1 - 0.26 9.9 0.7 6.1 5.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 EGE05353.1 - 1.5e-36 126.1 23.9 4.3e-36 124.6 23.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATPase_gene1 PF09527.10 EGE05353.1 - 0.1 12.8 0.2 0.1 12.8 0.2 4.7 5 1 0 5 5 5 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ABC2_membrane PF01061.24 EGE05354.1 - 3.1e-80 268.6 54.7 4.3e-41 140.6 12.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGE05354.1 - 1.3e-33 116.4 0.0 9e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGE05354.1 - 2.3e-20 72.3 0.0 2.3e-20 72.3 0.0 2.2 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.6 EGE05354.1 - 2.4e-11 44.1 0.0 1.1e-10 42.0 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EGE05354.1 - 8.8e-06 25.7 0.0 0.14 11.9 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGE05354.1 - 2.3e-05 24.8 0.0 0.014 15.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EGE05354.1 - 4.1e-05 23.8 0.5 0.0014 18.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGE05354.1 - 0.00013 22.5 0.0 0.0035 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGE05354.1 - 0.0014 18.2 0.1 0.017 14.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE05354.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGE05354.1 - 0.0019 17.9 0.4 0.014 15.1 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGE05354.1 - 0.0043 17.3 0.1 0.11 12.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGE05354.1 - 0.0092 15.1 49.8 0.02 14.0 23.8 3.6 2 1 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 EGE05354.1 - 0.015 14.8 0.0 0.67 9.3 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE05354.1 - 0.054 13.8 0.2 0.37 11.1 0.2 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGE05354.1 - 0.061 13.7 0.1 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGE05354.1 - 0.071 12.7 0.4 0.16 11.6 0.4 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP-grasp_5 PF13549.6 EGE05354.1 - 0.15 11.5 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PRK PF00485.18 EGE05354.1 - 0.18 11.6 0.1 25 4.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EGE05354.1 - 0.33 11.4 0.0 0.33 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Adap_comp_sub PF00928.21 EGE05358.1 - 5.9e-91 304.5 0.0 9.2e-91 303.9 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGE05358.1 - 1.4e-09 38.0 0.1 2.4e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EGE05358.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 EGE05359.1 - 1.8e-27 96.0 0.0 2.9e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGE05359.1 - 4.7e-06 27.2 0.0 9.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.22 EGE05360.1 - 7.2e-24 84.1 3.9 9.5e-24 83.7 3.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.15 EGE05361.1 - 1.3e-57 195.7 0.4 1.4e-56 192.3 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGE05361.1 - 2.5e-14 53.0 0.0 1.2e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGE05361.1 - 0.0012 18.0 0.2 0.0021 17.2 0.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NanE PF04131.14 EGE05361.1 - 0.021 14.0 0.3 0.056 12.6 0.1 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SCP1201-deam PF14428.6 EGE05362.1 - 0.008 16.1 0.1 0.008 16.1 0.1 2.3 3 0 0 3 3 3 1 SCP1.201-like deaminase Hydrophobin PF01185.18 EGE05363.1 - 1.9e-07 31.6 10.9 2.6e-07 31.2 10.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin WW PF00397.26 EGE05364.1 - 3.6e-10 39.8 2.0 3.6e-10 39.8 2.0 2.3 2 0 0 2 2 2 1 WW domain WRW PF10206.9 EGE05364.1 - 0.094 13.1 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_2 PF12796.7 EGE05365.1 - 5.5e-13 49.3 0.8 7.3e-12 45.7 0.7 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGE05365.1 - 4.2e-11 42.8 0.6 8.3e-07 29.2 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGE05365.1 - 5.8e-10 39.2 1.7 2.4e-07 30.9 0.4 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE05365.1 - 3.4e-09 36.2 0.3 6.4e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGE05365.1 - 1.7e-08 34.8 0.2 8.1e-08 32.7 0.2 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Glyco_transf_21 PF13506.6 EGE05366.1 - 5.3e-06 26.0 0.0 0.23 10.9 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EGE05366.1 - 0.00064 19.7 0.0 0.0023 17.8 0.0 1.8 1 1 1 2 2 2 1 Glycosyltransferase like family 2 E1-E2_ATPase PF00122.20 EGE05367.1 - 7.9e-38 129.8 1.1 2.3e-37 128.3 1.1 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE05367.1 - 1.8e-34 119.0 4.2 1.8e-34 119.0 4.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGE05367.1 - 6.7e-17 61.4 0.0 1.9e-16 59.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE05367.1 - 1.7e-14 54.6 0.1 5.2e-09 36.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE05367.1 - 2.6e-08 33.4 0.0 6.7e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGE05367.1 - 1.6e-05 24.8 0.8 3e-05 23.9 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGE05367.1 - 0.013 15.3 7.4 0.46 10.3 0.6 3.1 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) PGG PF13962.6 EGE05367.1 - 0.52 10.2 7.7 0.2 11.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF4133 PF13571.6 EGE05367.1 - 1.8 9.0 4.0 0.92 9.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) HAT_KAT11 PF08214.11 EGE05368.1 - 5.6e-94 315.3 0.0 7e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Cupin_2 PF07883.11 EGE05369.1 - 5.1e-07 29.3 0.0 9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EGE05369.1 - 0.011 15.7 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Mtd_N PF18454.1 EGE05369.1 - 0.21 11.6 0.3 64 3.7 0.1 3.1 3 0 0 3 3 3 0 Major tropism determinant N-terminal domain Hid1 PF12722.7 EGE05371.1 - 0 1099.0 0.0 0 1098.8 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EGE05371.1 - 3.9e-99 332.8 0.0 4.8e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein BC10 PF06726.12 EGE05371.1 - 0.076 13.3 0.1 0.29 11.4 0.1 2.0 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Vps54 PF07928.12 EGE05376.1 - 4.1e-50 169.7 0.1 1.8e-49 167.6 0.0 2.2 2 0 0 2 2 2 1 Vps54-like protein DUF2451 PF10474.9 EGE05376.1 - 7.9e-09 35.6 0.1 5.6e-08 32.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EGE05376.1 - 2e-05 24.1 0.2 6.2e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Cytochrom_B562 PF07361.11 EGE05376.1 - 0.061 14.0 0.4 0.2 12.3 0.4 1.9 1 0 0 1 1 1 0 Cytochrome b562 DUF4363 PF14276.6 EGE05376.1 - 0.092 12.9 0.3 2.1 8.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Pkinase PF00069.25 EGE05378.1 - 3.2e-26 92.3 0.0 1.6e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05378.1 - 5e-09 35.8 0.0 0.0028 17.0 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE05378.1 - 0.045 12.5 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGE05378.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family MCM PF00493.23 EGE05379.1 - 6.8e-104 345.9 0.1 1.4e-103 344.9 0.1 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGE05379.1 - 5.3e-37 126.5 0.9 1e-36 125.6 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGE05379.1 - 7.4e-29 100.0 1.0 1.9e-28 98.7 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGE05379.1 - 2.3e-16 60.3 0.5 5.3e-16 59.1 0.5 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE05379.1 - 8.9e-07 28.5 0.0 0.00014 21.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE05379.1 - 2.3e-05 24.4 0.0 4.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGE05379.1 - 0.00085 19.2 0.0 0.0033 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EGE05379.1 - 0.0013 18.9 0.2 0.0052 17.0 0.1 2.1 2 0 0 2 2 2 1 Midasin AAA lid domain Sigma54_activat PF00158.26 EGE05379.1 - 0.023 14.4 0.1 0.26 11.0 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain ECH_1 PF00378.20 EGE05380.1 - 8.3e-36 123.6 0.1 3.1e-23 82.4 0.2 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE05380.1 - 6.6e-17 62.0 0.0 3.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase PfkB PF00294.24 EGE05381.1 - 5.3e-42 144.2 0.0 8.7e-42 143.5 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase p6 PF17548.2 EGE05381.1 - 0.024 14.6 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 Histone-like Protein p6 PAN_1 PF00024.26 EGE05382.1 - 3.1e-08 33.5 23.5 0.00021 21.2 4.8 2.8 2 2 1 3 3 3 2 PAN domain PAN_4 PF14295.6 EGE05382.1 - 0.0044 16.9 5.3 0.0044 16.9 5.3 3.7 2 2 1 3 3 3 2 PAN domain FAP PF07174.11 EGE05383.1 - 0.72 9.3 19.9 0.71 9.3 19.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Mito_fiss_reg PF05308.11 EGE05383.1 - 9.1 6.3 8.2 11 6.0 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator 2OG-FeII_Oxy_3 PF13640.6 EGE05384.1 - 1e-10 42.4 0.0 1.5e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGE05384.1 - 0.024 15.1 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Tau95 PF09734.9 EGE05386.1 - 6.9e-40 137.1 0.6 1.6e-39 135.9 0.6 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EGE05386.1 - 9.8e-39 132.4 0.4 1.7e-38 131.6 0.0 1.6 2 0 0 2 2 2 1 Tau95 Triple barrel domain B56 PF01603.20 EGE05387.1 - 1.6e-189 630.2 4.3 1.9e-189 629.9 4.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EGE05387.1 - 0.0028 17.6 2.9 0.99 9.3 0.1 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal FAT PF02259.23 EGE05388.1 - 9.3e-72 242.1 13.3 1.9e-71 241.1 13.3 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EGE05388.1 - 1.2e-34 120.2 0.0 2.9e-34 119.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EGE05388.1 - 7e-06 25.8 0.1 2e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 FATC domain Gluconate_2-dh3 PF13618.6 EGE05388.1 - 0.026 14.8 0.1 3.9 7.7 0.0 3.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 DUF2576 PF10845.8 EGE05388.1 - 0.11 12.1 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) HEAT PF02985.22 EGE05388.1 - 0.18 12.2 0.2 38 4.9 0.1 4.5 3 0 0 3 3 3 0 HEAT repeat DUF572 PF04502.13 EGE05389.1 - 8.3e-70 236.0 12.8 9.9e-70 235.8 12.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Trypan_glycop PF00913.19 EGE05389.1 - 0.039 13.2 0.3 0.052 12.8 0.3 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF951 PF06107.11 EGE05389.1 - 0.041 13.8 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) HypA PF01155.19 EGE05389.1 - 0.07 13.1 0.6 2 8.5 0.1 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 EGE05389.1 - 0.11 12.2 2.4 7.8 6.3 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-FCS PF06467.14 EGE05389.1 - 0.11 12.4 3.6 0.75 9.8 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TF_Zn_Ribbon PF08271.12 EGE05389.1 - 0.52 9.9 6.0 0.88 9.1 1.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EGE05389.1 - 0.78 9.5 3.6 1.1 9.0 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 EGE05389.1 - 2.2 8.4 5.5 3.4 7.8 0.8 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_SprT PF17283.2 EGE05389.1 - 3.5 7.6 6.0 5.3 7.0 0.5 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain TPR_2 PF07719.17 EGE05390.1 - 1.3e-27 93.7 10.7 0.00096 19.1 0.3 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGE05390.1 - 9.1e-25 85.4 7.9 0.00035 20.3 0.8 10.3 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE05390.1 - 1.3e-22 79.8 21.4 4.3e-21 74.9 1.7 5.6 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGE05390.1 - 1.2e-15 57.8 13.2 0.0024 18.4 0.0 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05390.1 - 3.3e-15 55.0 10.0 0.012 15.7 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05390.1 - 1.2e-14 54.3 23.7 4e-08 33.4 0.3 9.9 7 3 3 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE05390.1 - 6.5e-11 42.7 16.3 0.053 14.2 0.6 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE05390.1 - 2.2e-10 40.4 15.6 1.7 9.7 0.4 8.5 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGE05390.1 - 1.9e-09 37.1 17.5 0.00011 21.9 0.1 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE05390.1 - 6.8e-07 28.9 8.0 0.36 10.5 0.1 6.9 7 1 1 8 8 8 2 TPR repeat TPR_6 PF13174.6 EGE05390.1 - 2.7e-06 27.7 8.9 2.9 8.7 0.2 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE05390.1 - 3.9e-06 26.5 22.9 0.88 9.7 0.1 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGE05390.1 - 0.0013 19.0 11.4 7.6 7.2 0.0 7.8 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGE05390.1 - 0.0069 16.1 2.6 5.4 6.7 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 EGE05390.1 - 0.0097 15.9 0.2 0.9 9.6 0.0 3.5 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_4 PF07721.14 EGE05390.1 - 0.47 11.2 12.4 0.21 12.3 0.4 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EGE05391.1 - 1.4e-07 30.9 0.0 3.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05391.1 - 1.9e-06 27.9 12.2 3.9e-06 26.9 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 EGE05392.1 - 2.2e-26 92.5 3.5 2.2e-26 92.5 3.5 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Oxidored_q4 PF00507.19 EGE05392.1 - 9.6 6.4 9.7 0.46 10.7 3.7 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Glyco_hydro_17 PF00332.18 EGE05394.1 - 1.2e-08 35.0 2.8 4.2e-05 23.3 1.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 TFIIA PF03153.13 EGE05395.1 - 0.00051 20.2 13.9 0.00067 19.8 13.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGE05395.1 - 0.56 8.4 20.0 0.72 8.0 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 EGE05395.1 - 1.6 8.2 12.6 1.4 8.4 11.3 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4986 PF16375.5 EGE05397.1 - 0.043 14.5 0.0 0.05 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function SRR1 PF07985.12 EGE05398.1 - 7.5e-15 54.7 0.1 2.4e-14 53.1 0.1 1.8 1 1 0 1 1 1 1 SRR1 RRP7 PF12923.7 EGE05398.1 - 0.2 11.8 1.0 0.31 11.2 0.1 1.7 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain YhhN PF07947.14 EGE05401.1 - 7.7e-44 149.5 2.4 1.3e-43 148.8 2.4 1.3 1 1 0 1 1 1 1 YhhN family MFS_1 PF07690.16 EGE05402.1 - 1.5e-05 24.1 14.2 7.1e-05 21.9 7.4 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily eIF-5a PF01287.20 EGE05403.1 - 0.00018 21.5 0.1 0.00036 20.6 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold F-box-like_2 PF13013.6 EGE05404.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.5 1 1 0 1 1 1 0 F-box-like domain F-box-like_2 PF13013.6 EGE05405.1 - 0.0089 16.0 0.2 0.034 14.1 0.2 1.9 1 1 0 1 1 1 1 F-box-like domain PigN PF04987.14 EGE05406.1 - 2.1e-09 36.7 1.9 0.00041 19.3 1.4 2.2 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGE05406.1 - 0.00045 19.9 0.9 0.0077 15.9 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MARVEL PF01284.23 EGE05410.1 - 2.4e-10 40.6 3.5 3.7e-10 40.0 3.5 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF1752 PF08550.10 EGE05411.1 - 1.7e-10 40.5 3.5 3.8e-10 39.4 3.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF5327 PF17261.2 EGE05411.1 - 0.33 11.7 6.5 0.13 13.0 1.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) adh_short_C2 PF13561.6 EGE05412.1 - 4.7e-52 176.9 0.0 6.2e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE05412.1 - 1.4e-35 122.5 0.0 2.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE05412.1 - 1.3e-11 44.7 0.1 2.4e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE05412.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE05412.1 - 0.028 13.8 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CPSase_L_D2 PF02786.17 EGE05413.1 - 8.7e-74 247.6 0.0 1.3e-73 247.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EGE05413.1 - 2.2e-36 124.2 0.0 4.8e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EGE05413.1 - 2.3e-35 121.5 0.0 5e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EGE05413.1 - 6.9e-15 54.7 3.5 7.7e-15 54.5 2.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGE05413.1 - 1.9e-09 37.3 0.0 4.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGE05413.1 - 2.2e-08 33.9 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EGE05413.1 - 1.4e-05 24.9 0.3 0.12 12.2 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EGE05413.1 - 0.00051 20.1 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGE05413.1 - 0.0017 19.0 0.2 0.86 10.3 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.19 EGE05413.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EGE05413.1 - 0.0092 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EGE05413.1 - 0.015 15.2 0.4 0.035 14.0 0.2 1.7 2 0 0 2 2 1 0 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 EGE05413.1 - 0.02 14.5 0.0 0.069 12.7 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 EGE05413.1 - 0.079 12.2 0.1 3.9 6.6 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 EGE05413.1 - 0.18 11.4 0.0 0.53 9.9 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF4947 PF16305.5 EGE05414.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) Acyl-CoA_dh_1 PF00441.24 EGE05415.1 - 2.4e-40 138.2 0.5 4.6e-40 137.3 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGE05415.1 - 4.5e-35 120.7 0.1 9.9e-35 119.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGE05415.1 - 1.3e-26 92.7 0.1 2.6e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGE05415.1 - 6.6e-16 58.8 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGE05415.1 - 0.00019 21.2 0.3 0.00047 19.9 0.3 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 EGE05416.1 - 2.6e-127 425.5 0.0 3e-127 425.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGE05416.1 - 0.036 13.5 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Ras PF00071.22 EGE05417.1 - 7.3e-36 123.2 0.0 1.5e-34 119.0 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGE05417.1 - 1.5e-08 34.8 0.0 1.2e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE05417.1 - 3.5e-06 26.6 0.0 1.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGE05417.1 - 0.00058 19.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGE05417.1 - 0.044 14.0 0.2 0.4 11.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGE05417.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGE05417.1 - 0.23 11.8 0.7 0.82 10.0 0.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain Abhydrolase_1 PF00561.20 EGE05418.1 - 9.2e-25 87.7 0.1 9.5e-24 84.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EGE05418.1 - 6.4e-24 83.3 0.1 1.3e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 EGE05418.1 - 0.00028 20.6 0.1 0.41 10.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGE05418.1 - 0.00061 19.1 0.0 0.053 12.8 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGE05418.1 - 0.049 13.4 0.2 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.9 EGE05419.1 - 2.2e-27 95.1 6.7 2.8e-27 94.8 6.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGE05419.1 - 0.0035 17.3 10.1 0.099 12.7 1.6 2.7 1 1 2 3 3 3 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EGE05419.1 - 0.011 15.7 4.7 1.4 9.0 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COBRA PF04833.15 EGE05419.1 - 0.016 15.1 0.5 0.019 14.9 0.5 1.1 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 EGE05419.1 - 0.023 14.5 0.3 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.14 EGE05420.1 - 2.2e-158 527.4 0.0 2.6e-158 527.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta NADHdh_A3 PF14987.6 EGE05421.1 - 0.023 15.0 0.2 0.03 14.6 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 FAM76 PF16046.5 EGE05423.1 - 0.0028 17.1 5.1 0.015 14.6 0.2 2.1 1 1 1 2 2 2 1 FAM76 protein SDA1 PF05285.12 EGE05423.1 - 0.012 15.0 10.8 0.019 14.4 10.8 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGE05423.1 - 0.019 13.1 10.3 0.026 12.7 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EGE05423.1 - 0.02 14.6 9.1 0.11 12.1 1.9 2.2 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.11 EGE05423.1 - 0.026 13.1 3.8 0.034 12.7 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Spt5_N PF11942.8 EGE05423.1 - 0.16 12.9 20.2 0.4 11.7 6.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal GOLD_2 PF13897.6 EGE05423.1 - 0.37 11.3 6.6 3.4 8.2 0.9 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Sigma70_ner PF04546.13 EGE05423.1 - 0.46 10.3 9.5 0.21 11.5 0.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 EGE05423.1 - 0.48 10.2 11.1 4.1 7.1 4.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EGE05423.1 - 0.59 8.4 11.6 0.21 9.9 3.3 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF4611 PF15387.6 EGE05423.1 - 0.7 10.2 15.2 0.15 12.3 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LAT PF15234.6 EGE05423.1 - 0.94 9.2 5.9 7.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells Presenilin PF01080.17 EGE05423.1 - 2.3 6.9 3.1 3 6.5 3.1 1.3 1 0 0 1 1 1 0 Presenilin CENP-B_dimeris PF09026.10 EGE05423.1 - 2.7 8.4 20.8 6.4 7.2 10.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain WRNPLPNID PF15017.6 EGE05423.1 - 2.9 8.8 15.5 6.4 7.7 3.0 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DUF3245 PF11595.8 EGE05423.1 - 4.8 7.7 15.7 6.1 7.3 9.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) GST_C_2 PF13410.6 EGE05424.1 - 7.6e-07 29.1 0.5 1.9e-06 27.8 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE05424.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGE05424.1 - 0.0011 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE05424.1 - 0.0035 17.5 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE05424.1 - 0.016 15.9 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF2306 PF10067.9 EGE05427.1 - 1.5e-17 64.1 4.1 1.5e-17 64.1 4.1 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EGE05427.1 - 0.0014 18.9 0.5 0.0014 18.9 0.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF420) Sugar_tr PF00083.24 EGE05428.1 - 2.6e-81 273.8 21.7 3e-81 273.6 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE05428.1 - 1.9e-28 99.4 38.4 1.9e-24 86.2 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 EGE05430.1 - 3.9e-67 225.0 0.0 1.3e-32 113.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE05430.1 - 3.9e-48 164.5 45.0 7.4e-21 75.0 9.3 5.1 4 1 1 5 5 5 5 ABC transporter transmembrane region SMC_N PF02463.19 EGE05430.1 - 2.4e-14 53.3 0.0 5e-05 22.8 0.0 3.5 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE05430.1 - 2.9e-07 30.1 0.0 0.0034 17.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EGE05430.1 - 1.2e-06 27.6 0.4 0.034 13.0 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EGE05430.1 - 2.7e-06 27.9 1.8 0.092 13.1 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EGE05430.1 - 9.2e-06 25.6 0.1 0.14 11.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGE05430.1 - 1.8e-05 24.7 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGE05430.1 - 0.00029 20.7 4.1 0.76 9.5 0.2 3.9 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGE05430.1 - 0.0016 18.7 2.8 1.9 8.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 EGE05430.1 - 0.0018 17.5 0.0 0.93 8.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 EGE05430.1 - 0.0022 17.6 0.0 0.51 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGE05430.1 - 0.005 16.6 3.3 2.5 7.8 0.6 3.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EGE05430.1 - 0.0063 16.5 0.1 2.2 8.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EGE05430.1 - 0.0069 16.6 3.1 3.8 7.8 0.5 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EGE05430.1 - 0.0094 16.5 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGE05430.1 - 0.0095 16.1 0.1 5.3 7.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE05430.1 - 0.01 16.4 0.0 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGE05430.1 - 0.01 16.1 1.1 0.84 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGE05430.1 - 0.012 14.9 1.7 1.1 8.5 0.0 3.2 4 0 0 4 4 4 0 Zeta toxin DUF87 PF01935.17 EGE05430.1 - 0.013 15.6 0.9 0.3 11.2 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 EGE05430.1 - 0.02 14.4 0.1 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EGE05430.1 - 0.057 12.6 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGE05430.1 - 0.059 13.8 0.3 9.3 6.7 0.0 3.2 4 0 0 4 4 3 0 RNA helicase PRK PF00485.18 EGE05430.1 - 0.12 12.1 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 EGE05430.1 - 0.16 11.9 0.1 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EGE05430.1 - 0.27 11.3 0.7 21 5.2 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ADH_N PF08240.12 EGE05431.1 - 7.9e-27 93.3 6.1 1.4e-26 92.5 6.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE05431.1 - 8.6e-15 54.9 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGE05431.1 - 0.0004 19.8 0.1 0.00065 19.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EGE05431.1 - 0.0038 17.0 0.1 0.0061 16.3 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EGE05431.1 - 0.0068 15.7 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 EGE05431.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Mito_carr PF00153.27 EGE05432.1 - 3.1e-40 136.0 8.9 4.2e-16 58.6 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ferric_reduct PF01794.19 EGE05433.1 - 3.4e-19 69.2 13.6 3.4e-19 69.2 13.6 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGE05433.1 - 2.1e-13 50.7 0.0 3.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGE05433.1 - 3.7e-13 49.5 0.0 9.6e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain ABC1 PF03109.16 EGE05434.1 - 1.8e-21 76.5 0.1 4.9e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGE05434.1 - 0.05 13.5 0.8 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family IMS PF00817.20 EGE05435.1 - 9.8e-36 123.0 0.0 1.5e-21 76.9 0.0 2.4 2 0 0 2 2 2 2 impB/mucB/samB family zf_UBZ PF18439.1 EGE05435.1 - 2.9e-12 45.9 1.0 6.1e-12 44.9 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_C PF11799.8 EGE05435.1 - 1.7e-11 44.9 0.0 3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain WSC PF01822.19 EGE05439.1 - 2e-07 31.1 9.1 2e-07 31.1 9.1 2.3 2 0 0 2 2 2 1 WSC domain FixQ PF05545.11 EGE05439.1 - 0.027 14.5 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2207 PF09972.9 EGE05439.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Apt1 PF10351.9 EGE05439.1 - 0.73 8.6 16.2 1.3 7.8 16.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EGE05439.1 - 0.96 8.6 37.6 1.5 8.0 37.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 EGE05439.1 - 4 6.8 8.0 20 4.5 8.0 1.9 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Transp_cyt_pur PF02133.15 EGE05440.1 - 7.7e-26 90.8 32.3 7.7e-26 90.8 32.3 1.5 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin PRP38 PF03371.15 EGE05442.1 - 9.1e-65 217.8 0.0 1.2e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 EGE05442.1 - 0.18 11.8 2.4 0.37 10.8 2.4 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain WD40 PF00400.32 EGE05444.1 - 5.5e-16 58.7 5.5 0.25 12.3 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05444.1 - 0.0053 17.0 0.0 7.3 7.0 0.0 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Trypan_PARP PF05887.11 EGE05444.1 - 0.013 15.5 5.3 0.013 15.5 5.3 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PALB2_WD40 PF16756.5 EGE05444.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain AAA_12 PF13087.6 EGE05445.1 - 6.9e-38 130.3 0.0 1.1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE05445.1 - 7.1e-25 88.3 0.0 2.4e-24 86.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGE05445.1 - 9.5e-10 38.5 0.0 3.6e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGE05445.1 - 2.1e-09 37.9 0.0 3.1e-08 34.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGE05445.1 - 5.7e-07 29.5 0.1 0.00042 20.1 0.0 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGE05445.1 - 0.00027 21.0 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE05445.1 - 0.00074 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 EGE05445.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 EGE05445.1 - 0.0084 15.4 0.1 0.38 9.9 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EGE05446.1 - 1.9e-56 190.4 0.2 6.6e-31 107.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE05446.1 - 7.6e-51 173.4 30.0 1.4e-33 116.7 13.1 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EGE05446.1 - 3.4e-07 29.9 8.7 0.019 14.4 0.5 4.6 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGE05446.1 - 2.7e-06 27.4 2.1 0.052 13.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGE05446.1 - 1e-05 25.6 0.2 0.034 14.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE05446.1 - 1.1e-05 25.4 0.3 0.15 12.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGE05446.1 - 3.4e-05 24.5 8.1 0.00062 20.3 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EGE05446.1 - 0.00017 21.3 1.1 0.5 10.1 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGE05446.1 - 0.00054 20.1 1.2 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EGE05446.1 - 0.0017 18.7 0.5 8.2 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGE05446.1 - 0.002 17.8 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGE05446.1 - 0.0024 17.0 0.2 0.027 13.5 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 EGE05446.1 - 0.013 15.9 0.3 3.1 8.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE05446.1 - 0.016 15.6 2.7 3.8 7.8 0.0 3.2 3 1 0 3 3 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EGE05446.1 - 0.016 14.5 0.4 1.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 EGE05446.1 - 0.031 14.0 2.1 3 7.6 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGE05446.1 - 0.04 13.4 0.2 10 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGE05446.1 - 0.046 13.1 0.5 0.46 9.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EGE05446.1 - 0.066 13.8 0.0 14 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGE05446.1 - 0.072 13.1 0.0 12 5.9 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE05446.1 - 0.12 12.2 0.1 3.1 7.5 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_15 PF13175.6 EGE05446.1 - 0.22 11.2 3.3 0.8 9.3 0.0 2.8 4 0 0 4 4 2 0 AAA ATPase domain Adeno_IVa2 PF02456.15 EGE05446.1 - 0.22 10.3 0.5 0.76 8.5 0.1 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.9 EGE05446.1 - 0.31 9.9 2.0 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EGE05446.1 - 0.31 10.6 2.5 0.92 9.1 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGE05446.1 - 0.47 10.3 2.8 5.4 6.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EGE05446.1 - 4.7 7.3 6.7 9.9 6.2 0.4 3.0 3 0 0 3 3 3 0 Dynamin family Peptidase_M36 PF02128.15 EGE05447.1 - 3.5e-156 520.0 0.4 4.4e-156 519.7 0.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGE05447.1 - 2.1e-16 59.5 3.1 2.1e-16 59.5 3.1 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGE05447.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Colicin_M PF14859.6 EGE05447.1 - 0.025 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Colicin M UQ_con PF00179.26 EGE05449.1 - 2.7e-38 130.8 0.0 3.3e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGE05449.1 - 0.025 14.8 0.3 0.049 13.9 0.3 1.6 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 EGE05449.1 - 0.031 14.0 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Bax1-I PF01027.20 EGE05450.1 - 1.8e-55 188.0 28.3 2.1e-55 187.8 28.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SLATT_4 PF18186.1 EGE05450.1 - 2.2 7.9 3.9 1.1 8.9 0.8 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Aa_trans PF01490.18 EGE05451.1 - 1.2e-92 310.8 17.3 1.8e-92 310.2 17.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.10 EGE05451.1 - 0.1 10.8 3.4 0.17 10.1 3.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Glyco_hydro_75 PF07335.11 EGE05452.1 - 1.4e-61 207.6 0.2 1.7e-61 207.3 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 EMC1_C PF07774.13 EGE05453.1 - 1.4e-77 260.1 0.0 2.5e-77 259.4 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 EGE05453.1 - 5.5e-06 26.0 2.7 1.1 9.3 0.0 4.7 4 0 0 4 4 4 3 PQQ enzyme repeat AT_hook PF02178.19 EGE05454.1 - 0.0012 18.4 67.5 0.052 13.4 1.7 6.9 7 0 0 7 7 7 5 AT hook motif CRAL_TRIO PF00650.20 EGE05455.1 - 2.8e-24 85.6 0.0 3.9e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE05455.1 - 0.00094 19.3 0.2 0.0033 17.6 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain SNase PF00565.17 EGE05456.1 - 5.8e-80 264.8 0.1 1.8e-25 89.5 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGE05456.1 - 1.2e-24 86.6 0.0 3.5e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EGE05456.1 - 0.00025 20.4 0.0 0.00044 19.6 0.0 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EGE05456.1 - 0.0094 16.4 0.9 0.048 14.1 0.2 2.6 3 0 0 3 3 3 1 Agenet domain DUF3297 PF11730.8 EGE05456.1 - 0.033 14.1 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) Fungal_trans PF04082.18 EGE05457.1 - 9.2e-26 90.5 0.3 1.7e-25 89.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05457.1 - 2.1e-05 24.5 8.2 2.1e-05 24.5 8.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.6 EGE05457.1 - 0.21 9.5 1.6 0.32 8.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sod_Cu PF00080.20 EGE05458.1 - 4.1e-31 108.1 2.3 5.2e-31 107.7 2.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TAL_FSA PF00923.19 EGE05459.1 - 6.3e-95 317.8 0.1 7.1e-95 317.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Beach PF02138.18 EGE05460.1 - 1.5e-118 395.2 0.0 2.5e-118 394.5 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGE05460.1 - 7.6e-10 38.8 0.1 7.6e-10 38.8 0.1 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGE05460.1 - 5e-08 33.5 4.2 0.009 16.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-C2H2_2 PF12756.7 EGE05461.1 - 6.2e-35 119.6 20.4 1.6e-30 105.4 3.0 3.8 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGE05461.1 - 9.7e-12 44.9 11.1 2.2e-05 24.6 3.1 4.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGE05461.1 - 1.9e-06 28.1 13.9 8.6e-06 26.0 3.5 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type DUF2024 PF09630.10 EGE05461.1 - 0.033 14.1 4.9 0.067 13.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Cytochrome-c551 PF10643.9 EGE05461.1 - 0.04 13.5 0.3 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 zf-C2H2 PF00096.26 EGE05461.1 - 0.13 12.8 0.3 0.13 12.8 0.3 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type Cytochrome_CBB3 PF13442.6 EGE05461.1 - 0.18 12.1 3.1 16 5.9 0.1 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III zf-C2H2_4 PF13894.6 EGE05461.1 - 1.9 9.5 25.1 2.4 9.2 0.2 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger Abhydrolase_3 PF07859.13 EGE05463.1 - 2.2e-06 27.7 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE05463.1 - 0.00099 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGE05463.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGE05463.1 - 0.12 12.0 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Pkinase PF00069.25 EGE05464.1 - 1.9e-62 211.1 0.0 2.5e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05464.1 - 2.4e-22 79.5 0.0 6.9e-22 78.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE05464.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE05464.1 - 0.0015 17.6 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGE05464.1 - 0.0027 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGE05464.1 - 0.041 12.9 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy_2 PF13532.6 EGE05465.1 - 6e-30 104.9 0.0 2.9e-29 102.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC_2 PF13913.6 EGE05467.1 - 0.0014 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EGE05467.1 - 0.0072 17.1 0.3 0.017 15.9 0.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.12 EGE05467.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding JAKMIP_CC3 PF16034.5 EGE05467.1 - 0.04 13.9 3.9 0.12 12.3 3.9 1.8 1 0 0 1 1 1 0 JAKMIP CC3 domain zf-C2H2 PF00096.26 EGE05467.1 - 0.058 13.9 0.4 0.12 12.8 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type FAD_binding_3 PF01494.19 EGE05468.1 - 3.5e-14 52.8 1.4 2.9e-07 30.1 0.0 3.2 2 1 1 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.24 EGE05468.1 - 0.00014 21.1 0.1 0.00072 18.7 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGE05468.1 - 0.0002 21.1 3.0 0.024 14.2 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE05468.1 - 0.00038 19.8 0.1 0.001 18.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Imm_superinfect PF14373.6 EGE05468.1 - 0.0052 16.7 1.4 0.0052 16.7 1.4 2.5 3 0 0 3 3 3 1 Superinfection immunity protein HI0933_like PF03486.14 EGE05468.1 - 0.092 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1279 PF06916.13 EGE05468.1 - 0.87 10.2 2.7 28 5.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) MFS_1 PF07690.16 EGE05470.1 - 2.6e-43 148.3 41.5 2.6e-43 148.3 41.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05470.1 - 2.7e-10 39.7 13.1 2.7e-10 39.7 13.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGE05470.1 - 0.0021 16.6 6.2 0.0021 16.6 6.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EGE05472.1 - 1.8e-14 53.5 0.0 2.8e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05472.1 - 3.4e-08 33.5 9.3 6.6e-08 32.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EGE05473.1 - 7e-67 225.7 0.0 1.6e-66 224.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGE05473.1 - 8.3e-49 165.9 0.0 1.7e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGE05473.1 - 2.4e-45 155.1 0.0 3.8e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EGE05473.1 - 3e-39 135.4 0.1 7.5e-39 134.1 0.1 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGE05473.1 - 2.9e-28 98.3 0.1 2.9e-28 98.3 0.1 2.3 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EGE05473.1 - 1.6e-19 70.5 0.0 4.9e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGE05473.1 - 3.3e-15 56.5 0.0 8.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EGE05473.1 - 1.2e-14 54.8 0.0 4.2e-14 53.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE05473.1 - 1.2e-12 48.3 0.0 3.4e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE05473.1 - 1.4e-10 41.3 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05473.1 - 5.1e-09 36.1 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGE05473.1 - 1.8e-08 34.1 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05473.1 - 2e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 EGE05473.1 - 3.9e-06 26.4 0.0 8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 EGE05473.1 - 3.8e-05 23.9 0.3 0.0001 22.6 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGE05473.1 - 8.9e-05 22.0 0.5 0.00066 19.1 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.6 EGE05473.1 - 0.0057 17.7 0.0 0.027 15.5 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGE05473.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 EGE05473.1 - 0.024 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 EGE05473.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SAT PF16073.5 EGE05473.1 - 0.061 13.1 1.9 4.8 6.8 0.3 2.4 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis AA_permease_2 PF13520.6 EGE05474.1 - 1.2e-57 195.7 47.7 1.5e-57 195.4 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE05474.1 - 2.2e-20 72.7 40.3 3e-20 72.3 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Plasmod_dom_1 PF09715.10 EGE05474.1 - 0.18 11.9 1.0 0.66 10.1 1.0 2.1 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF3237 PF11578.8 EGE05476.1 - 1.6e-07 31.3 0.1 2.4e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) DLH PF01738.18 EGE05477.1 - 1.4e-14 54.1 0.0 1.7e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Cu-oxidase_3 PF07732.15 EGE05478.1 - 4.7e-44 149.2 0.1 4.1e-43 146.2 0.2 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE05478.1 - 5.9e-39 132.9 3.8 1e-35 122.4 0.1 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE05478.1 - 7.3e-32 110.7 0.1 2.4e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Atx10homo_assoc PF09759.9 EGE05478.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain LysM PF01476.20 EGE05480.1 - 1.7e-14 53.6 0.0 1.5e-07 31.3 0.0 3.2 3 0 0 3 3 3 3 LysM domain MFS_1 PF07690.16 EGE05481.1 - 1.9e-23 83.0 51.1 1.9e-16 60.0 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cutinase PF01083.22 EGE05482.1 - 4e-35 121.4 0.0 4.7e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EGE05482.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EGE05482.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) UPF0565 PF10561.9 EGE05482.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RED_N PF07808.13 EGE05483.1 - 3.6e-08 33.3 5.3 3.6e-08 33.3 5.3 2.9 3 1 0 3 3 3 1 RED-like protein N-terminal region Glyco_hydro_cc PF11790.8 EGE05484.1 - 5.8e-60 202.8 1.0 7e-60 202.6 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core P_proprotein PF01483.20 EGE05485.1 - 7.7e-26 89.9 3.0 1.2e-25 89.3 0.7 2.4 3 0 0 3 3 3 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 EGE05485.1 - 4.6e-23 81.9 2.1 1.4e-20 73.7 0.9 2.3 1 1 1 2 2 2 2 Subtilase family DUF3328 PF11807.8 EGE05487.1 - 5.2e-26 91.8 5.7 6.9e-26 91.4 5.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EGE05488.1 - 1.3e-15 57.8 0.6 1.2e-14 54.6 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_2 PF00891.18 EGE05489.1 - 1.6e-28 99.5 0.0 2.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGE05489.1 - 2.6e-06 27.3 0.0 4.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE05489.1 - 7.1e-05 23.4 0.3 0.0031 18.2 0.0 3.1 4 0 0 4 4 4 1 Methyltransferase domain CheR PF01739.18 EGE05489.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 EGE05489.1 - 0.017 14.7 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EGE05489.1 - 0.15 12.8 0.0 0.73 10.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.31 EGE05490.1 - 3.5e-37 126.3 6.7 1e-12 48.1 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE05490.1 - 5.7e-28 96.9 3.8 1.1e-13 51.2 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGE05490.1 - 1.2e-05 25.1 0.1 0.0022 17.8 0.0 3.1 3 1 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGE05490.1 - 0.00047 20.5 7.1 0.37 11.2 0.1 3.8 3 1 0 3 3 3 2 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EGE05490.1 - 0.003 17.6 0.0 0.71 10.0 0.0 2.8 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EGE05490.1 - 0.0058 16.8 2.7 0.03 14.5 0.2 3.2 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 FAD_binding_4 PF01565.23 EGE05491.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE05491.1 - 0.00089 19.3 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like PsbT PF01405.17 EGE05491.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre T protein adh_short PF00106.25 EGE05492.1 - 2.2e-46 157.8 0.1 2.8e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05492.1 - 5.4e-33 114.5 0.1 7.1e-33 114.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05492.1 - 1e-09 38.6 0.1 1.5e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGE05492.1 - 7.4e-06 25.5 0.0 1.8e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGE05492.1 - 0.00026 20.9 0.2 0.00059 19.8 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE05492.1 - 0.027 14.0 0.1 2.6 7.5 0.1 2.2 2 0 0 2 2 2 0 NmrA-like family AA_permease PF00324.21 EGE05493.1 - 7.4e-119 397.5 37.9 8.4e-119 397.3 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05493.1 - 1.6e-29 103.0 42.6 1.8e-29 102.8 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease HTH_23 PF13384.6 EGE05494.1 - 1e-06 28.3 0.2 2.7e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EGE05494.1 - 4.9e-05 22.9 0.1 0.00065 19.3 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 EGE05494.1 - 5.5e-05 22.8 0.6 5.5e-05 22.8 0.6 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Mucin PF01456.17 EGE05494.1 - 0.00013 22.0 6.3 0.00016 21.7 6.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein HTH_32 PF13565.6 EGE05494.1 - 0.00015 22.3 3.7 0.0038 17.8 0.1 2.8 1 1 1 3 3 3 1 Homeodomain-like domain HTH_7 PF02796.15 EGE05494.1 - 0.0012 18.9 0.3 0.26 11.4 0.1 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_31 PF13560.6 EGE05494.1 - 0.0034 17.7 0.7 0.011 16.0 0.7 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain GerE PF00196.19 EGE05494.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_28 PF13518.6 EGE05494.1 - 0.0084 16.2 0.3 0.0084 16.2 0.3 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EGE05494.1 - 0.028 13.9 0.1 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_1 PF01527.20 EGE05494.1 - 0.068 13.5 0.9 0.21 11.9 0.1 2.2 2 1 0 2 2 2 0 Transposase HTH_3 PF01381.22 EGE05494.1 - 0.1 12.7 0.7 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix TMEM154 PF15102.6 EGE05494.1 - 4.1 7.3 10.0 6.2 6.7 10.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3439 PF11921.8 EGE05494.1 - 6.6 6.7 10.8 13 5.7 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) KGG PF10685.9 EGE05495.1 - 3.1e-25 87.6 15.7 5.1e-10 39.3 0.5 3.3 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Aminotran_5 PF00266.19 EGE05496.1 - 7.2e-16 58.1 0.0 1.1e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V EutN_CcmL PF03319.13 EGE05496.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome UNC-93 PF05978.16 EGE05497.1 - 3.5e-05 23.5 2.4 3.5e-05 23.5 2.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 CcmE PF03100.15 EGE05497.1 - 0.032 14.2 0.4 0.076 13.0 0.4 1.6 1 0 0 1 1 1 0 CcmE WD40 PF00400.32 EGE05498.1 - 7.8e-57 187.9 12.1 7.8e-11 42.4 0.6 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05498.1 - 5.9e-24 84.2 0.0 3.7e-05 23.9 0.0 6.0 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE05498.1 - 2.5e-08 33.2 0.2 0.06 12.3 0.0 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGE05498.1 - 3e-08 32.8 0.2 0.084 11.5 0.0 4.4 2 2 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGE05498.1 - 1.5e-05 24.5 0.0 0.0002 20.8 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain PD40 PF07676.12 EGE05498.1 - 6.7e-05 22.7 2.0 0.9 9.6 0.1 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EGE05498.1 - 0.0077 15.3 0.1 0.29 10.2 0.0 2.9 1 1 1 3 3 3 1 Protein of unknown function (DUF1513) Nbas_N PF15492.6 EGE05498.1 - 0.021 14.1 0.5 6.3 6.0 0.0 3.4 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EGE05498.1 - 0.042 12.2 0.0 0.14 10.5 0.0 1.7 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz RAB3GAP2_N PF14655.6 EGE05498.1 - 0.15 11.3 0.0 0.59 9.3 0.0 2.0 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 EGE05498.1 - 0.19 10.6 0.2 13 4.6 0.1 2.8 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Exo_endo_phos PF03372.23 EGE05499.1 - 3.3e-13 49.7 0.1 5.1e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thi4 PF01946.17 EGE05500.1 - 3.3e-108 360.3 0.0 4e-108 360.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGE05500.1 - 6.5e-07 29.3 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE05500.1 - 1.3e-05 25.3 0.1 7.9e-05 22.8 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGE05500.1 - 0.00019 20.6 0.3 0.00034 19.8 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGE05500.1 - 0.0018 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE05500.1 - 0.0034 17.4 0.1 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGE05500.1 - 0.077 11.8 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EGE05500.1 - 0.088 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EGE05500.1 - 0.12 11.4 0.3 0.3 10.1 0.3 1.6 2 0 0 2 2 2 0 FAD binding domain ACC_epsilon PF13822.6 EGE05501.1 - 2.1 9.1 8.6 1.8 9.3 1.1 2.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ppx-GppA PF02541.16 EGE05502.1 - 5.4e-40 137.6 0.0 4e-39 134.8 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Proteasome PF00227.26 EGE05503.1 - 1.2e-46 158.6 0.1 1.5e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pil1 PF13805.6 EGE05504.1 - 3.1e-84 282.6 1.2 3.8e-84 282.3 1.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 SWI-SNF_Ssr4 PF08549.10 EGE05505.1 - 5e-230 766.0 26.2 2.1e-227 757.3 26.2 2.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DUF4832 PF16116.5 EGE05505.1 - 0.14 12.0 0.3 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4832) MRPL52 PF18699.1 EGE05505.1 - 0.63 10.3 2.5 0.63 10.3 0.2 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 RNA_pol_Rpb2_6 PF00562.28 EGE05506.1 - 1.4e-74 251.5 0.0 2e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGE05506.1 - 6e-39 133.7 0.0 9.1e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGE05506.1 - 1.3e-27 95.8 0.0 2.7e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGE05506.1 - 1.5e-26 93.3 0.0 2.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGE05506.1 - 3.8e-25 87.7 0.0 9.1e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain PS-DH PF14765.6 EGE05508.1 - 7.6e-62 209.2 0.0 1.2e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGE05508.1 - 5e-58 196.0 0.0 1.6e-57 194.3 0.0 2.0 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 EGE05508.1 - 1.5e-57 195.1 0.0 2.8e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGE05508.1 - 1e-48 166.5 0.2 1.1e-37 130.3 0.0 3.0 3 0 0 3 3 3 2 Acyl transferase domain ADH_zinc_N PF00107.26 EGE05508.1 - 4.4e-17 62.3 0.0 1.3e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE05508.1 - 1.1e-16 62.1 0.0 1.2e-15 58.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGE05508.1 - 3.2e-15 56.7 0.0 8e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EGE05508.1 - 7.5e-13 48.4 0.5 1.8e-09 37.3 0.0 3.3 4 0 0 4 4 4 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.22 EGE05508.1 - 2.9e-12 46.6 0.1 8.2e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_23 PF13489.6 EGE05508.1 - 6.6e-11 42.3 0.0 1.6e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05508.1 - 1.3e-09 38.0 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE05508.1 - 3.1e-09 37.4 0.0 1e-08 35.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE05508.1 - 7.8e-09 36.1 0.0 2.8e-08 34.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGE05508.1 - 0.00014 22.2 0.0 0.0003 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGE05508.1 - 0.00014 21.7 0.0 0.00048 20.0 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EGE05508.1 - 0.00021 20.7 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGE05508.1 - 0.00097 18.9 0.0 0.012 15.3 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Rsm22 PF09243.10 EGE05508.1 - 0.039 13.2 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 Arf PF00025.21 EGE05509.1 - 1.6e-43 148.1 0.0 1.9e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGE05509.1 - 5.5e-20 71.6 0.0 6.2e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE05509.1 - 3.5e-15 56.3 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGE05509.1 - 2.9e-08 33.8 0.0 4.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGE05509.1 - 1.9e-06 27.5 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGE05509.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGE05509.1 - 7.2e-05 22.1 0.0 0.00058 19.1 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1_Xtn PF16897.5 EGE05509.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EGE05509.1 - 0.0024 17.9 0.1 0.035 14.2 0.2 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 EGE05509.1 - 0.022 14.3 0.2 0.061 12.9 0.0 1.7 3 0 0 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGE05509.1 - 0.081 12.8 0.1 9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF1979 PF09322.10 EGE05509.1 - 0.17 11.8 1.6 3.5 7.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RCR PF12273.8 EGE05510.1 - 3.3e-13 50.3 24.2 3.3e-13 50.3 24.2 2.0 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 EGE05510.1 - 5.2e-05 23.1 2.2 6.2e-05 22.8 2.2 1.3 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2868 PF11067.8 EGE05510.1 - 0.0014 18.3 0.4 0.0014 18.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) WBP-1 PF11669.8 EGE05510.1 - 0.041 14.5 0.8 0.061 14.0 0.8 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Corona_S2 PF01601.16 EGE05511.1 - 2.1 6.7 16.8 2.9 6.3 16.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MFS_1 PF07690.16 EGE05512.1 - 4.4e-14 52.2 53.4 6.7e-11 41.7 35.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_4 PF06779.14 EGE05512.1 - 0.00037 19.9 19.8 0.00056 19.3 19.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CwfJ_C_1 PF04677.15 EGE05514.1 - 1.6e-24 86.1 0.0 2.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGE05514.1 - 3.9e-16 59.7 0.3 9.6e-16 58.5 0.3 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Toxin_38 PF14866.6 EGE05514.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Potassium channel toxin DRIM PF07539.12 EGE05515.1 - 8e-185 615.7 12.2 3e-184 613.8 0.7 4.1 4 0 0 4 4 4 2 Down-regulated in metastasis HEAT PF02985.22 EGE05515.1 - 0.00018 21.5 2.6 0.73 10.3 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat KAR PF15222.6 EGE05515.1 - 0.00056 20.2 0.2 0.0025 18.1 0.1 2.2 2 0 0 2 2 2 1 Kidney androgen-regulated Wap1 PF16997.5 EGE05515.1 - 0.019 14.1 0.0 3.4 6.7 0.0 3.5 3 0 0 3 3 3 0 Wap1 domain HTH_37 PF13744.6 EGE05515.1 - 3.4 7.7 5.2 64 3.6 0.0 4.3 4 0 0 4 4 4 0 Helix-turn-helix domain zf-DNL PF05180.12 EGE05516.1 - 1.2e-27 95.6 0.4 2.3e-27 94.7 0.4 1.5 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EGE05516.1 - 0.0097 15.7 1.1 1.4 8.8 0.2 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 EGE05516.1 - 0.018 14.8 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.13 EGE05516.1 - 0.077 13.1 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 EGE05516.1 - 0.23 11.4 2.1 0.51 10.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain E7 PF00527.18 EGE05516.1 - 0.59 10.4 3.4 1.2 9.4 1.6 2.4 2 1 0 2 2 2 0 E7 protein, Early protein Cullin PF00888.22 EGE05517.1 - 6.6e-200 665.8 7.9 6.6e-200 665.8 7.9 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGE05517.1 - 1.9e-27 95.1 1.2 6.8e-27 93.3 0.8 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1737 PF08410.10 EGE05517.1 - 0.11 12.3 0.1 0.32 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) HEPN_DZIP3 PF18738.1 EGE05517.1 - 0.18 11.5 1.4 18 5.1 0.0 2.9 2 1 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Kinesin_assoc PF16183.5 EGE05517.1 - 1.2 9.3 7.3 4.1 7.5 0.1 3.2 3 0 0 3 3 3 0 Kinesin-associated SLD5_C PF16922.5 EGE05518.1 - 1.2e-10 41.4 0.2 2.1e-10 40.6 0.2 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGE05518.1 - 3.4e-09 37.1 0.7 4.9e-09 36.6 0.7 1.2 1 0 0 1 1 1 1 GINS complex protein DUF4899 PF16240.5 EGE05518.1 - 0.019 14.2 0.1 0.028 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) Rhodanese PF00581.20 EGE05519.1 - 5.8e-14 52.5 0.1 1.3e-13 51.4 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Iso_dh PF00180.20 EGE05521.1 - 6.6e-53 180.1 0.0 1e-52 179.4 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_pol_phi PF04931.13 EGE05522.1 - 2.1e-238 793.3 10.5 2.6e-238 793.0 10.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi TINF2_N PF14973.6 EGE05522.1 - 0.09 13.1 1.6 8.4 6.7 0.1 2.6 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus TPT PF03151.16 EGE05523.1 - 1.8e-22 80.1 18.4 2.3e-22 79.7 18.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGE05523.1 - 1.3e-05 25.4 39.5 0.00075 19.7 17.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family AD PF09793.9 EGE05524.1 - 8.9e-26 89.9 0.0 2.1e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain RRM_1 PF00076.22 EGE05525.1 - 4.6e-18 64.8 0.0 7.6e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 EGE05525.1 - 5.3 6.9 21.4 9.3 6.1 21.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 6PGD PF00393.19 EGE05526.1 - 7.6e-128 425.9 0.0 9.4e-128 425.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGE05526.1 - 7.4e-50 169.2 0.0 1.1e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGE05526.1 - 0.053 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EGE05526.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Esterase_phd PF10503.9 EGE05526.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_C15 PF01470.17 EGE05527.1 - 5.7e-13 49.5 0.0 2.1e-06 28.1 0.0 2.3 2 1 0 2 2 2 2 Pyroglutamyl peptidase CENP-B_dimeris PF09026.10 EGE05528.1 - 0.035 14.5 3.4 0.04 14.3 3.4 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EGE05528.1 - 0.46 10.2 4.9 0.57 9.9 4.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_III_psi PF03603.13 EGE05529.1 - 0.033 14.4 0.0 0.073 13.3 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase III psi subunit AA_permease PF00324.21 EGE05532.1 - 1.7e-113 379.7 37.6 2.2e-113 379.4 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05532.1 - 2.4e-28 99.1 40.2 2.9e-28 98.9 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 EGE05533.1 - 2.3e-26 92.9 0.6 1e-21 77.9 0.4 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EGE05533.1 - 9e-08 32.6 0.0 4.1e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE05533.1 - 3.5e-07 30.4 0.1 7.1e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE05533.1 - 6.5e-07 29.8 0.0 0.0011 19.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE05533.1 - 5.3e-05 23.3 0.0 0.15 12.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EGE05533.1 - 0.00018 21.8 0.0 0.8 10.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat AP_endonuc_2 PF01261.24 EGE05534.1 - 7.1e-30 104.0 0.0 1.5e-29 102.9 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel SPT2 PF08243.11 EGE05534.1 - 0.0096 16.4 4.6 0.0096 16.4 4.6 2.0 2 0 0 2 2 2 1 SPT2 chromatin protein GOLD_2 PF13897.6 EGE05534.1 - 0.23 11.9 0.8 1.1 9.8 0.6 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Mad3_BUB1_I PF08311.12 EGE05535.1 - 3.7e-44 149.7 0.4 7.8e-44 148.6 0.1 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EGE05535.1 - 3.1e-16 59.3 0.0 3.1e-15 56.1 0.0 2.7 3 1 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EGE05535.1 - 6.7e-12 45.3 0.0 1.2e-10 41.2 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05535.1 - 0.00081 18.7 0.0 0.0029 16.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EGE05535.1 - 0.0038 17.3 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein APH PF01636.23 EGE05535.1 - 0.075 12.9 0.1 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF4379 PF14311.6 EGE05536.1 - 0.012 15.9 3.5 0.033 14.6 3.5 1.7 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Med13_C PF06333.12 EGE05536.1 - 0.55 9.4 3.7 0.94 8.7 3.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SRP-alpha_N PF04086.13 EGE05536.1 - 3.9 7.3 14.3 4.7 7.1 1.5 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RNA_polI_A34 PF08208.11 EGE05536.1 - 6.8 6.7 22.7 0.6 10.2 3.9 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Hexokinase_1 PF00349.21 EGE05537.1 - 1.9e-58 197.6 0.0 2.6e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGE05537.1 - 1.3e-44 152.5 0.0 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF3237 PF11578.8 EGE05539.1 - 2.7e-10 40.3 0.0 3.2e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_N PF08240.12 EGE05540.1 - 8.6e-21 73.9 1.7 1.6e-20 73.0 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE05540.1 - 1.9e-05 24.6 0.0 4.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 EGE05541.1 - 1.3e-11 44.1 0.3 2.3e-11 43.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05541.1 - 2.3e-09 37.2 9.5 4.7e-09 36.2 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mur_ligase_M PF08245.12 EGE05542.1 - 1.3e-09 38.3 0.4 1.4e-07 31.7 0.1 2.6 2 1 0 2 2 2 2 Mur ligase middle domain TPR_7 PF13176.6 EGE05543.1 - 3.2e-11 42.4 0.2 0.0055 16.7 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05543.1 - 1.9e-09 37.7 3.0 0.00028 21.1 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE05543.1 - 3e-09 36.3 0.9 0.08 13.1 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE05543.1 - 1e-08 35.3 0.2 1.8 9.6 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE05543.1 - 4.7e-08 33.4 0.0 0.0076 16.7 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05543.1 - 2.1e-06 27.5 5.0 2.3 8.7 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE05543.1 - 3.3e-06 26.7 0.9 7.3e-06 25.6 0.1 1.9 2 1 0 2 2 2 1 MalT-like TPR region TPR_1 PF00515.28 EGE05543.1 - 0.00016 21.3 0.5 0.67 9.9 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGE05543.1 - 0.0013 18.5 0.0 0.27 11.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 EGE05543.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE05543.1 - 0.012 16.0 0.0 0.044 14.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ANAPC3 PF12895.7 EGE05543.1 - 0.055 13.7 0.2 2.4 8.4 0.0 3.4 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 EGE05543.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PPR PF01535.20 EGE05543.1 - 0.34 11.3 4.8 45 4.6 0.0 4.7 5 0 0 5 5 5 0 PPR repeat zf-UBR PF02207.20 EGE05544.1 - 6.9e-16 58.2 19.4 6.9e-16 58.2 19.4 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EGE05544.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 EGE05544.1 - 0.016 15.5 1.0 0.016 15.5 1.0 4.1 3 0 0 3 3 3 0 Ring finger domain ELL PF10390.9 EGE05544.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL UCR_UQCRX_QCR9 PF05365.12 EGE05545.1 - 1.7e-26 91.9 1.2 1.9e-26 91.7 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 EGE05546.1 - 3.2e-14 52.5 2.6 5.8e-14 51.6 2.6 1.4 1 0 0 1 1 1 1 Mago binding SprA-related PF12118.8 EGE05546.1 - 0.0054 15.9 2.1 0.0065 15.6 2.1 1.1 1 0 0 1 1 1 1 SprA-related family Amino_oxidase PF01593.24 EGE05547.1 - 1.2e-18 67.6 0.0 1.6e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase zf-CCCH_2 PF14608.6 EGE05548.1 - 1.9e-11 44.0 54.0 1.5e-06 28.5 10.1 5.5 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EGE05548.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.22 EGE05549.1 - 2.3e-74 250.9 0.0 3.4e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGE05549.1 - 3.4e-34 118.4 0.1 2.4e-33 115.7 0.2 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGE05549.1 - 9.1e-05 23.2 0.0 0.0015 19.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 EGE05550.1 - 1.3e-59 202.1 0.0 5e-43 147.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2-Hacid_dh_C PF02826.19 EGE05552.1 - 2.1e-53 180.3 0.0 3.3e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE05552.1 - 3.1e-37 127.2 0.1 4.9e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EGE05552.1 - 0.0013 18.1 2.5 0.006 15.9 2.5 2.0 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EGE05552.1 - 0.003 18.0 0.0 0.0085 16.6 0.0 1.8 1 0 0 1 1 1 1 XdhC Rossmann domain ACT PF01842.25 EGE05552.1 - 0.01 15.6 0.6 0.079 12.8 0.0 2.7 3 0 0 3 3 3 0 ACT domain F420_oxidored PF03807.17 EGE05552.1 - 0.043 14.4 0.4 14 6.4 0.0 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fe-ADH PF00465.19 EGE05553.1 - 1.3e-103 346.6 0.0 1.8e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGE05553.1 - 3.3e-16 59.8 0.0 5.6e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EGE05553.1 - 0.0088 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Ank_2 PF12796.7 EGE05554.1 - 1.4e-72 240.3 14.8 3.7e-15 56.3 0.3 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE05554.1 - 3.1e-65 215.8 13.8 9.3e-13 48.4 0.1 8.6 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE05554.1 - 1.3e-54 175.8 12.0 1.9e-05 24.7 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank PF00023.30 EGE05554.1 - 6e-51 168.8 15.8 1.6e-06 28.3 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.6 EGE05554.1 - 1.5e-45 152.6 16.4 1.3e-07 31.8 0.0 9.6 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ig_GlcNase PF18368.1 EGE05555.1 - 1.2e-36 125.0 0.6 9.3e-36 122.2 0.3 2.4 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EGE05555.1 - 4.9e-10 40.0 0.1 7.2e-09 36.3 0.0 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EGE05555.1 - 1.3e-07 31.6 0.2 3.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Mannosidase_ig PF17786.1 EGE05555.1 - 3.1e-05 24.5 0.1 0.00055 20.5 0.0 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EGE05555.1 - 0.027 14.2 0.1 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 Ig-fold domain DNA_circ_N PF07157.12 EGE05555.1 - 0.044 14.2 0.0 17 5.9 0.0 3.2 3 0 0 3 3 3 0 DNA circularisation protein N-terminus CARDB PF07705.11 EGE05555.1 - 0.074 13.3 0.2 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 CARDB Glyco_hydro_2_C PF02836.17 EGE05555.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Kin17_mid PF10357.9 EGE05556.1 - 7.4e-48 161.6 1.6 1.6e-47 160.5 1.6 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EGE05556.1 - 2.3e-05 24.6 0.9 5.5e-05 23.4 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGE05556.1 - 0.00046 20.4 0.3 0.00046 20.4 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGE05556.1 - 0.0081 16.5 2.9 0.013 15.8 0.4 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Hydin_ADK PF17213.3 EGE05556.1 - 4 7.7 5.9 1.8 8.8 3.5 1.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Glyoxalase PF00903.25 EGE05557.1 - 2.3e-37 128.0 0.1 3.7e-18 65.9 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGE05557.1 - 4.3e-16 59.1 0.0 3e-06 27.5 0.0 3.8 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGE05557.1 - 3.6e-07 30.9 0.0 0.0023 18.7 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EGE05557.1 - 1.1e-06 28.9 0.0 0.02 15.0 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EGE05557.1 - 0.023 14.6 0.1 4.7 7.2 0.0 3.6 4 1 0 4 4 4 0 Glyoxalase-like domain CppA_N PF14506.6 EGE05557.1 - 0.05 13.7 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 CppA N-terminal Apolipoprotein PF01442.18 EGE05559.1 - 0.0042 17.0 1.4 0.0056 16.6 0.6 1.5 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain FCH PF00611.23 EGE05559.1 - 0.11 12.9 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Spc7 PF08317.11 EGE05559.1 - 0.11 11.3 1.1 0.65 8.8 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Arrestin_C PF02752.22 EGE05560.1 - 4.9e-18 65.9 0.0 9.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGE05560.1 - 7.7e-10 39.0 0.0 3.6e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Hexapep PF00132.24 EGE05561.1 - 1.8e-06 27.5 11.2 4.9e-05 22.9 2.9 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGE05561.1 - 0.0063 16.2 0.4 0.0063 16.2 0.4 2.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase An_peroxidase PF03098.15 EGE05562.1 - 6.8e-42 143.7 0.0 3e-28 98.7 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EGE05562.1 - 2.7e-08 33.0 0.0 1.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 EGE05563.1 - 7e-99 330.8 0.0 8.9e-99 330.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_61 PF03443.14 EGE05564.1 - 0.0098 15.8 0.1 0.045 13.7 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EGE05564.1 - 0.058 14.1 0.0 0.17 12.5 0.0 1.8 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading MARVEL PF01284.23 EGE05565.1 - 0.00012 22.1 12.4 0.00023 21.2 12.4 1.4 1 1 0 1 1 1 1 Membrane-associating domain TMEM156 PF15106.6 EGE05565.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family PGA2 PF07543.12 EGE05566.1 - 2.6e-44 150.6 1.4 3e-44 150.4 1.4 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CCD PF07860.11 EGE05566.1 - 0.0089 16.1 0.2 0.041 13.9 0.0 1.9 1 1 1 2 2 2 1 WisP family C-Terminal Region CENP-S PF15630.6 EGE05567.1 - 1.4e-30 105.5 0.0 1.7e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGE05567.1 - 1.3e-10 41.4 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EGE05567.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 1 0 1 1 1 0 Bromodomain associated MMS1_N PF10433.9 EGE05568.1 - 2.5e-123 412.3 0.0 6.6e-123 410.9 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGE05568.1 - 1.4e-61 208.6 0.1 5.6e-61 206.6 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region PQQ_3 PF13570.6 EGE05568.1 - 0.68 10.5 2.7 8.3 7.0 0.2 4.2 5 0 0 5 5 5 0 PQQ-like domain NAD_binding_2 PF03446.15 EGE05569.1 - 1.8e-35 122.4 0.0 2.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGE05569.1 - 8.4e-27 93.8 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGE05569.1 - 1.5e-06 28.6 0.0 4.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGE05569.1 - 0.00024 20.5 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGE05569.1 - 0.0012 19.6 0.0 0.0025 18.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_membrane PF00664.23 EGE05570.1 - 4.1e-86 289.0 39.5 1.7e-44 152.5 16.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE05570.1 - 2.3e-63 212.7 0.0 4e-33 114.8 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE05570.1 - 3.7e-16 59.3 3.9 3.7e-06 26.6 0.7 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EGE05570.1 - 1.8e-08 34.5 0.1 0.0016 18.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 EGE05570.1 - 6.6e-08 33.1 0.4 0.0063 16.9 0.1 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EGE05570.1 - 1.1e-07 31.9 1.3 0.001 18.9 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGE05570.1 - 2.3e-07 31.1 4.7 0.0085 16.4 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_21 PF13304.6 EGE05570.1 - 3.5e-07 30.3 0.0 0.033 14.0 0.0 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGE05570.1 - 3.9e-07 30.1 0.0 0.0086 16.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EGE05570.1 - 1.1e-06 29.1 0.4 0.17 12.3 0.0 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGE05570.1 - 5.1e-06 26.3 0.1 0.073 12.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EGE05570.1 - 2.7e-05 23.2 0.3 0.066 12.0 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EGE05570.1 - 3.8e-05 23.3 0.9 0.016 15.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGE05570.1 - 0.00019 22.0 0.1 0.48 11.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGE05570.1 - 0.0002 21.0 1.6 0.14 11.7 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EGE05570.1 - 0.0004 20.4 0.0 2.4 8.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EGE05570.1 - 0.0014 19.2 12.8 0.0063 17.0 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_7 PF12775.7 EGE05570.1 - 0.0034 16.9 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGE05570.1 - 0.0036 16.6 0.0 0.57 9.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.18 EGE05570.1 - 0.0038 17.0 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 EGE05570.1 - 0.0043 17.2 1.2 1.7 9.0 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EGE05570.1 - 0.005 17.1 0.0 3.8 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EGE05570.1 - 0.0082 15.8 0.3 2.3 7.8 0.2 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EGE05570.1 - 0.013 15.9 0.0 5.1 7.5 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EGE05570.1 - 0.02 14.6 0.0 8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGE05570.1 - 0.025 14.2 0.0 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGE05570.1 - 0.039 14.1 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGE05570.1 - 0.067 13.2 0.2 4.7 7.3 0.0 3.4 4 0 0 4 4 3 0 AAA domain Pterin_4a PF01329.19 EGE05573.1 - 5.1e-08 33.0 0.0 6.9e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Pterin 4 alpha carbinolamine dehydratase WSC PF01822.19 EGE05574.1 - 7.6e-36 122.2 31.4 5.2e-18 65.0 11.5 2.7 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 EGE05574.1 - 2.1e-22 79.9 0.2 4.1e-22 79.0 0.2 1.4 1 0 0 1 1 1 1 Peroxidase Flg_new PF09479.10 EGE05574.1 - 0.025 14.8 3.6 0.19 11.9 0.1 3.5 4 0 0 4 4 4 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) PSI_PSAK PF01241.18 EGE05574.1 - 0.05 13.6 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Photosystem I psaG / psaK Glyco_trans_2_3 PF13632.6 EGE05575.1 - 1.5e-48 165.4 0.4 1.5e-48 165.4 0.4 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Spt20 PF12090.8 EGE05575.1 - 5.1 6.6 7.6 25 4.4 6.6 2.0 2 0 0 2 2 2 0 Spt20 family Glyco_hydro_16 PF00722.21 EGE05576.1 - 5.7e-18 65.0 0.0 4.5e-17 62.1 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 WSC PF01822.19 EGE05577.1 - 2e-47 159.3 45.1 5.6e-18 64.9 10.5 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 EGE05577.1 - 1.8e-24 86.2 0.0 9.2e-24 83.9 0.0 2.1 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGE05577.1 - 8.1e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 EGE05577.1 - 0.045 13.7 0.0 0.45 10.6 0.0 2.8 2 0 0 2 2 2 0 Kelch motif wnt PF00110.19 EGE05577.1 - 5.7 6.4 10.9 4.9 6.7 0.8 3.4 2 1 1 3 3 3 0 wnt family MFS_1 PF07690.16 EGE05578.1 - 4.2e-14 52.3 70.4 1.2e-09 37.6 19.0 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EGE05578.1 - 0.00019 20.0 27.4 0.00027 19.5 27.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HNH_2 PF13391.6 EGE05579.1 - 0.043 14.0 0.3 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease Ank_2 PF12796.7 EGE05580.1 - 8.5e-11 42.3 0.0 3.6e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGE05580.1 - 3.5e-08 33.5 0.1 0.66 10.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGE05580.1 - 3.3e-07 30.7 0.0 0.0045 17.5 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) vWA-TerF-like PF10138.9 EGE05580.1 - 7.1e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus WD40_3 PF15911.5 EGE05580.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF3040 PF11239.8 EGE05580.1 - 0.33 11.3 1.5 0.7 10.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SseC PF04888.12 EGE05580.1 - 0.38 10.3 10.2 0.65 9.5 10.2 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4635 PF15466.6 EGE05580.1 - 0.41 10.2 2.6 0.18 11.3 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Peptidase_C3 PF00548.20 EGE05582.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) FAD_binding_4 PF01565.23 EGE05583.1 - 1.7e-24 86.1 4.4 3.2e-24 85.2 4.4 1.4 1 0 0 1 1 1 1 FAD binding domain Transgly_assoc PF04226.13 EGE05583.1 - 6.4 7.1 13.5 0.048 13.9 5.0 1.8 2 0 0 2 2 2 0 Transglycosylase associated protein p450 PF00067.22 EGE05584.1 - 2.9e-38 131.8 0.0 4.3e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EGE05585.1 - 6.5e-25 87.8 43.4 7.9e-25 87.5 40.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 EGE05585.1 - 0.011 14.4 3.2 0.19 10.2 2.2 2.3 1 1 1 2 2 2 0 Ferroportin1 (FPN1) Zn_clus PF00172.18 EGE05586.1 - 4.5e-07 29.9 11.4 4.5e-07 29.9 11.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S41 PF03572.18 EGE05586.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S41 Fungal_trans PF04082.18 EGE05587.1 - 5e-16 58.5 0.0 7.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05587.1 - 2.1e-08 34.1 8.5 4.4e-08 33.1 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 EGE05587.1 - 0.0026 16.3 0.0 0.0038 15.8 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Trp_DMAT PF11991.8 EGE05588.1 - 1.9e-107 359.8 0.0 2.2e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase AMP-binding PF00501.28 EGE05589.1 - 2e-138 461.6 0.0 3.2e-73 246.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EGE05589.1 - 5.3e-86 289.1 0.0 3.5e-48 164.4 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE05589.1 - 9.7e-28 96.3 0.1 6.2e-09 36.1 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE05589.1 - 1.8e-10 41.7 0.1 0.00032 21.6 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Methyltransf_2 PF00891.18 EGE05590.1 - 7.7e-27 94.0 0.0 1.1e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGE05590.1 - 0.00094 19.1 0.1 0.0027 17.7 0.0 1.7 2 0 0 2 2 2 1 Dimerisation domain Rrf2 PF02082.20 EGE05590.1 - 0.18 12.2 0.0 0.46 10.9 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator FANCI_S4 PF14678.6 EGE05590.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 DIT1_PvcA PF05141.12 EGE05591.1 - 1.9e-90 303.1 0.0 2.7e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 EGE05591.1 - 2.9e-23 82.2 0.0 4.7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 EGE05591.1 - 1.9e-13 49.8 0.0 2.2e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Transferase family PP-binding PF00550.25 EGE05591.1 - 1.2e-07 31.9 0.0 3.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 EGE05592.1 - 1.1e-17 64.1 51.3 7.2e-12 44.9 29.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3435 PF11917.8 EGE05594.1 - 2.4e-18 66.3 0.2 2.9e-18 66.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) 2-Hacid_dh_C PF02826.19 EGE05595.1 - 7.5e-55 185.0 0.0 9.7e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE05595.1 - 1.4e-18 66.8 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGE05595.1 - 8.3e-08 32.6 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGE05595.1 - 0.00065 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGE05595.1 - 0.037 13.7 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 EGE05595.1 - 0.053 14.0 0.0 0.096 13.2 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 EGE05595.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SKN1 PF03935.15 EGE05596.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Phosducin PF02114.16 EGE05598.1 - 3.1e-14 52.6 0.0 1.1e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 Phosducin BET PF17035.5 EGE05599.1 - 8.8e-07 29.0 0.2 1.7e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 EGE05600.1 - 5.6e-52 175.2 2.0 9.1e-52 174.5 2.0 1.3 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 EGE05600.1 - 0.00046 20.4 0.1 0.00062 20.0 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain WH1 PF00568.23 EGE05600.1 - 0.0013 18.7 0.4 0.0078 16.1 0.4 2.0 1 1 0 1 1 1 1 WH1 domain LAP1C PF05609.12 EGE05600.1 - 0.52 9.3 9.2 0.62 9.1 9.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tom5 PF10642.9 EGE05600.1 - 6.2 6.9 5.3 0.91 9.6 0.5 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Apolipoprotein PF01442.18 EGE05601.1 - 0.00073 19.5 4.5 0.0021 17.9 4.5 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DivIC PF04977.15 EGE05601.1 - 0.044 13.5 0.1 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator SMBP PF16785.5 EGE05601.1 - 0.17 12.1 2.5 0.48 10.7 2.5 1.7 1 0 0 1 1 1 0 Small metal-binding protein DivIVA PF05103.13 EGE05601.1 - 0.24 11.5 3.3 0.69 10.0 3.3 1.8 1 0 0 1 1 1 0 DivIVA protein YtxH PF12732.7 EGE05601.1 - 0.57 10.8 2.3 1.7 9.2 2.3 1.9 1 0 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 EGE05601.1 - 2.1 9.0 6.1 1.9 9.2 4.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_transf_15 PF01793.16 EGE05602.1 - 2.5e-95 319.5 13.9 8.1e-95 317.8 13.9 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.29 EGE05603.1 - 4.8e-28 97.7 1.7 9.5e-14 51.8 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EGE05603.1 - 1.2e-12 48.2 4.3 1.7e-07 31.6 0.1 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EGE05603.1 - 7.6e-08 32.7 5.9 0.0023 18.3 0.1 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 EGE05603.1 - 0.00051 20.3 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PBP_N PF17093.5 EGE05603.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus Spt20 PF12090.8 EGE05603.1 - 0.008 15.8 1.9 0.043 13.4 1.4 2.0 2 0 0 2 2 2 1 Spt20 family PH_13 PF16652.5 EGE05603.1 - 0.1 12.4 0.2 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 EGE05603.1 - 0.29 11.5 2.0 3.2 8.2 0.1 2.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region DOT1 PF08123.13 EGE05604.1 - 1.3e-76 256.7 0.0 2e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGE05604.1 - 0.0011 19.7 0.0 0.0064 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 EGE05604.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_31 PF13847.6 EGE05604.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 EGE05604.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family ATG16 PF08614.11 EGE05605.1 - 1e-53 182.5 18.9 1.2e-53 182.4 18.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CCDC144C PF14915.6 EGE05605.1 - 0.0038 16.4 11.2 0.0038 16.4 11.2 1.4 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region Golgin_A5 PF09787.9 EGE05605.1 - 0.01 15.4 9.0 0.013 15.0 9.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EGE05605.1 - 0.022 14.9 13.3 0.069 13.2 4.5 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sec2p PF06428.11 EGE05605.1 - 0.043 13.8 10.7 0.076 13.0 9.7 2.0 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3496 PF12001.8 EGE05605.1 - 0.12 12.8 3.5 0.11 12.9 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) HAUS-augmin3 PF14932.6 EGE05605.1 - 0.14 11.8 8.6 0.14 11.7 7.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 EGE05605.1 - 0.27 10.1 15.0 0.13 11.1 12.7 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.6 EGE05605.1 - 0.32 10.7 12.1 0.099 12.4 9.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SecD-TM1 PF13721.6 EGE05605.1 - 0.39 11.2 1.8 0.69 10.4 1.1 1.9 1 1 1 2 2 2 0 SecD export protein N-terminal TM region DUF948 PF06103.11 EGE05605.1 - 0.87 9.9 3.3 13 6.2 3.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 EGE05605.1 - 0.98 8.7 7.0 1.2 8.4 7.0 1.1 1 0 0 1 1 1 0 FAM76 protein Fez1 PF06818.15 EGE05605.1 - 1.2 9.6 13.1 2.2 8.7 6.8 2.1 1 1 1 2 2 2 0 Fez1 COG2 PF06148.11 EGE05605.1 - 1.2 9.2 7.2 0.78 9.8 1.3 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 EGE05605.1 - 1.5 8.1 11.5 2.4 7.4 11.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 EGE05605.1 - 1.9 8.4 7.2 1.7 8.5 0.5 2.6 2 1 1 3 3 3 0 Sec34-like family APG6_N PF17675.1 EGE05605.1 - 2.8 8.5 17.7 0.82 10.2 12.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4472 PF14739.6 EGE05605.1 - 3.3 8.5 12.6 0.81 10.4 6.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) GvpG PF05120.12 EGE05605.1 - 3.8 7.6 9.0 0.16 12.0 1.9 2.3 2 1 1 3 3 2 0 Gas vesicle protein G Exonuc_VII_L PF02601.15 EGE05605.1 - 3.9 7.0 11.7 1.8 8.0 9.1 1.5 1 1 0 2 2 2 0 Exonuclease VII, large subunit YabA PF06156.13 EGE05605.1 - 5 7.8 11.1 0.68 10.6 2.2 2.5 2 1 1 3 3 3 0 Initiation control protein YabA Ras PF00071.22 EGE05606.1 - 5.8e-56 188.6 0.2 6.9e-56 188.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE05606.1 - 1.1e-31 109.5 0.0 1.7e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE05606.1 - 9.8e-14 51.2 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE05606.1 - 8.9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGE05606.1 - 3e-07 30.0 0.1 3.8e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGE05606.1 - 1.3e-06 28.1 0.0 4.1e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE05606.1 - 8.3e-05 22.5 0.2 0.0031 17.5 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EGE05606.1 - 0.0028 17.4 0.1 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGE05606.1 - 0.0042 16.7 0.0 0.014 15.0 0.0 1.7 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGE05606.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EGE05606.1 - 0.0085 15.9 0.3 0.24 11.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGE05606.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EGE05606.1 - 0.0091 15.3 0.5 0.047 13.0 0.0 2.2 3 0 0 3 3 3 1 Septin AAA_16 PF13191.6 EGE05606.1 - 0.011 16.2 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EGE05606.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGE05606.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGE05606.1 - 0.023 14.4 0.3 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGE05606.1 - 0.06 13.3 1.2 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EGE05606.1 - 0.062 13.2 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase TniB PF05621.11 EGE05606.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EGE05606.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGE05606.1 - 0.18 12.3 0.1 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 ABC transporter EamA PF00892.20 EGE05607.1 - 7.2e-11 42.4 36.8 6.6e-08 32.8 4.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EGE05607.1 - 1.9e-07 30.9 11.3 1.9e-07 30.9 11.3 1.9 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 EGE05607.1 - 1.2e-05 24.7 0.5 1.2e-05 24.7 0.5 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 EGE05607.1 - 0.00035 20.3 0.9 0.00035 20.3 0.9 4.1 5 2 1 6 6 6 1 Protein of unknown function (DUF3955) TPT PF03151.16 EGE05607.1 - 0.029 13.7 8.6 0.091 12.1 0.7 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.11 EGE05607.1 - 0.057 12.6 15.2 0.01 15.1 11.7 1.5 2 0 0 2 2 2 0 UAA transporter family DUF2981 PF11200.8 EGE05607.1 - 0.059 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Spb1_C PF07780.12 EGE05608.1 - 1e-85 286.7 17.3 1e-85 286.7 17.3 2.7 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGE05608.1 - 1.2e-55 188.3 0.0 2.3e-55 187.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGE05608.1 - 1.1e-24 87.0 18.4 3.2e-20 72.6 0.1 5.6 4 2 1 6 6 6 2 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EGE05608.1 - 0.0019 18.1 0.0 0.0059 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGE05608.1 - 0.021 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F KCT2 PF17818.1 EGE05608.1 - 1.6 8.8 12.5 5.6 7.1 1.6 2.5 2 0 0 2 2 2 0 Keratinocyte-associated gene product PcfJ PF14284.6 EGE05608.1 - 5 7.0 7.3 0.49 10.3 1.5 2.3 2 0 0 2 2 2 0 PcfJ-like protein EF-hand_4 PF12763.7 EGE05611.1 - 0.00087 19.2 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 EGE05612.1 - 7.5e-70 235.3 0.0 9.3e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05612.1 - 6.3e-33 114.1 0.0 8.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGE05612.1 - 1.9e-09 38.1 2.5 4.9e-09 36.8 2.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGE05612.1 - 1e-05 24.7 0.1 1.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGE05612.1 - 0.043 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EGE05612.1 - 0.073 12.7 0.1 0.83 9.2 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_ligase_A_M PF01068.21 EGE05613.1 - 5.3e-48 163.4 0.0 4.5e-47 160.3 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGE05613.1 - 3.9e-41 141.3 0.0 1e-40 139.9 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EGE05613.1 - 2.2e-21 76.1 0.2 4.7e-14 52.5 0.2 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EGE05613.1 - 8.5e-19 68.4 0.0 1.9e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EGE05613.1 - 3.9e-17 62.7 0.0 1.2e-16 61.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EGE05613.1 - 6.9e-09 36.0 0.2 1.7e-05 25.1 0.1 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGE05613.1 - 1.5e-08 34.8 2.0 0.00039 20.7 0.0 2.8 2 1 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EGE05613.1 - 0.00066 19.5 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EGE05613.1 - 0.019 14.9 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain Fungal_trans PF04082.18 EGE05614.1 - 2.8e-45 154.4 0.0 5.6e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05614.1 - 4.6e-08 33.1 9.1 9e-08 32.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EGE05614.1 - 0.0076 16.1 4.7 0.019 14.9 4.7 1.7 1 0 0 1 1 1 1 PHD-finger MnmE_helical PF12631.7 EGE05614.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain Tmemb_cc2 PF10267.9 EGE05614.1 - 0.16 11.1 0.3 0.26 10.4 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Metallophos PF00149.28 EGE05615.1 - 1.1e-31 111.0 0.0 4.6e-22 79.5 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGE05615.1 - 0.088 13.3 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 EGE05616.1 - 0.0086 16.1 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 DUF4646 PF15496.6 EGE05617.1 - 3.5e-19 69.6 0.0 5.6e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.13 EGE05618.1 - 6e-138 460.2 21.0 6.9e-138 459.9 21.0 1.0 1 0 0 1 1 1 1 ALG3 protein CRPA PF05745.11 EGE05618.1 - 0.46 10.5 2.6 6.7 6.7 0.3 3.1 2 1 1 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) eIF-1a PF01176.19 EGE05619.1 - 1e-19 70.1 0.1 1.5e-19 69.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.25 EGE05620.1 - 3.1e-60 203.8 0.0 6e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05620.1 - 3.9e-35 121.4 0.0 6.9e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EGE05620.1 - 1.3e-29 102.1 12.0 1.6e-15 57.0 2.7 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EGE05620.1 - 1.8e-20 72.5 27.8 8.4e-12 44.8 9.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EGE05620.1 - 1.5e-14 54.4 1.5 8.3e-14 52.0 1.7 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGE05620.1 - 0.028 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like C2 PF00168.30 EGE05620.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 C2 domain TFIIA PF03153.13 EGE05620.1 - 0.3 11.0 34.0 3.4 7.6 28.4 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit zf-RING_9 PF13901.6 EGE05620.1 - 2.7 7.9 22.2 1.6 8.7 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon MdcE PF06833.11 EGE05621.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase gamma subunit (MdcE) TFCD_C PF12612.8 EGE05622.1 - 4.6e-32 111.4 0.0 1e-31 110.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGE05622.1 - 5.9e-06 26.1 0.3 1.4 9.4 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EGE05622.1 - 0.00051 20.4 1.6 0.51 10.8 0.1 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EGE05622.1 - 0.0036 17.8 0.9 1.8 9.1 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGE05622.1 - 0.15 12.7 0.0 2.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.22 EGE05623.1 - 3.9e-27 93.9 1.0 2.7e-12 46.3 0.5 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE05623.1 - 0.00015 21.3 0.0 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE05623.1 - 0.011 15.5 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4523 PF15023.6 EGE05623.1 - 0.019 14.8 0.1 0.05 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 EGE05623.1 - 1 9.5 3.9 12 6.1 0.1 3.3 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 EGE05624.1 - 6.7e-71 238.2 0.9 9.7e-71 237.7 0.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 EGE05624.1 - 0.0035 17.4 1.6 0.017 15.2 0.5 2.2 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 EGE05624.1 - 0.049 13.1 0.3 0.077 12.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) DUF3919 PF13057.6 EGE05624.1 - 0.061 12.9 0.6 0.09 12.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) TPR_14 PF13428.6 EGE05625.1 - 2e-15 56.2 12.0 1.4 10.0 0.0 11.7 9 2 3 12 12 12 3 Tetratricopeptide repeat Suf PF05843.14 EGE05625.1 - 3e-11 43.9 10.8 0.0076 16.3 0.1 5.9 3 1 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGE05625.1 - 1.7e-08 34.8 0.0 0.56 10.8 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE05625.1 - 5e-08 32.5 4.4 0.33 11.3 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE05625.1 - 9.7e-07 29.0 4.2 29 5.0 0.0 7.3 6 1 0 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGE05625.1 - 1.6e-06 28.1 12.4 0.88 9.6 0.1 7.2 6 2 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EGE05625.1 - 1.9e-06 27.3 4.4 0.00042 19.6 0.2 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE05625.1 - 1.1e-05 25.2 12.9 1.1 9.6 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE05625.1 - 0.00049 20.3 3.1 1.3 9.6 0.0 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE05625.1 - 0.0024 17.6 0.0 5 7.1 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.16 EGE05625.1 - 0.0037 17.2 3.0 2.1 8.4 0.1 5.4 5 0 0 5 5 4 1 HAT (Half-A-TPR) repeat TPR_11 PF13414.6 EGE05625.1 - 0.041 13.6 0.1 0.52 10.0 0.1 3.1 3 1 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 EGE05625.1 - 0.16 11.9 9.1 61 3.7 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 EGE05625.1 - 0.26 11.6 0.8 1.4e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 PPR repeat NRDE-2 PF08424.10 EGE05625.1 - 1.3 8.1 15.8 0.086 11.9 0.5 6.0 3 3 2 5 5 5 0 NRDE-2, necessary for RNA interference Sec7 PF01369.20 EGE05626.1 - 2.4e-60 203.4 0.0 3.8e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGE05626.1 - 3.7e-22 78.9 0.2 5.1e-20 72.0 0.0 3.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EGE05626.1 - 0.0019 17.9 0.8 0.0068 16.1 0.8 2.0 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 RhoGEF PF00621.20 EGE05628.1 - 2.8e-19 70.0 0.0 5.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 EGE05628.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 EGE05628.1 - 0.057 13.6 0.0 0.85 9.8 0.0 2.6 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 OmpH PF03938.14 EGE05628.1 - 4.7 7.5 5.5 1.5 9.2 1.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EGE05628.1 - 8.4 5.9 8.4 18 4.8 8.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_3 PF01171.20 EGE05629.1 - 8.4e-43 146.2 0.0 3.3e-42 144.3 0.0 2.0 1 1 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EGE05629.1 - 0.019 14.1 0.0 0.091 11.9 0.0 2.0 2 0 0 2 2 2 0 NAD synthase Mito_carr PF00153.27 EGE05630.1 - 4.6e-45 151.5 3.2 8.8e-20 70.4 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.8 EGE05631.1 - 7.9e-56 188.6 0.0 1.7e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EGE05631.1 - 4.3e-21 74.8 18.3 9e-05 23.2 0.3 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05631.1 - 7e-05 23.0 0.4 0.21 11.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE05631.1 - 0.00048 18.9 2.5 0.015 14.0 0.1 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGE05631.1 - 0.15 11.0 0.9 2.9 6.7 0.4 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Pkinase PF00069.25 EGE05632.1 - 2.3e-47 161.6 0.0 1.2e-46 159.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05632.1 - 1.3e-21 77.1 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE05632.1 - 0.0027 17.7 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE05632.1 - 0.0072 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE05632.1 - 0.022 13.7 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGE05632.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L11 PF00298.19 EGE05633.1 - 3.9e-27 94.5 0.1 6.1e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EGE05633.1 - 3.5e-13 49.2 0.6 6.3e-13 48.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 EGE05634.1 - 2.3e-52 177.1 0.0 4.7e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EGE05634.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain LZ_Tnp_IS481 PF13011.6 EGE05635.1 - 0.062 13.8 0.3 0.24 12.0 0.0 1.9 1 1 1 2 2 2 0 leucine-zipper of insertion element IS481 AbiEi_4 PF13338.6 EGE05635.1 - 0.07 13.3 0.4 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin BP28CT PF08146.12 EGE05635.1 - 0.093 12.6 0.0 0.099 12.5 0.0 1.1 1 0 0 1 1 1 0 BP28CT (NUC211) domain Acetyltransf_1 PF00583.25 EGE05636.1 - 0.0027 17.9 0.0 0.0042 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF5368 PF17336.2 EGE05636.1 - 0.006 16.7 1.6 0.01 16.0 1.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5368) Acetyltransf_13 PF13880.6 EGE05636.1 - 0.047 13.7 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TALPID3 PF15324.6 EGE05637.1 - 0.031 12.0 2.2 0.026 12.2 2.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target AAA_6 PF12774.7 EGE05638.1 - 3.4e-124 414.1 0.0 1.7e-123 411.8 0.0 2.3 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGE05638.1 - 5.5e-116 387.9 2.9 5.5e-116 387.9 2.9 4.1 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EGE05638.1 - 4.7e-113 378.8 6.1 4.7e-113 378.8 6.1 4.1 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 EGE05638.1 - 3.9e-66 223.0 0.0 1.6e-65 221.0 0.0 2.2 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGE05638.1 - 1.9e-41 141.6 0.0 1.8e-36 125.4 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EGE05638.1 - 3.2e-39 134.9 6.8 5.9e-39 134.0 6.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 EGE05638.1 - 1e-37 129.4 22.5 7.9e-27 93.8 0.0 5.5 4 2 1 5 5 4 2 ATP-binding dynein motor region AAA_5 PF07728.14 EGE05638.1 - 1.4e-32 112.5 0.5 8.4e-11 42.0 0.0 6.5 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EGE05638.1 - 1.5e-28 99.3 0.4 5.4e-27 94.3 0.0 3.9 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EGE05638.1 - 6.2e-27 94.4 0.0 1.6e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGE05638.1 - 1.2e-15 58.0 1.0 0.0079 16.5 0.0 7.4 7 0 0 7 7 6 2 AAA domain AAA PF00004.29 EGE05638.1 - 2.2e-14 54.0 0.0 0.00039 20.9 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGE05638.1 - 7.7e-10 39.4 0.7 0.076 13.6 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EGE05638.1 - 5e-09 36.5 6.2 0.095 12.9 0.0 5.7 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 EGE05638.1 - 5.9e-09 36.5 7.2 1.2 9.5 0.0 8.0 8 0 0 8 8 6 2 AAA ATPase domain AAA_lid_1 PF17857.1 EGE05638.1 - 8.2e-07 29.2 0.4 9.2e-05 22.6 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain T2SSE PF00437.20 EGE05638.1 - 4.3e-05 22.7 0.0 0.033 13.2 0.0 2.9 2 0 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGE05638.1 - 4.5e-05 22.9 1.0 0.64 9.4 0.0 4.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGE05638.1 - 5.3e-05 23.8 1.6 2.4 8.7 0.0 5.2 4 0 0 4 4 3 1 ABC transporter AAA_14 PF13173.6 EGE05638.1 - 0.00018 21.5 0.0 1.8 8.6 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGE05638.1 - 0.00043 20.0 0.1 2.2 8.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGE05638.1 - 0.00062 19.5 0.7 37 4.0 0.0 4.8 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 EGE05638.1 - 0.0018 18.6 2.4 0.27 11.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EGE05638.1 - 0.0024 17.8 0.0 12 5.8 0.0 4.1 4 0 0 4 4 4 0 RsgA GTPase AAA_25 PF13481.6 EGE05638.1 - 0.0027 17.3 0.0 0.31 10.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGE05638.1 - 0.0029 17.3 0.5 11 5.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EGE05638.1 - 0.0033 17.2 0.5 0.58 9.9 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EGE05638.1 - 0.0046 16.4 2.8 2 7.7 0.0 4.1 4 0 0 4 4 3 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EGE05638.1 - 0.0087 15.4 0.2 3.6 6.8 0.2 3.7 3 0 0 3 3 3 1 Zeta toxin Rad17 PF03215.15 EGE05638.1 - 0.0099 15.8 0.2 6.3 6.7 0.0 4.3 5 0 0 5 5 4 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGE05638.1 - 0.013 15.9 0.1 32 5.0 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Dynein_AAA_lid PF17852.1 EGE05638.1 - 0.1 12.7 0.1 19 5.4 0.0 3.0 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain MEDS PF14417.6 EGE05638.1 - 0.14 11.9 1.8 0.38 10.6 0.1 2.7 2 0 0 2 2 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain PduV-EutP PF10662.9 EGE05638.1 - 0.34 10.7 1.7 11 5.7 0.1 4.0 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 EGE05638.1 - 1.2 9.5 6.7 1.4e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 AAA domain Phage_GP20 PF06810.11 EGE05638.1 - 2.1 8.1 20.1 4.7 7.0 9.6 4.1 3 0 0 3 3 2 0 Phage minor structural protein GP20 DUF4482 PF14818.6 EGE05638.1 - 2.2 9.1 18.2 21 5.9 9.8 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) ERM PF00769.19 EGE05638.1 - 3 7.6 28.2 1.9 8.2 14.6 3.3 3 0 0 3 3 2 0 Ezrin/radixin/moesin family Ribonuclease_3 PF00636.26 EGE05639.1 - 1.2e-40 138.4 0.0 1.5e-19 70.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EGE05639.1 - 2.4e-23 82.7 0.0 3.1e-12 46.8 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EGE05639.1 - 7.6e-21 74.1 0.2 1.1e-18 67.1 0.1 3.0 1 1 1 2 2 2 1 Dicer dimerisation domain ResIII PF04851.15 EGE05639.1 - 2.4e-16 60.2 0.3 6.5e-16 58.8 0.3 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGE05639.1 - 1.1e-13 51.5 0.2 5.5e-13 49.2 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE05639.1 - 6.5e-10 39.1 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EGE05639.1 - 0.0028 18.3 0.1 0.83 10.4 0.0 2.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif TrbI_Ftype PF09677.10 EGE05639.1 - 0.077 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) AAA_22 PF13401.6 EGE05639.1 - 0.083 13.2 0.1 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.12 EGE05640.1 - 4.5e-108 361.2 5.4 5e-108 361.0 5.4 1.0 1 0 0 1 1 1 1 TAP42-like family DUF725 PF05267.12 EGE05640.1 - 0.058 13.4 0.5 0.13 12.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Uteroglobin PF01099.17 EGE05640.1 - 6.5 7.2 6.0 23 5.4 0.0 3.1 3 0 0 3 3 3 0 Uteroglobin family Lipase_GDSL PF00657.22 EGE05641.1 - 4.8e-13 49.5 0.0 6.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EGE05641.1 - 5.8e-09 36.6 0.0 6.7e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PRP21_like_P PF12230.8 EGE05641.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Porphobil_deam PF01379.20 EGE05642.1 - 9.4e-74 247.3 0.1 1.3e-73 246.9 0.1 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGE05642.1 - 9e-19 67.6 0.5 1.6e-18 66.9 0.5 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1534 PF07551.11 EGE05642.1 - 0.16 11.7 0.1 1.9 8.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1534) Lon_C PF05362.13 EGE05643.1 - 7.2e-69 231.4 0.3 1.4e-68 230.4 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EGE05643.1 - 1e-24 87.6 0.7 1.7e-24 86.8 0.1 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EGE05643.1 - 4.6e-24 85.3 0.0 3.2e-23 82.6 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGE05643.1 - 1.1e-07 32.0 0.0 3.7e-07 30.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGE05643.1 - 2.4e-07 30.6 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EGE05643.1 - 2e-06 28.3 0.1 1.1e-05 26.0 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EGE05643.1 - 7.8e-06 25.7 0.0 2.2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EGE05643.1 - 2.1e-05 23.9 0.0 4.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 EGE05643.1 - 6.7e-05 22.8 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGE05643.1 - 0.00033 20.4 0.1 0.0012 18.6 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGE05643.1 - 0.00067 19.8 0.0 0.004 17.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGE05643.1 - 0.0011 19.3 0.2 0.01 16.1 0.0 2.7 2 1 0 2 2 1 1 AAA domain Birna_VP4 PF01768.16 EGE05643.1 - 0.0053 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_33 PF13671.6 EGE05643.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGE05643.1 - 0.013 15.9 0.0 0.055 13.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EGE05643.1 - 0.014 15.5 0.0 0.048 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGE05643.1 - 0.015 15.2 0.1 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 EGE05643.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGE05643.1 - 0.023 14.1 0.1 0.059 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGE05643.1 - 0.026 15.0 0.1 0.087 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGE05643.1 - 0.037 14.0 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 EGE05643.1 - 0.04 13.3 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 EGE05643.1 - 0.041 14.2 0.6 0.21 11.9 0.3 2.4 2 1 0 2 2 1 0 AAA domain PhoH PF02562.16 EGE05643.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.11 EGE05643.1 - 0.045 12.7 0.1 0.35 9.7 0.0 2.0 1 1 0 2 2 2 0 PrkA AAA domain TsaE PF02367.17 EGE05643.1 - 0.05 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGE05643.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGE05643.1 - 0.074 12.8 0.1 0.074 12.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE05643.1 - 0.093 12.4 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGE05643.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGE05643.1 - 0.12 11.5 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 EGE05643.1 - 0.14 11.5 0.1 0.29 10.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EGE05643.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.1 1 1 1 2 2 1 0 AAA domain ABC_tran PF00005.27 EGE05643.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Laps PF10169.9 EGE05643.1 - 1.1 9.8 3.5 4 8.0 0.0 2.5 1 1 1 2 2 2 0 Learning-associated protein Ribosomal_L23 PF00276.20 EGE05644.1 - 5.2e-10 39.5 0.0 8.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.22 EGE05645.1 - 1.6e-40 138.7 0.3 7e-28 97.5 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EGE05645.1 - 5.6e-32 109.8 0.0 1.3e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EGE05645.1 - 2.7e-05 24.2 0.0 0.11 12.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE05645.1 - 0.00017 21.0 0.0 0.0073 15.7 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SGT1 PF07093.11 EGE05645.1 - 0.22 9.9 5.5 2.3 6.5 5.9 1.9 2 0 0 2 2 2 0 SGT1 protein Chs7 PF12271.8 EGE05646.1 - 4.3e-124 413.5 15.5 5e-124 413.3 15.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 EGE05646.1 - 9.4 6.6 9.5 2.1 8.7 3.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Ribosomal_L27A PF00828.19 EGE05647.1 - 2.8e-30 105.6 0.4 4.9e-30 104.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EGE05650.1 - 2.8e-46 158.0 0.0 3.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05650.1 - 1.6e-26 93.1 0.0 4.6e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE05650.1 - 0.0034 16.2 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SelP_N PF04592.14 EGE05650.1 - 0.36 10.2 18.6 0.6 9.5 18.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 EGE05650.1 - 0.53 9.4 2.9 0.79 8.9 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.16 EGE05650.1 - 8 5.7 9.0 14 4.9 9.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sec62 PF03839.16 EGE05651.1 - 1.5 8.3 5.9 1.6 8.1 5.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 EGE05651.1 - 2 7.1 9.9 2.2 7.0 9.9 1.0 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EGE05651.1 - 2.5 6.3 21.1 3.1 6.0 21.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family MDM10 PF12519.8 EGE05651.1 - 3.5 6.4 7.4 3.6 6.4 7.4 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 MCM_bind PF09739.9 EGE05651.1 - 4.5 5.6 9.6 4.8 5.5 9.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CAF-1_p150 PF11600.8 EGE05651.1 - 4.6 6.9 27.1 6.1 6.5 27.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Paf1 PF03985.13 EGE05651.1 - 6.4 5.7 16.7 7.8 5.4 16.7 1.0 1 0 0 1 1 1 0 Paf1 RXLR PF16810.5 EGE05651.1 - 6.4 7.2 10.8 10 6.5 10.8 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity NPR3 PF03666.13 EGE05651.1 - 7.8 5.2 13.7 8 5.1 13.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SH3_1 PF00018.28 EGE05652.1 - 2e-05 24.1 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE05652.1 - 0.0073 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 EGE05652.1 - 0.035 13.9 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain RCC1_2 PF13540.6 EGE05653.1 - 1.7e-14 53.2 7.7 4.8e-08 32.6 0.0 4.6 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EGE05653.1 - 4.2e-08 32.9 0.1 8.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE05653.1 - 0.079 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 F-box domain RCC1 PF00415.18 EGE05653.1 - 0.11 13.1 1.0 4.6 7.9 0.0 3.8 4 1 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat PQ-loop PF04193.14 EGE05654.1 - 4.9e-37 125.5 12.0 2.5e-18 65.6 1.7 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EGE05654.1 - 0.001 19.0 6.5 0.016 15.2 0.2 2.9 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange 7TM_GPCR_Srsx PF10320.9 EGE05654.1 - 0.013 14.9 1.2 0.023 14.1 1.2 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx DUF2627 PF11118.8 EGE05654.1 - 0.061 13.9 0.3 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Aminotran_1_2 PF00155.21 EGE05655.1 - 1.4e-63 215.3 0.0 2e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 EGE05655.1 - 0.0024 18.3 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 188 Beta_elim_lyase PF01212.21 EGE05655.1 - 0.0048 16.2 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase AMP-binding PF00501.28 EGE05656.1 - 2.2e-36 125.4 0.0 4e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGE05656.1 - 2e-09 37.2 1.4 7.5e-09 35.4 0.2 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_M16_C PF05193.21 EGE05657.1 - 1.7e-49 168.3 0.0 3.7e-49 167.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGE05657.1 - 3.3e-40 137.5 0.0 4.3e-39 133.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 EGE05657.1 - 0.18 11.9 1.0 0.57 10.3 1.0 1.8 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Abhydrolase_2 PF02230.16 EGE05658.1 - 1.6e-26 93.5 0.0 9.9e-18 64.7 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGE05658.1 - 0.00039 19.8 0.0 0.01 15.1 0.0 2.3 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGE05658.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EGE05658.1 - 0.013 15.2 0.0 0.041 13.5 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGE05658.1 - 0.023 15.3 0.4 0.037 14.6 0.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGE05658.1 - 0.038 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom22 PF04281.13 EGE05659.1 - 4.1e-52 175.7 1.0 4.7e-52 175.5 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 EGE05660.1 - 1.9e-43 148.0 0.0 4e-43 146.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4449 PF14613.6 EGE05661.1 - 7.6e-64 214.7 0.7 7.6e-64 214.7 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Peptidase_M35 PF02102.15 EGE05662.1 - 2.9e-70 236.9 0.0 3.6e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGE05662.1 - 2e-32 112.7 0.1 3.5e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase vWA-TerF-like PF10138.9 EGE05665.1 - 4.5e-07 30.2 0.0 6.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.6 EGE05665.1 - 0.0037 17.6 28.8 0.0037 17.6 28.8 2.4 2 0 0 2 2 2 1 Proline-rich VWA PF00092.28 EGE05665.1 - 0.071 13.4 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain PhoLip_ATPase_C PF16212.5 EGE05666.1 - 4.4e-70 236.3 21.7 4.4e-70 236.3 21.7 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGE05666.1 - 6.7e-25 86.6 3.6 1.2e-23 82.6 0.3 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGE05666.1 - 3.7e-16 60.0 0.1 7.7e-06 26.3 0.0 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE05666.1 - 2.3e-12 46.9 0.0 1.3e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGE05666.1 - 2.4e-11 43.5 0.2 1.1e-10 41.4 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGE05666.1 - 0.003 17.4 0.0 0.0096 15.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 EGE05667.1 - 3.8e-20 71.5 2.5 8.2e-20 70.4 2.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGE05667.1 - 0.0016 18.3 0.4 0.004 17.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain PGP_phosphatase PF09419.10 EGE05668.1 - 4.8e-52 176.0 0.0 5.6e-52 175.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EGE05668.1 - 3.9e-06 26.8 0.1 6.9e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGE05668.1 - 0.00045 20.6 0.1 0.62 10.3 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase TPP_enzyme_M PF00205.22 EGE05668.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.6 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, central domain LSM PF01423.22 EGE05669.1 - 3.9e-15 55.3 0.2 5.2e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE05669.1 - 0.097 12.8 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.9 EGE05670.1 - 4.8e-18 65.9 4.5 4.8e-18 65.9 4.5 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.14 EGE05671.1 - 1.6e-28 99.5 12.3 1e-14 54.6 5.3 2.5 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA SRP_TPR_like PF17004.5 EGE05672.1 - 8.6e-19 67.7 0.4 2.6e-18 66.1 0.1 2.0 3 0 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 EGE05672.1 - 4.8e-14 52.5 6.8 4.8e-14 52.5 6.8 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EGE05672.1 - 1.8e-08 34.7 2.2 0.0032 17.9 0.0 4.9 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE05672.1 - 0.0011 19.1 4.2 19 5.5 0.0 5.9 5 2 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGE05672.1 - 0.002 18.4 0.5 3.2 8.1 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE05672.1 - 0.022 14.9 0.7 0.22 11.7 0.0 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGE05672.1 - 0.022 14.4 0.3 0.97 9.1 0.0 3.1 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) AF0941-like PF14591.6 EGE05672.1 - 0.026 15.1 1.4 0.12 13.0 0.2 2.4 2 0 0 2 2 2 0 AF0941-like TPR_2 PF07719.17 EGE05672.1 - 0.059 13.5 7.6 23 5.4 1.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGE05672.1 - 0.72 9.8 2.1 1.5e+02 2.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat VCX_VCY PF15231.6 EGE05672.1 - 0.92 10.2 7.7 1.9 9.2 7.7 1.5 1 0 0 1 1 1 0 Variable charge X/Y family Homeobox_KN PF05920.11 EGE05673.1 - 3.5e-20 71.6 0.8 7e-20 70.7 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGE05673.1 - 0.00012 21.8 0.2 0.00023 21.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain FAD_binding_1 PF00667.20 EGE05674.1 - 9.1e-45 152.9 0.0 1.2e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGE05674.1 - 3.7e-09 37.2 0.0 1.1e-08 35.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.11 EGE05676.1 - 1e-57 195.1 0.0 1.3e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.32 EGE05677.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGE05677.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGE05677.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGE05677.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGE05677.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGE05677.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGE05677.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGE05677.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EGE05677.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGE05677.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EGE05677.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EGE05677.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EGE05677.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EGE05677.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 EGE05677.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EGE05677.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EGE05677.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EGE05677.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EGE05677.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 EGE05677.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 EGE05677.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EGE05677.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 EGE05677.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 EGE05677.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 EGE05677.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Herpes_UL52 PF03121.15 EGE05678.1 - 0.003 17.4 0.3 0.0047 16.8 0.3 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase SNARE PF05739.19 EGE05679.1 - 7.2e-15 54.7 1.6 1.7e-14 53.6 1.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGE05679.1 - 0.0014 18.3 8.8 0.0027 17.4 8.8 1.5 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 EGE05679.1 - 0.11 12.3 6.5 0.07 12.9 0.8 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.13 EGE05680.1 - 1.9e-17 63.8 0.1 1.1e-16 61.4 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. YscO-like PF16789.5 EGE05680.1 - 0.057 13.5 1.0 0.14 12.2 1.0 1.6 1 0 0 1 1 1 0 YscO-like protein Spc7 PF08317.11 EGE05680.1 - 0.07 12.0 1.2 0.19 10.6 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein CTK3 PF12243.8 EGE05680.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 MCD_N PF17408.2 EGE05680.1 - 0.13 12.4 0.4 6.6 6.9 0.0 3.5 4 0 0 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain YjcZ PF13990.6 EGE05680.1 - 0.21 10.9 3.0 8.9 5.6 0.4 2.3 2 0 0 2 2 2 0 YjcZ-like protein POTRA_TamA_1 PF17243.2 EGE05680.1 - 0.32 11.1 1.7 15 5.8 0.7 3.4 3 0 0 3 3 3 0 POTRA domain TamA domain 1 Clathrin_lg_ch PF01086.17 EGE05681.1 - 7.3e-62 209.4 7.5 8.5e-62 209.2 7.5 1.0 1 0 0 1 1 1 1 Clathrin light chain CdiI_2 PF18593.1 EGE05681.1 - 0.097 13.3 2.0 0.26 11.9 0.1 2.4 3 0 0 3 3 3 0 CdiI immunity protein Acyl_transf_3 PF01757.22 EGE05682.1 - 1.2e-18 67.3 40.0 1.9e-18 66.6 40.0 1.3 1 1 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.8 EGE05684.1 - 4e-55 187.1 0.0 6.2e-32 111.0 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative CDC37_N PF03234.14 EGE05685.1 - 1.5e-50 171.4 2.1 1.5e-50 171.4 2.1 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EGE05685.1 - 8.7e-41 138.6 0.4 2.6e-40 137.0 0.1 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EGE05685.1 - 8.6e-35 118.9 4.4 8.6e-35 118.9 4.4 2.3 3 0 0 3 3 3 1 Cdc37 C terminal domain MecA_N PF05223.11 EGE05685.1 - 0.0038 17.5 2.7 0.0055 17.0 1.0 2.2 2 0 0 2 2 2 1 NTF2-like N-terminal transpeptidase domain DUF3573 PF12097.8 EGE05685.1 - 0.047 12.5 0.5 0.074 11.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Thiamine_BP PF01910.17 EGE05685.1 - 0.058 13.3 0.3 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine-binding protein ABC_membrane PF00664.23 EGE05686.1 - 1.5e-52 178.9 10.5 2e-52 178.5 10.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGE05686.1 - 3.1e-35 121.7 0.0 9.3e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGE05686.1 - 6.5e-07 29.0 0.1 5.1e-05 22.8 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGE05686.1 - 0.0002 21.8 0.9 0.00079 19.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGE05686.1 - 0.0026 18.0 0.1 0.02 15.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGE05686.1 - 0.0057 16.4 0.5 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGE05686.1 - 0.014 15.8 0.0 0.075 13.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EGE05686.1 - 0.03 14.0 0.2 0.5 10.1 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGE05686.1 - 0.042 13.5 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGE05686.1 - 0.047 13.3 0.1 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EGE05686.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGE05686.1 - 0.12 12.4 0.1 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.6 EGE05686.1 - 0.13 12.4 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGE05686.1 - 0.14 12.8 0.3 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGE05686.1 - 0.22 11.8 1.4 2.5 8.4 0.6 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Nucleoside_tran PF01733.18 EGE05687.1 - 1.1e-38 133.4 14.3 1.6e-37 129.6 11.9 2.8 1 1 1 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 EGE05687.1 - 4.9e-06 25.7 33.7 4.9e-05 22.4 31.2 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Ac76 PF05814.11 EGE05687.1 - 0.9 9.6 2.9 1.8 8.7 0.3 2.6 2 0 0 2 2 2 0 Orf76 (Ac76) DUF5090 PF17009.5 EGE05687.1 - 1.8 8.5 7.7 40 4.1 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5090) Gate PF07670.14 EGE05687.1 - 3.7 7.9 9.9 0.65 10.3 4.2 2.6 2 0 0 2 2 2 0 Nucleoside recognition zf-C2H2 PF00096.26 EGE05688.1 - 0.00011 22.5 6.2 0.0023 18.3 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGE05688.1 - 0.0085 16.4 0.6 0.014 15.7 0.6 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EGE05688.1 - 0.24 11.5 0.3 0.24 11.5 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EGE05688.1 - 0.37 11.8 12.5 0.42 11.6 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE05688.1 - 0.93 10.0 12.3 1.8 9.1 2.4 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Metallophos_2 PF12850.7 EGE05689.1 - 7.5e-08 32.7 0.0 2.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGE05689.1 - 8.6e-08 32.9 0.1 1.3e-07 32.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Haspin_kinase PF12330.8 EGE05690.1 - 9e-34 117.0 0.0 6.1e-33 114.2 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGE05690.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1682 PF07946.14 EGE05692.1 - 4.2e-87 292.4 25.5 1e-76 258.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1682) COX7a PF02238.15 EGE05693.1 - 9e-23 80.4 2.3 1.1e-22 80.1 2.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII SYF2 PF08231.12 EGE05696.1 - 4.3e-56 189.7 17.8 4.3e-56 189.7 17.8 2.2 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 EGE05696.1 - 0.081 13.1 0.5 0.081 13.1 0.5 3.5 2 1 2 4 4 4 0 ARD/ARD' family POT1PC PF16686.5 EGE05696.1 - 0.47 10.3 7.1 0.28 11.0 0.4 2.8 3 0 0 3 3 3 0 ssDNA-binding domain of telomere protection protein DUF1797 PF08796.10 EGE05696.1 - 1.1 9.4 4.3 0.58 10.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Ndc1_Nup PF09531.10 EGE05696.1 - 2.2 6.9 7.7 2.5 6.7 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NAD_binding_10 PF13460.6 EGE05697.1 - 3.4e-07 30.3 0.0 1.3e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGE05697.1 - 3e-06 26.9 0.0 7.2e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGE05697.1 - 3.6e-05 22.9 0.0 0.00014 20.9 0.0 1.8 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGE05697.1 - 0.0026 17.3 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EGE05697.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGE05697.1 - 0.011 14.9 0.0 0.029 13.5 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGE05697.1 - 0.019 14.1 0.2 1.4 8.0 0.1 3.1 2 1 0 2 2 2 0 Male sterility protein Pox_RNA_Pol_19 PF05320.12 EGE05697.1 - 0.03 14.3 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SMRP1 PF15181.6 EGE05697.1 - 0.033 13.8 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 KR PF08659.10 EGE05697.1 - 0.042 13.8 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 KR domain NmrA PF05368.13 EGE05697.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EGE05697.1 - 0.09 11.9 0.0 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein YEATS PF03366.16 EGE05698.1 - 1.2e-36 124.5 0.7 1.9e-36 123.9 0.7 1.3 1 0 0 1 1 1 1 YEATS family YebG PF07130.12 EGE05698.1 - 0.11 12.4 0.2 0.38 10.6 0.1 1.8 2 0 0 2 2 2 0 YebG protein Rep_fac_C PF08542.11 EGE05699.1 - 2.6e-24 85.4 0.1 9.5e-24 83.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGE05699.1 - 6e-12 45.6 0.0 1e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EGE05699.1 - 3.3e-11 43.7 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGE05699.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE05699.1 - 3.2e-06 27.6 0.0 0.00017 22.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGE05699.1 - 2.8e-05 24.0 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EGE05699.1 - 5.3e-05 23.0 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE05699.1 - 0.00011 22.4 0.1 0.14 12.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EGE05699.1 - 0.00023 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EGE05699.1 - 0.00058 19.7 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EGE05699.1 - 0.0023 17.4 0.0 0.023 14.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 EGE05699.1 - 0.0054 17.1 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_24 PF13479.6 EGE05699.1 - 0.0067 16.2 0.0 0.03 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGE05699.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 EGE05699.1 - 0.0071 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 EGE05699.1 - 0.016 15.5 0.1 0.042 14.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EGE05699.1 - 0.018 14.8 0.1 0.92 9.3 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 EGE05699.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGE05699.1 - 0.024 14.5 0.2 0.08 12.9 0.1 1.9 1 1 1 2 2 2 0 NTPase TniB PF05621.11 EGE05699.1 - 0.029 13.8 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein KTI12 PF08433.10 EGE05699.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EGE05699.1 - 0.11 12.2 0.1 0.37 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 EGE05700.1 - 1.6e-05 24.4 0.0 0.0032 16.9 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1338 PF07063.13 EGE05701.1 - 2.5e-107 358.8 0.0 3e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) DUF410 PF04190.13 EGE05703.1 - 3e-87 292.6 0.0 3.6e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 EGE05704.1 - 5e-27 93.9 0.1 1.2e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.17 EGE05705.1 - 5.7e-62 209.5 0.1 8.6e-62 208.9 0.1 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EGE05705.1 - 4.4e-05 23.0 0.1 0.00015 21.3 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EGE05705.1 - 8.3e-05 22.8 2.2 0.0029 17.8 0.3 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE05705.1 - 0.0034 17.9 2.3 1 9.9 0.0 3.3 2 1 0 3 3 3 1 AAA domain zf-met PF12874.7 EGE05705.1 - 0.0042 17.4 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_25 PF13481.6 EGE05705.1 - 0.0075 15.9 0.4 0.042 13.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain zf-C2H2_2 PF12756.7 EGE05705.1 - 0.01 16.2 0.5 0.031 14.6 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGE05705.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PhoH PF02562.16 EGE05705.1 - 0.091 12.2 0.4 0.21 11.0 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 EGE05705.1 - 0.12 12.8 0.0 0.96 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF3811 PF11656.8 EGE05705.1 - 2 8.8 7.0 3.9 7.9 0.1 3.0 3 0 0 3 3 3 0 YjbD family (DUF3811) DUF87 PF01935.17 EGE05705.1 - 5.2 7.1 10.1 0.99 9.5 0.1 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 EGE05706.1 - 3.2e-05 24.5 0.0 0.00012 22.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGE05706.1 - 0.00092 19.1 0.2 0.0014 18.5 0.2 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE05706.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain WD40 PF00400.32 EGE05707.1 - 1e-31 108.5 26.5 4.8e-05 24.0 0.0 11.8 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05707.1 - 3.2e-06 27.3 0.5 45 4.5 0.0 6.7 6 2 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4596 PF15363.6 EGE05707.1 - 0.17 12.1 1.3 0.48 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Urm1 PF09138.11 EGE05708.1 - 1.1e-34 118.6 0.0 1.3e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGE05708.1 - 0.038 14.6 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.18 EGE05709.1 - 6e-62 208.9 0.0 9.4e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGE05709.1 - 1.1e-19 70.9 0.0 5.3e-19 68.7 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGE05709.1 - 0.094 12.9 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.22 EGE05710.1 - 6.1e-81 271.8 0.0 7.1e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 EGE05710.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term TMEM154 PF15102.6 EGE05712.1 - 0.078 12.9 0.0 0.09 12.7 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family VMA21 PF09446.10 EGE05713.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 VMA21-like domain Pkinase PF00069.25 EGE05714.1 - 2.8e-64 217.0 0.0 3.4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05714.1 - 7.5e-24 84.4 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE05714.1 - 3e-06 26.8 0.0 9.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGE05714.1 - 0.00071 19.6 0.3 0.021 14.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family MIF4G_like PF09088.11 EGE05715.1 - 6e-88 293.6 0.2 1.2e-87 292.7 0.2 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EGE05715.1 - 6.9e-72 242.1 0.0 1.1e-71 241.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like TonB_dep_Rec PF00593.24 EGE05715.1 - 0.35 10.7 0.5 0.53 10.1 0.5 1.1 1 0 0 1 1 1 0 TonB dependent receptor WD40 PF00400.32 EGE05717.1 - 2.5e-58 192.6 15.8 4.2e-09 36.9 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EGE05717.1 - 1.3e-18 67.1 9.3 2.1e-18 66.4 9.3 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EGE05717.1 - 1.3e-15 57.4 0.0 0.0059 16.9 0.0 6.7 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGE05717.1 - 9.6e-08 31.7 0.0 0.064 12.6 0.0 4.2 2 1 2 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 EGE05717.1 - 1.2e-05 24.0 0.5 0.00015 20.4 0.2 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EGE05717.1 - 2.1e-05 23.7 0.2 0.78 8.6 0.0 4.6 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGE05717.1 - 6.5e-05 21.8 0.1 0.25 9.9 0.0 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EGE05717.1 - 0.0011 18.9 0.0 0.071 13.0 0.0 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A MMS1_N PF10433.9 EGE05717.1 - 0.013 14.2 0.0 2.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.6 EGE05717.1 - 0.02 14.2 0.0 6.6 6.0 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EGE05717.1 - 0.022 14.7 0.0 20 5.3 0.0 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TPX2 PF06886.11 EGE05717.1 - 5.1 7.4 6.7 11 6.4 6.7 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) zf-C2H2 PF00096.26 EGE05719.1 - 1.7e-17 62.8 23.3 0.00011 22.4 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE05719.1 - 2.5e-15 56.1 21.9 1.4e-07 31.7 2.2 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE05719.1 - 1.4e-09 37.9 22.7 0.039 14.8 0.6 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EGE05719.1 - 4.4e-05 23.7 1.5 0.046 13.9 0.1 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger zf-met PF12874.7 EGE05719.1 - 0.00056 20.2 7.0 0.24 11.8 0.2 4.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGE05719.1 - 0.12 12.4 10.9 0.19 11.8 0.5 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 EGE05719.1 - 0.19 11.6 10.2 7.2 6.6 0.4 4.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 EGE05719.1 - 0.46 10.8 3.1 1 9.6 0.6 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Mito_carr PF00153.27 EGE05720.1 - 7.5e-59 195.7 3.4 6e-23 80.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 EGE05721.1 - 3.3e-22 77.8 0.3 3.8e-22 77.6 0.3 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.22 EGE05722.1 - 8.4e-29 99.2 0.1 1.8e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE05722.1 - 0.00079 19.5 0.0 0.0048 17.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EGE05722.1 - 0.0022 17.6 0.0 0.088 12.4 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGE05722.1 - 0.0096 16.0 0.3 0.78 9.9 0.1 2.2 2 0 0 2 2 2 1 Limkain b1 OB_RNB PF08206.11 EGE05722.1 - 0.096 12.4 0.1 6.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 EGE05722.1 - 0.11 12.8 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF2015 PF09435.10 EGE05723.1 - 9.8e-44 147.8 0.0 1.1e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EGE05724.1 - 1e-31 110.1 0.2 1.5e-31 109.5 0.1 1.3 1 1 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 EGE05725.1 - 1.5e-44 151.5 0.0 2.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGE05725.1 - 2.7e-42 144.6 0.0 3.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EGE05725.1 - 0.00051 19.1 0.0 0.00069 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.16 EGE05726.1 - 4e-42 143.4 0.0 4.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Glyco_transf_90 PF05686.12 EGE05727.1 - 4.4e-17 62.1 6.7 2.3e-13 49.8 4.7 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 PINIT PF14324.6 EGE05728.1 - 6.9e-40 136.8 0.0 1.1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EGE05728.1 - 3.8e-22 77.8 6.5 7.5e-22 76.8 6.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EGE05728.1 - 1.1e-06 28.3 0.8 2.7e-06 27.0 0.8 1.7 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EGE05728.1 - 7.4e-06 25.7 2.1 1.5e-05 24.7 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 EGE05728.1 - 0.15 12.1 1.7 0.4 10.8 1.7 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_2 PF13923.6 EGE05728.1 - 4.3 7.3 6.4 9.3 6.2 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2423 PF10338.9 EGE05729.1 - 1.6e-20 73.0 0.5 1.6e-20 73.0 0.5 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) Red1 PF07964.11 EGE05731.1 - 0.031 12.5 4.2 0.037 12.3 4.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Caveolin PF01146.17 EGE05731.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Caveolin MARCKS PF02063.17 EGE05731.1 - 0.41 10.6 8.6 0.075 13.0 0.8 2.0 2 0 0 2 2 2 0 MARCKS family VIGSSK PF14773.6 EGE05731.1 - 0.58 10.3 2.8 21 5.3 0.1 2.8 2 1 1 3 3 3 0 Helicase-associated putative binding domain, C-terminal Aldedh PF00171.22 EGE05733.1 - 1.7e-131 438.9 0.0 1.9e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGE05733.1 - 0.00019 20.6 0.0 0.00087 18.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) CdiI_2 PF18593.1 EGE05733.1 - 0.17 12.6 0.1 0.71 10.6 0.0 2.0 2 0 0 2 2 2 0 CdiI immunity protein Lipase_GDSL_2 PF13472.6 EGE05735.1 - 1.7e-12 48.1 0.2 4.3e-11 43.5 0.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGE05735.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TFIIA_gamma_N PF02268.16 EGE05736.1 - 1.7e-24 85.5 0.1 2.4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EGE05736.1 - 9.4e-24 83.3 1.0 9.4e-24 83.3 1.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit CENP-B_dimeris PF09026.10 EGE05738.1 - 1.1 9.7 6.2 2.2 8.8 6.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hexokinase_1 PF00349.21 EGE05739.1 - 3e-61 206.8 0.0 4.7e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EGE05739.1 - 9.8e-44 149.6 0.0 3.8e-43 147.6 0.0 1.9 1 1 0 1 1 1 1 Hexokinase SR-25 PF10500.9 EGE05739.1 - 0.054 13.1 5.4 0.085 12.5 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GILT PF03227.16 EGE05740.1 - 6.2e-15 55.4 1.7 4.9e-14 52.5 1.0 2.5 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) MFS_1 PF07690.16 EGE05742.1 - 1.6e-23 83.2 17.3 2.1e-23 82.9 17.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GCP_N_terminal PF17681.1 EGE05743.1 - 2.6e-30 106.1 0.0 9.6e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGE05743.1 - 0.01 15.4 1.5 1.3 8.4 0.1 2.3 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal DUF3459 PF11941.8 EGE05743.1 - 0.039 14.3 0.1 0.085 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) ThiF PF00899.21 EGE05744.1 - 2.7e-113 377.3 0.0 3.9e-75 252.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGE05744.1 - 5.7e-96 321.3 1.5 3.2e-95 318.8 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGE05744.1 - 2.7e-28 98.5 0.0 6.9e-28 97.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EGE05744.1 - 2.1e-23 82.3 1.3 2.1e-23 82.3 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 EGE05744.1 - 1.3e-22 79.8 0.1 2.8e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain GST_N_2 PF13409.6 EGE05745.1 - 1.1e-22 80.1 0.0 2.7e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE05745.1 - 1.6e-13 50.4 0.0 3.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGE05745.1 - 6.8e-06 26.4 0.1 0.00044 20.6 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGE05745.1 - 4.1e-05 23.7 0.0 0.00013 22.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Mito_carr PF00153.27 EGE05746.1 - 9.4e-67 221.0 5.3 6.9e-23 80.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGE05746.1 - 3.5e-22 78.6 5.6 1.4e-11 44.7 0.5 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGE05746.1 - 6e-19 66.1 7.3 4.1e-05 22.8 1.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGE05746.1 - 4e-17 60.6 11.0 9.9e-06 25.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGE05746.1 - 1.7e-16 58.9 11.3 1.4e-05 24.3 1.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGE05746.1 - 3.1e-12 46.1 3.6 6e-06 26.0 0.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGE05746.1 - 2e-09 37.8 0.3 0.0004 20.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGE05746.1 - 0.00099 19.0 4.1 0.29 11.1 0.5 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGE05746.1 - 0.0059 16.5 0.2 3.2 7.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGE05746.1 - 0.022 15.1 0.0 6.6 7.1 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain Cyclin_N PF00134.23 EGE05747.1 - 3.3e-11 43.0 0.1 4.8e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGE05747.1 - 0.026 14.9 0.1 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain TPPII_N PF12583.8 EGE05747.1 - 0.91 10.1 5.9 1.6 9.3 5.9 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal K_channel_TID PF07941.11 EGE05747.1 - 4.7 7.7 13.2 5.7 7.5 8.8 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4452 PF14618.6 EGE05748.1 - 8.6e-52 175.4 6.7 8.6e-52 175.4 6.7 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4452) Zip PF02535.22 EGE05748.1 - 0.049 12.8 3.0 0.055 12.7 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MAP65_ASE1 PF03999.12 EGE05748.1 - 0.71 8.5 3.7 0.63 8.7 3.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Rubella_E2 PF05749.11 EGE05748.1 - 1.8 8.0 10.0 0.059 12.8 3.6 1.6 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 FAM76 PF16046.5 EGE05748.1 - 2.2 7.6 7.0 3 7.1 7.0 1.2 1 0 0 1 1 1 0 FAM76 protein PT PF04886.12 EGE05749.1 - 0.032 13.8 9.5 0.032 13.8 9.5 1.7 2 0 0 2 2 2 0 PT repeat FerI PF08151.12 EGE05749.1 - 0.092 12.8 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 FerI (NUC094) domain F-box-like PF12937.7 EGE05751.1 - 0.00029 20.6 0.8 0.00067 19.5 0.3 2.0 2 0 0 2 2 2 1 F-box-like Chal_sti_synt_C PF02797.15 EGE05752.1 - 3.1e-18 66.2 0.0 5.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGE05752.1 - 3.8e-14 52.7 0.1 6.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III_C PF08541.10 EGE05752.1 - 0.0019 18.3 0.0 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.28 EGE05754.1 - 1.3e-199 663.1 0.0 1.5e-75 254.4 0.0 3.1 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGE05754.1 - 1.1e-55 189.2 0.0 1.8e-27 96.2 0.0 3.6 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EGE05754.1 - 2.4e-22 79.1 4.3 1.6e-12 47.5 0.1 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE05754.1 - 3.1e-08 34.5 0.0 0.0013 19.7 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EGE05755.1 - 1.4e-27 96.6 35.9 7.1e-27 94.2 26.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05755.1 - 2.2e-06 26.8 1.9 2.2e-06 26.8 1.9 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EGE05755.1 - 0.00062 18.3 2.9 0.00084 17.9 1.8 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PRIMA1 PF16101.5 EGE05755.1 - 0.089 12.8 0.3 0.089 12.8 0.3 2.2 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 SNARE PF05739.19 EGE05756.1 - 6.2e-10 38.9 0.1 1.2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 SNARE domain DUF1676 PF07898.13 EGE05756.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Spectrin PF00435.21 EGE05756.1 - 0.022 15.3 1.5 0.06 13.8 0.1 2.1 2 0 0 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.12 EGE05756.1 - 0.42 10.7 3.6 0.22 11.6 1.0 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-TRAF PF02176.18 EGE05757.1 - 8.8e-08 32.7 40.9 1.1e-05 26.0 8.0 4.7 2 1 3 5 5 4 4 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGE05757.1 - 2.1e-07 31.3 10.2 2.1e-07 31.3 10.2 3.2 1 1 1 3 3 2 1 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGE05757.1 - 0.00039 20.7 15.3 0.00039 20.7 15.3 4.3 2 1 3 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 EGE05757.1 - 0.0016 18.3 14.0 0.0016 18.3 14.0 3.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGE05757.1 - 0.0034 17.4 13.2 0.0034 17.4 13.2 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGE05757.1 - 0.012 15.4 15.1 0.012 15.4 15.1 4.0 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE05757.1 - 0.023 14.9 14.9 0.023 14.9 14.9 3.2 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING TSC22 PF01166.18 EGE05757.1 - 0.095 13.0 0.9 5.3 7.4 0.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family zf_UBZ PF18439.1 EGE05757.1 - 4.6 6.9 13.5 4.7 6.9 2.5 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Sina PF03145.16 EGE05757.1 - 5 7.0 21.8 9 6.2 6.7 2.7 1 1 1 2 2 2 0 Seven in absentia protein family zf-RING_6 PF14835.6 EGE05757.1 - 7.2 6.6 14.7 20 5.1 12.3 3.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Het-C PF07217.11 EGE05759.1 - 1.8e-271 901.6 0.0 2.2e-271 901.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Ank_5 PF13857.6 EGE05760.1 - 3e-16 59.3 0.2 5.7e-06 26.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE05760.1 - 1.5e-13 51.1 0.0 0.00074 20.0 0.0 4.8 5 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE05760.1 - 2.5e-13 48.9 0.2 0.0012 19.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EGE05760.1 - 2e-12 47.3 0.0 0.0025 18.3 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EGE05760.1 - 4.6e-09 36.3 0.3 0.0069 16.8 0.0 4.3 5 1 0 5 5 5 2 Ankyrin repeat IBN_N PF03810.19 EGE05761.1 - 1.3e-10 41.0 0.7 1.1e-08 34.9 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGE05761.1 - 2.5e-05 24.4 0.1 0.00088 19.4 0.1 3.2 2 1 0 2 2 2 1 Exportin 1-like protein Proteasom_PSMB PF10508.9 EGE05761.1 - 8.3e-05 21.3 1.7 0.0027 16.3 0.0 3.0 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit RIX1 PF08167.12 EGE05761.1 - 0.00067 19.5 3.1 0.013 15.2 0.0 3.9 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis CAS_CSE1 PF03378.15 EGE05761.1 - 0.00095 17.8 0.2 0.0049 15.4 0.0 2.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus HORMA PF02301.18 EGE05763.1 - 3.6e-10 39.8 0.0 4.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IBR PF01485.21 EGE05764.1 - 2.2e-07 31.0 7.1 2.2e-07 31.0 7.1 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Pkinase PF00069.25 EGE05765.1 - 4.3e-09 36.1 0.1 4e-07 29.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05765.1 - 0.0081 15.5 0.1 0.028 13.7 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE05765.1 - 0.015 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGE05765.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pectate_lyase22 PF14583.6 EGE05765.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase Acetyltransf_7 PF13508.7 EGE05767.1 - 0.00024 21.4 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE05767.1 - 0.0031 17.6 0.0 0.0082 16.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE05767.1 - 0.039 14.1 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGE05767.1 - 0.06 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 EGE05767.1 - 0.12 12.4 0.0 0.54 10.2 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE05767.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Dcc1 PF09724.9 EGE05768.1 - 2.6e-10 40.1 0.0 3e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF4855 PF16147.5 EGE05768.1 - 0.075 12.1 0.0 6.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4855) Anp1 PF03452.14 EGE05769.1 - 2.1e-111 371.5 0.0 2.1e-111 371.5 0.0 2.5 2 1 0 3 3 3 1 Anp1 Smg8_Smg9 PF10220.9 EGE05769.1 - 1.2 7.4 17.8 1.9 6.7 17.8 1.4 1 0 0 1 1 1 0 Smg8_Smg9 tRNA_bind PF01588.20 EGE05770.1 - 2.4e-20 72.5 0.0 1.2e-19 70.2 0.0 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 EGE05770.1 - 0.029 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Asp PF00026.23 EGE05771.1 - 5.5e-60 203.4 0.0 6.4e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGE05771.1 - 6.9e-09 36.2 0.3 0.0041 17.4 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGE05771.1 - 1.3e-06 29.0 0.8 0.0067 17.0 0.2 2.7 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EGE05771.1 - 5.7e-05 23.6 0.2 0.029 14.9 0.1 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease ParA PF10609.9 EGE05772.1 - 2.6e-95 318.6 0.0 3.1e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGE05772.1 - 5.3e-08 33.0 0.0 1.8e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGE05772.1 - 5.6e-06 26.4 0.0 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGE05772.1 - 1e-05 24.9 1.2 0.00023 20.4 0.3 2.5 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EGE05772.1 - 0.0042 16.4 0.0 0.0091 15.3 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EGE05772.1 - 0.005 16.7 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 EGE05772.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EGE05772.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EGE05772.1 - 0.03 13.9 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGE05772.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGE05772.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EGE05772.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGE05772.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EGE05772.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PEMT PF04191.13 EGE05773.1 - 2.6e-60 201.4 9.3 1.7e-36 124.8 0.7 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 EGE05773.1 - 0.037 14.6 0.1 1.4 9.6 0.0 2.4 2 0 0 2 2 2 0 SKICH domain HECW_N PF16562.5 EGE05773.1 - 0.038 13.8 0.1 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 EGE05774.1 - 3.1e-26 92.4 0.1 6e-26 91.5 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lactamase_B PF00753.27 EGE05775.1 - 4.3e-09 36.6 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGE05775.1 - 0.00067 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Bim_N PF06773.11 EGE05776.1 - 0.067 12.9 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Bim protein N-terminus MAGUK_N_PEST PF10608.9 EGE05776.1 - 0.16 12.4 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK GST_N_3 PF13417.6 EGE05777.1 - 0.094 13.1 0.4 0.29 11.6 0.1 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 EGE05778.1 - 1.2e-34 119.8 31.8 2.5e-24 85.9 12.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05778.1 - 3.1e-08 32.9 8.5 3.1e-08 32.9 8.5 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EGE05778.1 - 0.043 12.2 1.2 0.071 11.5 1.2 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector ProRS-C_1 PF09180.11 EGE05779.1 - 3.5e-23 81.6 3.7 7.4e-23 80.5 3.4 1.7 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGE05779.1 - 1e-17 64.7 0.0 1.8e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGE05779.1 - 1.6e-12 47.4 0.0 4.3e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 EGE05780.1 - 4.3e-150 500.6 16.5 4.9e-150 500.4 16.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 EGE05781.1 - 5.6e-14 52.3 8.8 0.00039 21.2 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE05781.1 - 1.7e-07 31.5 0.0 0.0014 18.8 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain S1 PF00575.23 EGE05782.1 - 7.1e-64 212.1 36.3 1.5e-15 57.2 0.5 11.4 11 0 0 11 11 11 9 S1 RNA binding domain TPR_19 PF14559.6 EGE05782.1 - 3.3e-05 24.3 0.0 0.0099 16.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EGE05782.1 - 6.6e-05 22.8 0.0 0.98 9.4 0.0 5.0 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 EGE05782.1 - 0.00043 20.9 0.0 0.51 11.3 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Suf PF05843.14 EGE05782.1 - 0.0011 19.1 11.9 0.017 15.2 0.0 4.4 2 2 2 4 4 3 2 Suppressor of forked protein (Suf) PCB_OB PF17092.5 EGE05782.1 - 0.002 18.9 12.5 2.8 8.7 0.0 6.5 6 0 0 6 6 6 2 Penicillin-binding protein OB-like domain NRDE-2 PF08424.10 EGE05782.1 - 0.014 14.6 0.0 0.072 12.2 0.0 2.1 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EGE05782.1 - 0.014 16.0 0.0 23 5.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EGE05782.1 - 0.085 13.1 0.0 30 5.1 0.0 3.3 2 1 1 3 3 3 0 PPR repeat Cue1_U7BR PF18499.1 EGE05782.1 - 0.11 12.5 1.4 0.16 12.0 0.0 2.1 2 0 0 2 2 1 0 Ubc7p-binding region of Cue1 S1_2 PF13509.6 EGE05782.1 - 1.1 9.4 4.0 25 5.0 0.0 4.8 6 0 0 6 6 6 0 S1 domain Phage_lysozyme PF00959.19 EGE05783.1 - 1.5e-11 44.7 0.0 1.8e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme UreD PF01774.17 EGE05784.1 - 1.6e-53 181.8 0.1 3e-33 115.5 0.0 2.1 1 1 1 2 2 2 2 UreD urease accessory protein STAG PF08514.11 EGE05785.1 - 4.2e-40 136.2 1.5 4.2e-40 136.2 1.5 3.7 3 0 0 3 3 3 1 STAG domain YL1 PF05764.13 EGE05785.1 - 0.0042 17.3 21.8 0.0042 17.3 21.8 4.7 4 1 1 5 5 5 1 YL1 nuclear protein HEAT_2 PF13646.6 EGE05785.1 - 0.0049 17.2 0.0 0.24 11.8 0.3 3.1 1 1 1 2 2 2 1 HEAT repeats FAM209 PF15206.6 EGE05785.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.7 2 0 0 2 2 2 0 FAM209 family Allexi_40kDa PF05549.11 EGE05785.1 - 5.7 6.4 12.6 0.19 11.2 0.1 3.8 2 2 1 3 3 3 0 Allexivirus 40kDa protein Acatn PF13000.7 EGE05786.1 - 4.5e-115 385.2 6.6 1.3e-44 152.7 0.0 3.0 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 GFA PF04828.14 EGE05786.1 - 1.6e-13 50.8 2.8 3e-13 49.9 2.8 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CENP-O PF09496.10 EGE05787.1 - 9.6e-66 221.8 0.0 1.3e-64 218.1 0.0 2.0 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component MreB_Mbl PF06723.13 EGE05789.1 - 0.23 10.2 0.2 0.33 9.7 0.2 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Atg29_N PF18388.1 EGE05790.1 - 2.9e-21 75.0 0.4 5.7e-21 74.1 0.4 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain DFP PF04127.15 EGE05792.1 - 1.4e-12 47.8 0.0 6.7e-05 22.8 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Polysacc_deac_1 PF01522.21 EGE05793.1 - 8.1e-19 67.7 0.0 1.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGE05793.1 - 0.0039 16.4 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DEAD PF00270.29 EGE05794.1 - 3.5e-42 144.1 0.0 6.1e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE05794.1 - 2.1e-27 95.6 0.0 5.9e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EGE05794.1 - 0.018 13.8 0.0 2.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 EGE05794.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Glyoxal_oxid_N PF07250.11 EGE05795.1 - 1.8e-37 128.9 0.0 9.1e-37 126.5 0.0 2.2 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EGE05795.1 - 1.6e-24 86.0 0.2 3.4e-24 85.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 EGE05795.1 - 5.4e-06 26.8 20.2 5.4e-06 26.8 20.2 2.4 2 0 0 2 2 2 1 Chitin recognition protein Kelch_6 PF13964.6 EGE05795.1 - 0.00094 19.4 0.4 23 5.5 0.0 5.6 6 0 0 6 6 6 1 Kelch motif PQQ_2 PF13360.6 EGE05795.1 - 0.085 12.4 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Fumble PF03630.14 EGE05796.1 - 1.3e-144 481.5 0.9 1.6e-144 481.1 0.9 1.1 1 0 0 1 1 1 1 Fumble GPI2 PF06432.11 EGE05797.1 - 3.2e-129 430.3 6.4 3.9e-129 430.0 6.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Intg_mem_TP0381 PF09529.10 EGE05797.1 - 3.7 7.0 8.8 3.1 7.2 0.4 2.7 3 0 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) Macoilin PF09726.9 EGE05798.1 - 0.095 11.2 10.7 0.11 11.0 10.7 1.0 1 0 0 1 1 1 0 Macoilin family PTPRCAP PF15713.5 EGE05798.1 - 0.52 10.6 12.7 0.052 13.8 6.6 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated EMC3_TMCO1 PF01956.16 EGE05798.1 - 1.1 9.0 2.2 1.6 8.4 2.2 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like AIF_C PF14721.6 EGE05798.1 - 3.7 7.9 9.3 51 4.2 7.8 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_hydro_18 PF00704.28 EGE05801.1 - 2.4e-22 80.0 0.1 1.1e-21 77.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SLATT_5 PF18160.1 EGE05803.1 - 0.47 9.8 2.5 0.54 9.6 0.5 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Bunya_G2 PF03563.13 EGE05803.1 - 1.9 7.7 6.2 3.3 6.9 6.2 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Hormone_2 PF00123.20 EGE05803.1 - 2.9 7.9 5.9 14 5.7 0.7 2.5 2 0 0 2 2 2 0 Peptide hormone AA_permease_2 PF13520.6 EGE05804.1 - 2.4e-47 161.7 52.9 3.1e-47 161.3 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE05804.1 - 1.3e-23 83.4 44.7 1.7e-23 83.0 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05806.1 - 1.1e-48 166.1 46.5 1.5e-48 165.7 46.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE05806.1 - 5e-29 101.2 41.4 6.6e-29 100.8 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease Dynamin_M PF01031.20 EGE05807.1 - 1.2e-27 96.9 0.3 2.2e-26 92.7 0.0 2.7 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGE05807.1 - 7.1e-27 94.5 0.0 1.6e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGE05807.1 - 0.0019 18.3 0.0 0.011 15.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase OSCP PF00213.18 EGE05807.1 - 0.082 13.0 0.0 9.1 6.4 0.0 2.7 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit AAA_16 PF13191.6 EGE05807.1 - 0.38 11.1 4.8 0.59 10.5 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain GED PF02212.18 EGE05807.1 - 6.2 7.0 11.0 0.79 9.9 0.7 4.0 5 0 0 5 5 5 0 Dynamin GTPase effector domain DUF2254 PF10011.9 EGE05808.1 - 0.047 12.5 0.8 0.068 12.0 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) HemY_N PF07219.13 EGE05808.1 - 0.15 12.3 1.3 0.3 11.3 1.3 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Col_cuticle_N PF01484.17 EGE05808.1 - 0.82 9.8 6.2 2 8.6 6.2 1.7 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain 5_nucleotid_C PF02872.18 EGE05810.1 - 4.7e-33 114.6 0.1 2e-31 109.4 0.1 2.4 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGE05810.1 - 0.0003 21.3 1.4 0.00067 20.2 1.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TMEM154 PF15102.6 EGE05811.1 - 0.0039 17.1 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 TMEM154 protein family DUF5385 PF17359.2 EGE05811.1 - 0.014 14.9 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Protocadherin PF08374.11 EGE05811.1 - 0.031 14.3 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF5367 PF17329.2 EGE05811.1 - 0.035 14.2 0.1 0.05 13.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5367) Chordopox_A13L PF05961.11 EGE05811.1 - 0.044 14.0 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SIT PF15330.6 EGE05811.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Kinetochor_Ybp2 PF08568.10 EGE05811.1 - 0.16 10.4 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Aldedh PF00171.22 EGE05812.1 - 9.2e-153 509.0 0.1 1.1e-152 508.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_trans_2_3 PF13632.6 EGE05814.1 - 0.026 14.4 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Gln-synt_C PF00120.24 EGE05818.1 - 6.9e-63 212.7 0.0 2.2e-62 211.1 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EGE05818.1 - 5.9e-14 52.5 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 EGE05818.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain MFS_1 PF07690.16 EGE05819.1 - 3.3e-36 125.0 25.3 3.5e-36 124.8 22.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05819.1 - 3.8e-14 52.4 9.8 3.8e-14 52.4 9.8 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGE05819.1 - 0.00026 19.6 3.3 0.00042 18.9 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFA1_2 PF17317.2 EGE05819.1 - 0.19 11.5 0.7 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 UPF0016 PF01169.19 EGE05823.1 - 4.9e-39 132.5 26.3 1.7e-19 69.9 7.5 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EGE05823.1 - 0.02 14.6 0.1 0.02 14.6 0.1 2.2 2 0 0 2 2 2 0 Putative manganese efflux pump DUF2070 PF09843.9 EGE05823.1 - 0.025 12.9 2.1 0.04 12.2 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4614 PF15391.6 EGE05823.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4614) Myb_DNA-binding PF00249.31 EGE05825.1 - 0.00014 22.0 0.3 0.00031 20.9 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRF PF08558.10 EGE05825.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Annexin PF00191.20 EGE05826.1 - 2.2e-13 50.1 5.9 0.0024 17.9 0.1 4.6 4 1 0 4 4 4 4 Annexin Ribosomal_L21e PF01157.18 EGE05827.1 - 1.5e-38 130.7 4.4 1.5e-38 130.7 4.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 EGE05827.1 - 0.25 11.2 2.7 1.2 9.1 0.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 EGE05828.1 - 3.7e-12 45.8 1.3 3.7e-12 45.8 1.3 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EGE05828.1 - 1.9e-06 28.7 0.2 4e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SCIMP PF15050.6 EGE05829.1 - 0.22 12.0 0.4 0.57 10.6 0.4 1.7 1 0 0 1 1 1 0 SCIMP protein Vault_2 PF17794.1 EGE05829.1 - 0.24 11.8 0.3 0.48 10.8 0.3 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain Amidoligase_2 PF12224.8 EGE05830.1 - 4.3e-08 33.1 0.0 0.003 17.3 0.0 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme Vps62 PF06101.11 EGE05832.1 - 2.4e-09 36.1 0.9 3e-07 29.2 0.4 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Tau95_N PF17682.1 EGE05833.1 - 0.12 12.6 0.3 0.15 12.3 0.3 1.1 1 0 0 1 1 1 0 Tau95 Triple barrel domain NOA36 PF06524.12 EGE05833.1 - 0.13 11.5 4.4 0.14 11.4 4.4 1.1 1 0 0 1 1 1 0 NOA36 protein Med4 PF10018.9 EGE05833.1 - 0.19 11.4 7.8 0.23 11.1 7.8 1.0 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3774 PF12609.8 EGE05833.1 - 0.27 12.3 8.3 0.73 10.9 8.3 1.7 1 1 0 1 1 1 0 Wound-induced protein RPN2_C PF18004.1 EGE05833.1 - 0.42 10.5 7.9 0.51 10.2 7.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Myc_N PF01056.18 EGE05833.1 - 0.51 10.2 5.7 0.6 9.9 5.7 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Connexin PF00029.19 EGE05833.1 - 0.61 9.8 2.1 0.59 9.8 2.1 1.1 1 0 0 1 1 1 0 Connexin Sporozoite_P67 PF05642.11 EGE05833.1 - 0.65 8.0 4.3 0.64 8.0 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen V_ATPase_I PF01496.19 EGE05833.1 - 0.71 7.7 1.7 0.79 7.6 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.13 EGE05833.1 - 1.4 7.8 11.3 1.5 7.8 11.3 1.0 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 EGE05833.1 - 2.3 6.4 7.3 2.2 6.4 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 EGE05833.1 - 4.6 6.0 6.9 4.8 5.9 6.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 EGE05833.1 - 4.8 7.6 12.7 0.88 10.0 9.3 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AC_N PF16214.5 EGE05833.1 - 4.9 6.2 8.2 5.8 5.9 8.2 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Presenilin PF01080.17 EGE05833.1 - 5.2 5.7 4.7 5.6 5.6 4.7 1.0 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 EGE05833.1 - 9.1 4.2 12.4 10 4.1 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Septin PF00735.18 EGE05834.1 - 1.7e-34 119.4 0.0 1.4e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EGE05834.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EGE05834.1 - 0.14 12.7 0.7 0.49 10.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGE05834.1 - 0.21 11.6 1.3 0.74 9.8 0.0 2.5 3 0 0 3 3 3 0 Dynamin family DUF3275 PF11679.8 EGE05834.1 - 0.82 9.6 4.8 2.4 8.1 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF3235 PF11574.8 EGE05834.1 - 2.6 9.0 7.4 0.39 11.6 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) SecE PF00584.20 EGE05838.1 - 3.9e-11 42.7 0.0 5.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 EGE05839.1 - 3.4e-06 26.8 0.0 5.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYDLN_acid PF09538.10 EGE05839.1 - 0.066 13.9 2.7 0.14 12.8 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Menin PF05053.13 EGE05839.1 - 1.3 7.3 9.7 2 6.7 9.7 1.2 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.10 EGE05839.1 - 2.7 6.6 5.1 3.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGE05839.1 - 4.5 5.9 8.0 5.6 5.6 8.0 1.2 1 0 0 1 1 1 0 Presenilin WD40 PF00400.32 EGE05840.1 - 3.9e-19 68.6 16.0 0.0011 19.8 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGE05840.1 - 2.8e-06 26.1 0.5 0.019 13.5 0.0 3.9 4 0 0 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EGE05840.1 - 1.7e-05 25.0 0.0 0.35 11.2 0.0 4.3 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGE05840.1 - 0.00061 20.2 3.7 0.19 12.3 0.1 4.5 4 0 0 4 4 4 1 PQQ-like domain PD40 PF07676.12 EGE05840.1 - 0.17 11.9 3.5 0.3 11.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DNA_pol_phi PF04931.13 EGE05840.1 - 1.4 6.9 22.7 1.9 6.5 22.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGE05840.1 - 2.2 6.4 13.1 3 6.0 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGE05840.1 - 3.8 6.8 13.6 5.5 6.3 13.6 1.1 1 0 0 1 1 1 0 SDA1 PX PF00787.24 EGE05841.1 - 3.1e-27 94.8 0.2 3.7e-27 94.6 0.2 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.6 EGE05842.1 - 1.3e-09 38.1 0.2 2.4e-07 30.9 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE05842.1 - 4.1e-05 23.7 0.1 0.0041 17.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain RasGEF PF00617.19 EGE05845.1 - 4.9e-05 23.6 0.0 0.00015 22.0 0.0 1.8 1 1 0 1 1 1 1 RasGEF domain UPF0139 PF03669.13 EGE05846.1 - 1.4e-08 34.5 0.1 1.7e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DNA_pol_B PF00136.21 EGE05847.1 - 1.1e-94 317.7 0.1 2.9e-94 316.4 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.6 EGE05847.1 - 4.8e-17 62.2 9.1 4.8e-17 62.2 9.1 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.19 EGE05847.1 - 2e-15 56.8 0.0 7.9e-13 48.3 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 EGE05847.1 - 0.015 13.9 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) HTH_ABP1_N PF18107.1 EGE05847.1 - 1.8 8.3 4.0 1.2 8.9 0.7 2.5 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Slu7 PF11708.8 EGE05848.1 - 3.6e-84 282.7 17.4 3.6e-84 282.7 17.4 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGE05848.1 - 0.019 14.7 0.5 0.042 13.6 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EGE05848.1 - 0.29 11.3 2.8 0.57 10.4 2.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 EGE05848.1 - 1.2 8.9 4.5 2.6 7.8 4.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Ribosomal_L37e PF01907.19 EGE05849.1 - 3.4e-28 97.6 9.0 5.1e-28 97.0 9.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EGE05849.1 - 0.013 15.5 0.9 0.021 14.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 EGE05849.1 - 0.18 11.7 2.8 0.33 10.8 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ELP6 PF09807.9 EGE05850.1 - 2.6e-13 50.0 0.0 2.9e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 EGE05850.1 - 0.12 11.7 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 KaiC RdRP PF05183.12 EGE05851.1 - 1.8e-179 598.1 1.3 3.2e-119 399.2 0.1 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase RRM_1 PF00076.22 EGE05851.1 - 0.0022 17.8 0.0 0.0073 16.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mur_ligase_C PF02875.21 EGE05851.1 - 0.17 12.2 0.1 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain AA_permease PF00324.21 EGE05853.1 - 4.4e-138 460.9 42.0 5.3e-138 460.6 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE05853.1 - 5.4e-37 127.6 45.6 6.6e-37 127.3 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease DDE_Tnp_1_assoc PF13808.6 EGE05853.1 - 0.11 12.5 0.0 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-associated Sulfate_transp PF00916.20 EGE05854.1 - 1.9e-117 392.2 17.8 2.3e-117 392.0 17.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGE05854.1 - 5e-08 32.6 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGE05854.1 - 3.8e-05 24.0 3.4 3.8e-05 24.0 3.4 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily FAD-oxidase_C PF02913.19 EGE05855.1 - 3.4e-48 164.4 0.1 2.6e-45 155.0 0.0 2.2 1 1 1 2 2 2 2 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGE05855.1 - 5.9e-35 120.0 0.1 2e-34 118.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Ribosomal_S4e PF00900.20 EGE05856.1 - 8.7e-37 124.9 0.2 1.8e-36 123.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGE05856.1 - 1.7e-24 85.2 0.0 3e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGE05856.1 - 1.2e-18 66.9 7.0 2.4e-18 66.0 7.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EGE05856.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGE05856.1 - 0.0047 16.8 1.1 0.0047 16.8 1.1 3.1 3 0 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 EGE05856.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Phage tail protein HMG_box PF00505.19 EGE05859.1 - 3.2e-22 78.7 1.0 4.9e-22 78.1 1.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGE05859.1 - 1.6e-07 31.8 0.1 2.8e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos PF03372.23 EGE05861.1 - 2.3e-12 47.0 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EGE05861.1 - 0.001 19.1 0.2 0.0026 17.8 0.2 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.15 EGE05862.1 - 4.4e-52 175.3 1.2 5.3e-52 175.0 1.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANTH PF07651.16 EGE05863.1 - 3.3e-67 226.4 0.0 3.3e-67 226.4 0.0 3.5 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EGE05863.1 - 1.5e-56 190.9 8.3 1.5e-56 190.9 8.3 5.3 3 1 1 5 5 5 1 I/LWEQ domain TcdB_N PF12918.7 EGE05863.1 - 0.061 13.6 5.5 0.12 12.7 2.9 3.1 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain MMM1 PF10296.9 EGE05864.1 - 0.00016 20.9 1.0 0.00034 19.8 0.0 1.9 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EGE05864.1 - 0.68 10.4 2.2 0.76 10.2 0.0 2.2 3 0 0 3 3 3 0 Pleckstrin homology domain Hemerythrin PF01814.23 EGE05865.1 - 6e-13 49.6 0.2 8.5e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MATalpha_HMGbox PF04769.12 EGE05865.1 - 0.045 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box SKG6 PF08693.10 EGE05866.1 - 0.00055 19.3 0.2 0.001 18.4 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.6 EGE05866.1 - 0.046 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Mid2 PF04478.12 EGE05866.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Med12 PF09497.10 EGE05867.1 - 9.9e-29 99.4 0.1 3.7e-28 97.6 0.1 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Kv2channel PF03521.14 EGE05867.1 - 0.0098 15.3 3.2 0.016 14.6 3.2 1.3 1 0 0 1 1 1 1 Kv2 voltage-gated K+ channel Med12-LCEWAV PF12145.8 EGE05867.1 - 0.019 13.9 0.1 0.074 11.9 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic Mediator 12 subunit domain CIA30 PF08547.12 EGE05868.1 - 3.5e-39 134.4 0.0 3.7e-25 88.8 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.18 EGE05869.1 - 2.7e-76 256.5 0.0 3.6e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Collectrin PF16959.5 EGE05869.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter ANAPC5 PF12862.7 EGE05870.1 - 2e-32 111.1 2.7 2.2e-32 111.0 0.9 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EGE05870.1 - 9.5e-05 22.6 6.6 0.47 10.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE05870.1 - 0.00083 19.8 0.8 0.3 11.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGE05870.1 - 0.0068 17.0 0.9 4.8 7.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE05870.1 - 0.021 14.2 0.0 0.058 12.8 0.0 1.7 1 0 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 EGE05870.1 - 0.033 14.2 0.1 8.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGE05870.1 - 0.033 14.3 0.2 23 5.4 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGE05870.1 - 0.065 13.1 0.2 10 6.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE05870.1 - 0.13 13.0 4.0 14 6.7 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Mto2_bdg PF12808.7 EGE05870.1 - 0.18 12.1 1.1 0.41 11.0 1.1 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SUI1 PF01253.22 EGE05871.1 - 4.3e-28 97.7 3.9 5.6e-28 97.3 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EGE05871.1 - 0.084 13.1 0.4 0.13 12.5 0.4 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain EOS1 PF12326.8 EGE05872.1 - 4.9e-11 42.9 12.2 7.7e-11 42.2 9.7 2.0 2 0 0 2 2 2 1 N-glycosylation protein MBA1 PF07961.11 EGE05874.1 - 3.9e-08 32.6 0.1 7.7e-08 31.7 0.1 1.4 1 1 0 1 1 1 1 MBA1-like protein SSF PF00474.17 EGE05875.1 - 1.4e-07 30.7 26.9 8.4e-07 28.2 26.9 2.1 1 1 0 1 1 1 1 Sodium:solute symporter family RhoGAP PF00620.27 EGE05876.1 - 4e-48 163.1 0.0 9.5e-48 161.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGE05876.1 - 3.9e-13 49.5 5.1 6.7e-13 48.7 0.7 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Sigma70_ner PF04546.13 EGE05876.1 - 0.1 12.5 3.0 0.19 11.6 3.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region OmpH PF03938.14 EGE05876.1 - 1.7 9.0 16.1 16 5.8 15.0 2.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ABM PF03992.16 EGE05877.1 - 3.7e-14 52.6 0.0 4.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ras PF00071.22 EGE05878.1 - 8.8e-55 184.7 0.0 1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE05878.1 - 5e-21 75.1 0.0 8.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE05878.1 - 6.5e-07 29.0 0.0 8.2e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Aminotran_1_2 PF00155.21 EGE05880.1 - 4.6e-16 58.9 0.0 8.8e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGE05880.1 - 0.21 10.3 0.0 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.7 EGE05882.1 - 2.4e-100 334.8 13.8 6.8e-85 284.3 6.9 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EGE05882.1 - 5.7e-07 29.1 3.9 0.00046 19.8 0.1 3.0 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Fungal_trans_2 PF11951.8 EGE05885.1 - 5.2e-08 32.1 0.0 1.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05885.1 - 3e-07 30.4 10.0 6.3e-07 29.4 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 EGE05889.1 - 1.9e-27 96.2 0.0 7.8e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE05889.1 - 0.0059 17.1 0.1 0.052 14.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE05889.1 - 0.091 12.8 0.2 1.2 9.1 0.0 2.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding DUF5412 PF17428.2 EGE05889.1 - 0.096 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5412) GAT PF03127.14 EGE05890.1 - 2.2e-20 72.7 1.0 3.4e-20 72.1 0.3 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EGE05890.1 - 0.038 13.8 0.3 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 VHS domain Ferric_reduct PF01794.19 EGE05891.1 - 3.2e-26 91.9 7.7 3.2e-26 91.9 7.7 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGE05891.1 - 2.3e-09 37.3 0.0 6.5e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 EGE05891.1 - 0.0068 16.5 0.1 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Cation_ATPase_C PF00689.21 EGE05891.1 - 0.98 9.1 7.7 29 4.3 7.7 2.2 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus adh_short PF00106.25 EGE05892.1 - 9.4e-54 181.8 0.5 1.3e-53 181.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05892.1 - 2.8e-51 174.3 0.7 3.8e-51 173.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05892.1 - 5.8e-12 45.9 1.3 8.3e-12 45.4 1.3 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE05892.1 - 1.8e-05 24.3 0.3 2.7e-05 23.8 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE05892.1 - 0.00012 21.6 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EGE05892.1 - 0.0066 15.8 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_5 PF08323.11 EGE05892.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 EGE05892.1 - 0.029 14.8 0.2 4.3 7.8 0.0 2.6 2 1 0 3 3 3 0 Glycosyl transferase 4-like domain ApbA PF02558.16 EGE05892.1 - 0.047 13.3 0.2 0.1 12.3 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.18 EGE05894.1 - 4.6e-09 35.7 0.0 1.3e-07 31.0 0.0 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05894.1 - 3.8e-06 26.9 11.1 7.1e-06 26.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EGE05895.1 - 1.6e-44 151.8 0.7 2e-44 151.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05895.1 - 1.9e-43 148.7 0.5 2.2e-43 148.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05895.1 - 3.6e-09 36.8 0.5 5.2e-09 36.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE05895.1 - 0.00095 18.7 0.1 0.0052 16.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGE05895.1 - 0.004 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGE05895.1 - 0.0063 16.4 0.2 0.022 14.6 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGE05895.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 EGE05896.1 - 1.9e-26 92.1 0.1 3.2e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE05896.1 - 4e-12 46.2 0.0 7.8e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGE05896.1 - 6.9e-08 32.2 0.2 0.011 15.2 0.2 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EGE05896.1 - 0.049 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EGE05896.1 - 0.051 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGE05896.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 EGE05896.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EGE05896.1 - 0.19 12.1 0.0 0.95 9.8 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGE05897.1 - 9.5e-56 188.0 0.0 1.3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE05897.1 - 7.5e-18 64.5 0.0 9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGE05897.1 - 0.0033 17.6 0.1 0.0071 16.5 0.1 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EGE05897.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.19 EGE05898.1 - 2.8e-40 136.7 0.1 3.7e-40 136.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Dioxygenase_C PF00775.21 EGE05899.1 - 4.4e-43 146.8 0.0 6.2e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EGE05899.1 - 6.7e-31 106.0 0.0 4.8e-30 103.2 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EGE05899.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.18 EGE05900.1 - 0.65 10.2 11.9 1.8 8.8 11.9 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_N PF01346.18 EGE05900.1 - 0.99 10.4 6.4 0.86 10.6 2.6 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LSM PF01423.22 EGE05902.1 - 3e-20 71.7 1.0 3.9e-20 71.3 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE05902.1 - 0.028 14.6 0.1 0.047 13.8 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF150_C PF17384.2 EGE05902.1 - 0.032 14.4 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF4175 PF13779.6 EGE05902.1 - 4.1 5.2 10.3 4.6 5.0 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pan3_PK PF18101.1 EGE05903.1 - 2.3e-62 209.0 0.4 3.6e-62 208.4 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGE05903.1 - 7.4e-05 22.2 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.6 EGE05904.1 - 2.2e-11 43.4 0.0 4.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGE05904.1 - 1.4e-08 34.8 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain CTP_transf_like PF01467.26 EGE05904.1 - 0.072 13.3 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like AAR2 PF05282.11 EGE05904.1 - 0.1 12.0 5.2 0.16 11.4 5.2 1.2 1 0 0 1 1 1 0 AAR2 protein RR_TM4-6 PF06459.12 EGE05904.1 - 0.27 11.0 5.2 0.53 10.1 5.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1682 PF07946.14 EGE05904.1 - 1.8 7.7 11.9 3.1 6.9 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Presenilin PF01080.17 EGE05904.1 - 7.5 5.2 7.9 12 4.6 7.9 1.2 1 0 0 1 1 1 0 Presenilin PALP PF00291.25 EGE05905.1 - 1e-57 195.8 0.2 1.9e-57 195.0 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 EGE05905.1 - 7.2e-24 84.6 0.1 2.5e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGE05905.1 - 1.9e-19 69.6 0.0 6e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGE05905.1 - 0.00023 20.9 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGE05905.1 - 0.0024 16.9 0.0 4.3 6.3 0.0 3.1 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Vps39_2 PF10367.9 EGE05906.1 - 4.5e-08 33.5 0.1 1.4e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGE05906.1 - 0.17 11.5 0.0 22 4.6 0.0 2.4 2 0 0 2 2 2 0 CNH domain CASP_C PF08172.12 EGE05907.1 - 1.4e-89 299.8 0.2 1.4e-89 299.8 0.2 3.4 3 1 0 3 3 3 1 CASP C terminal HTH_Crp_2 PF13545.6 EGE05907.1 - 0.091 12.8 0.8 0.29 11.1 0.8 1.9 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF3455 PF11937.8 EGE05908.1 - 1.9e-42 145.3 0.0 2.4e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EGE05908.1 - 0.00037 20.6 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 EGE05909.1 - 1.7e-104 347.9 0.0 2.1e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGE05909.1 - 6.4e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EGE05909.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EGE05909.1 - 0.046 13.5 0.1 0.073 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.21 EGE05910.1 - 1.3e-19 70.7 0.0 1.6e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE05910.1 - 1.2e-12 47.9 0.0 3.9e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGE05910.1 - 1.6e-09 37.2 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGE05910.1 - 0.00029 20.1 0.2 0.46 9.6 0.2 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGE05910.1 - 0.00063 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGE05910.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EGE05910.1 - 0.0066 15.9 0.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGE05910.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 EGE05910.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Nitroreductase PF00881.24 EGE05911.1 - 4e-16 59.5 0.0 4.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Phosphoesterase PF04185.14 EGE05911.1 - 0.015 14.5 0.1 0.033 13.4 0.0 1.5 1 1 1 2 2 2 0 Phosphoesterase family MFS_1 PF07690.16 EGE05912.1 - 1.9e-32 112.6 44.8 5.9e-32 110.9 44.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M16 PF00675.20 EGE05913.1 - 7.8e-55 185.0 0.0 3.1e-54 183.0 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGE05913.1 - 2.2e-39 135.4 0.0 4.6e-38 131.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain REV PF00424.18 EGE05914.1 - 0.012 15.7 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) ADH_zinc_N PF00107.26 EGE05915.1 - 1.5e-21 76.8 0.0 2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGE05915.1 - 7.3e-17 61.2 0.1 1.5e-16 60.2 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGE05915.1 - 1.8e-11 45.2 0.0 3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.12 EGE05916.1 - 1.7e-50 170.1 0.0 2.1e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 EGE05917.1 - 1.1e-45 155.4 0.0 1.4e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HNH_2 PF13391.6 EGE05918.1 - 1.8e-15 56.8 0.0 3.8e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HLH PF00010.26 EGE05919.1 - 3.8e-09 36.3 0.1 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.12 EGE05919.1 - 0.014 14.1 1.9 0.016 13.9 1.9 1.0 1 0 0 1 1 1 0 Hamartin protein GFA PF04828.14 EGE05920.1 - 0.055 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L30 PF00327.20 EGE05920.1 - 0.18 11.7 0.0 0.65 9.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Ribonuc_L-PSP PF01042.21 EGE05922.1 - 6.9e-38 129.4 0.0 7.9e-38 129.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Helicase_C PF00271.31 EGE05923.1 - 2.5e-23 82.5 0.0 4.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alpha-amylase PF00128.24 EGE05924.1 - 2.2e-25 89.9 0.2 5.6e-25 88.6 0.2 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EGE05924.1 - 2.3e-05 22.8 1.5 0.0047 15.2 0.0 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EGE05924.1 - 0.064 13.4 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) MFS_1 PF07690.16 EGE05926.1 - 6.1e-45 153.7 35.8 6.1e-45 153.7 35.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05926.1 - 9.3e-14 51.1 5.9 2.1e-13 49.9 5.9 1.6 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGE05926.1 - 5e-05 21.9 1.1 5e-05 21.9 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EGE05926.1 - 0.00056 19.3 5.0 0.00056 19.3 5.0 2.9 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB Vps55 PF04133.14 EGE05926.1 - 0.017 15.1 0.6 0.017 15.1 0.6 2.9 3 0 0 3 3 3 0 Vacuolar protein sorting 55 DUF697 PF05128.12 EGE05926.1 - 2.3 7.9 4.6 8.4 6.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF697) But2 PF09792.9 EGE05927.1 - 0.0081 16.6 0.0 0.041 14.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Fungal_trans PF04082.18 EGE05929.1 - 2.4e-20 72.7 0.0 9.2e-19 67.5 0.0 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05929.1 - 3.6e-07 30.2 8.0 3.6e-07 30.2 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF790 PF05626.11 EGE05930.1 - 0.068 11.9 0.2 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Fe-S_assembly PF04384.13 EGE05931.1 - 0.023 15.3 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 Iron-sulphur cluster assembly GDPD PF03009.17 EGE05932.1 - 4.7e-55 187.1 0.0 1e-54 186.0 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EGE05932.1 - 3.7e-13 49.9 0.1 2.3e-05 24.9 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE05932.1 - 1.3e-09 38.4 0.4 7.7e-05 23.2 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE05932.1 - 9.2e-07 28.7 0.1 0.19 12.4 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EGE05932.1 - 1e-05 25.8 0.0 0.0034 17.8 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGE05932.1 - 8.3e-05 22.8 0.0 0.027 14.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SPX PF03105.19 EGE05932.1 - 0.041 13.8 1.9 0.052 13.5 0.0 2.0 3 0 0 3 3 3 0 SPX domain ATPgrasp_N PF18130.1 EGE05934.1 - 4e-07 30.5 0.0 7.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 EGE05934.1 - 0.00015 21.3 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 EGE05934.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGE05934.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Cytochrome-c551 PF10643.9 EGE05934.1 - 0.16 11.6 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 tRNA-synt_1c PF00749.21 EGE05937.1 - 8.6e-98 327.1 0.0 1.2e-97 326.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGE05937.1 - 2.2e-29 102.5 0.0 6.1e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF1100 PF06500.11 EGE05938.1 - 0.045 12.6 0.8 0.07 11.9 0.8 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) MFS_1 PF07690.16 EGE05939.1 - 3.8e-30 105.0 57.6 2.6e-28 99.0 56.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE05939.1 - 1.9e-07 30.3 12.6 1.9e-07 30.3 12.6 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter SpoVS PF04232.12 EGE05939.1 - 4.2 7.2 9.4 4.7 7.0 1.8 2.7 2 1 0 2 2 2 0 Stage V sporulation protein S (SpoVS) HSP70 PF00012.20 EGE05940.1 - 1.2e-51 175.6 15.8 6.6e-47 160.0 2.2 3.6 4 0 0 4 4 4 3 Hsp70 protein DUF4296 PF14129.6 EGE05940.1 - 0.069 13.8 0.5 0.63 10.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Tubulin_3 PF14881.6 EGE05944.1 - 3.4e-82 274.5 0.1 5.6e-82 273.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EGE05944.1 - 3.4e-23 82.2 0.0 9.5e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EGE05944.1 - 0.0027 17.9 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Spc7 PF08317.11 EGE05945.1 - 0.59 9.0 19.8 1.1 8.0 19.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DinB_2 PF12867.7 EGE05945.1 - 0.59 10.6 3.9 4 8.0 0.1 2.8 2 1 0 2 2 2 0 DinB superfamily FapA PF03961.13 EGE05945.1 - 1.7 7.1 7.6 2.9 6.4 7.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Pet100 PF09803.9 EGE05945.1 - 8.1 7.0 5.6 2.7 8.6 0.7 2.6 1 1 1 2 2 2 0 Pet100 DUF2347 PF09804.9 EGE05946.1 - 7e-102 340.8 0.0 1.2e-101 340.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EGE05946.1 - 4.9e-62 209.7 2.0 7e-62 209.2 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EGE05946.1 - 4.1e-07 29.0 0.0 0.0013 17.5 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EGE05946.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Homez PF11569.8 EGE05946.1 - 0.12 11.9 0.1 0.34 10.4 0.1 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EBP PF05241.12 EGE05947.1 - 5.5e-59 198.6 10.8 6.5e-59 198.4 10.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.23 EGE05948.1 - 3.1e-64 216.9 0.0 4.5e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE05948.1 - 5.5e-15 55.7 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE05948.1 - 4.3e-10 39.9 0.0 1.3e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGE05948.1 - 0.0077 15.4 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SpoIIIAH PF12685.7 EGE05948.1 - 0.21 11.4 5.9 0.49 10.2 5.9 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein AAA_2 PF07724.14 EGE05949.1 - 1.7e-44 151.9 0.0 1.1e-42 146.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGE05949.1 - 1.9e-32 111.3 8.0 2e-32 111.2 1.4 3.8 3 1 1 4 4 3 1 AAA lid domain AAA PF00004.29 EGE05949.1 - 3e-26 92.4 0.0 1.9e-14 54.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGE05949.1 - 1.7e-22 79.3 0.1 6.5e-22 77.4 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGE05949.1 - 1.4e-14 54.3 1.0 1e-07 32.0 0.0 4.0 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGE05949.1 - 7.7e-14 52.4 0.6 6.6e-07 29.9 0.1 4.1 3 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EGE05949.1 - 6e-12 46.0 1.2 0.00041 20.6 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EGE05949.1 - 3.8e-09 36.5 0.0 4.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 EGE05949.1 - 3.8e-07 30.1 4.3 0.0067 16.5 0.1 4.2 3 1 0 3 3 2 2 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 EGE05949.1 - 6.6e-07 29.0 0.0 0.0093 15.5 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 EGE05949.1 - 7.1e-07 28.8 2.0 0.21 11.0 0.0 5.2 5 1 1 6 6 5 2 Bacterial TniB protein IstB_IS21 PF01695.17 EGE05949.1 - 2.8e-06 27.2 0.0 0.094 12.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EGE05949.1 - 5.8e-06 26.9 0.1 0.12 13.0 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EGE05949.1 - 6.6e-06 26.2 0.0 0.11 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGE05949.1 - 1.1e-05 25.6 0.0 0.27 11.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGE05949.1 - 3.8e-05 23.2 0.0 0.15 11.4 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGE05949.1 - 3.9e-05 24.0 0.0 0.54 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EGE05949.1 - 4.6e-05 23.7 0.8 1.3 9.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 EGE05949.1 - 7.5e-05 22.8 6.5 0.32 10.9 0.1 4.6 5 1 0 5 5 4 2 ATPase domain predominantly from Archaea RuvB_N PF05496.12 EGE05949.1 - 9.5e-05 22.2 2.0 2.4 7.9 1.8 4.4 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGE05949.1 - 0.00013 22.0 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGE05949.1 - 0.00016 21.5 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGE05949.1 - 0.00032 20.5 0.0 0.56 9.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 EGE05949.1 - 0.00046 20.7 0.2 1.2 9.7 0.0 3.3 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.6 EGE05949.1 - 0.00058 20.4 9.5 0.22 12.0 0.0 4.8 5 0 0 5 5 5 1 AAA domain RsgA_GTPase PF03193.16 EGE05949.1 - 0.0006 19.8 0.0 0.82 9.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EGE05949.1 - 0.0007 19.4 0.0 0.63 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 EGE05949.1 - 0.0016 18.6 0.0 0.0058 16.7 0.0 1.8 2 0 0 2 2 1 1 Torsin NTPase_1 PF03266.15 EGE05949.1 - 0.0024 17.8 0.2 0.1 12.5 0.0 3.3 3 0 0 3 3 3 1 NTPase AAA_19 PF13245.6 EGE05949.1 - 0.003 17.9 0.2 0.82 10.0 0.1 3.2 2 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EGE05949.1 - 0.0061 16.3 0.0 6.9 6.5 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EGE05949.1 - 0.0063 16.4 0.0 0.37 10.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain T2SSE PF00437.20 EGE05949.1 - 0.0066 15.5 0.0 0.066 12.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 EGE05949.1 - 0.0084 16.3 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EGE05949.1 - 0.0092 15.9 0.0 7.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EGE05949.1 - 0.0097 15.5 0.1 1.6 8.4 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGE05949.1 - 0.012 15.2 0.1 1.6 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGE05949.1 - 0.013 14.8 0.0 5.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 EGE05949.1 - 0.021 14.9 0.0 3 7.8 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 EGE05949.1 - 0.043 13.9 0.7 2.5 8.2 0.2 3.6 3 1 0 3 3 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGE05949.1 - 0.14 11.9 0.1 19 5.0 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein FRQ PF09421.10 EGE05949.1 - 0.28 9.1 3.7 0.53 8.2 3.7 1.3 1 0 0 1 1 1 0 Frequency clock protein KfrA_N PF11740.8 EGE05949.1 - 9.4 6.9 14.5 2.4 8.8 0.1 3.3 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term V-set_2 PF15910.5 EGE05951.1 - 0.046 13.8 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 ICOS V-set domain Deltameth_res PF16020.5 EGE05952.1 - 0.016 15.0 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 Deltamethrin resistance Sulfotransfer_3 PF13469.6 EGE05953.1 - 0.0066 16.8 0.1 2.6 8.4 0.0 2.8 1 1 1 2 2 2 2 Sulfotransferase family KAAG1 PF15354.6 EGE05953.1 - 0.072 13.6 3.6 0.094 13.3 1.8 2.1 2 1 1 3 3 3 0 Kidney-associated antigen 1 UBA2_C PF16195.5 EGE05953.1 - 0.93 10.2 3.1 0.88 10.3 0.3 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus ATG27 PF09451.10 EGE05954.1 - 9.8e-84 281.3 0.0 1.2e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EGE05954.1 - 0.0003 20.9 0.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF1242 PF06842.12 EGE05954.1 - 0.029 14.2 1.0 0.16 11.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1242) SRP9-21 PF05486.12 EGE05954.1 - 0.1 13.0 1.1 0.2 12.1 1.1 1.4 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Prefoldin_2 PF01920.20 EGE05955.1 - 1.3e-22 79.7 3.9 1.6e-22 79.4 3.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Osmo_CC PF08946.10 EGE05955.1 - 0.037 14.3 2.6 0.098 12.9 2.6 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil GPS2_interact PF15784.5 EGE05955.1 - 0.041 14.3 0.4 0.041 14.3 0.4 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF3338 PF11819.8 EGE05955.1 - 0.077 13.0 6.6 1.3 9.0 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) LPP PF04728.13 EGE05955.1 - 0.11 13.0 0.1 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Syntaxin-6_N PF09177.11 EGE05955.1 - 0.2 12.3 5.1 2.4 8.8 5.1 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EGE05955.1 - 0.43 10.6 2.0 1.9 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EGE05955.1 - 0.64 10.3 5.8 1.4 9.2 0.4 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 EGE05955.1 - 0.66 10.2 9.7 0.71 10.1 0.6 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EGE05955.1 - 1.2 9.6 18.0 0.87 10.1 1.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 EGE05955.1 - 1.2 8.4 11.5 6.2 6.1 0.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 EGE05955.1 - 1.7 8.8 12.4 0.11 12.6 2.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor Spc7 PF08317.11 EGE05955.1 - 2.7 6.8 10.8 0.92 8.3 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 EGE05955.1 - 2.8 8.4 9.3 1.4 9.4 0.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 EGE05955.1 - 6.1 6.7 12.0 2.8 7.8 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Fungal_trans PF04082.18 EGE05956.1 - 8.9e-20 70.8 0.4 1.6e-19 70.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE05956.1 - 2.2e-05 24.5 12.8 2.2e-05 24.5 12.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DVL PF08137.12 EGE05956.1 - 6.4 6.7 6.4 20 5.2 6.4 1.9 1 0 0 1 1 1 0 DVL family PAC4 PF16093.5 EGE05957.1 - 2e-25 88.8 0.5 2.8e-25 88.3 0.5 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 EGE05959.1 - 2.1e-87 292.8 0.0 3.4e-87 292.1 0.0 1.3 1 1 0 1 1 1 1 N2227-like protein SelP_N PF04592.14 EGE05959.1 - 1.1 8.6 5.5 2.7 7.3 5.5 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP70 PF00012.20 EGE05960.1 - 2e-10 39.5 0.1 5e-09 34.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EGE05960.1 - 0.095 11.5 0.0 0.3 9.9 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein DUF3445 PF11927.8 EGE05963.1 - 4.5e-63 212.9 0.0 6.1e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Lipase_GDSL_3 PF14606.6 EGE05963.1 - 0.085 13.0 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF1917 PF08939.10 EGE05963.1 - 0.13 12.1 4.9 3.2 7.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1917) 4HBT_3 PF13622.6 EGE05964.1 - 3.2e-78 263.4 0.6 3.9e-78 263.2 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EGE05964.1 - 7.1e-25 87.4 0.0 1.6e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Pkinase PF00069.25 EGE05965.1 - 1.8e-11 43.9 0.0 4.3e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05965.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase 5_nucleotid_C PF02872.18 EGE05966.1 - 0.003 17.8 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain DmpG_comm PF07836.11 EGE05966.1 - 0.061 12.9 0.0 0.72 9.4 0.0 2.3 2 0 0 2 2 2 0 DmpG-like communication domain Pkinase PF00069.25 EGE05967.1 - 3e-10 39.9 0.0 7.4e-07 28.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE05967.1 - 0.11 11.7 0.2 2.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.22 EGE05968.1 - 8.6e-65 219.3 0.0 1e-64 219.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Smim3 PF17307.2 EGE05968.1 - 0.14 11.7 0.5 0.25 10.9 0.5 1.3 1 0 0 1 1 1 0 Small integral membrane protein 3 Methyltransf_23 PF13489.6 EGE05969.1 - 2.2e-17 63.4 0.0 3e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE05969.1 - 8e-13 48.9 0.0 1.9e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE05969.1 - 4.8e-08 33.7 0.0 3.3e-07 31.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE05969.1 - 8.1e-08 32.8 0.0 1.7e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE05969.1 - 3.5e-07 30.1 0.0 3.9e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE05969.1 - 0.00058 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGE05969.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EGE05969.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 EGE05969.1 - 0.014 14.7 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EGE05969.1 - 0.016 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGE05969.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EGE05969.1 - 0.078 12.4 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Ribosomal_S7 PF00177.21 EGE05970.1 - 4.2e-37 127.1 1.7 5.2e-37 126.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 EGE05971.1 - 1.3e-88 297.7 55.6 2.6e-88 296.8 48.9 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EGE05971.1 - 3.7e-23 81.6 0.0 1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.10 EGE05972.1 - 2.5e-25 89.8 1.0 5.2e-25 88.8 0.1 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Carb_anhydrase PF00194.21 EGE05973.1 - 6.7e-33 114.3 0.0 1.4e-32 113.2 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 EGE05973.1 - 0.58 10.1 2.3 0.92 9.4 0.6 2.1 2 1 0 2 2 2 0 Putative carbonic anhydrase AMP-binding PF00501.28 EGE05974.1 - 1e-64 218.8 0.1 9.5e-37 126.6 0.0 4.5 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EGE05974.1 - 2.4e-09 38.0 0.0 7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EGE05974.1 - 0.0089 16.0 0.3 0.02 14.9 0.3 1.6 1 0 0 1 1 1 1 Gas vesicle protein G HMGL-like PF00682.19 EGE05975.1 - 6e-80 268.6 0.0 9.5e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EGE05975.1 - 8.2e-21 74.3 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.29 EGE05976.1 - 2.2e-34 118.8 0.0 4.5e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DHHW PF14286.6 EGE05976.1 - 4.5 6.5 0.0 4.5 6.5 0.0 3.3 3 1 0 3 3 3 0 DHHW protein Acetyltransf_1 PF00583.25 EGE05977.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Arf PF00025.21 EGE05978.1 - 6.7e-63 211.3 0.7 7.5e-63 211.1 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGE05978.1 - 2.9e-11 43.2 3.0 1.9e-06 27.3 0.9 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGE05978.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGE05978.1 - 2.1e-09 37.2 0.0 2.4e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGE05978.1 - 4.3e-09 36.1 0.0 5.2e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGE05978.1 - 8.5e-07 29.1 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGE05978.1 - 4.7e-05 22.9 0.0 6.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGE05978.1 - 0.00031 20.3 0.0 0.0041 16.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.17 EGE05978.1 - 0.0055 15.4 0.0 0.0066 15.2 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 FeoB_N PF02421.18 EGE05978.1 - 0.016 14.7 0.2 0.05 13.1 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4045 PF13254.6 EGE05979.1 - 2.8e-84 284.2 45.2 2.8e-84 284.2 45.2 5.1 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EGE05979.1 - 3.9e-11 42.7 0.0 0.0038 17.1 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 EGE05980.1 - 2.7e-91 306.0 0.1 4.3e-91 305.3 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EGE05980.1 - 1.2e-31 109.3 0.1 2e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 EGE05981.1 - 6.1e-09 35.9 11.8 1.7e-08 34.5 11.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4568 PF15132.6 EGE05981.1 - 0.042 13.2 1.5 0.082 12.3 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) adh_short PF00106.25 EGE05982.1 - 1e-17 64.2 0.0 4e-16 59.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGE05982.1 - 9.7e-10 38.4 0.0 6.3e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE05982.1 - 3.8e-08 33.5 0.0 6.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 EGE05983.1 - 2.2e-10 40.5 10.4 2.2e-10 40.5 10.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE05983.1 - 1.2e-06 27.7 0.1 2.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1_2 PF13684.6 EGE05983.1 - 0.22 10.5 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family PDEase_II PF02112.15 EGE05984.1 - 1.9e-55 188.3 0.0 1.8e-26 93.0 0.0 3.0 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EGE05984.1 - 0.00098 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGE05984.1 - 0.0025 17.9 0.1 0.0053 16.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SPRY PF00622.28 EGE05985.1 - 1.1e-14 54.5 0.7 4.1e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 SPRY domain TFIIA PF03153.13 EGE05985.1 - 0.00017 21.7 20.6 0.00017 21.7 20.6 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 EGE05985.1 - 0.0015 17.6 13.9 0.0015 17.6 13.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TMEM51 PF15345.6 EGE05985.1 - 0.051 13.4 11.7 0.54 10.1 5.0 3.6 3 0 0 3 3 3 0 Transmembrane protein 51 DUF3611 PF12263.8 EGE05985.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DDHD PF02862.17 EGE05985.1 - 0.4 10.8 8.3 0.77 9.9 6.4 2.1 2 0 0 2 2 2 0 DDHD domain DUF3506 PF12014.8 EGE05985.1 - 0.45 10.5 5.2 0.93 9.5 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) MCU PF04678.13 EGE05985.1 - 0.8 9.8 7.5 2.1 8.4 7.5 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4199 PF13858.6 EGE05985.1 - 1.6 9.1 5.2 6 7.2 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) UPF0560 PF10577.9 EGE05985.1 - 3.9 5.9 16.7 7.9 4.8 16.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.12 EGE05985.1 - 6.6 5.6 14.6 10 5.0 14.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NST1 PF13945.6 EGE05985.1 - 8.3 6.5 17.7 0.91 9.6 8.5 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator Peptidase_M24 PF00557.24 EGE05988.1 - 3.5e-52 177.2 0.0 4.5e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGE05988.1 - 4.3e-18 65.2 0.0 8.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain NAD_binding_8 PF13450.6 EGE05988.1 - 0.028 14.6 0.0 5.7 7.3 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.31 EGE05990.1 - 2.4e-16 59.6 0.6 6.3e-16 58.3 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EGE05990.1 - 1.3e-13 50.8 0.0 1.7e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DTHCT PF08070.11 EGE05990.1 - 3.1 8.6 9.1 3.7 8.3 3.6 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region Amidase PF01425.21 EGE05991.1 - 5.8e-78 262.8 0.1 2e-77 261.1 0.1 1.7 1 1 0 1 1 1 1 Amidase GWT1 PF06423.12 EGE05992.1 - 2.3e-34 118.7 5.2 4.8e-34 117.6 2.2 2.6 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EGE05992.1 - 0.016 15.7 1.9 0.53 10.8 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4818) MFS_1 PF07690.16 EGE05995.1 - 1.2e-16 60.6 21.2 1.2e-16 60.6 21.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGE05995.1 - 9.2e-06 24.3 1.0 1.4e-05 23.7 1.0 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.7 EGE05995.1 - 0.016 14.0 0.7 0.016 14.0 0.7 3.1 3 1 1 4 4 4 0 MFS_1 like family Acyl-CoA_dh_1 PF00441.24 EGE05996.1 - 1.7e-37 129.0 5.7 2.7e-37 128.3 5.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGE05996.1 - 4e-30 104.8 0.7 1.3e-29 103.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGE05996.1 - 3.5e-24 84.8 0.0 1.3e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGE05996.1 - 7.6e-14 52.1 1.7 1.5e-13 51.2 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 EGE05996.1 - 0.0064 16.5 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 Staphylococcal AgrD protein HpaB_N PF11794.8 EGE05996.1 - 0.02 14.6 0.0 0.051 13.2 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Stanniocalcin PF03298.13 EGE05997.1 - 3.4e-05 23.2 0.1 3.8e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Stanniocalcin family Senescence PF06911.12 EGE05998.1 - 1.8e-54 184.8 2.1 2.9e-54 184.2 2.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.25 EGE06000.1 - 1.5e-63 214.6 0.0 2.4e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06000.1 - 1.1e-34 120.0 0.0 2.7e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGE06000.1 - 2.7e-06 26.9 0.0 0.00061 19.2 0.0 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGE06000.1 - 0.00042 20.3 0.4 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE06000.1 - 0.0032 17.1 0.2 0.0082 15.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EGE06000.1 - 0.016 14.1 0.2 0.027 13.4 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGE06000.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TSA PF03249.13 EGE06000.1 - 2.8 6.6 5.8 0.79 8.4 1.0 2.1 2 0 0 2 2 2 0 Type specific antigen MMM1 PF10296.9 EGE06002.1 - 1.3e-07 31.0 0.0 3.2e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Bap31 PF05529.12 EGE06003.1 - 2.9e-48 163.2 7.1 3.7e-48 162.8 7.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGE06003.1 - 7.2e-16 57.9 3.8 1.1e-15 57.3 3.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Atg14 PF10186.9 EGE06003.1 - 0.03 13.4 1.3 0.039 13.1 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 EGE06003.1 - 0.032 14.4 0.5 0.057 13.6 0.4 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EGE06003.1 - 0.04 13.7 2.6 0.078 12.8 0.3 2.5 2 1 0 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.13 EGE06003.1 - 0.075 13.5 0.1 0.14 12.6 0.1 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4349 PF14257.6 EGE06003.1 - 0.12 11.8 0.2 0.12 11.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf-C2H2_aberr PF17017.5 EGE06005.1 - 0.00011 22.5 1.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EGE06005.1 - 0.00013 22.5 11.3 0.03 15.1 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE06005.1 - 0.0072 16.7 19.6 0.05 14.1 0.8 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGE06005.1 - 0.014 15.6 0.7 2.8 8.3 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EGE06005.1 - 0.026 14.9 0.5 0.026 14.9 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double domain WXG100 PF06013.12 EGE06005.1 - 0.075 13.3 1.3 0.25 11.6 1.3 1.8 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4719 PF15843.5 EGE06005.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4719) TFIIA PF03153.13 EGE06006.1 - 8.7e-87 292.8 23.2 1.2e-86 292.3 23.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2563 PF10817.8 EGE06006.1 - 0.05 14.2 0.7 0.1 13.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) BOP1NT PF08145.12 EGE06006.1 - 3.2 7.6 12.4 0.4 10.6 5.7 2.2 2 0 0 2 2 2 0 BOP1NT (NUC169) domain DUF1387 PF07139.11 EGE06006.1 - 5.4 6.6 9.7 5.1 6.7 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Na_Ca_ex PF01699.24 EGE06009.1 - 5.8e-30 104.2 36.9 6.5e-15 55.4 12.5 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2721 PF11026.8 EGE06009.1 - 0.55 10.1 0.0 0.55 10.1 0.0 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF2721) FAD_binding_4 PF01565.23 EGE06010.1 - 1.2e-21 77.0 0.0 2.1e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE06010.1 - 0.0096 16.0 0.0 0.034 14.2 0.0 2.0 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EGE06012.1 - 7.9e-36 123.8 0.1 1.1e-35 123.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 EGE06013.1 - 2.2e-10 40.5 0.1 1.6e-09 37.7 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain SEEEED PF14797.6 EGE06013.1 - 3.5 7.8 10.9 0.041 14.0 2.5 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex DUF973 PF06157.11 EGE06014.1 - 0.039 13.0 14.1 0.0091 15.1 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF373 PF04123.13 EGE06014.1 - 9.3 5.6 16.1 6.1 6.2 10.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) ADP_ribosyl_GH PF03747.14 EGE06015.1 - 1.4e-56 192.4 0.0 1.7e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase BcrAD_BadFG PF01869.20 EGE06016.1 - 4.6e-08 32.9 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 EGE06016.1 - 0.12 12.4 0.1 0.4 10.7 0.1 1.9 1 1 0 1 1 1 0 SIS domain MFS_1 PF07690.16 EGE06017.1 - 5e-11 42.1 40.6 5e-11 42.1 40.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGE06017.1 - 1.1e-08 34.9 6.8 1.1e-08 34.9 6.8 3.0 2 2 1 3 3 3 1 Ion channel regulatory protein UNC-93 Bac_export_2 PF01312.19 EGE06017.1 - 7.4 5.7 9.0 0.14 11.3 0.3 2.4 3 0 0 3 3 3 0 FlhB HrpN YscU SpaS Family MFS_1 PF07690.16 EGE06018.1 - 3.5e-33 115.0 30.5 4.9e-33 114.5 30.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06018.1 - 1.5e-09 37.3 11.2 1.5e-09 37.3 11.2 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.11 EGE06019.1 - 7.2e-14 51.6 14.1 1.2e-13 50.9 14.1 1.4 1 0 0 1 1 1 1 CFEM domain Ilm1 PF10311.9 EGE06021.1 - 2.5e-18 66.3 0.0 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Ilm1 PF10311.9 EGE06022.1 - 1.9e-60 203.3 0.3 2.3e-60 203.0 0.3 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF5357 PF17310.2 EGE06022.1 - 0.96 7.9 5.3 11 4.4 5.3 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5357) Prenyltrans PF00432.21 EGE06023.1 - 5.8e-31 105.9 13.2 7.1e-08 32.1 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGE06023.1 - 0.0017 17.5 0.0 0.0099 15.0 0.0 2.2 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGE06023.1 - 0.14 11.2 0.0 8.2 5.4 0.0 3.2 4 1 0 4 4 4 0 Squalene-hopene cyclase N-terminal domain Pkinase PF00069.25 EGE06024.1 - 3.1e-66 223.4 0.0 5e-66 222.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06024.1 - 1.6e-41 142.3 0.0 2.4e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE06024.1 - 1.6e-08 34.2 0.0 2.4e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGE06024.1 - 9.9e-06 24.7 0.0 9.9e-06 24.7 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain PRKG1_interact PF15898.5 EGE06024.1 - 0.018 15.9 2.9 0.059 14.3 2.9 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Kdo PF06293.14 EGE06024.1 - 0.04 13.3 0.0 0.04 13.3 0.0 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferlin_C PF16165.5 EGE06024.1 - 0.27 11.2 0.5 0.48 10.4 0.5 1.3 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 EGE06024.1 - 0.9 9.4 6.9 1.2 9.0 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGE06024.1 - 2.8 7.5 4.3 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 EGE06025.1 - 2.5e-16 59.5 42.4 8.4e-15 54.5 42.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06025.1 - 0.00019 20.5 8.0 0.00019 20.5 8.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter HlyIII PF03006.20 EGE06025.1 - 0.0015 18.3 10.3 0.0062 16.3 0.1 3.3 1 1 1 3 3 3 2 Haemolysin-III related LapA_dom PF06305.11 EGE06025.1 - 0.12 12.2 1.6 1.3 8.9 0.0 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TRIQK PF15168.6 EGE06025.1 - 0.73 9.8 4.5 0.68 9.9 0.2 2.8 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Eisosome1 PF12757.7 EGE06026.1 - 3e-28 98.6 2.7 3e-28 98.6 2.7 2.5 3 0 0 3 3 3 1 Eisosome protein 1 Ysc84 PF04366.12 EGE06026.1 - 0.16 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 Las17-binding protein actin regulator Trypsin_2 PF13365.6 EGE06027.1 - 9.7e-25 88.2 0.0 1.4e-24 87.7 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGE06027.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin DUF1640 PF07798.11 EGE06028.1 - 8.6e-07 29.2 0.1 1.1e-06 28.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PMM PF03332.13 EGE06029.1 - 3.9e-95 317.8 0.0 4.5e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGE06029.1 - 5.1e-05 23.1 0.0 0.00059 19.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.13 EGE06029.1 - 0.039 13.2 0.1 0.053 12.8 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein MFS_1 PF07690.16 EGE06030.1 - 7.5e-40 136.9 50.1 2.1e-39 135.5 50.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TadZ_N PF16968.5 EGE06030.1 - 0.8 9.4 4.1 0.42 10.3 1.3 1.9 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal DnaJ PF00226.31 EGE06032.1 - 2.1e-19 69.4 3.5 3.6e-19 68.6 3.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EGE06032.1 - 0.00099 19.4 2.3 0.0015 18.8 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF2076 PF09849.9 EGE06032.1 - 0.0016 18.5 0.1 0.0023 18.0 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF460 PF04312.13 EGE06032.1 - 0.13 12.0 0.4 0.21 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Bacteriocin_IIc PF10439.9 EGE06032.1 - 0.9 9.7 7.9 1.6 8.9 7.9 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide FAM76 PF16046.5 EGE06033.1 - 1.4 8.2 3.2 1.8 7.9 3.2 1.1 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 EGE06033.1 - 10 4.6 6.7 12 4.3 6.7 1.0 1 0 0 1 1 1 0 Macoilin family MBOAT_2 PF13813.6 EGE06034.1 - 3.4e-17 62.5 4.6 8.4e-17 61.2 4.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_S8 PF00082.22 EGE06036.1 - 2.2e-30 105.9 17.4 2.2e-30 105.9 17.4 1.6 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 EGE06036.1 - 5.3e-16 59.0 0.5 9.1e-16 58.3 0.5 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 E1-E2_ATPase PF00122.20 EGE06037.1 - 3.7e-49 166.7 2.3 3.7e-49 166.7 2.3 3.1 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE06037.1 - 1.2e-45 155.5 5.6 1.2e-45 155.5 5.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGE06037.1 - 2.2e-23 83.6 0.0 6.6e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGE06037.1 - 5.2e-20 70.9 0.2 2.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGE06037.1 - 2.2e-08 34.1 1.5 5.5e-06 26.3 1.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGE06037.1 - 6.5e-07 29.9 0.0 2.5e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase adh_short PF00106.25 EGE06038.1 - 1.9e-17 63.4 0.0 3.3e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE06038.1 - 9.5e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE06038.1 - 0.00043 20.3 0.0 0.00067 19.6 0.0 1.3 1 0 0 1 1 1 1 KR domain 14-3-3 PF00244.20 EGE06039.1 - 6.4e-107 356.1 3.6 8e-107 355.8 3.6 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF4164 PF13747.6 EGE06039.1 - 0.11 12.7 2.0 0.41 11.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Peptidase_C98 PF15499.6 EGE06039.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ima1_N PF09779.9 EGE06039.1 - 0.29 12.0 2.8 2.1 9.2 0.0 3.2 4 0 0 4 4 4 0 Ima1 N-terminal domain CENP-B_dimeris PF09026.10 EGE06040.1 - 0.052 13.9 0.6 0.072 13.5 0.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cytomega_UL84 PF06284.11 EGE06040.1 - 0.052 12.0 0.4 0.065 11.7 0.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Ribosomal_60s PF00428.19 EGE06040.1 - 0.11 13.1 7.3 0.18 12.4 7.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein MDM10 PF12519.8 EGE06040.1 - 0.38 9.6 0.6 0.51 9.1 0.0 1.4 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 eIF3_subunit PF08597.10 EGE06041.1 - 4.3e-51 174.2 44.6 1.1e-27 97.6 31.7 2.0 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit DUF572 PF04502.13 EGE06041.1 - 1.4 8.4 25.4 1.9 8.0 25.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Enolase_C PF00113.22 EGE06042.1 - 1.4e-153 510.4 0.0 1.8e-153 510.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGE06042.1 - 4.4e-57 191.9 0.2 7.5e-57 191.1 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGE06042.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like VSP PF03302.13 EGE06042.1 - 0.13 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF5543 PF17697.1 EGE06043.1 - 0.0025 18.1 0.5 0.0032 17.7 0.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5543) Cation_ATPase_C PF00689.21 EGE06044.1 - 1.8e-43 148.4 3.9 1.8e-43 148.4 3.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGE06044.1 - 1.5e-38 132.1 4.0 9e-38 129.6 1.4 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGE06044.1 - 1.6e-19 71.1 0.0 4.8e-08 33.6 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE06044.1 - 5.7e-18 64.8 0.0 1.2e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGE06044.1 - 2.3e-11 43.2 0.0 4.9e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGE06044.1 - 0.00088 19.1 0.5 0.002 17.9 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGE06044.1 - 0.0048 17.3 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 EGE06044.1 - 3 7.6 6.7 11 5.8 0.9 3.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) AAA PF00004.29 EGE06045.1 - 7.2e-43 146.2 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGE06045.1 - 3.4e-11 42.9 0.0 9.5e-11 41.5 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGE06045.1 - 1.6e-10 40.6 0.1 3e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGE06045.1 - 2.8e-07 31.1 0.0 0.00012 22.5 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGE06045.1 - 1.8e-06 28.0 0.0 4.3e-05 23.5 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGE06045.1 - 2.5e-06 27.7 0.0 8e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGE06045.1 - 6.9e-06 25.9 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE06045.1 - 0.00019 21.8 0.0 0.0031 17.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGE06045.1 - 0.00046 19.4 0.0 0.00096 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGE06045.1 - 0.00051 20.6 0.1 0.0033 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGE06045.1 - 0.00056 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGE06045.1 - 0.0019 17.5 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGE06045.1 - 0.0039 17.3 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EGE06045.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 EGE06045.1 - 0.0048 16.3 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGE06045.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGE06045.1 - 0.0073 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGE06045.1 - 0.0074 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGE06045.1 - 0.0091 15.7 0.0 0.03 14.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGE06045.1 - 0.0093 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGE06045.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGE06045.1 - 0.032 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EGE06045.1 - 0.034 13.9 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGE06045.1 - 0.073 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EGE06045.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EGE06045.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGE06045.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGE06045.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGE06045.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EGE06045.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGE06045.1 - 0.13 12.0 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.20 EGE06046.1 - 3e-164 547.3 0.0 3.6e-164 547.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 M20_dimer PF07687.14 EGE06047.1 - 2.6e-21 75.6 0.0 6.8e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EGE06047.1 - 2.2e-15 57.0 0.1 8e-14 51.8 0.1 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EGE06047.1 - 0.00014 21.0 0.0 0.0013 17.8 0.0 2.4 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EGE06047.1 - 0.025 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF373 PF04123.13 EGE06047.1 - 0.03 13.8 0.3 0.049 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Peptidase_C14 PF00656.22 EGE06047.1 - 0.16 11.9 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Caspase domain HATPase_c PF02518.26 EGE06048.1 - 5.8e-19 68.7 0.0 2e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGE06048.1 - 2.2e-14 53.6 0.5 6.9e-09 35.9 0.1 3.3 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EGE06048.1 - 5.9e-05 23.0 0.1 0.00026 20.9 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGE06048.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L36e PF01158.18 EGE06049.1 - 5.1e-38 129.2 7.1 5.7e-38 129.1 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HTH_38 PF13936.6 EGE06049.1 - 0.0095 15.7 1.6 0.22 11.3 0.1 2.6 2 1 0 2 2 2 1 Helix-turn-helix domain PBS_linker_poly PF00427.21 EGE06049.1 - 0.04 14.0 0.4 0.044 13.8 0.4 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide LemA PF04011.12 EGE06049.1 - 0.13 12.1 0.3 0.16 11.8 0.3 1.2 1 0 0 1 1 1 0 LemA family MRP-L28 PF09812.9 EGE06049.1 - 0.13 12.4 2.6 0.15 12.2 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 DUF2207 PF09972.9 EGE06049.1 - 0.13 11.0 0.1 0.14 10.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4239 PF14023.6 EGE06049.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) TUG-UBL1 PF11470.8 EGE06050.1 - 6.6e-24 83.9 1.3 1.7e-23 82.6 0.1 2.3 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EGE06050.1 - 4.9e-06 26.7 0.1 4.6e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 UBX domain RBD PF02196.15 EGE06050.1 - 0.012 15.7 0.0 0.056 13.5 0.0 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain Proteasome PF00227.26 EGE06051.1 - 5.6e-42 143.4 0.0 6.5e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.9 EGE06052.1 - 9.3e-102 340.8 1.0 1.4e-101 340.2 1.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EGE06052.1 - 3.4e-06 27.5 7.9 0.0058 17.1 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE06052.1 - 2.5 9.2 10.8 72 4.6 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat CHCH PF06747.13 EGE06053.1 - 1.6e-05 24.9 4.2 3.3e-05 23.9 4.0 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 EGE06053.1 - 0.00044 20.4 1.4 0.0006 20.0 1.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 EGE06053.1 - 0.044 14.1 5.2 0.082 13.2 4.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EGE06053.1 - 0.061 13.7 2.6 0.42 11.0 1.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 EGE06053.1 - 0.081 13.2 3.4 0.14 12.5 3.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF2527 PF10736.9 EGE06054.1 - 0.0094 15.8 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2627) zf-C3HC4 PF00097.25 EGE06056.1 - 7.1e-09 35.4 7.7 7.1e-09 35.4 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE06056.1 - 1.6e-08 34.7 8.4 1.6e-08 34.7 8.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGE06056.1 - 2.8e-08 33.5 5.5 2.8e-08 33.5 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE06056.1 - 3.3e-08 33.2 8.8 3.3e-08 33.2 8.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE06056.1 - 3e-07 30.5 10.6 3e-07 30.5 10.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGE06056.1 - 1.7e-06 27.9 9.1 1.7e-06 27.9 9.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGE06056.1 - 4.5e-06 26.5 7.0 4.5e-06 26.5 7.0 2.4 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGE06056.1 - 0.0018 18.1 6.7 0.0018 18.1 6.7 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGE06056.1 - 0.023 15.0 7.9 0.023 15.0 7.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGE06056.1 - 0.026 14.3 3.5 0.026 14.3 3.5 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGE06056.1 - 0.074 13.1 14.6 2 8.5 0.2 3.3 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_11 PF17123.5 EGE06056.1 - 0.32 10.8 4.0 1.3 8.8 4.0 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EGE06056.1 - 0.76 10.0 5.7 1.6 8.9 5.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGE06056.1 - 0.9 9.6 9.7 0.061 13.4 4.1 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC45 PF02724.14 EGE06056.1 - 6 5.0 7.3 8.8 4.5 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EGE06057.1 - 8.2e-20 70.8 12.0 2.5e-05 24.9 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EGE06057.1 - 9.6e-05 21.2 3.0 0.16 10.6 0.0 3.8 1 1 4 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGE06057.1 - 0.0016 18.7 0.0 0.021 15.1 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGE06057.1 - 0.0089 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Nha1_C PF08619.10 EGE06057.1 - 2.1 7.4 12.3 4.6 6.3 12.3 1.5 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Proteasome PF00227.26 EGE06058.1 - 2.7e-30 105.3 0.0 3e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MF_alpha_N PF05436.11 EGE06059.1 - 0.021 14.7 0.4 0.043 13.7 0.4 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Peptidase_C97 PF05903.14 EGE06059.1 - 0.051 13.4 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain Arrestin_N PF00339.29 EGE06059.1 - 0.081 13.0 1.1 0.12 12.4 1.1 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LRRC37AB_C PF14914.6 EGE06059.1 - 0.23 11.4 2.6 0.4 10.6 2.6 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain TLD PF07534.16 EGE06060.1 - 6.3e-11 42.7 0.0 1.2e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 TLD UCH PF00443.29 EGE06061.1 - 1.2e-21 77.4 0.1 3.6e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGE06061.1 - 4.5e-12 46.1 0.3 7.8e-12 45.4 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGE06061.1 - 0.0056 16.3 0.1 0.018 14.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3086 PF11285.8 EGE06062.1 - 0.16 11.1 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) WD40 PF00400.32 EGE06063.1 - 1e-55 184.4 16.4 1e-05 26.2 0.0 14.1 13 3 0 13 13 13 9 WD domain, G-beta repeat Utp13 PF08625.11 EGE06063.1 - 3e-48 163.3 0.1 4.7e-48 162.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGE06063.1 - 5.5e-14 52.2 0.4 1.8 8.9 0.0 8.5 5 1 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE06063.1 - 7.3e-06 24.9 6.5 1.1 7.8 1.3 5.3 3 2 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGE06063.1 - 0.00059 18.7 4.5 0.48 9.1 0.1 4.6 5 1 0 6 6 6 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EGE06063.1 - 0.0015 17.6 3.6 5.7 5.8 0.0 5.4 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 EGE06063.1 - 0.0051 15.5 0.0 0.036 12.7 0.0 2.2 1 1 1 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term G-patch_2 PF12656.7 EGE06064.1 - 1.4e-24 85.9 0.2 5.2e-24 84.1 0.2 2.1 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EGE06064.1 - 0.00018 21.3 0.5 0.00075 19.3 0.5 2.1 1 0 0 1 1 1 1 G-patch domain Myb_DNA-bind_6 PF13921.6 EGE06065.1 - 6.5e-17 61.5 0.1 6.5e-17 61.5 0.1 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 EGE06065.1 - 1e-13 51.4 0.2 1e-13 51.4 0.2 3.3 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EGE06065.1 - 0.00021 21.4 0.4 0.00057 20.0 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 EGE06066.1 - 3.9e-09 37.0 0.0 3.7 8.6 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGE06066.1 - 0.0027 16.5 0.1 1.8 7.2 0.0 2.4 2 1 0 2 2 2 2 Nup133 N terminal like CW_7 PF08230.11 EGE06066.1 - 0.021 14.6 0.3 0.044 13.5 0.3 1.4 1 0 0 1 1 1 0 CW_7 repeat eIF2_C PF09173.11 EGE06067.1 - 3e-34 117.1 0.2 7.2e-34 115.9 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGE06067.1 - 4.7e-23 81.7 0.2 3.4e-22 78.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGE06067.1 - 8.7e-12 45.3 0.2 1.9e-11 44.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EGE06067.1 - 0.0021 18.0 0.1 0.023 14.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGE06067.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L34 PF00468.17 EGE06068.1 - 4.6e-16 58.5 9.6 7.5e-16 57.8 9.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 RNA_polI_A14 PF08203.11 EGE06069.1 - 0.045 14.5 0.1 0.63 10.8 0.0 2.3 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Peptidase_S49_N PF08496.10 EGE06069.1 - 3.1 7.8 7.6 2.7 8.0 6.5 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M48_N PF16491.5 EGE06070.1 - 1.1e-66 224.3 8.9 1.1e-66 224.3 8.9 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGE06070.1 - 1.5e-44 152.1 0.6 2.2e-44 151.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 DUF4538 PF15061.6 EGE06070.1 - 0.01 15.5 1.1 0.03 14.1 1.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Peptidase_M56 PF05569.11 EGE06070.1 - 0.032 13.4 1.9 0.13 11.4 0.5 2.2 2 1 0 2 2 2 0 BlaR1 peptidase M56 Methyltransf_2 PF00891.18 EGE06071.1 - 1.7e-25 89.6 0.0 2.5e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGE06071.1 - 0.0025 18.5 0.0 0.0052 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06071.1 - 0.0037 18.0 0.0 0.0063 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 EGE06072.1 - 6.4e-39 134.3 0.0 1e-38 133.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGE06072.1 - 1e-32 112.6 0.2 2.3e-32 111.5 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EGE06072.1 - 3.1e-26 92.9 0.3 6.9e-25 88.5 0.0 3.3 3 1 0 3 3 3 1 Thioesterase domain PS-DH PF14765.6 EGE06072.1 - 2.9e-14 53.0 0.0 4.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EGE06072.1 - 4.3e-11 43.0 0.6 1.1e-10 41.7 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EGE06072.1 - 5.6e-11 42.5 0.1 9.9e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Abhydrolase_6 PF12697.7 EGE06072.1 - 2.9e-09 37.8 0.4 4.9e-05 24.0 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EGE06072.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 EGE06072.1 - 0.02 14.2 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SAT PF16073.5 EGE06073.1 - 1.9e-68 230.8 0.2 2.6e-68 230.4 0.2 1.2 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EGE06073.1 - 5.2e-36 124.5 0.0 1.1e-35 123.5 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain EthD PF07110.11 EGE06074.1 - 3.8e-19 69.6 0.2 6e-19 69.0 0.2 1.3 1 0 0 1 1 1 1 EthD domain Cu-oxidase_3 PF07732.15 EGE06075.1 - 1.1e-41 141.5 2.3 1.4e-40 138.0 0.6 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE06075.1 - 1.1e-17 64.1 4.4 1.3e-11 44.4 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE06075.1 - 4.7e-16 59.3 0.0 2.2e-13 50.6 0.0 2.7 2 1 0 2 2 2 2 Multicopper oxidase MFS_1 PF07690.16 EGE06076.1 - 1.1e-05 24.6 21.5 2.2e-05 23.5 20.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 EGE06076.1 - 0.04 14.3 3.8 0.081 13.3 3.8 1.4 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 Peptidase_U4 PF03419.13 EGE06076.1 - 4.8 6.4 9.5 4.9 6.4 8.0 1.7 1 1 0 1 1 1 0 Sporulation factor SpoIIGA Fungal_trans PF04082.18 EGE06077.1 - 9.3e-18 64.2 0.2 1.9e-17 63.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06077.1 - 7.3e-06 26.0 9.2 1.5e-05 25.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5447 PF17525.2 EGE06077.1 - 0.11 13.0 0.4 0.32 11.5 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5447) Hydrolase_4 PF12146.8 EGE06078.1 - 6.2e-09 35.5 0.1 8.8e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE06078.1 - 1.2e-08 35.8 0.6 2.1e-08 35.0 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE06078.1 - 0.00022 21.0 0.3 0.00035 20.3 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE06078.1 - 0.016 14.7 0.1 3.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ank_2 PF12796.7 EGE06080.1 - 4.6e-50 168.1 0.1 8.9e-16 58.3 0.0 6.3 5 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE06080.1 - 1.5e-43 146.6 0.8 6.8e-11 42.5 0.1 8.9 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE06080.1 - 1.2e-35 117.5 0.2 0.0026 18.1 0.0 11.9 11 0 0 11 11 11 8 Ankyrin repeat Ank PF00023.30 EGE06080.1 - 5.7e-25 86.6 5.0 0.072 13.6 0.1 11.0 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 EGE06080.1 - 1e-24 86.2 0.5 9.8e-06 25.8 0.0 8.2 4 2 4 8 8 8 7 Ankyrin repeats (many copies) NACHT PF05729.12 EGE06080.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Peptidase_M16_C PF05193.21 EGE06081.1 - 1.1e-16 61.4 0.0 3.2e-15 56.6 0.0 2.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGE06081.1 - 4e-08 33.4 0.0 1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RQC PF09382.10 EGE06081.1 - 0.0076 16.0 0.2 0.25 11.1 0.0 2.7 2 0 0 2 2 2 1 RQC domain SMBP PF16785.5 EGE06081.1 - 0.21 11.8 1.0 0.64 10.2 1.0 1.8 1 0 0 1 1 1 0 Small metal-binding protein RRN3 PF05327.11 EGE06081.1 - 2.3 6.6 6.7 3.9 5.9 6.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zw10 PF06248.13 EGE06082.1 - 5.6e-08 31.8 5.7 2.4e-07 29.7 5.5 1.9 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EGE06082.1 - 2e-06 27.7 0.1 4.4e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal IFT46_B_C PF12317.8 EGE06082.1 - 0.16 11.7 1.8 0.32 10.7 1.8 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal ArAE_1_C PF11728.8 EGE06082.1 - 0.25 11.3 5.6 0.63 10.0 5.6 1.6 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain WD40 PF00400.32 EGE06083.1 - 5.6e-18 65.0 19.3 4e-07 30.6 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 EGE06083.1 - 3.9e-17 62.5 0.1 6.9e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EGE06083.1 - 0.0065 15.2 2.1 0.05 12.3 0.7 2.4 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Ribosomal_S13 PF00416.22 EGE06084.1 - 2.3e-16 60.4 0.0 2.4e-14 53.8 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 EGE06085.1 - 9e-50 169.0 0.3 1.2e-49 168.6 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COesterase PF00135.28 EGE06086.1 - 1.5e-103 347.4 0.0 1.9e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE06086.1 - 4.5e-05 23.4 0.0 0.00011 22.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE06086.1 - 0.0058 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Fungal_trans_2 PF11951.8 EGE06088.1 - 3e-06 26.3 0.0 2.3e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF639 PF04842.12 EGE06088.1 - 0.2 11.1 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DEAD PF00270.29 EGE06089.1 - 7.8e-48 162.6 0.0 3e-47 160.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE06089.1 - 3.4e-32 111.1 0.0 7.7e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE06089.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGE06089.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGE06089.1 - 0.23 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RNase_H2_suC PF08615.11 EGE06090.1 - 0.085 13.0 3.8 0.92 9.7 0.2 3.0 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) INSIG PF07281.12 EGE06091.1 - 3.4e-74 249.1 5.6 5.8e-74 248.3 5.6 1.4 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Clathrin PF00637.20 EGE06093.1 - 6.5e-196 642.1 33.7 7e-33 113.5 0.4 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGE06093.1 - 2.5e-29 101.0 1.7 6.7e-29 99.6 0.3 2.6 2 1 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EGE06093.1 - 1.2e-26 91.7 0.6 1.4e-05 25.1 0.0 5.0 5 0 0 5 5 5 4 Clathrin propeller repeat TPR_14 PF13428.6 EGE06093.1 - 1.9e-05 25.1 6.2 0.3 12.0 0.2 7.7 9 0 0 9 9 7 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EGE06093.1 - 0.0011 18.3 0.1 0.0025 17.2 0.1 1.6 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_8 PF13181.6 EGE06093.1 - 0.016 15.4 3.0 2.8 8.4 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGE06093.1 - 0.049 13.7 6.2 67 3.8 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 EGE06093.1 - 0.11 12.5 0.7 0.46 10.4 0.0 2.5 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB TPR_1 PF00515.28 EGE06093.1 - 0.18 11.7 0.9 31 4.6 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1400 PF07176.11 EGE06093.1 - 1.1 9.5 4.7 10 6.5 0.0 4.4 5 1 0 5 5 5 0 Alpha/beta hydrolase of unknown function (DUF1400) TPR_19 PF14559.6 EGE06093.1 - 5.4 7.6 8.4 50 4.5 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 EGE06095.1 - 1.3e-80 269.9 0.1 2e-80 269.3 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGE06095.1 - 1.1e-39 135.3 0.1 2.4e-39 134.3 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain PYC_OADA PF02436.18 EGE06095.1 - 9.4e-39 133.2 0.0 1.1e-30 106.9 0.0 2.4 2 0 0 2 2 2 2 Conserved carboxylase domain Biotin_carb_C PF02785.19 EGE06095.1 - 1.2e-31 109.0 0.0 3.8e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EGE06095.1 - 2.7e-23 82.9 0.0 5.6e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EGE06095.1 - 4.1e-17 61.8 4.5 4.4e-17 61.7 2.9 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGE06095.1 - 5.2e-09 35.8 1.9 9.6e-05 22.1 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EGE06095.1 - 7.7e-09 35.4 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGE06095.1 - 5.7e-07 29.3 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGE06095.1 - 0.00011 22.4 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EGE06095.1 - 0.00044 19.9 0.0 0.00094 18.8 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EGE06095.1 - 0.0015 17.8 0.1 0.1 11.8 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EGE06095.1 - 0.017 15.8 0.1 7.3 7.3 0.1 3.2 3 0 0 3 3 3 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 EGE06095.1 - 0.029 14.0 0.0 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain DUF2118 PF09891.9 EGE06095.1 - 0.037 14.0 0.1 0.088 12.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) TMEM52 PF14979.6 EGE06096.1 - 0.25 11.2 0.8 0.35 10.8 0.8 1.2 1 0 0 1 1 1 0 Transmembrane 52 DUF4764 PF15961.5 EGE06096.1 - 0.32 9.6 3.9 0.37 9.4 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Ribosomal_L5_C PF00673.21 EGE06097.1 - 3.3e-22 78.5 0.0 4.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGE06097.1 - 2e-20 72.9 0.0 7.4e-20 71.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 EGE06098.1 - 6.9e-19 67.3 0.0 9e-19 66.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 EGE06099.1 - 2.6e-35 120.9 0.1 3.2e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Aa_trans PF01490.18 EGE06100.1 - 3.7e-37 128.0 16.3 3.4e-27 95.2 3.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TM_PBP2_N PF16296.5 EGE06100.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters SCAMP PF04144.13 EGE06100.1 - 7 6.9 8.8 5.4 7.3 1.6 2.2 2 0 0 2 2 2 0 SCAMP family AA_permease PF00324.21 EGE06101.1 - 8.1e-54 183.0 32.7 1e-53 182.7 32.7 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EGE06101.1 - 1.8e-22 79.9 0.0 8.2e-07 28.4 0.0 3.3 3 0 0 3 3 3 3 Solute carrier family 12 GHMP_kinases_N PF00288.26 EGE06102.1 - 3.3e-16 59.3 0.5 2.9e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGE06102.1 - 1.8e-09 37.8 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EGE06102.1 - 0.0004 19.9 0.0 0.0008 18.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 EGE06103.1 - 2.9e-18 65.0 0.3 0.00022 20.9 0.0 3.7 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat TPR_14 PF13428.6 EGE06103.1 - 0.44 11.5 3.2 0.56 11.2 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PALP PF00291.25 EGE06104.1 - 4.5e-56 190.4 0.3 2.6e-53 181.3 0.1 2.7 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme tRNA-synt_1g PF09334.11 EGE06106.1 - 4.8e-96 321.9 0.1 4.1e-95 318.8 0.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGE06106.1 - 2.1e-22 79.1 0.3 1.5e-11 43.3 0.0 3.5 2 2 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGE06106.1 - 3e-08 33.4 0.0 0.0022 17.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain NTF2 PF02136.20 EGE06107.1 - 2.9e-08 34.3 0.3 1.6e-06 28.6 0.3 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGE06107.1 - 0.0026 17.7 0.1 0.0038 17.2 0.1 1.4 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Ish1 PF10281.9 EGE06108.1 - 6.6e-07 29.5 0.1 1e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein ABATE PF07336.11 EGE06108.1 - 0.032 14.9 0.9 0.044 14.5 0.9 1.3 1 1 0 1 1 1 0 Putative stress-induced transcription regulator SAP PF02037.27 EGE06108.1 - 0.076 12.8 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 SAP domain SAM_2 PF07647.17 EGE06108.1 - 0.14 12.3 0.1 0.22 11.7 0.1 1.3 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) Ribosomal_L38e PF01781.18 EGE06109.1 - 1.1e-31 108.7 1.9 1.3e-31 108.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Acetyltransf_3 PF13302.7 EGE06110.1 - 8e-26 91.4 0.0 2.9e-25 89.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE06110.1 - 0.00062 19.7 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_4 PF13420.7 EGE06110.1 - 0.0014 18.8 0.3 0.0055 16.9 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGE06110.1 - 0.032 13.9 4.1 0.66 9.7 0.7 3.2 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain DNA_pol_D_N PF18018.1 EGE06111.1 - 5.6e-37 126.7 0.0 8.7e-37 126.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EGE06111.1 - 1.9e-35 122.2 0.0 5.3e-35 120.7 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B NMO PF03060.15 EGE06112.1 - 9.8e-53 179.7 0.5 1.3e-52 179.3 0.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGE06112.1 - 1.6e-06 27.4 1.2 2.1e-05 23.7 0.4 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGE06112.1 - 0.0027 16.8 3.5 0.0043 16.1 3.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 EGE06112.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Taxilin PF09728.9 EGE06113.1 - 4.3e-93 311.9 51.4 4.3e-93 311.9 51.4 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein GOLGA2L5 PF15070.6 EGE06113.1 - 0.64 8.6 43.3 0.087 11.5 33.0 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF3675 PF12428.8 EGE06113.1 - 0.83 10.2 3.3 9.2 6.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) TPR_MLP1_2 PF07926.12 EGE06113.1 - 1.1 9.3 51.3 0.35 11.0 14.5 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EGE06113.1 - 1.3 9.2 52.1 0.6 10.3 12.4 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding COG2 PF06148.11 EGE06113.1 - 2 8.5 26.4 1.1 9.4 0.4 3.8 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 UPF0242 PF06785.11 EGE06113.1 - 2.6 8.1 56.1 0.82 9.7 8.7 4.5 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 EGE06113.1 - 3.8 7.2 24.8 2 8.1 5.5 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 EGE06113.1 - 3.9 6.7 44.6 0.11 11.8 7.0 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Laminin_II PF06009.12 EGE06113.1 - 4.2 7.4 35.7 0.62 10.1 3.8 4.2 1 1 2 4 4 4 0 Laminin Domain II ERM PF00769.19 EGE06113.1 - 5.4 6.8 60.8 0.27 11.0 20.0 3.2 1 1 2 3 3 3 0 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 EGE06113.1 - 6 7.1 34.3 0.21 11.9 8.8 3.1 2 1 1 3 3 3 0 Zinc finger-containing protein DUF3584 PF12128.8 EGE06113.1 - 7.5 3.9 49.7 24 2.3 11.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) M16C_assoc PF08367.11 EGE06115.1 - 4.8e-74 248.7 0.3 8e-74 247.9 0.3 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGE06115.1 - 7.4e-24 84.8 0.0 7.1e-15 55.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGE06115.1 - 2.8e-10 40.3 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Methyltransf_25 PF13649.6 EGE06116.1 - 2.6e-17 63.3 0.1 6.6e-17 62.0 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06116.1 - 2.9e-16 59.9 0.1 5.1e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06116.1 - 3.1e-15 56.3 0.0 4.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06116.1 - 8.5e-13 48.9 0.0 1.5e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE06116.1 - 3.1e-12 46.7 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE06116.1 - 3.8e-07 29.7 0.0 6.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGE06116.1 - 3.7e-06 26.6 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EGE06116.1 - 4.5e-06 26.6 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 EGE06116.1 - 0.0001 21.4 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGE06116.1 - 0.00019 20.8 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EGE06116.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EGE06116.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EGE06116.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 EGE06116.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EGE06116.1 - 0.03 14.3 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGE06116.1 - 0.034 14.2 0.1 0.34 11.0 0.1 2.1 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_5 PF01795.19 EGE06116.1 - 0.061 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family DREV PF05219.12 EGE06116.1 - 0.066 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DRE2_N PF16803.5 EGE06116.1 - 0.19 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus DUF202 PF02656.15 EGE06117.1 - 5e-18 65.3 1.4 5e-18 65.3 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fumarate_red_C PF02300.17 EGE06117.1 - 0.021 14.9 1.0 0.036 14.2 1.0 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit C Cation_efflux PF01545.21 EGE06118.1 - 1e-54 185.3 4.1 1.8e-54 184.5 4.1 1.4 1 1 0 1 1 1 1 Cation efflux family TRAM_LAG1_CLN8 PF03798.16 EGE06119.1 - 5.3e-35 120.9 5.2 5.3e-35 120.9 5.2 1.5 2 0 0 2 2 2 1 TLC domain DUF2759 PF10958.8 EGE06119.1 - 0.054 13.2 0.4 5.9 6.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DIL PF01843.19 EGE06121.1 - 0.2 11.9 0.6 12 6.3 0.1 2.9 2 0 0 2 2 2 0 DIL domain HEPN_Swt1 PF18731.1 EGE06121.1 - 0.23 11.8 0.0 0.23 11.8 0.0 5.3 5 1 1 6 6 6 0 Swt1-like HEPN UBA_2 PF08587.11 EGE06121.1 - 0.39 10.9 19.4 47 4.2 0.0 9.3 7 2 3 10 10 10 0 Ubiquitin associated domain (UBA) Ribosomal_L27e PF01777.18 EGE06122.1 - 1.6e-37 127.7 3.8 2.1e-37 127.3 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGE06122.1 - 0.0013 18.6 0.1 0.0045 16.9 0.1 1.9 1 0 0 1 1 1 1 KOW motif Band_7 PF01145.25 EGE06124.1 - 4.7e-27 95.1 2.7 7.4e-27 94.5 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF3598 PF12204.8 EGE06124.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) Band_7_1 PF13421.6 EGE06124.1 - 0.027 14.2 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family PHD PF00628.29 EGE06125.1 - 1.9e-07 30.8 9.3 3.6e-07 30.0 9.3 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EGE06125.1 - 0.61 10.1 7.8 1.2 9.1 7.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 CoA_transf_3 PF02515.17 EGE06126.1 - 7.7e-129 430.0 0.0 8.9e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 EGE06127.1 - 6.6e-45 151.0 0.6 1.7e-22 79.2 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain Lumazine_bd_2 PF12893.7 EGE06127.1 - 0.0068 17.1 0.1 0.02 15.5 0.0 1.8 1 1 0 1 1 1 1 Putative lumazine-binding YabP PF07873.11 EGE06127.1 - 0.028 14.2 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 YabP family Brix PF04427.18 EGE06128.1 - 7.9e-49 166.4 0.2 1.1e-48 165.9 0.2 1.2 1 0 0 1 1 1 1 Brix domain PPP4R2 PF09184.11 EGE06128.1 - 1.2 8.7 12.4 2.4 7.7 12.4 1.5 1 0 0 1 1 1 0 PPP4R2 DEAD PF00270.29 EGE06129.1 - 1.6e-47 161.5 0.0 2.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE06129.1 - 1.2e-30 106.1 0.0 1.2e-29 102.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE06129.1 - 2.3e-05 24.5 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PGM_PMM_I PF02878.16 EGE06130.1 - 2.1e-18 66.4 0.7 5.2e-08 32.7 0.0 3.2 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EGE06130.1 - 2.1e-10 40.6 0.8 6.9e-10 39.0 0.2 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EGE06130.1 - 0.00048 20.3 0.5 0.0024 18.1 0.5 2.1 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGE06130.1 - 0.0017 18.9 0.6 0.012 16.2 0.3 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Per1 PF04080.13 EGE06131.1 - 8.3e-104 346.9 13.6 1e-103 346.5 13.6 1.1 1 0 0 1 1 1 1 Per1-like family NiFe_hyd_3_EhaA PF17367.2 EGE06131.1 - 0.22 11.7 1.7 11 6.2 0.1 2.5 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF2007 PF09413.10 EGE06132.1 - 0.0061 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative prokaryotic signal transducing protein Methyltransf_25 PF13649.6 EGE06133.1 - 9.9e-12 45.4 0.0 2.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGE06133.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGE06133.1 - 2.1e-10 40.6 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06133.1 - 1.3e-07 32.1 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE06133.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGE06133.1 - 4.9e-06 25.7 0.0 6.8e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGE06133.1 - 2e-05 24.0 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EGE06133.1 - 3.6e-05 23.7 0.4 0.00011 22.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGE06133.1 - 0.00029 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGE06133.1 - 0.0004 21.1 0.0 0.00084 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGE06133.1 - 0.0077 16.4 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGE06133.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 EGE06133.1 - 0.019 14.8 0.1 0.044 13.6 0.1 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 EGE06133.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGE06133.1 - 0.033 13.9 0.2 0.056 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EGE06133.1 - 0.036 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EGE06133.1 - 0.045 13.5 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase MaoC_dehydratas PF01575.19 EGE06134.1 - 7.8e-24 83.6 0.0 4.6e-23 81.1 0.0 2.0 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGE06134.1 - 6.2e-10 39.3 0.0 0.00012 22.3 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.16 EGE06135.1 - 1.2e-36 126.9 0.0 1.7e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGE06135.1 - 1.5e-12 48.0 0.0 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGE06135.1 - 0.0021 17.2 0.0 0.015 14.4 0.0 1.9 1 1 0 1 1 1 1 CsiD Exc PF07825.11 EGE06135.1 - 0.55 10.3 2.2 38 4.4 0.2 3.0 3 0 0 3 3 3 0 Excisionase-like protein AAA PF00004.29 EGE06136.1 - 1.4e-40 138.8 0.0 3.5e-40 137.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGE06136.1 - 9.8e-19 67.1 0.2 2e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGE06136.1 - 4.8e-09 35.9 0.0 1.3e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGE06136.1 - 8.5e-05 23.0 1.9 0.014 15.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGE06136.1 - 0.00019 21.4 1.6 0.00072 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGE06136.1 - 0.0003 20.6 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGE06136.1 - 0.0025 18.0 2.5 0.006 16.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 EGE06136.1 - 0.0027 17.2 1.1 0.073 12.5 0.1 2.7 3 0 0 3 3 3 1 PhoH-like protein DUF815 PF05673.13 EGE06136.1 - 0.0029 16.8 1.3 0.051 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGE06136.1 - 0.0053 17.0 4.6 0.084 13.1 0.0 3.2 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EGE06136.1 - 0.008 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGE06136.1 - 0.011 15.8 0.0 0.036 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGE06136.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EGE06136.1 - 0.098 12.2 0.3 0.49 9.9 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EGE06136.1 - 0.51 9.4 2.2 5.6 6.0 0.1 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGE06136.1 - 0.53 10.0 0.0 0.53 10.0 0.0 3.1 2 1 0 3 3 2 0 AAA domain CLZ PF16526.5 EGE06136.1 - 1.1 9.7 12.5 0.2 12.1 7.3 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RPN2_C PF18004.1 EGE06136.1 - 8 6.4 10.4 17 5.3 10.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GH-E PF14410.6 EGE06137.1 - 0.0082 16.5 0.4 0.019 15.4 0.4 1.6 1 0 0 1 1 1 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues LRR_8 PF13855.6 EGE06137.1 - 0.11 12.3 0.2 0.37 10.6 0.2 1.9 1 0 0 1 1 1 0 Leucine rich repeat Pkinase PF00069.25 EGE06138.1 - 3.6e-68 229.8 0.0 5.4e-68 229.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06138.1 - 1.6e-31 109.6 0.0 2.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGE06138.1 - 6.7e-13 49.1 1.5 1.9e-12 47.7 0.1 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGE06138.1 - 1.1e-09 38.1 0.0 4.8e-09 36.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 EGE06138.1 - 1.9e-08 34.5 0.0 6.3e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 EGE06138.1 - 0.0019 17.2 0.2 0.0019 17.2 0.2 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGE06138.1 - 0.0071 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGE06138.1 - 0.056 13.1 0.4 2.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LPD39 PF18858.1 EGE06139.1 - 0.073 13.2 1.3 0.11 12.6 1.3 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 AP3D1 PF06375.11 EGE06140.1 - 0.36 11.1 7.3 0.42 10.8 7.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Neur_chan_memb PF02932.16 EGE06140.1 - 0.44 10.6 2.0 0.47 10.5 2.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Jak1_Phl PF17887.1 EGE06140.1 - 0.96 9.4 4.6 1.3 9.0 4.6 1.2 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Dishevelled PF02377.15 EGE06141.1 - 0.005 17.3 2.2 0.007 16.8 2.2 1.2 1 0 0 1 1 1 1 Dishevelled specific domain Glypican PF01153.19 EGE06141.1 - 0.59 8.9 4.0 0.71 8.6 4.0 1.0 1 0 0 1 1 1 0 Glypican Nop14 PF04147.12 EGE06141.1 - 3.7 5.6 8.8 4.1 5.5 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGE06141.1 - 7.4 5.8 7.7 9.8 5.4 7.7 1.1 1 0 0 1 1 1 0 NOA36 protein Cytomega_UL84 PF06284.11 EGE06141.1 - 8.7 4.7 7.7 12 4.2 7.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Cyclin PF08613.11 EGE06142.1 - 2.7e-11 44.1 0.0 6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin TFIIA PF03153.13 EGE06142.1 - 0.0013 18.9 10.7 0.0013 18.9 10.7 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 EGE06142.1 - 0.0025 16.5 0.5 0.0042 15.7 0.5 1.2 1 0 0 1 1 1 1 Fusaric acid resistance protein family MMR1 PF08505.10 EGE06142.1 - 0.021 15.1 2.4 0.037 14.3 2.4 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 EGE06142.1 - 0.039 12.7 0.7 0.05 12.4 0.7 1.2 1 0 0 1 1 1 0 Presenilin PAXIP1_C PF15364.6 EGE06142.1 - 0.064 13.6 3.3 0.14 12.4 3.3 1.5 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cyclin_N PF00134.23 EGE06142.1 - 0.079 12.7 1.5 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain Neur_chan_memb PF02932.16 EGE06142.1 - 0.72 9.9 2.7 1.1 9.2 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 EGE06142.1 - 0.8 9.4 4.1 1.4 8.6 4.1 1.3 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 EGE06142.1 - 2.3 8.3 5.2 4.1 7.5 5.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 EGE06142.1 - 2.9 7.1 6.4 0.91 8.8 3.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Suf PF05843.14 EGE06142.1 - 5.3 6.9 10.0 0.46 10.4 4.6 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Abhydrolase_1 PF00561.20 EGE06144.1 - 2.1e-06 27.6 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE06144.1 - 5.4e-06 27.2 0.0 8.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE06144.1 - 8.6e-05 21.9 0.0 0.00018 20.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGE06144.1 - 0.035 13.6 0.1 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Zn_clus PF00172.18 EGE06145.1 - 4.2e-07 30.0 6.7 4.2e-07 30.0 6.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE06145.1 - 3.9e-05 22.6 3.5 3.9e-05 22.6 3.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain 3-PAP PF12578.8 EGE06145.1 - 0.12 12.1 0.4 0.28 10.9 0.4 1.6 1 0 0 1 1 1 0 Myotubularin-associated protein PocR PF10114.9 EGE06145.1 - 1 9.2 2.8 2 8.2 2.8 1.5 1 0 0 1 1 1 0 Sensory domain found in PocR His_Phos_1 PF00300.22 EGE06146.1 - 8.7e-30 103.9 0.0 1.8e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EGE06146.1 - 0.0033 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YL1 PF05764.13 EGE06146.1 - 4.1 7.5 10.7 0.51 10.4 3.3 2.6 3 0 0 3 3 3 0 YL1 nuclear protein Dor1 PF04124.12 EGE06147.1 - 1.5e-52 178.4 0.6 7.3e-43 146.5 0.6 2.5 1 1 1 2 2 2 2 Dor1-like family Sec8_exocyst PF04048.14 EGE06147.1 - 0.023 14.6 0.6 0.063 13.2 0.6 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vps51 PF08700.11 EGE06147.1 - 0.059 13.5 2.2 0.083 13.0 0.4 2.2 2 0 0 2 2 2 0 Vps51/Vps67 Snf7 PF03357.21 EGE06147.1 - 6.7 6.3 6.6 0.29 10.7 0.7 1.8 2 0 0 2 2 2 0 Snf7 COG5 PF10392.9 EGE06147.1 - 6.9 6.9 9.9 9.8 6.4 3.7 3.5 3 1 0 3 3 3 0 Golgi transport complex subunit 5 EAF PF09816.9 EGE06148.1 - 2.2e-16 60.1 0.1 2.2e-16 60.1 0.1 2.3 3 0 0 3 3 3 1 RNA polymerase II transcription elongation factor Pep_M12B_propep PF01562.19 EGE06148.1 - 0.33 11.2 4.7 15 5.8 0.0 2.5 2 0 0 2 2 2 0 Reprolysin family propeptide Cyclin_N PF00134.23 EGE06149.1 - 3.6e-14 52.6 0.1 6.8e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGE06149.1 - 0.0028 17.7 0.1 0.046 13.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 EGE06149.1 - 0.0051 16.8 2.4 0.068 13.2 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Prothymosin PF03247.14 EGE06149.1 - 5.6 7.5 18.5 0.93 10.0 9.4 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.10 EGE06150.1 - 0.34 11.3 9.7 0.28 11.6 7.5 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Use1 PF09753.9 EGE06150.1 - 0.83 9.3 7.9 1.6 8.4 7.9 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Peptidase_S64 PF08192.11 EGE06150.1 - 9.1 4.6 15.1 6.3 5.2 0.6 2.1 2 0 0 2 2 2 0 Peptidase family S64 Methyltransf_23 PF13489.6 EGE06151.1 - 8.5e-29 100.5 0.0 1.2e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE06151.1 - 0.00016 22.3 0.0 0.00055 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06151.1 - 0.0095 16.7 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06151.1 - 0.037 14.7 0.0 0.086 13.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 EGE06152.1 - 2.1e-48 165.7 0.4 2.5e-48 165.4 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE06152.1 - 9.4e-09 34.9 0.0 0.0052 16.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGE06152.1 - 2.3e-06 26.7 0.3 0.023 13.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EGE06152.1 - 3.7e-06 27.0 0.2 0.023 14.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EGE06152.1 - 5.4e-06 25.7 0.1 6.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGE06152.1 - 6.7e-05 23.0 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGE06152.1 - 0.00069 18.8 0.8 0.46 9.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 EGE06152.1 - 0.0027 17.0 0.1 1.4 8.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EGE06152.1 - 0.011 16.3 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGE06152.1 - 0.019 14.1 0.1 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EGE06152.1 - 0.025 14.0 0.0 0.91 8.8 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EGE06152.1 - 0.23 10.6 0.1 3.7 6.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Herpes_pp85 PF04637.12 EGE06152.1 - 0.63 8.4 2.4 0.9 7.9 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 EGE06152.1 - 3.7 7.1 5.8 10 5.7 5.8 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ETF_QO PF05187.13 EGE06153.1 - 6.9e-42 141.8 0.9 1.4e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EGE06153.1 - 5.2e-09 36.2 0.0 7.4e-05 22.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE06153.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGE06153.1 - 0.00011 21.1 0.2 0.00018 20.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EGE06153.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE06153.1 - 0.00012 21.3 0.3 0.0084 15.2 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EGE06153.1 - 0.00023 21.6 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE06153.1 - 0.00046 19.5 0.0 0.0013 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE06153.1 - 0.00081 18.7 0.0 0.0035 16.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EGE06153.1 - 0.00087 18.3 0.0 0.035 13.0 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.19 EGE06153.1 - 0.00092 18.5 0.4 0.0021 17.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGE06153.1 - 0.012 14.9 0.3 0.018 14.3 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE06153.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 EGE06153.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.22 EGE06154.1 - 2.9e-23 81.4 0.1 1.1e-12 47.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE06154.1 - 0.00095 19.0 0.0 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 EGE06154.1 - 0.059 13.4 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_3 PF08777.11 EGE06154.1 - 0.2 11.7 0.0 1.3 9.2 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif CSD PF00313.22 EGE06154.1 - 0.22 11.4 0.6 1.4 8.8 0.1 2.1 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain FolB PF02152.18 EGE06155.1 - 7.9e-28 97.2 0.6 1.9e-22 79.9 0.5 2.5 3 0 0 3 3 3 2 Dihydroneopterin aldolase Pkinase PF00069.25 EGE06156.1 - 6.2e-66 222.5 0.0 8.4e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06156.1 - 2.4e-30 105.7 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE06156.1 - 0.048 12.6 0.2 0.076 11.9 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGE06156.1 - 0.073 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGE06156.1 - 0.14 12.1 1.1 3.1 7.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ndc80_HEC PF03801.13 EGE06158.1 - 2.1e-60 202.8 0.5 4e-60 201.9 0.5 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Spc7 PF08317.11 EGE06158.1 - 0.013 14.4 39.9 0.21 10.4 18.8 2.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF812 PF05667.11 EGE06158.1 - 0.058 12.3 32.6 0.014 14.4 14.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ProRS-C_2 PF09181.10 EGE06158.1 - 0.39 10.9 3.8 11 6.3 0.5 3.0 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal TPR_MLP1_2 PF07926.12 EGE06158.1 - 2.9 7.9 45.4 1 9.4 3.7 4.1 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Cep57_CLD PF14073.6 EGE06158.1 - 4.1 7.4 43.5 0.14 12.1 18.5 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 Golgin_A5 PF09787.9 EGE06158.1 - 5.7 6.3 46.0 1.2 8.6 14.7 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 CEP63 PF17045.5 EGE06158.1 - 7.2 6.4 40.0 0.96 9.3 12.0 3.3 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Adenylsucc_synt PF00709.21 EGE06158.1 - 8.6 5.2 8.8 7.5 5.4 4.1 2.4 2 0 0 2 2 2 0 Adenylosuccinate synthetase Pex14_N PF04695.13 EGE06159.1 - 1.8e-40 139.2 0.0 1.8e-40 139.2 0.0 3.3 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Golgin_A5 PF09787.9 EGE06159.1 - 0.0027 17.2 1.2 0.0046 16.5 1.2 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF1043 PF06295.12 EGE06159.1 - 0.032 14.2 0.3 0.09 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) SYCE1 PF15233.6 EGE06159.1 - 0.092 12.8 4.2 0.17 12.0 4.2 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 LMBR1 PF04791.16 EGE06159.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.12 EGE06159.1 - 0.38 10.8 1.9 1.3 9.1 1.6 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 EGE06159.1 - 0.78 10.0 6.4 0.12 12.7 2.0 1.9 2 1 0 2 2 2 0 Zinc finger-containing protein DUF1664 PF07889.12 EGE06159.1 - 1.1 9.3 2.6 6.5 6.8 1.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 EGE06159.1 - 4.3 4.7 14.0 0.014 13.0 4.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 EGE06161.1 - 6.2e-34 117.5 0.0 1.1e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGE06161.1 - 8.5e-06 25.4 0.3 0.00086 18.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 EGE06161.1 - 0.00037 20.2 0.0 0.00054 19.7 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_23 PF13476.6 EGE06161.1 - 0.0028 18.2 0.2 0.0077 16.8 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGE06161.1 - 0.0062 16.3 0.2 0.02 14.7 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.7 EGE06161.1 - 0.027 13.4 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.6 EGE06161.1 - 0.037 14.2 0.4 0.2 11.9 0.1 2.4 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EGE06161.1 - 0.038 14.3 0.3 0.15 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE06161.1 - 0.039 13.9 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EGE06161.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EGE06161.1 - 0.12 12.2 0.3 0.51 10.1 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TTL PF03133.15 EGE06164.1 - 2.1e-55 187.9 0.0 2.9e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EGE06164.1 - 1e-48 165.7 0.0 1.5e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EGE06164.1 - 0.0027 17.0 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Seipin PF06775.14 EGE06165.1 - 1.1e-58 198.6 0.1 1.4e-58 198.3 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.15 EGE06166.1 - 7.7e-141 469.3 3.6 8.9e-141 469.1 0.3 2.6 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGE06166.1 - 3.5e-93 311.1 3.5 1.2e-92 309.4 3.5 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EGE06166.1 - 4.3e-51 172.7 2.0 1e-50 171.5 2.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EGE06166.1 - 1.5e-40 138.4 0.0 6.6e-40 136.3 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGE06166.1 - 5.2e-29 101.3 2.5 1.3e-28 100.0 0.0 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FCH PF00611.23 EGE06167.1 - 4.6e-15 55.7 0.0 3.6e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Rapsyn_N PF10579.9 EGE06167.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region DASH_Duo1 PF08651.10 EGE06168.1 - 6.2e-32 109.2 0.1 1.5e-31 108.0 0.1 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 Retinal PF15449.6 EGE06168.1 - 0.0084 14.0 11.0 0.011 13.6 11.0 1.0 1 0 0 1 1 1 1 Retinal protein PEARLI-4 PF05278.12 EGE06168.1 - 0.036 13.6 4.5 0.071 12.7 4.5 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF745 PF05335.13 EGE06168.1 - 0.071 12.8 7.5 0.12 12.1 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) 3HCDH_N PF02737.18 EGE06168.1 - 0.37 10.6 4.6 0.64 9.9 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain U79_P34 PF03064.16 EGE06168.1 - 3.7 6.8 11.4 5.9 6.2 10.4 1.9 2 1 0 2 2 2 0 HSV U79 / HCMV P34 RNase_H2-Ydr279 PF09468.10 EGE06171.1 - 3.3e-38 131.4 4.1 3.4e-38 131.3 0.4 2.4 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EGE06171.1 - 8.1e-22 77.3 0.1 2.2e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain U1snRNP70_N PF12220.8 EGE06171.1 - 0.019 15.6 1.0 0.019 15.6 1.0 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Selenoprotein_S PF06936.11 EGE06171.1 - 4 7.2 9.3 0.22 11.3 3.9 1.6 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF1980 PF09323.10 EGE06171.1 - 9.3 6.1 5.8 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) GalKase_gal_bdg PF10509.9 EGE06172.1 - 1.1e-18 66.6 0.0 2.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGE06172.1 - 1.1e-15 57.8 0.0 2.4e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGE06172.1 - 3.3e-14 52.8 1.6 6.5e-14 51.9 1.6 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain TPP_enzyme_N PF02776.18 EGE06173.1 - 9.4e-56 188.1 0.1 1.5e-54 184.2 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGE06173.1 - 8.3e-49 165.3 0.3 1.8e-46 157.7 0.0 3.0 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGE06173.1 - 4e-40 136.7 0.2 1e-39 135.4 0.2 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EGE06173.1 - 0.046 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FANCL_C PF11793.8 EGE06174.1 - 4.2e-06 26.9 2.4 9.3e-06 25.7 2.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EGE06174.1 - 7.2e-06 26.0 5.6 1.6e-05 24.9 5.6 1.7 1 0 0 1 1 1 1 RING-variant domain zf-TFIIB PF13453.6 EGE06174.1 - 0.0066 15.8 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 Transcription factor zinc-finger PhnA_Zn_Ribbon PF08274.12 EGE06174.1 - 0.0089 16.0 0.3 0.022 14.7 0.3 1.7 1 0 0 1 1 1 1 PhnA Zinc-Ribbon zf-RING_2 PF13639.6 EGE06174.1 - 0.014 15.7 4.5 0.044 14.1 4.5 1.9 1 0 0 1 1 1 0 Ring finger domain MRP-L28 PF09812.9 EGE06175.1 - 1.5e-05 25.2 0.1 1.9e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 EGE06176.1 - 2.9e-47 160.3 0.0 3.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE06176.1 - 1.6e-20 73.5 0.0 2.4e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE06176.1 - 2.8e-06 26.9 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGE06176.1 - 0.0039 16.6 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGE06176.1 - 0.058 13.5 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGE06176.1 - 0.063 13.0 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EGE06176.1 - 0.076 12.4 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ADH_zinc_N PF00107.26 EGE06176.1 - 0.12 12.4 0.0 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AAA_21 PF13304.6 EGE06176.1 - 0.26 11.1 0.1 0.6 9.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NST1 PF13945.6 EGE06177.1 - 6.2e-80 267.8 4.6 6.2e-80 267.8 4.6 4.9 3 2 2 5 5 5 1 Salt tolerance down-regulator Vps35 PF03635.17 EGE06178.1 - 0 1022.4 0.2 0 1022.2 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 CobT PF06213.12 EGE06178.1 - 2 7.7 9.6 3.9 6.8 9.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ge1_WD40 PF16529.5 EGE06180.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1749 PF08538.10 EGE06181.1 - 2.8e-89 299.1 0.0 3.2e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EGE06181.1 - 0.00018 20.8 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EGE06181.1 - 0.0037 17.1 0.0 0.06 13.2 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_3 PF07859.13 EGE06181.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF900 PF05990.12 EGE06181.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glycos_transf_2 PF00535.26 EGE06182.1 - 7.9e-35 120.2 0.0 9.9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGE06182.1 - 2.2e-14 53.9 0.0 2.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGE06182.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGE06182.1 - 0.0019 17.7 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 UPA_2 PF17809.1 EGE06182.1 - 0.065 13.1 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 UPA domain TPR_19 PF14559.6 EGE06183.1 - 1.5e-05 25.4 0.0 0.35 11.4 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE06183.1 - 0.0018 19.0 0.5 70 4.6 0.0 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE06183.1 - 0.0018 18.8 0.1 6.5 7.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF4332 PF14229.6 EGE06183.1 - 0.0039 17.4 0.1 0.0089 16.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) PknG_TPR PF16918.5 EGE06183.1 - 0.007 15.1 0.0 0.017 13.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 EGE06183.1 - 0.014 15.6 0.0 0.38 11.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE06183.1 - 0.025 15.2 0.2 39 5.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HlyIII PF03006.20 EGE06185.1 - 1.1e-60 205.1 13.2 1.4e-60 204.8 13.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SUIM_assoc PF16619.5 EGE06185.1 - 0.46 10.6 9.7 0.77 9.9 9.7 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DivIC PF04977.15 EGE06185.1 - 1.3 8.9 7.4 2.3 8.1 7.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2722 PF10846.8 EGE06185.1 - 1.7 7.5 6.6 2.2 7.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RskA PF10099.9 EGE06185.1 - 3.6 7.9 10.3 0.19 12.0 4.2 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA 60KD_IMP PF02096.20 EGE06185.1 - 4.5 7.2 5.4 0.93 9.4 0.1 2.3 2 1 0 2 2 2 0 60Kd inner membrane protein Spt20 PF12090.8 EGE06185.1 - 8.2 6.0 10.6 12 5.5 10.6 1.2 1 0 0 1 1 1 0 Spt20 family adh_short_C2 PF13561.6 EGE06186.1 - 4.3e-48 163.9 4.8 5.3e-40 137.4 3.6 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE06186.1 - 1.4e-45 155.1 3.3 1.8e-45 154.8 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE06186.1 - 5.4e-15 55.8 0.7 7.5e-15 55.3 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGE06186.1 - 0.0042 17.0 0.5 0.0061 16.5 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EGE06186.1 - 0.035 14.2 0.5 0.097 12.7 0.5 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DDE_Tnp_1 PF01609.21 EGE06186.1 - 0.046 13.4 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain GDP_Man_Dehyd PF16363.5 EGE06186.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGE06186.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGE06186.1 - 0.13 11.4 0.6 0.36 9.9 0.6 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 EGE06186.1 - 0.16 12.0 2.7 0.65 10.0 1.4 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EGE06187.1 - 4.3e-51 173.8 0.0 5.1e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06187.1 - 7.5e-31 107.3 0.0 9e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE06187.1 - 0.00077 19.5 0.0 0.0055 16.7 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE06187.1 - 0.00078 18.8 0.0 0.0039 16.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGE06187.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGE06187.1 - 0.18 10.7 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EGE06187.1 - 0.21 11.1 0.0 0.39 10.3 0.0 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase Spore_III_AF PF09581.10 EGE06189.1 - 0.12 12.4 4.4 0.13 12.3 4.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4746 PF15928.5 EGE06189.1 - 0.76 9.1 8.1 0.83 9.0 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EGE06189.1 - 8.8 5.0 7.8 9.1 4.9 7.8 1.0 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EGE06192.1 - 2.5e-53 181.2 0.0 3.9e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06192.1 - 1.7e-23 83.2 0.0 1e-22 80.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EGE06192.1 - 0.014 14.4 0.2 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EGE06192.1 - 0.024 13.9 0.0 6 6.1 0.0 2.4 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EGE06192.1 - 2.6 6.7 8.6 10 4.8 8.6 2.1 1 1 0 1 1 1 0 Fungal protein kinase TMA7 PF09072.10 EGE06193.1 - 5.6e-25 88.0 23.6 6.2e-25 87.8 23.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Filament PF00038.21 EGE06194.1 - 0.03 13.9 0.2 0.045 13.3 0.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein Fib_alpha PF08702.10 EGE06194.1 - 0.06 13.5 2.7 0.17 12.1 2.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 EGE06194.1 - 0.11 12.6 1.0 0.2 11.7 1.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.6 EGE06194.1 - 0.32 11.2 1.5 12 6.1 1.2 2.3 1 1 1 2 2 2 0 Up-regulated During Septation Cyt-b5 PF00173.28 EGE06195.1 - 3.6e-15 55.9 0.0 4.7e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.9 EGE06196.1 - 1.1e-59 198.4 12.8 5.1e-11 42.7 0.0 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EGE06196.1 - 8.6e-06 25.4 0.2 0.27 11.0 0.0 3.5 3 0 0 3 3 3 2 HeH/LEM domain Recombinase PF07508.13 EGE06196.1 - 0.051 14.0 0.4 0.6 10.5 0.1 2.9 2 1 0 2 2 2 0 Recombinase OAR PF03826.17 EGE06196.1 - 0.054 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 OAR domain YtxH PF12732.7 EGE06196.1 - 0.082 13.5 2.5 3.2 8.4 0.2 3.4 3 0 0 3 3 3 0 YtxH-like protein SAP PF02037.27 EGE06196.1 - 0.13 12.0 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 0 SAP domain PQ-loop PF04193.14 EGE06197.1 - 5.3e-10 38.9 15.5 5.4e-09 35.7 5.3 3.6 4 0 0 4 4 4 2 PQ loop repeat TrbC PF04956.13 EGE06197.1 - 0.079 13.2 5.0 0.098 12.9 2.9 2.2 1 1 0 1 1 1 0 TrbC/VIRB2 family OppC_N PF12911.7 EGE06197.1 - 0.15 12.1 4.7 0.25 11.4 0.1 3.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Nucleo_P87 PF07267.11 EGE06198.1 - 0.1 11.5 7.3 0.1 11.5 7.3 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2951 PF11166.8 EGE06199.1 - 0.026 14.7 0.0 0.057 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Gly-zipper_Omp PF13488.6 EGE06199.1 - 0.33 11.0 6.4 0.74 9.9 6.4 1.5 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 EGE06199.1 - 0.63 10.2 4.2 1.5 9.0 4.2 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ndc1_Nup PF09531.10 EGE06199.1 - 2.1 6.9 6.5 4.3 5.9 6.5 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIM3 PF17096.5 EGE06199.1 - 2.9 8.9 8.4 3.8 8.5 5.5 2.7 3 1 0 3 3 3 0 Altered inheritance of mitochondria protein 3 FAD_binding_4 PF01565.23 EGE06201.1 - 5.6e-23 81.2 2.8 8.8e-23 80.6 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE06201.1 - 1.6e-08 34.5 0.1 3.5e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Aim21 PF11489.8 EGE06202.1 - 4.9e-166 554.7 91.4 4.9e-166 554.7 91.4 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 EGE06203.1 - 1.3e-39 135.0 12.1 1.6e-39 134.7 12.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Trep_Strep PF09605.10 EGE06203.1 - 0.096 12.7 0.5 0.096 12.7 0.5 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CbiN PF02553.15 EGE06203.1 - 1 9.4 4.2 0.49 10.4 0.4 2.2 2 0 0 2 2 2 0 Cobalt transport protein component CbiN DUF2721 PF11026.8 EGE06203.1 - 2.1 8.3 11.6 0.51 10.2 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PRA1 PF03208.19 EGE06203.1 - 8.6 6.0 10.5 17 5.0 10.5 1.5 1 1 0 1 1 1 0 PRA1 family protein ABC2_membrane_2 PF12679.7 EGE06203.1 - 9.4 5.4 12.4 23 4.1 12.0 1.7 1 1 1 2 2 2 0 ABC-2 family transporter protein NTF2 PF02136.20 EGE06204.1 - 3.8e-33 114.6 0.1 4.4e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGE06204.1 - 0.053 13.5 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Surp PF01805.20 EGE06205.1 - 6.4e-09 35.7 0.0 1.2e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Surp module RXT2_N PF08595.11 EGE06205.1 - 1 9.4 7.1 0.15 12.1 0.5 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF1765 PF08578.10 EGE06206.1 - 5e-42 143.3 1.0 9.7e-42 142.4 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.9 EGE06208.1 - 1.3e-26 92.4 2.1 1.7e-26 91.9 2.1 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.19 EGE06209.1 - 1.9e-37 127.2 0.0 1.6e-19 69.7 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGE06209.1 - 1.3e-10 40.6 0.9 1.3e-10 40.6 0.9 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 EGE06209.1 - 0.00032 20.8 0.0 0.00055 20.0 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EGE06209.1 - 0.06 13.4 0.0 2.7 8.1 0.0 2.3 2 1 0 2 2 2 0 Cyclin, C-terminal domain DUF1610 PF07754.11 EGE06209.1 - 0.26 11.3 2.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TFR_dimer PF04253.15 EGE06210.1 - 1.3e-33 115.7 0.1 2.3e-33 114.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGE06210.1 - 3e-16 59.7 0.0 7.9e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EGE06210.1 - 1.2e-14 54.0 0.1 2.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 PA domain HMG_CoA_synt_C PF08540.10 EGE06211.1 - 5e-104 347.8 0.2 6.3e-104 347.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGE06211.1 - 4e-96 319.9 0.1 6.4e-96 319.2 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GFO_IDH_MocA PF01408.22 EGE06213.1 - 4.1e-06 27.6 0.0 7.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGE06213.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.16 EGE06214.1 - 1.4e-33 115.6 0.2 2e-33 115.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGE06214.1 - 9.1e-26 90.3 0.0 1.7e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGE06214.1 - 4.4e-17 62.6 0.0 1.1e-16 61.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGE06214.1 - 7.3e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 EGE06215.1 - 4.8e-27 95.5 0.0 5.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF2207 PF09972.9 EGE06216.1 - 0.25 10.1 2.9 0.52 9.0 2.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.24 EGE06218.1 - 2e-14 53.3 0.6 4.4e-14 52.2 0.6 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE06218.1 - 4.2e-06 25.9 3.9 6.6e-06 25.3 3.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TSP_1 PF00090.19 EGE06219.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.2 2 0 0 2 2 2 0 Thrombospondin type 1 domain Nucleoporin2 PF04096.14 EGE06220.1 - 0.14 12.2 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin autopeptidase DUF3357 PF11837.8 EGE06221.1 - 0.11 12.9 0.1 0.15 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF2116 PF09889.9 EGE06221.1 - 0.55 10.3 3.3 0.97 9.5 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Piwi PF02171.17 EGE06222.1 - 1e-36 126.7 2.8 8.2e-20 71.2 0.0 2.6 2 1 1 3 3 3 2 Piwi domain ArgoN PF16486.5 EGE06222.1 - 1.1e-21 77.8 0.1 4e-21 76.1 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGE06222.1 - 1.8e-14 53.2 2.7 1.1e-13 50.6 0.2 2.4 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EGE06222.1 - 1.8e-13 50.5 0.5 3.4e-13 49.6 0.5 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGE06222.1 - 6.6e-10 39.1 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EGE06222.1 - 3.1e-09 37.0 0.1 7.2e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PerB PF06590.11 EGE06222.1 - 0.076 13.5 0.1 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 PerB protein Y_phosphatase PF00102.27 EGE06223.1 - 8.9e-55 185.8 0.0 1.2e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGE06223.1 - 0.0011 19.1 0.0 0.0026 17.9 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGE06223.1 - 0.0096 15.7 0.2 0.03 14.1 0.2 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGE06223.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Ig_C19orf38 PF17737.1 EGE06223.1 - 0.073 13.4 0.1 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Ig domain in C19orf38 (HIDE1) CDC45 PF02724.14 EGE06223.1 - 1.5 7.0 5.1 1.8 6.8 5.1 1.3 1 0 0 1 1 1 0 CDC45-like protein VanZ PF04892.12 EGE06224.1 - 1.8e-07 31.8 1.1 2.5e-07 31.4 0.5 1.4 1 1 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 EGE06224.1 - 0.76 9.5 0.0 0.76 9.5 0.0 2.2 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Bromodomain PF00439.25 EGE06225.1 - 1.1e-17 63.9 0.2 2.6e-17 62.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EGE06225.1 - 1.7e-08 34.3 0.0 5.1e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated NADH_Oxid_Nqo15 PF11497.8 EGE06225.1 - 0.085 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF3947 PF13135.6 EGE06225.1 - 4.1 7.6 7.1 8.9 6.6 7.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) TPP_enzyme_N PF02776.18 EGE06226.1 - 9.6e-32 110.0 0.0 1.5e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGE06226.1 - 1.4e-20 73.5 0.0 2.9e-20 72.4 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGE06226.1 - 1.3e-14 54.2 0.0 3.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EGE06226.1 - 0.0053 15.8 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component CDC73_C PF05179.14 EGE06227.1 - 1.2e-58 197.3 0.0 1.8e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal X PF00739.19 EGE06227.1 - 0.27 11.4 0.1 0.27 11.4 0.1 2.4 3 1 0 3 3 3 0 Trans-activation protein X 4HBT PF03061.22 EGE06228.1 - 1.7e-13 50.7 0.0 2.5e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGE06228.1 - 6.5e-06 26.6 0.0 8.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.18 EGE06229.1 - 4.2e-27 94.8 0.1 4.2e-27 94.8 0.1 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CCDC53 PF10152.9 EGE06229.1 - 0.58 10.6 15.3 0.074 13.5 7.2 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex BORG_CEP PF14957.6 EGE06229.1 - 2.3 9.4 17.2 3.1 9.0 9.1 2.4 2 0 0 2 2 2 0 Cdc42 effector GREB1 PF15782.5 EGE06229.1 - 6 3.9 7.0 8.3 3.4 7.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MRP-L47 PF06984.13 EGE06230.1 - 9.8e-21 73.7 0.2 1.6e-20 73.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 EGE06231.1 - 6.1e-152 506.1 0.1 1.5e-130 435.7 0.1 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EGE06231.1 - 0.021 15.1 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SMC_N PF02463.19 EGE06232.1 - 2.5e-70 236.3 0.0 1.2e-69 234.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGE06232.1 - 1.7e-20 73.4 1.1 1.3e-19 70.6 0.3 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGE06232.1 - 4.3e-09 36.6 10.0 0.00057 19.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE06232.1 - 0.001 18.8 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 EGE06232.1 - 0.0016 18.0 18.2 0.0016 18.0 18.2 5.6 3 2 2 5 5 5 1 Mechanosensitive ion channel porin domain HIP1_clath_bdg PF16515.5 EGE06232.1 - 0.0062 17.1 11.5 0.0062 17.1 11.5 8.9 3 2 6 10 10 10 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 EGE06232.1 - 0.07 13.6 0.1 0.07 13.6 0.1 5.5 4 2 0 4 4 4 0 ABC transporter SLATT_5 PF18160.1 EGE06232.1 - 4.8 6.5 11.9 0.11 11.8 0.5 3.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 CUE PF02845.16 EGE06233.1 - 4.2e-10 39.1 0.0 6.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EGE06233.1 - 0.0097 15.5 10.6 0.018 14.7 10.6 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) Sld5 PF05916.11 EGE06234.1 - 8.6e-33 113.1 0.0 2.1e-32 111.8 0.0 1.6 1 1 0 1 1 1 1 GINS complex protein DIE2_ALG10 PF04922.12 EGE06235.1 - 2.1e-110 369.7 9.3 2.5e-56 191.7 0.1 2.1 2 0 0 2 2 2 2 DIE2/ALG10 family FmiP_Thoc5 PF09766.9 EGE06236.1 - 1.4e-33 116.7 12.0 2e-33 116.2 12.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Casc1_N PF15927.5 EGE06236.1 - 0.0044 16.7 15.0 0.02 14.6 8.7 2.4 2 0 0 2 2 2 2 Cancer susceptibility candidate 1 N-terminus DUF948 PF06103.11 EGE06236.1 - 0.0099 16.1 1.5 0.37 11.1 0.0 2.9 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) SPATA1_C PF15743.5 EGE06236.1 - 0.012 15.7 3.3 0.012 15.7 3.3 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Flagellin_N PF00669.20 EGE06236.1 - 0.035 14.2 0.7 0.035 14.2 0.7 2.3 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region DUF4200 PF13863.6 EGE06236.1 - 0.039 14.3 14.0 0.044 14.2 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EGE06236.1 - 0.06 13.9 17.7 1.2 9.7 1.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DDE_Tnp_ISL3 PF01610.17 EGE06236.1 - 0.19 11.4 5.2 0.28 10.9 1.6 2.2 2 0 0 2 2 2 0 Transposase DUF349 PF03993.12 EGE06236.1 - 0.53 10.6 11.8 0.057 13.7 5.8 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1664 PF07889.12 EGE06236.1 - 1.6 8.8 5.2 16 5.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.6 EGE06236.1 - 2.8 7.5 17.9 2.6 7.6 3.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 EGE06236.1 - 2.8 8.6 11.4 5.4 7.7 2.1 2.6 2 1 0 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 EGE06236.1 - 5.7 7.4 10.7 9.7 6.7 0.6 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HlyIII PF03006.20 EGE06237.1 - 2.9e-61 207.1 22.1 3.5e-61 206.8 22.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 EGE06237.1 - 0.043 14.2 0.7 0.082 13.3 0.7 1.4 1 0 0 1 1 1 0 Acid shock protein repeat GlnD_UR_UTase PF08335.11 EGE06237.1 - 0.39 10.8 5.3 1.5 8.9 0.8 2.2 1 1 0 2 2 2 0 GlnD PII-uridylyltransferase Sugar_tr PF00083.24 EGE06238.1 - 5e-124 414.6 17.3 8.9e-124 413.8 17.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE06238.1 - 1.3e-26 93.4 47.0 7.9e-18 64.5 15.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_12 PF08242.12 EGE06239.1 - 1.2e-15 58.0 0.0 5.2e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE06239.1 - 5.8e-14 52.6 0.0 1.2e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06239.1 - 4.2e-12 46.6 0.0 1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE06239.1 - 7.2e-11 42.2 0.0 1.3e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06239.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE06239.1 - 4.3e-05 23.0 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EGE06239.1 - 0.0002 20.6 0.0 0.024 13.9 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EGE06239.1 - 0.0016 19.4 0.0 0.0033 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE06239.1 - 0.0018 17.8 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGE06239.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 EGE06239.1 - 0.065 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 EGE06239.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EGE06239.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EGE06239.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Diphthamide_syn PF01866.17 EGE06242.1 - 1.4e-85 287.4 0.0 2.7e-85 286.5 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein DUF1923 PF09083.10 EGE06242.1 - 0.054 13.2 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) PCM1_C PF15717.5 EGE06242.1 - 0.13 11.0 1.3 0.19 10.4 1.3 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Fe-ADH PF00465.19 EGE06243.1 - 6.4e-78 262.1 1.2 7.7e-78 261.8 1.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGE06243.1 - 6.8e-13 48.9 0.1 9.3e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ANAPC4_WD40 PF12894.7 EGE06244.1 - 1.9e-06 28.1 0.0 0.0019 18.5 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TLP-20 PF06088.11 EGE06244.1 - 0.016 15.1 2.2 0.024 14.5 2.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RR_TM4-6 PF06459.12 EGE06244.1 - 0.21 11.4 1.6 0.29 10.9 1.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PQQ_3 PF13570.6 EGE06244.1 - 0.37 11.3 4.7 4 8.1 0.1 3.9 3 1 1 4 4 4 0 PQQ-like domain CDC45 PF02724.14 EGE06244.1 - 0.45 8.7 7.3 0.63 8.3 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EGE06244.1 - 2.4 9.1 9.0 1.3e+02 3.7 0.3 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat FAM176 PF14851.6 EGE06244.1 - 3.2 7.4 4.9 5.3 6.7 4.9 1.3 1 0 0 1 1 1 0 FAM176 family PIG-S PF10510.9 EGE06245.1 - 2.5e-120 402.8 1.6 3.1e-120 402.4 1.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Orthoreo_P10 PF07204.11 EGE06246.1 - 0.055 13.4 0.2 0.73 9.8 0.0 2.5 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Sod_Fe_C PF02777.18 EGE06247.1 - 4.3e-18 65.4 0.0 1.6e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.20 EGE06248.1 - 1.1e-19 70.9 0.0 2.1e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1179 PF06678.11 EGE06249.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) JmjC PF02373.22 EGE06250.1 - 1.7e-07 31.7 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGE06250.1 - 2.8e-05 24.3 12.5 2.8e-05 24.3 12.5 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 EGE06250.1 - 9.6e-05 22.1 8.0 9.6e-05 22.1 8.0 2.8 2 1 0 2 2 2 1 Zinc finger, ZZ type Cupin_2 PF07883.11 EGE06250.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Baculo_IE-1 PF05290.11 EGE06250.1 - 0.19 11.7 8.4 0.04 13.9 1.6 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sulfatase PF00884.23 EGE06251.1 - 6.9e-22 78.2 0.2 1.4e-21 77.2 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EGE06251.1 - 8.5e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EGE06251.1 - 0.0056 15.3 0.0 0.0085 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Lyase_1 PF00206.20 EGE06252.1 - 1.5e-85 287.3 0.0 2.4e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EGE06252.1 - 1.7e-23 83.1 0.0 4.4e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CNOT1_HEAT PF16418.5 EGE06252.1 - 0.095 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat AMP-binding PF00501.28 EGE06253.1 - 2.6e-67 227.3 0.0 3.8e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE06253.1 - 4.8e-07 30.7 0.0 9.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M36 PF02128.15 EGE06254.1 - 3.2e-158 526.8 9.6 4.6e-158 526.2 9.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGE06254.1 - 4.5e-16 58.4 4.2 9.2e-16 57.4 4.2 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EGE06254.1 - 0.0002 21.3 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Aminotran_1_2 PF00155.21 EGE06255.1 - 1.1e-36 126.8 0.0 1.4e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE06255.1 - 1.6e-06 26.9 0.0 2.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGE06255.1 - 4.6e-06 26.1 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGE06255.1 - 4.9e-05 22.4 0.0 7.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGE06255.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.13 EGE06255.1 - 0.14 11.0 0.0 0.42 9.4 0.0 1.7 1 1 0 1 1 1 0 Allinase ABC2_membrane PF01061.24 EGE06256.1 - 3.6e-39 134.4 18.5 6.1e-39 133.6 18.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGE06256.1 - 6.9e-27 94.6 0.1 1.3e-26 93.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGE06256.1 - 3.9e-06 26.9 0.0 0.07 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EGE06256.1 - 9.9e-05 22.6 11.8 9.9e-05 22.6 11.8 3.3 3 0 0 3 3 2 2 EGF-like domain ABC2_membrane_3 PF12698.7 EGE06256.1 - 0.00065 18.9 26.1 0.0022 17.2 25.2 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EGE06256.1 - 0.0069 16.1 0.2 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGE06256.1 - 0.0093 16.5 0.1 0.022 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGE06256.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EGE06256.1 - 0.022 14.2 0.1 0.12 11.8 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE06256.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE06256.1 - 0.037 14.2 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGE06256.1 - 0.04 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGE06256.1 - 0.055 13.0 0.1 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGE06256.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.25 EGE06256.1 - 0.11 12.2 0.1 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EGE06256.1 - 0.17 11.5 0.0 0.77 9.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MFS_1 PF07690.16 EGE06257.1 - 1.1e-17 64.0 49.1 1.2e-16 60.6 30.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGE06257.1 - 4.4e-07 28.7 2.2 9.1e-07 27.6 2.2 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TerC PF03741.16 EGE06257.1 - 0.0075 16.0 0.1 0.0075 16.0 0.1 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family Cornichon PF03311.14 EGE06258.1 - 3e-50 169.6 13.3 3.4e-50 169.4 13.3 1.0 1 0 0 1 1 1 1 Cornichon protein NifU PF01106.17 EGE06260.1 - 1e-27 96.0 0.2 2.2e-27 95.0 0.1 1.6 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 EGE06260.1 - 2.6e-25 88.3 0.0 8.9e-25 86.6 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal RasGEF PF00617.19 EGE06261.1 - 3.6e-44 151.1 0.1 8.6e-44 149.8 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGE06261.1 - 5.7e-13 49.0 0.0 1.5e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_16 PF13191.6 EGE06261.1 - 0.011 16.1 0.2 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF2428 PF10350.9 EGE06261.1 - 0.053 12.8 0.2 0.14 11.4 0.2 1.7 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) ATP_bind_1 PF03029.17 EGE06261.1 - 0.17 11.6 0.1 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein zf-HIT PF04438.16 EGE06262.1 - 1.6e-09 37.5 7.9 2.4e-09 36.9 7.9 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 EGE06262.1 - 0.19 11.9 8.2 0.33 11.1 8.2 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF5320 PF17253.2 EGE06262.1 - 1.2 10.2 8.9 2.7 9.1 8.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DUF3446 PF11928.8 EGE06262.1 - 3.2 8.1 7.1 3.2 8.1 0.1 2.2 1 1 1 2 2 2 0 Early growth response N-terminal domain PolC_DP2 PF03833.13 EGE06262.1 - 3.4 5.4 5.4 3.8 5.2 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Complex1_LYR_2 PF13233.6 EGE06263.1 - 3.6e-22 78.9 0.4 4.4e-22 78.6 0.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like CHD5 PF04420.14 EGE06263.1 - 0.021 14.7 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 CHD5-like protein Cyclin_N PF00134.23 EGE06264.1 - 2.1e-11 43.6 0.0 4.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGE06264.1 - 4.4e-05 23.9 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin DUF3274 PF11678.8 EGE06265.1 - 0.05 12.9 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) CD24 PF14984.6 EGE06267.1 - 0.17 12.1 0.2 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 CD24 protein SBF PF01758.16 EGE06268.1 - 1.4e-53 181.5 12.2 1.4e-53 181.5 12.2 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family Kinocilin PF15033.6 EGE06268.1 - 0.88 9.2 2.7 1.2 8.8 0.6 2.4 2 0 0 2 2 2 0 Kinocilin protein DUF1240 PF06836.12 EGE06268.1 - 3.7 8.2 6.7 0.55 10.8 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) ATP_bind_3 PF01171.20 EGE06269.1 - 1.1e-18 67.7 0.0 1.6e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EGE06269.1 - 1.5e-18 66.0 5.4 1.5e-18 66.0 5.4 3.6 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EGE06269.1 - 0.043 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EGE06269.1 - 0.58 10.4 6.6 2 8.7 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RecR PF02132.15 EGE06269.1 - 1.8 8.2 10.2 0.054 13.1 1.6 2.7 3 0 0 3 3 3 0 RecR protein Acetyltransf_8 PF13523.6 EGE06270.1 - 4.5e-29 101.0 0.0 7.1e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_25 PF13649.6 EGE06272.1 - 1e-10 42.2 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06272.1 - 5.9e-07 29.4 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06272.1 - 4.3e-06 27.4 0.1 5.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE06272.1 - 1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06272.1 - 5.8e-05 23.7 0.0 0.00016 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE06272.1 - 0.00067 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGE06272.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGE06272.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGE06272.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_PK PF05891.12 EGE06272.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DREV PF05219.12 EGE06272.1 - 0.14 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF1992 PF09350.10 EGE06275.1 - 1.2e-19 70.2 0.3 3.7e-19 68.6 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 EGE06275.1 - 0.007 16.1 0.2 1.8 8.4 0.0 3.0 2 0 0 2 2 2 2 RPAP1-like, N-terminal ALGX PF16822.5 EGE06275.1 - 0.05 13.3 0.3 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX TcdB_N PF12918.7 EGE06275.1 - 1.2 9.4 3.6 0.82 10.0 0.2 2.5 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Hit1_C PF18268.1 EGE06276.1 - 0.091 12.9 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Hit1 C-terminal p450 PF00067.22 EGE06277.1 - 7.4e-51 173.3 0.0 1.9e-50 172.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.6 EGE06278.1 - 1.8e-09 37.6 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 EGE06279.1 - 2.2e-07 30.7 0.8 5.7e-07 29.3 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE06279.1 - 1.3e-05 24.9 0.1 3.4e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain Lactonase PF10282.9 EGE06279.1 - 0.093 12.0 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller SRP40_C PF05022.12 EGE06280.1 - 2.4e-18 66.8 0.1 9e-18 64.9 0.1 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3-PIP2_bind PF15277.6 EGE06281.1 - 1.8e-29 101.7 0.1 4e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EGE06281.1 - 9.5e-25 87.1 1.4 1.4e-24 86.5 1.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF3439 PF11921.8 EGE06281.1 - 3.9 7.5 7.0 9 6.3 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FAM176 PF14851.6 EGE06282.1 - 2.5e-05 24.0 3.1 2.7e-05 23.8 3.1 1.1 1 0 0 1 1 1 1 FAM176 family PTPRCAP PF15713.5 EGE06282.1 - 0.0032 17.8 11.5 0.0032 17.8 11.5 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 EGE06282.1 - 0.0041 16.4 4.7 0.0042 16.3 4.7 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 EGE06282.1 - 0.0061 16.5 4.7 0.0063 16.4 4.7 1.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EGE06282.1 - 0.014 14.7 17.5 0.016 14.6 17.5 1.0 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.6 EGE06282.1 - 0.041 14.3 20.1 0.047 14.1 20.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 GOLD_2 PF13897.6 EGE06282.1 - 0.055 14.0 3.2 0.078 13.5 3.2 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2722 PF10846.8 EGE06282.1 - 0.071 12.0 4.0 0.076 12.0 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sigma70_ner PF04546.13 EGE06282.1 - 0.079 12.8 12.5 0.085 12.7 12.5 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EGE06282.1 - 0.086 12.3 14.9 0.093 12.1 14.9 1.0 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EGE06282.1 - 0.1 10.7 19.7 0.1 10.7 19.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EGE06282.1 - 0.1 13.0 20.8 0.13 12.6 20.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RPA43_OB PF17875.1 EGE06282.1 - 0.12 13.0 4.8 0.12 13.0 4.8 1.1 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TLP-20 PF06088.11 EGE06282.1 - 0.19 11.6 6.8 0.22 11.4 6.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ORC_WH_C PF18137.1 EGE06282.1 - 0.2 11.7 8.1 0.24 11.5 8.1 1.0 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Paf1 PF03985.13 EGE06282.1 - 0.21 10.6 15.0 0.22 10.5 15.0 1.0 1 0 0 1 1 1 0 Paf1 Fmp27 PF10344.9 EGE06282.1 - 0.21 9.6 1.1 0.19 9.8 1.1 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 dsRBD2 PF17842.1 EGE06282.1 - 0.22 11.7 0.1 0.24 11.6 0.1 1.0 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Mpp10 PF04006.12 EGE06282.1 - 0.22 9.9 15.9 0.22 9.9 15.9 1.0 1 0 0 1 1 1 0 Mpp10 protein CPSF100_C PF13299.6 EGE06282.1 - 0.23 11.7 3.6 0.24 11.6 3.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFB6 PF17110.5 EGE06282.1 - 0.29 10.9 6.4 0.31 10.8 6.4 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2457 PF10446.9 EGE06282.1 - 0.32 10.1 19.2 0.31 10.2 19.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prothymosin PF03247.14 EGE06282.1 - 0.34 11.4 28.1 0.36 11.3 28.1 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family D123 PF07065.14 EGE06282.1 - 0.37 9.9 4.0 0.4 9.8 4.0 1.0 1 0 0 1 1 1 0 D123 RXT2_N PF08595.11 EGE06282.1 - 0.39 10.7 10.3 0.46 10.5 10.3 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 EGE06282.1 - 0.4 11.1 11.4 0.52 10.7 11.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF913 PF06025.12 EGE06282.1 - 0.41 9.6 3.5 0.42 9.5 3.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 EGE06282.1 - 0.5 9.7 5.5 0.48 9.8 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2428 PF10350.9 EGE06282.1 - 0.51 9.5 1.8 0.49 9.6 1.8 1.0 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Connexin PF00029.19 EGE06282.1 - 0.58 9.9 1.1 0.57 9.9 1.1 1.1 1 0 0 1 1 1 0 Connexin DUF1840 PF08895.11 EGE06282.1 - 0.62 10.4 4.7 0.72 10.2 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Nop14 PF04147.12 EGE06282.1 - 0.74 8.0 18.0 0.74 8.0 18.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF5520 PF17658.1 EGE06282.1 - 0.82 8.7 6.9 0.94 8.5 6.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5520) CDC45 PF02724.14 EGE06282.1 - 0.82 7.9 14.4 0.81 7.9 14.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SspB PF04386.13 EGE06282.1 - 0.95 9.3 6.8 1.1 9.2 6.8 1.1 1 0 0 1 1 1 0 Stringent starvation protein B AIM3 PF17096.5 EGE06282.1 - 0.95 10.4 5.5 1.1 10.2 5.5 1.1 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 TFIIF_alpha PF05793.12 EGE06282.1 - 1 7.9 17.6 1.1 7.8 17.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) THOC2_N PF16134.5 EGE06282.1 - 1 7.9 5.7 1.1 7.8 5.7 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RAB3GAP2_C PF14656.6 EGE06282.1 - 1.2 7.3 2.4 1.2 7.3 2.4 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RNA_pol_Rpc4 PF05132.14 EGE06282.1 - 1.4 9.3 4.8 1.6 9.2 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EGE06282.1 - 1.8 7.2 2.9 1.9 7.2 2.9 1.0 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 EGE06282.1 - 2.1 7.1 8.2 2.4 6.9 8.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 V_ATPase_I PF01496.19 EGE06282.1 - 2.1 6.1 2.8 2.2 6.1 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pox_Ag35 PF03286.14 EGE06282.1 - 2.3 8.0 14.3 2.5 7.9 14.3 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GRP PF07172.11 EGE06282.1 - 2.3 9.0 4.2 14 6.5 4.2 1.9 1 1 0 1 1 1 0 Glycine rich protein family CDC27 PF09507.10 EGE06282.1 - 2.3 7.5 11.9 2.3 7.5 11.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 EGE06282.1 - 2.8 7.2 15.0 3 7.1 15.0 1.0 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 EGE06282.1 - 3.3 5.7 10.9 3.6 5.5 10.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MAP17 PF15807.5 EGE06282.1 - 3.8 7.8 5.5 4.4 7.6 5.5 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RRN3 PF05327.11 EGE06282.1 - 4.1 5.8 10.6 4.3 5.8 10.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1682 PF07946.14 EGE06282.1 - 4.4 6.4 7.5 5 6.2 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PI3K_1B_p101 PF10486.9 EGE06282.1 - 4.5 4.9 7.9 4.6 4.9 7.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CobT PF06213.12 EGE06282.1 - 4.6 6.5 18.3 4.7 6.5 18.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT XAP5 PF04921.14 EGE06282.1 - 6.4 6.5 10.4 7.1 6.4 10.4 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Nop53 PF07767.11 EGE06282.1 - 8.1 5.7 17.6 8.9 5.6 17.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DOCK_N PF16172.5 EGE06283.1 - 8e-101 337.7 0.0 1.8e-100 336.5 0.0 1.6 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGE06283.1 - 1.2e-40 139.5 0.0 5.3e-40 137.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EGE06283.1 - 1.4e-39 136.2 5.5 4.3e-39 134.6 5.5 1.7 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EGE06283.1 - 3.9e-05 23.2 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE06283.1 - 0.00018 21.3 0.0 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGE06283.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Glyco_hydro_20 PF00728.22 EGE06284.1 - 1.5e-99 333.7 0.0 1.9e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGE06284.1 - 4.9e-17 62.9 0.0 2.1e-16 60.8 0.0 2.0 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGE06284.1 - 3.5e-05 24.6 0.0 6.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NmrA PF05368.13 EGE06285.1 - 1.1e-15 57.8 0.0 2.3e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EGE06285.1 - 2.2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_S8e PF01201.22 EGE06287.1 - 1.9e-55 186.8 1.4 2.2e-55 186.6 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribonuclease_T2 PF00445.18 EGE06288.1 - 6.3e-41 140.6 3.1 6.3e-41 140.6 1.6 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family GT-D PF08759.11 EGE06288.1 - 0.003 17.2 0.6 0.0045 16.7 0.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase GT-D fold Tissue_fac PF01108.17 EGE06288.1 - 0.99 9.3 5.0 5.6 6.9 0.1 2.4 1 1 1 2 2 2 0 Tissue factor Na_sulph_symp PF00939.19 EGE06289.1 - 1.4e-29 103.5 42.5 2e-29 103.0 42.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EGE06289.1 - 1.3e-27 96.8 63.1 7.7e-25 87.7 39.5 2.4 2 1 1 3 3 3 2 Citrate transporter SPX PF03105.19 EGE06289.1 - 7.4e-20 72.2 5.6 1.6e-10 41.5 0.0 2.1 1 1 1 2 2 2 2 SPX domain DUF4220 PF13968.6 EGE06289.1 - 0.0092 15.4 0.3 0.0092 15.4 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4220) Glycophorin_A PF01102.18 EGE06289.1 - 0.61 10.3 0.0 0.61 10.3 0.0 2.5 3 0 0 3 3 3 0 Glycophorin A Peptidase_S28 PF05577.12 EGE06290.1 - 1.3e-52 179.0 0.0 7.2e-52 176.6 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGE06290.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_S7 PF00177.21 EGE06292.1 - 2.6e-29 101.8 0.0 5.3e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1013 PF06242.11 EGE06292.1 - 0.01 15.9 0.6 0.23 11.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1013) Na_Ca_ex PF01699.24 EGE06293.1 - 2.6e-29 102.1 31.3 1.9e-20 73.3 15.5 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3810 PF12725.7 EGE06293.1 - 0.6 9.4 4.2 0.93 8.8 0.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3810) Cyt_bd_oxida_II PF02322.15 EGE06293.1 - 5.5 6.3 17.8 4.2 6.6 12.5 2.5 2 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II HNH_2 PF13391.6 EGE06295.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 EGE06296.1 - 2.9e-27 95.5 27.6 2.9e-27 95.5 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 EGE06297.1 - 2.1e-31 109.8 0.3 3e-31 109.3 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE06297.1 - 0.013 15.7 0.0 0.062 13.5 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGE06297.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE06297.1 - 0.1 12.6 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGE06297.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TadE PF07811.12 EGE06297.1 - 3.9 7.8 5.4 1.1 9.6 0.7 2.2 2 0 0 2 2 2 0 TadE-like protein Thioredoxin PF00085.20 EGE06298.1 - 2.2e-41 140.0 0.0 3.5e-24 84.8 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGE06298.1 - 6.4e-11 42.5 0.0 8.8e-05 22.5 0.0 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGE06298.1 - 0.00022 21.5 0.0 0.58 10.5 0.0 3.9 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGE06298.1 - 0.00028 21.3 0.8 1.2 9.6 0.1 3.8 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 EGE06298.1 - 0.0014 18.6 0.0 0.64 10.0 0.0 2.7 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EGE06298.1 - 0.024 14.7 0.9 0.55 10.3 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin domain Thioredoxin_7 PF13899.6 EGE06298.1 - 0.064 13.4 1.6 0.29 11.3 0.1 2.8 3 0 0 3 3 3 0 Thioredoxin-like TraF PF13728.6 EGE06298.1 - 0.17 11.7 7.6 0.39 10.5 0.0 3.6 4 0 0 4 4 4 0 F plasmid transfer operon protein ETC_C1_NDUFA5 PF04716.14 EGE06299.1 - 2e-26 91.6 6.6 1.7e-25 88.6 0.1 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region DUF1192 PF06698.11 EGE06299.1 - 0.39 10.8 4.3 0.73 9.9 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) Coatomer_WDAD PF04053.14 EGE06300.1 - 4.1e-170 566.6 0.0 9.3e-170 565.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGE06300.1 - 2e-38 129.7 4.5 2.9e-06 27.9 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06300.1 - 3.5e-06 27.2 0.0 4.6 7.6 0.0 5.8 3 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE06300.1 - 0.0011 17.8 2.4 0.25 9.9 0.3 3.7 1 1 0 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGE06300.1 - 0.091 12.8 0.0 13 5.9 0.0 3.5 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 EGE06301.1 - 1.8e-53 181.6 0.0 2.6e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06301.1 - 1.6e-23 83.3 0.0 2.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE06301.1 - 2.2e-06 26.9 0.0 3.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EGE06301.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 C2 domain APH PF01636.23 EGE06301.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 EGE06302.1 - 5.4e-10 39.3 0.0 1.8e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EGE06302.1 - 2.7e-09 37.2 0.0 7.5e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain PG_binding_1 PF01471.18 EGE06302.1 - 0.013 15.7 0.0 0.045 14.0 0.0 2.0 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF5112 PF17139.4 EGE06302.1 - 0.052 13.0 0.6 0.08 12.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) WD40 PF00400.32 EGE06304.1 - 1.5e-10 41.5 7.7 0.0088 16.9 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Glycos_transf_4 PF00953.21 EGE06305.1 - 8.8e-34 116.8 9.9 8.8e-34 116.8 9.9 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 EGE06305.1 - 8.9 4.5 11.6 6.4 4.9 10.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Aconitase PF00330.20 EGE06306.1 - 4.5e-165 550.1 0.0 5.7e-165 549.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGE06306.1 - 1.1e-40 139.0 0.0 1.9e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Pribosyltran PF00156.27 EGE06307.1 - 1.9e-14 53.5 0.2 3.1e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 EGE06308.1 - 4.4e-116 387.2 0.0 6.4e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.11 EGE06308.1 - 0.06 13.3 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DUF2418 PF10332.9 EGE06310.1 - 2.3e-35 121.0 0.2 5.3e-35 119.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 EGE06311.1 - 2.1e-33 114.5 0.0 2.4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EGE06312.1 - 5.6e-27 94.8 0.1 6.8e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGE06312.1 - 0.00051 20.4 0.0 0.00099 19.5 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Glyco_hydro_61 PF03443.14 EGE06312.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 CopC PF04234.12 EGE06312.1 - 0.093 13.8 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 CopC domain Alph_Pro_TM PF09608.10 EGE06312.1 - 0.18 11.6 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NOG1_N PF17835.1 EGE06313.1 - 2e-47 161.1 1.1 4.2e-47 160.1 0.1 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EGE06313.1 - 3.3e-29 100.6 1.5 7.9e-29 99.4 1.5 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EGE06313.1 - 3.5e-26 90.7 0.5 7.9e-26 89.6 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGE06313.1 - 1.6e-15 57.2 0.0 4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE06313.1 - 8.2e-08 31.9 0.0 3.1e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGE06313.1 - 0.00023 21.1 0.3 0.059 13.3 0.0 3.2 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EGE06313.1 - 0.0045 17.1 0.0 1.4 9.0 0.0 2.8 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 EGE06313.1 - 0.014 15.8 1.5 0.16 12.4 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EGE06313.1 - 0.15 12.3 0.0 0.96 9.7 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Acetyltransf_10 PF13673.7 EGE06314.1 - 6.6e-13 48.7 0.0 9.7e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE06314.1 - 8.7e-10 38.9 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE06314.1 - 2.2e-07 31.2 0.0 4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE06314.1 - 0.00029 20.7 0.0 0.00052 19.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.18 EGE06314.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 EGE06314.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2457 PF10446.9 EGE06314.1 - 0.22 10.6 8.0 0.31 10.2 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PGA2 PF07543.12 EGE06314.1 - 0.27 11.2 2.0 0.47 10.4 2.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 EGE06314.1 - 0.35 8.9 5.2 0.45 8.5 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EGE06314.1 - 0.39 11.1 10.4 0.77 10.2 10.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 EGE06314.1 - 0.86 9.0 3.1 1.1 8.6 3.1 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EGE06314.1 - 6.8 6.4 7.9 10 5.8 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp_protease PF09668.10 EGE06316.1 - 1.2e-61 205.9 0.2 1.8e-61 205.4 0.2 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGE06316.1 - 9.9e-23 80.5 0.0 1.8e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGE06316.1 - 1.3e-10 41.7 0.0 2.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 EGE06316.1 - 4.5e-08 32.7 0.0 7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGE06316.1 - 2.8e-07 30.3 0.0 5.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EGE06316.1 - 0.0025 17.6 0.1 0.0046 16.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.11 EGE06316.1 - 0.0036 17.1 0.1 0.0074 16.1 0.1 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EGE06316.1 - 0.029 14.7 0.0 0.066 13.5 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Rad60-SLD PF11976.8 EGE06316.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 EGE06316.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 NAD_binding_7 PF13241.6 EGE06316.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Zn_clus PF00172.18 EGE06317.1 - 3.3e-07 30.3 11.9 5.7e-07 29.5 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE06317.1 - 0.0057 15.5 0.0 0.045 12.6 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain GalP_UDP_transf PF01087.22 EGE06319.1 - 5.9e-69 232.2 0.1 8e-68 228.5 0.1 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EGE06319.1 - 1.9e-59 200.1 0.2 4.6e-59 198.9 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EGE06319.1 - 0.0031 16.4 0.0 0.15 10.9 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 EGE06319.1 - 0.14 12.6 0.0 0.43 11.1 0.0 1.8 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding WG_beta_rep PF14903.6 EGE06319.1 - 0.19 12.0 0.1 0.5 10.7 0.1 1.7 1 0 0 1 1 1 0 WG containing repeat Erg28 PF03694.13 EGE06320.1 - 1.6e-42 144.3 3.6 2e-42 144.0 3.6 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 EGE06321.1 - 5.5e-40 136.9 0.0 7.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE06321.1 - 4.9e-23 81.9 0.0 6.5e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE06321.1 - 1.7e-06 28.0 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGE06321.1 - 0.00048 19.6 0.0 0.00064 19.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGE06321.1 - 0.00063 19.0 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGE06321.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EGE06321.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EGE06322.1 - 2e-13 50.9 0.0 6.1e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE06322.1 - 2.4e-13 50.2 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06322.1 - 6.6e-13 49.1 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06322.1 - 4.1e-09 37.1 0.0 1.1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06322.1 - 2.6e-07 30.6 0.0 2.6e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE06322.1 - 0.00081 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EGE06322.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EGE06322.1 - 0.0012 18.2 0.0 0.0065 15.8 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGE06322.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EGE06322.1 - 0.071 12.4 0.0 0.35 10.1 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family KH_8 PF17903.1 EGE06323.1 - 6.9e-30 103.0 0.0 1.7e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain GCP_N_terminal PF17681.1 EGE06324.1 - 3.3e-64 217.4 0.0 5.6e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGE06324.1 - 6.1e-61 206.6 5.2 1.2e-60 205.6 5.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 EGE06325.1 - 3e-57 193.2 0.1 3.9e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGE06325.1 - 1.4e-12 47.0 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_8 PF05148.15 EGE06326.1 - 3.6e-47 161.0 3.2 6.6e-44 150.4 0.1 3.4 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EGE06326.1 - 0.02 14.9 1.2 0.053 13.5 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06326.1 - 0.045 14.4 0.1 0.27 11.9 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGE06326.1 - 0.066 13.9 0.0 3.8 8.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EGE06327.1 - 9.6e-69 231.7 0.0 1.4e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06327.1 - 6.1e-35 120.8 0.0 1.3e-34 119.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE06327.1 - 9.6e-06 25.1 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGE06327.1 - 0.003 17.0 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TetR_C_27 PF17935.1 EGE06327.1 - 0.058 13.5 0.0 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YrbL-PhoP_reg PF10707.9 EGE06327.1 - 0.091 12.3 1.4 0.28 10.7 0.0 2.5 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 EGE06329.1 - 8.4e-54 182.7 0.0 1.1e-53 182.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06329.1 - 6.6e-40 137.0 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE06329.1 - 0.0011 17.8 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGE06329.1 - 0.0034 16.8 0.0 0.0089 15.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE06329.1 - 0.0051 16.2 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE06329.1 - 0.0082 15.1 1.9 0.02 13.9 0.0 2.3 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 EGE06329.1 - 0.035 14.0 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.21 EGE06330.1 - 1.4e-08 34.3 0.0 0.00078 18.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGE06330.1 - 0.05 12.4 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Fungal_trans PF04082.18 EGE06331.1 - 4.3e-20 71.8 0.0 8.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 EGE06331.1 - 0.02 14.9 12.4 0.031 14.3 12.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EGE06331.1 - 0.035 14.5 3.3 0.069 13.6 3.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TF_Zn_Ribbon PF08271.12 EGE06331.1 - 0.038 13.5 0.1 0.071 12.6 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Spc7_N PF15402.6 EGE06331.1 - 0.12 10.7 4.0 0.16 10.2 4.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Ndc1_Nup PF09531.10 EGE06331.1 - 6 5.4 8.1 4.1 6.0 6.0 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Prefoldin_2 PF01920.20 EGE06332.1 - 4.7e-16 58.7 5.7 6.2e-14 51.8 0.1 2.0 1 1 1 2 2 2 2 Prefoldin subunit DASH_Dad3 PF08656.10 EGE06332.1 - 0.038 14.1 1.5 0.13 12.3 0.2 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2205 PF10224.9 EGE06332.1 - 0.048 13.7 0.7 0.048 13.7 0.7 1.6 2 0 0 2 2 2 0 Short coiled-coil protein FapA PF03961.13 EGE06332.1 - 0.074 11.6 3.0 0.078 11.6 3.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A CBFD_NFYB_HMF PF00808.23 EGE06334.1 - 1.5e-28 98.8 0.6 2.1e-28 98.4 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGE06334.1 - 6.3e-06 26.6 0.0 9.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGE06334.1 - 0.004 17.1 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EGE06334.1 - 0.0053 16.9 0.0 0.0075 16.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EGE06334.1 - 0.0058 16.6 0.0 0.0094 16.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 EGE06334.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A LysM PF01476.20 EGE06336.1 - 7.2e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain ADH_zinc_N_2 PF13602.6 EGE06337.1 - 7e-13 49.8 0.0 1.6e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE06337.1 - 1.6e-09 37.6 0.1 2.7e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE06337.1 - 8.2e-08 32.3 0.0 3.6e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DIOX_N PF14226.6 EGE06339.1 - 4e-23 82.4 0.0 7.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE06339.1 - 2.8e-10 40.6 0.0 5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 EGE06340.1 - 4.2e-47 160.8 35.6 1.8e-43 148.8 26.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE06340.1 - 0.00022 19.7 12.8 0.0013 17.1 8.3 2.9 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DIOX_N PF14226.6 EGE06342.1 - 5.8e-20 72.2 0.0 1e-19 71.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ketoacyl-synt PF00109.26 EGE06343.1 - 1.7e-74 250.6 0.0 3e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EGE06343.1 - 2.3e-50 171.6 0.7 1.1e-46 159.5 0.1 2.5 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Ketoacyl-synt_C PF02801.22 EGE06343.1 - 1.5e-33 115.3 0.4 1.5e-33 115.3 0.4 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EGE06343.1 - 2.5e-27 96.2 8.5 9.8e-24 84.4 0.1 3.4 4 0 0 4 4 4 2 Acyl transferase domain PP-binding PF00550.25 EGE06343.1 - 1.4e-14 54.2 0.1 4e-14 52.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGE06343.1 - 4.9e-11 43.1 0.2 2.2e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EGE06343.1 - 0.00042 19.8 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Trp_DMAT PF11991.8 EGE06344.1 - 3.3e-81 273.5 0.0 4.2e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Orexin PF02072.15 EGE06344.1 - 0.0035 17.3 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Prepro-orexin DUF4060 PF13269.6 EGE06344.1 - 0.12 12.4 0.1 16 5.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4060) FAD_binding_3 PF01494.19 EGE06345.1 - 8.7e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE06345.1 - 0.00066 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGE06345.1 - 0.0013 18.4 0.3 0.0035 17.0 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE06345.1 - 0.017 14.4 0.1 0.6 9.3 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGE06345.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGE06345.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EGE06345.1 - 0.11 11.8 0.0 4.4 6.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGE06345.1 - 0.11 11.8 0.0 2.5 7.3 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lactamase_B PF00753.27 EGE06346.1 - 2.1e-16 60.5 0.9 3.5e-10 40.2 0.2 2.3 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGE06346.1 - 0.00098 18.7 0.1 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EGE06346.1 - 0.0014 18.6 0.0 0.0054 16.7 0.0 2.1 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain Zn_clus PF00172.18 EGE06347.1 - 1.5e-07 31.4 7.1 2.8e-07 30.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE06347.1 - 0.00021 20.4 0.2 0.00078 18.5 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-PHD-like PF15446.6 EGE06347.1 - 0.013 15.1 1.6 0.026 14.1 1.6 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF1840 PF08895.11 EGE06347.1 - 0.099 13.0 0.3 1.5 9.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Metallophos PF00149.28 EGE06349.1 - 2.8e-06 28.0 1.6 5.3e-06 27.1 1.6 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S21 PF00716.17 EGE06350.1 - 0.001 18.8 0.2 0.0013 18.5 0.2 1.1 1 0 0 1 1 1 1 Assemblin (Peptidase family S21) Tyrosinase PF00264.20 EGE06351.1 - 2.7e-49 168.5 2.9 2.7e-49 168.5 2.9 2.0 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EGE06351.1 - 2.3e-27 96.1 0.0 3.8e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Tli4_N PF18443.1 EGE06351.1 - 0.075 13.4 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Fungal_trans PF04082.18 EGE06352.1 - 1.5e-21 76.7 2.9 2.3e-21 76.0 2.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.22 EGE06353.1 - 2.9e-47 160.3 2.0 4.2e-47 159.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 EGE06353.1 - 0.17 11.3 6.0 0.41 10.0 6.0 1.7 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 EGE06354.1 - 5.7e-09 36.2 0.0 8.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RIB43A PF05914.12 EGE06354.1 - 0.068 11.9 1.0 0.089 11.5 1.0 1.1 1 0 0 1 1 1 0 RIB43A CutA1 PF03091.15 EGE06354.1 - 0.084 12.7 0.4 0.19 11.6 0.2 1.6 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein Pkinase PF00069.25 EGE06355.1 - 2.9e-49 167.8 0.0 4.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06355.1 - 5.6e-18 65.2 0.0 8.8e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGE06355.1 - 0.00031 20.4 0.1 0.00083 19.0 0.1 1.7 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGE06355.1 - 0.00049 20.1 0.0 0.32 10.9 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE06355.1 - 0.012 15.0 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE06355.1 - 0.032 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF4648 PF15505.6 EGE06355.1 - 0.038 14.9 1.4 11 7.0 0.0 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4648) Pkinase_fungal PF17667.1 EGE06355.1 - 0.45 9.2 0.0 0.45 9.2 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase PWI PF01480.17 EGE06356.1 - 4.4e-32 110.2 0.1 6.5e-32 109.7 0.1 1.2 1 0 0 1 1 1 1 PWI domain C8 PF08742.11 EGE06357.1 - 0.6 10.6 5.5 0.39 11.2 2.5 2.1 1 1 1 2 2 2 0 C8 domain FAA_hydrolase PF01557.18 EGE06359.1 - 3.9e-30 105.1 0.1 5.1e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3584 PF12128.8 EGE06360.1 - 0.013 13.1 6.9 0.018 12.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 EGE06360.1 - 0.015 15.3 0.9 0.079 13.0 0.2 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nup54_57_C PF18570.1 EGE06360.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain TetR_C_24 PF17932.1 EGE06360.1 - 0.087 13.1 1.5 0.18 12.1 1.1 1.8 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TSC22 PF01166.18 EGE06360.1 - 0.091 13.1 0.6 1.6 9.1 0.1 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF2443 PF10398.9 EGE06360.1 - 0.17 12.0 0.1 1.4 9.0 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) Mis14 PF08641.12 EGE06360.1 - 0.2 12.0 6.2 0.12 12.6 3.3 2.3 2 1 0 2 2 2 0 Kinetochore protein Mis14 like Snapin_Pallidin PF14712.6 EGE06360.1 - 0.24 11.8 4.7 0.51 10.8 0.2 2.8 2 0 0 2 2 2 0 Snapin/Pallidin DUF883 PF05957.13 EGE06360.1 - 0.48 11.1 2.8 1.1 9.9 0.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Uso1_p115_C PF04871.13 EGE06360.1 - 1.1 9.7 5.8 6.1 7.2 0.5 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Apolipoprotein PF01442.18 EGE06360.1 - 2.5 8.0 13.2 3.3 7.5 10.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DEAD PF00270.29 EGE06361.1 - 7.5e-45 152.8 0.7 1.4e-44 151.9 0.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE06361.1 - 1.2e-31 109.3 0.3 4.1e-31 107.6 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE06361.1 - 7.5e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGE06361.1 - 5.6e-05 22.9 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE06361.1 - 0.00067 20.0 1.2 0.0046 17.3 0.7 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE06361.1 - 0.0038 17.5 0.4 0.019 15.2 0.4 2.2 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EGE06361.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EGE06361.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 EGE06361.1 - 0.095 12.4 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 EGE06361.1 - 0.12 12.4 0.2 0.71 9.8 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.6 EGE06362.1 - 1.8e-15 57.4 0.0 1.1e-13 51.6 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGE06362.1 - 2.8e-09 37.4 0.1 8.3e-08 32.7 0.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EGE06362.1 - 1e-06 28.5 0.0 2.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE06362.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EGE06362.1 - 0.064 13.8 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ctr PF04145.15 EGE06363.1 - 2.2e-25 90.0 11.2 3.6e-24 86.1 11.2 2.0 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.10 EGE06364.1 - 1.9e-27 94.9 0.1 1.9e-27 94.9 0.1 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_38N PF01074.22 EGE06365.1 - 4.4e-87 292.1 0.8 9.1e-87 291.1 0.8 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGE06365.1 - 1.3e-54 185.5 0.6 1.2e-53 182.4 0.3 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGE06365.1 - 2e-25 88.8 0.0 4e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGE06365.1 - 6.9e-09 35.7 0.0 1.7e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7TMR-DISMED2 PF07696.11 EGE06365.1 - 0.08 13.0 0.3 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 Glyco_hydro_57 PF03065.15 EGE06365.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Fucosidase_C PF16757.5 EGE06365.1 - 0.14 12.7 0.1 3.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Alpha-L-fucosidase C-terminal domain NUDIX PF00293.28 EGE06367.1 - 3.7e-09 36.7 0.1 1.4e-08 34.9 0.0 2.0 2 1 0 2 2 2 1 NUDIX domain PHINT_rpt PF14882.6 EGE06367.1 - 0.067 13.5 0.4 0.19 12.0 0.4 1.7 1 0 0 1 1 1 0 Phage-integrase repeat unit TRM13 PF05206.14 EGE06367.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 LETM1 PF07766.13 EGE06368.1 - 3.3e-103 344.7 0.1 5.8e-103 343.9 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EGE06368.1 - 0.0083 15.9 0.0 0.55 10.1 0.0 3.0 3 0 0 3 3 3 1 SAP domain DUF2838 PF10998.8 EGE06369.1 - 2.5e-39 133.9 11.0 2.5e-39 133.9 11.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Exonuc_VII_L PF02601.15 EGE06369.1 - 0.063 12.8 0.3 0.095 12.3 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.7 EGE06369.1 - 0.08 13.1 2.5 0.15 12.2 2.5 1.3 1 0 0 1 1 1 0 Tropomyosin like ApoLp-III PF07464.11 EGE06369.1 - 0.23 11.6 2.8 0.41 10.7 2.8 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.14 EGE06369.1 - 4.8 7.5 8.6 1.8 8.9 5.6 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.7 EGE06372.1 - 1.6e-26 92.7 0.4 1.5e-10 41.5 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE06372.1 - 1.8e-18 66.7 0.2 2.4e-05 24.8 0.0 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE06372.1 - 9.3e-18 64.1 1.7 2.3e-05 24.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE06372.1 - 9.1e-14 50.2 3.0 9.5e-05 22.5 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EGE06372.1 - 1.3e-09 38.1 3.6 0.00025 21.3 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat SMC_N PF02463.19 EGE06373.1 - 1.4e-59 201.2 0.1 3e-37 128.2 0.0 2.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGE06373.1 - 2.4e-30 105.2 1.0 1.4e-29 102.8 0.0 2.9 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EGE06373.1 - 3.6e-10 40.1 20.7 4.6e-05 23.4 0.0 4.5 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE06373.1 - 6.7e-08 32.2 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGE06373.1 - 7.4e-05 22.6 11.1 7.4e-05 22.6 11.1 4.9 2 2 2 4 4 2 1 AAA ATPase domain CALCOCO1 PF07888.11 EGE06373.1 - 0.0013 17.7 3.1 0.0013 17.7 3.1 5.2 3 2 1 5 5 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like SbcCD_C PF13558.6 EGE06373.1 - 0.003 17.8 0.0 0.031 14.5 0.0 2.8 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF4200 PF13863.6 EGE06373.1 - 0.006 17.0 5.4 0.006 17.0 5.4 8.9 4 3 6 10 10 6 4 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EGE06373.1 - 0.63 10.1 63.0 1.3 9.1 5.3 9.1 6 4 4 10 10 10 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EGE06373.1 - 2.7 8.5 40.6 2.8 8.5 2.4 8.7 7 1 2 9 9 9 0 Nucleopolyhedrovirus P10 protein Nbl1_Borealin_N PF10444.9 EGE06373.1 - 3.2 7.5 17.7 1.2 8.8 0.3 5.1 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal WH1 PF00568.23 EGE06374.1 - 0.1 12.6 0.1 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 WH1 domain acVLRF1 PF18859.1 EGE06374.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor E3_binding PF02817.17 EGE06375.1 - 4e-13 49.5 0.1 3.8e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 e3 binding domain NAD_Gly3P_dh_C PF07479.14 EGE06375.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Abhydrolase_2 PF02230.16 EGE06376.1 - 4.2e-20 72.5 0.0 2.1e-15 57.1 0.0 3.2 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Sulphotransf PF09037.10 EGE06376.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Stf0 sulphotransferase CM_1 PF07736.11 EGE06376.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Chorismate mutase type I HNH_2 PF13391.6 EGE06377.1 - 8.9e-15 54.6 0.1 1.5e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease WD40 PF00400.32 EGE06378.1 - 6.8e-24 83.7 13.8 0.00014 22.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06378.1 - 4e-14 52.7 6.5 0.00045 20.5 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE06378.1 - 8.8e-08 32.3 0.2 0.0074 16.2 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EGE06378.1 - 0.024 13.6 0.9 3.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGE06378.1 - 0.025 13.5 0.0 0.064 12.2 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M18 PF02127.15 EGE06379.1 - 2.2e-166 553.9 0.0 2.5e-166 553.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Sugar_tr PF00083.24 EGE06380.1 - 5.9e-23 81.4 16.9 9.7e-14 51.1 2.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGE06380.1 - 1.2e-22 80.3 20.9 4.9e-15 55.3 2.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 EGE06380.1 - 0.0018 16.7 0.1 0.0048 15.2 0.1 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFAP1 PF06991.11 EGE06380.1 - 0.97 9.2 7.1 1.8 8.4 7.1 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing FUN14 PF04930.15 EGE06380.1 - 5 7.6 6.4 1.3 9.5 1.0 2.6 2 1 0 2 2 2 0 FUN14 family Hydrolase_6 PF13344.6 EGE06381.1 - 9.9e-29 99.4 0.0 1.6e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE06381.1 - 6.4e-17 61.4 0.0 1.4e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGE06381.1 - 1.4e-11 45.1 0.2 2e-09 38.0 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGE06381.1 - 4.6e-07 30.1 0.2 0.019 15.0 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase UPF0253 PF06786.12 EGE06381.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) Acid_phosphat_B PF03767.14 EGE06381.1 - 0.052 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Mhr1 PF12829.7 EGE06382.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination UPF0561 PF10573.9 EGE06382.1 - 0.066 13.3 0.1 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF1746 PF08508.10 EGE06383.1 - 2.5e-43 147.1 0.4 3.4e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CLP_protease PF00574.23 EGE06384.1 - 2.2e-71 239.5 0.0 2.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Clp protease DHDPS PF00701.22 EGE06384.1 - 0.0052 15.5 0.0 0.0089 14.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Rep_fac_C PF08542.11 EGE06385.1 - 5.2e-24 84.5 0.1 1.3e-23 83.2 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGE06385.1 - 3.9e-12 46.7 0.0 1.2e-11 45.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGE06385.1 - 2.5e-11 43.6 0.0 3.2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EGE06385.1 - 3.9e-08 33.4 0.0 1.6e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGE06385.1 - 2.3e-05 24.6 0.3 9.1e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 EGE06385.1 - 0.00067 19.5 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGE06385.1 - 0.0008 19.2 0.0 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE06385.1 - 0.0013 19.2 0.1 0.031 14.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGE06385.1 - 0.0017 17.6 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGE06385.1 - 0.0019 17.6 0.0 0.08 12.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGE06385.1 - 0.0035 17.1 0.0 0.016 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE06385.1 - 0.0053 17.0 0.4 0.19 12.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGE06385.1 - 0.0078 16.6 0.0 0.055 13.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGE06385.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EGE06385.1 - 0.046 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MFS_1 PF07690.16 EGE06386.1 - 2.2e-42 145.3 50.0 2.2e-42 145.3 50.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE06386.1 - 1.4e-10 40.3 16.6 1.4e-10 40.3 16.6 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE06386.1 - 5.8e-10 38.6 13.6 5.8e-10 38.6 13.6 2.6 2 2 0 2 2 2 2 Sugar (and other) transporter DUF3522 PF12036.8 EGE06386.1 - 0.0018 18.6 2.3 0.0046 17.3 0.3 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3522) Sec20 PF03908.13 EGE06388.1 - 8e-05 22.5 2.6 0.31 11.0 0.2 2.8 2 0 0 2 2 2 2 Sec20 MRP_L53 PF10780.9 EGE06389.1 - 5.9e-14 52.0 0.1 7.8e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RPN5_C PF18098.1 EGE06389.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN5 C-terminal domain Pyrophosphatase PF00719.19 EGE06390.1 - 3.5e-57 192.7 0.1 4.5e-57 192.3 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 EGE06391.1 - 1.8e-42 145.5 0.0 4.4e-42 144.2 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.17 EGE06392.1 - 2.9e-43 147.9 0.1 5e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGE06392.1 - 4.6e-13 49.0 0.3 1.2e-12 47.6 0.3 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EGE06392.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EGE06392.1 - 0.048 12.7 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.23 EGE06393.1 - 8e-51 172.8 0.1 1.3e-50 172.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE06393.1 - 1.3e-19 70.6 0.4 2.1e-18 66.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE06393.1 - 2.5e-08 34.1 0.0 5.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGE06393.1 - 2.4e-06 27.0 0.1 4.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EGE06393.1 - 2.2e-05 24.3 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TRAM_LAG1_CLN8 PF03798.16 EGE06398.1 - 3.2e-34 118.4 13.8 3.8e-34 118.2 13.8 1.1 1 0 0 1 1 1 1 TLC domain MIP PF00230.20 EGE06398.1 - 0.027 14.2 0.2 0.037 13.7 0.2 1.3 1 0 0 1 1 1 0 Major intrinsic protein T_cell_tran_alt PF15128.6 EGE06398.1 - 0.94 9.3 2.9 0.98 9.3 0.3 2.1 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Hira PF07569.11 EGE06399.1 - 5.1e-79 265.1 0.0 1e-78 264.1 0.0 1.6 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EGE06399.1 - 4e-28 97.1 27.3 6.9e-05 23.5 0.0 9.7 8 1 1 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06399.1 - 1.4e-14 54.2 0.1 0.1 12.9 0.0 6.5 4 1 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGE06399.1 - 1.5e-10 40.7 0.1 4.2e-10 39.2 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EGE06399.1 - 1.7e-06 27.8 6.0 0.43 10.6 0.0 6.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EGE06399.1 - 0.00051 19.1 1.0 2.2 7.2 0.0 4.9 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EGE06399.1 - 0.0014 16.7 0.0 0.0039 15.3 0.0 1.6 1 1 1 2 2 2 1 IKI3 family YchF-GTPase_C PF06071.13 EGE06400.1 - 1.7e-33 114.6 0.1 3.9e-33 113.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGE06400.1 - 2e-17 63.3 0.0 8.4e-17 61.3 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE06400.1 - 0.00055 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EGE06400.1 - 0.011 15.8 0.1 0.041 13.9 0.1 2.0 2 1 0 2 2 2 0 TGS domain Glyco_hydro_79n PF03662.14 EGE06400.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain AAA_14 PF13173.6 EGE06400.1 - 0.13 12.4 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PUA PF01472.20 EGE06401.1 - 7.1e-14 51.5 0.3 1e-13 51.0 0.3 1.3 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 EGE06401.1 - 8.8e-12 45.6 1.3 5.7e-06 26.9 0.1 2.2 1 1 1 2 2 2 2 Pre-PUA-like domain DUF1947 PF09183.10 EGE06401.1 - 0.2 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) RIC1 PF07064.13 EGE06402.1 - 1e-78 264.2 0.0 1.7e-78 263.5 0.0 1.3 1 0 0 1 1 1 1 RIC1 SGTA_dimer PF16546.5 EGE06403.1 - 1.2e-23 82.6 0.1 2.2e-23 81.8 0.1 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EGE06403.1 - 5e-13 48.1 6.5 0.0011 18.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGE06403.1 - 7.2e-13 47.8 4.2 0.00014 21.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGE06403.1 - 6.4e-10 38.6 6.1 4.9e-07 29.3 0.7 3.0 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.6 EGE06403.1 - 8.4e-09 35.9 19.9 4.5e-06 27.2 5.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE06403.1 - 4.4e-06 26.5 4.3 0.33 11.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGE06403.1 - 3.7e-05 23.8 0.6 0.1 13.1 0.3 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE06403.1 - 4.9e-05 23.5 3.2 0.00085 19.6 0.6 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE06403.1 - 5.4e-05 23.7 7.0 0.099 13.5 0.7 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGE06403.1 - 0.00017 22.0 2.1 0.0013 19.2 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE06403.1 - 0.00022 21.0 0.2 15 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat STI1 PF17830.1 EGE06403.1 - 0.00027 20.8 11.6 0.0024 17.8 6.2 2.8 3 0 0 3 3 3 1 STI1 domain XPC-binding PF09280.11 EGE06403.1 - 0.00047 19.8 3.4 0.0016 18.1 3.3 1.9 2 0 0 2 2 2 1 XPC-binding domain TPR_9 PF13371.6 EGE06403.1 - 0.00057 20.0 1.7 0.0081 16.3 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGE06403.1 - 0.042 13.7 4.5 0.11 12.4 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GerD PF17898.1 EGE06403.1 - 0.17 11.8 1.3 0.84 9.6 0.4 2.4 2 0 0 2 2 2 0 Spore germination GerD central core domain DUF4264 PF14084.6 EGE06403.1 - 0.23 11.1 0.0 0.52 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) TPR_6 PF13174.6 EGE06403.1 - 0.76 10.5 5.2 10 7.0 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.15 EGE06404.1 - 9.4e-38 129.6 0.0 2.3e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain Spt20 PF12090.8 EGE06404.1 - 0.38 10.3 6.4 0.6 9.7 6.4 1.4 1 0 0 1 1 1 0 Spt20 family TRAP_alpha PF03896.16 EGE06404.1 - 5 6.3 6.6 1.5 7.9 2.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit VPS9 PF02204.18 EGE06405.1 - 2.2e-18 66.4 0.1 5.8e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EGE06405.1 - 7.2e-16 58.1 0.6 2.6e-13 49.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE06405.1 - 3.8e-11 43.4 0.0 0.0026 18.3 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE06405.1 - 8.2e-05 23.1 0.3 0.44 11.2 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE06405.1 - 9.1e-05 22.6 0.1 0.77 10.5 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 EGE06405.1 - 9.6e-05 22.3 0.6 0.00027 20.9 0.6 1.8 1 0 0 1 1 1 1 PX domain Ank PF00023.30 EGE06405.1 - 0.011 16.2 0.4 13 6.4 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ribosomal_S11 PF00411.19 EGE06405.1 - 0.052 13.9 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S11 Inhibitor_I78 PF11720.8 EGE06407.1 - 6.5e-13 48.5 0.0 7.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EGE06407.1 - 0.00016 22.2 0.1 0.00021 21.9 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.9 EGE06408.1 - 7.3e-32 109.8 11.4 7.3e-32 109.8 11.4 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EGE06408.1 - 0.00085 19.0 13.4 0.0011 18.7 13.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Golgin_A5 PF09787.9 EGE06408.1 - 1.1 8.7 12.4 1.7 8.0 12.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CK_II_beta PF01214.18 EGE06410.1 - 4.6e-78 261.2 0.1 6.4e-78 260.7 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RNA_pol_3_Rpc31 PF11705.8 EGE06410.1 - 0.0066 16.7 3.7 0.0098 16.2 3.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 zf-B_box PF00643.24 EGE06410.1 - 0.47 10.7 1.9 0.68 10.1 0.4 1.9 2 0 0 2 2 2 0 B-box zinc finger E1-E2_ATPase PF00122.20 EGE06411.1 - 7.9e-46 155.9 2.0 7.9e-46 155.9 2.0 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGE06411.1 - 8.4e-24 85.0 0.1 2e-23 83.8 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGE06411.1 - 6.6e-10 39.3 0.0 1.8e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGE06411.1 - 0.00021 21.1 0.1 0.63 9.7 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 EGE06411.1 - 0.00057 20.4 0.1 0.0019 18.7 0.1 2.0 1 0 0 1 1 1 1 CoA binding domain HAD PF12710.7 EGE06411.1 - 0.025 15.0 0.1 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EGE06412.1 - 1.2e-55 188.9 6.9 1.6e-55 188.5 6.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06412.1 - 5.1e-08 32.9 9.9 1.1e-07 31.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EGE06413.1 - 6.2e-07 29.5 0.4 1.7e-06 28.1 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EGE06413.1 - 0.04 14.0 0.4 0.062 13.4 0.4 1.4 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 EGE06413.1 - 0.042 14.5 2.6 0.055 14.1 2.6 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE06413.1 - 0.063 12.9 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 EGE06413.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) JAB PF01398.21 EGE06414.1 - 5.6e-08 32.8 0.3 3.8e-06 26.9 0.3 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trypan_PARP PF05887.11 EGE06415.1 - 0.0065 16.5 21.7 0.0065 16.5 21.7 16.6 7 4 8 16 16 16 3 Procyclic acidic repetitive protein (PARP) HMG_box PF00505.19 EGE06416.1 - 1.7e-06 28.3 4.0 1.7e-06 28.3 4.0 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGE06416.1 - 2.1e-05 25.0 3.3 2.1e-05 25.0 3.3 2.8 3 0 0 3 3 3 1 HMG-box domain Protamine_like PF06382.11 EGE06416.1 - 0.0051 17.0 1.1 0.0051 17.0 1.1 2.2 2 0 0 2 2 2 1 Protamine and protamine like DUF4662 PF15578.6 EGE06416.1 - 0.041 13.7 11.6 0.13 12.0 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) DEAD PF00270.29 EGE06417.1 - 3.1e-49 167.1 0.0 9.9e-49 165.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE06417.1 - 1e-26 93.4 0.0 3.5e-26 91.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE06417.1 - 0.0031 17.5 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WLM PF08325.10 EGE06418.1 - 0.0022 18.1 0.2 0.0022 18.1 0.2 1.4 2 0 0 2 2 2 1 WLM domain zf-C2H2 PF00096.26 EGE06419.1 - 9.9e-21 73.0 52.0 8.4e-07 29.1 0.9 8.6 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE06419.1 - 5.3e-14 51.9 45.5 6e-08 32.8 0.8 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-met PF12874.7 EGE06419.1 - 3.9e-13 49.3 4.8 0.00036 20.8 0.3 5.6 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGE06419.1 - 9.6e-12 44.7 51.5 0.00032 21.3 0.6 8.5 8 0 0 8 8 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE06419.1 - 1.1e-08 35.1 12.8 0.0046 17.2 0.3 5.6 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EGE06419.1 - 2.6e-06 27.1 6.0 0.072 12.9 0.2 4.7 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EGE06419.1 - 9.1e-06 25.5 20.4 0.00046 20.1 0.8 5.7 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EGE06419.1 - 0.00041 20.2 10.7 0.17 11.8 0.2 4.9 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EGE06419.1 - 0.00077 19.0 1.7 6.1 6.5 0.1 3.9 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EGE06419.1 - 0.019 15.2 16.5 0.047 14.0 0.5 4.2 4 0 0 4 4 3 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 EGE06419.1 - 0.022 15.4 0.2 0.022 15.4 0.2 7.6 5 4 2 7 7 6 0 FOXP coiled-coil domain BolA PF01722.18 EGE06419.1 - 0.76 10.1 0.1 0.76 10.1 0.1 3.6 4 1 1 5 5 4 0 BolA-like protein zf_ZIC PF18366.1 EGE06419.1 - 4.1 7.6 9.5 3.6 7.8 0.0 3.4 4 0 0 4 4 3 0 Zic proteins zinc finger domain Bac_DnaA PF00308.18 EGE06420.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein DUF533 PF04391.12 EGE06421.1 - 0.15 11.6 0.3 0.26 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) zf-C2H2 PF00096.26 EGE06422.1 - 2.1e-06 27.9 12.8 3.9e-05 23.9 3.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE06422.1 - 5.6e-06 26.5 3.2 5.6e-06 26.5 3.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE06422.1 - 0.0018 19.0 1.9 0.0018 19.0 1.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EGE06422.1 - 0.0019 18.5 0.9 0.0019 18.5 0.9 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGE06422.1 - 0.0056 16.6 3.1 0.0068 16.4 0.6 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE06422.1 - 0.014 15.7 0.9 0.047 14.0 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 EGE06422.1 - 0.018 14.7 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) IBR PF01485.21 EGE06422.1 - 0.058 13.6 1.8 0.12 12.7 1.8 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 EGE06422.1 - 0.063 13.6 5.6 0.15 12.4 5.6 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Podoplanin PF05808.11 EGE06427.1 - 0.0082 16.3 0.7 0.015 15.4 0.7 1.4 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 EGE06427.1 - 1.8 8.0 4.1 3.6 7.1 4.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAT PF02184.16 EGE06428.1 - 1.3e-24 85.9 79.2 1.9e-16 59.7 2.6 13.2 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGE06428.1 - 1.8e-18 65.7 25.2 0.00069 20.2 0.4 11.0 6 2 8 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGE06428.1 - 9e-18 64.6 0.1 4.4e-05 23.9 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 EGE06428.1 - 1.2e-12 48.4 32.7 0.00024 21.2 3.0 6.5 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EGE06428.1 - 2.5e-09 36.9 2.4 0.59 10.6 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGE06428.1 - 1e-06 28.5 3.7 12 6.4 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE06428.1 - 2.1e-05 24.9 16.9 0.73 10.6 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE06428.1 - 2.3e-05 24.1 15.9 0.36 11.1 0.0 7.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE06428.1 - 0.0011 19.6 8.0 1.3 9.8 0.0 6.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGE06428.1 - 0.024 14.8 2.1 4.4 7.5 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EGE06428.1 - 0.26 11.4 32.4 0.059 13.4 2.3 7.3 6 3 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 ER PF01133.17 EGE06428.1 - 0.35 10.9 2.9 5.3 7.1 0.6 3.8 3 1 1 4 4 4 0 Enhancer of rudimentary TPR_12 PF13424.6 EGE06428.1 - 2.6 8.4 18.2 8.2 6.8 0.1 6.7 6 2 1 7 7 7 0 Tetratricopeptide repeat Nop PF01798.18 EGE06429.1 - 3.7e-71 239.3 0.0 5.7e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGE06429.1 - 4.6e-47 159.9 1.6 9.3e-47 158.9 1.6 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain eIF-3c_N PF05470.12 EGE06429.1 - 0.055 11.8 0.6 0.079 11.3 0.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.11 EGE06429.1 - 2.4 6.6 7.1 3.3 6.1 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AdoHcyase PF05221.17 EGE06430.1 - 8.2e-118 392.9 0.0 9.1e-74 248.3 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGE06430.1 - 2e-69 232.8 1.0 4.7e-69 231.6 1.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGE06430.1 - 3.6e-07 29.7 0.1 6.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGE06430.1 - 8.7e-05 22.2 0.2 0.00016 21.3 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGE06430.1 - 0.0018 18.5 0.3 0.0041 17.4 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain DUF3759 PF12585.8 EGE06431.1 - 5.7e-38 128.8 9.3 6.7e-38 128.6 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Band_7_C PF16200.5 EGE06433.1 - 3.9e-23 81.3 1.6 3.9e-23 81.3 1.6 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7 PF01145.25 EGE06433.1 - 1.7e-21 77.0 0.2 1.7e-21 77.0 0.2 2.3 2 1 0 2 2 2 1 SPFH domain / Band 7 family Pox_A11 PF05061.13 EGE06433.1 - 0.05 12.9 0.3 0.078 12.2 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Mod_r PF07200.13 EGE06439.1 - 1.8e-25 89.7 0.5 2.2e-25 89.4 0.5 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 EGE06439.1 - 0.068 13.0 0.5 0.13 12.1 0.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor PSK_trans_fac PF07704.11 EGE06439.1 - 0.21 12.4 1.8 0.54 11.0 1.8 1.6 1 0 0 1 1 1 0 Rv0623-like transcription factor Cortex-I_coil PF09304.10 EGE06439.1 - 0.7 10.1 3.6 0.36 11.1 1.1 1.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil APG6_N PF17675.1 EGE06439.1 - 0.83 10.2 4.0 0.33 11.5 0.8 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region PAP2 PF01569.21 EGE06440.1 - 5.6e-25 87.7 0.2 5.6e-25 87.7 0.2 1.9 2 1 0 2 2 2 1 PAP2 superfamily Cupin_2 PF07883.11 EGE06442.1 - 0.12 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Cupin domain Peptidase_C14 PF00656.22 EGE06443.1 - 0.00021 21.3 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 EGE06443.1 - 0.0035 16.9 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Raptor_N PF14538.6 EGE06443.1 - 0.0056 16.6 0.0 0.036 14.0 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain Thi4 PF01946.17 EGE06443.1 - 0.13 11.5 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Aldo_ket_red PF00248.21 EGE06444.1 - 4.2e-50 170.6 0.1 6.9e-50 169.9 0.1 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 EGE06445.1 - 8.2e-09 35.4 7.3 1.2e-08 34.9 7.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EGE06446.1 - 2.6e-66 223.7 0.0 3e-65 220.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06446.1 - 1.2e-33 116.5 0.0 1.2e-32 113.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EGE06446.1 - 2.9e-32 110.9 0.2 6.4e-32 109.7 0.2 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EGE06446.1 - 2.3e-05 23.9 0.0 3.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE06446.1 - 0.00045 19.3 0.0 0.0012 17.9 0.0 1.8 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGE06446.1 - 0.0044 16.4 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE06446.1 - 0.047 13.6 0.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DAO PF01266.24 EGE06448.1 - 6.8e-13 48.9 0.0 9.6e-06 25.4 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE06448.1 - 0.0026 17.1 0.0 0.0036 16.6 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE06448.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EGE06448.1 - 0.15 11.3 0.0 0.58 9.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family DUF1690 PF07956.11 EGE06449.1 - 6.8e-39 133.5 5.2 3e-19 69.8 2.4 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EGE06449.1 - 0.018 15.1 1.3 0.18 11.8 0.3 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion POP1 PF06978.11 EGE06450.1 - 2.2e-74 249.9 16.3 4.3e-74 248.9 16.3 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGE06450.1 - 8.5e-33 112.6 1.7 8.5e-33 112.6 1.7 2.1 2 0 0 2 2 2 1 POPLD (NUC188) domain Redoxin PF08534.10 EGE06451.1 - 2.2e-37 128.0 0.0 2.5e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGE06451.1 - 1.7e-11 44.1 0.0 2.1e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.16 EGE06452.1 - 2.5e-74 249.7 0.0 3.4e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EGE06452.1 - 2e-72 243.3 0.0 3e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Acyl-CoA_dh_2 PF08028.11 EGE06453.1 - 0.031 14.6 0.6 0.057 13.7 0.6 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Lin-8 PF03353.15 EGE06453.1 - 6.4 6.2 6.5 3.6 7.0 4.3 1.7 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Phospholip_A2_3 PF09056.11 EGE06454.1 - 8.3e-40 135.9 4.9 9.8e-40 135.7 4.9 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 DUF604 PF04646.12 EGE06456.1 - 1.5e-08 34.3 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EGE06456.1 - 0.00084 18.9 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 Fringe-like GDI PF00996.18 EGE06457.1 - 3e-26 91.9 0.0 2.9e-25 88.7 0.0 2.2 1 1 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.21 EGE06458.1 - 5.2e-55 186.0 0.0 5.8e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 EGE06459.1 - 2e-44 152.2 0.1 1.1e-43 149.8 0.0 2.1 1 1 1 2 2 2 1 Signal peptide peptidase SPP PF06550.11 EGE06459.1 - 4.3e-05 23.1 3.2 0.00013 21.6 3.2 1.7 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease RNase_PH PF01138.21 EGE06460.1 - 9.4e-17 61.8 0.8 4.2e-15 56.4 0.8 2.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.12 EGE06462.1 - 1.5e-19 70.7 0.0 4.9e-19 69.0 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGE06462.1 - 1.6e-17 63.8 9.8 1.6e-17 63.8 9.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGE06462.1 - 2.2e-14 53.4 0.0 6.3e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EGE06462.1 - 0.0081 16.8 0.0 6.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EGE06462.1 - 0.013 16.0 1.0 0.013 16.0 1.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) DUF2975 PF11188.8 EGE06462.1 - 0.17 11.7 0.0 0.17 11.7 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) Acetyltransf_7 PF13508.7 EGE06463.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE06463.1 - 0.046 14.0 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Sgf11 PF08209.11 EGE06464.1 - 3.2e-07 29.8 3.7 7.9e-07 28.5 0.1 2.6 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) EamA PF00892.20 EGE06465.1 - 0.3 11.2 5.2 0.11 12.6 1.1 2.2 3 0 0 3 3 3 0 EamA-like transporter family Tetraspanin PF00335.20 EGE06465.1 - 5.6 6.6 9.9 33 4.1 9.9 2.4 1 1 0 1 1 1 0 Tetraspanin family Lactonase PF10282.9 EGE06466.1 - 2.2e-86 290.2 0.0 2.7e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Mg_trans_NIPA PF05653.14 EGE06467.1 - 7.5e-12 45.0 6.4 5.8e-09 35.5 2.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA TMEM61 PF15105.6 EGE06467.1 - 0.035 14.0 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 TMEM61 protein family EamA PF00892.20 EGE06467.1 - 0.31 11.2 12.4 1.1 9.4 0.1 2.8 3 0 0 3 3 3 0 EamA-like transporter family Neurensin PF14927.6 EGE06467.1 - 0.65 9.7 2.8 31 4.3 0.1 3.3 3 0 0 3 3 3 0 Neurensin vATP-synt_E PF01991.18 EGE06468.1 - 2.7e-59 199.9 11.2 3.2e-59 199.7 11.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 EGE06468.1 - 0.014 15.7 5.1 4.6 7.7 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) IFS PF16718.5 EGE06468.1 - 0.066 13.3 0.7 0.33 11.0 0.5 1.9 2 0 0 2 2 2 0 Immunity factor for SPN PhoLip_ATPase_C PF16212.5 EGE06472.1 - 2e-76 257.0 19.3 2e-76 257.0 19.3 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGE06472.1 - 4.7e-19 67.8 1.4 9.9e-19 66.8 1.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGE06472.1 - 2.9e-12 46.5 0.0 1.4e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE06472.1 - 1.1e-10 42.2 0.6 1.5e-05 25.4 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGE06472.1 - 8.3e-05 22.2 0.1 0.00033 20.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGE06472.1 - 0.026 14.3 0.2 0.059 13.1 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 EGE06473.1 - 1e-153 513.4 4.6 1.2e-148 496.7 0.8 2.2 1 1 1 2 2 2 2 SEN1 N terminal AAA_11 PF13086.6 EGE06473.1 - 5e-57 193.7 2.9 5e-57 193.7 2.9 2.5 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EGE06473.1 - 1.9e-44 151.7 0.0 5e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGE06473.1 - 6.4e-06 26.0 0.2 1.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EGE06473.1 - 5.2e-05 22.9 1.7 5.2e-05 22.9 1.7 2.8 3 1 0 3 3 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGE06473.1 - 0.00014 22.3 0.1 0.00049 20.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain zf-CCHC PF00098.23 EGE06473.1 - 0.0021 18.1 1.3 0.0021 18.1 1.3 3.5 3 0 0 3 3 2 2 Zinc knuckle DEAD PF00270.29 EGE06473.1 - 0.0021 17.8 0.2 0.0091 15.8 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 EGE06473.1 - 0.0084 15.2 0.0 0.024 13.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EGE06473.1 - 0.012 15.4 0.0 5 6.8 0.0 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EGE06473.1 - 0.02 14.9 0.1 0.15 12.1 0.0 2.6 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGE06473.1 - 0.095 13.0 0.0 2.2 8.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain Med9 PF07544.13 EGE06473.1 - 0.097 12.8 1.9 0.42 10.7 1.9 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Sigma70_r1_1 PF03979.14 EGE06473.1 - 0.29 11.2 2.1 0.56 10.3 0.8 2.2 2 0 0 2 2 1 0 Sigma-70 factor, region 1.1 zf-CCHC_5 PF14787.6 EGE06473.1 - 0.48 10.2 16.7 0.063 13.0 0.7 3.2 2 1 1 3 3 2 0 GAG-polyprotein viral zinc-finger HAUS6_N PF14661.6 EGE06473.1 - 2.4 7.7 11.2 0.31 10.6 5.8 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus zf-CCHC_2 PF13696.6 EGE06473.1 - 4 7.4 7.2 2 8.3 1.0 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF4164 PF13747.6 EGE06473.1 - 7 7.0 7.9 7.2 7.0 5.4 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) AAA_23 PF13476.6 EGE06473.1 - 9.7 6.6 7.6 0.64 10.5 1.2 2.3 2 0 0 2 2 1 0 AAA domain CAP59_mtransfer PF11735.8 EGE06474.1 - 9.5e-70 235.0 0.0 4.5e-69 232.8 0.0 1.9 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 SUIM_assoc PF16619.5 EGE06474.1 - 2.3 8.3 7.7 5.7 7.1 7.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CorA PF01544.18 EGE06477.1 - 1.8e-09 37.3 0.5 4e-09 36.2 0.5 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 EGE06477.1 - 0.045 13.1 0.2 0.07 12.4 0.2 1.3 1 0 0 1 1 1 0 Apolipoprotein L WH1 PF00568.23 EGE06478.1 - 6.9e-29 100.0 0.0 1.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 WH1 domain eIF-1a PF01176.19 EGE06480.1 - 4.7e-22 77.6 0.0 6.5e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.15 EGE06481.1 - 1.4e-18 67.6 0.0 6.1e-18 65.5 0.0 2.2 3 0 0 3 3 3 1 ERCC4 domain HHH_5 PF14520.6 EGE06481.1 - 0.097 13.3 0.2 0.78 10.4 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain fn3_2 PF16893.5 EGE06482.1 - 7.6e-38 128.6 0.1 1.3e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EGE06482.1 - 7.3e-24 83.5 0.5 1.4e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EGE06482.1 - 1.4e-14 53.8 0.0 2.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EGE06482.1 - 1.7e-07 31.5 0.0 3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EGE06482.1 - 1.3e-05 25.3 0.0 4.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EGE06482.1 - 4e-05 23.9 0.0 8.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EGE06482.1 - 0.0022 18.3 0.0 0.0084 16.4 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain Peptidase_S10 PF00450.22 EGE06483.1 - 6.3e-75 253.2 0.0 1.1e-74 252.4 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_7 PF13508.7 EGE06484.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE06484.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE06484.1 - 0.088 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.25 EGE06485.1 - 1.3e-08 35.1 0.0 2.2e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE06485.1 - 5.4e-07 29.6 0.0 2.2e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE06485.1 - 1.2e-05 25.6 0.0 2.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE06485.1 - 8.2e-05 22.7 0.1 0.001 19.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGE06485.1 - 0.01 16.0 0.0 0.056 13.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE06485.1 - 0.043 13.8 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.6 EGE06485.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GFA PF04828.14 EGE06486.1 - 6.3e-11 42.5 0.5 1.4e-05 25.3 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 EGE06487.1 - 2.1e-47 161.8 36.5 2.1e-47 161.8 36.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06487.1 - 4.1e-11 42.4 11.1 4.1e-11 42.4 11.1 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EGE06487.1 - 4.2e-06 25.5 1.8 4.2e-06 25.5 1.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4614 PF15391.6 EGE06487.1 - 0.22 11.5 1.5 2.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) MFS_1 PF07690.16 EGE06488.1 - 1.5e-19 70.2 60.3 2.2e-17 63.0 54.5 3.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE06488.1 - 1.4e-08 33.7 29.8 1.7e-08 33.4 15.8 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE06488.1 - 6.5e-07 28.6 38.3 6.6e-06 25.2 15.0 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2109 PF09882.9 EGE06488.1 - 3.6 7.7 9.0 0.4 10.7 1.3 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Evr1_Alr PF04777.13 EGE06489.1 - 5.4e-12 46.1 0.0 7.6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family zf-LYAR PF08790.11 EGE06490.1 - 2.6e-13 49.6 2.8 2.6e-13 49.6 2.8 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger RNHCP PF12647.7 EGE06490.1 - 1.3 9.0 5.2 3.9 7.5 5.2 1.8 1 1 0 1 1 1 0 RNHCP domain R3H PF01424.22 EGE06491.1 - 5.3e-13 48.7 0.0 4.9e-12 45.7 0.1 2.3 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 EGE06491.1 - 0.00019 21.4 80.5 0.00073 19.5 14.5 14.4 15 2 1 16 16 16 7 NF-X1 type zinc finger Pkinase PF00069.25 EGE06492.1 - 6.1e-06 25.8 0.1 1.6e-05 24.4 0.1 1.6 1 1 1 2 2 2 1 Protein kinase domain CDC45 PF02724.14 EGE06493.1 - 4.9 5.3 5.7 4.9 5.3 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein ARID PF01388.21 EGE06494.1 - 3.6e-18 66.0 0.0 8.2e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain CDK2AP PF09806.9 EGE06494.1 - 5.7 6.9 11.1 10 6.1 11.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Img2 PF05046.14 EGE06496.1 - 6.4e-26 90.5 0.0 9e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 EGE06497.1 - 1.8e-48 164.4 2.4 3.1e-48 163.6 2.4 1.4 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGE06497.1 - 6.7e-07 29.8 0.0 2.1e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain DUF445 PF04286.12 EGE06497.1 - 0.27 11.0 2.9 0.85 9.4 2.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) ArsA_ATPase PF02374.15 EGE06500.1 - 3.9e-113 377.7 0.0 4.5e-113 377.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EGE06500.1 - 1.1e-13 51.4 0.3 4.4e-12 46.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EGE06500.1 - 1.6e-12 47.6 0.0 3.2e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EGE06500.1 - 6.7e-06 25.7 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EGE06500.1 - 6.9e-06 25.7 0.9 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EGE06500.1 - 1.5e-05 24.7 0.2 0.00065 19.4 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EGE06500.1 - 9e-05 22.1 0.0 0.00029 20.4 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EGE06500.1 - 0.058 12.8 0.0 0.15 11.5 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EGE06500.1 - 0.077 12.2 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EGE06500.1 - 0.16 12.5 0.0 0.9 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGE06500.1 - 0.21 11.2 0.1 0.73 9.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ferric_reduct PF01794.19 EGE06501.1 - 1.8e-20 73.3 16.7 1.8e-20 73.3 16.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EGE06501.1 - 2e-16 60.5 0.0 3.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGE06501.1 - 8.4e-07 29.1 0.0 0.043 13.9 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EGE06501.1 - 0.065 13.9 0.0 2.3 8.9 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Transthyretin PF00576.21 EGE06502.1 - 2.6e-29 102.1 0.0 3.5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRR PF11787.8 EGE06503.1 - 1.9e-18 67.4 1.7 1.9e-18 67.4 1.7 4.1 3 1 1 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 EGE06503.1 - 3.3e-18 65.8 11.6 3.3e-18 65.8 11.6 3.5 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 EGE06503.1 - 1.4e-14 54.2 7.1 2.1e-14 53.7 4.0 2.9 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EGE06503.1 - 5.8e-08 32.7 10.7 9.4e-08 32.0 10.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGE06503.1 - 0.0032 17.5 9.7 0.0063 16.6 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGE06503.1 - 0.045 14.3 4.7 0.09 13.3 4.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HeLo PF14479.6 EGE06503.1 - 0.1 12.5 0.9 0.16 11.8 0.9 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF615 PF04751.14 EGE06503.1 - 0.11 12.4 1.8 0.19 11.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Nop53 PF07767.11 EGE06503.1 - 0.19 11.1 13.5 0.29 10.5 13.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PARP PF00644.20 EGE06504.1 - 1.1e-10 41.4 0.2 2.2e-10 40.5 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 EGE06504.1 - 3.7e-08 33.1 0.0 7.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGE06504.1 - 0.018 15.3 0.0 0.084 13.2 0.0 2.1 2 0 0 2 2 2 0 RWD domain DASH_Spc19 PF08287.11 EGE06506.1 - 0.033 14.1 0.6 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Spc19 Nop PF01798.18 EGE06507.1 - 1.6e-83 279.7 0.5 1.6e-83 279.7 0.5 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGE06507.1 - 1.2e-21 76.9 1.1 1.2e-21 76.9 1.1 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.16 EGE06508.1 - 6.8e-109 364.4 0.0 7.6e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.6 EGE06509.1 - 2.7e-36 125.3 2.3 8.1e-32 110.7 0.8 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EGE06509.1 - 8.4e-34 116.0 0.0 2e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGE06509.1 - 8.8e-14 51.3 0.3 1.8e-13 50.3 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGE06509.1 - 0.00044 19.8 0.2 0.00068 19.1 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YukD PF08817.10 EGE06510.1 - 0.0027 18.4 0.0 0.0042 17.7 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 EGE06510.1 - 0.0027 17.4 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Presenilin PF01080.17 EGE06510.1 - 3.9 6.1 3.9 4.2 6.0 3.9 1.2 1 0 0 1 1 1 0 Presenilin PIG-H PF10181.9 EGE06511.1 - 7.2e-27 93.1 0.3 1.6e-26 91.9 0.3 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EGE06512.1 - 7.8e-10 39.2 0.0 4.1e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pox_A_type_inc PF04508.12 EGE06512.1 - 0.0036 17.1 0.2 0.0095 15.7 0.2 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Amidoligase_2 PF12224.8 EGE06513.1 - 2e-07 31.0 0.0 2.9e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.20 EGE06514.1 - 5.1e-26 91.2 0.1 3e-14 52.8 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EGE06514.1 - 3.1e-05 25.3 20.6 5.8e-05 24.4 20.6 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EGE06515.1 - 8.8e-25 86.7 1.3 2.9e-24 85.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Hanta_nucleocap PF00846.18 EGE06515.1 - 0.0013 17.3 0.8 0.0017 16.9 0.2 1.5 2 0 0 2 2 2 1 Hantavirus nucleocapsid protein DEAD PF00270.29 EGE06517.1 - 3.7e-38 131.0 0.0 2.3e-37 128.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGE06517.1 - 0.0017 18.4 0.0 0.0033 17.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGE06517.1 - 0.006 16.9 0.2 0.065 13.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain GARS_N PF02844.15 EGE06517.1 - 0.16 12.8 0.0 0.31 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain XPG_I PF00867.18 EGE06519.1 - 5.2e-22 78.0 0.1 1.2e-21 76.8 0.1 1.7 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EGE06519.1 - 5.6e-16 59.3 0.2 5.6e-16 59.3 0.2 2.4 1 1 1 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EGE06519.1 - 8.8e-08 32.5 0.0 2.1e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGE06519.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing 5_3_exonuc_N PF02739.16 EGE06519.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Actin PF00022.19 EGE06520.1 - 3.8e-22 78.5 0.0 4.8e-19 68.2 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EGE06520.1 - 0.11 11.3 0.0 0.36 9.6 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Aldose_epim PF01263.20 EGE06522.1 - 2.9e-44 151.6 0.3 3.8e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase BRCT PF00533.26 EGE06522.1 - 0.046 14.1 0.0 0.22 11.9 0.0 2.1 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 EGE06524.1 - 1.5e-13 50.7 0.0 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06524.1 - 4.7e-10 39.2 0.0 1.9e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Sec34 PF04136.15 EGE06526.1 - 3.2e-49 166.6 0.1 8.1e-49 165.3 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family Mannitol_dh_C PF08125.13 EGE06529.1 - 6.9e-41 140.4 0.1 1.6e-40 139.2 0.0 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EGE06529.1 - 2.4e-18 66.7 0.5 5e-18 65.7 0.2 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EGE06529.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain L31 PF09784.9 EGE06529.1 - 0.19 12.2 0.5 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 RNA_pol_Rpc34 PF05158.12 EGE06529.1 - 1.2 8.5 4.5 0.8 9.0 0.8 2.2 2 1 1 3 3 3 0 RNA polymerase Rpc34 subunit RCC1 PF00415.18 EGE06530.1 - 2.5e-33 114.4 6.9 8.1e-07 29.6 0.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGE06530.1 - 1.3e-13 50.4 24.1 3.9e-05 23.3 0.3 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 EGE06531.1 - 2.3e-50 171.4 0.0 3e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Sushi_2 PF09014.10 EGE06531.1 - 0.063 13.2 0.2 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Pkinase PF00069.25 EGE06532.1 - 4.2e-63 213.2 0.0 6.3e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06532.1 - 2e-43 148.5 0.0 3.3e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE06532.1 - 2.2e-10 40.4 0.0 6.7e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGE06532.1 - 0.0026 16.6 0.0 0.007 15.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGE06532.1 - 0.0029 17.0 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RepL PF05732.11 EGE06532.1 - 0.054 12.9 0.1 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) APH PF01636.23 EGE06532.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family eIF3_p135 PF12807.7 EGE06533.1 - 8.1 6.4 14.8 26 4.8 0.2 4.7 3 2 2 5 5 5 0 Translation initiation factor eIF3 subunit 135 GCP_C_terminal PF04130.13 EGE06534.1 - 2.3e-93 313.0 0.0 4.5e-93 312.1 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGE06534.1 - 1.6e-80 271.0 0.0 1.5e-79 267.8 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Mre11_DNA_bind PF04152.14 EGE06534.1 - 0.2 12.0 0.1 0.43 10.9 0.1 1.5 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain DUF2373 PF10180.9 EGE06535.1 - 2e-21 75.5 0.1 3.6e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 EGE06536.1 - 3.9e-48 163.5 0.0 5.5e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGE06536.1 - 4.6e-13 48.6 0.3 8.3e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 EGE06536.1 - 0.041 14.4 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family Amidase_5 PF05382.13 EGE06536.1 - 0.057 13.3 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Rbx_binding PF18113.1 EGE06537.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain PTR2 PF00854.21 EGE06541.1 - 5.1e-92 308.7 8.1 9.5e-92 307.8 8.1 1.4 1 1 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.28 EGE06542.1 - 4.4e-88 296.0 1.4 5.1e-88 295.8 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 EGE06543.1 - 5.7e-34 115.7 0.7 9.7e-34 115.0 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGE06543.1 - 1.5e-26 92.3 1.9 1.5e-26 92.3 1.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGE06543.1 - 4.1e-16 58.6 0.8 7.4e-16 57.7 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGE06543.1 - 2.5e-05 24.7 0.2 0.00013 22.4 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGE06543.1 - 0.00085 19.4 0.6 0.0019 18.3 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGE06543.1 - 0.0061 16.5 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGE06543.1 - 0.0081 16.5 0.9 0.013 15.8 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 EGE06543.1 - 0.0086 16.6 0.9 0.012 16.1 0.9 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.21 EGE06543.1 - 0.013 15.7 0.3 0.021 15.0 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 EGE06543.1 - 0.023 14.7 1.1 6.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zf-H2C2_2 PF13465.6 EGE06544.1 - 2e-09 37.4 5.1 0.0013 19.1 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EGE06544.1 - 3e-07 30.5 17.1 0.00099 19.4 4.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE06544.1 - 5.9e-06 26.7 14.7 0.0071 17.1 3.4 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGE06544.1 - 0.051 13.6 7.1 1.3 9.1 2.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGE06544.1 - 0.16 11.7 7.2 0.085 12.6 2.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EGE06544.1 - 0.17 12.4 1.4 0.45 11.0 1.4 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EGE06544.1 - 1.3 9.1 6.8 1.7 8.8 3.7 2.5 1 1 1 2 2 2 0 BED zinc finger zf-LYAR PF08790.11 EGE06544.1 - 7.8 6.5 9.0 30 4.6 0.0 3.7 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 EGE06544.1 - 9.1 6.7 9.3 0.61 10.4 2.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF155 PF02582.14 EGE06545.1 - 3.5e-50 170.5 0.0 4.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 EGE06546.1 - 8.8e-19 67.8 0.0 3.7e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 EGE06546.1 - 0.018 15.0 0.3 0.018 15.0 0.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain WD40_like PF17005.5 EGE06546.1 - 0.049 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain Vps39_1 PF10366.9 EGE06546.1 - 0.14 12.5 0.1 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Cwf_Cwc_15 PF04889.12 EGE06546.1 - 4.2 7.0 12.9 9.2 5.9 12.9 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNHCP PF12647.7 EGE06547.1 - 0.011 15.7 0.1 0.015 15.3 0.1 1.1 1 0 0 1 1 1 0 RNHCP domain ATP-grasp_3 PF02655.14 EGE06548.1 - 2.2e-10 40.8 0.0 3.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain MARVEL PF01284.23 EGE06549.1 - 2.3e-06 27.7 3.6 3.7e-06 27.0 3.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3245 PF11595.8 EGE06549.1 - 0.17 12.3 1.3 2.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) RRM_1 PF00076.22 EGE06551.1 - 9.9e-19 66.9 0.3 1.5e-10 40.7 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE06551.1 - 0.0036 17.4 0.0 0.12 12.5 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif Vac7 PF12751.7 EGE06551.1 - 0.5 9.8 2.4 0.68 9.3 2.4 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 FRG2 PF15315.6 EGE06551.1 - 3.2 7.9 10.9 5.2 7.2 10.9 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 ArfGap PF01412.18 EGE06552.1 - 6.4e-31 106.8 0.0 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 EGE06553.1 - 1.8e-55 187.5 0.0 3.4e-55 186.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EGE06553.1 - 6.3e-25 87.1 0.0 1.5e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGE06553.1 - 1.3e-16 60.4 0.0 1e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGE06553.1 - 4.6e-06 26.9 0.0 1.3e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGE06553.1 - 6.3e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EGE06553.1 - 0.0022 17.8 0.1 0.56 10.0 0.0 2.6 1 1 1 2 2 2 2 Elongation factor G, domain IV Vps5 PF09325.10 EGE06554.1 - 3.2e-11 43.2 2.3 6.5e-11 42.2 2.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGE06554.1 - 1.2e-08 35.0 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PX domain GFA PF04828.14 EGE06555.1 - 6.5e-18 64.9 0.0 1e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APH PF01636.23 EGE06556.1 - 8e-09 35.8 0.1 1.2e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE06556.1 - 0.00087 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EGE06556.1 - 0.12 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase THOC2_N PF16134.5 EGE06557.1 - 6.7e-242 804.6 0.2 2.5e-241 802.8 0.0 1.9 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EGE06557.1 - 1.6e-107 359.2 0.0 2.3e-107 358.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EGE06557.1 - 2.7e-29 101.1 0.4 7e-29 99.7 0.0 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Menin PF05053.13 EGE06557.1 - 2.6 6.3 9.9 3.7 5.8 8.6 1.9 2 0 0 2 2 2 0 Menin Methyltransf_8 PF05148.15 EGE06558.1 - 0.26 11.1 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase SSP160 PF06933.11 EGE06558.1 - 5.5 5.1 19.5 8 4.5 19.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.16 EGE06559.1 - 2.5e-34 118.8 29.2 3.9e-34 118.1 29.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3188 PF11384.8 EGE06559.1 - 0.87 9.3 5.4 0.6 9.9 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Gly_transf_sug PF04488.15 EGE06560.1 - 7.3e-18 65.0 0.1 2.1e-17 63.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EGE06560.1 - 0.0072 15.7 0.1 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein zf-C2H2_7 PF15269.6 EGE06560.1 - 0.23 11.6 0.4 0.69 10.0 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger Abhydrolase_1 PF00561.20 EGE06562.1 - 1.8e-44 152.4 0.1 2.1e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE06562.1 - 0.017 15.8 8.9 0.029 15.0 8.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family HNH_2 PF13391.6 EGE06563.1 - 6.9e-05 22.9 0.0 0.00024 21.2 0.0 2.0 1 1 0 1 1 1 1 HNH endonuclease JIP_LZII PF16471.5 EGE06563.1 - 0.053 13.7 0.7 1.1 9.5 0.2 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II MIOX PF05153.15 EGE06565.1 - 1.4e-125 417.9 2.0 1.8e-125 417.5 2.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase DUF1796 PF08795.10 EGE06565.1 - 0.015 15.3 0.5 0.025 14.5 0.5 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) NOG1_N PF17835.1 EGE06565.1 - 0.037 14.0 3.2 0.2 11.6 0.1 2.7 2 1 0 2 2 2 0 NOG1 N-terminal helical domain HD PF01966.22 EGE06565.1 - 0.074 13.3 0.8 0.98 9.6 0.0 2.6 3 0 0 3 3 3 0 HD domain UBD PF16455.5 EGE06565.1 - 0.092 13.0 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding domain Cep57_CLD_2 PF14197.6 EGE06565.1 - 0.21 11.7 2.7 1.9 8.7 0.4 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Exo_endo_phos PF03372.23 EGE06566.1 - 0.0002 21.0 0.0 0.00058 19.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2786 PF10979.8 EGE06567.1 - 1.5e-15 56.8 0.7 1.5e-15 56.8 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) Atrophin-1 PF03154.15 EGE06567.1 - 0.13 10.6 5.7 0.23 9.7 5.7 1.3 1 0 0 1 1 1 0 Atrophin-1 family CENP-Q PF13094.6 EGE06567.1 - 4.4 7.5 11.2 0.042 14.1 2.8 1.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RTC PF01137.21 EGE06568.1 - 6.5e-44 149.8 0.0 8.1e-43 146.2 0.0 2.1 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Urocanase_C PF17392.2 EGE06568.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Urocanase C-terminal domain TSC21 PF15217.6 EGE06569.1 - 0.1 12.6 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 TSC21 family BAR PF03114.18 EGE06570.1 - 2.9e-13 50.0 0.3 4.2e-13 49.5 0.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGE06570.1 - 1.9e-12 46.6 0.1 3.8e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGE06570.1 - 4.6e-12 45.6 0.1 9.6e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGE06570.1 - 4.4e-09 35.9 0.1 9.7e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PIN_8 PF18476.1 EGE06570.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.8 3 0 0 3 3 3 0 PIN like domain U1snRNP70_N PF12220.8 EGE06570.1 - 3.5 8.3 9.3 4.9 7.9 1.2 2.8 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2439 PF10382.9 EGE06572.1 - 5.5e-24 84.3 0.0 9.7e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF4023 PF13215.6 EGE06572.1 - 0.15 12.1 0.3 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Methyltransf_23 PF13489.6 EGE06573.1 - 2.2e-15 56.9 0.0 3.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06573.1 - 2e-06 28.5 0.0 1.4e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06573.1 - 2.4e-06 28.1 0.0 1.1e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06573.1 - 8.9e-06 25.6 0.0 9.4e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE06573.1 - 0.0011 19.7 0.0 0.011 16.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Mcp5_PH PF12814.7 EGE06574.1 - 5.2e-44 149.3 0.2 1.1e-43 148.3 0.2 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EGE06574.1 - 9.8e-05 22.8 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Herpes_UL25 PF01499.16 EGE06574.1 - 7.1 5.0 17.6 0.1 11.1 4.9 3.0 2 1 1 3 3 3 0 Herpesvirus UL25 family zf-CCCH PF00642.24 EGE06575.1 - 3.8e-08 33.0 2.9 6.8e-08 32.2 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EGE06575.1 - 1.4e-07 31.3 7.0 3e-07 30.2 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE06575.1 - 4.6e-06 26.6 7.5 1.2e-05 25.3 7.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGE06575.1 - 5.9e-06 26.1 10.4 9.9e-06 25.4 10.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGE06575.1 - 6.4e-06 25.9 11.1 1.1e-05 25.1 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE06575.1 - 1.5e-05 24.7 12.2 2.7e-05 23.9 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE06575.1 - 1.6e-05 25.1 9.9 3.1e-05 24.2 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EGE06575.1 - 7.6e-05 22.6 6.1 0.00014 21.8 6.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EGE06575.1 - 0.0001 22.4 4.7 0.00025 21.1 4.7 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 EGE06575.1 - 0.0024 17.6 3.0 0.0041 16.9 3.0 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EGE06575.1 - 0.041 14.0 8.7 0.091 12.9 8.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cript PF10235.9 EGE06575.1 - 0.053 14.1 0.8 0.24 12.0 0.8 2.1 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Prok-RING_4 PF14447.6 EGE06575.1 - 0.14 12.1 9.2 0.25 11.2 9.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGE06575.1 - 0.56 10.5 6.2 1.4 9.3 6.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF5427 PF10310.9 EGE06575.1 - 1.1 8.1 9.7 1.4 7.8 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) zf-CCCH_2 PF14608.6 EGE06575.1 - 4.3 8.0 7.2 0.42 11.2 2.6 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF3431 PF11913.8 EGE06577.1 - 7.5e-83 277.5 0.1 9.4e-83 277.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Myb_DNA-bind_6 PF13921.6 EGE06579.1 - 0.00093 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE06579.1 - 0.042 14.0 0.5 0.12 12.6 0.5 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase PF00069.25 EGE06580.1 - 6.1e-57 193.0 0.1 7.3e-53 179.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06580.1 - 8.2e-27 94.1 0.1 2.7e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EGE06580.1 - 1.2e-10 41.5 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EGE06580.1 - 2.6e-06 26.5 0.1 1e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGE06580.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGE06580.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EGE06580.1 - 0.011 16.1 0.0 0.039 14.3 0.0 2.0 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGE06580.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bVLRF1 PF18826.1 EGE06582.1 - 4.9e-61 205.0 0.4 1.1e-60 203.8 0.4 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EGE06582.1 - 0.0001 22.5 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGE06582.1 - 0.00089 19.6 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGE06582.1 - 0.0021 18.4 0.0 0.0055 17.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGE06582.1 - 0.0062 17.1 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.7 EGE06582.1 - 0.079 13.3 0.2 0.17 12.2 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ABC_membrane PF00664.23 EGE06583.1 - 4.9e-87 292.1 31.1 2.3e-46 158.7 12.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE06583.1 - 7.5e-52 175.5 0.0 1.9e-30 106.2 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE06583.1 - 4.3e-10 39.4 0.9 0.00021 20.8 0.1 4.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGE06583.1 - 3e-06 27.2 1.1 0.0014 18.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGE06583.1 - 4.1e-06 26.9 1.9 0.036 14.1 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE06583.1 - 2.6e-05 24.7 0.8 0.027 14.8 0.7 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EGE06583.1 - 0.0022 18.1 0.7 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 EGE06583.1 - 0.0036 17.0 0.7 1.8 8.4 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGE06583.1 - 0.0051 16.6 0.3 3.4 7.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGE06583.1 - 0.0052 17.3 0.5 0.41 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 EGE06583.1 - 0.012 15.8 3.4 17 5.7 0.0 4.3 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGE06583.1 - 0.013 15.6 2.4 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGE06583.1 - 0.018 15.4 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 EGE06583.1 - 0.031 14.1 0.7 0.64 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGE06583.1 - 0.032 14.5 3.3 3.7 7.8 0.1 3.2 2 1 0 2 2 2 0 AAA domain DUP PF00674.18 EGE06583.1 - 0.048 13.8 0.7 0.36 11.0 0.7 2.6 1 0 0 1 1 1 0 DUP family DUF720 PF05302.11 EGE06583.1 - 0.093 12.6 0.1 0.3 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF720) IstB_IS21 PF01695.17 EGE06583.1 - 0.31 10.7 2.6 15 5.3 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein NACHT PF05729.12 EGE06583.1 - 0.46 10.4 5.0 6.4 6.7 0.1 3.2 3 0 0 3 3 3 0 NACHT domain PCM1_C PF15717.5 EGE06586.1 - 0.01 14.6 13.6 0.013 14.3 13.6 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus BAF1_ABF1 PF04684.13 EGE06586.1 - 0.027 13.6 13.4 0.031 13.4 13.4 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAP1 PF08601.10 EGE06586.1 - 0.15 11.7 10.7 0.18 11.5 10.7 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 LYRIC PF15686.5 EGE06586.1 - 0.26 10.8 25.4 0.34 10.4 25.4 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF2151 PF10221.9 EGE06586.1 - 0.53 8.8 10.6 0.66 8.5 10.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator FAM60A PF15396.6 EGE06586.1 - 1.2 9.1 16.4 1.5 8.8 16.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GREB1 PF15782.5 EGE06586.1 - 2.2 5.3 11.2 2.5 5.1 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_11 PF13086.6 EGE06586.1 - 3.5 7.3 14.3 4.8 6.9 14.3 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EGE06586.1 - 3.8 6.2 17.9 4.3 6.0 17.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 EGE06586.1 - 3.8 6.2 14.0 4.5 6.0 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Conotoxin PF02950.17 EGE06586.1 - 4.3 8.4 11.9 3.4 8.8 3.3 2.2 2 0 0 2 2 2 0 Conotoxin DUF2828 PF11443.8 EGE06586.1 - 5.1 5.1 17.1 6.5 4.7 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SRP-alpha_N PF04086.13 EGE06586.1 - 6.3 6.6 22.9 8.2 6.3 22.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hydin_ADK PF17213.3 EGE06586.1 - 6.8 6.9 12.1 9.6 6.4 12.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Raftlin PF15250.6 EGE06586.1 - 7.4 5.2 13.3 8.7 5.0 13.3 1.0 1 0 0 1 1 1 0 Raftlin DUF4710 PF15828.5 EGE06586.1 - 8.2 6.6 24.0 4.8 7.4 10.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) YhzD PF14120.6 EGE06586.1 - 9.2 6.5 8.1 1.1 9.4 3.9 1.7 1 1 1 2 2 2 0 YhzD-like protein Ferlin_C PF16165.5 EGE06586.1 - 9.7 6.1 24.1 16 5.4 22.8 1.8 1 1 1 2 2 2 0 Ferlin C-terminus TMEM208_SND2 PF05620.11 EGE06587.1 - 0.016 15.0 0.3 7.9 6.2 1.7 2.1 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF2841 PF11001.8 EGE06588.1 - 9.2e-53 177.5 0.1 1.6e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) CorA PF01544.18 EGE06588.1 - 0.2 10.9 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Zip PF02535.22 EGE06589.1 - 4.3e-52 177.4 3.9 5.3e-52 177.1 3.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 7TM_transglut PF14402.6 EGE06589.1 - 0.0054 16.2 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 7 transmembrane helices usually fused to an inactive transglutaminase Ni_hydr_CYTB PF01292.20 EGE06589.1 - 3.7 7.1 12.5 0.042 13.5 3.1 2.3 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 CPP1-like PF11833.8 EGE06589.1 - 9 5.9 6.0 16 5.1 0.2 3.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SAC3_GANP PF03399.16 EGE06590.1 - 4.1e-105 351.4 4.7 4.1e-105 351.4 4.7 2.2 2 1 1 3 3 3 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGE06590.1 - 4.7e-05 23.4 0.5 0.00016 21.6 0.5 1.9 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HC2 PF07382.11 EGE06590.1 - 0.42 10.7 20.8 0.82 9.7 20.8 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CN_hydrolase PF00795.22 EGE06592.1 - 2.1e-12 46.9 0.0 6.3e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CDC50 PF03381.15 EGE06595.1 - 3.7e-43 148.0 0.0 3.9e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family TPR_12 PF13424.6 EGE06596.1 - 1.8e-07 31.4 4.7 0.026 14.8 0.8 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE06596.1 - 0.00073 20.2 5.8 1.6 9.7 0.3 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE06596.1 - 0.0041 17.1 0.6 0.67 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE06596.1 - 0.0089 15.8 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE06596.1 - 0.034 14.4 0.1 4 7.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 EGE06597.1 - 1.4e-26 93.8 0.0 4.4e-26 92.2 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE06597.1 - 7.5e-15 54.9 0.1 2.6e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGE06597.1 - 6.8e-09 35.8 0.0 5.8e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE06597.1 - 5.2e-08 32.5 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE06597.1 - 1e-07 31.1 0.1 0.0011 17.8 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EGE06597.1 - 8.8e-06 25.0 0.5 5.8e-05 22.3 1.5 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EGE06597.1 - 0.00012 21.6 1.7 0.00035 20.0 1.6 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGE06597.1 - 0.00052 20.0 0.4 0.05 13.6 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGE06597.1 - 0.00056 19.3 1.1 0.0011 18.3 0.7 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EGE06597.1 - 0.0012 17.5 0.1 0.028 12.9 0.0 2.2 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.17 EGE06597.1 - 0.0013 18.0 0.5 0.0023 17.2 0.3 1.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGE06597.1 - 0.0033 16.7 0.1 0.0063 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EGE06597.1 - 0.011 16.3 2.3 0.22 12.1 1.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGE06597.1 - 0.032 14.7 0.0 0.07 13.6 0.0 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EGE06597.1 - 0.081 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EGE06597.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EGE06597.1 - 0.16 11.0 2.1 0.35 9.9 0.9 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGE06597.1 - 0.2 10.7 2.3 0.19 10.7 0.4 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein adh_short PF00106.25 EGE06597.1 - 0.35 10.3 1.1 0.65 9.4 1.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RPE65 PF03055.15 EGE06598.1 - 2.4e-116 389.7 0.0 2.8e-116 389.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SQS_PSY PF00494.19 EGE06599.1 - 4.7e-59 200.0 0.0 5.8e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase polyprenyl_synt PF00348.17 EGE06600.1 - 1e-67 227.9 0.0 1.5e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.10 EGE06601.1 - 2.8e-25 88.5 8.5 1e-24 86.6 5.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGE06601.1 - 2.2e-10 40.7 0.4 2.2e-10 40.7 0.4 2.2 2 0 0 2 2 2 1 Smr domain Connexin43 PF03508.13 EGE06601.1 - 0.62 9.7 3.3 0.45 10.1 0.8 1.9 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) DUF4407 PF14362.6 EGE06601.1 - 1.1 8.5 3.6 1.5 8.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pyrid_oxidase_2 PF13883.6 EGE06603.1 - 6.1e-36 123.9 0.0 1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EGE06603.1 - 0.06 13.5 0.0 0.33 11.2 0.0 2.0 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase F-box PF00646.33 EGE06604.1 - 0.00067 19.5 0.1 0.0065 16.3 0.1 2.4 2 0 0 2 2 2 1 F-box domain Ipi1_N PF12333.8 EGE06605.1 - 1.5e-27 96.1 0.1 1.5e-27 96.1 0.1 2.6 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 EGE06606.1 - 4.3e-05 23.2 0.1 0.38 10.5 0.0 3.2 3 0 0 3 3 3 3 Roadblock/LC7 domain YtxH PF12732.7 EGE06607.1 - 0.022 15.3 2.2 0.028 15.0 2.2 1.2 1 0 0 1 1 1 0 YtxH-like protein DUF883 PF05957.13 EGE06607.1 - 0.023 15.3 0.1 0.026 15.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.8 EGE06607.1 - 0.044 13.0 1.0 0.049 12.9 1.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein WXG100 PF06013.12 EGE06607.1 - 0.056 13.7 1.5 0.067 13.4 1.5 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG HOIP-UBA PF16678.5 EGE06607.1 - 0.068 13.2 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair NTF2 PF02136.20 EGE06607.1 - 0.069 13.7 0.3 0.074 13.6 0.3 1.0 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF4888 PF16229.5 EGE06607.1 - 0.092 12.7 0.3 0.1 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) DUF4527 PF15030.6 EGE06607.1 - 0.11 11.9 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) HSP9_HSP12 PF04119.12 EGE06607.1 - 0.21 12.0 4.7 0.43 11.0 4.8 1.6 1 1 1 2 2 2 0 Heat shock protein 9/12 CsbD PF05532.12 EGE06607.1 - 1.8 8.5 11.0 19 5.2 11.0 2.3 1 1 0 1 1 1 0 CsbD-like Crystall PF00030.19 EGE06608.1 - 0.0047 17.1 0.0 0.0063 16.7 0.0 1.2 1 0 0 1 1 1 1 Beta/Gamma crystallin Aa_trans PF01490.18 EGE06609.1 - 6.2e-39 133.9 38.8 7.4e-39 133.6 38.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Tubulin PF00091.25 EGE06610.1 - 2.7e-70 236.6 0.0 4.2e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGE06610.1 - 8.2e-43 145.6 0.6 1.7e-42 144.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGE06610.1 - 1.1e-07 32.1 0.0 2.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGE06610.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Hrs_helical PF12210.8 EGE06610.1 - 0.13 12.8 0.4 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Tubulin_2 PF13809.6 EGE06610.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DEAD_2 PF06733.15 EGE06610.1 - 0.2 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 YcaO PF02624.16 EGE06611.1 - 0.039 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Aldo_ket_red PF00248.21 EGE06612.1 - 2.6e-53 181.2 0.0 2.9e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 EGE06613.1 - 1.3e-09 38.3 28.5 1.5e-05 25.2 1.2 2.8 3 0 0 3 3 3 2 EamA-like transporter family Actin PF00022.19 EGE06614.1 - 5.4e-112 374.4 0.0 3.8e-111 371.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGE06614.1 - 0.068 12.0 0.0 0.43 9.4 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.8 EGE06615.1 - 4.8e-23 81.5 1.4 8.1e-23 80.7 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) G_path_suppress PF15991.5 EGE06615.1 - 0.042 14.0 8.3 0.072 13.2 8.3 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor BMFP PF04380.13 EGE06615.1 - 0.047 14.2 0.6 0.1 13.1 0.6 1.6 1 0 0 1 1 1 0 Membrane fusogenic activity bZIP_1 PF00170.21 EGE06615.1 - 0.11 12.6 11.1 0.083 13.0 8.5 2.0 1 1 1 2 2 2 0 bZIP transcription factor Fungal_trans PF04082.18 EGE06616.1 - 3.6e-10 39.3 0.0 9.7e-10 37.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06616.1 - 1.7e-07 31.3 6.9 1.7e-07 31.3 6.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 EGE06617.1 - 5.8e-15 55.5 0.0 8.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06617.1 - 5.1e-12 46.3 0.0 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE06617.1 - 1.2e-11 45.1 0.0 2.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06617.1 - 7e-11 42.1 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE06617.1 - 1e-10 42.2 0.0 1.7e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE06617.1 - 0.0013 18.1 0.0 0.0074 15.7 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EGE06617.1 - 0.0027 16.8 0.0 0.016 14.3 0.0 2.0 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EGE06617.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_19 PF04672.12 EGE06617.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl methyltransferase TehB PF03848.14 EGE06617.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Tellurite resistance protein TehB Fungal_trans PF04082.18 EGE06618.1 - 8.8e-09 34.8 0.0 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Coatomer_E PF04733.14 EGE06619.1 - 4.9e-65 219.8 6.6 5.6e-65 219.6 6.6 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGE06619.1 - 5e-08 33.3 22.0 0.00056 20.4 3.5 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE06619.1 - 1.6e-07 31.4 5.5 0.019 15.2 1.1 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGE06619.1 - 5.6e-06 26.9 22.8 0.0027 18.3 0.2 4.9 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE06619.1 - 0.00016 22.2 21.4 0.0092 16.7 0.1 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE06619.1 - 0.00024 21.3 14.0 0.095 13.0 2.5 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGE06619.1 - 0.0072 16.9 4.3 0.23 12.2 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat Peptidase_S11 PF00768.20 EGE06619.1 - 0.008 15.6 0.2 0.01 15.3 0.2 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase TPR_2 PF07719.17 EGE06619.1 - 0.052 13.7 0.0 0.052 13.7 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGE06619.1 - 0.095 12.6 5.4 0.48 10.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TF_AP-2 PF03299.14 EGE06619.1 - 0.1 12.6 0.5 0.15 12.0 0.5 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 TetR_C_25 PF17933.1 EGE06619.1 - 0.11 12.8 0.6 0.29 11.5 0.6 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_9 PF13371.6 EGE06619.1 - 0.12 12.5 5.8 0.18 12.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE06619.1 - 0.21 12.3 21.4 0.26 12.0 0.7 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 EGE06619.1 - 0.43 10.7 7.2 1.3 9.1 3.1 3.0 1 1 1 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.6 EGE06619.1 - 2.2 8.3 8.1 13 5.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 EGE06620.1 - 4e-25 88.9 0.0 9.6e-25 87.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGE06620.1 - 1.2e-23 83.6 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGE06620.1 - 0.0074 15.8 0.0 0.36 10.3 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF2974 PF11187.8 EGE06620.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 EGE06620.1 - 0.071 12.9 0.0 2.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PMI_typeI PF01238.21 EGE06621.1 - 4.5e-93 312.4 0.0 4.9e-66 223.4 0.0 2.1 1 1 1 2 2 2 2 Phosphomannose isomerase type I AraC_binding PF02311.19 EGE06621.1 - 0.016 15.1 0.0 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain DUF1325 PF07039.11 EGE06622.1 - 5.2e-34 117.2 0.0 1.2e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EGE06622.1 - 0.0044 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain MS_channel PF00924.18 EGE06622.1 - 0.24 10.9 0.1 0.37 10.3 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel NOA36 PF06524.12 EGE06622.1 - 6.6 6.0 15.6 15 4.8 15.6 1.6 1 0 0 1 1 1 0 NOA36 protein GTP_cyclohydro2 PF00925.20 EGE06623.1 - 3e-57 192.7 0.0 4.1e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II APH PF01636.23 EGE06624.1 - 5e-09 36.4 0.0 6.5e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGE06625.1 - 2e-13 50.3 0.0 5.1e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06625.1 - 1.4e-08 34.4 0.0 2.9e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGE06625.1 - 0.00065 19.3 0.0 0.0016 18.1 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGE06625.1 - 0.003 17.5 0.1 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family SpoVAD PF07451.11 EGE06625.1 - 0.31 9.7 0.2 0.78 8.4 0.1 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) MADF_DNA_bdg PF10545.9 EGE06626.1 - 0.057 13.7 0.1 0.082 13.2 0.1 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TIP_N PF12457.8 EGE06627.1 - 0.0018 18.6 0.4 0.0033 17.8 0.4 1.3 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal DUF4611 PF15387.6 EGE06627.1 - 0.0078 16.4 1.4 0.012 15.8 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) FAM176 PF14851.6 EGE06627.1 - 0.16 11.6 2.5 0.2 11.3 2.5 1.1 1 0 0 1 1 1 0 FAM176 family DUF4632 PF15451.6 EGE06627.1 - 0.28 11.3 4.1 0.44 10.6 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) NOA36 PF06524.12 EGE06627.1 - 0.92 8.8 3.0 1.2 8.4 3.0 1.1 1 0 0 1 1 1 0 NOA36 protein PAC1 PF16094.5 EGE06627.1 - 1.5 8.0 4.2 1.8 7.6 4.2 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AA_permease PF00324.21 EGE06628.1 - 3.4e-62 210.6 16.6 3.8e-62 210.4 16.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE06628.1 - 8.6e-19 67.7 15.4 1e-18 67.4 15.4 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.6 EGE06628.1 - 0.018 15.0 0.4 0.041 13.8 0.4 1.5 1 0 0 1 1 1 0 TMEM213 family DUF2207 PF09972.9 EGE06628.1 - 2.2 6.9 4.1 6.2 5.5 1.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) F-box-like PF12937.7 EGE06629.1 - 9.3e-05 22.2 2.0 0.00021 21.1 0.5 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGE06629.1 - 0.00047 20.0 0.1 0.0026 17.6 0.1 2.4 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EGE06629.1 - 0.17 11.7 1.3 3.1 7.6 0.1 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 EGE06629.1 - 9.9 6.5 6.1 3 8.1 0.0 3.3 4 1 0 4 4 4 0 Leucine Rich repeat FTA4 PF13093.6 EGE06631.1 - 3.3e-61 206.7 0.1 4e-61 206.4 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF148 PF02520.17 EGE06631.1 - 0.0027 17.8 0.2 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF148 SlyX PF04102.12 EGE06632.1 - 0.024 15.3 0.8 0.16 12.6 0.3 2.4 2 0 0 2 2 2 0 SlyX SIKE PF05769.11 EGE06632.1 - 0.051 13.5 5.7 0.07 13.1 5.7 1.2 1 0 0 1 1 1 0 SIKE family RAP1 PF07218.11 EGE06632.1 - 4.3 5.5 7.3 5.8 5.1 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HAD_2 PF13419.6 EGE06633.1 - 1.8e-06 28.2 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE06633.1 - 0.0033 17.8 0.0 0.0044 17.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE06633.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L5e PF17144.4 EGE06634.1 - 5.1e-67 224.9 0.0 8.3e-67 224.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGE06634.1 - 5.2e-34 117.1 2.8 5.2e-34 117.1 2.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3135 PF11333.8 EGE06635.1 - 0.0016 18.6 0.2 0.087 13.1 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) LRR_6 PF13516.6 EGE06635.1 - 0.0037 17.2 2.5 6.1 7.2 0.0 5.2 6 0 0 6 6 6 1 Leucine Rich repeat ABC_membrane_2 PF06472.15 EGE06636.1 - 3.3e-49 167.7 1.4 8e-29 100.9 0.1 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGE06636.1 - 1.9e-18 67.3 0.0 3.5e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGE06636.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGE06636.1 - 0.0037 17.8 0.1 0.011 16.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGE06636.1 - 0.0064 16.2 0.0 0.033 13.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGE06636.1 - 0.032 13.7 0.0 0.086 12.3 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGE06636.1 - 0.041 14.3 0.2 0.39 11.1 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Glyco_transf_22 PF03901.17 EGE06636.1 - 0.064 12.5 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Rad17 PF03215.15 EGE06636.1 - 0.086 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGE06636.1 - 0.15 12.4 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 EGE06636.1 - 0.16 11.6 0.1 0.38 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.22 EGE06637.1 - 1.8e-62 211.6 0.0 2.3e-62 211.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phosphorylase PF00343.20 EGE06640.1 - 0 1058.2 0.0 0 1058.0 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase MFS_1 PF07690.16 EGE06641.1 - 4.8e-12 45.5 11.7 6.7e-12 45.0 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06641.1 - 0.022 13.6 4.3 0.032 13.1 4.3 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter PPV_E1_C PF00519.17 EGE06641.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase ketoacyl-synt PF00109.26 EGE06642.1 - 8.9e-60 202.4 3.9 3.8e-57 193.8 3.9 2.7 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGE06642.1 - 1.4e-59 202.2 0.0 2.7e-59 201.3 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGE06642.1 - 4.3e-46 157.1 0.0 1.6e-45 155.3 0.0 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EGE06642.1 - 9.2e-43 145.0 0.6 2.3e-42 143.8 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGE06642.1 - 1.1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EGE06642.1 - 4.3e-13 49.4 0.1 6.7e-12 45.6 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.6 EGE06642.1 - 2.1e-11 43.6 0.0 4.2e-11 42.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGE06642.1 - 1.5e-05 24.5 1.7 6.2e-05 22.5 0.8 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.25 EGE06642.1 - 0.0098 15.4 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KfrA_N PF11740.8 EGE06642.1 - 0.071 13.8 0.2 0.29 11.8 0.0 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fungal_trans PF04082.18 EGE06644.1 - 4.4e-08 32.5 0.3 1.1e-07 31.2 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF629 PF04780.12 EGE06644.1 - 0.032 12.8 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) adh_short_C2 PF13561.6 EGE06645.1 - 6.8e-62 209.1 2.5 2.1e-61 207.5 2.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE06645.1 - 2.1e-43 148.1 1.2 3.6e-43 147.3 1.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE06645.1 - 5.3e-10 39.5 0.3 5.3e-10 39.5 0.3 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 EGE06646.1 - 2.9e-20 72.5 0.1 1.7e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGE06646.1 - 2.6e-08 33.7 0.0 5.7e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE06646.1 - 5e-07 29.8 0.1 1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 KR domain p450 PF00067.22 EGE06647.1 - 4.9e-76 256.3 0.0 6e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.12 EGE06648.1 - 1.7e-32 112.6 0.0 5.3e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EGE06648.1 - 2.3e-24 85.8 0.0 6e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EGE06648.1 - 4.3e-11 42.7 0.0 7.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGE06648.1 - 5.4e-10 39.5 0.0 1.4e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EGE06648.1 - 0.092 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 EGE06649.1 - 1.9e-11 44.4 0.0 4.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EGE06649.1 - 1.2e-07 31.6 0.1 2.3e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TFIIF_beta_N PF17683.1 EGE06650.1 - 9.5e-32 110.5 0.9 1.7e-31 109.7 0.9 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EGE06650.1 - 3.9e-28 97.4 0.3 7.3e-28 96.5 0.3 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EGE06650.1 - 0.015 16.1 6.5 0.09 13.6 6.5 2.1 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain zf-CCCH PF00642.24 EGE06651.1 - 4.7e-13 48.7 26.2 0.00056 19.8 1.3 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE06651.1 - 5.5e-08 32.6 28.3 0.0064 16.5 0.5 5.9 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 EGE06651.1 - 0.0018 18.5 14.1 0.022 15.0 1.1 3.7 1 1 2 3 3 3 2 Zinc-finger containing family Torus PF16131.5 EGE06651.1 - 0.01 16.5 25.3 0.31 11.8 1.0 4.9 2 1 3 5 5 5 0 Torus domain zf-C3H1 PF10650.9 EGE06651.1 - 1.2 8.9 0.0 1.2 8.9 0.0 4.0 5 0 0 5 5 5 0 Putative zinc-finger domain FXMRP1_C_core PF12235.8 EGE06651.1 - 6.2 7.5 15.4 15 6.2 13.5 2.4 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal bZIP_Maf PF03131.17 EGE06654.1 - 1.4e-05 25.5 15.3 1.4e-05 25.5 15.3 2.9 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EGE06654.1 - 0.00021 21.3 11.6 0.00021 21.3 11.6 3.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EGE06654.1 - 0.00026 21.0 14.2 0.00026 21.0 14.2 3.3 1 1 2 3 3 3 1 bZIP transcription factor DUF1062 PF06353.12 EGE06654.1 - 0.17 12.7 9.3 1.1 10.1 7.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1062) AAA_23 PF13476.6 EGE06654.1 - 3.2 8.2 11.7 6.3 7.3 11.7 1.5 1 0 0 1 1 1 0 AAA domain RNA_pol_I_TF PF04090.12 EGE06655.1 - 2e-06 27.5 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor OmpH PF03938.14 EGE06655.1 - 4.8 7.5 8.4 2.3 8.5 0.3 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) ECM11 PF15463.6 EGE06656.1 - 5e-40 137.2 0.0 1.3e-39 135.9 0.0 1.7 1 0 0 1 1 1 1 Extracellular mutant protein 11 FAM216B PF15107.6 EGE06656.1 - 0.038 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 FAM216B protein family zf-RING_2 PF13639.6 EGE06657.1 - 1.4e-12 47.7 8.2 2.2e-12 47.1 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGE06657.1 - 3.7e-09 36.7 5.0 6.9e-09 35.9 5.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGE06657.1 - 2.5e-07 30.4 6.6 4e-07 29.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGE06657.1 - 2.5e-06 27.1 5.5 4.6e-06 26.3 5.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGE06657.1 - 6.9e-06 25.6 4.3 1.2e-05 24.9 4.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGE06657.1 - 1.3e-05 25.0 8.1 2e-05 24.4 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGE06657.1 - 0.00017 21.6 3.5 0.00045 20.2 3.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGE06657.1 - 0.00027 20.8 6.2 0.00041 20.3 6.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGE06657.1 - 0.00035 20.4 5.2 0.00059 19.6 5.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGE06657.1 - 0.0026 17.7 6.3 0.0055 16.7 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGE06657.1 - 0.0029 17.4 5.8 0.0046 16.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EGE06657.1 - 0.0071 16.4 1.6 0.014 15.4 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger YopE_N PF09020.10 EGE06657.1 - 0.0087 16.3 0.9 0.032 14.5 0.9 2.0 1 0 0 1 1 1 1 YopE, N terminal zf-Nse PF11789.8 EGE06657.1 - 0.065 13.1 3.3 0.12 12.2 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EGE06657.1 - 0.07 13.3 9.0 0.12 12.6 9.0 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EGE06657.1 - 0.12 12.6 5.7 0.22 11.7 5.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGE06657.1 - 0.28 11.5 1.9 0.53 10.6 1.9 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 EGE06657.1 - 3.6 7.6 7.9 2.4 8.2 6.0 1.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 AMP-binding PF00501.28 EGE06658.1 - 4.7e-72 242.9 0.0 6.8e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EGE06658.1 - 2e-15 56.9 0.1 5.2e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EGE06658.1 - 2.9e-14 52.1 1.8 2.6e-05 23.7 0.3 7.2 6 2 0 6 6 6 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGE06658.1 - 9.2e-06 25.3 21.2 0.015 15.0 0.1 5.9 5 1 1 6 6 6 4 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.16 EGE06659.1 - 1.5e-35 122.8 52.7 1.6e-34 119.4 50.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE06659.1 - 1.9e-23 82.8 21.5 6.7e-22 77.6 17.1 2.5 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE06659.1 - 3.7e-11 42.6 19.2 3.7e-11 42.6 19.2 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EGE06659.1 - 0.21 10.4 18.6 0.018 13.9 10.3 2.6 2 1 0 2 2 2 0 MFS_1 like family Fungal_trans_2 PF11951.8 EGE06660.1 - 2.8e-10 39.6 7.0 4.6e-10 38.9 3.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06660.1 - 7.3e-06 26.0 10.8 1.5e-05 25.0 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EGE06660.1 - 1.7 9.0 7.9 0.85 10.0 3.8 2.4 2 0 0 2 2 2 0 Opy2 protein NUDE_C PF04880.13 EGE06660.1 - 2 8.9 7.2 4.2 7.8 7.2 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3583 PF12126.8 EGE06660.1 - 4.8 6.6 6.6 8.1 5.8 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Helicase_C PF00271.31 EGE06661.1 - 1.3e-12 48.0 0.1 2.7e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGE06661.1 - 4e-11 43.5 0.1 1.1e-10 42.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.11 EGE06661.1 - 0.0006 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like zf-Di19 PF05605.12 EGE06662.1 - 0.037 14.3 0.6 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2284 PF10050.9 EGE06663.1 - 0.023 14.5 1.4 0.025 14.3 1.4 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) zf-C3HC4_2 PF13923.6 EGE06663.1 - 0.66 9.9 6.6 12 5.8 4.4 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase_fungal PF17667.1 EGE06667.1 - 9.7e-34 116.8 0.5 8.6e-18 64.3 0.2 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EGE06667.1 - 0.0039 16.6 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain YaaC PF14175.6 EGE06667.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 YaaC-like Protein Peroxin-3 PF04882.12 EGE06668.1 - 7.6e-10 38.4 0.0 7.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 APH PF01636.23 EGE06670.1 - 9.6e-06 25.7 0.0 2.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE06670.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Chromo PF00385.24 EGE06671.1 - 1.2e-07 31.5 0.5 3.1e-07 30.2 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HrcA PF01628.21 EGE06675.1 - 0.015 15.2 1.4 0.016 15.2 1.4 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain ADIP PF11559.8 EGE06675.1 - 0.015 15.4 7.2 0.2 11.7 7.2 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Retrotran_gag_2 PF14223.6 EGE06675.1 - 0.016 14.8 0.5 0.026 14.2 0.5 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1335 PF07056.11 EGE06675.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1335) Shigella_OspC PF06128.11 EGE06675.1 - 0.089 12.5 0.1 0.092 12.5 0.1 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein FKBP_C PF00254.28 EGE06678.1 - 8.7e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HNH_2 PF13391.6 EGE06680.1 - 2e-12 47.0 0.0 4.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Ran_BP1 PF00638.18 EGE06681.1 - 8.5e-15 55.1 0.1 1.8e-08 34.6 0.2 2.4 2 0 0 2 2 2 2 RanBP1 domain HSP70 PF00012.20 EGE06682.1 - 1.2e-05 23.7 0.0 0.00069 17.9 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein ADIP PF11559.8 EGE06683.1 - 0.045 13.8 3.0 0.1 12.7 3.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EGE06683.1 - 0.07 13.8 0.8 0.59 10.8 0.6 2.4 2 1 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 EGE06683.1 - 0.13 12.3 6.3 2.1 8.5 0.1 2.8 1 1 1 2 2 2 0 Basic region leucine zipper TolA_bind_tri PF16331.5 EGE06683.1 - 0.94 9.6 6.3 1.2 9.3 4.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation MMR_HSR1 PF01926.23 EGE06684.1 - 8.7e-09 35.5 2.4 7.8e-08 32.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGE06684.1 - 2.2e-07 30.4 1.0 3.8e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EGE06684.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.3 3 0 0 3 3 3 1 RsgA GTPase Septin PF00735.18 EGE06684.1 - 0.0015 17.9 0.0 0.0015 17.9 0.0 2.3 2 1 0 2 2 2 1 Septin FeoB_N PF02421.18 EGE06684.1 - 0.0022 17.5 0.0 0.0053 16.3 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B NB-ARC PF00931.22 EGE06684.1 - 0.0037 16.5 0.3 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 EGE06684.1 - 0.0094 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 EGE06684.1 - 0.019 15.0 16.1 0.038 14.0 0.0 4.0 2 2 1 3 3 2 0 Dynamin family SRPRB PF09439.10 EGE06684.1 - 0.02 14.4 0.1 0.02 14.4 0.1 2.5 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit IIGP PF05049.13 EGE06684.1 - 0.026 13.6 0.1 0.026 13.6 0.1 1.7 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EGE06684.1 - 0.046 14.0 0.1 0.046 14.0 0.1 2.4 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGE06684.1 - 0.081 13.4 0.0 0.081 13.4 0.0 2.7 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 EGE06684.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4407 PF14362.6 EGE06684.1 - 0.14 11.5 14.9 0.24 10.7 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_lysozyme PF00959.19 EGE06684.1 - 2.3 8.7 4.4 22 5.5 0.0 3.5 2 1 0 3 3 3 0 Phage lysozyme Fzo_mitofusin PF04799.13 EGE06684.1 - 2.3 7.7 15.2 0.15 11.6 2.5 2.7 2 1 1 3 3 3 0 fzo-like conserved region Exonuc_VII_L PF02601.15 EGE06684.1 - 7.7 6.0 15.4 12 5.4 15.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cu-oxidase_3 PF07732.15 EGE06685.1 - 2.4e-43 146.9 0.2 3e-42 143.4 0.9 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE06685.1 - 6.4e-41 139.3 3.5 1.3e-35 122.1 0.0 4.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE06685.1 - 8.8e-26 90.9 0.0 2.9e-25 89.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Yip1 PF04893.17 EGE06686.1 - 6.9e-13 48.7 15.7 1.3e-12 47.8 15.7 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EGE06686.1 - 0.0076 16.0 2.4 0.011 15.5 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) IBR PF01485.21 EGE06687.1 - 0.0083 16.3 6.4 0.0083 16.3 6.4 5.1 5 1 0 5 5 5 3 IBR domain, a half RING-finger domain DMA PF03474.14 EGE06687.1 - 0.024 14.2 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif adh_short PF00106.25 EGE06688.1 - 7.5e-83 276.8 5.6 1e-42 145.8 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGE06688.1 - 6.2e-66 222.3 3.2 5.9e-34 117.6 0.2 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EGE06688.1 - 8.2e-32 109.4 0.0 1.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EGE06688.1 - 2e-24 86.5 3.2 1.1e-11 45.0 0.3 2.6 2 1 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EGE06688.1 - 6.7e-05 22.3 0.6 0.0099 15.2 0.5 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EGE06688.1 - 1.2 9.0 5.4 14 5.5 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 EGE06688.1 - 3.6 7.6 5.4 20 5.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF543) MeaB PF03308.16 EGE06689.1 - 0.0012 17.9 0.1 0.36 9.8 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 EGE06689.1 - 0.021 14.1 0.0 0.025 13.8 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain TsaE PF02367.17 EGE06689.1 - 0.028 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PRK PF00485.18 EGE06689.1 - 0.098 12.4 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LysM PF01476.20 EGE06690.1 - 0.068 13.2 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 LysM domain Fungal_trans PF04082.18 EGE06691.1 - 3.1e-36 124.8 0.0 2.6e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06691.1 - 0.0032 17.6 1.0 0.0064 16.6 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP3D1 PF06375.11 EGE06692.1 - 0.0086 16.3 6.3 0.013 15.8 6.3 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 PPDFL PF15060.6 EGE06692.1 - 0.087 13.4 0.3 0.16 12.5 0.3 1.3 1 0 0 1 1 1 0 Differentiation and proliferation regulator DUF3464 PF11947.8 EGE06692.1 - 0.15 11.8 0.7 0.22 11.3 0.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 BRF1 PF07741.13 EGE06692.1 - 5.8 7.3 13.5 11 6.4 13.5 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Hce2 PF14856.6 EGE06693.1 - 7.1e-31 106.5 1.3 1.6e-30 105.4 1.3 1.7 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Glyco_hydro_18 PF00704.28 EGE06693.1 - 1.3e-21 77.6 0.2 9.6e-11 42.0 0.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EGE06693.1 - 0.0019 18.6 7.8 0.0019 18.6 7.8 2.3 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 EGE06693.1 - 0.11 12.6 1.3 0.29 11.2 0.1 2.3 2 0 0 2 2 2 0 LysM domain PigN PF04987.14 EGE06694.1 - 1.4e-162 541.7 28.4 1.4e-162 541.7 28.4 1.4 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGE06694.1 - 5.9e-10 39.3 3.9 2.5e-08 33.9 3.6 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGE06694.1 - 8.2e-09 35.3 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EGE06694.1 - 6.5e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily LolB PF03550.14 EGE06694.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Csm1 PF12539.8 EGE06695.1 - 6.9e-32 109.9 0.2 2.3e-31 108.2 0.1 1.9 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Atg14 PF10186.9 EGE06695.1 - 0.00014 21.1 9.5 0.00014 21.1 9.5 1.7 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EGE06695.1 - 0.001 17.1 7.3 0.001 17.1 7.3 1.5 2 0 0 2 2 1 1 V-type ATPase 116kDa subunit family PKcGMP_CC PF16808.5 EGE06695.1 - 0.0021 17.9 2.1 0.0021 17.9 2.1 2.3 2 0 0 2 2 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase MscS_porin PF12795.7 EGE06695.1 - 0.0022 17.6 17.7 0.0022 17.6 17.7 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain TolA_bind_tri PF16331.5 EGE06695.1 - 0.0031 17.5 9.5 0.0031 17.5 9.5 2.4 1 1 1 2 2 2 1 TolA binding protein trimerisation Filament PF00038.21 EGE06695.1 - 0.0053 16.4 11.3 0.01 15.5 11.3 1.5 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 EGE06695.1 - 0.0058 15.6 16.5 0.011 14.7 16.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 EGE06695.1 - 0.012 13.8 9.6 0.018 13.2 9.6 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Allexi_40kDa PF05549.11 EGE06695.1 - 0.022 14.3 6.5 0.06 12.8 6.5 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Prominin PF05478.11 EGE06695.1 - 0.042 11.8 8.4 0.063 11.2 8.4 1.1 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 EGE06695.1 - 0.099 12.7 22.5 0.41 10.7 22.5 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 EGE06695.1 - 0.1 13.0 14.6 0.28 11.6 14.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-O PF09496.10 EGE06695.1 - 0.14 12.1 3.7 0.38 10.7 3.7 1.7 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Macoilin PF09726.9 EGE06695.1 - 0.19 10.3 21.7 0.26 9.8 21.7 1.1 1 0 0 1 1 1 0 Macoilin family COG5 PF10392.9 EGE06695.1 - 0.26 11.5 8.7 0.55 10.4 8.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DHR10 PF18595.1 EGE06695.1 - 0.32 11.1 24.2 19 5.3 24.2 3.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 EGE06695.1 - 0.32 10.2 9.5 0.54 9.5 9.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EGE06695.1 - 0.33 10.2 13.9 0.69 9.2 13.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Erp_C PF06780.11 EGE06695.1 - 0.36 10.9 6.4 2.3 8.2 0.4 2.9 2 1 1 3 3 3 0 Erp protein C-terminus MCU PF04678.13 EGE06695.1 - 0.38 10.8 7.5 0.93 9.6 7.5 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc42p PF11544.8 EGE06695.1 - 0.43 10.6 11.7 0.076 13.0 4.8 3.0 1 1 1 2 2 2 0 Spindle pole body component Spc42p CREPT PF16566.5 EGE06695.1 - 0.54 10.4 11.8 0.95 9.6 11.1 1.7 2 0 0 2 2 1 0 Cell-cycle alteration and expression-elevated protein in tumour Exonuc_VII_L PF02601.15 EGE06695.1 - 0.65 9.5 13.2 0.038 13.6 8.1 1.5 2 0 0 2 2 1 0 Exonuclease VII, large subunit Med9 PF07544.13 EGE06695.1 - 0.67 10.1 15.6 2.8 8.1 12.1 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FliJ PF02050.16 EGE06695.1 - 0.82 9.9 16.0 1.7 8.9 16.0 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein Cep57_CLD PF14073.6 EGE06695.1 - 0.9 9.5 22.5 0.022 14.8 13.8 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF2203 PF09969.9 EGE06695.1 - 1.8 9.3 9.8 0.14 12.9 4.4 2.1 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) Nup88 PF10168.9 EGE06695.1 - 2 6.1 10.3 2.9 5.6 10.3 1.1 1 0 0 1 1 1 0 Nuclear pore component FUSC PF04632.12 EGE06695.1 - 2 6.8 4.1 2.9 6.3 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.16 EGE06695.1 - 2.1 8.5 17.4 2.1 8.5 11.9 2.9 1 1 1 2 2 2 0 Hr1 repeat COG6 PF06419.11 EGE06695.1 - 2.4 6.3 13.1 3.2 5.8 13.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Fib_alpha PF08702.10 EGE06695.1 - 2.4 8.4 13.6 9.1 6.5 13.3 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.8 EGE06695.1 - 2.5 6.6 6.0 3.9 6.0 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Baculo_PEP_C PF04513.12 EGE06695.1 - 3.9 7.5 11.0 2.6 8.1 8.5 1.9 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 EGE06695.1 - 3.9 7.2 12.4 9.4 6.0 12.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) USP8_interact PF08941.10 EGE06695.1 - 4.4 7.1 6.1 1.9 8.3 3.2 1.7 1 1 1 2 2 2 0 USP8 interacting IFT57 PF10498.9 EGE06695.1 - 5.3 5.9 20.3 0.042 12.8 9.6 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 EGE06695.1 - 5.6 7.0 8.0 16 5.5 7.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 EGE06695.1 - 6.6 6.7 11.9 15 5.5 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CorA PF01544.18 EGE06695.1 - 7.1 5.9 8.2 4.1 6.6 6.3 1.5 2 0 0 2 2 1 0 CorA-like Mg2+ transporter protein AAA PF00004.29 EGE06696.1 - 6.1e-37 127.0 0.0 1.6e-36 125.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE06696.1 - 1.6e-08 34.2 0.0 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EGE06696.1 - 1.6e-05 25.0 0.0 9.4e-05 22.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EGE06696.1 - 1.7e-05 24.9 0.3 0.00029 20.9 0.1 2.9 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGE06696.1 - 2e-05 25.1 0.6 0.00014 22.3 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EGE06696.1 - 2.2e-05 24.3 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGE06696.1 - 0.00018 21.7 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGE06696.1 - 0.00038 20.8 0.1 0.0062 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE06696.1 - 0.00051 20.6 0.1 0.003 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGE06696.1 - 0.00061 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGE06696.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGE06696.1 - 0.0011 18.4 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGE06696.1 - 0.0012 18.5 0.1 0.027 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGE06696.1 - 0.0015 18.9 0.0 0.0049 17.2 0.0 2.1 1 1 1 2 2 1 1 RNA helicase TniB PF05621.11 EGE06696.1 - 0.0028 17.1 0.0 2.9 7.3 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 EGE06696.1 - 0.0041 17.1 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Parvo_NS1 PF01057.17 EGE06696.1 - 0.0045 16.1 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EGE06696.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGE06696.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGE06696.1 - 0.0093 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGE06696.1 - 0.0098 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGE06696.1 - 0.011 15.6 0.1 0.038 13.9 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 EGE06696.1 - 0.028 14.9 0.2 0.088 13.3 0.0 2.0 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.13 EGE06696.1 - 0.043 13.0 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGE06696.1 - 0.047 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 EGE06696.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 EGE06696.1 - 0.063 13.1 1.0 0.35 10.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGE06696.1 - 0.063 13.2 0.0 0.24 11.3 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_6 PF12774.7 EGE06696.1 - 0.067 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EGE06696.1 - 0.072 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EGE06696.1 - 0.084 12.1 0.0 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EGE06696.1 - 0.13 11.6 0.0 0.57 9.5 0.0 1.9 1 1 1 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EGE06696.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cys_Met_Meta_PP PF01053.20 EGE06697.1 - 6.5e-141 469.3 0.0 7.6e-141 469.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGE06697.1 - 0.00023 20.6 0.0 0.00072 19.0 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGE06697.1 - 0.016 14.5 0.0 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 EGE06697.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus MFS_1 PF07690.16 EGE06698.1 - 1.2e-37 129.7 37.0 1.4e-25 90.0 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MTP18 PF10558.9 EGE06700.1 - 3.1e-40 137.9 0.0 4.8e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) QRPTase_C PF01729.19 EGE06700.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ATP19 PF11022.8 EGE06701.1 - 1.1e-25 89.8 0.1 1.3e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K AAT PF03417.16 EGE06702.1 - 2.2e-30 106.1 0.0 2.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ACPS PF01648.20 EGE06703.1 - 1.5e-14 54.1 0.0 1.9e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGE06703.1 - 0.085 13.0 4.3 0.71 10.0 2.6 2.6 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain APH PF01636.23 EGE06704.1 - 5.1e-13 49.5 0.0 1.2e-12 48.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE06704.1 - 0.036 13.4 0.0 1.4 8.2 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGE06704.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EGE06704.1 - 0.067 12.5 0.1 0.32 10.3 0.0 2.0 2 1 0 2 2 2 0 Ecdysteroid kinase DUF1679 PF07914.11 EGE06704.1 - 0.078 11.8 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Rib PF08428.10 EGE06705.1 - 0.053 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Rib/alpha-like repeat Peptidase_M9_N PF08453.10 EGE06706.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M9 N-terminal AA_permease PF00324.21 EGE06707.1 - 5.2e-131 437.5 44.8 5.9e-131 437.4 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE06707.1 - 6.1e-26 91.2 50.8 8.9e-26 90.7 50.8 1.2 1 0 0 1 1 1 1 Amino acid permease FKBP_C PF00254.28 EGE06710.1 - 1.6e-11 44.4 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PepSY_2 PF13670.6 EGE06712.1 - 0.047 13.7 2.0 0.074 13.1 2.0 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain K_channel_TID PF07941.11 EGE06712.1 - 1.1 9.7 10.6 2.3 8.8 9.8 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Nucleo_P87 PF07267.11 EGE06712.1 - 3.3 6.4 5.5 3.8 6.3 5.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-actin_cap_A PF01267.17 EGE06714.1 - 2e-88 296.3 0.0 2.2e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit COesterase PF00135.28 EGE06715.1 - 9.5e-91 305.2 0.0 1.1e-90 305.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE06715.1 - 6e-09 36.1 1.1 2.5e-08 34.0 0.3 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Trp_oprn_chp PF09534.10 EGE06715.1 - 0.47 10.2 6.3 1.2 8.9 6.3 1.7 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2213 PF09979.9 EGE06716.1 - 0.019 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) HECT PF00632.25 EGE06719.1 - 3.1e-78 263.4 0.0 2.2e-77 260.6 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 EGE06719.1 - 0.0098 14.5 0.1 0.0098 14.5 0.1 2.3 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 EGE06719.1 - 0.028 14.7 0.3 4 8.0 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EGE06719.1 - 0.061 13.8 0.1 0.53 10.9 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 EGE06719.1 - 0.09 12.9 9.7 32 4.7 0.1 6.5 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat HAD PF12710.7 EGE06720.1 - 3.4e-27 96.1 0.0 4.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EGE06720.1 - 0.00012 21.7 0.0 0.00065 19.3 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 EGE06720.1 - 0.00038 19.9 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 EGE06720.1 - 0.16 12.3 1.3 12 6.1 1.3 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase BTB PF00651.31 EGE06721.1 - 0.00034 20.8 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RTA1 PF04479.13 EGE06723.1 - 8.1e-35 120.3 6.7 1.4e-34 119.5 6.7 1.3 1 0 0 1 1 1 1 RTA1 like protein Claudin_3 PF06653.11 EGE06723.1 - 0.054 13.4 4.6 0.13 12.2 4.6 1.7 1 0 0 1 1 1 0 Tight junction protein, Claudin-like RhlB PF12300.8 EGE06724.1 - 0.016 15.3 0.2 0.025 14.7 0.2 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB GHMP_kinases_C PF08544.13 EGE06724.1 - 0.035 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 GHMP kinases C terminal Ceramidase PF05875.12 EGE06725.1 - 1.7e-105 352.2 10.3 2e-105 352.0 10.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 EGE06725.1 - 0.063 11.6 1.1 0.078 11.2 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_6 PF12697.7 EGE06726.1 - 3.4e-10 40.9 0.0 5.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE06726.1 - 0.00034 20.0 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 IL8 PF00048.20 EGE06726.1 - 0.11 12.7 0.6 0.24 11.6 0.6 1.6 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Abhydrolase_1 PF00561.20 EGE06726.1 - 0.12 12.0 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ndr PF03096.14 EGE06726.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family RTT107_BRCT_5 PF16770.5 EGE06727.1 - 4e-35 119.7 0.0 3.5e-31 107.0 0.0 4.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EGE06727.1 - 1.2e-31 108.5 1.5 2e-17 62.9 0.3 5.7 5 1 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 EGE06727.1 - 1.6e-31 108.5 0.0 1.9e-08 34.5 0.0 6.8 6 1 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGE06727.1 - 1.5e-30 105.5 0.0 5.1e-05 23.6 0.0 6.4 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGE06727.1 - 4e-08 33.4 0.0 0.055 13.8 0.0 4.5 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGE06727.1 - 0.018 15.1 0.4 4.5 7.4 0.0 3.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Ofd1_CTDD PF10637.9 EGE06727.1 - 0.08 12.3 0.0 0.3 10.4 0.0 1.8 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term ESCRT-II PF05871.12 EGE06728.1 - 1.2e-51 174.7 1.0 1.3e-51 174.5 0.4 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit Methyltransf_4 PF02390.17 EGE06729.1 - 6.3e-47 159.2 0.1 9.1e-46 155.5 0.1 2.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGE06729.1 - 0.001 19.7 0.0 0.0099 16.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE06729.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE06729.1 - 0.0075 15.8 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGE06729.1 - 0.013 16.3 0.0 0.044 14.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGE06729.1 - 0.061 14.0 0.0 4.9 7.9 0.0 3.3 4 0 0 4 4 4 0 Methyltransferase domain LIM PF00412.22 EGE06730.1 - 5.5e-27 93.8 19.6 2e-10 40.8 2.8 4.0 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.6 EGE06730.1 - 0.0081 16.6 0.1 0.0081 16.6 0.1 2.5 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain DZR PF12773.7 EGE06730.1 - 1.3 9.1 25.4 29 4.8 3.2 4.6 2 1 1 3 3 3 0 Double zinc ribbon MFS_1 PF07690.16 EGE06731.1 - 6.5e-21 74.6 46.6 2.9e-12 46.2 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGE06731.1 - 9.3e-09 34.3 25.9 9.5e-06 24.4 8.0 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGE06731.1 - 0.0035 16.2 17.4 0.058 12.2 0.3 2.7 2 1 0 2 2 2 2 MFS_1 like family RNB PF00773.19 EGE06732.1 - 1.4e-97 326.9 0.2 2.5e-97 326.1 0.2 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EGE06732.1 - 4.9e-28 97.7 0.1 1.5e-27 96.1 0.1 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGE06732.1 - 1.2e-26 92.5 1.1 2.9e-26 91.2 1.1 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EGE06732.1 - 3.5e-21 75.0 0.0 9.5e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGE06732.1 - 1.9e-12 47.6 0.5 8.3e-12 45.5 0.2 2.2 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 EGE06732.1 - 2.7e-10 40.2 0.1 1.7e-06 28.1 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain ESSS PF10183.9 EGE06733.1 - 7.2e-15 55.1 0.0 8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ACOX PF01756.19 EGE06734.1 - 7.8e-46 155.9 0.0 1.3e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGE06734.1 - 1.8e-30 106.1 0.9 3.8e-30 105.0 0.9 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EGE06734.1 - 8.3e-12 45.2 0.0 3.1e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGE06734.1 - 7.6e-07 29.5 0.1 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain CAP_N PF01213.19 EGE06735.1 - 3.9 6.9 6.2 5.5 6.4 6.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EGE06735.1 - 6.7 6.7 5.8 11 6.0 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 EGE06735.1 - 7.7 6.0 5.9 12 5.4 5.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal AIP3 PF03915.13 EGE06736.1 - 2.8e-153 510.9 3.7 2.8e-153 510.9 3.7 2.1 3 0 0 3 3 3 1 Actin interacting protein 3 MIP-T3_C PF17749.1 EGE06736.1 - 0.014 15.4 0.6 0.014 15.4 0.6 4.1 4 0 0 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region Lectin_N PF03954.14 EGE06736.1 - 0.051 13.3 2.3 0.12 12.1 0.1 2.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Syntaxin_2 PF14523.6 EGE06736.1 - 0.29 11.5 6.8 1.8 9.0 0.1 4.1 3 1 2 5 5 5 0 Syntaxin-like protein Med11 PF10280.9 EGE06736.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.5 3 0 0 3 3 3 0 Mediator complex protein RasGAP_C PF03836.15 EGE06736.1 - 7.2 6.8 13.5 0.47 10.6 0.3 4.2 5 0 0 5 5 5 0 RasGAP C-terminus LsmAD PF06741.13 EGE06737.1 - 1.5e-27 96.0 6.0 4.4e-27 94.4 6.0 1.9 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 EGE06737.1 - 8.2e-20 70.7 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribonuclease PF00545.20 EGE06738.1 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.4 1 1 0 1 1 1 1 ribonuclease Pkinase PF00069.25 EGE06739.1 - 1.4e-10 41.0 0.0 3.3e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EGE06739.1 - 5.5e-07 29.3 1.7 0.16 12.3 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGE06739.1 - 6.8e-06 26.2 0.0 3.4e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 EGE06739.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 EGE06739.1 - 0.00013 22.4 0.1 4.3 7.9 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 EGE06739.1 - 0.00071 19.9 0.4 0.22 11.9 0.1 3.9 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.6 EGE06739.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CoA_trans PF01144.23 EGE06739.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase Adaptin_N PF01602.20 EGE06739.1 - 0.17 10.4 0.0 1.6 7.2 0.0 1.9 1 1 1 2 2 2 0 Adaptin N terminal region TelA PF05816.11 EGE06740.1 - 0.0023 17.1 6.4 0.0023 17.1 6.4 2.2 3 0 0 3 3 3 1 Toxic anion resistance protein (TelA) SR-25 PF10500.9 EGE06740.1 - 0.011 15.4 20.8 0.011 15.4 20.8 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGE06740.1 - 0.02 15.5 7.9 0.02 15.5 7.9 3.3 3 0 0 3 3 3 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 EGE06740.1 - 2.1 6.7 6.4 3.8 5.8 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Golgin_A5 PF09787.9 EGE06740.1 - 4.8 6.6 34.7 0.083 12.4 11.9 3.0 3 0 0 3 3 3 0 Golgin subfamily A member 5 YscO PF07321.12 EGE06740.1 - 7.9 6.4 40.0 0.24 11.3 12.5 4.0 4 0 0 4 4 4 0 Type III secretion protein YscO Acetyltransf_1 PF00583.25 EGE06741.1 - 1.3e-11 44.8 0.0 1.8e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE06741.1 - 3.1e-08 33.6 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE06741.1 - 3.9e-07 29.9 0.0 6.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGE06741.1 - 1.7e-05 25.2 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE06741.1 - 0.0028 17.7 0.1 0.0051 16.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SUR7 PF06687.12 EGE06743.1 - 1.5e-35 122.8 6.9 1.5e-35 122.8 6.9 1.3 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EGE06743.1 - 0.0056 16.6 4.4 0.0056 16.6 4.4 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 MadL PF03817.13 EGE06743.1 - 0.12 12.4 2.5 0.12 12.4 0.5 1.9 2 0 0 2 2 2 0 Malonate transporter MadL subunit DUF924 PF06041.11 EGE06744.1 - 1.7e-49 168.4 0.1 2e-49 168.2 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) PEMT PF04191.13 EGE06745.1 - 1.8e-34 118.3 1.9 1.2e-33 115.6 1.2 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.11 EGE06746.1 - 7.7e-33 113.7 0.1 7.7e-33 113.7 0.1 2.9 3 0 0 3 3 3 1 RXT2-like, N-terminal Ribosomal_L6 PF00347.23 EGE06747.1 - 4.1e-23 81.9 6.5 7.6e-11 42.5 0.4 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.24 EGE06748.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_1 PF00561.20 EGE06749.1 - 6e-09 35.9 0.0 1.9e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE06749.1 - 0.00026 20.3 0.0 0.0015 17.9 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Gryzun PF07919.12 EGE06750.1 - 2e-215 717.0 0.0 2.6e-215 716.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EGE06750.1 - 7.2e-86 288.0 2.6 2.9e-76 256.5 2.5 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EGE06750.1 - 0.0015 18.5 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking PhoD PF09423.10 EGE06751.1 - 3.5e-07 29.6 0.1 0.00057 19.0 0.1 2.7 2 1 0 2 2 2 2 PhoD-like phosphatase DUF3220 PF11516.8 EGE06751.1 - 0.12 12.5 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Rhomboid PF01694.22 EGE06752.1 - 9.6e-23 80.8 8.6 2.5e-22 79.5 6.7 2.0 2 0 0 2 2 2 1 Rhomboid family SlyX PF04102.12 EGE06753.1 - 0.03 14.9 2.6 1.6 9.4 1.3 2.3 2 0 0 2 2 2 0 SlyX NIF PF03031.18 EGE06754.1 - 2.8e-44 150.6 0.0 5e-36 123.8 0.0 2.3 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Aminotran_5 PF00266.19 EGE06755.1 - 3.7e-28 98.5 0.0 4.8e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGE06755.1 - 0.0056 15.9 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II KR PF08659.10 EGE06755.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 KR domain DUF2203 PF09969.9 EGE06756.1 - 0.068 13.9 1.1 0.36 11.5 0.1 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) RSS_P20 PF11757.8 EGE06756.1 - 0.072 13.5 0.1 0.46 11.0 0.1 2.1 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain HsbA PF12296.8 EGE06756.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A WW PF00397.26 EGE06757.1 - 3.5e-35 119.8 27.2 5.3e-13 48.8 5.7 4.4 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EGE06757.1 - 3.8e-20 72.1 0.0 9.7e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.22 EGE06758.1 - 1.5e-07 31.1 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 EGE06758.1 - 0.007 15.3 2.2 0.0075 15.2 2.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein EMP24_GP25L PF01105.24 EGE06758.1 - 0.014 15.3 0.8 0.018 15.0 0.8 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Med9 PF07544.13 EGE06758.1 - 0.021 14.9 3.6 0.024 14.7 3.2 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Nup54 PF13874.6 EGE06758.1 - 0.027 14.6 0.5 0.032 14.3 0.5 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.19 EGE06758.1 - 0.065 11.1 0.9 0.066 11.1 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG6 PF06419.11 EGE06758.1 - 0.067 11.4 0.8 0.075 11.2 0.8 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 FapA PF03961.13 EGE06758.1 - 0.077 11.6 0.2 0.08 11.5 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EGE06758.1 - 0.11 12.5 2.3 0.13 12.4 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MMPL PF03176.15 EGE06758.1 - 0.23 10.3 0.1 0.25 10.2 0.1 1.0 1 0 0 1 1 1 0 MMPL family DivIC PF04977.15 EGE06758.1 - 0.32 10.8 3.4 0.5 10.2 3.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 EGE06758.1 - 0.35 11.3 2.3 0.74 10.3 2.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 EGE06758.1 - 3.1 8.1 4.8 4.9 7.4 4.8 1.3 1 0 0 1 1 1 0 Haemolysin XhlA SUZ PF12752.7 EGE06759.1 - 2.7e-14 53.7 12.6 2.7e-14 53.7 12.6 4.8 4 1 0 4 4 4 1 SUZ domain R3H PF01424.22 EGE06759.1 - 4e-08 33.1 0.0 8.7e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.6 EGE06760.1 - 1.9e-05 24.5 2.5 1.9e-05 24.5 2.5 2.3 2 1 0 2 2 2 1 Zinc knuckle cwf18 PF08315.12 EGE06761.1 - 7.2e-45 153.0 10.2 1.1e-44 152.4 10.2 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor KicB PF03882.14 EGE06761.1 - 0.011 15.9 0.9 0.047 13.9 0.2 2.1 2 0 0 2 2 2 0 MukF winged-helix domain UPF0254 PF06787.11 EGE06761.1 - 0.09 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) PPR_2 PF13041.6 EGE06762.1 - 7.3e-23 80.5 0.6 3.4e-10 39.9 0.0 5.2 4 1 1 5 5 5 3 PPR repeat family PPR PF01535.20 EGE06762.1 - 3.3e-14 52.1 0.0 0.00046 20.2 0.0 5.0 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 EGE06762.1 - 7.2e-09 35.6 0.0 0.0016 18.4 0.0 3.2 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EGE06762.1 - 1.1e-08 34.6 0.0 0.0013 18.4 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EGE06762.1 - 2.8e-07 30.1 0.0 0.00034 20.0 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP DUF1242 PF06842.12 EGE06763.1 - 3.5e-16 58.7 0.1 5.5e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 EGE06764.1 - 2.5e-23 81.9 0.0 3.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 EGE06764.1 - 0.011 16.2 0.1 0.021 15.3 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 EGE06764.1 - 0.074 13.4 0.1 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGE06764.1 - 0.081 13.3 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein UTP25 PF06862.12 EGE06765.1 - 9.2e-138 459.9 0.1 5.6e-103 345.2 0.2 2.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EGE06765.1 - 0.00082 19.2 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase EamA PF00892.20 EGE06766.1 - 3.9e-16 59.5 21.0 1.3e-08 35.1 9.2 2.2 1 1 1 2 2 2 2 EamA-like transporter family CTP_transf_like PF01467.26 EGE06767.1 - 9.8e-30 103.6 0.0 1.9e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EGE06767.1 - 0.13 11.4 0.2 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase IHABP4_N PF16174.5 EGE06767.1 - 1.1 9.8 12.0 4 8.0 9.7 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal PP2C PF00481.21 EGE06768.1 - 1.9e-63 214.5 0.0 2.8e-51 174.6 0.0 2.8 1 1 1 2 2 2 2 Protein phosphatase 2C CDC45 PF02724.14 EGE06768.1 - 0.046 12.0 1.2 0.063 11.6 1.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_1 PF00583.25 EGE06769.1 - 9.7e-15 54.8 0.1 1.7e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE06769.1 - 1.2e-12 47.9 0.0 1.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE06769.1 - 1.3e-10 41.5 0.0 1.8e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE06769.1 - 2e-08 34.1 0.1 3.4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EGE06769.1 - 0.00056 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGE06769.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE06769.1 - 0.0036 17.4 0.1 0.0072 16.4 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGE06769.1 - 0.049 13.4 0.2 0.08 12.7 0.2 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 EGE06769.1 - 0.083 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.8 EGE06770.1 - 4.3e-26 90.4 1.5 4.9e-26 90.3 1.5 1.0 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CUE PF02845.16 EGE06771.1 - 1.2e-11 44.1 0.0 2.9e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 CUE domain eRF1_2 PF03464.15 EGE06771.1 - 0.044 14.1 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 2 HA2 PF04408.23 EGE06772.1 - 1.9e-17 63.5 0.0 3.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGE06772.1 - 2.2e-14 53.6 0.0 4.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGE06772.1 - 5e-12 46.2 0.0 1.8e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE06772.1 - 2.6e-05 24.1 0.1 6.9e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EGE06772.1 - 0.00033 20.5 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGE06772.1 - 0.00034 20.9 0.1 0.0019 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE06772.1 - 0.0016 18.8 0.0 0.0038 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EGE06772.1 - 0.0058 16.2 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EGE06772.1 - 0.037 13.1 0.0 0.1 11.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EGE06772.1 - 0.059 13.9 0.0 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PITH PF06201.13 EGE06773.1 - 5.2e-43 146.9 0.0 6.2e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 EGE06774.1 - 9.5e-30 103.5 9.8 1.2e-29 103.2 9.8 1.1 1 0 0 1 1 1 1 Snf7 DHDPS PF00701.22 EGE06774.1 - 0.013 14.3 0.3 0.026 13.3 0.2 1.4 1 1 0 1 1 1 0 Dihydrodipicolinate synthetase family MtaB PF12176.8 EGE06774.1 - 0.41 9.4 2.4 3.9 6.2 0.1 2.1 2 0 0 2 2 2 0 Methanol-cobalamin methyltransferase B subunit AAA PF00004.29 EGE06775.1 - 4e-91 302.3 0.0 1.3e-45 155.1 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE06775.1 - 2.5e-18 65.6 2.0 9.9e-09 34.9 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGE06775.1 - 3.5e-14 53.5 1.1 0.00019 21.9 0.0 4.7 4 2 1 5 5 4 2 AAA ATPase domain RuvB_N PF05496.12 EGE06775.1 - 2.9e-13 49.9 0.0 5.4e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGE06775.1 - 1.7e-11 44.5 0.8 0.0075 16.5 0.0 5.3 3 2 2 5 5 4 2 AAA domain AAA_2 PF07724.14 EGE06775.1 - 9.2e-11 42.2 0.0 0.00031 20.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGE06775.1 - 1e-10 41.9 0.0 3.3e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGE06775.1 - 4.8e-10 39.6 0.3 0.00086 19.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGE06775.1 - 4.9e-09 35.8 0.0 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGE06775.1 - 6.4e-08 33.0 0.0 0.0064 16.9 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGE06775.1 - 1.5e-07 31.5 0.0 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGE06775.1 - 3.2e-07 30.9 0.0 0.012 16.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EGE06775.1 - 5.3e-07 30.0 0.0 0.0074 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGE06775.1 - 7.4e-07 28.7 1.9 0.022 14.1 0.1 2.8 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGE06775.1 - 8.3e-07 28.9 0.1 0.059 13.1 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGE06775.1 - 9.7e-07 28.3 0.0 0.033 13.5 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 EGE06775.1 - 1.2e-06 28.5 0.0 0.004 17.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGE06775.1 - 9e-06 25.7 0.0 0.14 12.1 0.0 3.4 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 EGE06775.1 - 1e-05 25.5 0.0 0.078 13.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGE06775.1 - 1.6e-05 24.9 0.0 0.086 12.8 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EGE06775.1 - 3.9e-05 23.3 0.0 0.13 11.8 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EGE06775.1 - 4.8e-05 23.9 0.0 0.18 12.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Cytidylate_kin2 PF13189.6 EGE06775.1 - 5.3e-05 23.4 0.0 0.017 15.3 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_25 PF13481.6 EGE06775.1 - 6.9e-05 22.5 0.6 1.2 8.6 0.0 3.9 3 1 1 4 4 4 2 AAA domain ATPase PF06745.13 EGE06775.1 - 8e-05 22.1 0.1 0.68 9.2 0.0 3.2 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.26 EGE06775.1 - 9.5e-05 22.2 0.0 0.38 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 EGE06775.1 - 0.00012 22.5 1.0 0.19 12.2 0.0 3.3 3 1 0 3 3 2 1 AAA domain PhoH PF02562.16 EGE06775.1 - 0.0004 19.9 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein TniB PF05621.11 EGE06775.1 - 0.00041 19.8 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AFG1_ATPase PF03969.16 EGE06775.1 - 0.00045 19.2 0.0 0.088 11.7 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase AAA_11 PF13086.6 EGE06775.1 - 0.00047 20.0 0.1 1.2 8.9 0.0 2.6 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.22 EGE06775.1 - 0.00051 19.3 0.0 0.99 8.5 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain SKI PF01202.22 EGE06775.1 - 0.0007 19.7 0.0 0.8 9.8 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase Viral_helicase1 PF01443.18 EGE06775.1 - 0.00089 19.1 0.0 0.6 9.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGE06775.1 - 0.00095 19.1 0.0 1.8 8.4 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGE06775.1 - 0.00099 18.9 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EGE06775.1 - 0.0011 19.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 EGE06775.1 - 0.0011 18.1 0.0 0.049 12.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EGE06775.1 - 0.0021 17.2 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EGE06775.1 - 0.012 15.9 1.7 3.5 8.0 0.2 3.1 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EGE06775.1 - 0.019 14.8 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EGE06775.1 - 0.024 14.6 0.0 8.7 6.3 0.0 2.8 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGE06775.1 - 0.028 14.9 1.3 5.6 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Vps4_C PF09336.10 EGE06775.1 - 0.052 13.5 0.4 1.8 8.6 0.1 3.2 2 1 1 3 3 3 0 Vps4 C terminal oligomerisation domain IPT PF01745.16 EGE06775.1 - 0.056 12.8 0.1 7.6 5.8 0.0 2.6 3 0 0 3 3 2 0 Isopentenyl transferase DUF2075 PF09848.9 EGE06775.1 - 0.078 12.2 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EGE06775.1 - 0.11 12.4 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EGE06775.1 - 0.13 11.9 0.3 17 5.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGE06775.1 - 0.16 11.7 0.1 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase BET PF17035.5 EGE06775.1 - 1.7 8.9 4.6 3.1 8.1 0.7 3.2 4 0 0 4 4 3 0 Bromodomain extra-terminal - transcription regulation BOP1NT PF08145.12 EGE06776.1 - 3.1e-105 351.8 6.9 5.2e-105 351.1 6.9 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGE06776.1 - 8.3e-21 73.9 8.4 1.1e-09 38.7 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06776.1 - 5.7e-05 23.3 0.0 0.032 14.5 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGE06776.1 - 0.067 13.7 2.6 16 6.1 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Zn_clus PF00172.18 EGE06777.1 - 5e-08 32.9 7.2 9e-08 32.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.13 EGE06778.1 - 5.3e-29 101.2 0.7 5.3e-29 101.2 0.7 2.4 2 1 0 2 2 2 1 Leo1-like protein Mob1_phocein PF03637.17 EGE06779.1 - 4.9e-52 176.4 0.0 1.1e-51 175.2 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family IF-2B PF01008.17 EGE06780.1 - 7.3e-59 199.3 6.2 1.1e-48 165.9 3.5 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 EGE06781.1 - 3.2e-50 168.5 1.0 4e-50 168.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 EGE06782.1 - 9e-19 67.1 0.0 2.2e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) THUMP PF02926.17 EGE06782.1 - 0.013 15.6 0.6 0.019 15.1 0.6 1.2 1 0 0 1 1 1 0 THUMP domain AIM5 PF17050.5 EGE06783.1 - 2.6e-11 44.2 0.2 4.1e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Ribosomal_L17 PF01196.19 EGE06784.1 - 3.7e-34 117.5 0.0 8.2e-34 116.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 EGE06784.1 - 0.042 14.1 0.1 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Metallophos_2 PF12850.7 EGE06785.1 - 3.6e-13 50.0 0.0 4.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF202 PF02656.15 EGE06788.1 - 3.9e-14 52.8 4.5 3.9e-14 52.8 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EGE06788.1 - 1.4 8.8 10.0 0.23 11.3 5.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Tctex-1 PF03645.13 EGE06789.1 - 1.8e-35 121.2 0.1 2.3e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.32 EGE06790.1 - 1.2e-34 117.7 19.3 1.2e-09 38.6 0.2 8.5 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06790.1 - 9.9e-09 35.4 0.8 0.016 15.5 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE06790.1 - 2.4e-06 26.5 3.6 0.052 12.2 0.1 4.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGE06790.1 - 6.3e-06 25.3 0.6 3.4e-05 23.0 0.1 2.2 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EGE06790.1 - 0.0011 18.0 0.1 1.7 7.5 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EGE06790.1 - 0.092 12.5 4.1 0.2 11.4 0.4 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split HPS3_N PF14761.6 EGE06790.1 - 0.19 11.3 0.0 0.92 9.0 0.0 2.1 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 Filament PF00038.21 EGE06791.1 - 0.088 12.4 0.7 0.14 11.7 0.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein HNH_2 PF13391.6 EGE06792.1 - 1.9e-06 27.9 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease SAT PF16073.5 EGE06793.1 - 6.3e-74 248.7 1.6 9.5e-74 248.1 0.1 2.2 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EGE06793.1 - 4.3e-36 125.0 0.0 7.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGE06793.1 - 1.7e-34 118.3 0.1 4.5e-34 117.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGE06793.1 - 2.6e-34 118.9 0.0 3.3e-18 66.2 0.0 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Thioesterase PF00975.20 EGE06793.1 - 2e-27 96.8 0.0 5.7e-27 95.3 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 EGE06793.1 - 2e-17 63.4 0.0 3.3e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EGE06793.1 - 1.3e-13 51.1 7.9 9.1e-07 29.1 0.4 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGE06793.1 - 6.3e-08 33.1 0.1 1.7e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EGE06793.1 - 0.0012 19.5 0.3 0.0086 16.7 0.1 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGE06793.1 - 0.022 14.6 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold FMO-like PF00743.19 EGE06794.1 - 1.9e-64 218.0 0.0 2.4e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE06794.1 - 6.1e-13 48.7 0.0 3.2e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE06794.1 - 3.6e-11 42.8 0.0 2.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE06794.1 - 8.4e-07 28.4 0.2 3e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGE06794.1 - 0.00094 19.2 0.0 0.48 10.4 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EGE06794.1 - 0.0024 17.2 0.1 1.4 8.2 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EGE06794.1 - 0.0055 17.2 0.4 0.11 13.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EGE06794.1 - 0.019 15.1 0.1 0.043 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 EGE06794.1 - 0.019 15.2 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ELFV_dehydrog PF00208.21 EGE06794.1 - 0.05 13.3 0.1 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGE06794.1 - 0.078 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EGE06794.1 - 0.079 12.5 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cas_Csa5 PF09702.10 EGE06794.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) NAD_binding_7 PF13241.6 EGE06794.1 - 0.12 12.8 0.0 4.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Methyltransf_11 PF08241.12 EGE06794.1 - 0.17 12.5 0.0 0.37 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.20 EGE06794.1 - 0.18 11.8 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M17_N PF02789.17 EGE06794.1 - 0.21 11.4 0.1 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain adh_short PF00106.25 EGE06795.1 - 3.9e-35 121.1 0.4 3e-34 118.2 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE06795.1 - 2.2e-32 112.5 0.3 4.7e-30 104.9 0.3 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE06795.1 - 2.2e-08 34.2 0.1 4.6e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGE06795.1 - 0.02 15.1 0.1 0.035 14.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGE06795.1 - 0.028 13.9 0.0 0.058 12.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EGE06795.1 - 0.25 11.9 0.7 0.5 11.0 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.22 EGE06796.1 - 1.4e-24 86.7 1.1 2.1e-10 40.9 0.0 3.3 2 1 1 3 3 3 3 Fasciclin domain HHV-1_VABD PF16852.5 EGE06796.1 - 0.028 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Herpes viral adaptor-to-host cellular mRNA binding domain Cu-oxidase_3 PF07732.15 EGE06797.1 - 2e-38 131.0 1.7 3e-38 130.5 0.4 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE06797.1 - 1.5e-24 86.3 12.2 2e-21 76.1 0.5 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE06797.1 - 7.4e-19 68.4 0.1 2.1e-18 67.0 0.1 1.8 1 1 0 1 1 1 1 Multicopper oxidase DUF4087 PF13316.6 EGE06797.1 - 0.075 13.5 0.0 1.4 9.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4087) Nop53 PF07767.11 EGE06799.1 - 0.11 11.9 8.4 0.12 11.7 8.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FCP1_C PF09309.10 EGE06799.1 - 0.23 11.3 6.9 0.28 11.0 6.9 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Methyltransf_2 PF00891.18 EGE06801.1 - 1.4e-26 93.1 0.0 2.4e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGE06801.1 - 0.022 15.4 0.0 0.19 12.4 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain CheR PF01739.18 EGE06801.1 - 0.062 12.8 0.0 0.2 11.1 0.0 1.8 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 EGE06801.1 - 0.066 14.0 0.0 0.34 11.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 EGE06802.1 - 5.2e-39 134.2 46.6 1.7e-38 132.5 46.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06802.1 - 9.1e-11 41.3 30.0 5.7e-10 38.7 6.9 3.6 2 1 1 3 3 3 3 Sugar (and other) transporter Fungal_trans PF04082.18 EGE06803.1 - 1.4e-12 47.3 1.8 2.7e-12 46.3 1.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06803.1 - 6.1e-08 32.6 12.7 1.2e-07 31.8 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 EGE06804.1 - 2e-17 63.2 2.1 4e-17 62.2 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE06804.1 - 2e-06 27.8 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 EGE06805.1 - 6.5e-09 35.8 12.0 1.3e-08 34.9 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 EGE06805.1 - 3e-07 30.2 6.7 3e-07 30.2 6.7 1.6 1 1 0 1 1 1 1 Aflatoxin regulatory protein HNF-1_N PF04814.13 EGE06805.1 - 0.16 12.6 1.0 0.85 10.2 0.3 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RGS12_usC PF16612.5 EGE06805.1 - 2.3 8.7 9.3 0.63 10.5 1.4 2.7 3 0 0 3 3 3 0 C-terminal unstructured region of RGS12 Glyco_hydro_75 PF07335.11 EGE06806.1 - 0.038 14.3 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 p450 PF00067.22 EGE06807.1 - 6.4e-24 84.5 0.0 3e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.19 EGE06809.1 - 4.2e-53 180.2 0.0 5.3e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGE06809.1 - 2.6e-30 105.7 0.0 3.4e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE06809.1 - 5.9e-19 68.6 0.2 5.9e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGE06809.1 - 1.1e-09 37.9 0.8 2.6e-08 33.4 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EGE06809.1 - 1.9e-07 30.5 0.0 3.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGE06809.1 - 7.3e-06 26.0 0.0 9.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGE06809.1 - 1.5e-05 24.3 0.2 0.00011 21.4 0.2 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGE06809.1 - 0.00014 21.8 0.7 0.0017 18.3 0.7 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGE06809.1 - 0.0042 16.6 0.1 0.0076 15.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EGE06809.1 - 0.0078 15.8 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EGE06809.1 - 0.026 14.8 0.2 0.062 13.6 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain PglD_N PF17836.1 EGE06809.1 - 0.041 14.5 0.9 0.12 13.1 0.7 1.9 2 0 0 2 2 2 0 PglD N-terminal domain Transket_pyr PF02779.24 EGE06810.1 - 1.3e-42 145.4 0.0 2.1e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGE06810.1 - 1.3e-31 109.1 0.0 3.1e-31 107.8 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EGE06810.1 - 0.0086 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF4200 PF13863.6 EGE06811.1 - 0.0036 17.7 23.4 0.0036 17.7 23.4 4.2 2 1 2 4 4 4 3 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 EGE06811.1 - 0.3 11.4 38.3 0.015 15.6 11.7 2.9 2 1 0 2 2 2 0 Zinc finger-containing protein DUF21 PF01595.20 EGE06812.1 - 4.3e-30 104.7 0.0 6.6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGE06812.1 - 0.0017 18.7 0.1 0.52 10.8 0.0 2.9 2 0 0 2 2 2 2 CBS domain His_Phos_1 PF00300.22 EGE06813.1 - 1.5e-15 57.4 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1799 PF08809.11 EGE06813.1 - 0.083 13.1 0.4 0.21 11.8 0.1 1.8 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) Methyltransf_25 PF13649.6 EGE06813.1 - 0.17 12.6 0.0 0.38 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HECT PF00632.25 EGE06814.1 - 3.8e-68 230.2 0.0 2.1e-67 227.8 0.0 2.2 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) PG_binding_1 PF01471.18 EGE06815.1 - 0.0096 16.1 0.0 1.4 9.2 0.0 2.9 2 0 0 2 2 2 2 Putative peptidoglycan binding domain tRNA-synt_2 PF00152.20 EGE06816.1 - 1.4e-54 185.4 0.0 4.6e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE06816.1 - 5.2e-10 39.2 0.0 1.1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGE06816.1 - 0.1 12.0 0.2 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) BTB PF00651.31 EGE06817.1 - 9.2e-08 32.3 0.0 4.1e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 EGE06817.1 - 0.0022 18.2 0.0 0.0042 17.2 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain PCI PF01399.27 EGE06818.1 - 4.9e-10 39.9 0.0 9.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 EGE06818.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Ribosomal_L18A PF01775.17 EGE06819.1 - 2.5e-54 182.5 1.4 3.1e-54 182.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF2887 PF11103.8 EGE06819.1 - 0.027 14.5 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) NAD_binding_1 PF00175.21 EGE06820.1 - 1.8e-31 109.0 0.0 2.8e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGE06820.1 - 4.7e-24 84.6 0.0 9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGE06820.1 - 1.9e-08 34.5 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HMG_box PF00505.19 EGE06821.1 - 2.1e-11 44.0 2.5 2.1e-11 44.0 2.5 2.2 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGE06821.1 - 4.2e-07 30.5 2.3 4.2e-07 30.5 2.3 2.4 2 0 0 2 2 2 1 HMG-box domain Plasmodium_Vir PF05795.11 EGE06821.1 - 0.81 9.0 5.2 1.2 8.4 5.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Amidohydro_1 PF01979.20 EGE06822.1 - 1e-72 245.4 0.2 1.6e-72 244.7 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EGE06822.1 - 2.9e-54 182.6 1.1 5.7e-54 181.6 1.1 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EGE06822.1 - 4.7e-40 135.6 0.0 8.4e-40 134.8 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EGE06822.1 - 1.1e-10 41.7 0.0 2.8e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EGE06822.1 - 2e-07 30.9 0.1 0.00016 21.2 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Lactamase_B_2 PF12706.7 EGE06823.1 - 1.6e-07 31.1 0.0 3.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGE06823.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 EGE06823.1 - 0.00086 19.5 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase NicO PF03824.16 EGE06824.1 - 3.4 6.9 7.8 5.2 6.3 7.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 EGE06824.1 - 6.3 6.1 15.9 11 5.4 15.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NPR2 PF06218.11 EGE06825.1 - 1.4e-134 449.2 0.0 1e-133 446.4 0.0 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Rox3 PF08633.10 EGE06825.1 - 0.4 10.9 2.2 1.3 9.3 2.6 1.5 2 0 0 2 2 2 0 Rox3 mediator complex subunit Ada3 PF10198.9 EGE06826.1 - 6.1e-52 175.3 0.0 6.1e-52 175.3 0.0 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF572 PF04502.13 EGE06826.1 - 0.0034 17.1 2.9 0.0068 16.1 2.9 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_2 PF13639.6 EGE06827.1 - 1.5e-10 41.2 8.4 2.7e-10 40.4 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGE06827.1 - 1.3e-08 34.5 1.4 2.6e-08 33.5 1.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGE06827.1 - 6.1e-07 29.2 5.2 1.1e-06 28.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE06827.1 - 9.9e-06 25.4 2.9 1.8e-05 24.6 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE06827.1 - 1.4e-05 24.8 3.7 2.5e-05 24.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE06827.1 - 6.5e-05 22.9 3.6 6.5e-05 22.9 3.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGE06827.1 - 0.0011 19.2 7.1 0.0033 17.7 7.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGE06827.1 - 0.0054 16.8 2.0 0.012 15.7 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGE06827.1 - 0.019 14.8 5.3 0.036 13.9 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LapA_dom PF06305.11 EGE06827.1 - 0.12 12.2 2.3 0.3 10.9 2.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-C3HC4_4 PF15227.6 EGE06827.1 - 0.31 11.3 4.1 0.65 10.2 4.1 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGE06827.1 - 0.36 10.7 11.2 0.58 10.1 8.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EGE06827.1 - 5.5 6.7 6.4 0.65 9.7 1.2 2.1 2 0 0 2 2 2 0 P-11 zinc finger FRG1 PF06229.12 EGE06828.1 - 4.8e-53 179.7 0.0 6.3e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EGE06828.1 - 0.087 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Fascin domain ADH_N PF08240.12 EGE06829.1 - 4.9e-35 119.7 4.2 6e-35 119.4 2.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE06829.1 - 6.6e-16 58.5 0.0 1.1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGE06829.1 - 8.1e-12 45.1 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGE06829.1 - 7.5e-06 27.0 0.0 1.2e-05 26.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EGE06829.1 - 0.004 17.4 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGE06829.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EGE06829.1 - 0.046 13.0 1.0 0.069 12.4 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain NADH_4Fe-4S PF10589.9 EGE06829.1 - 1.2 9.3 3.6 0.38 10.9 0.4 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HECT PF00632.25 EGE06830.1 - 1.1e-68 232.1 0.0 1.4e-68 231.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.17 EGE06831.1 - 7.5e-89 296.5 12.2 9.3e-89 296.2 12.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 FXMRP1_C_core PF12235.8 EGE06831.1 - 3.4 8.3 9.4 0.39 11.3 3.3 2.0 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal AAA_assoc_2 PF16193.5 EGE06832.1 - 0.0017 18.7 0.6 0.0042 17.4 0.6 1.7 1 0 0 1 1 1 1 AAA C-terminal domain WD40 PF00400.32 EGE06833.1 - 4.7e-30 103.2 11.5 2.1e-07 31.5 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06833.1 - 3.1e-13 49.8 0.0 0.0002 21.6 0.0 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGE06833.1 - 0.00092 18.9 0.0 0.0058 16.2 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain EF-hand_1 PF00036.32 EGE06834.1 - 1.3e-13 49.4 3.7 3.1e-06 26.3 0.4 3.3 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 EGE06834.1 - 1.2e-11 44.2 4.4 2.2e-11 43.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 EGE06834.1 - 1.1e-10 41.8 7.2 3.4e-08 33.8 1.7 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGE06834.1 - 3.4e-10 39.0 3.4 0.00018 21.2 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGE06834.1 - 5.5e-07 28.8 1.9 0.0022 17.4 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGE06834.1 - 1.9e-05 24.4 4.6 0.0063 16.3 0.4 3.7 4 0 0 4 4 4 2 EF-hand domain pair C1_2 PF03107.16 EGE06834.1 - 0.0072 16.6 3.8 0.015 15.6 3.8 1.5 1 0 0 1 1 1 1 C1 domain HemY_N PF07219.13 EGE06834.1 - 0.12 12.6 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus MFS_1 PF07690.16 EGE06835.1 - 5.4e-51 173.6 65.5 2.4e-49 168.1 47.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE06835.1 - 5.9e-14 51.8 9.2 5.9e-14 51.8 9.2 3.5 4 0 0 4 4 4 2 Sugar (and other) transporter TMEM220 PF15071.6 EGE06835.1 - 0.61 10.9 3.4 4 8.2 3.2 2.7 1 1 0 1 1 1 0 Transmembrane family 220, helix Peptidase_M24 PF00557.24 EGE06836.1 - 5.5e-49 166.7 0.0 6.6e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGE06836.1 - 1.6e-19 69.9 5.3 3.1e-19 69.0 5.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGE06836.1 - 0.002 18.2 6.0 0.002 18.2 6.0 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EGE06836.1 - 1.7 8.6 4.8 4 7.4 4.8 1.7 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.19 EGE06837.1 - 1.4e-15 57.4 0.0 3.4e-14 52.9 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGE06837.1 - 9.3e-05 22.2 0.0 0.0082 15.8 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGE06837.1 - 0.00051 19.5 1.0 0.03 13.7 0.3 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EGE06837.1 - 0.0032 16.6 0.0 0.007 15.5 0.0 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGE06837.1 - 0.0039 16.0 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 EGE06837.1 - 0.0056 15.8 0.0 0.012 14.7 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EGE06837.1 - 0.0064 16.7 0.1 0.037 14.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE06837.1 - 0.0075 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE06837.1 - 0.017 15.7 0.1 0.48 11.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGE06837.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.24 EGE06839.1 - 6.4e-82 275.8 22.3 7.4e-82 275.6 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE06839.1 - 8.9e-13 47.9 40.2 3.2e-10 39.5 34.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGE06839.1 - 0.0035 16.3 5.3 0.0035 16.3 5.3 2.3 2 0 0 2 2 2 1 MFS_1 like family Ribosomal_S8 PF00410.19 EGE06840.1 - 2.3e-14 53.4 0.0 3.9e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 PIP5K PF01504.18 EGE06842.1 - 2.2e-36 125.5 0.8 1.4e-27 96.6 1.0 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGE06842.1 - 7.9e-32 110.5 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EGE06842.1 - 5.8e-15 55.2 4.1 5.8e-15 55.2 4.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger DZR PF12773.7 EGE06842.1 - 0.33 11.0 6.8 0.18 11.8 2.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EGE06842.1 - 2.1 8.3 10.9 0.021 14.7 2.9 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPP1 PF10341.9 EGE06843.1 - 1.6e-19 69.9 0.0 3.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF523 PF04463.12 EGE06843.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF523) DUF1769 PF08588.10 EGE06847.1 - 8.2e-27 93.2 0.3 1.4e-26 92.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Iso_dh PF00180.20 EGE06848.1 - 4.5e-97 325.3 0.0 9.6e-97 324.2 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.14 EGE06848.1 - 0.18 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PK PF00224.21 EGE06851.1 - 1.2e-173 576.8 5.1 1.6e-173 576.5 5.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGE06851.1 - 8.9e-39 132.3 0.0 5.3e-38 129.9 0.0 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGE06851.1 - 8.5e-05 21.8 0.3 0.00027 20.2 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EGE06851.1 - 0.0037 16.3 0.1 0.041 12.9 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF218 PF02698.17 EGE06851.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.9 1 1 0 1 1 1 0 DUF218 domain SUR7 PF06687.12 EGE06852.1 - 1.7e-42 145.5 1.1 2.1e-42 145.2 1.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tweety PF04906.13 EGE06852.1 - 0.068 11.8 0.1 0.3 9.7 0.0 1.9 2 0 0 2 2 2 0 Tweety Ribosomal_S17_N PF16205.5 EGE06855.1 - 3.1e-33 114.0 0.4 5.8e-33 113.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGE06855.1 - 1.1e-26 92.7 0.9 2e-26 91.9 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.6 EGE06856.1 - 0 1055.9 46.8 0 1055.4 46.8 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EGE06856.1 - 2.9e-118 394.3 1.3 2.9e-118 394.3 1.3 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF745 PF05335.13 EGE06856.1 - 0.0064 16.2 3.0 0.0064 16.2 3.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF745) DUF4407 PF14362.6 EGE06856.1 - 8.2 5.7 9.2 4.9 6.4 5.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pil1 PF13805.6 EGE06857.1 - 7.3e-126 419.1 0.0 1e-125 418.6 0.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EGE06857.1 - 0.089 12.2 1.3 0.17 11.3 0.6 1.7 1 1 0 2 2 2 0 FAM92 protein XPG_N PF00752.17 EGE06858.1 - 9e-35 119.2 0.0 2.2e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGE06858.1 - 3.6e-25 88.2 0.0 9.8e-25 86.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGE06858.1 - 0.00031 21.3 0.0 0.0012 19.4 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 EGE06858.1 - 0.027 14.8 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family WD40 PF00400.32 EGE06859.1 - 7.6e-14 51.9 12.4 5.4e-06 27.0 0.4 8.7 9 0 0 9 9 9 4 WD domain, G-beta repeat DUF5554 PF17709.1 EGE06859.1 - 0.0072 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5554) LSM PF01423.22 EGE06860.1 - 1e-08 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE06860.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 Ataxin 2 SM domain STPPase_N PF16891.5 EGE06861.1 - 3.5e-15 56.2 0.0 6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 EGE06861.1 - 4.3e-08 33.9 0.2 1.9e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase WD40 PF00400.32 EGE06862.1 - 5.4e-19 68.2 14.3 0.00018 22.3 0.1 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE06862.1 - 8.8e-17 61.2 0.0 7.3e-08 32.6 0.0 5.5 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE06862.1 - 3.8e-05 23.7 0.3 0.011 15.6 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EGE06862.1 - 0.00046 20.0 0.5 0.0016 18.2 0.5 2.0 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 EGE06862.1 - 0.019 13.9 0.0 23 3.8 0.0 3.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGE06862.1 - 0.048 13.6 4.8 8.7 6.4 0.3 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGE06862.1 - 0.13 11.5 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain DUF3128 PF11326.8 EGE06863.1 - 1.2 9.5 6.4 9.3 6.7 0.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) YabA PF06156.13 EGE06864.1 - 0.32 11.7 2.0 1.3 9.7 2.0 2.1 1 0 0 1 1 1 0 Initiation control protein YabA F-box-like PF12937.7 EGE06865.1 - 0.0009 19.1 0.9 0.0021 17.9 0.3 2.0 2 0 0 2 2 2 1 F-box-like PRANC PF09372.10 EGE06865.1 - 0.2 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain MG2 PF01835.19 EGE06866.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 MG2 domain Gpr1_Fun34_YaaH PF01184.19 EGE06867.1 - 4.1e-80 268.3 18.3 5.2e-80 267.9 18.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.16 EGE06868.1 - 1.3e-34 119.4 0.4 3.1e-18 65.8 0.1 2.2 1 1 1 2 2 2 2 ANTH domain ENTH PF01417.20 EGE06868.1 - 1.1e-09 38.4 0.0 4.8e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 ENTH domain Memo PF01875.17 EGE06870.1 - 5.7e-60 202.8 0.0 7.2e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Rad4 PF03835.15 EGE06872.1 - 1.4e-15 57.3 2.9 2.3e-15 56.5 2.9 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EGE06872.1 - 9.2e-14 51.9 0.4 2e-13 50.8 0.4 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box PF00646.33 EGE06873.1 - 0.11 12.4 0.6 0.22 11.4 0.6 1.5 1 0 0 1 1 1 0 F-box domain ANAPC4_WD40 PF12894.7 EGE06874.1 - 1.9e-09 37.7 0.4 0.18 12.1 0.0 6.2 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE06874.1 - 3.7e-07 30.7 13.6 1.6 9.7 0.0 9.1 10 1 0 10 10 10 2 WD domain, G-beta repeat PQQ_2 PF13360.6 EGE06874.1 - 2.8e-06 27.1 0.2 2.9e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 EGE06874.1 - 0.015 14.3 0.0 0.33 9.9 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EGE06874.1 - 0.054 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ PF01011.21 EGE06874.1 - 0.19 11.7 1.3 42 4.3 0.1 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Treacle PF03546.14 EGE06874.1 - 3.9 6.2 8.1 0.15 10.9 2.1 1.6 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle IHABP4_N PF16174.5 EGE06875.1 - 2.6 8.6 9.6 3 8.4 8.3 1.7 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Cyclin_N PF00134.23 EGE06877.1 - 7.8e-36 122.6 0.1 1.7e-35 121.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGE06877.1 - 5.3e-09 36.2 6.0 1.4e-08 34.8 2.1 2.8 2 1 0 2 2 2 1 Cyclin, C-terminal domain TMPIT PF07851.13 EGE06877.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Acyl_transf_3 PF01757.22 EGE06879.1 - 0.00046 19.4 10.4 0.00099 18.3 10.4 1.6 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.6 EGE06879.1 - 0.056 13.9 0.1 0.056 13.9 0.1 1.8 2 0 0 2 2 2 0 Capsule biosynthesis CapC Pyr_redox_2 PF07992.14 EGE06880.1 - 9.7e-14 51.3 0.0 4e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE06880.1 - 0.0007 18.9 0.7 1.6 7.9 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE06880.1 - 0.0085 14.8 0.0 0.024 13.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EGE06880.1 - 0.022 15.0 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGE06880.1 - 0.044 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF4892 PF16234.5 EGE06880.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) NAD_binding_9 PF13454.6 EGE06880.1 - 0.18 11.8 0.6 5.1 7.1 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding MPDZ_u10 PF16667.5 EGE06882.1 - 0.043 14.7 4.1 0.057 14.3 4.1 1.3 1 1 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein NAPRTase_N PF17767.1 EGE06884.1 - 0.0032 17.9 1.7 0.0052 17.2 1.7 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FKBP_C PF00254.28 EGE06885.1 - 3.9e-33 113.6 0.0 4.7e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.28 EGE06886.1 - 5.2e-17 61.8 0.0 8.1e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Beta-lactamase PF00144.24 EGE06887.1 - 5.7e-26 91.5 0.1 8e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Zip PF02535.22 EGE06888.1 - 4.7e-67 226.6 6.0 5.5e-67 226.4 6.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Tom37 PF10568.9 EGE06889.1 - 3e-38 130.9 0.0 7.1e-38 129.7 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EGE06889.1 - 1e-09 38.0 0.0 7.3e-09 35.3 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE06889.1 - 0.0038 17.9 0.0 0.022 15.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Peptidase_C3 PF00548.20 EGE06893.1 - 0.12 12.3 0.0 4.5 7.2 0.0 2.2 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) APH PF01636.23 EGE06894.1 - 1.8e-05 24.8 0.0 2.4e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 EGE06895.1 - 9.5e-14 51.9 0.0 4e-13 49.8 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family YdaS_antitoxin PF15943.5 EGE06895.1 - 0.13 12.2 0.3 22 5.0 0.0 3.3 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT F-box PF00646.33 EGE06896.1 - 0.00085 19.1 0.3 0.0026 17.6 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGE06896.1 - 0.2 11.6 2.4 0.64 10.0 0.1 2.6 2 0 0 2 2 2 0 F-box-like HSDR_N PF04313.14 EGE06898.1 - 0.00042 20.3 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) HNH_2 PF13391.6 EGE06900.1 - 2.2e-08 34.1 0.0 6.9e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease EH_Signature PF15611.6 EGE06900.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.5 1 1 0 1 1 1 0 EH_Signature domain DNA_pol3_gamma3 PF12169.8 EGE06901.1 - 0.13 12.2 0.0 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III DUF5643 PF18705.1 EGE06903.1 - 0.069 13.1 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5643) His_Phos_1 PF00300.22 EGE06907.1 - 0.00025 20.8 1.3 1.9 8.1 0.0 4.0 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) Peptidase_M35 PF02102.15 EGE06909.1 - 1.4e-106 356.5 8.8 1.7e-106 356.2 8.8 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGE06909.1 - 4.1e-46 157.1 3.2 8.9e-46 156.0 3.2 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGE06909.1 - 1.1e-05 25.2 5.3 9.4e-05 22.1 5.3 2.0 1 1 0 1 1 1 1 Putative peptidase family AKAP28 PF14469.6 EGE06910.1 - 0.12 12.1 0.0 0.75 9.6 0.0 2.0 2 0 0 2 2 2 0 28 kDa A-kinase anchor UPF0160 PF03690.13 EGE06912.1 - 1.2e-123 412.8 0.0 1.4e-123 412.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Trimer_CC PF08954.11 EGE06912.1 - 0.0089 15.6 0.1 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 Trimerisation motif 5_nucleotid_C PF02872.18 EGE06913.1 - 9.6e-38 129.9 0.0 1.5e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGE06913.1 - 1.7e-06 28.7 0.0 3.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Allexi_40kDa PF05549.11 EGE06914.1 - 0.13 11.8 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Peptidase_C1_2 PF03051.15 EGE06915.1 - 1.8e-159 531.2 0.0 2.1e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGE06915.1 - 2.2e-09 37.7 0.3 4.7e-05 23.6 0.1 2.6 2 1 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 EGE06915.1 - 0.0068 17.0 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4296) Kinesin PF00225.23 EGE06916.1 - 1.5e-112 375.9 0.4 4.3e-112 374.3 0.4 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGE06916.1 - 1.7e-26 92.9 0.1 7.5e-26 90.9 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 EGE06916.1 - 0.04 14.0 0.2 0.14 12.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) LEA_6 PF10714.9 EGE06916.1 - 0.18 11.9 1.5 0.47 10.6 1.5 1.6 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Nbl1_Borealin_N PF10444.9 EGE06916.1 - 5.4 6.7 11.7 0.82 9.4 0.4 4.5 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal HAP1_N PF04849.13 EGE06916.1 - 9.1 5.4 51.7 0.089 12.0 19.5 3.8 2 1 0 3 3 3 0 HAP1 N-terminal conserved region Thiolase_N PF00108.23 EGE06917.1 - 2.1e-92 309.1 1.4 2.8e-92 308.8 1.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE06917.1 - 2.4e-37 127.3 0.7 2.4e-37 127.3 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGE06917.1 - 9.2e-05 22.1 0.4 0.00021 20.9 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGE06917.1 - 0.016 15.1 2.8 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 EGE06919.1 - 1.3e-51 173.9 0.0 1.5e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE06919.1 - 0.00071 19.3 0.0 0.0008 19.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGE06919.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 1 0 1 1 1 0 RWD domain Cation_efflux PF01545.21 EGE06920.1 - 1.2e-45 155.7 14.8 1.2e-45 155.7 14.8 2.4 2 1 0 2 2 2 1 Cation efflux family AveC_like PF17198.4 EGE06920.1 - 0.019 14.4 0.0 0.068 12.6 0.0 2.0 1 0 0 1 1 1 0 Spirocyclase AveC-like SPW PF03779.14 EGE06920.1 - 0.16 11.6 8.9 0.045 13.4 0.7 3.7 3 0 0 3 3 3 0 SPW repeat Zip PF02535.22 EGE06920.1 - 0.59 9.3 39.1 2 7.5 4.5 3.5 1 1 2 3 3 3 0 ZIP Zinc transporter Glyco_trans_4_4 PF13579.6 EGE06921.1 - 4.4e-11 43.5 0.6 7.4e-11 42.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EGE06921.1 - 5e-08 33.1 1.4 8e-08 32.5 1.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGE06921.1 - 9.2e-07 29.4 0.0 6.4e-06 26.6 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGE06921.1 - 0.0021 18.4 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGE06921.1 - 0.0027 17.3 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 TFIIIC_delta PF12657.7 EGE06922.1 - 1.6e-44 152.1 0.1 4.1e-44 150.7 0.1 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Mito_carr PF00153.27 EGE06923.1 - 4.5e-58 193.2 4.6 6.9e-19 67.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LtrA PF06772.11 EGE06924.1 - 4.2e-24 85.4 23.9 4.2e-24 85.4 23.9 2.0 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF2976 PF11190.8 EGE06924.1 - 0.014 15.2 0.5 0.014 15.2 0.5 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) DUF4212 PF13937.6 EGE06924.1 - 0.4 11.1 9.3 0.57 10.6 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) HNH_2 PF13391.6 EGE06925.1 - 2.7e-13 49.8 0.1 5e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease ADP_PFK_GK PF04587.15 EGE06925.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region TraF_2 PF13729.6 EGE06925.1 - 0.14 11.5 0.0 0.51 9.7 0.0 1.8 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Ribosomal_L16 PF00252.18 EGE06926.1 - 7.1e-10 39.0 0.0 8.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AA_permease PF00324.21 EGE06927.1 - 2e-62 211.3 27.1 9e-62 209.2 27.1 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE06927.1 - 3.2e-22 79.0 24.5 4.5e-22 78.5 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease 7tm_1 PF00001.21 EGE06927.1 - 0.17 11.2 0.0 0.17 11.2 0.0 3.1 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) TspO_MBR PF03073.15 EGE06927.1 - 2 8.5 11.0 0.34 10.9 6.0 2.4 2 1 0 2 2 2 0 TspO/MBR family UQ_con PF00179.26 EGE06929.1 - 1.8e-44 150.8 0.0 2e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE06929.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGE06929.1 - 0.32 11.3 2.3 0.42 10.9 2.3 1.6 1 1 0 1 1 1 0 RWD domain CFEM PF05730.11 EGE06930.1 - 4.9e-13 49.0 7.3 7e-13 48.5 7.3 1.2 1 0 0 1 1 1 1 CFEM domain Amidoligase_2 PF12224.8 EGE06932.1 - 5.9e-17 62.2 0.0 1.2e-16 61.2 0.0 1.5 1 1 0 1 1 1 1 Putative amidoligase enzyme CSTF_C PF14304.6 EGE06932.1 - 0.18 11.4 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal KASH PF10541.9 EGE06934.1 - 0.035 14.4 1.3 0.095 13.0 0.4 2.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain MFS_1 PF07690.16 EGE06935.1 - 5e-11 42.1 39.4 5.4e-11 42.0 38.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGE06935.1 - 5.9e-08 32.6 7.2 5.9e-08 32.6 7.2 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Sas10_Utp3 PF04000.15 EGE06936.1 - 9.8e-18 64.6 1.8 9.8e-18 64.6 1.8 2.4 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DNA_pol_phi PF04931.13 EGE06936.1 - 0.65 8.0 24.6 0.75 7.8 21.4 2.0 2 0 0 2 2 2 0 DNA polymerase phi Glypican PF01153.19 EGE06936.1 - 0.73 8.6 4.5 1.2 7.8 4.5 1.3 1 0 0 1 1 1 0 Glypican CENP-B_dimeris PF09026.10 EGE06936.1 - 1.6 9.2 13.0 3.8 8.0 13.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGE06936.1 - 8.9 5.5 14.3 21 4.3 14.3 1.5 1 0 0 1 1 1 0 NOA36 protein FMO-like PF00743.19 EGE06938.1 - 2.7e-14 52.5 0.0 1.1e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE06938.1 - 1.4e-13 50.8 0.0 6e-10 38.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE06938.1 - 7.6e-12 45.1 0.0 3.8e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE06938.1 - 5.1e-10 39.0 0.0 1.3e-07 31.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGE06938.1 - 7.2e-07 29.3 1.1 2.6e-05 24.3 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE06938.1 - 1.7e-06 28.5 1.8 0.042 14.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGE06938.1 - 5.4e-06 25.9 0.1 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EGE06938.1 - 0.00021 21.3 1.2 0.068 13.2 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EGE06938.1 - 0.0014 18.3 2.2 0.012 15.2 0.6 2.9 2 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGE06938.1 - 0.0064 16.9 0.0 0.078 13.4 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGE06938.1 - 0.0079 16.1 0.2 0.017 15.1 0.2 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGE06938.1 - 0.015 15.4 0.1 5.2 7.1 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGE06938.1 - 0.028 13.5 0.2 0.028 13.5 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EGE06938.1 - 0.15 10.7 1.3 1.2 7.8 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 EGE06938.1 - 0.62 9.3 1.6 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EGE06938.1 - 9 5.3 6.2 1 8.4 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NmrA PF05368.13 EGE06939.1 - 1e-38 133.2 0.0 1.7e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE06939.1 - 2.1e-14 53.8 0.0 2.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGE06939.1 - 0.0059 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGE06939.1 - 0.034 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Med3 PF11593.8 EGE06941.1 - 5.1 6.2 7.8 7 5.7 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 EGE06943.1 - 5.9e-35 120.8 50.2 5.9e-35 120.8 50.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE06943.1 - 2e-20 72.8 14.0 2.6e-20 72.4 14.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE06943.1 - 9.6e-13 47.8 10.1 9.6e-13 47.8 10.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EGE06943.1 - 0.75 8.0 10.5 2 6.6 5.2 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase_fungal PF17667.1 EGE06944.1 - 2.8e-99 332.7 0.0 4.3e-97 325.5 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EGE06944.1 - 5.7e-07 29.2 0.0 9.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE06944.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGE06944.1 - 0.0089 15.6 0.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family EMP70 PF02990.16 EGE06946.1 - 1.5e-193 644.2 4.1 1.9e-193 643.8 4.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 APH PF01636.23 EGE06947.1 - 1.1e-10 41.9 0.0 2.4e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGE06947.1 - 0.00043 19.7 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGE06947.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGE06947.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_1 PF00036.32 EGE06948.1 - 2.3e-26 89.3 9.6 2.7e-08 32.8 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGE06948.1 - 1.5e-25 86.9 2.7 3e-06 26.7 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EGE06948.1 - 1.7e-24 86.0 6.0 8.6e-16 58.2 0.6 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGE06948.1 - 1.1e-17 62.6 14.6 1.9e-05 24.0 0.0 4.8 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EGE06948.1 - 3.2e-16 58.9 9.9 3.2e-06 26.9 0.9 4.2 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGE06948.1 - 4.2e-09 36.3 4.6 0.001 19.0 0.1 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGE06948.1 - 8.7e-05 22.8 0.4 0.14 12.5 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGE06948.1 - 0.0033 17.7 0.9 0.52 10.7 0.2 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EGE06948.1 - 0.016 14.1 0.5 1.2 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 EGE06948.1 - 0.033 14.1 2.3 1.3 9.0 0.1 3.6 4 1 0 4 4 4 0 EF hand Med4 PF10018.9 EGE06949.1 - 2e-34 119.0 0.2 4.8e-34 117.7 0.1 1.6 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DNA_pol_phi PF04931.13 EGE06949.1 - 0.52 8.4 4.7 0.75 7.8 4.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 EGE06950.1 - 1.4e-27 96.6 36.3 3.7e-27 95.2 36.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE06950.1 - 0.0011 17.5 2.9 0.0014 17.2 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RabGAP-TBC PF00566.18 EGE06952.1 - 1.5e-49 168.6 0.0 5.5e-49 166.7 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain FAM76 PF16046.5 EGE06952.1 - 1.1 8.6 5.7 2.3 7.5 5.7 1.5 1 0 0 1 1 1 0 FAM76 protein APG6_N PF17675.1 EGE06952.1 - 2.9 8.4 15.9 0.59 10.7 5.9 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Acyl-CoA_dh_1 PF00441.24 EGE06953.1 - 6.4e-30 104.3 1.9 1.2e-29 103.5 1.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGE06953.1 - 4.2e-23 82.1 0.2 9.1e-23 81.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGE06953.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGE06953.1 - 1e-14 54.9 3.3 1.7e-14 54.3 0.9 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Reticulon PF02453.17 EGE06954.1 - 2.2e-27 96.0 5.8 3e-27 95.5 5.8 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.11 EGE06954.1 - 0.0067 15.5 4.7 0.011 14.8 3.7 1.5 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin SCAB_CC PF16712.5 EGE06954.1 - 0.097 12.5 0.3 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Phasin_2 PF09361.10 EGE06954.1 - 0.11 12.7 1.5 0.24 11.7 0.4 2.0 2 0 0 2 2 2 0 Phasin protein CDC27 PF09507.10 EGE06954.1 - 0.14 11.5 6.6 0.2 11.0 6.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_topoisoIV PF00521.20 EGE06956.1 - 1.4e-135 452.5 0.1 3.2e-135 451.3 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGE06956.1 - 4.9e-52 175.6 6.9 4.9e-52 175.6 6.9 2.5 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGE06956.1 - 1e-25 90.2 2.7 1e-25 90.2 2.7 2.0 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 EGE06956.1 - 4.9e-15 56.0 0.0 1.7e-14 54.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGE06956.1 - 5.4e-07 29.8 0.1 3.6e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 Toprim domain Mitofilin PF09731.9 EGE06956.1 - 0.0009 18.2 11.1 0.0009 18.2 11.1 3.8 3 1 0 3 3 3 1 Mitochondrial inner membrane protein INCENP_ARK-bind PF03941.15 EGE06957.1 - 9.1e-17 60.8 1.6 2.7e-16 59.2 0.9 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.7 EGE06958.1 - 2.5e-51 171.6 0.0 1.3e-34 118.1 0.0 3.3 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 EGE06958.1 - 3.3e-21 76.7 0.1 5.6e-20 72.8 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EGE06958.1 - 3.3e-12 46.6 0.3 6.1e-06 26.5 0.0 4.1 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 EGE06958.1 - 7.2e-11 41.8 3.5 6.2e-07 29.2 0.6 4.4 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EGE06958.1 - 3.4e-07 30.5 0.1 0.00025 21.3 0.0 3.3 3 0 0 3 3 3 1 PDZ domain Trypsin PF00089.26 EGE06958.1 - 0.0002 21.2 0.0 0.00074 19.4 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EGE06958.1 - 0.0052 16.7 0.2 0.4 10.7 0.2 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EGE06958.1 - 0.06 13.1 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DUF31 PF01732.16 EGE06958.1 - 0.13 11.8 0.3 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 EGE06958.1 - 0.18 10.5 1.0 0.3 9.7 0.1 1.7 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.12 EGE06959.1 - 1.2e-07 31.2 0.0 0.0049 16.5 0.0 2.6 2 0 0 2 2 2 2 SSXT protein (N-terminal region) K_channel_TID PF07941.11 EGE06959.1 - 6.4 7.3 11.7 0.83 10.2 2.7 2.8 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ABC_tran PF00005.27 EGE06961.1 - 7.5e-63 211.1 0.0 2.6e-32 112.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE06961.1 - 2.3e-57 194.7 14.1 2.3e-48 165.2 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGE06961.1 - 2.2e-11 43.6 0.7 0.00044 19.7 0.1 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGE06961.1 - 5e-07 29.8 0.0 0.005 16.6 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGE06961.1 - 6.6e-07 29.0 0.4 0.021 14.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE06961.1 - 1.3e-06 29.0 3.6 0.037 14.4 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGE06961.1 - 2e-06 27.8 0.1 0.031 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGE06961.1 - 2.1e-06 27.8 0.7 0.013 15.3 0.0 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGE06961.1 - 2.1e-06 28.0 2.5 0.019 15.2 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EGE06961.1 - 3.7e-06 26.8 1.3 0.24 11.1 1.5 3.7 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 EGE06961.1 - 2.1e-05 24.7 0.0 0.0061 16.7 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EGE06961.1 - 9.6e-05 23.0 0.2 0.15 12.5 0.3 2.4 2 0 0 2 2 2 2 AAA domain FAD_binding_4 PF01565.23 EGE06961.1 - 9.8e-05 22.1 0.2 9.8e-05 22.1 0.2 2.7 3 0 0 3 3 2 1 FAD binding domain AAA_5 PF07728.14 EGE06961.1 - 0.00048 20.1 0.0 0.5 10.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EGE06961.1 - 0.00063 19.1 0.1 1 8.6 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin ABC_ATPase PF09818.9 EGE06961.1 - 0.00068 18.5 0.4 0.0081 15.0 0.1 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.29 EGE06961.1 - 0.00098 19.6 2.3 4 7.9 1.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGE06961.1 - 0.0038 16.8 0.1 2.3 7.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EGE06961.1 - 0.0042 16.7 1.4 2.9 7.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGE06961.1 - 0.0044 17.2 0.1 2.7 8.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGE06961.1 - 0.0045 17.5 0.0 0.69 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGE06961.1 - 0.0074 16.2 0.1 0.056 13.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain PRK PF00485.18 EGE06961.1 - 0.02 14.7 0.3 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EGE06961.1 - 0.034 13.9 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGE06961.1 - 0.072 13.2 0.5 9 6.4 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGE06961.1 - 0.088 13.2 0.1 3.8 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Imm5 PF14423.6 EGE06961.1 - 0.12 12.5 0.1 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm5 AAA_28 PF13521.6 EGE06961.1 - 0.13 12.5 0.2 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGE06961.1 - 0.14 11.3 0.1 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Pkinase_fungal PF17667.1 EGE06962.1 - 2.7e-132 441.4 0.0 3.5e-132 441.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGE06962.1 - 0.00021 20.8 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.22 EGE06964.1 - 6.2e-45 153.8 0.0 7.7e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EGE06965.1 - 1.5e-15 57.0 0.5 2.3e-15 56.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE06965.1 - 7.2e-06 26.0 10.2 1.6e-05 24.9 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 EGE06966.1 - 8.5e-07 28.5 3.4 0.12 12.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.9 EGE06966.1 - 0.00034 19.5 0.3 0.00048 19.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EGE06966.1 - 0.0032 17.5 5.0 0.27 11.4 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE06966.1 - 0.16 12.2 4.1 0.071 13.3 1.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 peroxidase PF00141.23 EGE06968.1 - 1.1e-45 156.1 0.0 1.6e-45 155.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 EGE06968.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) COesterase PF00135.28 EGE06970.1 - 8.9e-61 206.3 0.0 1.1e-60 205.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE06970.1 - 0.0013 18.7 0.0 0.0078 16.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 EGE06971.1 - 1.6e-08 34.5 6.8 3.7e-08 33.4 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE06971.1 - 2.8e-06 26.4 0.8 5.3e-06 25.5 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridoxal_deC PF00282.19 EGE06972.1 - 4.2e-79 266.0 0.0 5.3e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGE06972.1 - 3.5e-05 22.9 0.0 5.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EGE06972.1 - 0.024 13.4 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EGE06972.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Nuc_deoxyri_tr2 PF15891.5 EGE06973.1 - 0.0029 17.9 3.2 0.003 17.8 2.2 1.5 1 1 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like DUF2072 PF09845.9 EGE06973.1 - 0.067 13.4 6.0 0.16 12.2 5.8 1.7 1 1 0 1 1 1 0 Zn-ribbon containing protein NBD_C PF17042.5 EGE06973.1 - 0.55 10.7 3.7 0.2 12.2 1.4 1.5 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain DUF1676 PF07898.13 EGE06973.1 - 0.72 9.9 3.5 0.83 9.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) APH PF01636.23 EGE06976.1 - 4e-13 49.8 1.8 2.3e-12 47.4 0.3 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE06976.1 - 5.3e-05 22.9 0.0 0.00014 21.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase BNR PF02012.20 EGE06977.1 - 0.027 14.4 1.2 0.078 13.0 0.2 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_61 PF03443.14 EGE06977.1 - 0.11 12.4 0.2 0.34 10.8 0.2 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 TruD PF01142.18 EGE06978.1 - 6.1e-59 199.9 0.0 7.9e-55 186.4 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Cupin_1 PF00190.22 EGE06979.1 - 3.7e-36 124.0 0.0 4.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EGE06979.1 - 1.6e-19 69.4 1.6 1.1e-08 34.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EGE06979.1 - 9.3e-05 22.3 1.2 0.035 14.0 0.2 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 EGE06979.1 - 9.6e-05 22.0 0.2 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) 3-HAO PF06052.12 EGE06979.1 - 0.029 14.0 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 EGE06979.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Tankyrase_bdg_C PF15327.6 EGE06980.1 - 0.16 12.5 5.1 0.22 11.9 4.8 1.3 1 1 0 1 1 1 0 Tankyrase binding protein C terminal domain Acetyltransf_10 PF13673.7 EGE06981.1 - 0.00032 20.6 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE06981.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE06981.1 - 0.014 15.9 0.0 0.023 15.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain P53_TAD PF08563.11 EGE06982.1 - 0.055 13.0 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 P53 transactivation motif RPE65 PF03055.15 EGE06983.1 - 1.9e-113 380.2 0.0 2.1e-113 380.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.9 EGE06984.1 - 3.4e-28 97.7 0.7 7.2e-28 96.7 0.2 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) FYDLN_acid PF09538.10 EGE06984.1 - 0.078 13.7 0.1 0.14 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3754 PF12576.8 EGE06984.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) BNIP2 PF12496.8 EGE06985.1 - 2.2 8.7 5.8 0.98 9.9 0.2 2.8 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 NUP50 PF08911.11 EGE06985.1 - 3.3 8.4 8.4 0.33 11.7 1.9 2.7 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Mtc PF03820.17 EGE06986.1 - 1.6e-115 385.5 0.0 1.8e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EGE06987.1 - 4.5e-07 29.5 0.1 2.2e-06 27.3 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain DPBB_1 PF03330.18 EGE06988.1 - 0.0014 18.9 0.0 0.0016 18.7 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGE06988.1 - 0.0063 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Barwin family FAD_binding_4 PF01565.23 EGE06989.1 - 1.7e-22 79.7 0.6 3e-22 78.8 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE06989.1 - 3.6e-13 49.4 0.3 8.6e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like CPSF73-100_C PF11718.8 EGE06990.1 - 1.5e-79 266.6 0.0 2.4e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGE06990.1 - 4.1e-31 107.5 0.0 9.4e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EGE06990.1 - 3.3e-22 79.5 0.8 4.3e-22 79.1 0.1 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EGE06990.1 - 1.7e-16 60.2 0.1 2.8e-16 59.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EGE06990.1 - 9.8e-05 22.0 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGE06990.1 - 0.00019 21.4 0.0 0.00089 19.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.14 EGE06991.1 - 1.3e-25 90.7 6.0 1.3e-24 87.4 6.0 2.4 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Transferase PF02458.15 EGE06994.1 - 1.4e-20 73.4 0.0 5.3e-18 64.9 0.0 3.2 2 1 0 2 2 2 2 Transferase family Peptidase_S41 PF03572.18 EGE06995.1 - 4.6e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 DUF1659 PF07872.11 EGE06995.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) Kdo PF06293.14 EGE06996.1 - 1.8e-07 30.7 0.2 1.8e-07 30.7 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE06996.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family MAP7 PF05672.11 EGE06996.1 - 0.13 12.0 27.8 0.33 10.6 27.8 1.6 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Pkinase PF00069.25 EGE06996.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain SMBP PF16785.5 EGE06996.1 - 0.48 10.7 6.0 0.93 9.7 6.0 1.4 1 0 0 1 1 1 0 Small metal-binding protein NCKAP5 PF15246.6 EGE06996.1 - 0.53 9.8 7.3 0.98 9.0 7.3 1.4 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Pro_CA PF00484.19 EGE06996.1 - 1.7 8.9 4.7 62 3.8 3.2 2.8 3 0 0 3 3 3 0 Carbonic anhydrase DUF874 PF05917.11 EGE06996.1 - 1.8 7.6 8.3 2.9 6.8 8.3 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) CiPC PF15800.5 EGE06996.1 - 4.1 7.0 13.9 9.1 5.9 2.7 3.1 3 0 0 3 3 3 0 Clock interacting protein circadian DUF2294 PF10057.9 EGE06997.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) DUF4395 PF14340.6 EGE06998.1 - 2 8.8 10.0 40 4.6 10.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) Peptidase_S8 PF00082.22 EGE07000.1 - 2.2e-33 115.8 15.0 6.7e-33 114.2 15.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE07000.1 - 1.7e-17 63.9 0.2 9.5e-17 61.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 AAT PF03417.16 EGE07001.1 - 3e-38 131.8 0.0 3.7e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 2OG-FeII_Oxy PF03171.20 EGE07002.1 - 1.1e-13 51.5 0.1 3.3e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGE07002.1 - 3.1e-13 50.5 0.0 4.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AMP-binding PF00501.28 EGE07003.1 - 5.2e-251 832.5 0.0 7.9e-88 294.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGE07003.1 - 5.3e-245 813.2 0.1 1.4e-94 317.3 0.4 4.7 5 0 0 5 5 5 4 Condensation domain PP-binding PF00550.25 EGE07003.1 - 1.8e-52 175.6 0.7 3.3e-17 62.6 0.1 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE07003.1 - 7e-26 91.0 0.0 1.3e-10 42.1 0.0 3.7 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EGE07003.1 - 8.6e-25 88.2 0.0 1.8e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EGE07003.1 - 0.00046 20.9 0.1 0.0019 18.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE07003.1 - 0.019 14.2 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AATase PF07247.12 EGE07003.1 - 0.021 13.4 0.0 0.084 11.4 0.0 2.0 1 0 0 1 1 1 0 Alcohol acetyltransferase Ank_2 PF12796.7 EGE07005.1 - 0.00089 19.8 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE07005.1 - 0.0023 18.2 0.0 0.0061 16.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE07005.1 - 0.0084 16.7 0.1 0.026 15.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) GST_N PF02798.20 EGE07006.1 - 7.6e-12 45.4 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE07006.1 - 3.1e-09 37.1 0.1 1.2e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE07006.1 - 6e-07 29.7 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE07006.1 - 1.6e-05 25.0 0.0 2.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE07006.1 - 0.0016 18.6 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE07006.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGE07006.1 - 0.14 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BTB_2 PF02214.22 EGE07007.1 - 6.4e-09 36.1 0.1 2.2e-05 24.7 0.0 2.7 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 EGE07007.1 - 0.012 15.8 0.0 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain Acetyltransf_1 PF00583.25 EGE07009.1 - 6.6e-11 42.5 0.0 9.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGE07009.1 - 5.7e-10 39.5 0.0 8.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGE07009.1 - 6.6e-10 39.0 0.0 9.4e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EGE07009.1 - 2.6e-07 31.3 0.0 4.6e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGE07009.1 - 5.1e-05 23.3 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EGE07009.1 - 6.9e-05 23.5 0.0 8.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE07009.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGE07009.1 - 0.00072 19.6 0.1 0.0012 18.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGE07009.1 - 0.038 13.4 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Methyltr_RsmB-F PF01189.17 EGE07010.1 - 3.2e-18 66.1 0.0 1.3e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F NDUF_B4 PF07225.12 EGE07011.1 - 7.9e-05 22.6 0.0 8.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.12 EGE07012.1 - 2.1e-50 170.6 0.0 2.6e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 EGE07013.1 - 8e-55 184.8 0.0 8e-55 184.8 0.0 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EGE07013.1 - 4.1e-12 45.4 2.5 4.1e-12 45.4 2.5 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.10 EGE07013.1 - 0.89 8.9 23.4 1.5 8.1 23.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MAJIN PF15077.6 EGE07013.1 - 6.7 6.4 10.8 11 5.7 10.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DEAD PF00270.29 EGE07014.1 - 6.9e-36 123.6 0.0 1.2e-17 64.2 0.0 2.8 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE07014.1 - 1.9e-19 70.1 0.0 1.8e-18 66.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE07014.1 - 3e-07 30.6 0.0 1.8e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Macoilin PF09726.9 EGE07014.1 - 3.3 6.1 21.8 0.012 14.2 2.7 2.1 2 0 0 2 2 2 0 Macoilin family PIGA PF08288.12 EGE07015.1 - 8.5e-46 154.5 1.5 8.5e-46 154.5 1.5 1.7 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EGE07015.1 - 1.6e-27 96.6 0.3 2.6e-27 95.9 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGE07015.1 - 7.6e-26 90.7 0.0 1.2e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGE07015.1 - 3.7e-23 82.4 0.1 6.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGE07015.1 - 2.2e-11 44.5 0.0 3.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGE07015.1 - 5.5e-06 26.5 0.1 1.3e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EGE07015.1 - 0.0015 18.9 0.0 0.0062 16.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arf PF00025.21 EGE07016.1 - 2.2e-40 137.9 0.0 9e-27 93.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGE07016.1 - 2.2e-12 47.3 0.0 6.6e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGE07016.1 - 1.2e-11 44.4 0.0 6.4e-05 22.3 0.0 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGE07016.1 - 9.6e-08 31.8 0.0 0.00051 19.7 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EGE07016.1 - 2.5e-07 30.8 0.0 2.6e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGE07016.1 - 8.9e-07 28.5 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGE07016.1 - 8.5e-06 25.4 0.0 0.00025 20.6 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGE07016.1 - 9.5e-06 25.2 0.0 5.3e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGE07016.1 - 0.035 13.9 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGE07016.1 - 0.035 13.5 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 EGE07016.1 - 0.036 13.6 0.0 0.083 12.4 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF4630 PF15443.6 EGE07016.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) AAA_24 PF13479.6 EGE07016.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGE07016.1 - 0.17 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RVT_1 PF00078.27 EGE07017.1 - 9.9e-11 41.6 2.9 2.2e-08 33.9 1.1 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.20 EGE07017.1 - 0.19 12.1 0.0 0.45 10.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3700 PF12481.8 EGE07018.1 - 0.00032 20.2 0.5 0.27 10.7 0.0 2.1 2 0 0 2 2 2 2 Aluminium induced protein Pkinase PF00069.25 EGE07019.1 - 1.1e-20 74.1 0.0 1e-08 34.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07019.1 - 1.9e-08 33.9 0.0 0.1 11.9 0.0 3.3 4 0 0 4 4 4 3 Protein tyrosine kinase Kinase-like PF14531.6 EGE07019.1 - 0.011 15.0 0.1 11 5.3 0.1 3.0 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 EGE07019.1 - 0.022 14.7 0.2 0.059 13.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_3 PF13738.6 EGE07020.1 - 0.00032 20.0 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07020.1 - 0.13 11.4 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Kelch_5 PF13854.6 EGE07026.1 - 6.3e-10 38.8 0.4 6.3e-10 38.8 0.4 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EGE07026.1 - 2.2e-05 24.4 1.7 0.002 18.1 0.1 4.0 2 2 1 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGE07026.1 - 3.3e-05 23.4 3.0 0.1 12.2 0.3 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EGE07026.1 - 0.0016 18.7 0.1 0.0016 18.7 0.1 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE07026.1 - 0.007 16.6 5.6 0.021 15.1 0.2 4.0 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EGE07026.1 - 0.016 15.1 0.4 9.3 6.4 0.1 4.1 4 0 0 4 4 4 0 Kelch motif Aldo_ket_red PF00248.21 EGE07027.1 - 1.7e-63 214.6 0.0 1.9e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 EGE07028.1 - 1.6e-22 80.3 13.3 1.6e-22 80.3 13.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily BCS1_N PF08740.11 EGE07030.1 - 1.2e-49 168.9 0.6 2.1e-48 164.8 0.9 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EGE07030.1 - 2.4e-16 60.3 0.0 4.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGE07030.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE07030.1 - 0.027 14.9 0.1 0.069 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGE07030.1 - 0.051 14.1 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Polyoma_lg_T_C PF06431.11 EGE07030.1 - 0.068 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus ATPase PF06745.13 EGE07030.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC HNH_2 PF13391.6 EGE07031.1 - 9.9e-08 32.0 0.1 3.1e-07 30.4 0.1 1.9 1 0 0 1 1 1 1 HNH endonuclease Zn_clus PF00172.18 EGE07032.1 - 2.6e-10 40.2 8.6 5e-10 39.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EGE07032.1 - 4.4e-05 22.6 0.1 8.5e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SRP19 PF01922.17 EGE07033.1 - 1.6e-32 112.3 0.0 3.7e-32 111.1 0.0 1.6 2 0 0 2 2 2 1 SRP19 protein TCTP PF00838.17 EGE07034.1 - 7.7e-68 228.0 2.7 8.6e-68 227.9 2.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein LsmAD PF06741.13 EGE07034.1 - 0.058 13.9 1.8 0.13 12.8 0.3 2.0 2 0 0 2 2 2 0 LsmAD domain GMC_oxred_N PF00732.19 EGE07035.1 - 5.2e-46 157.4 0.6 6.8e-46 157.0 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGE07035.1 - 2.2e-07 30.3 0.5 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGE07035.1 - 6.1e-05 22.4 0.2 0.00018 20.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE07035.1 - 0.00087 18.6 0.2 0.0096 15.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EGE07035.1 - 0.0041 16.4 0.1 0.0069 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGE07035.1 - 0.016 14.5 0.5 0.024 14.0 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE07035.1 - 0.028 14.6 0.7 0.087 13.1 0.7 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Toprim PF01751.22 EGE07036.1 - 1.9e-06 28.0 0.0 2.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Toprim domain DUF3357 PF11837.8 EGE07038.1 - 0.16 12.5 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF3915 PF13054.6 EGE07038.1 - 0.23 11.5 2.9 0.31 11.0 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 EGE07038.1 - 0.89 7.8 7.6 0.96 7.7 7.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF5326 PF17260.2 EGE07041.1 - 0.052 13.7 0.1 0.078 13.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Phosphodiest PF01663.22 EGE07042.1 - 8.2e-16 58.5 0.4 1.3e-15 57.9 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGE07042.1 - 8.8e-05 22.0 0.9 0.00015 21.2 0.9 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGE07042.1 - 0.00055 19.4 0.1 0.00091 18.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF2304 PF10066.9 EGE07042.1 - 0.65 10.2 7.4 21 5.4 0.4 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF3169 PF11368.8 EGE07042.1 - 2.1 7.8 6.4 1.6 8.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) cwf21 PF08312.12 EGE07043.1 - 5.9e-14 51.9 18.6 5.9e-14 51.9 18.6 2.5 3 1 0 3 3 3 1 cwf21 domain Atg14 PF10186.9 EGE07043.1 - 2.4 7.2 10.9 0.16 11.1 4.6 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HA2 PF04408.23 EGE07044.1 - 9.8e-28 96.6 0.1 9.8e-28 96.6 0.1 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGE07044.1 - 3.6e-12 46.5 0.0 9.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGE07044.1 - 4.4e-12 46.3 0.0 1.7e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE07044.1 - 4.6e-10 39.5 0.0 1.6e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGE07044.1 - 0.0023 18.3 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGE07044.1 - 0.0033 17.5 1.6 2 8.4 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGE07044.1 - 0.0074 16.8 0.0 0.0074 16.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 EGE07044.1 - 0.0099 16.2 0.5 0.036 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGE07044.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGE07044.1 - 0.074 12.1 0.2 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EGE07044.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGE07044.1 - 0.088 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family PAC3 PF10178.9 EGE07045.1 - 0.00017 21.6 0.0 0.00037 20.6 0.0 1.6 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 TLP1_add_C PF18313.1 EGE07046.1 - 6.1e-24 83.8 0.3 2.1e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Cohesin_load PF10345.9 EGE07048.1 - 3.6e-165 550.8 5.5 4.3e-165 550.6 5.5 1.0 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.6 EGE07048.1 - 0.026 14.2 0.0 0.076 12.7 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease TPR_4 PF07721.14 EGE07048.1 - 1.2 10.0 5.5 18 6.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGE07048.1 - 1.7 9.0 19.0 3.5 8.0 0.8 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Histone PF00125.24 EGE07049.1 - 1e-41 142.4 0.3 1.4e-41 142.0 0.3 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGE07049.1 - 2.2e-05 24.6 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGE07049.1 - 0.00035 20.9 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGE07049.1 - 0.0064 16.8 0.4 0.012 15.8 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGE07049.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 EGE07050.1 - 1.6e-47 161.9 5.7 1.9e-47 161.7 5.7 1.0 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.15 EGE07050.1 - 0.068 13.1 1.8 0.12 12.4 1.8 1.4 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa EMP70 PF02990.16 EGE07051.1 - 7.9e-187 622.0 0.0 1.1e-186 621.5 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.23 EGE07052.1 - 4.1e-19 68.1 0.0 6.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGE07052.1 - 7.4e-08 32.2 0.1 1.8e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGE07052.1 - 2.1e-05 24.2 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGE07052.1 - 0.0003 21.3 1.6 0.00047 20.7 0.0 2.0 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGE07052.1 - 0.0011 19.1 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EGE07052.1 - 0.015 15.2 1.1 0.015 15.2 1.1 3.0 2 1 1 3 3 3 0 STI1 domain HOIP-UBA PF16678.5 EGE07052.1 - 0.074 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 EGE07052.1 - 0.3 11.0 5.1 0.67 9.9 4.3 1.9 1 1 1 2 2 2 0 Spore germination GerD central core domain Corazonin PF17308.2 EGE07052.1 - 0.33 11.3 8.7 0.4 11.0 0.3 3.2 4 0 0 4 4 4 0 Pro-corazonin MMS1_N PF10433.9 EGE07053.1 - 1.2e-158 528.8 0.0 1.7e-158 528.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGE07053.1 - 3.6e-102 342.0 0.0 7.3e-101 337.7 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EGE07053.1 - 0.044 14.1 0.0 1.5 9.2 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CN_hydrolase PF00795.22 EGE07054.1 - 1.1e-31 110.1 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.12 EGE07055.1 - 1e-42 145.7 0.3 4.7e-42 143.5 0.2 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EGE07055.1 - 1e-24 87.1 1.0 1e-24 87.1 1.0 5.3 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EGE07055.1 - 1.1e-06 29.0 5.0 0.48 10.9 0.0 6.9 6 2 2 8 8 8 3 HEAT repeats Adaptin_N PF01602.20 EGE07055.1 - 0.021 13.4 13.2 0.0077 14.8 0.5 4.5 3 2 1 4 4 4 0 Adaptin N terminal region Nipped-B_C PF12830.7 EGE07055.1 - 0.35 10.8 4.6 29 4.5 0.0 4.7 5 0 0 5 5 5 0 Sister chromatid cohesion C-terminus HEAT PF02985.22 EGE07055.1 - 1.7 9.1 14.0 1.3 9.5 0.0 7.1 9 0 0 9 9 9 0 HEAT repeat NRDE-2 PF08424.10 EGE07056.1 - 1.5e-94 316.8 0.1 4.7e-93 311.8 0.0 2.7 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGE07056.1 - 0.00061 20.4 2.1 8.4 7.5 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGE07056.1 - 0.19 12.2 0.2 1.4 9.5 0.2 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGE07056.1 - 0.38 10.7 2.4 5.5 7.0 0.2 3.3 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 UDG PF03167.19 EGE07057.1 - 9.9e-19 67.8 0.0 5.5e-18 65.4 0.0 2.0 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.11 EGE07058.1 - 0.26 11.2 8.5 0.72 9.7 8.5 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.12 EGE07060.1 - 1.3e-23 83.9 0.0 2.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGE07060.1 - 1.1e-22 80.1 0.0 2.6e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGE07060.1 - 1.2e-20 73.9 10.0 2.5e-20 72.9 10.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EGE07060.1 - 0.045 14.1 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGE07060.1 - 0.046 14.4 0.0 5.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.18 EGE07061.1 - 1.4e-25 89.1 0.1 1.7e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 EGE07062.1 - 1.1e-22 81.2 0.0 2e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Nas2_N PF18265.1 EGE07063.1 - 1.3e-27 95.6 0.1 1.8e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 EGE07063.1 - 1e-05 25.8 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EGE07063.1 - 2.7e-05 23.9 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGE07063.1 - 0.002 18.4 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EGE07064.1 - 1.6e-49 167.6 0.0 1.9e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE07064.1 - 1.3e-29 102.9 0.1 3.1e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE07064.1 - 4.2e-11 42.6 0.0 6.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EGE07064.1 - 0.0003 21.1 0.1 0.0017 18.7 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EGE07064.1 - 0.00061 19.2 0.0 0.0008 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGE07064.1 - 0.00088 19.3 0.0 0.0018 18.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGE07064.1 - 0.0059 15.8 1.6 1.8 7.6 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit Pox_A32 PF04665.12 EGE07064.1 - 0.021 14.3 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EGE07064.1 - 0.031 14.2 0.0 7.3 6.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EGE07064.1 - 0.034 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGE07064.1 - 0.042 13.6 0.2 0.055 13.2 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGE07064.1 - 0.074 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EGE07064.1 - 0.083 12.9 0.0 0.22 11.6 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 EGE07064.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EGE07064.1 - 0.11 12.6 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EGE07064.1 - 0.15 11.3 0.3 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Septin SNF2_N PF00176.23 EGE07065.1 - 1.1e-60 205.3 0.4 2.3e-60 204.2 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE07065.1 - 2.4e-14 53.6 0.0 5.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGE07065.1 - 3.2e-08 33.3 1.8 3.2e-08 33.3 1.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE07065.1 - 3.3e-08 33.3 2.9 7.2e-08 32.2 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE07065.1 - 3.8e-06 26.7 3.5 8e-06 25.6 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGE07065.1 - 1.1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EGE07065.1 - 3.5e-05 24.0 3.8 8.5e-05 22.8 3.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGE07065.1 - 5.5e-05 23.0 3.5 0.00012 21.9 3.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGE07065.1 - 6e-05 23.0 2.0 0.00015 21.7 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGE07065.1 - 0.00081 19.2 4.1 0.0031 17.3 4.1 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGE07065.1 - 0.0019 18.0 3.6 0.0045 16.7 3.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGE07065.1 - 0.015 15.4 5.4 0.032 14.4 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGE07065.1 - 0.071 13.2 3.3 0.18 11.8 3.3 1.7 1 1 0 1 1 1 0 Double zinc ribbon CCDC50_N PF15295.6 EGE07065.1 - 0.75 10.0 7.7 2.1 8.5 7.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF1644 PF07800.12 EGE07065.1 - 2.5 8.2 4.8 27 4.8 2.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) F-box-like PF12937.7 EGE07066.1 - 0.00026 20.8 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EGE07066.1 - 0.12 12.3 1.2 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 F-box domain SCP2 PF02036.17 EGE07067.1 - 1.6e-24 86.3 0.1 1.9e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGE07067.1 - 0.00011 22.4 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EGE07067.1 - 0.017 15.5 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.18 EGE07068.1 - 6.3e-14 52.3 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EGE07068.1 - 0.0013 19.6 45.0 0.0039 18.0 21.6 11.4 3 3 6 9 9 9 4 Nucleoporin FG repeat region NUP50 PF08911.11 EGE07068.1 - 0.0067 17.1 2.4 0.0067 17.1 2.4 6.6 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) WH1 PF00568.23 EGE07068.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 WH1 domain TRAP_alpha PF03896.16 EGE07068.1 - 5.1 6.2 5.5 11 5.1 5.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_L31e PF01198.19 EGE07069.1 - 2.2e-41 140.0 0.5 2.7e-41 139.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.18 EGE07069.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel CN_hydrolase PF00795.22 EGE07070.1 - 2.4e-58 197.5 0.0 2.7e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Lipase_GDSL_2 PF13472.6 EGE07070.1 - 0.19 12.1 0.1 0.44 10.9 0.1 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.18 EGE07071.1 - 5.6e-09 35.4 2.6 8.8e-09 34.8 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE07071.1 - 3.6e-06 27.0 8.0 6.6e-06 26.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.11 EGE07071.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) FAD_binding_3 PF01494.19 EGE07072.1 - 4.3e-32 111.7 0.1 5.6e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGE07072.1 - 6.5e-08 31.9 1.4 2.6e-05 23.3 0.1 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EGE07072.1 - 9.8e-06 25.0 0.2 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGE07072.1 - 8.6e-05 21.7 0.1 0.00017 20.7 0.1 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGE07072.1 - 0.0018 18.4 0.5 0.0056 16.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE07072.1 - 0.0068 16.9 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE07072.1 - 0.038 13.2 0.1 0.091 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE07072.1 - 1 8.9 3.8 1.2 8.6 1.1 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase Thioesterase PF00975.20 EGE07073.1 - 1.6e-19 70.9 0.1 3.2e-19 70.0 0.1 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EGE07073.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE07073.1 - 6.5e-05 23.6 0.0 6.5e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox PF00070.27 EGE07073.1 - 0.059 13.9 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE07073.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.7 EGE07073.1 - 0.14 12.0 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Asp PF00026.23 EGE07074.1 - 6.8e-13 48.7 0.6 3.8e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGE07074.1 - 0.025 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal p450 PF00067.22 EGE07075.1 - 5.1e-49 167.3 0.1 6.4e-42 143.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2953 PF11167.8 EGE07075.1 - 0.12 12.5 0.1 0.4 10.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) AMP-binding PF00501.28 EGE07077.1 - 1e-79 268.1 0.0 1.5e-79 267.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EGE07077.1 - 1e-76 258.5 0.0 1.6e-76 257.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 EGE07077.1 - 4.7e-72 242.6 0.0 9.9e-72 241.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EGE07077.1 - 1.3e-61 208.4 0.0 2.1e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EGE07077.1 - 8e-60 201.8 0.2 3.3e-59 199.8 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EGE07077.1 - 3.7e-57 194.2 0.0 6.7e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGE07077.1 - 2.8e-36 125.0 0.0 6.1e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGE07077.1 - 1.1e-20 73.8 0.2 1.6e-10 41.2 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 EGE07077.1 - 3e-18 66.0 0.0 1.7e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 EGE07077.1 - 5.7e-18 65.1 0.0 4.7e-17 62.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE07077.1 - 9.3e-17 62.3 0.0 2.2e-15 57.9 0.0 3.3 4 0 0 4 4 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGE07077.1 - 9.2e-09 35.0 0.4 2.5e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07077.1 - 3.6e-06 26.7 0.0 8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EGE07077.1 - 0.00082 18.8 0.0 0.0023 17.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EGE07077.1 - 0.0037 18.2 0.0 0.0093 16.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KAsynt_C_assoc PF16197.5 EGE07077.1 - 0.012 16.0 0.1 0.064 13.7 0.0 2.2 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension DUF1233 PF06806.12 EGE07077.1 - 0.085 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) ATG2_CAD PF13329.6 EGE07082.1 - 2e-44 151.0 0.2 4.9e-44 149.8 0.2 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EGE07082.1 - 1.1e-25 89.7 0.3 4e-25 88.0 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGE07082.1 - 0.0021 17.9 0.0 0.0096 15.7 0.0 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal A_deaminase PF00962.22 EGE07083.1 - 1.1e-21 77.6 0.0 2.3e-21 76.5 0.0 1.5 2 0 0 2 2 2 1 Adenosine/AMP deaminase Mt_ATP-synt_B PF05405.14 EGE07083.1 - 0.068 12.8 1.3 0.12 12.0 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_S17 PF00366.20 EGE07084.1 - 1.6e-13 50.5 0.7 2.7e-13 49.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF737 PF05300.11 EGE07084.1 - 0.089 13.1 3.0 1.1 9.5 3.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF737) AAA PF00004.29 EGE07085.1 - 1.3e-36 125.9 0.0 2.2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGE07085.1 - 2.1e-11 43.7 0.0 1.1e-07 31.7 0.0 3.5 3 0 0 3 3 3 2 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGE07085.1 - 1.6e-08 34.2 0.0 4.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGE07085.1 - 5.7e-05 23.4 0.1 0.00042 20.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGE07085.1 - 9.6e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGE07085.1 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE07085.1 - 0.00021 21.7 1.4 0.0052 17.2 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGE07085.1 - 0.002 18.1 0.1 0.01 15.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGE07085.1 - 0.0036 16.6 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGE07085.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGE07085.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EGE07085.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EGE07085.1 - 0.061 13.9 0.0 0.18 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGE07085.1 - 0.068 12.6 0.0 2.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGE07085.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGE07085.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGE07085.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGE07085.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EGE07085.1 - 0.11 12.0 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGE07085.1 - 0.2 11.9 0.6 2.3 8.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain Sde2_N_Ubi PF13019.6 EGE07086.1 - 4.4e-67 225.0 0.1 1.2e-66 223.6 0.1 1.7 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain MMR_HSR1 PF01926.23 EGE07086.1 - 0.00015 21.8 0.4 0.33 11.0 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase S10_plectin PF03501.15 EGE07087.1 - 7.3e-41 138.2 0.1 8.8e-41 137.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.28 EGE07088.1 - 1.1e-28 100.4 0.2 1.5e-28 99.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGE07088.1 - 6.3e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGE07088.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 HIT PF01230.23 EGE07089.1 - 2.4e-16 60.3 0.0 3.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGE07089.1 - 1.2e-08 35.4 0.0 1.5e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGE07089.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 EGE07090.1 - 2.7e-38 131.2 0.0 5.7e-38 130.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE07090.1 - 6.5e-14 51.9 0.1 2e-13 50.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGE07090.1 - 2.6e-06 27.6 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF755 PF05501.11 EGE07090.1 - 0.037 14.3 1.4 0.037 14.3 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) DASH_Dam1 PF08653.10 EGE07091.1 - 1.1e-28 98.8 2.3 1.6e-28 98.2 2.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Aminopep PF10023.9 EGE07091.1 - 0.059 12.7 0.4 0.078 12.3 0.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase UCH PF00443.29 EGE07093.1 - 7.6e-53 179.6 0.1 1e-52 179.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07093.1 - 1.1e-23 84.3 3.1 7.6e-23 81.6 3.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGE07093.1 - 0.00012 22.4 0.7 0.00012 22.4 0.7 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein APH PF01636.23 EGE07094.1 - 1.4e-08 34.9 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE07094.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EGE07094.1 - 0.25 10.6 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_2 PF02230.16 EGE07095.1 - 1.2e-19 71.0 0.0 3.1e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGE07095.1 - 0.0054 16.4 0.0 0.025 14.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGE07095.1 - 0.0077 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGE07095.1 - 0.028 13.7 0.0 0.077 12.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LIP PF03583.14 EGE07095.1 - 0.092 12.0 0.1 0.68 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Rhomboid PF01694.22 EGE07096.1 - 4.6e-13 49.4 8.8 4.6e-13 49.4 8.8 1.3 2 0 0 2 2 2 1 Rhomboid family Ytp1 PF10355.9 EGE07097.1 - 2e-117 391.4 6.4 2e-117 391.4 6.4 1.8 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EGE07097.1 - 1.4e-28 98.8 8.3 1.4e-28 98.8 8.3 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) CcmD PF04995.14 EGE07097.1 - 0.19 11.8 1.0 14 5.9 0.2 3.5 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) RTA1 PF04479.13 EGE07098.1 - 2e-76 256.2 1.4 2.3e-76 256.0 1.4 1.0 1 0 0 1 1 1 1 RTA1 like protein Pex24p PF06398.11 EGE07098.1 - 0.11 11.4 0.1 0.3 10.0 0.1 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin SafA PF17073.5 EGE07098.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Two-component-system connector protein PhrC_PhrF PF11131.8 EGE07098.1 - 2.2 7.9 5.4 9.1 6.0 1.0 2.5 2 0 0 2 2 2 0 Rap-phr extracellular signalling Gaa1 PF04114.14 EGE07100.1 - 2.5e-180 600.8 6.0 3.1e-180 600.5 6.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 EGE07101.1 - 5.8e-10 39.6 0.1 1.3e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EGE07101.1 - 0.00026 20.5 0.1 0.00051 19.6 0.1 1.4 1 0 0 1 1 1 1 Rpn9 C-terminal helix Methyltransf_23 PF13489.6 EGE07102.1 - 2.8e-13 50.0 0.0 3.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07102.1 - 2.5e-12 46.8 0.0 3.2e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07102.1 - 3.1e-12 47.1 0.0 5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07102.1 - 6.8e-12 45.9 0.0 1.3e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07102.1 - 3e-11 43.8 0.0 1.1e-10 42.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE07102.1 - 4.2e-07 29.5 0.0 7.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EGE07102.1 - 0.029 14.0 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DREV PF05219.12 EGE07102.1 - 0.036 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.6 EGE07102.1 - 0.038 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GMC_oxred_N PF00732.19 EGE07103.1 - 4.3e-62 210.1 0.0 6e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGE07103.1 - 5.3e-36 124.3 0.0 8.2e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EGE07103.1 - 1.1e-07 31.8 0.1 0.0039 16.8 0.0 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE07103.1 - 5.4e-07 29.0 0.0 0.0095 15.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGE07103.1 - 0.0003 21.0 0.0 0.00098 19.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGE07103.1 - 0.00085 18.6 0.2 0.009 15.3 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EGE07103.1 - 0.0014 17.8 0.1 0.002 17.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EGE07103.1 - 0.034 13.4 0.1 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE07103.1 - 0.11 11.2 0.0 1.2 7.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EGE07103.1 - 0.17 12.5 0.1 37 5.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EXS PF03124.14 EGE07104.1 - 6.5e-86 288.7 34.0 7.9e-86 288.4 34.0 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGE07104.1 - 3.1e-29 103.1 11.8 3e-23 83.4 7.9 2.1 1 1 1 2 2 2 2 SPX domain HAD_2 PF13419.6 EGE07105.1 - 2.3e-16 60.4 0.0 3.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE07105.1 - 2.1e-09 38.0 0.0 1.2e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE07105.1 - 7.8e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1100 PF06500.11 EGE07106.1 - 8.2e-05 21.6 0.0 0.00017 20.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EGE07106.1 - 0.00024 21.8 0.0 0.00045 20.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGE07106.1 - 0.0024 17.4 0.0 0.0064 16.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGE07106.1 - 0.011 15.3 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 EGE07106.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EGE07106.1 - 0.047 13.0 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 EGE07107.1 - 1.8e-09 37.6 10.5 3.2e-09 36.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi_ubiq PF14452.6 EGE07107.1 - 0.095 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Multiubiquitin Abhydrolase_2 PF02230.16 EGE07108.1 - 8.3e-22 78.1 0.0 1.1e-21 77.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EGE07108.1 - 3.1e-06 28.0 0.2 3.8e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family XylR_N PF06505.11 EGE07108.1 - 0.029 14.1 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Activator of aromatic catabolism PDEase_I_N PF08499.12 EGE07109.1 - 0.031 14.1 0.3 0.5 10.2 0.1 2.5 1 1 1 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Metallophos PF00149.28 EGE07110.1 - 2.9e-37 129.1 0.6 7.3e-37 127.9 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EGE07110.1 - 0.11 12.2 0.6 1.7 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) HSP70 PF00012.20 EGE07112.1 - 1.8e-13 49.6 0.0 2.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGE07112.1 - 4.1e-06 25.8 0.1 0.0041 16.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein EFG_C PF00679.24 EGE07113.1 - 0.062 13.3 0.3 3.6 7.7 0.1 2.4 1 1 1 2 2 2 0 Elongation factor G C-terminus Tup_N PF08581.10 EGE07113.1 - 0.38 11.1 1.7 1.7 9.0 0.6 2.2 2 0 0 2 2 2 0 Tup N-terminal Voldacs PF03517.13 EGE07114.1 - 3.4e-31 108.2 1.3 3.4e-31 108.2 1.3 2.3 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling LIP PF03583.14 EGE07116.1 - 1.9e-69 234.1 0.0 2.6e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase RdRP PF05183.12 EGE07120.1 - 1.3e-116 390.7 0.0 4e-116 389.0 0.0 1.7 1 1 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 EGE07121.1 - 1e-126 423.4 41.3 1.2e-126 423.1 41.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE07121.1 - 2.1e-36 125.7 41.1 2.6e-36 125.4 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Gtr1_RagA PF04670.12 EGE07124.1 - 3.3e-92 308.0 0.1 4e-92 307.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EGE07124.1 - 4.8e-08 33.2 0.0 8.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE07124.1 - 7.9e-08 31.9 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGE07124.1 - 3.1e-07 30.1 0.0 4.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGE07124.1 - 3.7e-07 30.2 0.0 7.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGE07124.1 - 0.012 14.9 2.9 1.7 7.7 1.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 EGE07124.1 - 0.013 14.7 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EGE07124.1 - 0.015 15.0 0.9 0.042 13.6 0.3 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGE07124.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EGE07124.1 - 0.074 12.9 0.4 0.42 10.5 0.1 2.3 3 1 1 4 4 4 0 RsgA GTPase AAA_7 PF12775.7 EGE07124.1 - 0.094 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 EGE07124.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AIG1 PF04548.16 EGE07124.1 - 0.33 10.2 1.0 0.5 9.7 0.4 1.9 2 1 0 2 2 2 0 AIG1 family zf-RanBP PF00641.18 EGE07126.1 - 1.9e-19 68.6 8.4 7.1e-10 38.0 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 EGE07126.1 - 2.8e-07 31.2 0.0 4.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_1 PF00076.22 EGE07126.1 - 7.9e-07 28.8 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd3 PF12719.7 EGE07127.1 - 1.2e-90 303.7 0.1 1.8e-89 299.8 0.0 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGE07127.1 - 4.5e-09 36.6 4.3 5e-05 23.6 0.3 4.4 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EGE07127.1 - 5.2e-07 30.0 2.6 0.38 11.3 0.1 5.4 4 1 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EGE07127.1 - 6.2e-06 26.0 6.7 0.24 11.8 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EGE07127.1 - 0.0025 17.9 0.1 0.11 12.5 0.0 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EGE07127.1 - 0.044 13.4 0.1 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RICTOR_N PF14664.6 EGE07127.1 - 0.059 12.4 0.6 1.7 7.6 0.1 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term PALP PF00291.25 EGE07128.1 - 7.9e-68 229.0 0.2 9.6e-68 228.7 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Oxidored_molyb PF00174.19 EGE07129.1 - 1.2e-59 200.8 0.0 1.7e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGE07129.1 - 1.1e-25 90.2 0.8 2.3e-25 89.2 0.8 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 EGE07129.1 - 0.24 11.6 2.3 0.56 10.4 0.2 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat Tim17 PF02466.19 EGE07130.1 - 8.3e-37 126.0 8.7 1.3e-36 125.3 8.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.6 EGE07131.1 - 2.3e-80 270.1 20.7 2.3e-80 270.1 20.7 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) SLATT_1 PF18181.1 EGE07131.1 - 0.097 12.6 0.7 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Bap31_Bap29_C PF18035.1 EGE07131.1 - 0.17 11.9 3.2 0.35 10.9 3.2 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain CAP59_mtransfer PF11735.8 EGE07132.1 - 1.5e-71 240.9 0.0 1.9e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Cobalamin_bind PF01122.19 EGE07136.1 - 0.095 11.6 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein Phage_terminase PF10668.9 EGE07137.1 - 0.063 13.3 0.8 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Phage terminase small subunit Pkinase PF00069.25 EGE07138.1 - 2.3e-70 237.0 0.0 3.1e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07138.1 - 1.2e-47 162.4 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE07138.1 - 1.2e-05 24.4 0.0 3.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGE07138.1 - 0.00016 21.1 0.0 0.0032 16.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGE07138.1 - 0.029 14.3 0.1 6.5 6.6 0.0 2.9 3 1 1 4 4 4 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGE07138.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 ABC1 family FAD-oxidase_C PF02913.19 EGE07139.1 - 6e-63 212.8 0.0 8.6e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGE07139.1 - 9.8e-36 122.5 0.4 1.9e-35 121.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.26 EGE07140.1 - 6e-16 58.5 0.3 3.8e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGE07140.1 - 9.6e-13 47.6 0.1 1.5e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EGE07140.1 - 0.048 13.6 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 EGE07141.1 - 4.8e-11 43.0 16.0 8.7e-11 42.2 16.0 1.4 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_9 PF14369.6 EGE07141.1 - 0.11 12.8 7.5 1.6 9.1 7.0 2.5 1 1 1 2 2 2 0 zinc-ribbon Zn-ribbon_8 PF09723.10 EGE07141.1 - 2 8.6 13.7 5.5 7.2 6.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 EGE07141.1 - 4.8 7.5 16.8 67 3.8 7.9 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 EGE07141.1 - 5.7 6.9 13.9 2.9 7.9 0.1 3.2 3 1 0 3 3 3 0 zinc-ribbon domain ERG4_ERG24 PF01222.17 EGE07142.1 - 7.3e-148 492.9 9.8 8.3e-148 492.7 9.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGE07142.1 - 6.1e-05 22.7 0.1 0.00019 21.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) BBS2_Mid PF14783.6 EGE07143.1 - 0.2 11.7 0.1 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EGE07143.1 - 4.1 8.0 8.9 3.5 8.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain FMO-like PF00743.19 EGE07144.1 - 5.3e-18 64.7 0.3 4.6e-16 58.3 0.1 3.0 2 1 1 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGE07144.1 - 8.1e-05 22.0 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07144.1 - 0.00011 21.4 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGE07144.1 - 0.00015 21.9 0.3 0.00057 20.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGE07144.1 - 0.0029 16.9 0.2 0.058 12.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GCR1_C PF12550.8 EGE07144.1 - 0.063 13.6 1.6 0.34 11.3 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes APH PF01636.23 EGE07145.1 - 2.8e-19 70.0 0.0 4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE07145.1 - 4e-06 26.6 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EGE07145.1 - 0.004 16.4 0.1 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase RIO1 PF01163.22 EGE07145.1 - 0.0095 15.5 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 EGE07145.1 - 0.017 14.5 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.20 EGE07145.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EGE07145.1 - 0.09 11.6 0.0 0.17 10.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) UPF0047 PF01894.17 EGE07147.1 - 3.2e-38 130.4 0.0 3.6e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 GFA PF04828.14 EGE07148.1 - 5.4e-05 23.4 3.2 0.00085 19.6 3.2 2.3 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ECH_1 PF00378.20 EGE07149.1 - 3.9e-23 82.1 0.0 1.3e-21 77.1 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE07149.1 - 0.013 15.0 0.1 0.041 13.4 0.1 1.9 2 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase LPD15 PF18828.1 EGE07149.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 zf-CHCC PF10276.9 EGE07150.1 - 1.4e-15 57.0 2.1 2.3e-15 56.3 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain MPP6 PF10175.9 EGE07151.1 - 9.8e-06 26.1 9.5 0.00032 21.2 9.5 2.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Dscam_C PF12355.8 EGE07151.1 - 0.2 12.6 0.3 0.2 12.6 0.3 2.6 1 1 1 3 3 3 0 Down syndrome cell adhesion molecule C terminal SUZ PF12752.7 EGE07151.1 - 8 7.3 11.7 1.2 10.0 4.3 2.8 2 1 0 2 2 2 0 SUZ domain CoaE PF01121.20 EGE07152.1 - 1.8e-42 145.0 0.0 2.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGE07152.1 - 0.011 16.3 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain 2TM PF13239.6 EGE07152.1 - 0.035 14.4 0.1 0.035 14.4 0.1 1.6 2 0 0 2 2 2 0 2TM domain NUDIX_2 PF13869.6 EGE07153.1 - 8.2e-61 204.9 0.0 5.4e-46 156.6 0.0 2.0 1 1 1 2 2 2 2 Nucleotide hydrolase APH PF01636.23 EGE07154.1 - 3.2e-14 53.4 0.0 5.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE07154.1 - 0.13 11.9 0.2 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M16_M PF16187.5 EGE07155.1 - 1.7e-98 329.4 0.1 2.5e-98 328.8 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGE07155.1 - 1.3e-35 123.1 0.2 5.1e-23 82.0 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGE07155.1 - 1e-32 113.2 2.2 5.9e-22 78.2 0.4 3.7 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) DUF386 PF04074.12 EGE07156.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 YhcH/YjgK/YiaL DUF1258 PF06869.12 EGE07157.1 - 0.21 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) MFS_1 PF07690.16 EGE07158.1 - 2.2e-33 115.6 38.8 2.2e-33 115.6 38.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily YesK PF14150.6 EGE07158.1 - 0.33 11.2 0.2 0.33 11.2 0.2 4.1 5 0 0 5 5 5 0 YesK-like protein TraL PF07178.11 EGE07158.1 - 2 8.9 0.0 2 8.9 0.0 4.3 4 1 1 6 6 6 0 TraL protein Sugar_tr PF00083.24 EGE07160.1 - 5.3e-114 381.6 23.9 4.7e-113 378.4 23.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE07160.1 - 6.5e-18 64.8 44.4 8.6e-12 44.6 23.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGE07160.1 - 0.0052 15.3 6.0 0.021 13.3 0.8 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Arb2 PF09757.9 EGE07161.1 - 1.5e-97 325.7 5.4 2.2e-97 325.2 5.4 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EGE07161.1 - 2.3e-86 290.0 0.1 1.9e-85 287.1 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylase domain DUF1957 PF09210.11 EGE07161.1 - 0.095 13.1 0.1 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1957) Gp_dh_C PF02800.20 EGE07162.1 - 4.4e-71 237.6 0.0 6.4e-71 237.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGE07162.1 - 1.3e-38 131.4 0.2 3.3e-38 130.1 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGE07162.1 - 0.003 17.7 0.0 0.011 15.9 0.0 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EGE07162.1 - 0.077 12.4 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGE07162.1 - 0.088 13.6 0.0 6.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pho88 PF10032.9 EGE07165.1 - 5.5e-71 237.6 0.3 6.1e-71 237.4 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 EGE07165.1 - 0.059 14.1 0.3 0.25 12.2 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Histone PF00125.24 EGE07166.1 - 8.2e-16 58.6 0.0 1e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGE07166.1 - 5.7e-12 45.2 0.0 9.3e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGE07166.1 - 0.00026 21.2 0.0 0.00037 20.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSF_DNA-bind PF00447.17 EGE07168.1 - 2.4e-29 101.8 0.3 5.3e-29 100.7 0.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EGE07168.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Ets-domain TMF_DNA_bd PF12329.8 EGE07168.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RRM_1 PF00076.22 EGE07172.1 - 8.8e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAS_C PF12026.8 EGE07172.1 - 0.17 11.9 1.5 0.26 11.4 1.5 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Pro_isomerase PF00160.21 EGE07173.1 - 1.4e-37 129.4 0.0 2.7e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC_WH_C PF18137.1 EGE07173.1 - 0.029 14.5 0.7 0.029 14.5 0.7 2.8 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal His_Phos_2 PF00328.22 EGE07174.1 - 7.8e-09 35.4 0.0 2.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_M19 PF01244.21 EGE07175.1 - 2.6e-109 365.2 0.0 3e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) AAA PF00004.29 EGE07176.1 - 1.6e-16 60.9 0.3 3.1e-16 60.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGE07176.1 - 1e-15 57.9 0.0 4.4e-15 55.9 0.0 2.2 3 0 0 3 3 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGE07176.1 - 1.8e-12 47.4 0.0 8.8e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGE07176.1 - 7.9e-09 35.7 0.0 1.4e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGE07176.1 - 3.1e-08 33.8 0.0 1.8e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA_30 PF13604.6 EGE07176.1 - 1.4e-06 28.1 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE07176.1 - 3.6e-06 27.5 0.0 5.2e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EGE07176.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 EGE07176.1 - 5.2e-06 26.4 0.0 9.5e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGE07176.1 - 1.5e-05 25.0 0.2 6.2e-05 23.0 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE07176.1 - 1.7e-05 25.1 0.3 0.00015 22.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGE07176.1 - 9.6e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGE07176.1 - 0.00012 21.8 0.0 0.00033 20.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGE07176.1 - 0.00028 20.7 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGE07176.1 - 0.00028 20.8 0.0 0.00095 19.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGE07176.1 - 0.00083 19.4 0.0 0.086 12.8 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGE07176.1 - 0.00097 19.5 0.0 0.0024 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGE07176.1 - 0.001 19.1 0.0 0.0028 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGE07176.1 - 0.0024 17.6 0.0 0.0063 16.2 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain PhoH PF02562.16 EGE07176.1 - 0.0031 17.0 0.2 0.61 9.5 0.0 2.3 1 1 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EGE07176.1 - 0.0064 16.3 0.0 0.036 13.9 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 EGE07176.1 - 0.0077 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGE07176.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGE07176.1 - 0.024 14.0 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGE07176.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGE07176.1 - 0.05 13.0 0.2 0.26 10.6 0.1 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EGE07176.1 - 0.057 12.6 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EGE07176.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain MiaE PF06175.11 EGE07176.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RNA_helicase PF00910.22 EGE07176.1 - 0.069 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGE07176.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Cullin_Nedd8 PF10557.9 EGE07176.1 - 0.11 12.5 0.3 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Cullin protein neddylation domain P21-Arc PF04062.14 EGE07177.1 - 2.2e-75 252.5 0.0 2.5e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.18 EGE07177.1 - 0.066 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide NmrA PF05368.13 EGE07178.1 - 8.9e-17 61.4 0.3 1.2e-16 61.0 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGE07178.1 - 2e-16 60.4 0.1 3.1e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGE07178.1 - 1.3e-06 28.1 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGE07178.1 - 1.8e-06 28.1 0.2 3.4e-06 27.2 0.2 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EGE07178.1 - 1.6e-05 25.4 0.0 3.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGE07178.1 - 8.7e-05 21.7 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EGE07178.1 - 0.00048 20.4 0.5 0.0011 19.2 0.5 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 EGE07178.1 - 0.0013 18.4 0.0 0.0029 17.3 0.1 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EGE07178.1 - 0.003 17.6 0.4 0.0046 17.0 0.4 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 EGE07178.1 - 0.0035 16.5 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EGE07178.1 - 0.013 14.6 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Gp_dh_N PF00044.24 EGE07178.1 - 0.043 14.1 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EGE07178.1 - 0.048 12.8 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGE07178.1 - 0.051 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EGE07178.1 - 0.053 13.4 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 EGE07178.1 - 0.06 14.2 0.5 0.12 13.2 0.2 1.7 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.19 EGE07178.1 - 0.18 12.5 0.8 0.88 10.3 1.1 2.0 2 0 0 2 2 1 0 CoA binding domain Pkinase PF00069.25 EGE07179.1 - 8.5e-10 38.4 0.0 2.3e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 EGE07180.1 - 6.5e-12 45.9 0.0 2.4e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE07180.1 - 0.00024 20.5 0.1 0.59 9.4 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGE07181.1 - 3.9e-12 46.1 0.0 6.7e-11 42.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07181.1 - 5.2e-06 25.9 0.0 0.00022 20.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE07181.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M35 PF02102.15 EGE07182.1 - 4.1e-102 341.7 14.7 4.6e-102 341.6 14.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGE07182.1 - 2.9e-41 141.4 3.4 2.9e-41 141.4 3.4 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGE07182.1 - 0.0032 17.1 3.7 0.011 15.3 3.7 1.8 1 1 0 1 1 1 1 Putative peptidase family DUF468 PF04318.12 EGE07183.1 - 0.025 15.3 0.1 0.057 14.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF468) NatB_MDM20 PF09797.9 EGE07187.1 - 0.06 12.3 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Ku PF02735.16 EGE07188.1 - 1.3e-44 152.3 0.0 3.2e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGE07188.1 - 8.7e-32 110.6 0.0 1.3e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGE07188.1 - 2.5e-22 79.4 6.9 2.3e-19 69.9 2.2 2.8 1 1 1 2 2 2 2 Ku70/Ku80 C-terminal arm SAP PF02037.27 EGE07188.1 - 1.8e-13 49.9 0.0 3.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EGE07188.1 - 0.00081 19.1 0.2 0.00081 19.1 0.2 1.8 2 0 0 2 2 2 1 HeH/LEM domain Ferrochelatase PF00762.19 EGE07189.1 - 8e-98 327.4 0.0 9.4e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.16 EGE07190.1 - 1.4e-29 103.2 16.7 1.4e-21 76.9 8.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE07190.1 - 0.0017 16.7 8.8 0.37 9.0 3.8 2.9 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF2269 PF10027.9 EGE07190.1 - 0.028 14.5 0.3 0.028 14.5 0.3 2.8 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) FA_desaturase PF00487.24 EGE07190.1 - 2.6 7.8 9.9 0.49 10.2 2.2 3.1 3 1 1 4 4 4 0 Fatty acid desaturase PPR PF01535.20 EGE07191.1 - 1.3e-06 28.2 0.4 0.07 13.4 0.0 5.3 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 EGE07191.1 - 0.0069 16.6 0.0 1.9 8.7 0.0 4.0 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.7 EGE07191.1 - 0.011 15.5 0.0 10 6.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat TPR_14 PF13428.6 EGE07191.1 - 0.011 16.4 0.5 2.1 9.4 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE07191.1 - 0.022 15.3 0.1 11 6.6 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat SE PF08491.10 EGE07192.1 - 1.6e-93 312.8 0.0 1.9e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGE07192.1 - 5.3e-10 39.1 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGE07192.1 - 5.6e-09 36.0 0.4 7.2e-06 25.8 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE07192.1 - 3.2e-06 26.5 2.0 7.5e-05 22.0 2.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EGE07192.1 - 0.00015 21.1 0.1 0.00034 20.0 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE07192.1 - 0.00034 20.8 0.8 0.00072 19.7 0.8 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EGE07192.1 - 0.00038 19.9 1.6 0.00051 19.5 1.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EGE07192.1 - 0.00042 19.5 0.2 0.0011 18.2 0.1 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EGE07192.1 - 0.00046 19.4 0.6 0.00088 18.4 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EGE07192.1 - 0.0013 17.5 0.3 0.0033 16.2 0.3 1.6 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGE07192.1 - 0.0018 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGE07192.1 - 0.0021 18.6 0.1 0.021 15.4 0.2 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EGE07192.1 - 0.0092 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EGE07192.1 - 0.012 15.2 0.4 0.04 13.6 0.4 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EGE07192.1 - 0.024 13.5 0.2 0.39 9.5 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGE07192.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EGE07192.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 EGE07192.1 - 0.18 11.0 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PAP_assoc PF03828.19 EGE07193.1 - 4.2e-17 62.1 0.1 9.9e-17 60.9 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGE07193.1 - 2.4e-06 27.8 0.0 4.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGE07193.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Dicty_REP PF05086.12 EGE07194.1 - 0.016 13.2 4.7 0.02 12.9 4.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 EGE07194.1 - 0.021 14.8 11.8 0.034 14.1 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGE07194.1 - 5 5.2 16.0 6.3 4.9 16.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 COQ7 PF03232.13 EGE07195.1 - 0.004 16.9 0.2 0.0055 16.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Utp21 PF04192.12 EGE07195.1 - 0.01 15.3 0.6 0.017 14.7 0.6 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Peptidase_S49_N PF08496.10 EGE07195.1 - 3.2 7.8 8.0 5.1 7.1 8.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rib_recp_KP_reg PF05104.12 EGE07195.1 - 6.1 7.9 13.5 8.8 7.4 13.5 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Tho2 PF11262.8 EGE07195.1 - 7.6 5.6 10.5 10 5.2 10.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SLC35F PF06027.12 EGE07197.1 - 2.2e-98 329.5 22.2 2.6e-98 329.2 22.2 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EGE07197.1 - 2.6e-10 39.8 0.8 4e-10 39.2 0.8 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGE07197.1 - 3.7e-10 40.1 38.2 1.3e-05 25.3 15.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EGE07197.1 - 4 6.4 11.0 0.026 13.6 1.2 2.3 3 1 0 3 3 3 0 FUSC-like inner membrane protein yccS SMK-1 PF04802.15 EGE07198.1 - 3.3e-76 255.4 0.3 6e-76 254.5 0.3 1.4 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF572 PF04502.13 EGE07198.1 - 0.67 9.5 5.8 1.1 8.9 5.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) LIDHydrolase PF10230.9 EGE07199.1 - 1.6e-71 241.0 0.0 1.9e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGE07199.1 - 4.2e-05 22.9 0.1 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE07199.1 - 0.016 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EGE07199.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 EGE07199.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGE07199.1 - 0.091 12.6 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EGE07199.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3530 PF12048.8 EGE07199.1 - 0.16 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DCP1 PF06058.13 EGE07200.1 - 1.7e-28 98.9 0.0 2.6e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DUF1299 PF06975.11 EGE07200.1 - 0.0093 16.0 0.5 0.018 15.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1299) Exo_endo_phos PF03372.23 EGE07201.1 - 1.2e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 EGE07201.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 RhoGAP domain DUF4680 PF15730.5 EGE07201.1 - 0.52 10.7 1.8 1.2 9.4 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Fib_alpha PF08702.10 EGE07202.1 - 0.45 10.7 2.6 0.86 9.8 2.6 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family STE3 PF02076.15 EGE07203.1 - 5.8e-92 308.0 17.0 7.2e-92 307.7 17.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4131 PF13567.6 EGE07203.1 - 0.47 10.1 3.6 0.34 10.5 0.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) FeoB_associated PF12669.7 EGE07203.1 - 0.59 10.6 0.1 0.59 10.6 0.1 2.6 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Pex24p PF06398.11 EGE07203.1 - 1.1 8.1 8.6 0.057 12.4 3.2 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin BPD_transp_1 PF00528.22 EGE07203.1 - 3.1 7.5 8.2 3.3 7.4 5.6 2.2 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component SSB PF00436.25 EGE07204.1 - 5.9e-14 52.0 0.0 7.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family EFG_II PF14492.6 EGE07204.1 - 0.19 11.8 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II HA2 PF04408.23 EGE07205.1 - 2.1e-14 53.7 0.0 6.9e-13 48.8 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGE07205.1 - 3.8e-07 30.4 0.0 1.1e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGE07205.1 - 0.0039 17.5 0.1 0.0095 16.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGE07205.1 - 0.013 15.2 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE07205.1 - 0.02 15.2 0.0 0.089 13.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 EGE07205.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein ABC1 PF03109.16 EGE07206.1 - 8.3e-21 74.4 0.0 2.9e-18 66.2 0.0 2.5 1 1 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGE07206.1 - 0.042 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Raf1_HTH PF18579.1 EGE07206.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain SLAC1 PF03595.17 EGE07207.1 - 4.6e-84 282.4 52.6 5.4e-84 282.2 52.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TraP PF07296.11 EGE07207.1 - 0.47 9.6 1.9 0.52 9.5 0.3 1.8 2 0 0 2 2 2 0 TraP protein CAAD PF14159.6 EGE07207.1 - 2.5 8.0 6.5 0.41 10.5 0.3 2.8 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Peptidase_S8 PF00082.22 EGE07210.1 - 1.9e-24 86.5 14.1 3.3e-24 85.7 13.8 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE07210.1 - 7.5e-20 71.4 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beta-lactamase PF00144.24 EGE07211.1 - 1.6e-44 152.5 0.0 2.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EGE07211.1 - 0.0059 16.2 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EGE07211.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase adh_short PF00106.25 EGE07212.1 - 1.4e-40 138.9 0.0 1.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07212.1 - 7.6e-28 97.7 0.0 9.1e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGE07212.1 - 0.00019 20.9 0.0 0.0016 17.9 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGE07212.1 - 0.025 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N PF00107.26 EGE07212.1 - 0.089 12.8 0.2 0.25 11.3 0.1 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase ATP-grasp_2 PF08442.10 EGE07213.1 - 1.1e-72 243.8 0.5 2e-72 243.0 0.5 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGE07213.1 - 4e-25 88.4 0.7 1.7e-24 86.4 0.3 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EGE07213.1 - 2.2e-06 27.3 0.8 3.8e-06 26.5 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EGE07213.1 - 0.0041 16.9 1.4 0.8 9.4 0.1 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EGE07213.1 - 0.013 15.3 0.3 1.9 8.3 0.1 2.5 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain VID27_N PF17748.1 EGE07213.1 - 0.14 12.0 0.8 0.24 11.2 0.8 1.3 1 0 0 1 1 1 0 VID27 N-terminal region DUF3245 PF11595.8 EGE07214.1 - 1.7e-41 142.2 10.6 2.5e-41 141.6 10.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.17 EGE07216.1 - 2.6e-06 27.9 0.4 1.8e-05 25.3 0.1 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding RPN2_C PF18004.1 EGE07217.1 - 0.0045 16.9 6.4 0.0057 16.6 6.4 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EGE07217.1 - 0.062 11.6 5.3 0.056 11.7 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EGE07217.1 - 0.071 12.8 6.4 0.12 12.1 6.4 1.3 1 0 0 1 1 1 0 FAM176 family DUF3824 PF12868.7 EGE07217.1 - 0.087 13.5 8.3 0.15 12.7 8.3 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Afi1 PF07792.12 EGE07217.1 - 0.095 13.2 0.7 0.11 13.0 0.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 EGE07217.1 - 0.17 11.7 5.0 0.19 11.5 5.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myc_N PF01056.18 EGE07217.1 - 0.18 11.7 2.7 0.18 11.6 2.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region MCU PF04678.13 EGE07217.1 - 0.19 11.8 1.2 0.22 11.6 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Presenilin PF01080.17 EGE07217.1 - 0.25 10.1 2.2 0.25 10.1 2.2 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGE07217.1 - 0.25 11.1 3.8 0.33 10.7 3.8 1.1 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 EGE07217.1 - 0.26 11.3 4.0 0.39 10.8 4.0 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4770 PF15994.5 EGE07217.1 - 0.42 10.8 3.8 0.61 10.3 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Nucleo_P87 PF07267.11 EGE07217.1 - 0.6 8.9 8.6 0.62 8.9 8.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rrn6 PF10214.9 EGE07217.1 - 0.99 7.8 3.8 1 7.8 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TMEM51 PF15345.6 EGE07217.1 - 1.6 8.5 6.9 2.3 8.0 6.9 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5427 PF10310.9 EGE07217.1 - 1.7 7.5 8.8 1.9 7.3 8.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) MAP17 PF15807.5 EGE07217.1 - 1.8 8.8 6.7 2.6 8.3 6.7 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4228 PF14009.6 EGE07217.1 - 1.8 8.9 7.1 2.3 8.6 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF2828 PF11443.8 EGE07217.1 - 2 6.4 7.7 2.2 6.2 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Coilin_N PF15862.5 EGE07217.1 - 3.8 7.3 10.8 5.7 6.7 10.8 1.3 1 0 0 1 1 1 0 Coilin N-terminus WRNPLPNID PF15017.6 EGE07217.1 - 8.4 7.4 10.1 4.4 8.3 8.0 1.6 2 0 0 2 2 1 0 Putative WW-binding domain and destruction box NPR3 PF03666.13 EGE07217.1 - 9.4 4.9 6.8 11 4.7 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pribosyltran PF00156.27 EGE07219.1 - 1.1e-05 25.0 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 EGE07220.1 - 4.3e-33 113.4 0.2 4.7e-33 113.2 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Yip1 PF04893.17 EGE07220.1 - 0.083 12.6 2.2 0.11 12.2 2.2 1.0 1 0 0 1 1 1 0 Yip1 domain KAP PF05804.12 EGE07221.1 - 0.0035 15.5 0.0 0.022 12.9 0.0 1.9 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Oxidored-like PF09791.9 EGE07222.1 - 4.7e-24 83.8 4.0 1.1e-23 82.7 4.0 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 EGE07222.1 - 0.072 13.1 3.1 0.17 11.9 3.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) DUF4404 PF14357.6 EGE07223.1 - 0.92 10.2 5.7 4.6 7.9 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4635 PF15466.6 EGE07223.1 - 1.2 8.6 4.2 11 5.5 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Ribosomal_L13e PF01294.18 EGE07224.1 - 5e-78 261.1 2.5 7.4e-78 260.5 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e GrpE PF01025.19 EGE07225.1 - 0.031 14.0 6.7 1.4 8.6 0.3 2.3 2 0 0 2 2 2 0 GrpE TMF_TATA_bd PF12325.8 EGE07225.1 - 0.1 12.8 9.5 0.2 11.9 9.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mto2_bdg PF12808.7 EGE07225.1 - 0.21 11.9 6.9 0.095 13.0 1.7 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region LRR_8 PF13855.6 EGE07226.1 - 3.6e-30 103.5 35.3 2.2e-09 37.0 2.1 8.1 7 1 2 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EGE07226.1 - 5.7e-23 80.6 43.6 7e-06 26.3 0.3 10.0 6 4 5 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGE07226.1 - 7.2e-06 25.9 31.7 0.85 10.4 0.0 11.8 11 2 1 12 12 12 1 Leucine Rich Repeat LRR_9 PF14580.6 EGE07226.1 - 0.24 10.9 20.2 0.6 9.6 0.9 4.3 2 2 1 5 5 5 0 Leucine-rich repeat GCIP PF13324.6 EGE07227.1 - 2.4e-26 92.9 5.2 2.4e-26 92.9 5.2 1.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.13 EGE07227.1 - 0.0018 18.2 2.0 0.0027 17.6 2.0 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF5617 PF18493.1 EGE07227.1 - 0.021 14.9 0.1 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) PMC2NT PF08066.12 EGE07227.1 - 0.39 11.4 6.4 7.6 7.3 0.0 3.7 2 1 2 4 4 4 0 PMC2NT (NUC016) domain Actin PF00022.19 EGE07228.1 - 1.8e-103 346.3 0.0 1.5e-102 343.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGE07228.1 - 0.15 10.8 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein IBR PF01485.21 EGE07230.1 - 2.4e-05 24.4 35.2 7.8e-05 22.8 9.5 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ANAPC16 PF17256.2 EGE07230.1 - 1.2 9.6 3.8 18 5.8 0.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 3HCDH_N PF02737.18 EGE07231.1 - 7.1e-52 175.9 0.8 9.4e-52 175.5 0.8 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGE07231.1 - 4e-34 117.1 0.0 8.9e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGE07231.1 - 0.00014 22.1 0.4 0.00039 20.6 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EGE07231.1 - 0.00023 21.4 0.1 0.00037 20.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGE07231.1 - 0.00041 20.0 0.1 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGE07231.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EGE07231.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE07231.1 - 0.026 13.8 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EGE07231.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EGE07231.1 - 0.061 12.7 0.9 0.97 8.8 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGE07231.1 - 0.11 13.1 1.7 0.39 11.3 1.6 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 EGE07231.1 - 0.15 12.6 0.1 0.37 11.4 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase RsbU_N PF08673.10 EGE07231.1 - 0.2 11.8 0.1 0.41 10.8 0.1 1.5 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain TIMELESS PF04821.14 EGE07232.1 - 8.2e-85 284.4 0.9 3.2e-84 282.5 0.0 2.3 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 EGE07232.1 - 1.6e-41 143.1 2.0 1.6e-41 143.1 2.0 4.2 2 1 0 3 3 3 2 Timeless protein C terminal region PhzC-PhzF PF02567.16 EGE07233.1 - 4.6e-39 134.6 0.4 1.5e-38 132.9 0.4 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Tfb2 PF03849.14 EGE07235.1 - 9.2e-136 452.5 0.0 1.4e-135 451.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGE07235.1 - 5.7e-24 84.3 0.6 1.2e-23 83.3 0.6 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGE07235.1 - 9.6e-06 25.8 0.0 0.00012 22.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Transp_cyt_pur PF02133.15 EGE07236.1 - 2.8e-69 234.0 26.6 3.7e-69 233.6 24.1 1.9 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 4HBT PF03061.22 EGE07237.1 - 8.2e-15 54.9 0.1 1.4e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EGE07237.1 - 0.0074 16.4 0.0 0.01 15.9 0.0 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) PBECR2 PF18810.1 EGE07237.1 - 0.034 14.5 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 4HBT_3 PF13622.6 EGE07237.1 - 0.072 13.3 0.0 0.079 13.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Aquarius_N PF16399.5 EGE07238.1 - 0 1096.1 0.0 0 1095.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EGE07238.1 - 2.4e-25 89.4 0.0 4.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE07238.1 - 5.4e-23 82.1 0.0 1.2e-22 81.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGE07238.1 - 2.8e-07 30.4 0.0 8e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGE07238.1 - 1.2e-06 28.9 0.0 2.5e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGE07238.1 - 5.7e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EGE07238.1 - 0.00041 20.2 0.1 0.4 10.4 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EGE07238.1 - 0.00069 20.0 0.1 0.0037 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain UvrD-helicase PF00580.21 EGE07238.1 - 0.0019 17.8 0.1 0.0062 16.1 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DnaB_C PF03796.15 EGE07238.1 - 0.0025 17.2 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EGE07238.1 - 0.0028 18.1 0.0 0.01 16.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 EGE07238.1 - 0.0074 15.5 0.0 0.77 8.9 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase Adeno_IVa2 PF02456.15 EGE07238.1 - 0.016 14.0 0.0 0.045 12.5 0.0 1.7 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 EGE07238.1 - 0.021 14.1 0.8 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGE07238.1 - 0.023 15.0 0.6 0.24 11.7 0.2 2.6 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EGE07238.1 - 0.026 14.3 0.1 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EGE07238.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGE07238.1 - 0.073 13.1 0.0 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 EGE07238.1 - 0.082 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ATPase_2 PF01637.18 EGE07238.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea efThoc1 PF11957.8 EGE07239.1 - 3.2e-155 517.5 7.4 4.1e-155 517.2 7.4 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RHH_1 PF01402.21 EGE07240.1 - 0.073 13.0 0.2 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Homeodomain PF00046.29 EGE07242.1 - 1.2e-16 60.3 3.4 2.3e-16 59.4 3.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGE07242.1 - 0.069 13.1 0.8 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Homeobox KN domain Adaptin_N PF01602.20 EGE07244.1 - 1.1e-124 416.9 4.8 1.4e-124 416.6 4.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGE07244.1 - 3.8e-41 139.8 0.0 8.7e-41 138.7 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGE07244.1 - 9.2e-17 61.4 0.0 3.1e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGE07244.1 - 0.0016 18.5 0.7 0.063 13.3 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EGE07244.1 - 0.0081 15.9 0.0 0.63 9.8 0.0 3.1 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.6 EGE07244.1 - 3.8 7.9 4.8 19 5.7 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ala_racemase_N PF01168.20 EGE07245.1 - 2.5e-21 76.3 0.0 3.4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain ERM PF00769.19 EGE07247.1 - 0.00027 20.8 16.4 0.00045 20.1 16.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Pkinase PF00069.25 EGE07247.1 - 0.00075 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGE07247.1 - 0.0042 17.0 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE07247.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EGE07247.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2828 PF11443.8 EGE07247.1 - 0.85 7.6 4.7 1.2 7.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Metallophos PF00149.28 EGE07248.1 - 3.9e-13 50.4 6.5 8e-13 49.4 6.5 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Acyltransferase PF01553.21 EGE07248.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Acyltransferase Glyco_hydro_18 PF00704.28 EGE07249.1 - 9.3e-63 212.8 0.1 1.5e-62 212.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Interferon PF00143.19 EGE07249.1 - 0.18 12.0 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain DND1_DSRM PF14709.7 EGE07252.1 - 0.0061 16.8 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsRBD2 PF17842.1 EGE07252.1 - 0.084 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 Fungal_trans PF04082.18 EGE07253.1 - 5.7e-17 61.6 0.1 1.7e-16 60.0 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE07253.1 - 1.1e-09 38.2 12.7 2.5e-09 37.1 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 EGE07253.1 - 0.4 11.1 2.1 0.97 9.8 2.1 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 EGE07253.1 - 7.1 6.2 9.8 12 5.5 9.8 1.2 1 0 0 1 1 1 0 Spt20 family TGT PF01702.18 EGE07254.1 - 7.2e-145 482.5 0.0 8.6e-145 482.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.19 EGE07255.1 - 4.3e-85 285.1 0.0 1.1e-57 195.2 0.0 2.0 1 1 1 2 2 2 2 Thymidylate synthase zf-AN1 PF01428.16 EGE07256.1 - 1.4e-24 86.0 25.8 2e-12 47.0 9.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EGE07256.1 - 0.04 14.2 25.8 0.042 14.1 9.4 3.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EGE07256.1 - 0.19 12.1 15.9 0.22 11.9 4.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Zn-ribbon_8 PF09723.10 EGE07256.1 - 3.8 7.7 10.7 2.3 8.4 2.7 2.8 2 0 0 2 2 2 0 Zinc ribbon domain C1_4 PF07975.12 EGE07256.1 - 6.9 7.0 18.7 2.5 8.4 7.3 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain Hist_deacetyl PF00850.19 EGE07257.1 - 1.4e-49 169.3 0.0 3.1e-49 168.1 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain R3H-assoc PF13902.6 EGE07258.1 - 2.7e-26 92.5 10.8 2.7e-26 92.5 10.8 1.7 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EGE07258.1 - 0.005 16.8 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 R3H domain DUF3584 PF12128.8 EGE07258.1 - 0.025 12.1 3.2 0.032 11.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LppA PF16708.5 EGE07258.1 - 0.081 12.8 0.9 0.41 10.6 0.6 2.1 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium STAT_int PF02865.17 EGE07258.1 - 0.13 12.7 1.2 0.24 11.9 1.0 1.6 1 1 0 1 1 1 0 STAT protein, protein interaction domain PIN_8 PF18476.1 EGE07258.1 - 0.24 11.2 3.8 0.34 10.7 3.8 1.2 1 0 0 1 1 1 0 PIN like domain Peptidase_M28 PF04389.17 EGE07259.1 - 3.3e-30 105.3 0.0 5.6e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGE07259.1 - 0.0004 20.1 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EGE07259.1 - 0.0016 18.0 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 2 Nicastrin DUF1774 PF08611.10 EGE07261.1 - 3.2e-30 104.3 1.7 3.2e-30 104.3 1.7 2.0 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) dCMP_cyt_deam_1 PF00383.23 EGE07262.1 - 3.2e-06 26.9 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Chitin_synth_1 PF01644.17 EGE07263.1 - 5.7e-77 257.3 0.0 8.8e-77 256.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EGE07263.1 - 2.5e-28 97.8 0.1 5.9e-28 96.6 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EGE07263.1 - 8.3e-23 80.8 0.2 5.4e-21 74.8 0.0 2.2 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGE07263.1 - 3.2e-07 30.5 0.3 7.5e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGE07263.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 AFG1_ATPase PF03969.16 EGE07264.1 - 0.0015 17.5 0.1 0.0023 16.9 0.1 1.3 1 0 0 1 1 1 1 AFG1-like ATPase PX PF00787.24 EGE07265.1 - 1.6e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 EGE07265.1 - 3.4e-12 45.8 0.3 2.2e-11 43.2 0.0 2.5 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 EGE07265.1 - 1.2e-06 28.3 0.6 3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 EGE07265.1 - 2.8e-06 27.1 0.3 5.8e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.17 EGE07265.1 - 0.014 15.0 0.5 0.029 14.1 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain IHABP4_N PF16174.5 EGE07265.1 - 0.25 11.9 0.1 0.25 11.9 0.1 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Pro-rich PF15240.6 EGE07265.1 - 3.3 8.0 31.6 0.45 10.8 4.1 2.2 2 0 0 2 2 2 0 Proline-rich Sec15 PF04091.12 EGE07266.1 - 7.4e-93 311.4 1.0 1e-92 310.9 0.0 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 EGE07266.1 - 0.044 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) CBFD_NFYB_HMF PF00808.23 EGE07267.1 - 5.6e-19 68.2 0.5 1e-18 67.3 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGE07267.1 - 5.3e-16 59.2 0.1 7.9e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EGE07267.1 - 0.043 14.1 0.0 0.077 13.3 0.0 1.4 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Totivirus_coat PF05518.11 EGE07267.1 - 0.093 10.8 4.8 0.11 10.5 4.8 1.1 1 0 0 1 1 1 0 Totivirus coat protein IceA2 PF05862.11 EGE07269.1 - 0.0032 17.3 0.2 0.096 12.6 0.1 2.3 2 0 0 2 2 2 1 Helicobacter pylori IceA2 protein PIG-S PF10510.9 EGE07269.1 - 0.11 11.3 0.3 0.87 8.3 0.1 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein PNP_UDP_1 PF01048.20 EGE07270.1 - 4.9e-46 156.9 0.3 4.3e-45 153.8 0.1 2.1 1 1 1 2 2 2 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 EGE07271.1 - 2.8e-28 98.0 0.0 4.7e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 EGE07272.1 - 7.3e-68 229.0 0.0 9.3e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) ECSCR PF15820.5 EGE07275.1 - 4.7 7.1 8.0 7 6.5 8.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator CDC50 PF03381.15 EGE07276.1 - 2.6e-83 279.8 0.0 4.3e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family FACT-Spt16_Nlob PF14826.6 EGE07277.1 - 4e-55 186.0 0.1 1.3e-54 184.4 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 EGE07277.1 - 9.8e-43 145.9 0.2 2.1e-42 144.8 0.2 1.6 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EGE07277.1 - 1.1e-26 93.8 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGE07277.1 - 2.2e-13 50.4 0.0 4.6e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CDC45 PF02724.14 EGE07277.1 - 0.0067 14.8 4.5 0.0095 14.3 4.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Mito_carr PF00153.27 EGE07278.1 - 8.8e-17 60.8 1.7 1.8e-10 40.6 0.0 3.3 3 1 0 3 3 3 2 Mitochondrial carrier protein GST_N_3 PF13417.6 EGE07280.1 - 8.6e-09 35.7 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE07280.1 - 6.7e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE07280.1 - 4.8e-05 23.5 0.0 8.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE07280.1 - 7.6e-05 22.7 0.1 0.00016 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE07280.1 - 0.00032 20.9 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.9 EGE07280.1 - 0.035 13.8 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Sugar_tr PF00083.24 EGE07281.1 - 9.1e-103 344.5 15.3 1.1e-102 344.3 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE07281.1 - 6.8e-32 110.8 21.1 1.8e-31 109.4 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGE07281.1 - 3.2e-10 39.2 14.4 1.4e-05 23.9 6.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGE07281.1 - 0.0041 16.0 3.2 0.52 9.1 0.0 2.3 2 0 0 2 2 2 2 MFS_1 like family INSIG PF07281.12 EGE07281.1 - 0.071 12.7 1.9 0.2 11.3 1.9 1.7 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) PMT PF02366.18 EGE07282.1 - 1.7e-88 296.4 14.6 1.7e-88 296.4 14.6 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EGE07282.1 - 1.7e-64 217.1 17.5 1.7e-64 217.1 17.5 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EGE07282.1 - 2.8e-35 121.9 0.1 4.5e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 MIR domain HKR_ArcB_TM PF18415.1 EGE07282.1 - 0.45 11.3 4.7 0.98 10.3 0.5 3.0 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Ras PF00071.22 EGE07285.1 - 1e-41 142.2 0.2 3.4e-36 124.3 0.0 3.1 3 0 0 3 3 3 3 Ras family Roc PF08477.13 EGE07285.1 - 1.2e-23 83.6 0.0 1.3e-17 64.1 0.0 3.4 3 0 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGE07285.1 - 4.4e-08 32.7 0.0 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.21 EGE07285.1 - 1.3e-07 31.2 0.1 3.1e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE07285.1 - 1.6e-07 31.1 0.0 2.9e-07 30.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE07285.1 - 0.0082 16.1 0.2 1.4 8.8 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGE07285.1 - 0.025 14.9 0.4 0.28 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain FAM176 PF14851.6 EGE07285.1 - 0.14 11.8 3.1 0.22 11.2 3.1 1.2 1 0 0 1 1 1 0 FAM176 family DUF2868 PF11067.8 EGE07285.1 - 0.17 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CAP_N PF01213.19 EGE07285.1 - 4 6.8 7.3 3.2 7.1 0.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Choline_transpo PF04515.12 EGE07287.1 - 1e-29 103.8 22.3 1e-29 103.8 22.3 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter Aldo_ket_red PF00248.21 EGE07290.1 - 3e-40 138.3 0.0 6.7e-39 133.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 EGE07291.1 - 2.7e-131 438.6 0.0 3.5e-131 438.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.23 EGE07293.1 - 2.2e-44 147.6 59.1 2.7e-09 36.7 2.0 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.6 EGE07293.1 - 2.7e-12 46.2 36.2 0.0067 16.1 0.7 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 EGE07293.1 - 1.1e-06 28.5 43.5 0.067 13.2 0.2 6.1 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 EGE07293.1 - 0.00091 18.9 38.6 0.69 9.7 0.9 6.5 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EGE07293.1 - 0.0027 17.5 42.1 0.052 13.4 1.0 6.5 4 2 3 7 7 7 5 Zinc knuckle F-box-like PF12937.7 EGE07294.1 - 8.9e-07 28.7 0.3 2e-06 27.6 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE07294.1 - 1.8e-06 27.7 0.2 3.4e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 F-box domain SAE2 PF08573.10 EGE07295.1 - 8.1e-29 101.0 3.5 5.3e-26 91.9 0.0 3.1 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus APG6_N PF17675.1 EGE07295.1 - 0.01 16.4 17.2 0.026 15.1 17.2 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region TMPIT PF07851.13 EGE07295.1 - 0.024 13.9 9.2 0.036 13.3 9.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin PF00804.25 EGE07295.1 - 0.026 14.2 7.7 0.066 12.9 7.7 1.7 1 0 0 1 1 1 0 Syntaxin EzrA PF06160.12 EGE07295.1 - 0.037 12.2 11.3 0.063 11.5 11.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA KASH_CCD PF14662.6 EGE07295.1 - 0.041 13.7 10.5 0.11 12.3 10.5 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EGE07295.1 - 0.061 11.5 14.2 0.097 10.8 14.2 1.2 1 0 0 1 1 1 0 HOOK protein Cnn_1N PF07989.11 EGE07295.1 - 0.42 10.8 12.3 20 5.4 10.7 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 SIKE PF05769.11 EGE07295.1 - 0.44 10.5 11.6 0.88 9.5 11.6 1.5 1 0 0 1 1 1 0 SIKE family ATG16 PF08614.11 EGE07295.1 - 0.76 10.0 15.6 0.089 13.0 10.4 2.1 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGE07295.1 - 0.97 9.2 8.3 0.68 9.7 5.8 2.0 1 1 0 1 1 1 0 Septum formation initiator DUF724 PF05266.14 EGE07295.1 - 1.2 9.0 11.7 2.3 8.0 11.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1640 PF07798.11 EGE07295.1 - 1.3 9.0 7.9 4.4 7.3 7.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 EGE07295.1 - 1.8 7.4 12.4 3 6.6 12.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EGE07295.1 - 1.8 7.8 5.2 3.3 7.0 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EGE07295.1 - 2.2 8.5 7.4 5 7.3 7.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EGE07295.1 - 2.6 5.8 4.6 3.8 5.3 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EGE07295.1 - 4.7 7.9 10.1 3.3 8.4 5.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 EGE07295.1 - 5.4 7.3 10.8 96 3.3 10.8 2.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 EGE07295.1 - 5.8 6.1 10.7 9.7 5.4 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pex16 PF08610.10 EGE07296.1 - 9.8e-141 468.6 0.1 1.1e-140 468.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 EGE07297.1 - 3.7e-45 154.2 0.0 2e-41 142.0 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII CENP-C_C PF11699.8 EGE07298.1 - 1.2e-33 115.1 1.5 1.2e-33 115.1 1.5 2.1 2 0 0 2 2 2 1 Mif2/CENP-C like Mif2_N PF15624.6 EGE07298.1 - 1.2e-20 74.5 12.2 1.2e-20 74.5 12.2 2.7 2 2 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EGE07298.1 - 2.4e-05 23.9 0.0 5.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Raftlin PF15250.6 EGE07298.1 - 3.3 6.3 10.4 0.2 10.4 4.8 1.7 2 0 0 2 2 2 0 Raftlin EBP50_C PF09007.11 EGE07298.1 - 3.8 8.5 12.9 1.5 9.8 9.3 2.0 2 0 0 2 2 2 0 EBP50, C-terminal CAP_GLY PF01302.25 EGE07299.1 - 1.1e-27 95.9 0.0 2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EGE07299.1 - 5.1e-16 58.9 0.0 1.1e-15 57.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 EGE07299.1 - 4.9e-06 26.2 0.0 1.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EGE07300.1 - 1.8e-12 47.7 0.0 2.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07300.1 - 6e-10 39.7 0.0 1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE07300.1 - 4.5e-07 29.9 0.0 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07300.1 - 2.3e-06 27.5 0.0 3.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07300.1 - 5e-05 24.0 0.0 9.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGE07300.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Myb_DNA-binding PF00249.31 EGE07302.1 - 5.2e-13 49.0 1.9 4.8e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE07302.1 - 6.2e-07 29.6 4.3 0.00074 19.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Spt20 PF12090.8 EGE07302.1 - 0.16 11.6 4.0 0.23 11.0 4.0 1.2 1 0 0 1 1 1 0 Spt20 family UCH PF00443.29 EGE07307.1 - 9e-29 100.7 0.1 1.1e-28 100.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07307.1 - 1e-17 64.7 3.7 6.6e-15 55.5 0.8 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGE07307.1 - 0.018 14.5 5.1 0.13 11.7 0.7 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase IL22 PF14565.6 EGE07307.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor MitMem_reg PF13012.6 EGE07309.1 - 3.2e-36 124.1 0.3 5.9e-36 123.3 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGE07309.1 - 1e-30 106.1 0.0 2.8e-30 104.7 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EGE07309.1 - 0.17 11.5 7.2 0.25 11.0 7.2 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 EGE07309.1 - 0.47 10.2 3.1 0.82 9.4 3.1 1.4 1 0 0 1 1 1 0 Connexin ADK PF00406.22 EGE07310.1 - 8e-61 204.6 0.1 1e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGE07310.1 - 4.7e-25 88.6 0.9 9.1e-25 87.7 0.3 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EGE07310.1 - 5.2e-17 61.5 0.0 1.3e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EGE07310.1 - 5.2e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGE07310.1 - 0.00026 21.5 0.0 0.00048 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGE07310.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase CFIA_Pcf11 PF11526.8 EGE07312.1 - 4.6e-12 46.2 1.4 2e-11 44.2 1.4 2.1 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EGE07312.1 - 1.7e-06 28.7 0.0 7.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EGE07312.1 - 0.0027 17.6 0.0 0.0088 15.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf_UBZ PF18439.1 EGE07312.1 - 1.2 8.8 8.0 4.6 6.9 1.4 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 EGE07312.1 - 2.2 9.3 3.9 39 5.5 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HOOK PF05622.12 EGE07313.1 - 2.1e-23 82.4 34.1 2.1e-23 82.4 34.1 2.8 2 1 1 3 3 3 1 HOOK protein KASH_CCD PF14662.6 EGE07313.1 - 0.053 13.3 67.5 0.14 11.9 16.3 5.1 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH Tn7_Tnp_TnsA_C PF08721.11 EGE07313.1 - 3.7 8.3 10.4 7.1 7.3 0.1 4.7 3 2 2 5 5 5 0 TnsA endonuclease C terminal Coprogen_oxidas PF01218.18 EGE07314.1 - 1.1e-135 451.1 0.0 1.4e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 EGE07315.1 - 3.1e-51 171.9 0.2 3.6e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGE07315.1 - 3.4e-06 27.4 0.0 4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_9 PF14604.6 EGE07315.1 - 0.15 11.9 0.0 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain NCE101 PF11654.8 EGE07316.1 - 1.8e-09 37.2 0.0 2.4e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Non-classical export protein 1 Mito_carr PF00153.27 EGE07318.1 - 2.6e-29 101.0 2.7 5.9e-15 55.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Apc15p PF05841.11 EGE07320.1 - 2.7e-12 47.6 0.1 8.5e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Apc15p protein Use1 PF09753.9 EGE07321.1 - 0.0048 16.7 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 CHZ PF09649.10 EGE07322.1 - 2.3e-13 49.4 0.1 2.3e-13 49.4 0.1 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ Shugoshin_C PF07557.11 EGE07322.1 - 0.19 11.6 0.1 0.28 11.0 0.1 1.2 1 0 0 1 1 1 0 Shugoshin C terminus CDC27 PF09507.10 EGE07322.1 - 0.45 9.8 9.8 0.48 9.7 9.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSP70 PF00012.20 EGE07323.1 - 5.5e-261 867.0 7.8 6.3e-261 866.8 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGE07323.1 - 1.8e-16 59.9 0.1 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGE07323.1 - 0.0032 17.2 0.0 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGE07323.1 - 0.012 16.0 4.1 5.4 7.5 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 EGE07323.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Fungal_trans PF04082.18 EGE07324.1 - 7.2e-22 77.7 0.4 1.1e-21 77.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE07324.1 - 0.013 15.6 13.4 0.023 14.8 13.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAX PF00292.18 EGE07324.1 - 0.019 14.9 0.6 0.18 11.7 1.0 2.0 2 0 0 2 2 2 0 'Paired box' domain DIOX_N PF14226.6 EGE07325.1 - 1.1e-31 110.0 0.1 2.4e-31 108.9 0.1 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE07325.1 - 2.3e-16 60.1 0.0 4.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 EGE07326.1 - 3e-63 214.1 16.9 3.9e-63 213.8 16.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF485 PF04341.12 EGE07326.1 - 4.7 7.2 8.8 7.7 6.5 0.2 3.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 GATase_2 PF00310.21 EGE07327.1 - 1.5e-180 600.4 0.0 2.2e-180 599.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EGE07327.1 - 2.4e-155 517.2 0.0 4.3e-155 516.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EGE07327.1 - 1.8e-114 382.0 0.0 5.6e-113 377.1 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EGE07327.1 - 1.3e-84 282.6 4.3 2.1e-84 281.9 4.3 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EGE07327.1 - 2.5e-25 89.3 0.1 1.5e-24 86.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EGE07327.1 - 4.3e-21 74.8 0.0 9.3e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EGE07327.1 - 1.8e-08 34.5 0.1 6.4e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE07327.1 - 7.8e-07 29.6 0.1 0.00061 20.3 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE07327.1 - 1.1e-06 28.6 1.7 0.0053 16.4 0.7 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGE07327.1 - 2.5e-06 27.1 0.2 4.7e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EGE07327.1 - 5.9e-06 25.7 0.9 0.041 13.1 0.1 3.4 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGE07327.1 - 1.5e-05 24.6 0.4 1.5e-05 24.6 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE07327.1 - 2.5e-05 23.5 1.1 0.00019 20.6 0.4 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGE07327.1 - 9.3e-05 21.3 0.4 9.3e-05 21.3 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EGE07327.1 - 0.00075 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGE07327.1 - 0.013 14.8 0.1 0.013 14.8 0.1 2.2 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 EGE07327.1 - 0.015 14.4 2.0 0.033 13.3 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGE07327.1 - 0.022 14.0 0.3 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 EGE07327.1 - 0.13 11.2 0.5 0.51 9.3 0.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_7 PF13241.6 EGE07327.1 - 0.16 12.4 1.3 14 6.2 0.1 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EGE07327.1 - 0.25 11.4 0.9 20 5.2 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 EGE07327.1 - 0.41 10.5 2.8 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Rossmann-like domain DUF3128 PF11326.8 EGE07328.1 - 5.1e-27 94.1 3.7 1e-26 93.1 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 EGE07329.1 - 9.9e-158 525.5 1.3 2.9e-156 520.6 1.3 2.2 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EGE07329.1 - 0.00053 20.0 0.1 0.0048 16.9 0.1 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EGE07329.1 - 0.0036 17.1 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EGE07329.1 - 0.0049 16.9 0.2 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) p450 PF00067.22 EGE07331.1 - 2.3e-06 26.6 0.0 0.0046 15.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Mcl1_mid PF12341.8 EGE07332.1 - 2.7e-104 348.7 0.0 6.3e-103 344.2 0.0 2.4 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EGE07332.1 - 2.7e-10 40.4 0.0 0.15 12.4 0.0 6.0 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE07332.1 - 5.8e-09 36.5 2.3 0.09 13.7 0.0 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat DNA_pol_alpha_N PF12254.8 EGE07332.1 - 0.016 15.3 3.2 0.047 13.8 3.2 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 EGE07332.1 - 0.088 11.4 0.0 0.17 10.5 0.0 1.5 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Frtz PF11768.8 EGE07332.1 - 0.13 10.5 0.0 4.1 5.6 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EGE07332.1 - 0.49 8.3 2.3 9.3 4.1 0.1 3.0 3 1 0 3 3 3 0 IKI3 family MMU163 PF17119.5 EGE07333.1 - 5.5e-114 379.5 0.0 6.9e-114 379.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis MFS_1 PF07690.16 EGE07334.1 - 1.6e-36 126.0 20.5 1.6e-36 126.0 20.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE07334.1 - 1.7e-07 30.5 5.8 3.3e-07 29.5 5.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EGE07334.1 - 0.00092 18.2 1.5 0.0016 17.5 1.5 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM LacY_symp PF01306.19 EGE07334.1 - 0.012 14.4 0.3 0.025 13.4 0.3 1.4 1 0 0 1 1 1 0 LacY proton/sugar symporter DUF1129 PF06570.11 EGE07334.1 - 0.48 9.9 2.7 16 4.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Herpes_UL7 PF01677.16 EGE07335.1 - 0.088 12.5 0.3 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like DUF1451 PF07295.11 EGE07335.1 - 0.15 12.1 2.4 0.41 10.7 2.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2347 PF09804.9 EGE07335.1 - 0.22 11.1 2.2 0.36 10.4 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) FAM76 PF16046.5 EGE07335.1 - 2.2 7.6 11.3 3.2 7.0 11.3 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4298 PF14131.6 EGE07335.1 - 2.5 8.1 9.5 0.63 10.0 4.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) CENP-W PF15510.6 EGE07336.1 - 3.7e-05 23.8 0.1 3.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 EGE07336.1 - 0.00081 19.6 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VTC PF09359.10 EGE07337.1 - 4e-83 279.0 0.1 7.9e-83 278.0 0.1 1.5 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EGE07337.1 - 1e-11 45.1 1.9 1e-11 45.1 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EGE07337.1 - 4.1e-08 33.6 21.7 3.1e-07 30.7 0.0 4.2 2 2 2 4 4 4 2 SPX domain RAP1 PF07218.11 EGE07337.1 - 0.1 10.9 0.1 0.18 10.1 0.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cation_efflux PF01545.21 EGE07337.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Cation efflux family 6PF2K PF01591.18 EGE07338.1 - 3.4e-67 226.0 0.0 8.2e-45 152.8 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGE07338.1 - 7.5e-29 100.8 0.0 4.6e-22 78.7 0.0 2.9 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGE07338.1 - 0.00016 21.8 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 EGE07338.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF202 PF02656.15 EGE07340.1 - 0.00088 19.7 7.9 0.0061 17.0 7.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Myelin_PLP PF01275.19 EGE07340.1 - 0.043 13.7 0.9 0.053 13.4 0.9 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) DUF2688 PF10892.8 EGE07341.1 - 0.18 11.3 2.3 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) FMN_dh PF01070.18 EGE07342.1 - 5.7e-104 347.9 0.0 6.6e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGE07342.1 - 3.4e-07 29.6 0.2 0.0004 19.5 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGE07342.1 - 5.2e-06 25.8 0.0 8.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EGE07342.1 - 0.017 14.5 0.4 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.21 EGE07342.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EGE07342.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Sec3_C_2 PF15278.6 EGE07342.1 - 0.2 12.0 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Cauli_VI PF01693.16 EGE07343.1 - 1.3e-38 131.0 7.8 4.8e-20 71.6 0.6 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EGE07343.1 - 7.7e-37 126.6 0.1 1.3e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EGE07343.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like YmgB PF10798.8 EGE07343.1 - 0.043 13.6 0.3 0.09 12.6 0.3 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Na_H_Exchanger PF00999.21 EGE07345.1 - 6.9e-48 163.3 20.1 8.9e-48 163.0 20.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.9 EGE07345.1 - 0.031 13.7 2.4 0.029 13.7 0.9 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv GFO_IDH_MocA PF01408.22 EGE07346.1 - 1.1e-13 52.0 0.0 1.9e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_23 PF13489.6 EGE07348.1 - 2.4e-17 63.3 0.0 3.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07348.1 - 4.8e-09 36.8 0.0 1.1e-08 35.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07348.1 - 4.9e-09 36.1 0.0 5.7e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07348.1 - 4.9e-08 33.6 0.0 2.6e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07348.1 - 2.3e-05 25.0 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EGE07348.1 - 0.0043 17.2 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EGE07348.1 - 0.0073 15.9 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EGE07348.1 - 0.0085 15.6 0.0 0.057 12.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 EGE07348.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase UPF0146 PF03686.13 EGE07348.1 - 0.015 15.2 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) CMAS PF02353.20 EGE07348.1 - 0.095 12.0 0.0 0.5 9.6 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGE07348.1 - 0.12 11.7 0.0 0.65 9.3 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ERG4_ERG24 PF01222.17 EGE07349.1 - 3.5e-143 477.5 21.8 4.1e-143 477.2 21.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ORC6 PF05460.13 EGE07349.1 - 1.8 7.7 6.7 3.3 6.9 6.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2052 PF09747.9 EGE07349.1 - 1.9 8.6 5.8 2.9 8.0 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-C3HC4 PF00097.25 EGE07350.1 - 1.1e-05 25.2 9.4 2.1e-05 24.3 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE07350.1 - 2.7e-05 24.1 5.2 2.7e-05 24.1 5.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGE07350.1 - 0.00018 21.8 11.6 0.0031 17.8 5.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 EGE07350.1 - 0.00048 20.0 6.7 0.0011 18.9 6.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGE07350.1 - 0.00094 19.0 7.7 0.0021 17.9 7.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE07350.1 - 0.0022 17.8 6.2 0.0022 17.8 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE07350.1 - 0.0029 17.7 8.8 0.015 15.5 8.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING GAGA PF09237.11 EGE07350.1 - 0.4 10.5 2.8 0.43 10.4 0.3 2.3 2 0 0 2 2 2 0 GAGA factor UCH PF00443.29 EGE07351.1 - 2.1e-44 152.0 0.0 3.4e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07351.1 - 5.4e-14 52.5 0.0 2e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DLH PF01738.18 EGE07352.1 - 5.5e-27 94.7 0.0 6.4e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGE07352.1 - 0.005 16.8 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EGE07352.1 - 0.022 14.4 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 EGE07352.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chs7 PF12271.8 EGE07353.1 - 3e-76 256.5 2.1 3.4e-76 256.4 2.1 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 EGE07353.1 - 0.0042 17.2 0.3 0.0042 17.2 0.3 2.6 2 1 0 2 2 2 1 M penetrans paralogue family 26 UPF0220 PF05255.11 EGE07353.1 - 0.054 13.1 0.9 0.11 12.1 0.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) PsbW PF07123.12 EGE07353.1 - 0.13 12.2 1.7 0.92 9.5 0.2 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) MASE3 PF17159.4 EGE07353.1 - 0.28 10.8 8.6 0.053 13.1 4.8 1.6 1 1 1 2 2 2 0 Membrane-associated sensor domain DUF2569 PF10754.9 EGE07353.1 - 0.48 10.9 10.8 0.75 10.2 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) DUF2781 PF10914.8 EGE07353.1 - 0.5 10.8 4.3 0.41 11.1 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) GPI-anchored PF10342.9 EGE07354.1 - 2.3e-25 89.1 0.0 4.7e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4589 PF15252.6 EGE07356.1 - 0.36 10.8 2.6 0.45 10.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CENP-B_dimeris PF09026.10 EGE07356.1 - 5.6 7.4 11.0 8.9 6.8 11.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EGE07356.1 - 6.6 6.4 8.6 7.8 6.1 8.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_N_3 PF13417.6 EGE07357.1 - 2.7e-08 34.1 0.0 2.6e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE07357.1 - 1.9e-05 24.8 0.1 0.00079 19.7 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EGE07357.1 - 0.018 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Cellulase PF00150.18 EGE07358.1 - 1.4e-14 54.2 0.1 1.4e-14 54.2 0.1 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3385 PF11865.8 EGE07359.1 - 0.005 16.8 0.3 0.018 15.0 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Pex2_Pex12 PF04757.14 EGE07360.1 - 4.4e-35 121.3 1.0 6e-35 120.9 1.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EGE07360.1 - 0.024 14.5 2.5 0.062 13.2 2.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE07360.1 - 0.029 14.5 5.6 0.029 14.5 5.6 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGE07360.1 - 0.047 13.7 6.6 0.25 11.4 6.6 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGE07360.1 - 0.68 9.8 6.2 1 9.2 1.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE07360.1 - 1.2 9.6 8.5 5.4 7.4 4.3 2.4 2 0 0 2 2 2 0 Ring finger domain DUF1772 PF08592.11 EGE07361.1 - 1.9e-29 102.7 1.5 2.6e-29 102.3 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) ILVD_EDD PF00920.21 EGE07362.1 - 9.9e-210 697.5 2.2 1.1e-209 697.3 2.2 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1610 PF07754.11 EGE07362.1 - 0.075 13.0 0.2 22 5.1 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) Abhydrolase_1 PF00561.20 EGE07363.1 - 2.1e-13 50.5 0.1 4.4e-12 46.2 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE07363.1 - 1.1e-12 49.1 2.3 2.5e-12 47.9 2.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE07363.1 - 1.2e-11 44.4 0.0 5.9e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EGE07363.1 - 2.9e-07 30.3 0.0 7.6e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LIDHydrolase PF10230.9 EGE07363.1 - 0.00076 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EGE07363.1 - 0.0012 18.7 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 EGE07363.1 - 0.0027 17.4 0.2 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 EGE07363.1 - 0.0036 17.4 0.0 0.0064 16.6 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGE07363.1 - 0.0047 16.5 0.0 0.016 14.8 0.0 1.8 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Thioesterase PF00975.20 EGE07363.1 - 0.043 13.9 0.2 0.089 12.9 0.2 1.5 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.15 EGE07363.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGE07363.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ribosomal_S19e PF01090.19 EGE07364.1 - 1.5e-58 196.3 0.2 1.7e-58 196.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e CPSF100_C PF13299.6 EGE07365.1 - 8 6.6 6.5 10 6.2 0.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Aldo_ket_red PF00248.21 EGE07366.1 - 2.3e-44 151.8 0.0 5e-42 144.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SCHIP-1 PF10148.9 EGE07366.1 - 0.00031 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Schwannomin-interacting protein 1 Dev_Cell_Death PF10539.9 EGE07366.1 - 0.017 15.0 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain APH PF01636.23 EGE07368.1 - 5.4e-06 26.5 0.0 1.2e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family eRF1_1 PF03463.15 EGE07369.1 - 7.3e-46 155.4 0.0 1.8e-45 154.1 0.0 1.7 1 1 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EGE07369.1 - 1.7e-17 63.9 0.0 2.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EGE07369.1 - 2.8e-15 56.8 0.0 7.2e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 eRF1 domain 2 LptE PF04390.12 EGE07369.1 - 0.085 13.6 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Myb_DNA-bind_4 PF13837.6 EGE07370.1 - 0.0056 17.0 3.2 0.02 15.3 0.8 2.4 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE07374.1 - 0.00016 21.8 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE07376.1 - 3e-15 56.1 3.0 5.2e-09 36.2 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE07376.1 - 1.4e-09 38.1 1.0 3.7e-06 27.1 0.2 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGE07376.1 - 0.049 13.5 0.8 0.12 12.3 0.8 1.7 1 0 0 1 1 1 0 Myb DNA-binding like COX5B PF01215.19 EGE07378.1 - 2.4e-49 166.3 0.1 3.2e-49 165.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EGE07378.1 - 0.062 13.1 0.1 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-bind_6 PF13921.6 EGE07382.1 - 9.3e-13 48.2 0.0 7.2e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE07382.1 - 1.8e-10 40.8 0.1 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF3357 PF11837.8 EGE07383.1 - 0.12 12.9 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) LRIF1 PF15741.5 EGE07385.1 - 0.15 10.6 0.7 0.17 10.4 0.7 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Med19 PF10278.9 EGE07385.1 - 0.24 11.3 8.5 0.33 10.9 8.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CTP_synth_N PF06418.14 EGE07387.1 - 1e-104 349.6 0.0 1.3e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGE07387.1 - 1.9e-55 187.6 0.0 3e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGE07387.1 - 8.3e-06 25.7 0.1 0.02 14.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase C26 PROCN PF08083.11 EGE07389.1 - 6.4e-236 782.6 9.0 6.4e-236 782.6 9.0 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGE07389.1 - 1.2e-126 421.0 2.6 2e-126 420.2 2.6 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGE07389.1 - 9.9e-83 275.8 1.4 1.7e-57 193.9 0.3 3.0 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGE07389.1 - 2.4e-80 267.8 1.8 2.4e-80 267.8 1.8 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain PROCT PF08084.11 EGE07389.1 - 1.5e-48 163.7 0.8 2.9e-48 162.9 0.1 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 EGE07389.1 - 3.2e-48 162.0 0.3 8.8e-48 160.6 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 EGE07389.1 - 5e-08 33.2 0.0 5e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint Hom_end PF05204.14 EGE07389.1 - 0.0063 16.7 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 Homing endonuclease U5_2-snRNA_bdg PF10597.9 EGE07389.1 - 0.028 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Ribosomal_L34e PF01199.18 EGE07390.1 - 4.4e-43 145.5 2.9 6.6e-43 144.9 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EGE07390.1 - 0.031 13.7 1.4 0.041 13.3 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EGE07390.1 - 0.66 10.0 5.1 3.5 7.7 0.3 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain XLF PF09302.11 EGE07391.1 - 1.3e-53 181.9 0.1 1.3e-53 181.9 0.1 1.6 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Cactin_mid PF10312.9 EGE07392.1 - 6.2e-66 221.9 6.0 6.2e-66 221.9 6.0 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EGE07392.1 - 7.9e-57 190.6 6.2 1.3e-56 189.9 6.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Pox_VLTF3 PF04947.14 EGE07392.1 - 0.18 11.5 1.3 0.52 10.0 0.2 2.1 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like Forkhead PF00250.18 EGE07393.1 - 2e-18 66.4 0.3 4.4e-18 65.3 0.3 1.6 1 0 0 1 1 1 1 Forkhead domain Zn_ribbon_17 PF17120.5 EGE07394.1 - 0.01 15.5 7.7 0.01 15.5 7.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 EGE07394.1 - 0.18 12.0 8.1 0.54 10.5 0.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon like family WD40 PF00400.32 EGE07395.1 - 2.6e-18 66.0 9.8 5.8e-07 30.1 0.2 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE07395.1 - 3.9e-09 36.7 0.2 0.37 11.1 0.0 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE07395.1 - 7e-05 22.8 0.0 0.023 14.6 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGE07395.1 - 0.00075 19.4 0.2 0.067 13.2 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EGE07395.1 - 0.01 14.6 0.4 2.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region ABC_membrane PF00664.23 EGE07397.1 - 1.8e-35 122.9 8.1 1.8e-35 122.9 8.1 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGE07397.1 - 1.8e-33 116.0 0.0 4.3e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGE07397.1 - 6.1e-08 32.4 0.1 1.7e-05 24.4 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE07397.1 - 0.013 15.8 0.0 0.067 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGE07397.1 - 0.015 15.5 0.5 0.42 10.9 0.5 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGE07397.1 - 0.047 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGE07397.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGE07397.1 - 0.057 13.8 1.3 0.32 11.4 1.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain DUF498 PF04430.14 EGE07398.1 - 1.6e-31 108.6 0.0 2.3e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 EGE07399.1 - 1.4e-108 363.6 0.0 1.7e-108 363.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGE07399.1 - 7.5e-05 22.2 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Pro_dh PF01619.18 EGE07400.1 - 1.6e-62 211.7 0.0 2.4e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.21 EGE07402.1 - 2e-60 203.4 0.7 2.3e-60 203.2 0.7 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF2417 PF10329.9 EGE07403.1 - 1.4e-80 270.2 0.4 1.9e-80 269.7 0.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Pox_A9 PF04835.12 EGE07403.1 - 0.023 14.8 2.0 3.8 7.7 0.1 2.6 2 0 0 2 2 2 0 A9 protein conserved region Trp_oprn_chp PF09534.10 EGE07403.1 - 0.1 12.4 3.2 0.056 13.2 0.7 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Abhydrolase_6 PF12697.7 EGE07404.1 - 1e-23 85.1 0.3 1.3e-23 84.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE07404.1 - 1.1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE07404.1 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGE07404.1 - 0.072 13.2 0.1 0.37 10.8 0.1 2.0 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGE07404.1 - 0.083 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGE07404.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.32 EGE07405.1 - 3.5e-48 160.6 27.5 9.1e-09 35.8 0.4 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGE07405.1 - 2.8e-35 121.4 0.1 4e-35 120.9 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGE07405.1 - 3.4e-14 52.9 1.0 0.015 15.6 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EGE07405.1 - 1.5e-07 31.1 0.0 4.2e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EGE07405.1 - 6.1e-07 28.5 1.7 0.00014 20.7 0.2 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGE07405.1 - 0.00079 18.5 0.3 0.063 12.2 0.0 3.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGE07405.1 - 0.0024 16.7 0.1 3 6.5 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.11 EGE07405.1 - 0.018 14.9 0.3 0.071 13.0 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4550 PF15084.6 EGE07405.1 - 0.077 13.4 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) PALB2_WD40 PF16756.5 EGE07405.1 - 5.2 5.9 5.4 0.77 8.6 0.8 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Med11 PF10280.9 EGE07406.1 - 2.3e-41 141.5 0.1 3e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Mediator complex protein DUF5344 PF17279.2 EGE07406.1 - 0.0022 18.5 0.1 0.0049 17.4 0.1 1.6 1 1 0 1 1 1 1 Family of unknown function (DUF5344) F_actin_cap_B PF01115.17 EGE07407.1 - 7.2e-106 353.2 0.0 8.3e-106 353.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Helicase_C PF00271.31 EGE07408.1 - 2.4e-20 72.9 0.1 6.1e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE07408.1 - 8.3e-20 71.5 0.0 1.6e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE07408.1 - 2.5e-15 56.7 0.0 7.1e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGE07408.1 - 0.0047 16.2 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EGE07408.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF676 PF05057.14 EGE07409.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2920 PF11144.8 EGE07409.1 - 0.17 11.0 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) V-ATPase_G PF03179.15 EGE07410.1 - 4.4e-21 75.4 11.9 6.1e-21 74.9 11.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 EGE07410.1 - 0.0059 17.0 5.6 0.0086 16.5 5.6 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RGS-like PF09128.11 EGE07410.1 - 0.042 13.6 1.8 0.051 13.3 1.8 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Tai4 PF16695.5 EGE07410.1 - 0.34 11.5 2.8 0.73 10.4 0.3 2.0 1 1 1 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein ATP-synt_B PF00430.18 EGE07410.1 - 1.4 9.0 10.4 3.5 7.7 10.3 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4407 PF14362.6 EGE07410.1 - 2.5 7.4 6.8 2.9 7.2 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PET117 PF15786.5 EGE07411.1 - 2.4e-26 91.8 1.2 2.9e-26 91.5 1.2 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial THEG4 PF15834.5 EGE07411.1 - 0.14 12.1 0.1 0.21 11.6 0.1 1.4 1 1 0 1 1 1 0 Testis highly expressed protein 4 DivIVA PF05103.13 EGE07412.1 - 0.00056 20.0 21.4 0.0066 16.5 6.7 3.4 2 1 1 3 3 3 2 DivIVA protein HAP1_N PF04849.13 EGE07412.1 - 0.034 13.3 0.4 0.034 13.3 0.4 3.1 2 1 0 2 2 2 0 HAP1 N-terminal conserved region Fib_alpha PF08702.10 EGE07412.1 - 1.8 8.8 16.5 1.7 8.8 6.2 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EGE07412.1 - 2.1 7.6 19.4 0.013 14.9 5.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EGE07412.1 - 8.1 5.7 18.5 0.92 8.8 13.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TBCC PF07986.12 EGE07413.1 - 3.2e-24 85.0 1.2 5.7e-24 84.2 0.7 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGE07413.1 - 4e-12 46.6 4.4 6.2e-12 46.0 0.1 2.3 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain GCH_III PF05165.12 EGE07413.1 - 0.082 12.2 0.8 0.21 10.8 0.2 1.9 2 0 0 2 2 2 0 GTP cyclohydrolase III Ndc1_Nup PF09531.10 EGE07413.1 - 0.12 11.0 2.8 0.14 10.8 2.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DAG_kinase_N PF14513.6 EGE07413.1 - 4 7.6 7.5 13 6.0 7.5 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus JAB PF01398.21 EGE07414.1 - 5.3e-14 52.2 0.0 8.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGE07414.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-HC5HC2H_2 PF13832.6 EGE07415.1 - 3.7e-24 85.0 18.1 4.3e-24 84.8 0.7 4.3 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGE07415.1 - 2.5e-22 78.9 20.4 2e-21 76.0 2.3 4.1 3 1 0 3 3 3 2 PHD-like zinc-binding domain BAH PF01426.18 EGE07415.1 - 1e-15 57.7 1.0 1.5e-15 57.1 0.1 1.8 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 EGE07415.1 - 3.6e-14 52.4 42.0 2.8e-07 30.3 7.3 4.0 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.6 EGE07415.1 - 2.5e-08 33.3 3.9 2.5e-08 33.3 3.9 4.1 4 0 0 4 4 4 1 PHD-finger C1_2 PF03107.16 EGE07415.1 - 0.0054 17.0 27.3 0.036 14.4 0.2 4.6 4 0 0 4 4 4 2 C1 domain C1_1 PF00130.22 EGE07415.1 - 0.0061 16.4 2.3 0.0061 16.4 2.3 4.8 4 1 1 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 EGE07415.1 - 0.0062 16.7 2.4 0.0062 16.7 2.4 3.9 4 0 0 4 4 4 2 FYVE-type zinc finger Zf_RING PF16744.5 EGE07415.1 - 9.6 6.4 33.1 0.1 12.7 4.0 4.5 3 1 1 4 4 4 0 KIAA1045 RING finger Podoplanin PF05808.11 EGE07416.1 - 0.0014 18.7 0.8 0.0035 17.5 0.8 1.6 1 0 0 1 1 1 1 Podoplanin DUF575 PF04746.12 EGE07416.1 - 0.0035 17.6 0.3 0.0062 16.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF575) TMEM154 PF15102.6 EGE07416.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DAP10 PF07213.11 EGE07416.1 - 0.016 15.2 1.8 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 DAP10 membrane protein Sporozoite_P67 PF05642.11 EGE07416.1 - 0.036 12.2 3.9 0.044 11.9 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TrbC PF04956.13 EGE07416.1 - 0.055 13.7 0.2 0.091 13.0 0.2 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF5383 PF17355.2 EGE07416.1 - 0.064 13.6 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) Ashwin PF15323.6 EGE07416.1 - 0.069 13.2 2.2 0.12 12.4 2.2 1.3 1 0 0 1 1 1 0 Developmental protein DUF5305 PF17231.2 EGE07416.1 - 0.072 12.5 0.3 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 EGE07416.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Rifin DUF2749 PF10907.8 EGE07416.1 - 1 9.6 2.8 3.6 7.8 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) RAP1 PF07218.11 EGE07416.1 - 4.2 5.5 10.3 5.8 5.1 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.12 EGE07416.1 - 9.9 4.4 11.2 14 3.9 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Malate_synthase PF01274.22 EGE07417.1 - 1.1e-227 756.5 0.0 1.2e-227 756.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EGE07417.1 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family PsbH PF00737.20 EGE07418.1 - 0.075 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein FMO-like PF00743.19 EGE07419.1 - 8.5e-16 57.5 0.0 6.8e-12 44.6 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGE07419.1 - 4.1e-10 39.7 0.1 1.9e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE07419.1 - 6.2e-09 35.5 0.0 0.00089 18.6 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE07419.1 - 1.8e-05 24.5 0.1 0.0028 17.3 0.1 3.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGE07419.1 - 0.0005 19.4 0.0 0.61 9.3 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07419.1 - 0.0017 17.6 0.1 0.074 12.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGE07419.1 - 0.01 15.8 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGE07419.1 - 0.067 13.8 0.8 0.8 10.3 0.0 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGE07419.1 - 0.2 10.9 0.0 0.47 9.6 0.0 1.5 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EGE07419.1 - 0.28 9.8 0.6 0.48 9.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Glyco_hydro_3_C PF01915.22 EGE07420.1 - 2.5e-45 154.9 0.0 4.4e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGE07420.1 - 2.3e-33 115.9 0.0 3.4e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGE07420.1 - 2.1e-22 79.0 0.1 4.7e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Serpin PF00079.20 EGE07421.1 - 1.9e-53 182.1 0.0 2.5e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) AA_permease_2 PF13520.6 EGE07422.1 - 6.5e-52 176.8 55.0 8e-52 176.5 55.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE07422.1 - 1.5e-19 69.9 40.7 2.1e-19 69.5 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4668 PF15701.5 EGE07422.1 - 1.2 8.9 5.6 0.45 10.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) LapA_dom PF06305.11 EGE07422.1 - 2.8 7.8 6.2 0.44 10.4 0.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF805 PF05656.14 EGE07423.1 - 1.1 9.7 6.8 2.5 8.6 6.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) GST_N_2 PF13409.6 EGE07424.1 - 5.2e-12 45.9 0.0 1.1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE07424.1 - 4.4e-10 39.8 0.0 9.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE07424.1 - 4.9e-05 23.3 0.1 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE07424.1 - 0.00052 20.2 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE07424.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 EGE07425.1 - 6.8e-45 153.0 0.1 2.2e-24 86.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGE07425.1 - 3.2e-15 56.7 0.6 0.00041 20.3 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE07425.1 - 2.8e-11 43.3 0.2 0.0011 18.5 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EGE07425.1 - 2.4e-08 33.7 0.1 5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EGE07425.1 - 2.5e-08 34.0 0.0 0.013 15.6 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGE07425.1 - 5.4e-07 30.3 0.7 0.0058 17.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EGE07425.1 - 8.6e-07 29.0 0.1 0.027 14.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGE07425.1 - 1.7e-05 24.5 2.5 0.11 12.3 1.2 2.9 2 1 1 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 EGE07425.1 - 0.00023 21.3 1.3 0.064 13.4 0.1 3.4 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_28 PF13521.6 EGE07425.1 - 0.00034 20.9 0.0 0.015 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE07425.1 - 0.00039 20.7 0.0 0.81 10.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGE07425.1 - 0.0005 20.0 0.7 0.24 11.3 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 EGE07425.1 - 0.00066 19.5 0.0 0.89 9.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 EGE07425.1 - 0.0017 18.7 0.1 1.8 9.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EGE07425.1 - 0.0031 18.1 0.4 4.8 7.7 0.0 3.4 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 EGE07425.1 - 0.0077 16.4 0.0 8.2 6.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EGE07425.1 - 0.012 15.8 0.1 8.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGE07425.1 - 0.016 14.9 1.2 1.2 8.8 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE07425.1 - 0.018 14.8 0.5 2 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EGE07425.1 - 0.021 13.8 0.4 4 6.3 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 EGE07425.1 - 0.025 14.2 0.1 5 6.7 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 EGE07425.1 - 0.027 14.2 0.1 0.92 9.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ALF PF03752.13 EGE07425.1 - 0.031 14.3 2.2 0.26 11.3 0.6 2.7 2 0 0 2 2 2 0 Short repeats of unknown function NB-ARC PF00931.22 EGE07425.1 - 0.031 13.4 0.9 0.93 8.6 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.29 EGE07425.1 - 0.032 14.7 0.1 2.9 8.3 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 EGE07425.1 - 0.051 12.2 0.0 4.6 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGE07425.1 - 0.054 13.7 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.9 EGE07425.1 - 0.057 13.0 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ploopntkinase3 PF18751.1 EGE07425.1 - 0.075 12.9 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 HEAT PF02985.22 EGE07425.1 - 0.077 13.3 0.3 1.1e+02 3.5 0.0 4.5 5 0 0 5 5 4 0 HEAT repeat MukB PF04310.12 EGE07425.1 - 0.097 12.5 0.3 2 8.2 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal DUF3584 PF12128.8 EGE07425.1 - 0.11 10.0 2.9 1.2 6.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1666 PF07891.12 EGE07425.1 - 0.11 12.1 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) AAA_16 PF13191.6 EGE07425.1 - 0.13 12.6 0.1 35 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF815 PF05673.13 EGE07425.1 - 0.17 11.0 0.5 6.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Glyco_hydro_92 PF07971.12 EGE07426.1 - 2.4e-146 488.3 0.3 2.9e-146 488.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGE07426.1 - 8.3e-61 205.9 0.7 1.3e-60 205.2 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Citrate_synt PF00285.21 EGE07427.1 - 3.6e-98 329.0 0.0 4.3e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 EGE07428.1 - 1.2e-194 647.7 0.1 1.4e-194 647.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EGE07428.1 - 2.6e-10 40.2 0.0 1.5e-09 37.7 0.0 1.9 1 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AMP-binding PF00501.28 EGE07429.1 - 2.6e-64 217.4 0.0 3.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE07429.1 - 2.7e-06 28.2 0.1 7.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.11 EGE07429.1 - 0.12 12.0 0.4 0.31 10.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) MmgE_PrpD PF03972.14 EGE07430.1 - 5e-126 420.8 0.0 2.1e-70 237.5 0.2 2.0 1 1 1 2 2 2 2 MmgE/PrpD family DNA_methylase PF00145.17 EGE07431.1 - 1.3e-42 146.4 0.0 2.4e-32 112.6 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 EGE07432.1 - 1.4e-13 51.2 0.0 3.1e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGE07432.1 - 2.3e-11 43.7 0.0 7.2e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGE07432.1 - 2.7e-07 30.2 0.0 6.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGE07432.1 - 0.00057 18.9 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.25 EGE07433.1 - 7.2e-08 32.8 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.22 EGE07434.1 - 1.7e-122 409.3 0.0 2e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2992 PF11208.8 EGE07435.1 - 0.014 15.6 3.7 0.036 14.3 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pkinase PF00069.25 EGE07436.1 - 9.6e-28 97.3 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07436.1 - 7.8e-18 64.7 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE07436.1 - 0.0045 16.9 0.0 0.0078 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE07436.1 - 0.01 14.6 0.1 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EGE07436.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGE07436.1 - 0.025 14.0 0.1 0.054 12.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_binding PF01877.17 EGE07436.1 - 0.11 12.7 0.0 0.88 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding F-box-like_2 PF13013.6 EGE07437.1 - 0.065 13.2 0.1 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.7 EGE07437.1 - 0.11 12.4 0.4 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 F-box-like Mt_ATP-synt_D PF05873.12 EGE07439.1 - 7.2e-24 84.4 2.4 8.8e-24 84.1 2.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 EGE07439.1 - 0.014 13.6 0.5 0.015 13.5 0.5 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 T2SSM_b PF10741.9 EGE07439.1 - 0.021 14.6 0.3 0.088 12.6 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF948 PF06103.11 EGE07439.1 - 0.12 12.7 1.5 0.88 9.9 0.4 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NAC PF01849.18 EGE07440.1 - 3.2e-22 78.2 0.0 1.1e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 NAC domain Cytomega_UL84 PF06284.11 EGE07440.1 - 0.15 10.5 0.5 0.17 10.3 0.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Shadoo PF14999.6 EGE07440.1 - 0.2 11.8 3.5 0.36 10.9 3.5 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PGA2 PF07543.12 EGE07440.1 - 7.1 6.6 12.3 3.3 7.7 8.1 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 Myc_N PF01056.18 EGE07440.1 - 8.8 6.1 9.4 2.1 8.2 5.8 1.6 1 1 1 2 2 2 0 Myc amino-terminal region Ribosomal_L14e PF01929.17 EGE07441.1 - 4.5e-31 107.2 1.9 6.1e-31 106.7 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGE07441.1 - 9.3e-07 28.6 1.0 1.9e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 KOW motif MFS_1 PF07690.16 EGE07442.1 - 3.7e-43 147.8 41.0 2.9e-34 118.6 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE07442.1 - 6.8e-11 41.7 12.6 2.7e-10 39.7 5.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGE07442.1 - 7.8e-06 25.4 3.5 7.8e-06 25.4 3.5 2.6 2 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EGE07442.1 - 1.4e-05 24.1 10.4 0.00047 19.1 0.3 3.4 2 2 1 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 EGE07442.1 - 4.2e-05 22.3 13.9 0.13 10.7 2.5 3.6 2 2 2 4 4 4 3 MFS/sugar transport protein Folate_carrier PF01770.18 EGE07442.1 - 0.0027 16.5 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Reduced folate carrier LacY_symp PF01306.19 EGE07442.1 - 0.0042 15.9 3.7 0.27 9.9 0.0 2.3 2 1 0 2 2 2 2 LacY proton/sugar symporter SRP-alpha_N PF04086.13 EGE07443.1 - 7.5e-77 259.1 0.0 1e-76 258.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EGE07443.1 - 1.5e-50 171.6 0.0 2.5e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EGE07443.1 - 6.6e-10 39.1 0.1 1.9e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGE07443.1 - 2e-06 27.0 0.0 3.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EGE07443.1 - 0.00091 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGE07443.1 - 0.0069 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE07443.1 - 0.0085 16.5 0.0 0.027 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 EGE07443.1 - 0.012 15.7 0.0 0.043 13.9 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 EGE07443.1 - 0.028 14.5 0.1 0.15 12.1 0.1 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EGE07443.1 - 0.028 14.3 0.2 0.25 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EGE07443.1 - 0.043 14.3 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EGE07443.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 EGE07443.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EGE07443.1 - 0.13 11.4 0.2 13 4.9 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase YIF1 PF03878.15 EGE07444.1 - 2.8e-98 328.2 4.0 3.3e-98 328.0 4.0 1.0 1 0 0 1 1 1 1 YIF1 Catalase PF00199.19 EGE07445.1 - 2.4e-174 579.9 0.9 3e-174 579.6 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGE07445.1 - 1.7e-16 60.2 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EGE07445.1 - 2.1e-08 33.9 0.3 1.4e-07 31.3 0.0 2.4 3 0 0 3 3 3 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EGE07445.1 - 0.00044 20.1 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family RabGAP-TBC PF00566.18 EGE07448.1 - 5.8e-38 130.7 4.7 1.1e-37 129.8 4.7 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EGE07448.1 - 1.3e-06 28.0 0.0 0.00089 18.8 0.0 3.5 3 1 0 3 3 3 1 Rab-binding domain (RBD) GAS2 PF02187.17 EGE07449.1 - 4.6e-06 26.6 0.3 1e-05 25.6 0.3 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 EGE07450.1 - 2.5e-108 361.6 0.0 2.9e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 EGE07451.1 - 2.5e-110 368.9 0.1 3.3e-110 368.5 0.1 1.1 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EGE07451.1 - 1.2e-32 112.9 0.1 2.6e-32 111.9 0.1 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 EGE07451.1 - 2.1e-21 77.2 14.4 2.1e-21 77.2 14.4 3.5 3 0 0 3 3 3 2 Vesicle coat trafficking protein Sec16 N-terminus GIY-YIG PF01541.24 EGE07453.1 - 0.033 14.5 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain PhoLip_ATPase_C PF16212.5 EGE07454.1 - 1.6e-46 159.1 6.6 1.6e-46 159.1 6.6 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGE07454.1 - 4.6e-16 58.3 1.7 9.3e-16 57.3 1.7 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGE07454.1 - 8.2e-13 49.1 0.1 5.9e-08 33.3 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGE07454.1 - 1e-05 25.1 1.4 0.023 14.2 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EGE07454.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGE07454.1 - 0.021 14.9 0.1 16 5.7 0.0 3.8 3 1 0 3 3 3 0 Cation transport ATPase (P-type) HIGH_NTase1_ass PF16581.5 EGE07454.1 - 0.032 14.2 0.1 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Mso1_Sec1_bdg PF14475.6 EGE07455.1 - 4.8e-13 48.5 0.0 8.3e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sporozoite_P67 PF05642.11 EGE07455.1 - 1.5 6.9 6.4 2 6.4 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L28e PF01778.17 EGE07456.1 - 1.5e-38 132.1 0.6 2.6e-38 131.3 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EGE07456.1 - 3e-30 104.8 14.0 3e-30 104.8 14.0 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGE07456.1 - 9.2e-06 25.3 14.6 1.1e-05 25.0 14.6 1.1 1 0 0 1 1 1 1 BUD22 Ribosomal_L24e PF01246.20 EGE07456.1 - 0.0085 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e PYC_OADA PF02436.18 EGE07456.1 - 0.025 14.3 1.3 0.043 13.6 0.9 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 EGE07456.1 - 0.091 11.3 24.7 0.11 11.1 24.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EGE07456.1 - 4.9 5.2 27.4 6 4.9 27.4 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_4 PF13894.6 EGE07457.1 - 2.2e-08 34.2 29.2 0.52 11.3 0.7 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE07457.1 - 0.0058 17.0 27.7 1.3 9.6 1.9 6.0 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGE07457.1 - 0.07 13.5 17.3 0.34 11.3 3.9 3.6 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-B_box PF00643.24 EGE07457.1 - 2.3 8.5 27.4 0.31 11.2 0.9 4.8 4 1 0 4 4 4 0 B-box zinc finger zf_C2H2_ZHX PF18387.1 EGE07457.1 - 5.9 6.6 16.9 0.084 12.5 0.9 3.7 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain ECH_1 PF00378.20 EGE07458.1 - 5.3e-25 88.2 0.0 6.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE07458.1 - 2.8e-18 66.5 0.0 3.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase D123 PF07065.14 EGE07459.1 - 5.1e-109 364.1 0.1 6.5e-109 363.8 0.1 1.1 1 0 0 1 1 1 1 D123 Vps51 PF08700.11 EGE07460.1 - 2.2e-13 50.1 0.0 1.6e-12 47.3 0.0 2.5 1 0 0 1 1 1 1 Vps51/Vps67 DUF1640 PF07798.11 EGE07461.1 - 5.7e-35 120.9 8.5 8.3e-35 120.4 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 EGE07461.1 - 0.0011 19.5 2.1 0.0036 17.9 2.1 1.9 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1387 PF07139.11 EGE07461.1 - 0.27 10.9 17.9 0.02 14.6 1.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1387) Baculo_PEP_C PF04513.12 EGE07461.1 - 0.85 9.7 5.9 1.5 8.8 5.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.8 EGE07461.1 - 8.2 5.1 13.1 0.029 13.2 2.2 2.2 2 1 1 3 3 3 0 Aluminium activated malate transporter HEAT_2 PF13646.6 EGE07462.1 - 6.4e-08 32.9 0.0 0.32 11.4 0.0 5.9 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EGE07462.1 - 3.4e-06 26.8 8.7 3.2 8.2 0.0 8.5 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 EGE07462.1 - 0.00034 21.0 9.0 28 5.4 0.1 6.9 6 0 0 6 6 6 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGE07462.1 - 0.00064 20.3 0.0 0.1 13.2 0.0 3.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGE07462.1 - 0.025 14.6 3.2 3.6 7.8 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGE07462.1 - 0.12 12.5 3.4 2.1 8.4 0.0 4.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 EGE07462.1 - 0.34 10.1 5.3 2.4 7.4 0.1 3.8 3 1 0 3 3 3 0 V-ATPase subunit H CLASP_N PF12348.8 EGE07462.1 - 5.5 6.5 8.2 17 4.9 0.1 4.4 5 0 0 5 5 5 0 CLASP N terminal Transcrip_reg PF01709.20 EGE07463.1 - 5.6e-73 245.3 0.1 6.4e-73 245.1 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.11 EGE07464.1 - 1.5e-45 155.9 0.6 9.6e-45 153.3 0.6 1.9 1 1 0 1 1 1 1 Mis6 Sedlin_N PF04628.13 EGE07464.1 - 0.038 14.1 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region DUF4360 PF14273.6 EGE07465.1 - 1e-48 165.5 1.0 1.2e-48 165.3 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CLPTM1 PF05602.12 EGE07467.1 - 7.9e-149 496.3 0.6 9.6e-149 496.0 0.6 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) MtN3_slv PF03083.16 EGE07467.1 - 0.31 11.1 3.5 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SyrA PF11089.8 EGE07467.1 - 0.45 10.6 2.3 17 5.6 0.6 2.6 2 0 0 2 2 2 0 Exopolysaccharide production repressor adh_short PF00106.25 EGE07468.1 - 5.3e-20 71.7 0.0 1.1e-19 70.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07468.1 - 9.8e-15 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ASXH PF13919.6 EGE07469.1 - 5.4e-36 123.7 1.0 1.1e-35 122.7 1.0 1.5 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.6 EGE07470.1 - 1.3e-25 89.2 0.6 2.2e-25 88.5 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGE07470.1 - 2.1e-15 56.3 0.8 7e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 EGE07470.1 - 0.011 15.7 1.4 0.18 11.8 0.0 2.2 1 1 1 2 2 2 0 Protein SLM4 SCVP PF17619.2 EGE07470.1 - 0.098 13.5 0.8 1.3 10.0 0.0 2.2 2 0 0 2 2 2 0 Secreted clade V proteins Bac_small_YrzI PF09501.10 EGE07470.1 - 0.12 12.6 0.5 0.26 11.5 0.5 1.6 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) DUF1664 PF07889.12 EGE07470.1 - 0.14 12.2 5.6 0.27 11.3 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SIMPL PF04402.14 EGE07470.1 - 0.36 11.2 3.8 1.2 9.6 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF541) YgaB PF14182.6 EGE07470.1 - 0.64 10.5 3.5 0.69 10.4 0.4 2.4 2 1 1 3 3 3 0 YgaB-like protein EMP24_GP25L PF01105.24 EGE07470.1 - 1.9 8.4 6.2 1.6 8.6 0.6 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Elong_Iki1 PF10483.9 EGE07471.1 - 1.5e-98 330.0 0.0 1.9e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 SNRNP27 PF08648.12 EGE07472.1 - 1.7e-26 92.1 1.8 3.7e-26 91.0 1.8 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DAO PF01266.24 EGE07473.1 - 1.4e-70 238.6 1.0 1.6e-70 238.4 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE07473.1 - 1.5e-07 31.5 0.3 6e-07 29.6 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE07473.1 - 5.4e-07 29.1 0.1 0.0078 15.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGE07473.1 - 0.00015 21.0 0.3 0.0024 17.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EGE07473.1 - 0.00086 18.6 0.1 0.0016 17.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EGE07473.1 - 0.00088 19.8 0.1 0.013 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGE07473.1 - 0.0017 17.3 0.1 0.12 11.2 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase MCRA PF06100.11 EGE07473.1 - 0.0064 15.3 0.3 0.012 14.4 0.1 1.4 2 0 0 2 2 2 1 MCRA family GIDA PF01134.22 EGE07473.1 - 0.01 15.0 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EGE07473.1 - 0.016 15.2 0.2 0.099 12.6 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGE07473.1 - 0.025 13.9 0.6 0.52 9.6 0.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EGE07473.1 - 0.029 14.6 0.1 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Mqo PF06039.15 EGE07473.1 - 0.14 10.7 0.0 9.2 4.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Glyco_hydro_63 PF03200.16 EGE07474.1 - 5.3e-175 582.9 5.5 5.3e-175 582.9 5.5 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGE07474.1 - 1.1e-88 297.1 0.0 9.5e-88 294.1 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGE07474.1 - 0.00084 18.3 0.7 0.0015 17.4 0.7 1.4 1 0 0 1 1 1 1 Trehalase MMtag PF10159.9 EGE07475.1 - 2.5e-33 114.2 3.2 2.5e-33 114.2 3.2 2.3 2 1 0 2 2 2 1 Multiple myeloma tumor-associated PAP1 PF08601.10 EGE07475.1 - 0.58 9.8 3.6 0.9 9.2 3.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CRT10 PF08728.10 EGE07476.1 - 1.4e-15 56.6 0.1 2.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 CRT10 DUF568 PF04526.13 EGE07476.1 - 0.12 13.1 0.2 0.29 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF568) WD40 PF00400.32 EGE07476.1 - 0.25 12.3 1.4 0.63 11.0 0.2 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat YL1 PF05764.13 EGE07476.1 - 6.2 6.9 14.9 11 6.1 14.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3402 PF11882.8 EGE07477.1 - 1.7e-169 564.8 0.0 2.2e-169 564.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EGE07477.1 - 1.6e-85 286.8 0.0 2.2e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein IBR PF01485.21 EGE07478.1 - 2.3e-18 66.2 41.4 7.3e-16 58.1 3.3 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EGE07478.1 - 3.2e-17 62.9 0.1 8.5e-17 61.5 0.1 1.8 1 1 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EGE07478.1 - 0.027 14.8 9.1 0.027 14.8 9.1 4.1 3 1 1 4 4 4 0 Ring finger domain PAP2 PF01569.21 EGE07479.1 - 3.1e-14 52.9 4.7 1.5e-13 50.7 4.7 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EGE07479.1 - 0.0018 18.4 0.1 0.67 10.1 0.0 2.3 2 0 0 2 2 2 2 Divergent PAP2 family Ldh_2 PF02615.14 EGE07480.1 - 1e-46 159.7 0.0 1.2e-46 159.5 0.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pet100 PF09803.9 EGE07481.1 - 2.7e-19 69.5 0.1 3.2e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Pet100 CSN7a_helixI PF18392.1 EGE07481.1 - 0.24 11.4 0.6 0.34 10.8 0.6 1.2 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain SPT_ssu-like PF11779.8 EGE07482.1 - 1.4e-23 82.2 5.2 1.9e-23 81.8 5.2 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 EGE07483.1 - 8.7e-25 86.9 6.8 1.3e-24 86.4 6.8 1.2 1 0 0 1 1 1 1 RF-1 domain Cwf_Cwc_15 PF04889.12 EGE07483.1 - 0.015 15.0 4.8 0.018 14.8 4.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XRN_M PF17846.1 EGE07483.1 - 0.3 10.0 2.2 0.37 9.7 2.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Cse1 PF08506.10 EGE07484.1 - 4.2e-157 522.7 3.9 6.3e-157 522.1 3.9 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EGE07484.1 - 1.6e-156 521.2 0.0 4e-156 520.0 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGE07484.1 - 1.1e-16 60.5 0.4 5e-16 58.4 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGE07484.1 - 0.021 14.9 1.0 1.7 8.7 0.0 4.2 3 1 0 3 3 3 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 EGE07484.1 - 0.089 12.1 2.1 0.19 11.0 0.1 2.5 3 0 0 3 3 3 0 V-ATPase subunit H DUF3384 PF11864.8 EGE07485.1 - 8e-89 298.7 0.3 4.3e-88 296.3 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EGE07485.1 - 1.3e-43 148.8 0.1 2.1e-43 148.1 0.1 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EGE07485.1 - 1.3e-40 139.7 1.7 1.1e-35 123.4 0.0 3.2 3 0 0 3 3 3 2 Tuberin GSHPx PF00255.19 EGE07486.1 - 1.7e-39 133.7 0.0 2.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EGE07486.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family Ral PF11058.8 EGE07486.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Antirestriction protein Ral DUF4677 PF15726.5 EGE07487.1 - 0.069 13.3 0.9 0.097 12.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) ORC6 PF05460.13 EGE07487.1 - 0.47 9.7 7.6 0.54 9.5 7.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hydrolase_6 PF13344.6 EGE07488.1 - 6.7e-24 83.9 0.0 1.4e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGE07488.1 - 4.8e-12 45.8 0.0 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EGE07488.1 - 0.034 14.4 0.0 15 5.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF676 PF05057.14 EGE07489.1 - 3.9e-48 163.8 0.0 5.9e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGE07489.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EGE07489.1 - 0.00042 20.2 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EGE07489.1 - 0.0011 19.6 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 EGE07489.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain PGAP1 PF07819.13 EGE07489.1 - 0.013 15.2 0.0 0.049 13.4 0.0 1.9 2 1 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 EGE07489.1 - 0.03 13.7 0.0 7.9 5.7 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L22e PF01776.17 EGE07491.1 - 6.5e-47 158.4 0.5 8.1e-47 158.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Translin PF01997.16 EGE07492.1 - 3.2e-54 184.0 0.0 3.7e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Translin family Rx_N PF18052.1 EGE07492.1 - 0.004 17.4 1.1 0.89 9.9 0.6 3.3 2 1 0 2 2 2 1 Rx N-terminal domain Syntaxin_2 PF14523.6 EGE07492.1 - 0.1 13.0 1.8 0.29 11.5 0.4 2.4 3 1 0 3 3 3 0 Syntaxin-like protein Pcc1 PF09341.10 EGE07493.1 - 1.4e-33 114.8 2.6 1.8e-33 114.5 2.6 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 EGE07494.1 - 2.7e-39 134.8 0.0 2e-37 128.8 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGE07494.1 - 8.5e-16 58.0 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE07494.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pyridoxal_deC PF00282.19 EGE07496.1 - 4.8e-61 206.5 0.0 6.9e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGE07496.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V DUF917 PF06032.12 EGE07497.1 - 1.3e-121 405.7 1.4 2.8e-121 404.6 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EGE07497.1 - 1.7e-31 109.6 6.3 2.3e-26 92.8 0.9 3.3 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGE07497.1 - 5.3e-27 94.7 1.8 1.1e-24 87.1 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EGE07497.1 - 0.00018 20.3 4.8 0.028 13.0 0.5 2.7 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.20 EGE07497.1 - 0.035 13.6 0.3 0.035 13.6 0.3 3.2 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family DUF3715 PF12509.8 EGE07497.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Cucumo_coat PF00760.18 EGE07497.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cucumovirus coat protein BRE PF06113.12 EGE07497.1 - 0.088 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) FtsA PF14450.6 EGE07497.1 - 0.36 11.3 7.5 7.9 7.0 0.4 3.7 3 2 0 3 3 3 0 Cell division protein FtsA Homeodomain PF00046.29 EGE07498.1 - 5.4e-14 51.8 1.2 1.2e-13 50.7 1.2 1.6 1 0 0 1 1 1 1 Homeodomain MFS_1 PF07690.16 EGE07499.1 - 2.6e-41 141.8 10.8 5.9e-34 117.5 12.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGE07499.1 - 2.6e-11 42.5 7.0 4.2e-11 41.8 3.5 2.7 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EGE07499.1 - 2.2e-10 40.0 9.1 5.6e-08 32.1 3.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGE07499.1 - 1.2e-06 28.1 1.7 0.0016 17.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EGE07499.1 - 0.00057 18.4 2.5 0.025 13.0 3.1 2.6 2 1 1 3 3 3 2 Transmembrane secretion effector MFS_2 PF13347.6 EGE07499.1 - 0.00088 17.9 16.9 0.0085 14.7 8.8 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein MscS_TM PF12794.7 EGE07499.1 - 0.0081 15.1 0.2 0.03 13.2 0.2 2.0 1 1 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 Fungal_trans_2 PF11951.8 EGE07500.1 - 1.6e-52 178.6 0.1 2.3e-52 178.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hamartin PF04388.12 EGE07500.1 - 6.4 5.3 6.9 9.5 4.7 6.9 1.2 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 EGE07501.1 - 9.4e-58 195.6 0.0 5.1e-57 193.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07501.1 - 9.9e-29 100.4 0.5 3.7e-20 72.3 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGE07501.1 - 0.00027 21.5 1.0 0.0008 20.1 1.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 EGE07501.1 - 0.00028 20.9 2.4 0.46 10.3 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE07501.1 - 0.00053 19.4 1.1 0.0015 17.9 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EGE07501.1 - 0.022 13.7 0.0 0.059 12.3 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGE07501.1 - 0.04 13.3 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.11 EGE07502.1 - 3e-26 92.4 0.0 4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) 1-cysPrx_C PF10417.9 EGE07502.1 - 0.061 13.2 0.0 8.8 6.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Abhydrolase_2 PF02230.16 EGE07503.1 - 6.1e-56 189.6 0.0 7.1e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGE07503.1 - 8.8e-08 31.9 0.1 1.9e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EGE07503.1 - 3.6e-06 26.7 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGE07503.1 - 6.6e-05 22.9 0.0 0.024 14.5 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EGE07503.1 - 9.6e-05 22.1 0.0 0.00031 20.5 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGE07503.1 - 0.00051 19.4 0.9 0.11 11.7 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE07503.1 - 0.0045 17.6 0.0 0.079 13.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EGE07503.1 - 0.046 13.4 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 EGE07503.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Ctr PF04145.15 EGE07505.1 - 1.3e-27 97.2 0.0 1.6e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.12 EGE07506.1 - 3.4e-20 72.1 0.0 8.2e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EGE07506.1 - 4.7e-18 65.8 0.0 1.9e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGE07506.1 - 9.1e-18 64.6 11.5 2.3e-17 63.3 11.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_3 PF01494.19 EGE07507.1 - 9.5e-71 238.8 0.2 1.2e-68 231.9 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EGE07507.1 - 6e-30 104.5 0.0 1.7e-29 103.0 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.10 EGE07507.1 - 0.012 14.6 0.0 0.043 12.9 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 EGE07507.1 - 0.076 11.8 0.1 0.15 10.9 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase DUF1664 PF07889.12 EGE07509.1 - 0.012 15.6 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5024 PF16427.5 EGE07509.1 - 0.077 13.3 0.4 3 8.2 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5024) BLOC1_2 PF10046.9 EGE07509.1 - 0.078 13.3 0.1 0.21 11.9 0.1 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Hrs_helical PF12210.8 EGE07509.1 - 0.14 12.7 2.2 12 6.6 0.2 2.4 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Wbp11 PF09429.10 EGE07511.1 - 2.1e-20 72.9 17.2 2.1e-20 72.9 17.2 2.1 3 0 0 3 3 3 1 WW domain binding protein 11 Nkap_C PF06047.11 EGE07511.1 - 0.056 13.6 0.1 0.056 13.6 0.1 2.5 2 1 1 3 3 3 0 NF-kappa-B-activating protein C-terminal domain Pkinase PF00069.25 EGE07513.1 - 4e-55 187.0 0.0 1.1e-33 116.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07513.1 - 7.9e-36 123.7 0.0 7.5e-35 120.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE07513.1 - 0.0057 15.5 0.4 0.071 11.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Spore_GerAC PF05504.11 EGE07513.1 - 0.23 11.7 2.6 0.54 10.5 2.6 1.6 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal DUF3896 PF13035.6 EGE07513.1 - 3 8.1 7.1 0.32 11.2 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) ALMT PF11744.8 EGE07513.1 - 3.6 6.3 5.9 5.7 5.7 5.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter BTB PF00651.31 EGE07514.1 - 1.6e-26 92.7 0.0 3.8e-13 49.6 0.3 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 EGE07514.1 - 8.3e-07 29.5 0.1 1.6e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE07514.1 - 3e-05 24.5 0.0 7.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE07514.1 - 0.00045 20.4 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGE07514.1 - 0.00092 19.6 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EGE07514.1 - 0.054 14.1 0.2 0.33 11.7 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat TRP PF06011.12 EGE07515.1 - 2e-77 260.7 23.4 5.3e-77 259.4 23.4 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EGE07515.1 - 2.5e-31 108.9 0.0 4.5e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ML-like domain PIG-F PF06699.11 EGE07515.1 - 0.0069 16.6 0.9 0.0069 16.6 0.9 3.0 3 0 0 3 3 3 1 GPI biosynthesis protein family Pig-F DUF4501 PF14946.6 EGE07515.1 - 6.9 6.7 8.7 0.93 9.5 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4501) zf-C2H2 PF00096.26 EGE07522.1 - 8.3e-09 35.4 11.2 0.00051 20.3 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE07522.1 - 6.1e-05 23.3 10.4 6.2e-05 23.2 1.0 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE07522.1 - 0.00059 20.4 9.8 0.12 13.3 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGE07522.1 - 0.031 14.7 3.1 0.077 13.4 1.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGE07522.1 - 0.11 12.5 0.7 0.11 12.5 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EGE07522.1 - 0.47 10.6 3.0 11 6.3 0.2 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 EGE07522.1 - 2.8 8.0 7.6 1 9.5 1.0 2.4 2 0 0 2 2 2 0 BED zinc finger adh_short PF00106.25 EGE07523.1 - 1.6e-21 76.7 0.0 2.2e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07523.1 - 1.4e-10 41.2 0.0 5.5e-07 29.4 0.0 2.6 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE07523.1 - 3.2e-09 37.0 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGE07523.1 - 0.0022 17.2 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EGE07523.1 - 0.049 13.9 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAC PF01849.18 EGE07524.1 - 1.1e-24 86.2 0.5 2.1e-24 85.2 0.5 1.5 1 0 0 1 1 1 1 NAC domain Sigma70_ner PF04546.13 EGE07524.1 - 1.7 8.4 6.4 1.1 9.1 1.7 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Rpr2 PF04032.16 EGE07525.1 - 1.1e-21 77.0 2.3 1.7e-21 76.3 1.7 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 EGE07525.1 - 0.033 14.3 0.6 0.041 14.0 0.6 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-Sec23_Sec24 PF04810.15 EGE07525.1 - 0.23 11.6 1.2 1 9.5 1.2 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 EGE07525.1 - 0.42 10.1 2.9 1.7 8.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DEAD PF00270.29 EGE07526.1 - 1.7e-35 122.4 0.0 3e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE07526.1 - 9.6e-27 93.5 0.0 4.1e-24 85.1 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGE07526.1 - 2.7e-09 37.3 0.0 5.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGE07526.1 - 0.00059 19.2 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 EGE07526.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ank_2 PF12796.7 EGE07527.1 - 2.4e-33 114.5 5.3 1.4e-11 44.8 0.0 6.1 3 3 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE07527.1 - 1.6e-24 85.9 9.1 1.5e-06 28.6 0.0 8.2 6 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGE07527.1 - 7.6e-20 70.7 9.4 7.7e-05 22.9 0.1 7.7 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE07527.1 - 1.6e-16 58.7 7.7 0.007 16.8 0.1 9.2 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 EGE07527.1 - 2.1e-07 31.1 9.2 0.56 10.8 0.2 8.1 9 0 0 9 9 9 2 Ankyrin repeat Sacchrp_dh_NADP PF03435.18 EGE07527.1 - 0.086 13.1 0.5 0.58 10.4 0.2 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EGE07528.1 - 6.7e-26 90.7 0.0 1e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EGE07528.1 - 4.4e-18 65.7 0.0 6.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 EGE07529.1 - 3.1e-20 72.3 4.5 4.4e-20 71.8 4.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF2076 PF09849.9 EGE07529.1 - 0.19 11.8 5.0 0.41 10.7 5.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Lipase_3 PF01764.25 EGE07530.1 - 9.3e-17 61.2 0.0 5.1e-12 45.9 0.0 2.6 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 EGE07530.1 - 0.039 14.6 0.4 0.095 13.3 0.4 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE07530.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RGS PF00615.19 EGE07531.1 - 3e-06 27.5 0.0 0.0019 18.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain SMC_N PF02463.19 EGE07532.1 - 1.5e-21 76.9 0.0 2.8e-21 76.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGE07532.1 - 8.7e-12 45.4 1.5 1.6e-08 34.7 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGE07532.1 - 1.8e-11 44.9 63.4 1.2e-10 42.2 28.1 5.5 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 EGE07532.1 - 0.00015 21.7 2.9 0.069 13.0 0.0 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE07532.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 EGE07532.1 - 0.017 15.2 11.1 1.7 8.7 0.4 4.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EGE07532.1 - 0.019 15.4 56.8 0.36 11.3 2.3 7.8 4 2 3 7 7 7 0 Snapin/Pallidin AAA_27 PF13514.6 EGE07532.1 - 0.35 10.4 0.0 0.35 10.4 0.0 4.5 4 2 3 8 8 8 0 AAA domain ABC_tran PF00005.27 EGE07532.1 - 0.44 11.1 0.0 0.44 11.1 0.0 4.3 4 1 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 EGE07532.1 - 2.1 7.9 7.6 0.83 9.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF4162 PF13732.6 EGE07532.1 - 8.9 7.1 12.4 2.3 9.0 1.5 4.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4162) AdoMet_MTase PF07757.13 EGE07533.1 - 3.4e-36 124.0 0.0 1.2e-18 67.4 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.8 EGE07534.1 - 8e-18 64.7 0.0 3e-14 53.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) DUF2722 PF10846.8 EGE07534.1 - 2.7e-05 23.3 3.5 3.2e-05 23.1 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) zf-BED PF02892.15 EGE07534.1 - 0.0005 20.0 4.9 0.17 11.9 0.5 2.3 2 0 0 2 2 2 2 BED zinc finger Spt20 PF12090.8 EGE07534.1 - 0.014 15.0 18.1 0.029 14.0 18.1 1.5 1 0 0 1 1 1 0 Spt20 family SARAF PF06682.12 EGE07534.1 - 0.053 13.2 9.5 0.1 12.2 9.5 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 EGE07534.1 - 0.3 9.8 0.8 0.37 9.5 0.8 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 EGE07534.1 - 0.37 11.4 20.9 0.055 14.1 9.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PyrI_C PF02748.15 EGE07534.1 - 1 9.3 6.0 7.2 6.6 0.5 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain SPX PF03105.19 EGE07534.1 - 1.2 9.0 6.0 1.6 8.6 6.0 1.2 1 0 0 1 1 1 0 SPX domain CCDC53 PF10152.9 EGE07534.1 - 2.9 8.3 14.0 0.8 10.1 5.2 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Ndc1_Nup PF09531.10 EGE07534.1 - 3 6.4 8.0 4.3 5.9 8.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 EGE07534.1 - 3 6.7 6.8 4.3 6.2 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 EGE07534.1 - 9.5 7.3 6.3 20 6.2 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Gln-synt_C PF00120.24 EGE07535.1 - 6.5e-77 258.8 0.0 8.2e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 EGE07536.1 - 2.1e-60 204.2 0.2 2.3e-60 204.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE07536.1 - 4.4e-42 143.8 0.1 5.6e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE07536.1 - 1.2e-11 44.9 0.7 1.9e-11 44.2 0.7 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGE07536.1 - 0.00011 22.1 0.2 0.00021 21.2 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EGE07536.1 - 0.00035 21.2 0.0 0.00075 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 EGE07536.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGE07536.1 - 0.016 14.7 0.1 0.023 14.1 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lig_C PF18330.1 EGE07536.1 - 0.045 13.8 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region RecC_C PF17946.1 EGE07536.1 - 0.046 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain 3Beta_HSD PF01073.19 EGE07536.1 - 0.059 12.4 0.1 0.26 10.2 0.1 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EGE07536.1 - 0.06 12.7 0.2 0.16 11.3 0.2 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 EGE07536.1 - 0.062 13.4 0.9 0.28 11.3 0.5 2.0 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 EGE07536.1 - 0.16 12.8 0.0 0.32 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ChuX_HutX PF06228.13 EGE07536.1 - 0.16 11.7 0.0 13 5.6 0.0 2.3 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX Eno-Rase_NADH_b PF12242.8 EGE07536.1 - 0.43 10.4 2.7 7.2 6.5 0.6 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Myco_arth_vir_N PF09610.10 EGE07536.1 - 0.73 10.0 3.7 8.7 6.5 1.4 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) BTB PF00651.31 EGE07537.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain CBP4 PF07960.11 EGE07538.1 - 3.6e-30 104.5 0.6 3.8e-30 104.4 0.6 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EGE07538.1 - 0.0031 17.4 0.0 0.0049 16.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Tmemb_161AB PF10268.9 EGE07538.1 - 0.053 12.2 0.1 0.053 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB FERM_F2 PF18377.1 EGE07538.1 - 0.092 12.7 0.8 0.12 12.4 0.8 1.2 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain Glyco_hydro_76 PF03663.14 EGE07539.1 - 1.3e-135 452.6 10.6 1.6e-135 452.4 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EGE07539.1 - 0.00017 20.8 10.1 0.039 13.0 1.4 3.2 2 1 0 3 3 3 3 Glycosyl Hydrolase Family 88 Rad21_Rec8_N PF04825.13 EGE07540.1 - 4.5e-32 110.5 0.0 8.2e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGE07540.1 - 0.014 14.7 0.1 0.028 13.7 0.1 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein T4BSS_DotH_IcmK PF12293.8 EGE07540.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion DUF4006 PF13179.6 EGE07540.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF4006) NAT PF04768.13 EGE07541.1 - 4e-52 176.3 0.1 8.5e-52 175.2 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EGE07541.1 - 9.3e-32 110.0 0.0 2.9e-31 108.4 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGE07541.1 - 5.7e-28 98.1 0.3 1.6e-27 96.6 0.0 1.8 2 0 0 2 2 2 1 Amino acid kinase family Synaptobrevin PF00957.21 EGE07542.1 - 2.4e-32 110.6 1.3 2.9e-32 110.3 1.3 1.1 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EGE07542.1 - 0.072 13.7 0.1 0.14 12.8 0.1 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor Aminotran_4 PF01063.19 EGE07543.1 - 0.027 14.3 0.1 0.037 13.9 0.1 1.3 1 0 0 1 1 1 0 Amino-transferase class IV Spt20 PF12090.8 EGE07544.1 - 0.027 14.1 3.0 0.032 13.8 3.0 1.1 1 0 0 1 1 1 0 Spt20 family Sel1 PF08238.12 EGE07545.1 - 7.7e-50 166.2 24.5 2.6e-09 37.4 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EGE07545.1 - 5.7 7.8 8.2 33 5.4 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.16 EGE07546.1 - 6e-13 48.5 0.0 7.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_hydro_36 PF17167.4 EGE07546.1 - 0.1 11.3 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain MPC PF03650.13 EGE07547.1 - 1e-47 160.8 0.2 1.6e-47 160.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Enoyl_reductase PF12241.8 EGE07547.1 - 0.036 13.4 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region FAD_binding_3 PF01494.19 EGE07548.1 - 8.1e-22 77.9 2.0 1.7e-13 50.6 1.0 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGE07548.1 - 6.1e-06 25.7 0.1 0.0045 16.3 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE07548.1 - 0.00011 22.4 0.2 0.00033 20.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE07548.1 - 0.00095 19.7 0.0 0.014 15.9 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE07548.1 - 0.0011 18.3 0.1 0.1 11.8 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGE07548.1 - 0.0078 15.3 2.2 0.051 12.6 0.5 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGE07548.1 - 0.01 15.0 0.2 0.023 13.8 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EGE07548.1 - 0.018 14.7 0.5 0.13 11.8 0.2 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGE07548.1 - 0.031 13.6 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGE07548.1 - 0.048 12.4 0.5 0.16 10.6 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EGE07548.1 - 0.1 12.5 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.6 EGE07550.1 - 1.7e-21 76.8 0.0 1.7e-21 76.8 0.0 2.2 1 1 1 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07550.1 - 7.2e-15 55.5 0.0 1.9e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07550.1 - 1.9e-13 50.9 0.0 4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07550.1 - 8.4e-12 45.1 0.9 8e-11 42.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07550.1 - 2.7e-10 40.9 0.1 1.7e-09 38.3 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 EGE07550.1 - 2.2e-06 27.2 0.0 4.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGE07550.1 - 3.4e-05 23.3 0.0 0.00042 19.7 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EGE07550.1 - 3.7e-05 23.1 0.0 0.00077 18.8 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EGE07550.1 - 0.00026 20.6 0.0 0.0049 16.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain PPP1R26_N PF15740.5 EGE07550.1 - 0.0016 17.2 4.0 0.0021 16.8 4.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 26 N-terminus PrmA PF06325.13 EGE07550.1 - 0.011 15.2 0.4 0.017 14.5 0.0 1.6 2 0 0 2 2 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EGE07550.1 - 0.017 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGE07550.1 - 0.019 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 EGE07550.1 - 0.034 13.6 1.0 0.22 11.0 0.0 2.5 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_PK PF05891.12 EGE07550.1 - 0.13 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase LRR19-TM PF15176.6 EGE07550.1 - 0.5 10.4 4.0 1 9.4 4.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Paf1 PF03985.13 EGE07550.1 - 3.3 6.6 15.3 4.8 6.1 15.3 1.1 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 EGE07550.1 - 3.8 7.4 23.2 4.7 7.1 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prp19 PF08606.11 EGE07552.1 - 3.3e-33 113.5 1.2 6.3e-33 112.6 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EGE07552.1 - 3.7e-14 52.8 0.1 4e-07 30.2 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE07552.1 - 1.3e-09 38.5 11.7 3e-05 24.7 0.0 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGE07552.1 - 2.6e-09 36.6 0.3 0.00026 20.2 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.11 EGE07552.1 - 2.2e-05 24.4 0.0 0.044 13.7 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 EGE07552.1 - 0.0004 20.7 0.1 0.0009 19.6 0.1 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain Cytochrom_D1 PF02239.16 EGE07552.1 - 0.00081 18.0 0.6 0.18 10.3 0.1 2.2 1 1 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EGE07552.1 - 0.0018 17.6 0.0 0.79 9.0 0.0 2.5 1 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGE07552.1 - 0.013 14.5 0.1 0.037 13.0 0.1 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EGE07552.1 - 0.097 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Frtz PF11768.8 EGE07552.1 - 0.14 10.4 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz GTP_EFTU PF00009.27 EGE07553.1 - 2.2e-57 193.7 0.1 5.1e-57 192.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGE07553.1 - 4.7e-15 55.4 0.0 1.1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGE07553.1 - 4.3e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGE07553.1 - 1e-06 29.1 0.0 3.1e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGE07553.1 - 0.00011 21.9 0.0 0.00096 18.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EGE07553.1 - 0.065 13.3 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase EXOSC1 PF10447.9 EGE07554.1 - 7.4e-28 97.3 4.5 1.1e-27 96.8 4.5 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGE07554.1 - 2.6e-12 46.3 0.1 4.5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 EGE07554.1 - 0.089 13.5 1.1 0.75 10.6 1.0 2.2 1 1 1 2 2 2 0 Penicillin-binding protein OB-like domain Arm PF00514.23 EGE07555.1 - 5.1e-70 229.6 28.1 3.6e-11 42.7 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGE07555.1 - 9.5e-17 61.1 19.7 5.4e-05 23.6 0.2 7.6 6 3 3 9 9 8 5 HEAT-like repeat HEAT PF02985.22 EGE07555.1 - 1e-14 53.4 16.2 0.18 12.1 0.1 9.0 10 0 0 10 10 9 4 HEAT repeat HEAT_2 PF13646.6 EGE07555.1 - 1.7e-14 54.0 13.5 0.00016 22.0 0.1 6.9 3 3 3 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 EGE07555.1 - 3.6e-13 48.9 6.7 8.3e-08 31.2 0.2 2.6 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EGE07555.1 - 3e-09 36.7 5.2 1.2e-05 24.9 2.2 2.5 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 EGE07555.1 - 3.4e-09 35.5 0.5 9e-09 34.0 0.2 1.7 1 1 1 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EGE07555.1 - 3.9e-08 32.9 0.7 0.0006 19.2 0.9 2.8 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EGE07555.1 - 0.0003 20.9 6.2 0.041 13.9 0.6 4.4 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 EGE07555.1 - 0.00071 19.1 8.8 0.43 10.0 0.0 4.7 1 1 3 5 5 5 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 EGE07555.1 - 0.00073 19.5 2.7 1.7 8.7 0.0 4.7 4 1 1 5 5 5 1 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EGE07555.1 - 0.0017 18.8 8.7 1.2 10.0 0.5 6.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EGE07555.1 - 0.002 18.2 2.1 31 4.7 0.0 4.9 2 1 5 7 7 7 0 V-ATPase subunit H DUF3361 PF11841.8 EGE07555.1 - 0.0021 18.0 6.6 1.3 9.0 0.0 4.2 2 1 3 5 5 5 1 Domain of unknown function (DUF3361) UNC45-central PF11701.8 EGE07555.1 - 0.012 15.5 1.4 1.3 9.0 0.1 3.1 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EGE07555.1 - 0.033 14.8 0.1 0.67 10.6 0.1 2.9 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region FHA PF00498.26 EGE07557.1 - 2.4e-14 53.4 0.0 5.1e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EGE07557.1 - 2.7e-10 39.8 4.2 5.1e-10 38.9 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGE07557.1 - 8.3e-07 29.2 8.8 1.6e-06 28.4 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EGE07557.1 - 0.00034 20.9 0.0 0.00079 19.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EGE07557.1 - 0.0013 18.6 6.7 0.0025 17.7 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE07557.1 - 0.012 15.4 8.1 0.023 14.5 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE07557.1 - 0.018 14.8 8.7 0.036 13.9 8.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EGE07557.1 - 0.021 15.2 5.5 0.047 14.0 5.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 EGE07557.1 - 0.05 13.6 2.9 0.1 12.6 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGE07557.1 - 0.14 12.4 8.2 0.4 11.0 8.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 EGE07557.1 - 0.21 11.5 5.6 0.42 10.5 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-H2C2_2 PF13465.6 EGE07557.1 - 1.8 9.1 3.6 1.4 9.4 0.8 2.4 2 0 0 2 2 1 0 Zinc-finger double domain Zn_ribbon_17 PF17120.5 EGE07557.1 - 3.9 7.2 8.1 8 6.2 8.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EGE07557.1 - 4.5 7.5 7.2 7.5 6.8 6.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING TFIIA PF03153.13 EGE07557.1 - 5.4 6.9 25.6 0.094 12.7 4.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Bestrophin PF01062.21 EGE07558.1 - 7.2e-58 196.3 0.0 9.2e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel IGF2_C PF08365.11 EGE07559.1 - 1.7 8.7 5.3 24 5.0 0.5 3.3 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide AAA_lid_2 PF17863.1 EGE07560.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain Vps16_N PF04841.13 EGE07561.1 - 1.7e-98 330.1 0.0 2.6e-98 329.5 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EGE07561.1 - 2e-73 247.2 0.3 3.1e-73 246.6 0.3 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EGE07561.1 - 2.5e-05 24.5 0.0 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Alb1 PF09135.11 EGE07562.1 - 1.8e-31 109.1 10.7 2.9e-31 108.4 10.7 1.3 1 0 0 1 1 1 1 Alb1 CTX_RstB PF07459.11 EGE07562.1 - 0.13 12.5 0.2 0.31 11.3 0.2 1.6 1 1 0 1 1 1 0 CTX phage RstB protein UCH PF00443.29 EGE07563.1 - 3.9e-29 101.9 0.0 1.9e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07563.1 - 1.2e-07 31.7 1.9 1.3e-05 25.0 1.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_9 PF14658.6 EGE07564.1 - 0.0016 18.7 0.0 0.77 10.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGE07564.1 - 0.038 13.9 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Dak2 PF02734.17 EGE07564.1 - 0.074 13.0 0.0 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 DAK2 domain PUL PF08324.11 EGE07565.1 - 2.4e-27 95.9 0.5 2.6e-27 95.8 0.5 1.0 1 0 0 1 1 1 1 PUL domain Kinesin PF00225.23 EGE07566.1 - 6.9e-63 212.6 0.1 8.6e-36 123.5 0.0 2.4 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGE07566.1 - 1.7e-23 83.2 1.6 2e-23 83.0 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding DUF1460 PF07313.12 EGE07566.1 - 0.038 13.4 1.3 0.064 12.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Spc7 PF08317.11 EGE07566.1 - 0.066 12.1 10.6 0.13 11.2 10.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5094 PF17015.5 EGE07566.1 - 0.078 13.1 5.9 0.17 12.0 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) IL11 PF07400.11 EGE07566.1 - 0.43 10.2 5.3 26 4.4 4.6 2.7 2 1 0 2 2 2 0 Interleukin 11 DUF87 PF01935.17 EGE07566.1 - 0.66 10.0 0.0 0.66 10.0 0.0 2.6 2 1 0 2 2 2 0 Helicase HerA, central domain FUSC PF04632.12 EGE07566.1 - 0.86 8.1 5.0 1.3 7.5 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAM76 PF16046.5 EGE07566.1 - 1.3 8.3 5.6 2.2 7.5 5.6 1.4 1 0 0 1 1 1 0 FAM76 protein DUF1043 PF06295.12 EGE07566.1 - 1.5 8.8 7.2 3.9 7.5 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) YabA PF06156.13 EGE07566.1 - 1.7 9.3 13.2 20 5.9 7.3 3.0 3 1 0 3 3 3 0 Initiation control protein YabA MCU PF04678.13 EGE07566.1 - 6.7 6.8 7.9 13 5.8 7.9 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter IF-2B PF01008.17 EGE07567.1 - 5.9e-70 235.7 0.1 7.6e-70 235.3 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Apc13p PF05839.11 EGE07568.1 - 9.4e-21 73.8 1.1 2.2e-17 63.0 0.1 2.2 1 1 1 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.10 EGE07569.1 - 3e-79 266.5 0.4 3.8e-79 266.1 0.4 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EGE07569.1 - 2.2e-34 118.6 0.0 3.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.20 EGE07570.1 - 1.8e-36 125.3 0.0 2.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGE07570.1 - 5.6e-14 52.1 0.0 1.4e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGE07570.1 - 0.0005 20.3 0.0 0.00073 19.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CBS PF00571.28 EGE07571.1 - 3.8e-20 72.1 6.4 1.2e-08 35.3 0.4 4.2 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 EGE07572.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RhoGAP domain ECH_2 PF16113.5 EGE07573.1 - 1.2e-130 435.9 0.0 1.5e-130 435.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGE07573.1 - 2.1e-27 96.0 0.0 1.5e-26 93.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Ribosomal_L4 PF00573.22 EGE07574.1 - 4.5e-46 157.0 0.0 7.1e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Sde2_N_Ubi PF13019.6 EGE07574.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain PBP PF01161.20 EGE07575.1 - 2.8e-06 27.7 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ABC_tran_Xtn PF12848.7 EGE07575.1 - 0.36 10.9 6.1 0.9 9.6 6.1 1.6 1 0 0 1 1 1 0 ABC transporter Peptidase_S24 PF00717.23 EGE07576.1 - 4.5e-09 36.1 0.1 7.7e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGE07576.1 - 0.00037 20.3 0.0 0.01 15.6 0.0 2.3 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 HAGH_C PF16123.5 EGE07577.1 - 6.8e-21 74.6 0.9 1e-20 74.0 0.9 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGE07577.1 - 3.6e-17 63.0 5.6 3.1e-16 60.0 5.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGE07577.1 - 0.012 15.2 4.4 0.14 11.6 4.2 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 EGE07577.1 - 0.038 13.5 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.13 EGE07578.1 - 1.5e-17 64.1 0.0 3.1e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Las1-like tRNA_synt_1c_R2 PF04557.15 EGE07580.1 - 1.2 10.1 12.5 5.3 8.0 4.3 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 OAD_gamma PF04277.13 EGE07580.1 - 1.3 9.7 4.9 12 6.6 1.1 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain SR-25 PF10500.9 EGE07580.1 - 1.5 8.4 32.9 3.3 7.3 32.9 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Menin PF05053.13 EGE07580.1 - 2 6.7 6.6 2.3 6.5 6.6 1.0 1 0 0 1 1 1 0 Menin NAD_kinase PF01513.21 EGE07583.1 - 1.8e-74 250.6 0.0 2.3e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.16 EGE07584.1 - 5.5e-39 133.2 0.0 7.7e-39 132.7 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MFAP1 PF06991.11 EGE07585.1 - 6.7e-67 225.5 17.4 6.7e-67 225.5 17.4 3.1 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Glyco_hydro_16 PF00722.21 EGE07586.1 - 2.1e-45 154.3 2.1 3.2e-45 153.7 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rep_fac-A_3 PF08661.11 EGE07587.1 - 2e-22 79.5 0.0 2.3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.27 EGE07588.1 - 1.1e-05 24.9 3.4 0.0011 18.5 0.3 2.6 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 EGE07588.1 - 0.2 11.8 1.6 0.39 10.9 0.7 2.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain LSM PF01423.22 EGE07589.1 - 1.1e-14 53.9 0.4 1e-13 50.7 0.4 2.0 1 1 0 1 1 1 1 LSM domain Dak1 PF02733.17 EGE07590.1 - 6.1e-106 353.8 1.9 8.6e-106 353.3 1.9 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGE07590.1 - 1e-48 165.5 0.5 4.6e-48 163.4 0.4 2.0 2 0 0 2 2 2 1 DAK2 domain Nuc_deoxyrib_tr PF05014.15 EGE07590.1 - 0.2 11.6 0.3 0.51 10.4 0.1 1.7 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Cullin PF00888.22 EGE07591.1 - 5.1e-159 530.8 1.4 1.7e-99 334.1 0.0 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EGE07591.1 - 7e-25 86.9 1.4 2.1e-24 85.3 1.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 EGE07591.1 - 0.006 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 HbrB-like Nup192 PF11894.8 EGE07592.1 - 0 1185.3 14.0 0 1160.5 11.9 2.0 1 1 1 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 PI3_PI4_kinase PF00454.27 EGE07593.1 - 2.5e-49 168.4 1.9 2.6e-49 168.3 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EGE07593.1 - 4.6e-45 153.4 0.1 1.6e-44 151.6 0.1 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EGE07593.1 - 1e-11 44.5 0.1 2.3e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EGE07593.1 - 4.7e-07 29.4 3.8 1e-06 28.2 3.8 1.5 1 0 0 1 1 1 1 FAT domain UPF0052 PF01933.18 EGE07594.1 - 2.3e-58 197.8 0.0 3.2e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_2 PF13923.6 EGE07595.1 - 5.2e-09 35.8 7.5 8.6e-09 35.1 3.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE07595.1 - 6.9e-09 35.4 4.2 2e-08 33.9 4.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE07595.1 - 4.7e-08 33.2 4.6 7.4e-08 32.6 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGE07595.1 - 5.8e-08 32.6 6.0 2.9e-07 30.4 1.8 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGE07595.1 - 1.4e-07 31.2 8.4 4.2e-07 29.7 8.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE07595.1 - 8.5e-07 28.8 5.2 1.6e-06 28.0 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGE07595.1 - 3.2e-06 27.2 6.4 3.1e-05 24.0 7.0 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGE07595.1 - 8.3e-05 22.4 6.6 0.00041 20.1 6.7 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 RNHCP PF12647.7 EGE07595.1 - 0.043 13.8 1.5 8.9 6.4 0.1 2.4 1 1 1 2 2 2 0 RNHCP domain zf-Nse PF11789.8 EGE07595.1 - 0.049 13.5 1.3 0.11 12.3 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 EGE07595.1 - 0.11 12.4 0.9 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 EGE07595.1 - 0.15 12.3 5.6 0.5 10.7 5.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 EGE07595.1 - 0.15 12.2 3.0 0.73 10.1 3.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain DUF1644 PF07800.12 EGE07595.1 - 0.33 11.0 6.1 0.92 9.6 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-ANAPC11 PF12861.7 EGE07595.1 - 0.33 11.0 3.5 2 8.5 3.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGE07595.1 - 0.58 10.1 4.3 0.48 10.3 1.4 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGE07595.1 - 3.4 7.5 7.2 18 5.2 7.2 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DNApol_Exo PF18136.1 EGE07596.1 - 1.2e-104 349.5 0.1 2e-104 348.7 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EGE07596.1 - 2.1e-27 96.2 0.0 3.9e-25 88.7 0.0 2.3 1 1 0 2 2 2 2 DNA polymerase family A TFIIS_M PF07500.14 EGE07596.1 - 0.023 15.2 0.9 0.09 13.3 0.9 2.0 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain DNA_pol_A_exo1 PF01612.20 EGE07596.1 - 0.031 14.0 0.1 0.61 9.8 0.1 2.4 1 1 0 1 1 1 0 3'-5' exonuclease Mad3_BUB1_I PF08311.12 EGE07596.1 - 0.089 12.8 0.2 0.22 11.5 0.2 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 CorA PF01544.18 EGE07597.1 - 7.7e-24 84.5 6.3 2.2e-16 60.0 1.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.19 EGE07598.1 - 1.9e-50 171.8 0.0 3.4e-50 171.0 0.0 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase Soyouz_module PF14313.6 EGE07598.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SNF2_N PF00176.23 EGE07599.1 - 1.5e-65 221.3 0.0 9.3e-64 215.3 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EGE07599.1 - 8e-25 86.6 0.0 1.6e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EGE07599.1 - 4e-13 49.7 0.0 1e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE07599.1 - 1.5e-07 31.6 0.0 3.5e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EGE07599.1 - 0.0012 18.7 5.0 0.0028 17.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE07599.1 - 0.0017 18.1 12.6 0.0039 17.0 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE07599.1 - 0.0035 17.2 12.7 0.0067 16.3 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE07599.1 - 0.0081 16.2 11.3 0.022 14.8 11.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGE07599.1 - 0.057 13.4 11.0 0.13 12.2 11.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGE07599.1 - 0.084 13.2 13.3 0.1 12.9 11.9 2.0 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EGE07599.1 - 0.65 10.2 12.4 1.4 9.1 12.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGE07599.1 - 4.5 7.2 14.2 27 4.7 14.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Lyase_1 PF00206.20 EGE07600.1 - 5e-22 78.7 0.1 9.1e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EGE07600.1 - 3.2e-17 62.8 0.0 9.3e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GTP_EFTU PF00009.27 EGE07602.1 - 7.6e-20 71.3 0.1 2.9e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGE07602.1 - 4.8e-07 30.1 1.0 3.1e-06 27.5 0.7 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGE07602.1 - 3.7e-05 24.0 0.0 9.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGE07602.1 - 0.0023 18.0 0.1 0.0059 16.7 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE07602.1 - 0.0051 16.7 0.2 3.9 7.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EGE07602.1 - 0.0073 16.1 0.4 3.3 7.5 0.0 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EGE07602.1 - 0.053 13.7 0.2 1 9.6 0.1 2.5 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGE07602.1 - 0.062 13.4 0.7 0.36 10.9 0.1 2.3 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EGE07602.1 - 0.093 12.1 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family LSM PF01423.22 EGE07603.1 - 4.1e-18 64.8 0.2 5.3e-18 64.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 EGE07604.1 - 5.6e-27 93.9 0.0 1.2e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EGE07604.1 - 1.4e-07 31.5 0.0 7.4e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EGE07604.1 - 9.6e-06 25.7 0.1 0.15 12.3 0.1 3.3 4 0 0 4 4 4 2 PPR repeat family Csc2 PF18320.1 EGE07604.1 - 0.0059 15.6 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Csc2 Crispr FCD PF07729.12 EGE07604.1 - 0.0086 16.5 0.7 0.018 15.5 0.7 1.5 1 0 0 1 1 1 1 FCD domain PPR PF01535.20 EGE07604.1 - 0.026 14.8 0.3 8.7 6.8 0.1 3.5 3 0 0 3 3 3 0 PPR repeat DUF1216 PF06746.11 EGE07604.1 - 0.13 12.3 1.0 0.29 11.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) PIG-L PF02585.17 EGE07605.1 - 2.4e-28 99.4 0.0 3.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DnaJ PF00226.31 EGE07607.1 - 4.7e-15 55.5 0.1 1.1e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 EGE07607.1 - 0.02 14.7 0.3 0.062 13.1 0.3 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mei4 PF13971.6 EGE07608.1 - 0.0032 17.1 0.1 0.0059 16.2 0.1 1.4 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 GCV_T PF01571.21 EGE07609.1 - 7.7e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DCP2 PF05026.13 EGE07611.1 - 2.8e-31 107.7 1.4 5.1e-31 106.8 1.4 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EGE07611.1 - 4.7e-17 62.2 0.1 8.7e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 EGE07612.1 - 9e-23 80.6 0.1 1.2e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AgrD PF05931.11 EGE07612.1 - 0.059 13.4 0.3 0.12 12.4 0.3 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein MotB_plug PF13677.6 EGE07612.1 - 0.11 12.1 0.7 0.22 11.2 0.7 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB CTU2 PF10288.9 EGE07613.1 - 8.5e-10 38.9 0.3 8.5e-10 38.9 0.3 2.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Lung_7-TM_R PF06814.13 EGE07614.1 - 6.8e-63 212.6 18.4 8.8e-63 212.3 18.4 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 EGE07614.1 - 1.8 8.4 4.6 1.8 8.4 0.2 2.4 2 0 0 2 2 2 0 SurA N-terminal domain DUF1308 PF07000.11 EGE07615.1 - 1.4e-14 54.3 0.0 9.6e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF2408 PF10303.9 EGE07615.1 - 0.16 12.6 1.6 0.34 11.5 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) WD40 PF00400.32 EGE07616.1 - 7.3e-13 48.8 0.9 0.0002 22.1 0.1 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE07616.1 - 5.6e-06 26.6 0.0 0.0029 17.9 0.0 3.6 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.11 EGE07616.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Frtz PF11768.8 EGE07616.1 - 0.23 9.7 0.0 0.44 8.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Mito_carr PF00153.27 EGE07617.1 - 8e-52 173.1 3.1 9.1e-17 60.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.21 EGE07618.1 - 1.6e-103 346.0 2.2 2e-103 345.7 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 EGE07619.1 - 4.4e-33 113.5 1.5 5.8e-33 113.2 1.5 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) K_channel_TID PF07941.11 EGE07619.1 - 0.026 15.0 1.6 1.4 9.4 0.2 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.32 EGE07620.1 - 1.1e-25 89.3 3.1 7.9e-05 23.4 0.2 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE07620.1 - 7e-07 29.5 0.1 2.7 8.4 0.1 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGE07620.1 - 0.0024 16.4 0.0 0.067 11.7 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 EGE07620.1 - 0.008 14.9 0.1 0.31 9.7 0.2 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGE07620.1 - 0.014 14.3 0.0 1.3 7.9 0.0 2.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CBM_19 PF03427.13 EGE07620.1 - 0.28 11.2 0.0 0.28 11.2 0.0 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) Nudix_N_2 PF14803.6 EGE07620.1 - 1.3 9.0 4.5 13 5.8 5.6 2.1 2 0 0 2 2 2 0 Nudix N-terminal OHCU_decarbox PF09349.10 EGE07621.1 - 6.3e-45 153.4 0.1 7.3e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF3684 PF12449.8 EGE07621.1 - 0.028 12.2 0.0 0.051 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3684) SPATIAL PF15256.6 EGE07623.1 - 1.1 9.6 7.8 3 8.1 0.1 2.2 2 0 0 2 2 2 0 SPATIAL Peptidase_S49_N PF08496.10 EGE07623.1 - 2.2 8.3 8.5 3.6 7.6 8.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DNMT1-RFD PF12047.8 EGE07626.1 - 0.00068 19.7 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain TetR_C_15 PF17918.1 EGE07634.1 - 0.27 12.0 4.0 0.66 10.8 4.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Amino_oxidase PF01593.24 EGE07635.1 - 2e-65 221.9 0.1 3e-65 221.3 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE07635.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 EGE07636.1 - 4.3e-23 81.8 0.0 6.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07636.1 - 3.9e-21 75.7 0.0 5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE07636.1 - 0.00019 21.4 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain MlaE PF02405.16 EGE07636.1 - 0.053 13.2 0.1 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Permease MlaE DUF1776 PF08643.10 EGE07636.1 - 0.061 12.7 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGE07636.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 EGE07637.1 - 1.2e-33 116.6 22.8 1.2e-33 116.6 22.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EGE07642.1 - 1.4e-40 139.4 0.1 4.1e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE07642.1 - 9.4e-05 22.5 5.4 0.00021 21.3 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 EGE07644.1 - 1.1e-47 161.9 0.3 6.3e-26 91.5 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EGE07644.1 - 3.3e-28 99.1 37.3 2.5e-23 83.1 16.7 2.8 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EGE07644.1 - 2.1e-09 37.7 6.0 0.012 15.5 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE07644.1 - 6.2e-09 35.6 5.7 0.0024 17.3 0.1 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGE07644.1 - 9.3e-07 29.5 0.4 0.0011 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE07644.1 - 1.8e-06 28.0 0.5 0.0014 18.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGE07644.1 - 2e-06 27.5 0.7 0.011 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE07644.1 - 1.8e-05 25.2 0.4 0.054 13.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGE07644.1 - 7.1e-05 22.9 0.2 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_19 PF13245.6 EGE07644.1 - 0.00036 20.9 0.0 0.05 13.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGE07644.1 - 0.00038 20.2 0.1 5.6 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EGE07644.1 - 0.00043 20.7 0.5 0.11 13.0 0.0 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EGE07644.1 - 0.00086 19.4 0.1 0.036 14.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EGE07644.1 - 0.0012 19.1 3.8 0.28 11.5 0.4 3.0 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 EGE07644.1 - 0.0027 17.5 1.0 0.041 13.6 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGE07644.1 - 0.0039 17.0 0.8 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EGE07644.1 - 0.006 15.8 1.0 0.82 8.8 0.5 2.7 2 1 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EGE07644.1 - 0.0069 16.3 0.1 0.48 10.3 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGE07644.1 - 0.011 14.9 0.2 1 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EGE07644.1 - 0.013 15.0 0.3 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EGE07644.1 - 0.016 14.2 0.5 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EGE07644.1 - 0.018 15.4 0.2 2.3 8.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_30 PF13604.6 EGE07644.1 - 0.02 14.7 0.1 2.6 7.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGE07644.1 - 0.022 14.5 4.2 13 5.5 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein MeaB PF03308.16 EGE07644.1 - 0.044 12.8 0.9 1.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_10 PF12846.7 EGE07644.1 - 0.049 12.5 1.0 4.6 6.1 0.1 2.5 2 1 0 2 2 2 0 AAA-like domain Adeno_IVa2 PF02456.15 EGE07644.1 - 0.057 12.2 0.2 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 EGE07644.1 - 0.062 12.6 0.1 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EGE07644.1 - 0.088 12.7 2.8 7 6.5 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 EGE07644.1 - 0.097 12.7 0.2 0.66 10.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.9 EGE07644.1 - 0.16 10.7 3.1 1.4 7.6 0.1 3.0 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 EGE07644.1 - 0.16 12.5 0.1 8.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGE07644.1 - 0.22 11.1 0.4 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGE07644.1 - 0.23 11.4 3.4 0.96 9.3 0.0 3.1 3 0 0 3 3 2 0 NACHT domain Roc PF08477.13 EGE07644.1 - 0.24 11.6 0.4 64 3.8 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EGE07644.1 - 0.45 10.1 7.1 0.38 10.3 0.8 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGE07644.1 - 0.49 10.5 1.4 7.5 6.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EGE07644.1 - 0.84 9.7 3.8 1.9 8.5 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 EGE07644.1 - 1.9 8.3 5.4 1 9.3 0.3 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Condensation PF00668.20 EGE07648.1 - 0 1307.8 0.0 1.2e-55 189.0 0.0 11.1 10 3 0 10 10 10 10 Condensation domain AMP-binding PF00501.28 EGE07648.1 - 0 1304.1 0.0 2e-82 277.1 0.0 5.2 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 EGE07648.1 - 5.4e-74 244.5 6.7 3.3e-11 43.4 0.3 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EGE07648.1 - 7.9e-14 52.4 0.1 0.00089 20.2 0.0 5.8 5 0 0 5 5 5 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EGE07648.1 - 2e-11 43.2 0.2 0.0014 17.4 0.0 5.9 7 0 0 7 7 7 4 Transferase family DUF5122 PF17164.4 EGE07648.1 - 0.34 11.2 1.5 21 5.5 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller GMP_synt_C PF00958.22 EGE07650.1 - 2.6e-42 142.8 0.0 5.1e-42 141.9 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EGE07650.1 - 1.3e-38 132.7 0.0 2.2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EGE07650.1 - 1.7e-10 40.4 0.1 2.6e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EGE07650.1 - 3.6e-07 30.2 0.1 6.3e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.13 EGE07650.1 - 0.0011 18.5 0.0 0.0084 15.6 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EGE07650.1 - 0.0029 16.4 0.1 0.007 15.2 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 EGE07650.1 - 0.0074 15.9 0.1 0.017 14.7 0.1 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EGE07650.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 EGE07650.1 - 0.059 13.4 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EGE07650.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family BCIP PF13862.6 EGE07651.1 - 3.7e-74 249.0 0.1 4.7e-74 248.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein VID27_N PF17748.1 EGE07651.1 - 0.069 13.0 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 VID27 N-terminal region WD40 PF00400.32 EGE07653.1 - 2e-28 98.0 11.1 6.9e-07 29.9 0.5 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EGE07653.1 - 1.6e-06 27.1 2.3 0.094 11.3 0.1 4.9 4 1 1 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGE07653.1 - 2.7e-05 24.4 0.0 0.16 12.3 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 EGE07653.1 - 0.0082 16.2 3.1 0.014 15.4 3.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EGE07653.1 - 0.015 15.5 0.5 0.031 14.5 0.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EGE07653.1 - 0.025 15.1 1.8 0.054 14.0 1.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EGE07653.1 - 0.037 13.3 0.7 0.068 12.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EzrA PF06160.12 EGE07653.1 - 0.041 12.1 0.2 0.06 11.5 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BBS2_Mid PF14783.6 EGE07653.1 - 0.078 13.0 0.1 1.3 9.1 0.0 3.1 6 0 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region RasGAP_C PF03836.15 EGE07653.1 - 0.097 12.8 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 RasGAP C-terminus DUF5046 PF16465.5 EGE07653.1 - 0.14 11.6 0.2 0.79 9.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) PI3K_P85_iSH2 PF16454.5 EGE07653.1 - 0.16 11.6 1.4 0.36 10.4 1.3 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 EGE07653.1 - 0.25 11.4 2.7 1 9.4 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 EGE07653.1 - 0.72 10.2 4.8 9 6.7 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Sad1_UNC PF07738.13 EGE07654.1 - 3e-08 33.7 0.0 5.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SUIM_assoc PF16619.5 EGE07654.1 - 0.025 14.7 4.4 0.025 14.7 4.4 3.8 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 EGE07654.1 - 1.3 8.9 15.0 1.7 8.6 3.3 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Kinesin PF00225.23 EGE07655.1 - 5e-89 298.5 4.4 1.3e-88 297.2 0.0 3.1 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGE07655.1 - 7.7e-19 68.1 0.0 3e-15 56.4 0.0 3.5 3 0 0 3 3 3 2 Microtubule binding SHE3 PF17078.5 EGE07655.1 - 0.0028 17.4 19.5 0.0028 17.4 19.5 8.8 5 2 3 9 9 9 2 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 EGE07655.1 - 0.0084 16.6 14.8 0.0084 16.6 14.8 12.5 4 3 6 12 12 12 3 Apg6 coiled-coil region Glycos_transf_1 PF00534.20 EGE07656.1 - 6.4e-31 107.2 0.0 5.1e-29 101.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGE07656.1 - 8.6e-19 68.2 0.1 1.8e-18 67.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGE07656.1 - 1.3e-13 51.5 0.0 8.4e-13 48.9 0.0 2.3 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGE07656.1 - 2.3e-08 34.6 0.4 4e-08 33.9 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGE07656.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EGE07656.1 - 0.024 14.7 0.0 5.9 6.9 0.0 2.4 2 0 0 2 2 2 0 ALG11 mannosyltransferase N-terminus Peptidase_M19 PF01244.21 EGE07657.1 - 1.1e-107 359.9 0.0 1.3e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GST_C PF00043.25 EGE07659.1 - 2.9e-15 56.3 0.0 5.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGE07659.1 - 2.2e-10 40.8 0.0 4.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGE07659.1 - 5.5e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE07659.1 - 1.8e-09 37.8 0.0 3.6e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE07659.1 - 3.5e-09 36.8 0.0 6.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE07659.1 - 4.4e-08 33.0 0.0 8.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aldedh PF00171.22 EGE07660.1 - 2.8e-185 616.3 0.2 3.1e-185 616.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGE07660.1 - 0.18 11.2 0.0 16 4.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Metallophos PF00149.28 EGE07661.1 - 6.2e-32 111.8 0.0 1.4e-27 97.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGE07661.1 - 0.0023 17.6 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DIOX_N PF14226.6 EGE07662.1 - 1.7e-09 38.4 0.0 3.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE07662.1 - 1.1e-06 29.0 0.0 6.1e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ctr PF04145.15 EGE07663.1 - 9.7e-41 139.8 0.1 1.2e-40 139.5 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TraL PF07178.11 EGE07663.1 - 0.48 10.9 2.9 15 6.1 0.3 2.2 2 0 0 2 2 2 0 TraL protein Smg4_UPF3 PF03467.15 EGE07664.1 - 6.6e-41 140.2 0.0 6.6e-41 140.2 0.0 3.1 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 EGE07664.1 - 0.0019 18.0 0.0 0.053 13.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AbiJ_NTD3 PF18860.1 EGE07664.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AbiJ N-terminal domain 3 zf-C2H2 PF00096.26 EGE07666.1 - 1.4e-11 44.2 11.8 4.8e-06 26.7 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE07666.1 - 4.7e-08 33.2 9.3 0.00038 21.1 0.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE07666.1 - 5.2e-07 29.8 8.4 2.1e-05 24.7 2.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EGE07666.1 - 0.00071 19.8 8.6 0.014 15.7 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EGE07666.1 - 0.0014 18.6 5.6 0.52 10.4 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGE07666.1 - 0.0072 16.1 0.2 0.0072 16.1 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2HE PF16278.5 EGE07666.1 - 0.046 14.2 8.5 1.1 9.8 0.9 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EGE07666.1 - 0.05 14.0 11.8 0.4 11.1 0.2 3.2 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGE07666.1 - 0.33 10.7 3.2 5.7 6.8 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EGE07666.1 - 0.64 10.1 4.3 0.38 10.8 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger BolA PF01722.18 EGE07666.1 - 4.3 7.7 6.6 1.1 9.6 0.1 2.7 2 1 1 3 3 3 0 BolA-like protein p450 PF00067.22 EGE07669.1 - 2.1e-59 201.5 0.0 5.9e-58 196.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DivIC PF04977.15 EGE07670.1 - 0.029 14.1 0.1 0.029 14.1 0.1 2.0 3 0 0 3 3 3 0 Septum formation initiator GATA PF00320.27 EGE07671.1 - 5.9e-15 54.6 1.3 1e-14 53.8 1.3 1.4 1 0 0 1 1 1 1 GATA zinc finger SUIM_assoc PF16619.5 EGE07671.1 - 0.00063 19.8 3.1 0.00063 19.8 3.1 3.5 4 0 0 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 TF_Zn_Ribbon PF08271.12 EGE07671.1 - 0.098 12.2 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EGE07671.1 - 0.24 11.6 0.2 0.37 11.0 0.2 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-3c_N PF05470.12 EGE07672.1 - 0.14 10.4 1.7 0.16 10.3 1.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EGE07672.1 - 0.8 7.9 7.1 0.86 7.8 7.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 EGE07674.1 - 5.6e-08 32.8 6.6 8e-08 32.3 6.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H PF00075.24 EGE07676.1 - 4.8e-07 30.0 0.1 3.2e-06 27.4 0.0 2.3 1 1 1 2 2 2 1 RNase H DUF1351 PF07083.11 EGE07676.1 - 0.025 14.4 5.7 0.061 13.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) Lipoprotein_10 PF03202.13 EGE07676.1 - 0.041 14.3 0.9 0.12 12.8 0.1 2.3 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region Glyco_trans_4_2 PF13477.6 EGE07676.1 - 0.053 13.5 0.4 0.64 10.0 0.1 2.4 2 1 0 2 2 2 0 Glycosyl transferase 4-like zf-RVT PF13966.6 EGE07676.1 - 0.2 12.4 3.5 3.2 8.5 3.5 2.6 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase WW PF00397.26 EGE07679.1 - 1.8e-06 27.9 0.4 4.2e-06 26.8 0.4 1.7 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 EGE07679.1 - 0.043 13.8 8.5 0.054 13.5 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobD_Cbib PF03186.13 EGE07679.1 - 0.12 11.6 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Cu-oxidase_3 PF07732.15 EGE07680.1 - 2.4e-44 150.1 0.9 2.7e-42 143.6 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EGE07680.1 - 8.3e-36 122.7 8.8 6.1e-35 119.9 2.8 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE07680.1 - 1.7e-14 54.2 0.0 2.3e-12 47.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.14 EGE07682.1 - 1.9e-71 241.1 0.7 2.8e-71 240.6 0.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family F-box PF00646.33 EGE07684.1 - 0.0017 18.2 0.3 0.042 13.7 0.0 2.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EGE07684.1 - 0.14 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 F-box ZZ PF00569.17 EGE07685.1 - 6.3e-15 54.7 26.6 3.9e-10 39.4 10.8 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type HET PF06985.11 EGE07685.1 - 8.6e-13 48.9 7.1 1.2e-10 41.9 1.9 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) C1_2 PF03107.16 EGE07685.1 - 2.4e-09 37.4 23.2 0.00015 22.0 3.8 2.5 2 0 0 2 2 2 2 C1 domain Methyltransf_23 PF13489.6 EGE07686.1 - 4.4e-05 23.4 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07686.1 - 7.9e-05 23.3 0.0 0.00018 22.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07686.1 - 0.00019 22.0 0.0 0.00035 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07686.1 - 0.0044 16.8 0.0 0.0095 15.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07686.1 - 0.0083 16.8 0.0 0.016 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGE07686.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB CheR PF01739.18 EGE07686.1 - 0.049 13.1 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Rrn6 PF10214.9 EGE07688.1 - 2.3 6.6 10.1 2.3 6.6 10.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Opy2 PF09463.10 EGE07689.1 - 1.6e-09 37.9 19.9 2.7e-09 37.2 19.9 1.4 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 EGE07689.1 - 2.7e-05 23.5 0.3 2.7e-05 23.5 0.3 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Beta-APP PF03494.13 EGE07689.1 - 0.067 13.1 1.4 0.13 12.1 1.4 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Dicty_REP PF05086.12 EGE07689.1 - 0.24 9.3 9.7 0.31 9.0 9.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 EGE07689.1 - 0.41 10.6 10.1 4.5 7.3 9.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tmemb_cc2 PF10267.9 EGE07689.1 - 0.86 8.7 9.5 1.3 8.1 9.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF5401 PF17380.2 EGE07689.1 - 6.2 4.8 14.3 8.5 4.3 14.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AMP-binding PF00501.28 EGE07690.1 - 1.5e-46 158.9 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE07690.1 - 0.099 13.6 0.1 0.2 12.7 0.1 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Chitin_synth_1 PF01644.17 EGE07691.1 - 1.9e-56 190.5 0.0 3e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EGE07691.1 - 7.3e-23 81.0 0.1 3.1e-18 65.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 EGE07691.1 - 6.8e-16 58.0 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EGE07691.1 - 5.6e-09 36.2 0.1 5.6e-09 36.2 0.1 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 UQ_con PF00179.26 EGE07692.1 - 8.9e-36 122.6 0.0 1.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE07692.1 - 0.092 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B COX6C PF02937.15 EGE07693.1 - 0.048 13.8 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc TAF8_C PF10406.9 EGE07694.1 - 9.7e-21 74.1 0.6 3e-20 72.5 0.6 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EGE07694.1 - 1.1e-05 25.4 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Dicty_REP PF05086.12 EGE07694.1 - 0.11 10.5 3.1 0.15 10.0 3.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 EGE07694.1 - 0.25 11.3 12.7 0.53 10.2 12.7 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus FSA_C PF10479.9 EGE07694.1 - 0.65 8.1 4.6 0.92 7.6 4.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGE07694.1 - 0.69 9.9 23.2 1.5 8.8 23.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGE07694.1 - 1.7 8.6 19.4 3.4 7.6 19.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mitochondr_Som1 PF11093.8 EGE07695.1 - 4.7e-10 39.3 0.0 5.4e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Rad51 PF08423.11 EGE07697.1 - 0.0029 16.9 0.0 0.011 15.0 0.0 1.8 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 EGE07697.1 - 0.013 15.1 0.1 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PALP PF00291.25 EGE07698.1 - 1.3e-64 218.5 0.2 1.7e-64 218.1 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGE07698.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Imm2 PF14426.6 EGE07699.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm2 IlvN PF07991.12 EGE07701.1 - 3.5e-46 156.8 0.0 5.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EGE07701.1 - 1.2e-29 103.5 0.0 2.5e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EGE07701.1 - 0.0079 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGE07701.1 - 0.11 13.1 0.2 0.33 11.6 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2OG-FeII_Oxy_2 PF13532.6 EGE07702.1 - 1.9e-26 93.5 0.1 3.4e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EGE07702.1 - 2e-21 77.0 0.0 9.4e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family GST_N PF02798.20 EGE07702.1 - 0.016 15.6 0.0 0.062 13.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE07702.1 - 0.024 15.0 0.0 0.09 13.2 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE07702.1 - 0.034 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EGE07702.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GST_N_2 PF13409.6 EGE07702.1 - 0.14 12.4 0.0 0.58 10.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ECH_1 PF00378.20 EGE07703.1 - 7.4e-43 146.7 0.0 1.2e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGE07703.1 - 3.2e-30 105.8 0.0 1.6e-29 103.4 0.0 1.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Tfb5 PF06331.12 EGE07704.1 - 1.6e-18 66.4 0.0 2.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Trypsin_2 PF13365.6 EGE07705.1 - 5.2e-05 24.2 0.2 0.00018 22.4 0.2 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGE07705.1 - 5.9e-05 21.8 0.4 0.0092 14.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S29 PF02907.15 EGE07705.1 - 0.0046 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease FAD_binding_4 PF01565.23 EGE07706.1 - 2.2e-24 85.8 4.9 3.3e-24 85.2 4.9 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGE07706.1 - 9e-09 35.3 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF3328 PF11807.8 EGE07708.1 - 1.2e-21 77.5 4.3 2.8e-20 73.1 4.3 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_11 PF08241.12 EGE07709.1 - 0.0043 17.7 0.0 0.0073 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07709.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07709.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain pKID PF02173.17 EGE07709.1 - 0.29 10.6 0.8 0.67 9.5 0.8 1.5 1 0 0 1 1 1 0 pKID domain p450 PF00067.22 EGE07710.1 - 2.7e-31 108.8 0.0 4.1e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GTP_EFTU PF00009.27 EGE07711.1 - 2.3e-51 174.1 0.0 3.6e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGE07711.1 - 8e-44 148.2 3.3 1.3e-43 147.5 3.3 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGE07711.1 - 1.2e-20 73.3 0.0 2.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 EGE07711.1 - 8.1e-06 25.5 0.0 5.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EGE07711.1 - 4e-05 23.7 0.0 0.00012 22.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGE07711.1 - 0.00041 20.7 0.8 0.00079 19.8 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGE07711.1 - 0.00055 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EGE07711.1 - 0.0046 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EGE07711.1 - 0.0064 15.9 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EGE07711.1 - 0.061 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 EGE07711.1 - 0.092 12.9 1.3 0.25 11.6 1.3 1.7 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.18 EGE07712.1 - 5e-34 117.8 0.0 5.8e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EGE07712.1 - 0.0027 17.7 0.3 0.012 15.6 0.3 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF2660 PF10859.8 EGE07712.1 - 0.032 14.7 0.1 0.099 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 EGE07712.1 - 0.066 13.1 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial HORMA domain 2 zf_CCCH_4 PF18345.1 EGE07713.1 - 9.3e-07 28.7 3.7 1.6e-06 28.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGE07713.1 - 5.9e-05 22.8 1.9 9.6e-05 22.1 1.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGE07713.1 - 0.00038 20.3 0.5 0.00061 19.6 0.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGE07713.1 - 0.0012 19.2 1.8 0.0022 18.4 1.8 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGE07713.1 - 0.096 12.9 0.1 0.096 12.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger containing family Sec1 PF00995.23 EGE07714.1 - 1.2e-127 427.6 0.0 1.4e-127 427.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FHA PF00498.26 EGE07717.1 - 4e-11 43.1 0.8 6.1e-11 42.5 0.3 1.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGE07717.1 - 0.003 17.8 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TPR_1 PF00515.28 EGE07718.1 - 1.6e-41 138.4 34.6 4.9e-06 26.1 0.1 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 EGE07718.1 - 1.9e-39 130.6 34.0 7.9e-05 22.5 0.1 11.6 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGE07718.1 - 3.9e-24 82.8 25.8 0.00031 20.7 0.0 10.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGE07718.1 - 3.6e-21 75.5 22.0 3.7e-06 27.5 0.1 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGE07718.1 - 2.7e-20 71.8 29.9 9e-07 28.5 0.1 9.2 7 2 3 10 10 10 5 TPR repeat TPR_17 PF13431.6 EGE07718.1 - 7.7e-18 63.5 17.9 0.012 16.0 0.0 9.1 8 2 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGE07718.1 - 1.4e-16 60.5 36.0 0.00021 21.5 2.5 8.6 3 2 7 10 10 10 9 Tetratricopeptide repeat TPR_9 PF13371.6 EGE07718.1 - 6.1e-14 51.9 16.0 7.6e-06 26.0 0.2 6.5 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGE07718.1 - 8.4e-14 51.8 30.9 5.5e-06 26.8 2.4 8.0 6 2 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGE07718.1 - 1.8e-12 46.4 24.9 0.0097 15.9 0.6 9.7 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGE07718.1 - 6e-11 42.2 25.5 0.038 14.8 1.1 10.1 3 3 9 12 12 11 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGE07718.1 - 3e-07 30.1 27.7 0.052 13.4 1.0 9.6 11 0 0 11 11 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE07718.1 - 5.9e-07 29.6 19.4 0.087 13.1 0.4 5.9 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGE07718.1 - 2.6e-06 27.1 9.4 9.4e-05 21.9 4.7 4.0 2 1 2 4 4 4 2 MalT-like TPR region SHNi-TPR PF10516.9 EGE07718.1 - 2.1e-05 23.8 12.2 0.18 11.3 0.0 7.7 8 0 0 8 8 8 1 SHNi-TPR MAS20 PF02064.15 EGE07718.1 - 0.0026 17.9 7.6 0.013 15.6 0.6 4.0 4 1 1 5 5 5 1 MAS20 protein import receptor TAF1_subA PF14929.6 EGE07718.1 - 0.0034 16.8 0.8 0.0086 15.5 0.4 1.8 2 1 0 2 2 2 1 TAF RNA Polymerase I subunit A DUF3856 PF12968.7 EGE07718.1 - 0.0085 16.2 5.0 7.2 6.7 0.0 4.9 4 3 0 4 4 4 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 EGE07718.1 - 0.019 15.6 5.8 0.92 10.3 0.1 4.2 4 0 0 4 4 2 0 Sel1 repeat MIT PF04212.18 EGE07718.1 - 0.024 14.7 13.8 9 6.4 0.3 6.7 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 EGE07718.1 - 0.045 13.7 0.7 16 5.3 0.0 3.5 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Transglut_prok PF09017.10 EGE07718.1 - 0.047 13.0 1.4 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 Microbial transglutaminase FAT PF02259.23 EGE07718.1 - 0.13 11.5 3.4 8.5 5.5 0.3 3.1 3 0 0 3 3 3 0 FAT domain TPR_6 PF13174.6 EGE07718.1 - 0.17 12.6 28.6 9.6 7.1 0.9 9.3 11 0 0 11 11 9 0 Tetratricopeptide repeat HemY_N PF07219.13 EGE07718.1 - 0.22 11.8 10.1 42 4.4 2.0 4.6 4 1 0 4 4 3 0 HemY protein N-terminus TPR_4 PF07721.14 EGE07718.1 - 0.23 12.2 6.9 1.7e+02 3.3 0.2 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGE07718.1 - 0.6 10.6 3.8 26 5.2 0.1 3.9 3 2 0 3 3 3 0 Alkyl sulfatase dimerisation CMS1 PF14617.6 EGE07718.1 - 1.7 7.9 5.6 3.2 7.0 5.6 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit BCIP PF13862.6 EGE07718.1 - 5.1 6.8 5.8 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 p21-C-terminal region-binding protein NARP1 PF12569.8 EGE07718.1 - 8.1 5.2 29.3 0.077 11.9 0.4 4.6 2 2 2 4 4 4 0 NMDA receptor-regulated protein 1 Aminotran_4 PF01063.19 EGE07719.1 - 5.7e-26 91.8 0.0 7.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Nramp PF01566.18 EGE07720.1 - 1.5e-86 290.6 23.3 1.5e-86 290.6 23.3 2.7 3 1 0 3 3 3 1 Natural resistance-associated macrophage protein Peptidase_S8 PF00082.22 EGE07721.1 - 1.2e-28 100.2 15.6 3e-28 98.9 15.6 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE07721.1 - 1.3e-14 54.6 0.3 2e-14 54.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.8 EGE07721.1 - 0.0076 15.9 0.0 0.026 14.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3553) Sugar_tr PF00083.24 EGE07723.1 - 1e-84 285.0 21.8 1.2e-84 284.8 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE07723.1 - 3.3e-14 52.6 34.3 7.6e-14 51.4 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 EGE07725.1 - 9.8e-75 251.5 2.3 9.8e-75 251.5 2.3 3.2 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGE07725.1 - 2.5e-59 199.5 2.0 3.2e-59 199.1 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding GARS_N PF02844.15 EGE07725.1 - 0.079 13.8 0.0 8 7.3 0.0 2.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain AAA_16 PF13191.6 EGE07725.1 - 0.11 12.9 0.0 0.11 12.9 0.0 3.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 EGE07725.1 - 0.21 11.3 2.2 0.55 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGE07725.1 - 6.6 7.0 9.0 0.86 9.9 0.1 3.3 3 0 0 3 3 3 0 AAA domain DUF1899 PF08953.11 EGE07726.1 - 2.3e-32 110.7 0.0 5.2e-32 109.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGE07726.1 - 5.2e-20 71.1 0.2 1.1e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGE07726.1 - 8.1e-17 61.3 4.4 0.00045 21.0 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE07726.1 - 5.2e-07 29.9 0.0 0.0022 18.3 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGE07726.1 - 0.015 15.2 0.0 0.88 9.4 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGE07726.1 - 0.022 13.4 0.2 0.05 12.2 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 SlyX PF04102.12 EGE07726.1 - 0.037 14.6 0.2 0.078 13.6 0.2 1.6 1 0 0 1 1 1 0 SlyX SIN1 PF05422.12 EGE07726.1 - 4.8 7.7 5.5 14 6.2 0.7 2.3 1 1 1 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) zf-C3HC4_3 PF13920.6 EGE07727.1 - 0.0031 17.3 10.3 0.0055 16.5 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Transposase_21 PF02992.14 EGE07727.1 - 0.097 11.9 0.3 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Transposase family tnp2 CBFD_NFYB_HMF PF00808.23 EGE07728.1 - 4.1e-14 52.6 1.0 6.5e-14 52.0 1.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGE07728.1 - 7.2e-05 23.1 5.5 7.2e-05 23.1 5.5 2.7 2 1 2 4 4 4 1 Core histone H2A/H2B/H3/H4 Dapper PF15268.6 EGE07728.1 - 0.0077 15.2 15.3 0.0084 15.0 15.3 1.1 1 0 0 1 1 1 1 Dapper PAT1 PF09770.9 EGE07728.1 - 1 7.5 32.4 1.2 7.3 32.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTB PF00651.31 EGE07729.1 - 0.0038 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain SWIRM-assoc_2 PF16496.5 EGE07729.1 - 2.3 7.0 3.5 3.2 6.5 3.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RAI16-like PF10257.9 EGE07731.1 - 1.1e-78 264.7 0.0 1.7e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Lipase_3 PF01764.25 EGE07732.1 - 2.5e-19 69.5 0.0 5.7e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) ILVD_EDD PF00920.21 EGE07733.1 - 1.8e-209 696.6 0.3 2.2e-209 696.4 0.3 1.1 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 EGE07733.1 - 0.11 12.8 0.1 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain UPF0547 PF10571.9 EGE07735.1 - 0.19 11.8 0.5 0.44 10.7 0.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Pkinase PF00069.25 EGE07736.1 - 1.8e-45 155.4 0.0 2.8e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07736.1 - 1.9e-29 102.8 0.0 2.8e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE07736.1 - 0.00046 19.1 0.1 0.0012 17.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGE07736.1 - 0.022 14.1 0.1 0.11 11.8 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EGE07736.1 - 0.055 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.19 EGE07738.1 - 7.7e-28 97.1 3.4 1e-27 96.7 3.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 EGE07739.1 - 1.8e-60 204.6 1.2 3.2e-60 203.7 1.2 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EGE07739.1 - 0.11 12.8 0.7 9.8 6.7 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DUF4381 PF14316.6 EGE07741.1 - 0.038 14.2 4.5 0.057 13.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SARAF PF06682.12 EGE07741.1 - 0.042 13.5 5.6 0.063 12.9 5.6 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CopD PF05425.13 EGE07741.1 - 0.42 11.0 0.0 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 Copper resistance protein D Ctr PF04145.15 EGE07741.1 - 2 9.0 5.8 12 6.5 5.8 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DUF4554 PF15091.6 EGE07741.1 - 2.5 6.9 9.4 0.93 8.3 6.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4554) PX PF00787.24 EGE07742.1 - 7.9e-19 67.7 0.0 3.2e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EGE07742.1 - 6e-08 32.5 6.6 0.00075 19.1 1.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EGE07742.1 - 0.34 10.5 3.3 4.4 6.9 0.7 2.3 2 0 0 2 2 2 0 BAR domain UCH PF00443.29 EGE07743.1 - 1.2e-69 234.7 1.2 1.7e-69 234.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGE07743.1 - 5e-13 49.5 0.0 1.3e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EGE07743.1 - 1e-11 45.0 0.8 6.5e-05 22.7 0.0 3.8 3 1 1 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EGE07743.1 - 0.0018 18.0 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal ABC2_membrane_3 PF12698.7 EGE07744.1 - 0.023 13.8 0.6 0.036 13.2 0.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SPX PF03105.19 EGE07744.1 - 0.13 12.1 2.4 0.17 11.8 2.4 1.1 1 0 0 1 1 1 0 SPX domain Shisa PF13908.6 EGE07744.1 - 0.75 10.0 5.1 0.13 12.5 0.8 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EGE07744.1 - 3.6 7.9 4.6 20 5.5 3.9 2.3 2 1 0 2 2 2 0 Orf78 (ac78) ParcG PF10274.9 EGE07745.1 - 0.045 13.9 0.4 0.31 11.1 0.0 1.9 1 1 1 2 2 2 0 Parkin co-regulated protein Mu-like_Pro PF10123.9 EGE07745.1 - 0.092 12.3 9.0 0.12 12.0 9.0 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein Trigger_C PF05698.14 EGE07745.1 - 0.14 12.1 4.4 0.3 11.1 1.6 2.3 2 1 1 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus TPR_1 PF00515.28 EGE07746.1 - 2.8e-05 23.7 0.3 0.0072 16.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE07746.1 - 0.00043 20.1 4.1 0.14 12.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE07746.1 - 0.0014 18.6 6.7 0.0098 15.9 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE07746.1 - 0.029 14.6 3.6 7.9 6.8 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE07746.1 - 0.2 12.2 6.6 6.6 7.3 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGE07746.1 - 0.4 10.9 7.9 1.2 9.3 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE07746.1 - 7.1 7.7 15.1 16 6.7 0.4 4.7 3 2 1 4 4 4 0 Tetratricopeptide repeat Oxidored_q6 PF01058.22 EGE07747.1 - 2.8e-07 30.4 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit zf-C2H2 PF00096.26 EGE07748.1 - 2.9e-10 40.0 11.4 1e-05 25.7 4.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGE07748.1 - 1.4e-07 31.6 23.8 1.7e-05 25.0 0.4 3.8 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EGE07748.1 - 1.7e-07 31.5 10.3 0.00042 20.9 2.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EGE07748.1 - 4.7e-06 26.8 4.4 1.3e-05 25.4 1.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EGE07748.1 - 3.6e-05 23.6 8.7 9.5e-05 22.3 2.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGE07748.1 - 8.6e-05 22.7 6.5 0.00048 20.3 2.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EGE07748.1 - 0.013 15.4 4.4 2.2 8.3 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TFIIA PF03153.13 EGE07748.1 - 0.027 14.5 18.8 0.031 14.3 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGE07748.1 - 0.047 13.3 10.6 0.065 12.8 10.6 1.3 1 0 0 1 1 1 0 Spt20 family Actin_micro PF17003.5 EGE07748.1 - 0.18 11.0 0.4 0.27 10.3 0.4 1.2 1 0 0 1 1 1 0 Putative actin-like family Roughex PF06020.11 EGE07748.1 - 0.42 9.7 4.1 0.67 9.0 4.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein zf-C2H2_11 PF16622.5 EGE07748.1 - 0.45 10.3 7.3 5.3 6.9 0.8 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EGE07748.1 - 0.52 10.4 4.5 0.28 11.2 0.6 2.1 2 0 0 2 2 2 0 BED zinc finger Presenilin PF01080.17 EGE07748.1 - 1.8 7.2 2.8 2.3 6.9 2.8 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 EGE07748.1 - 1.9 6.7 13.4 2.3 6.4 13.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nrap_D5 PF17406.2 EGE07749.1 - 0.67 9.7 2.1 8.2 6.2 0.2 2.3 2 1 0 2 2 2 0 Nrap protein PAP/OAS1-like domain 5 V-SNARE_C PF12352.8 EGE07749.1 - 1.5 9.2 7.3 0.092 13.0 0.8 2.3 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.23 EGE07750.1 - 2.4e-120 403.5 0.0 2.7e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Transposase_22 PF02994.14 EGE07750.1 - 0.015 15.5 0.3 0.18 12.0 0.0 2.6 3 0 0 3 3 3 0 L1 transposable element RBD-like domain SF3b1 PF08920.10 EGE07751.1 - 1.1e-15 58.2 9.9 8.5e-14 52.1 9.5 3.1 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EGE07751.1 - 2.1e-11 44.1 8.3 0.19 12.1 0.1 8.1 5 3 4 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 EGE07751.1 - 4.1e-11 43.1 2.6 0.0099 16.4 0.0 6.8 7 1 1 8 8 7 2 HEAT-like repeat HEAT PF02985.22 EGE07751.1 - 2.8e-09 36.4 7.9 0.64 10.4 0.2 9.1 10 0 0 10 10 8 2 HEAT repeat Cnd1 PF12717.7 EGE07751.1 - 1.4e-05 25.2 1.4 4.6 7.3 0.0 6.1 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGE07751.1 - 2.9e-05 24.6 0.2 2.1 9.0 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGE07751.1 - 0.00011 22.2 0.5 0.055 13.4 0.0 4.8 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 EGE07751.1 - 0.00015 21.5 0.3 1.1 8.9 0.0 4.1 5 1 0 5 5 5 2 NUC173 domain UNC45-central PF11701.8 EGE07751.1 - 0.00083 19.4 0.0 0.0032 17.4 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central UME PF08064.13 EGE07751.1 - 0.0032 17.4 0.5 7.6 6.5 0.0 4.9 7 0 0 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 EGE07751.1 - 0.004 16.8 0.1 0.86 9.1 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal TAF6_C PF07571.13 EGE07751.1 - 0.02 15.2 0.0 0.97 9.8 0.0 3.4 3 1 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 EGE07751.1 - 0.064 11.5 0.2 6.1 5.0 0.0 3.7 2 1 1 3 3 3 0 Down-regulated in metastasis CRM1_C PF08767.11 EGE07751.1 - 0.14 11.3 0.0 0.56 9.3 0.0 2.0 1 0 0 1 1 1 0 CRM1 C terminal Ecm29 PF13001.7 EGE07751.1 - 0.15 10.7 0.0 1.5 7.4 0.0 2.3 2 1 1 3 3 3 0 Proteasome stabiliser DUF3455 PF11937.8 EGE07752.1 - 9.7e-35 120.3 0.0 1.2e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_11 PF08241.12 EGE07753.1 - 6.1e-05 23.6 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07753.1 - 0.0053 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGE07753.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family SAP PF02037.27 EGE07755.1 - 3.7e-12 45.7 0.6 6.5e-12 44.9 0.1 1.7 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 EGE07755.1 - 1.2e-06 28.2 0.1 1.2e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain CCT_2 PF09425.10 EGE07755.1 - 0.1 12.5 6.5 0.84 9.6 1.3 2.8 2 0 0 2 2 2 0 Divergent CCT motif FXMRP1_C_core PF12235.8 EGE07755.1 - 2.3 8.9 15.4 0.45 11.2 6.8 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal SSrecog PF03531.14 EGE07756.1 - 4e-30 103.5 0.4 5e-29 100.0 0.0 3.0 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EGE07756.1 - 4.9e-30 103.8 0.3 8.9e-29 99.8 0.1 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EGE07756.1 - 1.6e-25 89.4 0.1 6.6e-25 87.4 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rax2 PF12768.7 EGE07757.1 - 2.2e-55 187.5 0.4 4.4e-43 147.2 0.1 3.3 2 1 1 3 3 3 2 Cortical protein marker for cell polarity Reg_prop PF07494.11 EGE07757.1 - 0.31 11.4 4.0 19 5.9 0.0 5.4 6 0 0 6 6 6 0 Two component regulator propeller Fungal_trans_2 PF11951.8 EGE07758.1 - 1.1e-08 34.3 0.4 2e-08 33.5 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE07758.1 - 2.6e-08 33.8 11.7 4.8e-08 33.0 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EGE07759.1 - 9.6e-10 38.8 0.0 2.1e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FMO-like PF00743.19 EGE07760.1 - 6.3e-12 44.7 1.4 8.1e-11 41.0 0.6 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE07760.1 - 7.7e-11 41.8 1.2 1.7e-06 27.6 0.8 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE07760.1 - 1.7e-10 40.6 0.0 9.6e-06 25.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07760.1 - 7.2e-09 35.2 0.8 3.6e-05 23.1 0.0 3.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGE07760.1 - 1.3e-08 34.9 0.0 0.0081 15.8 0.0 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE07760.1 - 3.4e-08 33.6 0.2 1.1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGE07760.1 - 7.9e-05 22.0 0.0 0.003 16.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 EGE07760.1 - 0.00018 21.5 0.0 0.51 10.3 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 EGE07760.1 - 0.0032 16.6 0.2 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Mqo PF06039.15 EGE07760.1 - 0.034 12.7 0.0 2.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 EGE07760.1 - 0.048 12.4 0.2 8.1 5.0 0.1 3.0 3 0 0 3 3 3 0 HI0933-like protein OGG_N PF07934.12 EGE07761.1 - 4.5e-36 123.6 0.1 7.8e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGE07761.1 - 1.3e-15 57.7 0.0 2.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGE07761.1 - 0.00044 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 EGE07762.1 - 7.9e-31 105.7 0.1 2.9e-13 49.4 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE07762.1 - 1e-06 28.5 0.0 0.095 12.6 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif 7tm_2 PF00002.24 EGE07764.1 - 0.00064 19.1 12.3 0.0013 18.1 11.3 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Chromate_transp PF02417.15 EGE07767.1 - 6.1e-58 195.4 34.7 2e-31 109.3 14.0 2.4 3 0 0 3 3 3 2 Chromate transporter NDUF_B12 PF08122.12 EGE07767.1 - 0.1 12.6 1.4 52 4.0 0.1 4.7 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase B12 subunit family Ribosomal_S13_N PF08069.12 EGE07768.1 - 9.1e-30 102.5 0.2 1.5e-29 101.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGE07768.1 - 2.3e-15 56.6 0.2 3.3e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EGE07768.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.11 EGE07769.1 - 2e-24 85.7 0.0 6e-24 84.2 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 EGE07770.1 - 2.3e-14 52.8 0.0 3.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif RRM_1 PF00076.22 EGE07771.1 - 3.1e-19 68.6 0.0 4.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE07771.1 - 0.00067 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.9 EGE07772.1 - 2.4e-32 112.5 0.7 4.8e-31 108.3 0.0 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 EGE07772.1 - 8e-32 109.7 3.3 8e-32 109.7 3.3 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGE07772.1 - 6.5e-28 96.8 1.1 6.5e-28 96.8 1.1 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EGE07772.1 - 5.4e-14 51.5 2.9 5.4e-14 51.5 2.9 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EGE07772.1 - 1.1e-08 34.8 9.8 1.1e-08 34.8 9.8 2.7 2 0 0 2 2 2 1 PHD-finger Bromodomain PF00439.25 EGE07772.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-PHD-like PF15446.6 EGE07772.1 - 7.8 6.1 13.6 0.016 14.8 2.1 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Myb_DNA-bind_6 PF13921.6 EGE07775.1 - 7.2e-09 35.8 1.4 6.5e-08 32.7 0.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGE07775.1 - 2.7e-06 27.5 0.2 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_M22 PF00814.25 EGE07776.1 - 1.6e-45 156.0 0.0 7.5e-41 140.6 0.0 3.4 2 1 0 2 2 2 2 Glycoprotease family Glyco_transf_25 PF01755.17 EGE07779.1 - 6.7e-06 26.1 0.0 2.7e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Pyr_redox_2 PF07992.14 EGE07781.1 - 3.2e-12 46.3 0.0 6.8e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGE07781.1 - 4.3e-12 45.2 0.1 9.4e-11 40.8 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EGE07781.1 - 1.6e-11 44.3 0.1 3.6e-07 30.3 0.0 3.0 2 1 1 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGE07781.1 - 2e-08 33.9 0.0 3.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07781.1 - 8.1e-06 25.2 0.0 4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGE07781.1 - 0.00041 20.4 0.1 3.7 7.5 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGE07781.1 - 0.0013 19.3 0.1 0.85 10.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE07781.1 - 0.0048 16.5 0.2 0.09 12.3 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGE07781.1 - 0.018 15.1 0.0 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EGE07781.1 - 0.022 13.9 0.0 0.36 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EGE07781.1 - 0.077 12.0 0.0 21 4.0 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 EGE07781.1 - 0.088 12.0 0.2 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FeoC PF09012.10 EGE07782.1 - 0.071 13.2 0.2 1 9.5 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator Mito_carr PF00153.27 EGE07783.1 - 1.6e-73 242.7 0.3 4.3e-25 87.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGE07783.1 - 2.1e-13 50.5 6.8 5.1e-09 36.5 0.7 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGE07783.1 - 5.7e-12 44.5 6.3 6.9e-07 28.7 0.1 5.6 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 EGE07783.1 - 1.4e-10 39.9 11.0 8.4e-07 28.1 0.1 5.6 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 EGE07783.1 - 3.4e-07 30.0 1.0 0.47 10.3 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.6 EGE07783.1 - 2.6e-06 26.6 2.5 5.7e-05 22.4 0.1 3.4 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 EGE07783.1 - 0.091 13.1 0.0 23 5.4 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain Metallophos PF00149.28 EGE07784.1 - 1.2e-12 48.8 0.1 2e-12 48.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE07784.1 - 1.3e-06 28.7 0.1 2.1e-05 24.8 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EGE07784.1 - 0.069 12.5 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily NUDIX PF00293.28 EGE07785.1 - 0.00036 20.6 0.0 0.00065 19.7 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain DUF726 PF05277.12 EGE07786.1 - 2e-127 424.8 2.9 2e-127 424.8 2.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) RTC4 PF14474.6 EGE07787.1 - 8.2e-33 113.1 0.0 1.7e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Tmemb_14 PF03647.13 EGE07788.1 - 8.2e-21 74.5 7.6 1.3e-20 73.9 7.6 1.3 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 EGE07789.1 - 1.1e-45 154.4 0.2 1.5e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 DAD family HA2 PF04408.23 EGE07790.1 - 1.7e-20 73.3 0.0 1.7e-20 73.3 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGE07790.1 - 4.9e-17 62.1 0.0 1.8e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGE07790.1 - 7.4e-15 55.3 0.0 2.1e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGE07790.1 - 4.2e-06 26.6 0.2 9.8e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGE07790.1 - 0.00013 22.3 0.1 0.00039 20.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGE07790.1 - 0.00022 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGE07790.1 - 0.0006 19.0 0.0 0.0038 16.3 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGE07790.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE07790.1 - 0.0048 17.2 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGE07790.1 - 0.0079 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 KaiC SRP54 PF00448.22 EGE07790.1 - 0.01 15.5 0.2 0.032 13.9 0.2 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EGE07790.1 - 0.015 15.3 0.1 0.076 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EGE07790.1 - 0.028 14.4 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EGE07790.1 - 0.059 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Glug PF07581.12 EGE07790.1 - 0.085 13.3 0.0 0.3 11.6 0.0 1.9 1 0 0 1 1 1 0 The GLUG motif Microtub_bd PF16796.5 EGE07790.1 - 0.098 12.6 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding NACHT PF05729.12 EGE07790.1 - 0.17 11.8 0.8 1.4 8.9 0.1 2.4 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 EGE07790.1 - 7.6 7.0 8.1 2.5 8.6 0.1 3.0 2 1 1 3 3 3 0 AAA domain DUF5427 PF10310.9 EGE07792.1 - 2.4e-168 560.9 0.0 2.9e-168 560.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EGE07792.1 - 0.014 15.6 0.2 0.041 14.1 0.2 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Pex14_N PF04695.13 EGE07792.1 - 1.1 9.9 9.2 0.99 10.1 6.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2462 PF09495.10 EGE07793.1 - 1.7e-23 83.1 12.0 1.7e-23 83.1 12.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Gly_transf_sug PF04488.15 EGE07794.1 - 9.6e-11 42.2 0.0 2.9e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GvpL_GvpF PF06386.11 EGE07794.1 - 0.028 14.3 4.1 0.23 11.3 4.2 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Caps_synth PF05704.12 EGE07794.1 - 0.033 13.6 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein AAA_23 PF13476.6 EGE07794.1 - 0.041 14.4 4.2 0.067 13.7 4.2 1.3 1 0 0 1 1 1 0 AAA domain EMC3_TMCO1 PF01956.16 EGE07794.1 - 0.1 12.4 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RR_TM4-6 PF06459.12 EGE07794.1 - 0.18 11.6 6.1 0.32 10.8 6.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 EGE07794.1 - 0.3 11.4 9.9 0.6 10.4 9.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TcdA_TcdB PF12919.7 EGE07794.1 - 0.6 9.3 6.7 0.69 9.1 0.0 2.8 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Connexin PF00029.19 EGE07794.1 - 0.93 9.2 2.8 1.5 8.5 2.8 1.2 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 EGE07794.1 - 1.3 7.8 7.0 2.4 6.9 7.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMPIT PF07851.13 EGE07794.1 - 5.3 6.2 4.4 9 5.4 4.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EGE07794.1 - 8.6 5.6 10.3 0.34 10.2 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 EGE07795.1 - 0.002 18.6 4.9 0.0048 17.4 4.9 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF501 PF04417.12 EGE07795.1 - 8.2 6.2 6.1 3.5 7.4 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) CYSTM PF12734.7 EGE07796.1 - 3.4 8.1 21.5 1.8e+04 -4.1 21.5 2.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Glyco_transf_90 PF05686.12 EGE07797.1 - 1e-36 126.7 4.7 2.9e-36 125.2 4.7 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGE07797.1 - 0.033 14.6 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyoxalase PF00903.25 EGE07799.1 - 8.3e-25 87.5 0.9 1.3e-17 64.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGE07799.1 - 1.3e-14 54.3 0.2 5.9e-07 29.7 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGE07799.1 - 1.2e-07 32.1 0.1 0.00073 19.7 0.2 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EGE07799.1 - 0.00087 19.5 0.2 0.013 15.7 0.2 2.3 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 EGE07799.1 - 0.029 14.9 0.0 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) TPR_17 PF13431.6 EGE07800.1 - 0.00069 19.8 0.0 0.054 13.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat HgmA PF04209.13 EGE07801.1 - 6.2e-174 578.7 0.0 7.6e-174 578.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 EGE07802.1 - 2e-55 187.8 0.0 2.8e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GST_N PF02798.20 EGE07803.1 - 2.5e-10 40.6 0.0 5.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE07803.1 - 6.2e-10 39.3 0.0 1.4e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE07803.1 - 5.2e-09 36.4 0.0 8.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE07803.1 - 1.3e-08 34.9 0.0 3.8e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGE07803.1 - 1.7e-06 28.1 0.2 4.9e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE07803.1 - 0.00037 20.5 0.2 0.00077 19.4 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TYW3 PF02676.14 EGE07803.1 - 0.073 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 Oxidored_FMN PF00724.20 EGE07804.1 - 1.8e-56 191.9 0.0 2.3e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family BATS PF06968.13 EGE07805.1 - 5.4e-22 77.7 0.1 2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EGE07805.1 - 6.5e-15 55.9 0.0 1.5e-14 54.7 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_3 PF00202.21 EGE07806.1 - 1e-40 139.6 0.0 1.7e-19 69.8 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EGE07806.1 - 5.5e-19 68.8 0.0 9.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 EGE07807.1 - 8e-40 137.1 0.0 9.9e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGE07807.1 - 0.052 12.5 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGE07807.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GTP_EFTU PF00009.27 EGE07808.1 - 2.5e-30 105.5 0.1 8e-30 103.8 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGE07808.1 - 5.2e-30 104.0 0.1 1.1e-29 103.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGE07808.1 - 8.5e-10 38.9 0.4 1.9e-09 37.8 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGE07808.1 - 0.16 12.1 0.0 0.49 10.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase CTP_transf_like PF01467.26 EGE07809.1 - 9.6e-25 87.5 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Ran-binding PF05508.11 EGE07810.1 - 2.8e-111 371.4 0.0 7.9e-98 327.3 0.0 2.1 1 1 1 2 2 2 2 RanGTP-binding protein USP7_ICP0_bdg PF12436.8 EGE07811.1 - 3.6e-41 141.1 0.0 6.1e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EGE07811.1 - 1.1e-33 116.8 0.3 1.6e-33 116.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07811.1 - 2.9e-08 33.7 0.1 5e-07 29.6 0.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BSD PF03909.17 EGE07812.1 - 1.5e-19 69.7 0.6 3.3e-19 68.6 0.6 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EGE07812.1 - 0.0095 15.9 2.6 0.014 15.4 2.6 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EGE07812.1 - 5.1 7.5 5.0 1.9 8.8 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rad4 PF03835.15 EGE07814.1 - 5.5e-37 126.7 0.0 1.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EGE07814.1 - 7.1e-28 96.8 0.0 1.5e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EGE07814.1 - 1.3e-19 69.7 0.1 3.2e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGE07814.1 - 4.1e-16 59.7 0.8 4.1e-16 59.7 0.8 2.8 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 CENP-F_leu_zip PF10473.9 EGE07815.1 - 0.00065 19.7 23.5 0.00065 19.7 23.5 9.3 2 1 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 EGE07815.1 - 0.0013 18.6 25.4 0.0013 18.6 25.4 6.3 2 1 3 5 5 5 1 Ezrin/radixin/moesin family Filament PF00038.21 EGE07815.1 - 0.0024 17.5 158.5 0.099 12.2 33.7 5.5 1 1 4 5 5 5 3 Intermediate filament protein DUF4200 PF13863.6 EGE07815.1 - 0.0056 17.1 16.9 0.0056 17.1 16.9 10.2 2 1 9 11 11 11 3 Domain of unknown function (DUF4200) Pox_A_type_inc PF04508.12 EGE07815.1 - 0.26 11.2 22.2 0.53 10.2 0.1 8.6 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat DUF3287 PF11690.8 EGE07815.1 - 1.9 8.2 7.0 0.66 9.7 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) PTPA PF03095.15 EGE07817.1 - 3.1e-118 394.6 0.0 3.6e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 EGE07818.1 - 1e-69 235.7 1.3 1.2e-69 235.5 1.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Glyco_hydro_3_C PF01915.22 EGE07819.1 - 1.3e-48 165.7 0.0 2.3e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EGE07819.1 - 3.3e-30 105.5 0.0 7.7e-26 91.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EGE07819.1 - 1.6e-18 66.6 0.2 2.9e-18 65.7 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.20 EGE07820.1 - 1.1e-38 132.8 0.0 1.3e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily BUD22 PF09073.10 EGE07821.1 - 2.4e-101 340.2 23.3 3.3e-101 339.8 23.3 1.2 1 0 0 1 1 1 1 BUD22 SIS PF01380.22 EGE07822.1 - 3.8e-06 26.8 0.1 1.4e-05 25.0 0.1 1.9 1 1 0 1 1 1 1 SIS domain Ubie_methyltran PF01209.18 EGE07823.1 - 1.4e-78 263.5 0.0 2.1e-78 262.8 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGE07823.1 - 3.6e-16 59.6 0.0 6.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07823.1 - 6.6e-15 55.5 0.0 1.4e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07823.1 - 8.7e-13 48.3 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07823.1 - 1e-10 42.2 0.0 1.8e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE07823.1 - 4.5e-06 26.6 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGE07823.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Skp1 PF01466.19 EGE07824.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, dimerisation domain E1_dh PF00676.20 EGE07825.1 - 8.2e-91 304.1 0.2 1e-90 303.8 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGE07825.1 - 0.00058 19.7 0.1 0.0021 17.9 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGE07825.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.10 EGE07825.1 - 0.055 12.3 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 XFP N-terminal domain DUF533 PF04391.12 EGE07826.1 - 0.029 13.9 0.1 0.029 13.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF533) zf-RING_4 PF14570.6 EGE07827.1 - 2.1e-10 40.2 7.6 9.2e-10 38.2 7.6 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EGE07827.1 - 6e-05 22.8 0.0 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rubredoxin_2 PF18073.1 EGE07827.1 - 0.011 15.5 2.6 0.021 14.6 2.6 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain ALP_N PF17989.1 EGE07827.1 - 0.027 14.7 0.0 0.079 13.1 0.0 1.8 2 0 0 2 2 2 0 Actin like proteins N terminal domain zf-C3HC4_3 PF13920.6 EGE07827.1 - 0.58 10.1 4.7 1.7 8.6 4.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 EGE07828.1 - 7.8e-46 155.7 0.0 1.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Myb_DNA-binding PF00249.31 EGE07829.1 - 3.6e-33 113.5 10.4 3.6e-12 46.3 0.5 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE07829.1 - 1e-26 92.9 9.8 1.5e-14 54.0 0.3 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGE07829.1 - 0.00013 21.8 0.6 0.023 14.6 0.0 3.1 3 0 0 3 3 3 1 Myb DNA-binding like Atg29_N PF18388.1 EGE07829.1 - 0.0047 16.7 8.5 0.066 13.0 1.1 2.7 3 0 0 3 3 3 2 Atg29 N-terminal domain Myb_DNA-bind_4 PF13837.6 EGE07829.1 - 0.039 14.3 10.1 1.3 9.5 0.7 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGE07829.1 - 0.093 12.9 1.7 0.36 11.0 0.0 2.4 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 PriCT_2 PF08707.11 EGE07829.1 - 0.68 10.3 3.4 15 6.0 2.2 3.3 2 1 1 3 3 3 0 Primase C terminal 2 (PriCT-2) Rap1_C PF11626.8 EGE07829.1 - 1.2 9.3 5.2 2.7 8.1 0.5 2.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AA_permease_2 PF13520.6 EGE07830.1 - 3.9e-85 286.2 32.0 4.7e-85 286.0 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease SseC PF04888.12 EGE07830.1 - 0.23 11.0 1.2 0.54 9.8 0.1 1.9 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PsbN PF02468.15 EGE07830.1 - 0.85 9.5 4.0 0.71 9.8 1.3 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) p450 PF00067.22 EGE07831.1 - 2.6e-68 230.9 0.0 3.1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 EGE07832.1 - 2.9e-90 303.2 0.0 3.5e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE07832.1 - 2.1e-13 50.2 0.0 7.4e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07832.1 - 5.1e-09 35.7 0.0 5.3e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGE07832.1 - 1.6e-08 34.2 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE07832.1 - 0.02 14.9 0.1 3.4 7.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGE07832.1 - 0.036 14.6 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_3 PF07859.13 EGE07833.1 - 1.2e-61 208.2 0.1 1.7e-61 207.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE07833.1 - 3.8e-07 29.8 0.0 0.0021 17.6 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EGE07833.1 - 2.2e-05 23.5 0.2 6.7e-05 21.9 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EGE07833.1 - 0.00055 20.6 3.8 0.0015 19.1 3.7 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EGE07833.1 - 0.015 14.8 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lyase_1 PF00206.20 EGE07834.1 - 1.5e-95 320.2 0.0 1.5e-94 316.9 0.0 2.1 1 1 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGE07834.1 - 1e-20 73.9 0.0 2.2e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_1 PF00583.25 EGE07836.1 - 2.4e-10 40.6 0.0 3.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE07836.1 - 9.2e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE07836.1 - 3.9e-06 27.2 0.3 6e-06 26.6 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Thiolase_C PF02803.18 EGE07836.1 - 0.031 13.9 0.0 5.9 6.6 0.0 2.7 3 0 0 3 3 3 0 Thiolase, C-terminal domain DUF4683 PF15735.5 EGE07836.1 - 0.22 11.1 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) Ribosomal_S30 PF04758.14 EGE07837.1 - 4.8e-30 103.5 8.6 5.2e-30 103.4 8.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_L24e PF01246.20 EGE07838.1 - 4e-29 100.6 1.3 5.1e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e UQ_con PF00179.26 EGE07839.1 - 3.8e-47 159.5 0.0 4.2e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE07839.1 - 0.0022 17.7 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGE07839.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EGE07839.1 - 0.021 15.1 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 EGE07840.1 - 7e-09 36.2 15.1 0.0043 17.9 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EGE07840.1 - 3.6e-07 29.7 17.1 3.6e-07 29.7 17.1 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 EGE07840.1 - 0.0021 18.3 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EGE07840.1 - 0.045 14.1 13.8 0.13 12.6 13.8 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EGE07840.1 - 0.29 11.0 9.9 0.79 9.6 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE07840.1 - 0.45 10.4 9.1 1.2 9.1 9.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4HBT PF03061.22 EGE07841.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EGE07841.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) UCH PF00443.29 EGE07842.1 - 1.3e-48 165.8 5.7 2e-48 165.1 5.7 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGE07842.1 - 8.2e-12 45.3 10.7 2.9e-11 43.5 10.7 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGE07842.1 - 9e-11 41.4 0.0 2.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family RILP PF11461.8 EGE07842.1 - 0.63 10.3 0.0 0.63 10.3 0.0 3.2 3 1 0 3 3 3 0 Rab interacting lysosomal protein PTPRCAP PF15713.5 EGE07842.1 - 1.1 9.6 9.7 3 8.1 9.7 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2992 PF11208.8 EGE07842.1 - 3.6 7.8 14.3 6.9 6.9 14.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) ARPC4 PF05856.12 EGE07843.1 - 1.4e-53 181.0 3.3 2.9e-47 160.4 1.2 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) TYW3 PF02676.14 EGE07845.1 - 2.7e-44 151.1 0.0 4.2e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.10 EGE07846.1 - 1.1e-31 110.5 1.2 2e-31 109.6 1.2 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Sporozoite_P67 PF05642.11 EGE07846.1 - 0.21 9.6 6.7 0.28 9.2 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 3H PF02829.14 EGE07850.1 - 0.068 13.5 0.2 0.11 12.8 0.2 1.3 1 0 0 1 1 1 0 3H domain COX15-CtaA PF02628.15 EGE07851.1 - 3.6e-113 377.9 5.3 4.3e-113 377.7 5.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Prok-RING_2 PF14445.6 EGE07852.1 - 0.22 11.7 5.9 0.39 10.9 5.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RING_4 PF14570.6 EGE07852.1 - 0.51 10.2 4.2 1.1 9.1 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RanBP PF00641.18 EGE07852.1 - 0.81 9.1 9.8 0.021 14.1 3.4 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others tRNA-synt_2 PF00152.20 EGE07853.1 - 2.4e-78 263.4 0.5 3.2e-78 263.0 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGE07853.1 - 3e-12 46.4 0.0 8.3e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGE07853.1 - 1.2e-05 24.9 0.1 0.018 14.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MSP1b PF03429.13 EGE07853.1 - 1 7.4 4.6 1.4 6.9 4.6 1.2 1 0 0 1 1 1 0 Major surface protein 1B Dynamin_N PF00350.23 EGE07854.1 - 2.1e-23 83.2 0.0 7.2e-23 81.5 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EGE07854.1 - 8.3e-22 77.7 0.0 1.1e-16 60.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 EGE07854.1 - 2.5e-05 24.4 0.7 8.3e-05 22.7 0.7 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGE07854.1 - 0.0016 18.5 0.0 0.018 15.1 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGE07854.1 - 0.009 16.2 0.1 0.049 13.9 0.1 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGE07854.1 - 0.11 12.0 0.1 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 Ras family NTP_transferase PF00483.23 EGE07855.1 - 3e-31 108.9 0.0 4e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGE07855.1 - 9.5e-09 34.7 7.4 3.9e-06 26.4 0.1 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGE07855.1 - 2.3e-08 34.6 0.0 3.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EGE07855.1 - 0.0098 15.6 0.0 0.034 13.9 0.0 1.7 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EGE07855.1 - 0.073 12.8 2.0 0.51 10.1 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Bys1 PF04681.12 EGE07856.1 - 3.7e-12 46.4 0.1 4.2e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Putative_PNPOx PF01243.20 EGE07858.1 - 2.2e-09 37.4 0.0 0.00027 21.0 0.0 2.8 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EGE07858.1 - 0.00014 22.2 0.0 0.014 15.8 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain zf-RING_2 PF13639.6 EGE07859.1 - 1.5e-08 34.8 3.8 2.4e-08 34.2 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGE07859.1 - 2.7e-06 27.5 4.2 5.3e-05 23.4 4.2 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGE07859.1 - 0.00021 21.2 0.8 0.00034 20.6 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGE07859.1 - 0.00051 20.0 6.7 0.00092 19.2 6.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGE07859.1 - 0.0074 16.1 4.6 0.028 14.2 4.4 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE07859.1 - 0.024 14.5 2.5 0.3 11.0 2.3 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EGE07859.1 - 0.024 14.9 0.2 0.055 13.7 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-RING_11 PF17123.5 EGE07859.1 - 0.075 12.8 3.3 0.14 11.9 3.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 EGE07859.1 - 0.47 10.4 4.1 5.7 6.9 0.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EGE07860.1 - 1.9e-07 31.2 35.5 0.00018 21.7 10.8 4.0 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGE07860.1 - 5.1e-05 23.5 4.8 5.1e-05 23.5 4.8 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 EGE07860.1 - 8.6e-05 22.4 3.9 8.6e-05 22.4 3.9 3.7 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGE07860.1 - 0.001 18.9 4.4 0.001 18.9 4.4 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE07860.1 - 0.0015 18.4 4.8 0.0015 18.4 4.8 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE07860.1 - 0.0015 18.5 3.8 0.0015 18.5 3.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Atx10homo_assoc PF09759.9 EGE07861.1 - 2.2e-32 111.0 0.4 2.2e-32 111.0 0.4 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DHHC PF01529.20 EGE07862.1 - 6e-31 107.3 8.6 6e-31 107.3 8.6 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase Rap1_C PF11626.8 EGE07863.1 - 1.8e-20 72.8 0.1 2.3e-18 66.0 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EGE07863.1 - 9.6e-20 70.5 8.0 1.2e-19 70.2 0.6 2.9 2 1 1 3 3 3 1 Rap1 Myb domain BRCT_2 PF16589.5 EGE07863.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 EGE07863.1 - 8.7e-07 29.5 9.0 0.00037 21.0 1.2 3.5 3 1 0 3 3 3 2 Rap1, DNA-binding LIG3_BRCT PF16759.5 EGE07863.1 - 0.00056 20.1 0.2 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Chromo_shadow PF01393.19 EGE07864.1 - 6.3e-20 71.0 0.2 2.1e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EGE07864.1 - 6.5e-14 51.6 0.1 1.5e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain YL1 PF05764.13 EGE07864.1 - 1.9 8.6 11.8 2.2 8.3 11.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cpn60_TCP1 PF00118.24 EGE07865.1 - 1.5e-159 531.8 4.3 1.7e-159 531.6 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EGE07865.1 - 0.044 14.0 2.3 6.3 7.0 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF4960 PF16324.5 EGE07866.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4960) DUF3295 PF11702.8 EGE07870.1 - 1.6e-155 519.3 48.1 1.6e-155 519.3 48.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EGE07870.1 - 1e-11 44.4 2.9 3e-11 42.9 2.9 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) ParBc PF02195.18 EGE07870.1 - 0.0034 17.6 0.5 0.27 11.5 0.1 3.5 3 1 0 3 3 3 1 ParB-like nuclease domain Polysacc_deac_1 PF01522.21 EGE07873.1 - 1.3e-19 70.3 0.0 8.3e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EGE07873.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase zf-CHY PF05495.12 EGE07874.1 - 2.4e-11 43.9 7.5 2.4e-11 43.9 7.5 3.6 3 1 1 4 4 4 1 CHY zinc finger RWD PF05773.22 EGE07874.1 - 0.01 16.1 0.1 0.71 10.2 0.0 2.5 2 0 0 2 2 2 0 RWD domain Rsm1 PF08600.10 EGE07876.1 - 1.8e-24 85.7 0.0 1.8e-24 85.7 0.0 2.4 2 1 1 3 3 3 1 Rsm1-like zf-C3HC PF07967.13 EGE07876.1 - 8.9e-22 77.6 2.3 1.3e-19 70.5 0.1 3.3 2 2 1 3 3 3 2 C3HC zinc finger-like Pox_MCEL PF03291.16 EGE07877.1 - 1.7e-64 218.1 0.0 3.4e-41 141.5 0.0 3.2 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.12 EGE07877.1 - 7.6e-10 39.4 0.1 6.1e-08 33.3 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07877.1 - 1.9e-09 38.1 0.3 0.0012 19.5 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07877.1 - 2.1e-06 28.3 0.5 0.03 15.0 0.0 3.2 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07877.1 - 3.1e-05 23.8 0.0 0.074 12.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EGE07877.1 - 0.00031 20.0 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family zf-Nse PF11789.8 EGE07878.1 - 1.8e-21 75.7 1.9 3.1e-21 74.9 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGE07878.1 - 0.00015 21.7 0.1 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Pap_E4 PF02711.14 EGE07878.1 - 0.098 13.6 0.3 0.098 13.6 0.3 3.5 3 0 0 3 3 3 0 E4 protein zf-C3HC4_2 PF13923.6 EGE07878.1 - 0.26 11.2 1.6 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EGE07878.1 - 0.64 9.8 3.6 0.78 9.5 0.1 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ufd2P_core PF10408.9 EGE07878.1 - 0.68 8.5 2.9 1 7.9 2.9 1.3 1 0 0 1 1 1 0 Ubiquitin elongating factor core BSP_II PF05432.11 EGE07878.1 - 3.1 7.4 37.6 0.024 14.3 8.1 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) SNARE PF05739.19 EGE07878.1 - 4.4 7.4 8.1 11 6.1 0.1 3.1 3 0 0 3 3 3 0 SNARE domain MRP-S31 PF15433.6 EGE07878.1 - 7.7 6.1 17.2 0.1 12.3 4.1 2.4 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Mito_carr PF00153.27 EGE07879.1 - 6.7e-53 176.6 4.4 8.4e-18 64.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Tir_receptor_N PF07490.11 EGE07879.1 - 0.00036 20.5 1.2 0.00062 19.7 1.2 1.3 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus Meiotic_rec114 PF03525.14 EGE07880.1 - 5.6e-10 38.7 1.3 1.5e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 Meiotic recombination protein rec114 HS1_rep PF02218.15 EGE07880.1 - 0.06 13.7 1.3 0.13 12.6 1.3 1.4 1 0 0 1 1 1 0 Repeat in HS1/Cortactin DUF4094 PF13334.6 EGE07881.1 - 0.16 12.4 0.0 0.26 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Copper-fist PF00649.18 EGE07882.1 - 4.6e-23 80.4 1.4 1.4e-22 78.9 1.4 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain TFIIA PF03153.13 EGE07882.1 - 7.5 6.4 17.7 13 5.6 17.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 EGE07883.1 - 2.7e-10 40.2 9.6 4e-10 39.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EGE07884.1 - 6.8e-06 25.9 1.1 2.7e-05 24.0 1.1 2.0 1 1 0 1 1 1 1 F-box-like SUIM_assoc PF16619.5 EGE07884.1 - 0.0069 16.4 2.4 0.016 15.3 2.4 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Dehydrin PF00257.19 EGE07884.1 - 0.037 14.6 0.5 0.055 14.0 0.5 1.2 1 0 0 1 1 1 0 Dehydrin Androgen_recep PF02166.16 EGE07884.1 - 0.072 11.9 2.0 0.1 11.4 2.0 1.1 1 0 0 1 1 1 0 Androgen receptor DUF4571 PF15137.6 EGE07884.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) F-box PF00646.33 EGE07884.1 - 7 6.7 6.5 1.1e+02 2.8 6.5 2.4 1 1 0 1 1 1 0 F-box domain Pyr_redox_3 PF13738.6 EGE07885.1 - 4.5e-16 59.0 0.0 5.9e-15 55.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EGE07885.1 - 2.1e-13 49.5 0.0 1.6e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EGE07885.1 - 2.4e-12 46.7 0.0 2.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE07885.1 - 5.9e-11 42.1 0.0 1.3e-07 31.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGE07885.1 - 4.7e-07 29.3 0.1 2e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGE07885.1 - 0.00015 21.9 0.5 0.00086 19.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE07885.1 - 0.00059 20.3 1.4 0.27 11.8 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGE07885.1 - 0.00082 19.4 0.0 0.084 12.9 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EGE07885.1 - 0.00087 18.7 0.1 0.74 9.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EGE07885.1 - 0.0046 16.1 0.4 0.1 11.6 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGE07885.1 - 0.0076 15.4 1.3 0.51 9.4 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EGE07885.1 - 0.0077 16.7 0.0 0.73 10.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 EGE07885.1 - 0.011 15.3 0.1 0.55 9.8 0.1 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGE07885.1 - 0.014 14.7 0.0 4 6.6 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGE07885.1 - 0.042 12.6 2.6 0.33 9.6 0.1 2.9 3 0 0 3 3 3 0 HI0933-like protein DUF4147 PF13660.6 EGE07885.1 - 0.08 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Arf PF00025.21 EGE07887.1 - 1.8e-73 245.7 0.1 2.2e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGE07887.1 - 3.9e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGE07887.1 - 8.6e-12 44.9 0.0 9.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGE07887.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGE07887.1 - 2.6e-11 43.3 1.5 3e-07 29.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGE07887.1 - 2.6e-11 43.3 0.0 3.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGE07887.1 - 0.00016 21.7 0.0 0.00044 20.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGE07887.1 - 0.033 13.5 0.3 0.053 12.8 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF3613 PF12266.8 EGE07890.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Fructosamin_kin PF03881.14 EGE07890.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.16 EGE07891.1 - 3.7e-23 82.0 21.6 5.1e-23 81.6 21.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CD20 PF04103.15 EGE07891.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.6 2 1 0 2 2 2 0 CD20-like family Chordopox_A13L PF05961.11 EGE07891.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Peptidase_U4 PF03419.13 EGE07891.1 - 1.2 8.4 11.4 0.16 11.2 5.9 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DHHC PF01529.20 EGE07892.1 - 2.1e-32 112.0 5.9 2.1e-32 112.0 5.9 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2254 PF10011.9 EGE07892.1 - 0.033 13.0 0.2 0.05 12.4 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Acetyltransf_3 PF13302.7 EGE07893.1 - 9.4e-27 94.4 0.1 1.5e-26 93.7 0.0 1.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE07893.1 - 0.00056 20.1 0.0 0.00077 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGE07893.1 - 0.0021 17.7 0.0 0.005 16.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EGE07894.1 - 1.8e-72 243.9 0.0 2.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE07894.1 - 4.6e-45 153.9 0.0 7.2e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE07894.1 - 5.5e-06 25.9 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 2 2 2 1 Kinase-like POLO_box PF00659.18 EGE07894.1 - 0.01 16.0 0.0 0.045 13.9 0.0 2.1 2 0 0 2 2 2 0 POLO box duplicated region Haspin_kinase PF12330.8 EGE07894.1 - 0.011 14.7 0.2 0.021 13.8 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGE07894.1 - 0.045 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGE07894.1 - 0.052 12.3 0.0 0.052 12.3 0.0 2.0 2 1 0 2 2 2 0 Fungal protein kinase OPA3 PF07047.12 EGE07895.1 - 1.3e-48 163.9 1.7 1.8e-48 163.4 1.7 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 EGE07895.1 - 0.00093 19.7 0.3 0.00093 19.7 0.3 2.1 2 0 0 2 2 2 1 Mediator complex protein DUF4472 PF14739.6 EGE07895.1 - 0.59 10.9 7.8 0.3 11.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) TPD52 PF04201.15 EGE07895.1 - 2.5 7.7 8.0 0.17 11.5 0.9 2.1 2 0 0 2 2 2 0 Tumour protein D52 family APG6_N PF17675.1 EGE07895.1 - 8.9 6.8 14.8 0.67 10.5 5.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Myosin_head PF00063.21 EGE07896.1 - 3.8e-241 802.0 4.7 4.6e-241 801.8 4.7 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGE07896.1 - 3.2e-50 170.4 0.0 5.7e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGE07896.1 - 9.7e-12 44.3 0.0 2.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGE07896.1 - 2.5e-09 36.7 0.0 7.8e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGE07896.1 - 4e-09 36.2 0.0 1e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EGE07896.1 - 0.0095 15.7 8.7 0.5 10.3 0.6 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 EGE07896.1 - 0.012 15.9 0.0 0.041 14.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EGE07896.1 - 0.016 15.6 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EGE07896.1 - 0.021 14.3 0.5 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TrwB_AAD_bind PF10412.9 EGE07896.1 - 0.15 10.9 0.1 0.31 9.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 EGE07896.1 - 0.16 12.1 0.2 5.5 7.1 0.0 3.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EGE07896.1 - 0.19 11.6 0.0 0.49 10.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF4229 PF14012.6 EGE07897.1 - 0.0024 17.9 0.1 0.0064 16.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) RSN1_TM PF13967.6 EGE07897.1 - 0.1 12.4 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport CBP_BcsF PF11120.8 EGE07897.1 - 0.58 10.3 1.7 1.2 9.3 1.7 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF p450 PF00067.22 EGE07898.1 - 2.9e-18 65.9 0.0 8.1e-10 38.0 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.6 EGE07899.1 - 7.4e-18 64.9 0.3 1.2e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE07899.1 - 8.1e-11 42.5 0.0 2.4e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE07899.1 - 4.6e-08 33.0 0.0 9.9e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07899.1 - 1.8e-07 31.8 0.2 2.5e-06 28.1 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07899.1 - 3.1e-07 31.0 0.0 6.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGE07899.1 - 0.0035 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EGE07899.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGE07899.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EGE07899.1 - 0.02 14.4 0.0 0.065 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EGE07899.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EGE07899.1 - 0.15 12.0 0.0 8.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain DUF4620 PF15399.6 EGE07900.1 - 0.061 13.7 0.1 0.092 13.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) ABC_membrane PF00664.23 EGE07901.1 - 1.5e-88 297.0 28.0 3.9e-48 164.5 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE07901.1 - 1.2e-59 200.7 0.0 1.7e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE07901.1 - 5.2e-16 58.8 4.1 1.6e-05 24.5 0.0 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGE07901.1 - 7.5e-09 35.2 1.1 0.0012 18.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE07901.1 - 1.1e-07 32.4 0.1 0.0015 18.9 0.0 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGE07901.1 - 5.1e-07 30.1 3.8 0.009 16.3 0.3 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGE07901.1 - 6.6e-06 25.8 0.1 0.052 13.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EGE07901.1 - 1.3e-05 25.8 0.3 0.0089 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGE07901.1 - 1.3e-05 25.2 5.7 0.3 10.9 0.2 4.4 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGE07901.1 - 1.6e-05 24.9 0.1 0.27 11.1 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 EGE07901.1 - 0.00014 22.4 0.1 0.8 10.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EGE07901.1 - 0.00064 18.6 2.6 0.12 11.2 0.8 3.3 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 EGE07901.1 - 0.0017 18.2 1.2 1.3 8.6 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EGE07901.1 - 0.0028 17.8 0.7 1.4 9.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EGE07901.1 - 0.0045 17.2 0.1 1.1 9.6 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EGE07901.1 - 0.0048 16.3 0.1 2.5 7.4 0.0 2.7 2 0 0 2 2 2 1 KaiC DUF3987 PF13148.6 EGE07901.1 - 0.0082 15.2 0.1 3.5 6.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 EGE07901.1 - 0.0093 16.0 1.3 2.6 8.2 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.20 EGE07901.1 - 0.011 15.7 1.0 6 6.7 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_5 PF07728.14 EGE07901.1 - 0.012 15.7 0.2 1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGE07901.1 - 0.015 15.0 0.9 5.9 6.6 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.17 EGE07901.1 - 0.016 15.3 1.9 0.92 9.5 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA PF00004.29 EGE07901.1 - 0.019 15.4 0.0 1.3 9.5 0.0 3.4 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGE07901.1 - 0.021 15.2 0.1 15 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EGE07901.1 - 0.025 14.3 0.7 2.2 8.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 EGE07901.1 - 0.045 12.9 0.1 0.69 9.0 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_30 PF13604.6 EGE07901.1 - 0.046 13.4 1.9 12 5.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EGE07901.1 - 0.09 12.7 0.3 35 4.3 0.1 3.4 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 EGE07901.1 - 0.093 12.2 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IspD PF01128.19 EGE07901.1 - 0.11 12.2 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Cytidylate_kin PF02224.18 EGE07901.1 - 0.11 12.2 0.1 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 EGE07901.1 - 0.14 11.4 0.0 14 4.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EGE07901.1 - 0.16 11.3 0.1 20 4.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Guanylate_kin PF00625.21 EGE07901.1 - 0.19 11.4 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase TniB PF05621.11 EGE07901.1 - 0.23 10.9 0.5 10 5.5 0.0 3.3 4 0 0 4 4 4 0 Bacterial TniB protein AcrZ PF10766.9 EGE07901.1 - 0.4 10.3 2.8 0.38 10.3 0.1 2.3 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ MFS_1 PF07690.16 EGE07902.1 - 4.5e-31 108.0 45.6 4.5e-31 108.0 45.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 EGE07903.1 - 7.2e-45 153.6 0.0 8.6e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ric8 PF10165.9 EGE07905.1 - 6.1e-130 434.3 0.0 7.1e-130 434.1 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.13 EGE07906.1 - 3.6e-13 49.5 0.4 4.3e-13 49.3 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.24 EGE07907.1 - 9e-141 469.8 15.3 1e-140 469.6 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE07907.1 - 8.9e-28 97.2 26.2 2.1e-24 86.2 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 EGE07907.1 - 0.00075 17.8 0.7 0.27 9.4 0.0 2.3 2 0 0 2 2 2 2 BT1 family UPF0014 PF03649.13 EGE07907.1 - 3.7 6.8 9.1 0.32 10.3 2.8 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0014) Glyco_hydro_25 PF01183.20 EGE07909.1 - 4.4e-40 137.8 0.0 5.1e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Rif1_N PF12231.8 EGE07910.1 - 2.8e-127 424.8 0.2 5e-127 424.0 0.2 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal RhoGEF67_u2 PF16614.5 EGE07910.1 - 0.051 13.6 1.4 0.17 11.9 0.0 2.6 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 DUF5538 PF17692.1 EGE07910.1 - 0.18 11.9 3.7 0.2 11.7 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5538) Aldose_epim PF01263.20 EGE07912.1 - 1.1e-38 133.3 0.0 1.3e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase BclA_C PF18573.1 EGE07912.1 - 0.064 13.2 0.3 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 BclA C-terminal domain MFS_1 PF07690.16 EGE07913.1 - 4.4e-24 85.1 27.8 4.4e-24 85.1 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAHP_synth_2 PF01474.16 EGE07915.1 - 2.8e-205 681.9 0.0 3.2e-205 681.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family PLA2_B PF01735.18 EGE07917.1 - 8.5e-195 647.8 0.3 1e-194 647.6 0.3 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain adh_short_C2 PF13561.6 EGE07919.1 - 7.2e-59 199.2 0.2 8.2e-59 199.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE07919.1 - 4.4e-50 169.9 0.9 5.6e-50 169.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE07919.1 - 3.6e-16 59.6 0.2 4.8e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE07919.1 - 0.0018 17.8 0.1 0.0025 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGE07919.1 - 0.002 17.6 0.1 0.0038 16.7 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase GGACT PF06094.12 EGE07920.1 - 1.8e-15 57.6 0.2 2.1e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Piwi PF02171.17 EGE07921.1 - 5.6e-73 245.8 0.0 8.2e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGE07921.1 - 1e-16 61.8 0.0 1.8e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGE07921.1 - 1.6e-12 46.8 0.1 5.5e-12 45.2 0.1 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EGE07921.1 - 1.1e-07 32.1 0.0 3.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EGE07921.1 - 1.9e-06 27.7 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGE07921.1 - 0.0034 17.6 0.0 0.0091 16.2 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Ribophorin_II PF05817.14 EGE07923.1 - 5.5e-06 25.2 0.0 7.1e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ORC6 PF05460.13 EGE07924.1 - 0.14 11.4 4.2 0.17 11.1 4.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) EVE PF01878.18 EGE07926.1 - 4.6e-46 156.4 1.9 6.1e-46 156.0 0.1 1.9 2 0 0 2 2 2 1 EVE domain DUF4551 PF15087.6 EGE07926.1 - 2.1 7.1 10.3 2.9 6.6 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Methyltransf_PK PF05891.12 EGE07927.1 - 3.8e-66 222.7 0.0 6.2e-66 222.1 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EGE07927.1 - 5.2e-08 32.4 0.1 1.3e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGE07927.1 - 4.6e-06 27.2 0.0 1.4e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE07927.1 - 0.00015 22.3 0.0 0.00035 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE07927.1 - 0.0016 19.2 0.0 0.0044 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 EGE07927.1 - 0.027 15.1 0.0 0.045 14.4 0.0 1.3 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Sec23_helical PF04815.15 EGE07927.1 - 0.027 14.3 0.1 0.46 10.3 0.1 2.1 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Aldedh PF00171.22 EGE07928.1 - 2.3e-182 606.6 3.2 2.6e-182 606.5 3.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGE07928.1 - 0.00087 18.8 0.0 0.0037 16.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) GAIN PF16489.5 EGE07928.1 - 0.085 12.3 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain bZIP_2 PF07716.15 EGE07933.1 - 2.6e-05 24.2 9.9 5.2e-05 23.2 9.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGE07933.1 - 0.11 12.6 5.6 0.24 11.5 5.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor His_Phos_2 PF00328.22 EGE07936.1 - 6.4e-65 220.0 0.0 7.4e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AhpC-TSA PF00578.21 EGE07938.1 - 7.2e-30 103.5 0.0 1.1e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGE07938.1 - 4.8e-14 52.3 0.0 8.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGE07938.1 - 3e-09 36.5 0.1 5.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.6 EGE07939.1 - 2.3e-16 59.6 10.0 3.2e-10 40.0 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGE07939.1 - 2.6e-14 52.9 0.5 0.00018 21.4 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGE07939.1 - 2.5e-13 49.8 0.7 0.062 13.6 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EGE07939.1 - 2e-11 43.3 0.0 0.028 14.0 0.0 4.1 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EGE07939.1 - 3e-09 36.7 1.9 0.0079 16.2 0.0 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGE07939.1 - 1.4e-05 24.9 9.1 0.0025 17.7 0.0 5.7 7 0 0 7 7 7 1 Kelch motif mRNA_triPase PF02940.15 EGE07940.1 - 1.1e-39 136.5 0.1 1.7e-39 135.9 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Spt20 PF12090.8 EGE07940.1 - 8.2 6.0 28.1 2.8 7.5 6.5 2.4 2 0 0 2 2 2 0 Spt20 family TFB6 PF17110.5 EGE07941.1 - 2e-40 138.3 0.0 3e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRP7 PF12923.7 EGE07942.1 - 6.5e-28 97.2 5.4 6.5e-28 97.2 5.4 2.3 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EGE07942.1 - 9.9e-28 97.0 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 EGE07942.1 - 0.05 13.9 0.4 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) Rad51 PF08423.11 EGE07943.1 - 2e-113 377.9 0.0 2.5e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGE07943.1 - 1.8e-14 53.9 0.0 2.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EGE07943.1 - 8.2e-08 32.7 1.5 1.2e-07 32.2 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EGE07943.1 - 1.6e-07 30.9 0.0 3.5e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 KaiC Phage_HK97_TLTM PF06120.11 EGE07943.1 - 0.0084 15.3 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 2 Tail length tape measure protein DnaB_C PF03796.15 EGE07943.1 - 0.072 12.4 0.1 0.51 9.6 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain FlgM PF04316.13 EGE07943.1 - 0.083 13.3 0.2 22 5.5 0.1 3.5 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM DnaB_bind PF10410.9 EGE07943.1 - 0.086 13.0 0.0 3 8.1 0.0 2.6 1 1 1 2 2 2 0 DnaB-helicase binding domain of primase AAA_24 PF13479.6 EGE07943.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NRD1_2 PF01995.16 EGE07943.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NrpR regulatory domains NRD1 and 2 zf-CCHC PF00098.23 EGE07944.1 - 2.3e-33 112.8 39.4 1.9e-07 30.9 0.9 5.5 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 EGE07944.1 - 7e-06 25.7 29.0 0.29 10.9 0.9 5.6 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 EGE07944.1 - 0.00039 20.3 26.4 0.032 14.2 0.0 5.1 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 EGE07944.1 - 0.016 14.9 0.9 0.016 14.9 0.9 5.4 4 1 2 6 6 6 0 GAG-polyprotein viral zinc-finger UDPGP PF01704.18 EGE07945.1 - 2.1e-57 194.6 0.0 2.7e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGE07945.1 - 0.022 15.1 0.0 0.07 13.5 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EGE07945.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster RPAP1_N PF08621.10 EGE07945.1 - 0.14 11.9 0.1 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 RPAP1-like, N-terminal MPDZ_u10 PF16667.5 EGE07945.1 - 0.15 13.0 1.8 0.27 12.1 0.9 2.0 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Pro_isomerase PF00160.21 EGE07946.1 - 7.9e-33 114.0 0.0 1.2e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGE07946.1 - 2.8e-16 59.1 0.3 5.1e-15 55.1 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE07946.1 - 0.16 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.18 EGE07947.1 - 3.4e-08 33.5 5.8 8.6e-08 32.2 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 EGE07948.1 - 4.3e-33 113.1 0.1 7.5e-33 112.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 EGE07949.1 - 4.2e-14 52.7 0.1 5.8e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGE07949.1 - 2.8e-05 24.7 0.0 5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGE07949.1 - 3.9e-05 23.2 0.0 5.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EGE07949.1 - 0.0029 17.4 0.0 0.0045 16.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 EGE07949.1 - 0.0031 18.2 0.0 0.0051 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE07949.1 - 0.0033 17.0 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGE07949.1 - 0.0047 16.8 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGE07949.1 - 0.012 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 EGE07949.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 EGE07949.1 - 0.03 14.1 0.0 0.08 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 EGE07949.1 - 0.042 14.5 0.0 0.074 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGE07949.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase adh_short PF00106.25 EGE07950.1 - 1.6e-21 76.7 0.2 2.1e-21 76.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE07950.1 - 3.5e-16 59.5 0.0 4.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE07950.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Pro-kuma_activ PF09286.11 EGE07951.1 - 4.6e-37 127.5 0.0 7.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGE07951.1 - 6.3e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family DUF2306 PF10067.9 EGE07952.1 - 1.4e-11 44.8 10.5 1.4e-11 44.8 10.5 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Glyco_tran_28_C PF04101.16 EGE07952.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 EGE07953.1 - 1.3e-09 38.2 0.0 2.4e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family WD40 PF00400.32 EGE07954.1 - 0.0013 19.5 0.0 0.96 10.4 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat VP40 PF07447.12 EGE07954.1 - 0.12 11.5 0.0 0.3 10.2 0.0 1.6 2 0 0 2 2 2 0 Matrix protein VP40 Vps51 PF08700.11 EGE07955.1 - 1.4e-24 86.0 0.0 3.2e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EGE07955.1 - 0.0022 18.2 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EGE07955.1 - 0.013 14.2 0.4 0.019 13.7 0.4 1.1 1 0 0 1 1 1 0 Dor1-like family RMI1_N PF08585.12 EGE07956.1 - 3.9e-61 206.6 0.0 4.4e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_17 PF13431.6 EGE07957.1 - 5.5e-21 73.4 11.8 0.13 12.7 0.0 13.0 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGE07957.1 - 1.5e-18 65.3 45.5 0.032 14.3 0.1 15.5 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGE07957.1 - 1.4e-17 62.7 35.9 0.026 14.3 0.1 13.7 15 1 0 15 15 15 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGE07957.1 - 1.4e-16 60.7 20.9 6.3e-05 23.4 0.1 10.1 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGE07957.1 - 3.9e-15 56.2 33.9 0.0043 17.7 0.2 11.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGE07957.1 - 8e-15 54.2 18.2 0.013 15.2 0.0 9.8 8 1 1 9 9 9 4 TPR repeat TPR_14 PF13428.6 EGE07957.1 - 1.8e-14 53.2 32.1 0.11 13.3 0.0 15.1 13 4 6 19 19 15 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE07957.1 - 3.4e-14 52.9 37.2 0.055 13.8 0.2 12.3 10 3 2 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGE07957.1 - 2.3e-09 36.7 39.1 0.092 13.0 0.4 11.8 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 EGE07957.1 - 3.7e-07 30.4 19.4 0.93 10.3 0.2 12.1 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE07957.1 - 8.6e-05 22.3 8.9 7.5 6.8 0.0 7.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGE07957.1 - 0.0012 19.0 4.7 11 6.2 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3465 PF11948.8 EGE07957.1 - 0.13 12.1 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) ANAPC5 PF12862.7 EGE07957.1 - 0.94 9.6 8.4 2.2 8.4 0.0 5.1 6 2 0 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 EGE07957.1 - 6.1 6.9 18.7 20 5.2 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 EGE07958.1 - 7.6e-23 80.9 0.0 1.7e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EGE07958.1 - 3.5e-08 33.2 4.1 1.9e-06 27.5 1.8 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) EKLF_TAD1 PF16832.5 EGE07958.1 - 0.025 14.5 0.2 0.06 13.2 0.2 1.6 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 Glyco_hydro_42 PF02449.15 EGE07958.1 - 0.074 12.4 0.1 5.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase Xpo1 PF08389.12 EGE07959.1 - 1.4e-13 51.2 4.5 9.1e-08 32.3 0.1 4.2 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 EGE07959.1 - 0.015 15.2 1.3 0.16 11.9 0.0 3.2 4 0 0 4 4 4 0 Importin-beta N-terminal domain GRIM-19 PF06212.12 EGE07960.1 - 3e-22 79.0 0.2 1.1e-21 77.1 0.2 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 EGE07961.1 - 3.2e-24 85.7 0.0 1.1e-22 80.7 0.0 2.4 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase ApbA_C PF08546.11 EGE07961.1 - 0.07 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Peptidase_M16 PF00675.20 EGE07961.1 - 0.19 11.7 0.8 0.41 10.6 0.8 1.5 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Rsc14 PF08586.10 EGE07961.1 - 0.56 11.1 3.3 2.1 9.2 3.3 1.9 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit VID27 PF08553.10 EGE07962.1 - 3.3e-194 644.8 0.0 5e-194 644.2 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EGE07962.1 - 1.8e-75 252.6 0.3 1.8e-75 252.6 0.3 3.3 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 EGE07962.1 - 2e-47 160.0 0.7 8.6e-47 157.9 0.3 2.1 2 0 0 2 2 2 1 VID27 PH-like domain PRP38_assoc PF12871.7 EGE07962.1 - 0.31 11.7 11.6 1.2 9.7 11.6 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TLD PF07534.16 EGE07963.1 - 1.9e-24 86.5 0.0 2.8e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 TLD Adaptin_N PF01602.20 EGE07964.1 - 8.2e-129 430.5 4.2 9.6e-129 430.3 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGE07964.1 - 1.5e-64 216.9 3.4 1.2e-61 207.5 0.4 2.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGE07964.1 - 6.1e-17 61.8 4.7 6.3e-07 29.7 0.0 5.7 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EGE07964.1 - 5.8e-13 47.9 0.3 0.016 15.4 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EGE07964.1 - 0.00075 20.0 5.3 0.7 10.5 0.0 6.0 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.8 EGE07964.1 - 0.0028 17.3 0.3 1.6 8.3 0.0 3.5 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.23 EGE07964.1 - 0.0085 16.1 5.0 9 6.5 0.0 6.0 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGE07964.1 - 0.018 15.2 0.1 3.2 8.0 0.0 3.7 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_60s PF00428.19 EGE07964.1 - 0.84 10.3 10.6 12 6.5 4.8 3.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DEK_C PF08766.11 EGE07965.1 - 0.0085 16.0 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 DEK C terminal domain CDC27 PF09507.10 EGE07965.1 - 0.09 12.2 37.0 0.13 11.7 37.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Evr1_Alr PF04777.13 EGE07966.1 - 7.7e-29 100.1 3.4 1.6e-28 99.1 3.4 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Bd3614-deam PF14439.6 EGE07966.1 - 0.028 14.5 0.1 6.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Coatomer_WDAD PF04053.14 EGE07967.1 - 1.3e-141 472.7 0.0 1.8e-141 472.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EGE07967.1 - 1.9e-108 362.8 0.0 2.9e-108 362.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGE07967.1 - 3.7e-31 106.7 19.1 3.3e-05 24.6 0.2 8.1 8 1 1 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE07967.1 - 1.3e-08 35.0 0.0 0.022 15.1 0.0 5.6 5 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE07967.1 - 0.0013 17.4 0.8 1.3 7.6 0.0 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.20 EGE07967.1 - 0.0041 17.0 0.2 0.34 10.8 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS DUF966 PF06136.13 EGE07968.1 - 5.7 6.5 11.9 9.3 5.9 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Phytase-like PF13449.6 EGE07969.1 - 9.1e-41 140.7 0.1 1.2e-40 140.3 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Clr5 PF14420.6 EGE07971.1 - 5.3e-21 74.6 3.1 9.5e-21 73.8 0.6 2.6 2 0 0 2 2 2 1 Clr5 domain Het-C PF07217.11 EGE07972.1 - 4.2e-244 811.3 0.0 5.2e-244 811.0 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2828 PF11443.8 EGE07973.1 - 8.1e-234 777.4 0.4 9.7e-234 777.2 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.19 EGE07974.1 - 7.4e-60 202.7 0.1 1.4e-59 201.8 0.1 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGE07974.1 - 6e-35 120.0 0.0 9.8e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Mannosidase_ig PF17786.1 EGE07975.1 - 2.9e-16 59.9 0.3 6.6e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EGE07975.1 - 1.3e-12 48.4 0.0 1.4e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EGE07975.1 - 1.2e-05 25.3 0.0 4.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EGE07975.1 - 3.3e-05 23.2 0.6 0.00012 21.3 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EGE07975.1 - 0.00042 20.0 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain ADH_N PF08240.12 EGE07976.1 - 1.7e-32 111.6 2.6 2.4e-32 111.1 0.3 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGE07976.1 - 1.8e-23 83.0 0.0 3.5e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EGE07976.1 - 2.4e-07 30.5 0.1 5.2e-07 29.4 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EGE07976.1 - 0.00019 22.5 0.0 0.00055 21.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGE07976.1 - 0.0014 17.9 0.2 0.0024 17.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGE07976.1 - 0.0051 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.19 EGE07976.1 - 0.015 15.4 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EGE07976.1 - 0.027 15.2 0.0 0.059 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 EGE07976.1 - 0.029 13.6 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE07976.1 - 0.066 11.9 0.1 0.091 11.4 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.21 EGE07976.1 - 0.079 13.0 0.3 0.67 10.0 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PrmA PF06325.13 EGE07976.1 - 0.088 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.22 EGE07977.1 - 1.1e-40 138.9 0.0 1.5e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE07977.1 - 1.7e-28 99.3 0.0 2.3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE07977.1 - 6.1e-12 45.3 0.0 2.4e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE07977.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGE07977.1 - 0.00028 20.3 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGE07977.1 - 0.00032 20.3 0.0 0.0019 17.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE07977.1 - 0.0042 17.0 0.0 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGE07977.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.12 EGE07977.1 - 0.011 15.7 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGE07977.1 - 0.023 15.2 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGE07977.1 - 0.024 14.8 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGE07977.1 - 0.036 13.8 0.0 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGE07977.1 - 0.057 13.8 0.2 0.44 10.9 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGE07977.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGE07977.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region bZIP_1 PF00170.21 EGE07979.1 - 3.5e-06 27.0 4.8 7.3e-06 26.0 4.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor TilS PF09179.11 EGE07981.1 - 7 7.2 7.1 12 6.5 0.4 3.1 3 0 0 3 3 3 0 TilS substrate binding domain AIM24 PF01987.17 EGE07982.1 - 3.3e-54 183.8 0.4 3.8e-54 183.5 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 eIF-5_eIF-2B PF01873.17 EGE07983.1 - 6.4e-41 138.9 0.1 1.1e-40 138.1 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 EGE07983.1 - 0.35 10.7 2.8 12 5.8 0.0 2.7 3 0 0 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 EGE07983.1 - 1.2 9.6 7.4 1.1 9.6 0.3 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain DUF2894 PF11445.8 EGE07983.1 - 1.2 9.6 5.6 26 5.2 5.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) MFS_1 PF07690.16 EGE07985.1 - 2e-06 27.0 0.0 2.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EGE07985.1 - 0.00058 19.4 1.0 0.00075 19.1 1.0 1.1 1 0 0 1 1 1 1 Nodulin-like PRAS PF15798.5 EGE07985.1 - 0.097 13.3 0.6 0.13 12.9 0.6 1.2 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 IPK PF03770.16 EGE07986.1 - 2.3e-29 102.7 0.2 5.8e-26 91.6 0.0 3.0 2 2 0 2 2 2 1 Inositol polyphosphate kinase Pam17 PF08566.10 EGE07986.1 - 0.049 13.5 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 LRR_4 PF12799.7 EGE07987.1 - 9.1e-24 83.2 42.0 3.5e-05 24.1 1.5 9.1 8 1 0 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGE07987.1 - 9e-20 70.2 43.3 6.3e-07 29.1 3.2 7.9 5 1 2 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 EGE07987.1 - 1e-10 41.4 10.4 5.2e-05 22.8 1.0 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EGE07987.1 - 4.5 7.6 29.4 1.8 8.8 1.3 9.0 9 1 0 10 10 10 0 Leucine Rich repeat adh_short_C2 PF13561.6 EGE07989.1 - 3e-61 207.0 0.1 3.4e-61 206.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE07989.1 - 2.7e-41 141.2 0.2 3.2e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE07989.1 - 3.6e-14 53.1 0.1 5.2e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 KR domain LktC PF06261.11 EGE07989.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 1 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Clathrin PF00637.20 EGE07990.1 - 2e-20 73.1 2.8 1.2e-17 64.1 0.8 2.8 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGE07990.1 - 4.9e-18 65.1 0.5 1.1e-17 64.0 0.5 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGE07990.1 - 5.1e-07 29.6 8.1 9.6e-07 28.7 8.1 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EGE07990.1 - 4.5e-06 26.4 6.4 8.6e-06 25.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE07990.1 - 0.00021 21.2 5.7 0.00042 20.2 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGE07990.1 - 0.00045 20.5 6.4 0.00088 19.6 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.6 EGE07990.1 - 0.0014 18.2 1.3 0.0023 17.6 0.1 2.0 2 0 0 2 2 2 1 TPR repeat WD40_like PF17005.5 EGE07990.1 - 0.0035 16.7 0.2 0.07 12.4 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain HPS3_N PF14761.6 EGE07990.1 - 0.0047 16.5 0.0 0.024 14.2 0.0 2.2 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 TPR_14 PF13428.6 EGE07990.1 - 0.006 17.3 0.0 0.32 11.9 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 EGE07990.1 - 0.0078 16.5 4.7 0.016 15.5 4.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain TPR_8 PF13181.6 EGE07990.1 - 0.026 14.7 0.1 1.3 9.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EGE07990.1 - 0.056 13.3 5.5 0.11 12.4 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGE07990.1 - 0.072 13.2 0.7 0.71 10.1 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGE07990.1 - 0.1 12.9 1.1 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 EGE07990.1 - 0.53 10.4 2.3 1.5 8.9 2.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGE07990.1 - 1.2 9.2 6.5 3 8.0 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TPR_1 PF00515.28 EGE07990.1 - 1.4 8.9 3.5 3.2 7.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 EGE07991.1 - 0.0011 19.9 0.1 0.0061 17.5 0.1 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.21 EGE07991.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 EGE07991.1 - 0.15 10.7 0.3 0.25 9.9 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 FAD_binding_3 PF01494.19 EGE07992.1 - 9.5e-23 81.0 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGE07992.1 - 9.4e-07 28.3 1.1 0.00046 19.5 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE07992.1 - 6.3e-06 26.7 0.5 0.00064 20.2 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE07992.1 - 0.00036 20.2 1.5 0.0056 16.3 0.8 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE07992.1 - 0.0026 16.9 0.7 0.0048 16.0 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGE07992.1 - 0.0051 17.0 0.4 0.012 15.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EGE07992.1 - 0.049 12.7 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 EGE07992.1 - 0.08 11.8 0.1 5.2 5.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGE07992.1 - 0.12 11.7 0.9 6.3 6.0 0.2 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGE07992.1 - 0.16 11.9 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RAD51_interact PF15696.5 EGE07993.1 - 0.037 14.1 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 RAD51 interacting motif Polysacc_deac_1 PF01522.21 EGE07994.1 - 2.5e-27 95.2 0.0 5.2e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EGE07994.1 - 0.0003 21.2 16.5 0.00094 19.6 16.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein DUF2334 PF10096.9 EGE07994.1 - 0.051 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Trypan_PARP PF05887.11 EGE07994.1 - 4.7 7.2 8.8 10 6.1 8.8 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RTP1_C1 PF10363.9 EGE07996.1 - 2.1e-29 102.0 0.1 2.7e-28 98.4 0.0 2.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGE07996.1 - 2.1e-10 40.1 0.0 4.6e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 FliT PF05400.13 EGE07996.1 - 0.27 12.1 1.8 0.47 11.3 0.4 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DBR1 PF05011.13 EGE07997.1 - 4.6e-43 147.0 0.0 1.2e-42 145.6 0.0 1.8 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGE07997.1 - 1.6e-06 28.8 1.9 2.9e-06 27.9 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Polysacc_deac_3 PF15421.6 EGE07997.1 - 0.12 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase Rpr2 PF04032.16 EGE07998.1 - 8.5e-12 45.2 3.0 8.5e-12 45.2 3.0 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.6 EGE07998.1 - 0.022 14.2 1.2 0.048 13.1 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-ZPR1 PF03367.13 EGE07999.1 - 1.8e-50 170.9 0.0 2.3e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain zinc_ribbon_2 PF13240.6 EGE07999.1 - 2.1 8.1 4.7 0.86 9.4 1.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Pro_isomerase PF00160.21 EGE08000.1 - 2.3e-34 119.0 0.0 3.7e-34 118.3 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 EGE08001.1 - 5.5e-13 49.5 0.0 1.7e-12 48.0 0.0 1.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 EGE08003.1 - 1.7e-29 101.8 0.0 2.7e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EGE08003.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.15 EGE08004.1 - 3.2e-09 36.8 0.0 4.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Nif11 PF07862.11 EGE08004.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Nif11 domain APH PF01636.23 EGE08005.1 - 4.3e-08 33.4 2.3 1.4e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGE08005.1 - 8.9e-07 28.5 0.0 2.7e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGE08005.1 - 0.00015 21.2 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGE08005.1 - 0.003 17.2 0.3 0.017 14.7 0.0 2.2 3 0 0 3 3 3 1 Choline/ethanolamine kinase HSDR_N_2 PF13588.6 EGE08005.1 - 0.011 15.8 0.1 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) UBA2_C PF16195.5 EGE08005.1 - 0.31 11.8 0.0 0.31 11.8 0.0 2.8 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus SR-25 PF10500.9 EGE08005.1 - 0.32 10.6 12.6 0.32 10.6 8.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3584 PF12128.8 EGE08005.1 - 9.7 3.6 11.2 14 3.0 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) adh_short_C2 PF13561.6 EGE08006.1 - 4.3e-32 111.6 2.7 5.1e-31 108.0 2.7 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE08006.1 - 1e-30 106.7 4.3 2.3e-16 59.8 0.1 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGE08006.1 - 5.8e-08 32.9 0.8 2.1e-07 31.0 0.0 2.2 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EGE08006.1 - 0.0002 20.9 0.1 0.0005 19.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGE08006.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGE08006.1 - 0.0087 15.3 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein ThiF PF00899.21 EGE08007.1 - 1.3e-73 247.4 0.0 1.8e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EGE08007.1 - 1.2e-21 77.1 0.1 3e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EGE08007.1 - 3.9e-08 33.5 1.0 0.0013 18.8 0.1 2.4 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGE08007.1 - 0.00021 21.7 0.0 0.00077 19.9 0.0 2.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGE08007.1 - 0.02 14.9 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EGE08007.1 - 0.053 14.1 0.0 7.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E2_bind PF08825.10 EGE08007.1 - 0.13 12.4 0.7 0.27 11.4 0.2 1.8 2 0 0 2 2 2 0 E2 binding domain Q_salvage PF10343.9 EGE08008.1 - 2.8e-133 443.8 0.0 3.3e-133 443.6 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ORC6 PF05460.13 EGE08009.1 - 8.9e-44 150.2 7.7 2.8e-32 112.4 10.6 2.1 1 1 1 2 2 2 2 Origin recognition complex subunit 6 (ORC6) DUF2336 PF10098.9 EGE08009.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Senescence_reg PF04520.13 EGE08009.1 - 0.1 13.5 3.1 0.35 11.7 0.7 2.2 2 0 0 2 2 2 0 Senescence regulator DUF4795 PF16043.5 EGE08011.1 - 0.012 15.3 1.0 0.015 14.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) PspA_IM30 PF04012.12 EGE08011.1 - 0.02 14.5 1.4 0.072 12.7 1.4 1.7 1 1 0 1 1 1 0 PspA/IM30 family DUF5082 PF16888.5 EGE08011.1 - 0.029 14.7 0.5 0.045 14.0 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 EGE08011.1 - 0.05 14.1 0.2 0.19 12.2 0.1 1.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 EGE08011.1 - 0.1 12.4 1.9 0.72 9.7 2.0 2.0 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 EGE08011.1 - 0.29 11.4 1.5 3.3 8.0 1.7 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Amidase PF01425.21 EGE08012.1 - 7.1e-89 298.8 0.0 9.7e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.13 EGE08013.1 - 9.2e-36 123.1 3.2 1.5e-35 122.4 2.9 1.6 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 CFEM PF05730.11 EGE08015.1 - 1.9e-15 56.7 7.7 2.7e-15 56.2 7.7 1.2 1 0 0 1 1 1 1 CFEM domain MGC-24 PF05283.11 EGE08015.1 - 0.062 13.8 5.6 0.089 13.2 5.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Citrate_bind PF16114.5 EGE08017.1 - 5.5e-87 289.8 0.0 7.8e-87 289.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EGE08017.1 - 1.7e-07 31.0 0.0 2.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EGE08017.1 - 0.062 11.4 0.0 0.087 10.9 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EGE08018.1 - 1.3e-19 70.5 0.0 1.7e-16 60.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EGE08018.1 - 2.2e-18 66.7 0.1 8.9e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGE08018.1 - 7.4e-13 48.6 0.1 1.3e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGE08018.1 - 1.3e-05 25.0 0.1 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.19 EGE08019.1 - 7.5e-39 132.1 0.0 9.5e-39 131.8 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 EGE08020.1 - 6.3e-78 261.9 0.0 7.7e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EGE08020.1 - 0.00098 19.1 0.0 0.17 11.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EGE08020.1 - 0.0018 17.3 0.1 0.0039 16.2 0.0 1.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGE08020.1 - 0.0022 18.1 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EGE08020.1 - 0.0097 14.9 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Fer4_NifH PF00142.18 EGE08020.1 - 0.017 14.6 0.2 0.054 12.9 0.2 1.8 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KTI12 PF08433.10 EGE08020.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EGE08020.1 - 0.027 14.8 0.0 0.042 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 EGE08020.1 - 0.052 14.0 0.2 0.13 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGE08020.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGE08020.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGE08020.1 - 0.075 13.4 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGE08020.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGE08020.1 - 0.095 13.2 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EGE08020.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EGE08020.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EGE08021.1 - 9.8e-12 45.2 3.1 0.13 13.1 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat FHA PF00498.26 EGE08021.1 - 0.14 12.5 0.0 0.73 10.2 0.0 2.1 2 0 0 2 2 2 0 FHA domain HNH_2 PF13391.6 EGE08022.1 - 2.6e-08 33.9 0.0 7.9e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 HNH endonuclease DUF2457 PF10446.9 EGE08022.1 - 0.14 11.3 2.9 0.2 10.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RTA1 PF04479.13 EGE08023.1 - 5.6e-53 179.6 7.1 8.4e-53 179.0 7.1 1.3 1 0 0 1 1 1 1 RTA1 like protein BSP_II PF05432.11 EGE08025.1 - 0.014 15.1 5.2 0.018 14.7 5.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4632 PF15451.6 EGE08025.1 - 0.1 12.7 0.3 0.2 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Myc_N PF01056.18 EGE08025.1 - 0.34 10.7 5.2 0.46 10.3 5.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ofd1_CTDD PF10637.9 EGE08026.1 - 8.5e-94 313.7 0.0 4.9e-91 304.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EGE08026.1 - 6.4e-25 87.6 0.0 2.6e-24 85.7 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EGE08026.1 - 8.2e-14 52.3 0.0 1.7e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BUD22 PF09073.10 EGE08026.1 - 6.4 6.0 15.5 0.17 11.2 6.9 2.2 2 0 0 2 2 2 0 BUD22 APH PF01636.23 EGE08027.1 - 4.3e-09 36.6 0.0 1.5e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Clathrin_H_link PF13838.6 EGE08029.1 - 0.12 12.4 0.7 0.98 9.4 0.6 2.2 2 0 0 2 2 2 0 Clathrin-H-link COesterase PF00135.28 EGE08030.1 - 5.1e-80 269.8 0.0 6.6e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGE08030.1 - 2.1e-07 31.0 0.2 2.3e-06 27.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGE08030.1 - 0.12 11.9 0.3 0.19 11.2 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Endopep_inhib PF16800.5 EGE08030.1 - 0.22 11.5 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor p450 PF00067.22 EGE08032.1 - 1.8e-66 224.8 0.0 2.4e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 EGE08032.1 - 0.019 15.0 0.5 0.038 14.0 0.5 1.4 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit FAD_binding_4 PF01565.23 EGE08033.1 - 3.2e-34 117.6 6.8 1.1e-33 115.8 6.3 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGE08033.1 - 0.0058 16.7 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EGE08034.1 - 2.3e-09 37.1 6.1 6.8e-06 25.9 4.6 2.6 1 1 1 2 2 2 2 FAD binding domain DRMBL PF07522.14 EGE08035.1 - 2.2e-33 114.7 0.0 4.6e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGE08035.1 - 4.4e-05 23.1 0.0 0.00015 21.4 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGE08035.1 - 0.032 14.2 0.2 0.066 13.2 0.2 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.22 EGE08036.1 - 3.9e-18 64.9 0.8 5.1e-18 64.5 0.8 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGE08036.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF402 PF04167.13 EGE08036.1 - 0.054 13.7 0.4 0.074 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF402) Methyltransf_11 PF08241.12 EGE08037.1 - 7.2e-07 29.8 0.0 1.5e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08037.1 - 0.066 13.9 0.0 0.18 12.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain zf-BED PF02892.15 EGE08038.1 - 0.0011 19.0 5.5 0.31 11.1 0.3 2.6 2 0 0 2 2 2 2 BED zinc finger SH3BGR PF04908.15 EGE08040.1 - 0.00049 20.2 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EGE08040.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Pkinase PF00069.25 EGE08041.1 - 9e-24 84.2 0.0 1.4e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08041.1 - 3.1e-08 33.2 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE08041.1 - 0.006 15.4 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE08041.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGE08041.1 - 0.062 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribul_P_3_epim PF00834.19 EGE08042.1 - 1.5e-61 207.3 0.0 2.2e-60 203.5 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Melibiase PF02065.18 EGE08042.1 - 0.0056 15.7 0.1 0.29 10.1 0.0 2.2 2 0 0 2 2 2 2 Melibiase ThiG PF05690.14 EGE08042.1 - 0.06 12.7 0.4 0.083 12.2 0.4 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG zf-C2H2 PF00096.26 EGE08043.1 - 0.56 10.8 15.1 4.7 7.9 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE08043.1 - 0.57 11.2 13.6 0.42 11.6 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger ABC2_membrane PF01061.24 EGE08045.1 - 2.2e-86 288.6 59.7 1.7e-44 151.8 19.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGE08045.1 - 2.1e-34 119.0 0.0 2e-16 60.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGE08045.1 - 8.5e-33 112.1 10.1 7.7e-31 105.8 0.1 3.7 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 EGE08045.1 - 1.7e-18 67.0 0.0 4.1e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EGE08045.1 - 9.2e-06 25.0 53.6 0.005 16.0 19.6 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 EGE08045.1 - 4.8e-05 23.0 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE08045.1 - 8.1e-05 23.1 0.2 0.0018 18.7 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGE08045.1 - 0.00012 22.0 0.1 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EGE08045.1 - 0.00045 20.4 0.1 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGE08045.1 - 0.0011 19.6 0.1 0.013 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGE08045.1 - 0.0085 15.9 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGE08045.1 - 0.024 14.4 1.8 0.046 13.5 0.1 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain SMC_N PF02463.19 EGE08045.1 - 0.048 13.1 0.0 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EGE08045.1 - 0.12 12.0 1.3 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MS_channel PF00924.18 EGE08047.1 - 8.2e-25 87.6 2.4 2.1e-24 86.2 2.4 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel Ferlin_C PF16165.5 EGE08047.1 - 0.43 10.5 0.0 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 Ferlin C-terminus Tubulin PF00091.25 EGE08049.1 - 5.1e-65 219.4 0.0 6.7e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGE08049.1 - 2e-44 150.8 0.0 3.1e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGE08049.1 - 0.00037 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Mito_carr PF00153.27 EGE08050.1 - 6.9e-64 211.8 2.7 5.2e-20 71.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGE08050.1 - 0.11 11.7 0.2 4.6 6.3 0.0 3.2 4 0 0 4 4 4 0 Gammaproteobacterial serine protease TauD PF02668.16 EGE08051.1 - 5e-44 151.1 0.0 7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EGE08051.1 - 1e-06 29.3 0.0 2.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EGE08051.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 CsiD PhyH PF05721.13 EGE08051.1 - 0.14 12.4 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.24 EGE08052.1 - 1.1e-18 67.2 0.0 1.2e-16 60.7 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGE08052.1 - 6e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGE08052.1 - 0.00055 20.2 0.0 0.072 13.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGE08052.1 - 0.0054 17.2 0.0 0.056 13.9 0.0 2.5 2 2 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGE08052.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family OPT PF03169.15 EGE08053.1 - 7.9e-176 586.3 55.1 9e-176 586.1 55.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 EGE08053.1 - 0.096 12.0 1.3 0.34 10.2 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Beta_elim_lyase PF01212.21 EGE08056.1 - 6.8e-67 225.8 0.0 8.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase CN_hydrolase PF00795.22 EGE08057.1 - 2.2e-43 148.5 0.1 2.8e-43 148.1 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Pkinase PF00069.25 EGE08059.1 - 5.6e-66 222.6 0.0 1.3e-65 221.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08059.1 - 1.7e-33 116.0 0.0 2.8e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGE08059.1 - 3.6e-09 36.8 0.9 2.9e-08 33.9 0.2 2.7 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGE08059.1 - 0.0006 20.1 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ribonuc_P_40 PF08584.11 EGE08059.1 - 0.0079 15.5 0.7 0.018 14.3 0.7 1.5 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit RIO1 PF01163.22 EGE08059.1 - 0.02 14.5 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGE08059.1 - 0.032 13.6 0.0 0.09 12.1 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGE08059.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE08059.1 - 0.096 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGE08059.1 - 0.22 10.2 1.1 0.55 8.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase TFR_dimer PF04253.15 EGE08060.1 - 2.4e-23 82.5 0.0 3.7e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EGE08060.1 - 2.8e-21 76.1 0.0 4.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EGE08060.1 - 2e-10 40.6 0.5 2.3e-09 37.1 0.4 2.7 2 1 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EGE08060.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_transf_34 PF05637.12 EGE08061.1 - 3.7e-63 213.4 0.0 5.9e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.9 EGE08062.1 - 0.034 14.6 0.0 0.037 14.5 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.18 EGE08063.1 - 1.7e-14 53.4 1.1 4.3e-14 52.1 1.1 1.6 1 1 0 1 1 1 1 BRO1-like domain TAFII55_N PF04658.13 EGE08064.1 - 1.3e-52 177.8 0.3 1.3e-51 174.5 0.0 2.2 2 0 0 2 2 2 1 TAFII55 protein conserved region NinE PF05322.11 EGE08064.1 - 0.057 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NINE Protein AAA_13 PF13166.6 EGE08064.1 - 8.7 4.8 8.9 0.33 9.6 3.0 1.5 2 0 0 2 2 2 0 AAA domain Bromo_TP PF07524.13 EGE08065.1 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGE08065.1 - 0.02 14.9 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LysM PF01476.20 EGE08066.1 - 4.9e-08 32.9 1.0 0.00017 21.6 0.0 3.5 4 0 0 4 4 4 2 LysM domain DUF1153 PF06627.11 EGE08066.1 - 0.028 14.5 0.0 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Ank_2 PF12796.7 EGE08068.1 - 1.6e-36 124.7 0.0 3.4e-11 43.6 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08068.1 - 3.7e-28 97.5 4.6 8e-07 29.5 0.0 6.5 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08068.1 - 7e-25 84.4 4.4 0.04 14.5 0.0 10.0 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EGE08068.1 - 5.2e-18 64.6 4.8 0.14 12.7 0.0 8.1 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EGE08068.1 - 1.5e-16 60.2 5.3 0.003 17.8 0.0 8.5 2 2 7 9 9 9 3 Ankyrin repeats (many copies) F-box-like PF12937.7 EGE08068.1 - 0.096 12.6 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 F-box-like FAD_binding_7 PF03441.14 EGE08070.1 - 4e-80 268.1 1.2 6.2e-80 267.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EGE08070.1 - 6.1e-41 140.2 0.1 1.2e-40 139.2 0.1 1.5 1 0 0 1 1 1 1 DNA photolyase TPH PF13868.6 EGE08070.1 - 0.22 10.0 1.2 0.36 9.3 1.2 1.2 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain GFA PF04828.14 EGE08071.1 - 2.7e-16 59.7 1.3 3.9e-16 59.2 1.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Med16 PF11635.8 EGE08071.1 - 0.19 9.6 0.4 0.21 9.4 0.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 Tmemb_9 PF05434.11 EGE08071.1 - 3.2 7.6 5.9 10 6.0 0.1 2.1 2 0 0 2 2 2 0 TMEM9 APH PF01636.23 EGE08072.1 - 7e-13 49.1 0.0 9.5e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EGE08072.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGE08072.1 - 0.016 14.1 0.1 0.044 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) adh_short PF00106.25 EGE08074.1 - 4.3e-10 39.4 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE08074.1 - 3.6e-08 33.5 0.0 6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGE08074.1 - 1.2e-06 28.3 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.13 EGE08074.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_M36 PF02128.15 EGE08075.1 - 1.3e-160 534.6 2.4 1.6e-160 534.3 2.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EGE08075.1 - 3.1e-17 62.1 2.3 6.7e-17 61.1 2.3 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF5122 PF17164.4 EGE08075.1 - 0.0094 16.2 0.3 0.6 10.5 0.2 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5122) beta-propeller Peptidase_M14 PF00246.24 EGE08076.1 - 1.3e-14 54.8 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGE08076.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 EGE08076.1 - 0.029 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Aldo_ket_red PF00248.21 EGE08077.1 - 2.8e-51 174.4 0.0 4.2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family tRNA-synt_1c PF00749.21 EGE08078.1 - 4.7e-82 275.4 0.0 7.2e-72 241.9 0.0 2.5 2 1 1 3 3 3 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGE08078.1 - 9.8e-36 123.2 0.1 1.5e-35 122.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EGE08078.1 - 0.096 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EGE08078.1 - 0.12 11.6 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain GST_C_3 PF14497.6 EGE08078.1 - 0.13 12.5 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_3 PF00933.21 EGE08079.1 - 2e-65 221.3 0.0 2.2e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MBOAT PF03062.19 EGE08080.1 - 6.3e-27 94.8 2.5 9.6e-27 94.2 2.5 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CCD PF07860.11 EGE08080.1 - 0.1 12.7 0.2 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 WisP family C-Terminal Region Poxvirus_B22R PF04395.12 EGE08080.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein Paramyxo_C PF01692.18 EGE08080.1 - 0.15 11.5 0.3 0.27 10.6 0.3 1.4 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C 5_nucleotid PF05761.14 EGE08081.1 - 0.24 10.3 0.1 0.33 9.8 0.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family CPBP PF02517.16 EGE08082.1 - 3.9e-15 56.0 6.5 3.9e-15 56.0 6.5 2.7 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Suc_Fer-like PF06999.12 EGE08083.1 - 6.2e-58 195.9 0.0 7e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like HofP PF10748.9 EGE08083.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 DNA utilization proteins HofP zf-C2H2_2 PF12756.7 EGE08084.1 - 6.6e-21 74.5 7.0 4.6e-20 71.8 4.8 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGE08084.1 - 0.0041 17.8 5.2 13 6.9 0.5 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EGE08084.1 - 0.0083 16.5 0.0 0.029 14.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Fer4 PF00037.27 EGE08084.1 - 0.48 10.3 0.1 0.48 10.3 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain tRNA-synt_1 PF00133.22 EGE08085.1 - 6.2e-55 186.6 0.0 8.3e-25 87.1 0.1 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGE08085.1 - 4.2e-38 130.7 0.0 6.5e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGE08085.1 - 7.2e-32 110.6 1.4 3.7e-24 85.2 0.0 4.5 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGE08085.1 - 2.2e-14 53.7 0.0 4.1e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGE08085.1 - 2.7e-06 27.0 0.0 0.00042 19.8 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 EGE08085.1 - 0.14 11.6 2.7 4.3 6.9 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Cation_ATPase_C PF00689.21 EGE08086.1 - 0.016 15.0 5.2 0.028 14.1 5.2 1.4 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Polysacc_synt_C PF14667.6 EGE08086.1 - 0.81 9.7 12.3 0.49 10.5 8.6 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PetL PF05115.14 EGE08086.1 - 5.9 6.9 7.1 17 5.5 0.1 2.9 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) DUF2754 PF10953.8 EGE08086.1 - 6.7 7.0 7.2 3.6 7.9 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) 2-Hacid_dh_C PF02826.19 EGE08087.1 - 4e-49 166.4 0.0 6.2e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE08087.1 - 3e-16 59.3 0.0 4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Drf_GBD PF06371.13 EGE08089.1 - 2.5e-69 232.6 0.7 7.7e-69 231.0 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FH2 PF02181.23 EGE08089.1 - 3.2e-61 207.5 0.9 3.2e-61 207.5 0.9 1.6 1 1 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EGE08089.1 - 2.6e-26 92.4 2.2 9.8e-26 90.6 0.9 2.3 1 1 1 2 2 2 1 Diaphanous FH3 Domain Aspzincin_M35 PF14521.6 EGE08090.1 - 0.019 15.5 0.0 0.024 15.2 0.0 1.1 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DUF3886 PF13025.6 EGE08091.1 - 0.069 13.4 0.0 0.069 13.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) TrmE_N PF10396.9 EGE08092.1 - 5.7e-36 123.3 0.0 1.2e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EGE08092.1 - 4.4e-29 102.1 0.0 1.5e-28 100.4 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EGE08092.1 - 6.2e-18 64.9 0.0 1.1e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGE08092.1 - 9.1e-06 25.8 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EGE08092.1 - 2.4e-05 23.9 0.3 0.00017 21.2 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGE08092.1 - 0.00091 18.8 0.0 0.068 12.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Glyco_hydro_3_C PF01915.22 EGE08092.1 - 0.0064 16.5 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.6 EGE08092.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE08092.1 - 0.029 14.3 0.3 0.89 9.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EGE08092.1 - 0.05 14.1 0.1 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 EGE08092.1 - 0.077 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DUF5638 PF18688.1 EGE08092.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) Roc PF08477.13 EGE08092.1 - 0.13 12.5 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_pol_L_2 PF13656.6 EGE08093.1 - 8.6e-34 115.2 0.0 1.2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGE08093.1 - 3.2e-14 52.1 0.0 4.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 EGE08094.1 - 8.6e-07 29.6 0.4 1.4e-06 29.0 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGE08094.1 - 4.3e-06 26.7 0.6 8.7e-06 25.7 0.6 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DUF5301 PF17225.3 EGE08095.1 - 0.019 15.4 1.3 0.044 14.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Abhydrolase_1 PF00561.20 EGE08096.1 - 7.8e-14 51.9 0.1 3.3e-13 49.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE08096.1 - 6.6e-11 41.9 0.0 2.7e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 EGE08096.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TRAPPC9-Trs120 PF08626.11 EGE08097.1 - 0 1424.2 0.0 0 1424.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3684 PF12449.8 EGE08098.1 - 0 1321.0 0.0 0 1320.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EGE08098.1 - 8.9e-05 22.3 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UPF0767 PF15990.5 EGE08098.1 - 0.75 10.0 2.3 2.5 8.3 2.3 1.8 1 0 0 1 1 1 0 UPF0767 family Roughex PF06020.11 EGE08098.1 - 0.81 8.7 3.8 14 4.6 2.0 2.2 2 0 0 2 2 2 0 Drosophila roughex protein WLM PF08325.10 EGE08098.1 - 0.96 9.5 5.5 0.29 11.2 0.7 2.3 2 0 0 2 2 2 0 WLM domain DUF1117 PF06547.12 EGE08098.1 - 1.8 9.2 3.8 0.93 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Pro-kuma_activ PF09286.11 EGE08099.1 - 1.3e-37 129.2 0.2 2.3e-37 128.5 0.2 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGE08099.1 - 0.00045 19.6 0.2 0.0021 17.4 0.0 2.0 2 1 0 2 2 2 1 Subtilase family MATH PF00917.26 EGE08099.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 MATH domain BTB PF00651.31 EGE08101.1 - 0.027 14.7 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain RdRP PF05183.12 EGE08102.1 - 3.5e-180 600.5 0.0 4.4e-180 600.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Lsm_C PF14894.6 EGE08102.1 - 0.13 12.0 0.0 0.62 9.9 0.0 2.2 1 0 0 1 1 1 0 Lsm C-terminal Med6 PF04934.14 EGE08103.1 - 7.4e-40 135.8 0.0 1.7e-39 134.7 0.1 1.5 2 0 0 2 2 2 1 MED6 mediator sub complex component Lysine_decarbox PF03641.14 EGE08104.1 - 1.2e-29 103.0 0.0 1.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGE08104.1 - 0.00088 18.9 1.2 0.0012 18.5 0.1 1.7 2 0 0 2 2 2 1 SLOG cluster4 family LSDAT_prok PF18171.1 EGE08104.1 - 0.031 13.5 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Proteasome PF00227.26 EGE08105.1 - 8.9e-49 165.6 0.4 1.2e-48 165.2 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGE08105.1 - 2.9e-12 46.0 1.1 5e-12 45.3 0.3 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 EGE08105.1 - 0.064 13.1 0.6 29 4.6 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Vps55 PF04133.14 EGE08106.1 - 2.6e-45 153.2 8.9 2.9e-45 153.0 8.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 EGE08106.1 - 0.59 10.6 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Sld7_C PF18596.1 EGE08107.1 - 2.8e-10 40.2 0.0 1.7e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Sld7 C-terminal domain UPF0220 PF05255.11 EGE08108.1 - 4.4e-69 231.3 4.0 5e-69 231.1 4.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.12 EGE08108.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF5337 PF17272.2 EGE08108.1 - 1.5 8.7 4.7 5.3 6.9 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Fes1 PF08609.10 EGE08109.1 - 6.2e-29 100.7 7.2 6.4e-29 100.7 3.3 2.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EGE08109.1 - 6.3e-15 55.3 1.4 2.8e-07 30.8 0.1 2.1 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGE08109.1 - 1.4e-09 38.2 0.1 4.5e-07 30.2 0.0 2.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EGE08109.1 - 2.3e-09 36.7 0.0 0.00031 20.7 0.0 2.9 3 0 0 3 3 2 2 HEAT repeat Arm PF00514.23 EGE08109.1 - 3.8e-07 29.9 0.0 0.027 14.5 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGE08109.1 - 2.4e-05 24.4 0.1 5.5e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGE08109.1 - 0.00046 18.9 0.1 0.00093 17.9 0.0 1.5 2 0 0 2 2 2 1 Adaptin N terminal region SIL1 PF16782.5 EGE08109.1 - 0.0049 16.1 0.0 0.25 10.5 0.0 2.2 1 1 1 2 2 2 1 Nucleotide exchange factor SIL1 TPR_18 PF13512.6 EGE08109.1 - 0.005 17.0 0.2 0.21 11.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat RICTOR_V PF14668.6 EGE08109.1 - 0.0064 16.7 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_N PF03224.14 EGE08109.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGE08109.1 - 0.02 15.0 0.3 0.96 9.6 0.1 2.1 1 1 1 2 2 2 0 V-ATPase subunit H Cytochrom_B562 PF07361.11 EGE08109.1 - 0.24 12.1 2.0 0.68 10.6 0.2 2.2 1 1 0 2 2 2 0 Cytochrome b562 CNDH2_C PF16858.5 EGE08110.1 - 0.019 14.9 1.4 0.021 14.7 1.4 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4746 PF15928.5 EGE08110.1 - 0.052 13.0 0.1 0.058 12.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 EGE08110.1 - 0.063 12.4 5.5 0.067 12.3 5.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 EGE08110.1 - 0.099 13.0 6.0 0.15 12.5 6.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cytomega_UL84 PF06284.11 EGE08110.1 - 0.15 10.5 1.1 0.18 10.2 1.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DNA_pol_phi PF04931.13 EGE08110.1 - 0.4 8.7 3.2 0.41 8.7 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EGE08110.1 - 1.1 9.4 11.0 1.5 9.0 11.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ANAPC15 PF15243.6 EGE08110.1 - 3.3 8.2 13.9 6.7 7.2 13.9 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Actin PF00022.19 EGE08111.1 - 3.1e-100 335.6 0.0 1.4e-99 333.4 0.0 1.7 1 1 0 1 1 1 1 Actin GARS_A PF01071.19 EGE08112.1 - 4.7e-84 281.0 0.0 7.8e-84 280.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EGE08112.1 - 1.8e-35 121.6 0.2 7.8e-34 116.3 0.0 3.0 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EGE08112.1 - 8.1e-35 120.3 0.2 2.6e-34 118.6 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EGE08112.1 - 4.6e-27 94.1 0.7 1.2e-26 92.8 0.7 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGE08112.1 - 2e-14 54.0 1.4 6.7e-14 52.3 1.4 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EGE08112.1 - 0.00027 21.0 0.0 0.0011 19.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 EGE08112.1 - 0.0016 18.0 0.0 0.0032 17.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGE08112.1 - 0.0025 17.3 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EGE08112.1 - 0.0039 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_18 PF00704.28 EGE08114.1 - 7.2e-82 275.6 7.7 8.4e-82 275.4 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AvrE_T3Es PF11725.8 EGE08114.1 - 0.13 9.5 0.1 0.17 9.1 0.1 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) AA_permease PF00324.21 EGE08116.1 - 6.9e-108 361.3 38.3 8.5e-108 361.0 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE08116.1 - 9.7e-16 57.6 42.6 1.5e-15 57.0 42.4 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 EGE08116.1 - 0.0077 16.5 2.3 0.0077 16.5 2.3 3.8 4 1 1 5 5 5 1 Domain of unknown function (DUF1772) RRM_1 PF00076.22 EGE08117.1 - 1.1e-59 198.2 0.0 1.7e-18 66.2 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGE08117.1 - 8.4e-07 29.4 5.3 2.5 8.3 0.0 5.8 5 3 3 8 8 8 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 EGE08117.1 - 0.00015 21.6 0.6 2.5 7.9 0.0 3.6 2 2 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EGE08117.1 - 0.00029 20.9 0.0 4.1 7.6 0.0 3.9 3 0 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EGE08117.1 - 0.0032 17.1 0.0 1.6 8.3 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EGE08117.1 - 0.015 15.4 2.0 0.79 9.8 0.1 4.3 4 1 0 4 4 4 0 Limkain b1 NosL PF05573.12 EGE08117.1 - 0.051 13.9 0.1 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 NosL Rad10 PF03834.14 EGE08118.1 - 5.8e-49 164.9 0.0 8e-49 164.4 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EGE08118.1 - 0.0041 17.7 0.0 0.0085 16.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EGE08118.1 - 0.037 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 EGE08118.1 - 0.04 13.8 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans_2 PF11951.8 EGE08119.1 - 3.3e-16 59.1 0.0 2.1e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EGE08120.1 - 2e-14 53.3 1.1 1.4e-13 50.5 1.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE08120.1 - 1.2e-06 28.5 13.8 2.2e-06 27.7 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YCII PF03795.14 EGE08121.1 - 2.6e-05 24.5 0.0 3.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain AMP-binding PF00501.28 EGE08122.1 - 2.4e-88 296.6 0.0 2.8e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE08122.1 - 1.3e-12 48.5 0.1 2.9e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGE08122.1 - 1.9e-05 23.8 0.0 0.00034 19.6 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EGE08122.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain G-patch PF01585.23 EGE08124.1 - 6.6e-12 45.1 1.2 1.3e-11 44.2 1.2 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EGE08124.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mac PF12464.8 EGE08124.1 - 0.11 12.7 1.7 0.26 11.6 0.7 2.1 2 0 0 2 2 2 0 Maltose acetyltransferase UQ_con PF00179.26 EGE08125.1 - 8.9e-47 158.3 0.0 1e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE08125.1 - 1.3e-05 24.9 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGE08125.1 - 0.21 11.9 0.9 0.43 10.9 0.8 1.6 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 EGE08126.1 - 4.5e-32 112.1 0.0 5.6e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGE08126.1 - 2.6e-16 59.6 0.0 1.3e-14 54.1 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGE08126.1 - 2.3e-12 47.2 0.0 6.2e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 EGE08126.1 - 0.001 18.2 0.1 0.0041 16.3 0.1 1.9 1 1 0 1 1 1 1 NAD synthase DUF3700 PF12481.8 EGE08126.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein QueC PF06508.13 EGE08126.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.22 EGE08127.1 - 1.5e-47 162.3 1.8 1.9e-47 162.0 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic porin DnaJ PF00226.31 EGE08128.1 - 1.5e-23 82.6 0.3 2.8e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 EGE08129.1 - 7e-44 150.0 0.0 8.7e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 EGE08129.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase RNA_polI_A34 PF08208.11 EGE08129.1 - 0.12 12.5 8.1 0.2 11.7 8.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Casc1 PF12366.8 EGE08129.1 - 0.2 11.1 1.5 0.35 10.3 1.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 PGA2 PF07543.12 EGE08129.1 - 0.41 10.6 7.5 0.93 9.5 7.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 EGE08129.1 - 0.55 8.5 6.1 0.76 8.0 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGE08129.1 - 1.4 9.4 6.4 2.9 8.3 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 EGE08130.1 - 3.3e-71 239.8 0.0 1.1e-70 238.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08130.1 - 7.1e-51 173.0 0.0 1.7e-50 171.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE08130.1 - 0.0037 16.1 0.0 0.0076 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGE08130.1 - 0.14 11.5 0.0 0.76 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like GerD PF17898.1 EGE08130.1 - 0.16 11.9 1.1 0.41 10.6 1.1 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Mur_ligase_M PF08245.12 EGE08131.1 - 1.3e-06 28.6 0.1 3.4e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Mur ligase middle domain DUF3120 PF11318.8 EGE08131.1 - 0.047 14.0 0.1 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Mur_ligase_C PF02875.21 EGE08131.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DUF5582 PF17819.1 EGE08132.1 - 0.15 12.5 1.3 0.33 11.4 1.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5582) PRK PF00485.18 EGE08133.1 - 0.00025 20.9 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGE08133.1 - 0.00055 20.5 0.1 0.023 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGE08133.1 - 0.0024 17.1 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 EGE08133.1 - 0.0029 17.8 0.3 0.41 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGE08133.1 - 0.0046 17.4 0.0 0.0073 16.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE08133.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 EGE08133.1 - 0.022 15.2 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EGE08133.1 - 0.078 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 MeaB PF03308.16 EGE08133.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 EGE08133.1 - 0.11 12.1 0.0 4.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_19 PF13245.6 EGE08133.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGE08133.1 - 0.16 11.3 0.4 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 EGE08133.1 - 0.17 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribonuc_red_lgC PF02867.15 EGE08135.1 - 1.1e-186 621.4 0.0 1.6e-186 621.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGE08135.1 - 8.2e-26 89.8 0.0 1.8e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGE08135.1 - 1.6e-16 60.6 0.1 5.7e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain MFS_1 PF07690.16 EGE08136.1 - 1.1e-09 37.7 28.7 1.1e-09 37.7 28.7 4.0 2 2 1 3 3 3 2 Major Facilitator Superfamily Chloroa_b-bind PF00504.21 EGE08136.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.5 3 0 0 3 3 3 0 Chlorophyll A-B binding protein DPBB_1 PF03330.18 EGE08138.1 - 0.0019 18.4 0.0 0.0055 16.9 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase DUF2749 PF10907.8 EGE08138.1 - 0.16 12.1 0.2 0.36 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) DUF1604 PF07713.13 EGE08140.1 - 0.074 12.9 0.9 0.11 12.3 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) Med5 PF08689.10 EGE08143.1 - 4e-143 478.6 0.0 9.6e-142 474.1 0.0 2.5 1 1 0 1 1 1 1 Mediator complex subunit Med5 GHMP_kinases_N PF00288.26 EGE08144.1 - 1.9e-11 44.0 0.1 4.4e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGE08144.1 - 5.6e-05 23.4 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal RasGEF PF00617.19 EGE08146.1 - 7.9e-52 176.0 0.7 1.5e-51 175.1 0.7 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGE08146.1 - 2.7e-14 53.3 0.0 8.8e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EGE08146.1 - 9.4e-07 28.6 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGE08146.1 - 3.2e-05 23.5 0.0 7.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Lipoprotein_20 PF13942.6 EGE08146.1 - 2.2 8.1 4.2 9.8 6.1 0.0 3.0 3 0 0 3 3 3 0 YfhG lipoprotein HATPase_c_3 PF13589.6 EGE08147.1 - 2.7e-17 62.9 0.0 4.7e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EGE08147.1 - 1.5e-10 41.0 0.0 1.1e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EGE08147.1 - 1.7e-05 25.3 0.1 3.6e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SLATT_fungal PF18142.1 EGE08149.1 - 1.3e-34 118.7 0.0 1.8e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Vicilin_N PF04702.12 EGE08149.1 - 0.085 12.7 3.6 0.13 12.1 3.6 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Ninjurin PF04923.12 EGE08149.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Ninjurin Zn_clus PF00172.18 EGE08150.1 - 2.3e-07 30.8 14.1 2.3e-07 30.8 14.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE08150.1 - 0.0016 17.4 0.4 0.0016 17.4 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MBOAT_2 PF13813.6 EGE08151.1 - 2e-14 53.6 5.3 2e-14 53.6 5.3 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RTA1 PF04479.13 EGE08153.1 - 4.3e-67 225.7 15.5 4.3e-67 225.7 15.5 1.3 2 0 0 2 2 2 1 RTA1 like protein LHC PF00556.20 EGE08153.1 - 2.4 8.5 8.7 1 9.7 2.0 2.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DENN PF02141.21 EGE08154.1 - 3.2e-55 187.0 0.1 6.4e-55 186.0 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EGE08154.1 - 2.7e-15 56.8 0.3 1.7e-14 54.3 0.0 2.6 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 EGE08154.1 - 3.7e-14 52.4 0.7 8.4e-14 51.3 0.7 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 EGE08154.1 - 1.7e-06 28.3 4.6 3.7e-06 27.1 4.6 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EGE08154.1 - 0.0057 16.5 5.8 0.012 15.5 5.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGE08154.1 - 0.16 12.1 6.0 0.38 10.9 6.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 EGE08154.1 - 2.7 7.9 8.4 2 8.4 6.2 2.0 1 1 1 2 2 2 0 PHD-finger DUF974 PF06159.13 EGE08155.1 - 1.8e-62 211.4 0.0 2.2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) zf-ANAPC11 PF12861.7 EGE08156.1 - 1.2e-06 28.5 6.2 6.6e-06 26.1 1.9 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGE08156.1 - 1.3e-06 28.6 6.2 1.3e-06 28.6 6.2 2.2 2 1 0 2 2 2 1 Ring finger domain SWIM PF04434.17 EGE08156.1 - 8.8e-06 25.3 0.6 1.6e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 EGE08156.1 - 0.0014 18.8 7.9 0.0061 16.7 5.2 2.4 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING_4 PF14570.6 EGE08156.1 - 0.005 16.6 6.4 0.011 15.5 6.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.29 EGE08156.1 - 0.009 15.9 7.1 0.022 14.7 7.1 1.7 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.7 EGE08156.1 - 0.024 14.7 8.7 0.054 13.6 8.7 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 EGE08156.1 - 0.52 10.3 6.6 0.32 10.9 2.7 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.6 EGE08156.1 - 0.82 9.6 7.8 0.21 11.5 4.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE08156.1 - 1.1 9.6 11.2 0.12 12.7 5.9 2.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain SCRL PF06876.12 EGE08156.1 - 2.4 8.4 8.7 0.64 10.2 1.3 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-RING_UBOX PF13445.6 EGE08156.1 - 5.9 7.0 9.2 0.27 11.3 3.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger CENP-N PF05238.13 EGE08157.1 - 8.1e-114 381.1 6.4 1.4e-113 380.4 6.4 1.4 1 1 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 EGE08159.1 - 4.2e-13 49.2 12.1 7.2e-13 48.4 12.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGE08159.1 - 2.1e-05 24.5 10.9 3.6e-05 23.8 10.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 EGE08159.1 - 0.098 13.0 0.5 0.39 11.1 0.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF4094 PF13334.6 EGE08159.1 - 1.3 9.5 5.2 0.27 11.7 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TFIIA PF03153.13 EGE08159.1 - 1.6 8.7 30.0 2.7 7.9 30.0 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOGA PF11365.8 EGE08159.1 - 1.6 9.9 8.5 0.28 12.3 3.7 2.1 2 0 0 2 2 2 0 Protein SOGA CCDC106 PF15794.5 EGE08159.1 - 2.2 8.0 16.9 0.83 9.3 1.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Nucleo_P87 PF07267.11 EGE08159.1 - 9.6 4.9 13.6 13 4.5 13.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BRO1 PF03097.18 EGE08160.1 - 3.7e-121 404.6 0.2 1.4e-119 399.4 0.0 2.6 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGE08160.1 - 2.8e-88 296.1 11.0 6.6e-88 294.8 11.0 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Cellulase-like PF12876.7 EGE08160.1 - 0.0094 15.3 0.6 0.098 12.0 0.1 2.1 2 0 0 2 2 2 1 Sugar-binding cellulase-like GAS PF13851.6 EGE08160.1 - 2.3 7.5 11.3 0.33 10.3 4.7 2.8 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Mito_carr PF00153.27 EGE08161.1 - 5.9e-40 135.1 5.7 9.6e-16 57.5 0.4 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EBP50_C PF09007.11 EGE08162.1 - 1.4 9.9 8.8 2.8 8.9 8.8 1.6 1 1 0 1 1 1 0 EBP50, C-terminal CDC45 PF02724.14 EGE08162.1 - 1.5 7.0 9.0 1.6 6.9 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Thiolase_N PF00108.23 EGE08163.1 - 1.4e-14 54.1 0.1 2.2e-13 50.2 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGE08163.1 - 9e-12 44.7 2.9 6.7e-11 41.9 0.0 2.8 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EGE08163.1 - 1.3e-07 31.3 0.1 1e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EGE08163.1 - 0.003 17.2 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EGE08163.1 - 0.013 14.2 0.4 0.042 12.6 0.1 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) SMN PF06003.12 EGE08164.1 - 1e-08 34.8 1.1 2.4e-07 30.3 0.1 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF2254 PF10011.9 EGE08164.1 - 0.19 10.5 0.5 0.23 10.2 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Cytadhesin_P30 PF07271.11 EGE08164.1 - 2 7.9 11.2 0.15 11.6 1.5 2.0 1 1 1 2 2 2 0 Cytadhesin P30/P32 RRM_1 PF00076.22 EGE08165.1 - 5e-15 55.1 0.0 1.4e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGE08165.1 - 0.023 14.8 0.0 0.12 12.5 0.0 2.2 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EGE08165.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TRAM_LAG1_CLN8 PF03798.16 EGE08166.1 - 1.4e-39 135.9 22.8 1.4e-39 135.9 22.8 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EGE08166.1 - 1.9e-13 49.9 0.1 1.9e-13 49.9 0.1 2.3 2 0 0 2 2 2 1 TRAM1-like protein AA_permease_2 PF13520.6 EGE08168.1 - 4.4e-49 167.5 49.2 5.7e-49 167.1 49.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE08168.1 - 7e-26 90.8 44.4 4.7e-25 88.1 44.4 1.9 1 1 0 1 1 1 1 Amino acid permease Neuregulin PF02158.15 EGE08170.1 - 0.0011 18.5 3.1 0.0016 17.9 3.1 1.2 1 0 0 1 1 1 1 Neuregulin intracellular region Drc1-Sld2 PF11719.8 EGE08170.1 - 0.002 17.7 5.2 0.002 17.7 5.2 1.5 2 0 0 2 2 2 1 DNA replication and checkpoint protein E3_UbLigase_EDD PF11547.8 EGE08170.1 - 0.0093 15.6 1.1 0.026 14.2 1.1 1.7 1 0 0 1 1 1 1 E3 ubiquitin ligase EDD Ebp2 PF05890.12 EGE08171.1 - 3.4e-94 315.4 14.7 3.4e-94 315.4 14.7 2.2 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HSBP1 PF06825.12 EGE08172.1 - 2.5e-20 72.0 1.8 3.1e-20 71.8 1.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 EGE08172.1 - 0.00012 22.4 1.6 0.00014 22.1 1.6 1.1 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 EGE08172.1 - 0.00018 21.3 0.5 0.0014 18.4 0.5 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 EGE08172.1 - 0.00099 19.5 1.0 0.0013 19.2 1.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EGE08172.1 - 0.0023 17.9 0.5 0.0026 17.8 0.5 1.1 1 0 0 1 1 1 1 Laminin Domain II DUF3235 PF11574.8 EGE08172.1 - 0.0032 18.3 0.4 0.0039 18.0 0.4 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3235) Baculo_PEP_C PF04513.12 EGE08172.1 - 0.0075 16.3 0.6 0.009 16.1 0.6 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus BORCS6 PF10157.9 EGE08172.1 - 0.024 14.9 0.3 0.026 14.7 0.3 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF3450 PF11932.8 EGE08172.1 - 0.041 13.2 2.5 0.048 13.0 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 EGE08172.1 - 0.079 12.5 0.8 0.082 12.5 0.8 1.1 1 0 0 1 1 1 0 fzo-like conserved region Thioredoxin PF00085.20 EGE08173.1 - 5.9e-56 186.8 0.0 4.2e-28 97.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGE08173.1 - 7.3e-24 84.5 0.5 2.1e-23 83.0 0.3 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EGE08173.1 - 2.3e-14 53.7 0.0 2.9e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGE08173.1 - 9.8e-13 48.1 0.0 1.6e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGE08173.1 - 4.9e-08 33.1 0.0 0.00074 19.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EGE08173.1 - 1.9e-06 28.1 0.0 0.41 11.0 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EGE08173.1 - 4.2e-06 26.7 0.0 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 EGE08173.1 - 4.1e-05 23.5 0.0 0.066 13.0 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EGE08173.1 - 0.00047 19.9 0.1 0.25 11.1 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EGE08173.1 - 0.0016 18.4 0.0 0.62 9.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 EGE08173.1 - 0.0075 16.2 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EGE08173.1 - 0.013 15.7 0.0 5.8 7.2 0.1 2.8 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_4 PF13462.6 EGE08173.1 - 0.068 13.3 1.8 66 3.6 0.0 3.8 3 1 1 4 4 4 0 Thioredoxin YjbR PF04237.13 EGE08174.1 - 0.0035 17.9 0.1 0.045 14.3 0.0 2.1 1 1 1 2 2 2 1 YjbR Abhydrolase_6 PF12697.7 EGE08176.1 - 2.9e-14 54.2 0.2 3.7e-14 53.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE08176.1 - 6.8e-12 45.6 0.2 2.8e-10 40.3 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE08176.1 - 4.8e-11 42.4 0.0 7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGE08176.1 - 0.0011 19.1 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGE08176.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S28 PF05577.12 EGE08176.1 - 0.027 13.3 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 F-box-like PF12937.7 EGE08177.1 - 0.00017 21.4 1.1 0.00046 20.0 1.1 1.8 1 0 0 1 1 1 1 F-box-like NAD_binding_2 PF03446.15 EGE08178.1 - 1.2e-33 116.5 0.1 3.1e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EGE08178.1 - 2e-12 47.5 0.1 9.7e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGE08178.1 - 6.4e-12 45.7 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EGE08178.1 - 3.4e-11 43.4 0.9 5.8e-11 42.7 0.9 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 EGE08178.1 - 0.00029 20.4 0.4 0.00082 19.0 0.1 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EGE08178.1 - 0.0067 16.7 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EGE08178.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EGE08178.1 - 0.0093 15.9 0.9 5.2 7.1 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase TrkA_N PF02254.18 EGE08178.1 - 0.023 15.0 0.0 0.07 13.4 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EGE08178.1 - 0.088 13.6 0.0 0.22 12.4 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_72 PF03198.14 EGE08180.1 - 1.6e-130 435.0 1.0 1.9e-130 434.7 1.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EGE08180.1 - 1.9e-23 82.9 0.5 6.2e-23 81.3 0.5 1.9 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EGE08180.1 - 0.017 14.3 0.1 0.092 11.8 0.1 2.2 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 EGE08180.1 - 0.068 12.6 0.4 12 5.2 0.1 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) PBP1_TM PF14812.6 EGE08181.1 - 0.00093 19.5 6.8 0.022 15.1 0.5 2.4 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Orf78 PF06024.12 EGE08181.1 - 0.0016 18.7 5.0 0.091 13.1 0.0 2.2 2 0 0 2 2 2 1 Orf78 (ac78) Ferlin_C PF16165.5 EGE08181.1 - 0.0053 16.7 10.7 0.0054 16.7 0.7 2.2 2 0 0 2 2 2 1 Ferlin C-terminus ETRAMP PF09716.10 EGE08181.1 - 0.012 15.6 1.1 0.012 15.6 1.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CPSF100_C PF13299.6 EGE08181.1 - 0.013 15.7 11.2 0.39 10.9 1.0 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BRF1 PF07741.13 EGE08181.1 - 0.017 15.4 15.3 0.15 12.4 0.9 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SET PF00856.28 EGE08181.1 - 0.036 14.5 2.8 0.91 9.9 2.8 2.1 1 1 0 1 1 1 0 SET domain RNA_pol_Rpc4 PF05132.14 EGE08181.1 - 0.045 14.2 0.1 0.045 14.2 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 BUD22 PF09073.10 EGE08181.1 - 0.075 12.4 19.8 0.13 11.6 9.1 2.1 2 0 0 2 2 2 0 BUD22 Peroxin-13_N PF04088.13 EGE08181.1 - 0.084 13.2 7.4 2.6 8.3 0.3 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SARAF PF06682.12 EGE08181.1 - 0.086 12.5 6.6 0.68 9.5 6.6 2.0 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 EGE08181.1 - 0.093 12.3 20.2 0.028 14.0 3.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GEN1_C PF18380.1 EGE08181.1 - 0.094 13.6 10.4 0.47 11.4 0.8 2.2 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Peptidase_S49_N PF08496.10 EGE08181.1 - 0.12 12.4 14.1 0.65 10.0 4.8 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1676 PF07898.13 EGE08181.1 - 0.14 12.1 6.6 0.077 13.0 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF229 PF02995.17 EGE08181.1 - 0.16 10.6 3.0 0.2 10.2 2.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF229) DUF1385 PF07136.11 EGE08181.1 - 0.19 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) AgrB PF04647.15 EGE08181.1 - 0.2 11.0 1.0 0.37 10.1 1.0 1.4 1 0 0 1 1 1 0 Accessory gene regulator B DUF4647 PF15504.6 EGE08181.1 - 0.26 10.3 14.1 0.12 11.5 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) TMEM171 PF15471.6 EGE08181.1 - 0.26 10.2 2.0 0.37 9.7 2.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 SID-1_RNA_chan PF13965.6 EGE08181.1 - 0.27 9.6 0.7 0.32 9.4 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NST1 PF13945.6 EGE08181.1 - 0.29 11.2 22.2 1.1 9.3 8.1 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF2615 PF11027.8 EGE08181.1 - 0.32 11.1 0.1 0.32 11.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Spt20 PF12090.8 EGE08181.1 - 0.35 10.5 21.2 0.36 10.4 13.8 2.1 2 0 0 2 2 2 0 Spt20 family DUF5345 PF17280.2 EGE08181.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) XAP5 PF04921.14 EGE08181.1 - 0.51 10.1 18.5 2.1 8.1 7.0 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator RR_TM4-6 PF06459.12 EGE08181.1 - 0.71 9.7 17.6 0.52 10.1 3.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.6 EGE08181.1 - 0.71 10.2 8.8 7.4 6.9 0.3 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2052 PF09747.9 EGE08181.1 - 0.75 9.9 18.3 1.2 9.2 2.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Suf PF05843.14 EGE08181.1 - 0.85 9.6 11.4 1.2 9.1 11.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) U3_snoRNA_assoc PF08297.11 EGE08181.1 - 0.85 10.4 22.5 2.7 8.8 5.7 2.4 2 0 0 2 2 2 0 U3 snoRNA associated DUF702 PF05142.12 EGE08181.1 - 0.87 10.0 10.7 3.7 8.0 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF3807 PF12720.7 EGE08181.1 - 0.93 9.7 24.1 0.12 12.6 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF3464 PF11947.8 EGE08181.1 - 1.1 9.0 12.2 0.76 9.5 3.1 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 NPR3 PF03666.13 EGE08181.1 - 1.1 8.0 10.8 2.9 6.6 3.9 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Folate_carrier PF01770.18 EGE08181.1 - 1.2 7.8 10.8 0.018 13.8 2.1 1.8 1 1 1 2 2 2 0 Reduced folate carrier CAC1F_C PF16885.5 EGE08181.1 - 1.2 8.7 10.0 1.6 8.4 10.0 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term AP3D1 PF06375.11 EGE08181.1 - 1.3 9.2 24.5 0.26 11.5 5.0 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 MPP6 PF10175.9 EGE08181.1 - 1.4 9.4 19.4 1.1 9.7 8.4 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Cnd1_N PF12922.7 EGE08181.1 - 1.5 8.7 8.7 4.7 7.0 0.6 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term RNA_polI_A34 PF08208.11 EGE08181.1 - 1.6 8.7 27.9 0.16 12.0 2.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Rxt3 PF08642.10 EGE08181.1 - 2.3 9.0 9.3 3.2 8.5 2.4 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Spt5_N PF11942.8 EGE08181.1 - 2.5 9.2 18.0 1.7 9.7 7.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TMEM51 PF15345.6 EGE08181.1 - 3.2 7.5 10.6 20 4.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Otopetrin PF03189.13 EGE08181.1 - 4.1 6.1 4.4 11 4.7 0.1 1.9 2 0 0 2 2 2 0 Otopetrin EMC3_TMCO1 PF01956.16 EGE08181.1 - 5.2 6.8 11.6 3.8 7.2 3.6 2.1 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Ndc1_Nup PF09531.10 EGE08181.1 - 5.4 5.6 8.1 6.4 5.3 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop53 PF07767.11 EGE08181.1 - 5.8 6.2 29.0 1 8.6 12.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Sec62 PF03839.16 EGE08181.1 - 6.4 6.2 14.5 2.8 7.4 2.5 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 DUF755 PF05501.11 EGE08181.1 - 6.7 7.0 27.8 7.2 6.9 9.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PigN PF04987.14 EGE08181.1 - 6.8 5.4 5.2 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) DUF3381 PF11861.8 EGE08181.1 - 7.2 6.4 30.1 2.4 8.0 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF1764 PF08576.10 EGE08181.1 - 8.3 7.4 20.7 0.31 12.0 2.7 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) GREB1 PF15782.5 EGE08181.1 - 8.6 3.3 10.9 9.6 3.2 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4484 PF14831.6 EGE08181.1 - 8.7 6.3 11.5 4.7 7.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Med19 PF10278.9 EGE08181.1 - 8.9 6.2 22.4 0.25 11.3 4.9 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PRP38_assoc PF12871.7 EGE08181.1 - 9 7.0 18.5 6.2 7.5 10.0 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Cnd2 PF05786.14 EGE08181.1 - 9.7 4.7 19.6 0.68 8.5 6.6 2.0 2 0 0 2 2 2 0 Condensin complex subunit 2 BAR_2 PF10455.9 EGE08183.1 - 3.1e-46 157.8 0.7 7.7e-44 149.9 0.7 2.2 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EGE08183.1 - 2.8e-14 53.3 4.2 1.7e-13 50.8 4.2 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGE08183.1 - 0.012 15.4 0.7 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 BAR domain of APPL family ApoLp-III PF07464.11 EGE08183.1 - 0.014 15.5 2.2 0.6 10.2 0.1 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TetR_C_24 PF17932.1 EGE08183.1 - 0.057 13.7 0.2 0.19 12.0 0.1 1.9 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4972 PF16342.5 EGE08183.1 - 0.11 12.2 0.2 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Aminotran_3 PF00202.21 EGE08184.1 - 5.2e-82 275.7 0.0 6.3e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF3810 PF12725.7 EGE08185.1 - 0.059 12.7 0.1 0.059 12.7 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Dabb PF07876.12 EGE08187.1 - 5.5e-16 59.0 0.0 5.9e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4123 PF13503.6 EGE08187.1 - 0.16 12.4 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) ATP_synt_H PF05493.13 EGE08188.1 - 3.5e-20 72.2 1.0 3.9e-20 72.1 1.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.11 EGE08188.1 - 0.022 14.2 0.3 0.027 14.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YfhO PF09586.10 EGE08188.1 - 0.13 10.5 0.1 0.13 10.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Arv1 PF04161.13 EGE08189.1 - 2.6e-61 207.4 0.0 7.8e-52 176.5 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family DUF1180 PF06679.12 EGE08189.1 - 3 8.2 5.1 7.3 7.0 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TPR_12 PF13424.6 EGE08190.1 - 1.1e-35 121.7 10.6 1.8e-11 44.1 1.2 7.5 2 1 7 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGE08190.1 - 3.2e-27 93.6 6.0 0.00021 21.1 0.1 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat Helo_like_N PF17111.5 EGE08190.1 - 1.8e-09 37.3 0.4 8.1e-09 35.1 0.4 2.1 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins TPR_MalT PF17874.1 EGE08190.1 - 7e-08 32.2 1.3 0.039 13.3 2.4 3.3 2 1 2 4 4 4 3 MalT-like TPR region TPR_19 PF14559.6 EGE08190.1 - 1.2e-06 28.9 7.2 0.72 10.4 0.1 5.6 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08190.1 - 1.6e-05 24.7 5.2 16 5.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08190.1 - 3.1e-05 24.5 5.6 0.15 12.7 1.2 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE08190.1 - 0.00021 21.0 0.6 4.8 7.2 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EGE08190.1 - 0.00024 21.4 14.3 0.14 12.9 0.5 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3427 PF11907.8 EGE08190.1 - 0.0012 18.2 0.2 0.0024 17.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3427) NB-ARC PF00931.22 EGE08190.1 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EGE08190.1 - 0.0019 18.2 0.0 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EGE08190.1 - 0.0062 16.5 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TPR_14 PF13428.6 EGE08190.1 - 0.0066 17.2 12.8 6 8.0 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat SesA PF17107.5 EGE08190.1 - 0.019 15.1 0.1 0.14 12.3 0.0 2.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_7 PF13176.6 EGE08190.1 - 0.021 14.8 6.4 34 4.8 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGE08190.1 - 0.03 14.5 1.5 19 5.8 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Arf PF00025.21 EGE08190.1 - 0.046 13.2 0.0 0.29 10.6 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 EGE08190.1 - 0.063 13.5 0.0 0.29 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain FlgN PF05130.12 EGE08190.1 - 0.068 13.7 0.0 0.068 13.7 0.0 2.8 3 0 0 3 3 3 0 FlgN protein AAA_24 PF13479.6 EGE08190.1 - 0.13 11.9 0.0 0.43 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 EGE08191.1 - 2e-36 125.8 0.0 2.4e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE08191.1 - 7.9e-17 61.6 0.0 9.1e-13 48.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE08191.1 - 9.6e-08 31.6 0.0 6.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGE08191.1 - 1.4e-06 27.7 0.0 2.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGE08191.1 - 9.2e-06 25.8 0.0 0.013 15.7 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGE08191.1 - 3.6e-05 23.8 0.3 0.053 13.5 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGE08191.1 - 0.00062 18.6 0.0 0.17 10.6 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 EGE08191.1 - 0.00093 18.2 0.1 6.6 5.4 0.0 3.1 2 1 0 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EGE08191.1 - 0.0013 17.8 0.0 1.6 7.7 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein TrkA_N PF02254.18 EGE08191.1 - 0.0014 18.9 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain DUF1188 PF06690.11 EGE08191.1 - 0.0034 17.0 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) DAO PF01266.24 EGE08191.1 - 0.0043 16.7 0.1 3.5 7.1 0.1 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGE08191.1 - 0.0067 15.7 0.0 0.48 9.6 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EGE08191.1 - 0.055 13.9 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAT PF04768.13 EGE08192.1 - 3.7e-51 173.2 0.0 8e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF2781 PF10914.8 EGE08193.1 - 1.9e-40 138.7 11.7 2.1e-40 138.5 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) SLAC1 PF03595.17 EGE08193.1 - 0.0047 16.2 3.1 0.0055 16.0 3.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Nucleoporin_N PF08801.11 EGE08194.1 - 4.7e-89 299.1 0.3 6.8e-89 298.6 0.3 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EGE08194.1 - 3.8e-44 151.4 1.3 2.4e-43 148.8 0.5 1.9 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Fungal_lectin PF07938.12 EGE08194.1 - 0.16 11.3 0.0 0.44 9.9 0.0 1.6 1 1 0 1 1 1 0 Fungal fucose-specific lectin YqeY PF09424.10 EGE08195.1 - 9e-20 71.2 7.6 9.9e-20 71.1 6.7 1.4 1 1 1 2 2 2 1 Yqey-like protein Ino80_Iec3 PF14612.6 EGE08195.1 - 0.0054 17.4 0.3 0.0069 17.1 0.3 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Rot1 PF10681.9 EGE08196.1 - 1.7e-92 308.7 0.0 1.9e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.20 EGE08197.1 - 2.8e-33 115.3 0.0 6.8e-33 114.1 0.0 1.5 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 EGE08198.1 - 2.8e-13 49.3 0.2 3.4e-13 49.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGE08198.1 - 0.001 18.7 0.1 0.0016 18.0 0.1 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 EGE08199.1 - 6.1e-29 101.0 0.1 1.6e-27 96.4 0.1 3.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EGE08199.1 - 6.1e-08 32.5 0.8 1.5e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EGE08199.1 - 0.0028 18.0 0.0 0.029 14.7 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EGE08199.1 - 0.017 15.6 0.0 0.24 11.9 0.0 3.2 2 0 0 2 2 2 0 HEAT-like repeat GAT PF03127.14 EGE08199.1 - 0.033 14.5 0.0 2.5 8.5 0.0 3.0 2 0 0 2 2 2 0 GAT domain HEAT PF02985.22 EGE08199.1 - 0.047 13.9 0.0 24 5.6 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat ICAT PF06384.11 EGE08199.1 - 5.7 7.3 7.8 1.9 8.8 2.0 2.7 3 0 0 3 3 3 0 Beta-catenin-interacting protein ICAT Glyco_transf_90 PF05686.12 EGE08200.1 - 7.9e-13 48.1 0.3 6.3e-12 45.1 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 90 Fungal_trans PF04082.18 EGE08202.1 - 3.2e-63 213.3 1.2 5.5e-63 212.5 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EGE08202.1 - 0.00035 20.9 14.7 0.0053 17.1 3.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EGE08202.1 - 0.01 16.1 1.6 0.036 14.4 1.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EGE08202.1 - 6.5 7.9 19.9 0.34 11.8 3.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE08202.1 - 9.2 6.9 10.4 2 9.0 2.7 2.8 2 0 0 2 2 2 0 Zinc-finger double domain EF-hand_7 PF13499.6 EGE08203.1 - 3.6e-13 49.8 0.2 9.1e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGE08203.1 - 4.8e-11 42.8 0.0 3.7e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EGE08203.1 - 4.3e-10 38.7 0.1 0.01 15.7 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGE08203.1 - 1.2e-09 37.0 0.0 0.017 14.6 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGE08203.1 - 1e-06 28.4 0.1 3.7e-05 23.5 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 EGE08203.1 - 0.093 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_14 PF17959.1 EGE08203.1 - 0.097 13.0 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain DUF4637 PF15470.6 EGE08204.1 - 0.039 13.7 3.5 0.093 12.5 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) YABBY PF04690.13 EGE08204.1 - 0.077 13.6 0.7 8.2 7.0 0.4 2.5 2 1 0 2 2 2 0 YABBY protein CDC45 PF02724.14 EGE08204.1 - 0.15 10.3 3.3 0.2 9.9 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGE08204.1 - 0.3 10.4 9.2 0.49 9.7 9.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PI3K_1B_p101 PF10486.9 EGE08204.1 - 0.34 8.7 4.9 0.49 8.1 4.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpc4 PF05132.14 EGE08204.1 - 1.1 9.7 5.9 0.11 12.9 0.8 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nucleo_P87 PF07267.11 EGE08204.1 - 1.7 7.4 4.9 2.1 7.1 4.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.13 EGE08204.1 - 3.9 6.4 11.3 5.4 5.9 11.3 1.1 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 EGE08204.1 - 9.1 4.2 9.2 12 3.9 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_M3 PF01432.20 EGE08205.1 - 6.6e-130 434.4 0.3 2.3e-78 264.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M3 Cyt-b5 PF00173.28 EGE08206.1 - 1.8e-17 63.3 0.1 4.6e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EGE08206.1 - 1.2e-10 41.7 19.0 5.2e-07 29.8 5.3 2.5 2 1 1 3 3 3 2 Fatty acid desaturase DUF1189 PF06691.11 EGE08206.1 - 0.013 15.0 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Eaf7 PF07904.13 EGE08206.1 - 1.5 9.2 3.7 2.8 8.3 0.2 2.2 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 FA_hydroxylase PF04116.13 EGE08206.1 - 4.8 7.5 8.8 3.3 8.1 2.0 2.3 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Rad51 PF08423.11 EGE08208.1 - 9.5e-13 48.0 0.0 6e-12 45.4 0.0 2.1 2 1 0 2 2 2 1 Rad51 ATPase PF06745.13 EGE08208.1 - 1.7e-05 24.3 0.1 0.00012 21.5 0.0 2.2 2 1 0 2 2 2 1 KaiC RecA PF00154.21 EGE08208.1 - 6.4e-05 22.5 0.0 0.00014 21.5 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein PhoH PF02562.16 EGE08208.1 - 0.00042 19.8 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 EGE08208.1 - 0.0013 18.4 1.0 0.0052 16.4 0.1 2.5 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGE08208.1 - 0.0029 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.23 EGE08208.1 - 0.0059 16.7 0.0 0.027 14.5 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EGE08208.1 - 0.0083 16.5 1.0 0.019 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EGE08208.1 - 0.011 15.7 0.1 0.023 14.6 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGE08208.1 - 0.022 15.3 0.5 0.056 14.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter RNA12 PF10443.9 EGE08208.1 - 0.042 12.6 1.3 0.087 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA12 protein Zot PF05707.12 EGE08208.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DnaB_C PF03796.15 EGE08208.1 - 0.082 12.2 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Amidase PF01425.21 EGE08209.1 - 4.4e-69 233.6 0.0 5.4e-68 230.0 0.0 2.0 1 1 0 1 1 1 1 Amidase MOSC PF03473.17 EGE08210.1 - 1.4e-19 70.4 0.0 2.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGE08210.1 - 1.1e-08 35.0 0.0 5.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Dicty_REP PF05086.12 EGE08211.1 - 0.009 14.1 3.3 0.011 13.8 3.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein SelP_N PF04592.14 EGE08211.1 - 0.83 9.0 44.9 1.2 8.5 10.1 2.4 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NPR3 PF03666.13 EGE08212.1 - 0.0035 16.2 3.7 0.0039 16.0 3.7 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 EGE08212.1 - 1.3 8.7 7.2 1.6 8.5 7.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EGE08212.1 - 2.5 6.3 11.8 2.8 6.1 11.8 1.0 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 EGE08213.1 - 2e-05 24.3 0.0 6.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGE08213.1 - 0.0028 17.5 0.1 0.0062 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EGE08213.1 - 0.003 17.4 0.0 0.0079 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 EGE08213.1 - 0.13 12.7 0.6 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 PRANC domain SAP30_Sin3_bdg PF13867.6 EGE08214.1 - 2.3e-09 37.4 0.2 7e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 BRO1 PF03097.18 EGE08215.1 - 1.1e-129 432.7 0.5 1.1e-129 432.7 0.5 1.9 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGE08215.1 - 6.8e-81 271.8 15.4 1.4e-80 270.8 15.4 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2383 PF09537.10 EGE08215.1 - 0.69 10.3 7.2 1.3 9.4 0.5 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF2383) DUF416 PF04222.12 EGE08215.1 - 3.1 7.2 6.9 1.2 8.5 0.1 3.2 4 1 1 5 5 5 0 Protein of unknown function (DUF416) DnaJ_C PF01556.18 EGE08216.1 - 1.1e-36 126.2 0.0 1.5e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGE08216.1 - 2.3e-22 78.9 0.9 6.7e-22 77.4 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGE08216.1 - 1.1e-09 38.5 21.4 1.1e-09 38.5 21.4 1.9 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.19 EGE08216.1 - 0.25 11.4 8.7 0.079 13.0 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EGE08216.1 - 2.7 8.0 19.7 0.18 11.8 5.2 2.9 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein MS_channel PF00924.18 EGE08220.1 - 2e-19 70.0 0.5 4.2e-19 68.9 0.5 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 EGE08220.1 - 0.53 10.8 1.6 0.83 10.1 0.1 2.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 EGE08220.1 - 3.2 7.5 5.3 0.28 10.8 0.2 2.0 2 0 0 2 2 2 0 EF hand TraG_N PF07916.11 EGE08220.1 - 8.7 5.1 8.4 0.11 11.4 0.1 1.9 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Stanniocalcin PF03298.13 EGE08221.1 - 0.00036 19.9 0.0 0.0005 19.4 0.0 1.2 1 0 0 1 1 1 1 Stanniocalcin family Phage_lysozyme PF00959.19 EGE08222.1 - 2.2e-12 47.4 0.0 2.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Phage lysozyme NLPC_P60 PF00877.19 EGE08223.1 - 0.0016 18.4 0.2 0.0025 17.8 0.2 1.3 1 0 0 1 1 1 1 NlpC/P60 family zf-RING_2 PF13639.6 EGE08225.1 - 2e-13 50.4 5.4 3.1e-13 49.8 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGE08225.1 - 2.1e-10 40.1 1.6 3.5e-10 39.4 1.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGE08225.1 - 8.4e-09 35.1 5.0 1.4e-08 34.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE08225.1 - 7.1e-08 32.2 2.1 1.2e-07 31.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGE08225.1 - 1.8e-06 28.2 5.8 5.8e-06 26.5 5.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGE08225.1 - 1.2e-05 25.1 6.7 0.00016 21.4 6.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGE08225.1 - 4e-05 23.5 1.7 6.7e-05 22.8 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGE08225.1 - 7.2e-05 22.6 1.9 0.00014 21.6 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE08225.1 - 0.00013 21.9 4.3 0.00027 20.9 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGE08225.1 - 0.00044 20.2 1.5 0.00088 19.3 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGE08225.1 - 0.014 15.1 2.9 0.027 14.3 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EGE08225.1 - 0.11 12.9 1.1 0.22 11.9 1.1 1.6 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 EGE08225.1 - 0.21 11.3 1.2 0.35 10.5 1.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EGE08225.1 - 0.26 11.2 3.8 0.35 10.8 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EGE08225.1 - 0.78 9.7 2.7 1.6 8.7 2.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EGE08225.1 - 0.95 9.7 5.1 1.9 8.7 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGE08225.1 - 2.5 8.4 6.4 3.7 7.8 3.8 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Mgm101p PF06420.12 EGE08226.1 - 4.9e-87 289.8 0.0 6.8e-87 289.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Macoilin PF09726.9 EGE08226.1 - 0.076 11.6 1.6 0.078 11.5 1.6 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EGE08226.1 - 1.6 7.5 7.2 1.9 7.3 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CHCH PF06747.13 EGE08227.1 - 1.9e-07 31.0 9.4 7.6e-07 29.1 8.1 2.0 2 0 0 2 2 2 1 CHCH domain CX9C PF16860.5 EGE08227.1 - 0.0034 17.4 2.8 0.44 10.6 0.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EGE08227.1 - 0.0092 15.7 3.2 0.031 14.0 0.1 2.1 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGE08227.1 - 0.011 15.7 5.4 0.066 13.2 0.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_N PF09825.9 EGE08228.1 - 1.7e-146 488.1 0.0 6.9e-146 486.2 0.0 1.8 1 1 1 2 2 2 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EGE08228.1 - 6.9e-24 84.2 0.0 1.2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGE08228.1 - 6.3e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain TANGO2 PF05742.12 EGE08229.1 - 1.8e-73 247.7 0.0 2.1e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 T3SchapCesA PF11439.8 EGE08231.1 - 0.032 14.3 0.2 0.047 13.8 0.2 1.2 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA Acetyltransf_2 PF00797.17 EGE08231.1 - 0.12 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase SMBP PF16785.5 EGE08235.1 - 0.012 15.8 1.5 0.015 15.5 1.5 1.1 1 0 0 1 1 1 0 Small metal-binding protein EST1_DNA_bind PF10373.9 EGE08237.1 - 2.3e-07 30.6 0.3 0.00012 21.6 0.1 2.4 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain zf-C2H2 PF00096.26 EGE08238.1 - 2.7e-12 46.4 18.3 0.0059 17.0 0.4 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE08238.1 - 2.7e-12 46.4 22.7 0.002 18.8 0.4 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-Di19 PF05605.12 EGE08238.1 - 1.4e-11 44.5 12.0 0.0002 21.6 1.5 3.6 1 1 1 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EGE08238.1 - 8.2e-11 41.9 12.9 7.9e-05 22.8 0.1 4.9 6 0 0 6 6 5 2 Zinc-finger double-stranded RNA-binding zf_Hakai PF18408.1 EGE08238.1 - 2.9e-10 39.7 7.9 3.4e-05 23.5 0.0 4.0 4 0 0 4 4 4 2 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 EGE08238.1 - 6.1e-10 39.1 19.5 0.0011 19.3 0.3 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-RING_7 PF02591.15 EGE08238.1 - 0.0039 17.3 2.5 3.7 7.8 0.0 3.5 3 0 0 3 3 3 2 C4-type zinc ribbon domain zf-C2H2_2 PF12756.7 EGE08238.1 - 0.013 15.8 5.2 0.32 11.4 1.8 3.3 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 EGE08238.1 - 0.016 15.9 3.3 9.3 6.9 0.2 3.5 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats Spt46 PF17734.1 EGE08238.1 - 0.035 13.9 4.3 2 8.1 0.5 2.5 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 DUF4187 PF13821.6 EGE08238.1 - 0.037 13.8 12.4 7.5 6.4 0.1 5.3 4 2 2 6 6 6 0 Domain of unknown function (DUF4187) DUF4741 PF15897.5 EGE08238.1 - 0.082 12.7 0.4 5.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4741) zf-met PF12874.7 EGE08238.1 - 0.11 12.9 9.3 1.4 9.4 0.1 4.4 5 0 0 5 5 4 0 Zinc-finger of C2H2 type CK_II_beta PF01214.18 EGE08238.1 - 0.12 12.2 7.8 2 8.2 0.8 2.7 1 1 1 2 2 2 0 Casein kinase II regulatory subunit zf_C2H2_ZHX PF18387.1 EGE08238.1 - 0.15 11.7 8.4 2.8 7.7 0.1 3.8 1 1 3 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 EGE08238.1 - 0.3 11.9 6.2 4.1 8.2 0.4 2.8 1 1 0 2 2 2 0 zinc-ribbon family zf-C2H2_8 PF15909.5 EGE08238.1 - 0.43 10.9 6.1 3.3 8.1 1.7 2.7 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 EGE08238.1 - 1.2 9.9 13.2 1.1 10.0 1.9 2.9 3 1 0 3 3 2 0 TRAF-type zinc finger DUF3268 PF11672.8 EGE08238.1 - 2 8.8 6.9 4.9 7.5 0.4 2.9 3 0 0 3 3 2 0 zinc-finger-containing domain zf-C2H2_11 PF16622.5 EGE08238.1 - 2.6 7.9 9.1 3.1 7.6 0.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type C5HCH PF17982.1 EGE08238.1 - 4.6 7.5 9.1 23 5.2 0.1 3.8 4 0 0 4 4 4 0 NSD Cys-His rich domain zinc-ribbons_6 PF07191.12 EGE08238.1 - 8.1 6.5 8.1 41 4.2 3.3 3.0 1 1 1 2 2 2 0 zinc-ribbons zf-RRPl_C4 PF17026.5 EGE08238.1 - 9.5 6.4 8.3 44 4.2 7.7 2.5 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type SapB_1 PF05184.15 EGE08241.1 - 0.052 13.6 0.6 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Ca_hom_mod PF14798.6 EGE08244.1 - 0.039 13.1 0.1 0.057 12.5 0.1 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator PHO4 PF01384.20 EGE08245.1 - 4.4e-45 154.2 5.4 4.8e-45 154.1 5.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family Med14 PF08638.11 EGE08246.1 - 2.3e-32 112.0 0.0 5e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 FAM199X PF15814.5 EGE08246.1 - 0.83 8.7 5.6 1.8 7.5 5.6 1.5 1 0 0 1 1 1 0 Protein family FAM199X DWNN PF08783.11 EGE08247.1 - 4.7e-10 39.6 1.3 0.00011 22.4 0.1 2.6 1 1 1 2 2 2 2 DWNN domain zf-CCHC_2 PF13696.6 EGE08247.1 - 5.9e-09 35.6 5.0 5.9e-09 35.6 5.0 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EGE08247.1 - 9.1e-05 22.4 1.0 0.00021 21.2 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 EGE08247.1 - 0.03 14.7 6.2 0.071 13.5 6.2 1.7 1 0 0 1 1 1 0 Ring finger domain DUF3905 PF13045.6 EGE08247.1 - 0.066 13.2 1.0 14 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3905) zf-CCHC_3 PF13917.6 EGE08247.1 - 0.071 13.1 1.9 0.076 13.0 0.2 2.0 2 0 0 2 2 2 0 Zinc knuckle FYVE_2 PF02318.16 EGE08247.1 - 0.12 12.6 1.8 0.35 11.1 1.8 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.6 EGE08247.1 - 0.3 10.9 5.8 0.63 9.9 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EGE08247.1 - 1.8 8.5 8.0 4.3 7.3 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGE08247.1 - 2 8.6 8.2 6 7.1 8.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGE08247.1 - 4.6 7.2 15.9 0.089 12.6 8.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ndc1_Nup PF09531.10 EGE08247.1 - 5.4 5.6 7.1 7.5 5.1 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1272 PF06906.11 EGE08247.1 - 7.8 6.7 10.5 0.31 11.1 4.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) Presenilin PF01080.17 EGE08247.1 - 9.3 4.9 11.6 21 3.7 11.6 1.6 1 0 0 1 1 1 0 Presenilin Nucleoporin_C PF03177.14 EGE08248.1 - 1.1e-169 566.0 10.7 1.4e-169 565.7 10.7 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EGE08248.1 - 9e-56 189.4 0.0 1.3e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.15 EGE08249.1 - 0.0057 17.5 2.9 0.0079 17.0 2.9 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family OST3_OST6 PF04756.13 EGE08250.1 - 1.6e-102 342.8 0.0 2.1e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 EGE08250.1 - 0.0068 17.2 1.9 0.0075 17.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function with HXXEE motif Thioredoxin PF00085.20 EGE08250.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MerC PF03203.14 EGE08250.1 - 0.22 12.0 4.8 3.5 8.1 0.3 3.1 3 0 0 3 3 3 0 MerC mercury resistance protein GAS PF13851.6 EGE08251.1 - 5.7e-05 22.6 15.7 0.0003 20.2 15.6 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 EGE08251.1 - 5.7e-05 23.9 10.0 5.7e-05 23.9 10.0 3.3 3 1 0 3 3 2 1 cGMP-dependent protein kinase interacting domain PI3K_P85_iSH2 PF16454.5 EGE08251.1 - 0.0013 18.4 16.2 0.023 14.3 16.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HALZ PF02183.18 EGE08251.1 - 0.0063 16.7 2.5 0.96 9.7 0.0 3.2 2 1 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.15 EGE08251.1 - 0.0077 16.0 6.4 0.023 14.5 0.1 3.0 2 1 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.21 EGE08251.1 - 0.016 15.3 0.3 0.016 15.3 0.3 3.2 3 1 1 4 4 3 0 bZIP transcription factor Phlebovirus_NSM PF07246.11 EGE08251.1 - 0.039 13.3 10.0 0.014 14.7 7.1 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CENP-F_leu_zip PF10473.9 EGE08251.1 - 0.04 14.0 18.6 0.16 12.0 16.1 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 EGE08251.1 - 0.1 12.5 12.1 0.022 14.6 7.0 2.1 1 1 1 2 2 2 0 Sec34-like family Mod_r PF07200.13 EGE08251.1 - 0.13 12.4 17.5 0.067 13.3 4.9 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TolA_bind_tri PF16331.5 EGE08251.1 - 0.23 11.6 13.7 3.6 7.8 8.5 3.2 1 1 1 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 EGE08251.1 - 0.25 11.8 8.9 0.68 10.4 0.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 EGE08251.1 - 0.43 10.9 8.0 1.3 9.3 3.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cnn_1N PF07989.11 EGE08251.1 - 0.44 10.7 11.4 1.3 9.2 1.3 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 EGE08251.1 - 0.54 10.2 7.1 0.96 9.4 0.3 3.1 1 1 2 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3450 PF11932.8 EGE08251.1 - 0.63 9.3 13.1 2.5 7.4 12.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 EGE08251.1 - 0.79 10.1 17.8 3.3 8.1 17.8 2.1 1 1 0 1 1 1 0 Fez1 UPF1_Zn_bind PF09416.10 EGE08251.1 - 0.95 9.4 3.2 1.3 9.0 1.6 1.9 1 1 1 2 2 2 0 RNA helicase (UPF2 interacting domain) APG6_N PF17675.1 EGE08251.1 - 1.1 9.8 19.1 2.3 8.7 3.8 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 EGE08251.1 - 2.3 8.3 19.3 0.15 12.1 5.5 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EGE08251.1 - 2.4 8.7 19.5 5.4 7.5 6.3 4.0 1 1 1 2 2 2 0 Cell division protein ZapB IFP_35_N PF07334.13 EGE08251.1 - 3.4 7.8 7.0 15 5.7 0.1 3.8 3 1 1 4 4 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4200 PF13863.6 EGE08251.1 - 3.4 8.1 13.2 14 6.1 13.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 EGE08251.1 - 5.1 4.9 8.7 8.4 4.2 8.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.13 EGE08251.1 - 5.4 6.5 11.4 17 4.9 6.2 2.3 1 1 1 2 2 2 0 fzo-like conserved region Cep57_CLD_2 PF14197.6 EGE08251.1 - 6.7 6.9 15.1 0.27 11.3 2.1 3.5 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 EGE08251.1 - 6.8 5.1 4.8 9.7 4.6 4.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.18 EGE08251.1 - 7.3 5.8 8.3 12 5.1 7.7 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ArAE_2_N PF10337.9 EGE08251.1 - 9.8 5.1 7.2 14 4.6 7.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Complex1_LYR PF05347.15 EGE08252.1 - 0.0014 18.7 0.2 0.0024 17.9 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zinc_ribbon_6 PF14599.6 EGE08253.1 - 9.4e-19 67.2 0.0 1.5e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon MFMR_assoc PF16596.5 EGE08253.1 - 0.088 13.3 3.6 0.27 11.7 3.6 1.8 1 1 0 1 1 1 0 Disordered region downstream of MFMR CENP-B_dimeris PF09026.10 EGE08253.1 - 5.6 7.4 9.2 10 6.6 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rrn6 PF10214.9 EGE08254.1 - 1.3e-216 722.0 6.0 1.6e-216 721.7 6.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EGE08255.1 - 3.1e-24 85.0 0.0 1.3e-23 83.0 0.0 2.1 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF334 PF03904.13 EGE08255.1 - 0.63 9.5 8.7 0.86 9.1 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ERM PF00769.19 EGE08255.1 - 0.79 9.5 20.5 1.1 9.0 20.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 EGE08255.1 - 2.2 7.3 15.6 3.1 6.8 15.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EGE08255.1 - 2.9 5.7 8.7 3.6 5.4 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ku_C PF03730.14 EGE08255.1 - 3.9 8.3 7.4 1.3 9.8 3.4 2.0 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm Calpain_III PF01067.22 EGE08255.1 - 4.1 7.7 5.9 6.3 7.1 5.9 1.2 1 0 0 1 1 1 0 Calpain large subunit, domain III LMBR1 PF04791.16 EGE08255.1 - 4.4 6.1 4.8 4.9 5.9 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 EGE08255.1 - 7.8 4.9 7.3 10 4.5 7.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 EGE08256.1 - 3e-23 81.7 13.1 2.2e-08 34.6 0.3 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08256.1 - 2.5e-15 56.5 0.6 0.00016 21.9 0.5 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGE08256.1 - 0.00065 18.3 0.0 0.0015 17.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 EGE08256.1 - 0.0008 19.3 0.0 0.31 10.9 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EGE08256.1 - 0.0013 18.1 0.3 2.3 7.5 0.0 3.4 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EGE08256.1 - 0.003 16.3 0.2 0.72 8.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGE08256.1 - 0.0076 16.7 0.4 2.2 8.9 0.0 3.6 3 1 0 3 3 3 1 PQQ-like domain Hira PF07569.11 EGE08256.1 - 0.04 13.6 0.1 5.5 6.6 0.0 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 EGE08256.1 - 0.11 11.5 0.5 8 5.3 0.0 3.1 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGE08256.1 - 0.12 11.1 0.2 1.5 7.5 0.1 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Ribosomal_L32p PF01783.23 EGE08257.1 - 2.6e-14 53.2 6.5 3.9e-14 52.7 6.5 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.7 EGE08257.1 - 0.0054 16.7 0.8 0.0086 16.1 0.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 EGE08257.1 - 0.033 14.2 0.6 0.047 13.7 0.6 1.2 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.11 EGE08257.1 - 0.047 13.6 0.8 0.087 12.8 0.8 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 EGE08257.1 - 0.16 11.5 5.1 0.4 10.2 5.3 1.6 1 1 0 1 1 1 0 zinc-ribbon domain CpXC PF14353.6 EGE08257.1 - 0.24 11.4 1.6 1.6 8.8 1.6 2.0 1 1 1 2 2 2 0 CpXC protein Zn-ribbon_8 PF09723.10 EGE08257.1 - 0.54 10.4 4.5 7.1 6.8 0.4 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EGE08257.1 - 4.3 7.4 6.4 3.3 7.8 0.3 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-XS PF03470.14 EGE08257.1 - 6.7 7.1 8.7 19 5.6 0.2 3.2 3 0 0 3 3 3 0 XS zinc finger domain Septin PF00735.18 EGE08258.1 - 1.4e-112 375.6 0.7 1.6e-112 375.4 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGE08258.1 - 7.6e-08 32.4 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGE08258.1 - 5e-06 26.0 0.0 8.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EGE08258.1 - 5.3e-05 23.2 0.5 0.00027 20.9 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGE08258.1 - 0.00028 20.5 0.8 0.016 14.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGE08258.1 - 0.00051 20.1 0.3 1.5 8.9 0.0 2.5 1 1 0 2 2 2 2 Dynamin family NB-ARC PF00931.22 EGE08258.1 - 0.0033 16.6 0.1 0.0058 15.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGE08258.1 - 0.005 17.2 0.0 0.012 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGE08258.1 - 0.0059 16.1 0.1 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGE08258.1 - 0.009 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGE08258.1 - 0.016 15.7 0.3 0.035 14.6 0.3 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EGE08258.1 - 0.051 12.7 0.6 0.39 9.8 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EGE08258.1 - 0.079 12.3 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EGE08258.1 - 0.085 11.9 0.1 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGE08258.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGE08258.1 - 0.087 12.6 0.3 0.41 10.4 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain Roc PF08477.13 EGE08258.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Guanylate_kin PF00625.21 EGE08259.1 - 6.2e-62 208.5 0.0 7.5e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EGE08259.1 - 1.7e-06 28.5 0.1 2.4e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGE08259.1 - 7.6e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EGE08259.1 - 0.00012 22.7 0.2 0.0005 20.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE08259.1 - 0.00013 22.1 0.4 0.0027 17.9 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGE08259.1 - 0.00017 21.9 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGE08259.1 - 0.00084 19.9 0.0 0.0018 18.8 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 EGE08259.1 - 0.00093 19.5 0.1 0.002 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE08259.1 - 0.0012 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EGE08259.1 - 0.0038 17.0 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGE08259.1 - 0.0051 16.5 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EGE08259.1 - 0.0058 16.2 0.0 0.0091 15.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EGE08259.1 - 0.0094 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 EGE08259.1 - 0.0095 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 EGE08259.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGE08259.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGE08259.1 - 0.02 14.6 0.1 0.092 12.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EGE08259.1 - 0.02 15.3 0.0 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGE08259.1 - 0.022 14.7 0.1 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EGE08259.1 - 0.027 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGE08259.1 - 0.046 13.6 0.1 0.084 12.8 0.1 1.6 1 1 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 EGE08259.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein T2SSE PF00437.20 EGE08259.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EGE08259.1 - 0.056 12.7 0.0 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EGE08259.1 - 0.066 12.8 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EGE08259.1 - 0.086 13.3 0.1 0.22 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGE08259.1 - 0.1 13.0 0.5 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EGE08259.1 - 0.14 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain dNK PF01712.19 EGE08259.1 - 0.14 12.0 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase Sigma54_activat PF00158.26 EGE08259.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain GRAB PF10375.9 EGE08260.1 - 5.2e-08 32.5 0.2 1.1e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 EGE08260.1 - 0.0055 16.2 59.1 0.53 9.7 26.0 3.2 1 1 2 3 3 3 3 Golgin subfamily A member 5 APC_N_CC PF16689.5 EGE08260.1 - 0.0099 15.9 4.1 0.0099 15.9 4.1 4.2 4 0 0 4 4 4 1 Coiled-coil N-terminus of APC, dimerisation domain Fez1 PF06818.15 EGE08260.1 - 0.011 16.1 54.8 0.014 15.9 6.7 3.4 2 1 0 3 3 3 0 Fez1 Baculo_PEP_C PF04513.12 EGE08260.1 - 0.038 14.0 14.0 1.7 8.7 7.0 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 EGE08260.1 - 0.077 13.2 20.0 3.9 7.8 0.0 6.2 4 1 2 6 6 6 0 Homeobox associated leucine zipper FAM184 PF15665.5 EGE08260.1 - 0.11 12.2 49.6 0.15 11.8 12.3 3.3 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B FliJ PF02050.16 EGE08260.1 - 0.24 11.6 45.5 0.085 13.1 16.9 3.7 1 1 2 3 3 3 0 Flagellar FliJ protein DUF3584 PF12128.8 EGE08260.1 - 0.45 8.0 49.1 0.54 7.7 34.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 EGE08260.1 - 2.4 7.0 55.2 4.3 6.1 18.1 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein CCCAP PF15964.5 EGE08260.1 - 2.9 6.1 52.3 3.5 5.8 23.5 2.1 1 1 1 2 2 2 0 Centrosomal colon cancer autoantigen protein family DUF641 PF04859.12 EGE08260.1 - 4.2 7.7 39.6 2 8.8 5.7 4.7 2 1 3 5 5 5 0 Plant protein of unknown function (DUF641) NPV_P10 PF05531.12 EGE08260.1 - 4.5 7.8 13.0 11 6.6 0.1 4.5 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 EGE08260.1 - 4.7 7.4 66.2 0.095 12.9 19.9 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EGE08260.1 - 5.6 7.1 29.7 0.69 10.1 2.0 3.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.21 EGE08260.1 - 8.7 5.8 50.9 25 4.3 25.5 3.2 1 1 1 2 2 2 0 Intermediate filament protein NFACT-R_1 PF05670.13 EGE08261.1 - 2.1e-40 137.7 0.1 3.1e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain TBCC PF07986.12 EGE08261.1 - 0.16 11.7 0.0 0.86 9.3 0.0 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor C DAO PF01266.24 EGE08264.1 - 1.1e-52 179.8 0.0 1.8e-52 179.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EGE08264.1 - 1.9e-43 147.3 0.1 3.3e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EGE08264.1 - 4.1e-10 39.3 0.0 9e-10 38.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGE08264.1 - 6.6e-07 29.0 0.2 5.5e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE08264.1 - 7.5e-05 22.1 0.9 0.00067 19.0 0.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGE08264.1 - 0.00045 19.4 0.2 0.015 14.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGE08264.1 - 0.0036 17.5 0.2 0.013 15.7 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EGE08264.1 - 0.0046 16.8 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGE08264.1 - 0.015 14.0 0.3 0.026 13.2 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_34 PF11312.8 EGE08264.1 - 0.021 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase FAD_binding_3 PF01494.19 EGE08264.1 - 0.032 13.5 0.5 0.19 10.9 0.6 2.0 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EGE08264.1 - 0.041 13.1 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGE08264.1 - 0.046 14.3 0.4 0.16 12.5 0.1 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGE08264.1 - 0.11 11.5 0.0 0.68 8.9 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein p450 PF00067.22 EGE08265.1 - 5.5e-65 219.9 0.0 6.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.10 EGE08266.1 - 9e-28 96.6 0.2 1.1e-27 96.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Rogdi_lz PF10259.9 EGE08266.1 - 0.0076 15.7 0.2 0.0083 15.6 0.2 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein APG6_N PF17675.1 EGE08266.1 - 0.016 15.7 0.1 0.022 15.3 0.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 EGE08266.1 - 0.023 15.1 0.9 0.037 14.5 0.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EGE08266.1 - 0.036 14.3 0.8 0.036 14.3 0.8 1.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.11 EGE08267.1 - 7.3e-19 67.4 2.0 1.6e-18 66.3 2.0 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EGE08267.1 - 1.7e-10 40.5 8.9 1.7e-10 40.5 8.9 2.5 2 0 0 2 2 2 1 Shugoshin C terminus PPI_Ypi1 PF07491.11 EGE08268.1 - 3.4e-25 87.6 2.4 3.4e-25 87.6 2.4 1.8 1 1 1 2 2 2 1 Protein phosphatase inhibitor Glypican PF01153.19 EGE08268.1 - 0.45 9.3 2.1 0.55 9.0 2.1 1.2 1 0 0 1 1 1 0 Glypican YL1 PF05764.13 EGE08268.1 - 0.74 9.9 11.4 1 9.4 10.5 1.6 1 1 1 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.6 EGE08268.1 - 7.1 7.1 8.0 4 7.9 6.2 1.6 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ALAD PF00490.21 EGE08269.1 - 1.8e-78 263.9 0.0 2.2e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mac_assoc PF16628.5 EGE08270.1 - 1.5e-61 207.9 12.0 1.5e-61 207.9 12.0 3.5 3 1 0 3 3 3 1 Unstructured region on maltose acetyltransferase Hexapep PF00132.24 EGE08270.1 - 1.1e-11 44.0 6.2 1.1e-07 31.2 0.3 3.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 EGE08270.1 - 3.6e-10 39.8 8.8 6.1e-10 39.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 EGE08270.1 - 7.8e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EGE08270.1 - 1e-06 28.4 5.4 8.7e-06 25.4 0.4 2.8 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase FAD_binding_3 PF01494.19 EGE08271.1 - 8.5e-22 77.9 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGE08271.1 - 3.8e-07 29.6 0.1 9.9e-07 28.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE08271.1 - 1.8e-06 28.1 1.8 5.3e-06 26.6 1.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGE08271.1 - 3e-06 27.1 6.4 0.014 15.0 5.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE08271.1 - 1.7e-05 24.1 7.2 2.5e-05 23.6 6.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGE08271.1 - 0.00032 19.5 0.5 0.0047 15.7 2.0 1.9 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 EGE08271.1 - 0.00094 18.3 0.0 0.0015 17.6 0.0 1.4 1 1 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 EGE08271.1 - 0.0013 17.9 2.6 0.0018 17.5 2.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGE08271.1 - 0.002 17.5 5.0 0.0032 16.9 5.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGE08271.1 - 0.0031 18.0 1.7 0.042 14.4 2.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGE08271.1 - 0.011 15.1 0.9 0.28 10.4 0.6 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EGE08271.1 - 0.015 14.2 1.3 0.71 8.6 1.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EGE08271.1 - 0.019 14.2 0.9 0.031 13.5 0.9 1.2 1 0 0 1 1 1 0 Thi4 family Rossmann-like PF10727.9 EGE08271.1 - 0.079 12.8 0.7 0.23 11.3 0.3 1.9 2 0 0 2 2 2 0 Rossmann-like domain 3HCDH_N PF02737.18 EGE08271.1 - 0.14 12.1 3.2 0.23 11.3 3.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGE08271.1 - 0.2 10.6 0.8 1.3 8.0 0.8 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGE08271.1 - 0.22 10.7 2.8 0.36 10.0 2.8 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGE08271.1 - 0.25 10.6 2.2 0.44 9.8 2.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EGE08271.1 - 0.29 10.7 0.9 0.79 9.3 0.7 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CRM1_C PF08767.11 EGE08272.1 - 1.3e-135 451.7 5.0 1.3e-135 451.7 5.0 2.9 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EGE08272.1 - 6e-42 143.2 9.0 1.8e-41 141.7 6.6 3.1 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGE08272.1 - 8.8e-34 115.0 4.1 4.7e-33 112.7 4.1 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGE08272.1 - 2.7e-29 101.0 0.7 2.7e-29 101.0 0.7 2.9 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGE08272.1 - 6e-20 70.5 1.3 1.4e-19 69.3 1.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF3385 PF11865.8 EGE08272.1 - 0.0027 17.6 0.3 0.29 11.0 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) HD_assoc PF13286.6 EGE08272.1 - 0.18 12.3 4.3 21 5.7 0.2 4.1 4 0 0 4 4 4 0 Phosphohydrolase-associated domain CIAPIN1 PF05093.13 EGE08273.1 - 6.5e-42 142.1 3.6 6.5e-42 142.1 3.6 2.0 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGE08273.1 - 6.1e-34 117.1 0.2 2.9e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus Rft-1 PF04506.13 EGE08274.1 - 3e-129 432.1 13.6 3.6e-129 431.8 13.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EGE08274.1 - 0.012 14.9 20.2 0.026 13.7 7.9 3.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 EGE08274.1 - 2 7.7 29.8 0.75 9.1 10.5 3.3 3 1 0 3 3 3 0 Polysaccharide biosynthesis protein Rep_fac-A_C PF08646.10 EGE08275.1 - 4.9e-47 159.3 4.8 8.6e-47 158.6 4.8 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EGE08275.1 - 5.5e-35 119.2 0.1 9.7e-35 118.4 0.1 1.4 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 EGE08275.1 - 1.1e-19 70.3 0.1 2.8e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 EGE08275.1 - 0.011 15.5 0.9 0.093 12.4 0.4 2.1 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 tRNA_anti-codon PF01336.25 EGE08275.1 - 0.013 15.4 0.1 11 6.1 0.0 3.3 2 1 1 3 3 3 0 OB-fold nucleic acid binding domain Ribosomal_L37ae PF01780.19 EGE08275.1 - 0.023 14.8 0.5 0.06 13.4 0.5 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4503 PF14951.6 EGE08275.1 - 0.032 12.7 0.3 0.05 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) DUF2293 PF10056.9 EGE08276.1 - 2.2e-29 101.5 1.1 5.6e-29 100.2 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) MHYT PF03707.16 EGE08278.1 - 5.9e-10 39.2 21.1 2e-09 37.4 1.1 4.6 4 1 0 4 4 4 2 Bacterial signalling protein N terminal repeat Pax2_C PF12403.8 EGE08278.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Paired-box protein 2 C terminal DUF4271 PF14093.6 EGE08278.1 - 7.4 6.4 12.6 1.2 9.0 7.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) HMA PF00403.26 EGE08279.1 - 1.5e-15 57.4 0.2 1.7e-15 57.2 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Vps4_C PF09336.10 EGE08279.1 - 0.0033 17.4 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Fer2_BFD PF04324.15 EGE08279.1 - 0.11 12.8 0.1 0.37 11.2 0.1 1.8 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Tcp11 PF05794.13 EGE08280.1 - 1.4e-105 353.9 0.1 1.4e-105 353.9 0.1 1.9 3 0 0 3 3 3 1 T-complex protein 11 PXA PF02194.15 EGE08281.1 - 1e-43 149.5 0.1 5.6e-43 147.0 0.1 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EGE08281.1 - 5.6e-28 97.7 0.0 2e-27 96.0 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EGE08281.1 - 8.5e-19 67.6 0.1 2e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EGE08281.1 - 2.6e-11 43.8 0.0 6.4e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.32 EGE08283.1 - 4.5e-18 65.3 5.9 0.002 18.9 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08283.1 - 2.4e-07 30.9 0.0 0.019 15.3 0.0 4.5 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE08283.1 - 0.0052 15.8 0.5 0.1 11.6 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGE08283.1 - 0.14 10.8 1.3 3.8 6.1 0.1 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 tRNA-synt_1g PF09334.11 EGE08284.1 - 2.1e-148 494.3 0.0 3.1e-148 493.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGE08284.1 - 1.3e-07 30.3 0.0 6.9e-05 21.3 0.0 3.5 3 1 1 4 4 4 2 tRNA synthetases class I (I, L, M and V) BRF1 PF07741.13 EGE08284.1 - 0.27 11.6 6.6 0.59 10.5 6.6 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PepSY PF03413.19 EGE08284.1 - 0.31 11.6 3.8 15 6.2 0.0 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Laminin_EGF PF00053.24 EGE08284.1 - 0.35 11.1 3.8 0.6 10.3 3.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain AP3D1 PF06375.11 EGE08284.1 - 0.72 10.1 7.3 1.2 9.4 7.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Elongin_A PF06881.11 EGE08284.1 - 5.3 7.6 8.4 4 8.0 5.9 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Yae1_N PF09811.9 EGE08285.1 - 4.7e-07 29.4 3.6 7.5e-07 28.8 3.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal WD40 PF00400.32 EGE08286.1 - 3.1e-31 106.9 18.3 3.9e-08 33.8 0.1 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08286.1 - 1.6e-11 44.3 4.5 0.01 16.1 0.1 4.8 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGE08286.1 - 0.15 11.0 0.4 0.26 10.3 0.4 1.3 1 0 0 1 1 1 0 Coatomer WD associated region bZIP_2 PF07716.15 EGE08288.1 - 0.00012 22.0 10.6 0.00024 21.1 10.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGE08288.1 - 0.00015 21.8 9.4 0.0036 17.4 4.7 2.3 1 1 1 2 2 2 2 bZIP transcription factor Pox_A_type_inc PF04508.12 EGE08288.1 - 0.017 15.0 1.2 0.017 15.0 1.2 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2796 PF10986.8 EGE08288.1 - 0.05 13.6 0.1 0.078 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) ChaC PF04752.12 EGE08289.1 - 7e-49 166.3 0.2 8.5e-48 162.8 0.2 1.9 1 1 0 1 1 1 1 ChaC-like protein RHS PF03527.14 EGE08289.1 - 0.12 12.1 0.2 11 5.8 0.0 2.4 2 0 0 2 2 2 0 RHS protein EF-hand_1 PF00036.32 EGE08290.1 - 4.2e-21 72.9 5.6 7e-07 28.4 0.1 5.1 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGE08290.1 - 5.6e-18 63.3 3.3 0.0011 18.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGE08290.1 - 2.4e-17 62.5 8.6 2.6e-09 36.8 0.1 4.6 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_7 PF13499.6 EGE08290.1 - 2e-16 60.2 5.5 1.1e-07 32.1 0.0 3.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGE08290.1 - 2.8e-15 55.0 6.5 9.1e-05 21.8 0.4 4.7 4 1 0 4 4 4 3 EF hand EF-hand_14 PF17959.1 EGE08290.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain G6PD_C PF02781.16 EGE08291.1 - 1e-100 336.7 0.0 1.4e-99 333.0 0.0 2.1 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGE08291.1 - 3.8e-61 206.8 0.0 8.7e-61 205.6 0.0 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ribosomal_L12_N PF16320.5 EGE08292.1 - 3.7 7.3 11.8 7.1 6.4 11.8 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain FAM176 PF14851.6 EGE08293.1 - 0.1 12.2 3.3 0.13 12.0 3.3 1.2 1 0 0 1 1 1 0 FAM176 family Cytomega_UL84 PF06284.11 EGE08293.1 - 0.72 8.2 3.4 0.76 8.2 3.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TMEM119 PF15724.5 EGE08293.1 - 0.99 9.4 4.7 1.1 9.3 4.7 1.1 1 0 0 1 1 1 0 TMEM119 family DNA_pol_phi PF04931.13 EGE08293.1 - 7.1 4.6 6.2 7.8 4.5 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 EGE08294.1 - 5.6e-45 153.8 56.4 5.6e-44 150.5 55.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGE08294.1 - 1.2e-18 66.9 20.7 2.5e-18 65.9 20.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGE08294.1 - 7.6e-10 38.2 15.5 7.6e-10 38.2 15.5 3.5 4 1 0 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 EGE08294.1 - 2.5 6.3 21.2 0.25 9.6 4.1 3.6 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family CBS PF00571.28 EGE08296.1 - 4.9e-05 23.7 0.0 3.4 8.2 0.0 3.3 1 1 2 3 3 3 3 CBS domain Mito_carr PF00153.27 EGE08297.1 - 4.1e-48 161.3 7.0 3.3e-19 68.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S10 PF00450.22 EGE08298.1 - 1.7e-114 383.5 0.0 2.1e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CCT_2 PF09425.10 EGE08298.1 - 0.067 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Divergent CCT motif RNA_Me_trans PF04252.13 EGE08299.1 - 4.3e-80 268.0 0.0 4.9e-80 267.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Endosulfine PF04667.17 EGE08300.1 - 1.3e-19 70.1 0.3 2.9e-19 69.0 0.3 1.6 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HEAT PF02985.22 EGE08302.1 - 2.1e-11 43.0 15.4 9.3e-05 22.4 0.0 7.3 9 1 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 EGE08302.1 - 7.1e-09 36.0 8.4 1.1e-06 29.0 0.0 6.1 6 1 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGE08302.1 - 1.4e-07 31.8 7.0 0.00023 21.5 0.1 5.6 3 2 2 5 5 5 2 HEAT repeats CLASP_N PF12348.8 EGE08302.1 - 4.9e-07 29.6 0.8 0.023 14.3 0.0 3.7 3 0 0 3 3 3 2 CLASP N terminal IBN_N PF03810.19 EGE08302.1 - 2.3e-06 27.4 1.8 0.001 19.0 0.1 3.3 3 1 0 3 3 3 2 Importin-beta N-terminal domain DUF3385 PF11865.8 EGE08302.1 - 0.00036 20.5 2.7 3.6 7.5 0.8 3.8 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) Arm PF00514.23 EGE08302.1 - 0.0052 16.8 1.2 20 5.4 0.2 4.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cse1 PF08506.10 EGE08302.1 - 0.0068 15.3 0.0 1.6 7.5 0.0 3.2 3 0 0 3 3 3 1 Cse1 DUF3535 PF12054.8 EGE08302.1 - 0.01 15.1 0.3 0.047 12.9 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3535) Sec7_N PF12783.7 EGE08302.1 - 0.042 13.7 0.2 2.1 8.2 0.0 2.9 1 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 EGE08302.1 - 0.061 13.9 1.1 24 5.6 0.0 4.4 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HycH PF07450.11 EGE08302.1 - 0.11 12.9 0.3 4.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH NUC173 PF08161.12 EGE08302.1 - 0.12 12.1 2.0 42 3.7 0.0 3.8 3 1 1 4 4 4 0 NUC173 domain Uso1_p115_head PF04869.14 EGE08302.1 - 0.74 8.9 4.5 0.68 9.0 0.3 2.6 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region ANAPC4 PF12896.7 EGE08303.1 - 1.5e-62 210.8 1.5 2.3e-62 210.2 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGE08303.1 - 1.4e-25 89.4 0.0 5.2e-25 87.6 0.0 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain VWA PF00092.28 EGE08305.1 - 3.1e-07 30.8 0.0 4.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGE08305.1 - 0.00043 20.9 0.0 0.0009 19.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tannase PF07519.11 EGE08306.1 - 1.9e-101 340.3 0.1 2.2e-101 340.1 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 EGE08306.1 - 0.0039 16.9 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE08306.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 EGE08307.1 - 5.1e-09 36.1 9.6 1e-08 35.1 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE08307.1 - 4.2e-07 29.1 3.4 3e-06 26.3 0.3 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Tox-HNH-HHH PF15637.6 EGE08308.1 - 0.11 12.7 2.3 0.36 11.0 1.1 2.3 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif APH PF01636.23 EGE08309.1 - 2.3e-12 47.3 0.0 3.7e-12 46.7 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_16 PF10294.9 EGE08310.1 - 2.3e-22 79.6 0.0 3.7e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGE08310.1 - 0.00067 19.5 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ABC_tran PF00005.27 EGE08311.1 - 3.1e-26 92.5 0.0 3.8e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGE08311.1 - 3.6e-12 46.7 0.4 0.002 18.0 0.0 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE08311.1 - 7.5e-08 32.1 0.1 0.00039 19.9 0.1 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 EGE08311.1 - 1.2e-07 31.7 3.1 8e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_5 PF07728.14 EGE08311.1 - 0.043 13.8 0.5 15 5.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE08311.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain VPS28 PF03997.12 EGE08312.1 - 7.6e-74 247.5 0.8 8.8e-74 247.3 0.8 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 EGE08313.1 - 6.7e-129 429.4 0.1 2.1e-128 427.7 0.0 1.9 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 EGE08313.1 - 0.00021 19.7 1.2 0.00021 19.7 1.2 3.0 2 1 1 3 3 3 2 Nop14-like family Piwi PF02171.17 EGE08314.1 - 4.2e-72 242.9 0.0 6.2e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EGE08314.1 - 9.3e-18 65.2 0.9 3e-17 63.5 0.9 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EGE08314.1 - 9.3e-16 57.2 0.0 2.9e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EGE08314.1 - 8.9e-08 32.0 0.3 4.7e-07 29.7 0.0 2.4 3 0 0 3 3 3 1 PAZ domain ArgoL2 PF16488.5 EGE08314.1 - 3.2e-06 27.4 0.3 9e-06 25.9 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain MoaC PF01967.21 EGE08315.1 - 1.1e-43 148.6 0.1 1.8e-43 147.9 0.1 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EGE08315.1 - 3.6e-37 127.1 0.0 4.4e-36 123.6 0.0 2.3 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGE08315.1 - 5.1e-27 95.3 0.1 9.9e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGE08315.1 - 8.3e-05 22.9 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain AA_permease PF00324.21 EGE08317.1 - 1.5e-143 478.9 36.3 1.8e-143 478.6 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EGE08317.1 - 2.5e-36 125.4 38.3 3e-36 125.2 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.27 EGE08318.1 - 2.5e-45 154.4 0.9 1.4e-22 80.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGE08318.1 - 9.6e-12 45.3 6.7 0.00041 20.2 0.1 4.1 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE08318.1 - 1.4e-08 34.4 3.5 0.046 13.2 0.8 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGE08318.1 - 2e-06 27.8 0.4 0.13 12.3 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EGE08318.1 - 2.4e-06 28.2 11.6 0.0003 21.3 4.2 3.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGE08318.1 - 2.7e-06 27.0 0.4 0.0096 15.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EGE08318.1 - 9.2e-05 22.7 0.1 0.055 13.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE08318.1 - 0.00016 22.0 0.2 0.27 11.5 0.0 2.9 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE08318.1 - 0.00024 21.0 0.1 0.35 10.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EGE08318.1 - 0.0016 18.2 0.1 1.5 8.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EGE08318.1 - 0.0018 18.3 0.8 1.8 8.4 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 EGE08318.1 - 0.0031 18.0 0.0 3.5 8.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EGE08318.1 - 0.0031 17.1 0.1 0.13 11.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EGE08318.1 - 0.0036 17.5 3.8 2 8.5 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 EGE08318.1 - 0.0047 17.4 0.0 1.7 9.1 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_tran_Xtn PF12848.7 EGE08318.1 - 0.006 16.6 1.1 0.015 15.3 1.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 EGE08318.1 - 0.013 15.6 0.1 7.8 6.5 0.1 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGE08318.1 - 0.013 15.9 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase CCDC-167 PF15188.6 EGE08318.1 - 0.015 15.7 6.5 1.6 9.1 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Viral_helicase1 PF01443.18 EGE08318.1 - 0.02 14.6 0.1 3.8 7.2 0.0 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 EGE08318.1 - 0.027 13.5 1.4 3.5 6.5 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EGE08318.1 - 0.029 14.4 1.1 1 9.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGE08318.1 - 0.039 13.1 0.1 7.1 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EGE08318.1 - 0.043 13.0 1.1 1.8 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MobB PF03205.14 EGE08318.1 - 0.046 13.6 0.2 5.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 EGE08318.1 - 0.05 13.3 8.3 0.96 9.1 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain AAA_7 PF12775.7 EGE08318.1 - 0.057 12.9 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGE08318.1 - 0.059 12.7 0.4 0.69 9.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EGE08318.1 - 0.061 12.9 0.7 3 7.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EGE08318.1 - 0.091 12.3 0.2 2.7 7.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE08318.1 - 0.11 12.2 0.3 9.1 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGE08318.1 - 0.13 12.3 7.4 2.2 8.3 0.3 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_16 PF13191.6 EGE08318.1 - 1.5 9.2 9.4 15 5.9 3.4 3.2 2 2 0 2 2 2 0 AAA ATPase domain 2OG-FeII_Oxy_3 PF13640.6 EGE08319.1 - 9.5e-08 32.8 0.0 1.7e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ANAPC4_WD40 PF12894.7 EGE08320.1 - 5e-05 23.5 0.0 0.00043 20.5 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE08320.1 - 0.0014 19.4 0.2 0.013 16.3 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_S25 PF03297.15 EGE08321.1 - 2.7e-38 130.2 5.4 2.9e-38 130.1 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 EGE08321.1 - 0.0044 16.8 0.1 0.006 16.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EGE08321.1 - 0.017 15.5 0.1 0.023 15.0 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 EGE08321.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 EGE08321.1 - 0.04 13.5 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGE08321.1 - 0.072 13.0 0.3 0.098 12.6 0.3 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB MarR_2 PF12802.7 EGE08321.1 - 0.075 12.9 0.1 0.093 12.6 0.1 1.2 1 0 0 1 1 1 0 MarR family Cyt-b5 PF00173.28 EGE08322.1 - 5.7e-10 39.2 0.0 1.2e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 EGE08323.1 - 6e-70 235.2 0.4 9.2e-70 234.6 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EGE08323.1 - 5.3e-05 22.7 0.0 9.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGE08323.1 - 0.0017 17.8 0.0 0.0043 16.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGE08323.1 - 0.0032 17.5 0.0 0.0073 16.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGE08323.1 - 0.007 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGE08323.1 - 0.031 14.1 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 EGE08324.1 - 2e-21 76.5 0.0 2.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGE08324.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGE08324.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_2 PF00328.22 EGE08325.1 - 8.8e-13 48.3 0.0 3.1e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_4 PF13691.6 EGE08326.1 - 4.5e-27 93.5 0.2 1.2e-25 88.9 0.0 2.8 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EGE08326.1 - 2.2e-13 50.2 0.7 8.6e-06 25.4 0.1 2.4 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGE08326.1 - 0.00011 22.3 0.2 0.00024 21.1 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAD_binding_10 PF13460.6 EGE08327.1 - 4.9e-20 72.2 0.0 7.6e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGE08327.1 - 0.0086 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LAM_C PF12544.8 EGE08327.1 - 0.19 11.9 0.2 0.46 10.7 0.1 1.7 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Methyltransf_25 PF13649.6 EGE08328.1 - 6.2e-19 68.5 0.1 1.4e-18 67.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08328.1 - 7.3e-16 58.4 0.0 9.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE08328.1 - 1.8e-15 57.4 0.0 3.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08328.1 - 8.6e-13 48.3 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE08328.1 - 3.6e-10 40.5 0.0 6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGE08328.1 - 2.4e-09 36.9 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.16 EGE08328.1 - 1.1e-06 28.1 0.0 2.5e-05 23.6 0.0 2.5 1 1 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 EGE08328.1 - 2.2e-05 24.2 0.0 2.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.18 EGE08328.1 - 3.4e-05 23.4 0.2 0.19 11.2 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain MetW PF07021.12 EGE08328.1 - 9.4e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EGE08328.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.11 EGE08328.1 - 0.00043 20.0 0.0 0.0012 18.5 0.0 1.9 2 1 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 EGE08328.1 - 0.0005 19.1 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 EGE08328.1 - 0.00057 19.2 0.0 0.00069 19.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain TehB PF03848.14 EGE08328.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 EGE08328.1 - 0.0029 17.4 0.0 0.0089 15.8 0.0 1.7 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGE08328.1 - 0.0036 16.7 0.0 0.0054 16.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGE08328.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.13 EGE08328.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_PK PF05891.12 EGE08328.1 - 0.035 13.6 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 EGE08328.1 - 0.058 12.9 0.0 0.18 11.3 0.0 1.8 1 1 1 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 EGE08328.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FmrO PF07091.11 EGE08328.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Tubulin_3 PF14881.6 EGE08328.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin domain PrmA PF06325.13 EGE08328.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RE_Bsp6I PF09504.10 EGE08328.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 Bsp6I restriction endonuclease bZIP_1 PF00170.21 EGE08329.1 - 1.5e-08 34.6 9.3 1.5e-08 34.6 9.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGE08329.1 - 0.00038 20.5 11.1 0.00038 20.5 11.1 2.6 2 0 0 2 2 2 1 Basic region leucine zipper NST1 PF13945.6 EGE08329.1 - 1.7 8.7 25.9 3.2 7.8 25.9 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Macoilin PF09726.9 EGE08329.1 - 2.5 6.5 26.5 3.3 6.1 26.5 1.1 1 0 0 1 1 1 0 Macoilin family Sin_N PF04801.13 EGE08329.1 - 4.3 6.4 28.4 7.1 5.7 28.4 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region CDC27 PF09507.10 EGE08329.1 - 4.9 6.4 32.8 0.35 10.2 28.1 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Dus PF01207.17 EGE08330.1 - 2.2e-59 201.1 0.0 5.4e-59 199.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EGE08330.1 - 0.058 12.6 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF908 PF06012.12 EGE08330.1 - 0.15 11.5 0.4 6.3 6.1 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) APH PF01636.23 EGE08331.1 - 2e-11 44.3 0.0 9.9e-11 42.0 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE08331.1 - 6.6e-05 21.9 0.0 0.0004 19.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGE08331.1 - 0.059 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EGE08331.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Macro PF01661.21 EGE08333.1 - 6.1e-12 45.6 0.0 4.4e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Macro domain DUF5320 PF17253.2 EGE08333.1 - 0.013 16.5 0.3 0.026 15.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Pinin_SDK_N PF04697.13 EGE08333.1 - 0.17 12.6 0.2 0.24 12.0 0.2 1.3 1 0 0 1 1 1 0 pinin/SDK conserved region MSP1b PF03429.13 EGE08333.1 - 0.23 9.5 0.0 0.3 9.2 0.0 1.0 1 0 0 1 1 1 0 Major surface protein 1B CENP-X PF09415.10 EGE08334.1 - 1.7e-23 82.7 0.4 3.5e-23 81.7 0.4 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Paramyxo_ncap PF00973.19 EGE08334.1 - 1.4 7.8 5.2 1.9 7.3 5.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDHD PF02862.17 EGE08334.1 - 6.9 6.8 7.4 1.8 8.6 3.6 1.7 1 1 1 2 2 2 0 DDHD domain Mis12 PF05859.12 EGE08336.1 - 1.2e-47 161.3 0.0 2.1e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein ATG16 PF08614.11 EGE08336.1 - 0.028 14.6 1.5 0.16 12.1 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MitoNEET_N PF10660.9 EGE08336.1 - 0.094 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Trans_reg_C PF00486.28 EGE08337.1 - 0.014 15.4 0.8 0.056 13.5 0.1 2.0 1 1 0 2 2 2 0 Transcriptional regulatory protein, C terminal SLATT_4 PF18186.1 EGE08338.1 - 0.098 12.3 0.1 0.28 10.8 0.0 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF4131 PF13567.6 EGE08338.1 - 3.7 7.2 5.6 1.5 8.4 0.8 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) BCNT PF07572.12 EGE08339.1 - 1.6e-26 92.2 0.2 4.1e-26 90.8 0.2 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Pheromone PF08015.11 EGE08339.1 - 1.2 10.2 3.9 3.6 8.7 3.1 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone Acetyltransf_3 PF13302.7 EGE08340.1 - 6.4e-31 107.9 0.0 7.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGE08340.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGE08340.1 - 0.016 15.5 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Methyltransf_3 PF01596.17 EGE08341.1 - 1.2e-30 106.3 0.0 1.9e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EGE08341.1 - 5.6e-11 42.6 0.0 7.9e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGE08341.1 - 3.3e-10 40.9 0.0 8.4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08341.1 - 1.9e-08 34.2 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08341.1 - 3.5e-07 30.8 0.0 7.4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE08341.1 - 0.00038 19.9 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGE08341.1 - 0.0015 19.2 0.0 0.0065 17.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGE08341.1 - 0.0024 17.3 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 EGE08341.1 - 0.019 15.7 0.0 0.043 14.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EGE08341.1 - 0.038 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Response_reg PF00072.24 EGE08341.1 - 0.16 12.1 0.0 5.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain Spt20 PF12090.8 EGE08342.1 - 8.1e-54 182.7 0.8 8.1e-54 182.7 0.8 6.2 4 2 0 4 4 4 2 Spt20 family Serglycin PF04360.12 EGE08344.1 - 0.0044 17.0 3.4 0.0044 17.0 3.4 2.2 2 0 0 2 2 2 1 Serglycin JAB PF01398.21 EGE08345.1 - 0.14 12.1 0.4 0.35 10.9 0.1 1.7 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FragX_IP PF05994.11 EGE08347.1 - 0.072 11.1 0.0 0.082 10.9 0.0 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family TetR_C_19 PF17924.1 EGE08348.1 - 0.062 13.9 0.2 2.1 9.0 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Hexapep PF00132.24 EGE08350.1 - 2.2e-06 27.1 2.9 0.023 14.4 0.3 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGE08350.1 - 5.7e-06 25.5 0.1 9.7e-06 24.8 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 EGE08350.1 - 0.0006 19.5 0.0 0.00097 18.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EGE08350.1 - 0.019 13.2 0.2 0.026 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EGE08350.1 - 0.039 14.3 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain MMPL PF03176.15 EGE08351.1 - 0.091 11.7 2.6 2.1 7.2 0.2 2.2 2 0 0 2 2 2 0 MMPL family Mucin PF01456.17 EGE08354.1 - 1.6 8.7 14.8 2 8.4 14.4 1.2 1 1 0 1 1 1 0 Mucin-like glycoprotein Gemini_V2 PF01524.17 EGE08355.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Geminivirus V2 protein ELO PF01151.18 EGE08357.1 - 3.8e-09 36.5 0.0 5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Nuc_deoxyri_tr2 PF15891.5 EGE08357.1 - 0.0028 17.9 1.2 0.0051 17.1 1.2 1.4 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like SID-1_RNA_chan PF13965.6 EGE08357.1 - 0.24 9.8 0.3 0.32 9.3 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2072 PF09845.9 EGE08357.1 - 0.84 9.9 8.7 3.9 7.8 8.7 2.1 1 1 0 1 1 1 0 Zn-ribbon containing protein RskA PF10099.9 EGE08358.1 - 0.0075 16.6 0.9 0.012 15.9 0.9 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA WD40 PF00400.32 EGE08359.1 - 2.8e-05 24.8 2.4 0.013 16.4 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF123 PF01986.16 EGE08359.1 - 0.12 12.9 0.1 0.25 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 ANAPC4_WD40 PF12894.7 EGE08359.1 - 0.17 12.2 0.2 26 5.2 0.0 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 EGE08360.1 - 4.7 7.3 20.1 83 3.4 11.6 3.7 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ATG22 PF11700.8 EGE08361.1 - 7.7e-132 440.3 28.6 9.4e-132 440.0 28.6 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EGE08361.1 - 1.1e-11 44.3 32.9 4.2e-07 29.2 6.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Ras PF00071.22 EGE08362.1 - 8.3e-59 197.8 0.2 9.6e-59 197.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE08362.1 - 2.6e-36 124.5 0.2 4.4e-36 123.7 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE08362.1 - 1.1e-14 54.3 0.1 1.3e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGE08362.1 - 2.8e-07 30.3 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGE08362.1 - 6.2e-07 29.5 0.0 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGE08362.1 - 1.4e-06 27.9 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGE08362.1 - 2.1e-05 24.5 1.1 0.19 11.6 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGE08362.1 - 0.011 16.1 0.2 0.028 14.8 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGE08362.1 - 0.056 13.7 0.0 3.1 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAT PF03417.16 EGE08362.1 - 0.14 11.8 0.2 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Mitofilin PF09731.9 EGE08363.1 - 1.4e-153 513.0 28.3 1.8e-126 423.5 25.0 2.2 1 1 1 2 2 2 2 Mitochondrial inner membrane protein ATP-synt_B PF00430.18 EGE08363.1 - 0.014 15.4 19.1 0.41 10.7 8.2 2.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Focal_AT PF03623.13 EGE08363.1 - 0.049 13.6 1.6 0.12 12.4 0.2 2.1 1 1 1 2 2 2 0 Focal adhesion targeting region Ribosomal_L20 PF00453.18 EGE08363.1 - 0.069 13.2 2.3 0.16 12.1 2.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 ArnB_C PF18677.1 EGE08363.1 - 0.097 12.8 8.9 11 6.2 0.0 4.0 4 0 0 4 4 4 0 Archaellum regulatory network B, C-terminal domain DUF2205 PF10224.9 EGE08363.1 - 0.37 10.8 7.1 0.14 12.2 2.4 2.6 1 1 0 2 2 2 0 Short coiled-coil protein YqhG PF11079.8 EGE08363.1 - 0.55 9.2 3.4 0.93 8.4 3.4 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DUF4363 PF14276.6 EGE08363.1 - 4.2 7.5 10.7 1.6 8.9 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4363) DSBA PF01323.20 EGE08367.1 - 2.2e-14 53.7 0.0 2.5e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Bromodomain PF00439.25 EGE08368.1 - 2.7e-21 75.4 0.3 5e-21 74.6 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGE08368.1 - 9e-08 32.4 0.1 1.7e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE08368.1 - 4.9e-07 29.7 0.1 9.6e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE08368.1 - 5.3e-05 23.6 0.2 0.00012 22.4 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGE08368.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF4661 PF15576.6 EGE08369.1 - 5.7 6.8 11.7 5.6 6.8 2.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) Methyltransf_16 PF10294.9 EGE08370.1 - 1.1e-49 168.5 0.0 1.6e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EGE08370.1 - 1.6e-05 25.5 0.1 7.8e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08370.1 - 3.9e-05 23.5 0.1 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08370.1 - 0.00026 20.9 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE08370.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EGE08370.1 - 0.0011 19.7 0.1 0.0044 17.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain VWA_CoxE PF05762.14 EGE08370.1 - 0.017 14.5 0.1 0.039 13.3 0.1 1.6 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein PrmA PF06325.13 EGE08370.1 - 0.023 14.1 0.1 0.036 13.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Orn_Arg_deC_N PF02784.16 EGE08371.1 - 4.1e-83 278.5 0.0 6.7e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGE08371.1 - 6.3e-18 64.8 0.0 7.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EGE08371.1 - 0.01 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Luteo_P1-P2 PF08467.10 EGE08371.1 - 0.014 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase cobW PF02492.19 EGE08372.1 - 8.3e-42 142.8 0.0 1.2e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGE08372.1 - 0.00071 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 EGE08372.1 - 0.0011 18.8 0.0 0.005 16.7 0.0 2.0 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EGE08372.1 - 0.029 14.7 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGE08372.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.12 EGE08372.1 - 0.13 11.7 0.1 0.3 10.5 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_29 PF13555.6 EGE08372.1 - 0.16 11.8 0.4 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EGE08372.1 - 0.21 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SET PF00856.28 EGE08373.1 - 6.6e-07 29.9 0.1 1.2e-06 29.1 0.1 1.3 1 1 0 1 1 1 1 SET domain Glyco_transf_54 PF04666.13 EGE08374.1 - 1.1e-12 47.4 0.0 8.3e-09 34.7 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Cation_efflux PF01545.21 EGE08374.1 - 0.018 14.7 0.3 0.14 11.9 0.2 2.2 2 1 0 2 2 2 0 Cation efflux family DUF3431 PF11913.8 EGE08375.1 - 1.5e-87 292.9 0.0 1.8e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) RVT_1 PF00078.27 EGE08377.1 - 3.3e-30 105.3 0.1 4.6e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EGE08378.1 - 2.7e-13 49.8 0.2 4.4e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 EGE08378.1 - 1.9e-08 34.1 0.5 4.7e-08 32.8 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 EGE08378.1 - 0.0019 18.4 0.5 0.005 17.0 0.2 1.8 1 1 1 2 2 2 1 H2C2 zinc finger BCS1_N PF08740.11 EGE08382.1 - 6.4e-34 117.6 0.0 8.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGE08382.1 - 3.4e-18 66.3 0.0 1.2e-17 64.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EGE08382.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 EGE08382.1 - 0.02 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PPV_E1_C PF00519.17 EGE08382.1 - 0.027 13.3 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Papillomavirus helicase AAA_25 PF13481.6 EGE08382.1 - 0.038 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGE08382.1 - 0.051 13.3 0.2 0.15 11.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 EGE08382.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGE08382.1 - 0.14 12.1 0.1 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 EGE08383.1 - 9.6e-06 25.8 7.7 0.013 15.8 0.8 4.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08383.1 - 1.6e-05 24.7 1.1 2.3 8.6 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08383.1 - 0.00082 20.0 6.4 0.007 17.0 2.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGE08383.1 - 0.00099 18.9 2.5 5.9 6.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE08383.1 - 0.0066 15.9 3.5 0.024 14.0 3.5 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 EGE08383.1 - 0.01 15.6 0.1 11 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE08383.1 - 0.011 16.3 5.1 0.088 13.3 3.5 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE08383.1 - 0.012 16.2 4.6 0.76 10.6 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGE08383.1 - 0.11 12.6 2.7 22 5.4 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08383.1 - 3.4 8.7 9.2 2.2 9.3 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat APH PF01636.23 EGE08385.1 - 6.9e-15 55.6 0.2 9.4e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE08385.1 - 4.2e-05 23.2 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ank_2 PF12796.7 EGE08386.1 - 3.5e-112 367.2 6.2 1.1e-18 67.6 0.0 7.8 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08386.1 - 2.1e-89 292.8 0.2 6.5e-13 48.9 0.0 8.7 5 3 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08386.1 - 9.7e-83 262.2 0.1 6.4e-05 23.0 0.0 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank PF00023.30 EGE08386.1 - 8.8e-79 256.8 4.4 1.8e-06 28.1 0.0 13.4 13 0 0 13 13 13 13 Ankyrin repeat Ank_5 PF13857.6 EGE08386.1 - 9.6e-57 188.3 0.3 5.5e-08 32.9 0.0 10.0 4 3 8 12 12 12 11 Ankyrin repeats (many copies) F-box-like PF12937.7 EGE08386.1 - 7.2e-06 25.8 0.1 1.3e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like His_Me_b4a2 PF18275.1 EGE08386.1 - 9.2e-06 25.6 0.0 69 3.6 0.0 6.6 6 0 0 6 6 6 0 His-Me finger endonuclease beta4-alpha2 domain GATase_7 PF13537.6 EGE08386.1 - 0.00077 19.4 0.0 18 5.3 0.0 5.9 5 2 3 8 8 8 0 Glutamine amidotransferase domain TPR_20 PF14561.6 EGE08386.1 - 0.0055 17.0 0.1 1.3 9.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat UPF0172 PF03665.13 EGE08386.1 - 0.016 15.2 1.0 18 5.3 0.0 4.4 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0172) VWA_3_C PF18571.1 EGE08386.1 - 0.32 10.9 10.4 1.6 8.7 0.0 5.5 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Integrase_H2C2 PF17921.1 EGE08388.1 - 2e-19 69.4 0.0 4.1e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGE08388.1 - 2e-10 40.9 0.0 4.6e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 EGE08388.1 - 3.3e-05 24.0 0.1 0.0001 22.4 0.1 1.9 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 EGE08389.1 - 1.5e-17 63.9 0.3 2e-17 63.4 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.23 EGE08390.1 - 5.6e-12 46.1 0.0 1.1e-11 45.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE08390.1 - 0.0051 16.4 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase CCCAP PF15964.5 EGE08392.1 - 0.05 11.9 0.0 0.062 11.6 0.0 1.0 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family DUF468 PF04318.12 EGE08393.1 - 0.097 13.4 0.0 0.18 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF468) APG9 PF04109.16 EGE08396.1 - 7.8e-208 691.3 11.8 9.3e-208 691.1 11.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 EGE08397.1 - 2.4e-183 610.2 0.0 2.9e-183 610.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APH PF01636.23 EGE08400.1 - 3.2e-12 46.9 0.0 6.1e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE08400.1 - 6.5e-06 25.3 0.1 0.0095 14.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EGE08400.1 - 0.00085 18.7 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Vac14_Fab1_bd PF12755.7 EGE08401.1 - 3.9e-44 149.2 0.2 2.8e-40 136.8 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.8 EGE08401.1 - 4.3e-28 98.2 10.6 5e-15 55.6 0.2 3.9 2 1 2 4 4 4 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT_EZ PF13513.6 EGE08401.1 - 1.5e-08 35.0 1.9 0.12 12.9 0.0 5.5 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EGE08401.1 - 2.7e-06 27.2 0.2 0.39 11.1 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EGE08401.1 - 0.0042 17.2 0.9 1.2 9.2 0.0 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGE08401.1 - 0.0093 15.1 0.0 11 5.0 0.0 3.9 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Arm PF00514.23 EGE08401.1 - 0.12 12.5 0.0 44 4.3 0.0 4.5 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 EGE08402.1 - 3.1e-57 193.9 0.0 5.1e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EGE08402.1 - 3.3e-57 193.6 0.3 6.6e-57 192.6 0.3 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EGE08402.1 - 4.6e-15 55.9 0.0 1.5e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE08402.1 - 5.8e-09 36.2 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EGE08402.1 - 0.00024 20.4 0.0 0.0011 18.2 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Mito_carr PF00153.27 EGE08403.1 - 9.2e-39 131.3 3.1 4.8e-14 52.0 0.3 3.7 2 2 1 3 3 3 3 Mitochondrial carrier protein zf-C2H2_jaz PF12171.8 EGE08404.1 - 3.3e-10 40.0 4.1 3.3e-10 40.0 4.1 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGE08404.1 - 0.012 15.9 0.7 0.017 15.4 0.7 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGE08404.1 - 0.068 13.2 1.8 0.068 13.2 1.8 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 EGE08404.1 - 0.088 12.6 1.2 0.11 12.2 0.3 1.7 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_4 PF13894.6 EGE08404.1 - 0.096 13.6 0.8 0.096 13.6 0.8 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EGE08404.1 - 0.92 10.0 6.8 0.21 12.1 1.9 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.20 EGE08405.1 - 9.4e-136 453.5 0.0 1.6e-86 291.2 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGE08405.1 - 2.5e-43 147.5 0.0 4.3e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain BLACT_WH PF17778.1 EGE08406.1 - 6.1e-18 64.5 0.1 1.1e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EGE08406.1 - 8.9e-17 61.7 2.2 1e-15 58.3 2.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGE08406.1 - 1.9e-06 27.6 0.7 3.6e-06 26.6 0.6 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGE08406.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain YmzC PF14157.6 EGE08406.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 YmzC-like protein DUF1450 PF07293.11 EGE08406.1 - 0.17 11.7 0.0 5.7 6.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1450) Glyco_transf_20 PF00982.21 EGE08407.1 - 6.3e-200 664.8 0.0 7.2e-200 664.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EGE08407.1 - 0.015 15.0 0.2 0.039 13.6 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain UbiA PF01040.18 EGE08408.1 - 5.3e-18 65.2 1.9 6.1e-18 65.0 1.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Wzy_C_2 PF11846.8 EGE08408.1 - 0.02 14.8 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Prenyltransf PF01255.19 EGE08409.1 - 1.3e-67 227.7 0.0 1.6e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF2600 PF10776.9 EGE08409.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) PnpCD_PnpD_N PF18191.1 EGE08409.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal Porin_10 PF14121.6 EGE08409.1 - 0.25 9.9 0.5 0.37 9.3 0.1 1.3 1 1 0 1 1 1 0 Putative porin Nucleos_tra2_C PF07662.13 EGE08411.1 - 8.3e-73 244.6 1.0 8.3e-73 244.6 1.0 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EGE08411.1 - 9.2e-23 80.6 4.7 9.2e-23 80.6 4.7 3.0 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus FA_desaturase PF00487.24 EGE08411.1 - 0.043 13.7 0.0 0.043 13.7 0.0 3.0 3 1 0 3 3 3 0 Fatty acid desaturase DUF1180 PF06679.12 EGE08411.1 - 0.48 10.8 0.0 0.48 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) UQ_con PF00179.26 EGE08413.1 - 7.1e-49 165.1 0.0 8.5e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGE08413.1 - 0.0001 22.5 0.0 0.00017 21.9 0.0 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGE08413.1 - 0.0043 16.8 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGE08413.1 - 0.0059 16.5 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain UFC1 PF08694.11 EGE08413.1 - 0.11 12.1 0.0 0.66 9.6 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 EGE08414.1 - 5.1e-61 206.3 0.0 1.7e-60 204.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08414.1 - 2.6e-26 92.5 0.0 3.7e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE08414.1 - 6.7e-10 38.7 0.0 9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGE08414.1 - 0.0033 16.8 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box PF00646.33 EGE08415.1 - 1.5e-08 34.3 1.1 2.8e-08 33.4 1.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGE08415.1 - 2.3e-06 27.4 2.5 4.4e-06 26.5 2.5 1.5 1 0 0 1 1 1 1 F-box-like DHBP_synthase PF00926.19 EGE08416.1 - 1.9e-80 268.9 0.0 2.2e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.15 EGE08417.1 - 1e-22 80.2 0.1 1.2e-21 76.8 0.0 2.5 2 1 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EGE08417.1 - 4.3e-22 77.6 1.5 6.9e-22 76.9 0.3 2.0 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 DUF1631 PF07793.11 EGE08417.1 - 0.18 10.2 4.3 0.031 12.7 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) TPR_MLP1_2 PF07926.12 EGE08418.1 - 2.4e-37 127.9 30.5 2.4e-37 127.9 30.5 17.4 5 5 10 18 18 18 7 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EGE08418.1 - 0.0011 19.0 4.4 0.0011 19.0 4.4 13.0 9 5 5 14 14 14 4 Baculovirus polyhedron envelope protein, PEP, C terminus CotJB PF12652.7 EGE08418.1 - 0.03 14.5 1.1 14 6.0 0.1 4.6 2 0 0 2 2 2 0 CotJB protein Cbl_N PF02262.16 EGE08418.1 - 0.049 13.6 3.9 0.95 9.5 0.2 4.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Hexapep PF00132.24 EGE08419.1 - 1.9e-08 33.7 8.1 0.0013 18.3 3.3 4.2 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGE08419.1 - 5.7e-05 22.8 4.2 0.0099 15.6 1.9 3.4 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.7 EGE08420.1 - 3.3e-69 232.0 0.0 3.8e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD PF12710.7 EGE08420.1 - 0.17 12.3 0.7 5.4 7.4 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 EGE08421.1 - 0.00021 21.6 2.3 0.00095 19.5 1.2 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGE08421.1 - 0.04 14.0 5.4 31 5.0 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 EGE08421.1 - 0.041 13.6 1.0 0.57 10.0 0.8 2.6 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 EGE08421.1 - 0.17 12.5 0.4 1.1e+02 4.0 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Sec63 PF02889.16 EGE08422.1 - 4.8e-35 121.0 0.0 7.2e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EGE08422.1 - 1.9e-27 96.1 0.1 5e-27 94.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGE08422.1 - 1.5e-14 54.4 0.0 3.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGE08422.1 - 2.9e-08 34.0 0.0 1.3e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGE08422.1 - 0.0003 21.1 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGE08422.1 - 0.0014 19.0 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGE08422.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGE08422.1 - 0.036 14.5 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 EGE08422.1 - 0.076 12.9 0.1 0.81 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase Nuc_sug_transp PF04142.15 EGE08423.1 - 1.3e-87 294.0 9.2 1.7e-87 293.6 9.2 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGE08423.1 - 0.0068 16.6 9.9 0.0068 16.6 9.9 2.8 2 2 0 2 2 2 1 EamA-like transporter family HORMA PF02301.18 EGE08426.1 - 1e-70 237.6 0.0 2e-70 236.7 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 EGE08426.1 - 0.0018 18.1 8.5 0.004 17.0 8.5 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGE08426.1 - 0.062 12.9 2.8 0.16 11.5 2.8 1.7 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 EGE08428.1 - 1.2e-40 136.7 16.7 3.4e-06 27.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGE08428.1 - 2.3e-10 40.2 0.1 5.2e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE08428.1 - 3e-10 39.7 0.2 6e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGE08428.1 - 3.7e-05 23.9 1.2 8.3 6.8 0.0 4.6 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE08428.1 - 8.2e-05 21.4 3.3 4.9 5.7 0.2 5.2 4 2 1 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 EGE08428.1 - 0.002 18.0 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 F-box Vert_IL3-reg_TF PF06529.11 EGE08428.1 - 0.025 13.7 0.1 0.044 12.9 0.1 1.3 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor FliG_C PF01706.16 EGE08428.1 - 0.096 12.9 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 FliG C-terminal domain AcylCoA_DH_N PF12418.8 EGE08428.1 - 0.16 12.0 0.2 0.49 10.5 0.2 1.9 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal MMR_HSR1 PF01926.23 EGE08429.1 - 1.6e-15 57.2 0.0 3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGE08429.1 - 9.5e-06 25.8 0.0 0.00029 20.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 EGE08429.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EGE08429.1 - 2.6e-05 23.9 0.1 0.013 15.0 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGE08429.1 - 3.9e-05 23.6 0.6 0.0011 18.9 0.2 2.3 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EGE08429.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EGE08429.1 - 0.0085 15.4 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 EGE08429.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGE08429.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGE08429.1 - 0.17 11.3 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Clat_adaptor_s PF01217.20 EGE08430.1 - 3.4e-42 143.7 0.0 5.4e-42 143.1 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 EGE08432.1 - 3.5e-21 74.7 0.3 6e-21 74.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRP36 PF06102.12 EGE08432.1 - 0.012 15.6 0.5 0.012 15.6 0.5 2.1 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 Cnd1 PF12717.7 EGE08433.1 - 3.7e-07 30.3 0.0 0.052 13.6 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGE08433.1 - 1.9e-06 27.6 0.0 0.0021 17.7 0.0 2.3 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EGE08433.1 - 2.8e-06 27.1 0.5 0.89 10.0 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EGE08433.1 - 2e-05 24.9 0.1 0.011 16.1 0.1 3.9 2 1 2 4 4 4 1 HEAT repeats Adaptin_N PF01602.20 EGE08433.1 - 0.00013 20.7 0.5 0.00088 18.0 0.5 2.4 1 1 0 1 1 1 1 Adaptin N terminal region TAN PF11640.8 EGE08433.1 - 0.001 19.2 0.1 0.011 15.9 0.0 2.5 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 EGE08433.1 - 0.036 14.6 0.4 1.3 9.6 0.2 3.3 3 0 0 3 3 3 0 HEAT-like repeat DCB PF16213.5 EGE08433.1 - 0.05 13.3 0.1 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Proteasom_PSMB PF10508.9 EGE08433.1 - 0.054 12.0 0.1 7.6 4.9 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit G-gamma PF00631.22 EGE08433.1 - 0.15 12.1 0.9 0.48 10.5 0.9 1.9 1 0 0 1 1 1 0 GGL domain Pkinase PF00069.25 EGE08434.1 - 2.7e-08 33.5 0.0 3.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08434.1 - 2.7e-07 30.2 0.0 1.4e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGE08434.1 - 0.011 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE08434.1 - 0.09 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EGE08434.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1720 PF08226.11 EGE08435.1 - 4.7e-08 33.3 37.3 4.7e-08 33.3 37.3 5.5 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) Chorismate_bind PF00425.18 EGE08436.1 - 6.7e-92 307.7 0.0 8.9e-92 307.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EGE08436.1 - 3.1e-28 98.8 0.0 1.7e-24 86.6 0.0 3.9 3 1 1 4 4 4 2 Anthranilate synthase component I, N terminal region AATF-Che1 PF13339.6 EGE08437.1 - 0.1 13.3 1.0 0.49 11.1 0.3 2.2 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor ANAPC4_WD40 PF12894.7 EGE08438.1 - 3e-07 30.6 0.1 0.0012 19.1 0.0 4.8 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGE08438.1 - 7.9e-07 29.7 1.6 6.2 7.9 0.0 5.8 7 1 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.11 EGE08438.1 - 0.093 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EGE08438.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 LisH PD40 PF07676.12 EGE08438.1 - 2.7 8.0 7.0 55 3.9 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1751 PF08551.10 EGE08439.1 - 4.8e-29 100.9 0.5 1e-28 99.8 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGE08439.1 - 0.00012 22.1 10.4 0.00031 20.8 10.4 1.6 1 0 0 1 1 1 1 Rhomboid family L51_S25_CI-B8 PF05047.16 EGE08440.1 - 2.8e-13 49.5 0.0 5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LRS4 PF10422.9 EGE08440.1 - 0.25 10.9 3.0 0.35 10.4 3.0 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 tRNA-synt_1 PF00133.22 EGE08441.1 - 1.7e-34 119.0 0.0 1.7e-24 86.1 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGE08441.1 - 2.1e-15 56.4 0.0 3.7e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGE08441.1 - 1.9e-11 44.1 0.0 5.5e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGE08441.1 - 4.2e-07 29.6 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGE08441.1 - 0.02 13.8 0.0 0.15 10.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Mito_carr PF00153.27 EGE08442.1 - 1.8e-65 216.9 6.3 5.6e-22 77.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.6 EGE08442.1 - 0.11 12.1 0.0 0.83 9.3 0.0 2.0 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a Serine_protease PF18405.1 EGE08442.1 - 0.21 10.7 2.8 1.3 8.1 0.2 3.0 2 1 1 3 3 3 0 Gammaproteobacterial serine protease IBR PF01485.21 EGE08443.1 - 8.5e-23 80.4 48.8 7.5e-13 48.5 5.7 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGE08443.1 - 0.00089 19.5 8.7 0.00089 19.5 8.7 4.0 3 1 1 4 4 4 2 Ring finger domain UN_NPL4 PF11543.8 EGE08443.1 - 0.0011 19.4 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-C3HC4 PF00097.25 EGE08443.1 - 0.0016 18.3 5.4 0.0016 18.3 5.4 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE08443.1 - 0.0063 16.3 5.6 0.0063 16.3 5.6 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGE08443.1 - 0.012 15.5 9.6 0.012 15.5 9.6 3.1 3 0 0 3 3 3 0 zinc-RING finger domain W2 PF02020.18 EGE08444.1 - 1.8e-18 66.4 1.9 1.8e-18 66.4 1.9 3.1 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGE08444.1 - 6.6e-12 44.7 12.6 0.00063 19.4 2.2 3.5 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EGE08444.1 - 6.2e-05 22.7 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EGE08444.1 - 0.00016 21.3 7.1 0.0053 16.5 1.4 2.8 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGE08444.1 - 0.023 12.8 1.8 0.04 12.0 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Antifungal_pept PF11410.8 EGE08445.1 - 0.097 12.6 13.8 0.16 11.9 1.0 3.4 3 1 0 3 3 3 0 Antifungal peptide Tryp_inh PF17983.1 EGE08445.1 - 3.5 7.8 15.1 0.28 11.3 3.6 2.8 2 1 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Methyltransf_33 PF10017.9 EGE08446.1 - 1.2e-86 290.6 0.0 1.8e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EGE08446.1 - 1.5e-11 44.4 4.9 3.8e-10 39.8 4.9 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EGE08446.1 - 9.3e-07 29.4 1.6 5.1e-06 27.0 1.0 2.4 2 0 0 2 2 2 1 DinB superfamily GAD-like PF08887.11 EGE08446.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 GAD-like domain TPR_2 PF07719.17 EGE08447.1 - 7.6e-05 22.5 0.0 0.023 14.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF1635 PF07795.11 EGE08447.1 - 0.026 14.4 0.1 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DUF92 PF01940.16 EGE08449.1 - 5.2e-75 251.9 7.0 6.1e-75 251.7 7.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 MFS_1 PF07690.16 EGE08450.1 - 1.5e-22 80.1 30.6 8.9e-18 64.3 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08450.1 - 3.2e-07 29.6 0.8 3.2e-07 29.6 0.8 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGE08450.1 - 7.2e-06 25.5 2.2 7.2e-06 25.5 2.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 EGE08450.1 - 0.00066 18.0 0.1 0.0014 16.9 0.1 1.5 1 0 0 1 1 1 1 BT1 family NADH-u_ox-rdase PF10785.9 EGE08450.1 - 0.055 14.2 0.8 1.7 9.4 0.4 3.0 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit WD40 PF00400.32 EGE08451.1 - 8.5e-06 26.4 0.7 0.43 11.5 0.0 5.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF676 PF05057.14 EGE08451.1 - 3.2e-05 23.5 0.0 0.00013 21.5 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGE08451.1 - 0.0044 16.8 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGE08451.1 - 0.0094 16.6 0.0 0.025 15.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fructosamin_kin PF03881.14 EGE08452.1 - 1.1e-29 103.6 0.0 1.4e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EGE08452.1 - 0.086 12.7 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Radical_SAM PF04055.21 EGE08453.1 - 7.6e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGE08453.1 - 0.00016 22.0 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGE08453.1 - 0.026 14.6 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain T2SSI PF02501.17 EGE08454.1 - 0.15 12.2 2.4 0.27 11.4 2.4 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein I Apis_Csd PF11671.8 EGE08455.1 - 0.0056 16.7 4.7 0.0077 16.3 4.7 1.1 1 0 0 1 1 1 1 Complementary sex determiner protein RNA_pol PF00940.19 EGE08457.1 - 9.6e-184 611.0 0.0 1.4e-183 610.4 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGE08457.1 - 1.4e-91 307.4 0.6 2.1e-91 306.8 0.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 EGE08458.1 - 1.7e-27 96.7 0.5 6.7e-27 94.8 0.5 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region ATP-synt_S1 PF05827.12 EGE08460.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 EGE08461.1 - 1.5e-38 132.4 10.6 1.5e-38 132.4 10.6 3.1 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) EIIBC-GUT_N PF03612.14 EGE08461.1 - 0.19 11.4 10.6 0.14 11.9 1.0 2.5 2 1 1 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Tropomyosin_1 PF12718.7 EGE08462.1 - 6.3e-50 169.1 34.7 7.8e-50 168.8 34.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EGE08462.1 - 8.6e-10 38.4 35.5 4e-06 26.4 16.2 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 EGE08462.1 - 0.00014 22.0 24.6 0.0003 21.0 10.3 3.3 1 1 1 3 3 3 2 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 EGE08462.1 - 0.00022 20.2 34.1 0.091 11.6 18.1 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 EGE08462.1 - 0.0011 18.4 33.5 0.0086 15.5 26.6 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EGE08462.1 - 0.0018 18.3 18.7 0.0073 16.3 4.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EGE08462.1 - 0.0023 18.0 6.2 0.0023 18.0 6.2 3.1 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EGE08462.1 - 0.01 16.1 32.7 0.34 11.1 24.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EGE08462.1 - 0.011 15.8 16.7 0.011 15.8 16.7 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 EGE08462.1 - 0.012 15.6 8.4 0.012 15.6 8.4 2.1 1 1 1 2 2 2 0 Laminin Domain II Med9 PF07544.13 EGE08462.1 - 0.013 15.5 6.1 0.013 15.5 6.1 3.2 1 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 EGE08462.1 - 0.025 14.7 33.2 0.42 10.7 10.5 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding MAD PF05557.13 EGE08462.1 - 0.025 13.0 31.8 0.035 12.5 31.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein CEP63 PF17045.5 EGE08462.1 - 0.16 11.8 29.3 1.1 9.0 29.3 1.9 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa DUF4200 PF13863.6 EGE08462.1 - 0.18 12.2 35.0 0.21 12.0 15.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) ERM PF00769.19 EGE08462.1 - 0.22 11.3 39.9 0.18 11.6 19.7 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 EGE08462.1 - 0.27 11.0 28.9 0.12 12.2 10.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SesA PF17107.5 EGE08462.1 - 0.38 10.9 10.2 0.17 12.1 6.8 2.1 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BLOC1_2 PF10046.9 EGE08462.1 - 0.41 11.0 24.2 1.3 9.4 1.0 3.4 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EGE08462.1 - 0.41 11.1 22.3 0.62 10.5 0.3 4.3 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 EGE08462.1 - 0.55 10.4 35.3 0.079 13.2 23.7 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Laminin_I PF06008.14 EGE08462.1 - 0.58 9.8 27.2 93 2.6 27.2 2.7 1 1 0 1 1 1 0 Laminin Domain I SlyX PF04102.12 EGE08462.1 - 0.75 10.5 26.9 1.8 9.2 1.7 3.5 1 1 2 3 3 3 0 SlyX CLZ PF16526.5 EGE08462.1 - 0.85 10.0 24.8 0.31 11.4 2.8 3.3 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Atg14 PF10186.9 EGE08462.1 - 1.1 8.2 27.9 3.7 6.5 11.9 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 EGE08462.1 - 1.3 7.6 27.7 4.8 5.7 27.7 2.0 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EGE08462.1 - 1.3 6.5 29.6 1.8 6.0 29.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 EGE08462.1 - 1.6 8.0 31.1 0.44 9.8 12.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BST2 PF16716.5 EGE08462.1 - 2.2 8.9 29.4 2.1 9.0 11.5 3.3 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Cep57_MT_bd PF06657.13 EGE08462.1 - 2.3 8.7 23.5 0.054 13.9 3.8 3.7 2 1 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 EGE08462.1 - 2.7 8.4 30.2 3.2 8.2 26.9 1.9 1 1 1 2 2 2 0 Fez1 JIP_LZII PF16471.5 EGE08462.1 - 2.8 8.2 27.3 0.29 11.4 5.4 4.0 2 1 1 4 4 4 0 JNK-interacting protein leucine zipper II KxDL PF10241.9 EGE08462.1 - 3 8.2 22.5 0.39 11.0 1.2 4.0 1 1 3 4 4 4 0 Uncharacterized conserved protein KELK PF15796.5 EGE08462.1 - 3.2 8.3 33.8 16 6.0 15.2 3.6 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF16 PF01519.16 EGE08462.1 - 3.4 8.2 24.1 17 6.0 5.2 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 FUSC PF04632.12 EGE08462.1 - 3.7 6.0 9.1 4.2 5.8 9.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 EGE08462.1 - 3.8 7.8 12.9 10 6.5 4.5 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 EGE08462.1 - 4.3 7.4 33.4 13 5.8 13.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 EGE08462.1 - 4.6 6.8 29.3 9.1 5.9 23.3 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PspB PF06667.12 EGE08462.1 - 5 7.3 18.7 0.73 9.9 4.7 3.7 1 1 2 3 3 3 0 Phage shock protein B Fmp27_SW PF10305.9 EGE08462.1 - 5.2 7.8 7.9 0.52 11.1 1.3 2.3 1 1 2 3 3 3 0 RNA pol II promoter Fmp27 protein domain MS_channel PF00924.18 EGE08462.1 - 6 6.3 5.0 9.7 5.7 5.0 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel TMF_DNA_bd PF12329.8 EGE08462.1 - 6.3 6.9 37.5 0.67 10.0 14.4 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 EGE08462.1 - 6.8 7.0 27.0 6.2 7.1 1.7 4.2 1 1 3 4 4 4 0 Haemolysin XhlA YabA PF06156.13 EGE08462.1 - 7.3 7.3 26.5 1.8e+04 -6.3 26.2 3.1 1 1 0 1 1 0 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EGE08462.1 - 7.4 6.8 33.6 36 4.6 15.0 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EGE08462.1 - 7.8 7.0 40.5 18 5.8 16.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EGE08462.1 - 8 6.7 27.2 2.4 8.3 0.7 4.4 2 1 2 4 4 4 0 bZIP transcription factor Dicty_REP PF05086.12 EGE08463.1 - 0.42 8.5 6.1 0.57 8.1 6.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CMAS PF02353.20 EGE08464.1 - 2.8e-24 85.9 0.0 3.2e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGE08464.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 EGE08465.1 - 3.9e-92 309.0 0.0 4.7e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE08465.1 - 9.1e-17 61.8 0.1 4.4e-16 59.6 0.0 2.2 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain SNF2_N PF00176.23 EGE08466.1 - 0.00068 18.5 0.0 0.00077 18.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain MFS_1 PF07690.16 EGE08469.1 - 2.2e-39 135.4 31.6 2.4e-33 115.5 24.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGE08469.1 - 9.7e-07 28.4 13.7 2.5e-05 23.7 3.6 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGE08469.1 - 4.6e-05 21.9 13.0 0.00016 20.2 8.3 3.2 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGE08469.1 - 0.0026 16.7 14.9 0.07 12.0 10.2 2.2 2 0 0 2 2 2 2 MFS_1 like family Mucin15 PF15672.5 EGE08469.1 - 0.19 11.2 3.0 4.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 MCM PF00493.23 EGE08471.1 - 6.6e-103 342.6 0.0 1.1e-102 342.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGE08471.1 - 2e-31 108.5 0.1 3.5e-31 107.7 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGE08471.1 - 1e-21 77.1 0.7 2.8e-21 75.7 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGE08471.1 - 5.8e-18 65.4 0.2 1.7e-17 63.9 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGE08471.1 - 3.2e-07 29.9 0.0 4.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE08471.1 - 2.2e-05 24.5 0.0 5.6e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 EGE08471.1 - 0.031 14.9 0.1 0.13 12.9 0.1 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 EGE08471.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EGE08471.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA-ATPase_like PF09820.9 EGE08471.1 - 0.11 11.9 0.3 0.27 10.6 0.3 1.6 1 1 0 1 1 1 0 Predicted AAA-ATPase AAA PF00004.29 EGE08472.1 - 1.5e-54 183.9 0.0 2.9e-43 147.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EGE08472.1 - 2.1e-30 104.9 0.6 4.8e-30 103.8 0.6 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EGE08472.1 - 8e-15 54.4 0.1 3e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGE08472.1 - 2e-08 34.8 3.2 0.0049 17.3 0.1 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EGE08472.1 - 9e-07 29.2 0.0 0.053 13.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EGE08472.1 - 1e-06 28.8 0.4 0.00067 19.6 0.0 3.4 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 EGE08472.1 - 1.6e-05 24.7 0.0 0.022 14.5 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EGE08472.1 - 6.4e-05 23.0 0.1 0.12 12.3 0.0 2.8 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGE08472.1 - 9.9e-05 22.1 0.0 0.071 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 EGE08472.1 - 0.00014 22.2 1.0 1.4 9.2 0.1 3.7 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGE08472.1 - 0.00068 19.6 0.0 1.9 8.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGE08472.1 - 0.00077 19.5 0.0 0.81 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGE08472.1 - 0.0019 18.7 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGE08472.1 - 0.0032 16.8 0.0 0.72 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 EGE08472.1 - 0.0033 16.7 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EGE08472.1 - 0.0034 17.5 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGE08472.1 - 0.0036 16.9 0.3 5.8 6.4 0.2 3.1 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGE08472.1 - 0.0097 16.3 0.0 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EGE08472.1 - 0.017 15.4 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGE08472.1 - 0.02 14.3 0.5 1 8.7 0.1 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EGE08472.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EGE08472.1 - 0.03 14.8 0.0 5.7 7.5 0.1 2.7 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 EGE08472.1 - 0.05 12.8 0.1 0.39 9.9 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 EGE08472.1 - 0.067 12.7 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EGE08472.1 - 0.068 12.9 0.2 0.34 10.6 0.0 2.3 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EGE08472.1 - 0.087 12.2 0.1 15 4.9 0.0 2.5 2 0 0 2 2 2 0 KaiC APS_kinase PF01583.20 EGE08472.1 - 0.15 11.9 0.1 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.26 EGE08472.1 - 0.19 11.4 0.0 7.8 6.2 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 EGE08472.1 - 0.31 11.4 2.3 2.7 8.4 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF1840 PF08895.11 EGE08472.1 - 0.36 11.2 1.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) HisG PF01634.18 EGE08473.1 - 4.5e-41 140.5 0.2 5e-30 104.6 0.0 2.2 1 1 1 2 2 2 2 ATP phosphoribosyltransferase HisG_C PF08029.11 EGE08473.1 - 5e-29 100.2 0.2 9.8e-29 99.3 0.2 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EGE08473.1 - 0.029 14.3 0.1 8.1 6.3 0.0 2.3 1 1 1 2 2 2 0 NMT1/THI5 like Ribosomal_S28e PF01200.18 EGE08474.1 - 4.4e-33 113.1 0.4 4.9e-33 112.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.21 EGE08475.1 - 2.4e-73 246.2 0.1 4.6e-73 245.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGE08475.1 - 1.3e-33 116.9 0.6 1.3e-33 116.9 0.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGE08475.1 - 8.2e-29 100.1 0.1 1.7e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGE08475.1 - 5.3e-10 39.7 0.0 3.1e-09 37.2 0.0 2.4 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGE08475.1 - 1.1e-05 25.7 0.2 2.8e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV LpxB PF02684.15 EGE08475.1 - 0.051 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase NOA36 PF06524.12 EGE08475.1 - 3.8 6.7 12.3 7.1 5.9 12.3 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EGE08475.1 - 9.5 4.4 13.7 15 3.7 13.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Prenyltrans PF00432.21 EGE08477.1 - 8.5e-59 195.0 5.0 3.4e-11 42.7 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EGE08477.1 - 9.2e-08 31.5 0.0 0.0076 15.4 0.0 4.2 2 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EGE08477.1 - 0.00037 19.7 1.0 0.03 13.4 0.1 3.0 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain RhoGAP PF00620.27 EGE08480.1 - 5.8e-07 29.5 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DAP3 PF10236.9 EGE08481.1 - 6.3e-67 225.9 0.0 1e-66 225.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AdoMetDC_leader PF08132.11 EGE08481.1 - 0.047 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide DUF2075 PF09848.9 EGE08481.1 - 0.065 12.5 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGE08481.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein tRNA-synt_1d PF00750.19 EGE08484.1 - 2.9e-92 309.3 0.4 5.1e-92 308.5 0.4 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGE08484.1 - 8.3e-19 67.9 0.3 4.5e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGE08484.1 - 0.011 16.2 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain PrpF PF04303.13 EGE08485.1 - 1.3e-106 356.7 0.2 1.5e-106 356.5 0.2 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.19 EGE08486.1 - 1.6e-13 51.0 0.7 6.8e-13 49.0 0.8 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Alg14 PF08660.11 EGE08486.1 - 0.0043 17.0 0.4 0.01 15.8 0.4 1.6 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RhoGEF PF00621.20 EGE08487.1 - 1.2e-35 123.4 0.0 1.2e-35 123.4 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain Lipoprotein_7 PF01540.16 EGE08487.1 - 0.49 9.6 1.6 9.6 5.4 0.0 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein RVT_1 PF00078.27 EGE08488.1 - 1e-07 31.7 0.0 3.4e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) 2Fe-2S_thioredx PF01257.19 EGE08488.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RabGAP-TBC PF00566.18 EGE08489.1 - 7.1e-28 97.7 0.0 1.5e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EGE08489.1 - 7.1e-07 27.9 0.3 7.1e-07 27.9 0.3 1.7 2 0 0 2 2 2 1 SBE2, cell-wall formation Proteasome PF00227.26 EGE08490.1 - 1.8e-45 154.7 0.3 2.1e-45 154.6 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 EGE08491.1 - 3.4e-15 56.8 0.2 4.2e-13 50.0 0.0 4.4 2 1 2 4 4 4 2 Cyclin DUF3484 PF11983.8 EGE08491.1 - 1.1 10.4 0.0 1.1 10.4 0.0 3.3 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch FAM60A PF15396.6 EGE08491.1 - 2.8 7.9 9.9 9 6.2 2.5 2.5 2 0 0 2 2 2 0 Protein Family FAM60A WBP-1 PF11669.8 EGE08491.1 - 3.1 8.5 5.3 55 4.5 0.0 2.9 2 1 0 2 2 2 0 WW domain-binding protein 1 Neur_chan_memb PF02932.16 EGE08491.1 - 5.3 7.0 11.0 8.7 6.3 0.5 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hydrolase_4 PF12146.8 EGE08492.1 - 5.2e-17 61.9 0.0 6.1e-13 48.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGE08492.1 - 2.6e-11 43.7 0.0 6e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE08492.1 - 8.4e-06 26.5 0.0 1.3e-05 25.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGE08492.1 - 3.3e-05 23.7 0.0 0.0001 22.0 0.0 1.7 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGE08492.1 - 4.3e-05 23.1 0.0 0.00066 19.2 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGE08492.1 - 5e-05 22.1 0.1 0.046 12.4 0.1 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EGE08492.1 - 0.00022 21.2 0.0 0.0081 16.1 0.0 2.3 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGE08492.1 - 0.0013 18.3 0.0 0.39 10.2 0.0 2.6 2 1 1 3 3 3 1 Dienelactone hydrolase family PGAP1 PF07819.13 EGE08492.1 - 0.0037 17.0 0.1 0.024 14.4 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EGE08492.1 - 0.0091 15.9 0.1 0.017 15.0 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EGE08492.1 - 0.042 12.8 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LIDHydrolase PF10230.9 EGE08492.1 - 0.067 12.7 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EGE08492.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 EGE08492.1 - 0.23 11.0 0.1 0.48 10.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Lipoprotein_10 PF03202.13 EGE08493.1 - 0.064 13.7 1.7 0.098 13.1 0.1 2.1 2 1 1 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region Cas9_C PF18525.1 EGE08493.1 - 0.067 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Cas9 C-terminal domain Thiamine_BP PF01910.17 EGE08497.1 - 4.3e-18 65.0 0.2 4.8e-18 64.9 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein TPR_8 PF13181.6 EGE08498.1 - 8.3e-06 25.6 0.2 0.051 13.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE08498.1 - 0.0019 18.5 1.7 16 5.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08498.1 - 0.012 16.4 4.8 3.1 8.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE08498.1 - 0.049 14.1 5.8 4.9 7.7 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08498.1 - 0.26 11.5 6.3 3.2 8.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGE08498.1 - 0.27 11.1 2.6 6.6 6.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.6 EGE08499.1 - 1.9e-26 92.8 0.2 3.3e-26 92.0 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EGE08499.1 - 1.2e-12 48.4 0.0 1.9e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGE08499.1 - 4.4e-08 33.2 0.0 3.2e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGE08499.1 - 1.7e-06 28.7 0.0 4.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 EGE08499.1 - 0.00016 21.6 4.0 0.00035 20.5 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGE08499.1 - 0.0015 18.8 4.8 0.0033 17.7 4.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGE08499.1 - 0.022 14.6 4.4 0.045 13.6 4.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE08499.1 - 0.025 14.4 4.2 0.059 13.2 4.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE08499.1 - 0.05 13.5 1.9 0.12 12.3 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGE08499.1 - 0.1 12.3 5.9 0.04 13.5 2.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGE08499.1 - 0.31 10.9 3.5 0.66 9.9 3.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 EGE08499.1 - 0.4 11.0 3.5 0.81 10.0 3.5 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EGE08499.1 - 1.1 9.4 4.9 3.7 7.7 4.9 2.0 1 1 0 1 1 1 0 Zinc-finger Ribosomal_L12 PF00542.19 EGE08500.1 - 6.1e-22 77.7 8.3 1.6e-20 73.2 6.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGE08500.1 - 9.9e-13 47.6 8.6 9.9e-13 47.6 8.6 3.4 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EGE08500.1 - 0.00094 19.7 4.1 0.00094 19.7 4.1 2.2 2 1 0 2 2 2 1 60s Acidic ribosomal protein SpoVIF PF14069.6 EGE08500.1 - 0.092 12.5 3.1 0.2 11.4 0.3 2.5 2 1 0 2 2 2 0 Stage VI sporulation protein F Cpn60_TCP1 PF00118.24 EGE08501.1 - 7.5e-147 489.9 6.0 8.5e-147 489.7 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GP24_25 PF17388.2 EGE08501.1 - 0.052 13.5 0.5 0.17 11.9 0.5 1.8 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 EAL PF00563.20 EGE08501.1 - 0.074 12.6 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 EAL domain PrpR_N PF06506.11 EGE08501.1 - 0.081 12.5 0.2 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Propionate catabolism activator NOA36 PF06524.12 EGE08501.1 - 1.3 8.3 3.6 2 7.6 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EGE08501.1 - 1.3 9.4 7.0 2.9 8.3 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EGE08501.1 - 2.1 6.4 4.8 3 5.8 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4632 PF15451.6 EGE08501.1 - 7.2 6.8 5.5 17 5.6 5.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) E1_dh PF00676.20 EGE08502.1 - 9.6e-113 376.1 0.2 1.2e-112 375.8 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGE08502.1 - 7.1e-05 22.2 0.1 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGE08502.1 - 0.031 14.1 2.0 0.065 13.0 2.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pex14_N PF04695.13 EGE08504.1 - 0.095 13.4 13.0 0.093 13.4 9.3 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.10 EGE08504.1 - 0.17 11.6 18.9 0.25 11.0 18.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 NPV_P10 PF05531.12 EGE08504.1 - 0.61 10.6 3.2 2.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ASD2 PF08687.11 EGE08504.1 - 2.1 7.9 11.4 0.59 9.6 6.6 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Abhydrolase_1 PF00561.20 EGE08505.1 - 2.9e-24 86.1 0.3 1e-17 64.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGE08505.1 - 4e-20 73.4 1.3 5e-20 73.0 1.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGE08505.1 - 1.7e-09 37.3 0.2 9.9e-09 34.8 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGE08505.1 - 4.7e-05 23.2 0.3 0.013 15.2 0.3 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EGE08505.1 - 0.00039 20.1 0.1 0.0021 17.7 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EGE08505.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 EGE08505.1 - 0.0091 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.11 EGE08505.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Palm_thioest PF02089.15 EGE08505.1 - 0.058 13.2 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydro_lipase PF04083.16 EGE08505.1 - 0.13 11.8 0.8 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.13 EGE08505.1 - 0.23 9.9 0.2 3.6 6.0 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II APH PF01636.23 EGE08506.1 - 1.8e-13 51.0 0.1 1.8e-12 47.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family T2SSK PF03934.13 EGE08506.1 - 0.12 11.7 0.2 0.34 10.3 0.2 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K AA_permease_2 PF13520.6 EGE08507.1 - 7e-64 216.2 42.9 9e-64 215.9 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE08507.1 - 5.2e-29 101.2 40.2 3e-28 98.6 29.1 2.1 2 0 0 2 2 2 2 Amino acid permease NAD_binding_1 PF00175.21 EGE08508.1 - 5.5e-08 33.4 0.0 6.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGE08508.1 - 0.00019 21.7 0.0 0.00058 20.2 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGE08508.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.19 EGE08509.1 - 6.3e-27 94.5 0.0 5e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.20 EGE08510.1 - 2.3e-113 379.7 0.2 2e-112 376.6 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGE08510.1 - 9.2e-24 84.2 0.0 2.3e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5068 PF16781.5 EGE08510.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) Peptidase_M22 PF00814.25 EGE08511.1 - 3.5e-62 210.6 0.0 4.8e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family SET PF00856.28 EGE08512.1 - 7.5e-12 46.0 0.1 1.5e-11 45.0 0.1 1.4 1 1 0 1 1 1 1 SET domain FAM178 PF14816.6 EGE08512.1 - 0.0079 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function, FAM178 EPL1 PF10513.9 EGE08513.1 - 2.1e-20 73.7 0.3 2.1e-20 73.7 0.3 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 EGE08514.1 - 2.8e-27 92.2 12.3 8.6e-08 31.2 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGE08514.1 - 1.3e-22 80.0 12.0 2e-13 50.6 1.2 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGE08514.1 - 4.1e-20 69.9 8.3 5.6e-05 22.8 0.1 4.6 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EGE08514.1 - 8.9e-18 62.9 10.6 1.9e-06 27.1 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGE08514.1 - 1.8e-14 53.3 8.4 6.5e-05 22.7 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGE08514.1 - 4.4e-06 27.0 0.0 0.009 16.3 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGE08514.1 - 6.8e-05 22.8 8.5 0.02 14.8 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGE08514.1 - 0.035 14.4 0.1 0.82 10.0 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain DUF5096 PF17019.5 EGE08516.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) DUF3849 PF12960.7 EGE08516.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Ribosomal_S9 PF00380.19 EGE08517.1 - 3.1e-38 131.0 0.7 6.4e-38 130.0 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EGE08518.1 - 1.2e-17 63.9 0.1 7.6e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EGE08518.1 - 1.5e-11 44.3 0.0 2.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE08518.1 - 3e-11 43.5 0.0 7.3e-11 42.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE08518.1 - 1.1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE08518.1 - 6e-08 32.6 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE08518.1 - 3.6e-05 23.9 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGE08518.1 - 0.0009 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EGE08519.1 - 2.5e-27 95.6 2.7 1.2e-26 93.3 2.7 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase AMPK1_CBM PF16561.5 EGE08523.1 - 7.7e-30 102.9 0.1 1.3e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGE08523.1 - 5.5e-25 87.4 3.6 7.6e-25 87.0 1.7 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Mannosyl_trans3 PF11051.8 EGE08525.1 - 1.4e-59 201.8 0.0 3e-33 115.3 0.0 2.3 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EGE08525.1 - 0.016 14.7 0.2 0.046 13.3 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 8 ABC1 PF03109.16 EGE08526.1 - 8.8e-34 116.2 0.0 2.2e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 EGE08527.1 - 1.6e-22 80.5 1.7 2.1e-22 80.1 1.7 1.2 1 0 0 1 1 1 1 UreF BRE1 PF08647.11 EGE08528.1 - 2.1e-25 88.6 14.5 2.1e-25 88.6 14.5 6.8 4 2 3 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EGE08528.1 - 6.3e-10 38.8 8.3 1.1e-09 37.9 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE08528.1 - 2.6e-09 36.8 8.5 5.1e-09 35.8 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE08528.1 - 9.6e-08 31.8 10.8 1.8e-07 30.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE08528.1 - 1e-07 31.8 6.4 2.2e-07 30.8 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGE08528.1 - 1.1e-07 32.0 9.1 2e-07 31.2 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGE08528.1 - 2e-07 30.8 8.6 3.6e-07 29.9 8.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGE08528.1 - 2.1e-06 27.6 11.2 3.9e-06 26.7 11.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF745 PF05335.13 EGE08528.1 - 0.00042 20.1 5.7 0.00042 20.1 5.7 5.6 3 2 3 6 6 5 1 Protein of unknown function (DUF745) zf-rbx1 PF12678.7 EGE08528.1 - 0.0015 18.8 5.1 0.0046 17.2 5.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGE08528.1 - 0.0017 18.5 7.0 0.0033 17.5 7.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGE08528.1 - 0.019 15.1 7.3 0.048 13.8 7.3 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EGE08528.1 - 0.02 15.0 6.1 0.043 13.9 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) GP41 PF00517.17 EGE08528.1 - 0.038 13.9 0.1 0.038 13.9 0.1 4.4 4 1 0 4 4 4 0 Retroviral envelope protein zf-RING_4 PF14570.6 EGE08528.1 - 0.063 13.1 7.7 0.51 10.2 8.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGE08528.1 - 0.56 10.1 6.0 1.3 8.9 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-UDP PF14569.6 EGE08528.1 - 0.76 9.9 4.6 1.9 8.7 4.6 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-H2C2_2 PF13465.6 EGE08528.1 - 0.96 10.0 3.4 3.7 8.1 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_6 PF14835.6 EGE08528.1 - 1 9.3 3.8 2 8.3 3.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 EGE08528.1 - 1.8 8.8 12.7 32 4.8 11.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger zf-C2HE PF16278.5 EGE08528.1 - 2.4 8.7 6.2 7.2 7.1 0.2 3.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger AAA_13 PF13166.6 EGE08528.1 - 3.4 6.2 68.7 0.64 8.6 18.4 4.0 1 1 1 4 4 4 0 AAA domain HALZ PF02183.18 EGE08528.1 - 3.6 7.9 30.8 4.7 7.5 0.5 6.6 6 0 0 6 6 6 0 Homeobox associated leucine zipper Myb_DNA-bind_4 PF13837.6 EGE08528.1 - 4.5 7.7 11.7 0.34 11.3 0.3 4.0 4 0 0 4 4 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGE08529.1 - 5.2e-28 96.8 0.1 5.2e-28 96.8 0.1 2.3 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGE08529.1 - 0.00032 20.8 0.6 0.00063 19.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain SARAF PF06682.12 EGE08530.1 - 8.9e-86 288.5 9.1 1.9e-84 284.2 9.1 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MMM1 PF10296.9 EGE08531.1 - 1.3e-134 448.5 0.0 1.5e-134 448.2 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 EGE08532.1 - 8.1e-48 162.6 0.2 9.5e-48 162.3 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGE08532.1 - 5.4e-09 35.6 0.1 8.6e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGE08532.1 - 3.8e-05 23.6 0.0 5.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGE08532.1 - 0.06 13.0 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Cupin GIDA PF01134.22 EGE08533.1 - 9.7e-155 515.5 0.0 2.2e-154 514.3 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGE08533.1 - 4.9e-65 219.6 0.0 6.5e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EGE08533.1 - 2.3e-06 27.2 0.5 3.3e-06 26.7 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE08533.1 - 5.1e-06 25.9 0.3 9.4e-06 25.1 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGE08533.1 - 0.00045 19.4 1.7 0.00091 18.4 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGE08533.1 - 0.019 14.3 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EGE08533.1 - 0.028 13.3 0.1 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EGE08533.1 - 0.036 12.8 0.6 0.38 9.4 0.3 2.3 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EGE08533.1 - 0.086 12.4 0.6 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3605 PF12239.8 EGE08534.1 - 8e-50 169.1 2.4 1e-49 168.8 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Phytochelatin_C PF09328.10 EGE08534.1 - 0.053 12.9 0.1 0.098 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) Sec1 PF00995.23 EGE08535.1 - 5.1e-135 451.9 0.1 5.9e-135 451.7 0.1 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.25 EGE08536.1 - 1.8e-33 115.7 0.0 2.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE08536.1 - 1.2e-24 87.2 0.0 1.6e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE08536.1 - 1.1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGE08536.1 - 4.1e-07 29.7 0.0 1.3e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGE08536.1 - 0.00064 18.9 0.0 0.00082 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGE08536.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGE08536.1 - 0.0018 18.2 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE08536.1 - 0.02 14.5 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EGE08536.1 - 0.091 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_8 PF13450.6 EGE08537.1 - 3.9e-15 55.8 0.3 4.6e-14 52.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGE08537.1 - 3.1e-09 36.9 0.0 2.1e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGE08537.1 - 3.3e-08 33.1 0.1 3.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGE08537.1 - 9.3e-08 31.8 0.0 6.9e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EGE08537.1 - 4.6e-06 26.0 0.2 8.3e-06 25.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGE08537.1 - 1.9e-05 24.0 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGE08537.1 - 2e-05 23.5 0.4 0.00016 20.5 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EGE08537.1 - 8.4e-05 23.1 0.2 0.24 12.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGE08537.1 - 0.0003 20.3 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGE08537.1 - 0.0011 19.0 0.4 0.021 14.8 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EGE08537.1 - 0.0021 17.0 0.1 0.007 15.3 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGE08537.1 - 0.0025 17.1 0.0 0.09 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE08537.1 - 0.02 14.1 0.1 0.067 12.4 0.1 1.9 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EGE08537.1 - 0.026 13.6 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EGE08537.1 - 0.07 12.2 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EGE08537.1 - 0.096 12.3 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 EGE08537.1 - 0.12 11.7 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase CAP_assoc_N PF14504.6 EGE08537.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 CAP-associated N-terminal Tyr-DNA_phospho PF06087.12 EGE08538.1 - 3.2e-56 191.0 0.0 4.2e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase DUF2722 PF10846.8 EGE08538.1 - 0.00084 18.4 6.8 0.0012 17.9 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF740 PF05340.12 EGE08538.1 - 0.0044 15.9 9.1 0.006 15.4 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF740) DUF5523 PF17661.1 EGE08538.1 - 0.011 15.4 16.5 1.5 8.5 14.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF2052 PF09747.9 EGE08538.1 - 0.017 15.3 16.6 0.028 14.5 16.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.14 EGE08538.1 - 0.064 13.0 10.8 0.14 12.0 10.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.12 EGE08538.1 - 0.081 11.5 19.0 0.11 11.1 19.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BSP_II PF05432.11 EGE08538.1 - 0.1 12.3 20.4 0.16 11.7 20.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FYDLN_acid PF09538.10 EGE08538.1 - 0.19 12.4 14.9 0.37 11.5 14.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.13 EGE08538.1 - 0.22 10.5 17.8 0.32 10.0 17.8 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 EGE08538.1 - 0.27 9.3 27.4 0.37 8.8 27.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF572 PF04502.13 EGE08538.1 - 0.35 10.4 10.8 0.5 9.9 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mpp10 PF04006.12 EGE08538.1 - 0.44 8.9 20.6 0.57 8.6 20.6 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EGE08538.1 - 0.47 9.7 19.8 0.66 9.2 19.8 1.2 1 0 0 1 1 1 0 BUD22 MRNIP PF15749.5 EGE08538.1 - 0.63 10.8 3.9 1.3 9.7 3.9 1.5 1 0 0 1 1 1 0 MRN-interacting protein NOA36 PF06524.12 EGE08538.1 - 1.2 8.4 20.0 1.6 8.0 20.0 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EGE08538.1 - 1.7 6.8 19.5 2.3 6.4 19.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 EGE08538.1 - 1.9 9.1 5.1 6.2 7.5 5.3 1.9 2 0 0 2 2 1 0 RPA43 OB domain in RNA Pol I TFB6 PF17110.5 EGE08538.1 - 2.1 8.0 8.7 3.8 7.2 8.7 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4746 PF15928.5 EGE08538.1 - 2.6 7.4 15.6 4 6.8 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RXT2_N PF08595.11 EGE08538.1 - 2.6 8.1 11.4 3.1 7.8 10.5 1.6 2 0 0 2 2 1 0 RXT2-like, N-terminal PI3K_1B_p101 PF10486.9 EGE08538.1 - 2.8 5.6 6.5 3.8 5.2 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Vfa1 PF08432.10 EGE08538.1 - 3.1 8.1 9.0 4.9 7.4 9.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPL5 PF18168.1 EGE08538.1 - 3.6 6.8 7.1 5.6 6.2 7.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF4820 PF16091.5 EGE08538.1 - 3.7 6.8 10.1 6.5 6.0 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 EGE08538.1 - 5.1 5.8 8.5 7.7 5.2 8.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Prefoldin_2 PF01920.20 EGE08539.1 - 2.6e-20 72.3 6.2 3.4e-20 72.0 6.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Cnn_1N PF07989.11 EGE08539.1 - 0.0047 17.0 1.2 0.0047 17.0 1.2 2.1 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 T6PP_N PF18572.1 EGE08539.1 - 0.0052 16.6 1.9 0.02 14.7 1.9 1.8 1 1 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Fib_alpha PF08702.10 EGE08539.1 - 0.016 15.4 5.8 0.23 11.7 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 EGE08539.1 - 0.019 14.6 3.7 0.72 9.4 0.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EGE08539.1 - 0.023 14.1 0.7 0.032 13.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EGE08539.1 - 0.027 14.9 1.7 0.027 14.9 1.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Val_tRNA-synt_C PF10458.9 EGE08539.1 - 0.039 14.2 0.4 0.039 14.2 0.4 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm DUF3450 PF11932.8 EGE08539.1 - 0.049 12.9 5.5 0.67 9.2 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EGE08539.1 - 0.06 13.2 2.8 2.7 7.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2681 PF10883.8 EGE08539.1 - 0.061 13.7 4.9 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Spc24 PF08286.11 EGE08539.1 - 0.07 13.4 3.9 1.3 9.3 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tektin PF03148.14 EGE08539.1 - 0.08 11.7 6.4 0.15 10.8 0.4 2.0 2 0 0 2 2 2 0 Tektin family FlxA PF14282.6 EGE08539.1 - 0.086 12.8 8.2 1.6 8.8 3.7 2.2 2 0 0 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 EGE08539.1 - 0.095 12.9 5.3 0.34 11.1 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CdvA PF18822.1 EGE08539.1 - 0.12 12.2 5.8 0.52 10.2 1.4 2.6 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF4618 PF15397.6 EGE08539.1 - 0.12 11.8 6.4 0.62 9.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 EGE08539.1 - 0.34 11.4 5.9 6 7.4 5.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region PspA_IM30 PF04012.12 EGE08539.1 - 0.35 10.4 8.9 2.4 7.7 2.6 2.1 2 0 0 2 2 2 0 PspA/IM30 family DUF4200 PF13863.6 EGE08539.1 - 0.5 10.8 7.7 4.1 7.8 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin PF02996.17 EGE08539.1 - 0.51 10.3 6.5 2.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 EGE08539.1 - 0.81 10.3 7.4 11 6.7 2.9 2.2 2 0 0 2 2 2 0 SlyX DUF1664 PF07889.12 EGE08539.1 - 1.1 9.4 7.3 0.38 10.8 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.21 EGE08539.1 - 1.5 9.0 6.4 0.74 10.0 2.4 2.1 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 EGE08539.1 - 3 7.7 8.1 5.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator THOC7 PF05615.13 EGE08539.1 - 3.2 8.1 11.3 7.8 6.8 1.0 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Swi5 PF07061.11 EGE08539.1 - 4.4 7.5 8.9 5.7 7.1 2.3 2.2 2 0 0 2 2 2 0 Swi5 YabA PF06156.13 EGE08539.1 - 5.3 7.7 8.8 5.4 7.7 1.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA CoA_transf_3 PF02515.17 EGE08540.1 - 0.89 8.6 3.1 1.3 8.0 3.1 1.3 1 0 0 1 1 1 0 CoA-transferase family III Tmp39 PF10271.9 EGE08540.1 - 1.5 7.8 2.7 1.9 7.4 2.7 1.2 1 0 0 1 1 1 0 Putative transmembrane protein Borrelia_P83 PF05262.11 EGE08540.1 - 2.5 6.5 24.7 3.2 6.2 24.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FliL PF03748.14 EGE08540.1 - 4.7 7.9 12.5 19 5.9 11.4 2.3 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL RR_TM4-6 PF06459.12 EGE08540.1 - 5.1 6.8 19.4 10 5.9 19.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atg14 PF10186.9 EGE08540.1 - 6.5 5.7 13.6 8.5 5.4 13.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Polysacc_deac_1 PF01522.21 EGE08541.1 - 3.8e-28 97.9 0.1 6.2e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase LysM PF01476.20 EGE08541.1 - 1e-08 35.1 0.1 3.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 LysM domain Glyco_hydro_57 PF03065.15 EGE08541.1 - 0.00062 19.1 0.0 0.00084 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 EVI2A PF05399.11 EGE08541.1 - 3.2 7.3 11.3 5.9 6.4 11.3 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Mito_carr PF00153.27 EGE08542.1 - 3.8e-53 177.4 1.7 7.4e-19 67.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein eRF1_1 PF03463.15 EGE08542.1 - 0.17 11.9 0.0 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 eRF1 domain 1 DUF508 PF04370.12 EGE08542.1 - 0.21 11.3 5.3 0.44 10.3 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) KorB_C PF06613.11 EGE08543.1 - 0.14 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain Mucin PF01456.17 EGE08545.1 - 0.34 10.9 20.8 0.54 10.2 20.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BDHCT_assoc PF16204.5 EGE08545.1 - 2.4 7.8 8.6 4.4 6.9 8.6 1.5 1 1 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein DUF4834 PF16118.5 EGE08546.1 - 0.0056 17.6 0.0 1.4 9.9 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4690 PF15756.5 EGE08546.1 - 0.0086 16.7 1.9 0.027 15.1 1.9 1.9 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Rcd1 PF04078.13 EGE08547.1 - 7.7e-126 418.7 3.5 9.4e-126 418.4 3.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Lin-8 PF03353.15 EGE08547.1 - 0.059 12.9 10.5 0.076 12.6 10.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 EGE08547.1 - 0.68 8.4 8.3 0.85 8.1 8.3 1.1 1 0 0 1 1 1 0 Macoilin family EPL1 PF10513.9 EGE08547.1 - 0.71 10.2 5.9 1.1 9.7 5.9 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.9 EGE08547.1 - 1.6 6.9 17.1 1.9 6.7 17.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.13 EGE08547.1 - 1.6 7.4 5.7 0.17 10.7 0.6 1.7 2 0 0 2 2 2 0 Otopetrin DUF4407 PF14362.6 EGE08547.1 - 2.3 7.5 6.6 3.7 6.8 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.10 EGE08547.1 - 2.7 6.6 30.1 3.4 6.2 30.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 EGE08547.1 - 4.2 7.3 25.2 5.5 6.9 25.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 EGE08548.1 - 5.2e-09 35.9 12.7 2.6e-08 33.6 10.9 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EGE08548.1 - 0.0038 16.8 6.5 0.0038 16.8 6.5 2.0 2 0 0 2 2 2 1 PHD-finger DUF2252 PF10009.9 EGE08548.1 - 2.1 7.3 12.4 3.6 6.6 11.9 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) C1_2 PF03107.16 EGE08548.1 - 4.3 7.7 9.0 0.49 10.8 2.0 2.7 3 0 0 3 3 3 0 C1 domain PAXIP1_C PF15364.6 EGE08552.1 - 0.0097 16.2 1.8 0.017 15.4 1.4 1.7 1 1 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein HMG_box PF00505.19 EGE08552.1 - 0.012 16.0 0.2 0.027 14.9 0.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box Sld5 PF05916.11 EGE08553.1 - 1.1e-12 48.4 0.1 2.5e-12 47.2 0.1 1.6 1 1 0 1 1 1 1 GINS complex protein INT_SG_DDX_CT_C PF15300.6 EGE08553.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sulfate_transp PF00916.20 EGE08555.1 - 8.3e-61 205.8 22.2 1.5e-60 205.0 22.2 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EGE08555.1 - 1.8e-14 53.5 0.0 3.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EGE08555.1 - 1.3e-11 44.1 0.1 2.5e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain PH_6 PF15406.6 EGE08556.1 - 3.1e-35 120.9 2.3 3.1e-35 120.9 2.3 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EGE08556.1 - 5.6e-10 39.7 0.0 1.8e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PH domain PNTB PF02233.16 EGE08557.1 - 4e-166 553.5 36.9 1.9e-161 538.1 27.4 2.9 3 0 0 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGE08557.1 - 2.2e-50 170.9 0.9 2.2e-50 170.9 0.9 2.9 3 1 1 4 4 4 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGE08557.1 - 1.3e-42 145.3 0.0 3.2e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGE08557.1 - 4.3e-30 104.0 3.0 4.3e-30 104.0 3.0 5.3 3 1 4 7 7 7 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGE08557.1 - 0.00071 19.0 1.1 1.2 8.4 0.1 3.4 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGE08557.1 - 0.031 13.5 1.1 0.048 12.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EGE08557.1 - 0.031 14.0 0.8 0.18 11.6 0.4 2.5 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 EGE08557.1 - 0.064 13.2 0.5 0.27 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GIDA PF01134.22 EGE08557.1 - 0.082 12.0 0.6 0.15 11.1 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EGE08557.1 - 5.8 7.2 8.3 0.57 10.5 1.3 3.2 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain bZIP_2 PF07716.15 EGE08558.1 - 1.2e-07 31.7 8.2 2.8e-07 30.5 8.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EGE08558.1 - 1.3e-07 31.6 7.7 2.5e-07 30.7 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Sugarporin_N PF11471.8 EGE08558.1 - 0.011 15.6 5.2 0.033 14.1 5.2 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension bZIP_Maf PF03131.17 EGE08558.1 - 0.012 16.1 6.4 0.034 14.6 6.4 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor ASD2 PF08687.11 EGE08558.1 - 0.016 14.8 0.8 0.028 14.0 0.8 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DUF4094 PF13334.6 EGE08558.1 - 0.13 12.7 0.7 0.28 11.6 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Asn_synthase PF00733.21 EGE08559.1 - 1.9e-14 54.1 1.5 5.8e-05 22.9 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EGE08559.1 - 1.4e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGE08559.1 - 0.0053 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 EGE08559.1 - 0.018 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 EGE08559.1 - 0.23 10.6 0.1 0.45 9.6 0.1 1.4 1 0 0 1 1 1 0 NAD synthase VPS9 PF02204.18 EGE08560.1 - 1.6e-30 105.4 0.1 2.8e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGE08560.1 - 1.1e-16 60.9 0.1 3.1e-16 59.4 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EGE08560.1 - 8.3e-09 35.0 0.2 2.2e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 CUE domain VIT1 PF01988.19 EGE08562.1 - 1.6e-60 204.6 2.7 1.9e-60 204.4 2.7 1.0 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.11 EGE08562.1 - 0.0013 18.7 0.7 0.0019 18.1 0.7 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF4202 PF13875.6 EGE08563.1 - 3e-77 258.7 3.0 3.5e-77 258.5 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Thr_synth_N PF14821.6 EGE08564.1 - 1.7e-27 95.4 0.0 6.2e-27 93.6 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EGE08564.1 - 3.7e-16 59.4 0.0 5.4e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HAD_2 PF13419.6 EGE08565.1 - 7.9e-07 29.3 0.0 2.9e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE08565.1 - 6.9e-06 26.5 0.0 9.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rox3 PF08633.10 EGE08566.1 - 1.3e-36 126.8 0.0 1.3e-36 126.8 0.0 2.1 2 1 1 3 3 3 1 Rox3 mediator complex subunit Hamartin PF04388.12 EGE08566.1 - 9.9 4.7 7.9 12 4.4 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein Fungal_trans PF04082.18 EGE08567.1 - 7.8e-12 44.8 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE08567.1 - 5.9e-08 32.7 13.0 1.1e-07 31.8 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GARP PF16731.5 EGE08567.1 - 0.061 13.0 0.8 0.12 12.1 0.8 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma SOG2 PF10428.9 EGE08567.1 - 0.084 12.1 9.3 0.18 11.0 9.3 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M14 PF00246.24 EGE08568.1 - 2.1e-82 277.2 0.1 4.9e-82 276.0 0.0 1.6 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGE08568.1 - 2.6e-11 43.7 0.1 5.6e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide AstE_AspA PF04952.14 EGE08568.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_S8 PF00082.22 EGE08571.1 - 4.2e-29 101.7 10.9 6.8e-29 101.1 10.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE08571.1 - 2.6e-14 53.6 0.0 4.7e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.22 EGE08572.1 - 2.5e-65 221.0 0.0 3.4e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.6 EGE08573.1 - 3.2e-109 364.9 1.1 4.7e-109 364.4 1.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) FA_hydroxylase PF04116.13 EGE08574.1 - 1.9e-19 70.3 15.9 1.1e-18 67.8 13.3 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily p450 PF00067.22 EGE08575.1 - 7e-39 133.8 0.0 9.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EGE08576.1 - 2.1e-15 56.5 0.7 3.2e-15 55.9 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE08576.1 - 7.1e-08 32.5 9.2 1.6e-07 31.4 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIP_1 PF08995.10 EGE08576.1 - 0.17 12.3 4.4 32 5.0 0.0 2.7 2 1 1 3 3 3 0 Necrosis inducing protein-1 IU_nuc_hydro PF01156.19 EGE08578.1 - 3.2e-58 197.7 0.1 4.3e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 EGE08578.1 - 0.001 18.9 0.2 0.042 13.7 0.0 2.5 2 0 0 2 2 2 1 Transketolase, C-terminal domain HLH PF00010.26 EGE08579.1 - 4.3e-14 52.2 0.7 1e-13 51.0 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GDH_N PF12466.8 EGE08579.1 - 0.028 14.6 0.3 0.11 12.8 0.3 2.0 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Spt20 PF12090.8 EGE08579.1 - 0.13 11.9 21.1 0.013 15.1 16.6 1.6 2 0 0 2 2 2 0 Spt20 family ALMT PF11744.8 EGE08579.1 - 2.5 6.8 4.1 4.4 6.0 4.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Glycos_transf_1 PF00534.20 EGE08581.1 - 4.6e-13 49.1 0.0 8.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGE08581.1 - 1.2e-07 32.3 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGE08581.1 - 0.071 13.5 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Amidase PF01425.21 EGE08582.1 - 3.3e-94 316.4 0.0 5.5e-94 315.7 0.0 1.3 1 1 0 1 1 1 1 Amidase Oxidored_q2 PF00420.24 EGE08583.1 - 0.049 13.2 0.0 0.092 12.4 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PTPS_related PF10131.9 EGE08584.1 - 0.11 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Mito_carr PF00153.27 EGE08585.1 - 1.5e-65 217.2 0.9 4.6e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 EGE08585.1 - 0.037 14.0 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Dna2 PF08696.11 EGE08586.1 - 1.5e-66 224.1 0.0 4.1e-66 222.7 0.0 1.8 2 0 0 2 2 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EGE08586.1 - 2.3e-53 180.8 0.0 4.4e-53 179.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGE08586.1 - 1.6e-33 116.6 0.1 2.3e-17 63.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EGE08586.1 - 3.1e-14 53.1 0.0 5.7e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGE08586.1 - 4e-11 43.4 0.1 9.5e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EGE08586.1 - 6.2e-09 36.2 0.0 8.9e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 EGE08586.1 - 1.4e-08 35.0 0.0 1.8e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EGE08586.1 - 6.7e-07 29.3 0.5 0.21 11.3 0.0 4.0 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EGE08586.1 - 8.6e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EGE08586.1 - 0.00066 19.3 0.8 0.0014 18.2 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EGE08586.1 - 0.0011 18.7 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EGE08586.1 - 0.0037 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Csa1 PF06023.12 EGE08586.1 - 0.0071 15.7 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 CRISPR-associated exonuclease Csa1 PIF1 PF05970.14 EGE08586.1 - 0.017 14.3 0.2 0.056 12.6 0.2 1.8 1 1 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 EGE08586.1 - 0.022 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGE08586.1 - 0.03 14.3 0.0 0.11 12.5 0.1 1.9 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 EGE08586.1 - 0.053 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain MobB PF03205.14 EGE08586.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 EGE08586.1 - 0.062 13.4 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EGE08586.1 - 0.062 13.7 0.1 0.22 11.9 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGE08586.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EGE08586.1 - 0.082 12.8 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 EGE08586.1 - 0.12 11.8 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.19 EGE08586.1 - 0.13 11.9 0.0 0.67 9.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGE08586.1 - 0.18 10.7 0.1 0.38 9.7 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1179 PF06678.11 EGE08586.1 - 8 6.5 7.8 7.3 6.6 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Ribonuc_P_40 PF08584.11 EGE08587.1 - 1.4e-73 247.7 0.0 2.1e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 EGE08588.1 - 1.1e-28 98.8 13.0 3.7e-07 30.7 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08588.1 - 2.1e-16 60.0 0.0 0.0053 17.0 0.0 5.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGE08588.1 - 5.1e-08 31.8 0.0 0.0014 17.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGE08588.1 - 0.00021 21.2 0.0 0.13 12.1 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGE08588.1 - 0.044 12.7 0.0 5.1 5.9 0.0 3.1 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 EGE08588.1 - 0.074 11.8 0.0 0.31 9.7 0.0 1.9 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 EGE08588.1 - 0.1 12.6 4.1 4.5 7.3 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EGE08588.1 - 0.22 10.1 0.2 9.2 4.8 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 VID27 PF08553.10 EGE08588.1 - 0.27 10.3 0.1 4.5 6.2 0.1 2.0 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Fungal_trans PF04082.18 EGE08589.1 - 1.6e-17 63.4 0.1 3.2e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE08589.1 - 8.4e-10 38.6 9.6 1.9e-09 37.5 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCCD1 PF15707.5 EGE08589.1 - 0.18 12.3 0.5 4.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 Ribosomal_L2_C PF03947.18 EGE08590.1 - 1.9e-48 163.8 2.5 1e-34 119.5 1.5 2.7 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGE08590.1 - 2.6e-24 85.0 0.6 9.4e-24 83.2 0.5 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EGE08591.1 - 9.1e-47 158.0 0.1 5.5e-45 152.2 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGE08591.1 - 2.6e-32 111.4 0.1 4.9e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.23 EGE08592.1 - 5.9e-16 59.0 0.1 1.7e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EGE08592.1 - 9.3e-06 26.1 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGE08592.1 - 0.15 11.9 2.7 0.4 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 EGE08593.1 - 2.1e-09 37.4 0.0 1.3e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EGE08593.1 - 0.00086 18.7 0.0 0.0016 17.7 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 EGE08593.1 - 0.097 12.3 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.8 EGE08595.1 - 2.3e-21 75.7 3.5 5.1e-21 74.6 3.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) LTXXQ PF07813.12 EGE08595.1 - 0.0014 19.3 0.3 0.0014 19.3 0.3 2.6 2 0 0 2 2 2 1 LTXXQ motif family protein SID-1_RNA_chan PF13965.6 EGE08595.1 - 0.02 13.4 1.4 0.034 12.6 1.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.10 EGE08595.1 - 8 6.5 9.4 12 5.9 6.9 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.25 EGE08596.1 - 1.4e-05 24.7 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EGE08596.1 - 4.6e-05 22.9 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE08596.1 - 0.00024 21.1 0.0 0.00024 21.1 0.0 2.8 2 1 1 3 3 2 1 Phosphotransferase enzyme family GARP PF16731.5 EGE08596.1 - 0.021 14.5 8.7 0.038 13.7 8.7 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Choline_kinase PF01633.20 EGE08596.1 - 0.033 13.8 0.2 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Alanine_zipper PF11839.8 EGE08596.1 - 0.043 14.2 15.3 0.092 13.1 15.3 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein GAS PF13851.6 EGE08596.1 - 0.51 9.7 14.6 0.96 8.8 14.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FemAB PF02388.16 EGE08596.1 - 0.54 9.1 3.7 0.86 8.4 3.7 1.2 1 0 0 1 1 1 0 FemAB family DUF2514 PF10721.9 EGE08596.1 - 1.7 8.7 17.1 16 5.5 13.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FAM176 PF14851.6 EGE08596.1 - 2.8 7.6 10.0 5 6.8 0.2 2.9 2 0 0 2 2 2 0 FAM176 family CPSF100_C PF13299.6 EGE08596.1 - 3 8.0 7.7 2.5 8.3 1.8 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal YtxH PF12732.7 EGE08596.1 - 4.3 7.9 6.8 16 6.1 3.9 2.6 2 0 0 2 2 2 0 YtxH-like protein DUF2203 PF09969.9 EGE08596.1 - 5.8 7.7 10.7 34 5.2 9.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Borrelia_P83 PF05262.11 EGE08596.1 - 8.2 4.8 14.5 14 4.0 14.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PIEZO PF15917.5 EGE08596.1 - 9.5 5.6 9.9 7.6 6.0 2.8 2.6 2 1 0 2 2 2 0 Piezo SIR2 PF02146.17 EGE08597.1 - 2.8e-59 200.0 0.0 4e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EGE08597.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EGE08597.1 - 0.0007 19.3 0.2 1.3 8.7 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_2 PF07719.17 EGE08598.1 - 1.1e-13 50.2 0.0 0.0001 22.1 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGE08598.1 - 6e-11 42.7 0.7 2.5e-05 24.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGE08598.1 - 1.2e-10 41.5 0.1 1.8e-06 28.1 0.0 3.7 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE08598.1 - 3.7e-10 39.2 0.0 1.4e-05 24.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE08598.1 - 4.4e-10 38.9 0.0 0.00031 20.4 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08598.1 - 5.2e-10 39.3 3.4 0.047 14.5 0.0 5.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08598.1 - 7.4e-07 29.7 0.0 2 9.1 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE08598.1 - 9.7e-06 25.6 1.2 1.3 9.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08598.1 - 7.4e-05 22.4 0.0 0.00078 19.1 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 EGE08598.1 - 0.00024 20.9 0.1 0.081 13.0 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGE08598.1 - 0.00025 20.8 0.2 4 7.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE08598.1 - 0.00058 20.0 0.0 0.62 10.3 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EGE08598.1 - 0.0024 17.3 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region TPR_15 PF13429.6 EGE08598.1 - 0.014 14.6 0.0 0.35 10.0 0.0 2.8 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGE08598.1 - 0.015 15.0 0.0 0.45 10.2 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 EGE08598.1 - 0.031 14.5 0.1 1.3 9.3 0.0 2.8 2 0 0 2 2 2 0 Tetratrico peptide repeat SHNi-TPR PF10516.9 EGE08598.1 - 0.033 13.6 0.3 5.6 6.5 0.1 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.6 EGE08598.1 - 0.045 14.1 0.0 1.2e+02 3.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE08598.1 - 0.083 13.6 2.8 0.6 10.9 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat RWD PF05773.22 EGE08599.1 - 2.7e-24 85.7 1.8 2.7e-24 85.7 1.8 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EGE08599.1 - 8.8e-05 22.9 15.8 0.00034 21.0 15.4 2.2 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1682 PF07946.14 EGE08599.1 - 0.00088 18.6 7.0 0.0012 18.1 7.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1485 PF07364.12 EGE08599.1 - 0.042 13.1 0.1 0.27 10.5 0.0 1.9 1 1 1 2 2 2 0 Metallopeptidase family M81 UQ_con PF00179.26 EGE08599.1 - 0.15 11.7 0.1 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme MPM1 PF17234.2 EGE08599.1 - 2.8 8.2 9.8 1.4 9.2 7.4 1.5 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Putative_PNPOx PF01243.20 EGE08600.1 - 3.5e-06 27.1 0.0 6.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GST_C PF00043.25 EGE08601.1 - 2.7e-16 59.6 0.1 5.9e-16 58.5 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE08601.1 - 8.9e-14 51.6 0.0 2.6e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE08601.1 - 2.4e-11 43.7 0.0 4.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGE08601.1 - 2e-10 40.9 0.0 3.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE08601.1 - 1.4e-08 34.8 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGE08601.1 - 4.7e-08 32.9 0.2 1.4e-07 31.4 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EGE08601.1 - 0.0067 17.0 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Complex1_LYR PF05347.15 EGE08602.1 - 7.9e-10 38.6 0.1 2.9e-09 36.8 0.1 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1154 PF06631.11 EGE08602.1 - 0.49 10.5 5.2 0.64 10.1 3.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) UQ_con PF00179.26 EGE08603.1 - 5.9e-18 64.9 0.0 6.4e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DCB PF16213.5 EGE08604.1 - 1.5e-43 148.5 4.1 1.5e-43 148.5 4.1 3.6 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGE08604.1 - 1.2e-39 135.7 5.2 1.2e-39 135.7 5.2 4.8 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EGE08604.1 - 6.6e-20 70.9 1.9 6.6e-20 70.9 1.9 2.6 3 0 0 3 3 3 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EGE08604.1 - 0.00022 21.0 0.6 0.059 13.2 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Gly_acyl_tr_N PF06021.11 EGE08604.1 - 0.0033 17.5 0.5 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase Antimicrobial19 PF08225.11 EGE08604.1 - 0.26 11.0 1.2 0.56 9.9 0.0 2.3 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Vps26 PF03643.15 EGE08605.1 - 1.2e-128 427.9 0.1 1.4e-128 427.7 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGE08605.1 - 0.00057 20.0 0.1 2.1 8.4 0.0 3.3 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Peptidase_C14 PF00656.22 EGE08608.1 - 9.3e-63 212.5 0.0 1.3e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain 2-oxoacid_dh PF00198.23 EGE08609.1 - 1e-66 224.7 0.4 1.5e-66 224.2 0.4 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGE08609.1 - 7.7e-14 51.7 0.0 2e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 EGE08609.1 - 2.1e-12 46.7 0.0 5.9e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme PI-PLC-X PF00388.19 EGE08610.1 - 7.5e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF1598 PF07643.11 EGE08611.1 - 0.079 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) Ribosomal_L10 PF00466.20 EGE08611.1 - 0.088 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L10 F-box PF00646.33 EGE08612.1 - 0.11 12.4 0.5 0.41 10.6 0.2 2.0 2 0 0 2 2 2 0 F-box domain Glycos_transf_3 PF00591.21 EGE08613.1 - 2.6e-55 187.8 0.0 2.7e-46 158.2 0.1 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGE08613.1 - 6e-06 26.0 1.2 8.3e-06 25.6 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 EGE08614.1 - 2.2e-17 62.4 7.0 2.9e-17 62.0 7.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EGE08614.1 - 0.00072 19.5 0.3 0.00076 19.5 0.3 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 EGE08614.1 - 0.0024 17.9 0.2 0.0026 17.8 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DUF2197 PF09963.9 EGE08614.1 - 0.0047 17.2 2.8 0.22 11.8 0.2 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zinc-ribbon_6 PF10005.9 EGE08614.1 - 0.0055 17.4 0.5 0.0073 17.0 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGE08614.1 - 0.012 15.6 0.3 0.017 15.1 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EGE08614.1 - 0.015 15.4 0.7 0.027 14.6 0.7 1.4 1 0 0 1 1 1 0 Zinc ribbon domain GFA PF04828.14 EGE08614.1 - 0.016 15.6 1.0 2.5 8.5 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF1451 PF07295.11 EGE08614.1 - 0.019 15.0 0.3 0.021 14.8 0.3 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 EGE08614.1 - 0.019 14.9 0.4 0.027 14.5 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 EGE08614.1 - 0.021 14.4 1.6 1.4 8.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2757 PF10955.8 EGE08614.1 - 0.037 14.3 0.6 0.046 14.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Zn_ribbon_SprT PF17283.2 EGE08614.1 - 0.063 13.2 2.7 0.11 12.5 2.7 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Zn_ribbon_recom PF13408.6 EGE08614.1 - 0.12 12.9 5.4 2.1 8.9 0.9 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain DUF951 PF06107.11 EGE08614.1 - 0.31 11.0 3.3 0.97 9.4 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TFIIS_C PF01096.18 EGE08614.1 - 0.91 9.4 4.9 7.5 6.5 0.7 2.5 1 1 0 2 2 2 0 Transcription factor S-II (TFIIS) fn3 PF00041.21 EGE08615.1 - 2.7e-11 43.7 5.4 2.3e-06 27.8 0.0 4.4 4 1 0 4 4 4 2 Fibronectin type III domain Lipase_GDSL_2 PF13472.6 EGE08615.1 - 4.5e-11 43.5 0.0 1.2e-08 35.5 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Fe_hyd_lg_C PF02906.14 EGE08617.1 - 1.7e-50 172.0 0.0 3.3e-50 171.0 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.9 EGE08618.1 - 3.5e-19 69.6 0.0 1.4e-18 67.6 0.0 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.24 EGE08619.1 - 3e-34 118.1 0.0 6.5e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EGE08619.1 - 8.8e-21 73.7 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EGE08619.1 - 0.0055 15.5 0.0 0.012 14.4 0.0 1.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Mitofilin PF09731.9 EGE08619.1 - 0.024 13.5 7.0 0.032 13.1 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pol_alpha_B_N PF08418.10 EGE08619.1 - 1.1 9.1 13.6 1.6 8.6 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.12 EGE08619.1 - 1.8 8.3 5.6 2.8 7.7 5.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cid2 PF09774.9 EGE08620.1 - 1.8e-56 191.0 0.1 2.1e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 EGE08621.1 - 1.1e-215 717.5 7.9 1.5e-214 713.7 3.6 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EGE08621.1 - 1.9e-23 81.1 12.3 0.0013 19.4 1.6 10.7 8 2 3 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08621.1 - 4.6e-21 73.2 35.1 9.8e-05 22.2 0.5 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGE08621.1 - 2.2e-19 69.7 23.6 6.3e-05 23.4 0.0 7.4 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08621.1 - 4.1e-17 62.5 12.1 0.0026 18.3 1.7 7.9 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGE08621.1 - 5.3e-13 48.2 33.6 1.5e-05 24.6 0.6 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGE08621.1 - 1.7e-12 47.4 12.7 0.057 13.7 0.3 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGE08621.1 - 1.1e-11 44.6 12.1 0.0017 18.5 0.0 7.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGE08621.1 - 2.1e-10 40.0 28.3 0.00032 20.7 0.3 8.6 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08621.1 - 6.2e-10 38.6 15.9 0.0004 20.0 1.4 6.6 7 0 0 7 7 7 2 TPR repeat ANAPC3 PF12895.7 EGE08621.1 - 1.9e-09 37.6 15.4 0.00025 21.2 3.4 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGE08621.1 - 1.2e-08 34.8 16.1 0.051 14.0 0.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_21 PF09976.9 EGE08621.1 - 1.5e-07 31.3 8.2 7.5e-05 22.5 0.1 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 EGE08621.1 - 3.2e-07 29.9 13.0 0.0035 16.6 1.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGE08621.1 - 1.4e-05 25.4 20.8 0.16 12.7 0.2 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE08621.1 - 3.6e-05 23.5 14.1 1 9.6 0.4 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE08621.1 - 0.0001 21.8 5.5 1.7 7.9 0.9 4.0 2 1 2 4 4 4 3 MalT-like TPR region BTAD PF03704.17 EGE08621.1 - 0.00036 21.0 2.4 0.0036 17.7 0.2 3.2 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_3 PF07720.12 EGE08621.1 - 0.0011 18.9 7.7 0.06 13.4 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGE08621.1 - 0.0087 16.6 8.0 3.9 8.4 2.1 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGE08621.1 - 0.013 15.5 13.6 13 6.0 0.1 6.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Rapsyn_N PF10579.9 EGE08621.1 - 0.023 14.8 0.1 0.11 12.6 0.1 2.2 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region ATP-synt_Eps PF04627.13 EGE08621.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.7 3 0 0 3 3 2 0 Mitochondrial ATP synthase epsilon chain TPR_20 PF14561.6 EGE08621.1 - 0.9 9.9 6.0 9.2 6.7 0.4 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat Tim54 PF11711.8 EGE08622.1 - 9.2e-140 465.7 0.0 1.1e-139 465.4 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 EGE08623.1 - 4.6e-56 190.1 0.0 7.8e-55 186.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08623.1 - 1.2e-24 87.0 0.3 5.3e-19 68.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE08623.1 - 4.3e-06 25.9 0.1 6.2e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGE08623.1 - 0.00027 20.9 0.2 0.039 13.9 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE08623.1 - 0.00072 19.0 0.2 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGE08623.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NFACT-C PF11923.8 EGE08623.1 - 0.032 14.1 0.4 0.067 13.1 0.4 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Pkinase_fungal PF17667.1 EGE08623.1 - 0.042 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EGE08623.1 - 0.049 12.7 0.0 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepX_N PF09168.10 EGE08623.1 - 0.063 13.7 0.7 0.14 12.6 0.7 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Pox_ser-thr_kin PF05445.11 EGE08623.1 - 0.076 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EGE08623.1 - 0.49 10.0 2.4 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 EGE08624.1 - 3.3e-37 126.8 0.0 4.8e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGE08624.1 - 1.2e-05 25.5 0.5 2.1e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EGE08624.1 - 0.05 13.2 1.5 0.11 12.0 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Methyltransf_11 PF08241.12 EGE08625.1 - 4.2e-12 46.5 0.0 1.1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08625.1 - 2.1e-09 38.0 0.0 5.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE08625.1 - 4e-07 30.7 0.0 7.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08625.1 - 0.0037 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08625.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGE08625.1 - 0.054 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ERG4_ERG24 PF01222.17 EGE08626.1 - 1.3e-137 459.1 21.1 1.5e-137 458.9 21.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MFS_1 PF07690.16 EGE08627.1 - 1.3e-40 139.4 34.8 2e-40 138.8 31.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08627.1 - 7.8e-12 44.8 11.5 7.8e-12 44.8 11.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGE08627.1 - 9.4e-05 21.4 0.6 0.01 14.7 0.6 3.0 1 1 0 1 1 1 1 MFS_1 like family CAP_GLY PF01302.25 EGE08628.1 - 1.3e-20 73.2 0.1 2.1e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EGE08628.1 - 1.7e-14 53.7 13.6 0.00096 19.5 0.0 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGE08628.1 - 7.5e-06 25.6 5.6 0.0066 16.0 0.4 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGE08628.1 - 5.4e-05 22.9 24.5 0.013 15.2 2.8 5.8 4 2 3 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 EGE08628.1 - 6.6e-05 22.6 5.7 2 8.6 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 EGE08628.1 - 0.018 15.5 10.7 39 5.4 0.0 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat zf-U1 PF06220.12 EGE08629.1 - 6.7e-08 32.2 0.5 1.1e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger Zn_clus PF00172.18 EGE08630.1 - 1.1e-08 35.0 10.4 1.9e-08 34.3 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 EGE08631.1 - 9.4e-57 191.2 0.0 1.3e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGE08631.1 - 1.2e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGE08631.1 - 0.00016 21.9 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CwfJ_C_1 PF04677.15 EGE08632.1 - 2.9e-29 101.4 0.0 6e-29 100.4 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGE08632.1 - 2e-18 67.1 0.0 4.7e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 EGE08632.1 - 0.37 11.3 6.6 1.3 9.5 0.1 3.2 4 0 0 4 4 4 0 Fumarase C C-terminus ATP_bind_1 PF03029.17 EGE08633.1 - 1.3e-70 237.9 0.0 1.9e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGE08633.1 - 0.00016 21.3 0.0 0.01 15.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EGE08633.1 - 0.00063 18.8 0.0 0.12 11.4 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EGE08633.1 - 0.00081 19.5 0.0 0.02 15.0 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGE08633.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EGE08633.1 - 0.0012 18.5 0.0 0.031 13.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PRK PF00485.18 EGE08633.1 - 0.0035 17.1 0.0 0.0096 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 EGE08633.1 - 0.0046 17.2 0.0 0.93 9.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGE08633.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 EGE08633.1 - 0.006 16.1 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 EGE08633.1 - 0.0094 15.6 0.0 1.6 8.3 0.0 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EGE08633.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 EGE08633.1 - 0.012 14.8 0.0 0.47 9.5 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 EGE08633.1 - 0.015 15.7 0.0 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EGE08633.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EGE08633.1 - 0.024 14.4 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 EGE08633.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGE08633.1 - 0.025 15.1 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGE08633.1 - 0.026 14.8 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGE08633.1 - 0.027 13.9 0.0 2.7 7.4 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGE08633.1 - 0.029 14.3 0.0 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 EGE08633.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GST_N_3 PF13417.6 EGE08634.1 - 7.5e-20 71.1 0.0 1.7e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGE08634.1 - 6.3e-16 58.4 0.0 1.9e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGE08634.1 - 1.7e-07 31.5 0.0 3.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE08634.1 - 1.7e-06 27.9 0.1 3.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2722 PF10846.8 EGE08634.1 - 2.2e-05 23.6 13.9 2.2e-05 23.6 13.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TERB2 PF15101.6 EGE08634.1 - 0.0029 17.7 6.7 0.0029 17.7 6.7 2.4 2 0 0 2 2 2 1 Telomere-associated protein TERB2 GST_C_5 PF16865.5 EGE08634.1 - 0.024 15.2 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGE08634.1 - 0.028 14.6 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF4770 PF15994.5 EGE08634.1 - 0.048 13.9 7.9 0.06 13.6 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Glutaredoxin PF00462.24 EGE08634.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF4471 PF14740.6 EGE08634.1 - 0.2 10.8 5.1 0.059 12.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Spt20 PF12090.8 EGE08634.1 - 0.48 10.0 33.2 0.017 14.7 25.8 2.2 2 0 0 2 2 2 0 Spt20 family DUF4175 PF13779.6 EGE08634.1 - 2 6.2 20.3 2.8 5.7 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GTA_holin_3TM PF11351.8 EGE08634.1 - 6.5 7.3 9.1 14 6.3 9.1 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Androgen_recep PF02166.16 EGE08634.1 - 7.5 5.3 28.2 13 4.5 28.2 1.3 1 0 0 1 1 1 0 Androgen receptor SUZ PF12752.7 EGE08635.1 - 1.1e-05 26.1 5.9 1.1e-05 26.1 5.9 4.0 3 2 0 3 3 3 1 SUZ domain GRP PF07172.11 EGE08635.1 - 8.1 7.2 12.8 4.1 8.2 9.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family Barttin PF15462.6 EGE08636.1 - 1.5 8.5 4.8 0.41 10.4 0.5 1.9 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Serglycin PF04360.12 EGE08637.1 - 0.084 12.8 0.6 0.21 11.5 0.6 1.6 1 0 0 1 1 1 0 Serglycin BCDHK_Adom3 PF10436.9 EGE08640.1 - 1.8e-72 242.4 0.0 2.6e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Creb_binding PF09030.10 EGE08642.1 - 0.074 13.8 0.6 0.1 13.3 0.6 1.2 1 0 0 1 1 1 0 Creb binding Ank_2 PF12796.7 EGE08643.1 - 2e-27 95.6 0.7 9.5e-11 42.1 0.1 4.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08643.1 - 1e-22 80.2 2.4 5.3e-10 39.6 0.2 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08643.1 - 1.8e-18 64.7 2.3 0.0042 17.5 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EGE08643.1 - 1.1e-17 63.6 3.8 0.003 17.9 0.1 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGE08643.1 - 1.5e-16 60.2 1.9 8.2e-06 26.0 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.12 EGE08643.1 - 7.6e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGE08643.1 - 1.5e-05 25.3 0.0 7.6e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Exo70 PF03081.15 EGE08644.1 - 1.2e-87 294.4 0.0 1.9e-87 293.8 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Laminin_II PF06009.12 EGE08644.1 - 0.37 10.8 2.2 3.6 7.6 0.3 2.7 2 0 0 2 2 2 0 Laminin Domain II Sec34 PF04136.15 EGE08644.1 - 0.41 10.5 2.3 4.6 7.1 0.0 3.5 3 2 1 4 4 4 0 Sec34-like family PLA2_B PF01735.18 EGE08645.1 - 7.6e-28 97.2 0.0 1.1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PPR_2 PF13041.6 EGE08646.1 - 1.2e-15 57.4 0.0 0.04 14.1 0.1 7.3 5 2 3 8 8 8 5 PPR repeat family PPR PF01535.20 EGE08646.1 - 7.4e-12 44.7 5.9 0.054 13.8 0.0 7.6 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 EGE08646.1 - 2.4e-11 43.5 0.3 0.32 11.1 0.0 6.7 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EGE08646.1 - 3.5e-10 39.6 0.0 0.0053 16.2 0.1 3.7 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP Dak1_2 PF13684.6 EGE08646.1 - 0.048 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Frtz PF11768.8 EGE08646.1 - 0.064 11.6 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_7 PF13176.6 EGE08646.1 - 0.066 13.3 0.1 91 3.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DSPc PF00782.20 EGE08647.1 - 4.7e-10 39.4 0.0 8.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGE08647.1 - 8.7e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AChE_tetra PF08674.10 EGE08647.1 - 0.014 15.0 0.5 0.046 13.4 0.5 1.9 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PTPlike_phytase PF14566.6 EGE08647.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGE08647.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EGE08647.1 - 0.083 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) LSM PF01423.22 EGE08648.1 - 5.5e-18 64.4 0.0 7.1e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGE08648.1 - 0.0047 17.1 0.0 0.0059 16.7 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain His_Phos_1 PF00300.22 EGE08649.1 - 8.1e-28 97.4 0.0 1.9e-27 96.2 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 EGE08651.1 - 1.1e-06 28.4 0.1 2.6e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGE08651.1 - 0.013 15.4 0.3 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 F-box F-box PF00646.33 EGE08651.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain UBM PF14377.6 EGE08651.1 - 0.15 11.6 0.3 0.38 10.3 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin binding region MFS_1 PF07690.16 EGE08652.1 - 6.4e-20 71.4 24.1 7.9e-20 71.1 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08652.1 - 2.4e-05 23.4 9.7 9e-05 21.5 9.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter HNH_2 PF13391.6 EGE08653.1 - 5.6e-13 48.8 0.0 2e-11 43.9 0.0 2.4 1 1 0 1 1 1 1 HNH endonuclease NDC10_II PF16787.5 EGE08655.1 - 0.015 14.4 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 USP7_C2 PF14533.6 EGE08655.1 - 0.077 12.7 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal HNH_2 PF13391.6 EGE08657.1 - 2.7e-08 33.8 0.0 6.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF3246 PF11596.8 EGE08657.1 - 0.19 11.2 2.7 0.31 10.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) V-SNARE_C PF12352.8 EGE08658.1 - 7.5e-16 58.2 1.0 7.5e-16 58.2 1.0 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGE08658.1 - 9.3e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.9 EGE08658.1 - 0.0042 16.3 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sigma70_r4 PF04545.16 EGE08658.1 - 0.022 14.3 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Pox_EPC_I2-L1 PF12575.8 EGE08658.1 - 0.022 15.0 0.1 0.81 10.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 E2F_TDP PF02319.20 EGE08658.1 - 0.084 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain MCU PF04678.13 EGE08658.1 - 0.14 12.3 0.1 19 5.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CoA_binding_3 PF13727.6 EGE08659.1 - 0.013 15.6 1.8 0.043 13.8 0.6 2.4 3 0 0 3 3 3 0 CoA-binding domain UPF0220 PF05255.11 EGE08659.1 - 0.16 11.5 2.4 0.21 11.1 1.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) Ldh_1_C PF02866.18 EGE08660.1 - 9.1e-48 162.3 0.0 2e-47 161.2 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGE08660.1 - 6.9e-44 149.4 0.0 1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EGE08660.1 - 7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EGE08660.1 - 0.061 12.9 0.1 0.73 9.4 0.2 2.2 1 1 0 2 2 2 0 Family 4 glycosyl hydrolase AAA PF00004.29 EGE08661.1 - 6.9e-17 62.1 0.1 5.3e-16 59.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGE08661.1 - 0.00026 21.0 0.0 0.0008 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE08661.1 - 0.0012 19.1 0.5 0.014 15.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EGE08661.1 - 0.0014 19.0 0.0 0.0086 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGE08661.1 - 0.0059 16.3 0.5 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGE08661.1 - 0.022 15.1 0.0 0.085 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE08661.1 - 0.085 13.0 0.1 0.085 13.0 0.1 2.7 3 1 0 3 3 3 0 AAA domain Myb_DNA-bind_3 PF12776.7 EGE08662.1 - 0.0005 21.0 0.3 0.75 10.8 0.0 2.3 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE08662.1 - 0.00065 19.9 0.3 0.53 10.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EGE08662.1 - 0.026 14.6 1.7 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGE08662.1 - 0.055 13.9 2.4 0.17 12.3 0.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Trypsin_2 PF13365.6 EGE08663.1 - 7.1e-05 23.7 0.0 0.00025 22.0 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGE08663.1 - 0.0001 21.0 0.4 0.00032 19.4 0.4 1.7 1 1 0 1 1 1 1 Peptidase family S64 Trypsin PF00089.26 EGE08663.1 - 0.028 14.2 0.0 0.065 13.0 0.0 1.6 1 1 0 1 1 1 0 Trypsin Peptidase_S32 PF05579.13 EGE08663.1 - 0.04 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.21 EGE08663.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease HbrB PF08539.11 EGE08666.1 - 4e-50 170.1 0.4 1.2e-49 168.5 0.0 2.1 2 0 0 2 2 2 1 HbrB-like UPF0239 PF06783.11 EGE08666.1 - 5.5 7.2 6.3 6.1 7.1 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) SUIM_assoc PF16619.5 EGE08666.1 - 8.4 6.5 11.0 3.8 7.6 3.8 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 EGE08667.1 - 4.3e-73 241.9 1.3 3.4e-17 62.8 0.4 6.4 3 3 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08667.1 - 8.9e-64 211.1 5.4 3.7e-12 46.5 0.0 9.2 7 2 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08667.1 - 8.7e-55 176.3 4.9 0.00078 19.7 0.0 13.6 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EGE08667.1 - 1.1e-48 162.6 5.4 1.5e-07 31.6 0.0 12.0 2 1 9 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 EGE08667.1 - 3.8e-48 159.9 11.2 0.00026 21.3 0.0 13.2 13 0 0 13 13 13 10 Ankyrin repeat HNH_2 PF13391.6 EGE08668.1 - 1.1e-14 54.3 0.0 2.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease Gon7 PF08738.10 EGE08669.1 - 4.9e-13 49.1 2.1 1.3e-12 47.8 2.1 1.6 1 1 0 1 1 1 1 Gon7 family Vps39_1 PF10366.9 EGE08670.1 - 3.5e-29 101.2 0.0 2.7e-28 98.4 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EGE08670.1 - 2.6e-28 98.6 0.2 1.4e-27 96.3 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGE08670.1 - 1.5e-15 57.6 0.0 4.4e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 CNH domain TPR_1 PF00515.28 EGE08670.1 - 0.0013 18.5 0.0 28 4.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Clathrin PF00637.20 EGE08670.1 - 0.017 15.0 0.7 0.16 11.8 0.2 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS 6PF2K PF01591.18 EGE08671.1 - 2e-81 272.5 0.0 2.9e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGE08671.1 - 5.1e-41 140.5 0.0 7.8e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGE08671.1 - 2.3e-06 27.8 0.0 4.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain APH PF01636.23 EGE08674.1 - 5.9e-17 62.4 0.0 1e-16 61.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGE08674.1 - 0.00026 20.7 0.0 0.00062 19.4 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase HNH_2 PF13391.6 EGE08674.1 - 0.0028 17.7 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Fructosamin_kin PF03881.14 EGE08674.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Pkinase PF00069.25 EGE08675.1 - 5.8e-22 78.3 0.0 8.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08675.1 - 4.9e-21 75.2 0.0 9.2e-21 74.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE08675.1 - 0.0069 16.3 0.3 1.8 8.4 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE08675.1 - 0.025 13.9 0.1 0.052 12.9 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGE08675.1 - 0.027 14.1 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGE08675.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF5353 PF17304.2 EGE08676.1 - 3.3e-35 119.6 2.1 5.1e-35 119.0 2.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Rotamase PF00639.21 EGE08676.1 - 0.00026 21.9 0.8 0.00037 21.4 0.8 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Ax_dynein_light PF10211.9 EGE08676.1 - 0.031 14.2 4.5 0.042 13.8 4.5 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain OmpH PF03938.14 EGE08676.1 - 0.088 13.1 7.2 0.12 12.7 7.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 EGE08676.1 - 0.16 12.6 4.0 0.29 11.8 4.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGE08676.1 - 0.52 10.9 6.5 1.3 9.6 6.5 1.7 1 0 0 1 1 1 0 YtxH-like protein DUF4337 PF14235.6 EGE08676.1 - 0.95 9.6 4.5 1.4 9.0 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_B PF00430.18 EGE08676.1 - 1.4 9.1 8.7 2.1 8.4 8.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3292 PF11696.8 EGE08676.1 - 3.9 5.7 6.5 4.5 5.5 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) 2-oxoacid_dh PF00198.23 EGE08677.1 - 6e-75 251.7 0.0 7.5e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGE08677.1 - 2.6e-17 62.4 0.4 2.6e-17 62.4 0.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EGE08677.1 - 1e-15 57.8 1.2 2.8e-15 56.3 0.4 2.2 2 0 0 2 2 2 1 e3 binding domain SopE_GEF PF07487.13 EGE08677.1 - 0.04 14.0 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 SopE GEF domain Biotin_lipoyl_2 PF13533.6 EGE08677.1 - 0.082 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like Sec7 PF01369.20 EGE08678.1 - 4.5e-69 231.8 0.2 1.3e-68 230.3 0.2 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGE08678.1 - 4.9e-43 146.8 5.3 4.9e-43 146.8 5.3 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGE08678.1 - 3.1e-34 116.7 10.1 1.9e-32 111.0 0.1 6.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGE08678.1 - 3.4e-10 39.9 1.3 1.1e-08 34.9 0.0 3.5 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 NAD_binding_7 PF13241.6 EGE08679.1 - 1.7e-31 108.7 0.2 2.8e-31 108.1 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EGE08679.1 - 4.6e-29 99.9 0.0 7.1e-29 99.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EGE08679.1 - 6.1e-15 54.4 0.1 1.2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 EGE08679.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 EGE08679.1 - 0.038 13.2 0.1 0.057 12.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EGE08679.1 - 0.17 11.2 1.9 0.29 10.5 0.3 1.9 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.6 EGE08680.1 - 4.2e-35 120.2 0.3 7.9e-26 90.3 0.0 3.4 3 0 0 3 3 3 3 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGE08680.1 - 1.3e-33 116.6 0.1 6.5e-29 101.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGE08680.1 - 8.5e-11 41.6 0.0 2.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain CbiJ PF02571.14 EGE08680.1 - 0.11 11.9 0.1 0.38 10.2 0.0 1.9 2 1 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK DUF4073 PF13285.6 EGE08681.1 - 0.028 14.0 0.4 0.045 13.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Isochorismatase PF00857.20 EGE08683.1 - 5.6e-21 75.5 0.0 6.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_10 PF05971.12 EGE08684.1 - 7e-71 239.0 0.0 9.4e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGE08684.1 - 1.2e-06 28.2 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGE08684.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGE08684.1 - 0.0029 17.6 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE08684.1 - 0.0061 17.2 0.0 0.031 14.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08684.1 - 0.007 17.1 0.0 0.028 15.1 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain UPF0020 PF01170.18 EGE08684.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EGE08684.1 - 0.026 14.3 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 EGE08684.1 - 0.045 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase AviRa PF11599.8 EGE08684.1 - 0.097 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 EGE08684.1 - 0.14 13.0 0.0 0.5 11.1 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 EGE08684.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Imm17 PF15562.6 EGE08684.1 - 1.3 8.9 2.9 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 17 Complex1_LYR PF05347.15 EGE08685.1 - 6.1e-05 23.0 1.1 0.00013 21.9 1.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGE08685.1 - 0.16 12.7 4.2 0.18 12.6 2.6 1.9 2 0 0 2 2 2 0 Complex1_LYR-like Ank_4 PF13637.6 EGE08686.1 - 3.5e-10 40.2 0.7 3.3e-08 33.9 0.2 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE08686.1 - 2.9e-06 27.8 0.1 0.013 16.0 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGE08686.1 - 6e-05 23.2 1.7 0.0032 17.7 0.3 3.4 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08686.1 - 0.0016 18.8 2.9 0.058 14.0 0.2 3.9 4 1 0 4 4 3 1 Ankyrin repeat KilA-N PF04383.13 EGE08686.1 - 0.0047 16.8 0.2 0.0047 16.8 0.2 2.7 2 1 0 2 2 2 1 KilA-N domain Sec8_exocyst PF04048.14 EGE08686.1 - 0.079 12.9 4.1 0.28 11.1 4.1 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Mtr2 PF10429.9 EGE08686.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 FapA PF03961.13 EGE08686.1 - 0.11 11.1 5.4 0.2 10.2 5.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EGE08686.1 - 0.15 12.1 1.1 0.98 9.5 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 EGE08686.1 - 4.2 7.2 6.9 59 3.5 4.4 2.9 2 0 0 2 2 2 0 Septum formation initiator Ank PF00023.30 EGE08686.1 - 4.8 7.8 8.0 5.5 7.6 0.4 3.8 4 0 0 4 4 4 0 Ankyrin repeat DUF4407 PF14362.6 EGE08686.1 - 6.8 5.9 14.4 6.9 5.9 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Rick_17kDa_Anti PF05433.15 EGE08687.1 - 0.0015 18.4 24.1 0.0057 16.5 24.3 2.0 1 1 0 1 1 1 1 Glycine zipper 2TM domain TraT PF05818.12 EGE08687.1 - 0.0047 16.6 2.4 0.011 15.4 2.4 1.6 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Gly-zipper_Omp PF13488.6 EGE08687.1 - 0.016 15.2 18.3 0.047 13.7 18.3 1.9 1 0 0 1 1 1 0 Glycine zipper DUF755 PF05501.11 EGE08687.1 - 0.25 11.6 15.8 0.51 10.6 15.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med19 PF10278.9 EGE08687.1 - 0.68 9.9 13.1 1.1 9.2 13.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AP3D1 PF06375.11 EGE08687.1 - 3 8.1 14.5 5.1 7.3 14.5 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TFIIF_alpha PF05793.12 EGE08687.1 - 4.4 5.8 14.5 5.9 5.4 14.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1275 PF06912.11 EGE08688.1 - 5.6e-43 147.1 12.6 8.1e-43 146.6 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) AzlC PF03591.14 EGE08688.1 - 4.1 7.8 9.8 0.48 10.9 3.0 2.6 1 1 1 2 2 2 0 AzlC protein Oxidored_q6 PF01058.22 EGE08689.1 - 5.4e-07 29.5 0.0 8.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TPR_1 PF00515.28 EGE08690.1 - 0.0015 18.3 7.5 0.018 14.9 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08690.1 - 0.0015 18.1 0.0 0.0058 16.3 0.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 EGE08690.1 - 0.003 17.5 3.8 0.34 11.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08690.1 - 0.024 14.7 0.0 0.024 14.7 0.0 4.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGE08690.1 - 0.032 14.7 7.8 11 6.6 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGE08690.1 - 0.056 13.8 0.1 3.7 8.1 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08690.1 - 0.16 12.6 0.0 0.16 12.6 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGE08690.1 - 1.5 9.0 11.5 2.9 8.1 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGE08691.1 - 1.1e-36 126.4 0.1 1.6e-20 74.0 0.0 2.9 2 1 0 2 2 2 2 ABC transporter 4HB PF17947.1 EGE08691.1 - 1.1e-29 102.3 0.8 2.3e-29 101.3 0.8 1.6 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EGE08691.1 - 4.9e-15 56.1 1.0 0.00092 19.1 0.1 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE08691.1 - 1e-11 44.7 0.1 8.6e-05 22.1 0.1 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGE08691.1 - 7.1e-11 43.0 0.2 7.6e-05 23.3 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGE08691.1 - 2.5e-09 36.7 0.1 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGE08691.1 - 1.1e-08 35.1 0.0 7.3e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EGE08691.1 - 2.9e-07 30.9 0.0 0.0077 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGE08691.1 - 4e-07 30.1 0.0 0.003 17.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE08691.1 - 5.3e-07 30.2 0.1 0.14 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 EGE08691.1 - 3.2e-06 27.7 0.6 0.069 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EGE08691.1 - 7e-06 26.4 0.0 0.055 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EGE08691.1 - 1.2e-05 25.0 0.0 0.031 14.0 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 EGE08691.1 - 1.7e-05 24.0 0.1 0.093 11.7 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 EGE08691.1 - 3.2e-05 24.3 0.0 0.093 13.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EGE08691.1 - 3.5e-05 24.0 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 EGE08691.1 - 3.6e-05 23.7 0.0 0.044 13.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 EGE08691.1 - 4.5e-05 23.6 0.1 0.0046 17.0 0.0 2.5 2 1 0 2 2 2 1 Dynamin family RNA_helicase PF00910.22 EGE08691.1 - 6.4e-05 23.3 0.0 0.39 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 EGE08691.1 - 7e-05 22.7 0.5 0.39 10.4 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EGE08691.1 - 9.5e-05 22.6 0.0 0.27 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EGE08691.1 - 0.00011 21.9 0.1 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EGE08691.1 - 0.00034 20.4 0.0 0.56 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGE08691.1 - 0.0005 19.3 0.1 0.046 12.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EGE08691.1 - 0.00059 19.9 0.0 1.6 8.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain G-alpha PF00503.20 EGE08691.1 - 0.00099 18.4 0.1 0.85 8.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 EGE08691.1 - 0.0011 18.7 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Roc PF08477.13 EGE08691.1 - 0.0016 18.6 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGE08691.1 - 0.0034 17.2 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MukB PF04310.12 EGE08691.1 - 0.0036 17.2 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 1 MukB N-terminal AAA_13 PF13166.6 EGE08691.1 - 0.0068 15.1 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGE08691.1 - 0.0071 16.3 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 EGE08691.1 - 0.0074 15.8 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 EGE08691.1 - 0.0081 15.8 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 EGE08691.1 - 0.0085 15.8 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase ATP-synt_ab PF00006.25 EGE08691.1 - 0.0096 15.6 0.0 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CLP1_P PF16575.5 EGE08691.1 - 0.0099 15.7 0.0 0.75 9.6 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 EGE08691.1 - 0.01 15.8 0.1 1.2 9.0 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Ploopntkinase3 PF18751.1 EGE08691.1 - 0.011 15.6 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 EGE08691.1 - 0.012 15.3 0.0 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EGE08691.1 - 0.021 14.8 0.0 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGE08691.1 - 0.026 13.9 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGE08691.1 - 0.028 13.6 0.0 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EGE08691.1 - 0.031 13.9 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EGE08691.1 - 0.04 13.2 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Septin T2SSE PF00437.20 EGE08691.1 - 0.042 12.9 0.1 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein TsaE PF02367.17 EGE08691.1 - 0.052 13.5 0.2 16 5.5 0.0 3.1 3 1 1 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EGE08691.1 - 0.053 13.4 0.1 9.3 6.1 0.1 2.8 3 0 0 3 3 2 0 NTPase dNK PF01712.19 EGE08691.1 - 0.054 13.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Arf PF00025.21 EGE08691.1 - 0.089 12.2 0.0 4.9 6.6 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 EGE08691.1 - 0.11 12.0 0.3 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Erf4 PF10256.9 EGE08692.1 - 5.3e-41 139.4 0.0 7.8e-41 138.8 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Ring_hydroxyl_A PF00848.19 EGE08692.1 - 0.11 12.5 0.4 0.24 11.3 0.4 1.5 1 0 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) Lipase_3 PF01764.25 EGE08693.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.12 EGE08693.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EGE08693.1 - 0.051 14.2 0.0 0.072 13.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EGE08693.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MBDa PF16564.5 EGE08693.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 p55-binding region of Methyl-CpG-binding domain proteins MBD DUF900 PF05990.12 EGE08693.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) zf-C2H2_4 PF13894.6 EGE08694.1 - 2.6e-09 37.1 7.1 0.042 14.7 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EGE08694.1 - 1e-07 32.0 7.8 0.081 13.4 0.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGE08694.1 - 8.6e-06 26.0 2.1 0.022 15.1 2.1 3.1 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGE08694.1 - 0.00014 22.1 6.1 0.0072 16.7 1.6 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EGE08694.1 - 0.0022 17.7 2.3 0.0022 17.7 2.3 3.0 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EGE08694.1 - 0.0073 16.7 7.5 0.13 12.8 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 EGE08694.1 - 0.015 15.6 5.4 0.065 13.5 0.2 3.0 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EGE08694.1 - 0.053 13.5 5.1 0.26 11.3 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1360 PF07098.11 EGE08694.1 - 0.12 12.3 0.7 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1360) zf-C2H2_jaz PF12171.8 EGE08694.1 - 0.34 11.2 3.3 29 5.1 0.6 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 EGE08694.1 - 0.45 10.4 2.3 4.4 7.2 0.1 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Cyto_heme_lyase PF01265.17 EGE08695.1 - 1.4e-124 415.4 0.9 1.6e-124 415.3 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Paramyxo_NS_C PF02725.14 EGE08695.1 - 0.13 12.4 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Non-structural protein C Fungal_trans_2 PF11951.8 EGE08696.1 - 6e-07 28.6 0.0 1.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain SR-25 PF10500.9 EGE08696.1 - 7.9 6.0 22.5 0.15 11.7 13.9 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 EGE08697.1 - 7.1e-19 67.8 0.1 1.1e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 EGE08698.1 - 1.3e-43 149.8 0.1 1.6e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 EGE08699.1 - 1.2e-06 28.3 13.8 0.00013 21.7 8.3 2.3 2 0 0 2 2 2 2 Yip1 domain TFIIA PF03153.13 EGE08700.1 - 8.2 6.3 20.8 9.9 6.0 20.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UFD1 PF03152.14 EGE08702.1 - 1.2e-28 99.7 0.0 1.3e-26 93.1 0.0 2.7 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EGE08702.1 - 1.4e-06 28.4 0.1 5.4e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PEX-1N PF09262.11 EGE08702.1 - 0.13 12.7 0.2 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal DPPIV_N PF00930.21 EGE08703.1 - 3.6e-111 371.4 6.6 6e-111 370.6 6.6 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGE08703.1 - 3.2e-39 134.6 2.8 5.7e-39 133.8 2.8 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGE08703.1 - 0.022 15.4 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.20 EGE08703.1 - 0.069 13.6 0.0 0.56 10.7 0.0 2.5 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Hydrolase_4 PF12146.8 EGE08703.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cas6_N PF17952.1 EGE08704.1 - 0.088 13.1 0.1 0.33 11.2 0.1 1.7 1 1 0 1 1 1 0 Cas6 N-terminal domain Peptidase_S8 PF00082.22 EGE08705.1 - 5.8e-24 84.9 14.7 1.1e-23 83.9 14.7 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE08705.1 - 3.7e-14 53.1 0.1 6.8e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 MAPEG PF01124.18 EGE08706.1 - 4.1e-11 42.9 2.2 5e-11 42.6 2.2 1.2 1 0 0 1 1 1 1 MAPEG family MARVEL PF01284.23 EGE08707.1 - 4e-06 26.9 11.8 7.3e-06 26.1 11.9 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF1129 PF06570.11 EGE08707.1 - 1.6 8.2 4.4 3 7.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) ABC2_membrane_5 PF13346.6 EGE08707.1 - 2.2 7.8 14.3 0.18 11.3 7.9 2.1 1 1 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.6 EGE08707.1 - 2.9 7.5 6.1 5.5 6.6 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RNB PF00773.19 EGE08708.1 - 2.5e-53 181.5 0.0 2.6e-51 174.9 0.0 2.2 1 1 0 1 1 1 1 RNB domain Tom6 PF17112.5 EGE08709.1 - 0.00082 18.8 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal CTNNBL PF08216.11 EGE08710.1 - 8.9e-39 131.9 0.4 4.4e-38 129.6 0.2 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear PHTB1_C PF14728.6 EGE08710.1 - 0.013 14.6 0.3 0.024 13.7 0.3 1.3 1 0 0 1 1 1 0 PTHB1 C-terminus Mo25 PF08569.11 EGE08710.1 - 0.028 13.8 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Mo25-like HEAT_2 PF13646.6 EGE08710.1 - 0.034 14.5 0.3 0.37 11.2 0.0 2.8 2 1 1 3 3 3 0 HEAT repeats RNA_pol_Rpb2_6 PF00562.28 EGE08711.1 - 1.9e-123 412.4 0.7 2.5e-123 412.0 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGE08711.1 - 9.5e-60 201.6 0.0 2.6e-59 200.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGE08711.1 - 3e-47 160.7 0.0 5.3e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGE08711.1 - 2.5e-33 114.3 0.0 5.3e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGE08711.1 - 1.2e-25 89.4 0.1 3.2e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGE08711.1 - 1.3e-24 86.2 0.4 3.7e-24 84.8 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGE08711.1 - 7.1e-23 80.9 2.0 1.2e-22 80.2 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EGE08711.1 - 2 9.2 4.4 0.37 11.5 0.1 2.0 2 0 0 2 2 2 0 MRN-interacting protein AMPK1_CBM PF16561.5 EGE08713.1 - 3.4e-05 24.0 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF951 PF06107.11 EGE08713.1 - 0.11 12.4 0.7 0.2 11.6 0.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Nucleopor_Nup85 PF07575.13 EGE08715.1 - 8.5e-21 74.1 1.1 8.7e-17 60.9 0.0 2.8 3 0 0 3 3 3 2 Nup85 Nucleoporin ADH_zinc_N PF00107.26 EGE08717.1 - 1.3e-14 54.3 0.0 2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE08717.1 - 5.3e-08 34.0 0.0 8.3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE08717.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EGE08717.1 - 0.0031 16.9 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EGE08717.1 - 0.055 12.8 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 EGE08717.1 - 0.092 13.6 0.0 0.23 12.3 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Mito_fiss_Elm1 PF06258.11 EGE08717.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 TPR_19 PF14559.6 EGE08718.1 - 1.1e-15 57.9 17.2 0.00089 19.7 0.1 7.5 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08718.1 - 1.4e-13 50.3 6.7 0.00048 19.7 0.1 6.1 5 1 1 6 6 6 3 TPR repeat TPR_17 PF13431.6 EGE08718.1 - 8.7e-11 41.4 13.9 0.0018 18.5 0.1 7.0 9 0 0 9 9 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08718.1 - 3.1e-10 39.4 25.5 0.013 15.5 0.5 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08718.1 - 3.9e-10 39.7 13.3 0.47 11.4 0.0 8.9 7 2 3 10 10 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE08718.1 - 1.1e-08 35.6 7.1 0.00062 20.4 0.4 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE08718.1 - 2.2e-07 30.4 26.6 0.12 12.2 0.6 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE08718.1 - 2.5e-06 27.7 22.4 0.13 12.6 0.3 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGE08718.1 - 2.3e-05 24.3 24.4 0.29 11.5 0.4 8.3 10 0 0 10 10 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE08718.1 - 5.2e-05 23.4 12.4 0.021 15.1 0.1 5.8 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGE08718.1 - 0.00026 21.1 7.3 0.011 15.8 0.0 4.8 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGE08718.1 - 0.00026 20.8 11.7 7.3 6.9 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGE08718.1 - 0.0072 15.6 1.2 20 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EGE08718.1 - 0.0087 16.5 1.4 0.083 13.3 0.2 2.6 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EGE08718.1 - 0.028 13.8 2.8 1.6 8.0 0.2 3.9 3 1 1 4 4 4 0 MalT-like TPR region TPR_20 PF14561.6 EGE08718.1 - 0.029 14.7 3.1 2.6 8.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGE08718.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.9 EGE08718.1 - 0.13 11.9 1.3 16 5.1 0.4 3.5 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF2989 PF11207.8 EGE08718.1 - 0.25 11.1 2.6 12 5.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2989) TPR_10 PF13374.6 EGE08718.1 - 1.6 8.7 14.3 0.24 11.3 0.5 5.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE08718.1 - 5.5 7.9 13.3 0.65 10.8 0.2 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE08718.1 - 8.8 7.2 15.1 11 6.9 0.2 6.1 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF3336 PF11815.8 EGE08719.1 - 1.4e-47 160.9 1.5 2.3e-47 160.2 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGE08719.1 - 1.4e-18 67.8 0.5 6.2e-18 65.7 0.1 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase FA_desaturase PF00487.24 EGE08719.1 - 0.013 15.4 0.2 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Fatty acid desaturase LRR_8 PF13855.6 EGE08723.1 - 1.6e-12 47.0 20.4 1.9e-07 30.8 3.6 4.4 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EGE08723.1 - 2.8e-12 46.6 5.7 0.00027 21.2 0.1 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGE08723.1 - 1.9e-07 30.7 7.4 2.2 9.1 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EGE08723.1 - 3e-07 29.9 11.3 0.98 9.6 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich repeat Zip PF02535.22 EGE08723.1 - 0.0025 17.1 1.2 0.0025 17.1 1.2 3.0 2 1 0 2 2 2 1 ZIP Zinc transporter SART-1 PF03343.13 EGE08723.1 - 0.016 13.8 2.9 0.065 11.8 1.5 2.0 2 0 0 2 2 2 0 SART-1 family LRR_9 PF14580.6 EGE08723.1 - 0.046 13.2 0.3 0.54 9.7 0.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeat CHDCT2 PF08074.11 EGE08723.1 - 1.3 9.2 3.8 3.2 7.9 3.8 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Metallophos PF00149.28 EGE08725.1 - 2.4e-40 139.2 0.1 3.1e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGE08725.1 - 1.2e-22 80.1 2.6 1.5e-22 79.8 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 EGE08726.1 - 6.5e-64 214.6 0.0 7.3e-64 214.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGE08726.1 - 2.6e-09 36.7 0.0 1.1e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGE08726.1 - 2.5e-08 33.6 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGE08726.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGE08726.1 - 6.3e-06 26.4 0.0 1.4e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGE08726.1 - 0.00022 20.8 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGE08726.1 - 0.0025 17.2 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region mRNA_decap_C PF16741.5 EGE08726.1 - 0.094 12.0 0.2 0.65 9.3 0.1 2.1 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus DUF3435 PF11917.8 EGE08727.1 - 2.1e-59 201.5 0.2 1.5e-31 109.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2 PF00096.26 EGE08727.1 - 1.5 9.4 6.7 0.32 11.5 1.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE08727.1 - 3.5 8.7 8.8 0.32 11.9 0.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4764 PF15961.5 EGE08727.1 - 5.9 5.4 6.6 0.33 9.6 1.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4764) RRN3 PF05327.11 EGE08730.1 - 0.27 9.7 5.0 0.45 9.0 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PPP4R2 PF09184.11 EGE08730.1 - 7.8 6.0 19.9 0.11 12.1 3.7 2.7 3 0 0 3 3 3 0 PPP4R2 DUF3606 PF12244.8 EGE08733.1 - 0.096 12.6 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Myc-LZ PF02344.15 EGE08733.1 - 2.8 8.1 8.6 0.9 9.7 1.8 2.9 2 0 0 2 2 2 0 Myc leucine zipper domain Dabb PF07876.12 EGE08735.1 - 2e-23 82.8 0.1 2.3e-23 82.6 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ECD PF18432.1 EGE08735.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.5 1 1 1 2 2 2 0 Extracellular Cadherin domain NB-ARC PF00931.22 EGE08736.1 - 2.6e-19 69.4 0.0 5e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 EGE08736.1 - 3.6e-18 65.6 6.2 8.5e-08 32.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGE08736.1 - 4.8e-08 32.6 3.9 0.024 14.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08736.1 - 2.4e-07 30.3 5.0 0.034 14.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE08736.1 - 8.8e-06 25.3 7.2 1.7e-05 24.4 4.0 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 EGE08736.1 - 2.1e-05 24.3 5.1 1.2 9.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 EGE08736.1 - 4.3e-05 24.0 0.7 0.003 18.0 0.7 2.6 1 1 0 1 1 1 1 AAA ATPase domain TPR_1 PF00515.28 EGE08736.1 - 5.5e-05 22.8 0.8 0.038 13.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 EGE08736.1 - 0.00064 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain SNAP PF14938.6 EGE08736.1 - 0.0007 19.1 0.4 0.0033 16.9 0.1 2.0 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.6 EGE08736.1 - 0.0014 19.1 2.7 6.1 7.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE08736.1 - 0.0043 17.6 2.7 2.3 9.0 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat ATPase_2 PF01637.18 EGE08736.1 - 0.034 14.1 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_9 PF13371.6 EGE08736.1 - 0.35 11.1 1.5 0.76 10.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08736.1 - 0.38 10.5 2.9 0.92 9.2 0.0 3.0 4 0 0 4 4 3 0 TPR repeat TPR_16 PF13432.6 EGE08736.1 - 1.6 9.4 8.4 14 6.4 0.8 4.6 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08736.1 - 7.3 7.7 11.3 54 5.0 0.0 5.8 6 1 1 7 7 6 0 Tetratricopeptide repeat DEAD PF00270.29 EGE08737.1 - 1.1e-40 139.3 1.2 2.2e-40 138.3 1.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE08737.1 - 3.5e-31 107.8 0.1 4.5e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE08737.1 - 1.2e-07 31.9 0.0 3.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RIG-I_C PF18119.1 EGE08737.1 - 0.053 13.5 1.2 0.95 9.5 0.5 2.4 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Acyltransferase PF01553.21 EGE08739.1 - 4.1e-15 55.6 0.0 8.4e-15 54.6 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 EGE08740.1 - 3.7e-35 120.4 0.3 4.4e-35 120.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Pkinase PF00069.25 EGE08742.1 - 2.9e-13 49.8 0.0 6.6e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08742.1 - 0.00012 21.5 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DAG_kinase_N PF14513.6 EGE08743.1 - 0.11 12.7 2.2 0.21 11.8 2.2 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus bZIP_C PF12498.8 EGE08743.1 - 2.1 9.4 9.0 0.77 10.8 1.4 2.1 1 1 0 2 2 2 0 Basic leucine-zipper C terminal Annexin PF00191.20 EGE08744.1 - 3.3e-61 203.3 0.1 1.9e-17 63.1 0.0 4.1 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 EGE08744.1 - 0.00021 21.4 3.0 0.11 12.6 0.8 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF5617) EBP PF05241.12 EGE08745.1 - 1e-62 210.8 3.7 1.2e-62 210.5 3.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein HNH_2 PF13391.6 EGE08746.1 - 2.6e-16 59.5 0.1 5.9e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease DUF4320 PF14208.6 EGE08747.1 - 0.11 12.5 0.4 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) zf-RING_UBOX PF13445.6 EGE08748.1 - 4.2e-08 33.1 5.8 4.2e-08 33.1 5.8 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGE08748.1 - 6.1e-08 32.4 5.3 6.1e-08 32.4 5.3 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGE08748.1 - 3.2e-07 30.1 2.5 3.2e-07 30.1 2.5 4.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE08748.1 - 7.8e-06 26.1 6.9 7.8e-06 26.1 6.9 4.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_6 PF14835.6 EGE08748.1 - 1.6e-05 24.7 0.7 1.6e-05 24.7 0.7 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGE08748.1 - 0.00023 21.2 7.0 0.00023 21.2 7.0 3.8 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING SH3_9 PF14604.6 EGE08748.1 - 0.0014 18.4 0.1 0.0014 18.4 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EGE08748.1 - 0.17 11.5 0.2 0.36 10.5 0.2 1.5 1 0 0 1 1 1 0 SH3 domain Spt20 PF12090.8 EGE08748.1 - 0.23 11.0 10.3 0.5 9.9 10.3 1.5 1 0 0 1 1 1 0 Spt20 family Hydin_ADK PF17213.3 EGE08748.1 - 6.7 6.9 7.7 26 5.0 7.7 2.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CBM_21 PF03370.13 EGE08750.1 - 5.5e-13 49.1 0.0 1.7e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EGE08750.1 - 0.00073 20.1 0.2 0.0027 18.2 0.1 2.1 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) CENP-T_C PF15511.6 EGE08751.1 - 6.1e-09 36.0 0.1 7.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGE08751.1 - 1.9e-05 25.0 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGE08751.1 - 7e-05 22.9 0.1 0.0001 22.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGE08751.1 - 0.00017 21.8 0.1 0.00036 20.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGE08751.1 - 0.00021 21.6 0.1 0.00028 21.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGE08751.1 - 0.0038 17.3 0.0 0.0045 17.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGE08751.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 EGE08751.1 - 0.052 14.0 0.1 0.098 13.2 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 EGE08751.1 - 0.1 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Peptidase_M28 PF04389.17 EGE08752.1 - 2.7e-34 118.6 0.3 3.9e-34 118.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGE08752.1 - 0.00096 18.9 1.3 0.012 15.3 1.3 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Mito_carr PF00153.27 EGE08753.1 - 8.7e-07 28.8 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF2207 PF09972.9 EGE08755.1 - 0.048 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CRIM PF16978.5 EGE08756.1 - 1e-42 145.6 0.0 1.8e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EGE08756.1 - 1.2e-26 93.1 0.6 2.4e-26 92.2 0.6 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EGE08756.1 - 0.0094 16.2 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain Pkinase PF00069.25 EGE08757.1 - 1e-72 244.7 0.0 1.7e-72 243.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08757.1 - 4.9e-37 127.6 0.0 7.4e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE08757.1 - 1.4e-07 31.2 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF2252 PF10009.9 EGE08757.1 - 0.0029 16.7 0.1 0.004 16.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Haspin_kinase PF12330.8 EGE08757.1 - 0.021 13.8 1.0 0.034 13.1 1.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EGE08757.1 - 0.025 14.1 0.6 0.81 9.2 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EGE08757.1 - 0.039 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EGE08757.1 - 0.061 13.2 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-Tim10_DDP PF02953.15 EGE08758.1 - 3.5e-22 77.8 3.7 5.1e-22 77.3 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3475 PF11961.8 EGE08758.1 - 0.026 14.6 0.3 0.21 11.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3475) Lectin_leg-like PF03388.13 EGE08759.1 - 3.4e-61 206.5 0.0 4.8e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EGE08759.1 - 6.1e-07 29.7 0.0 9.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EGE08759.1 - 0.00021 20.9 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain BRF1 PF07741.13 EGE08760.1 - 0.016 15.6 17.4 0.032 14.6 9.3 2.8 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PRCC PF10253.9 EGE08761.1 - 7.4e-37 128.2 5.1 7.4e-37 128.2 5.1 3.7 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting HNH_2 PF13391.6 EGE08762.1 - 4.5e-15 55.5 0.1 8.7e-15 54.6 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease ATP-grasp_3 PF02655.14 EGE08763.1 - 7.2e-09 35.9 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EGE08763.1 - 7.8e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGE08763.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AAA_5 PF07728.14 EGE08764.1 - 6.6e-133 437.6 0.0 7.5e-24 84.3 0.0 10.1 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGE08764.1 - 6.9e-52 174.1 5.2 1e-20 73.9 0.0 5.9 5 0 0 5 5 5 4 Midasin AAA lid domain AAA PF00004.29 EGE08764.1 - 1.2e-30 106.6 0.0 0.00018 22.0 0.0 6.9 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EGE08764.1 - 3.3e-30 104.3 0.2 2e-29 101.8 0.0 2.6 3 0 0 3 3 1 1 Midasin AAA lid domain AAA_7 PF12775.7 EGE08764.1 - 4.8e-30 104.4 0.6 4.6e-05 23.0 0.0 6.9 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_3 PF07726.11 EGE08764.1 - 2.6e-29 101.7 0.0 5.8e-10 39.1 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGE08764.1 - 5.7e-27 95.2 12.0 9.8e-05 22.8 0.1 8.6 7 1 0 7 7 6 6 AAA ATPase domain Dynein_heavy PF03028.15 EGE08764.1 - 3e-20 72.5 0.4 1.9e-05 24.7 0.0 8.0 8 1 0 8 8 6 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 EGE08764.1 - 3e-19 69.3 0.0 0.02 14.6 0.0 6.5 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_6 PF12774.7 EGE08764.1 - 7.8e-19 67.8 0.0 0.0039 16.2 0.0 8.2 8 1 0 8 8 7 3 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EGE08764.1 - 1.5e-18 67.4 0.8 0.077 13.3 0.0 8.4 7 0 0 7 7 7 4 AAA domain TsaE PF02367.17 EGE08764.1 - 7.1e-17 61.6 0.9 0.08 12.9 0.0 6.8 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EGE08764.1 - 6e-15 55.9 0.2 0.63 10.6 0.0 7.1 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 EGE08764.1 - 2.3e-14 53.8 0.2 0.4 10.8 0.0 6.8 6 0 0 6 6 6 3 AAA domain AAA_30 PF13604.6 EGE08764.1 - 2.9e-14 53.2 0.1 0.051 13.3 0.0 7.6 7 1 0 7 7 6 1 AAA domain Mg_chelatase PF01078.21 EGE08764.1 - 7.6e-14 51.6 5.7 0.83 9.0 0.0 9.0 8 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGE08764.1 - 2.2e-13 50.4 0.0 0.0015 18.6 0.0 7.6 8 0 0 8 8 6 2 AAA domain ABC_tran PF00005.27 EGE08764.1 - 4.7e-13 49.8 6.6 0.039 14.4 0.0 7.4 7 0 0 7 7 6 3 ABC transporter RuvB_N PF05496.12 EGE08764.1 - 1.4e-12 47.7 2.3 0.18 11.5 0.0 6.7 7 0 0 7 7 6 4 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EGE08764.1 - 1.3e-11 44.7 5.5 0.15 12.0 0.1 7.0 6 0 0 6 6 6 2 NACHT domain RNA_helicase PF00910.22 EGE08764.1 - 4.9e-11 43.0 0.2 1.4 9.3 0.0 6.7 6 0 0 6 6 6 1 RNA helicase Sigma54_activ_2 PF14532.6 EGE08764.1 - 1.2e-10 41.7 1.5 0.045 13.9 0.0 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_19 PF13245.6 EGE08764.1 - 1.3e-10 41.7 2.0 4 7.8 0.1 6.8 6 0 0 6 6 6 0 AAA domain Rad17 PF03215.15 EGE08764.1 - 1.2e-09 38.4 1.0 0.059 13.3 0.0 6.2 6 0 0 6 6 6 1 Rad17 P-loop domain Zeta_toxin PF06414.12 EGE08764.1 - 2.1e-09 36.9 3.7 0.027 13.7 0.0 6.9 7 0 0 7 7 7 1 Zeta toxin IstB_IS21 PF01695.17 EGE08764.1 - 7.3e-09 35.6 0.0 2.4 7.9 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein SRP54 PF00448.22 EGE08764.1 - 1.1e-08 35.0 2.9 1.2 8.7 0.1 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGE08764.1 - 1.9e-08 33.9 0.3 2.3 8.0 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGE08764.1 - 4.2e-08 33.6 4.2 0.46 10.7 0.0 6.2 6 0 0 6 6 6 2 AAA domain PduV-EutP PF10662.9 EGE08764.1 - 5.3e-08 32.7 1.2 0.32 10.7 0.0 6.1 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EGE08764.1 - 7.4e-08 31.9 9.0 1.1 8.4 0.2 6.4 7 0 0 7 7 6 2 Protein of unknown function (DUF815) T2SSE PF00437.20 EGE08764.1 - 1e-07 31.3 0.3 0.11 11.5 0.0 4.9 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_24 PF13479.6 EGE08764.1 - 3.8e-07 30.0 0.0 5.3 6.7 0.0 6.3 6 0 0 6 6 6 0 AAA domain RsgA_GTPase PF03193.16 EGE08764.1 - 1.1e-06 28.7 7.8 1.2 9.0 0.5 6.0 6 0 0 6 6 6 1 RsgA GTPase Roc PF08477.13 EGE08764.1 - 1.1e-06 28.9 2.8 11 6.2 0.0 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EGE08764.1 - 1.4e-06 28.4 0.0 18 5.1 0.0 6.0 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGE08764.1 - 1.6e-06 27.9 7.1 2.8 7.5 0.0 6.3 7 0 0 7 7 5 1 AAA domain TIP49 PF06068.13 EGE08764.1 - 1.8e-06 27.4 1.9 1.1 8.4 0.0 5.1 5 0 0 5 5 5 1 TIP49 P-loop domain TniB PF05621.11 EGE08764.1 - 2.2e-06 27.2 0.1 7.8 5.9 0.0 5.6 6 0 0 6 6 5 0 Bacterial TniB protein MCM PF00493.23 EGE08764.1 - 1.1e-05 24.7 0.0 2.9 6.9 0.0 4.8 5 0 0 5 5 5 1 MCM P-loop domain ResIII PF04851.15 EGE08764.1 - 1.4e-05 25.2 0.1 2.3 8.2 0.0 5.4 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 EGE08764.1 - 5.6e-05 23.1 0.0 5.8 6.7 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein DnaB_C PF03796.15 EGE08764.1 - 0.00047 19.6 1.1 1.1 8.5 0.0 4.2 4 0 0 4 4 4 1 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 EGE08764.1 - 0.00074 19.5 6.2 1.4 8.8 0.0 5.3 6 0 0 6 6 4 1 NTPase AAA_17 PF13207.6 EGE08764.1 - 0.00095 19.6 1.5 13 6.2 0.0 4.7 4 0 0 4 4 4 0 AAA domain CPT PF07931.12 EGE08764.1 - 0.0015 18.4 1.9 1.5 8.6 0.0 5.2 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 EGE08764.1 - 0.002 17.5 0.1 14 4.9 0.0 4.6 4 0 0 4 4 4 0 KaiC Viral_helicase1 PF01443.18 EGE08764.1 - 0.005 16.6 0.1 14 5.3 0.0 5.0 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase GAF_2 PF13185.6 EGE08764.1 - 0.012 15.9 0.0 0.043 14.1 0.0 2.0 1 0 0 1 1 1 0 GAF domain MMR_HSR1 PF01926.23 EGE08764.1 - 0.015 15.4 3.1 55 3.9 0.0 6.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase PhoH PF02562.16 EGE08764.1 - 0.041 13.3 0.8 22 4.4 0.0 4.3 5 0 0 5 5 5 0 PhoH-like protein CbiA PF01656.23 EGE08764.1 - 0.073 13.1 0.8 13 5.9 0.1 4.0 5 0 0 5 5 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ploopntkinase3 PF18751.1 EGE08764.1 - 0.13 12.2 0.1 57 3.6 0.0 3.6 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 dNK PF01712.19 EGE08764.1 - 0.14 12.0 2.3 6.4 6.6 0.0 3.7 4 0 0 4 4 3 0 Deoxynucleoside kinase AAA_8 PF12780.7 EGE08764.1 - 0.38 10.0 9.4 31 3.8 0.0 6.3 8 0 0 8 8 7 0 P-loop containing dynein motor region D4 ATP_bind_1 PF03029.17 EGE08764.1 - 0.43 10.3 11.0 20 4.9 0.1 5.8 7 0 0 7 7 5 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGE08764.1 - 0.59 9.7 8.2 27 4.3 0.0 4.9 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 EGE08764.1 - 0.78 9.1 6.2 28 4.1 0.2 4.8 5 0 0 5 5 5 0 Chromatin associated protein KTI12 Ras PF00071.22 EGE08764.1 - 1 9.0 3.0 71 3.0 0.0 4.3 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.20 EGE08765.1 - 2.7e-74 250.6 27.9 1.9e-68 231.3 18.0 2.6 2 1 1 3 3 3 2 Voltage gated chloride channel P5CR_dimer PF14748.6 EGE08766.1 - 1.7e-31 108.5 3.3 2.8e-31 107.8 3.3 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGE08766.1 - 2.6e-09 37.5 0.0 1.1e-06 29.1 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent CTK3 PF12243.8 EGE08767.1 - 4.8e-49 165.5 0.1 6.7e-49 165.0 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EGE08767.1 - 1.1e-20 73.5 12.7 1.3e-20 73.3 11.2 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus DUF4240 PF14024.6 EGE08767.1 - 0.03 14.5 0.5 0.95 9.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) DUF4194 PF13835.6 EGE08767.1 - 0.074 12.8 0.7 5 6.8 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4194) CARD PF00619.21 EGE08767.1 - 0.099 12.7 0.3 0.4 10.8 0.1 2.1 2 1 0 3 3 3 0 Caspase recruitment domain U3_snoRNA_assoc PF08297.11 EGE08768.1 - 1.2e-08 35.6 1.1 1.2e-08 35.6 1.1 3.7 2 2 0 2 2 2 1 U3 snoRNA associated Nop53 PF07767.11 EGE08768.1 - 0.00035 20.1 24.5 0.00051 19.5 24.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Borrelia_P83 PF05262.11 EGE08768.1 - 0.017 13.7 15.0 0.018 13.5 15.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 EGE08768.1 - 0.17 9.0 8.7 0.17 8.9 8.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 EGE08768.1 - 0.31 9.5 9.6 0.33 9.5 9.6 1.1 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 EGE08768.1 - 1.5 9.4 8.4 2 8.9 8.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein V_ATPase_I PF01496.19 EGE08768.1 - 8.1 4.2 7.3 10 3.9 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HNH_2 PF13391.6 EGE08769.1 - 4.5e-11 42.7 0.0 1.1e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease DUF155 PF02582.14 EGE08772.1 - 1.6e-51 174.9 0.2 2.3e-51 174.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Trypsin_2 PF13365.6 EGE08774.1 - 7.2e-06 27.0 0.3 0.00011 23.1 0.2 2.6 1 1 1 2 2 2 1 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EGE08774.1 - 0.00061 18.4 0.1 0.012 14.1 0.1 2.1 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.13 EGE08774.1 - 0.041 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.21 EGE08774.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 EGE08774.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase S46 p450 PF00067.22 EGE08776.1 - 3.8e-25 88.6 0.0 4.5e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ca_chan_IQ PF08763.11 EGE08776.1 - 0.0019 18.4 0.0 0.0058 16.8 0.0 1.8 1 0 0 1 1 1 1 Voltage gated calcium channel IQ domain Lon_C PF05362.13 EGE08777.1 - 4.6e-64 215.7 0.0 9.8e-64 214.7 0.0 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGE08777.1 - 3.8e-15 56.5 0.0 7.4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EGE08777.1 - 1e-06 28.6 0.0 3.3e-06 27.0 0.0 1.9 3 0 0 3 3 3 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGE08777.1 - 0.003 17.7 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) F-box-like_2 PF13013.6 EGE08777.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Pkinase PF00069.25 EGE08780.1 - 3.7e-11 42.9 0.0 1.4e-09 37.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08780.1 - 8.5e-10 38.3 0.0 1.3e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Mob1_phocein PF03637.17 EGE08781.1 - 3.2e-23 82.6 0.3 1.1e-22 80.8 0.0 1.8 2 0 0 2 2 2 1 Mob1/phocein family Chorion_2 PF03964.15 EGE08781.1 - 0.064 14.1 0.2 0.064 14.1 0.2 1.8 2 0 0 2 2 2 0 Chorion family 2 CxC6 PF18721.1 EGE08781.1 - 0.62 10.4 5.1 1.2 9.4 5.1 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 EGE08782.1 - 2.4e-48 164.1 0.4 4e-48 163.3 0.4 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGE08782.1 - 6.6e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGE08782.1 - 7.4e-05 22.7 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EGE08782.1 - 0.00078 19.3 0.1 0.0029 17.4 0.0 2.0 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGE08782.1 - 0.0018 18.0 0.0 0.94 9.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGE08782.1 - 0.0024 18.4 0.0 0.04 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGE08782.1 - 0.0062 16.9 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EGE08782.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TsaE PF02367.17 EGE08782.1 - 0.0084 16.1 0.0 0.28 11.2 0.0 2.6 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EGE08782.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EGE08782.1 - 0.02 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGE08782.1 - 0.047 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Auxin_BP PF02041.16 EGE08782.1 - 0.047 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Auxin binding protein CDCA PF18484.1 EGE08782.1 - 0.05 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat AAA_23 PF13476.6 EGE08782.1 - 0.073 13.6 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGE08782.1 - 0.08 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGE08782.1 - 0.084 12.1 0.0 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 EGE08782.1 - 0.11 12.3 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EGE08782.1 - 0.12 12.4 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGE08782.1 - 0.17 11.7 0.1 1.1 9.1 0.0 2.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain HAUS6_N PF14661.6 EGE08783.1 - 1.6e-42 145.7 0.1 1.6e-42 145.7 0.1 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.6 EGE08784.1 - 9.9e-49 165.4 0.1 1.2e-48 165.2 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGE08784.1 - 4.5e-13 49.3 0.1 6.4e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGE08784.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.7 1 1 0 1 1 1 0 HD domain HATPase_c_4 PF13749.6 EGE08784.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal Rad4 PF03835.15 EGE08785.1 - 3.9e-31 107.7 1.6 5.8e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EGE08785.1 - 9.2e-29 99.7 0.2 1.9e-28 98.7 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EGE08785.1 - 1.4e-16 61.1 1.6 3.3e-16 60.0 0.1 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EGE08785.1 - 2e-14 53.2 0.3 6.4e-14 51.5 0.1 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EGE08785.1 - 0.0022 18.4 0.0 0.011 16.2 0.0 2.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily HIT PF01230.23 EGE08786.1 - 7.8e-23 81.1 0.3 1.3e-22 80.3 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EGE08786.1 - 1.1e-05 25.9 0.0 2.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EGE08786.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 GalP_UDP_tr_C PF02744.17 EGE08786.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Methyltransf_11 PF08241.12 EGE08787.1 - 1.1e-23 83.7 0.0 1.8e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08787.1 - 5.1e-22 78.4 0.0 9.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08787.1 - 2.6e-13 50.1 0.0 3.9e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE08787.1 - 4.7e-12 46.5 0.0 9.2e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08787.1 - 7.9e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE08787.1 - 3.7e-10 39.5 0.0 5.7e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGE08787.1 - 5.4e-05 22.8 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGE08787.1 - 0.00021 21.3 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGE08787.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EGE08787.1 - 0.003 16.7 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 EGE08787.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EGE08787.1 - 0.016 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 EGE08787.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase TehB PF03848.14 EGE08787.1 - 0.063 12.7 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 EGE08787.1 - 0.074 14.1 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EGE08787.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CoA_binding_2 PF13380.6 EGE08789.1 - 1.4e-27 96.5 0.0 1.6e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain MFS_1 PF07690.16 EGE08791.1 - 1.8e-39 135.7 25.7 1.8e-39 135.7 25.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 EGE08792.1 - 2.3e-76 257.1 0.0 2.9e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE08792.1 - 9.6e-12 45.7 0.7 2.2e-11 44.5 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 EGE08793.1 - 1.2e-29 103.5 0.0 9.5e-29 100.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08793.1 - 5.2e-11 42.3 0.0 6.1e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sugar_tr PF00083.24 EGE08796.1 - 8.3e-22 77.7 24.2 9e-12 44.6 7.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Ferritin_2 PF13668.6 EGE08797.1 - 5.5e-12 46.0 0.1 1.1e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain Retinal PF15449.6 EGE08797.1 - 8.9 3.9 10.5 15 3.2 10.5 1.2 1 0 0 1 1 1 0 Retinal protein Acetyltransf_1 PF00583.25 EGE08798.1 - 3.2e-08 33.8 0.8 3.6e-08 33.6 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGE08798.1 - 8.5e-08 32.2 0.0 2.5e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGE08798.1 - 8.3e-06 26.1 0.3 2e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF905 PF06006.12 EGE08798.1 - 0.16 12.0 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) FR47 PF08445.10 EGE08798.1 - 0.17 11.9 0.0 0.84 9.7 0.0 2.2 2 1 0 2 2 2 0 FR47-like protein NIBRIN_BRCT_II PF16508.5 EGE08799.1 - 1.6e-29 102.7 0.0 3.1e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein IMS PF00817.20 EGE08800.1 - 4.7e-42 143.5 0.8 1.1e-41 142.4 0.3 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EGE08800.1 - 1.1e-13 51.9 0.2 2.9e-13 50.6 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EGE08800.1 - 3.5e-05 23.9 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DnaJ-X PF14308.6 EGE08802.1 - 3.7e-66 222.6 5.8 3.7e-66 222.6 5.8 3.6 3 2 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGE08802.1 - 4e-25 87.7 0.3 1e-24 86.4 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Condensin2nSMC PF12422.8 EGE08802.1 - 0.034 14.3 0.2 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit OrfB_IS605 PF01385.19 EGE08802.1 - 0.24 11.6 2.2 0.63 10.3 2.2 1.7 1 0 0 1 1 1 0 Probable transposase Amidohydro_1 PF01979.20 EGE08803.1 - 9.8e-10 38.3 0.3 2.1e-09 37.2 0.3 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EGE08803.1 - 5.1e-08 33.1 0.0 8.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 EGE08803.1 - 0.0024 18.4 0.2 0.032 14.7 0.1 2.5 2 1 1 3 3 3 1 CoA binding domain Miff PF05644.11 EGE08804.1 - 0.04 13.5 5.6 0.066 12.8 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Dicty_REP PF05086.12 EGE08804.1 - 0.093 10.7 9.9 0.13 10.3 9.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 EGE08804.1 - 0.19 10.9 17.7 0.3 10.3 17.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 EGE08804.1 - 0.21 11.5 12.6 1.4 8.8 12.6 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGE08804.1 - 0.66 8.6 4.5 0.41 9.3 3.0 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3439 PF11921.8 EGE08804.1 - 3.6 7.6 7.2 8.6 6.3 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NST1 PF13945.6 EGE08804.1 - 8.7 6.4 10.1 17 5.5 10.1 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator F-box-like PF12937.7 EGE08805.1 - 0.0044 16.9 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 F-box-like Mannosyl_trans PF05007.13 EGE08806.1 - 1.2e-78 264.6 10.3 1.9e-78 263.9 10.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGE08806.1 - 8.6e-12 44.8 0.6 8.6e-12 44.8 0.6 2.3 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EGE08806.1 - 7.6e-05 22.5 7.5 7.6e-05 22.5 7.5 2.9 3 1 0 3 3 3 1 Glycosyltransferase family 87 Translin PF01997.16 EGE08807.1 - 6.4e-61 205.9 0.1 7.9e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 EGE08807.1 - 0.058 14.0 0.0 0.19 12.4 0.0 1.8 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain NPV_P10 PF05531.12 EGE08807.1 - 0.21 12.1 0.9 8.6 6.9 0.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RPEL PF02755.15 EGE08808.1 - 3.9e-27 93.1 2.8 1.5e-07 30.9 0.1 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 EGE08808.1 - 0.0081 16.7 0.4 0.036 14.6 0.1 1.9 1 1 1 2 2 2 1 PPIC-type PPIASE domain Metallophos_2 PF12850.7 EGE08809.1 - 5.7e-05 23.4 0.0 0.00019 21.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGE08809.1 - 0.035 14.6 1.3 0.094 13.2 0.3 1.9 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase P2_N PF18628.1 EGE08810.1 - 0.041 13.6 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain PIN_4 PF13638.6 EGE08811.1 - 2.2e-05 24.8 0.1 0.013 15.7 0.0 2.7 2 2 1 3 3 3 2 PIN domain NYN_YacP PF05991.11 EGE08811.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 YacP-like NYN domain Rhodanese PF00581.20 EGE08812.1 - 1.9e-19 70.2 0.0 8.9e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain potato_inhibit PF00280.18 EGE08812.1 - 0.1 13.3 0.0 32 5.3 0.0 2.6 2 0 0 2 2 2 0 Potato inhibitor I family zf-ANAPC11 PF12861.7 EGE08813.1 - 1.7e-45 153.0 9.5 2.2e-45 152.6 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGE08813.1 - 7.9e-22 77.3 9.9 1.1e-21 76.8 9.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGE08813.1 - 3.2e-08 33.8 14.4 7.4e-07 29.4 14.4 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE08813.1 - 5.2e-05 23.0 4.1 5.2e-05 23.0 4.1 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE08813.1 - 0.00011 22.2 8.4 0.00014 21.8 5.0 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGE08813.1 - 0.0004 20.2 12.2 0.0014 18.4 12.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE08813.1 - 0.0033 17.3 6.4 0.0033 17.3 6.4 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGE08813.1 - 0.017 14.9 11.3 0.64 9.9 8.2 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGE08813.1 - 0.034 14.1 15.4 0.32 11.0 15.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGE08813.1 - 0.079 12.6 12.7 0.14 11.8 10.9 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGE08813.1 - 0.15 11.8 9.1 1.1 9.0 9.1 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGE08813.1 - 0.17 12.1 11.3 0.17 12.1 8.7 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EGE08813.1 - 0.28 11.4 16.6 4.9 7.4 16.6 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EGE08813.1 - 0.56 10.1 4.2 0.96 9.3 4.2 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pellino PF04710.14 EGE08813.1 - 0.68 8.5 3.9 0.2 10.3 0.8 1.6 1 1 0 1 1 1 0 Pellino PHD PF00628.29 EGE08813.1 - 0.75 9.7 12.3 2.9 7.9 12.3 2.0 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 EGE08813.1 - 3 8.0 11.4 2.7 8.1 5.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.6 EGE08813.1 - 4.2 7.7 10.0 1.1e+02 3.1 10.8 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.7 EGE08813.1 - 4.9 7.4 12.6 7.1 6.8 11.0 2.1 1 1 1 2 2 2 0 RING-variant domain zf-RING-like PF08746.11 EGE08813.1 - 5.6 7.4 11.3 31 5.0 11.3 2.1 1 1 0 1 1 1 0 RING-like domain Kinesin PF00225.23 EGE08815.1 - 7.5e-107 357.1 0.4 2.1e-106 355.7 0.4 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGE08815.1 - 6.7e-26 91.0 0.0 4.3e-25 88.4 0.0 2.5 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 EGE08815.1 - 4.4e-07 30.4 0.9 4.4e-07 30.4 0.9 5.1 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding UPF0183 PF03676.14 EGE08816.1 - 9.1e-64 216.2 0.0 1.3e-40 139.9 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.22 EGE08817.1 - 1.5e-162 542.0 0.0 1.9e-162 541.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGE08817.1 - 2.6e-21 76.2 0.4 5.4e-21 75.1 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGE08817.1 - 1.5e-20 73.3 0.1 2.1e-13 49.8 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGE08817.1 - 0.052 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGE08817.1 - 0.066 12.5 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 EGE08817.1 - 9.5 6.2 8.7 35 4.4 8.7 1.9 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Bac_rhodopsin PF01036.18 EGE08818.1 - 2.2e-38 132.1 17.9 2.6e-38 131.8 17.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Phage_holin_3_6 PF07332.11 EGE08818.1 - 0.0012 18.9 9.8 0.066 13.3 1.7 3.1 2 1 1 3 3 3 2 Putative Actinobacterial Holin-X, holin superfamily III DUF1345 PF07077.11 EGE08818.1 - 0.0033 17.2 8.0 0.0097 15.6 0.5 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1345) DUF3810 PF12725.7 EGE08818.1 - 0.13 11.5 13.6 0.12 11.7 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2391 PF09622.10 EGE08818.1 - 0.14 11.4 5.6 0.071 12.4 1.8 2.0 1 1 1 2 2 2 0 Putative integral membrane protein (DUF2391) Glycos_transf_4 PF00953.21 EGE08818.1 - 0.24 11.4 13.1 0.26 11.2 9.0 2.5 1 1 1 2 2 2 0 Glycosyl transferase family 4 DUF3938 PF13074.6 EGE08818.1 - 1.6 9.0 13.2 0.086 13.1 2.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3938) Ribosomal_S5 PF00333.20 EGE08820.1 - 1.3e-27 95.6 2.1 9.2e-27 92.8 1.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGE08820.1 - 9.9e-22 76.2 0.0 1.6e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EGE08820.1 - 2.6 8.6 11.0 6.2 7.4 11.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mpv17_PMP22 PF04117.12 EGE08821.1 - 1.8e-21 76.1 0.3 2.9e-21 75.5 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family IF4E PF01652.18 EGE08822.1 - 2.5e-52 176.9 1.7 3.2e-52 176.5 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 EGE08823.1 - 2.1e-62 211.1 0.0 5.2e-62 209.8 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGE08823.1 - 1.6e-11 45.0 0.0 2.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 EGE08824.1 - 1.6e-29 102.0 2.1 2e-29 101.7 2.1 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.11 EGE08824.1 - 0.0089 16.7 0.1 0.012 16.3 0.1 1.3 1 1 0 1 1 1 1 Replication protein A C terminal Syntaxin PF00804.25 EGE08825.1 - 1.5e-17 63.9 12.1 1.5e-17 63.9 12.1 1.9 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 EGE08825.1 - 1.7e-08 34.7 6.7 8.1e-08 32.6 0.5 2.7 2 1 1 3 3 3 1 Syntaxin-like protein Use1 PF09753.9 EGE08825.1 - 2.9e-06 27.2 5.3 4.4e-06 26.6 5.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 EGE08825.1 - 1.9e-05 24.5 17.6 0.00023 21.1 15.8 3.1 2 1 0 2 2 2 1 SNARE domain Spectrin PF00435.21 EGE08825.1 - 0.0041 17.6 7.6 0.57 10.7 0.0 3.3 3 1 0 3 3 3 2 Spectrin repeat MCU PF04678.13 EGE08825.1 - 0.0044 17.1 0.6 0.0044 17.1 0.6 2.5 2 1 0 2 2 2 1 Mitochondrial calcium uniporter COG2 PF06148.11 EGE08825.1 - 0.01 15.9 0.2 0.01 15.9 0.2 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TRP PF06011.12 EGE08825.1 - 0.021 13.6 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF2207 PF09972.9 EGE08825.1 - 0.027 13.2 0.0 0.048 12.4 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 EGE08825.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SP_C-Propep PF08999.10 EGE08825.1 - 0.074 12.8 2.5 0.13 12.1 2.5 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Gp-FAR-1 PF05823.12 EGE08825.1 - 0.086 13.2 4.4 1.7 9.0 3.1 2.4 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Orf78 PF06024.12 EGE08825.1 - 0.092 13.1 0.4 0.092 13.1 0.4 2.2 2 1 0 2 2 2 0 Orf78 (ac78) DUF5345 PF17280.2 EGE08825.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.1 2 0 0 2 2 1 0 Family of unknown function (DUF5345) MT0933_antitox PF14013.6 EGE08825.1 - 0.13 12.6 0.7 0.55 10.6 0.2 2.3 2 0 0 2 2 2 0 MT0933-like antitoxin protein PBP1_TM PF14812.6 EGE08825.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.6 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_F PF12259.8 EGE08825.1 - 0.16 10.4 0.1 0.16 10.4 0.1 2.7 1 1 2 3 3 3 0 Baculovirus F protein Syntaxin-6_N PF09177.11 EGE08825.1 - 0.17 12.5 9.8 0.14 12.8 1.6 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CENP-H PF05837.12 EGE08825.1 - 0.2 12.1 10.0 1.1 9.7 0.4 2.7 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fusion_F0 PF13044.6 EGE08825.1 - 0.28 9.8 1.9 0.55 8.8 1.9 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Pox_EPC_I2-L1 PF12575.8 EGE08825.1 - 0.3 11.3 1.9 0.83 9.9 1.9 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Baculo_11_kDa PF06143.11 EGE08825.1 - 0.37 10.4 5.4 1.3 8.6 5.4 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family Fib_alpha PF08702.10 EGE08825.1 - 0.69 10.1 12.2 0.72 10.0 0.8 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family zf-CpG_bind_C PF12269.8 EGE08825.1 - 0.71 9.6 8.7 2 8.1 0.8 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain YtxH PF12732.7 EGE08825.1 - 1.1 9.9 3.3 1.1e+02 3.5 3.3 3.0 1 1 0 1 1 1 0 YtxH-like protein BLOC1_2 PF10046.9 EGE08825.1 - 1.5 9.2 5.1 4.4 7.7 0.7 3.2 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ISG65-75 PF11727.8 EGE08825.1 - 2.4 7.3 8.8 11 5.1 2.6 2.5 2 1 1 3 3 3 0 Invariant surface glycoprotein DUF4407 PF14362.6 EGE08825.1 - 3.9 6.7 12.9 39 3.5 12.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 EGE08825.1 - 5.6 7.4 6.5 1.5 9.2 0.2 2.8 3 0 0 3 3 2 0 TSC-22/dip/bun family TMPIT PF07851.13 EGE08825.1 - 6.8 5.8 9.1 4.5 6.4 0.6 2.3 1 1 1 2 2 2 0 TMPIT-like protein zf-C4H2 PF10146.9 EGE08825.1 - 8.6 6.6 12.1 10 6.4 1.0 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein NAPRTase PF04095.16 EGE08827.1 - 4.6e-56 190.1 0.1 2.1e-28 99.6 0.2 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EGE08827.1 - 9e-35 119.8 0.2 2e-34 118.7 0.2 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain bZIP_2 PF07716.15 EGE08829.1 - 0.029 14.4 6.1 0.045 13.8 6.1 1.2 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EGE08829.1 - 0.031 14.4 7.3 0.05 13.7 7.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor Aminotran_4 PF01063.19 EGE08831.1 - 7.3e-36 124.1 0.0 9.5e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EGE08832.1 - 0.00051 19.5 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M49 PF03571.15 EGE08833.1 - 6.5e-246 817.0 0.0 9.9e-246 816.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M49 PAD_porph PF04371.15 EGE08833.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase DUF3060 PF11259.8 EGE08834.1 - 0.014 15.1 0.5 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) Senescence_reg PF04520.13 EGE08834.1 - 1.8 9.3 6.2 12 6.7 6.2 2.1 1 1 0 1 1 1 0 Senescence regulator SNF5 PF04855.12 EGE08836.1 - 9.4e-82 274.4 0.0 1.2e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EGE08836.1 - 0.011 15.4 4.6 0.028 14.0 4.6 1.8 1 0 0 1 1 1 0 GATA zinc finger Rubredoxin_2 PF18073.1 EGE08836.1 - 3.6 7.4 10.7 1 9.2 1.0 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain BHD_1 PF10403.9 EGE08839.1 - 0.011 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 WD40 PF00400.32 EGE08840.1 - 4.4e-22 78.0 27.3 5.3e-06 27.1 0.2 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08840.1 - 1.4e-11 44.5 8.0 0.00013 22.2 0.2 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EGE08840.1 - 0.00062 19.7 10.7 0.042 13.8 1.9 2.8 1 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term Ank_2 PF12796.7 EGE08841.1 - 7.3e-33 113.0 4.1 5.5e-10 39.7 0.0 4.3 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08841.1 - 9.3e-26 89.9 6.4 5.5e-09 36.4 0.0 6.3 2 1 6 8 8 8 5 Ankyrin repeats (many copies) SPX PF03105.19 EGE08841.1 - 4.3e-18 66.4 20.5 3.6e-08 33.7 0.2 3.9 2 2 2 4 4 4 3 SPX domain Ank_3 PF13606.6 EGE08841.1 - 2.7e-16 58.0 4.8 0.06 13.9 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat GDPD PF03009.17 EGE08841.1 - 4.1e-15 56.2 0.0 1.9e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 EGE08841.1 - 1.2e-12 47.8 2.8 0.14 12.5 0.0 5.8 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGE08841.1 - 3.6e-08 33.5 8.9 0.16 12.5 0.1 6.9 7 0 0 7 7 7 3 Ankyrin repeat SKG6 PF08693.10 EGE08842.1 - 1.7e-08 33.7 6.2 3.2e-08 32.8 6.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EGE08842.1 - 0.0026 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) ASFV_J13L PF05568.11 EGE08842.1 - 0.0063 16.3 0.8 0.0063 16.3 0.8 2.8 2 1 1 4 4 3 1 African swine fever virus J13L protein DUF2207 PF09972.9 EGE08842.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mem_trans PF03547.18 EGE08842.1 - 0.098 11.0 0.0 0.2 10.0 0.0 1.4 2 0 0 2 2 2 0 Membrane transport protein Adeno_E3_CR2 PF02439.15 EGE08842.1 - 0.1 12.4 0.8 0.18 11.6 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EGE08842.1 - 0.13 13.2 0.4 0.31 11.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1970 PF09301.10 EGE08842.1 - 0.22 11.8 1.2 0.28 11.4 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1970) MLANA PF14991.6 EGE08842.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 2 0 Protein melan-A DUF2615 PF11027.8 EGE08842.1 - 3.4 7.9 0.0 3.4 7.9 0.0 3.7 3 1 1 4 4 2 0 Protein of unknown function (DUF2615) DUF2681 PF10883.8 EGE08842.1 - 4.7 7.7 5.4 2.9 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SKG6 PF08693.10 EGE08843.1 - 0.035 13.5 0.4 0.067 12.6 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Sugar_tr PF00083.24 EGE08844.1 - 1.5e-98 330.6 19.4 4.1e-98 329.2 19.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE08844.1 - 2.4e-30 105.6 21.3 2.4e-30 105.6 21.3 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EGE08845.1 - 6.8e-39 133.8 39.2 6.8e-39 133.8 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08845.1 - 1e-09 37.8 7.9 1e-09 37.8 7.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Guanylate_kin PF00625.21 EGE08846.1 - 4.6e-12 46.0 0.0 7.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase ABC_tran PF00005.27 EGE08847.1 - 6.7e-46 156.2 0.9 4.7e-22 79.0 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EGE08847.1 - 1.9e-21 75.9 6.5 1.9e-21 75.9 6.5 3.7 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 EGE08847.1 - 3.2e-17 63.3 1.8 0.0021 17.9 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGE08847.1 - 1.1e-11 44.6 0.2 0.0051 16.3 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE08847.1 - 4.6e-06 26.9 0.0 0.012 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGE08847.1 - 7.3e-06 26.0 0.0 0.11 12.6 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGE08847.1 - 9.4e-06 26.1 0.4 0.2 12.0 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGE08847.1 - 1.1e-05 26.0 17.7 0.015 15.8 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EGE08847.1 - 2.4e-05 24.0 0.2 0.27 11.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EGE08847.1 - 3.7e-05 23.5 0.0 0.0047 16.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGE08847.1 - 4.6e-05 23.4 2.2 0.091 12.7 0.1 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 EGE08847.1 - 6.4e-05 23.1 1.5 0.53 10.4 0.1 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGE08847.1 - 0.00028 21.4 6.0 0.37 11.3 0.0 3.8 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 EGE08847.1 - 0.00034 20.4 1.2 0.88 9.2 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EGE08847.1 - 0.00073 19.3 15.9 0.24 11.0 0.0 5.0 4 1 0 5 5 5 2 AAA ATPase domain AAA_28 PF13521.6 EGE08847.1 - 0.00076 19.8 3.4 0.3 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EGE08847.1 - 0.0023 18.4 0.1 1.1 9.7 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGE08847.1 - 0.0033 17.4 0.2 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 EGE08847.1 - 0.0036 16.9 0.1 3.7 7.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EGE08847.1 - 0.011 15.0 2.2 1.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 EGE08847.1 - 0.014 15.8 0.1 9.2 6.7 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 EGE08847.1 - 0.015 15.4 7.2 2 8.4 0.0 4.0 4 1 0 4 4 4 0 Dynamin family Peripla_BP_3 PF13377.6 EGE08847.1 - 0.016 15.5 0.1 25 5.1 0.0 3.4 3 0 0 3 3 3 0 Periplasmic binding protein-like domain AAA_14 PF13173.6 EGE08847.1 - 0.022 14.8 0.6 14 5.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 EGE08847.1 - 0.027 14.4 0.6 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGE08847.1 - 0.027 14.4 0.1 1.8 8.5 0.1 2.9 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EGE08847.1 - 0.034 13.7 0.6 2.3 7.8 0.5 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EGE08847.1 - 0.034 14.0 0.0 1 9.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EGE08847.1 - 0.035 13.1 4.2 1.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 EGE08847.1 - 0.047 13.9 0.1 8.8 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EGE08847.1 - 0.048 13.3 0.2 3.2 7.3 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2813 PF11398.8 EGE08847.1 - 0.051 12.8 1.1 0.21 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_5 PF07728.14 EGE08847.1 - 0.095 12.7 0.5 17 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3385 PF11865.8 EGE08847.1 - 0.11 12.4 0.4 0.35 10.8 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) AAA_7 PF12775.7 EGE08847.1 - 0.13 11.7 0.1 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Bact_transglu_N PF08379.10 EGE08848.1 - 0.67 10.9 0.0 0.67 10.9 0.0 3.6 4 0 0 4 4 4 0 Bacterial transglutaminase-like N-terminal region DUF1279 PF06916.13 EGE08849.1 - 1.6e-25 89.5 0.0 2.2e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Innate_immun PF12782.7 EGE08849.1 - 0.18 11.3 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Ribosomal_L3 PF00297.22 EGE08850.1 - 2.8e-16 59.5 4.0 2.1e-14 53.3 0.5 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 EGE08851.1 - 1.1e-43 147.7 0.0 1.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF4271 PF14093.6 EGE08852.1 - 0.011 15.6 1.1 0.21 11.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF3784 PF12650.7 EGE08852.1 - 0.013 15.7 0.1 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) OPT PF03169.15 EGE08852.1 - 0.069 11.8 1.0 0.088 11.4 1.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4282 PF14110.6 EGE08852.1 - 4.2 8.2 6.7 16 6.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) JmjC PF02373.22 EGE08853.1 - 2.5e-08 34.3 0.8 6.1e-07 29.9 0.8 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGE08853.1 - 3.3e-06 27.2 8.2 3.3e-06 27.2 8.2 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EGE08853.1 - 0.0094 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zinc_ribbon_15 PF17032.5 EGE08853.1 - 1.4 9.8 14.9 1.4 9.8 2.0 3.4 3 0 0 3 3 3 0 zinc-ribbon family UbiA PF01040.18 EGE08854.1 - 1.6e-42 145.5 17.1 2.3e-42 145.0 17.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Flavoprotein PF02441.19 EGE08855.1 - 3.3e-44 150.4 0.0 4.8e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 EGE08856.1 - 5.4e-15 55.4 0.0 9.3e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Phasin PF05597.11 EGE08857.1 - 0.081 12.9 0.1 0.081 12.9 0.1 2.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CCDC23 PF15674.5 EGE08857.1 - 0.15 12.0 16.4 0.081 12.9 7.3 2.7 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 23 FliD_C PF07195.12 EGE08857.1 - 1.5 8.2 8.0 8.3 5.8 2.2 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CTP_transf_like PF01467.26 EGE08858.1 - 2.5e-25 89.3 0.0 4.9e-22 78.7 0.0 3.8 3 1 0 4 4 4 2 Cytidylyltransferase-like PRELI PF04707.14 EGE08860.1 - 3.8e-45 153.5 0.4 4.5e-45 153.3 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family PXA PF02194.15 EGE08861.1 - 1.7e-32 112.9 0.0 3.3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EGE08861.1 - 2.4e-23 82.8 0.0 8.9e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EGE08861.1 - 3.4e-10 39.9 0.0 7.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 PX domain Mito_carr PF00153.27 EGE08862.1 - 8.2e-73 240.4 1.4 2.1e-23 82.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGE08862.1 - 0.00028 20.1 0.7 0.017 14.3 0.0 3.0 2 1 2 4 4 4 2 Gammaproteobacterial serine protease RRM_1 PF00076.22 EGE08863.1 - 2.5e-12 46.4 0.0 3.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE08863.1 - 0.00039 20.4 0.0 0.00054 19.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sedlin_N PF04628.13 EGE08864.1 - 1.7e-15 57.3 0.0 3.2e-15 56.4 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L18 PF17135.4 EGE08865.1 - 8.2e-95 315.5 2.2 9.1e-95 315.4 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGE08865.1 - 1.6e-05 25.5 0.1 0.0001 23.0 0.1 2.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AAA_19 PF13245.6 EGE08865.1 - 0.051 13.9 0.0 0.069 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aldedh PF00171.22 EGE08866.1 - 3.1e-10 39.2 7.0 4.6e-09 35.3 4.7 2.6 1 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGE08866.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) PCI PF01399.27 EGE08867.1 - 6.7e-05 23.3 0.1 0.00018 22.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain HrpB1_HrpK PF09613.10 EGE08867.1 - 0.081 12.6 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) NifU_N PF01592.16 EGE08868.1 - 2.1e-50 170.2 0.0 2.7e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EGE08868.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain UDG PF03167.19 EGE08869.1 - 2.3e-22 79.6 0.1 4.7e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Mucin PF01456.17 EGE08869.1 - 1.4 8.9 25.7 0.68 9.9 17.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein UCH PF00443.29 EGE08871.1 - 3.4e-36 125.1 0.0 4.8e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGE08871.1 - 3.9e-25 87.4 2.0 3.7e-23 81.0 0.4 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 EGE08871.1 - 1.4e-23 83.0 15.2 1.2e-19 70.3 1.4 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGE08871.1 - 1.3e-15 57.9 1.5 2.6e-13 50.3 0.0 3.4 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EGE08871.1 - 1.8e-14 53.3 0.1 4.3e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 EGE08871.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain FtsJ PF01728.19 EGE08872.1 - 7.7e-56 189.0 0.0 9.2e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EGE08872.1 - 1.7e-05 24.7 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08872.1 - 0.00071 19.4 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF2875 PF11394.8 EGE08872.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) ATG7_N PF16420.5 EGE08873.1 - 3.8e-109 365.0 0.0 4.9e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGE08873.1 - 2.3e-42 145.0 0.0 3.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 EGE08873.1 - 0.013 15.2 0.0 0.08 12.6 0.0 2.3 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EGE08873.1 - 0.027 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGE08873.1 - 0.056 12.8 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.23 EGE08874.1 - 2.8e-28 97.7 2.1 4.4e-28 97.1 2.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGE08874.1 - 3.8e-12 46.1 0.5 9.8e-12 44.8 0.3 1.7 2 0 0 2 2 2 1 MafB19-like deaminase AAA_18 PF13238.6 EGE08874.1 - 0.012 16.1 0.0 0.15 12.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain CoaE PF01121.20 EGE08874.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase SNAD4 PF18750.1 EGE08874.1 - 0.11 12.6 0.2 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 His_biosynth PF00977.21 EGE08875.1 - 8.2e-47 159.6 1.1 2.6e-46 157.9 1.1 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EGE08875.1 - 2.3e-25 89.5 0.0 3.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGE08875.1 - 8.2e-12 45.4 0.0 3.2e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGE08875.1 - 1.3e-09 37.9 0.0 2.9e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGE08875.1 - 0.00032 20.5 0.1 0.0069 16.2 0.0 2.3 2 0 0 2 2 2 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 EGE08875.1 - 0.05 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 DNA_pol_E_B PF04042.16 EGE08876.1 - 4.2e-50 170.0 0.1 6.2e-50 169.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TPR_12 PF13424.6 EGE08877.1 - 0.00016 21.9 0.9 0.00023 21.4 0.9 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 EGE08877.1 - 0.0014 18.6 1.6 0.0025 17.8 1.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EGE08877.1 - 0.023 15.3 1.8 0.089 13.5 0.9 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EGE08877.1 - 0.14 12.2 0.7 0.14 12.2 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGE08877.1 - 0.17 12.3 0.6 1.2 9.7 0.1 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGE08877.1 - 0.33 11.2 5.0 0.26 11.5 1.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08877.1 - 0.73 9.6 4.4 9.2 6.0 1.5 2.3 2 0 0 2 2 2 0 TPR repeat Pex14_N PF04695.13 EGE08878.1 - 0.022 15.4 0.6 0.037 14.7 0.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 EGE08878.1 - 0.066 13.4 1.3 0.099 12.8 1.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 EGE08878.1 - 1.3 7.8 5.0 1.6 7.4 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EGE08878.1 - 1.9 6.7 6.2 2.8 6.1 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EGE08878.1 - 9 6.0 10.6 13 5.5 10.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-sulfurylase PF01747.17 EGE08881.1 - 1.8e-72 243.3 0.0 2.6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EGE08881.1 - 3.4e-50 169.8 0.0 5.1e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 EGE08881.1 - 4.4e-47 159.9 0.0 7.2e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PAPS_reduct PF01507.19 EGE08885.1 - 1.2e-42 145.9 0.0 1.7e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 EGE08886.1 - 7.3e-23 81.9 0.0 1.1e-22 81.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE08886.1 - 2.3e-19 70.5 0.6 3.1e-19 70.1 0.6 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE08886.1 - 8.5e-08 32.2 0.1 1.7e-06 27.9 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGE08886.1 - 0.00019 21.6 0.1 0.0029 17.7 0.1 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EGE08886.1 - 0.0032 16.9 0.0 0.079 12.3 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 EGE08886.1 - 0.051 13.0 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 EGE08886.1 - 0.15 11.6 0.1 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase LIAS_N PF16881.5 EGE08887.1 - 2.9e-26 92.0 0.0 6.9e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EGE08887.1 - 2.3e-13 50.9 0.0 3.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 EGE08888.1 - 3.7e-11 43.4 3.7 2e-05 25.2 0.0 5.2 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08888.1 - 0.0029 17.9 0.0 16 5.9 0.0 4.6 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGE08888.1 - 0.043 13.4 0.0 6 6.4 0.0 2.7 2 1 1 3 3 3 0 PQQ-like domain Oxysterol_BP PF01237.18 EGE08888.1 - 0.087 11.6 0.4 0.14 11.0 0.4 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein PQQ_3 PF13570.6 EGE08888.1 - 0.1 13.1 0.0 13 6.4 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Gryzun-like PF12742.7 EGE08888.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Latrophilin PF02354.16 EGE08889.1 - 0.054 12.6 3.1 0.069 12.2 3.1 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region DeoC PF01791.9 EGE08890.1 - 8.6e-17 61.5 3.1 1.3e-16 60.9 3.1 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EGE08890.1 - 8.5e-05 21.9 1.5 0.00012 21.4 1.5 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EGE08890.1 - 0.016 14.7 0.5 0.032 13.7 0.5 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 EGE08890.1 - 0.076 12.0 1.8 0.098 11.7 0.9 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase ComA PF02679.15 EGE08890.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) TP_methylase PF00590.20 EGE08891.1 - 9.3e-45 153.2 0.0 1.4e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.6 EGE08891.1 - 4e-09 36.0 0.0 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 EGE08891.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding PCI PF01399.27 EGE08892.1 - 6.6e-23 81.2 0.0 1.9e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 EGE08892.1 - 1.5e-16 60.2 1.9 3.8e-16 58.9 1.9 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CK2S PF15011.6 EGE08892.1 - 0.053 13.4 0.9 4.3 7.2 0.1 2.9 2 1 0 3 3 3 0 Casein Kinase 2 substrate FSH1 PF03959.13 EGE08893.1 - 1e-66 224.6 0.0 1.5e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGE08893.1 - 0.00057 20.6 0.9 0.0016 19.1 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EGE08893.1 - 0.012 15.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 EGE08893.1 - 0.058 13.3 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EGE08893.1 - 0.12 11.6 0.1 0.37 10.0 0.0 1.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGE08893.1 - 0.15 11.8 0.1 11 5.7 0.1 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EGE08893.1 - 0.2 11.1 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Ribosomal_S27e PF01667.17 EGE08897.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 EGE08897.1 - 0.26 11.3 6.1 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CDP-OH_P_transf PF01066.21 EGE08899.1 - 2.3e-17 63.5 0.0 2.3e-17 63.5 0.0 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NIPSNAP PF07978.13 EGE08900.1 - 2.9e-41 139.8 0.4 1.3e-29 102.4 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP MSA-2c PF12238.8 EGE08900.1 - 0.23 11.5 8.3 0.38 10.7 8.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c SASRP1 PF15160.6 EGE08900.1 - 0.25 11.0 1.9 0.43 10.2 1.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 QWRF PF04484.12 EGE08900.1 - 8.2 6.1 8.6 57 3.3 10.0 1.6 2 0 0 2 2 2 0 QWRF family Putative_PNPOx PF01243.20 EGE08901.1 - 3.6e-12 46.3 0.0 7.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EGE08901.1 - 0.062 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Peptidase_C65 PF10275.9 EGE08902.1 - 3.5e-62 210.1 0.4 4.7e-62 209.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase C65 Otubain PCI PF01399.27 EGE08904.1 - 2.9e-16 59.9 1.1 4.7e-16 59.2 0.1 1.9 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.6 EGE08904.1 - 0.0031 17.4 0.1 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE08904.1 - 0.0048 16.5 0.3 0.049 13.3 0.1 2.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EGE08904.1 - 0.011 15.8 4.4 0.095 12.9 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGE08904.1 - 0.018 15.4 0.3 0.51 10.7 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE08904.1 - 0.026 15.3 0.1 1.3 10.0 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CorA PF01544.18 EGE08904.1 - 0.051 12.9 0.3 0.11 11.7 0.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_1 PF00515.28 EGE08904.1 - 0.056 13.3 2.5 0.37 10.7 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CWC25 PF12542.8 EGE08905.1 - 1.2e-25 90.4 0.4 1.2e-25 90.4 0.4 4.0 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGE08905.1 - 8.7e-14 51.4 10.4 8.7e-14 51.4 10.4 4.7 4 2 2 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 EGE08906.1 - 7.1e-53 178.5 0.0 8.3e-53 178.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE08906.1 - 8.6e-22 77.6 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE08906.1 - 8.7e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGE08906.1 - 6.8e-05 22.3 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGE08906.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGE08906.1 - 0.0024 17.1 0.0 0.0041 16.3 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGE08906.1 - 0.0076 16.3 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE08906.1 - 0.021 14.7 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGE08906.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGE08906.1 - 0.14 12.7 0.0 0.27 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter BPL_LplA_LipB PF03099.19 EGE08907.1 - 3.7e-06 26.9 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-box PF00646.33 EGE08908.1 - 0.0071 16.2 3.3 0.28 11.1 0.2 3.5 3 0 0 3 3 3 2 F-box domain DUF3387 PF11867.8 EGE08908.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Ank_2 PF12796.7 EGE08909.1 - 4.2e-20 72.1 2.0 8.6e-07 29.5 0.3 3.2 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE08909.1 - 1.2e-16 60.8 1.6 8.1e-07 29.5 0.4 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGE08909.1 - 6.2e-15 54.9 6.4 0.0016 18.8 0.1 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGE08909.1 - 1.2e-13 51.0 4.3 0.005 17.1 0.4 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE08909.1 - 1.3e-12 46.7 0.6 0.021 15.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat polyprenyl_synt PF00348.17 EGE08910.1 - 2.7e-67 226.5 0.0 3.4e-66 222.9 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.8 EGE08910.1 - 0.063 13.2 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Rpn3_C PF08375.11 EGE08911.1 - 9.9e-26 90.0 0.6 9.9e-26 90.0 0.6 2.3 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EGE08911.1 - 1.3e-21 77.0 0.1 6.3e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain DASH_Spc34 PF08657.10 EGE08912.1 - 1e-43 150.0 6.9 3.6e-21 76.1 4.0 2.1 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF848 PF05852.11 EGE08912.1 - 0.0041 17.2 4.6 0.0083 16.2 4.6 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) DASH_Spc19 PF08287.11 EGE08912.1 - 0.0077 16.1 3.6 0.017 15.1 3.6 1.5 1 0 0 1 1 1 1 Spc19 Rtt102p PF09510.10 EGE08912.1 - 0.13 12.4 0.6 0.26 11.5 0.6 1.4 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Prefoldin_2 PF01920.20 EGE08912.1 - 0.14 12.2 6.6 1.9 8.5 0.8 2.5 2 0 0 2 2 2 0 Prefoldin subunit VSG_B PF13206.6 EGE08912.1 - 0.15 11.3 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain ATG16 PF08614.11 EGE08912.1 - 8 6.6 13.4 46 4.1 1.6 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) F-box PF00646.33 EGE08913.1 - 0.00015 21.5 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGE08913.1 - 0.013 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like TFIID_20kDa PF03847.13 EGE08914.1 - 1.3e-23 83.2 0.0 2.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CorA PF01544.18 EGE08915.1 - 4.6e-15 55.7 1.1 8.4e-15 54.8 1.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein STE PF02200.16 EGE08915.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 STE like transcription factor DUF1203 PF06718.11 EGE08916.1 - 7.1e-37 126.2 0.0 8.8e-37 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1203) eIF2A PF08662.11 EGE08919.1 - 3.1e-84 281.7 0.1 1e-82 276.8 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EGE08919.1 - 0.016 16.0 0.8 2.1 9.3 0.1 3.9 3 1 1 4 4 4 0 WD domain, G-beta repeat NAD_binding_6 PF08030.12 EGE08920.1 - 8.7e-34 116.9 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGE08920.1 - 5.7e-23 81.1 0.0 2.5e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EGE08920.1 - 2.4e-18 66.4 8.1 2.4e-18 66.4 8.1 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EGE08920.1 - 0.041 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGE08920.1 - 0.087 13.5 0.0 0.29 11.8 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetyltransf_13 PF13880.6 EGE08922.1 - 2.3e-28 98.0 0.1 6.2e-28 96.6 0.0 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EGE08922.1 - 4.5e-13 48.8 0.5 7.7e-13 48.0 0.5 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO SSP160 PF06933.11 EGE08922.1 - 0.98 7.5 15.7 1.4 7.0 15.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Acyl-CoA_dh_N PF02771.16 EGE08923.1 - 2.2e-26 92.8 0.1 4.5e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EGE08923.1 - 1.5e-15 57.7 0.2 2.5e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGE08923.1 - 1.8e-15 56.9 0.0 3.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Pkinase PF00069.25 EGE08925.1 - 4.6e-53 180.3 0.0 1e-50 172.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE08925.1 - 1.1e-31 110.0 0.0 1.4e-30 106.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE08925.1 - 0.0027 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGE08925.1 - 0.0037 16.3 0.1 0.0055 15.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGE08925.1 - 0.005 15.9 0.1 0.0091 15.1 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGE08925.1 - 0.15 10.8 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Mem_trans PF03547.18 EGE08927.1 - 2.7e-53 180.8 0.3 3.4e-53 180.4 0.3 1.1 1 0 0 1 1 1 1 Membrane transport protein Choline_kinase PF01633.20 EGE08928.1 - 1.9e-60 204.1 0.0 3.8e-60 203.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EGE08928.1 - 6.9e-17 60.9 0.0 1.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EGE08928.1 - 0.00099 19.1 1.8 0.0011 18.9 0.2 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Abhydrolase_2 PF02230.16 EGE08929.1 - 6.4e-23 81.7 0.1 5.4e-17 62.3 0.1 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGE08929.1 - 0.0062 16.0 0.4 0.015 14.8 0.4 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGE08929.1 - 0.031 13.6 0.1 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glyco_hydro_31 PF01055.26 EGE08930.1 - 5.8e-169 562.9 0.4 8.2e-169 562.4 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGE08930.1 - 6.4e-39 132.8 0.4 1.4e-38 131.6 0.4 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGE08930.1 - 3e-15 56.3 0.2 1.1e-14 54.5 0.2 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Asp PF00026.23 EGE08932.1 - 1.2e-05 24.9 0.5 0.00018 21.0 0.5 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease EphA2_TM PF14575.6 EGE08932.1 - 0.11 13.4 0.0 0.21 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 EGE08932.1 - 0.29 11.1 2.0 1.1 9.3 2.0 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 EGE08933.1 - 2e-18 66.4 39.3 2.8e-12 46.3 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08933.1 - 3.7e-14 52.4 22.7 3.8e-13 49.1 22.7 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_92 PF07971.12 EGE08934.1 - 5.3e-137 457.5 0.2 6.6e-137 457.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EGE08934.1 - 2.4e-46 158.6 2.5 4.1e-46 157.8 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ATP-synt_G PF04718.15 EGE08936.1 - 1e-33 116.1 0.1 4e-33 114.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_zinc_N PF00107.26 EGE08937.1 - 2.5e-18 66.3 0.0 5.7e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGE08937.1 - 1.1e-16 62.1 0.0 2.3e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGE08937.1 - 6.1e-07 29.3 0.0 3.6e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_1 PF00561.20 EGE08938.1 - 2.6e-14 53.5 0.0 7.9e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGE08938.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGE08938.1 - 0.12 13.0 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PAP_central PF04928.17 EGE08939.1 - 2e-108 361.1 0.0 2.9e-108 360.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGE08939.1 - 2.4e-61 206.3 0.0 3.9e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGE08939.1 - 1.7e-12 47.5 0.0 3.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EGE08939.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Glyco_transf_20 PF00982.21 EGE08940.1 - 1.6e-170 567.9 0.0 1.8e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EGE08940.1 - 0.00059 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EGE08940.1 - 0.0019 17.8 0.1 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EGE08940.1 - 0.0076 16.0 0.2 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain adh_short_C2 PF13561.6 EGE08941.1 - 6.9e-43 146.9 2.4 8.5e-43 146.6 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE08941.1 - 1.9e-39 135.2 0.8 2.3e-39 134.9 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE08941.1 - 4.2e-11 43.1 0.3 6.5e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF429 PF04250.13 EGE08941.1 - 0.042 13.6 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Amidase PF01425.21 EGE08942.1 - 1.6e-90 304.3 0.0 2e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Amidase ZT_dimer PF16916.5 EGE08943.1 - 4.3e-05 23.6 0.1 7.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Sulfotransfer_4 PF17784.1 EGE08944.1 - 2e-56 191.2 0.0 2.3e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGE08944.1 - 0.00051 20.5 0.9 0.018 15.4 0.1 2.3 1 1 1 2 2 2 2 Sulfotransferase family Methyltransf_25 PF13649.6 EGE08945.1 - 6.6e-09 36.4 0.0 1.9e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE08945.1 - 1.1e-07 32.5 0.0 2.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE08945.1 - 2e-05 24.5 0.0 9.6e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08945.1 - 2.5e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE08945.1 - 0.00081 20.0 0.0 0.01 16.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE08945.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.8 EGE08945.1 - 0.0095 15.1 0.0 0.028 13.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase BTRD1 PF17660.1 EGE08946.1 - 9.9e-34 114.9 4.5 2.9e-15 55.8 0.2 3.0 3 0 0 3 3 3 3 Bacterial tandem repeat domain 1 rve_2 PF13333.6 EGE08946.1 - 0.0053 16.9 0.3 0.042 14.0 0.0 2.6 2 1 0 2 2 2 1 Integrase core domain FGAR-AT_linker PF18072.1 EGE08946.1 - 0.12 12.9 0.0 0.74 10.4 0.0 2.0 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain 2_5_RNA_ligase2 PF13563.6 EGE08947.1 - 4.2e-33 114.4 0.1 1.1e-32 113.1 0.1 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 EGE08947.1 - 9.6e-21 73.9 0.0 2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EGE08947.1 - 2.3e-20 73.1 0.4 5.9e-20 71.8 0.4 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 EGE08947.1 - 8.5e-07 28.7 0.7 2.6e-06 27.1 0.6 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 EGE08947.1 - 0.00057 20.1 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain LigT_PEase PF02834.16 EGE08947.1 - 0.033 14.4 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase He_PIG PF05345.12 EGE08948.1 - 0.0056 16.8 0.6 0.023 14.9 0.2 2.3 2 0 0 2 2 2 1 Putative Ig domain UTRA PF07702.13 EGE08948.1 - 0.15 11.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 UTRA domain Proteasome PF00227.26 EGE08951.1 - 1.6e-34 119.1 0.0 1.5e-32 112.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGE08951.1 - 2.9e-12 46.0 1.0 3.8e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Vps36-NZF-N PF16988.5 EGE08952.1 - 0.15 11.5 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HCMV_UL139 PF12507.8 EGE08953.1 - 0.045 14.1 1.2 0.063 13.7 1.2 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein NdhL PF10716.9 EGE08953.1 - 0.07 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit Potassium_chann PF11404.8 EGE08953.1 - 0.26 11.1 0.7 0.51 10.2 0.7 1.4 1 0 0 1 1 1 0 Potassium voltage-gated channel Iso_dh PF00180.20 EGE08954.1 - 9.1e-84 281.6 0.0 1.1e-83 281.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 EGE08955.1 - 3.2e-15 56.6 3.9 5.6e-15 55.9 3.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGE08955.1 - 2.2e-11 44.2 0.0 4.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE08955.1 - 2.3e-10 41.1 0.0 7.7e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE08955.1 - 3.8e-05 24.4 0.0 9.4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE08955.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGE08955.1 - 0.00048 19.9 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGE08955.1 - 0.0024 17.2 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGE08955.1 - 0.0046 16.8 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGE08955.1 - 0.041 13.2 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ACT_7 PF13840.6 EGE08955.1 - 0.21 11.4 0.1 0.46 10.3 0.1 1.5 1 0 0 1 1 1 0 ACT domain Erv26 PF04148.13 EGE08956.1 - 1.5e-92 309.0 0.1 1.8e-92 308.8 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Ferric_reduct PF01794.19 EGE08956.1 - 0.0056 16.8 3.8 0.083 13.0 3.8 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component RhoGAP PF00620.27 EGE08957.1 - 6.1e-40 136.5 0.0 1.4e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGE08957.1 - 2.3e-14 53.8 0.6 5.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 PH domain R_equi_Vir PF05526.11 EGE08957.1 - 0.0028 17.6 1.3 0.01 15.7 1.3 1.9 1 0 0 1 1 1 1 Rhodococcus equi virulence-associated protein PH_8 PF15409.6 EGE08957.1 - 0.0086 16.3 0.1 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Peptidase_C25 PF01364.18 EGE08957.1 - 0.034 13.4 0.5 0.063 12.5 0.5 1.3 1 0 0 1 1 1 0 Peptidase family C25 DUF4763 PF15960.5 EGE08957.1 - 3 7.1 12.6 0.016 14.5 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) MDM31_MDM32 PF08118.11 EGE08959.1 - 1.6e-249 829.0 2.0 9.7e-249 826.4 2.0 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 EGE08960.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGE08960.1 - 0.098 12.5 2.1 0.098 12.5 0.6 1.8 2 0 0 2 2 2 0 KH domain Proteasome PF00227.26 EGE08961.1 - 6.2e-32 110.6 0.1 1.6e-31 109.3 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit DUF974 PF06159.13 EGE08961.1 - 0.069 12.9 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF974) HCNGP PF07818.13 EGE08962.1 - 7.2e-32 109.9 0.3 1.6e-31 108.8 0.3 1.6 1 0 0 1 1 1 1 HCNGP-like protein Ketoacyl-synt_C PF02801.22 EGE08962.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Proteasome PF00227.26 EGE08963.1 - 3.9e-30 104.7 0.0 4.8e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Gal4_dimer PF03902.13 EGE08963.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain FAA_hydrolase PF01557.18 EGE08964.1 - 6.4e-65 218.9 0.0 8.6e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.15 EGE08965.1 - 1.9e-17 63.0 2.4 2.3e-17 62.8 2.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGE08965.1 - 3e-07 31.1 0.7 3.7e-07 30.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EGE08965.1 - 0.032 14.8 0.1 0.04 14.5 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like HSP20 PF00011.21 EGE08966.1 - 3.5e-18 65.6 0.2 3.2e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGE08966.1 - 4.1e-06 26.2 0.0 0.0067 16.0 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Bac_rhodopsin PF01036.18 EGE08969.1 - 8e-36 123.7 19.7 9.1e-36 123.5 19.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AcrZ PF10766.9 EGE08969.1 - 0.42 10.2 3.6 0.67 9.6 0.1 2.4 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ MFS_1 PF07690.16 EGE08970.1 - 8e-30 103.9 60.4 4.8e-28 98.1 40.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE08970.1 - 3.7e-08 32.7 37.5 0.00056 18.9 14.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Tubulin_2 PF13809.6 EGE08970.1 - 0.13 11.4 0.6 0.19 10.9 0.6 1.1 1 0 0 1 1 1 0 Tubulin like Sulfatase PF00884.23 EGE08972.1 - 5.1e-78 262.6 0.0 6.4e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EGE08972.1 - 2.1e-05 23.3 0.0 2.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Autophagy_act_C PF03987.15 EGE08973.1 - 8.1e-14 52.0 0.1 2.9e-13 50.2 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 EGE08974.1 - 1.6e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGE08974.1 - 0.0002 21.0 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE08974.1 - 0.0097 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGE08974.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.32 EGE08975.1 - 2.4e-16 59.8 10.8 0.00059 20.6 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE08975.1 - 1.3e-06 28.6 0.0 0.0013 19.0 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE08975.1 - 0.028 13.4 0.1 6.3 5.6 0.0 3.4 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Chi-conotoxin PF16981.5 EGE08975.1 - 0.18 12.0 0.1 0.74 10.1 0.1 2.0 1 1 0 1 1 1 0 chi-Conotoxin or t superfamily Lipase_3 PF01764.25 EGE08976.1 - 9.6e-30 103.3 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EGE08976.1 - 0.00079 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EGE08976.1 - 0.0074 16.9 0.1 0.011 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 EGE08976.1 - 0.03 14.7 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal Abhydrolase_5 PF12695.7 EGE08976.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Op_neuropeptide PF08035.11 EGE08976.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Opioids neuropeptide DUF2974 PF11187.8 EGE08976.1 - 0.12 12.0 0.0 1.7 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGE08976.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WW PF00397.26 EGE08977.1 - 1e-11 44.7 0.6 2.5e-11 43.4 0.6 1.7 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.6 EGE08977.1 - 0.036 14.1 0.0 0.036 14.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4585) PhoD PF09423.10 EGE08977.1 - 0.08 11.9 0.2 0.15 11.0 0.2 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase Fungal_trans_2 PF11951.8 EGE08978.1 - 1.4e-16 60.3 0.6 9.2e-11 41.2 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE08978.1 - 1.3e-06 28.4 2.5 3.2e-06 27.2 2.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.7 EGE08980.1 - 2.5e-134 448.7 1.0 5.9e-72 242.9 0.0 5.7 3 3 3 6 6 6 3 Proteasome stabiliser HEAT PF02985.22 EGE08980.1 - 1.4e-05 24.9 5.5 0.67 10.4 0.1 8.9 10 0 0 10 10 10 1 HEAT repeat HEAT_2 PF13646.6 EGE08980.1 - 0.00018 21.8 4.7 6.2 7.3 0.1 6.4 5 2 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EGE08980.1 - 0.0072 16.8 7.6 0.62 10.6 0.0 6.2 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGE08980.1 - 0.046 14.3 3.3 0.42 11.2 0.1 4.5 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Mito_carr PF00153.27 EGE08981.1 - 1.8e-64 213.7 0.7 2.3e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Bacteriocin_IIc PF10439.9 EGE08981.1 - 0.077 13.1 1.3 5.2 7.3 0.2 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Serine_protease PF18405.1 EGE08981.1 - 0.21 10.7 0.2 3.9 6.5 0.0 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease SNF2_N PF00176.23 EGE08982.1 - 3.1e-58 197.2 0.0 5.8e-58 196.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 EGE08982.1 - 2e-09 37.1 8.4 5.9e-09 35.6 8.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE08982.1 - 2.6e-09 36.8 8.0 9.1e-09 35.0 8.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGE08982.1 - 6.6e-08 32.3 7.7 1.9e-07 30.8 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGE08982.1 - 9e-08 32.3 10.8 2.6e-07 30.9 10.8 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGE08982.1 - 5.5e-06 26.1 8.3 1.2e-05 25.1 8.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGE08982.1 - 1.6e-05 25.1 8.0 5.3e-05 23.4 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 EGE08982.1 - 1.9e-05 25.0 0.0 6.6e-05 23.2 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGE08982.1 - 2.2e-05 24.4 4.3 3.7e-05 23.6 3.1 2.2 1 1 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 EGE08982.1 - 0.00047 20.2 0.0 0.0037 17.3 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 EGE08982.1 - 0.00048 20.0 7.1 0.0014 18.6 7.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGE08982.1 - 0.0021 18.1 7.8 0.0053 16.9 7.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EGE08982.1 - 0.014 15.3 0.4 0.041 13.8 0.4 1.8 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 EGE08982.1 - 0.16 12.0 3.8 0.39 10.8 3.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGE08982.1 - 0.18 12.0 4.9 0.47 10.6 4.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Voldacs PF03517.13 EGE08982.1 - 0.2 11.8 4.6 13 5.9 0.1 3.8 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling Zn_ribbon_17 PF17120.5 EGE08982.1 - 0.33 10.6 7.6 0.82 9.3 7.6 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EGE08982.1 - 0.34 10.7 7.4 0.91 9.4 7.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EGE08982.1 - 1.5 8.5 6.0 3.6 7.3 6.0 1.6 1 0 0 1 1 1 0 P-11 zinc finger Connexin PF00029.19 EGE08983.1 - 0.26 11.0 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Connexin DUF4551 PF15087.6 EGE08983.1 - 1.8 7.3 6.0 2.1 7.1 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 EGE08983.1 - 2.5 6.8 6.8 3 6.5 6.8 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EGE08983.1 - 7.7 6.6 7.7 17 5.5 7.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Frag1 PF10277.9 EGE08986.1 - 3.1e-38 131.5 12.5 3.6e-38 131.3 12.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4436 PF14494.6 EGE08986.1 - 0.05 12.9 1.7 0.084 12.2 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) DUF5134 PF17197.4 EGE08986.1 - 0.44 10.4 3.6 0.66 9.9 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) DUF2070 PF09843.9 EGE08986.1 - 7.1 4.8 18.4 0.11 10.8 10.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) PRA1 PF03208.19 EGE08987.1 - 1.9e-34 118.3 1.2 2.3e-34 118.1 1.2 1.1 1 0 0 1 1 1 1 PRA1 family protein p450 PF00067.22 EGE08988.1 - 4.7e-05 22.3 0.0 5.7e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_C PF13243.6 EGE08989.1 - 0.0037 16.4 0.1 0.61 9.1 0.0 2.8 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGE08989.1 - 0.019 14.1 0.0 0.56 9.2 0.0 2.6 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGE08989.1 - 1.6 8.6 3.3 49 3.8 0.1 3.4 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat p450 PF00067.22 EGE08990.1 - 1.1e-43 149.7 0.0 1.2e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGE08991.1 - 2.3e-41 142.0 0.0 2.9e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGE08993.1 - 2.6e-48 164.9 0.0 2.9e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGE08994.1 - 9e-08 31.3 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EGE08996.1 - 2.7e-28 98.8 0.0 2.3e-26 92.5 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE08996.1 - 9e-17 61.4 0.0 1.7e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE08996.1 - 5.1e-06 26.5 0.0 8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EGE08996.1 - 0.0074 16.3 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EGE08996.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Csm1_B PF18211.1 EGE08996.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Csm1 subunit domain B GDP_Man_Dehyd PF16363.5 EGE08996.1 - 0.17 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGE08996.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase_fungal PF17667.1 EGE08998.1 - 9.4e-128 426.5 0.0 1.2e-127 426.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGE08998.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-C2H2 PF00096.26 EGE08999.1 - 0.0031 17.9 0.1 0.0077 16.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE08999.1 - 0.0081 16.9 0.2 0.021 15.6 0.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EGE08999.1 - 0.072 13.4 0.2 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) THDPS_M PF14789.6 EGE08999.1 - 0.083 13.0 2.2 0.12 12.4 0.3 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase middle SesA PF17107.5 EGE09000.1 - 5.9e-30 104.0 0.8 2.3e-27 95.6 0.3 3.4 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_10 PF13374.6 EGE09000.1 - 1.3e-10 40.7 1.0 0.0033 17.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE09000.1 - 3.4e-10 40.1 1.5 1.7e-07 31.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat NB-ARC PF00931.22 EGE09000.1 - 6.4e-07 28.8 0.0 2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EGE09000.1 - 9.5e-05 22.8 3.9 0.0013 19.1 0.0 3.7 3 1 1 4 4 4 1 AAA ATPase domain TPR_7 PF13176.6 EGE09000.1 - 0.0046 16.9 0.1 4.3 7.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat HeLo PF14479.6 EGE09000.1 - 0.0053 16.6 0.8 0.019 14.8 0.0 2.3 3 1 0 3 3 3 1 Prion-inhibition and propagation TPR_19 PF14559.6 EGE09000.1 - 0.018 15.5 2.9 0.24 11.9 0.2 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat NTPase_1 PF03266.15 EGE09000.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NTPase PPR PF01535.20 EGE09000.1 - 0.061 13.6 0.1 59 4.2 0.0 3.9 4 0 0 4 4 3 0 PPR repeat TPR_20 PF14561.6 EGE09000.1 - 0.065 13.6 0.3 0.46 10.8 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGE09000.1 - 0.076 13.9 0.3 2 9.5 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2802 PF10975.8 EGE09000.1 - 0.08 13.1 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) WH1 PF00568.23 EGE09000.1 - 0.13 12.2 0.0 0.48 10.4 0.0 1.9 1 0 0 1 1 1 0 WH1 domain ANAPC3 PF12895.7 EGE09000.1 - 0.2 11.9 1.2 1.2 9.4 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CtIP_N PF10482.9 EGE09002.1 - 0.011 15.7 2.3 0.021 14.9 2.3 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2408 PF10303.9 EGE09002.1 - 0.11 13.1 0.7 0.2 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Hat1_N PF10394.9 EGE09003.1 - 3.6e-56 189.8 0.1 7.5e-56 188.8 0.1 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus UBN_AB PF14075.6 EGE09003.1 - 0.22 11.2 2.8 0.4 10.4 2.8 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF917 PF06032.12 EGE09004.1 - 1.7e-122 408.7 0.3 1.8e-121 405.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EGE09004.1 - 1.5e-28 99.7 7.8 2e-26 92.8 0.0 4.1 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EGE09004.1 - 1.3e-25 90.3 11.3 1.6e-23 83.4 3.0 3.4 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EGE09004.1 - 0.0019 17.7 0.6 0.0019 17.7 0.6 2.2 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family DUF3663 PF12404.8 EGE09004.1 - 0.18 11.9 0.0 0.57 10.3 0.0 1.8 1 0 0 1 1 1 0 Peptidase Transp_cyt_pur PF02133.15 EGE09005.1 - 2.5e-59 201.2 13.4 1.8e-54 185.2 5.7 2.1 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Zip PF02535.22 EGE09006.1 - 4.1e-38 131.4 25.9 1.4e-30 106.7 18.8 3.5 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.32 EGE09007.1 - 1.1e-36 124.2 21.6 1.1e-06 29.2 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGE09007.1 - 1.8e-10 40.6 0.6 3.4e-10 39.6 0.6 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGE09007.1 - 1.8e-10 41.0 0.8 0.13 12.6 0.0 6.2 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE09007.1 - 6.1e-07 28.5 4.7 0.068 11.8 0.1 5.3 2 2 3 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EGE09007.1 - 4.9e-06 26.1 0.0 0.0026 17.1 0.0 3.2 1 1 2 4 4 4 1 WD40-like domain F-box PF00646.33 EGE09007.1 - 0.00069 19.4 0.6 0.0016 18.2 0.6 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EGE09007.1 - 0.0071 16.0 1.2 0.027 14.0 0.5 2.2 1 1 1 2 2 2 1 PQQ-like domain F-box_5 PF18511.1 EGE09007.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box Sugar_tr PF00083.24 EGE09010.1 - 4.3e-77 259.9 23.8 7.2e-77 259.2 23.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE09010.1 - 6.6e-12 45.0 37.0 3.4e-06 26.2 11.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 EGE09010.1 - 7.9 6.3 12.5 1.2 8.9 0.0 3.5 3 1 0 3 3 3 0 VIT family Fungal_trans PF04082.18 EGE09011.1 - 1.3e-07 30.9 0.2 1.3e-07 30.9 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF5327 PF17261.2 EGE09011.1 - 0.59 10.9 5.7 1.5 9.6 5.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) PAT1 PF09770.9 EGE09011.1 - 8.2 4.6 12.8 11 4.1 12.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RINGv PF12906.7 EGE09013.1 - 1.8e-09 37.5 2.4 1.5e-08 34.6 0.6 2.4 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 EGE09013.1 - 0.13 12.4 1.6 0.82 9.8 0.6 2.4 2 0 0 2 2 2 0 PHD-finger DUF1218 PF06749.12 EGE09013.1 - 0.29 11.7 0.3 0.29 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) zf-RING_2 PF13639.6 EGE09013.1 - 0.39 11.1 3.7 5.5 7.4 0.8 2.3 2 0 0 2 2 2 0 Ring finger domain PHD PF00628.29 EGE09013.1 - 1.8 8.5 6.2 0.5 10.3 2.8 1.8 2 0 0 2 2 2 0 PHD-finger Proteasome PF00227.26 EGE09014.1 - 7.7e-58 195.1 0.0 6.2e-33 113.9 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EGE09014.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.26 EGE09015.1 - 1.1e-40 138.4 0.0 9.5e-20 71.2 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EGE09015.1 - 1.6e-23 82.6 0.0 4e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EGE09015.1 - 7.1e-21 74.7 0.2 7.3e-12 45.6 0.0 3.7 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.29 EGE09015.1 - 1.3e-15 57.6 0.0 2.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE09015.1 - 1.9e-14 53.9 0.0 6.1e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE09015.1 - 3.7e-10 40.1 0.0 1.6e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 EGE09015.1 - 0.012 16.3 0.1 0.11 13.3 0.0 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif zf-C2H2_jaz PF12171.8 EGE09018.1 - 0.0019 18.4 1.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 EGE09018.1 - 0.021 14.7 0.7 3.8 7.5 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EGE09018.1 - 0.073 13.6 3.0 0.83 10.2 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE09018.1 - 0.27 12.2 6.4 13 7.0 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE09018.1 - 3.3 8.3 7.3 1.8 9.1 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double domain 6PGD PF00393.19 EGE09019.1 - 1.2e-75 254.6 0.0 1.7e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGE09019.1 - 1.5e-31 109.7 0.2 2.7e-31 108.9 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGE09019.1 - 7.9e-07 29.1 0.1 1.5e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGE09019.1 - 0.00038 20.5 0.1 0.00069 19.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 EGE09019.1 - 0.0019 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EGE09019.1 - 0.0038 16.8 0.3 0.019 14.6 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EGE09019.1 - 0.0062 17.1 0.1 0.02 15.5 0.1 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGE09019.1 - 0.033 13.5 1.0 0.044 13.1 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EGE09019.1 - 0.035 14.3 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EGE09019.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RTA1 PF04479.13 EGE09020.1 - 5e-72 241.9 5.7 6.6e-72 241.4 5.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3098 PF11297.8 EGE09020.1 - 0.072 12.7 3.0 1.5 8.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Zn_clus PF00172.18 EGE09021.1 - 2.5e-08 33.9 10.6 4.1e-08 33.2 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EGE09021.1 - 6.1e-05 22.0 0.0 9.8e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EB PF01683.18 EGE09022.1 - 0.00047 20.4 4.4 0.00051 20.3 4.4 1.1 1 0 0 1 1 1 1 EB module LSM PF01423.22 EGE09023.1 - 8.5e-15 54.2 0.1 1.5e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.12 EGE09024.1 - 8.8e-79 263.9 0.9 6.4e-76 254.6 0.1 3.2 3 0 0 3 3 3 2 NUC173 domain RsbRD_N PF14361.6 EGE09024.1 - 0.025 15.3 0.1 0.82 10.4 0.0 3.7 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain CPSF100_C PF13299.6 EGE09024.1 - 0.33 11.1 4.5 0.46 10.6 1.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SYF2 PF08231.12 EGE09024.1 - 0.74 10.2 7.7 1.7 9.0 7.7 1.6 1 0 0 1 1 1 0 SYF2 splicing factor CENP-B_dimeris PF09026.10 EGE09025.1 - 0.0005 20.4 21.4 0.00056 20.3 7.3 2.7 2 0 0 2 2 2 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EGE09025.1 - 0.0058 17.0 10.1 0.0058 17.0 10.1 3.3 4 0 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 EGE09025.1 - 0.041 12.6 3.5 0.097 11.4 0.1 2.2 2 0 0 2 2 2 0 Presenilin GEMIN8 PF15348.6 EGE09025.1 - 0.15 12.4 20.3 0.11 12.8 11.3 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 FAM60A PF15396.6 EGE09025.1 - 0.2 11.6 7.2 0.18 11.8 2.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF4834 PF16118.5 EGE09025.1 - 0.84 10.6 5.5 1.2e+02 3.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NOA36 PF06524.12 EGE09025.1 - 0.93 8.8 25.8 0.36 10.1 15.0 2.3 2 0 0 2 2 2 0 NOA36 protein Afi1 PF07792.12 EGE09025.1 - 4.5 7.8 18.6 2.1 8.8 11.3 2.9 2 1 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM76 PF16046.5 EGE09025.1 - 4.8 6.4 9.8 1.7 7.9 0.2 2.1 2 0 0 2 2 2 0 FAM76 protein Radial_spoke PF04712.12 EGE09025.1 - 9.9 5.0 8.7 15 4.4 8.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2615 PF11027.8 EGE09026.1 - 0.00052 20.1 0.4 0.00066 19.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) FAM176 PF14851.6 EGE09026.1 - 0.013 15.1 0.2 0.015 14.9 0.2 1.1 1 0 0 1 1 1 0 FAM176 family Conotoxin PF02950.17 EGE09026.1 - 0.048 14.7 1.3 0.063 14.3 1.3 1.1 1 0 0 1 1 1 0 Conotoxin FixH PF05751.11 EGE09026.1 - 0.054 13.5 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 FixH EphA2_TM PF14575.6 EGE09026.1 - 0.18 12.7 0.1 0.29 12.0 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain GRP PF07172.11 EGE09026.1 - 0.32 11.7 0.1 0.32 11.7 0.1 1.8 2 0 0 2 2 2 0 Glycine rich protein family TPR_1 PF00515.28 EGE09027.1 - 2.5e-49 163.2 31.2 7.9e-08 31.8 0.1 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGE09027.1 - 6.6e-45 147.6 22.5 9.2e-06 25.4 0.0 11.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGE09027.1 - 1.4e-36 121.6 18.8 7e-07 29.0 0.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGE09027.1 - 2.5e-21 74.5 32.0 0.00014 22.0 0.2 10.3 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGE09027.1 - 3.6e-20 72.3 32.4 1.9e-05 25.2 0.0 7.1 7 1 0 8 8 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGE09027.1 - 1.2e-19 69.7 29.1 6.1e-05 22.6 1.5 9.0 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 EGE09027.1 - 7.6e-18 64.8 35.2 2.5e-05 24.7 0.5 7.6 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGE09027.1 - 7.3e-17 60.8 32.0 0.0039 17.7 0.0 10.8 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGE09027.1 - 2.3e-16 59.1 38.9 7.1e-05 23.3 0.1 10.9 5 2 8 13 13 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGE09027.1 - 3.8e-15 54.7 19.4 0.042 13.9 0.1 9.2 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EGE09027.1 - 4.7e-15 55.5 14.5 0.0013 18.9 0.3 7.1 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGE09027.1 - 2e-13 50.4 43.5 0.0002 21.6 0.8 8.6 5 2 4 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE09027.1 - 7.9e-10 38.8 7.5 7.6e-08 32.5 2.0 3.7 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGE09027.1 - 9e-06 25.1 26.5 0.037 13.2 0.1 6.2 2 1 3 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.9 EGE09027.1 - 0.0016 18.2 4.3 0.94 9.2 0.0 2.9 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) ChAPs PF09295.10 EGE09027.1 - 0.35 9.8 2.3 3.2 6.7 0.4 2.6 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EGE09027.1 - 0.89 9.5 16.9 21 5.2 0.2 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 EGE09028.1 - 0.049 14.2 3.2 0.057 14.0 3.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein U3_snoRNA_assoc PF08297.11 EGE09030.1 - 0.055 14.2 11.4 0.069 13.9 11.4 1.2 1 0 0 1 1 1 0 U3 snoRNA associated DUF3807 PF12720.7 EGE09030.1 - 0.48 10.7 10.1 0.52 10.6 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Atrophin-1 PF03154.15 EGE09030.1 - 6.5 4.9 6.6 6.3 4.9 6.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family Ribosomal_L3 PF00297.22 EGE09031.1 - 5.9e-173 575.0 10.3 7.4e-173 574.7 10.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 EGE09032.1 - 0.00026 21.4 0.0 0.00086 19.7 0.0 1.8 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein SR-25 PF10500.9 EGE09032.1 - 0.7 9.5 9.5 0.42 10.2 7.1 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EGE09032.1 - 5.3 7.8 10.2 0.42 11.3 4.7 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein SKN1 PF03935.15 EGE09033.1 - 7.7e-194 644.7 5.0 9.1e-194 644.5 5.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1129 PF06570.11 EGE09034.1 - 1.7 8.1 12.7 0.08 12.4 6.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) PCNA_C PF02747.15 EGE09035.1 - 5.6e-52 175.3 0.0 2.8e-51 173.0 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EGE09035.1 - 8e-33 112.9 0.6 1.6e-32 111.8 0.6 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EGE09035.1 - 0.00034 19.8 0.1 0.00055 19.1 0.1 1.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGE09035.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Rad9 Vezatin PF12632.7 EGE09036.1 - 6e-71 239.1 0.3 6e-71 239.1 0.3 1.8 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes MatE PF01554.18 EGE09036.1 - 0.0027 17.4 0.2 1.5 8.5 0.2 2.2 1 1 1 2 2 2 2 MatE TetR_C_9 PF14514.6 EGE09036.1 - 0.039 14.1 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2157 PF09925.9 EGE09036.1 - 0.044 13.6 1.6 0.086 12.6 1.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) ALMS_motif PF15309.6 EGE09036.1 - 0.12 12.9 3.2 3.8 8.0 1.1 2.6 2 0 0 2 2 2 0 ALMS motif Polysacc_synt_C PF14667.6 EGE09036.1 - 0.14 12.3 5.8 0.21 11.6 5.8 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Ank_2 PF12796.7 EGE09037.1 - 2.5e-44 149.8 3.1 4.6e-09 36.7 0.3 5.5 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE09037.1 - 2.3e-27 95.0 1.6 0.00011 22.7 0.1 7.6 6 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE09037.1 - 1.7e-23 80.1 0.7 0.021 15.3 0.0 10.2 10 1 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 EGE09037.1 - 5.7e-23 80.7 8.6 4.7e-07 30.0 0.4 7.1 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EGE09037.1 - 2.5e-17 62.5 6.5 0.035 14.6 0.2 8.9 9 0 0 9 9 9 4 Ankyrin repeat F-box-like PF12937.7 EGE09037.1 - 0.0013 18.6 0.1 0.0028 17.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE09037.1 - 0.086 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 F-box domain Pedibin PF08182.11 EGE09038.1 - 0.084 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family CH PF00307.31 EGE09039.1 - 9.8e-08 32.2 0.0 0.001 19.3 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.27 EGE09039.1 - 0.0097 15.6 1.4 0.03 14.1 1.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif K-cyclin_vir_C PF09080.10 EGE09041.1 - 0.11 13.0 2.1 9.7 6.7 0.1 2.2 2 0 0 2 2 2 0 K cyclin, C terminal DUF2457 PF10446.9 EGE09042.1 - 3.8e-149 497.8 38.5 3.8e-149 497.8 38.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2457) RPOL_N PF14700.6 EGE09042.1 - 0.87 8.9 7.2 0.083 12.3 2.5 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal CDC45 PF02724.14 EGE09042.1 - 1.8 6.8 35.8 1.8 6.7 27.1 2.3 2 0 0 2 2 2 0 CDC45-like protein APH PF01636.23 EGE09045.1 - 2.2e-14 54.0 0.7 3.7e-14 53.2 0.7 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE09045.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EGE09047.1 - 2.3e-12 46.9 0.0 3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09047.1 - 3e-06 26.7 0.0 4.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE09047.1 - 0.0007 19.0 0.2 0.065 12.5 0.1 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGE09047.1 - 0.00085 19.3 0.2 0.0011 19.0 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE09047.1 - 0.0012 18.2 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGE09047.1 - 0.042 12.6 1.1 0.07 11.9 1.2 1.3 1 1 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 EGE09047.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 EGE09049.1 - 6.6e-09 35.5 0.0 1e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09049.1 - 0.0061 15.9 0.0 0.009 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 EGE09050.1 - 3.4e-19 68.9 1.2 4.2e-08 33.3 0.0 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGE09050.1 - 9.3e-14 50.8 7.0 0.00016 21.4 0.2 5.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE09050.1 - 2e-06 27.5 2.1 0.05 13.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE09050.1 - 1.1e-05 24.9 0.3 1.6e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 EGE09050.1 - 2.6e-05 23.9 3.6 1.9 8.7 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGE09050.1 - 0.00016 21.4 5.3 0.37 10.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGE09050.1 - 0.00021 21.3 2.3 1.7 9.0 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE09050.1 - 0.00033 21.2 0.1 4.2 8.1 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE09050.1 - 0.00061 20.2 6.6 0.084 13.4 1.6 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EGE09050.1 - 0.0019 18.7 0.0 2.6 8.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGE09050.1 - 0.0026 17.5 1.0 0.007 16.1 1.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain OSK PF17182.4 EGE09050.1 - 0.026 13.7 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 OSK domain DUF188 PF02639.14 EGE09050.1 - 0.045 13.4 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 TPR_14 PF13428.6 EGE09050.1 - 0.047 14.5 1.4 1.6e+02 3.5 0.0 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGE09050.1 - 0.1 13.0 3.7 5.2 7.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EGE09050.1 - 0.32 11.3 3.0 31 5.1 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Peptidase_C4 PF00863.19 EGE09056.1 - 0.09 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C4 Kinesin PF00225.23 EGE09059.1 - 6.2e-36 124.0 0.0 1.3e-35 123.0 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.15 EGE09059.1 - 0.00014 21.9 0.5 0.00054 20.0 0.5 2.1 1 0 0 1 1 1 1 Basic region leucine zipper AAA_13 PF13166.6 EGE09059.1 - 0.0069 15.1 3.5 0.0091 14.7 3.5 1.1 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.6 EGE09060.1 - 0.03 15.1 4.4 5.2 8.2 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EGE09061.1 - 7.3e-153 509.2 0.0 1e-152 508.8 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 EGE09061.1 - 0.0004 20.3 0.1 0.95 9.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGE09061.1 - 0.00055 19.6 0.2 7.9 6.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGE09061.1 - 0.00059 20.4 1.7 0.67 10.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE09061.1 - 0.0036 17.8 0.0 6.4 7.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE09061.1 - 0.0048 17.0 0.1 0.67 10.1 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE09061.1 - 0.052 13.9 0.6 1 9.7 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGE09061.1 - 0.61 10.3 3.2 1.5 9.1 0.3 2.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NOA36 PF06524.12 EGE09061.1 - 2.1 7.6 6.6 4 6.7 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EGE09061.1 - 2.3 6.6 4.5 3.6 6.0 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Exo5 PF09810.9 EGE09063.1 - 1.8e-127 425.9 0.0 2.5e-127 425.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EGE09063.1 - 0.0036 17.2 0.3 1.5 8.6 0.0 3.2 4 0 0 4 4 4 2 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 EGE09063.1 - 0.17 11.6 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 PDDEXK-like domain of unknown function (DUF3799) Mpv17_PMP22 PF04117.12 EGE09064.1 - 1.6e-13 50.7 0.3 1.6e-13 50.7 0.3 2.0 2 1 0 2 2 2 1 Mpv17 / PMP22 family Oxidored_q4 PF00507.19 EGE09064.1 - 0.07 13.3 0.0 0.07 13.3 0.0 1.9 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Histone PF00125.24 EGE09065.1 - 2.5e-49 167.0 3.3 2.8e-49 166.8 3.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGE09065.1 - 5.3e-06 26.7 0.0 8.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EGE09065.1 - 6e-05 23.1 0.7 8.5e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EGE09065.1 - 0.0013 19.4 1.2 0.0015 19.1 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EGE09065.1 - 0.0077 16.5 0.2 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGE09065.1 - 0.025 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EGE09065.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EGE09067.1 - 1.1e-08 35.1 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGE09067.1 - 3.7e-05 24.1 0.1 4.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGE09067.1 - 0.00012 22.2 0.1 0.00017 21.7 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGE09067.1 - 0.00049 20.4 0.1 0.00066 20.0 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGE09067.1 - 0.00053 20.2 0.1 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGE09067.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGE09067.1 - 0.052 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated HIGH_NTase1_ass PF16581.5 EGE09067.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sperm_Ag_HE2 PF05324.13 EGE09069.1 - 0.031 14.7 1.1 12 6.4 0.2 3.2 3 0 0 3 3 3 0 Sperm antigen HE2 UPF0767 PF15990.5 EGE09069.1 - 0.13 12.4 0.3 0.21 11.7 0.3 1.3 1 0 0 1 1 1 0 UPF0767 family zf-C2H2 PF00096.26 EGE09070.1 - 0.00012 22.3 33.0 0.00015 22.0 1.4 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGE09070.1 - 0.028 15.2 1.1 0.028 15.2 1.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE09070.1 - 0.29 11.6 10.3 13 6.4 0.0 4.0 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_transf_22 PF03901.17 EGE09071.1 - 9.2e-87 292.0 15.9 1.1e-86 291.7 15.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3128 PF11326.8 EGE09072.1 - 0.025 14.9 0.1 0.025 14.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Gar1 PF04410.14 EGE09073.1 - 4.7e-10 39.5 0.2 1.1e-09 38.2 0.2 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Troponin-I_N PF11636.8 EGE09074.1 - 0.32 11.0 2.9 0.37 10.8 1.1 2.0 2 0 0 2 2 2 0 Troponin I residues 1-32 RRM_1 PF00076.22 EGE09075.1 - 2.4e-05 24.1 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_28 PF02636.17 EGE09076.1 - 1.4e-82 277.3 0.0 2.1e-82 276.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.20 EGE09077.1 - 2.5e-09 37.6 0.0 3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.20 EGE09078.1 - 1.2e-07 31.3 1.3 1.7e-07 30.9 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 SH3-WW_linker PF16618.5 EGE09079.1 - 0.069 13.6 0.4 0.11 12.9 0.4 1.3 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 PGI PF00342.19 EGE09080.1 - 1.8e-207 689.8 1.3 2.2e-207 689.5 1.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Urease_beta PF00699.20 EGE09080.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Urease beta subunit PUD1_2 PF18457.1 EGE09082.1 - 2.4e-42 144.9 0.6 2.8e-42 144.7 0.6 1.0 1 0 0 1 1 1 1 Up-Regulated in long-lived daf-2 PWI PF01480.17 EGE09083.1 - 6.1e-17 61.7 0.7 1.5e-16 60.4 0.7 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EGE09083.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.19 EGE09084.1 - 5.5e-26 91.4 0.0 9.5e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MR_MLE_C PF13378.6 EGE09085.1 - 2.1e-56 190.9 0.0 3.2e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EGE09085.1 - 2.8e-07 30.8 0.1 5.5e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EGE09085.1 - 0.0055 15.9 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus TIM21 PF08294.11 EGE09086.1 - 4e-39 133.8 0.0 5.1e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EGE09086.1 - 2.8e-06 27.1 0.0 6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 EGE09087.1 - 9.8e-35 119.2 0.4 1.7e-34 118.4 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.22 EGE09088.1 - 1.4e-80 270.5 0.2 1.8e-80 270.1 0.2 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EGE09088.1 - 3.3e-35 121.0 0.0 7.1e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EGE09090.1 - 1.6e-50 172.4 2.2 5.1e-50 170.7 1.8 1.7 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 EGE09090.1 - 8.1e-11 41.5 1.4 1.5e-09 37.4 0.7 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGE09090.1 - 1.4e-07 30.9 2.3 2.3e-07 30.2 2.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EGE09090.1 - 0.0026 17.0 0.2 0.0043 16.3 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EGE09090.1 - 0.005 16.0 1.3 0.0087 15.2 1.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase eIF3g PF12353.8 EGE09091.1 - 5.6e-45 152.8 1.6 5.6e-45 152.8 1.6 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EGE09091.1 - 2.2e-17 62.6 0.2 3.6e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGE09091.1 - 0.0065 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_7 PF18586.1 EGE09091.1 - 0.0095 16.2 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 TackOD1 PF18551.1 EGE09091.1 - 0.049 13.3 0.1 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 NDT80_PhoG PF05224.12 EGE09093.1 - 4.5e-38 131.3 0.1 6.7e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_18 PF00704.28 EGE09094.1 - 2.2e-40 139.3 0.0 2.9e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EGE09094.1 - 7.3e-13 48.3 0.1 1.4e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 LysM domain DEC-1_N PF04625.13 EGE09094.1 - 0.76 8.7 3.9 0.94 8.4 3.9 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FMO-like PF00743.19 EGE09095.1 - 2.7e-18 65.7 0.1 3.6e-17 62.0 0.1 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGE09095.1 - 1e-12 48.0 0.0 7.5e-12 45.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE09095.1 - 1.7e-09 37.8 0.0 3.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGE09095.1 - 6.8e-08 32.0 0.1 6.3e-06 25.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGE09095.1 - 1.2e-07 31.3 0.0 1.7e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGE09095.1 - 3.6e-05 23.5 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGE09095.1 - 0.00059 19.9 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EGE09095.1 - 0.0098 15.2 0.2 0.017 14.3 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGE09095.1 - 0.024 13.7 0.3 0.034 13.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGE09095.1 - 0.03 14.3 0.0 0.16 12.0 0.0 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding MrpF_PhaF PF04066.13 EGE09095.1 - 0.035 14.5 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) FAD_oxidored PF12831.7 EGE09095.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGE09095.1 - 0.46 9.1 1.4 0.8 8.3 1.4 1.3 1 0 0 1 1 1 0 HI0933-like protein MIF4G PF02854.19 EGE09096.1 - 7.8e-57 192.3 0.0 1.2e-30 106.7 0.0 3.8 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 EGE09096.1 - 1.8e-40 138.8 13.3 1.8e-40 138.8 13.3 2.8 3 0 0 3 3 3 1 Up-frameshift suppressor 2 TraF PF13728.6 EGE09096.1 - 3.6 7.3 13.6 5 6.9 2.2 3.6 3 0 0 3 3 3 0 F plasmid transfer operon protein TPK_catalytic PF04263.16 EGE09098.1 - 4.3e-30 104.2 0.0 7.4e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGE09098.1 - 3e-18 65.3 0.1 4.9e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 EGE09099.1 - 0.00043 20.3 0.7 0.00069 19.7 0.7 1.4 1 0 0 1 1 1 1 CHCH domain Mito_carr PF00153.27 EGE09101.1 - 5.3e-62 205.8 4.5 2e-20 72.5 1.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein UPF0121 PF03661.13 EGE09102.1 - 1.5e-17 63.8 2.2 5.1e-11 42.4 0.1 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) Claudin_2 PF13903.6 EGE09102.1 - 1.9 8.2 8.2 1 9.1 2.3 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Septin PF00735.18 EGE09104.1 - 5.3e-119 396.6 0.1 5.3e-119 396.6 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGE09104.1 - 6.6e-07 29.4 0.2 2.5e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE09104.1 - 5.9e-05 23.0 0.2 5.9e-05 23.0 0.2 3.4 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EGE09104.1 - 0.00041 19.9 1.5 0.058 12.9 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGE09104.1 - 0.0005 20.6 3.6 0.082 13.4 0.0 2.9 2 1 1 3 3 3 1 ABC transporter AAA_16 PF13191.6 EGE09104.1 - 0.0021 18.5 0.2 0.0073 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGE09104.1 - 0.0038 17.5 0.5 0.023 14.9 0.0 2.5 2 2 1 3 3 3 1 AAA domain AAA_23 PF13476.6 EGE09104.1 - 0.0065 17.0 7.7 2.6 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ras PF00071.22 EGE09104.1 - 0.022 14.4 0.0 0.085 12.5 0.0 2.0 1 1 0 1 1 1 0 Ras family AAA_29 PF13555.6 EGE09104.1 - 0.032 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EGE09104.1 - 0.036 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Exonuc_VII_L PF02601.15 EGE09104.1 - 0.089 12.3 7.3 0.16 11.5 7.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 EGE09104.1 - 0.32 10.7 5.0 1.3 8.8 0.0 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EGE09104.1 - 0.93 9.5 7.5 14 5.7 0.0 3.7 3 1 0 3 3 3 0 Dynamin family DUF2937 PF11157.8 EGE09104.1 - 1.2 8.8 8.6 0.14 11.8 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Strep_SA_rep PF06696.11 EGE09104.1 - 3.7 7.7 5.6 3.5 7.7 3.7 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 EGE09104.1 - 4 7.5 5.6 22 5.0 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 EGE09104.1 - 5.4 6.0 9.0 8.1 5.4 9.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NAD_binding_8 PF13450.6 EGE09106.1 - 1.8e-14 53.7 0.0 9.2e-14 51.4 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EGE09106.1 - 0.0024 17.2 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGE09106.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGE09106.1 - 0.023 13.6 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EGE09106.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EGE09106.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE09106.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RFC1 PF08519.12 EGE09107.1 - 1.4e-58 197.5 0.2 9.4e-58 194.8 0.1 2.3 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EGE09107.1 - 2.1e-13 50.4 0.0 6.6e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EGE09107.1 - 2.3e-09 37.7 1.3 3.5e-09 37.2 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGE09107.1 - 0.00021 21.3 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGE09107.1 - 0.00073 19.8 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGE09107.1 - 0.0029 17.4 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE09107.1 - 0.003 18.0 0.1 0.012 16.0 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGE09107.1 - 0.0072 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE09107.1 - 0.0076 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGE09107.1 - 0.014 15.9 0.0 0.047 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGE09107.1 - 0.038 13.7 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EGE09107.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGE09107.1 - 0.064 13.2 0.1 0.4 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EGE09107.1 - 0.096 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Ribosomal_L16 PF00252.18 EGE09108.1 - 9.6e-31 106.5 0.1 1.4e-30 106.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 EGE09109.1 - 1e-10 41.6 0.1 2e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGE09109.1 - 8.5e-07 29.5 0.1 1.6e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGE09109.1 - 4.2e-06 27.1 0.1 1.5e-05 25.2 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGE09109.1 - 0.00056 20.3 0.3 0.0046 17.4 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EGE09109.1 - 0.0012 18.6 0.4 0.0031 17.3 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 EGE09109.1 - 0.006 17.0 0.1 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGE09109.1 - 0.0071 16.3 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 EGE09109.1 - 0.021 15.3 0.1 0.044 14.3 0.1 1.7 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 EGE09109.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.15 EGE09109.1 - 0.11 12.5 0.2 0.61 10.1 0.2 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TK PF00265.18 EGE09109.1 - 0.19 11.6 0.7 0.91 9.4 0.7 1.9 1 1 0 1 1 1 0 Thymidine kinase CtaG_Cox11 PF04442.14 EGE09110.1 - 5.8e-57 191.9 0.0 7.9e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF1444 PF07285.11 EGE09111.1 - 0.056 13.0 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) DUF2371 PF10177.9 EGE09111.1 - 0.072 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Polysacc_deac_1 PF01522.21 EGE09112.1 - 7.5e-28 96.9 0.0 1.3e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EGE09112.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Peptidase_M35 PF02102.15 EGE09115.1 - 6e-106 354.3 4.7 7.1e-106 354.1 4.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EGE09115.1 - 9.7e-43 146.2 0.6 1.8e-42 145.3 0.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EGE09115.1 - 0.00047 19.8 0.5 0.003 17.2 0.5 1.9 1 1 0 1 1 1 1 Putative peptidase family Semialdhyde_dhC PF02774.18 EGE09116.1 - 2.3e-37 128.9 0.0 3.3e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EGE09116.1 - 1.3e-29 103.1 0.0 5e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EGE09116.1 - 0.0021 18.9 0.0 0.0041 17.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 EGE09116.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TMEM135_C_rich PF15982.5 EGE09117.1 - 0.00091 19.8 1.8 0.0021 18.7 1.8 1.6 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 EGE09117.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.5 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus HLH PF00010.26 EGE09118.1 - 1.6e-06 27.9 0.1 4.9e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4778 PF16008.5 EGE09118.1 - 0.12 12.4 5.1 0.33 11.0 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Sporozoite_P67 PF05642.11 EGE09118.1 - 2.7 6.0 9.7 4.2 5.3 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SprA-related PF12118.8 EGE09118.1 - 6.6 5.8 15.3 5.3 6.1 2.5 2.2 2 0 0 2 2 2 0 SprA-related family BTRD1 PF17660.1 EGE09119.1 - 4.7e-75 247.2 12.5 4.4e-16 58.4 0.3 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 Ser_hydrolase PF06821.13 EGE09119.1 - 0.0035 17.2 0.0 0.0066 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase UvrA_inter PF17760.1 EGE09119.1 - 0.043 13.9 0.1 1.7 8.7 0.0 3.0 2 1 1 3 3 3 0 UvrA interaction domain DUF4342 PF14242.6 EGE09119.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DUF3884 PF13024.6 EGE09119.1 - 0.21 11.1 1.8 8.8 6.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) APH PF01636.23 EGE09120.1 - 1e-17 64.8 0.0 2.2e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGE09120.1 - 0.00034 20.0 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EGE09120.1 - 0.00043 19.3 0.1 0.062 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 EGE09120.1 - 0.21 10.9 0.0 4 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain CENP-Q PF13094.6 EGE09121.1 - 2.1e-41 141.9 7.5 3.3e-41 141.3 7.5 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit BRE1 PF08647.11 EGE09121.1 - 0.01 15.9 10.3 0.029 14.4 10.3 1.8 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Leu_zip PF15294.6 EGE09121.1 - 0.01 15.4 5.6 0.01 15.4 5.6 1.5 2 0 0 2 2 2 0 Leucine zipper ZapB PF06005.12 EGE09121.1 - 0.012 16.1 12.1 0.012 16.1 12.1 2.6 3 1 0 3 3 3 0 Cell division protein ZapB DUF4407 PF14362.6 EGE09121.1 - 0.33 10.3 6.2 0.41 9.9 5.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) STATa_Ig PF18214.1 EGE09121.1 - 0.34 10.9 1.4 0.44 10.6 0.3 1.8 2 1 1 3 3 3 0 STATa Immunoglobulin-like domain DUF4337 PF14235.6 EGE09121.1 - 1 9.5 4.5 2 8.5 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1840 PF08895.11 EGE09121.1 - 1.9 8.8 6.2 6.2 7.2 6.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Atg14 PF10186.9 EGE09121.1 - 2.4 7.2 6.6 0.76 8.8 3.7 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 EGE09121.1 - 2.9 8.1 16.6 20 5.4 0.1 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.8 EGE09121.1 - 5 7.4 12.6 0.56 10.4 7.3 2.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.11 EGE09121.1 - 9.4 6.5 8.4 16 5.8 7.2 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 SPO22 PF08631.10 EGE09123.1 - 7.9e-18 64.9 4.5 8.2e-18 64.9 1.7 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like WD40 PF00400.32 EGE09124.1 - 3.3e-21 75.2 8.5 0.00074 20.3 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat FTA2 PF13095.6 EGE09125.1 - 3.4e-42 144.5 0.0 6.9e-40 137.0 0.0 2.6 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Sugar_tr PF00083.24 EGE09128.1 - 8.2e-79 265.6 27.5 9.4e-79 265.4 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE09128.1 - 1.9e-21 76.4 30.4 3.4e-20 72.3 28.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily PIG-Y PF15159.6 EGE09128.1 - 5.6 8.0 11.2 0.15 13.0 1.9 3.3 3 1 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y GCN5L1 PF06320.13 EGE09129.1 - 3.5e-17 62.6 1.6 5.7e-17 61.9 1.6 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.8 EGE09129.1 - 0.018 14.5 2.3 0.019 14.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DASH_Dad2 PF08654.10 EGE09129.1 - 0.032 14.6 0.6 0.14 12.6 0.5 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad2 Cellsynth_D PF03500.13 EGE09129.1 - 0.14 12.1 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Cellulose synthase subunit D DivIC PF04977.15 EGE09129.1 - 0.3 10.9 2.3 0.56 10.0 2.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Syntaxin-6_N PF09177.11 EGE09129.1 - 2 9.0 5.9 92 3.7 5.9 2.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DNA_mis_repair PF01119.19 EGE09130.1 - 7.9e-21 73.9 0.0 2.9e-19 68.9 0.0 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EGE09130.1 - 1.8e-19 69.9 2.1 3.6e-16 59.2 1.1 3.1 3 0 0 3 3 3 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGE09130.1 - 0.12 12.2 0.0 0.57 10.0 0.0 2.2 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DASH_Spc19 PF08287.11 EGE09130.1 - 4.2 7.2 7.4 0.84 9.5 0.5 2.7 1 1 1 3 3 3 0 Spc19 Serinc PF03348.15 EGE09131.1 - 4.4e-92 309.2 2.7 8.3e-91 305.1 2.7 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) TcpE PF12648.7 EGE09131.1 - 0.026 15.1 0.2 0.17 12.4 0.0 2.4 3 0 0 3 3 3 0 TcpE family DUF21 PF01595.20 EGE09131.1 - 0.087 12.5 1.6 0.45 10.2 0.1 2.3 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Spem1 PF15670.5 EGE09131.1 - 0.72 9.4 3.3 3.2 7.2 1.4 2.2 1 1 1 2 2 2 0 Spermatid maturation protein 1 Nodulin-like PF06813.13 EGE09132.1 - 9.2e-21 74.5 6.1 1.4e-20 73.9 6.1 1.2 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EGE09132.1 - 2.6e-14 52.9 8.3 2.6e-14 52.9 8.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGE09132.1 - 0.11 10.9 1.5 0.14 10.5 1.5 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.24 EGE09132.1 - 0.11 11.3 11.2 0.39 9.5 11.7 1.6 1 1 1 2 2 2 0 Sugar (and other) transporter AAA_2 PF07724.14 EGE09133.1 - 3.2e-38 131.5 0.0 4.1e-37 127.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGE09133.1 - 1.2e-14 54.9 0.0 2.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGE09133.1 - 2.8e-09 36.9 0.3 9.1e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGE09133.1 - 1.7e-06 28.1 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGE09133.1 - 0.00017 21.0 0.1 0.0077 15.6 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGE09133.1 - 0.00033 20.4 0.0 0.096 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EGE09133.1 - 0.0026 16.9 0.4 0.0066 15.6 0.1 1.8 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EGE09133.1 - 0.0029 18.0 0.1 0.012 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGE09133.1 - 0.0039 17.5 0.3 0.033 14.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGE09133.1 - 0.0041 16.9 0.0 0.0073 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGE09133.1 - 0.0049 16.6 0.2 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGE09133.1 - 0.005 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGE09133.1 - 0.042 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGE09133.1 - 0.051 14.1 0.2 0.22 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGE09133.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EGE09133.1 - 0.068 13.7 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EGE09133.1 - 0.074 13.2 0.6 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGE09133.1 - 0.088 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGE09133.1 - 0.094 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGE09133.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Chromo PF00385.24 EGE09134.1 - 1.9e-08 34.1 0.1 5.8e-08 32.5 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGE09134.1 - 0.0081 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Ras PF00071.22 EGE09135.1 - 3.9e-63 211.9 0.2 4.6e-63 211.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE09135.1 - 3e-35 121.1 0.2 4.2e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE09135.1 - 2e-13 50.1 0.1 2.6e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGE09135.1 - 1.2e-07 31.7 0.1 2e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGE09135.1 - 0.00016 21.6 1.3 0.017 15.0 0.2 2.2 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGE09135.1 - 0.00021 20.9 0.1 0.00091 18.8 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGE09135.1 - 0.00055 19.4 0.1 0.00088 18.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGE09135.1 - 0.0017 18.7 0.1 0.013 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGE09135.1 - 0.0077 15.7 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EGE09135.1 - 0.014 15.4 0.1 0.048 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGE09135.1 - 0.014 15.7 0.1 0.026 14.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGE09135.1 - 0.017 15.6 0.1 0.025 15.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EGE09135.1 - 0.024 14.4 0.1 0.061 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGE09135.1 - 0.035 13.5 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 EGE09135.1 - 0.038 14.1 0.1 0.81 9.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MCM PF00493.23 EGE09135.1 - 0.091 11.8 0.0 0.22 10.6 0.0 1.7 1 1 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 EGE09135.1 - 0.097 12.5 0.9 0.13 12.0 0.9 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EGE09135.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 EGE09135.1 - 0.11 12.0 0.1 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B F-box-like PF12937.7 EGE09136.1 - 1.1e-07 31.7 0.3 8.5e-07 28.8 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGE09136.1 - 0.0022 17.9 0.1 0.008 16.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain Brix PF04427.18 EGE09137.1 - 6e-32 111.3 0.0 8.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Elongin_A PF06881.11 EGE09137.1 - 0.022 15.3 0.0 0.053 14.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BUD22 PF09073.10 EGE09137.1 - 0.045 13.1 12.6 0.014 14.7 7.8 2.0 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EGE09137.1 - 0.12 10.6 9.4 0.21 9.8 9.4 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGE09137.1 - 0.24 9.6 5.2 0.43 8.8 5.2 1.4 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGE09137.1 - 1.2 7.6 5.0 1.7 7.1 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TEX19 PF15553.6 EGE09137.1 - 1.6 8.6 3.1 3.6 7.5 3.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 TRAP_alpha PF03896.16 EGE09137.1 - 3 7.0 7.1 5.6 6.1 7.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 EGE09137.1 - 8.5 4.3 20.7 12 3.8 20.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi WW PF00397.26 EGE09138.1 - 3.3e-10 39.9 2.5 7.4e-10 38.8 2.5 1.7 1 0 0 1 1 1 1 WW domain DUF3623 PF12291.8 EGE09140.1 - 0.012 14.8 1.8 0.02 14.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) Abp2 PF09441.10 EGE09141.1 - 4.1e-86 287.3 0.1 8e-86 286.4 0.1 1.4 1 0 0 1 1 1 1 ARS binding protein 2 ORC6 PF05460.13 EGE09142.1 - 0.052 12.8 4.8 0.069 12.4 4.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM171 PF15471.6 EGE09144.1 - 1 8.3 7.2 1.3 7.9 7.2 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Glycophorin_A PF01102.18 EGE09147.1 - 0.0036 17.5 0.5 0.011 15.9 0.5 1.8 1 1 0 1 1 1 1 Glycophorin A Mucin PF01456.17 EGE09147.1 - 0.013 15.5 12.8 0.02 14.9 12.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3246 PF11596.8 EGE09149.1 - 0.077 12.4 4.8 0.1 12.0 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) ORC6 PF05460.13 EGE09149.1 - 4.3 6.5 10.9 9 5.5 11.3 1.4 1 1 1 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF829 PF05705.14 EGE09150.1 - 3.5e-48 164.6 0.0 4.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ODR4-like PF14778.6 EGE09150.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like UFD1 PF03152.14 EGE09151.1 - 1.6e-75 252.3 0.0 2.2e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EGE09151.1 - 0.05 13.4 0.0 0.81 9.5 0.0 2.2 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.16 EGE09152.1 - 4.6e-08 32.6 1.0 1.1e-07 31.4 1.0 1.7 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.13 EGE09153.1 - 4.9e-153 509.4 1.4 4.9e-153 509.4 1.4 1.4 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EGE09153.1 - 7.7e-21 74.0 0.5 3.2e-20 72.0 0.1 2.3 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA PF00004.29 EGE09153.1 - 6.7e-08 33.0 0.1 9e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGE09153.1 - 2e-07 30.9 0.5 0.0002 21.1 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE09153.1 - 2.2e-05 24.9 0.1 6.2e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EGE09153.1 - 5e-05 22.8 0.6 9e-05 21.9 0.6 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EGE09153.1 - 0.0021 17.5 0.8 0.027 13.9 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGE09153.1 - 0.0083 16.1 0.1 0.62 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGE09153.1 - 0.015 15.6 0.0 0.99 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGE09153.1 - 0.026 14.2 0.0 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGE09153.1 - 0.051 13.9 1.6 1.8 8.9 1.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGE09153.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGE09153.1 - 0.062 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EGE09153.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EGE09153.1 - 0.12 11.9 0.2 0.49 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region HSBP1 PF06825.12 EGE09154.1 - 3e-06 27.0 2.9 0.096 12.6 0.0 5.4 5 0 0 5 5 4 1 Heat shock factor binding protein 1 GAS PF13851.6 EGE09154.1 - 0.00029 20.3 0.4 0.00029 20.3 0.4 5.1 3 1 2 5 5 5 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EGE09154.1 - 0.00052 20.0 21.9 0.14 12.2 0.6 5.2 4 3 0 4 4 4 1 Protein of unknown function (DUF1664) Cortex-I_coil PF09304.10 EGE09154.1 - 0.011 16.0 34.3 0.043 14.0 1.2 6.5 3 2 3 7 7 7 0 Cortexillin I, coiled coil Baculo_PEP_C PF04513.12 EGE09154.1 - 0.014 15.5 33.1 0.48 10.5 1.6 5.7 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus HrpB7 PF09486.10 EGE09154.1 - 0.014 15.7 3.4 0.014 15.7 3.4 4.2 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.11 EGE09154.1 - 0.081 13.3 22.6 1 9.8 0.4 7.0 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EGE09154.1 - 0.18 12.1 24.8 3.8 7.8 0.5 7.1 3 1 5 8 8 8 0 Bacterial protein of unknown function (DUF948) Flavodoxin_3 PF12641.7 EGE09154.1 - 0.19 11.4 1.9 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Flavodoxin domain MtrB PF05440.12 EGE09154.1 - 0.2 12.1 2.6 40 4.7 0.0 4.6 4 2 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B KxDL PF10241.9 EGE09154.1 - 0.24 11.7 0.1 0.24 11.7 0.1 6.6 5 2 2 7 7 6 0 Uncharacterized conserved protein PRD PF00874.20 EGE09154.1 - 0.29 11.5 2.6 30 5.0 0.2 3.4 2 1 0 2 2 2 0 PRD domain CENP-F_leu_zip PF10473.9 EGE09154.1 - 0.36 10.8 34.1 0.54 10.3 0.8 5.2 2 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YvrJ PF12841.7 EGE09154.1 - 0.45 10.1 3.2 91 2.7 0.0 4.5 4 0 0 4 4 4 0 YvrJ protein family DUF4407 PF14362.6 EGE09154.1 - 0.72 9.2 34.8 2.6 7.3 12.0 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EGE09154.1 - 0.73 9.9 19.9 2.9 8.0 0.5 5.5 3 2 2 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.9 EGE09154.1 - 0.91 9.9 27.1 0.095 13.0 1.2 7.1 4 2 3 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EGE09154.1 - 1.3 8.0 36.5 5.5 6.0 0.3 3.9 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 EGE09154.1 - 1.4 7.0 35.8 1.6 6.8 23.6 3.8 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Snapin_Pallidin PF14712.6 EGE09154.1 - 1.8 9.0 27.9 0.71 10.3 4.0 6.1 5 1 1 6 6 6 0 Snapin/Pallidin Phasin PF05597.11 EGE09154.1 - 2.1 8.4 24.8 0.82 9.7 1.8 5.3 4 1 1 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GAIN_A PF18619.1 EGE09154.1 - 2.5 8.4 5.9 8.7 6.6 0.9 3.5 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF3782 PF12644.7 EGE09154.1 - 2.6 8.3 7.6 12 6.2 0.0 4.7 5 0 0 5 5 4 0 Protein of unknown function (DUF3782) DUF3584 PF12128.8 EGE09154.1 - 5.1 4.5 41.6 0.52 7.7 19.4 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EGE09154.1 - 7.8 6.3 32.4 0.58 10.0 5.0 4.8 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) HIP1_clath_bdg PF16515.5 EGE09154.1 - 8.6 7.0 36.0 0.08 13.6 7.7 5.4 4 2 3 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FSH1 PF03959.13 EGE09155.1 - 5.4e-29 101.4 0.0 7.3e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EGE09155.1 - 0.029 14.2 0.4 1.1 9.0 0.2 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_25 PF13649.6 EGE09156.1 - 5.7e-14 52.6 0.0 1.2e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE09156.1 - 7.9e-10 39.3 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE09156.1 - 1.5e-08 34.7 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE09156.1 - 3e-08 33.6 0.0 4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE09156.1 - 5.8e-08 33.4 0.0 1.3e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGE09156.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 EGE09156.1 - 0.0059 16.0 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_20 PF12147.8 EGE09156.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 EGE09156.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase MTS PF05175.14 EGE09156.1 - 0.026 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 EGE09156.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Peptidase_M14 PF00246.24 EGE09157.1 - 6.9e-81 272.2 0.0 5.8e-80 269.2 0.0 1.9 2 0 0 2 2 2 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EGE09157.1 - 8.6e-11 42.1 0.7 1.8e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide SMI1_KNR4 PF09346.10 EGE09159.1 - 1e-33 116.6 0.0 1.9e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) PNRC PF15365.6 EGE09160.1 - 1e-08 34.8 7.7 1e-08 34.8 7.7 4.6 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 EGE09161.1 - 5.5e-25 87.4 12.5 7.7e-25 86.9 12.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGE09161.1 - 3.5e-17 62.2 10.0 4.6e-17 61.9 10.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGE09161.1 - 2.4e-06 27.8 14.7 8e-05 22.9 14.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE09161.1 - 5e-05 23.1 3.3 5e-05 23.1 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE09161.1 - 0.0026 17.6 11.7 0.045 13.6 11.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGE09161.1 - 0.11 12.6 8.9 0.56 10.4 9.0 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EGE09161.1 - 0.42 10.5 10.8 0.83 9.6 4.4 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE09161.1 - 0.61 10.2 8.2 2.2 8.4 8.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGE09161.1 - 0.69 9.6 14.3 1e+02 2.6 14.3 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGE09161.1 - 1.1 9.0 17.1 1e+02 2.8 17.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger SPC12 PF06645.13 EGE09162.1 - 4.5e-26 90.7 1.4 5.6e-26 90.4 1.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 EGE09164.1 - 3.5e-30 105.1 36.3 3.5e-30 105.1 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE09164.1 - 8.2e-15 54.6 8.6 1.3e-14 53.9 8.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter YqcI_YcgG PF08892.11 EGE09165.1 - 6.3e-66 222.2 0.1 8.2e-66 221.8 0.1 1.2 1 0 0 1 1 1 1 YqcI/YcgG family CorA PF01544.18 EGE09166.1 - 4.1e-43 147.8 0.0 5.4e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mid1 PF12929.7 EGE09167.1 - 2.8e-154 514.4 3.4 3.3e-154 514.2 3.4 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EGE09167.1 - 0.00025 21.6 7.2 0.014 16.0 3.0 2.5 2 0 0 2 2 2 2 Fz domain Es2 PF09751.9 EGE09168.1 - 1.6e-140 469.7 17.1 2e-140 469.4 17.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Zn_clus PF00172.18 EGE09172.1 - 1.8e-06 28.0 10.3 3e-06 27.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 EGE09173.1 - 4.2e-06 27.4 0.1 6.4e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE09173.1 - 0.068 13.4 0.0 0.39 10.9 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Phage_Mu_Gam PF07352.12 EGE09173.1 - 0.11 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Ribosomal_S8 PF00410.19 EGE09174.1 - 3.1e-09 36.9 0.1 5.3e-09 36.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 ubiquitin PF00240.23 EGE09176.1 - 5.2e-06 26.1 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EGE09176.1 - 0.00035 21.1 0.1 0.00097 19.7 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.15 EGE09177.1 - 1.8e-75 252.9 0.0 6.6e-75 251.0 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.20 EGE09178.1 - 1.7e-37 128.7 14.9 7.3e-31 107.1 0.1 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGE09178.1 - 7.8e-26 90.9 7.2 7.8e-26 90.9 7.2 2.9 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EGE09178.1 - 8.1e-17 60.7 0.0 1.7e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGE09178.1 - 1.4e-15 57.2 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGE09178.1 - 3.8e-07 30.6 0.0 1.4e-05 25.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGE09178.1 - 0.003 17.4 1.0 0.005 16.6 1.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EGE09178.1 - 0.0032 17.4 0.6 0.0073 16.2 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Wzy_C PF04932.15 EGE09178.1 - 0.26 10.9 3.8 0.3 10.7 0.0 2.7 3 0 0 3 3 3 0 O-Antigen ligase ANAPC10 PF03256.16 EGE09179.1 - 6.7e-36 123.7 0.0 3.1e-35 121.5 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) BUD22 PF09073.10 EGE09179.1 - 0.24 10.7 24.3 0.061 12.7 11.7 2.1 2 0 0 2 2 2 0 BUD22 DNA_pol_phi PF04931.13 EGE09179.1 - 1.8 6.6 37.6 0.22 9.6 22.7 2.0 2 0 0 2 2 2 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EGE09179.1 - 2.5 7.8 30.1 0.59 9.8 5.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 EGE09179.1 - 5.9 7.6 27.4 2.6 8.8 5.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Iso_dh PF00180.20 EGE09180.1 - 6.4e-128 426.8 0.0 7.2e-128 426.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_lid_3 PF17862.1 EGE09180.1 - 0.043 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain Methyltransf_23 PF13489.6 EGE09182.1 - 2.1e-20 73.2 0.0 3.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGE09182.1 - 7.6e-10 39.4 0.0 2e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE09182.1 - 8.2e-09 35.4 0.0 6.6e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE09182.1 - 3.3e-07 30.9 0.0 9.8e-07 29.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE09182.1 - 8.8e-06 26.4 0.0 6.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGE09182.1 - 0.0018 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGE09182.1 - 0.0083 16.3 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Sterol_MT_C PF08498.10 EGE09182.1 - 0.013 15.8 0.1 0.059 13.7 0.1 2.2 2 1 0 2 2 1 0 Sterol methyltransferase C-terminal Methyltransf_16 PF10294.9 EGE09182.1 - 0.034 13.9 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 EGE09182.1 - 0.036 13.5 0.0 0.089 12.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 EGE09182.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CDP-OH_P_transf PF01066.21 EGE09183.1 - 1.8e-12 47.8 0.3 1.8e-12 47.8 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 EGE09184.1 - 9.9e-32 110.6 0.0 9.1e-26 91.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGE09184.1 - 0.0052 16.4 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Rap1a PF18602.1 EGE09185.1 - 0.11 12.9 0.8 0.22 11.8 0.8 1.5 1 0 0 1 1 1 0 Rap1a immunity proteins DUF5423 PF17461.2 EGE09185.1 - 0.64 8.8 10.5 0.89 8.3 10.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) ATG16 PF08614.11 EGE09186.1 - 0.015 15.5 1.9 0.026 14.8 1.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GrpE PF01025.19 EGE09186.1 - 0.41 10.3 4.3 4.5 6.9 2.0 2.8 2 1 1 3 3 3 0 GrpE ABC_tran_CTD PF16326.5 EGE09186.1 - 1.4 9.2 6.3 44 4.4 6.7 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 EGE09186.1 - 2.3 8.2 5.9 5.2 7.0 1.1 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Serglycin PF04360.12 EGE09186.1 - 8.7 6.3 12.8 0.084 12.8 2.6 2.4 2 0 0 2 2 2 0 Serglycin RRM_1 PF00076.22 EGE09187.1 - 1e-40 137.4 0.4 1.5e-18 66.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGE09187.1 - 2.1e-26 92.8 0.4 5e-24 85.2 0.2 3.0 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EGE09187.1 - 0.00069 19.4 0.0 0.96 9.4 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EGE09187.1 - 0.056 13.5 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 EGE09187.1 - 0.059 13.5 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EGE09187.1 - 0.061 13.5 0.1 5.1 7.3 0.1 2.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter MFS_1 PF07690.16 EGE09188.1 - 1.5e-36 126.1 42.5 2.1e-35 122.3 41.4 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE09188.1 - 4.4e-11 42.3 12.1 4.4e-11 42.3 12.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Ac76 PF05814.11 EGE09188.1 - 0.0019 18.1 1.1 0.5 10.4 0.2 2.6 2 0 0 2 2 2 2 Orf76 (Ac76) OATP PF03137.20 EGE09188.1 - 0.0067 14.8 2.1 0.0067 14.8 2.1 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF2721 PF11026.8 EGE09188.1 - 0.025 14.5 0.2 0.025 14.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) DUF2561 PF10812.8 EGE09188.1 - 0.036 14.1 4.9 0.04 14.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Cyt-b5 PF00173.28 EGE09190.1 - 2.1e-18 66.2 0.1 2.1e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGE09190.1 - 1.5e-12 48.0 15.6 1.5e-12 48.0 15.6 1.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EGE09190.1 - 0.0069 16.6 0.4 0.014 15.6 0.4 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Nsp3_PL2pro PF12124.8 EGE09191.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain OMPdecase PF00215.24 EGE09192.1 - 1.6e-08 34.5 0.0 1.3e-06 28.2 0.0 2.4 2 1 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cu-oxidase_2 PF07731.14 EGE09193.1 - 2.6e-49 166.5 8.4 8.1e-43 145.4 0.4 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 EGE09193.1 - 6.7e-42 142.3 2.0 1.2e-38 131.7 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EGE09193.1 - 1.6e-37 129.1 1.2 3.8e-33 114.9 0.3 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EGE09193.1 - 0.00066 19.8 0.0 4.2 7.5 0.0 3.5 2 1 0 2 2 2 2 Cupredoxin-like domain FTR1 PF03239.14 EGE09195.1 - 1e-72 244.9 7.2 1.3e-72 244.6 7.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 EGE09195.1 - 0.019 13.7 0.7 0.03 13.1 0.7 1.3 1 0 0 1 1 1 0 Rft protein DUF4231 PF14015.6 EGE09195.1 - 0.025 15.0 0.5 0.025 15.0 0.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) FtsX PF02687.21 EGE09195.1 - 0.055 13.9 1.0 0.055 13.9 1.0 3.0 2 1 0 2 2 2 0 FtsX-like permease family Herpes_glycop PF01528.16 EGE09195.1 - 0.48 9.2 3.5 0.74 8.6 0.4 2.2 1 1 1 2 2 2 0 Herpesvirus glycoprotein M Trep_Strep PF09605.10 EGE09195.1 - 5 7.1 15.4 2.7 7.9 7.5 3.0 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Adap_comp_sub PF00928.21 EGE09197.1 - 1.9e-12 47.2 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGE09197.1 - 3.6e-08 33.4 0.1 6.1e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EGE09197.1 - 0.0017 18.7 0.2 0.0034 17.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 EGE09198.1 - 3.3e-18 65.7 0.0 5.6e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 EGE09201.1 - 7.8e-105 350.2 15.0 9.1e-105 350.0 15.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EGE09201.1 - 1.2e-06 28.8 31.7 4e-05 23.8 8.0 3.3 3 0 0 3 3 3 3 EamA-like transporter family Acyl_transf_3 PF01757.22 EGE09201.1 - 0.0026 16.9 7.2 0.0026 16.9 7.2 2.2 1 1 1 2 2 2 2 Acyltransferase family Syja_N PF02383.18 EGE09202.1 - 6.9e-43 147.2 0.0 1.2e-42 146.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EGE09202.1 - 6.3e-39 132.3 0.0 1.1e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase HEAT_EZ PF13513.6 EGE09203.1 - 3.5e-30 104.0 12.6 1.4e-15 57.4 0.0 10.1 7 3 4 11 11 11 5 HEAT-like repeat HEAT PF02985.22 EGE09203.1 - 1.9e-22 77.4 18.3 7.5e-05 22.7 0.0 11.6 14 0 0 14 14 13 3 HEAT repeat HEAT_2 PF13646.6 EGE09203.1 - 4.8e-18 65.3 2.2 1.8e-05 25.0 0.0 8.1 5 3 3 8 8 8 3 HEAT repeats Cnd1 PF12717.7 EGE09203.1 - 1.3e-11 44.8 0.0 0.0042 17.1 0.0 5.9 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EGE09203.1 - 1.6e-08 34.1 5.9 0.42 9.7 0.3 5.4 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EGE09203.1 - 5.2e-08 33.4 0.0 0.074 13.6 0.0 4.5 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGE09203.1 - 8.7e-08 32.0 0.4 0.0045 16.6 0.2 5.7 3 3 2 5 5 5 1 CLASP N terminal Xpo1 PF08389.12 EGE09203.1 - 2e-05 24.7 0.1 0.00048 20.2 0.0 3.4 4 1 0 4 4 1 1 Exportin 1-like protein RIX1 PF08167.12 EGE09203.1 - 5.1e-05 23.1 0.8 3.1 7.5 0.0 5.5 5 1 1 6 6 6 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EGE09203.1 - 7.8e-05 22.5 0.8 0.012 15.5 0.0 4.2 3 2 1 4 4 4 1 Importin-beta N-terminal domain Sec7_N PF12783.7 EGE09203.1 - 0.00031 20.7 0.3 0.0099 15.8 0.1 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.20 EGE09203.1 - 0.00047 18.8 0.1 0.16 10.5 0.0 3.8 2 2 1 3 3 3 1 Adaptin N terminal region DUF3437 PF11919.8 EGE09203.1 - 0.00062 19.6 0.7 0.16 11.9 0.0 4.6 6 0 0 6 6 5 1 Domain of unknown function (DUF3437) Dopey_N PF04118.14 EGE09203.1 - 0.00077 18.7 0.0 0.06 12.4 0.0 2.5 2 0 0 2 2 2 1 Dopey, N-terminal Arm PF00514.23 EGE09203.1 - 0.0027 17.7 6.7 2.1 8.5 0.0 6.1 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGE09203.1 - 0.0045 17.1 0.0 0.03 14.5 0.0 2.5 2 0 0 2 2 1 1 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 EGE09203.1 - 0.085 12.6 0.0 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 DNA alkylation repair enzyme HEAT_PBS PF03130.16 EGE09203.1 - 0.19 12.5 4.5 27 5.8 0.0 5.3 7 0 0 7 7 3 0 PBS lyase HEAT-like repeat TAFH PF07531.14 EGE09203.1 - 0.93 9.6 7.0 29 4.8 0.0 5.3 6 0 0 6 6 5 0 NHR1 homology to TAF DUF2846 PF11008.8 EGE09204.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) PPI_Ypi1 PF07491.11 EGE09205.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF3719 PF12516.8 EGE09205.1 - 0.023 14.4 0.2 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) LRR19-TM PF15176.6 EGE09205.1 - 0.12 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Rb_C PF08934.10 EGE09206.1 - 4.2 7.2 4.9 2.1 8.2 1.4 2.1 2 1 1 3 3 3 0 Rb C-terminal domain Peptidase_C12 PF01088.21 EGE09207.1 - 3.7e-68 229.4 0.0 5.4e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGE09207.1 - 6.6e-08 32.3 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases GP120 PF00516.18 EGE09208.1 - 0.11 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Redoxin PF08534.10 EGE09211.1 - 1.2e-30 106.2 0.0 1.4e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGE09211.1 - 3.4e-07 30.2 0.0 4.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family BolA PF01722.18 EGE09212.1 - 6.5e-19 68.0 0.0 1.8e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 EGE09213.1 - 1.4e-56 191.8 0.0 2.2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COG6 PF06419.11 EGE09214.1 - 8.3e-207 688.3 0.5 9.4e-207 688.1 0.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Transcrip_act PF04949.13 EGE09214.1 - 0.0032 17.4 0.3 0.013 15.4 0.3 2.2 1 0 0 1 1 1 1 Transcriptional activator HSP9_HSP12 PF04119.12 EGE09215.1 - 2.6e-26 91.8 3.7 2.6e-26 91.8 3.7 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Chlorosome_CsmC PF11098.8 EGE09215.1 - 0.019 14.9 0.2 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Chlorosome envelope protein C NYN PF01936.18 EGE09216.1 - 0.0002 21.9 0.1 0.0027 18.2 0.1 2.3 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.12 EGE09217.1 - 6.1e-31 107.6 0.0 8.7e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF2576 PF10845.8 EGE09217.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) SprT-like PF10263.9 EGE09218.1 - 3.5e-36 123.5 0.6 6.4e-36 122.6 0.2 1.6 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 EGE09218.1 - 2.9e-07 30.3 6.2 7.6e-07 28.9 6.2 1.8 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EGE09218.1 - 0.99 9.6 4.7 2.8 8.1 2.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Glyco_hydro_72 PF03198.14 EGE09219.1 - 2.1e-109 365.6 12.1 1.2e-59 202.1 0.5 2.1 1 1 1 2 2 2 2 Glucanosyltransferase X8 PF07983.13 EGE09219.1 - 2e-26 92.5 3.9 5.6e-26 91.0 3.9 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EGE09219.1 - 3.6e-05 23.0 2.1 0.00015 21.0 1.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 EGE09219.1 - 0.006 16.1 0.5 3 7.2 0.2 2.2 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.15 EGE09222.1 - 0 1370.9 0.0 0 1370.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EGE09222.1 - 5.4e-22 78.5 0.0 1.2e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 ATPgrasp_N PF18130.1 EGE09223.1 - 1e-16 61.3 0.0 3.2e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EGE09223.1 - 1.2e-08 34.7 0.0 6e-08 32.4 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGE09223.1 - 2.3e-08 33.8 0.0 2.2e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGE09223.1 - 0.0016 18.6 0.0 0.04 14.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGE09223.1 - 0.01 15.3 0.0 0.035 13.6 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain AP_endonuc_2 PF01261.24 EGE09223.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel GARS_A PF01071.19 EGE09223.1 - 0.033 14.0 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Aminotran_1_2 PF00155.21 EGE09225.1 - 5e-34 118.1 0.0 6.3e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGE09225.1 - 0.04 12.5 0.0 0.34 9.4 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.18 EGE09226.1 - 1.3e-05 25.0 4.0 1.7e-05 24.6 0.4 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 DUF2013 PF09431.10 EGE09227.1 - 7.1e-51 172.0 1.8 7.1e-51 172.0 1.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) ABC_membrane PF00664.23 EGE09228.1 - 4e-42 144.8 12.9 5.1e-42 144.4 12.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGE09228.1 - 5.3e-34 117.7 0.0 1.1e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGE09228.1 - 1.1e-05 25.1 0.0 0.0016 17.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGE09228.1 - 0.00013 22.2 0.0 0.00047 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE09228.1 - 0.00019 21.9 0.0 0.00044 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EGE09228.1 - 0.00072 19.5 0.1 0.011 15.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGE09228.1 - 0.011 15.8 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGE09228.1 - 0.015 15.0 0.1 0.039 13.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EGE09228.1 - 0.019 14.7 0.5 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGE09228.1 - 0.019 15.5 0.0 0.058 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGE09228.1 - 0.023 14.7 0.1 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGE09228.1 - 0.028 14.3 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EGE09228.1 - 0.035 14.7 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGE09228.1 - 0.035 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGE09228.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rop-like PF05082.13 EGE09228.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Rop-like AAA PF00004.29 EGE09228.1 - 0.059 13.8 0.0 0.45 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGE09228.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain GPAT_N PF14829.6 EGE09228.1 - 0.066 13.2 0.0 8.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ATP-synt_ab PF00006.25 EGE09228.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 EGE09228.1 - 0.067 13.4 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain G-alpha PF00503.20 EGE09228.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 EGE09228.1 - 0.13 11.5 0.3 0.84 8.9 0.0 2.5 4 0 0 4 4 4 0 Zeta toxin IstB_IS21 PF01695.17 EGE09228.1 - 0.36 10.5 2.2 13 5.5 0.0 3.0 4 0 0 4 4 3 0 IstB-like ATP binding protein AIM24 PF01987.17 EGE09229.1 - 1.3e-50 172.0 0.2 1.6e-50 171.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Peptidase_M43 PF05572.13 EGE09231.1 - 2.1e-15 57.0 0.6 4.7e-15 55.8 0.6 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EGE09231.1 - 0.00045 20.4 2.4 0.00085 19.5 2.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EGE09231.1 - 0.0052 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EGE09231.1 - 0.0082 16.3 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_3 PF13582.6 EGE09231.1 - 0.0094 16.5 0.5 0.025 15.1 0.5 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EGE09231.1 - 0.0095 15.8 0.8 0.014 15.3 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EGE09231.1 - 0.072 12.9 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin HRI1 PF16815.5 EGE09232.1 - 2.3e-26 93.0 0.1 3.8e-26 92.2 0.1 1.4 1 1 0 1 1 1 1 Protein HRI1 YebF PF13995.6 EGE09232.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 YebF-like protein Chromate_transp PF02417.15 EGE09233.1 - 8.1e-63 211.3 36.0 1.2e-32 113.2 14.8 2.3 2 0 0 2 2 2 2 Chromate transporter Ndc1_Nup PF09531.10 EGE09233.1 - 4.6 5.8 4.8 13 4.3 4.4 1.8 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_1 PF00170.21 EGE09234.1 - 0.033 14.3 4.7 0.074 13.2 4.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor NICE-3 PF07406.11 EGE09234.1 - 0.06 13.3 1.1 0.13 12.3 1.1 1.5 1 0 0 1 1 1 0 NICE-3 protein TSC22 PF01166.18 EGE09234.1 - 0.29 11.5 4.3 6.2 7.2 0.1 2.9 1 1 2 3 3 3 0 TSC-22/dip/bun family TRAF_BIRC3_bd PF16673.5 EGE09234.1 - 1.5 8.7 5.8 0.68 9.8 2.6 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Med9 PF07544.13 EGE09234.1 - 3.4 7.8 7.4 3.2 7.9 1.7 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MFS_1 PF07690.16 EGE09235.1 - 2.3e-24 86.0 46.8 6.4e-17 61.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 EGE09236.1 - 8.2e-81 271.5 0.2 1.2e-80 271.0 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGE09236.1 - 1.6e-17 63.8 0.0 3.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 EGE09236.1 - 0.0079 16.0 0.1 2.6 8.1 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif TPR_14 PF13428.6 EGE09236.1 - 0.17 12.8 0.3 0.79 10.7 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 EGE09237.1 - 8.5e-72 241.6 0.0 1.8e-71 240.5 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGE09237.1 - 5.4e-22 77.6 0.0 1.9e-21 75.8 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGE09237.1 - 8.5e-17 61.7 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGE09237.1 - 1.2e-15 57.3 3.9 2.2e-15 56.4 3.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGE09237.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGE09237.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 EGE09238.1 - 3.1e-57 193.9 0.1 6.1e-53 179.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09238.1 - 4.4e-28 98.3 0.0 5.8e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGE09238.1 - 0.00036 19.9 0.2 0.00057 19.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGE09238.1 - 0.002 17.1 0.1 0.0033 16.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGE09238.1 - 0.0047 16.3 0.0 0.0098 15.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGE09238.1 - 0.02 14.8 0.2 0.046 13.6 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGE09238.1 - 0.06 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 S_100 PF01023.19 EGE09238.1 - 0.29 10.9 2.2 0.36 10.6 0.8 1.8 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain HEM4 PF02602.15 EGE09239.1 - 1.5e-37 129.2 0.0 3.5e-37 128.0 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 EGE09240.1 - 9.3e-20 71.1 0.0 2.3e-18 66.5 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09240.1 - 1.5e-12 47.4 0.0 3.3e-10 39.7 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Nt_Gln_amidase PF09764.9 EGE09240.1 - 0.093 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 N-terminal glutamine amidase Epimerase PF01370.21 EGE09243.1 - 1.8e-14 53.8 0.1 5.9e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGE09243.1 - 5.3e-12 46.0 0.0 9.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE09243.1 - 1.8e-11 44.1 0.0 2.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EGE09243.1 - 2.1e-11 43.3 0.1 3.7e-11 42.5 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGE09243.1 - 2.5e-07 30.4 0.3 6.5e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGE09243.1 - 0.00011 21.5 0.1 0.014 14.5 0.0 2.8 1 1 1 3 3 3 1 Male sterility protein adh_short PF00106.25 EGE09243.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGE09243.1 - 0.00058 19.0 0.0 0.052 12.6 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 EGE09243.1 - 0.004 16.8 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HIM1 PF08732.10 EGE09243.1 - 0.024 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 HIM1 DDE_Tnp_1_3 PF13612.6 EGE09243.1 - 0.11 12.5 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain KR PF08659.10 EGE09243.1 - 0.14 12.0 0.0 2 8.3 0.0 2.3 3 0 0 3 3 3 0 KR domain Steroid_dh PF02544.16 EGE09245.1 - 0.56 10.2 2.9 7.8 6.5 1.5 2.3 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA-synt_1d PF00750.19 EGE09247.1 - 8.6e-96 320.9 8.7 3.4e-94 315.6 8.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGE09247.1 - 8.8e-29 100.1 0.0 2.2e-28 98.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGE09247.1 - 1.1e-05 26.0 0.8 5.1e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF16 PF01519.16 EGE09247.1 - 0.059 13.9 4.3 0.38 11.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 WD40 PF00400.32 EGE09248.1 - 1.3e-10 41.6 18.3 9.8e-05 23.1 0.3 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE09248.1 - 8.8e-05 22.7 0.3 2.7 8.3 0.0 4.8 4 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE09248.1 - 0.1 11.5 0.7 0.4 9.6 0.1 2.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_6 PF00970.24 EGE09249.1 - 4.8e-32 110.2 0.0 8e-32 109.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGE09249.1 - 3.9e-28 98.3 0.0 6.2e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGE09249.1 - 1.8e-05 24.9 0.0 0.0018 18.4 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4176 PF13780.6 EGE09249.1 - 0.017 15.2 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) FAD_binding_9 PF08021.11 EGE09249.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3605 PF12239.8 EGE09250.1 - 8.3e-61 204.8 0.3 9.8e-61 204.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Dfp1_Him1_M PF08630.10 EGE09250.1 - 0.11 12.7 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Dfp1/Him1, central region SMC_N PF02463.19 EGE09251.1 - 2.6e-69 233.0 12.1 6.5e-69 231.7 12.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGE09251.1 - 3.8e-32 111.0 0.3 6.5e-31 107.1 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGE09251.1 - 3.1e-18 67.0 4.5 3.1e-18 67.0 4.5 6.2 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EGE09251.1 - 2.1e-17 63.9 4.1 2.3e-09 37.5 0.2 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGE09251.1 - 1.6e-14 54.4 19.4 2e-10 41.0 9.5 4.1 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EGE09251.1 - 0.0052 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 EGE09251.1 - 0.014 16.0 125.0 0.028 14.9 11.5 7.4 5 3 2 7 7 7 0 Apg6 coiled-coil region SbcCD_C PF13558.6 EGE09251.1 - 0.026 14.7 0.3 0.15 12.3 0.1 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EGE09251.1 - 0.45 11.0 0.0 0.45 11.0 0.0 5.9 4 2 0 5 5 5 0 ABC transporter DUF87 PF01935.17 EGE09251.1 - 2.7 8.0 0.0 2.7 8.0 0.0 6.4 3 2 2 5 5 5 0 Helicase HerA, central domain RIO1 PF01163.22 EGE09252.1 - 2.1e-72 242.7 0.1 2.1e-72 242.7 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGE09252.1 - 2.5e-05 24.3 0.2 0.0062 16.5 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGE09252.1 - 0.0027 17.1 0.6 0.031 13.6 0.6 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGE09252.1 - 0.084 12.5 0.8 0.19 11.3 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF3464 PF11947.8 EGE09252.1 - 0.18 11.6 2.6 0.55 10.0 2.6 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Kinase-PolyVal PF18762.1 EGE09252.1 - 0.28 11.1 1.6 0.54 10.2 0.1 2.3 3 0 0 3 3 3 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pkinase_fungal PF17667.1 EGE09252.1 - 0.59 8.9 4.5 0.1 11.4 0.4 1.7 2 0 0 2 2 2 0 Fungal protein kinase CENP-Q PF13094.6 EGE09253.1 - 0.041 14.1 0.6 0.082 13.1 0.6 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit THEG4 PF15834.5 EGE09253.1 - 0.12 12.4 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 TrbC PF04956.13 EGE09257.1 - 0.12 12.7 1.5 0.15 12.3 1.5 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family WD40 PF00400.32 EGE09258.1 - 3.1e-46 154.4 22.1 5.7e-09 36.5 0.5 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EGE09258.1 - 3.5e-15 55.6 0.4 7.4e-15 54.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE09258.1 - 1.9e-11 43.5 0.3 5.1e-11 42.2 0.1 1.9 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EGE09258.1 - 1.3e-09 37.3 6.8 0.062 11.9 0.2 5.7 4 2 1 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGE09258.1 - 4.5e-09 36.5 0.3 0.0012 19.1 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EGE09258.1 - 0.0012 18.7 0.1 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EGE09258.1 - 0.0013 18.2 0.2 0.002 17.5 0.2 1.2 1 0 0 1 1 1 1 WD40-like domain APG17 PF04108.12 EGE09259.1 - 4.1e-128 427.9 0.4 4.8e-128 427.6 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Tweety PF04906.13 EGE09259.1 - 0.02 13.6 1.0 0.26 9.9 0.0 2.5 3 0 0 3 3 3 0 Tweety DUF3969 PF13108.6 EGE09259.1 - 1 9.4 3.0 5.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3969) DUF4795 PF16043.5 EGE09259.1 - 2.4 7.7 6.9 0.44 10.1 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) 7TMR-HDED PF07697.11 EGE09259.1 - 2.8 8.0 8.8 18 5.4 8.8 2.6 1 1 0 1 1 1 0 7TM-HD extracellular NAD_binding_10 PF13460.6 EGE09261.1 - 8.3e-11 42.1 0.0 2.6e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGE09261.1 - 0.00016 21.3 0.3 0.0007 19.2 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EGE09261.1 - 0.0028 17.1 0.1 0.0046 16.4 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE09261.1 - 0.026 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Peptidase_M28 PF04389.17 EGE09262.1 - 1.6e-07 31.2 0.4 0.0014 18.4 0.1 2.2 2 0 0 2 2 2 2 Peptidase family M28 fn3 PF00041.21 EGE09262.1 - 0.036 14.4 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain PGAP1 PF07819.13 EGE09263.1 - 1.2e-84 283.6 0.0 1.8e-84 283.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGE09263.1 - 6.6e-05 23.6 0.0 0.00012 22.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGE09263.1 - 0.00057 19.8 0.0 0.00092 19.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EGE09263.1 - 0.0008 19.1 0.3 0.002 17.8 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGE09263.1 - 0.0023 17.6 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGE09263.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EGE09263.1 - 0.0057 15.9 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EGE09263.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glyco_transf_90 PF05686.12 EGE09264.1 - 7.2e-28 97.6 1.2 9.8e-28 97.2 1.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EGE09264.1 - 0.052 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ank_2 PF12796.7 EGE09265.1 - 1e-10 42.0 0.0 8.9e-06 26.2 0.0 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE09265.1 - 2.3e-08 33.6 0.0 1.2 10.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGE09265.1 - 1.7e-07 31.6 0.0 0.031 14.9 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGE09265.1 - 1.9e-07 31.2 0.4 0.13 12.8 0.0 4.8 6 0 0 6 6 6 3 Ankyrin repeat YbaB_DNA_bd PF02575.16 EGE09265.1 - 0.035 14.3 0.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family ResIII PF04851.15 EGE09266.1 - 2.5e-25 89.5 0.0 4.6e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGE09266.1 - 3.9e-11 43.0 0.0 6.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGE09266.1 - 3.8e-08 33.7 0.0 4.3e-07 30.3 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EGE09266.1 - 2.9e-06 27.1 0.0 5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EGE09266.1 - 6.1e-05 22.4 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EGE09266.1 - 0.055 13.0 0.4 1.1 8.8 0.0 2.3 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EGE09266.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pkinase_Tyr PF07714.17 EGE09267.1 - 1.7e-09 37.3 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGE09267.1 - 7.5e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGE09267.1 - 1.8e-07 31.3 0.0 8.3e-06 25.9 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE09267.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGE09267.1 - 0.062 12.9 0.0 0.38 10.3 0.0 1.9 1 1 1 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EGE09267.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EGE09267.1 - 0.091 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGE09267.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2457 PF10446.9 EGE09268.1 - 0.54 9.3 23.8 1.1 8.3 23.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.12 EGE09268.1 - 0.6 9.9 16.7 1.1 9.0 16.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 EGE09268.1 - 1.3 8.3 8.0 2.7 7.2 8.0 1.5 1 0 0 1 1 1 0 NOA36 protein SWIRM PF04433.17 EGE09269.1 - 6.2e-31 106.6 0.0 1.5e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGE09269.1 - 1.9e-30 104.6 8.5 4.9e-30 103.3 8.5 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGE09269.1 - 1.4e-09 37.9 0.1 2.6e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGE09269.1 - 6e-06 26.4 0.2 1.3e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EGE09269.1 - 1.8 8.4 4.5 0.66 9.8 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type DUF3450 PF11932.8 EGE09270.1 - 0.79 9.0 10.4 6.1 6.1 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 EGE09270.1 - 2.4 8.2 11.6 2.3 8.3 0.5 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EGE09270.1 - 2.7 8.2 6.6 0.72 10.0 1.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 EGE09270.1 - 3.2 7.9 8.5 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation Matrilin_ccoil PF10393.9 EGE09270.1 - 4.2 7.3 9.3 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin AAA PF00004.29 EGE09271.1 - 8.9e-12 45.6 0.0 1.7e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGE09271.1 - 2.3e-06 27.7 0.1 9.3e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EGE09271.1 - 4.2e-06 27.1 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGE09271.1 - 6.3e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGE09271.1 - 2e-05 24.4 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGE09271.1 - 0.001 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGE09271.1 - 0.0026 17.9 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGE09271.1 - 0.0028 18.1 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EGE09271.1 - 0.033 14.1 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 EGE09271.1 - 0.039 13.2 0.0 0.084 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF1776 PF08643.10 EGE09271.1 - 0.041 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) AAA_19 PF13245.6 EGE09271.1 - 0.076 13.3 0.4 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGE09271.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGE09271.1 - 0.14 12.1 1.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase DUF3619 PF12279.8 EGE09273.1 - 2.2 8.6 9.9 1.8 8.9 2.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3619) Retinal PF15449.6 EGE09273.1 - 3.6 5.2 9.8 4.4 5.0 9.8 1.0 1 0 0 1 1 1 0 Retinal protein Kdo PF06293.14 EGE09274.1 - 3.2e-07 29.9 0.1 6.2e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGE09274.1 - 9.1e-07 29.0 1.1 2.6e-05 24.2 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGE09274.1 - 5.3e-05 22.7 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EGE09274.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGE09274.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family CarD_CdnL_TRCF PF02559.16 EGE09274.1 - 0.16 12.7 0.1 0.4 11.4 0.1 1.6 1 1 0 1 1 1 0 CarD-like/TRCF domain ETF PF01012.21 EGE09276.1 - 6.8e-41 140.2 2.4 1.3e-40 139.2 2.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGE09276.1 - 2.2e-33 114.1 0.1 5.8e-33 112.8 0.1 1.8 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ribosomal_L1 PF00687.21 EGE09277.1 - 6.1e-57 192.7 0.2 6.1e-57 192.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family RNA_pol_3_Rpc31 PF11705.8 EGE09277.1 - 4.1 7.6 11.3 0.49 10.6 4.7 2.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 APH PF01636.23 EGE09280.1 - 1.5e-16 61.1 0.0 6.1e-16 59.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EGE09280.1 - 0.00023 20.2 0.1 0.17 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GREB1 PF15782.5 EGE09281.1 - 2.5 5.1 8.6 3.2 4.7 8.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp PF00026.23 EGE09282.1 - 4.6e-15 55.9 0.2 6.7e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Phage_holin_2_4 PF16082.5 EGE09282.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like TAXi_N PF14543.6 EGE09282.1 - 0.017 15.3 0.3 0.053 13.7 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Mid2 PF04478.12 EGE09282.1 - 0.091 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EGE09282.1 - 2.6 8.1 6.0 3 7.9 0.4 2.2 2 0 0 2 2 2 0 Podoplanin zf-C3HC4_3 PF13920.6 EGE09283.1 - 1.8e-09 37.3 12.2 3.1e-09 36.6 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGE09283.1 - 0.11 12.4 13.1 0.2 11.6 13.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGE09284.1 - 1.5e-08 34.5 8.1 3.2e-08 33.4 8.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGE09284.1 - 0.00038 20.3 4.2 0.00096 19.0 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGE09284.1 - 0.00041 20.3 1.7 0.00041 20.3 1.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger CCCAP PF15964.5 EGE09284.1 - 0.00041 18.8 3.3 0.00061 18.2 3.3 1.3 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Prok-RING_4 PF14447.6 EGE09284.1 - 0.00049 19.9 5.9 0.00097 18.9 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGE09284.1 - 0.00086 19.6 6.8 0.0021 18.4 6.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGE09284.1 - 0.0012 18.6 4.1 0.0053 16.6 4.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IFT57 PF10498.9 EGE09284.1 - 0.0037 16.3 1.8 0.0047 15.9 1.8 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4472 PF14739.6 EGE09284.1 - 0.004 17.9 4.3 0.0065 17.2 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) ZapB PF06005.12 EGE09284.1 - 0.0094 16.4 4.3 0.016 15.6 4.3 1.4 1 0 0 1 1 1 1 Cell division protein ZapB RmuC PF02646.16 EGE09284.1 - 0.011 14.8 3.7 0.016 14.3 3.7 1.3 1 0 0 1 1 1 0 RmuC family Prefoldin PF02996.17 EGE09284.1 - 0.016 15.1 1.4 0.029 14.3 1.4 1.5 1 0 0 1 1 1 0 Prefoldin subunit DUF4403 PF14356.6 EGE09284.1 - 0.017 13.8 0.2 0.029 13.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) DUF1664 PF07889.12 EGE09284.1 - 0.019 15.0 3.5 0.034 14.2 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Mod_r PF07200.13 EGE09284.1 - 0.027 14.6 6.7 0.042 13.9 6.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zf-C3HC4_4 PF15227.6 EGE09284.1 - 0.041 14.0 5.6 0.043 14.0 4.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGE09284.1 - 0.042 13.7 2.9 0.093 12.6 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Phage_Mu_Gam PF07352.12 EGE09284.1 - 0.055 13.4 2.8 0.09 12.7 2.8 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF87 PF01935.17 EGE09284.1 - 0.089 12.9 1.6 0.13 12.3 1.6 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Exonuc_VII_L PF02601.15 EGE09284.1 - 0.11 12.1 3.3 0.14 11.7 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec23_helical PF04815.15 EGE09284.1 - 0.11 12.3 4.5 0.56 10.1 1.8 2.9 2 1 0 2 2 2 0 Sec23/Sec24 helical domain zf-rbx1 PF12678.7 EGE09284.1 - 0.13 12.5 3.6 0.36 11.1 3.6 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain OmpH PF03938.14 EGE09284.1 - 0.2 12.0 6.3 0.31 11.4 6.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TSC22 PF01166.18 EGE09284.1 - 0.2 12.0 2.8 0.5 10.7 2.5 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family CEP19 PF14933.6 EGE09284.1 - 0.56 10.5 6.7 0.96 9.7 6.7 1.3 1 0 0 1 1 1 0 CEP19-like protein zf-P11 PF03854.14 EGE09284.1 - 0.85 9.3 4.3 2.3 7.9 4.3 1.8 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 EGE09284.1 - 1.1 9.3 6.1 5.5 7.1 6.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon DUF4407 PF14362.6 EGE09284.1 - 1.7 8.0 6.0 2.1 7.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DNA_ligase_ZBD PF03119.16 EGE09284.1 - 2.7 8.1 5.4 25 5.0 0.5 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Ly49 PF08391.10 EGE09284.1 - 3.5 8.0 7.3 7.6 6.9 7.0 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region IBR PF01485.21 EGE09284.1 - 9.9 6.5 8.7 2.7 8.3 2.7 2.6 1 1 0 2 2 2 0 IBR domain, a half RING-finger domain XAP5 PF04921.14 EGE09285.1 - 1.6e-83 280.3 0.0 3.1e-83 279.4 0.0 1.4 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EGE09285.1 - 0.0048 17.3 6.0 0.009 16.5 6.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Fip1 PF05182.13 EGE09286.1 - 3e-20 71.4 1.1 5.3e-20 70.7 1.1 1.4 1 0 0 1 1 1 1 Fip1 motif WRNPLPNID PF15017.6 EGE09286.1 - 1.3 10.0 9.9 4 8.4 9.9 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CPSF100_C PF13299.6 EGE09286.1 - 2 8.6 4.9 3.1 8.0 4.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 EGE09286.1 - 2.4 6.2 10.3 3.1 5.8 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EGE09286.1 - 2.8 6.0 10.7 3.6 5.7 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 EGE09286.1 - 4.4 6.8 7.2 6.1 6.3 7.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cpn10 PF00166.21 EGE09287.1 - 2.7e-27 94.6 0.0 3e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.6 EGE09289.1 - 0.00014 22.6 47.9 0.0065 17.3 26.3 2.5 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF1664 PF07889.12 EGE09289.1 - 0.0044 17.0 0.5 0.96 9.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Lectin_N PF03954.14 EGE09289.1 - 0.17 11.7 0.3 7.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain WD40 PF00400.32 EGE09290.1 - 0.014 16.2 11.5 17 6.5 1.0 6.7 6 2 0 6 6 6 0 WD domain, G-beta repeat Lactonase PF10282.9 EGE09290.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF2841 PF11001.8 EGE09294.1 - 0.14 12.2 0.1 0.76 9.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2841) HAD_2 PF13419.6 EGE09296.1 - 7.2e-07 29.5 0.0 9.1e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGE09296.1 - 0.12 12.7 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Evr1_Alr PF04777.13 EGE09296.1 - 0.18 12.3 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 Erv1 / Alr family Pkinase PF00069.25 EGE09297.1 - 1.3e-34 119.7 0.0 4.6e-34 118.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09297.1 - 1.4e-17 63.8 0.0 9.5e-17 61.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE09297.1 - 0.15 10.8 0.4 0.31 9.8 0.2 1.3 1 1 0 1 1 1 0 Fungal protein kinase TPR_1 PF00515.28 EGE09298.1 - 9.1e-08 31.6 0.6 0.00034 20.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGE09298.1 - 8.4e-05 22.2 0.1 0.00022 20.8 0.1 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EGE09298.1 - 8.6e-05 22.4 3.3 0.03 14.4 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGE09298.1 - 0.00015 22.0 0.5 0.00041 20.6 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE09298.1 - 0.00053 19.8 0.8 0.13 12.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ELH PF02323.15 EGE09298.1 - 0.0012 18.3 0.4 0.0019 17.6 0.1 1.4 2 0 0 2 2 2 1 Egg-laying hormone precursor TPR_14 PF13428.6 EGE09298.1 - 0.0075 17.0 0.4 0.22 12.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGE09298.1 - 0.1 13.1 0.0 0.42 11.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3112 PF11309.8 EGE09300.1 - 9.2e-13 48.1 7.5 4e-10 39.5 0.7 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) Abhydrolase_9_N PF15420.6 EGE09300.1 - 2 8.3 11.9 0.3 11.1 6.0 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus adh_short_C2 PF13561.6 EGE09301.1 - 2.1e-50 171.5 1.0 2.6e-50 171.2 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE09301.1 - 2.8e-46 157.5 0.8 3.6e-46 157.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE09301.1 - 2.5e-11 43.8 0.2 3.5e-11 43.3 0.2 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EGE09301.1 - 0.019 14.3 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGE09301.1 - 0.022 14.1 0.2 0.034 13.5 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EGE09301.1 - 0.023 14.7 0.4 0.04 14.0 0.4 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 EGE09301.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGE09301.1 - 0.073 12.5 0.4 4.2 6.8 0.2 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.27 EGE09301.1 - 0.1 13.2 0.5 0.1 13.2 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 EGE09302.1 - 1.6e-37 130.0 0.4 2.7e-37 129.3 0.4 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGE09302.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PI31_Prot_N PF11566.8 EGE09303.1 - 8.2e-37 126.5 0.0 1.2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGE09303.1 - 2.1e-18 67.3 13.4 2.1e-18 67.3 13.4 2.5 2 0 0 2 2 2 1 PI31 proteasome regulator GPW_gp25 PF04965.14 EGE09304.1 - 0.089 12.6 0.1 0.091 12.5 0.1 1.0 1 0 0 1 1 1 0 Gene 25-like lysozyme DUF2183 PF09949.9 EGE09305.1 - 6.4e-32 109.8 0.0 2.2e-31 108.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) HrpB2 PF09487.10 EGE09305.1 - 0.0026 18.1 0.2 0.0071 16.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB2) CarboxypepD_reg PF13620.6 EGE09305.1 - 0.047 14.0 0.1 0.4 11.0 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RPAP1_N PF08621.10 EGE09305.1 - 0.11 12.3 2.4 0.2 11.4 2.4 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Metallophos PF00149.28 EGE09306.1 - 2e-06 28.5 0.0 3.1e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE09306.1 - 3e-06 27.5 0.0 0.00046 20.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain LEA_6 PF10714.9 EGE09307.1 - 0.4 10.8 3.9 0.98 9.5 0.7 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Roughex PF06020.11 EGE09307.1 - 7.8 5.5 6.1 13 4.7 6.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Amino_oxidase PF01593.24 EGE09308.1 - 3.7e-44 151.8 0.0 1.3e-43 150.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGE09308.1 - 1.3e-12 47.7 0.0 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EGE09308.1 - 0.00014 22.4 0.4 0.0012 19.3 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGE09308.1 - 0.00015 21.1 0.1 0.00061 19.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGE09308.1 - 0.00021 20.5 0.1 0.0003 20.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGE09308.1 - 0.00038 19.8 1.0 0.00065 19.1 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGE09308.1 - 0.0024 16.6 0.2 0.0036 16.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGE09308.1 - 0.0064 16.1 7.5 0.026 14.1 4.2 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGE09308.1 - 0.0099 15.0 0.3 0.014 14.5 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGE09308.1 - 0.015 15.3 1.1 0.76 9.8 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EGE09308.1 - 0.015 15.2 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGE09308.1 - 0.015 14.3 0.2 0.056 12.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EGE09308.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EGE09308.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGE09308.1 - 0.25 10.6 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 EGE09309.1 - 2.1e-05 24.5 10.0 3.2e-05 23.9 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OCD_Mu_crystall PF02423.15 EGE09310.1 - 4.2e-07 29.2 0.0 0.00014 20.9 0.1 2.3 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Tho2 PF11262.8 EGE09310.1 - 0.019 14.2 0.1 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Aldedh PF00171.22 EGE09311.1 - 1.4e-103 346.9 0.1 1.6e-103 346.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pro_dh PF01619.18 EGE09312.1 - 4.4e-65 220.1 4.2 5.6e-65 219.8 4.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Hydrolase PF00702.26 EGE09312.1 - 0.066 13.5 0.5 4.2 7.6 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Wyosine_form PF08608.12 EGE09313.1 - 5.3e-22 77.9 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EGE09313.1 - 1e-21 78.0 0.0 3.1e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EGE09313.1 - 3.3e-07 30.6 0.2 9.2e-06 25.9 0.2 2.4 1 1 0 1 1 1 1 Flavodoxin MFS_1 PF07690.16 EGE09314.1 - 1.4e-45 155.8 43.5 1.4e-45 155.8 43.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 EGE09314.1 - 0.00016 20.4 0.0 0.00016 20.4 0.0 1.9 3 0 0 3 3 3 1 Ferroportin1 (FPN1) Sugar_tr PF00083.24 EGE09314.1 - 0.00039 19.4 24.0 0.0018 17.2 24.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter ANAPC5 PF12862.7 EGE09315.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 G-alpha PF00503.20 EGE09316.1 - 7.2e-71 239.2 0.1 8.7e-71 238.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGE09316.1 - 1.4e-10 40.9 0.7 6.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family BsuBI_PstI_RE PF06616.11 EGE09316.1 - 0.00084 18.7 0.2 0.0013 18.0 0.2 1.2 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain Gtr1_RagA PF04670.12 EGE09316.1 - 0.0019 17.6 0.1 0.95 8.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 EGE09316.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 EGE09316.1 - 0.029 14.6 0.3 0.94 9.7 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGE09316.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EGE09316.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Spt20 PF12090.8 EGE09317.1 - 0.57 9.8 14.6 0.57 9.7 14.6 1.1 1 0 0 1 1 1 0 Spt20 family Pannexin_like PF12534.8 EGE09317.1 - 1.8 7.5 8.5 1.8 7.5 8.5 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Vfa1 PF08432.10 EGE09317.1 - 2.1 8.6 21.7 2.4 8.5 21.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1764 PF08576.10 EGE09317.1 - 2.9 8.8 21.1 4.2 8.3 21.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) BORG_CEP PF14957.6 EGE09317.1 - 3.5 8.8 9.9 4.1 8.6 9.9 1.2 1 0 0 1 1 1 0 Cdc42 effector MAJIN PF15077.6 EGE09317.1 - 4.4 7.0 14.4 5 6.8 14.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein Rtf2 PF04641.12 EGE09317.1 - 5.3 6.3 23.0 7.2 5.9 23.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CENP-N PF05238.13 EGE09317.1 - 5.4 6.2 13.7 5.8 6.1 13.7 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DDHD PF02862.17 EGE09317.1 - 5.8 7.0 10.6 6.8 6.8 10.6 1.2 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.13 EGE09317.1 - 6 6.6 9.2 6.4 6.5 9.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF3_subunit PF08597.10 EGE09317.1 - 7.1 6.5 26.3 9.3 6.1 26.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TIMELESS PF04821.14 EGE09317.1 - 7.5 5.7 13.6 11 5.2 13.6 1.2 1 0 0 1 1 1 0 Timeless protein Red1 PF07964.11 EGE09317.1 - 8.4 4.5 22.9 9.6 4.3 22.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Peptidase_U57 PF05582.12 EGE09317.1 - 9 5.5 10.6 9.4 5.4 10.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 bZIP_1 PF00170.21 EGE09320.1 - 9.7e-09 35.2 9.7 1.7e-08 34.5 9.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor TMF_TATA_bd PF12325.8 EGE09320.1 - 0.00011 22.3 1.6 0.00016 21.8 1.6 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 EGE09320.1 - 0.0019 18.2 7.2 0.0019 18.2 7.2 2.2 1 1 1 2 2 2 1 Basic region leucine zipper Macoilin PF09726.9 EGE09320.1 - 0.0044 15.7 2.0 0.0054 15.4 2.0 1.1 1 0 0 1 1 1 1 Macoilin family SLATT_4 PF18186.1 EGE09320.1 - 0.0048 16.6 0.3 0.007 16.0 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 ASD2 PF08687.11 EGE09320.1 - 0.0057 16.2 2.5 0.0079 15.8 2.5 1.2 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 bZIP_Maf PF03131.17 EGE09320.1 - 0.0089 16.5 10.5 0.0089 16.5 10.5 1.4 1 1 0 1 1 1 1 bZIP Maf transcription factor SKA1 PF07160.12 EGE09320.1 - 0.013 15.4 1.7 0.018 14.9 1.7 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 HALZ PF02183.18 EGE09320.1 - 0.072 13.3 2.1 0.13 12.5 2.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Q_salvage PF10343.9 EGE09320.1 - 0.082 12.5 0.7 0.11 12.0 0.7 1.1 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family GAS PF13851.6 EGE09320.1 - 0.084 12.2 6.5 0.11 11.9 6.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 EGE09320.1 - 0.11 12.9 3.5 0.25 11.7 3.5 1.6 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS5 PF14817.6 EGE09320.1 - 0.12 11.2 7.1 0.14 10.9 7.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF948 PF06103.11 EGE09320.1 - 0.14 12.5 0.4 0.2 12.0 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) GvpL_GvpF PF06386.11 EGE09320.1 - 0.17 11.8 5.0 0.31 10.9 5.0 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Csm1_N PF18504.1 EGE09320.1 - 0.31 11.4 5.7 0.72 10.2 1.8 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain EMP24_GP25L PF01105.24 EGE09320.1 - 0.52 10.2 2.6 0.69 9.8 2.6 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spermine_synth PF01564.17 EGE09321.1 - 3.8e-65 218.8 0.0 5.1e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGE09321.1 - 3e-23 81.4 0.1 5.6e-23 80.6 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGE09321.1 - 9.5e-05 23.0 0.0 0.00025 21.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE09321.1 - 0.00084 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE09321.1 - 0.0012 19.5 0.2 0.0058 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EGE09321.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain MTS PF05175.14 EGE09321.1 - 0.063 12.8 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EGE09321.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_N PF00456.21 EGE09322.1 - 6.6e-152 505.3 0.0 8.6e-152 504.9 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGE09322.1 - 4e-46 156.9 0.0 6.6e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGE09322.1 - 4.5e-12 45.9 0.0 9.6e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EGE09322.1 - 1.8e-05 24.1 0.0 4.8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EGE09322.1 - 0.035 13.1 0.3 0.055 12.4 0.3 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 EGE09322.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase TPP_enzyme_C PF02775.21 EGE09322.1 - 0.68 9.7 8.5 0.12 12.2 1.7 2.6 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fungal_trans PF04082.18 EGE09323.1 - 2.2e-31 108.9 0.7 3.3e-31 108.3 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE09323.1 - 9.9e-10 38.4 11.7 1.5e-09 37.8 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EGE09323.1 - 0.018 14.6 1.5 0.045 13.3 1.5 1.6 1 0 0 1 1 1 0 Trimerisation motif bZIP_1 PF00170.21 EGE09323.1 - 0.41 10.8 0.1 0.41 10.8 0.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 EGE09323.1 - 1.9 8.4 5.0 0.8 9.6 1.3 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SET PF00856.28 EGE09325.1 - 0.0015 19.0 0.0 0.0037 17.6 0.0 1.8 2 1 0 2 2 2 1 SET domain MMR_HSR1_C PF08438.10 EGE09327.1 - 1.4e-36 125.4 0.0 3.1e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGE09327.1 - 1.5e-17 63.7 0.0 6.8e-17 61.6 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGE09327.1 - 1.9e-05 24.2 0.0 0.00065 19.3 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGE09327.1 - 0.0062 16.5 1.4 0.13 12.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGE09327.1 - 0.0073 15.9 1.0 0.57 9.7 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGE09327.1 - 0.024 14.4 0.1 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGE09327.1 - 0.051 14.1 0.3 0.83 10.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 EGE09327.1 - 0.051 12.5 0.4 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGE09327.1 - 0.068 13.2 2.4 0.29 11.2 0.5 2.5 3 0 0 3 3 3 0 Dynamin family Ploopntkinase3 PF18751.1 EGE09327.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 EGE09327.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 EGE09327.1 - 0.12 11.7 0.1 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1_Xtn PF16897.5 EGE09327.1 - 0.13 12.3 0.2 0.34 11.0 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain FSIP1 PF15554.6 EGE09328.1 - 0.22 10.6 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 FSIP1 family Ribosomal_L7Ae PF01248.26 EGE09330.1 - 3.2e-18 65.2 1.3 3.2e-18 65.2 1.3 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rib_recp_KP_reg PF05104.12 EGE09330.1 - 0.013 16.5 15.5 0.013 16.5 15.5 2.2 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region UcrQ PF02939.16 EGE09331.1 - 2.3e-33 114.0 0.4 2.6e-33 113.8 0.4 1.0 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 EGE09332.1 - 1.8e-24 86.8 8.1 4.1e-24 85.6 8.1 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGE09332.1 - 0.00088 18.4 4.2 0.0012 17.9 4.2 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 EGE09332.1 - 0.023 14.6 0.6 0.04 13.8 0.6 1.4 1 0 0 1 1 1 0 GatB domain DUF2228 PF10228.9 EGE09333.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Methyltransf_34 PF11312.8 EGE09334.1 - 6.3e-101 337.6 0.0 9.2e-101 337.1 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase PAF-AH_p_II PF03403.13 EGE09335.1 - 6.5e-16 57.8 0.0 3.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGE09335.1 - 2.3e-05 23.4 0.0 3.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EGE09335.1 - 2.3e-05 23.8 0.0 0.088 12.1 0.1 2.4 2 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EGE09335.1 - 0.018 14.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGE09335.1 - 0.068 12.8 0.1 0.42 10.2 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EGE09335.1 - 0.11 11.5 0.1 0.2 10.6 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase AP_endonuc_2 PF01261.24 EGE09335.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Nop14 PF04147.12 EGE09336.1 - 0.014 13.6 6.2 0.025 12.8 6.2 1.4 1 0 0 1 1 1 0 Nop14-like family DUF202 PF02656.15 EGE09340.1 - 5.2e-22 78.1 0.3 5.2e-22 78.1 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.15 EGE09342.1 - 7.8e-105 350.6 0.0 9.1e-105 350.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1754 PF08555.10 EGE09343.1 - 1.7e-15 57.6 19.5 1.7e-15 57.6 19.5 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 EGE09343.1 - 0.047 13.1 15.6 0.052 12.9 15.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 EccE PF11203.8 EGE09343.1 - 0.2 12.0 3.5 0.12 12.7 1.2 1.6 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE LAM_C PF12544.8 EGE09343.1 - 0.23 11.6 3.2 0.33 11.1 3.2 1.2 1 0 0 1 1 1 0 Lysine-2,3-aminomutase G-gamma PF00631.22 EGE09343.1 - 0.56 10.2 2.5 0.73 9.9 0.5 2.1 2 0 0 2 2 2 0 GGL domain HSP70 PF00012.20 EGE09343.1 - 1.3 7.2 12.6 1.5 6.9 12.6 1.0 1 0 0 1 1 1 0 Hsp70 protein CDC45 PF02724.14 EGE09343.1 - 3.1 6.0 18.3 3.5 5.8 18.3 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-AN1 PF01428.16 EGE09344.1 - 2.3e-13 50.1 4.2 2.3e-13 50.1 4.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGE09344.1 - 0.01 16.1 4.0 0.01 16.1 4.0 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DLH PF01738.18 EGE09346.1 - 4.4e-15 55.8 0.0 6.5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGE09346.1 - 0.0094 15.6 0.0 0.036 13.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold AA_permease_2 PF13520.6 EGE09348.1 - 3.1e-57 194.3 51.2 3.6e-57 194.1 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE09348.1 - 1.4e-25 89.8 44.7 1.9e-25 89.4 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF962 PF06127.11 EGE09348.1 - 0.25 11.5 7.8 2 8.5 0.0 3.9 3 3 0 3 3 3 0 Protein of unknown function (DUF962) p450 PF00067.22 EGE09349.1 - 1.7e-49 168.9 0.0 1.2e-48 166.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF3965 PF13112.6 EGE09349.1 - 0.1 11.8 0.3 9.3 5.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3965) Choline_kinase PF01633.20 EGE09350.1 - 3.8e-12 46.2 0.0 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGE09350.1 - 1.2e-11 45.0 0.0 1.6e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ClpS PF02617.17 EGE09350.1 - 0.06 13.1 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS LPD11 PF18824.1 EGE09350.1 - 0.063 13.4 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 PH_TFIIH PF08567.11 EGE09352.1 - 4.6e-24 84.5 0.0 1.1e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 EGE09352.1 - 4.5e-23 81.0 7.7 3.1e-11 43.1 0.0 3.0 3 0 0 3 3 3 2 BSD domain TetR PF13972.6 EGE09352.1 - 0.081 12.6 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial transcriptional repressor Anillin_N PF16018.5 EGE09352.1 - 0.092 13.4 0.6 7.7 7.2 0.1 2.8 2 0 0 2 2 2 0 Anillin N-terminus PIN_8 PF18476.1 EGE09352.1 - 0.13 12.1 2.5 0.13 12.1 0.2 2.2 2 0 0 2 2 2 0 PIN like domain DUF1751 PF08551.10 EGE09353.1 - 0.0022 18.6 1.3 0.0041 17.7 0.6 1.9 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.7 EGE09354.1 - 4.2e-09 36.9 0.1 9.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGE09354.1 - 2.2e-06 27.5 6.9 3.6e-06 26.8 6.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EGE09354.1 - 0.043 13.4 2.6 0.074 12.6 2.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EGE09354.1 - 0.17 12.2 2.0 0.34 11.2 2.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4504 PF14953.6 EGE09354.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) Transket_pyr PF02779.24 EGE09355.1 - 1.7e-66 223.3 0.0 2.8e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGE09355.1 - 1.8e-56 190.1 0.0 3e-56 189.3 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGE09355.1 - 3e-56 190.6 0.0 4.6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EGE09355.1 - 3.1e-20 71.5 0.6 3.1e-20 71.5 0.6 1.8 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus VPS13_mid_rpt PF16910.5 EGE09357.1 - 7.5e-93 310.3 10.9 6.4e-87 290.9 0.3 5.7 5 0 0 5 5 5 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 EGE09357.1 - 1.1e-92 310.2 0.0 4.1e-91 305.1 0.0 3.1 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EGE09357.1 - 6.6e-80 268.3 4.7 1e-78 264.4 0.0 4.4 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGE09357.1 - 3.5e-73 245.2 8.8 4.4e-70 235.1 0.3 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EGE09357.1 - 1.2e-40 138.3 0.0 3.6e-40 136.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGE09357.1 - 5e-06 26.8 0.2 2.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF896 PF05979.12 EGE09357.1 - 2.3 8.1 4.7 1.1 9.2 0.8 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.8 EGE09359.1 - 9.2e-44 149.2 13.1 1.4e-43 148.6 13.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 EGE09360.1 - 2.2e-71 239.7 0.5 8.1e-71 237.8 0.4 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EGE09360.1 - 4e-42 144.5 0.1 1.5e-25 90.2 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EGE09360.1 - 0.053 13.0 0.2 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 EGE09361.1 - 4.5e-54 183.2 0.1 8e-54 182.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGE09361.1 - 3.3e-42 144.0 0.0 7e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGE09361.1 - 2e-08 33.9 0.0 5.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGE09361.1 - 2.7e-05 24.2 0.0 7.9e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGE09361.1 - 6.9e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EGE09361.1 - 9.9e-05 22.1 0.0 0.0021 17.8 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGE09361.1 - 9.9e-05 22.8 2.9 0.00047 20.6 0.6 3.0 3 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EGE09361.1 - 0.00012 22.3 0.2 0.014 15.7 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGE09361.1 - 0.0017 18.5 0.0 0.0055 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGE09361.1 - 0.0052 16.9 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 EGE09361.1 - 0.0085 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGE09361.1 - 0.014 15.9 0.0 0.054 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EGE09361.1 - 0.018 14.6 1.7 0.75 9.3 0.2 2.4 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGE09361.1 - 0.021 14.2 0.3 0.044 13.2 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EGE09361.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase PF06745.13 EGE09361.1 - 0.037 13.4 0.1 1.6 8.0 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 EGE09361.1 - 0.049 13.9 0.4 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGE09361.1 - 0.062 13.2 0.4 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EGE09361.1 - 0.086 12.8 0.0 0.34 10.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGE09361.1 - 0.1 12.6 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EGE09361.1 - 0.15 12.4 0.2 0.45 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGE09361.1 - 0.18 11.1 0.8 0.7 9.1 0.5 2.1 1 1 1 2 2 2 0 Zeta toxin NTP_transferase PF00483.23 EGE09363.1 - 4.2e-52 177.2 0.0 7.3e-52 176.4 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EGE09363.1 - 1.6e-15 56.1 9.8 1.2e-10 40.7 3.0 4.0 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGE09363.1 - 2.2e-09 37.9 0.0 2.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGE09363.1 - 2e-06 27.4 1.3 2e-06 27.4 1.3 3.5 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGE09363.1 - 0.0027 15.9 0.1 0.0069 14.6 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 EGE09363.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase LPMO_10 PF03067.15 EGE09367.1 - 0.011 16.4 0.1 0.038 14.6 0.1 1.8 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Mo-co_dimer PF03404.16 EGE09368.1 - 3.5e-58 195.5 0.5 6.2e-58 194.7 0.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EGE09368.1 - 5.5e-54 182.4 0.0 9.3e-54 181.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain NAD_binding_1 PF00175.21 EGE09368.1 - 1.5e-27 96.4 0.0 9.8e-27 93.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EGE09368.1 - 1.1e-18 67.2 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 EGE09368.1 - 3.6e-17 62.5 0.0 6.6e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGE09368.1 - 0.0005 20.2 0.1 0.009 16.1 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Sec5 PF15469.6 EGE09369.1 - 2.4e-35 122.1 0.0 4.3e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EGE09369.1 - 4.5e-05 23.5 0.4 0.00012 22.1 0.4 1.7 1 0 0 1 1 1 1 Vps51/Vps67 DUF802 PF05650.11 EGE09369.1 - 0.67 10.5 4.0 0.25 11.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Iso_dh PF00180.20 EGE09370.1 - 1.9e-101 339.7 0.0 2.4e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EGE09370.1 - 0.0088 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 Eaf7 PF07904.13 EGE09371.1 - 4.2e-29 101.0 0.0 8.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 GCP_C_terminal PF04130.13 EGE09372.1 - 3.2e-67 227.2 0.0 4.4e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGE09372.1 - 2e-32 113.1 0.0 2.3e-31 109.6 0.0 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal rRNA_processing PF08524.11 EGE09373.1 - 0.00079 19.5 11.6 0.00079 19.5 11.6 2.5 1 1 1 2 2 2 1 rRNA processing Serglycin PF04360.12 EGE09373.1 - 0.031 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Serglycin Chromosome_seg PF13889.6 EGE09374.1 - 5.1e-22 77.8 0.2 1.1e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.19 EGE09375.1 - 3e-113 378.5 0.5 4e-113 378.1 0.0 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGE09375.1 - 1.4e-54 184.0 1.6 1.9e-54 183.5 1.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGE09375.1 - 0.06 13.1 3.3 1.6 8.5 2.6 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Ribosomal_60s PF00428.19 EGE09375.1 - 2.3 8.9 8.3 0.28 11.8 1.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein PfkB PF00294.24 EGE09376.1 - 3e-11 43.2 0.0 5.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.6 EGE09378.1 - 8.5e-07 29.2 0.0 0.0042 17.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 EGE09378.1 - 5.2e-06 27.1 0.0 9.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EGE09378.1 - 0.00013 22.5 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain BSP PF04450.12 EGE09380.1 - 5.1e-65 219.1 0.0 6e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 EGE09381.1 - 1.2e-150 499.4 3.6 1.1e-92 309.7 0.0 3.0 3 1 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.7 EGE09381.1 - 2.5e-06 27.6 0.0 0.044 13.8 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGE09381.1 - 5.5e-06 26.2 0.7 5.3 7.6 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Acetyltransf_8 PF13523.6 EGE09382.1 - 1e-43 148.5 0.6 1.4e-43 148.0 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EGE09384.1 - 1.2e-89 300.6 32.5 1.8e-46 159.0 10.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGE09384.1 - 4.2e-66 221.6 0.0 6.9e-32 110.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGE09384.1 - 3.3e-16 59.4 2.5 1.9e-05 24.2 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGE09384.1 - 3.7e-10 39.2 0.3 0.0012 17.8 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EGE09384.1 - 4.7e-09 35.8 0.7 0.002 17.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGE09384.1 - 7.4e-08 33.0 0.7 0.002 18.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGE09384.1 - 9.5e-08 32.4 2.1 0.098 12.9 0.0 4.1 3 1 0 4 4 3 2 AAA domain DUF87 PF01935.17 EGE09384.1 - 1.7e-07 31.6 0.4 0.0013 18.9 0.0 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_15 PF13175.6 EGE09384.1 - 1.3e-05 25.1 0.0 0.058 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EGE09384.1 - 6e-05 22.8 1.3 0.13 11.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGE09384.1 - 7.9e-05 22.6 0.0 0.58 10.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF3987 PF13148.6 EGE09384.1 - 0.00022 20.4 0.0 0.16 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_21 PF13304.6 EGE09384.1 - 0.00035 20.5 1.3 4.4 7.0 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGE09384.1 - 0.0007 20.2 0.0 0.42 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EGE09384.1 - 0.00077 20.0 0.5 2.2 8.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EGE09384.1 - 0.0011 18.2 0.5 0.66 9.2 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 EGE09384.1 - 0.0023 17.1 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 EGE09384.1 - 0.0025 18.0 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EGE09384.1 - 0.0036 16.7 0.0 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.14 EGE09384.1 - 0.006 16.6 0.1 6.7 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EGE09384.1 - 0.0094 15.6 1.1 0.8 9.3 0.0 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EGE09384.1 - 0.011 15.4 0.0 3 7.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EGE09384.1 - 0.018 15.3 0.2 3.8 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGE09384.1 - 0.019 14.7 0.1 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGE09384.1 - 0.027 13.4 0.1 1.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.6 EGE09384.1 - 0.045 14.0 4.8 4.8 7.5 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGE09384.1 - 0.068 12.9 0.7 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 EGE09384.1 - 0.07 13.0 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MTH865 PF07747.11 EGE09384.1 - 0.081 12.7 0.0 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 MTH865-like family AAA_7 PF12775.7 EGE09384.1 - 0.084 12.4 0.0 13 5.2 0.0 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGE09384.1 - 0.11 13.0 0.1 25 5.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGE09384.1 - 0.17 12.0 0.1 28 4.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase FERM_N PF09379.10 EGE09384.1 - 0.17 11.8 0.1 0.55 10.2 0.1 1.9 1 0 0 1 1 1 0 FERM N-terminal domain ATP_bind_1 PF03029.17 EGE09384.1 - 0.3 10.8 1.7 12 5.6 0.0 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein COX5A PF02284.16 EGE09385.1 - 2.1e-38 130.5 0.8 2.7e-38 130.1 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4972 PF16342.5 EGE09385.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) WD40_4 PF16300.5 EGE09385.1 - 0.13 12.2 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Type of WD40 repeat Merozoite_SPAM PF07133.11 EGE09386.1 - 0.96 9.4 21.2 1.1 9.2 21.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PBP1_TM PF14812.6 EGE09386.1 - 3.2 8.2 18.5 4.4 7.8 18.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_Rpc4 PF05132.14 EGE09386.1 - 3.4 8.1 10.0 4 7.9 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.6 EGE09386.1 - 6.9 6.8 9.9 8.2 6.6 9.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.12 EGE09386.1 - 9.5 6.0 18.1 10 5.8 18.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ELO PF01151.18 EGE09387.1 - 5.9e-63 212.7 19.9 7.1e-63 212.4 19.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5087 PF17006.5 EGE09388.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) AA_permease_2 PF13520.6 EGE09390.1 - 8.3e-41 140.2 50.5 1.1e-40 139.8 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE09390.1 - 9.8e-17 60.7 40.6 1.3e-16 60.2 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 EGE09391.1 - 2.1e-62 210.8 0.0 2.7e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGE09391.1 - 2.6e-52 177.1 0.3 3.3e-52 176.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGE09391.1 - 5.3e-05 23.2 0.8 0.00015 21.8 0.8 1.6 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 EGE09391.1 - 0.04 12.6 0.2 0.048 12.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1996 PF09362.10 EGE09392.1 - 3.3e-85 285.8 0.0 6e-85 285.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) AdoMet_MTase PF07757.13 EGE09392.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase G-alpha PF00503.20 EGE09394.1 - 1.9e-16 60.2 0.6 2.1e-16 60.1 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGE09394.1 - 0.00028 20.4 0.1 0.00035 20.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.6 EGE09394.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EGE09394.1 - 0.024 14.6 0.3 0.026 14.5 0.3 1.0 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 EGE09394.1 - 0.029 13.8 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EGE09394.1 - 0.04 13.3 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family WAK PF08488.11 EGE09394.1 - 0.055 14.0 0.0 0.058 13.9 0.0 1.0 1 0 0 1 1 1 0 Wall-associated kinase Roc PF08477.13 EGE09394.1 - 0.082 13.1 0.4 0.11 12.7 0.1 1.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF498 PF04430.14 EGE09394.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) DUF3464 PF11947.8 EGE09396.1 - 0.24 11.1 1.5 0.33 10.7 1.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pkinase PF00069.25 EGE09397.1 - 3.2e-67 226.7 0.0 4.1e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09397.1 - 2.1e-32 112.4 0.0 2.9e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGE09397.1 - 1.3e-05 24.3 0.1 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGE09397.1 - 9.6e-05 21.8 0.1 0.0003 20.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGE09397.1 - 0.00045 19.6 0.0 0.026 13.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGE09397.1 - 0.00069 19.6 0.0 0.0026 17.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGE09397.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGE09397.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 EGE09398.1 - 1.1e-143 478.5 0.0 1.5e-143 478.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EGE09398.1 - 6.2e-08 32.6 0.1 0.00048 20.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EGE09398.1 - 1.9e-07 31.0 8.4 7.4e-06 25.8 0.5 3.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Menin PF05053.13 EGE09398.1 - 1.7 6.9 14.4 2.4 6.4 14.4 1.1 1 0 0 1 1 1 0 Menin Afi1 PF07792.12 EGE09398.1 - 3.3 8.2 8.8 4.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cullin PF00888.22 EGE09399.1 - 4.5e-118 395.5 1.9 1.2e-72 245.4 1.4 2.2 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EGE09399.1 - 1.5e-27 95.4 2.3 5.5e-27 93.6 2.3 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain Cupin_1 PF00190.22 EGE09400.1 - 1e-10 41.4 0.1 1.4e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EGE09400.1 - 4.5e-08 32.7 0.1 7.1e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 EGE09400.1 - 0.00035 20.8 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 EGE09400.1 - 0.00056 19.7 0.1 0.00068 19.4 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EGE09400.1 - 0.0021 18.0 0.1 0.0025 17.7 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain MARVEL PF01284.23 EGE09401.1 - 0.0037 17.3 2.7 0.0075 16.3 2.7 1.5 1 0 0 1 1 1 1 Membrane-associating domain KcnmB2_inactiv PF09303.10 EGE09401.1 - 0.0089 15.8 0.5 0.034 13.9 0.5 2.1 1 0 0 1 1 1 1 KCNMB2, ball and chain domain PAP1 PF08601.10 EGE09401.1 - 0.087 12.5 12.9 0.13 12.0 12.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF1418 PF07214.12 EGE09401.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Mit_KHE1 PF10173.9 EGE09402.1 - 2.5e-66 223.4 0.7 2.5e-66 223.4 0.7 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SCAB_CC PF16712.5 EGE09402.1 - 0.0015 18.4 0.7 0.14 12.0 0.1 2.2 2 0 0 2 2 2 2 Coiled-coil regions of plant-specific actin-binding protein ABC2_membrane_4 PF12730.7 EGE09402.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein End3 PF12761.7 EGE09403.1 - 1.1e-72 244.3 1.5 1.5e-72 243.9 1.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EGE09403.1 - 2.4e-51 172.0 0.1 5e-49 164.6 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGE09403.1 - 8.5e-08 31.2 0.2 2.6e-07 29.7 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGE09403.1 - 1.2e-06 28.9 0.7 6.1e-06 26.6 0.1 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGE09403.1 - 9.6e-05 22.0 0.5 0.00043 20.0 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGE09403.1 - 0.0016 18.2 0.2 0.0053 16.6 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGE09403.1 - 0.0029 17.0 1.0 0.0094 15.4 0.2 2.2 2 0 0 2 2 2 1 EF hand NPV_P10 PF05531.12 EGE09403.1 - 0.016 15.7 0.2 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA1 PF07160.12 EGE09403.1 - 0.027 14.3 0.3 0.053 13.4 0.3 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 EGE09403.1 - 0.075 12.4 5.2 0.11 11.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EGE09403.1 - 0.88 9.7 4.6 2.3 8.3 0.6 2.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EGE09403.1 - 1.6 7.6 11.5 0.26 10.1 4.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Wtap PF17098.5 EGE09403.1 - 2.3 8.1 9.6 2 8.3 7.8 1.7 2 0 0 2 2 2 0 WTAP/Mum2p family Sec2p PF06428.11 EGE09403.1 - 2.4 8.2 10.2 7.6 6.6 0.9 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Med9 PF07544.13 EGE09403.1 - 3.4 7.8 5.8 0.48 10.6 0.2 2.4 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 SNF2_N PF00176.23 EGE09404.1 - 5.4e-63 212.8 0.1 5.4e-63 212.8 0.1 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE09404.1 - 8e-22 77.7 0.2 1.3e-20 73.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EGE09404.1 - 1.5e-05 24.4 2.4 0.0062 15.7 0.0 4.0 3 1 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Spt20 PF12090.8 EGE09404.1 - 2.6 7.6 13.1 7.5 6.1 13.1 1.8 1 0 0 1 1 1 0 Spt20 family Shugoshin_C PF07557.11 EGE09404.1 - 3.1 7.7 6.6 3.6 7.5 3.1 2.7 2 0 0 2 2 2 0 Shugoshin C terminus Ribosomal_L5e PF17144.4 EGE09405.1 - 0.1 12.5 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal large subunit proteins 60S L5, and 50S L18 DSPc PF00782.20 EGE09406.1 - 5.2e-12 45.7 0.0 1.5e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGE09406.1 - 7.5e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain AI-2E_transport PF01594.16 EGE09406.1 - 0.2 10.8 0.0 7.2 5.7 0.0 2.1 2 0 0 2 2 2 0 AI-2E family transporter zf-C2H2 PF00096.26 EGE09407.1 - 5.8e-09 35.9 12.0 0.00055 20.2 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EGE09407.1 - 7.6e-05 22.9 0.9 0.00013 22.1 0.1 1.7 2 0 0 2 2 2 1 Aberrant zinc-finger Spc29 PF17082.5 EGE09407.1 - 0.00045 20.1 0.2 0.00077 19.4 0.2 1.3 1 0 0 1 1 1 1 Spindle Pole Component 29 APC_N_CC PF16689.5 EGE09407.1 - 0.0087 16.1 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain zf-C2H2_4 PF13894.6 EGE09407.1 - 0.012 16.4 7.5 7.5 7.7 0.1 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGE09407.1 - 0.03 14.8 10.3 3.8 8.1 0.5 3.8 3 0 0 3 3 3 0 Zinc-finger double domain ATG16 PF08614.11 EGE09407.1 - 0.031 14.5 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Transpos_assoc PF13963.6 EGE09407.1 - 0.13 12.6 1.5 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Transposase-associated domain Cep57_MT_bd PF06657.13 EGE09407.1 - 0.14 12.6 2.5 8.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MPS2 PF17060.5 EGE09407.1 - 0.31 10.3 0.5 0.43 9.8 0.5 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Lebercilin PF15619.6 EGE09407.1 - 0.58 9.8 4.9 0.55 9.9 1.0 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease WD40 PF00400.32 EGE09408.1 - 2.7e-48 160.9 18.5 9e-09 35.8 0.3 8.6 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE09408.1 - 7.6e-11 42.2 0.0 0.00017 21.8 0.0 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGE09408.1 - 5e-07 28.7 0.0 0.035 12.7 0.0 3.8 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGE09408.1 - 0.00011 21.1 0.0 0.02 13.7 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Pox_A_type_inc PF04508.12 EGE09408.1 - 0.086 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Rx_N PF18052.1 EGE09408.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Rx N-terminal domain p450 PF00067.22 EGE09409.1 - 3.1e-69 233.9 0.0 3.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.6 EGE09409.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal A_deaminase PF00962.22 EGE09410.1 - 7.9e-25 87.9 0.0 9.2e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Urb2 PF10441.9 EGE09411.1 - 6.5e-64 215.6 4.6 2.1e-63 214.0 0.0 3.1 3 0 0 3 3 3 1 Urb2/Npa2 family DUF543 PF04418.12 EGE09412.1 - 1.5e-27 95.4 0.0 1.7e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Copper-fist PF00649.18 EGE09413.1 - 1.2e-17 63.1 0.4 1.2e-17 63.1 0.4 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF4805 PF16063.5 EGE09413.1 - 0.0067 15.8 6.1 0.02 14.3 6.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4805) SUIM_assoc PF16619.5 EGE09413.1 - 0.022 14.8 6.3 0.022 14.8 6.3 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Metallothio_2 PF01439.18 EGE09413.1 - 0.072 14.0 22.1 0.1 13.5 7.0 3.6 3 0 0 3 3 3 0 Metallothionein GST_C_6 PF17171.4 EGE09414.1 - 7.7e-20 70.5 0.1 1.4e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE09414.1 - 4.5e-19 69.0 0.0 1.1e-18 67.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGE09414.1 - 4.1e-11 43.3 0.0 1.2e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EGE09414.1 - 6.3e-06 26.5 0.1 1.9e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EGE09414.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CENP-B_dimeris PF09026.10 EGE09414.1 - 0.042 14.2 8.5 0.08 13.3 8.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EGE09414.1 - 0.086 13.2 4.8 0.17 12.3 4.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TALPID3 PF15324.6 EGE09414.1 - 0.18 9.4 2.3 0.25 9.0 2.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target NOA36 PF06524.12 EGE09414.1 - 2.3 7.4 8.8 3.6 6.8 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein Methyltransf_25 PF13649.6 EGE09415.1 - 7.9e-16 58.6 0.0 1.6e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGE09415.1 - 2.7e-15 56.8 0.0 4.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGE09415.1 - 1.5e-13 50.8 0.0 1.9e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGE09415.1 - 8.5e-13 48.9 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGE09415.1 - 1.5e-12 47.7 0.0 2.2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGE09415.1 - 1.5e-05 24.4 0.0 4.1e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGE09415.1 - 4.2e-05 23.0 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGE09415.1 - 6.2e-05 22.6 0.0 0.00045 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.26 EGE09415.1 - 0.00084 19.3 0.0 0.0033 17.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.19 EGE09415.1 - 0.0049 16.6 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EGE09415.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Pox_MCEL PF03291.16 EGE09415.1 - 0.013 14.6 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme TehB PF03848.14 EGE09415.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EGE09415.1 - 0.03 14.3 0.0 0.048 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain VBS PF08913.10 EGE09415.1 - 0.043 14.3 0.0 0.18 12.2 0.0 2.0 2 1 0 2 2 2 0 Vinculin Binding Site Methyltransf_7 PF03492.15 EGE09415.1 - 0.053 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DOT1 PF08123.13 EGE09415.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 EGE09415.1 - 0.2 11.5 0.0 0.7 9.7 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase CDC14 PF08045.11 EGE09416.1 - 1.1e-130 434.9 0.0 1.2e-130 434.7 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component TOH_N PF12549.8 EGE09416.1 - 0.058 13.3 3.6 0.19 11.6 3.6 1.9 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal FoP_duplication PF13865.6 EGE09417.1 - 0.58 10.7 6.6 1.1 9.8 6.6 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sugar_tr PF00083.24 EGE09419.1 - 7.9e-78 262.3 17.1 9.6e-78 262.0 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGE09419.1 - 1.8e-14 53.4 31.4 3.4e-14 52.5 31.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_4 PF01063.19 EGE09420.1 - 1.9e-14 54.1 0.0 2.7e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Amino-transferase class IV Cyclin PF08613.11 EGE09421.1 - 1.2e-06 29.0 0.5 6.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGE09421.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_1 PF00076.22 EGE09422.1 - 6.1e-08 32.4 0.0 9.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EGE09422.1 - 1.5e-05 25.4 0.8 2.6e-05 24.7 0.8 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EGE09422.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ank_2 PF12796.7 EGE09424.1 - 5.1e-72 238.5 0.4 3.4e-16 59.6 0.5 8.4 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGE09424.1 - 4.9e-54 180.0 0.0 3.4e-13 49.8 0.0 11.3 6 2 5 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGE09424.1 - 1.2e-47 154.4 2.0 1.5e-05 24.9 0.0 15.6 17 1 1 18 18 16 8 Ankyrin repeat Ank PF00023.30 EGE09424.1 - 4.8e-41 137.4 8.3 1.1e-05 25.7 0.0 12.5 12 1 1 13 13 11 7 Ankyrin repeat Ank_5 PF13857.6 EGE09424.1 - 5.8e-39 131.6 5.1 9.1e-08 32.2 0.0 12.3 5 4 8 13 13 13 6 Ankyrin repeats (many copies) HeLo PF14479.6 EGE09424.1 - 1.7e-08 34.6 0.0 0.00064 19.6 0.1 2.6 1 1 0 2 2 2 2 Prion-inhibition and propagation NACHT PF05729.12 EGE09424.1 - 2.7e-06 27.4 0.0 5.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EGE09424.1 - 7.6e-05 23.0 0.0 0.0003 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGE09424.1 - 0.0012 18.1 0.1 0.012 14.9 0.1 2.1 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGE09424.1 - 0.0016 18.8 0.0 0.0045 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGE09424.1 - 0.0032 17.8 0.0 0.0084 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase VWA_3_C PF18571.1 EGE09424.1 - 0.011 15.5 0.3 0.33 10.9 0.1 3.0 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain ATPase_2 PF01637.18 EGE09424.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EGE09424.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Glyco_hydro_72 PF03198.14 EGE09425.1 - 3.6e-121 404.2 0.1 4.8e-121 403.8 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EGE09425.1 - 2.6e-05 23.8 0.0 0.00061 19.3 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.15 EGE09426.1 - 6.9e-44 149.1 0.3 8.1e-44 148.8 0.3 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Exo84_C PF16528.5 EGE09427.1 - 9.5e-69 231.3 0.1 9.5e-69 231.3 0.1 2.2 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGE09427.1 - 4.2e-16 58.8 1.9 4.2e-16 58.8 1.9 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 EGE09427.1 - 0.0017 18.4 3.0 0.003 17.6 0.1 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2594 PF10769.9 EGE09427.1 - 0.022 14.8 0.1 0.049 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF4088 PF13317.6 EGE09427.1 - 0.11 12.0 1.7 0.37 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) 7TMR-HDED PF07697.11 EGE09427.1 - 0.11 12.5 8.8 0.11 12.6 3.2 2.2 2 0 0 2 2 2 0 7TM-HD extracellular HIP1_clath_bdg PF16515.5 EGE09427.1 - 0.48 11.1 8.9 1.2 9.8 3.0 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 EGE09427.1 - 0.89 8.9 6.9 0.7 9.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EGE09427.1 - 0.96 9.5 4.8 0.45 10.6 0.3 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 EGE09427.1 - 2.8 8.0 13.3 1.2 9.2 2.1 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 EGE09427.1 - 5 6.6 11.0 0.96 8.9 5.2 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain BST2 PF16716.5 EGE09427.1 - 6.1 7.5 6.8 17 6.1 1.3 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ABC_tran PF00005.27 EGE09428.1 - 1.1e-19 71.3 0.0 1.1e-09 39.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGE09428.1 - 0.0001 22.2 4.5 0.05 13.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGE09428.1 - 0.00049 20.3 0.0 0.055 13.7 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 EGE09428.1 - 0.17 9.4 0.1 0.38 8.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NB-ARC PF00931.22 EGE09428.1 - 0.19 10.9 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain CPSase_L_D2 PF02786.17 EGE09429.1 - 2.2e-115 383.5 0.4 7.5e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGE09429.1 - 2.3e-49 166.4 0.0 4.6e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EGE09429.1 - 2.3e-46 158.0 0.0 1.2e-45 155.6 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EGE09429.1 - 7.7e-46 155.8 0.1 1.7e-45 154.6 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EGE09429.1 - 1.1e-38 132.4 0.0 2.6e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGE09429.1 - 4.8e-32 111.2 0.0 1.4e-31 109.7 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EGE09429.1 - 3.1e-22 78.6 0.0 1.4e-21 76.5 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EGE09429.1 - 1.2e-18 67.5 0.8 4.4e-09 36.2 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGE09429.1 - 8.5e-17 61.2 0.1 4.1e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EGE09429.1 - 2.9e-10 40.0 0.0 4.5e-05 23.2 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EGE09429.1 - 2.4e-06 27.7 0.7 0.019 15.0 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGE09429.1 - 7.1e-05 22.7 0.1 0.0056 16.5 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EGE09429.1 - 0.00028 20.7 0.2 0.26 11.1 0.0 4.0 5 0 0 5 5 4 1 DJ-1/PfpI family RimK PF08443.11 EGE09429.1 - 0.0013 18.3 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 EGE09429.1 - 0.0022 17.8 0.1 1.8 8.3 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EGE09429.1 - 0.095 13.0 0.1 0.68 10.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Ion_trans PF00520.31 EGE09430.1 - 3.3e-08 33.0 27.6 5.2e-08 32.4 27.6 1.2 1 0 0 1 1 1 1 Ion transport protein Synaptobrevin PF00957.21 EGE09431.1 - 1.1e-31 108.5 0.0 1.5e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGE09431.1 - 1.1e-29 102.3 0.4 1.8e-29 101.6 0.1 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Ribosomal_L26 PF16906.5 EGE09432.1 - 2.8e-39 133.4 3.3 3.5e-39 133.1 3.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGE09432.1 - 9.7e-09 34.9 2.1 2e-08 33.9 2.1 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 EGE09432.1 - 0.011 15.7 0.1 0.013 15.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) ARL17 PF15840.5 EGE09433.1 - 0.07 13.5 1.2 0.2 12.0 1.2 1.8 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 zf-C2H2_4 PF13894.6 EGE09433.1 - 6.9 7.8 6.2 71 4.6 2.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DFRP_C PF16543.5 EGE09434.1 - 1.5e-25 89.5 11.0 1.5e-25 89.5 11.0 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGE09434.1 - 4.9e-06 27.2 4.5 4.9e-06 27.2 4.5 4.1 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 EGE09434.1 - 5.8e-05 22.8 10.2 0.00087 19.0 2.7 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGE09434.1 - 0.00033 20.5 1.3 0.00033 20.5 1.3 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGE09434.1 - 0.0012 18.8 6.7 0.0012 18.8 6.7 3.3 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_3 PF15663.5 EGE09434.1 - 0.1 12.8 6.2 0.58 10.4 0.9 2.7 1 1 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGE09434.1 - 0.24 11.9 14.5 0.32 11.5 4.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PDZ_5 PF17817.1 EGE09435.1 - 0.15 12.4 1.4 17 5.8 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Snf7 PF03357.21 EGE09436.1 - 1.1e-20 73.9 13.9 1.1e-20 73.9 11.3 1.8 1 1 1 2 2 2 1 Snf7 MerR-DNA-bind PF09278.11 EGE09436.1 - 1.2 9.8 11.4 4.3 7.9 0.9 3.7 4 0 0 4 4 4 0 MerR, DNA binding F-box-like PF12937.7 EGE09437.1 - 6.3e-10 38.8 0.3 1.3e-09 37.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE09437.1 - 6e-09 35.6 0.7 1.2e-08 34.6 0.7 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGE09437.1 - 0.0093 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 F-box FTH PF01827.27 EGE09437.1 - 0.23 11.3 0.0 0.49 10.2 0.0 1.5 1 0 0 1 1 1 0 FTH domain HNH_2 PF13391.6 EGE09438.1 - 5.6e-12 45.6 0.0 9.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Mre11_DNA_bind PF04152.14 EGE09439.1 - 6.9e-53 179.4 0.7 1.4e-52 178.4 0.7 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGE09439.1 - 1.3e-13 51.9 1.1 6.1e-13 49.7 0.8 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGE09439.1 - 0.00068 19.9 0.0 0.01 16.0 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CHIP_TPR_N PF18391.1 EGE09439.1 - 3.3 8.6 7.9 0.2 12.4 1.2 2.3 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain ERCC4 PF02732.15 EGE09440.1 - 3.5e-21 76.0 2.0 6.5e-21 75.2 0.0 2.3 1 1 1 2 2 2 1 ERCC4 domain SspN PF08177.11 EGE09440.1 - 0.063 13.2 0.5 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Small acid-soluble spore protein N family MFS_1 PF07690.16 EGE09441.1 - 2.9e-17 62.6 20.7 2.9e-17 62.6 20.7 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EGE09441.1 - 0.0017 17.9 13.9 0.0066 16.0 0.9 3.5 4 0 0 4 4 4 2 Nodulin-like Pkinase_Tyr PF07714.17 EGE09445.1 - 3.6e-08 33.0 0.0 6.3e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGE09445.1 - 4.9e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGE09445.1 - 2.4e-06 27.7 1.3 7.1e-06 26.1 0.2 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGE09445.1 - 0.0012 18.3 0.0 0.0027 17.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGE09445.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EGE09445.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TMEM191C PF15194.6 EGE09446.1 - 0.027 14.7 0.1 1.3 9.3 0.0 2.0 2 0 0 2 2 2 0 TMEM191C family Aminotran_1_2 PF00155.21 EGE09449.1 - 3.2e-32 112.1 0.0 1.2e-30 106.9 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Syntaxin-18_N PF10496.9 EGE09451.1 - 3.3e-10 40.1 0.1 3.2e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EGE09451.1 - 3.4e-06 26.9 0.2 9.7e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 SNARE domain DUF1897 PF09005.10 EGE09451.1 - 5.4 6.6 5.9 20 4.8 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) TPR_1 PF00515.28 EGE09452.1 - 5.7e-14 51.2 6.9 3.1e-07 29.9 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGE09452.1 - 9.2e-14 50.4 5.6 1.5e-05 24.8 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGE09452.1 - 4.8e-10 39.6 0.1 1.2e-05 25.5 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 EGE09452.1 - 2.8e-07 30.4 0.1 5.5e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 EGE09452.1 - 8.9e-07 28.5 0.7 0.00026 20.8 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGE09452.1 - 2.1e-06 27.3 3.9 7.9e-05 22.3 0.8 3.6 2 1 1 3 3 3 1 TPR repeat TPR_8 PF13181.6 EGE09452.1 - 7.7e-06 25.7 6.3 0.0012 18.8 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGE09452.1 - 3.3e-05 24.2 0.2 8.3 7.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGE09452.1 - 9.3e-05 23.0 1.5 0.034 14.8 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGE09452.1 - 0.0012 18.9 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGE09452.1 - 0.006 16.9 0.2 0.36 11.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGE09452.1 - 0.065 14.1 3.7 0.28 12.1 0.1 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGE09452.1 - 0.48 10.4 4.3 1 9.3 0.0 3.4 5 0 0 5 5 3 0 Tetratricopeptide repeat HMA PF00403.26 EGE09453.1 - 2.7e-12 47.0 0.0 5.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EGE09453.1 - 6.8e-09 36.0 0.0 1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 EGE09454.1 - 3.1e-62 210.3 0.0 5.5e-62 209.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09454.1 - 5.2e-26 91.5 0.0 8.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGE09454.1 - 0.0057 16.0 0.0 0.0057 16.0 0.0 1.8 2 0 0 2 2 1 1 Kinase-like Haspin_kinase PF12330.8 EGE09454.1 - 0.033 13.1 0.7 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 EGE09454.1 - 0.034 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LCD1 PF09798.9 EGE09454.1 - 0.2 10.2 0.4 0.25 9.8 0.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein APH PF01636.23 EGE09454.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family MCM_bind PF09739.9 EGE09454.1 - 2.5 6.4 9.5 3.4 6.0 9.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 EGE09454.1 - 4.1 5.6 6.6 5.8 5.1 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.12 EGE09454.1 - 6.4 6.6 16.9 13 5.6 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Med3 PF11593.8 EGE09454.1 - 9.8 5.2 11.6 14 4.8 11.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RXT2_N PF08595.11 EGE09455.1 - 0.56 10.2 10.0 4.5 7.3 3.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal AMP-binding PF00501.28 EGE09456.1 - 5.3e-220 730.3 0.0 1.9e-76 257.4 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EGE09456.1 - 1.1e-122 410.0 0.0 2.1e-45 155.2 0.1 5.3 5 1 0 5 5 5 4 Condensation domain NAD_binding_4 PF07993.12 EGE09456.1 - 2.4e-33 115.4 0.0 6.5e-33 114.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGE09456.1 - 2.2e-25 88.8 0.7 9.3e-11 41.9 0.0 4.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 EGE09456.1 - 5.2e-09 35.9 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EGE09456.1 - 9.2e-06 26.5 0.0 0.36 11.8 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain AvrM_N PF18247.1 EGE09456.1 - 0.16 12.0 0.1 18 5.4 0.0 2.8 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain Usp PF00582.26 EGE09457.1 - 1.6e-22 80.5 0.1 3.4e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 Universal stress protein family Med27 PF11571.8 EGE09458.1 - 2.5e-20 72.6 2.0 2.8e-20 72.4 0.6 1.8 2 0 0 2 2 2 1 Mediator complex subunit 27 DUF4919 PF16266.5 EGE09458.1 - 0.099 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) SpoIIIAH PF12685.7 EGE09460.1 - 0.00032 20.6 1.5 0.00039 20.3 1.5 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein MFMR_assoc PF16596.5 EGE09460.1 - 0.0076 16.7 11.7 0.014 15.8 11.7 1.5 1 0 0 1 1 1 1 Disordered region downstream of MFMR GRA6 PF05084.13 EGE09460.1 - 0.06 13.3 2.1 0.12 12.3 2.1 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) AAR2 PF05282.11 EGE09460.1 - 0.085 12.3 0.5 0.12 11.8 0.5 1.1 1 0 0 1 1 1 0 AAR2 protein Presenilin PF01080.17 EGE09460.1 - 0.1 11.3 0.8 0.14 10.9 0.8 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EGE09460.1 - 0.18 10.6 2.1 0.25 10.1 2.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 EGE09460.1 - 0.27 9.7 4.1 0.29 9.6 4.1 1.1 1 0 0 1 1 1 0 Macoilin family TraV PF09676.10 EGE09460.1 - 0.53 11.3 5.4 1.5 9.8 3.8 2.0 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) SNF2_N PF00176.23 EGE09461.1 - 5.7e-67 225.9 0.0 9.6e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGE09461.1 - 3.3e-18 66.1 0.0 8e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGE09461.1 - 3.7e-05 23.8 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EGE09461.1 - 0.00077 19.6 0.1 0.0084 16.2 0.0 2.5 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain AAA_11 PF13086.6 EGE09461.1 - 1.3 8.8 0.0 1.3 8.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain Cluap1 PF10234.9 EGE09461.1 - 10 5.5 9.8 18 4.6 9.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Pkinase PF00069.25 EGE09463.1 - 4.1e-46 157.5 0.0 6.8e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09463.1 - 4e-23 82.0 0.0 6.8e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGE09463.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGE09463.1 - 0.0016 18.1 0.2 0.0052 16.4 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGE09463.1 - 0.37 10.4 2.4 0.22 11.1 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase SWIB PF02201.18 EGE09464.1 - 1.3e-22 79.5 0.0 2.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain RPN6_N PF18055.1 EGE09465.1 - 7.2e-30 103.7 1.8 2.1e-29 102.2 0.5 2.6 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGE09465.1 - 2.4e-20 73.0 1.5 1.2e-19 70.8 0.1 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EGE09465.1 - 1.4e-11 43.9 0.5 4e-11 42.4 0.5 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EGE09465.1 - 3.7e-06 27.1 13.8 0.0025 18.1 1.2 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGE09465.1 - 8.6e-06 25.4 4.5 2.6e-05 23.8 2.6 2.2 1 1 1 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 EGE09465.1 - 0.00024 20.8 0.2 0.00048 19.8 0.2 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_1 PF00515.28 EGE09465.1 - 0.00041 20.0 0.3 4.8 7.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGE09465.1 - 0.0018 18.1 2.1 5.9 7.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGE09465.1 - 0.0085 16.1 4.9 53 4.3 0.3 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGE09465.1 - 0.04 14.5 3.2 1.8 9.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EGE09465.1 - 0.057 13.4 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain NepR PF18557.1 EGE09465.1 - 0.16 11.6 0.9 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 Anti-sigma factor NepR TPR_14 PF13428.6 EGE09465.1 - 0.29 12.0 8.0 24 6.1 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGE09465.1 - 0.72 10.2 6.6 69 4.0 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGE09465.1 - 2.7 8.8 11.6 15 6.5 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Sof1 PF04158.14 EGE09466.1 - 2.4e-29 101.5 14.7 4.2e-29 100.6 14.7 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EGE09466.1 - 1.8e-27 95.0 6.0 1.3e-05 25.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE09466.1 - 3.1e-09 37.0 0.1 0.029 14.7 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGE09466.1 - 0.00068 18.7 0.0 0.048 12.6 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 EGE09467.1 - 2.9e-34 118.2 0.2 5.9e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGE09467.1 - 7.1e-28 97.7 0.1 1.6e-27 96.6 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGE09467.1 - 1.3e-05 25.2 0.6 4.1e-05 23.6 0.6 1.8 1 1 0 1 1 1 1 KR domain IF-2 PF11987.8 EGE09467.1 - 0.074 13.2 0.6 0.16 12.1 0.1 1.7 2 0 0 2 2 2 0 Translation-initiation factor 2 DUF2306 PF10067.9 EGE09468.1 - 1.1e-20 74.4 8.1 2.4e-20 73.3 8.1 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EGE09468.1 - 0.13 12.5 0.5 0.13 12.5 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF420) Fungal_trans_2 PF11951.8 EGE09469.1 - 1.8e-10 40.2 0.0 3.8e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE09469.1 - 7.8e-08 32.3 9.5 1.8e-07 31.2 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.19 EGE09470.1 - 1.4e-10 40.3 0.0 0.69 9.7 0.0 7.0 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat Imm47 PF15573.6 EGE09470.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 47 Pyridoxal_deC PF00282.19 EGE09471.1 - 4.4e-76 256.0 0.0 5.2e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGE09471.1 - 2.6e-08 33.2 0.0 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGE09471.1 - 1.8e-06 27.5 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 EGE09471.1 - 0.03 13.0 0.0 0.053 12.2 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS RINT1_TIP1 PF04437.13 EGE09472.1 - 4e-181 603.3 0.4 1e-180 601.9 0.0 1.8 2 1 0 2 2 2 1 RINT-1 / TIP-1 family SLX9 PF15341.6 EGE09472.1 - 0.019 15.4 3.5 0.045 14.1 3.5 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Uso1_p115_C PF04871.13 EGE09472.1 - 0.019 15.3 8.6 0.051 13.9 8.6 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nup54 PF13874.6 EGE09472.1 - 0.025 14.7 6.1 0.085 13.0 6.1 1.9 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4961 PF16328.5 EGE09472.1 - 0.043 13.1 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4961) RasGAP_C PF03836.15 EGE09472.1 - 0.33 11.1 4.4 0.31 11.2 2.6 1.8 2 0 0 2 2 2 0 RasGAP C-terminus ECH_1 PF00378.20 EGE09472.1 - 0.74 9.1 3.6 2.4 7.4 3.2 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase DNA_ligase_A_M PF01068.21 EGE09473.1 - 9.2e-51 172.4 0.0 5e-48 163.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EGE09473.1 - 9.8e-20 71.0 0.0 3.9e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_N PF04675.14 EGE09473.1 - 3.4e-16 60.0 0.3 6.8e-16 59.1 0.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EGE09473.1 - 0.02 15.2 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA ligase Peptidase_C36 PF05415.11 EGE09473.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase DJ-1_PfpI PF01965.24 EGE09474.1 - 3e-11 43.4 0.0 8.8e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGE09474.1 - 0.05 13.3 0.5 0.23 11.1 0.5 2.0 1 1 0 1 1 1 0 ThiJ/PfpI family-like GST_N_3 PF13417.6 EGE09475.1 - 2.8e-08 34.0 0.1 5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGE09475.1 - 2.3e-07 30.8 0.2 5.7e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGE09475.1 - 1.9e-06 28.1 0.0 3.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGE09475.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGE09475.1 - 0.0023 18.2 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGE09475.1 - 0.0024 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGE09475.1 - 0.097 13.4 0.0 0.16 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF3439 PF11921.8 EGE09476.1 - 0.39 10.7 6.1 1.3 9.0 6.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CTU2 PF10288.9 EGE09477.1 - 0.31 11.3 4.8 0.07 13.4 1.4 1.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Metallopep PF12044.8 EGE09478.1 - 7.6e-69 232.4 0.0 1.1e-42 146.1 0.0 2.1 1 1 1 2 2 2 2 Putative peptidase family Serglycin PF04360.12 EGE09478.1 - 0.73 9.8 7.8 1.7 8.6 7.8 1.6 1 0 0 1 1 1 0 Serglycin SdpI PF13630.6 EGE09481.1 - 2.9 8.1 9.3 6.1 7.0 7.9 1.9 2 0 0 2 2 2 0 SdpI/YhfL protein family CP2 PF04516.15 EGE09482.1 - 8.3e-78 260.8 0.1 1.2e-77 260.3 0.1 1.1 1 0 0 1 1 1 1 CP2 transcription factor HD PF01966.22 EGE09485.1 - 0.00054 20.2 0.1 0.001 19.3 0.1 1.5 1 0 0 1 1 1 1 HD domain Glyco_hydro_42M PF08532.10 EGE09486.1 - 0.032 13.7 0.1 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain Pribosyltran PF00156.27 EGE09487.1 - 3.1e-15 56.0 0.0 4.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGE09487.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 EGE09488.1 - 5.1e-114 381.7 0.0 6.8e-114 381.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol_B_exo2 PF10108.9 EGE09488.1 - 0.025 14.3 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB US6 PF17616.2 EGE09489.1 - 0.08 12.9 0.5 0.13 12.2 0.5 1.2 1 0 0 1 1 1 0 Viral unique short region 6 WD40 PF00400.32 EGE09490.1 - 3.1e-36 122.8 10.7 1.8e-05 25.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGE09490.1 - 7.6e-10 39.0 0.1 0.019 15.3 0.0 4.3 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGE09490.1 - 0.055 12.2 0.9 1.9 7.1 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EGE09490.1 - 0.12 11.0 0.5 2.6 6.6 0.2 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TRAPP PF04051.16 EGE09491.1 - 3.6e-35 120.8 0.0 4.4e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EGE09491.1 - 0.0026 16.7 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 EGE09493.1 - 3.4e-05 23.7 0.1 5.4e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 LisH HD PF01966.22 EGE09496.1 - 0.00018 21.7 0.0 0.00034 20.8 0.0 1.5 1 1 0 1 1 1 1 HD domain DIOX_N PF14226.6 EGE09497.1 - 1.8e-22 80.3 0.0 2.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGE09497.1 - 4.3e-19 68.9 0.0 9.2e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF723 PF05265.13 EGE09497.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) zinc_ribbon_15 PF17032.5 EGE09498.1 - 0.0026 18.5 1.2 0.0039 17.9 1.2 1.2 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EGE09498.1 - 0.077 12.6 0.9 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 RecR protein zf-LITAF-like PF10601.9 EGE09498.1 - 1.9 8.8 8.7 7.3 6.9 0.4 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain Dynein_light PF01221.18 EGE09499.1 - 1.3e-37 127.9 1.8 1.6e-37 127.7 1.8 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF1805 PF08827.11 EGE09499.1 - 0.16 12.3 0.5 0.23 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RRM_1 PF00076.22 EGE09500.1 - 3.2e-71 235.1 0.7 3.7e-15 55.5 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGE09500.1 - 7.6e-07 29.0 0.4 0.0047 16.9 0.0 4.9 5 1 0 5 5 5 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EGE09500.1 - 1.2e-06 28.5 0.1 7.5 6.7 0.0 5.8 6 0 0 6 6 6 3 Limkain b1 RRM_7 PF16367.5 EGE09500.1 - 2e-06 27.8 0.0 0.31 11.2 0.0 4.5 4 1 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 EGE09500.1 - 2.3e-05 24.2 0.2 0.16 11.9 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGE09500.1 - 5.9e-05 22.7 0.0 0.017 14.8 0.0 3.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rota_NS53 PF00981.17 EGE09500.1 - 0.21 10.4 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Aldo_ket_red PF00248.21 EGE09501.1 - 3.1e-44 151.3 0.0 4e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EGE09502.1 - 0.0056 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GHMP_kinases_C PF08544.13 EGE09502.1 - 0.029 14.8 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal UPF1_Zn_bind PF09416.10 EGE09502.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Pkinase PF00069.25 EGE09504.1 - 3.3e-05 23.4 0.0 3.7e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain NIF PF03031.18 EGE09505.1 - 1.1e-54 184.4 0.5 1.6e-54 183.9 0.5 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DNase_NucA_NucB PF14040.6 EGE09505.1 - 0.014 15.8 0.2 0.014 15.8 0.2 2.0 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB DUF4658 PF15555.6 EGE09505.1 - 0.098 12.8 1.4 0.19 11.8 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) LRR_4 PF12799.7 EGE09506.1 - 7e-36 121.7 72.3 2.7e-08 34.0 5.2 6.5 1 1 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGE09506.1 - 4.2e-21 74.5 37.5 6.1e-06 25.9 5.8 6.1 3 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EGE09506.1 - 1.4e-14 54.0 19.5 3e-07 30.1 3.8 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EGE09506.1 - 0.00044 20.1 26.1 0.17 12.0 0.2 7.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 EGE09506.1 - 0.001 19.3 31.1 2.9 8.8 0.9 8.9 10 0 0 10 10 10 3 Leucine Rich Repeat ABC_membrane_2 PF06472.15 EGE09507.1 - 5.5e-86 288.3 0.5 8.8e-86 287.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGE09507.1 - 4.1e-08 33.8 0.0 8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ALIX_LYPXL_bnd PF13949.6 EGE09507.1 - 0.084 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Clr2 PF10383.9 EGE09508.1 - 9.5e-23 81.6 0.0 1.7e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 EGE09508.1 - 4.8e-17 62.5 0.7 1.3e-16 61.1 0.7 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 2OG-FeII_Oxy PF03171.20 EGE09509.1 - 0.00028 21.3 0.0 0.0008 19.8 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAST_1 PF06743.15 EGE09510.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 ApoM PF11032.8 EGE09510.1 - 0.14 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 ApoM domain CLTH PF10607.9 EGE09511.1 - 2.5e-29 102.1 0.0 3.5e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGE09511.1 - 4.2e-08 33.1 0.7 8.1e-08 32.2 0.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EGE09511.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EGE09511.1 - 0.00077 19.4 0.5 0.0014 18.6 0.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGE09511.1 - 0.0012 19.1 0.9 0.0022 18.3 0.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGE09511.1 - 0.013 15.4 0.7 0.024 14.5 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGE09511.1 - 0.014 15.3 0.9 0.027 14.3 0.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGE09511.1 - 0.025 14.4 1.9 0.048 13.5 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGE09511.1 - 0.03 14.2 1.2 0.057 13.3 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ZapD PF07072.11 EGE09513.1 - 0.003 17.3 2.9 0.0041 16.9 2.9 1.2 1 0 0 1 1 1 1 Cell division protein DFP PF04127.15 EGE09513.1 - 0.064 13.1 0.2 0.095 12.5 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein KR PF08659.10 EGE09513.1 - 0.23 11.3 0.0 4.5 7.1 0.0 2.0 1 1 1 2 2 2 0 KR domain Phage_min_cap2 PF06152.11 EGE09514.1 - 0.064 12.2 6.0 0.073 12.0 6.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Bap31_Bap29_C PF18035.1 EGE09514.1 - 0.18 11.9 3.7 0.4 10.7 3.7 1.7 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain MPS2 PF17060.5 EGE09514.1 - 0.41 9.8 3.7 0.44 9.8 3.7 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4404 PF14357.6 EGE09514.1 - 0.51 11.0 6.6 0.17 12.5 3.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF5320 PF17253.2 EGE09514.1 - 0.85 10.7 4.5 3.5 8.8 0.3 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) AAA_23 PF13476.6 EGE09514.1 - 5 7.6 9.0 5.8 7.4 9.0 1.1 1 0 0 1 1 1 0 AAA domain Nse5 PF08691.10 EGE09515.1 - 0.087 11.5 6.9 0.094 11.4 6.9 1.1 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 PPDK_N PF01326.19 EGE09515.1 - 0.16 11.2 3.7 0.071 12.4 0.3 1.7 1 1 1 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain FmdA_AmdA PF03069.15 EGE09516.1 - 1e-57 195.7 0.0 2.3e-34 118.9 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family AA_permease_2 PF13520.6 EGE09517.1 - 2e-55 188.3 43.9 2.6e-55 188.0 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGE09517.1 - 2.5e-20 72.5 41.3 3.3e-20 72.1 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3043 PF11241.8 EGE09517.1 - 3.8 7.5 6.6 9.6 6.2 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Ost5 PF05251.12 EGE09521.1 - 0.01 16.1 1.6 0.01 16.1 1.6 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 COQ9 PF08511.11 EGE09522.1 - 1.4e-25 88.8 0.5 3.3e-25 87.7 0.1 1.8 2 0 0 2 2 2 1 COQ9 UvrA_inter PF17760.1 EGE09523.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 UvrA interaction domain WD40 PF00400.32 EGE09524.1 - 2.9e-08 34.3 0.2 1 10.3 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DNA_methylase PF00145.17 EGE09525.1 - 1.7e-32 113.1 0.0 3.3e-32 112.2 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EGE09525.1 - 1.3e-05 25.1 0.1 0.052 13.4 0.1 2.7 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 EGE09525.1 - 0.034 14.2 0.1 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain RasGAP PF00616.19 EGE09526.1 - 1.7e-24 86.7 0.0 1.2e-21 77.4 0.0 2.7 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGE09526.1 - 5e-07 30.0 0.0 1.7e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 C2 domain MKT1_C PF12246.8 EGE09527.1 - 3.9e-85 284.9 0.0 4.7e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication UPF0449 PF15136.6 EGE09527.1 - 0.076 13.5 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Phe_hydrox_dim PF07976.12 EGE09527.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Phenol hydroxylase, C-terminal dimerisation domain UQ_con PF00179.26 EGE09528.1 - 5.8e-25 87.6 0.0 6.6e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGE09528.1 - 7.4e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGE09528.1 - 0.017 15.4 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Complex1_49kDa PF00346.19 EGE09529.1 - 4.2e-123 409.8 0.0 6e-123 409.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EGE09529.1 - 0.007 15.3 0.0 0.012 14.6 0.0 1.3 1 1 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 EGE09530.1 - 3.1e-27 95.2 0.0 5.6e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGE09530.1 - 5.9e-19 67.3 0.0 8.1e-19 66.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 EGE09531.1 - 2.6e-63 213.6 0.0 5.7e-63 212.5 0.0 1.4 1 1 1 2 2 2 1 ThiF family E2_bind PF08825.10 EGE09531.1 - 8.4e-30 102.8 0.4 1.4e-29 102.1 0.4 1.4 1 0 0 1 1 1 1 E2 binding domain E1_UFD PF09358.10 EGE09531.1 - 0.0061 17.2 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain Ecm33 PF12454.8 EGE09531.1 - 0.033 14.3 2.0 0.069 13.3 2.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein SNCAIP_SNCA_bd PF16700.5 EGE09531.1 - 0.13 12.0 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain UBA_e1_thiolCys PF10585.9 EGE09531.1 - 0.35 10.8 3.6 5.7 6.8 0.1 2.6 2 1 0 2 2 2 0 Ubiquitin-activating enzyme active site Rad50_zn_hook PF04423.14 EGE09531.1 - 4.5 7.2 5.4 13 5.8 0.4 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Telomere_reg-2 PF10193.9 EGE09532.1 - 1.3e-23 83.5 0.0 4.3e-23 81.8 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein Fungal_trans PF04082.18 EGE09533.1 - 1e-22 80.4 0.1 1.7e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EGE09533.1 - 3.3e-08 33.5 11.6 6.5e-08 32.6 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 EGE09534.1 - 2.1e-36 125.9 7.0 9.5e-23 80.9 1.4 2.9 1 1 1 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EGE09534.1 - 1.1e-08 34.9 1.0 1.7e-08 34.2 1.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EGE09534.1 - 1.5e-08 34.7 5.9 2.8e-05 23.9 0.2 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EGE09534.1 - 5.1e-07 28.7 2.2 0.00055 18.7 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 EGE09534.1 - 1.3e-06 27.8 0.1 9.2e-06 25.1 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGE09534.1 - 0.00047 19.5 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EGE09534.1 - 0.001 18.4 0.1 0.034 13.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGE09534.1 - 0.0017 18.5 0.2 0.0064 16.7 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGE09534.1 - 0.0019 17.3 0.3 0.0019 17.3 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EGE09534.1 - 0.003 16.9 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGE09534.1 - 0.058 12.4 0.4 0.11 11.5 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EGE09534.1 - 0.087 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GST_C_2 PF13410.6 EGE09538.1 - 0.15 12.1 0.1 0.8 9.8 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-MYND PF01753.18 EGE09539.1 - 1.7e-08 34.4 11.9 2.4e-08 33.9 9.0 2.4 2 0 0 2 2 2 1 MYND finger SPOB_a PF14689.6 EGE09539.1 - 0.18 11.5 0.3 0.31 10.8 0.3 1.3 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain Cation_efflux PF01545.21 EGE09541.1 - 1.3e-30 106.6 8.0 3.1e-30 105.4 8.0 1.6 1 1 0 1 1 1 1 Cation efflux family MARVEL PF01284.23 EGE09541.1 - 0.00016 21.7 0.1 0.099 12.7 0.0 2.5 1 1 1 2 2 2 2 Membrane-associating domain EphA2_TM PF14575.6 EGE09541.1 - 0.19 12.6 1.6 8.3 7.4 0.0 3.1 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain MAGI_u5 PF16666.5 EGE09543.1 - 1.1 9.4 6.2 0.11 12.7 1.5 1.7 2 0 0 2 2 2 0 Unstructured region on MAGI Ribosomal_S13 PF00416.22 EGE09545.1 - 5.1e-37 127.1 1.2 6e-37 126.9 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 EGE09545.1 - 0.14 12.6 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Peptidase_S10 PF00450.22 EGE09546.1 - 7.6e-29 101.3 0.0 8.4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SBDS_C PF09377.10 EGE09547.1 - 8.3e-43 145.1 0.0 1.3e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EGE09547.1 - 7.2e-33 112.5 0.1 1.7e-32 111.4 0.1 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SUIM_assoc PF16619.5 EGE09547.1 - 0.0029 17.6 4.1 0.0068 16.5 4.1 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 EGE09547.1 - 0.033 12.9 1.7 0.051 12.4 1.7 1.2 1 0 0 1 1 1 0 Presenilin NST1 PF13945.6 EGE09547.1 - 0.09 12.9 16.0 2.8 8.0 1.2 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator DUF4834 PF16118.5 EGE09547.1 - 0.1 13.6 5.0 0.1 13.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) FYDLN_acid PF09538.10 EGE09547.1 - 0.12 13.0 5.6 5.2 7.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) POX PF07526.11 EGE09547.1 - 0.2 12.2 4.3 3.5 8.2 0.2 2.3 2 0 0 2 2 2 0 Associated with HOX DUF4820 PF16091.5 EGE09547.1 - 0.32 10.3 7.6 0.8 9.0 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 EGE09547.1 - 0.65 9.7 7.8 7.1 6.3 0.5 3.0 3 0 0 3 3 3 0 FAM176 family RPN2_C PF18004.1 EGE09547.1 - 2.6 8.0 9.5 8.7 6.2 1.8 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Coilin_N PF15862.5 EGE09547.1 - 4.3 7.1 11.1 2.5 7.9 0.5 2.2 2 0 0 2 2 2 0 Coilin N-terminus Roughex PF06020.11 EGE09547.1 - 6 5.9 9.0 0.17 11.0 2.5 1.6 2 0 0 2 2 2 0 Drosophila roughex protein Rsm1 PF08600.10 EGE09548.1 - 1.1 9.5 5.2 2.9 8.1 5.2 1.7 1 0 0 1 1 1 0 Rsm1-like HTH_46 PF15977.5 EGE09550.1 - 0.015 15.3 0.3 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Peptidase_S8 PF00082.22 EGE09552.1 - 1.7e-33 116.2 7.4 4e-33 115.0 7.4 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EGE09552.1 - 2.5e-10 40.9 0.0 1.1e-09 38.9 0.0 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 Ras PF00071.22 EGE09553.1 - 1.5e-37 128.7 0.0 1.7e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGE09553.1 - 4.2e-13 49.6 0.0 7.2e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGE09553.1 - 0.003 17.0 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.22 EGE09554.1 - 2.2e-12 46.6 0.0 5.8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.6 EGE09555.1 - 1.1e-72 244.5 1.7 2e-72 243.5 1.7 1.4 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EGE09555.1 - 0.00015 21.6 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T_C PF15511.6 EGE09556.1 - 1.3e-36 124.9 0.0 6.9e-36 122.7 0.0 2.0 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGE09556.1 - 5.5e-08 33.1 0.1 1.1e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EGE09556.1 - 8.7e-05 22.9 0.2 0.00024 21.5 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGE09556.1 - 0.0012 19.0 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bombolitin PF08096.11 EGE09556.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Bombolitin family CENP-X PF09415.10 EGE09556.1 - 0.22 11.8 0.4 0.6 10.5 0.0 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X SURF1 PF02104.15 EGE09557.1 - 2.6e-47 161.3 0.0 3.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 EGE09558.1 - 3e-10 40.2 0.0 6.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF3287 PF11690.8 EGE09558.1 - 0.13 12.0 1.8 0.26 11.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) DUF737 PF05300.11 EGE09558.1 - 0.47 10.8 15.4 1.1 9.6 15.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CDC45 PF02724.14 EGE09558.1 - 7.3 4.8 11.6 14 3.8 11.6 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.9 EGE09559.1 - 1.1e-08 35.5 12.5 1.3e-08 35.2 12.5 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EGE09559.1 - 1.5e-05 25.0 2.5 2.3e-05 24.4 2.5 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EGE09559.1 - 0.072 13.1 0.3 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YppG PF14179.6 EGE09559.1 - 0.14 12.9 4.2 0.24 12.1 2.7 1.9 2 0 0 2 2 2 0 YppG-like protein Bindin PF02084.15 EGE09559.1 - 0.22 11.8 3.9 0.29 11.4 3.9 1.2 1 0 0 1 1 1 0 Bindin DUF3275 PF11679.8 EGE09559.1 - 1.8 8.5 6.0 1.6 8.7 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Sas10_Utp3 PF04000.15 EGE09560.1 - 3.2e-18 66.1 0.9 3.2e-18 66.1 0.9 2.4 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Roughex PF06020.11 EGE09560.1 - 1.1 8.3 9.1 1.7 7.6 9.1 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EGE09560.1 - 9.5 4.4 18.3 12 4.0 18.3 1.2 1 0 0 1 1 1 0 CDC45-like protein ApbA_C PF08546.11 EGE09561.1 - 1.6e-31 109.1 0.1 2.5e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGE09561.1 - 6.1e-25 87.6 0.0 1.4e-23 83.2 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.13 EGE09562.1 - 1.6e-96 321.9 0.0 1.9e-96 321.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EGE09563.1 - 1.7e-39 134.6 12.1 1.9e-39 134.4 12.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Sec2p PF06428.11 EGE09564.1 - 7e-29 99.6 10.4 7e-29 99.6 10.4 2.5 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p OmpH PF03938.14 EGE09564.1 - 0.14 12.5 11.1 0.28 11.5 11.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 EGE09564.1 - 0.37 8.3 15.5 0.53 7.7 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3987 PF13148.6 EGE09564.1 - 0.63 9.0 9.7 0.11 11.4 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Spc7 PF08317.11 EGE09564.1 - 1.1 8.1 12.1 1.9 7.3 12.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.6 EGE09564.1 - 2.5 8.2 11.7 14 5.8 11.5 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 GCN5L1 PF06320.13 EGE09564.1 - 2.6 8.2 10.1 1.3 9.1 6.8 2.2 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF5383 PF17355.2 EGE09564.1 - 6.5 7.1 10.2 72 3.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) PRP21_like_P PF12230.8 EGE09565.1 - 6.8e-56 189.6 7.6 1.9e-30 106.4 2.1 2.2 2 0 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGE09565.1 - 1.5e-36 124.1 3.0 9.1e-18 64.0 0.1 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EGE09565.1 - 0.023 14.3 0.6 0.057 13.0 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 EGE09565.1 - 0.24 11.5 1.5 0.84 9.8 1.5 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Toprim_Crpt PF13342.6 EGE09565.1 - 0.64 10.0 1.9 7.3 6.6 0.5 2.4 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase PMT PF02366.18 EGE09566.1 - 3.4e-32 112.0 0.1 4.1e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SDP_N PF12278.8 EGE09566.1 - 1.8 8.7 4.3 2.4 8.3 4.3 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Peptidase_S32 PF05579.13 EGE09568.1 - 0.00096 18.4 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.6 EGE09568.1 - 0.073 14.0 0.0 0.1 13.5 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain F-box-like PF12937.7 EGE09569.1 - 8.7e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGE09569.1 - 0.00022 21.0 0.6 0.00053 19.8 0.3 1.8 2 0 0 2 2 2 1 F-box domain PRANC PF09372.10 EGE09569.1 - 0.026 14.9 0.2 0.056 13.8 0.2 1.5 1 0 0 1 1 1 0 PRANC domain TB2_DP1_HVA22 PF03134.19 EGE09570.1 - 3e-23 81.5 9.1 4.6e-23 81.0 9.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MIF4G PF02854.19 EGE09572.1 - 7e-53 179.4 0.0 1.1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EGE09572.1 - 1.7e-25 89.0 2.3 4.5e-25 87.6 2.3 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Methyltransf_16 PF10294.9 EGE09573.1 - 3e-09 36.8 0.1 0.00017 21.4 0.0 2.4 2 1 0 2 2 2 2 Lysine methyltransferase LVIVD PF08309.11 EGE09574.1 - 7e-05 22.1 0.4 0.15 11.4 0.0 4.0 4 0 0 4 4 4 1 LVIVD repeat Beta_propel PF09826.9 EGE09574.1 - 0.018 13.9 0.2 0.3 9.9 0.1 2.3 1 1 1 2 2 2 0 Beta propeller domain c-SKI_SMAD_bind PF08782.10 EGE09574.1 - 0.088 13.1 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DUF523 PF04463.12 EGE09575.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF523) AMP-binding PF00501.28 EGE09576.1 - 7.8e-44 149.9 0.0 9.2e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 EGE09577.1 - 5.1e-34 117.8 22.3 6.7e-34 117.3 22.3 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE09577.1 - 1.3e-15 57.2 10.2 1.7e-15 56.8 10.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EGE09577.1 - 2.9e-13 49.1 10.0 3.6e-13 48.8 10.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EGE09577.1 - 0.17 10.2 6.5 0.2 9.9 5.9 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sin3a_C PF16879.5 EGE09580.1 - 1.3e-77 261.4 0.1 1.3e-77 261.4 0.1 3.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EGE09580.1 - 3.1e-43 145.7 1.1 9.2e-18 64.1 0.0 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EGE09580.1 - 3.1e-40 136.2 0.0 9.1e-40 134.7 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor TMEM247 PF15444.6 EGE09580.1 - 8.9 6.3 11.7 32 4.5 11.7 1.9 1 0 0 1 1 1 0 Transmembrane protein 247 Peptidase_S64 PF08192.11 EGE09580.1 - 9 4.6 9.7 10 4.5 0.5 2.2 2 0 0 2 2 2 0 Peptidase family S64 FAD_binding_2 PF00890.24 EGE09581.1 - 9.7e-82 275.3 0.4 1.3e-81 274.8 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EGE09581.1 - 4.1e-21 74.9 0.0 7.1e-20 70.9 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EGE09581.1 - 5.2e-12 46.0 0.5 1.5e-11 44.5 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGE09581.1 - 3.8e-10 39.7 1.2 1.5e-09 37.8 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGE09581.1 - 2.4e-08 34.1 1.2 8.6e-08 32.3 0.2 2.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGE09581.1 - 1.2e-07 31.3 0.3 1.2e-06 28.0 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGE09581.1 - 1.3e-06 27.9 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGE09581.1 - 2.1e-05 23.4 4.8 0.00015 20.6 1.0 2.9 2 1 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EGE09581.1 - 0.00012 21.3 1.6 0.029 13.5 0.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGE09581.1 - 0.00064 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGE09581.1 - 0.00066 19.0 0.3 0.082 12.1 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EGE09581.1 - 0.036 14.6 1.4 6.7 7.4 0.1 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 EGE09583.1 - 2.6e-12 47.0 7.6 0.11 13.4 0.2 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat MFS_1 PF07690.16 EGE09584.1 - 7.9e-18 64.5 14.0 8.9e-18 64.3 14.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGE09584.1 - 4.2e-06 25.9 5.3 8.6e-06 24.9 5.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Suc_Fer-like PF06999.12 EGE09588.1 - 3.1e-69 232.8 0.0 3.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SNARE PF05739.19 EGE09589.1 - 0.21 11.6 6.3 0.37 10.8 6.3 1.3 1 0 0 1 1 1 0 SNARE domain Prominin PF05478.11 EGE09589.1 - 8.3 4.2 9.0 11 3.8 9.0 1.0 1 0 0 1 1 1 0 Prominin PHP_C PF13263.6 EGE09591.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 PHP-associated HNH_2 PF13391.6 EGE09592.1 - 1.7e-08 34.5 0.0 1.4e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease BRF1 PF07741.13 EGE09592.1 - 1.9 8.9 5.7 0.26 11.6 1.2 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Phosphodiest PF01663.22 EGE09593.1 - 6.7e-89 299.0 0.1 8.7e-89 298.6 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGE09593.1 - 0.00049 19.6 0.0 0.22 10.9 0.0 2.3 1 1 0 2 2 2 2 Sulfatase Metalloenzyme PF01676.18 EGE09593.1 - 0.00099 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 EGE09593.1 - 0.076 13.1 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 PglZ domain Ham1p_like PF01725.16 EGE09594.1 - 0.0008 19.4 0.1 0.011 15.7 0.2 1.9 1 1 0 1 1 1 1 Ham1 family 3-dmu-9_3-mt PF06983.13 EGE09595.1 - 4.6e-39 133.6 0.0 6.3e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.10 EGE09595.1 - 0.0097 15.6 0.1 0.021 14.5 0.1 1.6 1 0 0 1 1 1 1 Doublesex dimerisation domain Kinesin PF00225.23 EGE09596.1 - 2.1e-53 181.4 0.0 3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGE09596.1 - 6.6e-25 87.8 0.0 2e-24 86.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 EGE09596.1 - 3.7e-08 33.7 0.2 1.4e-07 31.8 0.2 2.1 1 0 0 1 1 1 1 Kinesin protein 1B AAA_22 PF13401.6 EGE09596.1 - 0.1 12.9 0.1 0.4 10.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.25 EGE09597.1 - 1.9e-15 57.0 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGE09597.1 - 5.6e-09 35.7 0.0 7.6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGE09597.1 - 0.00018 20.4 0.2 0.00027 19.8 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGE09597.1 - 0.00024 21.1 0.2 0.00048 20.1 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGE09597.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EGE09597.1 - 0.053 12.8 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase FTR PF01913.18 EGE09597.1 - 0.083 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Neil1-DNA_bind PF09292.10 EGE09598.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.6 4 1 1 5 5 5 0 Endonuclease VIII-like 1, DNA bind GFA PF04828.14 EGE09599.1 - 2.1e-07 31.2 0.2 3.6e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.13 EGE09600.1 - 0.00015 21.8 0.4 0.00024 21.2 0.4 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 EGE09600.1 - 0.0072 16.7 1.7 0.36 11.2 0.1 2.2 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EGE09600.1 - 0.02 15.2 1.7 0.03 14.6 0.7 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NPR3 PF03666.13 EGE09601.1 - 6.5e-129 430.7 0.2 5e-78 263.0 0.0 3.1 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Mago-bind PF09282.10 EGE09601.1 - 0.26 11.2 3.8 0.94 9.4 3.8 2.0 1 0 0 1 1 1 0 Mago binding Hepatitis_core PF00906.20 EGE09601.1 - 1.7 8.1 4.8 4.7 6.7 4.2 2.0 2 0 0 2 2 2 0 Hepatitis core antigen Presenilin PF01080.17 EGE09601.1 - 5.7 5.6 7.5 1.1 8.0 2.7 1.9 2 0 0 2 2 2 0 Presenilin Ank_5 PF13857.6 EGE09603.1 - 1.5e-12 47.5 0.4 1.3e-10 41.4 0.2 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGE09603.1 - 1.2e-10 41.7 0.0 1.8e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGE09603.1 - 1.2e-08 35.4 0.3 2.8e-08 34.3 0.2 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGE09603.1 - 9.4e-07 28.7 0.1 3.7e-05 23.8 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGE09603.1 - 0.00054 20.3 0.0 0.011 16.1 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.6 EGE09603.1 - 0.08 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein LRR19-TM PF15176.6 EGE09604.1 - 0.017 15.1 0.2 0.04 13.9 0.2 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Chitin_synth_2 PF03142.15 EGE09605.1 - 5.9e-291 965.6 0.1 7e-291 965.4 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EGE09605.1 - 7.7e-13 48.8 4.3 2.1e-12 47.3 4.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EGE09605.1 - 9.8e-10 38.7 0.0 3.3e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGE09605.1 - 4.2e-05 23.1 0.1 0.00091 18.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EGE09605.1 - 0.0029 17.4 0.0 0.043 13.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sel1 PF08238.12 EGE09606.1 - 1.7e-18 66.7 4.7 2.3e-06 28.1 0.1 3.4 3 0 0 3 3 3 3 Sel1 repeat MFS_1 PF07690.16 EGE09607.1 - 4.2e-09 35.8 23.7 4.4e-08 32.5 22.8 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EGE09609.1 - 3.7e-57 194.1 0.0 6.1e-56 190.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATP-synt_C PF00137.21 EGE09611.1 - 2.4e-36 123.9 34.2 5.1e-22 78.0 15.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1713 PF08213.11 EGE09612.1 - 1.2e-10 41.1 22.0 1.2e-10 41.1 22.0 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EGE09612.1 - 0.009 16.7 0.5 0.025 15.3 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Vps36_ESCRT-II PF11605.8 EGE09614.1 - 4.3e-22 78.1 0.0 5.7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EGE09614.1 - 3.5e-20 71.2 1.3 3.5e-20 71.2 1.3 1.6 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EGE09614.1 - 1.9e-05 24.6 0.5 0.00043 20.3 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 EGE09614.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 GRAM domain zf-MIZ PF02891.20 EGE09614.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger LON_substr_bdg PF02190.16 EGE09616.1 - 2.1e-36 125.8 0.4 3.7e-36 124.9 0.1 1.5 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ketoacyl-synt PF00109.26 EGE09617.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Collagen PF01391.18 EGE09620.1 - 0.029 14.1 8.0 0.058 13.2 8.0 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_equinum_CBS_127.97-ASM15117v1/GCA_000151175.1_ASM15117v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_equinum_CBS_127.97-ASM15117v1/GCA_000151175.1_ASM15117v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_equinum_CBS_127.97-ASM15117v1/GCA_000151175.1_ASM15117v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Trichophyton_equinum_CBS_127.97-ASM15117v1/GCA_000151175.1_ASM15117v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:37:26 2019 # [ok]