# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pkinase PF00069.25 KND85066.1 - 0.0083 15.5 0.0 0.0099 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Transketolase_C PF02780.20 KND85066.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Transketolase, C-terminal domain HNH_2 PF13391.6 KND85078.1 - 9e-16 57.8 0.0 1.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.25 KND85219.1 - 6.8e-16 58.4 0.0 2.7e-15 56.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND85219.1 - 1.1e-10 41.3 0.0 2.5e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KND85219.1 - 0.00056 19.3 0.0 0.00078 18.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND85299.1 - 0.00013 22.0 1.6 0.00036 20.5 1.6 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF664 PF04978.12 KND85539.1 - 0.081 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF664) NACHT PF05729.12 KND85546.1 - 1.5e-11 44.5 0.4 8.6e-11 42.0 0.4 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND85546.1 - 1.5e-07 31.9 0.1 2.1e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KND85546.1 - 0.0014 17.9 0.0 0.014 14.6 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KND85546.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KND85546.1 - 0.069 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 KND85565.1 - 3.8e-05 22.8 36.7 0.0016 17.4 36.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 KND85605.1 - 8.6e-18 64.6 0.0 1.1e-16 61.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND85605.1 - 0.0018 17.6 0.0 0.0041 16.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3435 PF11917.8 KND85610.1 - 7.1e-93 311.8 0.0 1.6e-92 310.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Pkinase PF00069.25 KND85730.1 - 4.6e-08 32.8 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND85730.1 - 0.00027 20.9 0.0 0.00035 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 KND85730.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.14 KND85730.1 - 0.085 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KND85730.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.16 KND85793.1 - 9.5e-12 44.5 20.2 9.5e-12 44.5 20.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KND85793.1 - 3.1 6.0 5.5 3.8 5.7 5.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) NAD_binding_6 PF08030.12 KND85816.1 - 1.1e-08 35.4 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DEAD PF00270.29 KND85829.1 - 2.1e-35 122.1 0.0 3.9e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND85829.1 - 5.4e-24 84.7 0.1 3.3e-22 78.9 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND85829.1 - 1.3e-07 31.8 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 KND85829.1 - 0.0072 16.9 0.6 0.019 15.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) DDE_1 PF03184.19 KND85843.1 - 9.4e-08 31.9 0.0 2.1e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF2011 PF09428.10 KND85843.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Arc PF03869.14 KND85912.1 - 0.017 15.0 0.1 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 Arc-like DNA binding domain STAT6_C PF14596.6 KND85912.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 STAT6 C-terminal Methyltr_RsmB-F PF01189.17 KND85973.1 - 3.2e-17 62.9 0.0 3.3e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F TMV_coat PF00721.21 KND85973.1 - 0.07 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Virus coat protein (TMV like) Mito_carr PF00153.27 KND85974.1 - 2e-50 168.7 2.2 2.8e-21 75.2 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.9 KND85978.1 - 6.7e-88 294.1 0.1 2.4e-87 292.3 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) PCMT PF01135.19 KND86008.1 - 4.9e-49 166.9 0.0 6.8e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KND86008.1 - 0.00028 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KND86008.1 - 0.016 15.2 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KND86008.1 - 0.025 15.3 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UCH PF00443.29 KND86081.1 - 3.1e-47 161.3 0.1 7.7e-47 159.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND86081.1 - 1.2e-23 84.2 0.1 7.9e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4407 PF14362.6 KND86081.1 - 0.59 9.4 11.5 0.97 8.7 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRP-alpha_N PF04086.13 KND86081.1 - 2 8.3 40.2 0.62 9.9 31.6 3.2 2 1 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.11 KND86081.1 - 2.2 6.7 23.2 4.8 5.6 23.2 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein Polyketide_cyc PF03364.20 KND86105.1 - 6e-19 68.5 0.0 7.6e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF45 PF01863.17 KND86106.1 - 0.28 11.2 5.7 0.38 10.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Neur_chan_memb PF02932.16 KND86106.1 - 1.4 8.9 2.9 2 8.4 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.13 KND86106.1 - 4.1 6.9 15.0 4.9 6.7 15.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1993 PF09351.10 KND86106.1 - 5.1 7.2 9.3 7.1 6.7 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) SAPS PF04499.15 KND86106.1 - 6 5.5 8.1 7.2 5.3 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein APH PF01636.23 KND86108.1 - 1.2e-09 38.4 0.4 1.3e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86108.1 - 4.1e-05 23.3 0.0 6.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DNA_pol_A_exo1 PF01612.20 KND86109.1 - 8.3e-07 28.9 0.0 9.2e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DJ-1_PfpI PF01965.24 KND86111.1 - 6.8e-13 48.7 0.0 9.5e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4575 PF15143.6 KND86111.1 - 0.016 15.4 0.6 0.039 14.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4575) SLAC1 PF03595.17 KND86112.1 - 4.2e-20 72.3 4.4 5.1e-20 72.0 4.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF1180 PF06679.12 KND86113.1 - 0.00057 20.3 2.3 0.0011 19.5 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF2332 PF10094.9 KND86113.1 - 0.068 12.6 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) RAP1 PF07218.11 KND86113.1 - 1.5 7.0 8.9 1.9 6.7 8.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 KND86114.1 - 2.4e-21 76.3 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86114.1 - 2.3e-17 63.1 0.0 3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND86114.1 - 5e-05 22.8 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND86114.1 - 9.4e-05 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND86114.1 - 0.0097 15.8 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86114.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KND86114.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KND86114.1 - 0.19 10.7 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3328 PF11807.8 KND86115.1 - 6.5e-51 173.2 1.2 8.3e-51 172.9 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APH PF01636.23 KND86116.1 - 0.00079 19.4 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86116.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KND86117.1 - 9.7e-10 38.2 0.0 3.5e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86117.1 - 3.9e-07 29.6 0.0 6.6e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND86117.1 - 0.0038 17.2 0.8 0.059 13.3 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND86117.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KND86117.1 - 0.059 12.9 0.0 1.2 8.7 0.0 2.3 1 1 0 2 2 2 0 Choline/ethanolamine kinase DOG1 PF14144.6 KND86117.1 - 0.18 12.0 0.1 8.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Seed dormancy control Fer2_3 PF13085.6 KND86119.1 - 1e-31 109.1 0.0 1.3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 KND86119.1 - 0.00082 19.3 0.2 0.0015 18.5 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Receptor_2B4 PF11465.8 KND86119.1 - 0.094 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 adh_short_C2 PF13561.6 KND86120.1 - 1.6e-37 129.3 2.5 2.3e-37 128.8 2.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND86120.1 - 1.2e-31 109.7 1.1 1.5e-31 109.4 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND86120.1 - 3.2e-11 43.5 0.3 4.8e-11 42.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND86120.1 - 0.0086 15.2 0.1 0.012 14.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KND86120.1 - 0.057 12.9 0.1 0.2 11.1 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_PK PF05891.12 KND86122.1 - 5e-40 137.4 0.0 6e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 KND86122.1 - 0.073 12.4 0.1 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase domain F-box PF00646.33 KND86123.1 - 4.2e-05 23.3 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain DPM3 PF08285.11 KND86123.1 - 0.043 14.0 0.2 0.12 12.5 0.2 1.7 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) APH PF01636.23 KND86124.1 - 1.5e-11 44.7 0.0 5.1e-11 43.0 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF2744 PF10910.8 KND86124.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) Uma2 PF05685.12 KND86129.1 - 0.072 12.6 0.1 0.41 10.2 0.1 2.0 1 1 0 1 1 1 0 Putative restriction endonuclease DUF2406 PF10295.9 KND86130.1 - 0.081 13.6 0.2 0.25 12.0 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein (DUF2406) Kinesin PF00225.23 KND86133.1 - 3.3e-55 187.3 0.0 7.9e-55 186.1 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND86133.1 - 1.1e-08 35.1 0.0 5.2e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Herpes_BLRF2 PF05812.12 KND86133.1 - 0.013 15.7 3.0 0.025 14.7 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein APC_N_CC PF16689.5 KND86133.1 - 0.02 15.0 0.2 0.043 13.9 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Cep57_CLD_2 PF14197.6 KND86133.1 - 0.051 13.7 2.0 4.9 7.3 0.2 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 NRBF2 PF08961.10 KND86133.1 - 0.052 13.2 3.2 1 8.9 0.1 2.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator bZIP_2 PF07716.15 KND86133.1 - 0.28 11.3 3.9 1.7 8.8 1.3 2.5 2 0 0 2 2 2 0 Basic region leucine zipper Lzipper-MIP1 PF14389.6 KND86133.1 - 0.71 10.2 3.6 1.4 9.3 1.0 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.9 KND86133.1 - 7.2 6.8 10.3 18 5.5 8.5 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KND86133.1 - 7.8 7.2 7.4 60 4.4 0.2 2.8 2 0 0 2 2 2 0 SlyX Ank_2 PF12796.7 KND86134.1 - 3.5e-31 107.6 0.0 3.5e-12 46.7 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86134.1 - 8.5e-29 99.6 0.0 1.8e-10 41.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KND86134.1 - 8e-25 86.1 0.0 0.0037 17.6 0.0 7.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KND86134.1 - 1.3e-19 68.2 0.0 0.012 16.1 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KND86134.1 - 1.2e-17 63.7 0.4 9.7e-05 22.6 0.0 4.9 3 3 2 5 5 5 4 Ankyrin repeats (many copies) GATase_7 PF13537.6 KND86134.1 - 0.00043 20.2 0.1 6.3 6.7 0.0 4.5 2 1 2 4 4 4 1 Glutamine amidotransferase domain NACHT PF05729.12 KND86134.1 - 0.00063 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain GATase_6 PF13522.6 KND86134.1 - 0.025 14.8 0.1 1.3 9.2 0.1 3.0 2 1 1 3 3 3 0 Glutamine amidotransferase domain AvrPtoB_bdg PF16847.5 KND86134.1 - 0.44 11.1 2.4 1.8 9.1 0.2 3.0 2 1 1 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain p450 PF00067.22 KND86135.1 - 1.2e-57 195.8 0.0 1.5e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TMEM252 PF15664.5 KND86136.1 - 0.1 12.3 0.3 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Ribosomal_60s PF00428.19 KND86136.1 - 4.2 8.0 14.4 2 9.1 9.2 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.25 KND86139.1 - 2.3e-11 43.6 0.0 1.1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND86139.1 - 0.00024 20.5 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND86139.1 - 0.0031 16.9 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KND86139.1 - 0.012 15.6 0.1 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.11 KND86139.1 - 0.22 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KND86141.1 - 1.9e-13 50.4 0.0 3.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 KND86141.1 - 1.2e-12 48.3 0.8 4.3e-06 26.8 0.1 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KND86141.1 - 2.7e-06 26.9 0.0 5.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KND86141.1 - 1.1e-05 25.2 0.0 0.0098 15.5 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KND86141.1 - 1.2e-05 24.7 0.0 0.00045 19.6 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase RIO1 PF01163.22 KND86141.1 - 9e-05 22.2 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 RIO1 family DUF1679 PF07914.11 KND86141.1 - 0.00019 20.4 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Lipase_3 PF01764.25 KND86143.1 - 1.4e-31 109.3 0.0 1.9e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KND86143.1 - 0.0002 22.0 0.1 0.00026 21.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND86143.1 - 0.00053 19.3 0.0 0.00087 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KND86143.1 - 0.00058 20.0 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 KND86143.1 - 0.025 14.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KND86143.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold TUG-UBL1 PF11470.8 KND86146.1 - 2.2e-25 88.6 0.1 4.5e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KND86146.1 - 0.0012 18.8 0.3 0.0035 17.4 0.2 1.8 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF4294 PF14127.6 KND86146.1 - 0.0032 17.4 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) Pex14_N PF04695.13 KND86146.1 - 8.2 7.1 15.1 20 5.8 15.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Proteasome PF00227.26 KND86147.1 - 4e-40 137.4 0.0 4.8e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 KND86148.1 - 7.4e-48 162.5 3.8 2.1e-47 161.0 1.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND86148.1 - 5.3e-46 156.6 3.5 5.3e-46 156.6 3.5 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KND86148.1 - 1.3e-20 73.3 0.0 2.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND86148.1 - 3.4e-19 70.0 0.4 3.9e-18 66.5 0.4 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND86148.1 - 4.3e-18 64.8 0.1 1e-17 63.6 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND86148.1 - 2.9e-07 30.5 1.1 4.7e-06 26.5 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND86148.1 - 5.5e-05 23.7 0.0 0.00022 21.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND86149.1 - 1e-45 155.5 5.7 2.6e-45 154.2 5.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KND86149.1 - 1.8e-23 84.0 0.1 2.8e-23 83.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND86149.1 - 1.5e-07 31.4 0.2 1.3e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KND86149.1 - 1.3e-05 25.6 1.7 1.8e-05 25.1 0.2 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain YjeF_N PF03853.15 KND86149.1 - 0.00031 20.7 0.7 0.71 9.7 0.1 3.3 3 0 0 3 3 3 2 YjeF-related protein N-terminus Hc1 PF07432.13 KND86149.1 - 0.07 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Histone H1-like protein Hc1 S6PP PF05116.13 KND86149.1 - 0.097 12.2 0.1 27 4.2 0.0 3.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase SNARE PF05739.19 KND86150.1 - 7.7e-14 51.4 0.2 7.7e-14 51.4 0.2 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 KND86150.1 - 5.9e-09 34.9 0.3 5.9e-09 34.9 0.3 1.9 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KND86150.1 - 0.00033 20.4 8.3 0.0015 18.2 0.1 3.1 2 1 1 3 3 3 1 Syntaxin KxDL PF10241.9 KND86150.1 - 0.0017 18.6 6.0 0.098 13.0 0.3 3.6 4 0 0 4 4 4 2 Uncharacterized conserved protein TRPM_tetra PF16519.5 KND86150.1 - 0.0095 16.0 2.5 0.021 14.9 0.1 2.8 3 0 0 3 3 3 1 Tetramerisation domain of TRPM Prominin PF05478.11 KND86150.1 - 0.013 13.5 2.2 0.86 7.5 0.0 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 KND86150.1 - 0.023 14.9 1.2 0.14 12.4 0.3 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.21 KND86150.1 - 0.024 14.4 5.1 0.058 13.2 0.5 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SOAR PF16533.5 KND86150.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.6 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF4988 PF16378.5 KND86150.1 - 0.14 11.8 4.2 12 5.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KND86150.1 - 0.19 12.2 4.2 29 5.2 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.11 KND86150.1 - 0.3 10.4 4.6 0.42 9.9 1.1 2.4 2 0 0 2 2 2 0 SF-assemblin/beta giardin FliS_cochap PF16522.5 KND86150.1 - 0.38 10.7 4.3 5.1 7.0 0.1 3.1 3 1 0 3 3 3 0 Flagellar FLiS export co-chaperone, HP1076 Aldo_ket_red PF00248.21 KND86151.1 - 1.2e-42 146.1 0.0 2.4e-36 125.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family DUF1833 PF08875.11 KND86151.1 - 0.072 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) ADH_N PF08240.12 KND86152.1 - 5.9e-26 90.5 1.8 5.9e-26 90.5 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND86152.1 - 1.4e-15 57.4 0.9 3.2e-15 56.3 0.9 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND86152.1 - 1.1e-09 38.1 0.7 8.7e-05 22.1 0.1 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus YdfZ PF14001.6 KND86152.1 - 0.053 13.9 0.4 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 YdfZ protein AlaDh_PNT_C PF01262.21 KND86152.1 - 9.1 5.5 16.4 0.17 11.2 3.9 2.9 3 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 KND86153.1 - 5.2e-23 81.7 0.0 7.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PBD PF00786.28 KND86153.1 - 2.8e-21 75.6 0.0 5.4e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_Tyr PF07714.17 KND86153.1 - 8.2e-14 51.5 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 KND86153.1 - 0.077 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 KND86153.1 - 0.13 12.7 0.7 0.81 10.1 0.7 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain TPR_10 PF13374.6 KND86154.1 - 4.4e-66 217.1 19.4 9.1e-13 47.6 0.0 8.5 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 KND86154.1 - 9.5e-54 179.6 15.2 2.3e-13 50.2 0.1 6.5 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 KND86154.1 - 4.4e-18 63.9 5.7 0.00055 19.8 0.0 7.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KND86154.1 - 9.4e-13 47.2 10.2 0.0034 17.4 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND86154.1 - 1.5e-07 30.9 3.7 1.5 8.7 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 KND86154.1 - 2.3e-07 30.3 0.3 0.0078 15.4 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain TPR_4 PF07721.14 KND86154.1 - 5.2e-07 29.7 12.5 0.58 10.9 0.0 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND86154.1 - 1.9e-06 27.6 4.9 2.3 8.7 0.0 6.2 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND86154.1 - 2.9e-05 24.5 0.9 15 6.2 0.0 5.0 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 KND86154.1 - 5.2e-05 23.3 8.4 2 9.0 0.0 6.3 7 1 1 8 8 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KND86154.1 - 7.3e-05 23.2 0.3 0.00033 21.1 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain TPR_MalT PF17874.1 KND86154.1 - 8.2e-05 22.1 12.8 0.0018 17.7 3.9 3.5 1 1 2 3 3 3 2 MalT-like TPR region AAA_22 PF13401.6 KND86154.1 - 0.00013 22.2 0.0 0.00049 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain PLU-1 PF08429.11 KND86154.1 - 0.0014 17.9 2.3 0.015 14.4 0.3 2.5 1 1 1 2 2 2 1 PLU-1-like protein TPR_16 PF13432.6 KND86154.1 - 0.0033 18.1 6.6 0.89 10.3 0.0 5.8 5 2 1 6 6 5 1 Tetratricopeptide repeat NACHT PF05729.12 KND86154.1 - 0.0035 17.3 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SNAP PF14938.6 KND86154.1 - 0.017 14.6 0.3 1.1 8.6 0.0 2.4 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP PALP PF00291.25 KND86154.1 - 0.025 14.0 0.0 8.7 5.7 0.0 2.8 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme TPR_9 PF13371.6 KND86154.1 - 0.092 12.9 0.1 0.3 11.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND86154.1 - 0.098 13.3 2.0 19 6.1 0.1 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND86154.1 - 0.26 12.2 6.4 33 5.7 0.0 5.8 7 0 0 7 7 4 0 Tetratricopeptide repeat HNH_2 PF13391.6 KND86155.1 - 1.6e-12 47.4 0.0 4.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Glyco_transf_25 PF01755.17 KND86159.1 - 0.18 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) APH PF01636.23 KND86162.1 - 0.0052 16.7 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86162.1 - 0.008 15.8 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KND86166.1 - 2e-06 27.4 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KND86166.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KND86166.1 - 0.002 17.0 1.0 0.0086 14.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Radial_spoke_3 PF06098.11 KND86166.1 - 0.0038 16.6 7.0 0.0073 15.6 7.0 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 HSDR_N_2 PF13588.6 KND86166.1 - 0.012 15.6 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.23 KND86166.1 - 0.075 12.9 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Methyltransf_4 PF02390.17 KND86166.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF390 PF04094.14 KND86166.1 - 0.48 8.7 11.3 0.82 7.9 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Macoilin PF09726.9 KND86166.1 - 1.9 7.0 11.4 7.3 5.0 12.2 1.4 2 0 0 2 2 2 0 Macoilin family NARP1 PF12569.8 KND86166.1 - 2.1 7.1 5.7 3.1 6.6 5.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FemAB PF02388.16 KND86166.1 - 3.9 6.2 4.4 6.4 5.5 4.4 1.3 1 0 0 1 1 1 0 FemAB family U79_P34 PF03064.16 KND86166.1 - 5.7 6.2 11.4 11 5.3 11.4 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 APH PF01636.23 KND86167.1 - 7.6e-06 26.0 0.0 8.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KND86167.1 - 0.00032 20.1 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fructosamin_kin PF03881.14 KND86167.1 - 0.029 13.6 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.17 KND86167.1 - 0.044 13.1 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KND86168.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KND86170.1 - 1.7e-13 51.1 0.2 1.3e-12 48.2 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86170.1 - 5.6e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KND86170.1 - 0.0051 16.0 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.11 KND86170.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ank_2 PF12796.7 KND86173.1 - 1.5e-13 51.1 4.0 4.6e-08 33.5 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86173.1 - 4.2e-08 33.6 1.7 7.9e-06 26.3 0.5 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86173.1 - 6.4e-07 29.2 6.2 0.047 14.2 0.1 4.1 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 KND86173.1 - 9.5e-07 29.0 9.7 0.00063 20.1 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KND86173.1 - 4.7e-06 26.8 3.5 0.054 13.8 0.1 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Casc1_N PF15927.5 KND86175.1 - 0.72 9.5 13.9 1.4 8.5 13.9 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ank_2 PF12796.7 KND86177.1 - 6.5e-08 33.1 0.1 3.5e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND86177.1 - 2.6e-05 24.4 0.1 0.037 14.4 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KND86177.1 - 3.9e-05 23.9 1.8 0.0057 17.0 0.1 3.4 3 1 1 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KND86177.1 - 4.5e-05 23.9 0.4 0.024 15.2 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86177.1 - 0.00012 22.2 0.1 0.097 13.3 0.0 3.5 3 1 0 3 3 3 1 Ankyrin repeat Pkinase PF00069.25 KND86178.1 - 0.039 13.3 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain BCS1_N PF08740.11 KND86180.1 - 3.5e-31 108.7 0.9 7.2e-31 107.6 0.9 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KND86180.1 - 2.6e-08 34.4 0.0 6.5e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND86180.1 - 0.00077 19.2 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND86180.1 - 0.0059 17.0 0.0 0.022 15.2 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KND86180.1 - 0.013 15.7 0.0 0.065 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 KND86180.1 - 0.022 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 KND86180.1 - 0.034 14.4 0.0 1.6 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KND86180.1 - 0.039 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KND86180.1 - 0.078 12.5 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 KND86180.1 - 0.085 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_11 PF13086.6 KND86180.1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 KND86181.1 - 6.8e-17 61.8 0.0 1.1e-11 45.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86181.1 - 8.9e-15 54.9 0.0 1.7e-09 38.0 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND86181.1 - 2.8e-12 46.6 0.6 0.0005 20.3 0.1 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KND86181.1 - 6.2e-12 45.4 0.6 0.00082 19.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KND86181.1 - 1.8e-10 40.1 0.7 0.0097 16.4 0.0 4.2 5 0 0 5 5 5 2 Ankyrin repeat DUF3716 PF12511.8 KND86182.1 - 2.4e-09 37.1 4.8 4.7e-09 36.1 4.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-RING_6 PF14835.6 KND86182.1 - 0.059 13.3 2.5 0.12 12.2 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Tnp_zf-ribbon_2 PF13842.6 KND86182.1 - 5.4 7.9 9.2 2.2 9.2 1.2 2.7 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DUF3435 PF11917.8 KND86183.1 - 3.7e-118 395.1 1.8 4.8e-118 394.7 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integr_3 PF16795.5 KND86183.1 - 0.019 14.9 0.0 0.049 13.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal phage integrase Taxilin PF09728.9 KND86183.1 - 0.033 13.4 6.8 0.064 12.4 6.8 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein BRE1 PF08647.11 KND86183.1 - 0.94 9.6 6.8 0.26 11.4 3.0 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase zf-C2H2 PF00096.26 KND86183.1 - 3.3 8.3 6.6 31 5.3 0.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type COesterase PF00135.28 KND86185.1 - 1.9e-87 294.3 0.0 2.9e-87 293.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KND86185.1 - 9.5e-07 28.9 0.0 1.6e-05 24.9 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND86185.1 - 0.016 14.7 0.2 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Arylesterase PF01731.20 KND86186.1 - 0.00072 19.7 0.1 0.0018 18.4 0.1 1.8 1 1 0 1 1 1 1 Arylesterase Abi_C PF14355.6 KND86186.1 - 0.035 14.2 0.2 4.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus TRP PF06011.12 KND86187.1 - 1.2e-148 495.4 28.3 1.4e-148 495.2 28.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND86187.1 - 2.1e-40 138.3 0.1 3.2e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.16 KND86188.1 - 3.8e-42 144.5 27.5 3.8e-42 144.5 27.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86188.1 - 1.7e-14 53.5 20.3 2.8e-14 52.8 20.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TraL PF07178.11 KND86188.1 - 3 8.4 0.0 3 8.4 0.0 4.3 5 2 1 6 6 6 0 TraL protein 3HCDH PF00725.22 KND86189.1 - 1.3e-20 73.8 0.2 6.7e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 KND86189.1 - 4.8e-11 42.9 0.0 9.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 KND86189.1 - 1.7e-07 31.2 7.9 3.6e-07 30.2 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.12 KND86190.1 - 5.6e-22 78.5 0.1 8.4e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KND86190.1 - 0.0004 20.5 0.1 0.0019 18.3 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 KND86190.1 - 0.0008 19.5 0.0 0.0028 17.7 0.0 2.0 2 1 0 2 2 2 1 Strictosidine synthase Sugar_tr PF00083.24 KND86193.1 - 2.3e-94 316.8 19.9 8.1e-94 315.0 19.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86193.1 - 8.1e-08 31.6 13.6 8.1e-08 31.6 13.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily APH PF01636.23 KND86194.1 - 5.5e-15 55.9 0.0 9.3e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86194.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND86194.1 - 0.19 11.3 0.0 0.6 9.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Lipocalin_2 PF08212.12 KND86197.1 - 0.029 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain IDO PF01231.18 KND86198.1 - 5.8e-124 414.2 0.0 7.1e-124 413.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KND86198.1 - 0.21 10.3 0.0 0.89 8.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1864) MFS_1 PF07690.16 KND86199.1 - 1.7e-27 96.3 54.6 2.6e-17 62.8 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND86199.1 - 0.00052 19.0 2.7 0.00052 19.0 2.7 3.9 2 2 2 4 4 4 3 MFS_1 like family NACHT PF05729.12 KND86202.1 - 4.8e-13 49.4 0.0 8.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND86202.1 - 1.6e-06 28.7 1.7 3.9e-06 27.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND86202.1 - 0.00014 22.2 0.0 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KND86202.1 - 0.00094 18.8 0.2 0.0076 15.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND86202.1 - 0.021 15.2 0.0 0.07 13.5 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KND86202.1 - 0.044 13.0 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KND86202.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KND86202.1 - 0.078 13.4 0.1 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KND86202.1 - 0.096 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 KND86202.1 - 0.12 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KND86202.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Hexokinase_2 PF03727.16 KND86202.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Hexokinase DUF2075 PF09848.9 KND86202.1 - 0.18 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltransf_23 PF13489.6 KND86204.1 - 3.4e-05 23.8 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PALP PF00291.25 KND86205.1 - 7.2e-70 235.7 0.1 1.2e-69 235.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KND86205.1 - 2.1e-12 47.3 0.0 3.7e-08 33.7 0.0 3.0 3 0 0 3 3 3 2 CBS domain Ank_2 PF12796.7 KND86206.1 - 6.6e-33 113.1 0.1 1.9e-13 50.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 KND86206.1 - 3.8e-30 104.7 16.0 3.8e-30 104.7 16.0 2.4 2 2 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 KND86206.1 - 3.3e-23 81.7 1.3 8.4e-08 32.6 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND86206.1 - 7.8e-21 73.9 0.1 3.5e-05 24.0 0.0 4.7 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86206.1 - 8.6e-20 68.7 0.8 3.3e-07 30.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 KND86206.1 - 2.1e-18 65.8 0.7 3e-05 24.2 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat MRP-L51 PF10244.9 KND86206.1 - 0.083 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit ERCC3_RAD25_C PF16203.5 KND86207.1 - 1.9e-94 315.5 1.1 3.4e-84 281.9 0.1 2.3 1 1 1 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KND86207.1 - 4.4e-31 107.7 0.0 1.5e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND86207.1 - 3.2e-13 50.0 0.0 5.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND86207.1 - 1e-10 41.9 0.0 3.3e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KND86207.1 - 2.8e-07 29.6 0.0 3.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Peptidase_M28 PF04389.17 KND86208.1 - 1.8e-30 106.1 0.0 2.8e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KND86208.1 - 1.5e-08 34.5 0.2 4e-08 33.2 0.1 1.7 2 0 0 2 2 2 1 PA domain HNH_2 PF13391.6 KND86209.1 - 7.6e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease TRAPPC-Trs85 PF12739.7 KND86212.1 - 0.028 13.4 0.4 0.082 11.9 0.4 1.6 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ank_2 PF12796.7 KND86213.1 - 6.7e-05 23.4 0.0 7.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KND86213.1 - 0.00018 21.8 0.0 0.00028 21.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 KND86213.1 - 0.00044 20.5 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND86213.1 - 0.00058 20.4 0.0 0.2 12.3 0.0 1.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86213.1 - 0.00073 19.8 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Pkinase PF00069.25 KND86214.1 - 9.8e-27 94.0 0.0 1.2e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86214.1 - 5.7e-12 45.5 0.0 6.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND86214.1 - 1.7e-07 30.4 0.1 2.4e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND86214.1 - 0.00021 21.3 0.0 0.024 14.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF4188 PF13826.6 KND86217.1 - 0.052 13.9 0.1 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4188) DnaJ PF00226.31 KND86217.1 - 0.077 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain DUF4379 PF14311.6 KND86218.1 - 0.092 13.1 0.1 17 5.9 0.1 2.8 2 0 0 2 2 2 0 Probable Zinc-ribbon domain MgsA_C PF12002.8 KND86218.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Glyco_hydro_18 PF00704.28 KND86219.1 - 1.5e-09 38.0 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KND86220.1 - 9.2e-22 78.2 0.2 4.1e-15 56.3 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 APH PF01636.23 KND86221.1 - 3.2e-18 66.5 3.0 4.1e-18 66.2 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86221.1 - 0.02 14.5 0.3 0.3 10.6 0.0 2.5 2 1 0 2 2 2 0 Choline/ethanolamine kinase Zn_clus PF00172.18 KND86222.1 - 1.6e-08 34.5 7.6 1.6e-08 34.5 7.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Evr1_Alr PF04777.13 KND86222.1 - 0.17 12.4 2.0 0.24 11.9 2.0 1.4 1 1 0 1 1 1 0 Erv1 / Alr family K_oxygenase PF13434.6 KND86224.1 - 4.9e-11 42.4 0.0 6.3e-06 25.6 0.0 3.2 3 0 0 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KND86224.1 - 1.5e-08 33.6 0.0 8.3e-08 31.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KND86224.1 - 3.6e-06 26.4 0.0 0.026 13.7 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND86224.1 - 2.6e-05 23.6 0.0 0.0055 16.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND86224.1 - 0.00036 20.7 0.1 0.00094 19.4 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KND86224.1 - 0.0017 18.4 2.8 1.3 9.0 0.0 3.3 3 1 1 4 4 4 2 FAD-NAD(P)-binding Mqo PF06039.15 KND86224.1 - 0.01 14.4 0.0 0.15 10.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 KND86224.1 - 0.031 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Exo_endo_phos PF03372.23 KND86226.1 - 0.00047 19.8 0.4 0.0016 18.0 0.2 2.0 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_3 PF07859.13 KND86227.1 - 1.9e-28 99.8 0.1 2.7e-28 99.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND86227.1 - 1.7e-08 33.7 0.0 2.7e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 KND86227.1 - 0.042 13.6 0.0 0.6 9.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Methyltransf_3 PF01596.17 KND86228.1 - 6.4e-30 103.9 0.0 1.2e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 KND86228.1 - 2.9e-12 46.8 0.0 4.1e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KND86228.1 - 2.4e-10 40.4 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KND86228.1 - 3.8e-10 40.7 0.0 8.4e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86228.1 - 7.4e-08 33.0 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND86228.1 - 0.00048 20.7 0.0 0.0012 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND86228.1 - 0.0005 19.6 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 KND86228.1 - 0.0026 18.5 0.0 0.0041 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KND86228.1 - 0.0048 16.6 0.0 0.0063 16.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KND86228.1 - 0.022 14.1 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Response_reg PF00072.24 KND86228.1 - 0.031 14.4 0.0 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Response regulator receiver domain Fibrillarin PF01269.17 KND86228.1 - 0.073 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.20 KND86228.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Hydantoinase_A PF01968.18 KND86229.1 - 2e-11 43.7 5.6 3.9e-10 39.5 1.9 2.3 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase DUF917 PF06032.12 KND86229.1 - 1.7e-05 23.9 1.1 4.3e-05 22.5 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Fe-ADH PF00465.19 KND86229.1 - 0.057 12.2 0.1 0.057 12.2 0.1 1.6 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase DUF917 PF06032.12 KND86230.1 - 5.3e-50 170.2 0.0 2e-27 95.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF917) FAD_binding_3 PF01494.19 KND86231.1 - 3.6e-14 52.8 6.2 2.8e-12 46.6 0.3 2.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND86231.1 - 2.3e-05 24.5 0.4 6.3e-05 23.1 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND86231.1 - 0.00041 19.7 0.3 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND86231.1 - 0.0071 15.5 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND86231.1 - 0.014 15.0 7.7 0.19 11.2 5.1 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase SE PF08491.10 KND86231.1 - 0.028 13.5 0.0 0.29 10.1 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase Amino_oxidase PF01593.24 KND86231.1 - 0.045 13.0 0.2 0.79 8.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KND86231.1 - 0.048 13.6 3.2 0.68 9.9 1.5 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KND86231.1 - 0.071 12.0 2.9 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 KND86231.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KND86231.1 - 0.17 12.4 0.3 0.48 11.0 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND86231.1 - 0.2 10.3 0.6 0.3 9.7 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein GMC_oxred_N PF00732.19 KND86232.1 - 1e-56 192.5 0.0 1.8e-56 191.7 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND86232.1 - 8.7e-33 113.9 0.7 2.6e-32 112.3 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND86232.1 - 4.8e-06 25.9 4.6 0.001 18.2 1.0 2.7 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 KND86232.1 - 2.9e-05 23.3 0.4 0.00015 21.0 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KND86232.1 - 4e-05 23.7 0.5 0.00018 21.7 0.5 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND86232.1 - 5.4e-05 22.6 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND86232.1 - 0.0011 18.6 2.3 0.011 15.4 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND86232.1 - 0.0022 16.8 0.4 0.012 14.3 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KND86232.1 - 0.0023 17.2 1.0 0.022 14.0 0.3 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KND86232.1 - 0.0082 16.4 0.2 0.027 14.7 0.0 2.0 3 0 0 3 3 1 1 TrkA-N domain FAD_binding_3 PF01494.19 KND86232.1 - 0.014 14.6 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KND86232.1 - 0.038 14.6 0.2 0.33 11.6 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND86232.1 - 0.19 10.5 0.1 0.31 9.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 KND86232.1 - 0.2 10.9 0.3 0.36 10.0 0.3 1.3 1 0 0 1 1 1 0 Thi4 family DEAD PF00270.29 KND86234.1 - 3.1e-42 144.3 0.0 5.4e-41 140.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND86234.1 - 5.4e-21 75.0 0.0 4.8e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND86234.1 - 1.9e-06 28.0 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KND86234.1 - 0.00082 19.3 0.0 0.0053 16.6 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_30 PF13604.6 KND86234.1 - 0.014 15.1 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KND86234.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KND86234.1 - 0.21 11.9 0.2 1.5 9.1 0.6 2.2 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KND86235.1 - 5.8e-11 41.9 3.6 1.1e-10 41.0 3.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KND86236.1 - 1.9e-12 46.7 0.9 2.8e-12 46.2 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86236.1 - 1.4e-07 31.5 12.8 2.6e-07 30.6 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydant_A_N PF05378.13 KND86237.1 - 1.7e-13 50.7 0.2 1.9e-13 50.5 0.2 1.0 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region DUF760 PF05542.11 KND86237.1 - 0.032 14.6 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF760) S_layer_N PF05123.12 KND86237.1 - 0.073 12.9 1.8 0.097 12.5 1.8 1.0 1 0 0 1 1 1 0 S-layer like family, N-terminal region Transp_cyt_pur PF02133.15 KND86238.1 - 1.4e-37 129.6 10.9 1.7e-37 129.2 10.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sugar_tr PF00083.24 KND86239.1 - 4.6e-64 217.0 19.6 5.5e-64 216.7 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86239.1 - 1.2e-07 31.0 41.6 0.00029 19.9 20.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND86239.1 - 0.00042 19.0 3.2 0.00042 19.0 3.2 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein zinc_ribbon_9 PF14369.6 KND86240.1 - 0.055 13.7 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon DUF2768 PF10966.8 KND86240.1 - 0.24 11.8 4.4 0.34 11.4 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) SBF PF01758.16 KND86241.1 - 3.7e-14 52.8 6.0 7.9e-11 42.0 3.4 2.8 2 1 1 3 3 3 2 Sodium Bile acid symporter family HKR_ArcB_TM PF18415.1 KND86241.1 - 1.1 10.1 9.4 7.2 7.5 1.6 2.8 1 1 1 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Kdo PF06293.14 KND86242.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_31 PF13847.6 KND86244.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86244.1 - 0.048 14.4 0.0 0.057 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain CDC4_D PF16856.5 KND86244.1 - 0.052 13.4 0.2 0.13 12.2 0.2 1.7 1 1 1 2 2 2 0 Cell division control protein 4 dimerisation domain Pkinase_fungal PF17667.1 KND86245.1 - 2.8e-15 56.0 0.4 4.2e-15 55.5 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KND86245.1 - 1.3e-12 47.7 0.0 1.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86245.1 - 2.1e-05 24.0 0.1 3.6e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND86245.1 - 0.00014 21.3 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND86245.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.23 KND86248.1 - 1.9e-14 53.7 0.3 3.8e-14 52.7 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APH PF01636.23 KND86254.1 - 7e-14 52.3 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND86254.1 - 0.00053 19.6 0.0 0.0039 16.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KND86254.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KND86254.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DAO PF01266.24 KND86255.1 - 0.16 11.5 0.0 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sel1 PF08238.12 KND86257.1 - 7.2e-36 121.8 28.4 6.5e-07 29.8 0.1 8.0 7 0 0 7 7 7 7 Sel1 repeat MFS_1 PF07690.16 KND86257.1 - 2.3e-33 115.6 26.7 2.3e-33 115.6 26.7 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86257.1 - 8.2e-09 34.8 9.0 8.2e-09 34.8 9.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4281 PF14108.6 KND86257.1 - 0.017 15.5 1.1 0.017 15.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) TRI12 PF06609.13 KND86257.1 - 0.037 12.4 8.9 0.0087 14.5 4.8 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OPT PF03169.15 KND86260.1 - 2e-179 598.2 54.4 2.2e-179 598.0 54.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2937 PF11157.8 KND86260.1 - 0.12 12.1 0.1 6.3 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF3638 PF12340.8 KND86261.1 - 2.2e-100 334.7 0.5 4.9e-100 333.5 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KND86261.1 - 2.3e-18 65.3 0.1 5.1e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-NPL4 PF05020.15 KND86261.1 - 0.15 12.2 0.7 0.38 10.9 0.7 1.6 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region Fumble PF03630.14 KND86262.1 - 1.8e-142 474.4 0.1 2.3e-142 474.1 0.1 1.1 1 0 0 1 1 1 1 Fumble TPR_12 PF13424.6 KND86264.1 - 3.6e-05 24.0 1.3 0.33 11.3 0.1 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND86264.1 - 0.0021 17.8 1.7 0.13 12.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND86264.1 - 0.0052 17.5 0.7 2.7 9.0 0.3 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND86264.1 - 0.017 15.6 0.6 0.13 12.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND86264.1 - 0.025 15.2 0.7 0.025 15.2 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND86264.1 - 0.12 12.5 2.0 3 8.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND86264.1 - 0.14 12.4 0.4 2.1 8.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND86264.1 - 0.19 11.6 0.1 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 KND86265.1 - 2e-09 37.4 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KND86265.1 - 0.15 11.6 0.0 0.54 9.8 0.0 1.8 1 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KND86266.1 - 1.4e-34 119.6 37.1 9.6e-34 116.8 15.1 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86266.1 - 1.4e-10 40.7 12.1 1.4e-10 40.7 12.1 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND86266.1 - 0.0029 16.1 3.9 0.0042 15.6 3.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPT_ssu-like PF11779.8 KND86266.1 - 0.37 10.4 3.1 0.93 9.2 1.0 2.6 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like 2TM PF13239.6 KND86266.1 - 5.3 7.4 5.0 34 4.8 0.3 3.6 3 0 0 3 3 3 0 2TM domain BTB PF00651.31 KND86269.1 - 3.5e-13 49.8 0.1 6.1e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.6 KND86271.1 - 4.2e-05 23.5 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86271.1 - 0.00019 22.1 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86271.1 - 0.00025 20.9 0.0 0.00048 19.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KND86271.1 - 0.00056 19.5 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KND86271.1 - 0.02 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 KND86271.1 - 0.023 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 KND86271.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KND86271.1 - 0.08 12.2 0.0 0.087 12.1 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Cyclin_N PF00134.23 KND86273.1 - 8.2e-13 48.2 0.1 1.6e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KND86273.1 - 0.0034 17.8 0.2 0.006 17.0 0.2 1.4 1 1 0 1 1 1 1 Cyclin DUF1752 PF08550.10 KND86274.1 - 1.2e-09 37.8 8.0 2.5e-09 36.8 8.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF676 PF05057.14 KND86275.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND86275.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND86275.1 - 0.005 17.5 0.0 0.0067 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND86275.1 - 0.0071 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND86275.1 - 0.036 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 KND86275.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase_fungal PF17667.1 KND86276.1 - 3.8e-105 352.0 0.0 5e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KND86276.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FAD_binding_4 PF01565.23 KND86277.1 - 2.9e-25 88.6 4.3 4.3e-25 88.1 4.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND86277.1 - 5.5e-12 45.6 0.2 1.4e-11 44.3 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like TPP_enzyme_N PF02776.18 KND86278.1 - 9.2e-35 119.8 0.0 2.4e-33 115.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KND86278.1 - 1.3e-20 73.8 0.0 3.1e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND86278.1 - 2.7e-10 40.1 0.0 3.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Nramp PF01566.18 KND86280.1 - 2.3e-87 293.3 19.6 7.6e-87 291.6 19.6 1.8 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein WD40 PF00400.32 KND86281.1 - 6e-31 106.0 16.1 6.9e-08 33.0 0.0 8.5 8 1 0 8 8 8 6 WD domain, G-beta repeat NACHT PF05729.12 KND86281.1 - 1.6e-20 73.6 0.0 3.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KND86281.1 - 3.8e-16 59.2 0.1 0.00011 22.4 0.0 6.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND86281.1 - 3.6e-05 22.9 0.4 0.21 10.5 0.0 4.3 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 KND86281.1 - 0.0001 22.7 0.2 0.0005 20.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Nup160 PF11715.8 KND86281.1 - 0.00041 19.1 0.5 0.072 11.7 0.0 3.0 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 KND86281.1 - 0.013 15.4 0.5 27 4.8 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KND86281.1 - 0.021 14.1 0.1 1.2 8.4 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain AAA_22 PF13401.6 KND86281.1 - 0.025 14.8 0.0 0.16 12.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain potato_inhibit PF00280.18 KND86281.1 - 0.049 14.3 0.0 7.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Potato inhibitor I family RNA_helicase PF00910.22 KND86281.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 KND86281.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain CPSF73-100_C PF11718.8 KND86283.1 - 5.7e-11 42.4 0.3 1.2e-09 38.1 0.3 2.1 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term UDPG_MGDP_dh PF00984.19 KND86284.1 - 8.5e-20 70.8 0.0 2.8e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 KND86284.1 - 3.5e-15 56.1 0.1 2.9e-13 49.8 0.1 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 KND86284.1 - 6.2e-05 23.2 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 KND86284.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain XdhC_C PF13478.6 KND86284.1 - 0.079 13.5 0.1 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Sacchrp_dh_NADP PF03435.18 KND86284.1 - 0.15 12.3 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_deac_1 PF01522.21 KND86285.1 - 4.3e-21 75.1 0.0 6.6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KND86285.1 - 3.8e-09 36.9 44.6 2.7e-07 31.0 15.9 3.8 3 0 0 3 3 3 3 Chitin recognition protein Chitin_synth_2 PF03142.15 KND86286.1 - 9.2e-39 133.4 4.5 1.9e-25 89.5 0.6 3.2 3 0 0 3 3 3 3 Chitin synthase Glycos_transf_2 PF00535.26 KND86286.1 - 7.3e-08 32.4 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 KND86286.1 - 0.00025 21.0 5.1 0.00025 21.0 5.1 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND86286.1 - 0.00077 19.4 0.5 1.1 9.0 0.0 3.1 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_transf_6 PF03414.13 KND86286.1 - 0.0075 15.1 0.3 0.013 14.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 6 YiaAB PF05360.14 KND86286.1 - 0.68 10.2 6.0 6 7.2 0.1 3.0 2 0 0 2 2 2 0 yiaA/B two helix domain Pkinase PF00069.25 KND86288.1 - 1.9e-10 40.6 0.0 3.4e-10 39.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86288.1 - 7.4e-07 28.7 0.0 2.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KND86288.1 - 0.00011 21.7 0.0 0.00021 20.7 0.0 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND86288.1 - 0.00078 19.4 0.4 0.0025 17.8 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND86288.1 - 0.0069 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 KND86288.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND86288.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KND86288.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ABC_tran PF00005.27 KND86291.1 - 7.8e-35 120.4 0.4 2.4e-25 89.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND86291.1 - 1.3e-17 64.4 6.9 4.9e-10 39.5 1.2 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KND86291.1 - 1.2e-10 41.2 0.1 4.5e-05 23.0 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND86291.1 - 3.3e-09 37.0 0.8 0.018 14.8 0.1 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND86291.1 - 0.00032 20.4 0.0 0.0009 18.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KND86291.1 - 0.0017 18.5 1.6 0.72 10.1 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 KND86291.1 - 0.0032 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_16 PF13191.6 KND86291.1 - 0.0043 17.5 0.5 0.012 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KND86291.1 - 0.0043 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KND86291.1 - 0.009 16.1 0.1 0.04 14.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND86291.1 - 0.0094 15.9 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 KND86291.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 KND86291.1 - 0.013 15.7 0.0 0.064 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND86291.1 - 0.014 15.4 0.1 0.32 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KND86291.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KND86291.1 - 0.031 14.0 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 KND86291.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TMEM189_B_dmain PF10520.9 KND86291.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain DUF87 PF01935.17 KND86291.1 - 0.089 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 KND86291.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND86292.1 - 1.1e-08 35.7 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 KND86292.1 - 0.0024 17.0 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KND86292.1 - 0.0061 16.3 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KND86292.1 - 0.0069 16.8 0.1 0.06 13.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KND86292.1 - 0.015 15.1 0.1 0.015 15.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KND86292.1 - 0.017 15.1 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KND86292.1 - 0.019 14.4 0.2 0.04 13.3 0.2 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND86292.1 - 0.024 14.9 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KND86292.1 - 0.025 14.6 0.3 0.046 13.8 0.3 1.4 1 0 0 1 1 1 0 Dynamin family ATPase_2 PF01637.18 KND86292.1 - 0.043 13.7 0.0 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 KND86292.1 - 0.048 14.1 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KND86292.1 - 0.084 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KND86292.1 - 0.097 12.8 0.2 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 KND86292.1 - 0.11 11.3 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.12 KND86292.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KND86292.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PALP PF00291.25 KND86294.1 - 9.2e-42 143.4 0.3 1e-41 143.3 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_30 PF13604.6 KND86295.1 - 9.9e-10 38.4 0.3 1.5e-09 37.8 0.3 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 KND86295.1 - 2.4e-08 33.6 1.5 7.5e-08 31.9 1.5 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 KND86295.1 - 2.1e-07 31.4 0.5 1.3e-06 28.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KND86295.1 - 3.4e-05 23.8 0.1 7.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Helicase AAA_5 PF07728.14 KND86295.1 - 0.046 13.7 0.3 0.18 11.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) EphA2_TM PF14575.6 KND86297.1 - 0.071 14.0 0.0 0.15 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CFEM PF05730.11 KND86297.1 - 3 8.0 26.0 0.36 11.0 3.3 3.5 3 1 0 3 3 3 0 CFEM domain Glyco_hydro_71 PF03659.14 KND86300.1 - 2e-79 267.1 4.1 2.4e-79 266.9 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_3 PF00933.21 KND86301.1 - 9.8e-84 281.4 0.0 1.3e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KND86301.1 - 0.0047 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Abhydrolase_1 PF00561.20 KND86302.1 - 3.9e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND86302.1 - 0.0061 17.2 0.0 0.0079 16.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidase PF01425.21 KND86303.1 - 3.9e-67 227.2 1.1 8.6e-66 222.7 0.2 2.0 2 0 0 2 2 2 2 Amidase F-box_4 PF15966.5 KND86304.1 - 0.11 12.4 3.6 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 F-box CDC24_OB2 PF17245.2 KND86304.1 - 0.11 13.1 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 Fungal_trans_2 PF11951.8 KND86305.1 - 2.3e-23 82.7 0.0 2.9e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86305.1 - 0.00063 19.8 11.2 0.00063 19.8 11.2 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DCD PF06559.11 KND86306.1 - 0.0082 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) ATPase-cat_bd PF12156.8 KND86307.1 - 0.1 13.4 0.0 22 5.9 0.0 2.4 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase APH PF01636.23 KND86308.1 - 6.8e-09 36.0 0.0 1.8e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86308.1 - 0.0078 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KND86308.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KND86308.1 - 0.017 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Anoctamin PF04547.12 KND86309.1 - 3.7e-98 329.3 7.0 4.9e-98 328.9 7.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel APH PF01636.23 KND86310.1 - 4.3e-06 26.8 0.0 0.0003 20.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND86310.1 - 2.7e-05 23.6 0.0 0.00016 21.1 0.0 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KND86310.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KND86310.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KND86310.1 - 0.003 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KND86310.1 - 0.037 13.6 0.1 1.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase Glyco_hydro_18 PF00704.28 KND86311.1 - 5e-39 134.9 2.1 1e-38 133.9 2.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KND86311.1 - 1.4e-12 47.5 1.2 5e-07 29.7 0.0 3.9 4 0 0 4 4 4 2 LysM domain Chitin_bind_1 PF00187.19 KND86311.1 - 5.2e-07 30.0 8.5 5.2e-07 30.0 8.5 2.8 2 0 0 2 2 2 1 Chitin recognition protein DZR PF12773.7 KND86313.1 - 0.0093 16.0 4.1 0.019 15.0 4.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KND86313.1 - 0.073 12.8 6.3 0.13 12.0 6.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KND86313.1 - 2.5 7.6 9.1 4.5 6.8 9.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MFS_1 PF07690.16 KND86314.1 - 5.3e-18 65.1 73.8 4.1e-14 52.3 43.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KND86314.1 - 0.0013 18.1 24.6 0.0013 18.1 24.6 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Methyltransf_3 PF01596.17 KND86315.1 - 1.1e-24 86.8 0.0 1.4e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KND86315.1 - 2.5e-11 44.6 0.1 5.2e-11 43.5 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86315.1 - 2.1e-05 25.2 0.0 3.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND86315.1 - 0.00023 21.7 0.0 0.00043 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 KND86315.1 - 0.004 16.7 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KND86315.1 - 0.0043 16.8 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 KND86315.1 - 0.0084 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Peptidase_S49 PF01343.18 KND86315.1 - 0.041 13.8 0.1 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 MFS_1 PF07690.16 KND86316.1 - 2e-41 142.1 53.3 2.9e-21 75.8 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SVM_signal PF12113.8 KND86316.1 - 0.35 10.8 7.8 0.31 11.0 0.6 2.7 2 0 0 2 2 2 0 SVM protein signal sequence MFS_1 PF07690.16 KND86317.1 - 4.9e-39 134.3 51.6 1.3e-38 132.8 49.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF202 PF02656.15 KND86317.1 - 0.014 15.8 2.4 0.014 15.8 2.4 5.9 6 2 1 7 7 6 0 Domain of unknown function (DUF202) DUF5362 PF17319.2 KND86317.1 - 0.71 9.8 5.7 0.45 10.4 0.3 3.4 3 1 1 4 4 4 0 Family of unknown function (DUF5362) CUE PF02845.16 KND86318.1 - 7.8e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain HMD PF03201.16 KND86319.1 - 0.0087 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CUT PF02376.15 KND86319.1 - 0.14 12.3 0.0 8 6.7 0.0 2.6 2 0 0 2 2 2 0 CUT domain Ofd1_CTDD PF10637.9 KND86320.1 - 1.6e-98 329.1 0.0 3.5e-92 308.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KND86320.1 - 1e-26 93.4 0.0 6.6e-26 90.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KND86320.1 - 2.9e-13 50.5 0.0 5.6e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PMT PF02366.18 KND86321.1 - 9.3e-82 274.3 14.7 1.4e-81 273.7 14.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND86321.1 - 1.5e-69 233.6 5.1 1.5e-69 233.6 5.1 2.6 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND86321.1 - 9.1e-24 84.3 2.5 2.4e-23 83.0 1.2 2.0 1 1 1 2 2 2 2 MIR domain CAP59_mtransfer PF11735.8 KND86322.1 - 4.6e-88 295.0 0.0 5.7e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-H2C2_5 PF13909.6 KND86324.1 - 0.0045 16.7 4.7 0.033 13.9 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 KND86324.1 - 1.2 9.7 13.3 0.072 13.6 1.6 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Sina PF03145.16 KND86324.1 - 8.6 6.2 6.8 15 5.4 6.8 1.4 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 KND86324.1 - 8.8 7.5 14.0 1.8 9.6 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger PHD PF00628.29 KND86325.1 - 5.4e-08 32.6 9.9 8.8e-08 31.9 9.9 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KND86325.1 - 0.00022 21.1 2.9 0.00022 21.1 2.9 1.6 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 KND86325.1 - 0.017 14.8 3.7 0.043 13.4 3.7 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain SRRM_C PF15230.6 KND86325.1 - 0.033 14.8 1.5 0.1 13.2 1.5 1.8 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus PHD20L1_u1 PF16660.5 KND86325.1 - 0.056 14.2 2.2 0.082 13.7 0.6 2.0 1 1 0 1 1 1 0 PHD finger protein 20-like protein 1 FYVE_2 PF02318.16 KND86325.1 - 0.11 12.8 4.8 0.19 12.0 4.8 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger PHD_4 PF16866.5 KND86325.1 - 0.15 12.2 6.4 0.38 10.9 6.4 1.7 1 0 0 1 1 1 0 PHD-finger DNA_RNApol_7kD PF03604.13 KND86325.1 - 0.29 10.8 6.7 0.71 9.6 1.4 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Zf_RING PF16744.5 KND86325.1 - 0.52 10.5 5.6 2.3 8.4 5.6 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger UL42 PF17638.2 KND86325.1 - 0.82 9.6 4.3 2 8.4 4.3 1.6 1 0 0 1 1 1 0 HCMV UL42 cEGF PF12662.7 KND86326.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.6 2 0 0 2 2 2 0 Complement Clr-like EGF-like DUF3194 PF11419.8 KND86326.1 - 0.7 10.3 7.2 14 6.1 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3194) Lipoprotein_19 PF13617.6 KND86326.1 - 3.5 7.5 6.5 0.77 9.6 0.7 2.9 4 0 0 4 4 4 0 YnbE-like lipoprotein Asn_synthase PF00733.21 KND86327.1 - 2e-14 54.0 1.1 2.4e-05 24.2 0.1 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KND86327.1 - 1.3e-06 28.3 0.0 7.5e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain Lipase_GDSL_2 PF13472.6 KND86328.1 - 2e-17 64.2 0.1 2.7e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND86328.1 - 4.5e-11 43.1 0.0 5.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KND86328.1 - 8.1e-05 22.8 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TFIIB PF00382.19 KND86329.1 - 1.4e-33 114.8 0.4 1e-19 70.3 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KND86329.1 - 2.4e-12 46.1 3.4 5.3e-11 41.9 3.2 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 KND86329.1 - 0.0018 18.3 0.2 0.0049 16.9 0.1 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 KND86329.1 - 0.017 15.2 0.0 12 6.1 0.0 2.7 2 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.6 KND86329.1 - 0.021 14.2 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.23 KND86329.1 - 0.058 13.1 1.0 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain Glycos_transf_3 PF00591.21 KND86330.1 - 5.8e-60 203.0 0.0 1.2e-59 202.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KND86330.1 - 4.7e-14 52.0 0.2 1.1e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain MLANA PF14991.6 KND86331.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein melan-A Phosducin PF02114.16 KND86331.1 - 0.21 10.5 0.2 4.3 6.2 0.1 2.0 1 1 1 2 2 2 0 Phosducin CoA_transf_3 PF02515.17 KND86332.1 - 4.6e-128 427.4 0.0 5.3e-128 427.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PhoLip_ATPase_C PF16212.5 KND86333.1 - 6.7e-66 222.6 17.2 6.7e-66 222.6 17.2 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND86333.1 - 6.5e-24 83.4 0.7 1.2e-22 79.4 0.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KND86333.1 - 3.8e-12 46.9 0.5 2.8e-07 31.0 0.0 3.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND86333.1 - 7.6e-07 29.1 0.0 7.9e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KND86333.1 - 5.1e-06 26.1 0.3 6.6e-05 22.5 0.3 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND86333.1 - 0.041 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KND86333.1 - 0.13 12.4 0.0 0.45 10.6 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Asparaginase PF00710.20 KND86334.1 - 1.5e-50 171.4 0.0 2e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KND86334.1 - 1.8e-19 70.0 0.0 6.3e-19 68.3 0.0 1.9 2 1 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Methyltransf_16 PF10294.9 KND86335.1 - 1e-43 149.1 0.0 1.3e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 KND86335.1 - 0.00046 20.0 0.0 0.00082 19.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KND86335.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 KND86335.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KND86335.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KND86335.1 - 0.096 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2947 PF11163.8 KND86335.1 - 0.18 11.6 0.2 0.26 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Peptidase_M24 PF00557.24 KND86336.1 - 8.7e-44 149.7 0.1 1.3e-43 149.2 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 KND86336.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase AA_permease PF00324.21 KND86337.1 - 4.9e-58 196.9 12.4 6.1e-58 196.6 12.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND86337.1 - 3.9e-18 65.5 12.3 5.4e-18 65.0 12.2 1.2 1 1 0 1 1 1 1 Amino acid permease Spore_YhaL PF14147.6 KND86337.1 - 0.43 10.3 0.1 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL AhpC-TSA_2 PF13911.6 KND86338.1 - 4.6e-17 62.2 0.0 1.7e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KND86338.1 - 2.3e-05 24.3 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND86338.1 - 0.00049 19.8 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF1772 PF08592.11 KND86342.1 - 0.85 9.9 6.1 10 6.4 0.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) Aldo_ket_red PF00248.21 KND86343.1 - 4.1e-50 170.6 0.0 4.8e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATG7_N PF16420.5 KND86344.1 - 2.9e-110 368.6 0.0 3.6e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KND86344.1 - 2e-45 155.1 0.0 2.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family PIG-F PF06699.11 KND86345.1 - 9.3e-54 182.3 2.7 1.3e-53 181.9 2.7 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.6 KND86345.1 - 0.38 10.5 4.1 1.2 9.0 4.1 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KND86345.1 - 3.5 7.7 9.8 0.35 10.9 4.7 1.9 2 0 0 2 2 2 0 Glycine zipper Pmp3 PF01679.17 KND86346.1 - 3.3e-20 72.0 7.8 4.6e-20 71.5 7.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SNF2_N PF00176.23 KND86347.1 - 3.7e-47 160.7 0.2 6.7e-47 159.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KND86347.1 - 1.3e-26 92.5 0.4 1.3e-26 92.5 0.4 2.5 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KND86347.1 - 4e-19 69.0 0.0 1.4e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KND86347.1 - 1e-07 31.4 0.1 2.4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KND86347.1 - 4.1e-07 30.2 0.2 3.8e-06 27.0 0.0 2.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND86347.1 - 0.00078 19.2 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KND86347.1 - 0.11 11.3 0.4 3.9 6.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 SNF2_N PF00176.23 KND86348.1 - 3e-47 161.0 0.2 5.5e-47 160.2 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 KND86348.1 - 1.1e-26 92.7 0.4 1.1e-26 92.7 0.4 2.5 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 KND86348.1 - 3.2e-19 69.3 0.0 1.2e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KND86348.1 - 8.7e-08 31.7 0.1 2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KND86348.1 - 2.9e-07 30.7 0.1 3.2e-06 27.3 0.0 2.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND86348.1 - 0.00064 19.5 0.0 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KND86348.1 - 0.087 11.7 0.4 3.4 6.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Methyltransf_23 PF13489.6 KND86349.1 - 8.2e-12 45.3 0.0 1.2e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND86349.1 - 2.1e-07 31.6 0.0 1.2e-06 29.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND86349.1 - 1.4e-06 28.9 0.0 3.5e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86349.1 - 9.7e-06 26.2 0.0 0.00016 22.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND86349.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KND86349.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KND86349.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_31 PF13847.6 KND86349.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain S4 PF01479.25 KND86350.1 - 4.9e-12 45.4 0.0 1.5e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 KND86350.1 - 4.4e-10 40.3 1.0 7.2e-10 39.6 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 KND86350.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PPR_3 PF13812.6 KND86351.1 - 2.6e-06 27.4 0.0 0.0048 16.9 0.0 3.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 KND86351.1 - 2.1e-05 24.6 0.0 26 5.1 0.0 5.5 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.20 KND86351.1 - 0.12 12.7 6.8 3.5 8.1 0.0 4.8 6 0 0 6 6 6 0 PPR repeat Ribosomal_S18 PF01084.20 KND86352.1 - 2.5e-09 37.2 0.0 4.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 KND86353.1 - 3.2e-08 33.6 0.0 0.022 14.9 0.1 3.1 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 KND86353.1 - 5.7e-05 23.1 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KND86353.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 PPR repeat He_PIG PF05345.12 KND86354.1 - 5e-12 45.8 14.0 0.00082 19.5 0.0 4.7 4 0 0 4 4 4 3 Putative Ig domain TMEM154 PF15102.6 KND86354.1 - 3.5e-05 23.7 0.2 9.1e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family Endomucin PF07010.12 KND86354.1 - 0.0023 18.0 1.2 0.0023 18.0 1.2 2.0 3 0 0 3 3 3 1 Endomucin DUF4448 PF14610.6 KND86354.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 KND86354.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) PP2C PF00481.21 KND86355.1 - 6.2e-79 265.3 0.0 1e-78 264.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DHDPS PF00701.22 KND86356.1 - 3.4e-25 88.3 0.0 4.5e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GHMP_kinases_N PF00288.26 KND86357.1 - 1.7e-09 37.7 0.0 3.4e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND86357.1 - 2.9e-05 24.3 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal CFEM PF05730.11 KND86358.1 - 5.1e-10 39.3 6.7 8.8e-10 38.5 6.7 1.4 1 0 0 1 1 1 1 CFEM domain 4HBT_2 PF13279.6 KND86359.1 - 0.00019 21.9 0.0 0.00034 21.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily EamA PF00892.20 KND86361.1 - 1.2e-12 48.1 24.6 2.3e-06 27.8 13.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 KND86361.1 - 6.4e-07 28.7 8.8 1.5e-06 27.4 8.8 1.6 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 KND86361.1 - 2.3 7.3 9.8 0.42 9.7 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter Cerato-platanin PF07249.12 KND86362.1 - 3.2e-53 178.9 0.3 3.7e-53 178.7 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin WD40 PF00400.32 KND86365.1 - 3.7e-15 56.0 12.1 0.0014 19.4 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND86365.1 - 0.00028 21.1 0.0 0.076 13.3 0.0 4.0 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND86365.1 - 0.00075 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 KND86365.1 - 0.0024 16.9 0.4 1.2 8.1 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein dCMP_cyt_deam_1 PF00383.23 KND86366.1 - 2.6e-25 88.2 1.7 3.9e-25 87.7 1.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KND86366.1 - 3.4e-09 36.6 0.2 6e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KND86366.1 - 5e-05 23.8 0.0 0.013 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain CoaE PF01121.20 KND86366.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 KND86366.1 - 0.017 15.5 1.4 0.13 12.7 0.3 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KND86366.1 - 0.035 14.3 0.5 0.15 12.3 0.5 2.0 1 1 0 1 1 1 0 AAA domain Met_synt_B12 PF02965.17 KND86366.1 - 0.26 10.7 0.0 0.66 9.4 0.0 1.6 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Pkinase PF00069.25 KND86367.1 - 4e-40 137.9 0.0 4.8e-37 127.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND86367.1 - 4.8e-22 78.5 0.0 7.7e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DAO PF01266.24 KND86368.1 - 4.9e-50 171.1 1.0 5.8e-50 170.8 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND86368.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND86368.1 - 5.3e-05 23.4 0.1 0.00012 22.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND86368.1 - 7.2e-05 22.2 0.0 0.03 13.6 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND86368.1 - 0.0001 21.6 0.0 0.00025 20.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND86368.1 - 0.00022 20.6 0.3 0.00043 19.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KND86368.1 - 0.00025 20.5 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND86368.1 - 0.00029 19.6 0.4 0.025 13.3 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KND86368.1 - 0.0018 17.6 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KND86368.1 - 0.011 15.0 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KND86368.1 - 0.062 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 KND86368.1 - 0.076 12.3 0.7 4.3 6.5 0.2 2.5 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KND86368.1 - 0.095 12.7 1.2 11 6.0 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KND86368.1 - 0.16 12.5 0.3 0.53 10.9 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KND86368.1 - 0.27 10.3 0.3 0.38 9.8 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Kelch_3 PF13415.6 KND86370.1 - 1.1e-24 86.2 12.7 4.9e-06 26.7 0.2 7.7 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KND86370.1 - 3.1e-20 71.7 2.1 1.2e-08 35.0 0.0 5.2 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KND86370.1 - 1.4e-16 59.8 1.6 8.6e-08 31.6 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 KND86370.1 - 2.8e-16 59.2 20.3 1.2e-05 25.2 0.0 7.5 8 1 1 9 9 9 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KND86370.1 - 1.3e-13 50.4 7.9 4.7e-06 26.4 0.5 5.9 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KND86370.1 - 2.9e-13 49.5 9.2 7.9e-06 25.7 0.0 6.9 8 0 0 8 8 8 2 Kelch motif 2Fe-2S_thioredx PF01257.19 KND86371.1 - 3.8e-58 195.5 0.0 4.6e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin CorA PF01544.18 KND86372.1 - 0.00049 19.5 3.2 0.0012 18.2 3.2 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srv PF10323.9 KND86372.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Stevor PF17410.2 KND86372.1 - 0.02 14.5 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF2681 PF10883.8 KND86372.1 - 0.026 14.9 0.2 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Cep57_CLD PF14073.6 KND86372.1 - 0.029 14.4 0.1 0.068 13.2 0.1 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 SRTM1 PF15872.5 KND86372.1 - 0.099 12.8 0.0 0.79 9.9 0.0 2.4 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 PspB PF06667.12 KND86372.1 - 0.61 10.2 3.3 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Phage shock protein B DUF1712 PF08217.11 KND86373.1 - 1.4e-13 50.2 0.0 2.7e-12 46.0 0.0 2.5 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) CCDC53 PF10152.9 KND86373.1 - 3.1 8.2 5.9 0.83 10.1 0.3 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Herpes_gE PF02480.16 KND86374.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4690 PF15756.5 KND86374.1 - 0.085 13.5 0.1 0.33 11.6 0.1 2.0 1 0 0 1 1 1 0 Small Novel Rich in Cartilage SKG6 PF08693.10 KND86374.1 - 0.31 10.5 2.8 0.66 9.4 2.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DPBB_1 PF03330.18 KND86375.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase PRCC PF10253.9 KND86375.1 - 7.1 7.4 9.7 12 6.7 9.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ABC_membrane PF00664.23 KND86377.1 - 3.1e-79 266.5 38.1 2.6e-41 142.1 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND86377.1 - 4.6e-59 198.8 0.1 7.5e-29 101.0 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND86377.1 - 2.2e-14 53.5 8.4 7.3e-07 28.8 1.6 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND86377.1 - 7.4e-08 32.8 0.4 0.072 13.4 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KND86377.1 - 9.2e-08 32.6 0.1 0.067 13.6 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND86377.1 - 6.4e-07 29.4 0.1 0.006 16.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KND86377.1 - 1e-06 28.4 2.1 0.0011 18.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KND86377.1 - 5.9e-06 25.3 0.6 0.38 9.5 0.0 3.4 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 KND86377.1 - 8.3e-06 25.7 0.6 0.035 13.8 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KND86377.1 - 3.4e-05 23.7 0.7 0.14 11.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 KND86377.1 - 4.2e-05 23.5 0.4 0.43 10.3 0.1 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KND86377.1 - 4.3e-05 23.2 0.4 0.37 10.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KND86377.1 - 0.00018 21.9 4.0 2.8 8.4 0.1 4.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 KND86377.1 - 0.00024 20.8 0.0 0.85 9.2 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 KND86377.1 - 0.0004 20.4 0.5 0.2 11.7 0.1 3.5 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 KND86377.1 - 0.0012 19.4 0.1 2.7 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KND86377.1 - 0.0012 19.0 2.1 2.7 8.3 0.2 4.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KND86377.1 - 0.0028 17.2 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 KND86377.1 - 0.003 18.1 6.5 0.037 14.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KND86377.1 - 0.0076 16.2 0.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 KND86377.1 - 0.0084 16.1 0.1 9.2 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 KND86377.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PRK PF00485.18 KND86377.1 - 0.032 14.0 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 KND86377.1 - 0.034 14.3 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KND86377.1 - 0.035 14.4 0.1 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND86377.1 - 0.065 12.5 0.0 8.4 5.6 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 KND86377.1 - 0.071 12.8 0.4 13 5.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KND86377.1 - 0.078 12.2 0.2 5.2 6.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.12 KND86377.1 - 0.1 12.5 0.1 21 5.0 0.0 2.7 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 KND86377.1 - 0.21 10.7 0.0 18 4.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PP-binding PF00550.25 KND86378.1 - 7.5e-12 45.4 0.1 1.4e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KND86378.1 - 1.2e-05 25.4 0.6 1.9e-05 24.8 0.6 1.4 1 1 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 KND86379.1 - 2.1e-07 30.7 9.5 5e-06 26.3 1.9 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND86379.1 - 4.3e-07 29.8 17.1 6.3e-06 26.1 3.4 3.1 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 KND86379.1 - 7.4e-06 26.6 2.7 0.0014 19.3 0.5 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KND86379.1 - 9.4e-06 25.3 11.9 0.0014 18.3 0.9 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KND86379.1 - 0.00066 19.9 0.3 0.0013 18.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KND86379.1 - 0.7 10.5 17.7 0.21 12.1 2.8 3.0 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Peptidase_M14 PF00246.24 KND86380.1 - 1.8e-34 119.9 0.1 2.3e-34 119.6 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 KND86380.1 - 0.17 10.9 0.0 2.5 7.1 0.0 2.7 2 1 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family Fer4 PF00037.27 KND86381.1 - 2.9e-13 49.0 16.5 8.8e-08 31.7 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KND86381.1 - 1e-12 48.4 10.2 2.5e-12 47.2 10.2 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KND86381.1 - 4.7e-10 40.2 7.4 0.00013 22.9 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KND86381.1 - 8.7e-09 35.4 31.2 8.4e-06 25.8 12.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 KND86381.1 - 4.7e-08 33.0 21.2 4.2e-06 26.8 12.2 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KND86381.1 - 5.1e-08 33.0 9.9 1.3e-07 31.7 9.9 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KND86381.1 - 2e-06 28.1 19.4 0.00022 21.6 11.1 2.9 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 KND86381.1 - 2.1e-06 27.5 17.1 0.00056 19.9 5.4 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KND86381.1 - 6.3e-06 26.0 11.8 0.014 15.5 1.7 2.7 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KND86381.1 - 0.00048 20.6 11.4 0.09 13.3 12.8 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 KND86381.1 - 0.00051 20.3 2.0 0.00051 20.3 2.0 2.8 3 0 0 3 3 2 2 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.10 KND86381.1 - 0.0082 16.3 5.2 0.84 9.9 0.4 2.4 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 KND86381.1 - 0.025 15.1 12.9 1 9.9 4.3 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 KND86381.1 - 0.085 13.0 5.0 0.3 11.3 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_18 PF13746.6 KND86381.1 - 0.14 12.4 8.8 1.7 8.8 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KND86381.1 - 0.32 12.1 15.5 0.59 11.2 3.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KND86381.1 - 5.4 7.9 14.3 4.1 8.3 1.7 2.7 2 1 1 3 3 2 0 4Fe-4S dicluster domain Ank_2 PF12796.7 KND86383.1 - 4.8e-16 59.1 0.0 8.3e-06 26.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND86383.1 - 9.3e-15 54.5 2.9 4.6e-07 30.0 0.2 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86383.1 - 2.5e-14 52.0 0.2 0.0054 17.1 0.0 6.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 KND86383.1 - 5.8e-11 42.7 0.4 8.7e-05 23.0 0.0 3.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KND86383.1 - 1e-09 38.4 0.1 0.027 14.9 0.0 5.4 4 2 0 4 4 4 3 Ankyrin repeat Fungal_trans PF04082.18 KND86384.1 - 3.3e-17 62.4 0.0 5.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86384.1 - 1.2e-09 38.1 10.1 2.6e-09 37.0 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HGTP_anticodon PF03129.20 KND86385.1 - 1.9e-20 72.8 0.0 1.1e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KND86385.1 - 5.2e-09 36.3 0.0 8.1e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Fructosamin_kin PF03881.14 KND86389.1 - 4.8e-22 78.5 0.4 6e-22 78.2 0.4 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KND86390.1 - 4e-09 36.8 0.2 5.6e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86390.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KND86390.1 - 0.11 11.8 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain DUF3632 PF12311.8 KND86391.1 - 1.6e-39 136.2 0.4 2e-39 135.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Helicase_C_2 PF13307.6 KND86392.1 - 4.4e-60 202.8 0.0 8.4e-60 201.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KND86392.1 - 3.6e-32 111.4 0.0 6.3e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 KND86392.1 - 0.014 15.4 0.0 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KND86392.1 - 0.072 12.9 0.0 0.5 10.1 0.0 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase GRIM-19 PF06212.12 KND86395.1 - 0.00077 19.4 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 GRIM-19 protein NIF PF03031.18 KND86396.1 - 1.6e-26 93.0 0.0 3.2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 KND86396.1 - 2.4e-09 37.4 0.0 6.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KND86396.1 - 8.8e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 KND86396.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 KND86396.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KND86396.1 - 0.01 15.9 0.2 0.028 14.5 0.2 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KND86396.1 - 0.026 14.8 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Biotin_lipoyl PF00364.22 KND86396.1 - 0.033 14.0 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme Ribosomal_S2 PF00318.20 KND86396.1 - 0.039 13.2 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S2 Cnd1_N PF12922.7 KND86397.1 - 1.2e-63 213.9 0.1 2.1e-62 209.8 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KND86397.1 - 9.6e-49 165.5 1.8 3.5e-44 150.7 0.1 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KND86397.1 - 1.5e-10 40.4 3.0 0.047 14.0 0.1 5.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 KND86397.1 - 1.3e-09 38.3 2.9 0.00015 22.1 0.1 4.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KND86397.1 - 7.5e-06 26.3 4.3 0.14 12.7 0.1 5.4 4 0 0 4 4 4 1 HEAT-like repeat RTP1_C1 PF10363.9 KND86397.1 - 8.3e-05 22.7 0.0 0.087 13.0 0.0 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KND86397.1 - 0.00014 20.6 4.4 0.023 13.3 0.1 3.4 3 1 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 KND86397.1 - 0.0024 17.1 6.9 0.008 15.4 0.9 3.4 2 2 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain MIEAP PF16026.5 KND86397.1 - 0.021 15.0 0.7 0.18 12.0 0.0 2.8 3 1 0 3 3 3 0 Mitochondria-eating protein Ald_Xan_dh_C2 PF02738.18 KND86397.1 - 0.063 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase Pkinase PF00069.25 KND86398.1 - 1.7e-41 142.3 0.0 1.1e-18 67.6 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KND86398.1 - 1.2e-15 57.5 0.0 3e-09 36.5 0.0 3.9 3 1 1 4 4 4 2 Protein tyrosine kinase APH PF01636.23 KND86398.1 - 0.00027 20.9 5.5 0.019 14.9 5.1 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KND86398.1 - 0.0032 17.1 3.6 0.11 12.1 2.9 2.9 2 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KND86398.1 - 0.007 15.7 0.2 0.57 9.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 KND86398.1 - 0.011 14.6 0.0 0.011 14.6 0.0 2.5 2 1 0 2 2 2 0 Fungal protein kinase TERB2 PF15101.6 KND86398.1 - 0.14 12.2 14.3 0.24 11.4 1.7 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 BUD22 PF09073.10 KND86398.1 - 0.35 10.2 18.4 0.54 9.6 18.4 1.2 1 0 0 1 1 1 0 BUD22 Connexin PF00029.19 KND86398.1 - 6.2 6.5 11.2 1.9 8.2 0.6 2.2 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 KND86398.1 - 9.9 5.9 19.4 9.8 5.9 10.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ribosomal_L27A PF00828.19 KND86399.1 - 4.4e-21 75.9 0.0 7e-21 75.2 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Transp_cyt_pur PF02133.15 KND86400.1 - 7.9e-34 117.2 30.3 1.9e-33 115.9 30.3 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin bZIP_2 PF07716.15 KND86400.1 - 0.00011 22.3 8.5 0.00025 21.1 8.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KND86400.1 - 0.00069 19.7 5.8 0.00069 19.7 5.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor DUF2517 PF10725.9 KND86400.1 - 0.11 12.3 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Macoilin PF09726.9 KND86400.1 - 1.7 7.1 4.1 2.8 6.4 4.1 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 KND86401.1 - 9.7e-19 67.8 0.0 3.2e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86401.1 - 1.7e-12 47.2 0.0 1e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND86401.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3632 PF12311.8 KND86402.1 - 1.4e-21 77.7 0.0 2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ig_3 PF13927.6 KND86403.1 - 0.051 14.2 4.7 0.84 10.3 0.2 3.2 3 1 0 3 3 3 0 Immunoglobulin domain Glyco_hydro_114 PF03537.13 KND86404.1 - 4.4e-83 278.1 0.0 5.2e-83 277.9 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF3693 PF12472.8 KND86404.1 - 0.038 13.7 0.7 0.076 12.7 0.7 1.4 1 0 0 1 1 1 0 Phage related protein Gln-synt_C PF00120.24 KND86405.1 - 3.6e-69 233.4 0.0 5.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 KND86405.1 - 4.4e-15 56.2 0.1 1.3e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Gln-synt_N_2 PF16952.5 KND86405.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain LEH PF07858.12 KND86405.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Glyco_hydro_49N PF17433.2 KND86406.1 - 5.7e-59 198.9 3.9 1.4e-58 197.6 3.9 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain IPU_b_solenoid PF18783.1 KND86406.1 - 1.2e-20 73.3 3.1 1.2e-20 73.3 3.1 2.1 2 0 0 2 2 2 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 KND86406.1 - 1.7e-19 69.8 4.1 4.7e-19 68.4 4.1 1.8 1 0 0 1 1 1 1 Beta solenoid repeat from Dextranase Glyco_hydro_49 PF03718.13 KND86406.1 - 3.1e-19 69.1 0.1 8.6e-19 67.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 NAD_binding_4 PF07993.12 KND86407.1 - 3.5e-26 91.9 0.0 5.8e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KND86407.1 - 7.4e-23 80.8 0.0 3.4e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KND86407.1 - 2.1e-11 43.8 0.0 3.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KND86407.1 - 3.2e-05 24.2 0.0 9.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KND86407.1 - 0.0048 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KND86407.1 - 0.18 11.7 0.6 0.53 10.2 0.1 2.1 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KND86407.1 - 0.25 10.4 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KND86408.1 - 1.9e-11 43.5 8.1 3.4e-11 42.7 8.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86408.1 - 6.5e-07 28.6 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1030 PF06270.11 KND86408.1 - 2.5 7.9 5.7 0.91 9.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1030) Helitron_like_N PF14214.6 KND86411.1 - 4.4e-29 102.0 0.4 4.4e-29 102.0 0.4 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Utp12 PF04003.12 KND86411.1 - 0.035 14.4 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Dip2/Utp12 Family zf-TFIIB PF13453.6 KND86411.1 - 1.2 8.5 4.2 3.3 7.1 4.2 1.9 1 1 0 1 1 1 0 Transcription factor zinc-finger DUF3819 PF12842.7 KND86412.1 - 2.2e-05 24.4 0.2 0.0035 17.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3819) NUC129 PF08157.11 KND86412.1 - 0.16 12.4 0.2 0.53 10.7 0.1 1.8 2 0 0 2 2 2 0 NUC129 domain APH PF01636.23 KND86414.1 - 6.1e-15 55.8 0.0 1.4e-14 54.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86414.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND86414.1 - 0.0047 16.5 0.1 0.67 9.5 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 KND86414.1 - 0.044 13.1 0.0 5.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain HSP20 PF00011.21 KND86415.1 - 3.4e-16 59.2 0.0 5e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KND86415.1 - 5.5e-07 29.0 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 2 HSP20-like domain found in ArsA NYN PF01936.18 KND86417.1 - 1.2e-30 107.0 0.0 1.7e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 KND86417.1 - 4.3e-09 36.1 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN7 PF18475.1 KND86417.1 - 0.011 16.3 0.0 0.067 13.8 0.0 2.2 2 1 0 2 2 2 0 PIN domain Dynamin_N PF00350.23 KND86418.1 - 8.7e-34 117.0 0.0 1.8e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND86418.1 - 2.1e-21 76.4 0.3 6e-18 65.1 0.0 2.7 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.23 KND86418.1 - 4.8e-05 23.4 0.1 0.0086 16.2 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase DPPIV_rep PF18811.1 KND86418.1 - 0.019 14.9 0.2 0.049 13.6 0.2 1.7 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) low complexity region FeoB_N PF02421.18 KND86418.1 - 0.043 13.3 0.2 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B GED PF02212.18 KND86418.1 - 0.11 12.6 0.5 0.62 10.2 0.1 2.6 2 1 0 2 2 2 0 Dynamin GTPase effector domain K_oxygenase PF13434.6 KND86419.1 - 9.1e-12 44.8 0.7 3.1e-08 33.1 0.0 3.4 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KND86419.1 - 1.1e-08 35.1 0.1 6.9e-07 29.2 0.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.19 KND86419.1 - 1.2e-08 33.9 0.7 2.3e-07 29.6 0.3 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KND86419.1 - 4.8e-08 33.1 0.0 1.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND86419.1 - 2.5e-07 30.3 0.0 8.3e-06 25.3 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND86419.1 - 5e-07 29.2 0.0 0.0013 18.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND86419.1 - 7e-06 26.1 0.1 0.023 14.7 0.0 3.2 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KND86419.1 - 0.00063 19.1 0.0 0.014 14.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KND86419.1 - 0.033 13.2 0.0 0.08 12.0 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KND86419.1 - 0.066 11.9 0.0 0.44 9.2 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KND86419.1 - 0.067 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KND86419.1 - 0.075 13.1 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KND86419.1 - 0.081 12.2 0.0 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KND86419.1 - 0.099 11.9 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DPBB_1 PF03330.18 KND86420.1 - 0.15 12.3 0.3 0.5 10.7 0.1 1.9 2 0 0 2 2 2 0 Lytic transglycolase adh_short_C2 PF13561.6 KND86421.1 - 1.6e-59 201.3 0.5 2.8e-59 200.5 0.5 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND86421.1 - 3.3e-50 170.3 0.5 6.1e-50 169.4 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Zn_clus PF00172.18 KND86421.1 - 2.6e-08 33.8 9.8 4.9e-08 33.0 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND86421.1 - 1.6e-07 30.5 0.6 7.1e-07 28.4 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 KND86421.1 - 1.2e-06 28.6 0.2 5e-06 26.5 0.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND86421.1 - 0.06 12.8 0.2 0.35 10.3 0.2 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Holin_2-3 PF13272.6 KND86421.1 - 0.1 12.9 0.1 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Putative 2/3 transmembrane domain holin Pkinase PF00069.25 KND86423.1 - 1.3e-11 44.4 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86423.1 - 2.2e-05 23.9 0.1 4.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KND86423.1 - 0.007 15.5 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KND86423.1 - 0.051 12.9 0.3 0.092 12.1 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND86423.1 - 0.084 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KND86423.1 - 0.14 12.0 0.2 0.24 11.3 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4872 PF16169.5 KND86425.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4872) BCS1_N PF08740.11 KND86426.1 - 1.3e-55 188.3 0.5 1.3e-55 188.3 0.5 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KND86426.1 - 3.4e-17 63.1 0.0 3.6e-09 37.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND86426.1 - 0.00026 21.4 0.0 0.0012 19.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KND86426.1 - 0.0011 19.0 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KND86426.1 - 0.0012 18.7 12.7 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KND86426.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KND86426.1 - 0.018 14.2 0.0 0.066 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KND86426.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KND86426.1 - 0.027 13.8 0.0 0.2 10.9 0.0 2.3 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 KND86426.1 - 0.15 12.4 0.0 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Selenoprotein_S PF06936.11 KND86426.1 - 0.3 10.9 17.5 0.57 10.0 17.5 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) Gti1_Pac2 PF09729.9 KND86426.1 - 1.4 9.0 10.1 4.1 7.4 10.1 1.8 1 0 0 1 1 1 0 Gti1/Pac2 family CobT PF06213.12 KND86426.1 - 2.5 7.4 21.9 3.3 7.0 18.4 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4407 PF14362.6 KND86426.1 - 3.1 7.1 13.7 5.8 6.2 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Band_3_cyto PF07565.13 KND86426.1 - 3.3 7.4 8.8 5.5 6.7 8.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.13 KND86426.1 - 3.4 6.6 23.1 6 5.8 23.1 1.4 1 0 0 1 1 1 0 Paf1 DUF3362 PF11842.8 KND86426.1 - 3.6 7.9 11.4 1.1e+02 3.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) SAPS PF04499.15 KND86426.1 - 6.6 5.4 17.6 10 4.7 17.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.8 KND86426.1 - 8.5 5.1 17.6 18 4.1 17.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.9 KND86426.1 - 8.8 5.9 30.4 38 3.8 24.6 3.1 3 0 0 3 3 3 0 DDRGK domain AA_permease_2 PF13520.6 KND86427.1 - 9.6e-66 222.3 39.0 1.2e-65 222.1 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND86427.1 - 2.3e-18 66.0 30.8 2.3e-18 66.0 30.8 2.0 1 1 1 2 2 2 1 Amino acid permease TauD PF02668.16 KND86428.1 - 1.5e-32 113.5 0.0 2.1e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KND86428.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 CsiD APH PF01636.23 KND86429.1 - 1.6e-19 70.8 0.0 2.5e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KND86429.1 - 0.0028 16.9 0.0 0.5 9.5 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase RIO1 PF01163.22 KND86429.1 - 0.0044 16.6 0.0 0.07 12.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KND86429.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase BAAT_C PF08840.11 KND86430.1 - 1.7e-06 28.1 0.0 4.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.11 KND86430.1 - 1.8e-05 23.7 0.0 2.5e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KND86430.1 - 3.4e-05 24.6 0.2 8.2e-05 23.3 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND86430.1 - 7.7e-05 22.3 0.0 0.00039 20.0 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND86430.1 - 0.0002 21.1 0.0 0.22 11.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 KND86430.1 - 0.0021 17.7 0.0 0.0096 15.5 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KND86430.1 - 0.0025 17.4 0.0 0.0099 15.5 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 KND86430.1 - 0.018 13.7 0.0 0.034 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KND86430.1 - 0.035 14.0 0.0 0.062 13.1 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KND86431.1 - 1.5e-43 149.1 0.1 5.4e-43 147.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND86431.1 - 0.0013 17.7 0.0 0.021 13.7 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 KND86432.1 - 4.2e-13 49.2 0.0 6.9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HMG_CoA_synt_C PF08540.10 KND86433.1 - 6.6e-106 354.0 1.0 8.2e-106 353.7 1.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KND86433.1 - 2.3e-94 314.1 0.2 3.6e-94 313.5 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TIL PF01826.17 KND86434.1 - 0.00096 19.4 10.4 0.00096 19.4 10.4 2.2 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain TPPK_C PF12555.8 KND86434.1 - 0.023 14.7 0.2 0.049 13.7 0.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Pex14_N PF04695.13 KND86435.1 - 2e-28 100.0 7.7 2e-28 100.0 7.7 3.8 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HLH PF00010.26 KND86435.1 - 0.00034 20.5 0.5 3.7 7.6 0.1 3.3 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain DUF848 PF05852.11 KND86435.1 - 0.00035 20.7 4.5 0.0015 18.6 4.2 1.9 2 0 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) zf-C4H2 PF10146.9 KND86435.1 - 0.00043 20.7 2.0 0.00043 20.7 2.0 2.1 2 0 0 2 2 2 1 Zinc finger-containing protein CR6_interact PF10147.9 KND86435.1 - 0.0019 17.9 0.3 0.0029 17.3 0.3 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ERM PF00769.19 KND86435.1 - 0.0052 16.6 6.2 0.0076 16.1 6.2 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.11 KND86435.1 - 0.0056 15.6 5.5 0.0084 15.0 5.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein LMBR1 PF04791.16 KND86435.1 - 0.0065 15.4 0.3 0.009 15.0 0.3 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Prominin PF05478.11 KND86435.1 - 0.0078 14.2 1.6 0.01 13.9 1.6 1.1 1 0 0 1 1 1 1 Prominin HsbA PF12296.8 KND86435.1 - 0.011 16.1 0.8 0.041 14.3 0.7 2.0 1 1 0 1 1 1 0 Hydrophobic surface binding protein A DUF3584 PF12128.8 KND86435.1 - 0.012 13.2 10.3 0.016 12.7 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1043 PF06295.12 KND86435.1 - 0.018 15.0 4.4 0.03 14.3 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Golgin_A5 PF09787.9 KND86435.1 - 0.024 14.1 8.5 0.036 13.5 8.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 KND86435.1 - 0.025 13.7 1.2 0.038 13.1 1.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KND86435.1 - 0.037 14.5 2.7 0.057 13.9 2.7 1.3 1 0 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 KND86435.1 - 0.1 12.7 8.2 0.39 10.8 7.9 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 KND86435.1 - 0.12 11.0 5.4 0.18 10.4 5.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4795 PF16043.5 KND86435.1 - 0.14 11.7 6.7 0.25 10.9 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Csm1_N PF18504.1 KND86435.1 - 0.22 11.9 9.9 0.11 12.8 5.2 2.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Ribosomal_S13 PF00416.22 KND86435.1 - 0.24 11.8 1.2 0.58 10.6 1.0 1.7 1 1 0 1 1 1 0 Ribosomal protein S13/S18 TSC22 PF01166.18 KND86435.1 - 0.24 11.7 2.9 8.5 6.8 0.2 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family HMMR_N PF15905.5 KND86435.1 - 0.3 10.5 9.7 0.49 9.8 9.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 KND86435.1 - 0.36 10.9 4.8 0.53 10.4 4.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid PF05761.14 KND86435.1 - 0.4 9.5 5.1 0.71 8.7 5.1 1.3 1 0 0 1 1 1 0 5' nucleotidase family FUSC PF04632.12 KND86435.1 - 0.65 8.5 3.6 0.94 7.9 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sipho_Gp157 PF05565.11 KND86435.1 - 0.95 9.5 9.3 1.6 8.7 9.3 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4407 PF14362.6 KND86435.1 - 1.2 8.5 8.8 1.9 7.8 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 KND86435.1 - 1.2 8.7 7.7 1.7 8.2 7.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) OmpH PF03938.14 KND86435.1 - 1.2 9.4 10.6 2.4 8.5 10.6 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 KND86435.1 - 1.4 9.1 4.5 2.9 8.1 4.5 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 KND86435.1 - 1.4 9.4 9.5 7.2 7.2 7.5 2.2 1 1 0 1 1 1 0 Spectrin repeat FlaC_arch PF05377.11 KND86435.1 - 2.3 8.7 4.7 1.9 8.9 0.2 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 KND86435.1 - 2.4 7.3 6.4 5.4 6.2 6.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 KND86435.1 - 2.5 8.1 5.7 6.4 6.8 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SlyX PF04102.12 KND86435.1 - 4.1 8.1 8.1 0.89 10.2 3.2 2.5 2 1 1 3 3 2 0 SlyX CdvA PF18822.1 KND86435.1 - 4.6 7.1 11.2 3.7 7.4 3.5 2.2 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF16 PF01519.16 KND86435.1 - 5 7.7 6.9 24 5.5 1.9 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 SOAR PF16533.5 KND86435.1 - 7.6 6.6 7.7 7.4 6.6 5.2 2.0 1 1 1 2 2 2 0 STIM1 Orai1-activating region PXA PF02194.15 KND86436.1 - 1e-51 175.5 0.1 6.4e-51 172.9 0.1 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KND86436.1 - 1.2e-27 96.6 0.1 4.9e-27 94.7 0.1 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KND86436.1 - 4.9e-20 71.6 1.3 1.6e-19 70.0 0.6 2.2 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KND86436.1 - 1.3e-12 48.0 0.2 3.5e-12 46.6 0.2 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain bZIP_1 PF00170.21 KND86437.1 - 0.007 16.4 4.5 0.011 15.8 4.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND86437.1 - 0.073 13.2 3.9 0.11 12.5 3.9 1.3 1 0 0 1 1 1 0 Basic region leucine zipper GST_N PF02798.20 KND86438.1 - 2.8e-09 37.2 0.0 4.8e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KND86438.1 - 1.7e-08 34.5 0.1 1.5e-07 31.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KND86438.1 - 1.9e-07 31.3 0.0 6.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KND86438.1 - 6.6e-07 29.6 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND86438.1 - 6.5e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND86438.1 - 6.7e-05 23.0 0.0 0.00015 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain VF530 PF09905.9 KND86438.1 - 0.17 12.1 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 DNA-binding protein VF530 Methyltransf_4 PF02390.17 KND86439.1 - 2.1e-52 177.1 0.0 2.6e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KND86439.1 - 0.00096 19.8 0.0 0.0028 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86439.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KND86439.1 - 0.03 15.1 0.0 0.091 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KND86439.1 - 0.05 13.2 0.0 0.091 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KND86439.1 - 0.16 12.7 0.0 0.98 10.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KND86443.1 - 1.2e-22 79.5 0.0 1.8e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND86443.1 - 0.28 11.1 0.0 24 4.9 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif PEX11 PF05648.14 KND86444.1 - 1.8e-66 223.8 0.0 2e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.20 KND86445.1 - 8.1e-70 234.1 0.1 1e-69 233.8 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CIA30 PF08547.12 KND86446.1 - 2.1e-35 122.1 0.0 2.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Homoserine_dh PF00742.19 KND86447.1 - 8.1e-53 178.9 0.0 1e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KND86447.1 - 2.6e-19 70.0 0.0 4.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 KND86448.1 - 8.4e-29 99.7 15.6 8.4e-29 99.7 15.6 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) SGL PF08450.12 KND86449.1 - 6.8e-05 22.6 0.7 0.028 14.0 0.0 2.7 3 0 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KND86449.1 - 0.00031 20.6 0.5 0.014 15.4 0.0 3.4 3 1 1 4 4 4 1 NHL repeat GSDH PF07995.11 KND86449.1 - 0.011 15.0 3.3 0.52 9.6 1.3 3.4 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase PD40 PF07676.12 KND86449.1 - 0.02 14.8 0.0 0.064 13.2 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.6 KND86449.1 - 0.59 10.0 4.7 10 6.0 1.2 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.32 KND86450.1 - 1.8e-23 82.4 17.1 2.1e-05 25.2 0.1 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND86450.1 - 2.8e-11 43.6 5.0 0.00048 20.4 0.0 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain NAD_binding_10 PF13460.6 KND86450.1 - 2.2e-06 27.7 0.0 6.3e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding TFIIIC_delta PF12657.7 KND86450.1 - 0.0021 18.0 8.6 0.17 11.8 0.4 3.7 2 2 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 KND86450.1 - 0.022 13.7 0.4 0.85 8.5 0.0 3.2 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Semialdhyde_dh PF01118.24 KND86450.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KND86450.1 - 0.083 12.0 0.0 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein DUF3245 PF11595.8 KND86450.1 - 0.25 11.8 1.7 14 6.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) UL42 PF17638.2 KND86452.1 - 0.041 13.9 0.0 0.041 13.9 0.0 3.4 3 0 0 3 3 3 0 HCMV UL42 Pkinase PF00069.25 KND86453.1 - 4.1e-69 232.9 0.0 7.4e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86453.1 - 1.5e-39 135.9 0.0 4.9e-39 134.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KND86453.1 - 6.4e-21 73.9 0.1 1.2e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KND86453.1 - 1.7e-06 27.2 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND86453.1 - 6.5e-05 22.4 0.1 0.00013 21.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND86453.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND86453.1 - 0.0038 17.2 0.0 0.017 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND86453.1 - 0.045 13.4 0.9 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 KND86453.1 - 0.11 12.0 0.2 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 KND86454.1 - 9.6e-38 127.9 2.1 3.6e-37 126.1 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KND86454.1 - 3e-05 23.8 6.1 3.8e-05 23.5 1.1 3.0 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 KND86454.1 - 0.0031 17.6 0.4 0.013 15.6 0.4 2.2 1 0 0 1 1 1 1 G-patch domain DUF3328 PF11807.8 KND86455.1 - 4.2e-36 124.8 1.9 5.7e-36 124.3 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RAI16-like PF10257.9 KND86457.1 - 5.8e-74 249.1 0.7 8.5e-74 248.6 0.7 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF829 PF05705.14 KND86458.1 - 1.6e-52 178.8 0.0 1.8e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 2TM PF13239.6 KND86458.1 - 0.15 12.4 0.5 0.32 11.3 0.5 1.5 1 0 0 1 1 1 0 2TM domain bZIP_1 PF00170.21 KND86459.1 - 2.2e-05 24.5 5.0 3.7e-05 23.7 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND86459.1 - 6e-05 23.0 8.0 0.00011 22.2 8.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Fes1 PF08609.10 KND86459.1 - 0.039 14.8 0.0 0.13 13.2 0.0 2.0 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 TTKRSYEDQ PF10212.9 KND86459.1 - 0.046 12.7 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Ank_4 PF13637.6 KND86460.1 - 1.6e-15 57.3 0.5 4.2e-06 27.2 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND86460.1 - 8.5e-15 55.1 0.1 6.7e-14 52.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KND86460.1 - 1.1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KND86460.1 - 1.4e-08 34.8 0.1 0.026 15.0 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KND86460.1 - 1.5e-08 34.2 0.2 0.16 12.6 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KND86460.1 - 2.1e-06 27.9 0.1 0.0059 16.9 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 KND86460.1 - 4.3e-05 24.0 0.1 0.00011 22.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND86460.1 - 6.6e-05 23.2 0.1 0.00024 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KND86460.1 - 0.007 15.6 0.1 0.017 14.3 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 KND86460.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KND86460.1 - 0.057 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KND86460.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KND86460.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KND86460.1 - 0.093 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1373 PF07117.11 KND86461.1 - 5.8 6.9 19.7 8.1 6.4 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Rcd1 PF04078.13 KND86462.1 - 2.2e-125 417.2 4.5 2.7e-125 416.9 4.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Med15 PF09606.10 KND86462.1 - 0.007 15.1 20.2 0.0091 14.7 20.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 KND86462.1 - 0.011 15.8 15.8 0.014 15.4 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 KND86462.1 - 0.069 12.1 10.5 0.087 11.8 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 KND86462.1 - 0.62 9.0 7.4 0.85 8.5 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 KND86462.1 - 3.6 6.0 11.2 4.6 5.6 11.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 APH PF01636.23 KND86463.1 - 1.2e-08 35.2 0.2 1.9e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KND86464.1 - 4.2e-06 26.9 0.0 0.00013 22.0 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF3375 PF11855.8 KND86468.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) vATP-synt_AC39 PF01992.16 KND86468.1 - 0.075 12.5 0.1 0.093 12.2 0.1 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit ProQ PF04352.13 KND86468.1 - 0.085 12.8 0.2 2.7 7.9 0.1 2.4 1 1 0 2 2 2 0 ProQ/FINO family THUMP PF02926.17 KND86468.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 THUMP domain AAA_12 PF13087.6 KND86470.1 - 1.7e-41 142.1 0.0 2.8e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND86470.1 - 4.1e-12 46.4 0.1 1.5e-11 44.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KND86470.1 - 3.6e-08 33.9 0.0 1.1e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KND86470.1 - 4.9e-05 22.7 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.24 KND86470.1 - 0.00036 20.4 5.1 0.00086 19.2 5.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND86470.1 - 0.001 19.1 5.2 0.0022 18.0 5.2 1.6 1 0 0 1 1 1 1 Zinc finger domain AAA_30 PF13604.6 KND86470.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain zf-CCCH_4 PF18044.1 KND86470.1 - 0.0017 18.1 2.6 0.0044 16.8 2.6 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 KND86470.1 - 0.004 17.8 0.5 0.0093 16.7 0.5 1.5 1 0 0 1 1 1 1 Torus domain ResIII PF04851.15 KND86470.1 - 0.039 14.0 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sugar_tr PF00083.24 KND86471.1 - 0.00016 20.7 2.9 0.00017 20.6 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HisKA_7TM PF16927.5 KND86471.1 - 0.0091 16.1 1.7 0.0099 15.9 1.7 1.1 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase COX14 PF14880.6 KND86471.1 - 0.57 10.1 2.2 16 5.4 0.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c assembly Ank_2 PF12796.7 KND86472.1 - 3.9e-26 91.5 0.0 7e-18 65.0 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86472.1 - 4.8e-24 84.4 0.2 2.6e-09 37.4 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86472.1 - 6.5e-23 78.3 0.0 1.9e-05 24.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KND86472.1 - 1.5e-19 69.5 0.0 0.00021 21.6 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KND86472.1 - 4.2e-14 52.4 0.0 4.2e-08 33.3 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) SseB_C PF14581.6 KND86473.1 - 0.13 12.3 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 SseB protein C-terminal domain APH PF01636.23 KND86474.1 - 3.2e-14 53.5 0.0 5.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KND86474.1 - 6.2e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KND86474.1 - 0.00023 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KND86474.1 - 0.0005 19.0 0.0 0.00073 18.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 KND86474.1 - 0.042 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KND86475.1 - 6.8e-68 229.3 0.0 8.7e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KND86477.1 - 1.2e-22 80.6 0.5 6.1e-21 75.0 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86477.1 - 7.5e-07 28.7 0.2 2.1e-06 27.2 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND86477.1 - 2.7e-05 23.6 0.1 4.8e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND86477.1 - 0.0084 15.5 0.0 0.38 10.0 0.0 3.1 2 1 2 4 4 4 1 Kinase-like RIO1 PF01163.22 KND86477.1 - 0.016 14.8 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KND86477.1 - 0.056 12.4 0.1 0.079 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 KND86477.1 - 0.077 12.9 0.4 0.31 10.9 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family 2-Hacid_dh_C PF02826.19 KND86478.1 - 1e-28 99.9 0.0 1.2e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PALP PF00291.25 KND86478.1 - 0.00091 18.7 0.0 0.0015 18.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_2 PF03446.15 KND86478.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 KND86478.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 XdhC Rossmann domain GPHH PF16905.5 KND86479.1 - 0.12 12.2 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated MFS_1 PF07690.16 KND86480.1 - 7.5e-11 41.5 50.6 1.7e-07 30.5 15.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 KND86481.1 - 8.3e-23 81.4 0.0 1.5e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 KND86483.1 - 3.9e-67 227.0 0.0 5.2e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF-1a PF01176.19 KND86485.1 - 1.9e-21 75.6 0.0 2.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 KND86486.1 - 1.7e-24 85.9 0.2 2.3e-24 85.5 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 KND86486.1 - 6.2e-05 22.7 0.3 0.00012 21.7 0.3 1.5 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 KND86486.1 - 0.0066 16.0 1.8 0.0066 16.0 1.8 12.8 2 1 7 9 9 9 2 Adenylate cyclase associated (CAP) N terminal TMEM52 PF14979.6 KND86488.1 - 0.12 12.2 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 Transmembrane 52 SseC PF04888.12 KND86488.1 - 1.7 8.1 5.0 1.9 8.0 5.0 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CorA PF01544.18 KND86489.1 - 3.5e-14 52.8 0.8 5.2e-14 52.2 0.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein K_channel_TID PF07941.11 KND86490.1 - 0.75 10.3 3.6 24 5.5 1.3 2.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MSA-2c PF12238.8 KND86490.1 - 2.9 7.8 13.6 13 5.8 1.6 3.6 3 0 0 3 3 3 0 Merozoite surface antigen 2c zf-C2H2_4 PF13894.6 KND86492.1 - 0.001 19.7 3.1 0.001 19.7 3.1 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KND86492.1 - 0.0034 17.8 3.1 0.0034 17.8 3.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KND86492.1 - 0.0059 16.9 0.4 0.0059 16.9 0.4 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KND86492.1 - 0.75 9.9 5.2 20 5.3 0.8 3.5 3 1 0 3 3 3 0 BED zinc finger ERCC4 PF02732.15 KND86493.1 - 2.1e-19 70.3 0.0 4.2e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain 2OG-FeII_Oxy PF03171.20 KND86494.1 - 6.3e-14 52.3 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KND86494.1 - 0.1 13.4 0.8 0.34 11.7 0.0 2.0 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.23 KND86495.1 - 7.3e-100 334.1 33.0 2.6e-50 171.6 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND86495.1 - 6e-62 208.2 0.0 1.1e-32 113.4 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND86495.1 - 1.1e-12 47.8 0.2 0.00067 19.2 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND86495.1 - 7.7e-07 28.8 1.1 0.0047 16.6 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND86495.1 - 3.6e-06 27.0 0.0 0.053 13.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 KND86495.1 - 3.7e-06 26.9 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 KND86495.1 - 7.4e-06 26.4 4.0 0.079 13.3 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND86495.1 - 9.5e-06 25.9 0.2 0.24 11.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KND86495.1 - 0.00013 21.3 0.0 0.47 9.7 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KND86495.1 - 0.00033 21.1 2.0 0.19 12.1 0.0 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND86495.1 - 0.00049 19.9 2.1 0.63 9.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KND86495.1 - 0.00057 18.8 2.8 0.033 13.0 0.1 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KND86495.1 - 0.00067 19.3 1.7 0.35 10.4 0.1 3.3 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 KND86495.1 - 0.0012 18.6 0.2 0.3 10.7 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KND86495.1 - 0.0014 18.8 0.0 2.3 8.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KND86495.1 - 0.0016 18.7 0.2 0.71 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND86495.1 - 0.0023 17.9 0.0 4.7 7.2 0.0 3.2 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND86495.1 - 0.0036 16.8 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_21 PF13304.6 KND86495.1 - 0.0048 16.8 1.0 1.6 8.5 0.1 3.4 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 KND86495.1 - 0.0057 15.9 0.0 3.3 6.8 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit SbcCD_C PF13558.6 KND86495.1 - 0.0063 16.7 3.5 5.1 7.4 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 KND86495.1 - 0.0066 16.6 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain Cu_bind_CorA PF18252.1 KND86495.1 - 0.0087 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Copper(I)-binding protein CorA AAA_14 PF13173.6 KND86495.1 - 0.015 15.3 0.0 2.5 8.1 0.0 3.1 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KND86495.1 - 0.018 14.4 0.4 5.3 6.3 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Rad17 PF03215.15 KND86495.1 - 0.019 14.9 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KND86495.1 - 0.022 14.8 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 KND86495.1 - 0.029 14.8 0.1 5.3 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase APS_kinase PF01583.20 KND86495.1 - 0.03 14.2 0.1 3.4 7.5 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 KND86495.1 - 0.034 13.9 1.2 2.4 7.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KND86495.1 - 0.042 14.4 0.1 4.5 7.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KND86495.1 - 0.044 14.3 0.0 4.1 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KND86495.1 - 0.089 12.4 0.0 16 5.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dala_Dala_lig_N PF01820.21 KND86495.1 - 0.13 12.7 0.0 12 6.4 0.0 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Phage_int_SAM_1 PF02899.17 KND86495.1 - 5.3 7.4 5.5 12 6.2 0.6 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF3742 PF12553.8 KND86495.1 - 6.2 7.0 6.3 16 5.7 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) OPT PF03169.15 KND86496.1 - 1.2e-154 516.3 43.3 1.4e-154 516.1 43.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PP-binding PF00550.25 KND86497.1 - 1.5e-13 50.8 0.7 2.6e-13 50.1 0.2 1.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 KND86497.1 - 0.0073 15.0 0.0 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 Condensation domain DHDPS PF00701.22 KND86498.1 - 4.3e-63 212.7 0.0 4.8e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KND86498.1 - 0.0061 16.1 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase FMN_dh PF01070.18 KND86499.1 - 6.2e-98 328.0 0.3 1.6e-58 198.4 0.2 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KND86499.1 - 7.9e-06 25.1 0.2 1.3e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KND86499.1 - 0.0007 18.8 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KND86499.1 - 0.0061 16.0 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 KND86499.1 - 0.014 14.7 0.1 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KND86499.1 - 0.034 13.4 0.2 0.063 12.5 0.2 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 KND86499.1 - 0.1 11.9 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Helitron_like_N PF14214.6 KND86500.1 - 3.4e-08 33.9 1.0 4.2e-06 27.1 1.0 3.0 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus ABC_tran PF00005.27 KND86501.1 - 5.4e-17 62.6 0.0 8.6e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND86501.1 - 9.6e-06 25.2 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND86501.1 - 0.00012 22.0 0.1 0.0011 18.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Aa_trans PF01490.18 KND86501.1 - 0.012 14.4 1.7 0.018 13.7 1.7 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein ABC2_membrane_2 PF12679.7 KND86501.1 - 0.18 11.1 5.7 0.27 10.5 5.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Beta-lactamase PF00144.24 KND86502.1 - 1.3e-09 37.8 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KND86502.1 - 3.2e-06 27.6 0.0 5.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) RVT_1 PF00078.27 KND86503.1 - 0.0047 16.5 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FA_hydroxylase PF04116.13 KND86504.1 - 1.5e-24 86.8 24.8 3.1e-24 85.8 21.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SafA PF17073.5 KND86504.1 - 0.07 13.1 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Two-component-system connector protein Aldo_ket_red PF00248.21 KND86505.1 - 1.7e-56 191.6 0.0 2.3e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 KND86506.1 - 2.1e-67 227.9 0.0 2.5e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KND86507.1 - 0 1422.5 0.0 2.2e-74 250.5 0.0 7.1 7 0 0 7 7 7 6 AMP-binding enzyme Condensation PF00668.20 KND86507.1 - 0 1284.6 0.0 3.5e-88 296.3 0.0 9.6 9 2 0 9 9 9 8 Condensation domain PP-binding PF00550.25 KND86507.1 - 2.5e-75 248.8 7.6 1.1e-13 51.3 0.0 7.4 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KND86507.1 - 1.8e-27 96.1 8.0 0.025 15.5 0.0 8.9 8 0 0 8 8 8 6 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 KND86507.1 - 3.6e-12 46.8 0.0 2.5e-05 24.9 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KND86507.1 - 6.2e-09 36.4 0.0 0.00065 20.3 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KND86507.1 - 2.3e-08 34.1 0.0 0.011 15.5 0.0 3.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KND86507.1 - 7e-08 32.4 0.0 0.0081 16.0 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_16 PF10294.9 KND86507.1 - 0.0053 16.5 0.0 0.89 9.3 0.0 2.6 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_9 PF08003.11 KND86507.1 - 0.02 13.9 0.0 1.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TssR PF17643.1 KND86507.1 - 0.044 11.7 0.0 0.11 10.5 0.0 1.5 2 0 0 2 2 2 0 Type VI secretion system, TssR Cu-oxidase_2 PF07731.14 KND86508.1 - 1.6e-45 154.2 7.4 6.9e-41 139.2 1.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KND86508.1 - 1.1e-38 132.9 1.4 4.3e-33 114.7 0.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KND86508.1 - 2.5e-38 130.8 6.8 1.9e-37 127.9 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase AlcCBM31 PF11606.8 KND86508.1 - 0.0025 17.9 1.6 43 4.4 0.0 4.1 4 0 0 4 4 4 2 Family 31 carbohydrate binding protein FTR1 PF03239.14 KND86509.1 - 7.8e-88 294.6 9.6 9.5e-88 294.3 9.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3180 PF11377.8 KND86509.1 - 0.035 14.2 0.5 0.035 14.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) S_2TMBeta PF18153.1 KND86509.1 - 0.097 12.4 1.0 0.37 10.5 1.0 2.0 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain DUF4231 PF14015.6 KND86509.1 - 2.1 8.9 5.1 1.2 9.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Pkinase PF00069.25 KND86510.1 - 1.1e-09 38.1 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86510.1 - 5.9e-06 25.7 0.0 7e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FapA PF03961.13 KND86510.1 - 0.18 10.4 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ring_hydroxyl_A PF00848.19 KND86511.1 - 1e-25 91.0 7.1 2.9e-23 83.0 5.0 2.4 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 KND86511.1 - 1.1e-15 57.3 0.0 2.2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain p450 PF00067.22 KND86513.1 - 2.6e-24 85.8 0.0 2.7e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCV_T PF01571.21 KND86514.1 - 1.1e-69 234.7 0.0 3.4e-69 233.1 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 KND86514.1 - 1.8e-45 156.1 0.4 3.5e-45 155.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 KND86514.1 - 1.3e-22 79.5 0.0 3.6e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 KND86514.1 - 8.4e-18 64.5 0.1 7.1e-17 61.5 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 KND86514.1 - 4e-05 23.0 0.1 0.052 12.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND86514.1 - 0.00073 20.1 0.1 0.024 15.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KND86514.1 - 0.00075 18.9 0.2 0.0021 17.5 0.2 1.6 2 0 0 2 2 2 1 ThiF family TrkA_N PF02254.18 KND86514.1 - 0.0019 18.5 0.0 0.0069 16.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.24 KND86514.1 - 0.01 15.0 0.2 0.023 13.8 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KND86514.1 - 0.014 15.4 0.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND86514.1 - 0.02 15.1 0.0 0.072 13.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KND86514.1 - 0.027 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SoxG PF04268.12 KND86514.1 - 0.04 14.1 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family FAD_binding_3 PF01494.19 KND86514.1 - 0.041 13.1 0.1 0.12 11.6 0.1 1.7 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KND86514.1 - 0.077 11.8 0.0 0.83 8.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KND86514.1 - 0.17 12.1 0.1 0.42 10.9 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KND86514.1 - 0.24 10.9 0.1 0.61 9.6 0.1 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KND86515.1 - 8.4e-32 111.1 0.1 1e-31 110.9 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND86515.1 - 2.6e-06 27.5 0.4 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND86515.1 - 0.0065 16.7 0.0 0.026 14.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND86515.1 - 0.026 13.8 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND86515.1 - 0.045 12.6 0.1 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KND86515.1 - 0.047 14.0 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 KND86515.1 - 0.089 12.0 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND86515.1 - 0.12 11.4 0.2 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KND86515.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KND86515.1 - 0.14 11.4 0.0 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KND86515.1 - 0.18 10.9 0.0 0.81 8.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_4 PF01565.23 KND86516.1 - 3.8e-22 78.5 1.7 7.1e-22 77.6 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND86516.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4235 PF14019.6 KND86517.1 - 0.36 10.9 4.8 0.94 9.6 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) DUF4083 PF13314.6 KND86517.1 - 1.3 9.0 12.0 3.5 7.6 2.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) DUF3754 PF12576.8 KND86517.1 - 8.3 6.4 5.8 2.3 8.2 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) PepX_C PF08530.10 KND86520.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain NFACT-R_1 PF05670.13 KND86521.1 - 9.3e-38 129.2 0.1 1.5e-37 128.5 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Flavokinase PF01687.17 KND86523.1 - 8.2e-11 42.2 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Imm45 PF15572.6 KND86526.1 - 0.029 14.7 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 45 NmrA PF05368.13 KND86527.1 - 8.4e-35 120.4 0.0 1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND86527.1 - 4.6e-23 82.1 0.0 7.7e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND86527.1 - 1.3e-06 28.1 0.0 3.9e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KND86527.1 - 0.0029 17.8 0.0 0.0048 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 KND86527.1 - 0.04 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PAC2 PF09754.9 KND86527.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 PAC2 family RmlD_sub_bind PF04321.17 KND86527.1 - 0.14 11.3 0.0 0.41 9.7 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain FTA2 PF13095.6 KND86530.1 - 4.3e-05 23.2 0.0 4.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 PaRep2a PF07903.11 KND86530.1 - 0.039 13.8 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 PaRep2a protein APH PF01636.23 KND86531.1 - 2.7e-11 43.9 0.0 4.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KND86531.1 - 0.00041 19.3 0.0 0.00055 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 KND86533.1 - 6.5e-37 127.3 0.0 1e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86533.1 - 4.6e-16 58.9 0.0 6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND86533.1 - 0.00095 18.0 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND86533.1 - 0.0018 18.2 0.8 0.0018 18.2 0.8 2.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KND86533.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KND86533.1 - 0.099 11.9 0.0 0.42 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Cyclin PF08613.11 KND86534.1 - 5.6e-44 150.3 0.0 1e-43 149.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin PAT1 PF09770.9 KND86534.1 - 2 6.6 7.7 3 6.0 7.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HeLo PF14479.6 KND86536.1 - 8e-07 29.1 0.3 0.041 13.7 0.0 2.5 1 1 1 2 2 2 2 Prion-inhibition and propagation RINGv PF12906.7 KND86537.1 - 6.4e-17 61.4 7.0 1.1e-16 60.6 7.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KND86537.1 - 0.011 16.0 6.5 0.02 15.2 6.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KND86537.1 - 0.12 12.4 3.2 0.25 11.4 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND86537.1 - 5.2 6.9 6.6 9.7 6.1 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF842 PF05811.13 KND86538.1 - 0.031 14.0 0.3 6 6.6 0.0 3.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) ApoO PF09769.9 KND86538.1 - 1.6 8.7 7.1 6.5 6.7 0.0 5.0 5 2 1 6 6 6 0 Apolipoprotein O ACC_central PF08326.12 KND86539.1 - 1.5e-272 906.2 0.0 1.8e-272 905.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KND86539.1 - 1.2e-183 611.3 0.0 1.6e-183 610.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KND86539.1 - 1.4e-51 175.0 0.0 3.4e-51 173.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KND86539.1 - 5.1e-22 78.0 0.0 1.4e-19 70.2 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KND86539.1 - 1.2e-16 60.3 0.7 3.3e-16 58.9 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KND86539.1 - 0.00045 20.0 0.1 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 KND86539.1 - 0.024 14.7 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KND86539.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KND86539.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon p450 PF00067.22 KND86540.1 - 2.3e-52 178.3 0.0 1.1e-45 156.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 FAD_binding_3 PF01494.19 KND86541.1 - 1.5e-20 73.7 1.1 2.8e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KND86541.1 - 0.0015 17.6 0.0 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KND86541.1 - 0.0029 17.8 0.1 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND86541.1 - 0.026 14.1 1.6 0.77 9.3 1.6 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND86541.1 - 0.038 13.2 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND86541.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DASH_Duo1 PF08651.10 KND86542.1 - 0.055 13.2 0.2 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 AA_permease PF00324.21 KND86543.1 - 1.2e-117 393.5 36.9 1.3e-117 393.3 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND86543.1 - 1.4e-23 83.5 39.8 1.8e-23 83.1 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3376 PF11856.8 KND86543.1 - 0.22 10.5 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) TPR_12 PF13424.6 KND86544.1 - 1.8e-75 249.2 38.3 1.4e-19 70.2 1.6 6.9 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KND86544.1 - 1.4e-72 237.8 31.6 8.7e-11 41.3 0.1 10.0 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 KND86544.1 - 6.6e-27 91.5 22.5 0.00086 19.2 0.2 8.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 KND86544.1 - 6e-24 82.8 24.8 0.0024 17.6 1.1 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 KND86544.1 - 1e-16 61.2 10.4 0.012 16.2 1.7 7.0 6 2 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KND86544.1 - 5.5e-15 54.3 12.3 1.4 9.4 0.2 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 KND86544.1 - 5.2e-12 45.3 5.6 4 8.0 0.0 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_4 PF07721.14 KND86544.1 - 1.2e-11 44.0 0.0 3.7 8.4 0.0 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KND86544.1 - 1.2e-11 44.6 11.8 3.7e-06 26.5 5.5 3.1 1 1 2 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KND86544.1 - 2e-11 43.1 20.9 0.28 11.4 0.3 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KND86544.1 - 1.5e-08 35.0 22.6 0.02 15.4 0.2 6.8 4 2 1 6 6 6 4 Tetratricopeptide repeat NB-ARC PF00931.22 KND86544.1 - 9e-08 31.6 0.0 4.3e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 KND86544.1 - 1.8e-07 31.3 5.6 0.72 10.1 0.0 5.7 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 KND86544.1 - 5.4e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 KND86544.1 - 8.2e-07 29.3 22.0 6.7 7.8 0.0 8.5 8 1 1 9 9 7 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KND86544.1 - 1.1e-06 28.7 12.6 0.78 9.6 0.1 6.6 3 2 3 6 6 6 2 Virulence factor membrane-bound polymerase, C-terminal AAA_25 PF13481.6 KND86544.1 - 2.5e-05 23.9 0.0 8e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND86544.1 - 0.00018 21.8 0.0 0.0013 19.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Tcf25 PF04910.14 KND86544.1 - 0.0011 18.2 0.2 7.2 5.6 0.0 4.1 3 2 2 5 5 5 1 Transcriptional repressor TCF25 AAA_16 PF13191.6 KND86544.1 - 0.0034 17.8 1.2 0.012 16.0 0.5 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KND86544.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MIT PF04212.18 KND86544.1 - 0.85 9.7 13.7 18 5.5 0.0 5.6 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 KND86544.1 - 1.7 8.7 10.6 41 4.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat APH PF01636.23 KND86545.1 - 1.1e-15 58.2 0.0 2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_31 PF13847.6 KND86546.1 - 9.1e-13 48.3 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND86546.1 - 3.8e-12 46.7 0.0 7.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86546.1 - 1.2e-11 45.2 0.0 2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND86546.1 - 3.9e-08 33.9 0.0 5.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND86546.1 - 8.9e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KND86546.1 - 8.2e-05 22.1 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND86546.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FtsJ PF01728.19 KND86546.1 - 0.0013 18.9 0.1 0.0046 17.1 0.1 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KND86546.1 - 0.0026 17.1 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KND86546.1 - 0.0026 17.2 0.0 0.0061 16.0 0.0 1.5 1 1 1 2 2 2 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KND86546.1 - 0.0064 15.9 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KND86546.1 - 0.017 14.7 0.0 0.033 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 KND86546.1 - 0.043 13.5 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 KND86546.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase DUF4295 PF14128.6 KND86546.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Pox_MCEL PF03291.16 KND86546.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MetW PF07021.12 KND86546.1 - 0.16 11.5 0.1 0.45 10.1 0.1 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW FAD_binding_4 PF01565.23 KND86547.1 - 6.3e-38 129.7 7.6 1.1e-37 128.8 7.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND86547.1 - 6.7e-09 35.7 0.2 1.3e-08 34.8 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KND86547.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Peripla_BP_4 PF13407.6 KND86547.1 - 0.062 12.9 0.1 0.14 11.7 0.1 1.5 2 0 0 2 2 2 0 Periplasmic binding protein domain ABC_tran PF00005.27 KND86548.1 - 1.6e-41 142.0 0.0 1.7e-25 90.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 KND86548.1 - 1.4e-20 74.1 11.2 1.2e-15 57.9 3.1 4.0 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 KND86548.1 - 1.3e-11 44.4 0.2 0.0063 16.0 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND86548.1 - 3e-06 26.9 0.6 0.015 15.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KND86548.1 - 1.2e-05 25.7 0.1 0.14 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND86548.1 - 6.4e-05 22.9 0.0 0.25 11.3 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KND86548.1 - 0.00012 22.6 0.3 0.67 10.4 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KND86548.1 - 0.00064 20.0 0.1 0.22 11.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KND86548.1 - 0.0012 18.7 1.4 0.86 9.4 0.0 3.5 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 KND86548.1 - 0.0021 18.1 0.4 0.11 12.6 0.1 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase T2SSE PF00437.20 KND86548.1 - 0.0026 16.9 0.5 1 8.4 0.5 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 KND86548.1 - 0.0037 17.4 0.5 0.0084 16.2 0.5 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain Zeta_toxin PF06414.12 KND86548.1 - 0.0065 15.8 0.2 0.82 8.9 0.1 2.6 2 0 0 2 2 2 1 Zeta toxin SbcCD_C PF13558.6 KND86548.1 - 0.007 16.6 0.0 3.1 8.1 0.0 3.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KND86548.1 - 0.019 14.8 0.1 17 5.1 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 KND86548.1 - 0.021 14.2 0.1 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 KND86548.1 - 0.029 14.4 0.2 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 KND86548.1 - 0.042 14.4 0.0 5.1 7.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 KND86548.1 - 0.054 13.1 0.1 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KND86548.1 - 0.069 12.4 0.1 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KND86548.1 - 0.29 10.7 1.1 5.8 6.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KND86548.1 - 0.3 11.0 1.1 24 4.8 0.1 2.7 2 0 0 2 2 2 0 NACHT domain HofP PF10748.9 KND86549.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA utilization proteins HofP Ferric_reduct PF01794.19 KND86550.1 - 2e-18 66.7 12.7 2e-18 66.7 12.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND86550.1 - 7.4e-12 45.3 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KND86550.1 - 4.1e-07 30.3 0.0 5.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF1263 PF06882.12 KND86550.1 - 0.023 14.7 0.9 0.063 13.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) OPT PF03169.15 KND86552.1 - 6.6e-147 490.8 42.5 7.6e-147 490.6 42.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TNFR_16_TM PF18422.1 KND86552.1 - 0.25 11.3 1.5 0.55 10.2 0.1 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF4407 PF14362.6 KND86553.1 - 0.0066 15.8 10.4 0.0093 15.4 10.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NUDE_C PF04880.13 KND86554.1 - 2.9e-43 148.4 8.1 2.9e-43 148.4 8.1 4.2 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region ERM PF00769.19 KND86554.1 - 0.0078 16.1 18.7 0.0078 16.1 18.7 2.3 1 1 1 2 2 2 1 Ezrin/radixin/moesin family ZapB PF06005.12 KND86554.1 - 0.015 15.7 10.5 0.015 15.7 10.5 4.6 2 1 2 4 4 3 0 Cell division protein ZapB Chibby PF14645.6 KND86554.1 - 0.12 12.8 10.8 0.96 9.9 1.0 2.7 1 1 1 2 2 2 0 Chibby family Tropomyosin_1 PF12718.7 KND86554.1 - 0.14 12.3 31.1 0.82 9.8 18.3 3.4 2 1 1 3 3 3 0 Tropomyosin like Fez1 PF06818.15 KND86554.1 - 0.17 12.3 28.1 0.77 10.2 16.0 3.0 2 1 1 3 3 3 0 Fez1 Fmp27_WPPW PF10359.9 KND86554.1 - 0.21 10.4 17.5 1.3 7.7 17.4 2.0 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tho2 PF11262.8 KND86554.1 - 0.41 9.8 15.1 0.022 14.0 3.9 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PSII_Pbs27 PF13326.6 KND86554.1 - 1.8 8.9 5.5 0.29 11.4 1.2 1.9 2 0 0 2 2 2 0 Photosystem II Pbs27 Filament PF00038.21 KND86554.1 - 3.4 7.2 31.5 6.1 6.3 29.4 2.2 2 1 0 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.20 KND86554.1 - 3.5 7.6 25.3 6.4 6.8 6.1 4.7 2 1 2 4 4 4 0 Prefoldin subunit YabA PF06156.13 KND86554.1 - 3.8 8.2 19.8 0.34 11.6 7.5 3.2 2 1 0 3 3 3 0 Initiation control protein YabA Peptidase_S8 PF00082.22 KND86555.1 - 1.3e-40 139.5 0.0 5.3e-40 137.5 0.0 1.8 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KND86555.1 - 2e-11 44.6 0.0 3.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 KND86555.1 - 1.3e-08 34.8 0.7 1.3e-08 34.8 0.7 2.2 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 KND86555.1 - 0.00027 20.7 0.3 0.00099 18.9 0.1 2.1 2 0 0 2 2 2 1 FlgD Ig-like domain 4HBT PF03061.22 KND86555.1 - 0.78 10.1 0.0 0.78 10.1 0.0 2.8 3 0 0 3 3 3 0 Thioesterase superfamily DUF4232 PF14016.6 KND86555.1 - 1.9 8.6 9.7 0.58 10.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) BolA PF01722.18 KND86556.1 - 1.8e-09 37.7 0.0 5.1e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein ArAE_2_N PF10337.9 KND86557.1 - 4.5e-111 372.2 2.4 1.6e-109 367.1 0.8 2.1 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 KND86557.1 - 1.7e-63 214.5 0.1 7.7e-61 205.8 0.0 2.4 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 KND86557.1 - 1.1e-09 38.4 14.0 1.1e-09 38.4 14.0 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KND86557.1 - 0.00014 20.9 4.8 0.00027 19.9 4.8 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter PH_10 PF15411.6 KND86561.1 - 1.5e-40 138.3 0.1 2.8e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 KND86561.1 - 1.9e-32 111.4 0.0 3.4e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 KND86561.1 - 1.9e-23 83.7 0.0 3.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KND86561.1 - 6.4e-08 32.4 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 KND86563.1 - 2.7e-24 85.0 6.0 0.00053 20.7 0.0 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 KND86563.1 - 1e-12 47.7 2.0 1e-12 47.7 2.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND86563.1 - 5e-07 29.4 0.4 3.5e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 KND86563.1 - 0.00028 21.1 0.1 0.74 10.2 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND86563.1 - 0.0013 17.5 0.2 0.39 9.3 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 SmpA_OmlA PF04355.13 KND86563.1 - 0.0078 16.0 1.0 0.45 10.3 0.0 3.4 4 0 0 4 4 4 1 SmpA / OmlA family MgtE_N PF03448.17 KND86563.1 - 0.0099 16.5 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 1 MgtE intracellular N domain F-box_4 PF15966.5 KND86563.1 - 0.013 15.4 0.0 0.041 13.8 0.0 1.9 1 0 0 1 1 1 0 F-box PALB2_WD40 PF16756.5 KND86563.1 - 0.023 13.6 0.1 0.2 10.5 0.0 2.3 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Snf7 PF03357.21 KND86564.1 - 1.1e-39 135.8 9.7 1.3e-39 135.5 9.7 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KND86564.1 - 2.7e-05 24.5 3.6 0.0083 16.6 1.9 2.9 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein Zwint PF15556.6 KND86564.1 - 0.0086 15.6 7.4 0.012 15.2 7.4 1.3 1 0 0 1 1 1 1 ZW10 interactor CENP-F_leu_zip PF10473.9 KND86564.1 - 0.0099 15.9 12.7 0.16 12.0 12.7 2.3 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2205 PF10224.9 KND86564.1 - 0.034 14.1 2.5 0.034 14.1 2.5 2.4 2 1 1 3 3 3 0 Short coiled-coil protein Prominin PF05478.11 KND86564.1 - 0.12 10.3 1.9 0.14 10.1 1.9 1.2 1 0 0 1 1 1 0 Prominin DUF848 PF05852.11 KND86564.1 - 0.13 12.3 7.2 0.26 11.4 6.3 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Muted PF14942.6 KND86564.1 - 0.21 11.9 9.1 0.48 10.8 3.5 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Allexi_40kDa PF05549.11 KND86564.1 - 0.27 10.7 2.3 3.2 7.2 0.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DASH_Dam1 PF08653.10 KND86564.1 - 0.45 10.3 3.5 12 5.7 0.1 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 NYD-SP28_assoc PF14775.6 KND86564.1 - 0.7 10.0 6.6 11 6.2 1.7 3.0 2 1 1 3 3 3 0 Sperm tail C-terminal domain FadA PF09403.10 KND86564.1 - 0.73 10.4 10.7 0.63 10.6 7.8 2.3 2 0 0 2 2 2 0 Adhesion protein FadA FapA PF03961.13 KND86564.1 - 0.8 8.2 9.9 3.5 6.1 7.9 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Mod_r PF07200.13 KND86564.1 - 0.97 9.5 10.5 0.41 10.7 6.9 1.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 KND86564.1 - 1 10.0 8.4 2.4 8.8 4.4 2.6 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 KND86564.1 - 1 8.6 7.1 1.4 8.2 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 KND86564.1 - 1.1 9.8 16.6 2.3 8.8 6.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region SlyX PF04102.12 KND86564.1 - 1.4 9.6 8.3 56 4.5 0.8 3.5 1 1 1 2 2 2 0 SlyX DUF3450 PF11932.8 KND86564.1 - 2.3 7.4 13.3 6.1 6.1 12.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 KND86564.1 - 2.3 8.7 12.3 19 5.8 4.3 4.0 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 KND86564.1 - 3.1 7.8 8.9 2.2 8.2 1.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DUF4337 PF14235.6 KND86564.1 - 5.4 7.1 10.2 4 7.5 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) XhlA PF10779.9 KND86564.1 - 5.6 7.2 11.5 6.5 7.0 0.1 3.6 2 1 1 3 3 3 0 Haemolysin XhlA IFRD PF05004.13 KND86566.1 - 0.0031 16.7 0.0 0.049 12.7 0.0 2.3 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 KND86566.1 - 0.0039 16.8 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 CLASP N terminal TAN PF11640.8 KND86566.1 - 0.0063 16.7 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.7 KND86566.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KND86566.1 - 0.056 13.7 1.4 9.2 6.8 0.1 4.2 5 0 0 5 5 3 0 HEAT repeat CCDC144C PF14915.6 KND86566.1 - 0.16 11.0 10.6 0.27 10.3 10.6 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region CENP-F_N PF10481.9 KND86566.1 - 0.21 11.2 4.5 0.037 13.7 0.5 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain Golgin_A5 PF09787.9 KND86566.1 - 0.25 10.7 5.5 0.51 9.8 5.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KND86566.1 - 0.36 11.1 12.1 0.84 9.9 12.1 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CASP_C PF08172.12 KND86566.1 - 0.42 9.9 5.8 7.5 5.8 0.2 2.3 1 1 1 2 2 2 0 CASP C terminal Atg14 PF10186.9 KND86566.1 - 0.6 9.1 3.7 1.3 8.1 3.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 KND86566.1 - 1.4 9.4 7.2 4.2 7.8 7.2 1.8 1 0 0 1 1 1 0 Fez1 HALZ PF02183.18 KND86566.1 - 1.7 8.9 11.3 1.8 8.8 2.2 2.9 3 0 0 3 3 2 0 Homeobox associated leucine zipper SHE3 PF17078.5 KND86566.1 - 2.1 8.0 9.7 4.2 7.0 9.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 KND86566.1 - 2.2 8.4 8.2 0.44 10.6 3.2 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 KND86566.1 - 2.3 8.3 3.6 5.7 7.0 1.5 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 KND86566.1 - 2.8 7.2 13.4 2.7 7.3 10.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GIT_CC PF16559.5 KND86566.1 - 4.9 7.1 5.4 13 5.7 1.3 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 KND86566.1 - 6.3 7.5 5.1 32 5.2 5.1 2.2 1 1 0 1 1 1 0 Initiation control protein YabA BLOC1_2 PF10046.9 KND86566.1 - 6.8 7.1 7.4 3.2 8.1 1.7 3.0 3 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.8 KND86566.1 - 7 6.7 11.8 15 5.6 11.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 KND86566.1 - 8.3 5.7 9.9 1.4 8.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KND86566.1 - 8.6 5.1 9.7 9.7 5.0 7.3 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.25 KND86567.1 - 9.1e-30 103.9 0.0 3.8e-29 101.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86567.1 - 3e-07 30.0 0.0 0.029 13.7 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase GCFC PF07842.12 KND86568.1 - 1.6e-66 224.8 1.6 1.6e-66 224.8 1.6 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KND86568.1 - 6.5e-13 48.4 2.7 6.5e-13 48.4 2.7 2.3 2 0 0 2 2 2 1 G-patch domain TIP_N PF12457.8 KND86568.1 - 5.6e-09 36.3 22.1 5.6e-09 36.3 22.1 3.3 2 2 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KND86568.1 - 1.2e-07 31.7 6.4 2.7e-07 30.5 1.6 3.3 3 1 0 3 3 3 1 G-patch domain Cwf_Cwc_15 PF04889.12 KND86568.1 - 0.17 11.6 25.4 0.062 13.0 16.6 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KND86568.1 - 0.84 7.8 25.4 0.32 9.2 4.9 2.1 2 0 0 2 2 2 0 Nop14-like family SAPS PF04499.15 KND86569.1 - 1.1e-187 624.8 0.0 2.8e-187 623.4 0.0 1.8 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein PRIMA1 PF16101.5 KND86569.1 - 0.66 10.0 7.4 2.3 8.3 7.4 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Condensation PF00668.20 KND86570.1 - 1.4e-63 215.2 0.0 4.9e-26 91.4 0.0 4.8 4 2 0 4 4 4 3 Condensation domain AMP-binding PF00501.28 KND86570.1 - 4.3e-21 75.0 0.0 7.8e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 KND86570.1 - 5.9e-07 29.7 0.1 1.9e-06 28.1 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site OPT PF03169.15 KND86571.1 - 1.7e-165 552.2 47.4 2e-165 551.9 47.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1286 PF06939.11 KND86571.1 - 2.4 8.5 5.5 61 3.9 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1286) zf-C2H2 PF00096.26 KND86572.1 - 0.042 14.3 0.8 0.042 14.3 0.8 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND86572.1 - 0.074 13.5 0.4 0.074 13.5 0.4 3.9 5 0 0 5 5 5 0 Zinc-finger double domain zf-CHCC PF10276.9 KND86572.1 - 0.13 12.3 2.8 6.7 6.9 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger domain DSPc PF00782.20 KND86573.1 - 4.2e-14 52.5 0.0 6.2e-07 29.3 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KND86573.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Rit1 DUSP-like domain Vfa1 PF08432.10 KND86574.1 - 5.8e-42 144.1 25.2 5.8e-42 144.1 25.2 1.3 2 0 0 2 2 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 KND86574.1 - 0.0022 16.4 15.8 0.0021 16.4 15.8 1.0 1 0 0 1 1 1 1 CDC45-like protein TAF4 PF05236.14 KND86574.1 - 0.008 16.0 11.9 0.01 15.6 11.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF5427 PF10310.9 KND86574.1 - 0.035 13.1 12.6 0.042 12.8 12.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF908 PF06012.12 KND86574.1 - 0.037 13.4 3.9 0.039 13.4 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Nop14 PF04147.12 KND86574.1 - 0.058 11.6 22.5 0.067 11.4 22.5 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 KND86574.1 - 0.071 12.1 9.5 0.087 11.8 9.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 KND86574.1 - 0.076 12.0 5.0 0.073 12.0 5.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 KND86574.1 - 0.1 12.8 2.2 0.12 12.6 2.2 1.3 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 KND86574.1 - 0.17 10.9 1.1 0.22 10.5 1.1 1.3 1 0 0 1 1 1 0 CLN3 protein MCM_bind PF09739.9 KND86574.1 - 0.28 9.6 11.2 0.32 9.4 11.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Borrelia_P83 PF05262.11 KND86574.1 - 0.55 8.7 19.4 0.63 8.5 19.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.7 KND86574.1 - 0.92 7.6 7.3 0.99 7.4 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TT_ORF2 PF02957.15 KND86574.1 - 2 9.3 14.4 3.5 8.6 14.4 1.4 1 0 0 1 1 1 0 TT viral ORF2 Serinc PF03348.15 KND86574.1 - 2.6 6.9 4.5 3 6.7 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4228 PF14009.6 KND86574.1 - 3.2 8.1 7.2 4.8 7.5 7.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Presenilin PF01080.17 KND86574.1 - 4.5 5.9 15.6 5.8 5.6 15.6 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 KND86574.1 - 4.7 7.2 4.8 4.8 7.2 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 KND86574.1 - 4.7 5.5 4.2 5.1 5.4 4.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 KND86574.1 - 4.8 6.9 20.8 6.6 6.5 20.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 KND86574.1 - 4.9 6.5 17.8 6.5 6.1 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 KND86574.1 - 6 6.1 22.5 8.6 5.6 22.5 1.3 1 0 0 1 1 1 0 NOA36 protein AAA_11 PF13086.6 KND86574.1 - 7.1 6.3 12.2 9.5 5.9 12.2 1.1 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 KND86574.1 - 7.5 5.0 13.1 8.9 4.8 13.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator SpoIIP PF07454.11 KND86574.1 - 7.7 5.9 17.3 11 5.3 17.3 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rtt106 PF08512.12 KND86575.1 - 9.3e-28 96.5 0.0 2.1e-27 95.3 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KND86575.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain SDA1 PF05285.12 KND86575.1 - 0.5 9.7 25.8 0.73 9.2 25.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KND86575.1 - 1.1 7.4 31.8 1.5 6.9 31.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KND86575.1 - 2.2 6.5 16.1 3.2 5.9 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KND86575.1 - 2.7 7.2 27.1 4.1 6.7 27.1 1.1 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 KND86575.1 - 3.4 7.7 24.7 7.9 6.5 24.7 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nucleos_tra2_C PF07662.13 KND86578.1 - 5.4e-70 235.5 0.7 5.4e-70 235.5 0.7 2.8 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KND86578.1 - 1.4e-22 80.1 1.8 1.4e-22 80.1 1.8 2.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KND86578.1 - 1.3 9.3 19.4 0.022 15.0 8.3 3.3 4 0 0 4 4 4 0 Nucleoside recognition HRI1 PF16815.5 KND86579.1 - 1.4e-71 240.9 0.1 1.5e-71 240.7 0.1 1.0 1 0 0 1 1 1 1 Protein HRI1 Acetyltransf_2 PF00797.17 KND86580.1 - 8.3e-44 150.2 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 KND86580.1 - 0.014 15.8 0.0 0.041 14.3 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily ATP_synth_reg PF14960.6 KND86580.1 - 0.11 12.1 0.0 0.32 10.5 0.0 1.8 1 1 1 2 2 2 0 ATP synthase regulation Aminotran_3 PF00202.21 KND86581.1 - 9.4e-84 281.4 0.0 1.2e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Kinesin PF00225.23 KND86582.1 - 2.6e-57 194.2 0.0 4.4e-57 193.5 0.0 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND86582.1 - 7.5e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Glyco_hydro_47 PF01532.20 KND86583.1 - 1.6e-164 548.2 0.0 1.8e-164 548.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Amidohydro_3 PF07969.11 KND86584.1 - 1.4e-77 262.1 0.3 1.6e-77 262.0 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KND86584.1 - 1.2e-09 37.9 0.0 2.7e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Sacchrp_dh_C PF16653.5 KND86585.1 - 1.4e-78 264.7 0.0 7.4e-75 252.5 0.0 2.3 1 1 0 2 2 2 2 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KND86585.1 - 8.5e-24 84.3 1.6 1.4e-23 83.5 1.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KND86585.1 - 2.2e-07 30.9 1.1 4.3e-07 30.0 1.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KND86585.1 - 5.2e-07 29.8 0.1 1.6e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 KND86585.1 - 0.0035 16.9 1.3 0.0053 16.4 1.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_3 PF03447.16 KND86585.1 - 0.056 14.1 0.9 0.095 13.4 0.9 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KND86585.1 - 0.11 12.9 0.2 0.22 12.0 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3429 PF11911.8 KND86586.1 - 6.6e-45 152.9 9.6 8.6e-45 152.6 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Neur_chan_memb PF02932.16 KND86586.1 - 3.7 7.5 5.0 6.1 6.8 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SHR-BD PF06650.12 KND86587.1 - 4e-95 318.3 0.1 2.2e-93 312.6 0.0 3.2 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 KND86587.1 - 1.5e-86 290.0 0.3 2.1e-84 283.0 0.0 3.5 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 KND86587.1 - 8.6e-79 264.3 14.9 1.1e-73 247.6 0.1 7.4 7 1 0 7 7 7 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 KND86587.1 - 6.5e-74 247.5 7.0 6.6e-68 228.0 0.9 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KND86587.1 - 7.6e-40 135.7 0.0 2.7e-39 133.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KND86587.1 - 5.6e-07 29.8 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain p450 PF00067.22 KND86588.1 - 3.3e-70 237.1 0.0 3.8e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 KND86589.1 - 1.1e-55 188.7 0.0 1.4e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KND86589.1 - 4.1e-31 107.3 0.0 7.3e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.6 KND86590.1 - 1.5e-10 41.3 0.0 2.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KND86590.1 - 7.4e-10 39.0 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND86590.1 - 1.3e-08 35.0 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KND86590.1 - 1.3e-05 25.3 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND86590.1 - 4.6e-05 23.5 0.0 7.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND86590.1 - 0.0019 18.2 0.2 0.0077 16.2 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain MDM31_MDM32 PF08118.11 KND86590.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Fungal_trans PF04082.18 KND86591.1 - 4.6e-21 75.1 0.1 9.4e-21 74.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86591.1 - 1.4e-07 31.5 7.5 1.4e-07 31.5 7.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KND86592.1 - 8.7e-22 77.8 0.0 4e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND86592.1 - 2.6e-07 30.8 0.3 6.7e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND86592.1 - 4.9e-07 29.2 0.4 7.7e-07 28.5 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND86592.1 - 1.1e-06 28.1 0.4 3.4e-06 26.5 0.3 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND86592.1 - 2.3e-05 24.2 0.3 0.00027 20.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 KND86592.1 - 0.00022 20.4 0.3 0.00035 19.8 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KND86592.1 - 0.00024 19.9 0.4 0.00037 19.3 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KND86592.1 - 0.00026 21.5 0.6 0.00076 20.0 0.4 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KND86592.1 - 0.0011 18.5 0.5 0.0016 17.9 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KND86592.1 - 0.0032 16.8 0.2 0.0066 15.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KND86592.1 - 0.0052 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KND86592.1 - 0.0058 16.0 0.1 0.0095 15.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KND86592.1 - 0.0081 15.1 0.0 0.24 10.2 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.18 KND86592.1 - 0.019 14.9 0.4 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KND86592.1 - 0.02 14.1 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KND86592.1 - 0.043 12.9 0.6 0.76 8.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 KND86592.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 KND86592.1 - 0.1 11.6 0.0 0.36 9.8 0.0 1.7 1 1 1 2 2 2 0 Squalene epoxidase NAD_Gly3P_dh_N PF01210.23 KND86592.1 - 0.12 12.4 0.2 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_A4 PF01828.17 KND86593.1 - 1.7e-74 249.8 10.9 2e-74 249.6 10.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family H_lectin PF09458.10 KND86593.1 - 0.049 13.8 0.3 0.13 12.5 0.1 2.0 2 1 0 2 2 2 0 H-type lectin domain Glyoxalase PF00903.25 KND86594.1 - 9.2e-07 29.1 0.3 2.3e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1995 PF09353.10 KND86594.1 - 0.054 13.5 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) DUF4396 PF14342.6 KND86595.1 - 2.4e-45 154.4 7.8 2.4e-45 154.4 7.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) BCS1_N PF08740.11 KND86596.1 - 3e-12 46.9 0.1 3.6e-12 46.6 0.1 1.1 1 0 0 1 1 1 1 BCS1 N terminal Actin PF00022.19 KND86597.1 - 2.6e-111 372.1 0.0 1.6e-110 369.5 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND86597.1 - 0.0083 15.0 0.0 0.061 12.1 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Ank_2 PF12796.7 KND86598.1 - 4.4e-133 434.2 3.9 4.4e-17 62.4 0.5 8.6 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND86598.1 - 6.2e-79 250.4 4.1 4.6e-06 26.6 0.0 15.3 14 1 1 15 15 15 14 Ankyrin repeat Ank_4 PF13637.6 KND86598.1 - 2.1e-69 229.1 16.5 3.3e-11 43.5 0.0 11.6 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KND86598.1 - 1.7e-60 199.0 25.9 5.5e-06 26.6 0.0 13.9 14 0 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 KND86598.1 - 1.6e-51 171.7 30.7 5.4e-10 39.3 0.1 12.4 2 1 12 14 14 14 13 Ankyrin repeats (many copies) FemAB_like PF04339.12 KND86598.1 - 0.06 12.5 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Peptidogalycan biosysnthesis/recognition VWA_3_C PF18571.1 KND86598.1 - 4.5 7.2 8.6 1.2e+02 2.7 0.0 5.7 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain Hydrolase_like PF13242.6 KND86598.1 - 8.9 6.5 10.8 6.6 6.9 0.2 4.1 3 1 2 5 5 5 0 HAD-hyrolase-like Pkinase PF00069.25 KND86599.1 - 1.5e-15 57.3 0.0 9.4e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain FHA PF00498.26 KND86599.1 - 3.5e-07 30.5 0.0 7.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.17 KND86599.1 - 6.6e-07 28.9 0.0 2.2e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 KND86599.1 - 0.00077 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Haspin_kinase PF12330.8 KND86599.1 - 0.0094 14.9 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KND86599.1 - 0.1 11.4 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Unstab_antitox PF09720.10 KND86600.1 - 2.5 8.2 6.9 1.2 9.2 3.2 2.4 2 1 0 2 2 2 0 Putative addiction module component Pkinase PF00069.25 KND86602.1 - 2.9e-06 26.8 0.2 6.2e-06 25.8 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain NDUF_B4 PF07225.12 KND86605.1 - 0.14 12.1 4.3 0.29 11.0 0.6 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GAPES4 PF17157.4 KND86606.1 - 0.16 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain DUF2306 PF10067.9 KND86607.1 - 1.8e-13 50.9 9.6 4.1e-13 49.8 9.6 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) HutP PF09021.11 KND86608.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 HutP HKR_ArcB_TM PF18415.1 KND86608.1 - 1.3 9.9 8.0 0.49 11.2 1.4 3.0 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain TRI12 PF06609.13 KND86609.1 - 2.2e-23 82.6 22.3 3.3e-23 81.9 22.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KND86609.1 - 1.8e-21 76.5 49.8 1.8e-20 73.2 45.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86609.1 - 1.2e-07 30.9 26.4 1.3e-05 24.3 6.0 2.8 1 1 0 2 2 2 2 Sugar (and other) transporter PorA PF11271.8 KND86609.1 - 0.14 11.4 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Porin PorA HisKA_3 PF07730.13 KND86610.1 - 0.0038 17.7 3.2 1.2 9.7 0.2 2.7 2 1 1 3 3 3 2 Histidine kinase V-ATPase_G_2 PF16999.5 KND86610.1 - 0.0047 17.3 1.9 0.0047 17.3 1.9 2.8 2 1 1 3 3 3 1 Vacuolar (H+)-ATPase G subunit DUF4686 PF15742.5 KND86610.1 - 0.0077 15.4 5.2 0.011 14.8 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Golgin_A5 PF09787.9 KND86610.1 - 0.012 15.1 3.6 0.014 14.9 3.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF948 PF06103.11 KND86610.1 - 0.013 15.8 0.4 16 5.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 KND86610.1 - 0.015 15.6 6.3 0.031 14.6 6.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 KND86610.1 - 0.021 12.4 7.6 0.029 11.9 7.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ANAPC4 PF12896.7 KND86610.1 - 0.028 13.9 2.8 0.23 10.9 2.8 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 FlaC_arch PF05377.11 KND86610.1 - 0.046 14.1 1.6 14 6.2 0.6 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FapA PF03961.13 KND86610.1 - 0.059 12.0 1.3 0.067 11.8 1.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KND86610.1 - 0.061 13.4 9.0 0.11 12.5 8.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSNAXIP1_N PF15739.5 KND86610.1 - 0.065 13.6 2.4 1.7 9.1 3.2 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Mod_r PF07200.13 KND86610.1 - 0.084 13.0 8.6 0.24 11.5 8.6 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Mt_ATP-synt_B PF05405.14 KND86610.1 - 0.1 12.2 2.8 0.16 11.6 2.8 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) XH PF03469.14 KND86610.1 - 0.12 12.3 5.3 3.8 7.4 5.3 2.7 2 1 0 2 2 2 0 XH domain FlxA PF14282.6 KND86610.1 - 0.14 12.2 2.8 0.42 10.6 2.8 1.9 1 1 0 1 1 1 0 FlxA-like protein Exonuc_VII_L PF02601.15 KND86610.1 - 0.22 11.1 6.2 0.34 10.4 6.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 KND86610.1 - 0.44 10.8 6.2 0.23 11.7 3.6 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 KND86610.1 - 0.53 10.9 9.8 0.77 10.4 1.4 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-H PF05837.12 KND86610.1 - 0.68 10.4 8.8 0.41 11.1 6.0 2.0 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KND86610.1 - 0.86 8.9 7.2 1.4 8.2 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KND86610.1 - 1.1 9.9 8.2 2.7 8.7 0.7 2.7 2 1 1 3 3 2 0 Initiation control protein YabA V-ATPase_G PF03179.15 KND86610.1 - 1.3 9.6 6.4 2.1 8.9 5.4 1.9 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Sec34 PF04136.15 KND86610.1 - 1.3 8.9 5.0 9.8 6.0 2.5 2.7 1 1 1 2 2 2 0 Sec34-like family APG6_N PF17675.1 KND86610.1 - 1.9 9.0 14.8 3.6 8.1 14.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KND86610.1 - 2.2 9.2 8.0 2 9.3 6.4 1.8 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 KND86610.1 - 2.6 8.2 10.6 0.71 10.0 2.8 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF4140 PF13600.6 KND86610.1 - 7.4 7.1 6.2 2.7 8.5 1.7 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 KND86610.1 - 9.2 6.6 9.5 1.4 9.2 1.7 2.4 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 Flavoprotein PF02441.19 KND86611.1 - 3.8e-43 147.0 0.1 4.6e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 KND86612.1 - 9.4e-15 54.6 0.0 1.3e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Aminotran_4 PF01063.19 KND86613.1 - 2.2e-26 93.1 0.0 3.1e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Methyltransf_11 PF08241.12 KND86614.1 - 6.6e-14 52.3 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86614.1 - 6.8e-14 52.4 0.1 1.2e-13 51.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND86614.1 - 1.5e-08 34.6 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86614.1 - 7.1e-06 25.9 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND86614.1 - 8.9e-06 26.4 0.0 1.4e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KND86614.1 - 5.1e-05 22.8 0.1 7e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KND86614.1 - 0.00046 19.8 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KND86614.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KND86614.1 - 0.051 12.9 0.0 0.087 12.1 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 KND86614.1 - 0.051 13.5 0.4 0.15 12.0 0.2 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 KND86614.1 - 0.099 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase N2227 PF07942.12 KND86614.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Sugar_tr PF00083.24 KND86615.1 - 3.2e-82 276.8 21.6 8.3e-82 275.4 21.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86615.1 - 1.9e-28 99.5 28.4 1.9e-28 99.5 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily COPI_assoc PF08507.10 KND86615.1 - 7 6.7 12.3 3 7.9 8.5 2.3 2 0 0 2 2 2 0 COPI associated protein Pro_isomerase PF00160.21 KND86617.1 - 5.8e-34 117.6 0.0 8.9e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KND86617.1 - 3.3e-14 52.4 0.0 5.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 KND86618.1 - 1.4e-07 31.5 8.1 2.5e-07 30.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CSTF1_dimer PF16699.5 KND86618.1 - 0.23 11.2 0.8 0.57 10.0 0.8 1.6 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain KAR9 PF08580.10 KND86618.1 - 5.2 5.5 13.9 5.8 5.3 13.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SSF PF00474.17 KND86619.1 - 4.6e-23 81.8 24.7 4.7e-23 81.7 23.2 1.8 1 1 1 2 2 2 1 Sodium:solute symporter family MFS_1 PF07690.16 KND86620.1 - 1.7e-18 66.7 61.3 6.7e-18 64.7 53.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.11 KND86620.1 - 9.4 5.9 6.7 2.7 7.6 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) CTP_transf_like PF01467.26 KND86621.1 - 1.1e-23 84.0 0.0 2.2e-21 76.6 0.0 2.9 3 0 0 3 3 3 2 Cytidylyltransferase-like Pkinase_Tyr PF07714.17 KND86622.1 - 6.9e-16 58.3 0.0 1.5e-15 57.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND86622.1 - 1.3e-14 54.2 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND86622.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND86622.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ribosomal_S24e PF01282.19 KND86623.1 - 2.2e-33 114.1 0.1 3.7e-33 113.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S24e GST_N_3 PF13417.6 KND86624.1 - 1e-13 51.5 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND86624.1 - 4.1e-10 39.8 0.0 6.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KND86624.1 - 9.1e-08 32.3 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND86624.1 - 4.3e-06 26.6 0.3 4.3e-06 26.6 0.3 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KND86624.1 - 0.16 12.3 0.0 0.58 10.5 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Arf PF00025.21 KND86625.1 - 7.3e-75 250.2 0.2 8.2e-75 250.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND86625.1 - 2.9e-14 53.3 0.0 4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KND86625.1 - 2.3e-13 50.1 1.9 1.7e-09 37.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND86625.1 - 3e-13 49.7 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KND86625.1 - 4.9e-12 45.6 0.0 6.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KND86625.1 - 7.8e-12 45.0 0.0 9.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND86625.1 - 0.00033 20.7 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KND86625.1 - 0.03 13.6 0.3 0.07 12.4 0.3 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 KND86625.1 - 0.049 13.6 1.1 0.079 12.9 1.1 1.3 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Methyltrn_RNA_3 PF02598.17 KND86625.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase Pkinase PF00069.25 KND86626.1 - 8.1e-58 195.9 0.0 1.9e-56 191.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86626.1 - 2.9e-28 98.9 0.0 9.8e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND86626.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 KND86626.1 - 0.14 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Chorion_2 PF03964.15 KND86626.1 - 0.21 12.5 19.9 0.53 11.1 6.4 2.6 2 1 0 2 2 2 0 Chorion family 2 SelP_N PF04592.14 KND86626.1 - 2.4 7.5 12.4 5.1 6.4 12.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PMI_typeI PF01238.21 KND86627.1 - 5.7e-132 440.4 0.0 6.8e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 KND86627.1 - 0.11 12.4 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1325 PF07039.11 KND86628.1 - 1e-33 116.2 0.2 1.6e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Pro_CA PF00484.19 KND86629.1 - 3e-12 47.1 0.4 9.9e-11 42.2 0.2 2.1 1 1 1 2 2 2 2 Carbonic anhydrase Acetyltransf_1 PF00583.25 KND86630.1 - 0.0052 17.0 0.0 0.19 12.0 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Amidase PF01425.21 KND86631.1 - 3.6e-93 313.0 0.0 4.6e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 Amidase PCRF PF03462.18 KND86632.1 - 1e-43 149.5 0.1 2e-43 148.6 0.0 1.5 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KND86632.1 - 3e-33 114.2 2.7 5.5e-33 113.4 2.7 1.4 1 0 0 1 1 1 1 RF-1 domain V_ATPase_I_N PF18670.1 KND86632.1 - 0.5 10.8 6.2 0.073 13.5 1.4 2.1 2 1 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain Amidase PF01425.21 KND86633.1 - 8.4e-105 351.3 0.0 1e-104 351.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Sterol-sensing PF12349.8 KND86633.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation Fungal_trans PF04082.18 KND86634.1 - 1.3e-14 53.9 0.5 2.5e-14 52.9 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND86634.1 - 6.7e-09 35.7 12.0 3e-05 24.2 5.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND86634.1 - 5.3e-06 26.8 9.4 0.00065 20.3 3.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND86634.1 - 0.0023 18.3 2.7 0.0023 18.3 2.7 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 KND86634.1 - 0.0042 17.0 1.1 0.011 15.6 1.1 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 KND86634.1 - 0.04 14.2 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-UBR PF02207.20 KND86634.1 - 0.2 11.9 4.0 0.39 10.9 4.0 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn-C2H2_12 PF18112.1 KND86634.1 - 0.2 12.1 2.3 0.51 10.8 2.3 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KND86634.1 - 0.33 11.3 3.1 0.88 9.9 3.1 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Asp_Glu_race PF01177.22 KND86635.1 - 1.9e-05 24.7 0.0 4.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Methyltransf_16 PF10294.9 KND86636.1 - 3.4e-18 66.0 0.0 5.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KND86636.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KND86636.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 KND86636.1 - 0.02 15.6 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KND86636.1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KND86636.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PNISR PF15996.5 KND86637.1 - 0.0046 17.3 1.7 0.0073 16.6 1.7 1.3 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR SPX PF03105.19 KND86637.1 - 0.09 12.7 5.7 0.11 12.4 5.7 1.1 1 0 0 1 1 1 0 SPX domain FliT PF05400.13 KND86637.1 - 0.11 13.4 7.0 0.19 12.5 2.5 2.4 2 0 0 2 2 2 0 Flagellar protein FliT RAP1 PF07218.11 KND86637.1 - 0.24 9.6 0.6 0.26 9.5 0.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.9 KND86637.1 - 0.45 10.1 12.8 0.097 12.3 8.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PRKG1_interact PF15898.5 KND86637.1 - 1.2 10.1 8.7 0.46 11.4 3.8 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4657 PF15552.6 KND86638.1 - 0.071 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) DAO PF01266.24 KND86640.1 - 5.3e-29 101.9 3.1 6.6e-29 101.6 3.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND86640.1 - 0.0009 19.8 2.7 0.0018 18.8 2.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND86640.1 - 0.0045 16.3 0.4 0.011 14.9 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND86640.1 - 0.17 12.1 1.3 0.51 10.6 1.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KND86640.1 - 0.2 11.0 1.0 0.36 10.2 1.0 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 KND86640.1 - 0.28 10.7 1.1 0.45 10.1 1.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 KND86640.1 - 0.45 9.7 1.8 0.7 9.1 0.2 1.9 2 0 0 2 2 2 0 Thi4 family G_glu_transpept PF01019.21 KND86641.1 - 9.4e-130 433.8 0.0 1.5e-129 433.1 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase NMT1_2 PF13379.6 KND86641.1 - 0.048 13.4 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Sugar_tr PF00083.24 KND86642.1 - 1.2e-74 251.9 20.4 1.6e-74 251.4 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86642.1 - 5.1e-17 61.8 36.4 1.4e-13 50.5 22.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND86642.1 - 0.00049 19.1 3.0 0.00049 19.1 3.0 2.6 2 1 1 3 3 3 1 MFS_1 like family Phage_holin_7_1 PF16081.5 KND86642.1 - 0.042 14.0 0.7 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF4381 PF14316.6 KND86642.1 - 0.14 12.4 2.4 0.4 10.9 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3792 PF12670.7 KND86642.1 - 1.9 8.7 22.9 4.2 7.6 5.5 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3792) His_Phos_1 PF00300.22 KND86644.1 - 6.5e-11 42.3 0.1 2.9e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_M20 PF01546.28 KND86646.1 - 1.3e-27 96.9 0.0 1.8e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND86646.1 - 0.00017 21.5 0.1 0.00032 20.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KND86646.1 - 0.00043 20.0 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 GCS PF03074.16 KND86648.1 - 1.1e-174 581.0 0.0 1.4e-174 580.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase UPF0160 PF03690.13 KND86650.1 - 1.7e-126 422.2 0.0 1.9e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF3669 PF12417.8 KND86651.1 - 5e-20 71.5 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Tubulin PF00091.25 KND86652.1 - 5.6e-58 196.4 0.0 8.7e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KND86652.1 - 7.7e-45 152.1 0.4 1.4e-44 151.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain MFS_1 PF07690.16 KND86652.1 - 2e-33 115.8 50.8 6.6e-29 100.9 31.7 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KND86653.1 - 7.1e-15 54.8 2.4 1.5e-14 53.6 2.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86653.1 - 9e-05 22.5 8.4 0.00014 21.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KND86654.1 - 3.6e-37 128.1 34.4 4.9e-37 127.7 34.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Spermine_synth PF01564.17 KND86655.1 - 1.1e-69 233.6 0.1 2.2e-69 232.6 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KND86655.1 - 5.6e-26 90.2 0.2 9.4e-26 89.5 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain DUF43 PF01861.16 KND86655.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_25 PF13649.6 KND86655.1 - 0.019 15.6 0.0 0.042 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.22 KND86656.1 - 9.9e-54 182.4 0.0 1.2e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Claudin_2 PF13903.6 KND86657.1 - 9.7e-05 22.2 10.0 0.0022 17.8 10.0 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 KND86657.1 - 0.00013 21.9 5.9 0.00025 21.0 5.9 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family stn_TNFRSF12A PF12191.8 KND86657.1 - 0.035 14.3 1.1 4.6 7.5 0.0 2.3 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain FtsX PF02687.21 KND86657.1 - 0.11 13.0 8.4 0.086 13.3 4.7 2.1 2 0 0 2 2 2 0 FtsX-like permease family Claudin_3 PF06653.11 KND86657.1 - 0.24 11.3 8.8 4.4 7.2 8.8 2.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like MARVEL PF01284.23 KND86657.1 - 3.4 7.7 14.7 26 4.8 14.6 2.2 1 1 0 1 1 1 0 Membrane-associating domain DUF308 PF03729.13 KND86657.1 - 3.9 7.9 15.6 0.44 10.9 2.9 3.1 2 1 2 4 4 4 0 Short repeat of unknown function (DUF308) Trp_oprn_chp PF09534.10 KND86657.1 - 8.9 6.1 11.5 1.4 8.6 0.1 2.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PhyH PF05721.13 KND86658.1 - 9e-60 202.5 0.0 1.1e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KND86658.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2373 PF10180.9 KND86659.1 - 9.1e-24 83.1 0.1 1.8e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) AF-4 PF05110.13 KND86659.1 - 0.0025 16.0 14.5 0.0025 16.0 14.5 3.0 2 1 1 3 3 3 1 AF-4 proto-oncoprotein Proteasome PF00227.26 KND86660.1 - 5.6e-49 166.2 0.1 7.7e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KND86660.1 - 5.4e-11 42.0 0.2 5.4e-11 42.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 KND86660.1 - 0.061 13.8 0.0 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 SCP-2 sterol transfer family IF-2B PF01008.17 KND86660.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family WD40 PF00400.32 KND86661.1 - 1.4e-39 133.3 16.3 5.5e-10 39.7 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND86661.1 - 4.1e-15 55.9 0.2 0.027 14.8 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND86661.1 - 6.3e-08 31.9 0.5 0.2 10.6 0.0 4.5 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KND86661.1 - 1.1e-07 30.9 1.1 0.074 11.7 0.1 4.8 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Frtz PF11768.8 KND86661.1 - 0.001 17.5 0.0 0.0022 16.4 0.0 1.5 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 KND86661.1 - 0.0013 17.9 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region PALB2_WD40 PF16756.5 KND86661.1 - 0.0022 17.0 4.9 0.003 16.5 0.1 3.2 3 2 2 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KND86661.1 - 0.0055 15.3 0.0 0.02 13.4 0.0 1.8 1 1 1 2 2 2 1 Cytochrome D1 heme domain HPS3_N PF14761.6 KND86661.1 - 0.008 15.7 0.0 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Nbas_N PF15492.6 KND86661.1 - 0.033 13.5 0.0 3 7.1 0.0 3.2 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 KND86661.1 - 0.17 11.6 0.9 28 4.4 0.0 3.2 1 1 2 3 3 3 0 TUP1-like enhancer of split TMEM234 PF10639.9 KND86662.1 - 8.6e-33 112.8 0.1 1.9e-32 111.7 0.1 1.5 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 KND86662.1 - 0.00064 19.9 6.5 0.092 12.9 4.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Methyltransf_34 PF11312.8 KND86663.1 - 2.8e-111 371.6 0.0 3.4e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Transketolase_N PF00456.21 KND86664.1 - 5e-160 531.9 0.0 6.5e-160 531.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KND86664.1 - 1.7e-45 154.9 0.0 2.6e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KND86664.1 - 6.5e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KND86664.1 - 0.0024 17.1 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KND86664.1 - 0.062 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component UDPG_MGDP_dh_N PF03721.14 KND86664.1 - 0.17 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiP_synth PF10120.9 KND86664.1 - 0.18 11.4 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Thiamine-phosphate synthase ATP-synt_C PF00137.21 KND86665.1 - 1.8e-30 105.1 33.5 6.4e-16 58.4 9.0 3.1 3 0 0 3 3 3 3 ATP synthase subunit C DUF2970 PF11174.8 KND86665.1 - 5.3 7.0 7.9 4.1 7.3 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Syja_N PF02383.18 KND86666.1 - 1.4e-94 317.0 0.0 1.9e-94 316.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KND86666.1 - 7.1e-40 135.3 0.0 1.3e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase PLDc PF00614.22 KND86667.1 - 2.5e-17 62.2 0.4 4.2e-08 33.0 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KND86667.1 - 2e-12 47.2 0.0 2.2e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KND86667.1 - 5.4e-06 26.4 0.2 5.5e-05 23.1 0.0 2.8 2 1 0 2 2 2 1 PX domain ERG4_ERG24 PF01222.17 KND86668.1 - 6e-138 460.2 23.6 6.9e-138 460.0 23.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Plus-3 PF03126.18 KND86669.1 - 7.5e-24 84.4 0.0 2.3e-23 82.8 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain COQ7 PF03232.13 KND86670.1 - 4.3e-69 231.7 0.4 5.9e-69 231.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 KND86670.1 - 0.0027 18.1 0.0 0.0061 17.0 0.0 1.6 2 1 0 2 2 2 1 Rubrerythrin Hydin_ADK PF17213.3 KND86670.1 - 0.069 13.4 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF724 PF05266.14 KND86670.1 - 0.18 11.6 0.4 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Fungal_trans PF04082.18 KND86671.1 - 7.3e-33 113.7 0.2 1.3e-32 112.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86671.1 - 1.6e-10 40.9 11.2 4.4e-10 39.5 11.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KND86671.1 - 0.13 12.4 1.6 0.22 11.6 0.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor GDPD PF03009.17 KND86672.1 - 3.7e-25 89.1 0.0 6.4e-19 68.7 0.0 2.5 1 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family G-alpha PF00503.20 KND86673.1 - 1.1e-111 373.5 0.2 1.3e-111 373.2 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KND86673.1 - 1.6e-13 50.5 1.5 2.9e-08 33.3 0.0 2.6 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND86673.1 - 0.00014 21.3 0.2 0.06 12.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KND86673.1 - 0.0046 17.2 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KND86673.1 - 0.039 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KND86673.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family F-box-like PF12937.7 KND86674.1 - 1e-05 25.3 0.5 1e-05 25.3 0.5 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KND86674.1 - 3.5e-05 23.6 0.8 3.5e-05 23.6 0.8 2.7 3 0 0 3 3 3 1 F-box domain TPR_2 PF07719.17 KND86674.1 - 0.00087 19.2 1.2 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PRANC PF09372.10 KND86674.1 - 0.09 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 PRANC domain TPR_11 PF13414.6 KND86674.1 - 0.09 12.5 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KND86674.1 - 0.091 12.6 0.7 3.5 7.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.7 KND86674.1 - 0.34 11.4 10.0 4.4 7.9 0.2 4.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) SET PF00856.28 KND86675.1 - 0.003 18.0 0.0 0.0052 17.2 0.0 1.5 1 1 0 1 1 1 1 SET domain MCD_N PF17408.2 KND86675.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain MMR_HSR1_C PF08438.10 KND86676.1 - 3.4e-37 127.4 0.0 7.2e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KND86676.1 - 9.3e-21 74.0 0.0 3e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND86676.1 - 4.5e-09 36.0 0.1 1.3e-07 31.3 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KND86676.1 - 0.0024 17.4 0.1 1.1 8.7 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KND86676.1 - 0.011 15.8 0.6 0.16 12.0 0.2 2.7 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 KND86676.1 - 0.11 12.4 0.4 14 5.5 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Ploopntkinase3 PF18751.1 KND86676.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KND86676.1 - 0.12 12.9 0.0 0.53 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MDH PF02315.16 KND86676.1 - 0.15 12.2 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit ATP_bind_1 PF03029.17 KND86676.1 - 0.2 11.4 0.1 7.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FHA PF00498.26 KND86678.1 - 1.2e-14 54.3 0.0 2.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND86678.1 - 0.0037 17.5 0.1 0.0099 16.2 0.0 1.7 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KND86678.1 - 0.0045 17.2 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.16 KND86679.1 - 1.5e-29 103.0 31.8 1.5e-29 103.0 31.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86679.1 - 5.2e-13 48.7 10.5 5.2e-13 48.7 10.5 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter Trypan_PARP PF05887.11 KND86679.1 - 0.00057 19.9 14.8 0.00057 19.9 14.8 2.1 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 KND86679.1 - 0.0053 17.3 21.9 0.0096 16.4 21.9 1.3 1 0 0 1 1 1 1 TonB polyproline region Sox_N PF12444.8 KND86679.1 - 0.013 16.6 0.0 0.023 15.8 0.0 1.3 1 0 0 1 1 1 0 Sox developmental protein N terminal Pex14_N PF04695.13 KND86679.1 - 0.18 12.5 13.4 0.51 11.0 13.4 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 KND86679.1 - 2.2 6.9 9.5 0.1 11.2 0.4 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF2868 PF11067.8 KND86679.1 - 2.5 7.6 9.6 0.28 10.7 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Thymidylat_synt PF00303.19 KND86680.1 - 1.2e-106 355.7 0.0 1.4e-106 355.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase IFRD PF05004.13 KND86681.1 - 1e-54 185.8 0.4 1.5e-54 185.2 0.4 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) BRICHOS PF04089.14 KND86681.1 - 0.042 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 BRICHOS domain DUF4259 PF14078.6 KND86681.1 - 0.12 13.1 3.4 0.27 12.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Btz PF09405.10 KND86683.1 - 7.6e-26 90.9 2.2 1.7e-25 89.7 2.2 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding DUF5308 PF17233.2 KND86684.1 - 1e-51 175.5 13.6 4.3e-49 166.9 13.6 2.0 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Ran_BP1 PF00638.18 KND86685.1 - 6.9e-11 42.5 0.0 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 KND86685.1 - 0.0057 17.5 14.3 0.0057 17.5 14.3 11.1 3 2 6 9 9 9 3 Nucleoporin FG repeat region N_BRCA1_IG PF16158.5 KND86686.1 - 1.2e-34 119.0 0.0 3.4e-34 117.6 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KND86686.1 - 7.5e-18 64.1 65.2 4.6e-06 26.3 8.1 4.7 4 1 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KND86686.1 - 0.024 14.9 10.0 0.024 14.9 10.0 4.6 4 0 0 4 4 4 0 C1 domain DUF5356 PF17309.2 KND86686.1 - 2 8.4 8.2 0.091 12.7 2.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5356) CBS PF00571.28 KND86687.1 - 8e-29 99.9 9.2 1.7e-10 41.2 0.2 4.3 4 0 0 4 4 4 4 CBS domain NDUFA12 PF05071.16 KND86688.1 - 4.8e-26 91.4 0.1 5.1e-26 91.4 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KND86689.1 - 8.6e-13 48.3 0.0 8.5e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KND86689.1 - 5.5e-05 23.2 4.2 0.034 14.3 0.6 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif An_peroxidase PF03098.15 KND86690.1 - 1.5e-31 109.6 0.0 1.1e-24 86.9 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KND86690.1 - 2.7e-07 29.7 0.0 5.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 KND86691.1 - 5.2e-07 28.7 0.2 0.0035 16.1 0.1 2.8 3 0 0 3 3 3 2 Transferase family Glyco_hydro_18 PF00704.28 KND86692.1 - 1.3e-19 71.1 2.0 7.6e-19 68.6 2.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 KND86692.1 - 1.9e-09 37.3 16.4 7.4e-09 35.4 16.4 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2235 PF09994.9 KND86693.1 - 2.6e-85 286.3 0.1 3.4e-85 285.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Alb1 PF09135.11 KND86694.1 - 9.1e-30 103.6 10.5 1.4e-29 103.1 10.5 1.3 1 0 0 1 1 1 1 Alb1 Amidase PF01425.21 KND86695.1 - 5.1e-18 65.3 0.0 7.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Amidase 2-Hacid_dh_C PF02826.19 KND86696.1 - 5.5e-36 123.6 0.0 6.5e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KND86696.1 - 1.5e-05 25.2 0.0 3.9e-05 23.9 0.0 1.6 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND86696.1 - 0.033 14.8 0.1 0.09 13.4 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KND86696.1 - 0.099 12.9 0.1 0.59 10.4 0.0 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HAT_KAT11 PF08214.11 KND86697.1 - 2.5e-92 309.9 0.0 3.1e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein MFS_1 PF07690.16 KND86698.1 - 3.5e-28 98.6 33.7 7.8e-28 97.4 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KND86699.1 - 2.5e-15 56.2 9.4 3.5e-15 55.7 9.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86699.1 - 2.6e-07 30.7 8.6 4.8e-07 29.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NYD-SP28_assoc PF14775.6 KND86699.1 - 0.089 12.9 0.8 0.29 11.3 0.8 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain Amidase PF01425.21 KND86700.1 - 1.6e-84 284.5 0.0 5.1e-84 282.8 0.0 1.8 2 0 0 2 2 2 1 Amidase Ras PF00071.22 KND86702.1 - 1.6e-31 109.1 0.2 1.9e-31 108.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND86702.1 - 5.5e-24 84.7 0.1 8.4e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND86702.1 - 2e-06 27.4 0.1 2.7e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND86702.1 - 0.00052 19.4 0.2 0.00068 19.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KND86702.1 - 0.0025 16.7 0.0 0.4 9.4 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) PLAC8 PF04749.17 KND86704.1 - 5e-08 33.9 2.0 9.4e-08 33.0 2.0 1.4 1 0 0 1 1 1 1 PLAC8 family zf-NF-X1 PF01422.17 KND86705.1 - 0.064 13.3 4.4 0.064 13.3 4.4 2.2 2 0 0 2 2 2 0 NF-X1 type zinc finger PNTB PF02233.16 KND86706.1 - 1e-170 568.7 23.1 1e-170 568.7 23.1 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KND86706.1 - 9.9e-73 244.0 0.2 9.9e-73 244.0 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KND86706.1 - 1.4e-48 164.7 0.4 8.1e-48 162.2 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KND86706.1 - 2.5e-29 101.5 3.4 2.5e-29 101.5 3.4 5.7 3 1 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KND86706.1 - 0.00067 19.1 1.8 0.17 11.2 0.1 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 KND86706.1 - 0.017 15.1 0.2 0.069 13.1 0.2 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KND86706.1 - 0.017 14.4 0.1 0.041 13.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 KND86706.1 - 0.053 13.7 3.1 0.95 9.6 0.8 3.1 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fumerase PF05681.14 KND86706.1 - 0.086 12.3 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) GIDA PF01134.22 KND86706.1 - 0.16 11.0 0.5 0.27 10.3 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KND86706.1 - 5.9 7.2 8.5 0.29 11.4 1.3 2.8 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GCV_H PF01597.19 KND86707.1 - 1.4e-30 105.7 0.4 1.8e-30 105.4 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein GvpO PF05800.11 KND86707.1 - 0.11 12.5 0.2 0.28 11.2 0.1 1.8 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpO Porphobil_deam PF01379.20 KND86708.1 - 1.1e-76 256.9 0.1 1.9e-76 256.1 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KND86708.1 - 4.6e-18 65.4 0.9 1.4e-17 63.8 0.4 2.0 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain SesA PF17107.5 KND86709.1 - 9.9e-13 48.3 1.6 1.6e-12 47.7 1.6 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases VCBS PF13517.6 KND86709.1 - 1.5e-09 38.3 8.7 1.2e-05 25.8 1.4 3.7 1 1 4 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Polyoma_lg_T_C PF06431.11 KND86709.1 - 0.0052 15.7 0.1 0.0077 15.2 0.1 1.2 1 0 0 1 1 1 1 Polyomavirus large T antigen C-terminus ATG101 PF07855.12 KND86709.1 - 0.089 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein 101 PBP PF01161.20 KND86710.1 - 8.2e-08 32.6 0.0 1.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PvlArgDC PF01862.16 KND86710.1 - 0.21 11.4 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Ribosomal_L4 PF00573.22 KND86711.1 - 1.6e-44 151.9 0.0 2.2e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family bZIP_1 PF00170.21 KND86712.1 - 7.4e-09 35.6 3.0 1.3e-08 34.8 3.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KND86712.1 - 3.4e-07 30.7 2.2 5.8e-07 29.9 2.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KND86712.1 - 4.4e-07 29.9 1.0 7.6e-07 29.1 1.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper RhoGAP PF00620.27 KND86713.1 - 3e-07 30.4 0.0 5.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Rep_fac-A_3 PF08661.11 KND86714.1 - 2.8e-07 30.8 0.0 5.7e-07 29.8 0.0 1.5 2 0 0 2 2 2 1 Replication factor A protein 3 Arm PF00514.23 KND86716.1 - 2.1e-76 249.9 32.8 1.5e-13 50.2 0.1 11.2 11 0 0 11 11 11 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KND86716.1 - 9.5e-20 70.7 11.7 6.2e-05 23.4 0.2 8.3 7 2 2 9 9 9 4 HEAT-like repeat HEAT_2 PF13646.6 KND86716.1 - 8.7e-18 64.5 8.8 0.00015 22.1 0.1 6.9 3 3 3 7 7 7 5 HEAT repeats HEAT PF02985.22 KND86716.1 - 1.5e-15 55.9 15.8 0.058 13.7 0.2 8.6 10 0 0 10 10 8 5 HEAT repeat Adaptin_N PF01602.20 KND86716.1 - 1.1e-12 47.4 7.3 1.5e-07 30.4 0.3 2.7 1 1 0 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KND86716.1 - 9.5e-11 41.6 6.3 1.8e-07 30.9 1.7 2.8 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 KND86716.1 - 2e-09 36.2 0.8 3.6e-09 35.4 0.8 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KND86716.1 - 4.7e-09 36.0 1.5 1.3e-05 24.6 0.9 2.7 1 1 1 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 KND86716.1 - 8.4e-05 22.7 0.4 17 5.6 0.0 4.9 2 1 5 7 7 7 0 V-ATPase subunit H Cnd1 PF12717.7 KND86716.1 - 0.00014 22.0 8.3 0.12 12.4 0.3 4.8 1 1 5 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KND86716.1 - 0.0002 20.9 5.2 1 8.7 0.4 4.6 2 2 3 5 5 5 2 Family of unknown function (DUF5578) IFRD PF05004.13 KND86716.1 - 0.00082 18.6 2.5 1.6 7.8 0.1 3.9 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KND86716.1 - 0.018 15.0 1.8 1.5 8.8 0.1 3.3 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 KND86716.1 - 0.019 15.6 7.5 37 5.4 0.2 6.8 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KND86716.1 - 0.072 13.7 0.2 4.9 7.8 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 KND86716.1 - 0.14 12.2 6.5 5.2 7.2 0.3 4.2 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain UQ_con PF00179.26 KND86717.1 - 1.5e-50 170.5 0.1 1.7e-50 170.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND86717.1 - 0.0002 21.1 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND86717.1 - 0.03 14.6 1.8 0.066 13.5 1.8 1.7 1 1 0 1 1 1 0 RWD domain SCAB_CC PF16712.5 KND86718.1 - 0.075 12.9 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Pex19 PF04614.12 KND86719.1 - 3.7e-73 246.3 14.1 3.7e-73 246.3 14.1 1.7 2 0 0 2 2 2 1 Pex19 protein family ApoLp-III PF07464.11 KND86719.1 - 0.0061 16.7 0.3 1.7 8.7 0.1 2.4 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) ABC1 PF03109.16 KND86720.1 - 2.7e-33 114.6 0.0 4.7e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DnaJ PF00226.31 KND86721.1 - 7.4e-10 38.8 0.1 1.4e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 KND86722.1 - 7.4e-65 219.1 8.1 4.8e-55 186.9 3.3 2.0 2 0 0 2 2 2 2 Eukaryotic porin Asn_synthase PF00733.21 KND86723.1 - 1.8e-89 300.9 0.0 1.7e-53 182.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KND86723.1 - 1.1e-37 128.6 0.0 1.8e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KND86723.1 - 4.1e-29 101.5 0.0 7e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KND86723.1 - 6.5e-08 32.3 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KND86723.1 - 0.00095 18.4 0.0 0.0024 17.0 0.0 1.7 1 1 0 1 1 1 1 NAD synthase IF3_C PF00707.22 KND86724.1 - 2.6e-09 36.9 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KND86724.1 - 0.00048 19.8 0.0 0.00085 19.0 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.16 KND86724.1 - 0.073 13.3 0.4 0.33 11.2 0.4 1.9 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain Peptidase_S26 PF10502.9 KND86725.1 - 2.7e-05 24.0 0.0 0.00062 19.6 0.0 2.3 2 1 0 2 2 2 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KND86725.1 - 0.00013 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_M14 PF00246.24 KND86726.1 - 1.6e-82 277.6 0.0 1.9e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Thymidylate_kin PF02223.17 KND86727.1 - 2.5e-41 141.4 0.0 4.4e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KND86727.1 - 0.00017 21.9 0.0 0.0003 21.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 KND86727.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 KND86727.1 - 0.05 14.1 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 KND86727.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arf PF00025.21 KND86727.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family OPT PF03169.15 KND86728.1 - 2e-171 571.8 48.8 2.3e-171 571.6 48.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KND86728.1 - 0.77 9.1 3.2 0.44 9.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Formyl_trans_N PF00551.19 KND86729.1 - 3e-38 131.4 0.1 4e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 KND86729.1 - 5.7e-09 35.6 0.0 1.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KND86729.1 - 4.1e-05 23.5 0.3 0.0002 21.3 0.0 2.2 2 1 1 3 3 3 1 ACT domain ZnuA PF01297.17 KND86729.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic SRP54 PF00448.22 KND86730.1 - 4e-77 258.3 1.0 4e-77 258.3 1.0 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KND86730.1 - 5.7e-31 107.1 5.6 5.7e-31 107.1 5.6 3.8 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KND86730.1 - 9.4e-21 73.8 0.6 2.4e-20 72.5 0.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KND86730.1 - 3.5e-07 30.0 0.9 2.3e-06 27.3 0.9 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KND86730.1 - 3.2e-06 27.4 0.0 8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND86730.1 - 1.9e-05 25.1 0.0 4.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KND86730.1 - 6.4e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KND86730.1 - 0.00018 20.6 0.4 0.0014 17.7 0.4 2.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 KND86730.1 - 0.00023 21.6 1.7 0.00037 20.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND86730.1 - 0.0015 18.3 1.0 0.0032 17.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KND86730.1 - 0.002 18.2 0.0 0.0079 16.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 KND86730.1 - 0.0035 17.3 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Fe-ADH PF00465.19 KND86730.1 - 0.0041 16.0 0.0 0.0085 15.0 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Thymidylate_kin PF02223.17 KND86730.1 - 0.0046 16.7 0.2 0.033 13.9 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase ResIII PF04851.15 KND86730.1 - 0.0047 17.0 0.4 0.13 12.3 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.6 KND86730.1 - 0.005 17.1 0.1 0.0097 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND86730.1 - 0.0053 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KND86730.1 - 0.0068 16.5 0.2 0.18 11.9 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 KND86730.1 - 0.0084 15.6 0.3 2.6 7.5 0.1 3.1 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KND86730.1 - 0.0084 15.9 0.3 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KND86730.1 - 0.0085 16.4 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 KND86730.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 Torsin NTPase_1 PF03266.15 KND86730.1 - 0.014 15.3 1.5 1.3 8.9 1.5 2.4 1 1 0 1 1 1 0 NTPase 6PF2K PF01591.18 KND86730.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 KND86730.1 - 0.021 14.7 0.1 0.098 12.6 0.0 2.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 KND86730.1 - 0.025 14.9 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND86730.1 - 0.12 12.1 0.8 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KND86730.1 - 0.13 12.7 0.3 0.55 10.7 0.3 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKA2 PF16740.5 KND86730.1 - 0.14 12.0 3.7 6.6 6.6 1.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Methyltransf_24 PF13578.6 KND86730.1 - 0.16 13.0 0.0 0.37 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 KND86731.1 - 7.3e-10 38.3 0.6 3.3e-09 36.2 0.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C58 PF03543.14 KND86731.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen adh_short_C2 PF13561.6 KND86732.1 - 2.3e-57 194.3 0.2 2.7e-57 194.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND86732.1 - 4.1e-47 160.2 0.3 4.8e-47 160.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND86732.1 - 3.6e-12 46.6 0.6 5e-12 46.1 0.6 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 KND86732.1 - 0.013 15.5 0.8 0.026 14.6 0.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 KND86732.1 - 0.05 12.9 0.5 0.07 12.4 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KND86732.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KND86732.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PepX_C PF08530.10 KND86733.1 - 3.4e-13 50.1 0.0 1.8e-12 47.7 0.0 2.2 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 KND86733.1 - 2e-08 34.2 0.1 3.8e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FAM217 PF15344.6 KND86734.1 - 0.099 12.6 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 FAM217 family TPP_enzyme_N PF02776.18 KND86735.1 - 5.1e-23 81.5 0.0 3.3e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND86735.1 - 2.4e-20 72.6 0.0 4.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KND86735.1 - 8.7e-12 45.1 0.1 1.5e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_hydro_18 PF00704.28 KND86736.1 - 4e-09 36.7 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pyr_redox_2 PF07992.14 KND86737.1 - 5.2e-13 48.9 0.0 2.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND86737.1 - 0.0015 18.2 1.5 0.0043 16.7 0.5 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND86737.1 - 0.0024 17.9 0.0 0.039 13.9 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Malic_M PF03949.15 KND86737.1 - 0.069 12.4 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain FAD_binding_3 PF01494.19 KND86737.1 - 0.11 11.7 0.0 0.32 10.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KND86737.1 - 0.12 11.4 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B PF00753.27 KND86738.1 - 2.7e-17 63.4 4.2 4.7e-17 62.7 4.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KND86738.1 - 7.2e-06 25.6 0.8 1.6e-05 24.6 0.3 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF4141 PF13605.6 KND86738.1 - 0.029 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Lactamase_B_3 PF13483.6 KND86738.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L14 PF00238.19 KND86739.1 - 2.8e-45 153.3 2.4 3.3e-45 153.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.18 KND86740.1 - 3.4e-16 58.8 4.8 3.4e-16 58.8 4.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KND86740.1 - 1.6e-12 47.1 2.8 1.6e-12 47.1 2.8 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 KND86740.1 - 0.0078 16.1 10.1 0.054 13.4 1.0 3.3 3 0 0 3 3 3 2 Nudix N-terminal Lar_restr_allev PF14354.6 KND86740.1 - 0.064 13.6 2.7 0.064 13.6 2.7 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_10 PF10058.9 KND86740.1 - 0.13 12.0 11.3 0.4 10.4 0.4 3.0 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 KND86740.1 - 0.17 11.9 15.2 0.25 11.4 2.7 2.5 2 1 0 2 2 2 0 Double zinc ribbon Pkinase_Tyr PF07714.17 KND86741.1 - 1.1e-17 64.2 0.0 5.8e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND86741.1 - 7.2e-15 55.1 0.0 9.9e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PSI_PSAK PF01241.18 KND86741.1 - 0.00038 20.4 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 2 Photosystem I psaG / psaK Kdo PF06293.14 KND86741.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP2_3 PF14378.6 KND86742.1 - 1.7e-26 93.1 13.7 9.7e-20 71.1 2.5 2.5 3 0 0 3 3 3 2 PAP2 superfamily DUF2537 PF10801.8 KND86742.1 - 0.019 15.2 0.8 0.019 15.2 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2537) PAP2_C PF14360.6 KND86742.1 - 0.027 15.0 5.6 0.14 12.7 0.2 2.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal SET PF00856.28 KND86743.1 - 4.8e-10 40.1 0.6 2.4e-09 37.8 0.0 2.5 3 1 0 3 3 3 1 SET domain FAM76 PF16046.5 KND86743.1 - 0.02 14.3 1.1 0.02 14.3 1.1 2.0 2 0 0 2 2 2 0 FAM76 protein SKG6 PF08693.10 KND86745.1 - 2.7e-07 29.9 0.8 2.7e-07 29.9 0.8 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain VSP PF03302.13 KND86745.1 - 0.0026 16.7 3.4 0.0026 16.7 3.4 2.3 1 1 1 2 2 2 1 Giardia variant-specific surface protein DUF202 PF02656.15 KND86745.1 - 0.021 15.3 2.0 0.024 15.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4381 PF14316.6 KND86745.1 - 0.027 14.7 0.2 0.044 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PseudoU_synth_1 PF01416.20 KND86746.1 - 8.1e-12 45.6 0.0 2e-09 37.8 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase UBM PF14377.6 KND86746.1 - 0.016 14.6 0.3 0.043 13.3 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Ank_2 PF12796.7 KND86748.1 - 3.3e-37 126.9 3.4 6.9e-16 58.6 0.0 4.8 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86748.1 - 1.5e-28 98.8 0.9 7e-11 42.4 0.0 6.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86748.1 - 4.8e-20 69.5 2.0 3.6e-05 23.8 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat NACHT_N PF17100.5 KND86748.1 - 3.4e-18 66.3 0.4 3.4e-18 66.3 0.4 1.9 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank PF00023.30 KND86748.1 - 1.3e-17 63.4 9.2 5.5e-05 23.4 0.0 9.0 7 2 2 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 KND86748.1 - 1.3e-17 63.6 7.7 2.4e-07 30.9 0.0 7.9 4 1 5 9 9 9 5 Ankyrin repeats (many copies) NACHT PF05729.12 KND86748.1 - 0.0097 15.8 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ssDNA_DBD PF18333.1 KND86748.1 - 0.1 12.7 1.9 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Non-canonical single-stranded DNA-binding domain Beta_elim_lyase PF01212.21 KND86750.1 - 5.4e-64 216.3 0.5 6.7e-64 216.0 0.5 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KND86750.1 - 0.0019 17.6 0.1 0.0028 17.0 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KND86750.1 - 0.097 11.2 0.1 0.22 10.0 0.1 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme APH PF01636.23 KND86751.1 - 9.1e-13 48.7 0.1 1.7e-12 47.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND86751.1 - 0.00027 20.3 0.0 0.00038 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KND86751.1 - 0.0016 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND86751.1 - 0.0046 16.6 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KND86751.1 - 0.012 14.9 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Med22 PF06179.12 KND86752.1 - 1.1e-20 73.8 0.0 1.4e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Shisa PF13908.6 KND86753.1 - 0.00064 20.0 2.0 0.00089 19.6 2.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.16 KND86753.1 - 0.002 18.3 0.1 0.0024 18.0 0.1 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Orf78 PF06024.12 KND86753.1 - 0.02 15.2 0.3 0.046 14.0 0.2 1.7 1 1 1 2 2 2 0 Orf78 (ac78) FAM195 PF14799.6 KND86753.1 - 0.023 15.0 0.1 0.05 13.9 0.1 1.5 1 0 0 1 1 1 0 FAM195 family DUF4199 PF13858.6 KND86753.1 - 0.056 13.8 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SDF PF00375.18 KND86753.1 - 0.059 12.4 0.2 0.061 12.3 0.2 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Tmemb_9 PF05434.11 KND86753.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 TMEM9 Mucin PF01456.17 KND86753.1 - 0.41 10.6 12.2 0.47 10.4 11.3 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF4834 PF16118.5 KND86753.1 - 0.47 11.5 1.5 0.68 10.9 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Protocadherin PF08374.11 KND86753.1 - 0.63 10.0 6.4 3.9 7.4 1.2 2.2 1 1 1 2 2 2 0 Protocadherin LIP PF03583.14 KND86754.1 - 0.054 12.8 0.0 0.06 12.7 0.0 1.0 1 0 0 1 1 1 0 Secretory lipase MFS_1 PF07690.16 KND86755.1 - 3.5e-23 82.1 35.5 3.5e-23 82.1 35.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86755.1 - 5e-14 52.0 14.9 5e-14 52.0 14.9 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 KND86756.1 - 5.3e-50 167.9 0.0 3.2e-08 34.0 0.0 7.0 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND86756.1 - 2.4e-38 130.0 0.1 0.0017 18.9 0.0 11.5 7 3 4 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND86756.1 - 1.2e-35 117.5 6.1 0.014 15.8 0.0 14.3 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 KND86756.1 - 5.4e-35 119.0 1.6 0.00064 20.0 0.1 9.9 7 3 3 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KND86756.1 - 1.5e-29 101.1 15.2 0.014 15.9 0.0 13.5 13 1 1 14 14 14 6 Ankyrin repeat FCD PF07729.12 KND86756.1 - 0.0061 17.0 0.1 15 6.0 0.0 4.5 5 1 1 6 6 6 1 FCD domain MOZART1 PF12554.8 KND86756.1 - 0.039 13.7 0.4 30 4.5 0.0 4.7 6 0 0 6 6 6 0 Mitotic-spindle organizing gamma-tubulin ring associated RVT_2 PF07727.14 KND86757.1 - 0.00071 19.3 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PI-PLC-C1 PF16670.5 KND86761.1 - 7.2e-124 413.1 0.0 8.2e-124 412.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent Abhydrolase_6 PF12697.7 KND86764.1 - 9.2e-07 29.7 0.0 1.5e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND86764.1 - 5.9e-06 25.7 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND86764.1 - 0.00022 21.0 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KND86764.1 - 0.0024 17.9 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Sugar_tr PF00083.24 KND86765.1 - 1.5e-79 268.0 24.1 9.7e-55 186.2 3.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND86765.1 - 1.4e-18 66.9 58.0 1.3e-12 47.4 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AsnC_trans_reg2 PF17805.1 KND86765.1 - 0.17 12.1 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 AsnC-like ligand binding domain TAL_FSA PF00923.19 KND86766.1 - 3.7e-30 105.3 0.0 5.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Beta-lactamase PF00144.24 KND86767.1 - 6.2e-47 160.5 0.1 9.2e-47 159.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KND86767.1 - 0.00026 21.4 0.0 0.00051 20.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Acetyltransf_10 PF13673.7 KND86768.1 - 5.1e-12 45.8 0.0 6.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND86768.1 - 5e-11 42.9 0.0 9.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND86768.1 - 7.3e-11 42.3 0.0 9.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KND86768.1 - 6.3e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND86768.1 - 7.7e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KND86768.1 - 0.0019 18.4 0.0 0.0024 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 KND86769.1 - 3.3e-31 108.5 37.5 4.7e-31 108.0 37.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND86769.1 - 2.5e-07 29.9 22.6 8.7e-07 28.1 22.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter G0-G1_switch_2 PF15103.6 KND86769.1 - 0.094 13.1 2.5 1.5 9.3 0.1 2.9 3 0 0 3 3 3 0 G0/G1 switch protein 2 Bestrophin PF01062.21 KND86770.1 - 1.5e-36 126.3 0.1 4.3e-36 124.8 0.1 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glyoxalase PF00903.25 KND86772.1 - 4.8e-06 26.8 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_M28 PF04389.17 KND86773.1 - 2.8e-31 108.8 0.0 4.6e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Rotamase PF00639.21 KND86773.1 - 2.2e-20 73.4 0.0 5.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KND86773.1 - 4.2e-14 53.1 0.0 8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain PA PF02225.22 KND86773.1 - 2.4e-09 37.1 0.2 6.2e-09 35.8 0.2 1.7 1 0 0 1 1 1 1 PA domain WW PF00397.26 KND86773.1 - 2.8e-06 27.3 1.0 9.2e-06 25.7 1.0 2.0 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 KND86773.1 - 0.00092 20.0 0.0 0.0019 19.0 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Peptidase_M20 PF01546.28 KND86773.1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 LrgB PF04172.16 KND86774.1 - 5.9e-23 81.5 12.7 4.9e-15 55.6 3.6 2.9 2 0 0 2 2 2 2 LrgB-like family CrgA PF06781.12 KND86774.1 - 0.8 9.8 3.4 4.3 7.5 3.4 2.3 1 0 0 1 1 1 0 Cell division protein CrgA SE PF08491.10 KND86775.1 - 2e-92 309.1 0.0 2.5e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KND86775.1 - 1.3e-14 54.2 0.0 1.8e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND86775.1 - 4.2e-09 36.4 0.3 3.8e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KND86775.1 - 7.7e-05 21.9 0.1 0.054 12.6 0.1 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KND86775.1 - 0.00017 21.7 0.5 0.00034 20.8 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KND86775.1 - 0.00031 20.2 0.1 0.00049 19.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND86775.1 - 0.00073 20.0 0.1 0.013 16.1 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KND86775.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KND86775.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 KND86775.1 - 0.0037 16.5 0.2 0.011 15.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 KND86775.1 - 0.0051 16.1 0.7 0.019 14.2 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KND86775.1 - 0.0068 16.5 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KND86775.1 - 0.016 14.3 2.3 0.017 14.2 0.7 1.8 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KND86775.1 - 0.03 13.2 0.1 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KND86775.1 - 0.035 13.8 0.1 0.069 12.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KND86775.1 - 0.057 12.5 0.2 0.13 11.2 0.2 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.25 KND86775.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase HI0933_like PF03486.14 KND86775.1 - 0.14 10.9 0.1 0.23 10.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.17 KND86775.1 - 0.18 12.4 0.1 0.43 11.2 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 KND86775.1 - 0.2 10.9 0.2 0.39 10.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 KND86776.1 - 9.1e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND86776.1 - 9.8e-08 31.6 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KND86776.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND86776.1 - 3.1e-05 24.0 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND86776.1 - 0.00087 18.2 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KND86776.1 - 0.0049 16.5 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KND86776.1 - 0.0072 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KND86776.1 - 0.063 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.11 KND86776.1 - 0.15 11.1 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 KND86776.1 - 0.17 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1192 PF06698.11 KND86777.1 - 0.038 14.1 2.4 0.26 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4972 PF16342.5 KND86777.1 - 0.041 13.6 3.5 0.086 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) DUF501 PF04417.12 KND86777.1 - 0.076 12.8 4.1 0.22 11.3 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Ist1 PF03398.14 KND86777.1 - 0.97 9.3 8.7 0.26 11.2 0.9 2.9 3 0 0 3 3 3 0 Regulator of Vps4 activity in the MVB pathway MbeD_MobD PF04899.12 KND86777.1 - 3.9 7.7 8.9 6.6 6.9 0.7 4.1 3 1 1 4 4 4 0 MbeD/MobD like AAA_13 PF13166.6 KND86778.1 - 0.02 13.6 2.3 0.025 13.3 2.3 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.14 KND86778.1 - 0.23 11.8 5.9 0.41 11.0 5.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APH PF01636.23 KND86779.1 - 3.1e-05 24.0 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KND86780.1 - 5.7e-10 39.5 0.0 7.9e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND86780.1 - 0.02 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EBP PF05241.12 KND86781.1 - 1.2e-59 200.8 10.5 1.4e-59 200.5 10.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein Glyco_hydro_31 PF01055.26 KND86782.1 - 1.8e-76 258.1 0.0 2.2e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KND86782.1 - 1.6e-06 28.3 0.0 4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like p450 PF00067.22 KND86783.1 - 2.6e-36 125.4 0.0 9.4e-26 90.6 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Maff2 PF12750.7 KND86784.1 - 0.085 12.7 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Maff2 family MFS_1 PF07690.16 KND86785.1 - 3.7e-31 108.3 30.5 3.7e-31 108.3 30.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily PspB PF06667.12 KND86785.1 - 0.053 13.6 0.2 0.053 13.6 0.2 2.3 2 0 0 2 2 2 0 Phage shock protein B DUF2614 PF11023.8 KND86785.1 - 0.17 12.0 2.1 1.4 9.0 0.5 2.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain UPF0242 PF06785.11 KND86787.1 - 0.62 10.1 30.5 0.5 10.4 8.6 4.0 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 KND86787.1 - 4 7.8 7.4 0.38 11.0 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Mpv17_PMP22 PF04117.12 KND86788.1 - 6.4e-15 55.1 0.4 6.4e-15 55.1 0.4 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family NAD_binding_2 PF03446.15 KND86789.1 - 3.4e-27 95.5 0.5 5.3e-27 94.9 0.5 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KND86789.1 - 3.3e-08 33.8 0.2 6.1e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KND86789.1 - 3.2e-06 27.6 0.0 9.1e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KND86789.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 KND86790.1 - 3.4e-06 26.3 0.0 5.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86790.1 - 0.12 12.5 5.4 0.47 10.6 5.4 2.1 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.21 KND86791.1 - 1.4e-07 30.7 0.2 2e-07 30.1 0.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KND86791.1 - 0.0062 16.6 0.0 0.049 13.7 0.1 2.2 2 0 0 2 2 2 1 YrhC-like protein DNA_pol_A_exo1 PF01612.20 KND86793.1 - 6.2e-42 143.3 0.1 9.1e-42 142.7 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KND86793.1 - 4.1e-26 91.5 0.1 8.7e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KND86793.1 - 2.6e-08 33.8 0.0 6.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Glyco_transf_20 PF00982.21 KND86794.1 - 1.4e-198 660.4 0.0 1.7e-198 660.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 KND86794.1 - 0.042 13.5 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain TFIID_20kDa PF03847.13 KND86795.1 - 1.1e-18 67.5 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 KND86795.1 - 0.022 14.8 0.2 0.39 10.8 0.0 2.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Rpn3_C PF08375.11 KND86796.1 - 6.1e-26 90.6 1.7 1.8e-25 89.1 1.7 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KND86796.1 - 9.2e-20 71.1 0.1 2.3e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KND86796.1 - 0.016 15.3 1.6 0.025 14.7 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 KND86797.1 - 5.8e-13 47.8 0.8 0.11 12.7 0.0 6.7 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KND86797.1 - 0.025 15.1 0.2 42 5.2 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat VID27 PF08553.10 KND86798.1 - 6.8e-192 637.2 0.1 8.7e-192 636.8 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KND86798.1 - 2.9e-73 245.4 0.7 2.9e-73 245.4 0.7 3.8 4 0 0 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 KND86798.1 - 3.6e-42 143.1 0.5 8e-42 142.0 0.5 1.6 1 0 0 1 1 1 1 VID27 PH-like domain DNA_pol_phi PF04931.13 KND86798.1 - 0.18 9.9 7.8 0.28 9.2 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RTA1 PF04479.13 KND86799.1 - 1e-13 51.4 2.7 1e-13 51.4 2.7 1.7 2 0 0 2 2 2 1 RTA1 like protein Cupin_1 PF00190.22 KND86800.1 - 1.1e-17 64.1 0.7 2.2e-17 63.1 0.7 1.4 1 0 0 1 1 1 1 Cupin Ank_2 PF12796.7 KND86800.1 - 1.4e-16 60.9 0.4 7.7e-09 36.0 1.7 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND86800.1 - 7.3e-12 44.4 1.4 0.0046 17.4 0.0 4.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KND86800.1 - 2.5e-11 43.8 5.1 2.5e-05 24.7 0.5 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND86800.1 - 9.7e-11 41.7 6.2 9.8e-05 22.6 0.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KND86800.1 - 1.4e-10 41.1 5.7 0.021 15.3 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Cupin_2 PF07883.11 KND86800.1 - 0.00052 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Ribosomal_S26e PF01283.19 KND86802.1 - 3e-50 169.1 9.2 3.5e-50 168.9 9.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KND86802.1 - 0.03 14.3 0.3 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 KND86802.1 - 1.5 8.6 6.6 0.24 11.2 1.5 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4668) Ribosomal_S27 PF01599.19 KND86803.1 - 1.6e-26 92.2 1.3 1.6e-26 92.2 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 KND86803.1 - 0.054 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Nop PF01798.18 KND86804.1 - 3.2e-81 272.2 0.1 3.2e-81 272.2 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KND86804.1 - 3.6e-18 65.7 0.2 3.6e-18 65.7 0.2 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RR_TM4-6 PF06459.12 KND86804.1 - 1.6 8.5 12.5 3.1 7.5 12.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KND86804.1 - 6.1 6.9 24.6 10 6.1 24.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Glyco_hydro_18 PF00704.28 KND86805.1 - 6.1e-86 289.0 1.5 7e-86 288.8 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SepF PF04472.12 KND86805.1 - 0.24 11.7 0.0 9.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Cell division protein SepF BcrAD_BadFG PF01869.20 KND86806.1 - 5.2e-18 65.5 1.7 5.3e-18 65.5 0.3 1.7 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.22 KND86806.1 - 0.0021 17.9 0.4 0.034 14.0 0.0 2.7 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 KND86806.1 - 0.0039 17.2 0.7 0.64 10.0 0.1 4.0 3 1 0 3 3 3 1 SIS domain PAN_4 PF14295.6 KND86806.1 - 0.39 10.7 1.9 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 PAN domain UNC-93 PF05978.16 KND86807.1 - 1.2e-09 38.1 5.1 1.2e-09 38.1 5.1 2.2 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KND86807.1 - 4.7e-07 29.0 39.9 4.7e-07 29.0 39.9 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily EXS PF03124.14 KND86807.1 - 0.0059 16.0 2.4 0.0059 16.0 2.4 2.0 2 0 0 2 2 2 1 EXS family LapA_dom PF06305.11 KND86807.1 - 0.093 12.6 4.0 0.45 10.4 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain ELYS PF13934.6 KND86808.1 - 3.9e-65 219.9 1.2 4.7e-65 219.6 1.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly ATP-synt_C PF00137.21 KND86809.1 - 4.1e-10 39.9 12.2 4.1e-10 39.9 12.2 1.7 2 0 0 2 2 2 1 ATP synthase subunit C Phage_holin_3_6 PF07332.11 KND86809.1 - 0.014 15.5 1.7 0.022 14.8 1.7 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MOZ_SAS PF01853.18 KND86810.1 - 1.7e-52 177.6 0.0 2.7e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KND86810.1 - 2.5e-09 36.6 0.2 0.0023 17.5 0.2 2.3 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 KND86810.1 - 0.018 15.5 0.0 0.56 10.7 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND86810.1 - 0.15 12.3 0.0 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family SnoaL_4 PF13577.6 KND86810.1 - 0.26 11.4 1.3 6.7 6.9 0.2 2.3 2 0 0 2 2 2 0 SnoaL-like domain APH PF01636.23 KND86811.1 - 0.061 13.2 0.0 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family CENP-R PF06729.12 KND86812.1 - 0.44 10.5 3.8 0.7 9.8 2.5 2.0 1 1 0 1 1 1 0 Kinetochore component, CENP-R Arginase PF00491.21 KND86813.1 - 1.2e-75 254.6 0.4 1.4e-75 254.4 0.4 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 KND86815.1 - 0.0019 18.2 10.3 0.0055 16.7 10.2 1.9 1 1 1 2 2 2 1 Membrane-associating domain Amidohydro_1 PF01979.20 KND86816.1 - 7.2e-27 94.6 0.0 1.2e-26 93.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND86816.1 - 4.5e-12 46.2 0.3 6.4e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family SMC_N PF02463.19 KND86817.1 - 4.7e-35 121.0 9.3 8.3e-35 120.2 9.2 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND86817.1 - 3.1e-22 79.1 0.1 8.5e-22 77.7 0.0 1.8 2 0 0 2 2 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KND86817.1 - 1.9e-05 24.7 0.5 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 KND86817.1 - 4.4e-05 22.5 61.6 0.065 12.1 1.1 4.7 3 1 3 6 6 6 5 Spc7 kinetochore protein Fib_alpha PF08702.10 KND86817.1 - 0.00081 19.6 3.2 0.00081 19.6 3.2 5.1 4 1 1 5 5 5 1 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.11 KND86817.1 - 0.00081 18.4 25.3 0.00081 18.4 25.3 3.4 3 1 1 4 4 4 1 Calcium binding and coiled-coil domain (CALCOCO1) like IFT57 PF10498.9 KND86817.1 - 0.0011 18.1 8.7 0.0011 18.1 8.7 3.7 2 1 1 4 4 3 2 Intra-flagellar transport protein 57 GAS PF13851.6 KND86817.1 - 0.0018 17.6 4.6 0.0018 17.6 4.6 6.1 3 1 2 6 6 6 2 Growth-arrest specific micro-tubule binding Tektin PF03148.14 KND86817.1 - 0.0019 17.1 10.4 0.0019 17.1 10.4 4.2 2 2 2 4 4 4 1 Tektin family DUF4201 PF13870.6 KND86817.1 - 0.0026 17.5 13.9 0.0026 17.5 13.9 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF4201) DivIC PF04977.15 KND86817.1 - 0.0027 17.5 2.0 0.0027 17.5 2.0 7.6 5 2 6 11 11 8 1 Septum formation initiator MscS_porin PF12795.7 KND86817.1 - 0.0035 16.9 50.6 0.0097 15.5 12.0 4.3 3 1 1 4 4 4 3 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 KND86817.1 - 0.0038 17.3 68.9 0.021 14.9 6.9 6.6 3 2 3 7 7 7 2 TPR/MLP1/MLP2-like protein THOC7 PF05615.13 KND86817.1 - 0.012 15.9 4.4 0.012 15.9 4.4 6.5 3 2 2 5 5 3 0 Tho complex subunit 7 ATG16 PF08614.11 KND86817.1 - 0.012 15.8 8.4 0.012 15.8 8.4 5.8 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 KND86817.1 - 0.026 14.6 0.3 0.026 14.6 0.3 4.8 3 2 2 5 5 4 0 TolA binding protein trimerisation SbcCD_C PF13558.6 KND86817.1 - 0.031 14.5 0.0 0.35 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TMF_DNA_bd PF12329.8 KND86817.1 - 0.04 13.9 0.5 0.04 13.9 0.5 7.2 3 1 5 8 8 7 0 TATA element modulatory factor 1 DNA binding DUF3371 PF11851.8 KND86817.1 - 0.075 14.1 1.7 0.31 12.1 0.0 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF3371) Myosin_tail_1 PF01576.19 KND86817.1 - 0.15 9.8 60.7 0.0032 15.4 25.2 2.7 1 1 1 2 2 2 0 Myosin tail CARD PF00619.21 KND86817.1 - 0.22 11.6 3.9 0.25 11.4 0.0 2.9 3 0 0 3 3 3 0 Caspase recruitment domain Baculo_PEP_C PF04513.12 KND86817.1 - 0.27 11.3 9.0 1.8 8.6 0.9 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 KND86817.1 - 0.72 10.3 22.7 0.18 12.2 0.6 6.5 5 1 1 6 6 6 0 Lipoprotein leucine-zipper TraF_2 PF13729.6 KND86817.1 - 0.79 9.0 6.7 18 4.5 0.0 3.6 3 1 1 4 4 4 0 F plasmid transfer operon, TraF, protein Bacillus_HBL PF05791.11 KND86817.1 - 0.81 9.5 25.4 1.2 8.9 8.2 4.5 3 2 2 5 5 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 KND86817.1 - 2.3 8.3 34.6 0.018 15.1 4.8 5.8 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 KND86817.1 - 2.4 8.7 35.7 27 5.3 2.4 5.4 2 1 2 4 4 3 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 KND86817.1 - 3 8.4 19.9 13 6.3 0.4 6.1 2 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein UPF0449 PF15136.6 KND86817.1 - 3.2 8.3 26.9 13 6.4 7.0 5.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 FPP PF05911.11 KND86817.1 - 4.2 5.4 46.8 0.13 10.4 6.9 3.8 2 1 2 4 4 4 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 KND86817.1 - 4.4 7.8 67.5 2.1 8.9 20.3 5.4 3 2 1 4 4 4 0 Apg6 coiled-coil region RPW8 PF05659.11 KND86817.1 - 5.3 6.7 16.0 7.2 6.3 1.0 3.4 2 2 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Filament PF00038.21 KND86817.1 - 6.4 6.3 55.5 0.18 11.4 42.2 3.9 3 1 0 3 3 3 0 Intermediate filament protein ParE_toxin PF05016.15 KND86817.1 - 7.1 7.3 8.5 4.6 7.9 0.9 3.8 3 1 1 4 4 3 0 ParE toxin of type II toxin-antitoxin system, parDE Lebercilin PF15619.6 KND86817.1 - 8.3 6.0 56.0 1.7 8.3 10.4 4.2 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Vma12 PF11712.8 KND86818.1 - 8.4e-43 145.8 0.0 1.2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PepSY_TM PF03929.16 KND86818.1 - 0.04 13.6 0.2 0.086 12.5 0.0 1.5 1 1 0 1 1 1 0 PepSY-associated TM region polyprenyl_synt PF00348.17 KND86819.1 - 4.2e-75 252.1 0.0 6.5e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KND86819.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Sugar_tr PF00083.24 KND86820.1 - 3.5e-63 214.0 12.2 3.5e-63 214.0 12.2 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86820.1 - 3.7e-06 26.1 22.4 7.6e-05 21.8 18.9 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily zf-C2H2_3 PF13878.6 KND86821.1 - 5.3e-08 32.6 0.0 9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO NapD PF03927.13 KND86822.1 - 0.063 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 NapD protein Cnn_1N PF07989.11 KND86823.1 - 3.6e-22 78.3 11.2 3.6e-22 78.3 11.2 12.1 9 2 2 11 11 11 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 KND86823.1 - 1.8e-09 37.7 11.3 1.8e-09 37.7 11.3 12.5 12 1 0 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Spectrin PF00435.21 KND86823.1 - 0.0089 16.5 0.1 0.0089 16.5 0.1 8.5 4 1 1 6 6 6 1 Spectrin repeat NPV_P10 PF05531.12 KND86823.1 - 0.061 13.8 21.2 0.42 11.1 0.1 6.0 6 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF1479 PF07350.12 KND86824.1 - 6.9e-161 535.6 0.0 8e-161 535.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KND86824.1 - 0.00062 20.1 0.2 0.92 9.7 0.1 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1993 PF09351.10 KND86825.1 - 6.4e-50 169.4 0.0 7.2e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Mrx7 PF10906.8 KND86826.1 - 1.4e-08 34.8 0.0 1.8e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 DeoC PF01791.9 KND86828.1 - 5.6e-05 22.9 0.3 7.8e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase ETC_C1_NDUFA5 PF04716.14 KND86829.1 - 4.4e-25 87.3 1.7 3.3e-23 81.3 0.0 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region SAWADEE PF16719.5 KND86829.1 - 0.079 13.0 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 SAWADEE domain BAR_2 PF10455.9 KND86830.1 - 6.9e-56 189.5 0.5 1e-55 189.0 0.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KND86830.1 - 3e-20 72.9 4.9 2e-18 66.9 4.9 2.1 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KND86830.1 - 0.0038 17.0 1.1 0.0075 16.0 0.3 2.0 2 1 0 2 2 2 1 BAR domain of APPL family GCP_C_terminal PF04130.13 KND86830.1 - 0.05 13.1 0.1 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal STG PF15809.5 KND86830.1 - 0.093 12.8 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family APH PF01636.23 KND86831.1 - 5.6e-11 42.8 0.0 1.1e-10 41.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86831.1 - 5.1e-07 29.5 0.1 7.3e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KND86831.1 - 0.066 12.5 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PIP5K PF01504.18 KND86831.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RIO1 PF01163.22 KND86831.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family NAT PF04768.13 KND86832.1 - 2.8e-52 176.8 0.0 2.9e-51 173.5 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase IQ PF00612.27 KND86833.1 - 0.088 12.6 0.4 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fungal_trans PF04082.18 KND86835.1 - 1.6e-38 132.3 0.0 5.4e-38 130.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86835.1 - 6.9e-08 32.5 8.3 1.2e-07 31.7 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.14 KND86836.1 - 2.2e-162 541.1 30.2 2.8e-162 540.7 30.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KND86836.1 - 9.4e-10 38.6 2.1 6.5e-09 35.8 2.1 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND86836.1 - 5.3e-09 35.9 0.4 1.3e-08 34.7 0.1 1.7 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KND86836.1 - 1.5e-05 24.5 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 KND86836.1 - 0.0059 15.6 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase DUF3687 PF12459.8 KND86836.1 - 0.15 11.6 1.4 0.71 9.4 1.4 2.2 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein NAD_binding_2 PF03446.15 KND86837.1 - 1.4e-28 100.1 0.0 2.6e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ATP_synt_H PF05493.13 KND86837.1 - 1.1e-15 57.9 7.1 1.1e-15 57.9 7.1 2.9 2 1 0 2 2 2 1 ATP synthase subunit H NAD_binding_11 PF14833.6 KND86837.1 - 2.6e-09 37.4 0.3 4.8e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 KND86837.1 - 3.8e-09 36.7 0.0 7.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KND86837.1 - 4.4e-09 36.8 0.1 1.8e-08 34.8 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 KND86837.1 - 0.0022 18.2 0.1 0.0066 16.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KND86837.1 - 0.05 13.5 0.3 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding KR PF08659.10 KND86837.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 KR domain OCD_Mu_crystall PF02423.15 KND86837.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Arv1 PF04161.13 KND86838.1 - 2.4e-69 233.7 0.0 4.1e-69 232.9 0.0 1.4 1 1 0 1 1 1 1 Arv1-like family LysM PF01476.20 KND86838.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 LysM domain Abhydrolase_3 PF07859.13 KND86839.1 - 1.1e-46 159.3 0.2 1.5e-46 158.9 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KND86839.1 - 9.5e-06 24.8 0.0 2.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 KND86839.1 - 0.22 11.3 0.1 16 5.2 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Fungal_trans_2 PF11951.8 KND86840.1 - 2e-59 201.3 0.2 2.5e-59 201.0 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86840.1 - 0.00011 22.3 15.5 0.00018 21.5 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3717 PF12512.8 KND86840.1 - 0.2 11.5 1.1 5.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) DUF2946 PF11162.8 KND86840.1 - 2.6 8.8 14.8 0.51 11.0 10.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Collagen PF01391.18 KND86840.1 - 4.1 7.3 6.0 6.8 6.5 6.0 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAD_binding_3 PF01494.19 KND86841.1 - 7.1e-18 65.0 0.0 1.6e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND86841.1 - 8.5e-08 32.3 1.3 2.5e-07 30.8 1.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND86841.1 - 1.4e-06 27.7 0.2 2.1e-06 27.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KND86841.1 - 2.3e-05 24.0 1.2 3.7e-05 23.3 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND86841.1 - 2.4e-05 23.7 0.6 3.3e-05 23.3 0.6 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND86841.1 - 0.00037 20.2 3.4 0.00051 19.7 3.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND86841.1 - 0.0032 18.0 0.3 0.0078 16.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KND86841.1 - 0.0037 16.4 0.3 0.0055 15.8 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 KND86841.1 - 0.0055 16.0 0.5 0.01 15.2 0.5 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KND86841.1 - 0.023 13.6 0.0 0.071 12.0 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 KND86841.1 - 0.033 12.9 0.4 0.046 12.4 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KND86841.1 - 0.052 12.6 0.1 0.077 12.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KND86841.1 - 0.057 12.7 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KND86841.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 KND86843.1 - 1.1e-20 74.1 0.0 2.2e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KND86843.1 - 5.5e-11 42.1 0.0 1.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KND86843.1 - 1.9e-10 40.7 0.1 3.5e-10 39.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND86843.1 - 4.4e-10 39.0 0.0 1.3e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KND86843.1 - 1.8e-07 31.2 0.1 3.4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KND86843.1 - 8.4e-05 22.1 0.1 0.0024 17.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 KND86843.1 - 0.00027 20.1 0.0 0.00045 19.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KND86843.1 - 0.0015 18.2 0.0 0.023 14.3 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KND86843.1 - 0.021 14.0 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 KND86844.1 - 1.2e-17 63.9 1.0 1.6e-17 63.4 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86844.1 - 0.00046 20.3 11.4 0.00077 19.5 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KND86845.1 - 1.6e-77 261.3 18.8 1.8e-77 261.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND86845.1 - 6.2e-22 78.0 31.8 2.1e-20 73.0 22.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 KND86845.1 - 0.0011 17.6 0.7 0.0011 17.6 0.7 1.7 2 0 0 2 2 2 1 Ferroportin1 (FPN1) AnmK PF03702.14 KND86846.1 - 1.2e-86 291.1 0.0 1.4e-86 290.9 0.0 1.1 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase DUF3140 PF11338.8 KND86847.1 - 7.5e-19 68.0 1.9 7.5e-19 68.0 1.9 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 KND86847.1 - 8.3e-14 51.5 2.9 8.3e-14 51.5 2.9 2.4 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain UPF0688 PF15772.5 KND86847.1 - 0.057 13.7 9.2 0.1 12.8 9.2 1.4 1 0 0 1 1 1 0 UPF0688 family AMP-binding PF00501.28 KND86848.1 - 4.7e-126 420.8 0.1 3.2e-79 266.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KND86848.1 - 1.2e-98 330.8 0.0 2.4e-48 165.0 0.0 2.3 2 0 0 2 2 2 2 Condensation domain MFS_1 PF07690.16 KND86848.1 - 2.1e-32 112.4 33.8 2.4e-32 112.3 32.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PP-binding PF00550.25 KND86848.1 - 4.7e-27 94.1 2.4 5.4e-13 49.1 0.2 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site MFS_4 PF06779.14 KND86848.1 - 0.00022 20.7 6.7 0.00022 20.7 6.7 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Csm1 PF12539.8 KND86849.1 - 1.5e-33 115.2 0.0 2.6e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Rootletin PF15035.6 KND86849.1 - 4.8e-05 23.5 9.5 8.3e-05 22.7 9.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion PspA_IM30 PF04012.12 KND86849.1 - 0.00096 18.8 12.3 0.00096 18.8 12.3 1.6 2 0 0 2 2 2 1 PspA/IM30 family EzrA PF06160.12 KND86849.1 - 0.0075 14.5 3.1 0.012 13.9 3.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.6 KND86849.1 - 0.04 13.3 10.3 0.13 11.5 2.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 KND86849.1 - 0.045 11.7 1.1 0.062 11.3 1.1 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 KND86849.1 - 0.063 13.4 7.3 0.095 12.8 7.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 KND86849.1 - 0.084 11.9 7.0 0.14 11.2 7.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KND86849.1 - 0.086 11.7 9.4 0.14 11.0 9.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 KND86849.1 - 0.25 10.6 11.9 0.35 10.1 5.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 KND86849.1 - 0.27 11.2 10.7 0.33 11.0 9.0 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KND86849.1 - 0.43 10.6 13.6 1.5 8.9 13.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 KND86849.1 - 0.47 10.5 12.2 0.38 10.8 9.9 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 KND86849.1 - 0.51 10.6 4.8 1.4 9.1 0.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Fmp27_WPPW PF10359.9 KND86849.1 - 0.56 9.0 3.7 0.85 8.4 3.7 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DHR10 PF18595.1 KND86849.1 - 0.93 9.6 17.9 1.7 8.7 6.8 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 KND86849.1 - 1.1 9.9 12.6 1.4 9.5 10.5 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 KND86849.1 - 1.6 9.0 8.7 2.7 8.3 7.7 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AT_hook PF02178.19 KND86849.1 - 2.2 8.4 7.7 10 6.4 3.5 2.8 2 0 0 2 2 2 0 AT hook motif YabA PF06156.13 KND86849.1 - 4.1 8.1 7.4 8.5 7.1 4.0 2.7 1 1 2 3 3 3 0 Initiation control protein YabA DUF2203 PF09969.9 KND86849.1 - 8 7.2 7.8 2.7 8.8 2.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 KND86849.1 - 8.7 4.7 8.1 15 4.0 8.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.29 KND86850.1 - 6.4e-37 126.9 0.0 1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND86850.1 - 1.6e-08 34.2 0.1 3.3e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KND86850.1 - 8.9e-06 26.0 0.6 0.0041 17.4 0.0 3.5 2 1 2 4 4 4 1 AAA domain AAA_14 PF13173.6 KND86850.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KND86850.1 - 1.7e-05 24.6 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KND86850.1 - 4.2e-05 23.6 0.1 0.00038 20.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND86850.1 - 7.2e-05 23.2 0.1 0.003 17.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 KND86850.1 - 8.6e-05 22.7 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 KND86850.1 - 0.00063 19.2 0.1 1.3 8.4 0.0 2.9 2 1 0 3 3 3 2 Bacterial TniB protein Sigma54_activat PF00158.26 KND86850.1 - 0.0013 18.4 0.0 0.049 13.3 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KND86850.1 - 0.0015 18.3 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KND86850.1 - 0.0018 17.7 0.1 0.0045 16.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KND86850.1 - 0.0022 18.2 0.3 0.0056 16.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 KND86850.1 - 0.0034 17.0 1.6 0.13 11.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KND86850.1 - 0.0071 16.9 1.1 0.037 14.6 0.0 2.4 2 1 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 KND86850.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 KND86850.1 - 0.027 14.7 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 KND86850.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 KND86850.1 - 0.03 14.2 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KND86850.1 - 0.032 14.1 0.0 0.093 12.6 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KND86850.1 - 0.035 14.6 0.0 0.12 12.8 0.0 2.1 2 1 0 2 2 1 0 ABC transporter DUF815 PF05673.13 KND86850.1 - 0.036 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KND86850.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KND86850.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KND86850.1 - 0.071 12.3 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.13 KND86850.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KND86850.1 - 0.12 12.2 0.0 0.79 9.6 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Oxidored_nitro PF00148.19 KND86850.1 - 0.15 10.8 0.0 0.66 8.6 0.0 1.8 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase AAA_24 PF13479.6 KND86850.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 KND86850.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KND86850.1 - 0.51 10.8 0.0 0.51 10.8 0.0 2.4 3 0 0 3 3 1 0 AAA domain BLACT_WH PF17778.1 KND86850.1 - 0.59 10.2 2.2 1.7 8.7 0.3 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain SWIRM PF04433.17 KND86851.1 - 8.9e-32 109.3 0.1 1.7e-31 108.4 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KND86851.1 - 2.4e-30 104.3 4.3 5e-30 103.3 4.3 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KND86851.1 - 1.9e-09 37.6 0.1 4.7e-09 36.3 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND86851.1 - 9.3e-05 22.6 0.1 0.00019 21.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KND86851.1 - 0.0063 16.3 4.5 0.013 15.3 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SANT_DAMP1_like PF16282.5 KND86851.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Fungal_trans PF04082.18 KND86853.1 - 1e-09 37.8 0.0 2.2e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 KND86853.1 - 3.3e-07 30.4 2.1 5.8e-07 29.7 0.7 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND86853.1 - 1.4e-05 24.9 6.6 2.5e-05 24.0 4.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Zn_clus PF00172.18 KND86853.1 - 2.4e-05 24.4 7.2 4.8e-05 23.4 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KND86853.1 - 2.4e-05 23.7 0.6 8.8e-05 21.9 0.4 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND86853.1 - 0.00012 21.5 1.8 0.3 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KND86853.1 - 0.00043 19.5 0.0 0.00072 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KND86853.1 - 0.001 18.2 0.3 0.001 18.2 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KND86853.1 - 0.003 17.0 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND86853.1 - 0.0037 17.8 2.2 0.0074 16.8 1.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KND86853.1 - 0.0057 16.0 0.1 0.05 12.9 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KND86853.1 - 0.012 14.7 1.0 0.026 13.6 1.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 KND86853.1 - 0.066 13.1 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 Rossmann-like domain HI0933_like PF03486.14 KND86853.1 - 0.11 11.2 1.1 0.21 10.2 1.1 1.5 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KND86853.1 - 0.2 11.6 1.0 0.43 10.4 1.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KND86853.1 - 0.52 9.5 2.0 1.7 7.8 0.8 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cyclase PF04199.13 KND86854.1 - 6.8e-15 55.5 0.0 9.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase CoA_transf_3 PF02515.17 KND86855.1 - 2.2e-44 152.1 0.4 2.6e-41 142.0 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Metal_resist PF13801.6 KND86855.1 - 0.097 12.9 1.0 0.26 11.5 0.3 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Dioxygenase_C PF00775.21 KND86856.1 - 6e-44 149.6 0.0 7.9e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KND86856.1 - 1e-28 98.9 0.3 2.2e-28 97.9 0.1 1.6 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KND86856.1 - 5.3e-05 23.4 0.2 0.00023 21.4 0.2 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KND86856.1 - 0.022 15.1 0.0 0.55 10.6 0.0 2.4 2 0 0 2 2 2 0 Prealbumin-like fold domain Lipase_C PF18067.1 KND86856.1 - 0.032 14.8 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipase C-terminal domain CarbopepD_reg_2 PF13715.6 KND86856.1 - 0.16 12.0 0.1 4.1 7.5 0.1 2.7 3 0 0 3 3 3 0 CarboxypepD_reg-like domain DUF4440 PF14534.6 KND86857.1 - 0.044 14.2 0.1 0.057 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Abhydrolase_6 PF12697.7 KND86858.1 - 1.5e-20 74.8 0.1 1.9e-20 74.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND86858.1 - 7.1e-18 64.7 0.0 8.8e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND86858.1 - 2.7e-16 60.0 0.1 1.9e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1057 PF06342.12 KND86858.1 - 0.00013 21.1 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.13 KND86858.1 - 0.00015 20.4 0.1 0.028 13.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.16 KND86858.1 - 0.00019 21.3 0.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KND86858.1 - 0.00028 19.9 0.3 0.001 18.1 0.3 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 KND86858.1 - 0.0005 20.0 0.1 0.045 13.6 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 KND86858.1 - 0.00061 19.6 1.2 0.0086 15.8 0.3 2.2 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.21 KND86858.1 - 0.0011 18.5 0.0 0.65 9.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KND86858.1 - 0.0015 18.1 0.0 0.44 10.0 0.0 3.3 2 2 1 3 3 3 1 Dienelactone hydrolase family Thioesterase PF00975.20 KND86858.1 - 0.0029 17.8 0.0 0.0043 17.2 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KND86858.1 - 0.0049 16.7 0.1 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KND86858.1 - 0.017 14.1 0.3 0.049 12.7 0.3 1.6 1 1 0 1 1 1 0 Chlorophyllase Esterase_phd PF10503.9 KND86858.1 - 0.018 14.6 0.3 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 KND86858.1 - 0.048 13.5 0.1 0.072 12.9 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KND86858.1 - 0.12 12.2 1.6 0.2 11.5 0.5 1.8 1 1 1 2 2 2 0 Lipase (class 3) Yip1 PF04893.17 KND86859.1 - 1e-11 44.9 13.6 1.7e-11 44.2 13.6 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KND86859.1 - 0.053 13.3 6.6 0.091 12.5 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Amidohydro_2 PF04909.14 KND86860.1 - 8.1e-35 121.0 1.0 1e-34 120.7 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase RNA_pol_I_TF PF04090.12 KND86861.1 - 0.013 15.0 0.0 0.099 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor EPSP_synthase PF00275.20 KND86861.1 - 0.057 12.1 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) TPR_6 PF13174.6 KND86861.1 - 0.32 11.7 6.0 28 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 KND86862.1 - 1.7e-12 47.6 18.7 3.3e-05 24.6 0.5 6.4 7 1 0 7 7 7 5 WD domain, G-beta repeat ABC2_membrane PF01061.24 KND86863.1 - 8.6e-51 172.3 27.6 4.2e-27 94.9 7.3 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KND86863.1 - 1.5e-47 161.5 0.0 8.6e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KND86863.1 - 3.1e-12 46.9 10.8 0.016 15.1 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND86863.1 - 3.9e-09 36.3 0.4 0.00093 18.7 0.1 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND86863.1 - 1.3e-07 32.0 0.0 0.022 15.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KND86863.1 - 1.7e-07 30.9 2.1 0.0027 17.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND86863.1 - 2.6e-07 30.7 1.1 0.011 15.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KND86863.1 - 3.4e-07 30.8 0.2 0.0076 16.7 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KND86863.1 - 6.1e-07 30.1 1.7 0.0087 16.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KND86863.1 - 1.9e-06 27.8 0.1 0.0053 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KND86863.1 - 1.9e-06 27.9 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 KND86863.1 - 4.3e-06 27.1 0.1 0.015 15.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KND86863.1 - 5.4e-05 23.6 0.7 0.027 14.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 KND86863.1 - 0.00015 21.7 0.1 0.66 9.8 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KND86863.1 - 0.00044 20.6 0.2 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 KND86863.1 - 0.00062 19.4 0.4 0.88 9.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KND86863.1 - 0.00072 19.7 0.1 0.35 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KND86863.1 - 0.00075 19.3 0.6 5.1 6.7 0.1 3.2 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 KND86863.1 - 0.00087 18.4 1.0 0.18 10.9 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein PDR_CDR PF06422.12 KND86863.1 - 0.0013 18.6 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter cobW PF02492.19 KND86863.1 - 0.0019 17.8 3.2 0.56 9.8 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KND86863.1 - 0.002 18.2 2.4 0.095 12.8 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KND86863.1 - 0.0025 17.6 1.3 0.96 9.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND86863.1 - 0.0052 16.8 0.7 6.3 6.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 KND86863.1 - 0.0054 16.1 1.7 0.31 10.3 0.2 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 KND86863.1 - 0.0062 16.4 0.6 0.67 9.7 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KND86863.1 - 0.011 15.7 1.5 0.37 10.7 0.1 3.4 4 0 0 4 4 4 0 NTPase SbcCD_C PF13558.6 KND86863.1 - 0.018 15.3 2.2 6.3 7.1 0.2 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DnaB_C PF03796.15 KND86863.1 - 0.02 14.2 0.2 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Pox_A32 PF04665.12 KND86863.1 - 0.021 14.3 0.8 0.88 9.0 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 KND86863.1 - 0.022 14.6 0.8 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.9 KND86863.1 - 0.023 13.5 0.5 1 8.1 0.2 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Roc PF08477.13 KND86863.1 - 0.032 14.5 0.5 4.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 KND86863.1 - 0.032 14.0 0.5 0.88 9.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KND86863.1 - 0.046 14.3 0.1 17 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KND86863.1 - 0.098 12.1 0.3 15 4.9 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Septin PF00735.18 KND86863.1 - 0.11 11.7 0.5 1.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Septin AAA_11 PF13086.6 KND86863.1 - 0.12 12.2 0.1 16 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KND86863.1 - 0.12 11.6 0.5 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 KND86863.1 - 0.13 11.8 1.2 5.8 6.5 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 KND86863.1 - 0.15 11.5 0.7 18 4.7 0.2 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KND86863.1 - 0.19 12.2 0.8 31 5.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 KND86863.1 - 0.23 11.2 0.9 24 4.6 0.1 2.7 3 0 0 3 3 2 0 Cytidylate kinase TsaE PF02367.17 KND86863.1 - 0.26 11.3 0.6 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 KND86863.1 - 0.28 10.3 0.1 3 6.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF3087 PF11286.8 KND86863.1 - 1.3 8.5 2.8 0.8 9.2 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3087) ABC2_membrane_3 PF12698.7 KND86863.1 - 3.1 6.8 26.0 1.6 7.7 7.0 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein GATase PF00117.28 KND86864.1 - 6.2e-37 127.2 0.0 1.5e-36 126.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KND86864.1 - 1.1e-34 118.3 0.2 2.3e-34 117.3 0.2 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KND86864.1 - 2.2e-10 40.1 0.1 2.9e-07 29.9 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KND86864.1 - 2.8e-07 30.5 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 KND86864.1 - 0.0002 20.3 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 KND86864.1 - 0.0022 17.6 0.1 0.0039 16.8 0.1 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 KND86864.1 - 0.0064 16.0 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KND86864.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 KND86864.1 - 0.036 13.3 0.1 0.055 12.8 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 KND86864.1 - 0.037 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 PP-loop family MCM PF00493.23 KND86866.1 - 7.2e-98 326.1 0.1 1.2e-97 325.4 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KND86866.1 - 3.9e-31 107.5 0.1 7.2e-31 106.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND86866.1 - 5.3e-24 84.5 1.9 1.1e-23 83.5 1.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND86866.1 - 3.4e-12 46.9 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND86866.1 - 3.5e-07 29.8 0.0 4.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KND86866.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND86866.1 - 0.0097 15.6 0.0 0.035 13.8 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain IceA2 PF05862.11 KND86866.1 - 0.075 13.0 0.0 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein AAA_5 PF07728.14 KND86866.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PfkB PF00294.24 KND86867.1 - 1e-14 54.6 0.0 3.8e-09 36.3 0.4 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF3085 PF11284.8 KND86867.1 - 0.04 14.2 0.2 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3085) SRP72 PF08492.12 KND86867.1 - 0.44 11.0 2.4 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 SRP72 RNA-binding domain CAP_N PF01213.19 KND86868.1 - 1.3e-109 366.6 0.0 1.3e-109 366.6 0.0 1.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KND86868.1 - 1e-54 184.4 0.8 1.4e-54 184.0 0.8 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Carn_acyltransf PF00755.20 KND86869.1 - 1.2e-198 661.5 0.0 1.4e-198 661.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Aminotran_5 PF00266.19 KND86870.1 - 1.1e-30 106.8 0.0 2.7e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF3435 PF11917.8 KND86871.1 - 0.0045 16.0 0.2 0.42 9.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3435) 2_5_RNA_ligase2 PF13563.6 KND86873.1 - 8.6e-31 106.9 3.0 1.3e-30 106.3 1.9 1.9 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 KND86873.1 - 5.6e-19 68.7 0.2 1.5e-18 67.3 0.2 1.8 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 KND86873.1 - 1.1e-11 44.2 0.0 1.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 KND86873.1 - 3e-08 33.5 0.4 8.8e-08 31.9 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 KND86873.1 - 0.042 14.1 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Exo_endo_phos_2 PF14529.6 KND86873.1 - 0.19 11.6 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MutL_C PF08676.11 KND86874.1 - 1.8e-22 79.7 0.0 3.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KND86874.1 - 2.2e-18 66.0 0.0 6.3e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KND86874.1 - 2.5e-11 43.6 0.0 5.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KND86874.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.14 KND86876.1 - 3.2e-10 39.7 0.1 6.3e-09 35.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND86876.1 - 0.026 14.8 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ETF PF01012.21 KND86877.1 - 7.4e-45 153.1 1.5 1.2e-44 152.4 1.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KND86877.1 - 3.4e-34 116.7 0.5 3.4e-34 116.7 0.5 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Cys_Met_Meta_PP PF01053.20 KND86878.1 - 2.9e-137 457.3 0.0 3.4e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KND86878.1 - 4.8e-06 26.0 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND86878.1 - 1.1e-05 24.6 0.0 2.5e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KND86878.1 - 0.00036 20.0 0.0 0.00094 18.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KND86878.1 - 0.00044 18.9 0.0 0.0011 17.6 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 KND86878.1 - 0.00075 18.4 0.0 0.0014 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KND86878.1 - 0.013 14.8 0.2 0.034 13.4 0.2 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 KND86878.1 - 0.14 12.0 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus Serinc PF03348.15 KND86879.1 - 8.5e-152 506.0 5.9 9.9e-152 505.8 5.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 KND86880.1 - 2.4e-18 66.2 35.6 1.3e-12 47.3 21.7 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KND86880.1 - 3.4e-16 59.5 1.7 3.4e-16 59.5 1.7 2.2 2 0 0 2 2 2 1 Nodulin-like MFS_3 PF05977.13 KND86880.1 - 0.11 10.8 4.2 0.087 11.2 0.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector PGAP1 PF07819.13 KND86881.1 - 4.7e-93 311.2 0.8 8.7e-93 310.3 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND86881.1 - 2.8e-05 24.8 0.6 8.6e-05 23.2 0.6 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4834 PF16118.5 KND86881.1 - 0.00077 20.4 3.7 0.0047 17.9 0.1 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) DUF3464 PF11947.8 KND86881.1 - 0.0017 18.2 2.1 0.0031 17.3 0.2 2.3 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 MctB PF11382.8 KND86881.1 - 0.012 15.4 1.4 0.012 15.4 1.4 1.8 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF2722 PF10846.8 KND86881.1 - 0.017 14.1 15.3 0.033 13.1 15.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) LapA_dom PF06305.11 KND86881.1 - 0.018 14.9 3.5 0.98 9.3 0.0 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Hydrolase_4 PF12146.8 KND86881.1 - 0.023 14.0 0.0 0.065 12.5 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TERB2 PF15101.6 KND86881.1 - 0.095 12.7 3.0 0.17 11.9 3.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Chlorophyllase2 PF12740.7 KND86881.1 - 0.11 11.3 0.0 0.38 9.6 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF676 PF05057.14 KND86881.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Suf PF05843.14 KND86881.1 - 0.19 11.7 4.4 0.37 10.7 4.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 KND86881.1 - 0.3 11.7 14.7 0.082 13.6 7.7 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 KND86881.1 - 2 8.2 7.7 4.2 7.2 7.7 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4199 PF13858.6 KND86881.1 - 5.8 7.3 7.1 5 7.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Hydin_ADK PF17213.3 KND86881.1 - 6.9 6.9 8.9 0.17 12.2 1.5 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 KND86881.1 - 9.5 5.8 25.1 18 4.8 25.1 1.3 1 0 0 1 1 1 0 Spt20 family CFEM PF05730.11 KND86882.1 - 5.1e-07 29.7 7.4 8.2e-07 29.0 7.4 1.3 1 0 0 1 1 1 1 CFEM domain ketoacyl-synt PF00109.26 KND86883.1 - 2.3e-66 224.0 0.0 4.5e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KND86883.1 - 7.9e-65 219.0 2.4 1.3e-64 218.3 2.4 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KND86883.1 - 9.2e-54 183.1 0.0 1.4e-53 182.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KND86883.1 - 1.2e-44 152.4 1.4 4.2e-25 88.7 0.6 2.6 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 KND86883.1 - 3.6e-34 117.3 0.1 9.8e-34 115.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KND86883.1 - 2.4e-21 76.3 0.0 5.9e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KND86883.1 - 2.4e-18 66.7 0.0 3.2e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KND86883.1 - 5.3e-15 56.6 0.0 1.9e-14 54.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND86883.1 - 1.9e-14 53.7 0.0 5.2e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KND86883.1 - 3.1e-11 43.8 0.0 7.5e-10 39.4 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KND86883.1 - 2e-08 34.5 0.0 2.2e-07 31.1 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 KND86883.1 - 3.7e-08 33.9 0.0 3.3e-07 30.9 0.0 2.8 4 0 0 4 4 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND86883.1 - 2.6e-07 30.6 0.0 8.5e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86883.1 - 4.3e-07 29.8 0.0 1.5e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KND86883.1 - 6.7e-06 25.9 0.5 0.21 11.3 0.0 3.1 3 1 0 3 3 3 2 Lysine methyltransferase ADH_N PF08240.12 KND86883.1 - 4.6e-05 23.3 0.1 0.00012 21.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KND86883.1 - 0.00066 19.1 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 KND86883.1 - 0.097 12.1 0.3 1.8 8.0 0.2 2.7 2 1 0 2 2 2 0 short chain dehydrogenase AMP-binding PF00501.28 KND86884.1 - 1.3e-66 225.0 0.0 1.6e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND86884.1 - 2.7e-14 53.9 0.0 6.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-C2H2_2 PF12756.7 KND86885.1 - 3.7e-23 81.8 4.7 3.1e-22 78.8 1.7 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KND86885.1 - 0.0009 19.9 6.6 0.92 10.5 0.0 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND86885.1 - 0.014 15.7 0.3 0.51 10.7 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND86885.1 - 0.06 13.7 1.0 0.28 11.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KND86885.1 - 5.5 7.6 7.8 4.8 7.8 0.1 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3328 PF11807.8 KND86886.1 - 5.5e-33 114.6 0.6 8.6e-32 110.7 0.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) CDH-cyt PF16010.5 KND86887.1 - 1.3e-11 44.5 0.6 2.7e-11 43.5 0.7 1.4 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KND86887.1 - 0.0032 17.2 1.7 0.0081 15.9 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DoxD PF04173.13 KND86887.1 - 0.049 13.5 0.6 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 TQO small subunit DoxD ATP1G1_PLM_MAT8 PF02038.16 KND86887.1 - 0.084 12.3 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4079 PF13301.6 KND86887.1 - 1.6 8.9 9.8 4.2 7.5 9.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) SdpI PF13630.6 KND86887.1 - 7.6 6.7 11.2 0.89 9.7 2.4 2.8 2 0 0 2 2 2 0 SdpI/YhfL protein family DIOX_N PF14226.6 KND86888.1 - 1.4e-23 83.9 0.0 2e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND86888.1 - 4.9e-10 39.8 0.0 8.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GP120 PF00516.18 KND86888.1 - 0.23 10.0 0.0 0.32 9.5 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 OPT PF03169.15 KND86889.1 - 2.4e-06 26.5 0.1 2.7e-06 26.4 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CFEM PF05730.11 KND86890.1 - 2.2e-10 40.5 7.7 3.8e-10 39.7 7.7 1.4 1 0 0 1 1 1 1 CFEM domain Spc7_N PF15402.6 KND86890.1 - 0.14 10.4 2.8 0.19 10.0 2.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF1180 PF06679.12 KND86890.1 - 4.2 7.8 6.5 6.1 7.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 KND86891.1 - 1.4e-09 37.4 64.6 1.5e-07 30.7 41.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KND86891.1 - 6.8e-05 21.5 24.1 0.0001 20.9 24.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BC10 PF06726.12 KND86891.1 - 0.06 13.6 1.2 15 5.9 0.2 3.0 2 0 0 2 2 2 0 Bladder cancer-related protein BC10 Pyr_redox_2 PF07992.14 KND86892.1 - 2.7e-39 135.2 0.2 3.4e-39 134.8 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND86892.1 - 5.6e-11 42.8 0.4 7.6e-09 36.0 1.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND86892.1 - 3.7e-08 33.3 1.4 0.0088 15.7 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KND86892.1 - 6.9e-06 25.2 0.4 0.11 11.3 0.3 3.0 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 KND86892.1 - 9.3e-06 25.7 1.0 2.7 8.0 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KND86892.1 - 0.0002 20.8 0.1 0.00032 20.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND86892.1 - 0.0024 17.1 0.1 0.011 14.9 0.1 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KND86892.1 - 0.012 14.7 1.6 2.9 6.8 0.7 3.1 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 KND86892.1 - 0.017 14.4 1.1 0.15 11.3 0.5 2.2 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KND86892.1 - 0.045 12.8 0.3 1.9 7.5 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 KND86892.1 - 0.073 13.3 0.1 4.8 7.5 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KND86892.1 - 0.095 12.0 1.1 0.13 11.6 0.4 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 KND86892.1 - 0.11 12.7 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 KND86892.1 - 0.12 11.0 1.8 1.1 7.9 0.2 2.8 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 KND86892.1 - 5.7 5.9 7.5 9.9 5.1 3.9 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A ketoacyl-synt PF00109.26 KND86893.1 - 1.1e-63 215.2 0.0 2.4e-63 214.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KND86893.1 - 9.2e-62 209.0 0.0 1.4e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KND86893.1 - 5.5e-61 205.6 0.3 1.1e-60 204.6 0.3 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KND86893.1 - 7.9e-46 157.0 0.0 4e-44 151.4 0.0 2.4 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND86893.1 - 1.2e-33 115.6 0.4 4.9e-33 113.6 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KND86893.1 - 8.8e-20 72.1 0.0 4.9e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KND86893.1 - 2.1e-17 63.7 0.0 5.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KND86893.1 - 4.1e-17 62.7 0.1 1.3e-14 54.5 0.1 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KND86893.1 - 5.8e-14 52.2 0.0 3.9e-13 49.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KND86893.1 - 2.1e-09 37.4 0.0 1e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86893.1 - 4.8e-09 36.8 0.0 2.4e-08 34.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 KND86893.1 - 1.1e-08 34.8 0.2 2e-07 30.7 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 KND86893.1 - 6.7e-08 32.8 0.1 1.8e-07 31.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KND86893.1 - 1.8e-07 31.0 0.3 2.2e-06 27.5 0.3 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 KND86893.1 - 4.1e-07 30.6 0.0 1.3e-06 29.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86893.1 - 1.8e-05 24.5 0.0 4.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KND86893.1 - 0.00033 20.4 0.0 0.025 14.3 0.0 3.1 3 0 0 3 3 3 1 Lysine methyltransferase Ubie_methyltran PF01209.18 KND86893.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KND86893.1 - 0.073 12.7 0.0 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase bZIP_1 PF00170.21 KND86894.1 - 3.4e-05 23.8 6.1 8.5e-05 22.6 6.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND86894.1 - 0.0054 16.8 12.4 0.0089 16.1 11.4 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 KND86894.1 - 0.11 13.0 7.8 0.27 11.8 7.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.9 KND86894.1 - 0.66 8.5 10.6 0.96 7.9 10.6 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 KND86894.1 - 5.1 5.8 6.8 9.7 4.8 6.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein p450 PF00067.22 KND86895.1 - 1.9e-58 198.3 0.0 2.4e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 4HBT_2 PF13279.6 KND86896.1 - 3.3e-06 27.6 0.0 4.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily ABC_tran PF00005.27 KND86897.1 - 2.5e-38 131.7 0.0 1e-18 68.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND86897.1 - 5.2e-27 95.2 36.0 4.6e-20 72.4 15.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KND86897.1 - 9.1e-08 31.8 0.1 0.022 14.2 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KND86897.1 - 0.0018 18.7 0.1 0.029 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KND86897.1 - 0.0056 16.5 0.5 0.094 12.5 0.1 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KND86897.1 - 0.009 16.3 0.1 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND86897.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KND86897.1 - 0.013 16.0 0.0 0.025 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KND86897.1 - 0.016 15.5 2.4 5.7 7.2 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KND86897.1 - 0.025 14.5 0.1 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 KND86897.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Methyltransf_2 PF00891.18 KND86898.1 - 2.2e-16 59.8 0.1 3.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Sugar_tr PF00083.24 KND86899.1 - 6.3e-32 111.0 24.2 1.5e-26 93.3 7.9 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KND86899.1 - 1e-23 83.9 32.1 1.4e-16 60.4 19.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KND86899.1 - 0.00056 18.6 7.3 0.00056 18.6 7.3 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein Mucin PF01456.17 KND86899.1 - 0.49 10.4 0.1 0.49 10.4 0.1 2.1 3 0 0 3 3 3 0 Mucin-like glycoprotein ABC1 PF03109.16 KND86900.1 - 5.3e-25 87.9 0.0 1e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KND86900.1 - 0.0075 16.2 0.4 0.045 13.7 0.1 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family p450 PF00067.22 KND86901.1 - 1.3e-54 185.7 0.0 1.6e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 KND86903.1 - 5.8e-11 42.8 0.0 2.6e-10 40.6 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND86903.1 - 2.1e-05 24.2 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND86903.1 - 0.019 14.3 0.0 0.045 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain LuxQ-periplasm PF09308.10 KND86903.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 LuxQ, periplasmic BNR_2 PF13088.6 KND86905.1 - 7.4e-15 55.0 0.1 1e-11 44.7 0.0 2.5 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KND86905.1 - 0.0028 17.4 22.5 0.43 10.8 0.3 6.3 5 0 0 5 5 5 3 BNR/Asp-box repeat BNR_4 PF15892.5 KND86905.1 - 0.049 13.0 0.1 0.38 10.0 0.1 2.0 1 1 0 1 1 1 0 BNR repeat-containing family member Glyco_transf_90 PF05686.12 KND86906.1 - 3.6e-09 36.0 0.1 0.00011 21.2 0.0 3.5 3 1 0 3 3 3 3 Glycosyl transferase family 90 AMP-binding PF00501.28 KND86907.1 - 0 2209.7 3.7 1.5e-76 257.7 0.1 10.3 10 0 0 10 10 10 10 AMP-binding enzyme Condensation PF00668.20 KND86907.1 - 0 1475.4 0.0 2.8e-49 168.0 0.0 10.4 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.25 KND86907.1 - 4.6e-126 411.3 27.5 5.7e-13 49.0 0.2 12.5 12 0 0 12 12 12 11 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 KND86907.1 - 1.6e-39 135.6 0.0 3.8e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 KND86907.1 - 1.4e-07 32.4 0.1 0.26 12.3 0.0 7.7 9 0 0 9 9 9 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 KND86907.1 - 6.7e-05 22.5 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 KND86907.1 - 0.0026 17.7 0.0 7.7 6.3 0.0 4.5 4 0 0 4 4 4 1 alpha/beta hydrolase fold 3Beta_HSD PF01073.19 KND86907.1 - 0.15 11.1 1.1 2.9 6.8 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Thioesterase PF00975.20 KND86908.1 - 8.3e-08 32.6 0.6 1.1e-07 32.2 0.1 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KND86908.1 - 8.7e-07 29.8 0.5 1e-06 29.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family TsaE PF02367.17 KND86908.1 - 0.18 11.8 0.0 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE tRNA-synt_2c PF01411.19 KND86910.1 - 1.4e-13 50.3 0.0 1.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KND86910.1 - 6.6e-05 22.9 0.4 0.00012 22.0 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Lactamase_B_2 PF12706.7 KND86911.1 - 2.5e-26 92.4 0.3 5.3e-25 88.1 0.3 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KND86911.1 - 1.6e-09 37.8 0.0 4.2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KND86911.1 - 0.0008 19.5 0.1 0.0025 17.8 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Aminotran_4 PF01063.19 KND86912.1 - 1.3e-17 64.4 0.0 1.7e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Bac_rhamnosid_C PF17390.2 KND86912.1 - 0.07 12.9 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain bZIP_1 PF00170.21 KND86913.1 - 0.0027 17.7 8.1 0.0027 17.7 8.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KND86913.1 - 0.16 12.0 9.0 0.34 11.0 9.0 1.6 1 0 0 1 1 1 0 Basic region leucine zipper TB2_DP1_HVA22 PF03134.19 KND86914.1 - 5.1e-26 90.4 7.0 8.2e-26 89.8 7.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mgm101p PF06420.12 KND86915.1 - 6.7e-84 279.6 0.0 8.7e-84 279.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Dynamin_N PF00350.23 KND86916.1 - 4.5e-19 69.1 0.3 1.8e-18 67.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KND86916.1 - 1.1e-10 41.5 0.0 7.6e-10 38.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND86916.1 - 2.1e-07 30.7 1.6 1.7e-06 27.7 1.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KND86916.1 - 0.0073 15.9 0.3 0.064 12.9 0.4 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PMEI PF04043.15 KND86916.1 - 0.0078 16.6 1.2 0.017 15.5 0.2 2.1 2 0 0 2 2 1 1 Plant invertase/pectin methylesterase inhibitor Sigma54_activat PF00158.26 KND86916.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 KND86916.1 - 0.021 14.7 0.3 5.5 6.9 0.1 2.8 2 1 0 2 2 2 0 RsgA GTPase Lipase_GDSL_3 PF14606.6 KND86916.1 - 0.028 14.5 0.9 5.7 7.0 0.0 3.3 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family Roc PF08477.13 KND86916.1 - 0.032 14.4 0.1 1.3 9.2 0.0 2.7 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1184 PF06683.11 KND86916.1 - 0.041 13.4 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) TsaE PF02367.17 KND86916.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FoP_duplication PF13865.6 KND86916.1 - 0.078 13.5 1.3 0.18 12.4 1.3 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 AAA_29 PF13555.6 KND86916.1 - 0.081 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KND86916.1 - 0.091 13.3 0.0 0.29 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Prominin PF05478.11 KND86916.1 - 0.2 9.5 3.1 0.17 9.8 0.2 1.9 2 0 0 2 2 2 0 Prominin Laminin_I PF06008.14 KND86916.1 - 0.28 10.9 6.3 0.58 9.8 0.7 2.4 2 0 0 2 2 2 0 Laminin Domain I DASH_Dad3 PF08656.10 KND86916.1 - 0.93 9.6 4.8 2.1 8.5 0.4 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad3 IFT57 PF10498.9 KND86916.1 - 1 8.3 6.3 0.2 10.6 0.8 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2951 PF11166.8 KND86916.1 - 5.4 7.3 6.5 12 6.2 0.2 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF2951) DUF883 PF05957.13 KND86916.1 - 9.6 6.9 11.2 5.1 7.8 0.4 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Sulfotransfer_4 PF17784.1 KND86917.1 - 7.1e-15 55.4 0.0 6.2e-11 42.5 0.2 2.1 1 1 1 2 2 2 2 Sulfotransferase domain WSC PF01822.19 KND86918.1 - 3.3e-10 40.0 3.7 3.3e-10 40.0 3.7 2.9 2 1 0 2 2 2 1 WSC domain Meth_synt_2 PF01717.18 KND86919.1 - 7.7e-16 58.3 0.0 2.3e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KND86919.1 - 0.00055 19.5 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Methyltransf_23 PF13489.6 KND86921.1 - 1.5e-12 47.7 0.0 2.8e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86921.1 - 4.7e-09 36.8 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND86921.1 - 6.5e-09 35.8 0.0 1.3e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND86921.1 - 5.1e-07 30.2 0.0 1.6e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND86921.1 - 1.8e-05 25.4 0.0 0.00015 22.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KND86921.1 - 0.0085 16.2 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KND86921.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KND86921.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ABC2_membrane PF01061.24 KND86922.1 - 1.4e-72 243.5 56.7 1.1e-37 129.6 20.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KND86922.1 - 1.1e-34 119.9 0.0 7.4e-16 58.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KND86922.1 - 2.1e-28 98.1 0.1 1.7e-23 82.3 0.0 3.3 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KND86922.1 - 3.9e-14 53.0 1.9 5.7e-14 52.5 0.0 2.3 3 0 0 3 3 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KND86922.1 - 7.2e-07 29.7 0.1 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KND86922.1 - 8.7e-07 29.2 0.0 0.0079 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KND86922.1 - 1.7e-06 28.1 0.0 0.033 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KND86922.1 - 0.00012 22.6 0.2 0.033 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND86922.1 - 0.00013 21.7 0.3 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KND86922.1 - 0.00013 22.5 0.0 0.063 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND86922.1 - 0.0002 21.3 0.1 0.0024 17.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KND86922.1 - 0.00039 20.1 0.1 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KND86922.1 - 0.0012 19.2 0.1 0.48 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 KND86922.1 - 0.0013 18.4 1.7 0.14 11.7 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KND86922.1 - 0.0035 17.6 0.0 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND86922.1 - 0.0064 16.4 1.2 3.1 7.7 0.1 2.4 2 0 0 2 2 2 2 NACHT domain ABC2_membrane_3 PF12698.7 KND86922.1 - 0.009 15.2 36.0 0.021 13.9 9.2 2.7 2 1 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.19 KND86922.1 - 0.011 15.1 0.0 0.95 8.8 0.0 3.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KND86922.1 - 0.03 14.0 0.4 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KND86922.1 - 0.11 11.8 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TsaE PF02367.17 KND86922.1 - 0.12 12.4 0.6 6.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 KND86922.1 - 0.14 12.6 0.2 25 5.3 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KND86922.1 - 0.31 11.5 1.0 0.58 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KND86922.1 - 0.32 10.7 0.7 24 4.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Methyltransf_16 PF10294.9 KND86923.1 - 9.6e-29 100.3 0.0 6.6e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KND86923.1 - 2.3e-07 30.8 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND86923.1 - 0.0025 17.4 0.0 0.062 12.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KND86923.1 - 0.014 16.1 0.0 0.037 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KND86924.1 - 1.7e-15 57.2 0.0 3.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND86924.1 - 1.8e-09 38.1 0.0 0.0011 19.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KND86924.1 - 1.8e-08 34.9 0.0 4.3e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KND86924.1 - 3.5e-06 27.7 0.0 0.0024 18.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KND86924.1 - 1.7e-05 24.7 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 KND86924.1 - 0.0021 17.6 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KND86924.1 - 0.092 12.1 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KND86924.1 - 0.1 12.1 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.20 KND86924.1 - 0.15 11.3 0.0 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KND86924.1 - 0.18 11.2 0.0 1.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) AMP-binding PF00501.28 KND86927.1 - 2.2e-69 234.1 0.0 3.1e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND86927.1 - 4e-05 24.5 0.1 0.00012 23.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 KND86927.1 - 0.0027 16.4 0.0 0.2 10.3 0.1 2.1 2 0 0 2 2 2 2 Condensation domain p450 PF00067.22 KND86928.1 - 2e-59 201.6 0.1 6.9e-31 107.5 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Arylsulfotran_2 PF14269.6 KND86929.1 - 3.5e-48 164.5 1.6 4.6e-48 164.1 1.6 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KND86929.1 - 1.4e-20 73.6 0.1 3.1e-20 72.4 0.1 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Pex24p PF06398.11 KND86931.1 - 8.3e-95 317.9 0.1 1e-94 317.5 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Syntaxin-18_N PF10496.9 KND86931.1 - 0.18 12.1 1.7 0.43 10.9 0.3 2.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus TPR_1 PF00515.28 KND86933.1 - 2.7e-19 68.1 0.0 1.5e-05 24.6 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND86933.1 - 6.9e-18 63.3 1.3 0.0021 18.1 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND86933.1 - 6.3e-16 57.2 0.0 5.2e-05 23.1 0.0 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KND86933.1 - 3.4e-12 46.1 3.6 0.1 13.5 0.0 5.8 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND86933.1 - 5.9e-10 39.3 6.4 1.8e-05 25.0 0.5 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND86933.1 - 3.9e-09 35.9 7.9 0.016 15.2 0.1 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC8 PF04049.13 KND86933.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 KND86933.1 - 4.3e-08 32.7 0.7 3.4e-06 26.6 0.0 3.4 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.6 KND86933.1 - 1.1e-07 32.4 1.8 3.8e-05 24.3 0.3 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND86933.1 - 2.4e-06 27.6 0.8 0.039 14.2 0.1 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KND86933.1 - 1.9e-05 25.1 0.7 0.035 14.6 0.0 3.8 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KND86933.1 - 0.0006 19.6 3.3 1.7 8.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KND86933.1 - 0.0022 18.1 1.5 0.29 11.3 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND86933.1 - 0.012 15.9 0.0 16 6.1 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KND86933.1 - 0.017 14.4 0.5 1.6 7.9 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND86933.1 - 0.61 10.8 9.5 42 5.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_18 PF13238.6 KND86934.1 - 2.4e-05 24.9 0.1 0.00019 22.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KND86934.1 - 3e-05 23.8 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 KND86934.1 - 8.5e-05 22.4 0.3 0.0002 21.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND86934.1 - 0.00042 20.5 1.2 0.0063 16.7 1.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND86934.1 - 0.00051 20.3 0.0 0.00083 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KND86934.1 - 0.0008 18.7 0.3 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KND86934.1 - 0.00086 19.7 0.1 0.0014 19.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KND86934.1 - 0.0012 19.2 0.1 0.0017 18.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KND86934.1 - 0.0012 19.3 0.0 0.0025 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KND86934.1 - 0.0013 18.0 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_11 PF13086.6 KND86934.1 - 0.0041 16.9 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KND86934.1 - 0.0042 16.7 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KND86934.1 - 0.0058 16.6 0.1 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 KND86934.1 - 0.0085 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KND86934.1 - 0.0086 16.0 0.0 0.021 14.8 0.0 1.6 1 1 1 2 2 2 1 NACHT domain T2SSE PF00437.20 KND86934.1 - 0.0098 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 KND86934.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND86934.1 - 0.012 15.6 0.0 0.072 13.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KND86934.1 - 0.018 15.5 0.3 0.077 13.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KND86934.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KND86934.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND86934.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 KND86934.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 KND86934.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KND86934.1 - 0.082 13.2 0.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KND86934.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 KND86934.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KND86934.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KND86934.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 KND86935.1 - 1.2e-10 42.0 0.0 2.4e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 KND86936.1 - 1.2e-16 60.9 0.0 4.9e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND86936.1 - 5.4e-13 48.8 0.0 1.9e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND86936.1 - 3.4e-05 23.3 0.0 5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND86936.1 - 0.046 13.7 0.1 0.065 13.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4757 PF15949.5 KND86938.1 - 0.024 15.1 0.2 0.038 14.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) Adeno_E1B_55K_N PF04623.12 KND86939.1 - 0.19 12.4 3.7 3.1 8.6 2.1 3.0 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus DAHP_synth_1 PF00793.20 KND86941.1 - 4.3e-102 340.7 0.1 5.4e-102 340.4 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.9 KND86943.1 - 1.5e-13 50.9 0.0 2.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S zf_C2HC_14 PF18574.1 KND86944.1 - 0.039 13.7 2.5 0.087 12.6 2.5 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain Arm PF00514.23 KND86945.1 - 0.14 12.2 5.8 4.1 7.6 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Pam16 PF03656.13 KND86946.1 - 1.5e-30 105.8 0.1 1.8e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Pam16 COX14 PF14880.6 KND86947.1 - 8.2e-18 64.0 0.5 8.2e-18 64.0 0.5 1.7 2 0 0 2 2 2 1 Cytochrome oxidase c assembly PRP4 PF08799.11 KND86947.1 - 0.027 14.0 0.3 0.062 12.9 0.3 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Cas_Cas02710 PF09670.10 KND86947.1 - 0.053 12.3 0.1 0.073 11.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DLEU7 PF15760.5 KND86947.1 - 0.62 9.5 3.9 0.15 11.6 0.2 1.8 2 0 0 2 2 2 0 Leukemia-associated protein 7 Ribosomal_L13e PF01294.18 KND86948.1 - 5e-76 254.6 2.8 6.2e-76 254.3 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e BPL_N PF09825.9 KND86949.1 - 2.5e-141 471.1 0.0 3.2e-141 470.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KND86949.1 - 4.1e-18 65.6 0.0 6.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.13 KND86950.1 - 0.0015 18.6 8.9 0.0026 17.8 8.9 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KND86950.1 - 0.0096 15.9 1.1 0.082 12.9 0.3 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 KND86950.1 - 0.041 14.2 2.9 0.057 13.8 2.9 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KND86950.1 - 0.051 13.6 5.1 0.28 11.2 5.1 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GT-D PF08759.11 KND86950.1 - 0.052 13.2 0.0 0.059 13.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold p450 PF00067.22 KND86951.1 - 1.2e-53 182.5 0.0 1.5e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FeS_assembly_P PF01883.19 KND86951.1 - 0.14 12.3 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein DPM3 PF08285.11 KND86952.1 - 1.7e-36 124.3 0.1 1.8e-36 124.2 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.9 KND86954.1 - 5.2e-25 86.9 3.9 5.2e-25 86.9 3.9 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Fungal_trans PF04082.18 KND86955.1 - 3.4e-16 59.1 0.0 5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86955.1 - 4e-06 26.9 12.8 6.6e-06 26.2 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KND86955.1 - 0.0053 16.9 4.9 0.011 15.9 4.9 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain DPM3 PF08285.11 KND86957.1 - 1.7e-36 124.3 0.1 1.8e-36 124.2 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3669 PF12417.8 KND86959.1 - 0.0001 22.4 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein PAT1 PF09770.9 KND86959.1 - 0.71 8.1 8.9 0.99 7.6 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 KND86959.1 - 1.1 9.1 10.3 1.6 8.7 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pribosyltran PF00156.27 KND86960.1 - 4.8e-07 29.4 0.0 7.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Tfb2 PF03849.14 KND86961.1 - 2e-134 448.1 0.0 2.4e-134 447.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KND86961.1 - 1.5e-20 73.4 0.4 2.8e-20 72.5 0.4 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KND86961.1 - 0.0015 18.7 0.1 0.004 17.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TANGO2 PF05742.12 KND86962.1 - 5.3e-64 216.7 0.0 6.1e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 4HBT PF03061.22 KND86963.1 - 8.3e-15 54.9 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KND86963.1 - 0.00014 22.0 0.0 0.00022 21.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 7tm_3 PF00003.22 KND86964.1 - 0.027 14.2 18.4 0.06 13.1 18.7 1.4 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR RTA1 PF04479.13 KND86964.1 - 3.4 7.2 12.9 0.29 10.7 7.3 2.0 1 1 1 2 2 2 0 RTA1 like protein DUF1345 PF07077.11 KND86964.1 - 6.5 6.4 14.5 0.78 9.4 2.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1345) DUF2569 PF10754.9 KND86964.1 - 7.3 7.0 15.8 0.18 12.3 3.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2569) HTH_43 PF09904.9 KND86965.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Peptidase_S10 PF00450.22 KND86967.1 - 3.5e-75 254.0 0.0 4.5e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase FA_hydroxylase PF04116.13 KND86967.1 - 2.4e-20 73.2 12.2 2.4e-20 73.2 12.2 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily MAGUK_N_PEST PF10608.9 KND86968.1 - 0.016 15.7 0.9 0.12 12.9 0.9 2.1 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Aspzincin_M35 PF14521.6 KND86969.1 - 4.2e-22 79.3 0.5 4.6e-22 79.1 0.5 1.0 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KND86969.1 - 2.9e-21 75.7 1.9 3e-21 75.7 1.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family COG4 PF08318.12 KND86971.1 - 1.3e-111 372.9 0.0 2e-111 372.3 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Choline_transpo PF04515.12 KND86972.1 - 4.1e-79 266.1 25.2 4.1e-79 266.1 25.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4131 PF13567.6 KND86972.1 - 0.016 14.9 0.3 0.016 14.9 0.3 5.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4131) APG17 PF04108.12 KND86973.1 - 6.1e-122 407.5 7.7 8.4e-122 407.1 7.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF2103 PF09876.9 KND86973.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2103) ABC_tran_CTD PF16326.5 KND86973.1 - 0.15 12.3 2.1 0.35 11.1 0.3 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Peptidase_C2 PF00648.21 KND86974.1 - 3.3e-56 190.5 0.4 8.2e-55 185.9 0.4 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Macoilin PF09726.9 KND86974.1 - 3.6 6.0 16.0 9.3 4.7 16.0 1.7 1 0 0 1 1 1 0 Macoilin family MCM_bind PF09739.9 KND86974.1 - 5.5 5.3 14.7 9 4.6 11.9 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor AMP-binding PF00501.28 KND86975.1 - 2.1e-74 250.6 0.0 4.1e-74 249.7 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KND86975.1 - 3.5e-62 209.9 0.0 1.7e-61 207.7 0.0 2.1 3 0 0 3 3 3 1 Male sterility protein adh_short PF00106.25 KND86975.1 - 2.6e-52 177.1 4.3 5.3e-52 176.1 3.8 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND86975.1 - 6.3e-40 137.2 5.2 8.6e-40 136.7 4.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KND86975.1 - 4.5e-19 68.9 0.4 6.5e-11 42.2 0.0 4.0 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family KR PF08659.10 KND86975.1 - 1.6e-16 60.7 3.0 1.2e-13 51.4 2.5 2.4 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 KND86975.1 - 2.2e-12 47.2 0.0 5.4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KND86975.1 - 7.2e-08 32.5 1.0 5.7e-07 29.6 1.3 2.3 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KND86975.1 - 2e-06 27.2 0.8 0.0075 15.4 0.3 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein AMP-binding_C PF13193.6 KND86975.1 - 3.9e-05 24.5 1.9 0.00036 21.5 0.2 3.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KND86975.1 - 9.6e-05 21.6 0.3 0.0045 16.1 0.0 2.9 3 1 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KND86975.1 - 0.00092 18.3 0.0 0.014 14.4 0.0 2.5 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.16 KND86975.1 - 0.016 14.9 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 KND86975.1 - 0.035 13.9 6.1 0.016 15.0 2.9 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein HD_6 PF18019.1 KND86976.1 - 0.034 14.3 2.1 0.062 13.4 2.1 1.3 1 0 0 1 1 1 0 HD domain Ribosomal_L15e PF00827.17 KND86976.1 - 0.26 11.0 1.7 2 8.1 0.6 2.3 2 0 0 2 2 2 0 Ribosomal L15 AA_permease PF00324.21 KND86977.1 - 5e-132 440.9 52.1 6e-132 440.6 52.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND86977.1 - 1.3e-31 109.9 55.8 1.8e-31 109.4 55.8 1.2 1 0 0 1 1 1 1 Amino acid permease TssO PF17561.2 KND86977.1 - 9.9 6.3 6.1 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO Fungal_trans PF04082.18 KND86978.1 - 2.5e-16 59.5 1.0 4.4e-16 58.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND86978.1 - 3.1e-08 33.6 13.4 7.8e-08 32.3 13.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SKA2 PF16740.5 KND86978.1 - 0.11 12.2 0.2 11 5.9 0.0 3.3 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 RdRP PF05183.12 KND86979.1 - 3.3e-125 419.0 0.0 4.3e-125 418.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase zf-RING_UBOX PF13445.6 KND86980.1 - 9.5e-05 22.3 2.3 0.0003 20.8 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KND86980.1 - 0.0042 16.9 7.1 0.013 15.3 7.1 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KND86980.1 - 0.0047 16.8 6.4 0.013 15.4 5.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND86980.1 - 0.039 13.8 0.2 0.039 13.8 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) HTH_17 PF12728.7 KND86980.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-RING_5 PF14634.6 KND86980.1 - 1.4 8.9 15.1 0.7 9.9 10.7 2.8 2 1 0 2 2 2 0 zinc-RING finger domain UPF0052 PF01933.18 KND86981.1 - 9.7e-61 205.6 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cwf_Cwc_15 PF04889.12 KND86981.1 - 3.8 7.2 12.7 0.71 9.6 8.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ADH_zinc_N PF00107.26 KND86982.1 - 4.9e-28 97.7 0.7 8.3e-28 97.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND86982.1 - 6.5e-17 62.8 0.0 2.4e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND86982.1 - 2.4e-09 37.1 0.0 4.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KND86982.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ADH_N_2 PF16884.5 KND86982.1 - 0.0077 16.1 0.0 0.018 14.9 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase NicO PF03824.16 KND86983.1 - 1.4e-45 155.9 0.9 1.4e-45 155.9 0.9 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein VirB3 PF05101.13 KND86983.1 - 3.1 8.1 14.7 0.62 10.3 0.5 3.4 3 1 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein CFEM PF05730.11 KND86985.1 - 4.5e-29 100.3 57.0 1.7e-09 37.6 13.5 3.7 3 0 0 3 3 3 3 CFEM domain DUF3437 PF11919.8 KND86985.1 - 0.52 10.2 2.1 8.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) 4HBT PF03061.22 KND86986.1 - 6.2e-14 52.1 1.1 6.2e-14 52.1 1.1 1.9 2 1 1 3 3 3 1 Thioesterase superfamily 4HBT_3 PF13622.6 KND86986.1 - 0.0038 17.5 0.2 0.0049 17.2 0.2 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyoxalase_3 PF13468.6 KND86987.1 - 1.8e-23 83.5 0.1 3.2e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain BTB PF00651.31 KND86987.1 - 0.00017 21.8 0.0 0.00037 20.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_S7e PF01251.18 KND86991.1 - 4.2e-83 277.6 0.2 4.9e-83 277.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e WSC PF01822.19 KND86992.1 - 1.4e-07 31.6 4.8 2.7e-07 30.7 4.8 1.5 1 0 0 1 1 1 1 WSC domain Hydantoinase_B PF02538.14 KND86993.1 - 2.3e-202 673.0 1.1 3.2e-202 672.5 1.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KND86993.1 - 1.4e-98 329.8 0.4 1e-97 326.9 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KND86993.1 - 4.2e-56 189.5 0.1 2.6e-54 183.6 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Pyr_redox_2 PF07992.14 KND86993.1 - 0.055 12.7 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 KND86994.1 - 1.5e-31 109.6 22.4 1.5e-31 109.6 22.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MLANA PF14991.6 KND86994.1 - 0.069 13.4 0.0 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein melan-A Abhydrolase_4 PF08386.10 KND86996.1 - 9.7e-11 41.7 0.0 1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein DUF563 PF04577.14 KND86997.1 - 1.5e-34 119.9 0.0 2.7e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) FAD_binding_4 PF01565.23 KND86997.1 - 9e-24 83.8 2.8 2.2e-23 82.6 2.8 1.7 1 0 0 1 1 1 1 FAD binding domain Mito_carr PF00153.27 KND86998.1 - 3.6e-68 225.6 0.5 1.5e-21 76.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 KND86999.1 - 1.2e-34 118.7 0.0 7e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4275 PF14101.6 KND87001.1 - 0.054 13.6 0.7 0.09 12.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) polyprenyl_synt PF00348.17 KND87002.1 - 8.2e-12 44.7 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RIO1 PF01163.22 KND87003.1 - 6.4e-69 231.3 0.3 1.7e-68 229.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 KND87003.1 - 0.0021 18.0 0.1 2.4 8.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family NmrA PF05368.13 KND87004.1 - 2.3e-05 24.1 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KND87004.1 - 0.00041 20.6 0.0 0.00063 20.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KND87004.1 - 0.00045 20.3 0.2 0.00097 19.2 0.2 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Asp PF00026.23 KND87005.1 - 1.8e-58 198.4 0.8 2.1e-58 198.2 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND87005.1 - 2.9e-09 37.4 0.2 2e-07 31.4 0.2 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KND87005.1 - 0.038 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF924 PF06041.11 KND87006.1 - 4.6e-43 147.4 0.0 1.2e-40 139.5 0.0 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Dynactin_p62 PF05502.13 KND87008.1 - 4.3e-204 678.7 2.3 1.1e-203 677.4 2.3 1.5 1 1 0 1 1 1 1 Dynactin p62 family Golgin_A5 PF09787.9 KND87009.1 - 0.057 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HALZ PF02183.18 KND87009.1 - 0.07 13.4 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cep57_MT_bd PF06657.13 KND87009.1 - 0.24 11.9 0.1 0.24 11.9 0.1 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 G-alpha PF00503.20 KND87010.1 - 0.13 11.4 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ICL PF00463.21 KND87011.1 - 5.8e-118 394.7 0.3 6.9e-118 394.4 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Aminotran_1_2 PF00155.21 KND87012.1 - 2.1e-12 46.9 0.0 3.9e-12 46.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KND87012.1 - 0.044 12.6 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase GATase PF00117.28 KND87013.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.7 1 1 0 1 1 1 0 Glutamine amidotransferase class-I GATase_3 PF07685.14 KND87013.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Zn_clus PF00172.18 KND87014.1 - 1e-08 35.1 8.7 2e-08 34.2 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND87014.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ILVD_EDD PF00920.21 KND87015.1 - 5.9e-134 447.5 3.2 2.1e-81 274.1 1.7 2.0 1 1 1 2 2 2 2 Dehydratase family Methyltransf_23 PF13489.6 KND87017.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87017.1 - 5.4e-09 36.6 0.0 3.2e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87017.1 - 6.9e-08 33.1 0.0 1.1e-06 29.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87017.1 - 1.7e-06 28.6 0.0 4e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87017.1 - 0.0013 18.5 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 KND87017.1 - 0.0099 15.2 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 KND87017.1 - 0.051 12.9 0.0 2.6 7.3 0.0 2.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KND87017.1 - 0.053 12.9 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KND87017.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ldh_2 PF02615.14 KND87018.1 - 1.8e-120 402.1 2.3 2e-120 401.9 2.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase APH PF01636.23 KND87019.1 - 6.8e-09 36.0 0.0 1.4e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87019.1 - 8e-07 28.9 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Asp PF00026.23 KND87021.1 - 6e-06 25.9 0.0 8.4e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 KND87021.1 - 0.00068 18.6 0.5 0.001 18.0 0.5 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein Beta-APP PF03494.13 KND87021.1 - 0.086 12.7 3.2 0.21 11.4 3.2 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) WD40 PF00400.32 KND87022.1 - 2.8e-44 148.2 20.1 5.1e-08 33.5 0.1 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87022.1 - 6.3e-12 45.6 0.5 0.00068 19.9 0.0 6.0 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KND87022.1 - 1e-10 41.3 0.8 2.4e-10 40.1 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND87022.1 - 7.8e-10 38.4 0.4 1.8e-09 37.2 0.4 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KND87022.1 - 1.2e-09 37.4 6.7 0.041 12.5 0.1 4.3 1 1 2 4 4 4 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 KND87022.1 - 0.0018 18.1 0.1 0.0058 16.5 0.1 1.9 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 KND87022.1 - 0.0067 15.8 0.1 0.04 13.2 0.2 2.0 2 0 0 2 2 2 1 WD40-like domain PALB2_WD40 PF16756.5 KND87022.1 - 0.015 14.2 1.9 8.9 5.1 0.1 3.4 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cupin_2 PF07883.11 KND87024.1 - 2.2e-05 24.1 0.3 0.17 11.6 0.2 2.7 2 1 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KND87024.1 - 0.12 12.3 0.1 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain CFEM PF05730.11 KND87025.1 - 0.00044 20.3 1.6 0.00071 19.6 1.6 1.4 1 0 0 1 1 1 1 CFEM domain GPS PF01825.21 KND87025.1 - 0.069 13.7 0.5 0.14 12.7 0.5 1.6 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif SMYLE_N PF18615.1 KND87025.1 - 0.14 11.6 1.5 0.17 11.4 1.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain APH PF01636.23 KND87027.1 - 2.8e-06 27.5 0.3 1.7e-05 24.9 0.2 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87027.1 - 0.0021 17.7 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND87027.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Aminotran_5 PF00266.19 KND87028.1 - 5.3e-31 107.9 0.0 7.3e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V zf-UBP_var PF17807.1 KND87030.1 - 0.1 12.4 1.2 0.66 9.8 0.1 2.5 3 0 0 3 3 3 0 Variant UBP zinc finger Kelch_6 PF13964.6 KND87030.1 - 0.26 11.7 6.4 1.4 9.3 1.2 3.5 3 0 0 3 3 3 0 Kelch motif peroxidase PF00141.23 KND87031.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Peroxidase NCOA_u2 PF16665.5 KND87031.1 - 0.72 10.2 5.0 0.24 11.7 1.1 2.1 1 1 1 2 2 2 0 Unstructured region on nuclear receptor coactivator protein Retrotrans_gag PF03732.17 KND87032.1 - 4.4e-06 26.9 0.0 9.8e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4919 PF16266.5 KND87034.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) Nsp1_C PF05064.13 KND87035.1 - 0.038 13.8 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region PAP2_C PF14360.6 KND87037.1 - 0.16 12.5 3.6 0.5 11.0 0.2 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF1774 PF08611.10 KND87038.1 - 1.4e-23 83.1 1.5 2.3e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) SIT PF15330.6 KND87038.1 - 0.0043 17.5 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT QueF PF14489.6 KND87039.1 - 0.17 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 QueF-like protein WD40 PF00400.32 KND87041.1 - 4.1e-29 100.2 10.6 6.2e-08 33.2 0.1 6.0 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87041.1 - 1.4e-07 31.7 0.0 0.0025 18.1 0.0 3.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KND87041.1 - 0.011 15.1 0.1 0.67 9.2 0.0 2.9 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KND87041.1 - 0.027 13.4 0.0 6.6 5.6 0.0 2.5 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KND87041.1 - 0.036 12.7 0.3 0.4 9.3 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 AA_permease_2 PF13520.6 KND87042.1 - 1.2e-41 143.0 53.5 1.5e-41 142.7 53.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND87042.1 - 3.7e-25 88.5 49.1 5e-25 88.0 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 KND87042.1 - 0.31 10.9 0.4 0.64 9.9 0.4 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Cofilin_ADF PF00241.20 KND87043.1 - 4.7e-22 78.1 0.0 5.2e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CagE_TrbE_VirB PF03135.14 KND87043.1 - 0.16 12.1 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system HhH-GPD PF00730.25 KND87044.1 - 6.2e-19 68.4 0.0 1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KND87044.1 - 1e-17 64.1 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.23 KND87044.1 - 1.8e-06 27.5 0.1 4.7e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SBF PF01758.16 KND87046.1 - 2.1e-26 92.8 4.4 4e-26 91.9 4.4 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 KND87046.1 - 6.5e-06 25.7 8.0 8.4e-06 25.3 8.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Sugar_tr PF00083.24 KND87048.1 - 8.2e-10 38.1 0.2 6.7e-07 28.5 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter CBM_21 PF03370.13 KND87049.1 - 2.5e-34 117.8 0.1 4e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KND87049.1 - 2.3e-10 40.9 0.3 4.5e-10 40.0 0.3 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) APH PF01636.23 KND87050.1 - 2e-07 31.2 1.6 8.7e-06 25.8 1.6 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Stb3 PF10330.9 KND87050.1 - 0.041 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative Sin3 binding protein INO80_Ies4 PF08193.11 KND87051.1 - 0.0052 16.8 0.5 0.0085 16.1 0.5 1.4 1 0 0 1 1 1 1 INO80 complex subunit Ies4 SKG6 PF08693.10 KND87051.1 - 0.017 14.5 1.4 0.017 14.5 1.4 2.4 3 0 0 3 3 3 0 Transmembrane alpha-helix domain APH PF01636.23 KND87053.1 - 3.2e-21 76.3 0.1 4.1e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87053.1 - 4.9e-05 23.0 0.0 6.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND87053.1 - 6.7e-05 22.6 0.0 0.0033 17.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KND87053.1 - 0.001 18.5 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KND87053.1 - 0.0082 15.5 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KND87053.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase FAD_binding_4 PF01565.23 KND87053.1 - 0.17 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 KND87054.1 - 3.5e-22 78.8 33.7 3.5e-22 78.8 33.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 KND87055.1 - 5.9e-76 255.8 10.7 9e-76 255.2 10.7 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KND87055.1 - 4.3e-06 25.9 24.0 4.7e-05 22.5 9.9 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily p450 PF00067.22 KND87056.1 - 5.4e-57 193.6 0.0 1.6e-56 192.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Brix PF04427.18 KND87057.1 - 2.1e-29 103.0 0.0 2.7e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glyco_hydro_47 PF01532.20 KND87058.1 - 1.4e-163 545.1 0.0 1.6e-163 544.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_1 PF00515.28 KND87059.1 - 1.2e-44 148.3 9.2 1e-05 25.1 0.0 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 KND87059.1 - 1.9e-43 143.1 8.3 0.00021 21.2 0.0 11.4 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 KND87059.1 - 1.3e-26 90.5 16.1 0.00033 20.6 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 KND87059.1 - 2.5e-26 90.1 3.8 7.8e-05 22.8 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 KND87059.1 - 3.5e-25 88.4 0.3 1.7e-05 25.3 0.0 6.4 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KND87059.1 - 1.5e-21 76.4 17.2 0.0003 21.0 0.6 7.7 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 KND87059.1 - 5.3e-19 68.5 10.5 1.1e-05 25.9 1.0 6.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND87059.1 - 2.3e-17 62.4 12.8 3.6e-05 23.4 0.0 8.0 7 1 2 9 9 8 4 TPR repeat TPR_14 PF13428.6 KND87059.1 - 3.9e-17 61.5 5.5 0.00045 20.8 0.0 8.7 3 2 6 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 KND87059.1 - 1.1e-15 57.5 1.8 0.00057 20.0 0.0 6.4 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 KND87059.1 - 7.6e-13 47.5 5.1 0.035 14.1 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KND87059.1 - 1.7e-08 34.2 0.4 8.2e-07 28.7 0.4 2.6 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 KND87059.1 - 4.8e-07 29.4 16.4 0.075 12.9 0.6 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND87059.1 - 1.8e-06 28.0 7.6 0.014 15.6 0.4 5.5 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KND87059.1 - 2.9e-06 26.6 2.0 0.12 11.9 0.0 4.9 4 0 0 4 4 4 1 SHNi-TPR MAS20 PF02064.15 KND87059.1 - 0.00031 20.8 10.4 0.014 15.5 0.5 4.7 4 1 1 5 5 5 1 MAS20 protein import receptor TPR_6 PF13174.6 KND87059.1 - 0.00051 20.5 21.1 0.3 11.8 0.0 8.6 10 0 0 10 10 8 1 Tetratricopeptide repeat DUF3856 PF12968.7 KND87059.1 - 0.0019 18.3 2.4 4.2 7.4 0.0 5.0 3 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 KND87059.1 - 0.0021 17.1 0.3 0.021 13.7 0.1 4.8 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 PknG_TPR PF16918.5 KND87059.1 - 0.0055 15.5 0.0 0.027 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat HemY_N PF07219.13 KND87059.1 - 0.015 15.5 3.4 11 6.2 0.0 5.3 4 2 1 5 5 5 0 HemY protein N-terminus HrpB1_HrpK PF09613.10 KND87059.1 - 0.025 14.2 0.3 0.4 10.3 0.6 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 KND87059.1 - 0.032 14.7 4.8 17 5.8 0.0 4.8 2 1 3 5 5 5 0 Bacterial transcriptional activator domain DUF1836 PF08876.11 KND87059.1 - 0.061 13.4 0.4 13 5.9 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF1836) Sel1 PF08238.12 KND87059.1 - 0.23 12.2 0.1 0.23 12.2 0.1 4.5 5 0 0 5 5 4 0 Sel1 repeat TPR_20 PF14561.6 KND87059.1 - 0.33 11.3 10.9 6.3 7.2 0.3 4.7 5 2 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 KND87059.1 - 6.2 7.0 16.9 14 5.9 0.2 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Abhydrolase_3 PF07859.13 KND87060.1 - 7.4e-06 26.0 0.0 4.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Sulfate_transp PF00916.20 KND87061.1 - 1.4e-76 257.8 11.9 2e-76 257.3 11.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND87061.1 - 1.5e-17 63.3 0.0 3.3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KND87061.1 - 0.00038 20.7 0.0 0.0013 19.1 0.0 1.9 1 0 0 1 1 1 1 STAS domain Thiolase_N PF00108.23 KND87062.1 - 2.3e-66 223.8 0.2 3e-66 223.5 0.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND87062.1 - 2.3e-39 133.8 1.8 2.7e-39 133.6 0.3 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND87062.1 - 0.0037 16.9 1.7 0.031 13.9 0.7 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KND87062.1 - 0.051 13.4 0.2 15 5.5 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Syntaxin PF00804.25 KND87063.1 - 4.8e-22 78.6 6.3 4.8e-22 78.6 6.3 1.8 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 KND87063.1 - 2.1e-12 46.9 1.8 5.4e-12 45.5 0.3 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 KND87063.1 - 3e-07 30.7 18.5 8.6e-06 26.1 6.6 2.3 2 0 0 2 2 2 2 Syntaxin-like protein RasGAP_C PF03836.15 KND87063.1 - 0.0021 18.2 1.4 0.0021 18.2 1.4 2.7 2 1 0 2 2 2 1 RasGAP C-terminus Mod_r PF07200.13 KND87063.1 - 0.0038 17.3 3.4 0.0038 17.3 3.4 2.7 2 1 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Prominin PF05478.11 KND87063.1 - 0.01 13.8 7.2 0.12 10.3 5.4 2.2 1 1 1 2 2 2 0 Prominin DUF5345 PF17280.2 KND87063.1 - 0.011 15.7 0.1 0.051 13.5 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5345) DotU PF09850.9 KND87063.1 - 0.016 14.9 0.5 0.055 13.2 0.1 2.2 2 0 0 2 2 1 0 Type VI secretion system protein DotU Use1 PF09753.9 KND87063.1 - 0.018 14.8 11.4 0.029 14.1 8.9 1.9 1 1 1 2 2 2 0 Membrane fusion protein Use1 DUF16 PF01519.16 KND87063.1 - 0.025 15.0 2.5 0.025 15.0 2.5 3.1 2 1 1 3 3 3 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 KND87063.1 - 0.041 14.3 2.7 23 5.4 0.0 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ArsA_ATPase PF02374.15 KND87063.1 - 0.048 12.8 1.2 0.9 8.7 0.0 2.1 1 1 1 2 2 2 0 Anion-transporting ATPase MCU PF04678.13 KND87063.1 - 0.072 13.2 7.2 0.28 11.2 7.0 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter T6PP_N PF18572.1 KND87063.1 - 0.091 12.6 7.3 6.1 6.7 0.0 3.3 2 1 1 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain TACC_C PF05010.14 KND87063.1 - 0.11 12.3 13.4 0.21 11.4 3.3 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CK2S PF15011.6 KND87063.1 - 0.25 11.2 8.0 1 9.3 0.5 2.9 1 1 2 3 3 3 0 Casein Kinase 2 substrate Muted PF14942.6 KND87063.1 - 0.35 11.2 12.4 0.47 10.8 2.5 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4094 PF13334.6 KND87063.1 - 0.38 11.2 4.6 1.8 9.0 0.5 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 KND87063.1 - 0.5 10.5 15.2 0.63 10.2 4.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PBP1_TM PF14812.6 KND87063.1 - 0.94 9.9 0.0 0.94 9.9 0.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ApoO PF09769.9 KND87063.1 - 1.6 8.7 5.0 22 5.0 0.2 2.8 2 1 1 3 3 3 0 Apolipoprotein O Tweety PF04906.13 KND87063.1 - 1.6 7.3 8.1 4.4 5.9 0.3 2.4 1 1 1 2 2 2 0 Tweety DUF2203 PF09969.9 KND87063.1 - 2.1 9.1 10.7 3.1 8.5 2.8 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) SKA1 PF07160.12 KND87063.1 - 2.2 8.1 11.9 0.16 11.8 4.1 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Allexi_40kDa PF05549.11 KND87063.1 - 2.2 7.7 8.8 0.75 9.3 1.1 2.4 1 1 2 3 3 3 0 Allexivirus 40kDa protein Spc7 PF08317.11 KND87063.1 - 2.3 7.0 18.5 1.4 7.7 6.1 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KND87063.1 - 2.7 5.8 16.3 0.85 7.5 10.2 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Pepsin-I3 PF06394.13 KND87063.1 - 4 7.7 6.5 37 4.6 1.9 3.3 2 1 1 3 3 3 0 Pepsin inhibitor-3-like repeated domain DUF948 PF06103.11 KND87063.1 - 5.3 7.4 7.2 16 5.8 1.5 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 KND87063.1 - 9.4 5.0 11.9 23 3.7 11.7 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein Aminotran_4 PF01063.19 KND87064.1 - 3.4e-23 82.7 0.0 6.4e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 Amino-transferase class IV Sulfate_transp PF00916.20 KND87065.1 - 1e-107 360.2 22.7 1.3e-107 359.9 22.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND87065.1 - 9.3e-09 34.9 0.0 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KND87065.1 - 0.0021 18.4 18.9 0.0082 16.5 3.5 3.1 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KND87065.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 STAS domain Glyco_hydro_17 PF00332.18 KND87066.1 - 1.7e-06 27.8 0.4 2.3e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_cc PF11790.8 KND87067.1 - 1.2e-71 241.1 0.3 1.4e-71 240.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core E1-E2_ATPase PF00122.20 KND87068.1 - 9.4e-35 119.8 18.1 2.7e-29 102.0 0.2 3.6 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND87068.1 - 6.2e-30 104.2 2.8 6.2e-30 104.2 2.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KND87068.1 - 1.3e-21 76.5 0.0 3.5e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND87068.1 - 1.2e-19 71.4 0.2 4.4e-15 56.5 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND87068.1 - 3.7e-14 52.1 0.1 8.9e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND87068.1 - 2.9e-07 30.5 0.4 1.1e-05 25.3 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.15 KND87069.1 - 5.1e-53 180.4 29.5 1.8e-39 135.8 13.2 3.2 3 0 0 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 KND87069.1 - 2.1e-19 69.6 0.2 3.3e-19 69.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-HC5HC2H PF13771.6 KND87069.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Thi4 PF01946.17 KND87071.1 - 2.8e-118 393.3 0.2 3.8e-118 392.9 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KND87071.1 - 1.5e-06 28.1 1.3 9.1e-06 25.5 1.3 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND87071.1 - 7.9e-05 22.8 0.7 0.00022 21.4 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KND87071.1 - 0.00012 21.3 0.6 0.00035 19.7 0.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KND87071.1 - 0.00074 18.8 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND87071.1 - 0.0012 18.9 0.8 0.003 17.6 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KND87071.1 - 0.0017 17.5 2.4 0.025 13.7 0.4 2.7 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 KND87071.1 - 0.016 14.6 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KND87071.1 - 0.046 12.4 0.4 0.064 11.9 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KND87071.1 - 0.055 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND87071.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KND87071.1 - 0.11 11.3 0.2 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF917 PF06032.12 KND87072.1 - 2e-108 362.4 0.7 4.6e-108 361.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 KND87072.1 - 9.1e-27 93.9 7.6 1.6e-24 86.6 0.4 3.8 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 KND87072.1 - 2.3e-22 79.6 12.4 5e-17 62.1 1.4 4.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 KND87072.1 - 5.8e-05 21.9 2.5 0.099 11.2 0.0 2.3 2 0 0 2 2 2 2 MutL protein StbA PF06406.11 KND87072.1 - 0.00052 19.4 0.2 0.57 9.4 0.1 2.5 2 0 0 2 2 2 2 StbA protein ROK PF00480.20 KND87072.1 - 0.022 14.2 0.2 0.052 13.0 0.2 1.6 1 0 0 1 1 1 0 ROK family DUF3663 PF12404.8 KND87072.1 - 0.048 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase FtsA PF14450.6 KND87072.1 - 3.3 8.2 5.1 24 5.4 0.1 3.1 2 1 0 2 2 2 0 Cell division protein FtsA APH PF01636.23 KND87073.1 - 2.1e-06 27.9 0.3 3.1e-06 27.3 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RepA_C PF04796.12 KND87073.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Plasmid encoded RepA protein Pro_CA PF00484.19 KND87075.1 - 5.6e-51 172.9 0.0 7.6e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 KND87075.1 - 0.033 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily DinB_2 PF12867.7 KND87075.1 - 0.25 11.9 0.9 0.46 11.0 0.3 1.8 1 1 1 2 2 2 0 DinB superfamily Lyase_8 PF02278.18 KND87076.1 - 6.4e-59 199.5 3.7 1.3e-58 198.5 3.7 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KND87076.1 - 4.3e-21 75.2 0.2 7.6e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KND87076.1 - 0.0086 16.5 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Isochorismatase PF00857.20 KND87077.1 - 1.4e-24 87.3 0.0 1.6e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family ThiW PF09512.10 KND87078.1 - 0.031 14.4 7.9 0.034 14.2 3.6 2.6 2 1 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) IlvGEDA_leader PF08046.11 KND87078.1 - 0.045 13.2 5.1 2.5 7.6 0.1 3.1 3 0 0 3 3 3 0 IlvGEDA operon leader peptide LapA_dom PF06305.11 KND87078.1 - 0.52 10.2 3.5 21 5.0 0.2 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Myb_DNA-bind_3 PF12776.7 KND87079.1 - 1.9e-23 83.2 0.1 3e-23 82.6 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SOG2 PF10428.9 KND87079.1 - 2.4 7.2 5.5 3.5 6.7 5.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein tify PF06200.14 KND87080.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 tify domain DUF2985 PF11204.8 KND87081.1 - 1.6e-21 76.2 3.6 2.6e-21 75.6 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) MFS_1 PF07690.16 KND87083.1 - 3.5e-51 174.2 18.8 3.5e-51 174.2 18.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87083.1 - 1e-11 44.4 4.5 1e-11 44.4 4.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND87083.1 - 9.5e-08 30.9 5.4 1.4e-07 30.3 5.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KND87083.1 - 0.0021 16.5 4.5 0.005 15.3 4.5 1.6 1 0 0 1 1 1 1 Transmembrane secretion effector ATG22 PF11700.8 KND87083.1 - 0.021 13.5 0.4 0.021 13.5 0.4 2.4 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like UCR_Fe-S_N PF10399.9 KND87083.1 - 0.025 13.9 4.4 3.2 7.2 0.7 3.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_5 PF05631.14 KND87083.1 - 0.071 12.0 4.1 0.2 10.5 1.5 2.2 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM Phage_holin_2_4 PF16082.5 KND87083.1 - 0.12 12.1 0.0 0.12 12.1 0.0 4.6 4 2 1 5 5 5 0 Bacteriophage holin family, superfamily II-like OATP PF03137.20 KND87083.1 - 0.26 9.5 7.3 1.1 7.4 2.1 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Cir_N PF10197.9 KND87083.1 - 1.9 8.7 5.5 3.7 7.8 5.5 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR V-SNARE_C PF12352.8 KND87084.1 - 5.3e-14 52.3 1.8 2e-13 50.4 0.1 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KND87084.1 - 2.8e-06 27.1 0.1 2.4e-05 24.2 0.0 2.3 2 1 1 3 3 3 1 Sec20 TPR_MLP1_2 PF07926.12 KND87084.1 - 0.012 15.7 1.9 0.45 10.6 0.3 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Mito_fiss_reg PF05308.11 KND87084.1 - 0.049 13.7 0.4 0.06 13.4 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HBM PF16591.5 KND87084.1 - 0.1 12.0 1.9 0.24 10.8 0.1 2.2 2 1 1 3 3 3 0 Helical bimodular sensor domain KxDL PF10241.9 KND87084.1 - 0.13 12.6 1.4 15 5.9 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein DivIC PF04977.15 KND87084.1 - 0.47 10.3 2.5 3.9 7.3 0.1 3.1 2 1 0 3 3 3 0 Septum formation initiator TPK_catalytic PF04263.16 KND87085.1 - 1.6e-27 96.0 0.0 2.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KND87085.1 - 8.8e-23 79.8 0.2 1.3e-22 79.3 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF5353 PF17304.2 KND87086.1 - 7.2e-12 44.9 3.8 1.3e-11 44.0 3.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) IER PF05760.12 KND87086.1 - 0.015 15.7 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) AP3D1 PF06375.11 KND87086.1 - 0.023 14.9 0.2 0.035 14.4 0.2 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Cas_csx3 PF09620.10 KND87086.1 - 0.036 13.9 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) TetR_C_34 PF17929.1 KND87086.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain G_glu_transpept PF01019.21 KND87087.1 - 1.2e-164 548.9 0.8 1.4e-164 548.7 0.8 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase 4HBT_2 PF13279.6 KND87088.1 - 2.7e-23 82.8 0.1 4.3e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily ADH_N_2 PF16884.5 KND87089.1 - 1.4e-29 102.2 0.0 2.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KND87089.1 - 3.3e-19 69.1 0.0 4.9e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND87089.1 - 3.8e-06 28.0 0.0 6.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3139 PF11337.8 KND87090.1 - 0.092 13.4 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) FmdA_AmdA PF03069.15 KND87091.1 - 1.3e-172 573.8 0.0 1.5e-172 573.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family B3_4 PF03483.17 KND87091.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 B3/4 domain Glyco_hydro_16 PF00722.21 KND87092.1 - 4.1e-16 59.0 0.8 6.2e-16 58.4 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KND87092.1 - 9.9e-05 20.9 3.8 0.021 13.3 0.1 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) MFS_1 PF07690.16 KND87093.1 - 2.1e-25 89.4 28.9 7.9e-25 87.5 27.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Serglycin PF04360.12 KND87093.1 - 0.072 13.0 3.9 0.15 12.0 3.9 1.5 1 0 0 1 1 1 0 Serglycin Tetraspanin PF00335.20 KND87094.1 - 1.9e-05 24.5 0.3 3.1e-05 23.8 0.3 1.4 1 1 0 1 1 1 1 Tetraspanin family Asp PF00026.23 KND87096.1 - 3.5e-64 217.2 0.4 4.3e-64 216.9 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND87096.1 - 5.8e-07 29.9 3.0 0.02 15.2 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND87096.1 - 4.9e-05 23.9 3.0 0.042 14.5 0.9 3.1 2 1 0 2 2 2 2 Aspartyl protease Ldh_1_C PF02866.18 KND87097.1 - 5e-48 163.2 0.0 8.3e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KND87097.1 - 7.2e-44 149.3 0.1 3.2e-43 147.2 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KND87097.1 - 0.0076 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C2HC5 PF06221.13 KND87098.1 - 6.9e-22 77.2 6.1 1.1e-21 76.6 6.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAM176 PF14851.6 KND87098.1 - 0.15 11.7 0.6 0.38 10.4 0.6 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_A_exo1 PF01612.20 KND87099.1 - 0.0036 17.0 0.5 0.0067 16.2 0.5 1.4 1 0 0 1 1 1 1 3'-5' exonuclease RNase_T PF00929.24 KND87099.1 - 0.02 15.4 1.3 0.032 14.8 0.2 1.7 2 0 0 2 2 2 0 Exonuclease E1-E2_ATPase PF00122.20 KND87100.1 - 7e-16 58.3 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KND87100.1 - 4.1e-14 53.4 5.4 7.5e-09 36.2 2.1 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND87100.1 - 0.0034 17.2 0.1 0.082 12.6 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND87100.1 - 0.02 14.9 0.0 0.02 14.9 0.0 2.0 3 0 0 3 3 3 0 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KND87100.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF4059 PF13268.6 KND87100.1 - 0.47 10.9 5.5 11 6.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) SIR2 PF02146.17 KND87101.1 - 1.3e-32 113.2 0.1 1.7e-10 41.1 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Aminotran_5 PF00266.19 KND87102.1 - 2.7e-19 69.4 0.0 3.9e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TGS PF02824.21 KND87102.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 TGS domain Whi5 PF08528.11 KND87103.1 - 4e-10 39.1 0.0 7.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Whi5 like PALP PF00291.25 KND87104.1 - 1.5e-33 116.5 0.0 4.1e-33 115.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 KND87104.1 - 5.7e-06 26.8 0.0 0.00012 22.6 0.0 2.7 1 1 1 2 2 2 1 Rhodanese-like domain UPF1_Zn_bind PF09416.10 KND87105.1 - 5e-68 227.9 5.4 7.7e-68 227.2 2.1 2.4 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KND87105.1 - 8.9e-60 201.7 0.0 1.8e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND87105.1 - 1.8e-54 185.3 4.1 5.8e-31 108.2 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KND87105.1 - 5.4e-31 106.7 0.0 1.4e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KND87105.1 - 6.6e-14 52.1 1.4 2.3e-12 47.0 1.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND87105.1 - 1.2e-10 41.8 0.2 1.2e-10 41.8 0.2 2.0 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 KND87105.1 - 2.3e-06 27.7 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KND87105.1 - 2.2e-05 24.3 0.3 0.14 11.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KND87105.1 - 9.2e-05 22.4 0.1 0.0002 21.3 0.1 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 KND87105.1 - 0.00012 21.5 0.9 0.0028 16.9 0.1 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KND87105.1 - 0.00013 21.3 0.3 0.22 10.7 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 KND87105.1 - 0.00013 21.6 0.1 0.0033 17.0 0.1 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 KND87105.1 - 0.00033 20.1 0.1 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 KaiC DEAD PF00270.29 KND87105.1 - 0.0006 19.6 0.3 0.0012 18.7 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 KND87105.1 - 0.017 14.8 0.1 0.028 14.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 KND87105.1 - 0.023 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain T2SSE PF00437.20 KND87105.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KND87105.1 - 0.038 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_S13_N PF08069.12 KND87105.1 - 0.052 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.6 KND87105.1 - 0.089 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KND87105.1 - 0.11 11.8 1.1 2.9 7.1 0.0 2.6 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain Fungal_trans_2 PF11951.8 KND87106.1 - 2.7e-53 181.2 3.5 3.6e-53 180.8 3.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87106.1 - 1.2e-07 31.7 7.1 2.6e-07 30.6 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 KND87107.1 - 1.6e-44 152.3 0.0 2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AA_permease_2 PF13520.6 KND87108.1 - 1.2e-55 189.1 48.1 1.4e-55 188.9 48.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND87108.1 - 2.3e-30 105.6 40.5 3.1e-30 105.2 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 KND87108.1 - 5.5 6.3 5.9 2.5 7.4 2.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4257 PF14074.6 KND87108.1 - 9.8 6.5 10.1 33 4.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4257) Dicty_CAR PF05462.11 KND87109.1 - 4.9e-11 42.3 5.6 6.4e-11 41.9 5.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KND87109.1 - 3.3e-08 33.1 7.8 5.4e-08 32.4 7.8 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 KND87109.1 - 8.1e-07 28.4 6.6 0.00023 20.3 1.9 2.1 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Git3 PF11710.8 KND87109.1 - 0.035 13.9 11.2 0.2 11.4 11.3 2.0 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 GMC_oxred_N PF00732.19 KND87110.1 - 3.7e-58 197.2 0.0 5e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND87110.1 - 1e-28 100.7 0.0 1.6e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND87110.1 - 0.00026 20.2 0.4 0.035 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KND87110.1 - 0.0035 16.5 0.3 0.0058 15.7 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein MFS_1 PF07690.16 KND87111.1 - 1.7e-06 27.2 6.8 2.4e-06 26.7 6.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87111.1 - 0.00019 20.4 5.0 0.00024 20.1 5.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Ank_2 PF12796.7 KND87112.1 - 2.2e-48 162.7 0.1 2.2e-15 57.0 0.0 5.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND87112.1 - 4.6e-34 112.6 0.0 7.2e-06 26.0 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KND87112.1 - 9.4e-34 114.4 0.0 4.8e-06 26.8 0.0 7.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 KND87112.1 - 1.5e-31 108.3 0.1 9e-09 35.7 0.0 5.2 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND87112.1 - 1.5e-30 104.8 0.6 3.7e-07 30.3 0.0 5.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Sugar_tr PF00083.24 KND87113.1 - 1.4e-79 268.1 25.9 1.7e-79 267.8 25.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87113.1 - 1.2e-15 57.3 48.4 3.4e-15 55.8 28.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND87113.1 - 0.0032 16.1 23.5 0.0038 15.8 2.9 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.16 KND87114.1 - 2.4e-11 43.6 9.1 2.4e-11 43.6 9.1 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KND87114.1 - 3.4e-10 39.4 43.7 3.4e-10 39.4 43.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PrgI PF12666.7 KND87114.1 - 0.11 13.3 0.0 0.11 13.3 0.0 4.7 4 1 0 5 5 5 0 PrgI family protein Na_Ca_ex PF01699.24 KND87115.1 - 2.9e-34 118.2 39.0 1e-18 67.7 13.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.22 KND87116.1 - 2.8e-32 112.1 0.0 4.9e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KND87117.1 - 5.1e-43 147.5 0.0 6.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KND87118.1 - 7.7e-06 25.9 0.1 1.8e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND87118.1 - 1.4e-05 24.9 0.2 3.2e-05 23.8 0.2 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding PF00501.28 KND87119.1 - 8.7e-81 271.7 0.0 1.3e-80 271.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 KND87119.1 - 1.2e-70 238.0 0.0 3.5e-70 236.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KND87119.1 - 2.8e-59 201.0 0.0 5.5e-59 200.0 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KND87119.1 - 3.9e-53 180.6 0.9 6.7e-53 179.9 0.9 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KND87119.1 - 4.6e-46 157.8 0.0 9.3e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KND87119.1 - 6.6e-43 146.7 0.1 2e-42 145.1 0.1 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 KND87119.1 - 7.3e-32 109.9 0.0 2e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KND87119.1 - 4e-21 75.3 0.0 5.8e-20 71.5 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 KND87119.1 - 7.6e-19 68.3 0.0 1.9e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KND87119.1 - 2.7e-18 66.1 1.7 4.1e-10 39.9 0.1 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KND87119.1 - 5.3e-13 49.4 0.0 1.5e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KND87119.1 - 1.5e-12 48.1 0.0 4.5e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87119.1 - 1.5e-11 44.4 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KND87119.1 - 1.5e-10 41.0 0.0 4e-09 36.3 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KND87119.1 - 1.3e-09 38.6 0.1 4.4e-09 36.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KND87119.1 - 4.1e-09 37.3 2.6 1e-08 36.0 0.4 3.0 3 0 0 3 3 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 KND87119.1 - 3.7e-07 29.8 0.0 5.2e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KND87119.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KND87119.1 - 2.1e-05 24.0 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 KND87119.1 - 4.7e-05 22.8 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KND87119.1 - 0.0026 17.4 0.0 0.0078 15.8 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 KND87119.1 - 0.12 12.1 0.8 0.72 9.5 0.8 2.1 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis RrnaAD PF00398.20 KND87119.1 - 0.23 10.5 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase YscJ_FliF PF01514.17 KND87120.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family Fungal_trans PF04082.18 KND87121.1 - 1.5e-13 50.4 0.1 3.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87121.1 - 4e-08 33.2 12.1 8.9e-08 32.1 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KND87122.1 - 2.5e-09 37.1 0.0 5.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KND87122.1 - 5.2e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KND87122.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein p450 PF00067.22 KND87123.1 - 1.2e-58 199.0 0.0 1.5e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RFC1 PF08519.12 KND87123.1 - 0.12 12.6 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain GRAM PF02893.20 KND87124.1 - 8.9e-29 99.7 0.5 1.7e-16 60.1 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KND87124.1 - 3.6e-27 95.1 0.0 7.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 KND87124.1 - 9.3e-13 48.6 0.0 2.6e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 KND87124.1 - 2.1e-05 23.5 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 KND87124.1 - 2.3e-05 24.6 0.1 5.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KND87124.1 - 0.00017 22.0 0.9 0.0023 18.3 0.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain BtrH_N PF14399.6 KND87124.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal HOASN PF14515.6 KND87124.1 - 0.12 12.8 0.3 0.42 11.0 0.1 1.9 1 1 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Mso1_Sec1_bdg PF14475.6 KND87124.1 - 0.12 12.0 0.1 14 5.4 0.1 2.9 2 0 0 2 2 2 0 Sec1-binding region of Mso1 TAL_FSA PF00923.19 KND87125.1 - 1.5e-30 106.5 0.0 2.5e-30 105.8 0.0 1.4 2 0 0 2 2 2 1 Transaldolase/Fructose-6-phosphate aldolase Acetyltransf_1 PF00583.25 KND87126.1 - 8.7e-12 45.3 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND87126.1 - 9.5e-11 41.7 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND87126.1 - 5e-10 39.7 0.2 8.3e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KND87126.1 - 0.0043 17.2 0.0 0.0055 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND87126.1 - 0.0056 17.4 0.0 0.0074 17.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND87126.1 - 0.033 14.3 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND87126.1 - 0.034 14.1 0.0 0.062 13.3 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Na_trans_assoc PF06512.13 KND87127.1 - 0.22 11.8 2.3 0.35 11.1 0.9 1.9 2 0 0 2 2 2 0 Sodium ion transport-associated DndB PF14072.6 KND87128.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 DNA-sulfur modification-associated DUF3723 PF12520.8 KND87128.1 - 0.028 13.1 1.7 0.045 12.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Senescence_reg PF04520.13 KND87128.1 - 0.039 14.8 3.6 0.12 13.3 3.6 1.9 1 0 0 1 1 1 0 Senescence regulator FAD_binding_4 PF01565.23 KND87129.1 - 8.9e-23 80.6 2.7 1.9e-22 79.5 2.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND87129.1 - 4.6e-11 42.6 0.2 9e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KND87129.1 - 0.0053 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding PepSY_TM_like_2 PF16357.5 KND87130.1 - 0.79 9.7 7.7 3.7 7.5 0.8 2.3 2 0 0 2 2 2 0 Putative PepSY_TM-like Cu-oxidase_3 PF07732.15 KND87131.1 - 1e-39 135.2 0.9 1.3e-38 131.7 0.1 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND87131.1 - 3.4e-32 111.1 3.9 1.7e-31 108.8 0.5 2.6 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KND87131.1 - 6.2e-18 65.4 0.0 8.6e-16 58.4 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase EHN PF06441.12 KND87133.1 - 1.4e-37 128.4 0.4 1.8e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KND87133.1 - 7e-12 45.5 0.1 1.1e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND87133.1 - 0.026 15.1 9.2 0.013 16.1 5.6 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family APH PF01636.23 KND87134.1 - 1.5e-14 54.5 0.3 2e-14 54.1 0.3 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87134.1 - 0.0033 17.0 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase OPT PF03169.15 KND87135.1 - 2.1e-178 594.8 45.1 2.4e-178 594.6 45.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FATC PF02260.20 KND87135.1 - 0.058 13.2 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 FATC domain Na_Ca_ex PF01699.24 KND87136.1 - 1.5e-26 93.2 32.4 1e-14 54.8 18.2 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4365 PF14280.6 KND87136.1 - 0.23 11.4 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) UPF0444 PF15475.6 KND87136.1 - 1 9.7 4.7 2.7 8.3 4.7 1.6 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 Cation_ATPase_C PF00689.21 KND87137.1 - 1.4e-78 262.8 25.3 1.2e-43 149.0 10.6 4.8 5 0 0 5 5 5 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KND87137.1 - 1.9e-66 223.1 6.7 5.7e-36 123.7 0.0 4.9 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 KND87137.1 - 2.2e-42 145.7 2.2 1.4e-20 74.5 0.2 3.1 2 2 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND87137.1 - 4.8e-39 132.3 0.0 7.9e-22 77.2 0.0 2.9 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Na_Ca_ex PF01699.24 KND87137.1 - 1.4e-15 57.6 30.7 1.4e-09 38.1 12.6 5.7 7 0 0 7 7 7 2 Sodium/calcium exchanger protein Cation_ATPase_N PF00690.26 KND87137.1 - 4.3e-11 42.3 0.1 0.0014 18.3 0.0 3.9 3 0 0 3 3 3 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND87137.1 - 2.3e-07 30.8 3.7 0.0029 17.4 0.1 3.3 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND87137.1 - 8.3e-05 23.1 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3339 PF11820.8 KND87137.1 - 0.16 12.2 6.1 0.41 10.9 1.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3339) S_4TM PF18159.1 KND87137.1 - 6.7 5.9 7.0 1.6 8.0 2.1 2.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain Metallopep PF12044.8 KND87139.1 - 3.1e-94 316.0 0.0 3.9e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 KND87139.1 - 0.0036 17.8 0.8 0.0092 16.5 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KND87139.1 - 0.0043 17.2 0.2 0.0098 16.1 0.2 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 KND87139.1 - 0.19 10.6 0.1 0.36 9.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 Gly_transf_sug PF04488.15 KND87140.1 - 5.8e-07 30.1 0.1 1.1e-06 29.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif WSN PF02206.18 KND87143.1 - 0.0035 17.2 0.8 0.013 15.4 0.8 1.9 1 1 0 1 1 1 1 Domain of unknown function HNH_2 PF13391.6 KND87143.1 - 0.042 14.0 0.0 0.18 12.0 0.0 2.1 3 0 0 3 3 3 0 HNH endonuclease MFS_1 PF07690.16 KND87144.1 - 2.5e-13 49.7 54.4 1.8e-11 43.6 54.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CcmD PF04995.14 KND87144.1 - 0.029 14.4 1.1 0.15 12.2 1.1 2.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pox_A14 PF05767.12 KND87144.1 - 0.49 10.6 9.0 0.23 11.6 0.4 3.8 2 1 0 3 3 3 0 Poxvirus virion envelope protein A14 CFEM PF05730.11 KND87145.1 - 9.4e-08 32.0 5.4 1.5e-07 31.4 5.4 1.3 1 0 0 1 1 1 1 CFEM domain DUF4692 PF15763.5 KND87145.1 - 3.5 8.1 10.0 0.7 10.3 6.1 1.7 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) QWRF PF04484.12 KND87145.1 - 3.7 7.2 11.3 4.7 6.9 11.3 1.1 1 0 0 1 1 1 0 QWRF family SOG2 PF10428.9 KND87145.1 - 7.5 5.6 14.7 8.8 5.4 14.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_M28 PF04389.17 KND87148.1 - 1.7e-42 145.4 0.0 2.6e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KND87148.1 - 2.5e-09 37.0 0.9 8.9e-09 35.3 0.1 2.3 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.28 KND87148.1 - 2.9e-05 23.9 0.0 6.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Myco_arth_vir_N PF09610.10 KND87148.1 - 0.059 13.5 1.6 0.16 12.1 1.6 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) WD40 PF00400.32 KND87149.1 - 6.4e-09 36.3 4.6 1.9 9.5 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Cupin_2 PF07883.11 KND87150.1 - 0.065 13.0 1.7 7.5 6.4 0.0 3.3 3 0 0 3 3 3 0 Cupin domain PMI_typeI PF01238.21 KND87150.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Phosphomannose isomerase type I Pkinase PF00069.25 KND87151.1 - 7.2e-05 22.3 0.2 0.0002 20.8 0.2 1.7 1 1 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KND87151.1 - 0.0024 17.5 0.0 0.005 16.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KND87151.1 - 0.0025 17.2 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND87151.1 - 0.092 12.7 5.1 0.098 12.6 0.0 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.23 KND87151.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Fungal_trans PF04082.18 KND87152.1 - 2.7e-18 66.0 0.0 4.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87152.1 - 3.7e-08 33.4 13.9 3.7e-08 33.4 13.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4051 PF13260.6 KND87152.1 - 0.016 15.0 0.1 0.056 13.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) zf-P11 PF03854.14 KND87152.1 - 0.12 12.0 4.3 0.18 11.5 0.9 2.7 2 0 0 2 2 2 0 P-11 zinc finger ADH_N PF08240.12 KND87153.1 - 2.1e-28 98.4 0.7 4.4e-28 97.3 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND87153.1 - 8.4e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND87153.1 - 2.6e-06 27.1 0.0 4.5e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KND87153.1 - 3.7e-05 24.8 0.0 0.0002 22.4 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KND87153.1 - 0.00031 20.6 1.0 0.00053 19.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KND87153.1 - 0.0012 18.2 0.5 0.0019 17.5 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyoxalase_6 PF18029.1 KND87153.1 - 0.085 13.7 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain NEMO PF11577.8 KND87154.1 - 5 7.2 6.8 1.7 8.7 0.2 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO MFS_1 PF07690.16 KND87155.1 - 1.6e-21 76.7 36.8 1.9e-19 69.8 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.22 KND87156.1 - 3.7e-116 388.4 0.0 4.3e-65 220.0 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KND87157.1 - 1.3e-23 83.4 2.3 2.1e-23 82.7 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87157.1 - 3.1e-06 27.2 7.9 3.1e-06 27.2 7.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_transf_sug PF04488.15 KND87159.1 - 7.6e-07 29.7 0.0 2.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif HlyC PF02794.16 KND87159.1 - 0.14 12.1 0.8 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 RTX toxin acyltransferase family F-box PF00646.33 KND87160.1 - 0.022 14.7 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain Gly_transf_sug PF04488.15 KND87162.1 - 3.5e-11 43.6 0.0 8.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PIG-L PF02585.17 KND87163.1 - 2.9e-20 73.2 0.0 4.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Saf_2TM PF18303.1 KND87163.1 - 0.043 13.4 0.1 0.068 12.8 0.1 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain adh_short PF00106.25 KND87164.1 - 8e-13 48.3 3.2 2.6e-12 46.6 1.9 2.0 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND87164.1 - 7.8e-12 45.2 0.4 1.2e-11 44.6 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Lactamase_B_2 PF12706.7 KND87165.1 - 1.5e-13 50.8 0.0 2.9e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KND87165.1 - 3.8e-12 46.4 0.0 5.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Phosphoesterase PF04185.14 KND87166.1 - 2.2e-77 260.7 0.2 3.4e-77 260.0 0.2 1.2 1 0 0 1 1 1 1 Phosphoesterase family CbtA PF09490.10 KND87167.1 - 0.78 9.5 3.0 0.93 9.2 3.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Methyltransf_2 PF00891.18 KND87168.1 - 1e-10 41.3 0.0 1.1e-09 37.9 0.0 2.1 1 1 0 2 2 2 1 O-methyltransferase domain FAD_binding_2 PF00890.24 KND87170.1 - 3.2e-66 224.2 0.1 3.9e-66 223.8 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KND87171.1 - 5.4e-19 68.6 0.0 6.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND87171.1 - 4.9e-06 26.7 0.1 8.5e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KND87171.1 - 0.00019 20.8 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KND87171.1 - 0.00043 19.5 0.0 0.00047 19.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 KND87171.1 - 0.0013 18.1 0.1 0.0015 17.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KND87171.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND87171.1 - 0.0094 15.6 0.0 0.0094 15.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND87171.1 - 0.011 14.4 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KND87171.1 - 0.02 14.2 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KND87171.1 - 0.08 12.3 0.0 0.083 12.2 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 KND87173.1 - 6.8e-34 117.3 59.8 1.1e-31 110.1 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KND87173.1 - 0.018 13.4 3.1 0.52 8.5 1.0 3.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CLP1_P PF16575.5 KND87174.1 - 2.2e-35 122.2 0.0 3.3e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KND87174.1 - 1.9e-26 92.1 0.0 3.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KND87174.1 - 1.4e-25 90.0 0.0 1.2e-24 87.0 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 KTI12 PF08433.10 KND87174.1 - 0.00015 21.3 0.0 0.0052 16.3 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KND87174.1 - 0.00024 21.5 0.0 0.00059 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 KND87174.1 - 0.00026 21.0 0.2 0.0038 17.3 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KND87174.1 - 0.00046 20.3 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 KND87174.1 - 0.00085 19.2 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KND87174.1 - 0.0091 16.5 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND87174.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KND87174.1 - 0.023 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 KND87174.1 - 0.05 14.0 0.1 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KND87174.1 - 0.14 11.8 0.0 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KND87174.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KND87174.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KND87174.1 - 0.17 11.6 0.0 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 KND87174.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FeoB_N PF02421.18 KND87174.1 - 0.18 11.3 0.1 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 KND87174.1 - 0.2 11.0 0.0 0.47 9.8 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 KND87174.1 - 0.21 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 KND87175.1 - 2.1e-35 121.9 20.8 1.7e-30 105.8 0.3 4.0 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND87175.1 - 1.6e-29 103.0 1.2 1.6e-29 103.0 1.2 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KND87175.1 - 3.7e-22 79.7 0.2 8.2e-18 65.5 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND87175.1 - 2.6e-17 62.2 0.0 5.8e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KND87175.1 - 5.4e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KND87175.1 - 3.9e-06 26.8 0.2 0.00019 21.2 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KND87175.1 - 0.037 13.9 1.1 0.076 12.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) p6 PF17548.2 KND87175.1 - 0.14 12.1 0.3 0.37 10.8 0.3 1.7 1 0 0 1 1 1 0 Histone-like Protein p6 IncE PF17627.2 KND87175.1 - 5.6 7.0 7.9 0.22 11.5 1.0 2.1 2 0 0 2 2 2 0 Inclusion membrane protein E Zip PF02535.22 KND87176.1 - 3.4e-56 190.9 3.0 4e-56 190.7 3.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Beta-lactamase PF00144.24 KND87177.1 - 3e-42 145.0 0.4 3.8e-42 144.7 0.4 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KND87177.1 - 2.5e-07 31.1 0.1 5.9e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) OCRE PF17780.1 KND87177.1 - 0.14 12.2 1.3 16 5.7 0.2 2.4 2 0 0 2 2 2 0 OCRE domain APH PF01636.23 KND87179.1 - 2e-16 60.7 0.0 6.3e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND87179.1 - 8.3e-05 22.3 0.1 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 KND87179.1 - 0.0013 18.0 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.11 KND87179.1 - 0.0041 16.0 0.0 0.044 12.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KND87179.1 - 0.0057 16.3 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND87180.1 - 0.063 12.6 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DLH PF01738.18 KND87182.1 - 4.2e-06 26.5 0.0 0.0051 16.4 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KND87182.1 - 2e-05 25.3 0.4 0.00031 21.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.11 KND87182.1 - 2.5e-05 23.2 0.0 4.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 KND87182.1 - 0.00046 20.2 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KND87182.1 - 0.00048 19.7 0.1 0.012 15.1 0.0 2.1 1 1 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KND87182.1 - 0.003 16.3 0.1 0.025 13.2 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KND87182.1 - 0.003 17.2 0.1 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KND87182.1 - 0.051 13.7 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S15 PF02129.18 KND87182.1 - 0.089 12.4 0.1 0.55 9.8 0.1 2.2 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Zn_clus PF00172.18 KND87183.1 - 4.9e-08 33.0 11.1 7e-08 32.5 11.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND87183.1 - 0.0018 17.1 0.6 0.0043 15.9 0.6 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain GATase PF00117.28 KND87184.1 - 1.3e-10 41.3 0.0 1.9e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KND87184.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Git3 PF11710.8 KND87185.1 - 9e-45 152.9 13.6 3.4e-44 151.1 13.6 1.8 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 KND87185.1 - 8.8e-17 61.0 4.2 1.2e-16 60.5 0.2 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term p450 PF00067.22 KND87186.1 - 4.3e-23 81.8 0.0 2.7e-16 59.4 0.0 3.7 2 1 1 3 3 3 3 Cytochrome P450 ketoacyl-synt PF00109.26 KND87187.1 - 1.1e-71 241.4 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND87187.1 - 1.3e-25 89.7 0.0 3.1e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KND87187.1 - 9.2e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KND87187.1 - 0.033 14.0 0.7 0.073 12.9 0.1 1.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2236 PF09995.9 KND87188.1 - 2.7e-25 89.9 0.1 3.4e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Glyco_hydro_61 PF03443.14 KND87190.1 - 0.0018 18.3 0.2 0.0041 17.1 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 BNR PF02012.20 KND87190.1 - 0.021 14.7 0.1 0.15 12.1 0.1 2.6 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo-co_dimer PF03404.16 KND87190.1 - 0.054 13.5 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain peroxidase PF00141.23 KND87191.1 - 6.4e-84 281.2 0.1 1.5e-41 142.6 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Glyco_hydro_2_N PF02837.18 KND87192.1 - 4.9e-14 52.6 0.4 1.4e-13 51.1 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KND87192.1 - 3.5e-09 37.3 0.0 1.2e-08 35.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KND87192.1 - 6.3e-08 32.1 0.0 7e-07 28.6 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 KND87192.1 - 0.087 13.4 0.7 0.26 11.9 0.3 2.0 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Pkinase PF00069.25 KND87193.1 - 0.00027 20.4 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND87193.1 - 0.0041 17.1 0.0 0.0041 17.1 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87193.1 - 0.019 14.6 0.0 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase GARP PF16731.5 KND87193.1 - 0.12 12.1 22.0 0.23 11.1 22.0 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma eIF3_subunit PF08597.10 KND87193.1 - 0.95 9.3 12.4 2 8.2 12.4 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF874 PF05917.11 KND87193.1 - 4.1 6.4 6.5 6.4 5.7 6.5 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF2828 PF11443.8 KND87193.1 - 6.9 4.6 8.5 11 3.9 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NACHT PF05729.12 KND87194.1 - 4.3e-07 30.0 0.1 1.1e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND87194.1 - 8e-07 29.6 0.0 2.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KND87194.1 - 0.0027 18.3 0.0 0.0071 17.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KND87194.1 - 0.0034 17.7 0.0 0.0086 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 KND87194.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ABC_tran PF00005.27 KND87194.1 - 0.0069 16.9 0.0 0.055 14.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 KND87194.1 - 0.0072 16.7 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KND87194.1 - 0.013 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KND87194.1 - 0.017 15.6 0.0 0.67 10.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 KND87194.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_29 PF13555.6 KND87194.1 - 0.026 14.3 0.0 0.093 12.5 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KND87194.1 - 0.031 14.8 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KND87194.1 - 0.037 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KND87194.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Hydrolase_4 PF12146.8 KND87194.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NB-ARC PF00931.22 KND87194.1 - 0.17 11.0 0.0 0.58 9.3 0.0 1.9 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KND87194.1 - 0.19 12.1 0.0 0.54 10.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 KND87194.1 - 0.21 11.2 0.0 0.48 10.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PNP_UDP_1 PF01048.20 KND87195.1 - 0.00022 20.6 0.1 0.0012 18.1 0.0 1.8 1 1 1 2 2 2 1 Phosphorylase superfamily DUF3046 PF11248.8 KND87196.1 - 0.051 13.9 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Spike_torovirin PF17072.5 KND87196.1 - 0.16 9.1 0.0 0.19 8.9 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Cerato-platanin PF07249.12 KND87197.1 - 7.7e-05 22.8 0.2 0.00014 22.0 0.2 1.4 1 0 0 1 1 1 1 Cerato-platanin CDC37_N PF03234.14 KND87201.1 - 2.3e-45 154.7 1.9 2.3e-45 154.7 1.9 3.0 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KND87201.1 - 6e-32 110.0 0.5 1.8e-31 108.5 0.5 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KND87201.1 - 3e-27 94.7 1.4 3e-27 94.7 1.4 2.8 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF3573 PF12097.8 KND87201.1 - 0.084 11.7 0.5 0.13 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LMBR1 PF04791.16 KND87201.1 - 0.59 9.0 2.1 0.95 8.3 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ank_2 PF12796.7 KND87203.1 - 9.6e-93 304.9 5.9 5.5e-17 62.1 0.0 8.1 4 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND87203.1 - 5.9e-65 207.5 1.1 0.0001 22.4 0.0 15.4 15 0 0 15 15 15 12 Ankyrin repeat Ank PF00023.30 KND87203.1 - 1.7e-60 199.0 11.6 0.0001 22.5 0.0 15.3 14 1 1 15 15 15 12 Ankyrin repeat Ank_4 PF13637.6 KND87203.1 - 8.2e-60 198.5 2.0 6.9e-10 39.3 0.0 11.2 5 3 8 14 14 14 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND87203.1 - 1.3e-59 197.4 12.3 2.4e-09 37.3 0.0 13.2 4 3 9 14 14 14 13 Ankyrin repeats (many copies) WW PF00397.26 KND87203.1 - 5.6e-17 61.5 2.5 7.1e-08 32.4 0.6 2.4 2 0 0 2 2 2 2 WW domain NACHT PF05729.12 KND87203.1 - 2.2e-08 34.2 0.2 1.4e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KND87203.1 - 0.00043 20.6 0.1 0.0026 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helo_like_N PF17111.5 KND87203.1 - 0.00058 19.3 2.6 0.00079 18.9 0.6 2.3 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins NB-ARC PF00931.22 KND87203.1 - 0.022 13.9 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain GATase_7 PF13537.6 KND87203.1 - 0.025 14.5 0.0 48 3.9 0.0 5.5 5 2 1 7 7 7 0 Glutamine amidotransferase domain Transcrip_act PF04949.13 KND87203.1 - 0.043 13.7 0.1 0.69 9.8 0.1 2.4 2 0 0 2 2 2 0 Transcriptional activator ATG16 PF08614.11 KND87203.1 - 0.098 12.9 4.9 0.99 9.6 0.6 2.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SesA PF17107.5 KND87203.1 - 0.29 11.3 1.9 1.5 9.1 0.2 3.1 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Prefoldin PF02996.17 KND87203.1 - 0.55 10.1 2.9 13 5.7 0.0 3.2 3 0 0 3 3 3 0 Prefoldin subunit Rx_N PF18052.1 KND87203.1 - 2.2 8.6 5.3 2.2 8.6 0.3 2.9 3 0 0 3 3 2 0 Rx N-terminal domain VWA_3_C PF18571.1 KND87203.1 - 4.8 7.1 13.0 4.2 7.3 0.2 6.0 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Ank_5 PF13857.6 KND87204.1 - 1.1e-17 63.8 1.9 2.7e-06 27.5 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87204.1 - 8.4e-17 61.5 0.8 1.2e-06 29.0 0.0 5.1 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87204.1 - 1.8e-11 44.3 0.6 0.00044 20.7 0.0 5.8 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87204.1 - 5.7e-09 35.5 0.2 0.32 11.7 0.1 8.0 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 KND87204.1 - 1.2e-08 34.9 5.0 0.33 11.5 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeat SNF2_N PF00176.23 KND87205.1 - 4.7e-25 88.0 1.6 9.5e-24 83.7 0.0 2.9 1 1 2 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND87205.1 - 2e-11 44.2 0.0 5.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND87205.1 - 1.2e-09 38.4 0.0 3.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KND87205.1 - 3.9e-05 23.0 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_UBOX PF13445.6 KND87205.1 - 2.7 8.1 7.3 8.9 6.4 7.3 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF2058 PF09831.9 KND87205.1 - 4.8 7.3 11.2 2.2 8.4 5.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) NAM-associated PF14303.6 KND87205.1 - 8.6 7.0 18.9 0.5 11.1 12.9 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Phage_holin_2_4 PF16082.5 KND87206.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like HET PF06985.11 KND87207.1 - 2.7e-24 86.2 0.1 4.5e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IPK PF03770.16 KND87208.1 - 5.2e-50 170.1 0.0 6.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arc_PepC PF06819.11 KND87208.1 - 0.13 12.4 0.1 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Arb1 PF09692.10 KND87209.1 - 1.6e-122 409.6 0.0 1.9e-122 409.3 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Rrn6 PF10214.9 KND87209.1 - 0.56 8.6 2.3 0.77 8.2 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pmp3 PF01679.17 KND87210.1 - 6.1e-19 68.0 11.5 8.2e-19 67.6 11.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator HA2 PF04408.23 KND87211.1 - 5.4e-23 81.3 0.1 5.4e-23 81.3 0.1 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KND87211.1 - 1e-20 73.8 0.0 2.3e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 KND87211.1 - 2e-11 44.0 0.8 4.4e-11 43.0 0.8 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 KND87211.1 - 9.7e-09 35.6 0.0 2.8e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND87211.1 - 4.3e-06 26.6 0.5 1.5e-05 24.8 0.5 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND87211.1 - 6.2e-06 26.5 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KND87211.1 - 0.0001 21.4 0.3 0.00053 19.1 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 KND87211.1 - 0.0018 18.0 0.1 0.0068 16.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KND87211.1 - 0.0046 17.3 0.1 0.01 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KND87211.1 - 0.017 15.2 0.8 0.52 10.3 0.3 2.7 2 1 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KND87211.1 - 0.026 13.7 0.5 0.059 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Microtub_bd PF16796.5 KND87211.1 - 0.058 13.3 0.3 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Microtubule binding PhoH PF02562.16 KND87211.1 - 0.069 12.6 0.3 0.22 10.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 KND87211.1 - 0.34 11.4 3.3 0.56 10.7 0.1 2.9 3 1 1 4 4 3 0 ABC transporter CVNH PF08881.10 KND87212.1 - 2.1e-22 79.7 0.0 2.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Ferric_reduct PF01794.19 KND87213.1 - 6.4e-23 81.2 14.5 1.6e-22 79.9 14.5 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND87213.1 - 1.3e-08 34.9 0.0 3.8e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KND87213.1 - 1.3e-06 28.6 0.0 0.0025 17.9 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain SNF2_N PF00176.23 KND87214.1 - 3.3e-66 223.4 0.4 7e-66 222.3 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND87214.1 - 2.6e-22 79.3 0.0 5.3e-21 75.0 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND87214.1 - 6.7e-10 39.2 0.0 2.1e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND87214.1 - 0.00013 21.8 0.0 0.0003 20.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 KND87214.1 - 0.00029 20.1 0.0 0.00029 20.1 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 KND87214.1 - 0.002 17.8 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 SWI2/SNF2 ATPase TniB PF05621.11 KND87214.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KND87214.1 - 0.047 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pinin_SDK_memA PF04696.13 KND87214.1 - 0.057 13.5 11.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Luteo_P1-P2 PF08467.10 KND87214.1 - 0.22 10.8 2.7 0.45 9.7 2.7 1.4 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Ank_2 PF12796.7 KND87215.1 - 2.7e-38 130.4 23.6 3.2e-08 34.0 0.0 14.3 9 5 6 15 15 15 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87215.1 - 2.1e-20 72.8 19.5 0.0056 17.2 0.0 15.6 17 2 1 18 18 18 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87215.1 - 5.4e-19 66.3 12.1 0.067 13.8 0.0 17.3 19 0 0 19 19 19 2 Ankyrin repeat Ank PF00023.30 KND87215.1 - 2.5e-15 56.1 30.9 0.077 13.5 0.0 15.8 16 2 0 16 16 16 4 Ankyrin repeat Ank_5 PF13857.6 KND87215.1 - 4e-11 42.9 7.0 0.0001 22.5 0.0 11.0 10 3 3 13 13 13 1 Ankyrin repeats (many copies) MTBP_C PF14920.6 KND87215.1 - 2 8.1 10.8 0.95 9.2 8.2 1.7 2 0 0 2 2 2 0 MDM2-binding RsfS PF02410.15 KND87216.1 - 1.3e-10 41.5 0.0 1e-09 38.7 0.0 2.3 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation RNA_pol PF00940.19 KND87217.1 - 1.1e-184 614.1 0.0 1.8e-184 613.4 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KND87217.1 - 8.8e-98 327.8 2.9 1.6e-97 326.9 2.9 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DHHA2 PF02833.14 KND87219.1 - 2.3e-34 118.7 0.0 3.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KND87219.1 - 6.6e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 DHH family p450 PF00067.22 KND87224.1 - 6.1e-28 97.8 0.0 1.1e-19 70.5 0.0 2.2 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KND87225.1 - 4.4e-08 32.3 0.0 4.8e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 KND87226.1 - 2.5e-53 181.0 0.0 3.1e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87226.1 - 2.5e-43 147.8 0.0 3.1e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND87226.1 - 4.8e-06 26.6 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DFP PF04127.15 KND87226.1 - 0.11 12.3 2.1 0.3 10.9 2.1 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MatE PF01554.18 KND87227.1 - 3.4e-54 182.8 20.1 4.6e-27 94.7 8.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KND87227.1 - 0.00012 22.2 10.8 0.00012 22.2 10.8 4.3 3 2 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KND87228.1 - 1.6e-87 293.6 0.0 2e-87 293.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KND87228.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Abhydrolase_1 PF00561.20 KND87231.1 - 0.00049 19.8 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND87231.1 - 0.0011 19.6 1.6 0.0013 19.3 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 KND87231.1 - 0.0021 17.9 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 KND87231.1 - 0.13 11.5 0.0 0.63 9.3 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Endosulfine PF04667.17 KND87232.1 - 3.5e-17 62.3 0.0 6.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Med3 PF11593.8 KND87233.1 - 7.2 5.7 10.9 15 4.7 10.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 KND87235.1 - 2.8e-29 102.3 0.0 2.5e-14 53.3 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND87235.1 - 1.7e-13 50.5 0.0 1.8e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 KND87235.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND87235.1 - 0.0063 16.5 0.3 0.021 14.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family BTRD1 PF17660.1 KND87235.1 - 0.12 12.2 0.1 0.34 10.7 0.1 1.8 1 1 0 1 1 1 0 Bacterial tandem repeat domain 1 Sec7 PF01369.20 KND87235.1 - 0.22 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Sec7 domain HHV-5_US34A PF17087.5 KND87235.1 - 0.41 10.8 2.4 8.8 6.6 0.4 2.4 2 0 0 2 2 2 0 Herpesvirus US34A protein family Pkinase PF00069.25 KND87238.1 - 4.7e-44 150.7 0.0 6.2e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87238.1 - 5.2e-17 62.0 0.0 7.8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KND87238.1 - 6.2e-11 42.7 0.0 3.1e-05 24.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87238.1 - 6.2e-10 39.4 0.3 8.5e-06 26.2 0.0 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87238.1 - 6.4e-07 29.2 0.1 0.61 10.8 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 KND87238.1 - 0.0053 17.1 0.8 0.38 11.1 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) tRNA-synt_1g PF09334.11 KND87239.1 - 8.1e-142 472.6 0.0 1.1e-141 472.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KND87239.1 - 9.6e-05 20.8 0.3 0.0026 16.1 0.0 2.9 2 2 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND87239.1 - 0.0016 18.4 0.2 0.0041 17.1 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA TipAS PF07739.13 KND87239.1 - 0.86 10.2 4.8 9.5 6.8 2.3 2.8 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain SUZ PF12752.7 KND87240.1 - 0.26 12.1 6.5 0.76 10.6 6.5 1.8 1 0 0 1 1 1 0 SUZ domain Keratin_matx PF04579.12 KND87241.1 - 0.044 14.1 0.6 0.2 12.0 0.2 2.1 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein Rrp15p PF07890.12 KND87242.1 - 0.38 11.1 2.7 0.84 10.0 0.0 2.1 2 1 0 2 2 2 0 Rrp15p Epimerase PF01370.21 KND87243.1 - 3.7e-05 23.3 0.0 3.8e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KND87243.1 - 4.2e-05 22.8 0.0 4.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KND87243.1 - 0.0014 17.7 0.0 0.0014 17.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KND87243.1 - 0.0029 17.5 0.0 0.0031 17.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KND87243.1 - 0.0057 16.8 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 KND87243.1 - 0.012 14.7 0.0 0.013 14.6 0.0 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KND87243.1 - 0.017 15.4 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KND87243.1 - 0.023 14.8 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Stealth_CR2 PF11380.8 KND87243.1 - 0.025 14.7 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 NmrA PF05368.13 KND87243.1 - 0.07 12.7 0.0 0.073 12.6 0.0 1.0 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 KND87243.1 - 0.072 12.2 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KND87243.1 - 0.2 11.0 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FMO-like PF00743.19 KND87244.1 - 1.3e-58 198.8 0.0 8.4e-56 189.5 0.0 3.1 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND87244.1 - 4.6e-17 62.2 0.0 2.7e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND87244.1 - 5.8e-16 58.6 0.0 1.1e-13 51.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND87244.1 - 8.4e-08 31.7 0.1 8.1e-06 25.2 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KND87244.1 - 4.9e-05 23.4 0.4 0.32 11.0 0.1 3.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 KND87244.1 - 8.4e-05 23.0 0.1 0.0072 16.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND87244.1 - 0.00027 21.1 0.1 0.00099 19.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KND87244.1 - 0.0056 16.0 0.1 2.2 7.5 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase IlvN PF07991.12 KND87244.1 - 0.019 14.5 0.0 0.078 12.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KND87244.1 - 0.1 12.7 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_72 PF03198.14 KND87245.1 - 5.6e-125 416.8 5.3 7.6e-125 416.3 5.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase PAP2 PF01569.21 KND87245.1 - 2.3e-22 79.2 7.5 5.6e-22 78.0 7.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily X8 PF07983.13 KND87245.1 - 4.2e-20 72.2 7.9 1.1e-19 70.8 7.9 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 KND87245.1 - 3.8e-05 22.9 0.6 0.00012 21.3 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PAP2_3 PF14378.6 KND87245.1 - 0.057 13.1 7.9 0.13 11.9 7.9 1.6 1 0 0 1 1 1 0 PAP2 superfamily Mx_ML PF17536.2 KND87245.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Matrix and Matrix long proteins N-terminal Pkinase PF00069.25 KND87246.1 - 1.8e-06 27.6 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND87246.1 - 0.01 15.7 0.2 0.05 13.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family HSP70 PF00012.20 KND87248.1 - 1.7e-78 264.3 0.6 2.8e-78 263.6 0.6 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND87248.1 - 6e-08 31.9 0.1 1.2e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 KND87248.1 - 1.1e-05 25.3 0.5 2.6e-05 24.0 0.5 1.6 1 0 0 1 1 1 1 Periplasmic binding protein BRAP2 PF07576.12 KND87248.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 Rrp40_N PF18311.1 KND87249.1 - 4.9e-15 55.2 0.2 1.9e-14 53.3 0.2 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 KND87249.1 - 9.2e-15 54.7 0.0 2.6e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 KH domain NB-ARC PF00931.22 KND87250.1 - 0.0026 17.0 0.1 0.0041 16.3 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KND87250.1 - 0.038 13.9 0.1 0.49 10.3 0.0 2.2 2 1 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.14 KND87250.1 - 0.2 10.9 0.0 0.92 8.7 0.0 1.7 1 1 0 2 2 2 0 KAP family P-loop domain AF-4 PF05110.13 KND87252.1 - 0.026 12.6 2.6 0.03 12.4 2.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cytochrom_B558a PF05038.13 KND87252.1 - 0.3 10.6 1.4 0.44 10.1 1.4 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Pkinase PF00069.25 KND87254.1 - 2e-20 73.3 0.0 4.6e-17 62.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND87254.1 - 5.1e-05 22.7 0.0 0.00024 20.5 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Ank_2 PF12796.7 KND87255.1 - 5e-27 94.3 3.3 8.9e-15 55.1 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87255.1 - 4.3e-18 65.4 0.0 4.3e-05 24.0 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) NACHT PF05729.12 KND87255.1 - 6.2e-10 39.2 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 KND87255.1 - 1.1e-09 37.6 0.0 1.1 10.0 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KND87255.1 - 2.7e-09 37.0 0.1 0.022 15.2 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KND87255.1 - 1.1e-08 35.2 0.0 0.0072 16.6 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 KND87255.1 - 4.1e-05 24.0 0.9 0.00018 21.9 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND87255.1 - 0.00034 20.9 0.0 0.0012 19.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KND87255.1 - 0.03 14.7 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KND87255.1 - 0.053 12.7 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KND87255.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HTH_40 PF14493.6 KND87255.1 - 0.08 13.4 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain ATPase_2 PF01637.18 KND87255.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea HTH_20 PF12840.7 KND87255.1 - 0.17 12.0 1.4 2.1 8.5 0.1 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain GST_C_3 PF14497.6 KND87256.1 - 6.5e-05 23.1 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND87256.1 - 7.4e-05 22.9 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND87256.1 - 0.0016 18.4 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KND87256.1 - 0.0061 17.1 0.0 0.0079 16.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND87256.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NT-C2 PF10358.9 KND87257.1 - 4.5e-22 78.3 0.0 2.3e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ABC_tran PF00005.27 KND87258.1 - 2.5e-45 154.3 0.0 5.5e-22 78.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KND87258.1 - 4.1e-20 71.6 1.8 4.1e-20 71.6 1.8 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KND87258.1 - 3.3e-17 63.2 0.3 0.0003 20.7 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND87258.1 - 4.1e-11 42.7 0.4 0.031 13.7 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND87258.1 - 2.5e-08 33.5 0.2 0.0025 17.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KND87258.1 - 2.9e-08 34.5 2.6 0.039 14.5 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KND87258.1 - 2.4e-06 27.5 0.0 0.051 13.3 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND87258.1 - 1.2e-05 25.3 0.1 0.0092 15.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KND87258.1 - 1.3e-05 25.7 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 KND87258.1 - 3.3e-05 23.9 0.0 0.024 14.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KND87258.1 - 4.3e-05 24.1 0.0 0.17 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KND87258.1 - 5.6e-05 23.6 0.0 0.47 10.9 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND87258.1 - 7.4e-05 23.0 0.0 0.097 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KND87258.1 - 0.00038 20.4 0.2 1 9.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KND87258.1 - 0.0004 20.7 0.0 1.9 8.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 KND87258.1 - 0.00045 20.5 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND87258.1 - 0.0011 19.0 0.2 1.2 9.1 0.2 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 KND87258.1 - 0.0017 18.0 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KND87258.1 - 0.0019 18.2 0.0 2.4 8.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 KND87258.1 - 0.0046 17.1 0.3 0.69 10.1 0.1 3.2 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 KND87258.1 - 0.0048 17.0 0.0 3.7 7.6 0.0 3.1 3 0 0 3 3 3 1 Dynamin family Roc PF08477.13 KND87258.1 - 0.0054 17.0 0.1 3.2 8.0 0.1 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KND87258.1 - 0.0058 16.4 2.6 2 8.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 KND87258.1 - 0.0071 15.9 0.0 0.55 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KND87258.1 - 0.0073 15.5 0.0 5.1 6.2 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 KND87258.1 - 0.0074 16.7 0.0 2.1 8.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND87258.1 - 0.016 14.9 1.5 1.9 8.2 0.1 3.3 3 1 0 3 3 2 0 AAA domain DUF2813 PF11398.8 KND87258.1 - 0.023 14.0 0.5 3.5 6.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 KND87258.1 - 0.036 13.6 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 KND87258.1 - 0.039 13.9 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase DAP3 PF10236.9 KND87258.1 - 0.076 12.2 0.1 7.1 5.7 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 KND87258.1 - 0.093 11.8 0.1 10 5.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Phage_tail_2 PF06199.11 KND87258.1 - 0.094 12.8 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 Phage tail tube protein FeoB_N PF02421.18 KND87258.1 - 0.13 11.8 0.4 9 5.8 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B SbcCD_C PF13558.6 KND87258.1 - 0.24 11.6 1.0 14 6.0 0.1 3.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit UCR_14kD PF02271.16 KND87260.1 - 0.068 13.2 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Integrase_H2C2 PF17921.1 KND87260.1 - 0.14 12.3 0.2 0.87 9.7 0.1 2.2 2 0 0 2 2 2 0 Integrase zinc binding domain APH PF01636.23 KND87262.1 - 1.1e-10 41.9 0.7 1.6e-10 41.4 0.7 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acetyltransf_1 PF00583.25 KND87265.1 - 5e-13 49.3 0.0 1.8e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND87265.1 - 2.4e-12 47.1 0.1 1.4e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND87265.1 - 2.4e-12 46.9 0.0 4.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND87265.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND87265.1 - 1.2e-05 25.3 0.0 9.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KND87265.1 - 0.00019 21.5 0.0 0.00098 19.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND87265.1 - 0.1 13.3 0.0 2.5 8.8 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain TrkH PF02386.16 KND87266.1 - 2.8e-100 336.1 3.8 1.3e-97 327.4 0.2 2.1 2 0 0 2 2 2 2 Cation transport protein SNF2_N PF00176.23 KND87267.1 - 3e-64 216.9 0.8 6.6e-64 215.8 0.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KND87267.1 - 1.3e-47 161.6 16.1 1.3e-47 161.6 16.1 5.2 4 2 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 KND87267.1 - 1.1e-19 70.8 0.0 3.1e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND87267.1 - 1.2e-07 31.9 0.2 6.1e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KND87267.1 - 0.0041 16.3 0.0 0.046 12.9 0.0 2.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 YflT PF11181.8 KND87267.1 - 2.3 8.8 5.5 1.1 9.8 1.3 2.9 2 0 0 2 2 2 0 Heat induced stress protein YflT APH PF01636.23 KND87268.1 - 2.6e-05 24.3 0.2 4.8e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family HNH_2 PF13391.6 KND87269.1 - 1.2e-17 63.8 0.0 2.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF3435 PF11917.8 KND87270.1 - 1.9e-27 96.3 0.6 3.8e-26 92.0 0.6 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) SOGA PF11365.8 KND87270.1 - 0.051 14.7 0.4 0.12 13.6 0.4 1.5 1 0 0 1 1 1 0 Protein SOGA fn3_2 PF16893.5 KND87271.1 - 7.7e-37 125.3 0.0 1.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KND87271.1 - 9.6e-23 79.9 0.8 1.6e-22 79.2 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KND87271.1 - 4.3e-12 45.8 0.1 8.1e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KND87271.1 - 8.3e-11 42.1 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND87271.1 - 1.2e-05 25.6 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 KND87271.1 - 0.00015 21.9 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KND87271.1 - 0.006 16.9 0.0 0.017 15.5 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain adh_short PF00106.25 KND87272.1 - 0.02 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase SEN1_N PF12726.7 KND87274.1 - 3e-200 667.2 4.4 3.7e-200 666.9 4.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KND87274.1 - 4.4e-71 239.7 0.2 4.4e-71 239.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KND87274.1 - 1.5e-61 207.5 0.0 2.6e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND87274.1 - 3.4e-08 33.9 0.1 1.1e-07 32.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND87274.1 - 3.8e-07 30.0 3.1 0.00033 20.4 0.6 2.9 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.21 KND87274.1 - 6.3e-05 22.6 0.0 0.023 14.2 0.1 2.8 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KND87274.1 - 0.00022 21.1 0.2 0.24 11.1 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KND87274.1 - 0.037 14.3 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF244 PF03112.14 KND87274.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DNA_methylase PF00145.17 KND87275.1 - 1.4e-40 139.6 0.0 6.2e-28 98.1 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase AsnC_trans_reg2 PF17805.1 KND87275.1 - 0.048 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-like ligand binding domain Cons_hypoth95 PF03602.15 KND87275.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_12 PF13087.6 KND87276.1 - 8e-23 81.1 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND87276.1 - 6.8e-11 42.4 0.0 3.2e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KND87276.1 - 2e-08 33.9 0.1 4.5e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KND87276.1 - 0.00048 19.9 0.0 0.041 13.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Get5_bdg PF16843.5 KND87276.1 - 0.0083 15.6 0.1 0.62 9.6 0.1 2.4 2 0 0 2 2 2 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein AAA_30 PF13604.6 KND87276.1 - 0.05 13.3 0.0 4.1 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain YjbF PF11102.8 KND87280.1 - 0.054 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF zf-C2H2_aberr PF17017.5 KND87283.1 - 0.0077 16.4 2.0 0.011 15.9 2.0 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger FOXP-CC PF16159.5 KND87283.1 - 0.02 15.5 3.2 4.2 8.1 0.9 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain Sina PF03145.16 KND87283.1 - 0.09 12.7 3.0 0.17 11.8 3.0 1.4 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 KND87283.1 - 0.4 11.6 18.3 1.2 10.1 1.8 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger Wound_ind PF08186.11 KND87284.1 - 0.32 11.4 1.6 0.64 10.5 1.6 1.5 1 0 0 1 1 1 0 Wound-inducible basic protein family Cmc1 PF08583.10 KND87286.1 - 1.4e-15 57.0 0.9 1.4e-15 57.0 0.9 1.8 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KND87286.1 - 0.025 14.7 1.0 4.1 7.6 0.3 2.4 2 0 0 2 2 2 0 CHCH domain DUF3128 PF11326.8 KND87286.1 - 0.035 14.5 4.4 2 8.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) FtsL PF04999.13 KND87286.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsL p450 PF00067.22 KND87287.1 - 3.7e-50 171.0 0.0 5.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 KND87288.1 - 3.3e-29 100.9 2.4 4.2e-29 100.6 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND87288.1 - 1.7e-22 79.8 0.1 2.8e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND87288.1 - 5.7e-09 35.8 0.4 1e-08 34.9 0.4 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KND87288.1 - 1.6e-07 32.5 0.1 5.5e-07 30.7 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 KND87288.1 - 0.00045 19.5 0.1 0.00069 18.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KND87288.1 - 0.0063 15.8 0.8 0.01 15.1 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.16 KND87288.1 - 0.041 13.6 0.8 0.064 13.0 0.1 1.6 2 0 0 2 2 2 0 Met-10+ like-protein FtsJ PF01728.19 KND87288.1 - 0.045 13.9 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 KND87288.1 - 0.046 14.4 0.0 0.099 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KND87288.1 - 0.064 13.3 1.8 0.43 10.6 0.8 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Prot_ATP_ID_OB PF16450.5 KND87288.1 - 0.076 13.0 0.2 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain HI0933_like PF03486.14 KND87288.1 - 0.082 11.6 0.7 0.12 11.0 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KND87288.1 - 0.082 13.5 0.7 0.29 11.7 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KND87288.1 - 0.11 12.1 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PALP PF00291.25 KND87288.1 - 0.14 11.6 2.9 0.063 12.7 0.5 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme MARVEL PF01284.23 KND87289.1 - 6.8e-08 32.6 17.8 1.2e-07 31.8 16.5 1.9 1 1 1 2 2 2 1 Membrane-associating domain TRI5 PF06330.11 KND87290.1 - 5.8e-161 535.4 1.3 7.1e-161 535.1 1.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Methyltransf_25 PF13649.6 KND87291.1 - 1.6e-10 41.6 0.0 2e-09 38.0 0.0 2.3 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87291.1 - 2.1e-07 31.5 0.0 1.3e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87291.1 - 8.8e-07 28.9 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87291.1 - 2.1e-06 28.4 0.0 8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87291.1 - 3e-06 27.1 0.0 6.8e-06 26.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KND87291.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KND87291.1 - 0.0015 18.5 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KND87291.1 - 0.0031 17.7 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 KND87291.1 - 0.041 13.5 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW GTP-bdg_M PF16360.5 KND87293.1 - 0.13 12.9 0.1 0.31 11.7 0.1 1.6 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region NUDIX PF00293.28 KND87295.1 - 7.7e-19 68.0 0.1 1.5e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4328 PF14219.6 KND87295.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Zn_clus PF00172.18 KND87297.1 - 5.1e-08 32.9 7.2 1.3e-07 31.6 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND87297.1 - 2.1e-07 30.3 0.0 3.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.9 KND87298.1 - 0.42 9.8 14.0 0.49 9.5 14.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF908 PF06012.12 KND87298.1 - 4.2 6.7 7.6 5.5 6.3 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) APH PF01636.23 KND87299.1 - 1e-16 61.6 0.2 1.5e-16 61.1 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87299.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Atg14 PF10186.9 KND87300.1 - 2.3e-10 40.1 4.4 1.7e-09 37.2 4.4 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KND87300.1 - 4.2e-08 32.5 0.0 8.6e-06 24.9 0.0 3.0 3 0 0 3 3 3 2 Vacuolar protein sorting 38 Spc7 PF08317.11 KND87300.1 - 3.2 6.6 7.0 4.7 6.0 7.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.32 KND87301.1 - 1e-06 29.3 3.3 0.016 16.1 0.2 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat SCP1201-deam PF14428.6 KND87301.1 - 0.028 14.3 0.2 0.028 14.3 0.2 2.3 2 0 0 2 2 2 0 SCP1.201-like deaminase zinc_ribbon_16 PF17034.5 KND87301.1 - 0.044 14.0 2.5 0.13 12.4 2.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family TFIIA PF03153.13 KND87301.1 - 0.068 13.2 17.5 0.21 11.6 17.5 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KND87301.1 - 0.2 11.2 21.9 0.34 10.5 21.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 KND87301.1 - 0.85 8.5 24.4 0.072 12.0 16.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF4379 PF14311.6 KND87301.1 - 1.9 8.9 10.9 6 7.3 0.9 2.9 2 0 0 2 2 2 0 Probable Zinc-ribbon domain GREB1 PF15782.5 KND87301.1 - 2.5 5.1 5.3 3.9 4.5 5.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TERB2 PF15101.6 KND87301.1 - 2.5 8.1 8.7 4.7 7.2 8.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EPL1 PF10513.9 KND87301.1 - 3 8.2 6.9 7.5 6.9 6.9 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like PDGF_N PF04692.13 KND87301.1 - 6.3 7.7 7.6 18 6.2 7.6 1.8 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Zn_ribbon_17 PF17120.5 KND87301.1 - 8.4 6.1 19.6 1.6 8.4 12.3 2.7 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type eIF-3_zeta PF05091.12 KND87301.1 - 9.7 5.0 9.9 16 4.4 9.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NACHT_N PF17100.5 KND87302.1 - 8.4e-61 205.6 0.0 1.3e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KND87302.1 - 1.6e-14 54.2 0.0 4.4e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KND87302.1 - 0.021 15.2 0.0 0.12 12.8 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KND87302.1 - 0.057 13.1 0.5 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KND87302.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KND87302.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KND87302.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KND87302.1 - 0.21 12.0 0.0 0.48 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Peptidase_S8 PF00082.22 KND87303.1 - 3e-13 49.7 0.0 7.1e-13 48.5 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1265 PF06887.14 KND87303.1 - 0.13 12.2 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) APH PF01636.23 KND87304.1 - 2.2e-15 57.3 0.0 3.7e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND87304.1 - 0.0072 15.9 0.0 0.04 13.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 KND87304.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KND87304.1 - 0.16 11.3 0.0 0.55 9.5 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase IBR PF01485.21 KND87306.1 - 9.1e-11 41.8 19.0 4.6e-07 30.0 7.8 4.1 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KND87306.1 - 0.0013 18.5 4.9 0.0013 18.5 4.9 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND87306.1 - 0.0014 18.4 4.6 0.0014 18.4 4.6 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND87306.1 - 0.0028 17.6 3.9 0.0028 17.6 3.9 4.1 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND87306.1 - 0.0057 17.0 6.8 0.0057 17.0 6.8 4.4 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND87306.1 - 0.0067 16.3 3.3 0.0067 16.3 3.3 4.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND87306.1 - 0.0076 16.1 4.7 0.0076 16.1 4.7 3.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KND87306.1 - 0.021 14.8 6.7 0.021 14.8 6.7 3.9 4 1 0 4 4 4 0 RING-type zinc-finger YhfH PF14149.6 KND87306.1 - 0.48 10.4 6.4 2.1 8.4 6.4 2.2 1 0 0 1 1 1 0 YhfH-like protein MOLO1 PF17175.4 KND87307.1 - 0.059 13.5 0.3 0.098 12.8 0.3 1.3 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 APH PF01636.23 KND87308.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_2 PF02230.16 KND87309.1 - 4.3e-27 95.3 0.0 9.6e-21 74.6 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KND87309.1 - 4.4e-05 23.1 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cutinase PF01083.22 KND87309.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase ketoacyl-synt PF00109.26 KND87310.1 - 1.3e-68 231.4 1.3 2.3e-68 230.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KND87310.1 - 1.2e-63 214.3 0.1 3e-63 213.0 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KND87310.1 - 2.5e-59 200.9 0.2 4.5e-59 200.1 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KND87310.1 - 5.5e-42 142.5 0.1 3.3e-41 140.0 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KND87310.1 - 1.3e-35 123.4 1.7 4.5e-33 115.1 1.4 3.1 2 1 0 2 2 2 1 Acyl transferase domain ADH_zinc_N_2 PF13602.6 KND87310.1 - 2e-19 70.9 0.1 1.4e-18 68.2 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KND87310.1 - 2e-16 60.6 0.0 6.5e-16 58.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KND87310.1 - 2.5e-15 56.9 0.0 6.2e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 KND87310.1 - 1.2e-13 51.2 0.6 6e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KND87310.1 - 2e-11 44.0 0.0 4.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KND87310.1 - 2.7e-09 36.7 0.0 8.1e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KND87310.1 - 3e-09 37.5 0.0 1.1e-08 35.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87310.1 - 1.8e-07 31.7 0.0 1.1e-06 29.1 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87310.1 - 2.7e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KND87310.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KND87310.1 - 0.0038 17.6 0.6 0.0099 16.2 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KND87310.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KND87310.1 - 0.018 14.4 1.1 0.075 12.4 0.0 2.3 2 1 1 3 3 3 0 Thiolase, N-terminal domain APH PF01636.23 KND87311.1 - 1.2e-07 31.9 0.1 1.3e-07 31.8 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87311.1 - 8.7e-07 28.7 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND87311.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Rubis-subs-bind PF09273.11 KND87312.1 - 0.04 14.6 0.9 0.077 13.7 0.9 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding AAA_12 PF13087.6 KND87314.1 - 5e-40 137.3 0.1 1.3e-39 135.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND87314.1 - 9.4e-26 91.1 10.0 3.3e-24 86.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 KND87314.1 - 2.6e-18 66.7 0.0 2.7e-06 27.8 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KND87314.1 - 9.4e-15 54.5 7.1 1.1e-07 31.9 0.3 3.0 2 0 0 2 2 2 2 AAA lid domain AAA_30 PF13604.6 KND87314.1 - 2.1e-13 50.4 0.2 0.0014 18.4 0.1 4.2 4 0 0 4 4 4 3 AAA domain AAA_19 PF13245.6 KND87314.1 - 4e-10 40.2 0.9 4e-06 27.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KND87314.1 - 5.3e-07 30.0 1.1 0.49 10.7 0.0 5.4 5 1 0 5 5 4 2 AAA domain AAA_24 PF13479.6 KND87314.1 - 0.00074 19.3 1.5 3.6 7.3 0.1 4.5 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.14 KND87314.1 - 0.00089 19.3 0.4 1.5 8.8 0.1 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KND87314.1 - 0.0015 17.9 2.7 1 8.7 0.0 3.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KND87314.1 - 0.0055 16.5 0.0 0.29 10.9 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KND87314.1 - 0.012 16.2 0.3 9.3 6.8 0.3 4.2 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 KND87314.1 - 0.018 14.6 0.0 11 5.6 0.0 4.2 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.22 KND87314.1 - 0.026 14.9 0.0 9.1 6.7 0.0 3.1 2 0 0 2 2 2 0 RNA helicase Helicase_RecD PF05127.14 KND87314.1 - 0.029 14.2 0.1 4.2 7.2 0.0 3.6 3 0 0 3 3 3 0 Helicase ResIII PF04851.15 KND87314.1 - 0.029 14.4 0.0 0.7 9.9 0.0 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Adeno_IVa2 PF02456.15 KND87314.1 - 0.036 12.9 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 KND87314.1 - 0.28 10.4 2.8 0.83 8.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KND87314.1 - 0.47 9.9 5.7 5.6 6.4 0.0 4.4 5 0 0 5 5 5 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KND87314.1 - 0.71 10.2 5.4 18 5.7 0.0 4.4 4 0 0 4 4 3 0 AAA ATPase domain AAA_33 PF13671.6 KND87314.1 - 1.7 8.8 5.8 1.1 9.4 0.1 3.2 3 0 0 3 3 2 0 AAA domain DUF4019 PF13211.6 KND87315.1 - 0.08 13.3 0.4 0.12 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) RANK_CRD_2 PF18278.1 KND87315.1 - 0.18 12.0 3.9 0.47 10.6 0.3 2.4 1 1 1 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Fungal_trans PF04082.18 KND87318.1 - 3.8e-27 95.0 0.6 3.8e-27 95.0 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KND87318.1 - 1.4e-07 31.6 0.2 3.1e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 KND87318.1 - 3.3e-07 30.3 9.5 6.2e-07 29.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KND87319.1 - 0.0058 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KND87319.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase CDC45 PF02724.14 KND87320.1 - 0.63 8.3 3.8 0.99 7.6 3.8 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 KND87320.1 - 4.3 7.0 6.0 15 5.3 6.0 1.9 1 0 0 1 1 1 0 FAM176 family PAF-AH_p_II PF03403.13 KND87321.1 - 9.4e-46 156.0 0.0 1.6e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KND87321.1 - 3.3e-07 29.5 0.0 3.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KND87321.1 - 3.6e-05 22.9 0.0 0.00026 20.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.8 KND87321.1 - 0.00078 18.8 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 AP3D1 PF06375.11 KND87321.1 - 0.086 13.1 0.3 0.15 12.3 0.3 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Ribosomal_S30 PF04758.14 KND87322.1 - 9.9e-28 96.1 5.6 1.4e-27 95.6 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S30 RCDG1 PF15725.5 KND87322.1 - 0.012 16.1 0.6 0.022 15.2 0.6 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein RRM_1 PF00076.22 KND87323.1 - 2.3e-14 53.0 0.1 3.3e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KND87323.1 - 0.031 14.3 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif APH PF01636.23 KND87324.1 - 1.1e-05 25.5 0.2 1.9e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_pol3_chi PF04364.13 KND87324.1 - 0.077 13.2 1.6 0.32 11.2 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC Choline_kinase PF01633.20 KND87324.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rpn9_C PF18261.1 KND87324.1 - 0.16 11.6 1.3 0.3 10.7 0.2 2.1 2 0 0 2 2 2 0 Rpn9 C-terminal helix PhyH PF05721.13 KND87325.1 - 1.5e-27 97.2 0.0 1.9e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3626 PF12294.8 KND87325.1 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3626) HGWP PF03578.15 KND87325.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 HGWP repeat Fungal_trans_2 PF11951.8 KND87326.1 - 7e-08 31.7 0.0 7e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KND87327.1 - 2.4e-14 53.0 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87327.1 - 1.4e-06 28.3 4.8 2.4e-06 27.6 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-B_box PF00643.24 KND87328.1 - 0.044 13.9 1.8 0.044 13.9 1.8 1.6 2 0 0 2 2 2 0 B-box zinc finger LMBR1 PF04791.16 KND87329.1 - 1.6e-20 73.5 15.5 6e-20 71.6 3.0 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein UPF0093 PF03653.13 KND87329.1 - 0.013 15.7 1.5 1.2 9.4 0.0 3.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Pal1 PF08316.11 KND87330.1 - 2e-07 31.9 1.0 1.3e-06 29.3 0.0 2.4 2 0 0 2 2 2 1 Pal1 cell morphology protein TFIIA PF03153.13 KND87330.1 - 0.025 14.6 5.4 0.042 13.8 5.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.17 KND87330.1 - 0.11 12.5 8.6 0.28 11.2 8.6 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 KND87330.1 - 0.16 10.0 1.2 0.21 9.5 1.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Siah-Interact_N PF09032.11 KND87330.1 - 0.19 12.1 0.8 0.52 10.7 0.8 1.7 1 0 0 1 1 1 0 Siah interacting protein, N terminal Spt20 PF12090.8 KND87330.1 - 0.25 10.9 9.0 0.45 10.1 9.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF4551 PF15087.6 KND87330.1 - 1.9 7.2 7.7 3.4 6.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HVSL PF09749.9 KND87331.1 - 1.4e-81 273.5 0.0 1.6e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein NACHT PF05729.12 KND87332.1 - 2.2e-08 34.2 0.0 4.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND87332.1 - 4.6e-05 23.9 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KND87332.1 - 0.0048 16.1 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PIF1 PF05970.14 KND87332.1 - 0.0064 15.7 0.0 0.021 14.0 0.0 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_18 PF13238.6 KND87332.1 - 0.013 16.0 0.4 0.058 14.0 0.4 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KND87332.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND87332.1 - 0.2 11.4 0.2 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPSF_A PF03178.15 KND87333.1 - 2.4e-73 247.3 0.0 1.3e-72 244.9 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KND87333.1 - 2e-16 59.7 0.0 3.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ERO1 PF04137.15 KND87334.1 - 5.6e-133 443.5 0.0 6.8e-133 443.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pkinase PF00069.25 KND87337.1 - 3.3e-47 161.1 0.0 6e-47 160.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87337.1 - 1.4e-20 73.7 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND87337.1 - 2e-05 24.1 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Trp_halogenase PF04820.14 KND87338.1 - 2.1e-26 92.8 0.0 3.1e-12 46.1 0.1 2.6 1 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KND87338.1 - 4.3e-12 45.9 0.0 1.3e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND87338.1 - 2e-06 28.0 0.2 1.1e-05 25.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND87338.1 - 8.7e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND87338.1 - 0.00013 21.7 0.1 0.00043 20.0 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KND87338.1 - 0.00087 18.7 0.2 0.0021 17.5 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND87338.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KND87338.1 - 0.0011 18.2 0.1 0.002 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KND87338.1 - 0.0037 16.4 0.1 0.0056 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KND87338.1 - 0.024 15.2 0.1 0.079 13.5 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KND87338.1 - 0.034 14.6 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 KND87338.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KND87338.1 - 0.06 12.6 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND87338.1 - 0.071 12.1 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TIP120 PF08623.10 KND87338.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) ketoacyl-synt PF00109.26 KND87339.1 - 3.1e-66 223.6 0.8 1.1e-65 221.7 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND87339.1 - 2.1e-27 95.5 0.0 5e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KND87339.1 - 3.2e-26 92.6 2.7 5e-26 92.0 1.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain HTH_51 PF18558.1 KND87339.1 - 1.1e-24 86.1 0.0 1.3e-23 82.6 0.0 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain SAT PF16073.5 KND87339.1 - 8.1e-15 55.2 1.0 6.4e-11 42.4 0.1 2.7 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KND87339.1 - 2.9e-12 46.8 0.2 8.1e-12 45.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KND87339.1 - 5.3e-12 45.6 0.2 1.1e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KND87339.1 - 1.1e-11 45.3 0.0 3.2e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87339.1 - 3.1e-10 40.6 0.0 1.3e-09 38.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87339.1 - 2.7e-09 37.1 0.0 1.2e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87339.1 - 6.1e-08 33.2 0.0 1.8e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87339.1 - 2.2e-07 30.8 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KND87339.1 - 0.00018 21.0 0.5 0.00038 19.9 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Na_trans_assoc PF06512.13 KND87339.1 - 0.11 12.8 3.0 0.19 12.0 3.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 KND87339.1 - 0.17 11.2 3.8 0.26 10.6 3.8 1.1 1 0 0 1 1 1 0 BUD22 ACP_syn_III PF08545.10 KND87339.1 - 2.1 8.2 4.6 2 8.3 0.2 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_3 PF01494.19 KND87340.1 - 6.9e-23 81.5 0.1 2.1e-22 79.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND87340.1 - 1.6e-06 28.0 0.2 3.9e-06 26.7 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 KND87340.1 - 0.0012 18.0 0.0 0.076 12.1 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KND87340.1 - 0.0035 16.6 0.1 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KND87340.1 - 0.023 14.6 0.4 0.036 14.0 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KND87340.1 - 0.04 14.5 1.8 0.094 13.3 1.6 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND87340.1 - 0.088 11.5 0.5 0.13 10.9 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein M20_dimer PF07687.14 KND87340.1 - 0.099 12.6 0.0 0.29 11.1 0.0 1.9 1 1 0 1 1 1 0 Peptidase dimerisation domain FAD_oxidored PF12831.7 KND87340.1 - 0.11 11.9 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND87340.1 - 0.13 12.5 1.2 0.39 11.0 1.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND87340.1 - 0.25 10.4 2.0 0.7 8.9 1.2 1.9 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KND87341.1 - 8.2e-31 107.2 50.7 2.5e-27 95.7 41.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Renin_r PF07850.14 KND87341.1 - 0.023 15.3 0.1 0.047 14.3 0.1 1.6 1 0 0 1 1 1 0 Renin receptor-like protein OATP PF03137.20 KND87341.1 - 0.11 10.7 7.2 0.023 13.0 2.1 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2613 PF11021.8 KND87341.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2613) adh_short PF00106.25 KND87342.1 - 4.3e-08 32.8 0.0 8.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KND87342.1 - 0.00055 19.9 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KND87342.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.18 KND87343.1 - 2.1e-16 59.7 0.2 3.7e-16 59.0 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87343.1 - 4.1e-09 36.4 10.0 7e-09 35.7 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.28 KND87344.1 - 1.1e-10 42.1 0.0 2.5e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 SET domain RdRP PF05183.12 KND87345.1 - 5.9e-189 629.5 0.0 7.5e-189 629.2 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KND87345.1 - 0.00026 20.7 0.0 0.01 15.6 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.12 KND87346.1 - 8.4e-26 90.9 13.4 1.1e-25 90.5 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KND87346.1 - 0.68 9.7 4.4 7.7 6.3 0.0 3.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1772 PF08592.11 KND87346.1 - 3.6 7.9 9.5 0.21 11.9 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) ABC1 PF03109.16 KND87347.1 - 1e-21 77.3 0.0 3.4e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 ABC1 family Nse4_C PF08743.10 KND87347.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Nse4 C-terminal F-box-like PF12937.7 KND87350.1 - 0.91 9.5 8.2 1.2 9.0 3.3 3.3 2 1 0 2 2 2 0 F-box-like Pkinase_fungal PF17667.1 KND87351.1 - 7.7e-51 173.1 0.0 8.9e-47 159.8 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KND87351.1 - 5.1e-05 22.8 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KND87351.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KND87351.1 - 0.082 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_4 PF13418.6 KND87354.1 - 3.3e-30 103.8 6.8 7.5e-05 22.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KND87354.1 - 2.2e-29 100.9 5.1 3.2e-07 30.2 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KND87354.1 - 1.7e-28 98.3 5.8 1.4e-06 28.4 0.0 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 KND87354.1 - 2.5e-27 94.2 4.4 3.7e-09 36.5 0.2 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KND87354.1 - 2.3e-25 87.9 1.0 6e-09 35.4 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 KND87354.1 - 6.8e-18 63.9 6.4 2.7e-06 27.1 0.1 6.3 6 0 0 6 6 6 4 Kelch motif Pox_A_type_inc PF04508.12 KND87354.1 - 2.7e-06 27.0 6.9 0.9 9.5 0.5 4.8 3 0 0 3 3 3 3 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.7 KND87354.1 - 0.0017 18.5 3.9 0.0017 18.5 3.9 6.4 2 2 5 7 7 6 2 Tropomyosin like Cnn_1N PF07989.11 KND87354.1 - 0.0029 17.7 2.1 0.0029 17.7 2.1 6.5 5 2 2 7 7 7 1 Centrosomin N-terminal motif 1 ADIP PF11559.8 KND87354.1 - 0.005 16.9 4.0 0.005 16.9 4.0 6.9 2 2 3 7 7 7 2 Afadin- and alpha -actinin-Binding Takusan PF04822.13 KND87354.1 - 0.14 12.0 0.1 0.14 12.0 0.1 4.0 3 0 0 3 3 3 0 Takusan zf-C2H2 PF00096.26 KND87355.1 - 7.3e-11 41.9 12.4 2.5e-05 24.5 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND87355.1 - 6.7e-09 35.9 10.2 0.0006 20.4 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND87355.1 - 7e-09 35.7 5.1 1.4e-05 25.3 1.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KND87355.1 - 6.3e-05 22.9 6.7 0.01 15.8 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger BolA PF01722.18 KND87355.1 - 0.00074 19.7 0.8 1 9.7 0.0 2.5 1 1 1 2 2 2 2 BolA-like protein zf-C2HC_2 PF13913.6 KND87355.1 - 0.083 12.8 2.0 0.2 11.6 2.0 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KND87355.1 - 0.088 13.3 8.3 2.5 8.6 0.7 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 KND87355.1 - 0.27 11.6 3.8 0.43 10.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KND87355.1 - 0.52 10.1 11.7 1.5 8.7 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 KND87355.1 - 0.59 10.2 3.2 0.74 9.9 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 KND87355.1 - 0.64 9.8 5.5 3.2 7.6 0.6 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-AN1 PF01428.16 KND87355.1 - 0.74 10.0 9.2 2.3 8.4 1.9 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger Bd3614-deam PF14439.6 KND87355.1 - 4 7.5 6.1 9.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Bd3614-like deaminase SRF-TF PF00319.18 KND87357.1 - 1.7e-20 72.2 0.2 2.4e-20 71.7 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Raptor_N PF14538.6 KND87359.1 - 4.8e-63 211.5 0.0 8.1e-63 210.8 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KND87359.1 - 1.4e-05 25.7 4.2 1.7 9.6 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KND87359.1 - 1.9e-05 24.6 0.0 0.12 12.4 0.0 2.7 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 KND87359.1 - 4.2e-05 23.8 0.0 11 6.4 0.0 4.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 KND87359.1 - 0.00028 21.2 0.5 0.22 11.9 0.0 4.0 4 0 0 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 KND87359.1 - 0.00087 19.3 0.4 0.0019 18.2 0.4 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 KND87359.1 - 0.052 13.8 5.5 2 8.9 0.2 4.9 7 0 0 7 7 7 0 HEAT repeat SMC_N PF02463.19 KND87361.1 - 2.8e-26 92.3 0.2 4.1e-26 91.8 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KND87361.1 - 7e-14 52.8 17.6 7e-14 52.8 17.6 4.8 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KND87361.1 - 2.5e-09 37.3 7.2 1.9e-05 24.5 1.6 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KND87361.1 - 5.9e-07 29.6 3.9 0.0017 18.2 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system JIP_LZII PF16471.5 KND87361.1 - 0.0079 16.3 2.1 0.0079 16.3 2.1 5.0 6 0 0 6 6 6 1 JNK-interacting protein leucine zipper II AAA_29 PF13555.6 KND87361.1 - 0.0095 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND87361.1 - 0.04 13.8 0.1 0.39 10.6 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase BLOC1_2 PF10046.9 KND87361.1 - 0.15 12.4 0.1 0.15 12.4 0.1 5.9 6 1 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 KND87361.1 - 0.33 11.0 7.1 34 4.5 0.6 4.8 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.6 KND87361.1 - 0.48 10.0 0.0 0.48 10.0 0.0 4.0 5 0 0 5 5 5 0 AAA domain Pkinase PF00069.25 KND87362.1 - 1.1e-64 218.3 1.1 7e-64 215.7 0.1 2.4 2 1 0 2 2 2 1 Protein kinase domain Fungal_KA1 PF16797.5 KND87362.1 - 2.2e-40 137.0 0.5 4.6e-40 136.0 0.5 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 KND87362.1 - 2e-34 119.1 0.0 1.2e-33 116.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND87362.1 - 7.2e-06 25.5 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Malate_synthase PF01274.22 KND87363.1 - 5.2e-226 751.0 0.0 6e-226 750.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HlyD_D4 PF16572.5 KND87364.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Cofac_haem_bdg PF04187.13 KND87364.1 - 0.33 10.9 3.9 0.31 11.0 0.1 2.3 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN BLOC1_2 PF10046.9 KND87365.1 - 0.00037 20.7 3.5 0.00037 20.7 3.5 2.6 3 1 0 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_tail_1 PF01576.19 KND87365.1 - 0.0012 16.8 4.3 0.0012 16.8 4.3 2.1 2 0 0 2 2 2 1 Myosin tail OmpH PF03938.14 KND87365.1 - 0.0031 17.9 23.8 0.25 11.7 6.2 2.7 2 1 1 3 3 3 2 Outer membrane protein (OmpH-like) Filament PF00038.21 KND87365.1 - 0.0033 17.1 13.2 0.079 12.5 3.8 2.4 2 0 0 2 2 2 2 Intermediate filament protein GvpK PF05121.12 KND87365.1 - 0.0046 17.0 1.3 0.0046 17.0 1.3 2.9 3 1 0 3 3 2 1 Gas vesicle protein K Spc7 PF08317.11 KND87365.1 - 0.008 15.1 4.7 0.008 15.1 4.7 2.7 3 0 0 3 3 3 2 Spc7 kinetochore protein Spc24 PF08286.11 KND87365.1 - 0.0096 16.2 12.3 0.29 11.4 2.0 2.8 3 0 0 3 3 3 2 Spc24 subunit of Ndc80 UPF0242 PF06785.11 KND87365.1 - 0.02 15.0 13.1 0.09 12.9 1.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 KND87365.1 - 0.024 14.0 16.1 0.072 12.4 2.9 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 KND87365.1 - 0.11 12.5 17.3 0.15 12.1 3.8 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.11 KND87365.1 - 0.16 12.3 3.7 0.16 12.2 1.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 KND87365.1 - 0.19 11.8 20.3 0.13 12.3 2.1 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cluap1 PF10234.9 KND87365.1 - 0.22 10.9 10.1 0.51 9.7 1.9 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 Mod_r PF07200.13 KND87365.1 - 0.33 11.0 14.0 0.062 13.4 1.5 2.7 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 KND87365.1 - 0.37 11.3 20.3 0.21 12.1 3.0 2.6 3 0 0 3 3 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KND87365.1 - 0.4 11.2 3.0 0.39 11.2 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 KND87365.1 - 0.51 9.8 13.4 0.98 8.8 3.6 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 KND87365.1 - 0.54 10.5 23.0 1.7 8.9 8.0 3.2 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 HemX PF04375.14 KND87365.1 - 0.74 9.0 14.8 0.43 9.8 0.8 2.4 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF2203 PF09969.9 KND87365.1 - 0.8 10.4 11.4 1 10.1 0.5 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GrpE PF01025.19 KND87365.1 - 0.93 9.1 15.7 0.69 9.6 4.4 2.5 2 0 0 2 2 2 0 GrpE Fez1 PF06818.15 KND87365.1 - 1 9.8 19.5 3.3 8.1 17.4 2.4 2 1 1 3 3 3 0 Fez1 PAXX PF15384.6 KND87365.1 - 1.1 8.9 5.9 0.36 10.5 0.4 2.2 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 PRKG1_interact PF15898.5 KND87365.1 - 1.7 9.6 18.1 1.9 9.4 3.2 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Laminin_II PF06009.12 KND87365.1 - 2.1 8.3 13.9 1.6 8.8 1.2 2.8 3 0 0 3 3 3 0 Laminin Domain II Fzo_mitofusin PF04799.13 KND87365.1 - 2.8 7.5 6.8 1.1 8.8 0.7 2.3 2 0 0 2 2 2 0 fzo-like conserved region LMBR1 PF04791.16 KND87365.1 - 3 6.6 6.4 1.4 7.8 4.0 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.9 KND87365.1 - 3.8 7.5 21.9 1.9 8.5 7.0 2.9 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKI PF02827.16 KND87365.1 - 6.1 7.1 8.9 2.6 8.3 1.3 3.3 3 1 0 3 3 3 0 cAMP-dependent protein kinase inhibitor Bacillus_HBL PF05791.11 KND87365.1 - 6.4 6.6 7.2 3.5 7.4 0.5 2.5 3 0 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 KND87365.1 - 7.2 7.1 10.0 1.9 8.9 0.3 3.7 3 2 2 5 5 4 0 Flagella accessory protein C (FlaC) IFT20 PF14931.6 KND87365.1 - 7.6 6.7 15.6 0.8 9.9 4.3 2.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 YabA PF06156.13 KND87365.1 - 8 7.2 16.3 1.4 9.6 2.3 3.3 3 1 0 3 3 2 0 Initiation control protein YabA Aldedh PF00171.22 KND87366.1 - 1e-118 396.8 0.1 1.3e-118 396.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 KND87367.1 - 3.7e-41 140.8 0.0 7.4e-41 139.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND87367.1 - 4.1e-27 94.7 0.3 1.4e-26 93.0 0.1 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KND87367.1 - 0.012 15.0 0.5 0.023 14.1 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 KND87367.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain UTP25 PF06862.12 KND87367.1 - 0.023 13.5 0.0 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PhoLip_ATPase_C PF16212.5 KND87368.1 - 3.8e-77 259.4 26.8 3.8e-77 259.4 26.8 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND87368.1 - 1.3e-18 66.4 2.0 3.7e-18 65.0 2.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KND87368.1 - 1.6e-12 47.3 0.3 1.5e-11 44.2 0.0 2.6 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND87368.1 - 1.4e-11 45.1 4.5 8.8e-08 32.7 1.3 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND87368.1 - 0.0017 17.9 0.3 0.015 14.8 0.0 2.8 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND87368.1 - 0.015 15.0 0.4 0.037 13.7 0.4 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3245 PF11595.8 KND87368.1 - 6.4 7.2 12.4 0.14 12.7 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) RF-1 PF00472.20 KND87370.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RF-1 domain vATP-synt_E PF01991.18 KND87371.1 - 3.9e-68 228.8 10.3 4.5e-68 228.6 10.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit FliH PF02108.16 KND87371.1 - 0.0098 16.0 0.2 0.046 13.8 0.0 2.2 2 1 1 3 3 3 1 Flagellar assembly protein FliH SurA_N_3 PF13624.6 KND87371.1 - 0.034 13.9 7.6 0.48 10.2 4.2 2.8 2 1 1 3 3 3 0 SurA N-terminal domain DUF1062 PF06353.12 KND87371.1 - 0.57 11.0 4.3 0.81 10.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) Methyltransf_7 PF03492.15 KND87371.1 - 0.87 8.7 6.1 0.43 9.7 3.0 1.8 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase Bap31_Bap29_C PF18035.1 KND87371.1 - 1.1 9.3 9.3 0.17 11.9 2.9 2.4 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain RapH_N PF18801.1 KND87371.1 - 6.5 6.9 6.8 12 6.1 0.8 2.5 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Mg_trans_NIPA PF05653.14 KND87372.1 - 1.1e-16 60.8 11.1 1.8e-16 60.1 11.1 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 KND87372.1 - 4.5e-05 22.8 0.4 4.5e-05 22.8 0.4 3.1 3 1 1 4 4 4 2 Purine nucleobase transmembrane transport EamA PF00892.20 KND87372.1 - 0.00049 20.3 0.1 0.00049 20.3 0.1 2.9 3 1 1 4 4 4 2 EamA-like transporter family Tetraspanin PF00335.20 KND87373.1 - 0.00045 20.0 3.5 0.001 18.8 4.0 1.3 1 1 0 1 1 1 1 Tetraspanin family FxsA PF04186.13 KND87373.1 - 0.025 14.7 5.9 0.055 13.6 0.1 3.4 3 1 1 4 4 4 0 FxsA cytoplasmic membrane protein DUF4131 PF13567.6 KND87373.1 - 0.034 13.8 1.8 0.55 9.9 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 KND87373.1 - 0.041 13.2 0.6 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Phage_holin_3_6 PF07332.11 KND87373.1 - 0.042 13.9 4.4 0.049 13.7 0.6 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_L24e PF01246.20 KND87374.1 - 6.1e-29 100.0 0.2 1.5e-28 98.8 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Redoxin PF08534.10 KND87375.1 - 3e-32 111.4 0.1 4.5e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KND87375.1 - 1.9e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family HisK_sensor PF18698.1 KND87375.1 - 0.049 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase sensor domain CBP4 PF07960.11 KND87376.1 - 7.1e-21 74.4 1.5 7.1e-21 74.4 1.5 1.7 2 0 0 2 2 2 1 CBP4 DUF2683 PF10884.8 KND87376.1 - 0.21 11.9 1.3 0.36 11.1 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2683) OPT PF03169.15 KND87377.1 - 4.3e-164 547.5 51.7 5.2e-164 547.3 51.7 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein tRNA-synt_2 PF00152.20 KND87378.1 - 1.1e-65 221.8 0.0 1.4e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND87378.1 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 KND87378.1 - 0.73 8.7 5.4 1.1 8.1 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 bZIP_1 PF00170.21 KND87379.1 - 2.2e-07 30.8 12.4 3.4e-07 30.3 12.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KND87379.1 - 4.4e-05 23.4 17.5 0.0001 22.2 0.0 2.3 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 KND87379.1 - 0.00023 21.6 4.1 0.00045 20.7 4.1 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor SHE3 PF17078.5 KND87379.1 - 0.002 17.9 4.3 0.0029 17.4 4.3 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 KND87379.1 - 0.0097 13.9 0.9 0.012 13.6 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4554 PF15091.6 KND87379.1 - 0.068 12.1 1.9 0.086 11.7 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LMSTEN PF07988.12 KND87379.1 - 0.12 11.9 1.0 18 4.9 0.0 2.7 2 0 0 2 2 2 0 LMSTEN motif TFIIA PF03153.13 KND87379.1 - 0.84 9.6 10.7 1.1 9.2 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlaC_arch PF05377.11 KND87379.1 - 1.2 9.6 2.9 2.5 8.6 2.9 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.15 KND87379.1 - 1.3 9.2 13.8 1.2 9.3 10.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper CYYR1 PF10873.8 KND87379.1 - 7.3 7.0 5.8 16 5.9 5.8 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Mak16 PF04874.14 KND87380.1 - 0.43 11.2 6.9 1 10.0 0.0 2.8 3 0 0 3 3 3 0 Mak16 protein C-terminal region Septin PF00735.18 KND87381.1 - 4.1e-33 114.9 0.0 2.6e-11 43.3 0.0 3.1 3 0 0 3 3 3 3 Septin Dynamin_N PF00350.23 KND87381.1 - 0.0041 17.2 0.0 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KND87381.1 - 0.02 15.4 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0139 PF03669.13 KND87383.1 - 1.2e-09 37.9 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF308 PF03729.13 KND87383.1 - 0.094 13.1 0.2 0.12 12.7 0.2 1.1 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) NTPase_P4 PF11602.8 KND87383.1 - 0.2 10.9 0.0 0.24 10.6 0.0 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 GRP PF07172.11 KND87384.1 - 0.024 15.3 8.5 0.024 15.3 8.5 4.3 2 1 1 3 3 3 0 Glycine rich protein family S1-P1_nuclease PF02265.16 KND87385.1 - 3.7e-69 233.4 0.1 4.2e-69 233.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PSI_PSAK PF01241.18 KND87385.1 - 0.17 11.9 0.2 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 Photosystem I psaG / psaK PQ-loop PF04193.14 KND87386.1 - 8.9e-38 127.9 4.0 9.4e-19 66.9 0.1 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF4131 PF13567.6 KND87386.1 - 0.69 9.5 0.0 0.69 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.6 KND87389.1 - 1.9e-12 47.3 4.9 3e-12 46.7 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 KND87389.1 - 1e-09 38.2 0.0 2.4e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 KND87389.1 - 1.8e-09 37.3 3.9 2.8e-09 36.7 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND87389.1 - 5.7e-09 36.1 2.0 1.2e-08 35.1 2.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND87389.1 - 8.2e-09 35.2 2.7 1.3e-08 34.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND87389.1 - 2e-08 33.8 1.9 2e-08 33.8 1.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KND87389.1 - 7.9e-07 28.9 2.1 1.2e-06 28.3 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND87389.1 - 4.5e-06 26.6 1.6 9.9e-06 25.5 0.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KND87389.1 - 1e-05 25.3 2.6 1.6e-05 24.7 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND87389.1 - 0.0013 18.7 0.9 0.0024 17.9 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KND87389.1 - 0.0058 16.5 2.5 0.01 15.7 2.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KND87389.1 - 0.019 14.5 2.9 0.038 13.6 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KND87389.1 - 0.042 14.0 2.4 0.094 12.9 2.4 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KND87389.1 - 0.092 12.9 2.2 0.25 11.5 2.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 KND87389.1 - 0.36 11.0 3.1 0.72 10.0 3.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KND87389.1 - 0.45 10.9 3.1 0.78 10.1 3.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KND87389.1 - 0.68 9.8 2.8 1.4 8.8 2.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KND87389.1 - 0.81 9.6 2.4 1.4 8.8 2.4 1.4 1 0 0 1 1 1 0 PHD-finger Egh16-like PF11327.8 KND87390.1 - 2.6e-15 57.3 4.9 6.8e-13 49.4 0.6 2.5 1 1 1 2 2 2 2 Egh16-like virulence factor DEC-1_N PF04625.13 KND87390.1 - 0.005 15.9 5.0 0.0065 15.5 5.0 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region Ribosomal_S4e PF00900.20 KND87391.1 - 1.3e-35 121.2 0.2 2.5e-35 120.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KND87391.1 - 1.7e-23 82.0 0.1 3.1e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KND87391.1 - 6.8e-16 58.1 3.6 1.7e-15 56.8 3.6 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain Myb_DNA-binding PF00249.31 KND87391.1 - 1.4e-14 54.0 0.1 1.7e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND87391.1 - 1.9e-10 40.8 0.0 6.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KND87391.1 - 4.2e-06 26.8 0.1 0.017 15.1 0.0 2.7 2 0 0 2 2 2 2 SLIDE S4 PF01479.25 KND87391.1 - 0.0003 20.5 0.0 0.00057 19.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain SANT_DAMP1_like PF16282.5 KND87391.1 - 0.024 14.8 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 KOW PF00467.29 KND87391.1 - 0.42 10.6 5.0 0.48 10.5 2.8 2.4 2 0 0 2 2 2 0 KOW motif EI24 PF07264.11 KND87392.1 - 4.8e-12 46.5 7.8 1e-11 45.4 7.8 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) LANC_like PF05147.13 KND87393.1 - 3.6e-10 39.0 0.0 6.4e-10 38.1 0.0 1.4 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein LpxK PF02606.14 KND87393.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Zn_clus PF00172.18 KND87394.1 - 1.7e-07 31.2 12.2 2.8e-07 30.6 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ntox15 PF15604.6 KND87394.1 - 0.0077 16.4 2.9 0.18 11.9 0.0 3.0 3 0 0 3 3 3 1 Novel toxin 15 Robl_LC7 PF03259.17 KND87395.1 - 4.1e-09 36.1 0.1 4.2e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 KND87395.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 Ipi1_N PF12333.8 KND87396.1 - 2.5e-27 95.4 0.8 7.1e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation L_biotic_typeA PF04604.13 KND87396.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Type-A lantibiotic Dopey_N PF04118.14 KND87396.1 - 0.14 11.3 0.1 0.69 9.0 0.0 1.9 1 1 1 2 2 2 0 Dopey, N-terminal EOS1 PF12326.8 KND87397.1 - 1.1e-16 61.3 7.7 1.8e-16 60.5 2.6 2.2 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.22 KND87398.1 - 2.4e-27 95.2 3.3 3.1e-27 94.9 3.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 UPF0016 PF01169.19 KND87399.1 - 5.4e-41 138.8 25.3 1.4e-20 73.4 10.3 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 KND87399.1 - 0.008 15.9 0.2 0.008 15.9 0.2 2.1 2 0 0 2 2 2 1 Putative manganese efflux pump WD40 PF00400.32 KND87400.1 - 3e-20 72.1 23.9 8.5e-06 26.4 2.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87400.1 - 1.1e-05 25.6 0.0 0.0037 17.5 0.0 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KND87400.1 - 0.0029 16.2 2.0 0.24 9.9 0.1 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain DNA_pol_phi PF04931.13 KND87400.1 - 3.8 5.5 23.9 5.2 5.0 23.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Beta-lactamase PF00144.24 KND87401.1 - 3.3e-13 49.6 0.2 3.1e-08 33.3 0.0 2.2 1 1 0 2 2 2 2 Beta-lactamase RRM_1 PF00076.22 KND87402.1 - 5.4e-05 22.9 0.0 9.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prothymosin PF03247.14 KND87402.1 - 4.9 7.7 12.7 9.3 6.8 12.7 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family AdoMet_MTase PF07757.13 KND87403.1 - 2.3e-39 134.2 0.0 3.6e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KND87403.1 - 0.012 15.6 0.1 0.27 11.2 0.2 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KND87403.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ATP-sulfurylase PF01747.17 KND87405.1 - 6.8e-89 296.9 0.2 1e-88 296.4 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KND87405.1 - 2.2e-57 193.4 0.0 3.7e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KND87405.1 - 6.7e-51 172.1 0.0 1.1e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain KTI12 PF08433.10 KND87405.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TRP PF06011.12 KND87406.1 - 7.1e-109 364.4 17.1 9.6e-109 363.9 17.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND87406.1 - 2.5e-39 134.8 0.0 3.9e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain NAC PF01849.18 KND87407.1 - 4.3e-14 52.2 1.3 5.5e-14 51.9 0.2 1.7 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.18 KND87408.1 - 5.1e-20 72.2 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain NACHT PF05729.12 KND87409.1 - 3.1e-08 33.7 0.1 5.6e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND87409.1 - 0.00023 21.6 0.1 0.00069 20.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND87409.1 - 0.0037 17.5 0.0 0.017 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KND87409.1 - 0.0096 15.1 0.0 0.03 13.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 KND87409.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KND87409.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KND87409.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KND87409.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KND87409.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoA_binding PF02629.19 KND87411.1 - 6.3e-28 97.3 3.4 9.4e-28 96.8 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KND87411.1 - 1.5e-24 86.6 0.9 2.2e-24 86.0 0.9 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KND87411.1 - 6.5e-10 38.9 0.1 1.1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KND87411.1 - 0.00098 19.6 0.2 0.0042 17.6 0.0 2.1 2 1 0 2 2 2 1 CoA binding domain UQ_con PF00179.26 KND87412.1 - 1.7e-34 118.5 0.0 2.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KND87412.1 - 1.7e-07 30.9 0.2 3e-07 30.2 0.2 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 KND87412.1 - 0.034 14.0 0.3 0.062 13.2 0.3 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Prok-E2_B PF14461.6 KND87412.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KND87412.1 - 0.059 13.2 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 UEV domain HET PF06985.11 KND87413.1 - 4.6e-32 111.4 0.1 7.2e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 KND87414.1 - 0.02 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF4281 PF14108.6 KND87414.1 - 0.033 14.6 0.0 0.039 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Ysc84 PF04366.12 KND87415.1 - 2.6e-44 150.1 0.0 5.4e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Radical_SAM_C PF16199.5 KND87416.1 - 1.3e-31 108.5 0.0 2.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KND87416.1 - 6.5e-17 62.4 0.3 2.8e-16 60.3 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KND87416.1 - 2.3e-09 37.5 0.1 4.3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND87416.1 - 4.9e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND87416.1 - 0.027 14.9 0.1 0.061 13.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_28 PF00295.17 KND87417.1 - 1.2e-32 113.3 0.7 2.3e-32 112.3 0.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KND87417.1 - 0.0092 15.8 8.5 0.019 14.8 6.0 2.3 1 1 1 2 2 2 1 Right handed beta helix region MUG113 PF13455.6 KND87418.1 - 2e-22 79.6 0.1 5.5e-22 78.2 0.1 1.8 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KND87418.1 - 9e-22 77.6 0.1 6.7e-21 74.8 0.0 2.3 2 0 0 2 2 2 1 T5orf172 domain Sugar_tr PF00083.24 KND87419.1 - 1.1e-111 373.9 15.5 1.3e-111 373.6 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87419.1 - 1.4e-29 103.2 35.1 6.3e-27 94.4 25.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KND87419.1 - 0.00041 18.9 2.1 0.00049 18.6 0.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KND87419.1 - 0.0034 16.0 20.0 0.018 13.6 1.1 3.3 4 0 0 4 4 4 2 MFS/sugar transport protein DUF554 PF04474.12 KND87419.1 - 0.43 10.0 11.4 0.018 14.5 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF554) APH PF01636.23 KND87421.1 - 1.4e-12 48.1 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aa_trans PF01490.18 KND87422.1 - 4.4e-20 71.8 29.7 8.5e-20 70.8 29.7 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF996 PF06195.13 KND87422.1 - 0.0055 17.0 4.1 0.0055 17.0 4.1 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF996) Fungal_trans PF04082.18 KND87423.1 - 7.5e-18 64.5 0.0 1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87423.1 - 1.1e-08 35.1 8.6 2.2e-08 34.1 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 KND87425.1 - 1.2e-24 87.2 0.8 1.5e-24 86.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87425.1 - 2.1e-17 63.3 0.4 2.7e-17 62.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND87425.1 - 3e-05 24.0 0.9 4.6e-05 23.4 0.9 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KND87425.1 - 0.0011 18.9 0.9 0.0035 17.3 1.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 KND87425.1 - 0.0089 15.4 0.3 0.02 14.2 0.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KND87425.1 - 0.036 13.8 0.3 0.095 12.5 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AXE1 PF05448.12 KND87425.1 - 0.2 10.3 0.1 0.3 9.7 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 KND87426.1 - 2.1e-14 53.2 0.2 5.3e-14 51.9 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KND87427.1 - 1.2e-87 294.7 23.3 1.4e-87 294.4 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87427.1 - 8.7e-19 67.6 27.6 8.7e-19 67.6 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CLP_protease PF00574.23 KND87430.1 - 3.3e-69 232.4 0.2 4.4e-69 232.0 0.2 1.1 1 0 0 1 1 1 1 Clp protease DUF2368 PF10166.9 KND87430.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) DUF5005 PF16396.5 KND87430.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) ILVD_EDD PF00920.21 KND87431.1 - 1.9e-212 706.5 0.4 2.2e-212 706.3 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Acyltransferase PF01553.21 KND87432.1 - 1.9e-05 24.3 0.0 4.6e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Kinesin PF00225.23 KND87433.1 - 1.5e-105 352.9 0.4 1.5e-105 352.9 0.4 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND87433.1 - 2.5e-56 189.7 0.0 6.5e-56 188.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KND87433.1 - 2.1e-05 23.5 36.0 2.1e-05 23.5 36.0 2.2 2 1 0 2 2 2 1 Weak chloroplast movement under blue light AAA_16 PF13191.6 KND87433.1 - 0.077 13.4 0.0 0.077 13.4 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain EzrA PF06160.12 KND87433.1 - 0.084 11.0 30.4 0.024 12.8 4.0 2.3 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KND87433.1 - 0.2 11.8 29.6 1.7 8.8 11.6 3.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc42p PF11544.8 KND87433.1 - 1.6 8.8 8.6 0.12 12.4 1.4 3.0 2 1 1 3 3 3 0 Spindle pole body component Spc42p OmpH PF03938.14 KND87433.1 - 2.9 8.2 36.7 7.1 7.0 4.8 3.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KND87433.1 - 3.6 6.8 34.7 55 3.0 22.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 KND87433.1 - 4 7.3 47.0 0.26 11.1 33.1 2.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3584 PF12128.8 KND87433.1 - 4.4 4.7 42.9 8.4 3.8 42.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 KND87433.1 - 5.3 7.1 11.2 74 3.4 5.9 3.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ACR_tran PF00873.19 KND87433.1 - 7.7 4.0 5.1 13 3.3 5.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family YtxH PF12732.7 KND87433.1 - 8.2 7.0 7.8 10 6.8 0.3 3.5 1 1 1 2 2 2 0 YtxH-like protein p450 PF00067.22 KND87434.1 - 6.1e-15 54.9 0.0 6.8e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 7tm_3 PF00003.22 KND87434.1 - 0.06 13.1 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF782 PF05614.11 KND87434.1 - 0.067 13.6 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) Flu_M1 PF00598.19 KND87434.1 - 0.15 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) p450 PF00067.22 KND87435.1 - 6.8e-51 173.4 0.0 8.1e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_12 PF13087.6 KND87436.1 - 1.9e-34 119.0 0.0 4.3e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KND87436.1 - 1.6e-18 67.5 0.0 4.2e-18 66.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND87436.1 - 1.2e-05 25.7 0.0 7.8e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Torus PF16131.5 KND87436.1 - 2.2e-05 25.1 0.1 6.6e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 Torus domain DUF2075 PF09848.9 KND87436.1 - 7.5e-05 22.1 0.1 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH_4 PF18044.1 KND87436.1 - 0.00011 21.9 4.8 0.00038 20.2 4.8 2.0 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_30 PF13604.6 KND87436.1 - 0.00024 20.9 0.2 0.055 13.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain zf_CCCH_4 PF18345.1 KND87436.1 - 0.00024 21.0 7.3 0.00061 19.8 7.3 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KND87436.1 - 0.00038 20.3 4.7 0.00093 19.0 4.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NTP_transf_3 PF12804.7 KND87436.1 - 0.0028 18.0 2.5 0.046 14.1 0.4 3.5 3 0 0 3 3 3 1 MobA-like NTP transferase domain UvrD_C_2 PF13538.6 KND87436.1 - 0.014 15.2 0.8 0.027 14.3 0.0 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Amino_oxidase PF01593.24 KND87437.1 - 2.6e-48 165.5 0.1 2.9e-48 165.3 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SGL PF08450.12 KND87438.1 - 3.1e-09 36.8 0.0 3.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region AA_permease_2 PF13520.6 KND87439.1 - 4.2e-25 88.5 26.5 7.9e-13 48.0 14.0 2.0 1 1 1 2 2 2 2 Amino acid permease Amino_oxidase PF01593.24 KND87440.1 - 1.6e-05 24.4 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND87440.1 - 0.0082 16.4 0.1 0.03 14.5 0.0 1.8 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain CBM9_2 PF16011.5 KND87441.1 - 1.3e-05 25.0 0.1 2.2e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 AMP-binding PF00501.28 KND87442.1 - 2.9e-46 157.9 0.0 4.3e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND87442.1 - 1.4e-09 38.8 0.0 2.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain P4Ha_N PF08336.11 KND87443.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Aldedh PF00171.22 KND87444.1 - 1.2e-139 465.8 0.0 1.4e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KND87444.1 - 0.0056 15.8 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) HAUS4 PF14735.6 KND87444.1 - 0.13 12.0 0.0 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 MAM33 PF02330.16 KND87445.1 - 7.1e-75 251.6 3.3 1.2e-74 250.8 3.3 1.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein Oxysterol_BP PF01237.18 KND87446.1 - 6.4e-49 166.8 0.0 1.1e-37 129.7 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Imm27 PF15590.6 KND87446.1 - 0.11 12.2 0.1 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 27 AAA PF00004.29 KND87447.1 - 7.1e-41 139.7 0.0 1.2e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND87447.1 - 3e-11 42.9 0.4 5.6e-11 42.1 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KND87447.1 - 7e-11 41.9 0.1 1.6e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 KND87447.1 - 5.7e-06 26.6 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KND87447.1 - 1e-05 25.8 0.1 0.0076 16.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KND87447.1 - 1.7e-05 24.1 0.0 2.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KND87447.1 - 0.00023 21.2 0.1 0.00079 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND87447.1 - 0.00052 20.4 0.1 0.0083 16.5 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KND87447.1 - 0.00054 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KND87447.1 - 0.0031 18.0 0.0 0.0064 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KND87447.1 - 0.0037 17.5 0.2 0.011 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KND87447.1 - 0.01 15.5 0.2 0.075 12.7 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 KND87447.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KND87447.1 - 0.02 14.1 0.0 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KND87447.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KND87447.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KND87447.1 - 0.029 13.8 1.7 0.56 9.6 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KND87447.1 - 0.035 14.2 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KND87447.1 - 0.064 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KND87447.1 - 0.069 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KND87447.1 - 0.082 12.8 0.1 0.7 9.8 0.1 2.3 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 KND87447.1 - 0.099 12.0 0.0 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 KND87447.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KND87447.1 - 0.12 12.0 0.3 0.38 10.5 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KND87447.1 - 0.19 11.3 2.1 0.63 9.6 0.4 2.5 2 1 0 3 3 3 0 AAA domain Promethin PF16015.5 KND87448.1 - 1.2e-32 112.0 15.6 1.4e-32 111.7 15.6 1.1 1 0 0 1 1 1 1 Promethin VIT1 PF01988.19 KND87448.1 - 0.37 10.6 6.1 0.45 10.3 6.1 1.2 1 0 0 1 1 1 0 VIT family Amidohydro_1 PF01979.20 KND87450.1 - 7.5e-42 143.9 0.0 1.1e-41 143.3 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family p450 PF00067.22 KND87450.1 - 2e-38 132.4 0.0 3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_3 PF07969.11 KND87450.1 - 9.9e-12 45.1 3.8 1.7e-05 24.5 0.7 3.0 2 1 0 2 2 2 2 Amidohydrolase family NICE-3 PF07406.11 KND87450.1 - 0.1 12.6 0.1 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 NICE-3 protein Mito_carr PF00153.27 KND87451.1 - 1.3e-14 53.8 0.0 1e-08 35.0 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein Methyltransf_25 PF13649.6 KND87452.1 - 1.9e-13 50.9 0.0 4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87452.1 - 4.3e-09 36.4 0.0 7.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87452.1 - 3.1e-08 34.2 0.0 6.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87452.1 - 1.3e-06 29.0 0.0 3.8e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87452.1 - 8.9e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KND87452.1 - 0.011 15.3 0.0 0.085 12.3 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KND87452.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 KND87452.1 - 0.036 15.1 0.0 0.12 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KND87452.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Complex1_LYR_2 PF13233.6 KND87453.1 - 0.0068 17.1 0.0 0.0079 16.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KND87453.1 - 0.014 15.4 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DNA_pol_phi PF04931.13 KND87454.1 - 4.2 5.3 7.0 6 4.8 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Exo_endo_phos PF03372.23 KND87455.1 - 2.7e-17 63.1 0.0 2.9e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KND87455.1 - 3.7e-09 36.2 6.7 1.3e-06 28.1 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KND87455.1 - 3.1e-08 33.8 3.1 4.2e-05 23.8 0.8 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KND87455.1 - 2 9.3 5.7 19 6.3 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich Repeat TFIIA PF03153.13 KND87455.1 - 6 6.7 10.1 8.7 6.2 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.23 KND87456.1 - 2.7e-17 63.1 0.0 2.9e-16 59.7 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KND87456.1 - 3.7e-09 36.2 6.7 1.3e-06 28.1 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KND87456.1 - 3.1e-08 33.8 3.1 4.2e-05 23.8 0.8 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KND87456.1 - 2 9.3 5.7 19 6.3 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich Repeat TFIIA PF03153.13 KND87456.1 - 6 6.7 10.1 8.7 6.2 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAI16-like PF10257.9 KND87458.1 - 8.1e-74 248.6 0.8 1.2e-73 248.1 0.8 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Mito_carr PF00153.27 KND87460.1 - 1.2e-34 118.0 0.7 7.3e-15 54.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND87460.1 - 0.00067 18.9 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Gammaproteobacterial serine protease 2-Hacid_dh_C PF02826.19 KND87462.1 - 4.6e-49 166.2 0.0 6.6e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND87462.1 - 1.5e-17 63.5 0.0 1.9e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND87462.1 - 0.015 15.5 0.0 0.036 14.2 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cu-oxidase PF00394.22 KND87463.1 - 3.7e-31 108.4 0.0 9.5e-30 103.8 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KND87463.1 - 2.9e-26 91.8 1.3 1.1e-24 86.7 0.1 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND87463.1 - 9.2e-24 83.7 2.0 4.5e-22 78.3 0.9 3.0 2 1 0 2 2 2 1 Multicopper oxidase Methyltransf_23 PF13489.6 KND87465.1 - 2.1e-24 86.2 0.0 3.7e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87465.1 - 2.2e-10 41.1 0.0 7.8e-10 39.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87465.1 - 4.4e-08 33.8 0.0 5e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87465.1 - 3.3e-07 30.8 0.0 1.6e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87465.1 - 1.6e-05 24.7 0.0 0.00035 20.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND87465.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 KND87465.1 - 0.033 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 KND87465.1 - 0.054 12.8 0.0 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_16 PF10294.9 KND87465.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Ank_2 PF12796.7 KND87468.1 - 6.2e-36 122.9 5.0 2.5e-15 56.8 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87468.1 - 3.2e-29 100.9 1.5 1.2e-09 38.5 0.0 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KND87468.1 - 4.2e-29 99.7 12.8 2.7e-06 27.6 0.1 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KND87468.1 - 1.7e-28 98.3 9.3 2.2e-12 47.0 0.1 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87468.1 - 1.9e-28 95.3 7.3 1.3e-05 25.2 0.0 7.1 7 1 0 7 7 7 5 Ankyrin repeat DUF4988 PF16378.5 KND87468.1 - 0.0025 17.5 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function Sbt_1 PF05982.12 KND87468.1 - 0.1 11.9 0.1 11 5.2 0.0 2.1 2 0 0 2 2 2 0 Na+-dependent bicarbonate transporter superfamily APH PF01636.23 KND87469.1 - 8.1e-05 22.6 0.3 0.00016 21.7 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 KND87471.1 - 0.0022 17.1 0.2 0.0059 15.7 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87471.1 - 0.096 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF89 PF01937.19 KND87472.1 - 2.9e-128 427.8 0.0 3.3e-128 427.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sulfotransfer_4 PF17784.1 KND87473.1 - 5.6e-59 199.6 0.0 6.4e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KND87473.1 - 0.00029 21.3 0.2 0.0012 19.3 0.1 1.9 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 KND87473.1 - 0.036 13.6 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase domain AA_permease PF00324.21 KND87474.1 - 6.8e-127 424.0 37.8 8e-127 423.7 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND87474.1 - 5.1e-38 131.0 45.3 6.6e-38 130.6 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KND87474.1 - 8.6 7.1 21.0 0.06 14.1 1.0 4.7 4 0 0 4 4 4 0 PrgI family protein HhH-GPD PF00730.25 KND87476.1 - 6.6e-05 23.3 0.0 0.00025 21.5 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KND87476.1 - 0.0074 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif GMC_oxred_N PF00732.19 KND87477.1 - 2.3e-65 220.9 0.0 3e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND87477.1 - 1.1e-14 55.1 0.0 2.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KND87477.1 - 8.9e-05 22.6 0.1 0.00047 20.3 0.0 2.4 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KND87477.1 - 0.00042 19.5 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KND87477.1 - 0.00089 18.9 0.6 0.0031 17.1 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KND87477.1 - 0.0028 16.9 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KND87477.1 - 0.0064 16.5 0.0 0.022 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KND87477.1 - 0.024 13.7 0.1 0.05 12.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KND87477.1 - 0.048 12.9 0.2 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KND87478.1 - 1.6e-27 96.4 0.0 1.5e-26 93.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Sod_Fe_C PF02777.18 KND87480.1 - 1.5e-32 111.8 0.0 2.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KND87480.1 - 2.2e-31 108.1 1.3 4.6e-31 107.1 0.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DctQ PF04290.12 KND87480.1 - 0.038 13.9 0.2 0.073 13.0 0.2 1.4 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component XPG_I PF00867.18 KND87481.1 - 9e-24 83.7 0.0 2.2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 KND87481.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 KND87481.1 - 0.033 14.3 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat XPG_N PF00752.17 KND87481.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain DUF5343 PF17278.2 KND87481.1 - 0.16 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5343) IBR PF01485.21 KND87482.1 - 5.6e-22 77.7 44.8 7.4e-12 45.3 5.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KND87482.1 - 0.0012 18.7 4.9 0.0012 18.7 4.9 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND87482.1 - 0.0038 17.5 6.6 0.0038 17.5 6.6 4.5 3 1 1 4 4 4 1 Ring finger domain zf-RING_4 PF14570.6 KND87482.1 - 0.25 11.2 37.2 0.87 9.4 8.7 3.9 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KND87482.1 - 3.5 7.9 25.2 0.71 10.1 0.5 4.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Tma16 PF11176.8 KND87483.1 - 3.7e-45 153.4 0.1 4.4e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_N PF00752.17 KND87484.1 - 2e-09 37.8 0.0 2.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 XPG N-terminal domain FAM183 PF14886.6 KND87484.1 - 0.014 16.1 0.2 0.034 14.9 0.2 1.5 1 1 1 2 2 2 0 FAM183A and FAM183B related Acetyltransf_1 PF00583.25 KND87485.1 - 0.0021 18.3 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND87485.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND87485.1 - 0.1 12.6 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein TauD PF02668.16 KND87487.1 - 3.1e-23 82.9 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KND87487.1 - 0.0065 15.6 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 CsiD Redoxin PF08534.10 KND87488.1 - 4.2e-29 101.2 0.0 5.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KND87488.1 - 1.9e-07 31.1 0.0 2.6e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Ank_2 PF12796.7 KND87489.1 - 1.6e-14 54.3 0.1 2.1e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND87489.1 - 7.1e-11 41.4 1.4 2e-05 24.6 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KND87489.1 - 1.3e-10 41.3 0.2 3.9e-06 27.0 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 KND87489.1 - 5.3e-10 39.6 0.2 5.6e-07 30.0 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND87489.1 - 3.9e-06 27.0 1.1 0.00037 20.7 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) APH PF01636.23 KND87491.1 - 3.5e-10 40.2 0.0 4.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87491.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KND87491.1 - 0.041 13.5 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family He_PIG PF05345.12 KND87491.1 - 0.083 13.1 0.0 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Putative Ig domain DUF1679 PF07914.11 KND87491.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) FOXP-CC PF16159.5 KND87492.1 - 0.59 10.8 4.0 0.68 10.6 0.7 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KND87492.1 - 2.6 8.7 12.8 2.9 8.5 0.4 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type RINGv PF12906.7 KND87493.1 - 0.00021 21.3 8.3 0.00038 20.5 8.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KND87493.1 - 0.0068 16.7 10.7 0.015 15.6 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KND87493.1 - 0.11 12.7 5.7 0.21 11.8 5.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KND87493.1 - 2.4 8.0 8.8 4.1 7.3 8.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 KND87493.1 - 7.5 6.5 8.2 14 5.7 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans PF04082.18 KND87494.1 - 2.7e-15 56.1 0.1 5.2e-15 55.2 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KND87495.1 - 2.6e-79 265.5 46.4 4.1e-43 147.3 21.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KND87495.1 - 7.9e-38 130.1 0.0 1.8e-17 64.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KND87495.1 - 3.5e-26 90.9 7.4 4.8e-25 87.3 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KND87495.1 - 5e-08 33.5 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KND87495.1 - 2.1e-07 30.4 34.7 8.4e-05 21.8 14.3 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KND87495.1 - 7.5e-06 26.4 0.4 0.0054 17.1 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND87495.1 - 7.2e-05 22.8 0.1 0.0064 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KND87495.1 - 0.00075 19.2 0.1 0.15 11.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KND87495.1 - 0.015 14.8 0.1 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KND87495.1 - 0.016 15.4 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KND87495.1 - 0.059 12.9 0.6 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KND87495.1 - 0.11 13.0 0.0 11 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KND87495.1 - 0.18 12.1 0.0 14 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KND87495.1 - 0.45 10.7 1.3 18 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Med3 PF11593.8 KND87496.1 - 5.2 6.2 7.1 0.2 10.8 0.5 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1525 PF07511.11 KND87497.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) AtuA PF07287.11 KND87498.1 - 5.4e-119 397.0 0.0 7.5e-119 396.5 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA zf-C2H2 PF00096.26 KND87499.1 - 0.49 11.0 8.2 8 7.1 1.5 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ion_trans_N PF08412.10 KND87501.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal Cutinase PF01083.22 KND87502.1 - 5.1e-41 140.6 5.9 5.1e-41 140.6 5.9 1.5 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.11 KND87502.1 - 3.4e-07 30.1 2.0 1.1e-06 28.4 0.3 2.3 1 1 1 2 2 2 1 PE-PPE domain Lipase_2 PF01674.18 KND87502.1 - 0.1 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) FTA2 PF13095.6 KND87503.1 - 0.0035 17.0 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 SRI PF08236.11 KND87503.1 - 0.025 14.7 0.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DNA_pol_B_palm PF14792.6 KND87503.1 - 0.026 14.7 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm CoA_transf_3 PF02515.17 KND87504.1 - 7.7e-33 114.1 0.0 1e-32 113.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III MFS_1 PF07690.16 KND87505.1 - 2.8e-33 115.3 65.0 7e-32 110.7 65.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4366 PF14283.6 KND87506.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.11 KND87506.1 - 0.1 12.0 1.4 0.13 11.7 1.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.9 KND87506.1 - 0.16 10.8 7.2 0.18 10.6 7.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KND87506.1 - 0.21 10.3 0.2 0.34 9.6 0.2 1.3 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 KND87506.1 - 0.22 11.4 10.4 0.26 11.1 10.4 1.1 1 0 0 1 1 1 0 SPX domain Menin PF05053.13 KND87506.1 - 6 5.1 6.7 7.5 4.8 6.7 1.1 1 0 0 1 1 1 0 Menin Sulfotransfer_4 PF17784.1 KND87507.1 - 8.9e-71 238.1 0.0 1.1e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KND87507.1 - 0.00095 19.6 0.4 0.16 12.3 0.1 2.3 1 1 0 2 2 2 2 Sulfotransferase family GalKase_gal_bdg PF10509.9 KND87508.1 - 6.8e-21 73.6 0.3 1.5e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KND87508.1 - 8.9e-16 57.9 1.6 2.5e-15 56.4 1.6 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND87508.1 - 1.5e-14 54.2 0.0 4.7e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal CCDC74_C PF14917.6 KND87508.1 - 0.11 13.1 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Sigma70_r3 PF04539.16 KND87508.1 - 0.15 12.1 0.7 0.38 10.9 0.7 1.7 1 0 0 1 1 1 0 Sigma-70 region 3 ABC_tran PF00005.27 KND87509.1 - 2.2e-16 60.6 0.1 3.3e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND87509.1 - 0.00012 21.6 0.5 0.00038 20.0 0.5 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND87509.1 - 0.0099 15.7 0.8 2.5 7.8 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KND87509.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_membrane PF00664.23 KND87510.1 - 6e-12 45.8 1.6 7.4e-12 45.5 1.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Renin_r PF07850.14 KND87510.1 - 0.043 14.4 0.1 0.069 13.8 0.1 1.4 1 0 0 1 1 1 0 Renin receptor-like protein TMEM156 PF15106.6 KND87510.1 - 0.18 11.2 0.1 0.25 10.7 0.1 1.1 1 0 0 1 1 1 0 TMEM156 protein family Tad PF13400.6 KND87510.1 - 7.8 6.9 9.0 25 5.3 3.6 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like MIOX PF05153.15 KND87511.1 - 2.5e-122 407.2 0.1 2.5e-122 407.2 0.1 1.4 2 0 0 2 2 2 1 Myo-inositol oxygenase DUF4015 PF13200.6 KND87511.1 - 0.031 13.4 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain HD PF01966.22 KND87511.1 - 0.082 13.1 0.0 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 HD domain ABC_tran PF00005.27 KND87512.1 - 9.3e-33 113.6 0.0 5.2e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 KND87512.1 - 3.2e-20 72.9 8.3 6.6e-20 71.9 8.3 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KND87512.1 - 0.00021 20.8 0.0 0.0014 18.1 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 KND87512.1 - 0.00061 19.1 0.0 0.0016 17.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin PAM2 PF07145.15 KND87512.1 - 0.00086 18.8 0.0 0.0021 17.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RsgA_GTPase PF03193.16 KND87512.1 - 0.0035 17.3 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KND87512.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND87512.1 - 0.02 14.6 0.2 0.054 13.3 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 KND87512.1 - 0.032 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KND87512.1 - 0.13 11.9 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Coleoptericin PF06286.11 KND87512.1 - 0.15 12.1 0.8 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Coleoptericin MMR_HSR1 PF01926.23 KND87512.1 - 0.17 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2964 PF11177.8 KND87512.1 - 0.18 12.1 2.5 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) SGTA_dimer PF16546.5 KND87514.1 - 1.2e-25 89.1 0.5 2e-25 88.3 0.5 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KND87514.1 - 8.8e-15 53.8 5.3 1.3e-07 31.1 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND87514.1 - 3e-13 48.8 8.6 5.4e-06 26.1 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND87514.1 - 7.6e-10 38.3 2.2 8.7e-06 25.3 0.6 2.6 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KND87514.1 - 1.3e-09 38.5 16.3 1.4e-05 25.6 9.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND87514.1 - 4.5e-06 26.7 5.1 0.0038 17.5 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND87514.1 - 7.5e-06 26.4 5.2 0.0015 19.0 2.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND87514.1 - 2.8e-05 24.5 12.5 0.036 14.9 0.5 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND87514.1 - 3.6e-05 23.6 4.1 2.6 8.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND87514.1 - 0.00016 21.9 6.5 0.00023 21.4 2.9 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND87514.1 - 0.00028 20.7 1.2 0.02 14.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 KND87514.1 - 0.0023 17.8 7.5 0.0023 17.8 7.5 2.5 2 0 0 2 2 2 1 STI1 domain TPR_9 PF13371.6 KND87514.1 - 0.0043 17.2 0.9 0.0043 17.2 0.9 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat MIT PF04212.18 KND87514.1 - 0.13 12.4 2.4 1.6 8.9 0.6 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 KND87514.1 - 0.17 12.6 8.0 3.5 8.5 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat XPC-binding PF09280.11 KND87514.1 - 0.27 11.0 3.8 0.26 11.0 2.4 1.7 2 0 0 2 2 2 0 XPC-binding domain BTAD PF03704.17 KND87514.1 - 0.47 10.9 3.3 18 5.7 0.1 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KND87514.1 - 0.91 9.5 9.1 1.7 8.6 0.5 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Vps35 PF03635.17 KND87515.1 - 0 1021.5 0.0 0 1021.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Acetyltransf_10 PF13673.7 KND87516.1 - 1.3e-05 25.2 0.2 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND87516.1 - 1.7e-05 25.0 0.5 2.4e-05 24.5 0.5 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KND87516.1 - 0.02 15.0 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NST1 PF13945.6 KND87517.1 - 8.8e-50 169.5 6.2 8.8e-50 169.5 6.2 4.6 4 2 1 5 5 5 1 Salt tolerance down-regulator NARP1 PF12569.8 KND87518.1 - 6.9e-182 606.0 27.0 1e-179 598.8 20.5 2.4 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 KND87518.1 - 2.6e-22 79.1 23.3 0.00017 22.0 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KND87518.1 - 4.7e-17 62.4 23.7 0.0027 18.3 0.1 8.4 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KND87518.1 - 2.8e-15 55.7 20.4 0.0021 18.8 0.0 10.6 7 4 4 11 11 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND87518.1 - 1.2e-14 53.1 19.4 0.00017 21.4 0.3 9.9 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND87518.1 - 2.9e-11 42.7 17.8 2e-05 24.2 0.5 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND87518.1 - 2.8e-10 40.2 6.6 1.9e-05 24.7 0.4 6.3 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND87518.1 - 9.1e-10 38.1 9.3 1.9e-06 27.5 0.1 5.1 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 KND87518.1 - 1.4e-09 37.4 12.5 0.00078 19.5 0.2 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KND87518.1 - 1.5e-09 37.9 14.2 0.00028 21.1 0.4 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 KND87518.1 - 2.3e-07 30.7 9.4 0.4 11.2 0.0 7.8 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND87518.1 - 0.00074 19.8 24.7 0.0066 16.7 0.4 7.7 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 KND87518.1 - 0.0022 17.3 25.2 0.053 12.7 0.7 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_3 PF07720.12 KND87518.1 - 0.027 14.5 0.9 0.81 9.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND87518.1 - 0.064 13.2 12.9 1.4 8.9 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1758 PF05585.12 KND87518.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF2205 PF10224.9 KND87518.1 - 0.085 12.9 1.0 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 Short coiled-coil protein TPR_7 PF13176.6 KND87518.1 - 0.42 10.8 10.6 75 3.7 0.0 7.1 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND87518.1 - 0.96 10.2 12.2 5.3 7.9 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND87518.1 - 1.7 8.7 11.8 18 5.5 0.1 5.7 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.9 KND87519.1 - 2e-53 181.1 0.1 2.4e-53 180.8 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DAGK_cat PF00781.24 KND87520.1 - 3.8e-25 87.9 0.0 5.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PerB PF06590.11 KND87520.1 - 0.12 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 PerB protein BCS1_N PF08740.11 KND87521.1 - 5.2e-41 140.7 0.0 7e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KND87521.1 - 4.1e-17 62.9 0.0 6.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KND87521.1 - 0.00054 19.5 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 KND87521.1 - 0.0008 19.0 0.0 0.011 15.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KND87521.1 - 0.0034 17.4 0.0 0.02 14.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND87521.1 - 0.0051 17.2 0.0 0.011 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KND87521.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KND87521.1 - 0.0066 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KND87521.1 - 0.0098 16.4 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 KND87521.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 KND87521.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KND87521.1 - 0.031 14.5 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KND87521.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KND87521.1 - 0.037 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND87521.1 - 0.074 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PPV_E1_C PF00519.17 KND87521.1 - 0.084 11.7 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Papillomavirus helicase NACHT PF05729.12 KND87521.1 - 0.1 12.5 0.1 3.3 7.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 KND87521.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KND87521.1 - 0.15 12.5 0.0 0.65 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KND87521.1 - 0.15 11.8 0.0 0.44 10.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2263 PF10021.9 KND87522.1 - 8.8e-23 81.3 0.0 1.7e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Oxysterol_BP PF01237.18 KND87523.1 - 7.6e-64 215.9 0.5 1.1e-61 208.8 0.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1579 PF07617.11 KND87523.1 - 0.022 14.7 0.1 1 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1579) F_bP_aldolase PF01116.20 KND87524.1 - 4.9e-90 301.8 0.0 5.9e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p47_phox_C PF08944.11 KND87524.1 - 0.15 11.5 0.7 0.37 10.2 0.7 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain BTB PF00651.31 KND87525.1 - 3.8e-06 27.1 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Amidohydro_1 PF01979.20 KND87526.1 - 2.4e-54 184.9 0.1 3.3e-54 184.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND87526.1 - 3.9e-09 36.5 2.0 4.8e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KND87526.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase BOP1NT PF08145.12 KND87529.1 - 6e-105 350.9 2.9 9.9e-105 350.1 2.9 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KND87529.1 - 4.8e-26 90.5 4.0 8.7e-13 48.5 0.2 5.8 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87529.1 - 3.4e-06 27.3 0.1 0.02 15.2 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND87529.1 - 0.22 10.5 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BUD22 PF09073.10 KND87529.1 - 1.2 8.4 9.3 2.3 7.5 9.3 1.3 1 0 0 1 1 1 0 BUD22 Ish1 PF10281.9 KND87530.1 - 2.5e-86 283.7 15.4 1.4e-13 50.9 0.1 8.9 9 0 0 9 9 9 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KND87530.1 - 2.6e-11 43.0 0.0 0.23 11.3 0.0 7.3 8 0 0 8 8 8 3 SAP domain Slx4 PF09494.10 KND87530.1 - 7.3e-07 29.0 0.4 8.4 6.4 0.0 6.2 7 0 0 7 7 7 2 Slx4 endonuclease HeH PF12949.7 KND87530.1 - 4.1e-05 23.2 0.0 1.6 8.5 0.0 5.4 5 0 0 5 5 5 1 HeH/LEM domain DUF3612 PF12268.8 KND87530.1 - 0.0077 16.4 0.2 21 5.2 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3612) TPD PF14811.6 KND87530.1 - 0.028 14.3 0.0 5.5 6.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function TPD sequence-motif Lipase3_N PF03893.16 KND87530.1 - 0.045 13.8 0.5 0.16 12.0 0.5 1.9 1 0 0 1 1 1 0 Lipase 3 N-terminal region EF-hand_9 PF14658.6 KND87530.1 - 0.15 12.4 0.0 43 4.5 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain ArfGap PF01412.18 KND87530.1 - 3.7 7.6 6.8 23 5.1 0.9 3.7 2 2 1 3 3 3 0 Putative GTPase activating protein for Arf AAA PF00004.29 KND87531.1 - 1.1e-39 135.9 0.0 2.2e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KND87531.1 - 3.6e-17 62.0 0.1 7.1e-17 61.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KND87531.1 - 5.2e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KND87531.1 - 0.00017 21.6 0.1 0.00079 19.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KND87531.1 - 0.00055 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND87531.1 - 0.0007 20.0 1.5 0.096 13.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KND87531.1 - 0.0011 19.2 0.8 0.11 12.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.14 KND87531.1 - 0.0015 18.7 0.1 0.01 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KND87531.1 - 0.01 15.3 0.2 0.13 11.7 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 KND87531.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KND87531.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KND87531.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ribosomal_L10 PF00466.20 KND87532.1 - 0.0032 17.6 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 CSN8_PSD8_EIF3K PF10075.9 KND87534.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family RecQ_Zn_bind PF16124.5 KND87534.1 - 0.017 15.9 0.0 0.032 14.9 0.0 1.5 1 0 0 1 1 1 0 RecQ zinc-binding MRP-L28 PF09812.9 KND87535.1 - 0.0031 17.7 0.0 0.0037 17.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 AGTRAP PF06396.11 KND87536.1 - 0.081 12.7 1.1 0.15 11.9 1.1 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) SLATT_5 PF18160.1 KND87536.1 - 0.14 11.5 0.6 0.29 10.4 0.6 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 AMP-binding PF00501.28 KND87537.1 - 1.3e-86 290.9 0.3 2.9e-49 167.8 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 KND87537.1 - 1.9e-23 82.6 0.1 5.9e-11 42.6 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site MFS_1 PF07690.16 KND87539.1 - 2.8e-10 39.7 14.1 2.8e-10 39.7 14.1 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily CBP_BcsF PF11120.8 KND87539.1 - 0.94 9.6 2.9 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF Arylsulfotran_2 PF14269.6 KND87540.1 - 9.8e-47 159.8 0.0 1.4e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KND87540.1 - 7.8e-25 87.6 0.2 2.3e-24 86.0 0.2 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Ank_4 PF13637.6 KND87541.1 - 5.5e-30 103.4 0.5 3.3e-14 53.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87541.1 - 7.4e-26 90.6 0.2 4.7e-14 52.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KND87541.1 - 3e-25 87.5 1.7 4.9e-06 26.7 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 KND87541.1 - 3.9e-22 76.0 0.1 1.9e-05 24.7 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KND87541.1 - 8.6e-17 61.0 2.3 2.3e-08 34.1 0.2 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KND87541.1 - 0.014 15.3 3.1 0.75 9.7 0.0 3.0 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain Cyclase PF04199.13 KND87543.1 - 8.1e-18 65.0 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 KND87544.1 - 2.8e-86 290.2 22.9 3.2e-86 290.0 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87544.1 - 4e-29 101.6 36.1 8.4e-22 77.6 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 KND87545.1 - 4.4e-08 33.9 0.1 6.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND87545.1 - 1.5e-05 25.2 0.0 0.00021 21.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lipase_GDSL_2 PF13472.6 KND87545.1 - 0.055 13.9 0.0 0.072 13.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4470 PF14737.6 KND87546.1 - 2.8e-24 85.1 0.0 5.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KND87546.1 - 9.1e-08 32.1 9.6 1.6e-07 31.3 9.6 1.4 1 0 0 1 1 1 1 MYND finger DNA_pol3_delta2 PF13177.6 KND87546.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit zf-C6H2 PF15801.5 KND87546.1 - 0.17 12.2 6.6 0.3 11.4 6.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Cauli_AT PF03233.13 KND87546.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein adh_short_C2 PF13561.6 KND87547.1 - 1.6e-05 24.6 0.0 0.005 16.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87547.1 - 0.00041 19.8 0.0 0.00097 18.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 KND87547.1 - 0.003 17.1 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND87547.1 - 0.011 14.8 0.1 0.023 13.8 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain 3HCDH_N PF02737.18 KND87547.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPP_enzyme_N PF02776.18 KND87548.1 - 3.4e-56 189.5 0.0 1.9e-54 183.9 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KND87548.1 - 5.9e-49 165.8 0.1 3.3e-47 160.1 0.1 2.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND87548.1 - 1.5e-40 138.1 0.6 5.1e-40 136.4 0.6 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain VPS9 PF02204.18 KND87549.1 - 4.8e-18 65.3 0.0 1.4e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 KND87549.1 - 7.5e-16 58.0 0.2 6.9e-14 51.7 0.1 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87549.1 - 3.2e-11 43.7 0.0 0.0029 18.2 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND87549.1 - 7.8e-05 23.1 0.2 0.023 15.3 0.0 4.1 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87549.1 - 7.9e-05 22.8 0.8 0.29 11.8 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.24 KND87549.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Ank PF00023.30 KND87549.1 - 0.035 14.6 0.1 25 5.5 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Laminin_II PF06009.12 KND87549.1 - 0.24 11.4 1.9 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II AA_permease PF00324.21 KND87550.1 - 1.5e-105 353.6 35.4 1.7e-105 353.4 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND87550.1 - 1.1e-23 83.7 39.5 1.5e-23 83.3 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_C97 PF05903.14 KND87551.1 - 1.8e-35 122.0 0.0 2.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KND87551.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.19 KND87552.1 - 5.6e-08 33.2 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 YchF-GTPase_C PF06071.13 KND87553.1 - 9.6e-34 115.4 0.2 2.5e-33 114.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KND87553.1 - 1.7e-15 57.1 0.0 4e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND87553.1 - 0.00079 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 KND87553.1 - 0.006 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain PPAK PF02818.15 KND87553.1 - 0.016 15.4 1.1 0.053 13.7 1.1 1.9 1 0 0 1 1 1 0 PPAK motif AKAP95 PF04988.12 KND87553.1 - 0.17 12.1 0.2 0.31 11.3 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DNA_pol3_a_NII PF11490.8 KND87553.1 - 1 9.3 5.5 3.8 7.4 0.1 2.9 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus II AAA_23 PF13476.6 KND87553.1 - 5.1 7.5 6.3 1e+02 3.3 6.3 2.3 1 1 0 1 1 1 0 AAA domain TFR_dimer PF04253.15 KND87555.1 - 3.8e-33 114.2 0.0 6.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KND87555.1 - 2e-23 83.1 0.0 1.3e-22 80.5 0.0 2.3 3 0 0 3 3 3 1 Peptidase family M28 PA PF02225.22 KND87555.1 - 5.1e-14 52.1 0.1 1e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KND87555.1 - 0.034 13.8 0.0 0.13 11.9 0.0 1.7 1 1 0 2 2 2 0 Peptidase family M20/M25/M40 EF-1_beta_acid PF10587.9 KND87555.1 - 0.27 11.7 1.4 0.7 10.4 1.4 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Cyt-b5 PF00173.28 KND87556.1 - 2.2e-11 43.8 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1768 PF08719.11 KND87557.1 - 4.4e-56 189.6 0.0 5e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.15 KND87558.1 - 2.5e-32 112.0 0.1 2.1e-31 109.0 0.0 2.2 2 0 0 2 2 2 1 Tim44-like domain SURF2 PF05477.11 KND87558.1 - 0.047 13.4 13.2 0.1 12.3 13.2 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DHHW PF14286.6 KND87558.1 - 2.9 7.1 9.2 0.85 8.9 2.4 2.6 3 0 0 3 3 3 0 DHHW protein Med7 PF05983.11 KND87558.1 - 6.9 6.7 7.0 10 6.2 5.9 1.8 1 1 1 2 2 2 0 MED7 protein UPF0020 PF01170.18 KND87559.1 - 3.1e-07 30.3 0.0 0.016 14.9 0.0 2.3 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Ribonuc_P_40 PF08584.11 KND87560.1 - 1.3e-60 205.1 0.0 2e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Mago_nashi PF02792.14 KND87561.1 - 3.5e-71 237.9 0.4 3.9e-71 237.7 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 KND87562.1 - 4.3e-64 215.2 0.7 5.3e-64 214.9 0.7 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein PM0188 PF11477.8 KND87562.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 UBD PF16455.5 KND87563.1 - 1e-39 135.0 0.0 1.6e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KND87563.1 - 1.8e-06 27.6 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KND87563.1 - 1.6e-05 24.6 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF4141 PF13605.6 KND87563.1 - 0.00065 18.9 0.1 0.0021 17.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) DUF2407 PF10302.9 KND87563.1 - 0.043 14.4 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KND87563.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ank_5 PF13857.6 KND87566.1 - 2.7e-09 37.1 0.1 1.9e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND87566.1 - 0.00011 22.3 0.3 0.0013 19.0 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KND87566.1 - 0.00047 20.7 0.0 0.01 16.4 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87566.1 - 0.00081 19.9 0.1 0.0039 17.7 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KND87566.1 - 0.13 12.8 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat tRNA_lig_CPD PF08302.11 KND87567.1 - 5.4e-87 291.4 0.0 7.2e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KND87567.1 - 1.7e-84 283.1 0.0 2.7e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KND87567.1 - 4e-53 180.0 0.0 7.9e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain ABC_tran PF00005.27 KND87567.1 - 0.072 13.6 0.2 0.34 11.4 0.0 2.2 3 0 0 3 3 3 0 ABC transporter FKBP_N PF01346.18 KND87568.1 - 0.023 15.6 0.0 0.092 13.7 0.0 2.0 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DAGK_cat PF00781.24 KND87569.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Fis1_TPR_C PF14853.6 KND87569.1 - 0.17 12.0 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.22 KND87571.1 - 9.1e-46 155.4 0.0 1.1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND87571.1 - 1.2e-19 70.6 0.0 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND87571.1 - 6.8e-06 25.6 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KND87571.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KND87571.1 - 0.083 12.6 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KND87571.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND87571.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 KND87571.1 - 0.23 11.2 0.1 0.43 10.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sugar_tr PF00083.24 KND87572.1 - 7.7e-26 90.9 36.1 1.7e-13 50.2 12.5 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KND87572.1 - 3.4e-11 42.7 53.4 2.2e-05 23.6 21.0 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.8 KND87572.1 - 8.7 6.7 11.8 0.57 10.5 0.6 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) UEV PF05743.13 KND87573.1 - 2.8e-36 124.0 0.0 4.4e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KND87573.1 - 1.3e-22 79.5 0.0 8e-22 77.0 0.0 2.2 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 KND87573.1 - 0.0026 17.4 0.2 0.0056 16.3 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Mce4_CUP1 PF11887.8 KND87573.1 - 0.081 12.4 1.0 0.12 11.8 0.4 1.6 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Spidroin_N PF16763.5 KND87573.1 - 0.13 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Gp37 PF09646.10 KND87573.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Gp37 protein Bacillus_HBL PF05791.11 KND87573.1 - 0.18 11.6 0.1 0.29 10.9 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) STE2 PF02116.15 KND87574.1 - 1.2e-88 297.1 15.6 1.4e-88 296.9 15.6 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Spem1 PF15670.5 KND87574.1 - 0.04 13.5 1.4 0.064 12.8 1.4 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 PalH PF08733.10 KND87574.1 - 0.25 10.3 12.9 0.36 9.8 12.9 1.1 1 0 0 1 1 1 0 PalH/RIM21 RNA_pol_Rpb2_6 PF00562.28 KND87575.1 - 1.6e-125 419.3 0.5 2.7e-125 418.5 0.3 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KND87575.1 - 4.7e-51 173.2 0.0 1.1e-50 172.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KND87575.1 - 1.4e-45 155.3 0.0 2.7e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KND87575.1 - 2.5e-33 114.3 0.1 6.7e-33 113.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 KND87575.1 - 2.1e-25 88.7 0.1 4.9e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KND87575.1 - 1.7e-23 82.9 0.2 4.9e-23 81.4 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 KND87575.1 - 5.3e-18 65.1 0.2 1.6e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 IDO PF01231.18 KND87576.1 - 1.3e-164 548.1 0.0 1.5e-164 547.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase V-ATPase_G PF03179.15 KND87577.1 - 5.3e-30 104.1 12.5 6.3e-30 103.8 12.5 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 KND87577.1 - 0.037 14.4 14.1 0.055 13.9 13.9 1.4 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KND87577.1 - 0.31 10.4 16.0 0.16 11.4 12.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) RRF PF01765.19 KND87577.1 - 0.34 10.8 8.4 0.48 10.4 8.4 1.4 1 0 0 1 1 1 0 Ribosome recycling factor ATP-synt_B PF00430.18 KND87577.1 - 1.6 8.9 20.5 0.089 12.9 10.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4666 PF15697.5 KND87577.1 - 1.6 9.4 6.6 5.2 7.8 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) Seryl_tRNA_N PF02403.22 KND87577.1 - 6.6 7.0 11.4 14 6.0 11.4 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PET117 PF15786.5 KND87578.1 - 1.9e-24 85.7 3.1 2.2e-24 85.5 3.1 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF2721 PF11026.8 KND87578.1 - 0.63 9.9 2.3 1.1 9.2 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) MFS_1 PF07690.16 KND87579.1 - 1.3e-30 106.6 50.8 3.9e-30 105.0 50.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND87579.1 - 3.7e-06 25.7 21.9 3.7e-06 25.7 21.9 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Spore_III_AF PF09581.10 KND87579.1 - 0.16 12.0 3.3 0.073 13.1 0.9 1.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) M_domain PF12938.7 KND87579.1 - 0.17 11.7 2.0 0.49 10.1 0.3 2.0 2 0 0 2 2 2 0 M domain of GW182 MFS_1_like PF12832.7 KND87579.1 - 0.95 8.2 20.7 0.029 13.2 8.6 2.8 3 0 0 3 3 3 0 MFS_1 like family CTNNBL PF08216.11 KND87580.1 - 7.3e-37 125.7 0.0 2.2e-36 124.2 0.0 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear GTP_cyclohydro2 PF00925.20 KND87581.1 - 9.5e-61 204.1 0.0 1.3e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II OB_NTP_bind PF07717.16 KND87583.1 - 5.9e-22 77.8 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KND87583.1 - 1.5e-18 67.1 0.0 1.5e-18 67.1 0.0 3.6 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KND87583.1 - 3e-14 53.3 0.0 1.2e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND87583.1 - 1.5e-05 24.9 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND87583.1 - 2.6e-05 24.5 0.1 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KND87583.1 - 0.0013 17.9 0.6 0.0032 16.6 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KND87583.1 - 0.002 17.9 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KND87583.1 - 0.007 16.0 0.1 0.02 14.5 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain PhoH PF02562.16 KND87583.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 KND87583.1 - 0.36 11.3 0.0 0.36 11.3 0.0 2.3 3 1 1 4 4 3 0 ABC transporter AAA_14 PF13173.6 KND87583.1 - 0.47 10.5 2.3 2.7 8.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 KND87584.1 - 1.2e-09 39.0 0.2 1.7e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 KND87585.1 - 1.9e-06 28.0 0.1 2e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87585.1 - 0.11 12.1 0.3 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Nuc_deoxyri_tr3 PF11071.8 KND87587.1 - 0.074 13.1 0.1 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ AAA_12 PF13087.6 KND87588.1 - 4.6e-31 108.0 0.0 1e-30 106.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND87588.1 - 3.9e-25 89.1 0.0 3.9e-25 89.1 0.0 5.3 6 0 0 6 6 5 1 AAA domain AAA PF00004.29 KND87588.1 - 1.2e-21 77.5 0.0 2.8e-08 34.3 0.0 4.6 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND87588.1 - 4.3e-18 65.7 0.4 4.2e-07 29.9 0.0 4.8 4 1 0 4 4 4 4 AAA domain AAA_19 PF13245.6 KND87588.1 - 1.2e-16 61.4 0.0 1.6e-10 41.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_lid_6 PF17866.1 KND87588.1 - 6.3e-13 48.7 8.7 2.3e-06 27.7 1.0 4.2 3 0 0 3 3 3 2 AAA lid domain AAA_16 PF13191.6 KND87588.1 - 1.7e-10 41.6 0.3 0.045 14.1 0.1 4.3 3 0 0 3 3 3 3 AAA ATPase domain AAA_5 PF07728.14 KND87588.1 - 1.5e-08 34.8 0.5 0.1 12.6 0.0 4.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND87588.1 - 3.1e-08 34.0 2.7 0.077 13.3 0.1 5.2 4 1 0 5 5 4 2 AAA domain IstB_IS21 PF01695.17 KND87588.1 - 2.1e-05 24.3 0.0 1.2 8.8 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 KND87588.1 - 3.9e-05 23.4 0.2 4.1 7.1 0.0 4.3 3 1 1 4 4 4 1 Sigma-54 interaction domain RuvB_N PF05496.12 KND87588.1 - 5.7e-05 22.9 0.0 0.26 11.0 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KND87588.1 - 6.8e-05 22.3 0.0 1.7 8.0 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KND87588.1 - 9.8e-05 22.2 0.1 1.1 9.0 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 KND87588.1 - 0.00018 21.1 1.0 0.3 10.6 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KND87588.1 - 0.00038 21.0 5.1 8.5 6.9 0.1 4.7 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 KND87588.1 - 0.00041 19.9 0.1 1.4 8.4 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region ATPase PF06745.13 KND87588.1 - 0.0019 17.6 0.2 5 6.4 0.0 3.4 3 0 0 3 3 3 1 KaiC DUF2075 PF09848.9 KND87588.1 - 0.0028 17.0 0.0 0.0028 17.0 0.0 4.7 7 0 0 7 7 6 1 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 KND87588.1 - 0.0046 17.1 0.0 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Torsin PhoH PF02562.16 KND87588.1 - 0.005 16.3 0.2 7.2 6.0 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein RNA_helicase PF00910.22 KND87588.1 - 0.0064 16.9 0.2 35 4.9 0.0 3.6 3 0 0 3 3 3 0 RNA helicase ResIII PF04851.15 KND87588.1 - 0.0083 16.1 0.0 0.13 12.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 KND87588.1 - 0.012 15.6 0.2 3 7.7 0.0 3.8 4 0 0 4 4 4 0 RsgA GTPase AAA_29 PF13555.6 KND87588.1 - 0.017 14.9 0.2 17 5.2 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KND87588.1 - 0.074 13.2 9.8 6.5 6.9 0.0 4.5 4 0 0 4 4 3 0 AAA domain Helicase_RecD PF05127.14 KND87588.1 - 0.084 12.7 0.0 2.9 7.7 0.0 3.1 3 0 0 3 3 2 0 Helicase FeoB_N PF02421.18 KND87588.1 - 0.25 10.9 0.8 2.2 7.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B UvrD-helicase PF00580.21 KND87588.1 - 0.34 10.4 0.0 0.34 10.4 0.0 4.6 6 0 0 6 6 5 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 KND87588.1 - 1.7 8.5 3.4 50 3.7 0.1 3.5 4 0 0 4 4 4 0 NTPase ABC_tran PF00005.27 KND87588.1 - 2 8.9 7.1 26 5.3 0.1 4.0 4 0 0 4 4 4 0 ABC transporter zf-NF-X1 PF01422.17 KND87588.1 - 6.1 7.0 6.2 14 5.8 6.2 1.6 1 0 0 1 1 1 0 NF-X1 type zinc finger zf-FCS PF06467.14 KND87589.1 - 0.018 15.0 0.7 0.033 14.1 0.7 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Peptidase_C14 PF00656.22 KND87593.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KND87593.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.26 KND87593.1 - 0.098 13.2 26.3 0.067 13.7 2.0 4.9 4 2 0 4 4 4 0 Zinc finger, C2H2 type BCA_ABC_TP_C PF12399.8 KND87593.1 - 0.1 12.5 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Sina PF03145.16 KND87593.1 - 0.18 11.7 3.4 0.37 10.7 3.4 1.5 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_4 PF13894.6 KND87593.1 - 0.51 11.3 24.2 0.21 12.5 2.1 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND87593.1 - 1.5 9.2 4.3 17 5.9 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 KND87593.1 - 6 7.6 7.6 0.26 12.0 0.9 2.3 3 0 0 3 3 3 0 TRAF-type zinc finger AMP-binding PF00501.28 KND87595.1 - 5.9e-69 232.7 0.0 9.2e-67 225.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF658 PF04936.12 KND87595.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) MFS_1 PF07690.16 KND87596.1 - 3.3e-37 128.2 50.0 3.3e-37 128.2 50.0 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87596.1 - 1e-08 34.5 15.4 1e-08 34.5 15.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KND87596.1 - 0.27 9.5 20.0 0.11 10.7 16.1 2.3 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans_2 PF11951.8 KND87600.1 - 5.2e-10 38.7 0.2 7.6e-10 38.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA_C PF02894.17 KND87601.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.4 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain p450 PF00067.22 KND87602.1 - 1.5e-42 145.9 0.0 8.9e-40 136.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Patatin PF01734.22 KND87603.1 - 1.7e-06 28.4 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase AA_permease_2 PF13520.6 KND87604.1 - 4.2e-55 187.3 47.3 5.2e-55 187.0 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND87604.1 - 6.1e-32 110.8 45.3 7.3e-32 110.6 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease SLATT_5 PF18160.1 KND87604.1 - 4 6.7 5.9 0.84 8.9 1.3 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Amino_oxidase PF01593.24 KND87605.1 - 3.1e-47 161.9 0.1 3.7e-47 161.6 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND87605.1 - 5.7e-10 39.3 0.1 1.4e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND87605.1 - 3.1e-07 30.3 1.5 3.2e-06 27.0 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KND87605.1 - 7.1e-05 22.2 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KND87605.1 - 0.00045 19.7 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND87605.1 - 0.0032 16.8 0.0 0.024 13.9 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND87605.1 - 0.0044 15.8 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KND87605.1 - 0.0083 15.3 0.2 0.013 14.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KND87605.1 - 0.059 12.6 0.0 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND87605.1 - 0.12 11.4 0.2 0.21 10.6 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KND87605.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans_2 PF11951.8 KND87606.1 - 6.4e-23 81.2 4.5 2.9e-13 49.4 0.5 2.2 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87606.1 - 0.0013 18.9 15.8 0.0027 17.8 15.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 KND87607.1 - 2.5e-29 102.4 2.7 7.8e-29 100.8 2.7 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KND87607.1 - 1.5e-23 82.8 0.1 2.7e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fungal_trans PF04082.18 KND87607.1 - 4.6e-21 75.1 0.1 7.1e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_N PF02771.16 KND87607.1 - 2.5e-16 60.3 0.1 4e-11 43.6 0.0 2.8 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, N-terminal domain Zn_clus PF00172.18 KND87607.1 - 4.1e-08 33.2 5.8 9.6e-08 32.0 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_2 PF08028.11 KND87607.1 - 0.0025 18.1 3.5 0.0025 18.1 3.5 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 KND87608.1 - 6.5e-66 221.8 0.0 1.3e-65 220.9 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KND87608.1 - 1.2e-38 132.0 0.0 2.5e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KND87608.1 - 1.3e-27 96.0 0.0 2.7e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KND87608.1 - 5.5e-10 38.9 2.5 1.4e-09 37.7 2.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KND87608.1 - 1.3e-09 37.9 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KND87608.1 - 9.4e-08 31.8 0.2 3.4e-07 30.0 0.0 2.0 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KND87608.1 - 1.2e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 KND87608.1 - 0.021 14.7 0.2 0.042 13.7 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.6 KND87608.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Carboxyl_trans PF01039.22 KND87609.1 - 3.8e-84 283.1 0.0 9.8e-84 281.7 0.0 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.28 KND87610.1 - 2.2e-97 326.3 0.0 2.7e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND87610.1 - 7.8e-13 49.2 0.1 1.7e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HMGL-like PF00682.19 KND87611.1 - 1.8e-45 155.6 0.0 2.9e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 KND87611.1 - 2.1e-36 125.5 0.0 3.1e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND87611.1 - 3.7e-24 85.8 0.0 5.3e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAD_binding_4 PF01565.23 KND87612.1 - 3.4e-20 72.2 0.1 7e-20 71.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND87612.1 - 5.4e-09 36.0 0.3 1.8e-08 34.4 0.3 1.9 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KND87612.1 - 0.056 12.8 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding NDUF_B7 PF05676.13 KND87614.1 - 1e-29 102.0 5.0 1.2e-29 101.8 5.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KND87614.1 - 0.0072 16.3 1.8 0.01 15.8 1.8 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Amidohydro_1 PF01979.20 KND87617.1 - 3.5e-17 62.8 0.2 1e-15 57.9 0.2 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND87617.1 - 1.3e-12 47.9 5.0 3.6e-10 39.9 1.3 2.4 1 1 1 2 2 2 2 Amidohydrolase family AAA_33 PF13671.6 KND87618.1 - 1.3e-16 61.1 0.0 2.8e-16 60.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KND87618.1 - 1.3e-08 35.3 0.1 1.8e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND87618.1 - 1.3e-07 32.2 0.1 1.7e-07 31.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KND87618.1 - 4.8e-07 29.2 0.0 5.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 KND87618.1 - 1.8e-05 24.4 0.0 2.3e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SKI PF01202.22 KND87618.1 - 0.061 13.4 0.2 0.1 12.7 0.2 1.4 1 1 0 1 1 1 0 Shikimate kinase AAA PF00004.29 KND87618.1 - 0.11 13.0 0.0 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DnaJ_C PF01556.18 KND87619.1 - 1e-27 97.0 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND87619.1 - 2.2e-24 85.4 0.6 3.5e-24 84.7 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND87619.1 - 5.6e-14 52.3 16.8 9.4e-14 51.5 16.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 KND87619.1 - 0.00019 21.4 5.9 0.036 14.1 1.2 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KND87619.1 - 0.0014 18.5 9.6 0.15 12.1 0.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 KND87619.1 - 0.039 13.6 4.5 0.11 12.2 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Nop10p PF04135.12 KND87619.1 - 0.1 12.6 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family Lar_restr_allev PF14354.6 KND87619.1 - 0.69 10.3 6.9 9 6.8 5.7 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-RING_5 PF14634.6 KND87619.1 - 4.7 7.3 10.0 2.2 8.3 2.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain DUF3824 PF12868.7 KND87620.1 - 0.0015 19.2 6.4 0.0015 19.2 6.4 11.2 3 3 9 12 12 12 3 Domain of unknwon function (DUF3824) GST_N PF02798.20 KND87621.1 - 2.2e-10 40.7 0.0 3.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KND87621.1 - 3.6e-10 39.9 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND87621.1 - 2.7e-07 30.5 1.4 1.1e-06 28.5 0.1 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND87621.1 - 2.4e-06 27.9 0.0 4.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND87621.1 - 5.1e-06 26.7 0.0 9.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KND87621.1 - 1.2e-05 25.4 0.0 3.7e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KND87621.1 - 0.00083 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_C2 PF00648.21 KND87622.1 - 8.1e-61 205.6 0.4 3.8e-59 200.1 0.4 2.4 1 1 0 1 1 1 1 Calpain family cysteine protease DUF2102 PF09875.9 KND87622.1 - 2 8.2 8.3 0.73 9.6 5.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) FSA_C PF10479.9 KND87622.1 - 3.8 5.5 5.1 5.6 5.0 5.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 KND87622.1 - 7.1 4.7 12.8 11 4.1 12.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BaxI_1 PF12811.7 KND87623.1 - 0.34 10.4 1.8 0.51 9.9 1.8 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like FeoB_associated PF12669.7 KND87623.1 - 2.1 8.8 5.5 27 5.2 5.0 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein INT_SG_DDX_CT_C PF15300.6 KND87625.1 - 0.21 11.4 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Ribosomal_L32p PF01783.23 KND87626.1 - 0.17 12.1 4.3 0.4 11.0 4.3 1.6 1 0 0 1 1 1 0 Ribosomal L32p protein family TFB6 PF17110.5 KND87627.1 - 6.3e-64 214.8 0.0 9.5e-64 214.2 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 KND87627.1 - 7.7e-09 35.3 0.0 1.7e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 KND87628.1 - 7.7e-39 131.0 5.5 6.4e-08 33.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87628.1 - 1.8e-11 44.2 0.0 0.0042 17.3 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KND87628.1 - 0.012 15.5 1.3 19 5.3 0.1 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KND87628.1 - 0.018 14.1 0.1 2.6 6.9 0.0 3.0 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KND87628.1 - 0.03 13.1 1.8 6 5.5 0.2 3.1 1 1 3 4 4 4 0 Nup133 N terminal like WD40_like PF17005.5 KND87628.1 - 0.051 12.9 0.0 1.1 8.5 0.0 2.6 3 1 0 3 3 3 0 WD40-like domain TRAPP PF04051.16 KND87629.1 - 1.5e-35 122.1 0.0 1.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KND87629.1 - 0.0033 16.3 0.0 0.0041 16.0 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Lactamase_B PF00753.27 KND87633.1 - 2.4e-17 63.6 5.1 3.2e-17 63.2 5.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KND87633.1 - 3.1e-05 23.6 0.3 5.2e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2300 PF10062.9 KND87633.1 - 0.13 12.4 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Cerato-platanin PF07249.12 KND87634.1 - 2.9e-05 24.2 0.3 4.4e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Cerato-platanin RPA43_OB PF17875.1 KND87635.1 - 7.1e-33 113.9 0.1 7.1e-33 113.9 0.1 4.7 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I FHA PF00498.26 KND87636.1 - 0.00018 21.8 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND87636.1 - 0.00036 20.8 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PseudoU_synth_2 PF00849.22 KND87638.1 - 1.8e-29 102.9 0.0 2.7e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 KND87638.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 S4 domain Auto_anti-p27 PF06677.12 KND87638.1 - 0.047 13.8 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ub-Mut7C PF14451.6 KND87638.1 - 0.068 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin S36_mt PF10937.8 KND87639.1 - 1.4 10.6 5.2 0.68 11.5 1.8 2.0 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial Fungal_trans PF04082.18 KND87642.1 - 2.8e-12 46.2 0.0 4.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87642.1 - 8.8e-08 32.2 10.6 1.4e-07 31.5 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF16 PF01519.16 KND87642.1 - 0.21 12.1 0.1 0.42 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Glyco_hydro_3_C PF01915.22 KND87643.1 - 2e-59 201.0 0.0 3.4e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KND87643.1 - 7.6e-44 150.4 0.0 1.2e-43 149.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KND87643.1 - 1.1e-24 86.3 0.4 1e-23 83.2 0.3 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KND87643.1 - 3.3e-18 65.9 0.0 5.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_31 PF01055.26 KND87644.1 - 9.3e-157 522.7 1.3 1.2e-156 522.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KND87644.1 - 1.5e-39 134.8 0.0 2.5e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KND87644.1 - 4e-15 55.9 0.6 4e-15 55.9 0.6 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KND87644.1 - 0.024 14.9 0.2 0.078 13.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) LCCL PF03815.19 KND87645.1 - 1.7e-17 63.3 0.0 2.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 LCCL domain DUF4763 PF15960.5 KND87646.1 - 0.024 14.0 0.1 0.024 14.0 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4763) Noggin PF05806.12 KND87646.1 - 0.083 12.8 3.5 0.19 11.6 3.5 1.5 1 0 0 1 1 1 0 Noggin Spt20 PF12090.8 KND87646.1 - 4.7 6.8 44.5 4.9 6.7 27.3 2.4 2 0 0 2 2 2 0 Spt20 family DUF2464 PF10240.9 KND87646.1 - 4.9 6.6 8.8 8.5 5.9 8.8 1.3 1 0 0 1 1 1 0 Multivesicular body subunit 12 zf-UBR PF02207.20 KND87647.1 - 2.7e-14 53.1 5.3 2.7e-14 53.1 5.3 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 KND87648.1 - 1.3e-99 331.9 0.0 1.3e-99 331.9 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KND87648.1 - 1.6e-39 134.6 0.1 3e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KND87648.1 - 1.1e-32 113.4 29.3 1.1e-32 113.4 29.3 2.1 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KND87648.1 - 8.6e-25 87.0 0.2 2.1e-24 85.7 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND87648.1 - 4.5e-15 56.1 0.0 1.5e-14 54.4 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND87648.1 - 1.5e-07 31.1 0.0 8.5e-06 25.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND87648.1 - 3.3e-06 27.1 0.0 6.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KND87648.1 - 0.004 16.9 0.2 0.028 14.1 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 KND87648.1 - 0.0073 16.2 0.1 0.034 14.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sugar_tr PF00083.24 KND87650.1 - 2e-114 383.0 24.9 6.2e-114 381.3 24.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87650.1 - 1e-12 47.7 40.2 1.2e-07 31.0 13.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Mito_carr PF00153.27 KND87653.1 - 8e-53 176.3 0.3 6.6e-19 67.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SPW PF03779.14 KND87653.1 - 7.1 6.3 7.7 0.19 11.3 0.9 2.0 2 0 0 2 2 2 0 SPW repeat Cu-oxidase_3 PF07732.15 KND87654.1 - 1.4e-11 44.4 0.0 1e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND87654.1 - 3.7e-11 42.9 0.0 0.0007 19.3 0.1 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KND87654.1 - 0.0074 16.4 0.0 0.21 11.7 0.0 2.5 2 1 0 2 2 2 1 Cupredoxin-like domain Big_1 PF02369.16 KND87654.1 - 0.047 13.7 0.9 0.19 11.8 0.9 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Copper-bind PF00127.20 KND87654.1 - 0.075 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_3 PF07732.15 KND87656.1 - 1.5e-40 137.9 1.9 3.2e-40 136.9 0.2 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND87656.1 - 3.2e-32 111.1 8.5 2.8e-24 85.4 0.6 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KND87656.1 - 5.2e-11 42.9 1.0 4.6e-08 33.3 0.3 3.2 2 1 0 2 2 2 2 Multicopper oxidase F-box-like PF12937.7 KND87657.1 - 4.8e-05 23.2 1.0 4.8e-05 23.2 1.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND87657.1 - 0.0022 17.8 0.3 0.0053 16.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain DNA_pol_A_exo1 PF01612.20 KND87658.1 - 3.1e-15 56.3 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DLH PF01738.18 KND87659.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KND87659.1 - 0.0088 16.7 0.2 0.011 16.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND87659.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND87659.1 - 0.046 13.0 0.0 0.064 12.5 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 APH PF01636.23 KND87660.1 - 6e-11 42.7 0.6 0.00017 21.6 0.4 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KND87660.1 - 6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 KND87660.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 KND87660.1 - 0.11 12.0 0.1 1.1 8.8 0.1 2.1 1 1 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KND87662.1 - 9.9e-21 74.3 0.0 1.3e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87662.1 - 2.9e-15 56.2 0.0 5.2e-15 55.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND87662.1 - 0.0043 16.4 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND87662.1 - 0.02 14.2 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND87662.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KND87662.1 - 0.12 12.3 2.1 2.3 8.1 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87662.1 - 0.21 11.2 0.0 8 6.0 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase ChapFlgA_N PF17656.1 KND87663.1 - 0.014 15.6 0.1 0.023 14.8 0.1 1.3 1 0 0 1 1 1 0 FlgA N-terminal domain ISN1 PF06437.11 KND87664.1 - 7.7e-183 608.0 0.0 1.2e-182 607.4 0.0 1.3 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase IBN_N PF03810.19 KND87664.1 - 7.6e-13 48.2 4.4 6.1e-12 45.3 0.1 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.10 KND87664.1 - 3.9e-08 32.5 0.1 8.5e-08 31.4 0.1 1.5 1 0 0 1 1 1 1 Cse1 GRIP PF01465.20 KND87664.1 - 0.0026 17.6 0.0 0.011 15.6 0.0 2.2 1 0 0 1 1 1 1 GRIP domain Xpo1 PF08389.12 KND87664.1 - 0.0042 17.1 0.4 0.031 14.4 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein Glyco_transf_90 PF05686.12 KND87665.1 - 2.5e-06 26.7 0.0 0.0092 14.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 TPR_16 PF13432.6 KND87665.1 - 0.06 14.0 3.3 0.26 11.9 3.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.25 KND87666.1 - 2.6e-12 46.7 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87666.1 - 1e-07 31.5 0.0 4.2e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND87666.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND87666.1 - 0.055 12.8 0.0 0.082 12.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 KND87667.1 - 3e-30 105.5 0.0 4.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87667.1 - 6.6e-16 58.4 0.0 9.8e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND87667.1 - 0.0055 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND87667.1 - 0.085 12.8 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3040 PF11239.8 KND87669.1 - 0.063 13.5 8.5 0.61 10.4 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3863 PF12979.7 KND87669.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) XPA_C PF05181.12 KND87670.1 - 1.1e-25 89.3 1.6 2.2e-25 88.4 1.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus FRG1 PF06229.12 KND87670.1 - 0.013 15.2 0.8 0.031 14.0 0.8 1.6 1 0 0 1 1 1 0 FRG1-like domain zf-C3HC4_3 PF13920.6 KND87670.1 - 0.49 10.3 8.5 0.24 11.3 5.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XPA_N PF01286.18 KND87670.1 - 0.65 10.1 13.2 0.038 14.0 7.8 1.8 2 0 0 2 2 2 0 XPA protein N-terminal LicD PF04991.13 KND87671.1 - 2.4e-23 83.5 3.9 6.8e-17 62.4 2.6 2.2 1 1 1 2 2 2 2 LicD family GLTT PF01744.20 KND87671.1 - 0.011 15.5 3.5 0.02 14.6 3.5 1.4 1 0 0 1 1 1 0 GLTT repeat (6 copies) ABC_trans_aux PF03886.13 KND87671.1 - 0.037 13.6 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 ABC-type transport auxiliary lipoprotein component Clathrin PF00637.20 KND87672.1 - 6e-23 81.3 1.1 3.4e-21 75.6 0.6 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 KND87672.1 - 4.9e-18 65.1 0.4 9.6e-18 64.1 0.4 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KND87672.1 - 3.8e-07 30.0 4.0 1.1e-06 28.5 4.0 1.9 1 1 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 KND87672.1 - 0.001 18.9 3.0 0.0023 17.7 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND87672.1 - 0.0026 17.7 3.2 0.0053 16.7 3.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND87672.1 - 0.035 14.4 3.2 0.096 13.0 3.2 1.8 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 KND87672.1 - 0.069 13.2 0.9 0.16 12.0 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KND87672.1 - 0.1 12.6 2.3 0.32 11.1 2.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KND87672.1 - 0.22 11.8 2.4 0.56 10.5 2.4 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND87672.1 - 0.63 10.0 6.9 0.1 12.5 2.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 KND87672.1 - 6.1 7.9 5.6 47 5.2 0.1 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat Striatin PF08232.12 KND87673.1 - 7.9e-41 140.2 6.6 1.6e-40 139.3 6.6 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 KND87673.1 - 9.9e-25 86.3 17.9 7.3e-05 23.5 0.1 7.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87673.1 - 5.8e-06 26.5 0.0 2.7 8.4 0.0 5.0 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KND87673.1 - 0.1 11.1 0.0 0.29 9.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain ADH_N_2 PF16884.5 KND87673.1 - 0.12 12.3 0.2 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase eIF2A PF08662.11 KND87673.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND87673.1 - 0.24 10.3 0.0 1.1 8.1 0.0 2.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3450 PF11932.8 KND87673.1 - 0.33 10.2 5.5 0.19 11.0 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4482 PF14818.6 KND87673.1 - 2.3 9.1 11.0 0.63 10.9 7.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) HET PF06985.11 KND87674.1 - 8.4e-24 84.6 0.0 5.7e-23 81.9 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 KND87675.1 - 4e-20 72.1 0.0 3e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND87675.1 - 3.9e-13 49.5 1.3 2.5e-12 46.9 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND87675.1 - 0.00032 20.6 1.0 0.00052 20.0 0.2 1.7 2 0 0 2 2 2 1 KR domain Kinesin PF00225.23 KND87678.1 - 8.4e-89 297.8 0.1 8.4e-89 297.8 0.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND87678.1 - 4.2e-16 59.2 0.0 4e-14 52.8 0.0 3.0 2 0 0 2 2 2 1 Microtubule binding Holin_BhlA PF10960.8 KND87678.1 - 0.23 11.5 4.6 5.5 7.0 0.2 4.3 3 0 0 3 3 3 0 BhlA holin family DNA_Packaging PF11053.8 KND87678.1 - 0.3 10.9 5.4 0.21 11.5 1.8 2.6 2 0 0 2 2 2 0 Terminase DNA packaging enzyme APH PF01636.23 KND87680.1 - 4.3e-18 66.1 0.2 7.8e-18 65.3 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND87680.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DNA_binding_1 PF01035.20 KND87681.1 - 5.9e-25 87.2 0.2 7.7e-25 86.8 0.2 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Folate_carrier PF01770.18 KND87681.1 - 0.22 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier SfLAP PF11139.8 KND87682.1 - 0.047 13.1 0.2 0.052 13.0 0.2 1.0 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF2070 PF09843.9 KND87683.1 - 6 5.0 9.9 8 4.6 9.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) APH PF01636.23 KND87685.1 - 0.0001 22.3 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ERCC4 PF02732.15 KND87686.1 - 1.6e-25 90.2 0.0 2.7e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF2172 PF09940.9 KND87686.1 - 0.13 12.7 0.1 0.53 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2172) PBP_sp32 PF07222.12 KND87686.1 - 0.15 11.5 1.5 0.27 10.7 1.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 His_Phos_1 PF00300.22 KND87687.1 - 1.7e-25 89.9 0.1 3.9e-25 88.7 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TPP_enzyme_N PF02776.18 KND87688.1 - 1.6e-28 99.5 0.9 8e-27 93.9 0.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KND87688.1 - 3.9e-22 78.7 0.0 9.2e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND87688.1 - 4e-10 39.6 0.0 1.4e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 KND87688.1 - 2.2 8.6 10.2 0.17 12.2 2.0 3.3 3 1 1 4 4 4 0 MobA-like NTP transferase domain Metallophos PF00149.28 KND87689.1 - 9.8e-15 55.6 0.0 1.7e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KND87689.1 - 1.3e-13 51.6 0.0 2.9e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KND87689.1 - 2e-12 47.5 1.4 2e-12 47.5 1.4 1.7 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KND87689.1 - 4.5e-05 23.9 0.3 0.00061 20.3 0.1 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain ADD_DNMT3 PF17980.1 KND87689.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 fn3 PF00041.21 KND87689.1 - 0.1 12.9 0.4 0.23 11.8 0.4 1.5 1 0 0 1 1 1 0 Fibronectin type III domain SDF PF00375.18 KND87689.1 - 0.15 11.1 0.4 0.22 10.5 0.4 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Peptidase_S10 PF00450.22 KND87691.1 - 4.5e-80 270.1 4.4 9.2e-80 269.1 4.4 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 KND87692.1 - 3.2e-31 108.5 32.6 6.1e-31 107.6 32.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AnkUBD PF18418.1 KND87692.1 - 0.063 13.4 0.4 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain SLATT_1 PF18181.1 KND87692.1 - 1.6 8.6 4.3 1e+02 2.8 0.0 3.1 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 KND87692.1 - 9.7 6.7 9.0 1.5 9.3 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) IMS PF00817.20 KND87693.1 - 3.1e-40 137.6 0.0 6.6e-40 136.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KND87693.1 - 5.1e-15 56.2 0.0 1e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KND87693.1 - 3.5e-11 42.5 3.0 7e-11 41.5 3.0 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KND87693.1 - 0.002 18.3 0.1 0.034 14.5 0.0 2.6 3 0 0 3 3 3 1 IMS family HHH motif zf-C2H2_4 PF13894.6 KND87693.1 - 0.11 13.4 0.2 0.57 11.2 0.2 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger Acyl_transf_1 PF00698.21 KND87695.1 - 5.8e-60 203.5 0.0 9.6e-60 202.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KND87695.1 - 4.1e-56 189.7 0.0 9.6e-56 188.5 0.0 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 KND87695.1 - 6.4e-56 189.7 0.5 1.3e-55 188.8 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KND87695.1 - 7.3e-55 186.3 0.0 1.2e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KND87695.1 - 4.8e-32 110.5 0.1 1.8e-31 108.6 0.1 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KND87695.1 - 2.1e-18 66.9 0.0 5.4e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KND87695.1 - 4.1e-16 59.4 0.1 1.2e-09 38.7 0.0 2.5 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 KND87695.1 - 4.2e-12 47.3 0.0 5.1e-11 43.8 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND87695.1 - 1.6e-10 41.1 0.0 7.8e-10 38.8 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KND87695.1 - 1.7e-10 41.5 0.0 9.5e-10 39.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87695.1 - 3.2e-10 40.5 0.0 2.2e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87695.1 - 1e-09 38.5 0.0 2.6e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87695.1 - 2.3e-08 34.0 0.0 8.3e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KND87695.1 - 1.6e-07 31.0 0.5 4.8e-06 26.2 0.2 3.2 2 1 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 KND87695.1 - 1.5e-06 28.0 0.9 4e-06 26.7 0.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KND87695.1 - 3.2e-06 27.4 0.0 2e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 KND87695.1 - 0.00023 20.6 0.0 0.00063 19.2 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 KND87695.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KND87695.1 - 0.017 14.9 0.0 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase ACP_syn_III PF08545.10 KND87695.1 - 0.057 13.3 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 KND87698.1 - 2.6e-37 128.7 0.0 5e-21 75.0 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 KND87699.1 - 1.3e-19 70.3 27.7 1.3e-19 70.3 27.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87699.1 - 0.00025 20.0 3.5 0.00025 20.0 3.5 2.7 1 1 0 2 2 2 1 Sugar (and other) transporter DUF4149 PF13664.6 KND87699.1 - 0.46 10.8 8.3 0.57 10.5 5.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) SDA1 PF05285.12 KND87700.1 - 5.5e-80 269.4 48.9 1.6e-46 159.3 11.6 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KND87700.1 - 2.8e-22 78.8 0.9 6e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 NUC130/3NT domain Mito_carr PF00153.27 KND87701.1 - 5e-43 145.0 7.6 6.2e-16 58.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EI24 PF07264.11 KND87702.1 - 0.00054 20.2 0.2 0.00065 20.0 0.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ADH_N PF08240.12 KND87704.1 - 6.2e-20 71.1 3.2 9.5e-20 70.5 3.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND87704.1 - 8.2e-20 71.1 0.0 1.4e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND87704.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KND87704.1 - 0.0063 15.9 0.1 0.0099 15.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hid1 PF12722.7 KND87705.1 - 0.58 8.2 4.3 0.73 7.9 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ank_4 PF13637.6 KND87706.1 - 1.3e-15 57.6 2.9 1.1e-06 29.1 0.1 6.1 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND87706.1 - 2.6e-14 53.1 8.1 5.8e-08 32.9 1.2 4.6 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87706.1 - 3.6e-12 46.7 0.2 7.9e-08 32.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KND87706.1 - 6.5e-12 45.3 5.9 0.00098 19.5 0.2 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 KND87706.1 - 1.9e-08 33.9 2.9 0.0054 17.1 0.1 4.7 4 1 0 4 4 4 2 Ankyrin repeat Epimerase PF01370.21 KND87707.1 - 1.1e-23 84.0 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND87707.1 - 2.4e-18 66.6 0.0 2.9e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND87707.1 - 1.4e-11 44.0 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KND87707.1 - 8.9e-06 25.0 0.0 2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KND87707.1 - 8.6e-05 21.8 0.1 0.28 10.3 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 KND87707.1 - 0.0001 21.8 0.0 0.00022 20.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.23 KND87707.1 - 0.00012 22.2 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KND87707.1 - 0.00049 20.0 0.0 0.00072 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KND87707.1 - 0.0034 16.6 0.0 0.062 12.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KND87707.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 KND87707.1 - 0.22 11.1 0.0 1.5 8.3 0.0 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ABC2_membrane PF01061.24 KND87708.1 - 3.7e-77 258.5 70.9 1.6e-41 142.0 23.6 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KND87708.1 - 8.2e-33 112.2 3.4 4e-27 93.9 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KND87708.1 - 8.4e-29 100.8 0.0 3.9e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KND87708.1 - 1.1e-12 48.4 0.2 3.3e-12 46.8 0.2 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KND87708.1 - 8.7e-10 38.2 43.1 6.1e-07 28.9 13.0 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KND87708.1 - 7.4e-07 28.9 0.1 0.0011 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND87708.1 - 2.6e-06 27.9 0.2 0.0011 19.4 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND87708.1 - 0.00022 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 KND87708.1 - 0.00086 19.9 0.0 0.0053 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND87708.1 - 0.00097 19.1 0.1 0.21 11.5 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 KND87708.1 - 0.002 17.8 0.1 0.055 13.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KND87708.1 - 0.003 17.7 0.4 0.18 11.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KND87708.1 - 0.0037 17.5 0.4 0.22 11.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KND87708.1 - 0.004 17.0 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KND87708.1 - 0.0071 16.6 0.3 0.022 15.0 0.3 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND87708.1 - 0.0076 16.0 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KND87708.1 - 0.027 14.5 0.4 0.54 10.3 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 KND87708.1 - 0.028 14.0 0.4 0.63 9.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KND87708.1 - 0.03 14.8 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KND87708.1 - 0.03 14.8 0.3 3.1 8.2 0.1 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND87708.1 - 0.041 13.6 0.1 0.52 10.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KND87708.1 - 0.053 12.6 0.1 8.2 5.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Pantoate_ligase PF02569.15 KND87708.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase AAA_23 PF13476.6 KND87708.1 - 0.16 12.4 0.1 0.16 12.4 0.1 2.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 KND87708.1 - 0.26 11.6 0.4 40 4.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 KND87710.1 - 2.1e-33 115.7 34.6 2.3e-28 99.1 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.13 KND87711.1 - 4.9e-29 101.5 0.0 6.6e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) adh_short_C2 PF13561.6 KND87713.1 - 4.9e-55 186.6 0.0 5.6e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87713.1 - 2.8e-45 154.2 0.0 3.5e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND87713.1 - 2.1e-06 27.8 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KND87713.1 - 7.8e-05 22.2 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KND87713.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ysc84 PF04366.12 KND87714.1 - 1.5e-52 176.7 0.4 2.7e-52 175.9 0.4 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator TFIIA PF03153.13 KND87714.1 - 0.65 9.9 33.5 0.099 12.6 29.7 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 KND87714.1 - 4.3 5.9 11.8 6.8 5.3 11.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pho88 PF10032.9 KND87716.1 - 5.9e-82 273.3 1.4 7.3e-82 273.0 1.4 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Fungal_trans_2 PF11951.8 KND87717.1 - 1.2e-16 60.5 0.0 2.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87717.1 - 6.4e-09 35.8 13.1 9.6e-09 35.2 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-URI2 PF15653.6 KND87717.1 - 0.039 14.2 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 URI fold toxin 2 DHDPS PF00701.22 KND87718.1 - 6.3e-46 156.4 0.0 7.4e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Catalase-rel PF06628.12 KND87718.1 - 0.12 12.6 0.1 3.4 7.9 0.0 2.5 2 1 1 3 3 3 0 Catalase-related immune-responsive ABC_membrane PF00664.23 KND87719.1 - 4.3e-88 295.5 39.1 5.8e-49 167.2 14.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND87719.1 - 1.1e-67 226.8 0.1 2.9e-32 112.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 KND87719.1 - 5.4e-12 45.6 2.8 0.00012 21.6 0.1 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND87719.1 - 3.1e-10 40.4 0.2 0.066 13.0 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KND87719.1 - 1.9e-07 31.2 0.0 0.023 14.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KND87719.1 - 3e-07 29.6 1.0 0.0014 17.5 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KND87719.1 - 7e-07 29.8 3.7 0.0021 18.5 0.3 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 KND87719.1 - 1.9e-06 27.5 0.3 0.033 13.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KND87719.1 - 2e-05 24.5 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND87719.1 - 2.8e-05 24.4 0.3 0.028 14.7 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KND87719.1 - 0.00013 22.5 0.0 0.092 13.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 KND87719.1 - 0.00036 20.6 0.0 0.52 10.3 0.0 3.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KND87719.1 - 0.00077 19.5 0.0 1 9.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 KND87719.1 - 0.003 17.3 0.7 0.86 9.3 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KND87719.1 - 0.0033 17.0 0.4 0.69 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 KND87719.1 - 0.0071 15.6 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 KND87719.1 - 0.01 16.4 0.0 0.76 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND87719.1 - 0.018 15.1 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 KND87719.1 - 0.022 13.8 0.0 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 KND87719.1 - 0.04 14.0 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 KND87719.1 - 0.045 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit SbcCD_C PF13558.6 KND87719.1 - 0.072 13.3 1.0 11 6.3 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 KND87719.1 - 0.078 13.1 0.0 15 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 KND87719.1 - 0.11 11.9 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KND87719.1 - 0.12 11.9 0.0 21 4.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 KND87719.1 - 0.21 11.3 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FMO-like PF00743.19 KND87721.1 - 1.8e-33 115.8 0.1 2.2e-23 82.5 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND87721.1 - 6.1e-15 55.3 0.0 3.1e-12 46.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND87721.1 - 3.4e-10 39.7 0.0 8.1e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND87721.1 - 4.8e-10 39.1 0.0 2.5e-08 33.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KND87721.1 - 2.3e-05 24.5 0.2 0.0013 18.7 0.2 2.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 KND87721.1 - 0.00013 21.7 1.7 0.28 10.7 0.0 2.9 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND87721.1 - 0.0011 19.1 0.1 0.0063 16.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KND87721.1 - 0.081 11.6 0.1 4.6 5.8 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 KND87721.1 - 1 8.6 2.5 1.8 7.7 0.0 2.2 2 1 0 3 3 3 0 FAD binding domain Glyco_hydro_18 PF00704.28 KND87722.1 - 2e-24 86.9 0.8 3.2e-24 86.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.24 KND87723.1 - 7.9e-105 351.3 25.8 9.6e-105 351.0 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND87723.1 - 3.3e-25 88.8 29.7 3.3e-25 88.8 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_S8 PF00082.22 KND87724.1 - 4.5e-20 72.1 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Subtilase family SLD3 PF08639.10 KND87725.1 - 0.013 14.3 0.2 0.024 13.4 0.2 1.4 1 0 0 1 1 1 0 DNA replication regulator SLD3 zf-Di19 PF05605.12 KND87725.1 - 0.26 11.6 4.5 20 5.5 0.3 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_S41 PF03572.18 KND87726.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Pns11_12 PF17464.2 KND87727.1 - 0.031 14.0 0.6 0.055 13.2 0.6 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 TRAM_LAG1_CLN8 PF03798.16 KND87728.1 - 2.6e-47 161.1 18.6 2.6e-47 161.1 18.6 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KND87728.1 - 7e-21 73.6 0.2 7e-21 73.6 0.2 2.3 2 0 0 2 2 2 1 TRAM1-like protein Gly_transf_sug PF04488.15 KND87730.1 - 1.6e-15 57.5 0.0 3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RRM_1 PF00076.22 KND87731.1 - 3.9e-14 52.2 0.0 4.4e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND87731.1 - 0.004 17.2 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif WD40 PF00400.32 KND87732.1 - 3.6e-07 30.8 0.1 0.15 13.0 0.0 4.0 2 1 1 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87732.1 - 0.00018 21.8 0.0 0.0057 16.9 0.0 3.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 KND87732.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 KND87732.1 - 0.0033 15.5 0.0 0.0076 14.3 0.0 1.6 2 0 0 2 2 2 1 IKI3 family Ge1_WD40 PF16529.5 KND87732.1 - 0.034 13.1 0.1 1.6 7.6 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Septin PF00735.18 KND87734.1 - 1.6e-103 345.9 0.1 5.2e-103 344.2 0.0 1.9 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KND87734.1 - 0.00014 21.9 0.0 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KND87734.1 - 0.00046 20.3 0.5 0.78 9.8 0.0 3.0 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KND87734.1 - 0.0066 16.4 0.1 0.09 12.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KND87734.1 - 0.041 14.2 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KND87734.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain EB1 PF03271.17 KND87734.1 - 0.16 12.3 1.7 4.5 7.6 1.3 2.5 2 0 0 2 2 2 0 EB1-like C-terminal motif AAA_24 PF13479.6 KND87734.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain QRPTase_C PF01729.19 KND87735.1 - 4.2e-55 186.1 0.3 5.1e-55 185.8 0.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KND87735.1 - 1.9e-17 63.1 0.2 7.9e-17 61.1 0.0 2.1 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Cu_amine_oxid PF01179.20 KND87736.1 - 4.8e-133 444.1 0.0 1.1e-131 439.6 0.0 2.0 1 1 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KND87736.1 - 2.2e-07 31.2 0.0 4.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KND87736.1 - 0.0022 18.2 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pkinase PF00069.25 KND87737.1 - 6.2e-55 186.4 0.3 2e-35 122.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND87737.1 - 3.4e-37 128.1 0.0 8.6e-37 126.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND87737.1 - 4.7e-05 22.8 0.0 8.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like G-gamma PF00631.22 KND87737.1 - 0.11 12.5 0.0 0.76 9.8 0.1 2.4 2 0 0 2 2 2 0 GGL domain DUF3896 PF13035.6 KND87737.1 - 0.16 12.2 0.2 0.44 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Macoilin PF09726.9 KND87737.1 - 0.18 10.3 2.2 0.31 9.6 2.2 1.4 1 0 0 1 1 1 0 Macoilin family APH PF01636.23 KND87737.1 - 0.46 10.4 5.5 0.58 10.0 0.2 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family OmpH PF03938.14 KND87737.1 - 0.94 9.8 4.8 2 8.8 4.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 KND87737.1 - 8.4 6.8 15.3 20 5.6 15.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) BTB PF00651.31 KND87738.1 - 9e-25 87.1 0.0 3.9e-12 46.4 0.3 3.1 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 KND87738.1 - 2.2e-07 31.3 0.1 7.4e-07 29.6 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND87738.1 - 1.5e-06 28.7 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND87738.1 - 2.8e-05 24.2 0.4 0.23 12.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KND87738.1 - 3.8e-05 23.9 0.5 0.017 15.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KND87738.1 - 6.1e-05 23.2 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Pox_P4B PF03292.14 KND87738.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Choline_kinase PF01633.20 KND87739.1 - 5.9e-60 202.5 0.0 1.2e-59 201.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KND87739.1 - 3.9e-19 68.0 0.0 7.9e-19 67.1 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 KND87739.1 - 1.5e-06 28.3 0.5 1.5e-06 28.3 0.5 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RNA_capsid PF03035.14 KND87739.1 - 1.5 8.8 3.9 1.5 8.8 2.4 1.7 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein SCO1-SenC PF02630.14 KND87740.1 - 1.1e-47 161.3 0.0 3.3e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 SCO1/SenC Hydrolase_6 PF13344.6 KND87740.1 - 7.7e-20 70.9 0.0 1.8e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND87740.1 - 2.8e-16 59.3 0.6 1.2e-15 57.3 0.1 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KND87740.1 - 1.9e-06 28.3 0.0 0.21 11.9 0.0 4.3 2 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 KND87740.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family PHD PF00628.29 KND87741.1 - 5.7e-10 38.9 11.5 5.7e-10 38.9 11.5 1.9 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 KND87741.1 - 1.2 9.3 10.0 3.5 7.8 10.0 1.9 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.32 KND87742.1 - 2.8e-19 69.1 7.3 0.018 15.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND87742.1 - 1.7e-05 25.0 0.0 3.4 8.0 0.0 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GDC-P PF02347.16 KND87743.1 - 7e-157 522.7 0.0 1.1e-144 482.5 0.0 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KND87743.1 - 0.00012 21.5 0.0 0.00027 20.3 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase Tom5 PF10642.9 KND87744.1 - 3.8e-21 74.8 1.5 4.1e-21 74.7 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 KND87745.1 - 1.3e-38 132.2 1.0 1.3e-38 132.2 1.0 2.3 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 KND87745.1 - 7.6e-16 57.4 1.5 1.9e-15 56.1 1.5 1.7 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain YliH PF10799.8 KND87745.1 - 0.044 13.7 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DivIVA PF05103.13 KND87745.1 - 0.056 13.5 5.9 0.14 12.2 0.1 3.0 2 1 1 3 3 3 0 DivIVA protein YnfE PF17452.2 KND87745.1 - 0.06 13.6 0.2 5.8 7.3 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized YnfE-like DUF4407 PF14362.6 KND87745.1 - 0.063 12.6 2.3 0.12 11.7 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 KND87745.1 - 0.1 12.6 0.3 1 9.4 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3782 PF12644.7 KND87745.1 - 0.17 12.0 2.2 8 6.7 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) WD40_alt PF14077.6 KND87745.1 - 0.21 11.5 0.6 2.4 8.1 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif CENP-F_leu_zip PF10473.9 KND87745.1 - 0.34 10.9 8.1 4.1 7.4 0.1 3.2 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_MT_bd PF06657.13 KND87745.1 - 1.2 9.7 6.1 3.9 8.0 0.2 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.6 KND87745.1 - 1.6 8.0 8.0 1.6 8.0 0.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CLZ PF16526.5 KND87745.1 - 2 8.8 7.3 6.6 7.2 0.2 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 KND87745.1 - 2.2 8.6 5.0 16 5.8 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 KND87745.1 - 3 8.2 7.5 16 5.8 0.1 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CCDC-167 PF15188.6 KND87745.1 - 4.5 7.7 9.9 17 5.8 0.4 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Formyl_trans_N PF00551.19 KND87747.1 - 7.8e-33 113.7 0.3 9.8e-32 110.1 0.3 2.0 1 1 0 1 1 1 1 Formyl transferase Abhydrolase_2 PF02230.16 KND87748.1 - 2.3e-47 161.6 0.0 2.6e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KND87748.1 - 2.3e-06 28.4 0.2 2.8e-06 28.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND87748.1 - 3.9e-06 26.3 0.2 0.18 11.0 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND87748.1 - 0.00023 20.9 0.5 0.002 17.8 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 KND87748.1 - 0.0023 17.6 0.0 0.005 16.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KND87748.1 - 0.028 14.3 0.5 0.073 12.9 0.0 1.9 2 1 1 3 3 3 0 alpha/beta hydrolase fold SLH PF00395.20 KND87748.1 - 0.037 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 S-layer homology domain Cutinase PF01083.22 KND87748.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase PF00151.19 KND87748.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF2974 PF11187.8 KND87748.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RTC PF01137.21 KND87749.1 - 5.9e-53 179.3 0.0 1e-52 178.6 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Methyltransf_25 PF13649.6 KND87750.1 - 6.4e-11 42.8 0.0 1.2e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87750.1 - 8.6e-09 35.9 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND87750.1 - 2.3e-07 30.8 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87750.1 - 4.3e-07 29.9 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87750.1 - 7.1e-07 29.9 0.0 1.2e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND87750.1 - 0.00062 19.2 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KND87750.1 - 0.0016 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND87750.1 - 0.0046 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KND87750.1 - 0.042 12.8 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NodS PF05401.11 KND87750.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) SAM_MT PF04445.13 KND87750.1 - 0.091 12.2 0.0 0.2 11.0 0.0 1.5 1 1 1 2 2 2 0 Putative SAM-dependent methyltransferase Glyco_hydro_125 PF06824.11 KND87751.1 - 2.3e-150 501.1 0.0 2.6e-150 500.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) TPR_2 PF07719.17 KND87752.1 - 8.4e-13 47.4 7.1 2.5e-05 24.1 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND87752.1 - 2.5e-09 36.6 0.3 0.0006 19.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND87752.1 - 1.8e-07 30.7 0.0 0.0082 15.8 0.0 4.7 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.6 KND87752.1 - 1.5e-06 28.3 4.9 0.69 10.2 0.2 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND87752.1 - 3e-05 23.9 1.4 3.9 7.9 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND87752.1 - 4.7e-05 23.1 0.8 0.68 10.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND87752.1 - 8.2e-05 23.1 23.8 2.4 9.2 0.0 8.4 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND87752.1 - 8.3e-05 23.0 10.5 0.19 12.2 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND87752.1 - 0.021 15.2 1.6 19 5.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND87752.1 - 0.024 14.5 6.9 5 7.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KND87752.1 - 0.076 13.7 0.0 0.076 13.7 0.0 6.4 5 1 0 6 6 6 0 Tetratricopeptide repeat Myc_N PF01056.18 KND87753.1 - 0.15 11.9 5.4 0.063 13.2 2.8 1.6 2 0 0 2 2 2 0 Myc amino-terminal region OmpH PF03938.14 KND87753.1 - 0.29 11.5 15.7 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SAPS PF04499.15 KND87753.1 - 0.36 9.5 2.7 0.49 9.1 2.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IMD PF08397.11 KND87753.1 - 0.49 9.7 14.8 0.012 15.0 3.7 2.8 2 1 0 2 2 2 0 IRSp53/MIM homology domain RR_TM4-6 PF06459.12 KND87753.1 - 3.7 7.3 7.3 7.4 6.3 7.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 KND87753.1 - 6.6 5.7 10.8 10 5.1 10.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PDZ_assoc PF10600.9 KND87754.1 - 3.4 8.6 8.3 0.58 11.0 2.7 2.6 3 0 0 3 3 3 0 PDZ-associated domain of NMDA receptors ABC_tran PF00005.27 KND87755.1 - 1.2e-44 152.1 0.0 3.6e-24 85.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND87755.1 - 1.6e-44 152.6 23.3 3.7e-32 112.1 9.3 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 KND87755.1 - 5.8e-06 26.3 0.1 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KND87755.1 - 6.5e-06 25.8 0.8 0.086 12.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KND87755.1 - 7.2e-06 25.6 0.4 0.056 12.9 0.1 3.8 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KND87755.1 - 2e-05 25.2 0.1 0.0077 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND87755.1 - 3.1e-05 24.4 0.2 0.3 11.4 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KND87755.1 - 0.00018 21.6 0.4 0.16 12.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KND87755.1 - 0.00033 20.8 1.3 0.006 16.7 0.1 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 KND87755.1 - 0.00049 20.4 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KND87755.1 - 0.0013 18.2 0.2 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 KND87755.1 - 0.0013 18.3 0.1 1.1 8.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KND87755.1 - 0.003 17.4 4.5 0.42 10.4 0.3 3.5 2 2 2 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 KND87755.1 - 0.012 15.7 0.0 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND87755.1 - 0.013 14.8 0.4 3.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 KND87755.1 - 0.03 13.4 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KND87755.1 - 0.059 13.1 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KND87755.1 - 0.061 13.2 3.2 4.7 7.1 1.0 3.0 2 1 0 2 2 2 0 NACHT domain Pox_A32 PF04665.12 KND87755.1 - 0.064 12.7 1.1 4 6.8 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.23 KND87755.1 - 0.07 13.2 2.7 2 8.5 0.2 2.5 2 0 0 2 2 2 0 Dynamin family DUF716 PF04819.12 KND87755.1 - 0.099 12.3 0.1 0.099 12.3 0.1 3.6 3 1 1 4 4 3 0 Family of unknown function (DUF716) AIG1 PF04548.16 KND87755.1 - 0.18 11.1 0.2 14 4.9 0.3 2.3 2 0 0 2 2 2 0 AIG1 family AAA_7 PF12775.7 KND87755.1 - 0.18 11.3 0.1 3 7.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PsbJ PF01788.17 KND87755.1 - 6.8 6.7 7.7 7.6 6.5 0.0 3.4 3 0 0 3 3 3 0 PsbJ TPR_10 PF13374.6 KND87757.1 - 8.1e-45 149.5 3.4 8.1e-10 38.3 0.0 6.5 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 KND87757.1 - 9.9e-38 128.3 1.6 1.1e-14 54.4 0.0 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KND87757.1 - 5.7e-15 54.2 1.7 0.039 14.0 0.0 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 KND87757.1 - 1.1e-10 40.8 1.7 0.28 11.4 0.1 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KND87757.1 - 3e-09 36.7 2.1 5.3e-09 35.9 2.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 KND87757.1 - 1.2e-08 34.7 0.0 0.62 10.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND87757.1 - 7e-08 32.0 1.9 0.049 13.5 0.1 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND87757.1 - 8.9e-08 32.7 0.0 0.00058 20.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND87757.1 - 0.00018 21.5 0.9 0.34 11.2 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND87757.1 - 0.00018 21.9 0.0 0.59 10.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND87757.1 - 0.00063 20.3 1.4 19 6.4 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND87757.1 - 0.0012 19.3 1.2 5.6 7.9 0.0 4.8 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND87757.1 - 0.0018 18.8 3.8 20 6.1 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 KND87757.1 - 0.017 15.3 0.5 23 5.5 0.0 3.9 4 0 0 4 4 3 0 PPR repeat Abhydrolase_6 PF12697.7 KND87757.1 - 0.019 15.6 0.0 0.06 13.9 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family NB-ARC PF00931.22 KND87757.1 - 0.058 12.6 0.0 0.17 11.0 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KND87757.1 - 0.082 13.2 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1897 PF09005.10 KND87757.1 - 0.083 12.4 5.6 4.2 6.9 0.1 3.5 4 0 0 4 4 3 0 Domain of unknown function (DUF1897) CbtB PF09489.10 KND87757.1 - 2 8.6 4.5 4.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF4033 PF13225.6 KND87758.1 - 0.021 14.8 0.5 0.045 13.7 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4033) DUF3435 PF11917.8 KND87759.1 - 5.9e-55 186.9 0.0 4.8e-41 141.1 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) LRV PF01816.17 KND87759.1 - 0.017 15.5 0.2 0.31 11.5 0.0 2.9 2 0 0 2 2 2 0 Leucine rich repeat variant Glyco_hydro_18 PF00704.28 KND87760.1 - 1.6e-32 113.5 1.3 1.6e-32 113.5 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Antimicrobial17 PF08129.11 KND87760.1 - 0.0018 18.2 0.2 0.23 11.5 0.0 3.4 3 0 0 3 3 3 1 Alpha/beta enterocin family Adeno_hexon PF01065.19 KND87760.1 - 0.0076 15.2 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 Hexon, adenovirus major coat protein, N-terminal domain FHA PF00498.26 KND87761.1 - 1.9e-17 63.3 0.1 8e-17 61.4 0.0 2.2 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 KND87761.1 - 9.9e-05 22.6 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 KND87761.1 - 0.004 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 YhfZ C-terminal domain DHR10 PF18595.1 KND87761.1 - 0.0048 16.9 21.6 0.024 14.7 1.6 3.2 3 0 0 3 3 3 2 Designed helical repeat protein 10 domain Vps51 PF08700.11 KND87761.1 - 0.82 9.8 8.8 5.7 7.1 1.5 3.1 3 0 0 3 3 3 0 Vps51/Vps67 Sec2p PF06428.11 KND87761.1 - 1.2 9.1 9.9 1.6 8.7 0.4 2.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p GAS PF13851.6 KND87761.1 - 2.8 7.2 20.0 0.019 14.3 3.7 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3037 PF11236.8 KND87761.1 - 8 6.9 7.1 2.5 8.5 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Fez1 PF06818.15 KND87761.1 - 9.3 6.7 19.6 2.6 8.4 15.8 1.9 1 1 0 1 1 1 0 Fez1 Romo1 PF10247.9 KND87762.1 - 8.2e-16 58.1 13.4 5.2e-14 52.4 13.4 2.3 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SIR2 PF02146.17 KND87763.1 - 4.5e-55 186.3 0.0 6.8e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf_UBZ PF18439.1 KND87763.1 - 0.092 12.4 0.5 0.18 11.4 0.5 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger CBFD_NFYB_HMF PF00808.23 KND87764.1 - 1.7e-17 63.4 0.6 2.9e-17 62.7 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND87764.1 - 0.00022 21.6 0.1 0.001 19.4 0.0 1.9 1 1 2 3 3 3 1 Core histone H2A/H2B/H3/H4 adh_short PF00106.25 KND87766.1 - 2.2e-39 135.0 0.0 2.6e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND87766.1 - 1.9e-29 102.9 0.0 2.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND87766.1 - 1.1e-09 38.5 0.1 1.5e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KND87766.1 - 0.0086 16.0 0.1 0.021 14.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KND87766.1 - 0.035 13.6 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family S-methyl_trans PF02574.16 KND87767.1 - 4.1e-47 161.2 0.0 4.9e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase TetR_C_14 PF17754.1 KND87767.1 - 0.045 13.7 0.1 0.045 13.7 0.1 2.1 2 0 0 2 2 2 0 MftR C-terminal domain Prp19 PF08606.11 KND87767.1 - 0.8 9.7 2.1 2.1 8.4 2.1 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like Glyco_hydro_18 PF00704.28 KND87771.1 - 9.5e-08 32.1 0.3 1.7e-07 31.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KND87771.1 - 3.1e-07 30.3 0.0 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KND87771.1 - 3.8e-05 24.1 8.5 3.8e-05 24.1 8.5 3.6 3 1 0 3 3 3 1 Chitin recognition protein Thioredox_DsbH PF03190.15 KND87773.1 - 1.2e-60 204.1 0.0 2e-60 203.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KND87773.1 - 0.00087 19.4 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DLIC PF05783.11 KND87774.1 - 1.1e-29 103.7 0.0 1.8e-28 99.7 0.0 2.4 2 1 1 3 3 3 1 Dynein light intermediate chain (DLIC) CAP PF00188.26 KND87775.1 - 1.9e-19 70.8 3.5 2.6e-19 70.3 3.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CHCH PF06747.13 KND87776.1 - 5.2e-08 32.8 13.9 1.8e-06 27.9 3.9 2.7 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KND87776.1 - 0.00042 20.3 6.0 0.09 12.8 1.9 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 KND87776.1 - 0.00053 19.9 10.1 0.11 12.6 0.6 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 KND87776.1 - 0.041 14.2 8.4 4.4 7.7 4.6 2.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 KND87776.1 - 3.8 7.3 11.5 12 5.7 6.0 2.4 1 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) TMEM154 PF15102.6 KND87777.1 - 0.0028 17.6 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family PCI PF01399.27 KND87778.1 - 3.8e-23 82.0 0.3 2e-22 79.7 0.1 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KND87778.1 - 2e-16 59.8 2.9 4.7e-16 58.6 2.9 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 KND87779.1 - 1.5e-52 178.4 0.0 1.6e-51 175.0 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 KND87779.1 - 0.015 14.6 0.0 0.049 12.9 0.0 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 ATP-synt_J PF04911.12 KND87780.1 - 2.6e-16 58.9 0.2 5.3e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.13 KND87781.1 - 6.7e-41 138.7 4.0 6.1e-30 103.5 0.1 2.7 3 0 0 3 3 3 2 NIPSNAP Rogdi_lz PF10259.9 KND87782.1 - 3.6e-91 305.3 0.0 4.1e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 KND87783.1 - 3.3e-30 104.8 0.0 4.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KND87783.1 - 2.4e-13 49.7 0.0 5.1e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 Alba Chorion_2 PF03964.15 KND87783.1 - 0.05 14.4 0.6 0.05 14.4 0.6 1.7 2 0 0 2 2 2 0 Chorion family 2 DUF3237 PF11578.8 KND87784.1 - 8.4e-24 84.1 0.0 1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) OST-HTH PF12872.7 KND87784.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Nup84_Nup100 PF04121.13 KND87785.1 - 0.022 12.9 0.0 0.031 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 AIM3 PF17096.5 KND87785.1 - 0.023 15.6 0.0 0.023 15.6 0.0 3.6 4 0 0 4 4 4 0 Altered inheritance of mitochondria protein 3 OPT PF03169.15 KND87786.1 - 5.6e-161 537.2 41.4 6.4e-161 537.1 41.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Flavodoxin_4 PF12682.7 KND87786.1 - 0.031 14.0 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 Flavodoxin Sugar_tr PF00083.24 KND87787.1 - 7.4e-59 199.8 30.3 4.5e-40 137.9 12.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND87787.1 - 8.2e-08 31.6 39.1 0.00017 20.6 13.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KND87788.1 - 2.1e-25 89.4 40.5 8.8e-25 87.4 35.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily M20_dimer PF07687.14 KND87789.1 - 0.014 15.3 0.0 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Peptidase dimerisation domain MF_alpha_N PF05436.11 KND87790.1 - 0.0022 17.9 0.1 0.0045 16.9 0.1 1.5 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus FAD_binding_4 PF01565.23 KND87791.1 - 1.5e-33 115.4 5.6 2.7e-33 114.6 5.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND87791.1 - 1.6e-09 37.7 0.0 8.7e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like ATG22 PF11700.8 KND87792.1 - 1.5e-122 409.6 19.8 1.8e-122 409.4 19.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like ADH_zinc_N PF00107.26 KND87794.1 - 4.2e-21 75.3 0.0 5.8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KND87794.1 - 2e-17 63.1 0.2 3.9e-17 62.1 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KND87794.1 - 5.4e-08 34.0 0.0 1e-07 33.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF469 PF04320.14 KND87794.1 - 0.062 14.2 0.0 11 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein with unknown function (DUF469) p450 PF00067.22 KND87796.1 - 1.1e-15 57.4 0.0 1.3e-06 27.4 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 Epimerase PF01370.21 KND87797.1 - 1.4e-11 44.4 0.0 2.2e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND87797.1 - 3.4e-08 33.6 0.1 2.2e-07 30.9 0.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KND87797.1 - 0.0073 15.7 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KND87797.1 - 0.087 11.9 0.5 11 5.0 0.1 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain Alginate_lyase2 PF08787.11 KND87798.1 - 5.2e-43 147.6 0.0 6e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 KND87798.1 - 0.1 12.4 0.3 0.54 10.1 0.3 2.1 1 1 0 1 1 1 0 Polysaccharide lyase DUF3762 PF12591.8 KND87799.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) PS_Dcarbxylase PF02666.15 KND87800.1 - 3.9e-48 163.7 0.0 5e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Baculo_8kDa PF06096.11 KND87800.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein EBP PF05241.12 KND87801.1 - 9.5e-53 178.3 3.8 1.2e-52 178.0 3.8 1.1 1 0 0 1 1 1 1 Emopamil binding protein TetR_C_33 PF13305.6 KND87801.1 - 0.00016 22.4 0.4 0.0004 21.1 0.4 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain TetR_C_30 PF17939.1 KND87801.1 - 0.00098 19.3 0.2 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain ERG4_ERG24 PF01222.17 KND87802.1 - 3e-150 500.8 3.1 3.4e-150 500.6 3.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KND87802.1 - 0.0021 17.7 0.2 0.0021 17.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PRP38 PF03371.15 KND87804.1 - 4.4e-55 186.2 0.0 5.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 KND87804.1 - 0.0065 17.1 9.8 0.0065 17.1 9.8 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Amidase PF01425.21 KND87805.1 - 5e-113 378.4 0.0 7.7e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 Amidase SIP1 PF04938.12 KND87806.1 - 9.2e-10 38.6 0.0 3e-07 30.4 0.0 2.9 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) CPSase_L_D3 PF02787.19 KND87806.1 - 0.21 11.9 0.2 0.4 11.0 0.2 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SAPS PF04499.15 KND87806.1 - 0.57 8.9 2.2 6.1 5.5 2.9 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 KND87806.1 - 8 5.8 15.0 8.6 5.7 13.3 1.8 2 0 0 2 2 2 0 SDA1 RNR_inhib PF08591.10 KND87807.1 - 2.8e-30 105.8 0.5 7e-30 104.5 0.0 2.0 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.17 KND87808.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 KND87808.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.16 KND87809.1 - 1.4e-10 40.5 0.0 2.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KND87809.1 - 0.0093 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin LRR_4 PF12799.7 KND87810.1 - 5.8e-09 36.1 6.3 6.1e-07 29.7 2.1 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND87810.1 - 3.2e-08 33.2 0.9 3.2e-08 33.2 0.9 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 KND87810.1 - 0.084 13.5 3.8 17 6.4 0.1 3.8 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 KND87810.1 - 0.19 11.9 4.4 2.3 8.5 0.6 2.7 2 0 0 2 2 2 0 Leucine Rich repeat COX16 PF14138.6 KND87811.1 - 2e-31 108.3 0.1 3.5e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 adh_short PF00106.25 KND87811.1 - 3.1e-07 30.0 0.0 1.7e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND87811.1 - 0.00037 20.1 0.0 0.0024 17.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND87811.1 - 0.016 15.1 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 KR domain UL42 PF17638.2 KND87813.1 - 1.5 8.8 5.0 3.7 7.5 5.0 1.7 1 0 0 1 1 1 0 HCMV UL42 EST1_DNA_bind PF10373.9 KND87814.1 - 3e-15 56.4 0.1 6.8e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain zf_C2H2_10 PF18414.1 KND87814.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger ThiF PF00899.21 KND87815.1 - 8.6e-40 136.6 0.0 1.4e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KND87815.1 - 0.00053 20.3 0.1 0.0017 18.6 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KND87815.1 - 0.0095 16.2 0.9 0.024 14.9 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 KND87815.1 - 0.013 16.0 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Melibiase_2 PF16499.5 KND87815.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A UDPG_MGDP_dh_N PF03721.14 KND87815.1 - 0.18 11.4 0.3 0.32 10.5 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-C2H2 PF00096.26 KND87816.1 - 6.3e-09 35.8 12.2 0.00051 20.3 2.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND87816.1 - 1.8e-05 24.9 13.1 3.7e-05 24.0 2.0 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND87816.1 - 7.4e-05 23.3 11.4 0.1 13.5 2.4 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND87816.1 - 0.011 15.7 0.9 0.011 15.7 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KND87816.1 - 0.022 15.1 3.7 0.079 13.4 1.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND87816.1 - 0.062 13.6 4.5 0.084 13.2 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KND87816.1 - 0.29 11.3 2.3 3.3 7.9 0.9 2.4 1 1 1 2 2 2 0 Zinc ribbon domain Pox_A_type_inc PF04508.12 KND87817.1 - 0.012 15.4 1.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Not3 PF04065.15 KND87817.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Ead_Ea22 PF13935.6 KND87817.1 - 0.05 14.3 0.1 0.066 13.9 0.1 1.2 1 0 0 1 1 1 0 Ead/Ea22-like protein BLOC1_2 PF10046.9 KND87817.1 - 0.16 12.3 0.8 0.69 10.3 0.4 2.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Spc19 PF08287.11 KND87819.1 - 2e-47 161.0 0.6 3.5e-47 160.2 0.6 1.4 1 0 0 1 1 1 1 Spc19 SH3_1 PF00018.28 KND87820.1 - 3.8e-09 36.0 0.1 6.3e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND87820.1 - 2e-06 27.5 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND87820.1 - 7.8e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain 7TMR-DISM_7TM PF07695.11 KND87820.1 - 0.32 10.9 11.0 0.44 10.4 11.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4131 PF13567.6 KND87820.1 - 4.3 7.0 6.9 1.9 8.1 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Copper-fist PF00649.18 KND87821.1 - 2.7e-17 61.9 2.6 2.7e-17 61.9 2.6 1.8 1 1 0 1 1 1 1 Copper fist DNA binding domain RGS12_us2 PF16611.5 KND87821.1 - 0.0092 16.4 0.1 0.0092 16.4 0.1 1.6 2 0 0 2 2 2 1 Unstructured region between RBD and GoLoco Ank_2 PF12796.7 KND87822.1 - 1.2e-95 314.3 0.6 1.6e-19 70.3 0.1 8.2 5 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND87822.1 - 4.8e-70 223.1 0.0 0.00029 21.0 0.0 15.4 16 0 0 16 16 14 12 Ankyrin repeat Ank_4 PF13637.6 KND87822.1 - 2.9e-68 225.4 0.2 9.8e-11 42.0 0.0 11.0 4 1 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 KND87822.1 - 7.2e-67 219.1 0.0 1.9e-05 24.9 0.0 14.1 13 1 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 KND87822.1 - 2.2e-55 184.0 0.7 4.3e-09 36.4 0.1 9.3 7 2 0 9 9 9 6 Ankyrin repeats (many copies) NACHT PF05729.12 KND87822.1 - 1.4e-09 38.1 0.1 1.3e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KND87822.1 - 3.8e-05 24.1 0.3 0.00031 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND87822.1 - 0.00015 22.1 0.1 0.00092 19.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KND87822.1 - 0.027 14.9 0.0 0.38 11.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) VWA_3_C PF18571.1 KND87822.1 - 3.7 7.5 14.8 22 5.0 0.0 7.3 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain KAP_NTPase PF07693.14 KND87822.1 - 5.5 6.1 7.2 13 4.9 0.9 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Ribosomal_S16 PF00886.19 KND87823.1 - 2.7e-18 65.8 0.1 3.2e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KND87824.1 - 2.3e-22 79.7 0.0 9.2e-22 77.7 0.0 2.0 2 1 0 2 2 2 1 YjeF-related protein N-terminus ABC_sub_bind PF04392.12 KND87824.1 - 0.19 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein Dynactin_p22 PF07426.11 KND87825.1 - 4.7e-07 29.8 0.0 9.1e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 Dynactin subunit p22 Aa_trans PF01490.18 KND87826.1 - 2.2e-69 234.2 8.6 6.1e-42 143.8 8.3 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KND87826.1 - 0.00083 18.5 5.9 0.00083 18.5 5.9 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Tgi2PP PF18250.1 KND87827.1 - 0.02 15.1 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP BCIP PF13862.6 KND87830.1 - 1.2e-67 227.8 0.1 1.5e-67 227.4 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF2597 PF10772.9 KND87830.1 - 0.015 15.4 0.3 0.078 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) Sec34 PF04136.15 KND87832.1 - 0.035 14.0 2.6 0.57 10.1 0.2 2.4 2 0 0 2 2 2 0 Sec34-like family bZIP_1 PF00170.21 KND87832.1 - 0.039 14.1 10.4 1.1 9.4 0.6 2.8 2 0 0 2 2 2 0 bZIP transcription factor Fib_alpha PF08702.10 KND87832.1 - 0.044 14.0 0.5 0.13 12.5 0.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec20 PF03908.13 KND87832.1 - 0.044 13.7 1.6 0.066 13.1 0.2 2.0 2 0 0 2 2 2 0 Sec20 DUF3086 PF11285.8 KND87832.1 - 0.069 12.2 1.5 0.13 11.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) KASH_CCD PF14662.6 KND87832.1 - 0.18 11.6 7.6 0.51 10.1 7.6 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 KND87832.1 - 0.25 11.4 11.0 3.2 7.8 0.8 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 KND87832.1 - 0.38 10.7 11.3 2 8.3 6.1 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain GAS PF13851.6 KND87832.1 - 0.41 10.0 13.4 0.14 11.5 6.0 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding betaPIX_CC PF16523.5 KND87832.1 - 0.49 10.3 5.5 9.8 6.1 0.1 2.5 2 0 0 2 2 2 0 betaPIX coiled coil V_ATPase_I PF01496.19 KND87832.1 - 0.54 8.1 2.6 0.85 7.5 2.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 KND87832.1 - 0.9 8.4 2.1 1.3 7.9 2.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 KND87832.1 - 1.1 10.0 9.7 6 7.6 2.6 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF4446 PF14584.6 KND87832.1 - 1.1 9.2 6.0 0.84 9.6 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SlyX PF04102.12 KND87832.1 - 1.1 9.9 10.1 0.87 10.3 4.0 3.2 3 0 0 3 3 3 0 SlyX SHE3 PF17078.5 KND87832.1 - 2.8 7.6 8.8 6.4 6.4 2.3 2.3 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4201 PF13870.6 KND87832.1 - 3.1 7.5 12.2 7.9 6.2 5.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-Q PF13094.6 KND87832.1 - 3.4 7.8 23.2 0.16 12.1 5.9 3.7 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit FlaC_arch PF05377.11 KND87832.1 - 4 7.9 4.6 9.3 6.7 0.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KND87832.1 - 7.6 6.4 12.6 9.6 6.1 7.7 2.5 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.11 KND87832.1 - 8.3 6.7 9.2 14 5.9 2.6 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MFS_1 PF07690.16 KND87833.1 - 5.9e-28 97.8 21.9 2.6e-25 89.1 17.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DnaA_N PF11638.8 KND87833.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 DnaA N-terminal domain CDC37_N PF03234.14 KND87837.1 - 1.9e-42 145.2 0.3 1.9e-42 145.2 0.3 2.9 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding Cupin_8 PF13621.6 KND87837.1 - 1.1e-28 100.6 0.0 2.7e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain CDC37_M PF08565.11 KND87837.1 - 4e-28 97.7 3.4 1.4e-27 96.0 1.1 2.5 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain WD40 PF00400.32 KND87837.1 - 1.1e-25 89.3 9.5 2.2e-05 25.1 0.9 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat CDC37_C PF08564.10 KND87837.1 - 3.5e-17 62.4 7.0 2.7e-16 59.5 0.0 2.9 2 0 0 2 2 2 1 Cdc37 C terminal domain ANAPC4_WD40 PF12894.7 KND87837.1 - 1.3e-06 28.6 0.1 0.2 12.0 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND87837.1 - 7.5e-06 24.9 3.4 0.28 9.8 0.0 4.8 3 1 2 5 5 5 2 Nucleoporin Nup120/160 JmjC PF02373.22 KND87837.1 - 2.4e-05 24.7 0.2 0.00011 22.6 0.0 2.2 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KND87837.1 - 0.00013 21.6 0.0 0.0069 15.9 0.0 3.1 3 0 0 3 3 3 1 Cupin superfamily protein TFA2_Winged_2 PF18121.1 KND87837.1 - 0.06 13.0 0.2 0.42 10.3 0.2 2.4 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Cupin_2 PF07883.11 KND87837.1 - 0.11 12.2 0.1 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain APH PF01636.23 KND87838.1 - 0.00014 21.8 2.3 0.00032 20.7 1.7 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Iso_dh PF00180.20 KND87839.1 - 1.2e-96 323.9 0.0 1.4e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KND87839.1 - 0.036 13.9 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 KND87839.1 - 0.1 12.7 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.6 KND87840.1 - 3.4e-37 128.1 0.0 2.6e-36 125.2 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 KND87840.1 - 9.2e-05 22.5 1.8 0.0007 19.6 0.0 3.1 3 0 0 3 3 3 1 Vps51/Vps67 Sec15 PF04091.12 KND87840.1 - 0.0078 15.7 0.3 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like RasGAP_C PF03836.15 KND87840.1 - 7.4 6.7 6.8 5.2 7.2 0.3 3.4 3 0 0 3 3 3 0 RasGAP C-terminus MFS_1 PF07690.16 KND87841.1 - 5.4e-46 157.1 34.2 5.4e-46 157.1 34.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87841.1 - 1.4e-06 27.4 25.4 2.7e-06 26.5 25.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Transglut_core PF01841.19 KND87842.1 - 1.1e-10 41.9 0.0 2.5e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 KND87842.1 - 0.093 13.8 0.0 0.37 11.8 0.0 2.2 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase F-box-like PF12937.7 KND87843.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Seryl_tRNA_N PF02403.22 KND87843.1 - 0.023 14.9 2.0 3.6 7.9 0.2 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.8 KND87843.1 - 0.14 11.8 0.3 0.33 10.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF948 PF06103.11 KND87843.1 - 0.24 11.7 0.6 38 4.6 0.2 2.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) F-box-like PF12937.7 KND87844.1 - 0.0016 18.2 1.2 0.0058 16.5 1.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND87844.1 - 0.033 14.1 1.0 0.071 13.0 1.0 1.6 1 0 0 1 1 1 0 F-box domain Acetyltransf_9 PF13527.7 KND87846.1 - 0.22 11.6 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1_DerP2_DerF2 PF02221.15 KND87847.1 - 1.1e-23 84.2 0.5 2.8e-23 82.8 0.5 1.6 1 1 0 1 1 1 1 ML domain PHD PF00628.29 KND87848.1 - 1.7e-07 31.0 8.8 1.7e-07 31.0 8.8 1.8 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 KND87848.1 - 1e-05 26.0 0.0 4.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 SET domain Glycos_transf_4 PF00953.21 KND87849.1 - 2.4e-29 102.4 8.6 2.4e-29 102.4 8.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2107 PF09880.9 KND87849.1 - 3.6 7.8 8.5 0.61 10.2 0.3 3.3 4 0 0 4 4 4 0 Predicted membrane protein (DUF2107) FAD_binding_4 PF01565.23 KND87850.1 - 2.9e-22 78.9 0.7 8.5e-22 77.4 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 KND87850.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF3328 PF11807.8 KND87851.1 - 4e-54 183.7 0.0 5.2e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.6 KND87852.1 - 1.7e-18 67.0 0.0 3.9e-18 65.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87852.1 - 7.6e-06 26.6 0.0 1.5e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87852.1 - 0.00024 21.7 0.0 0.00053 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87852.1 - 0.00044 20.9 0.0 0.0011 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87852.1 - 0.041 13.7 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KND87852.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain CD24 PF14984.6 KND87852.1 - 5.9 7.2 6.1 1 9.6 0.8 2.2 1 1 0 2 2 2 0 CD24 protein DnaJ PF00226.31 KND87853.1 - 0.0011 19.0 0.1 0.0038 17.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Cep57_CLD PF14073.6 KND87853.1 - 0.67 9.9 5.2 5.9 6.9 5.2 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of Cep57 SMC_Nse1 PF07574.13 KND87854.1 - 2.4e-68 229.9 0.1 3.7e-68 229.3 0.1 1.3 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KND87854.1 - 3.6e-13 49.6 7.3 5.4e-13 49.0 7.3 1.3 1 0 0 1 1 1 1 RING-like domain C1_1 PF00130.22 KND87854.1 - 0.22 11.5 7.3 0.042 13.7 2.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 KND87854.1 - 0.24 11.7 6.9 0.1 12.9 2.0 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KND87854.1 - 0.9 9.7 6.8 0.52 10.5 1.9 2.3 1 1 1 2 2 2 0 PHD-zinc-finger like domain Clr2 PF10383.9 KND87855.1 - 4.8e-11 43.6 0.0 3.6e-10 40.8 0.0 2.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 KND87855.1 - 1.6e-05 25.6 3.3 4.6e-05 24.2 3.3 1.8 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 SPRY PF00622.28 KND87856.1 - 0.0001 22.4 0.0 0.0043 17.1 0.0 2.8 3 0 0 3 3 3 1 SPRY domain HTH_Tnp_Tc5 PF03221.16 KND87858.1 - 5e-16 58.5 2.5 4.4e-08 33.0 0.1 4.4 4 1 0 4 4 4 2 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 KND87858.1 - 5.4e-16 58.2 1.4 1.4e-15 56.8 1.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KND87858.1 - 4.5e-06 26.4 0.5 1e-05 25.3 0.5 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KND87858.1 - 0.0034 18.1 3.8 0.0034 18.1 3.8 5.3 6 0 0 6 6 6 1 C2H2-type zinc finger ECH_1 PF00378.20 KND87858.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase zf-C2H2 PF00096.26 KND87858.1 - 0.074 13.5 19.7 0.043 14.3 3.9 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type GATA PF00320.27 KND87860.1 - 1.6e-29 101.2 17.1 1.6e-15 56.4 3.0 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 KND87860.1 - 1.2e-06 27.9 2.9 0.0066 15.9 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KND87860.1 - 7.1e-05 22.9 1.6 0.092 12.8 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 KND87860.1 - 0.00069 19.5 5.9 0.063 13.2 0.9 3.0 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KND87860.1 - 0.0011 19.0 6.9 0.088 12.9 0.1 3.0 3 0 0 3 3 3 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 KND87860.1 - 0.031 14.4 8.6 0.46 10.7 0.7 2.7 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 KND87860.1 - 0.074 13.1 13.9 0.58 10.2 1.0 3.3 1 1 1 3 3 3 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 KND87860.1 - 0.11 12.2 4.1 25 4.7 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain TDP43_N PF18694.1 KND87860.1 - 0.16 11.9 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain eIF-5_eIF-2B PF01873.17 KND87860.1 - 0.16 11.9 4.9 3.6 7.5 0.5 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-Sec23_Sec24 PF04810.15 KND87860.1 - 0.16 12.1 9.0 0.068 13.2 0.8 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger FYVE PF01363.21 KND87860.1 - 0.3 11.3 3.2 14 5.9 0.3 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.6 KND87860.1 - 0.83 9.2 10.3 23 4.5 0.2 4.3 4 0 0 4 4 4 0 zinc-ribbon domain zf-RRN7 PF11781.8 KND87860.1 - 1.1 9.0 11.1 0.083 12.6 0.5 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ADK_lid PF05191.14 KND87860.1 - 4.2 7.4 6.1 4.2 7.4 0.3 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid Ribosomal_L32p PF01783.23 KND87860.1 - 6.7 7.1 10.0 7.4 6.9 1.7 3.9 2 2 0 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_4 PF13717.6 KND87860.1 - 8.7 6.4 6.2 7.5 6.6 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain MFS_1 PF07690.16 KND87861.1 - 9.2e-29 100.5 27.4 9.2e-29 100.5 27.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CPSase_sm_chain PF00988.22 KND87866.1 - 9e-47 158.1 0.0 2.2e-46 156.8 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KND87866.1 - 2.3e-46 158.0 0.0 3.1e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KND87866.1 - 3.5e-05 23.7 0.2 0.002 17.9 0.1 2.4 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 KND87866.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family SAP PF02037.27 KND87867.1 - 5.7e-13 48.3 0.3 9.5e-13 47.6 0.3 1.4 1 0 0 1 1 1 1 SAP domain Flavodoxin_1 PF00258.25 KND87868.1 - 6.6e-30 104.2 0.0 9.7e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 KND87868.1 - 1.1e-28 100.4 0.0 2.6e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KND87868.1 - 5.8e-12 46.2 0.0 1.3e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KND87868.1 - 0.12 12.6 0.0 1.7 8.9 0.0 2.5 2 1 1 3 3 3 0 Flavodoxin domain RRM_1 PF00076.22 KND87869.1 - 2.5e-30 104.1 0.1 1.7e-14 53.4 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND87869.1 - 0.0001 22.3 0.0 0.14 12.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KND87869.1 - 0.00056 19.5 0.0 1.5 8.4 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head PF16208.5 KND87869.1 - 0.012 15.8 3.4 0.022 14.9 3.4 1.4 1 0 0 1 1 1 0 Keratin type II head DUF4783 PF16022.5 KND87869.1 - 0.026 14.7 0.0 0.097 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) ArfGap PF01412.18 KND87870.1 - 6.3e-32 110.1 0.3 1.4e-31 109.0 0.3 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ETF PF01012.21 KND87871.1 - 9.1e-45 152.8 0.5 1.1e-44 152.5 0.5 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RNA_pol_Rpb5_N PF03871.14 KND87871.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain F-box-like PF12937.7 KND87872.1 - 3e-09 36.6 0.0 6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND87872.1 - 6.5e-07 29.1 0.0 2.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 KND87872.1 - 0.0034 17.2 17.1 0.014 15.2 5.4 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif Casc1_N PF15927.5 KND87872.1 - 2.1 8.0 4.5 3.7 7.2 4.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Asp PF00026.23 KND87875.1 - 2.4e-07 30.5 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease EphA2_TM PF14575.6 KND87875.1 - 0.058 14.3 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NICE-1 PF15845.5 KND87875.1 - 0.31 11.8 8.4 0.28 12.0 0.2 2.8 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family ATP-synt_C PF00137.21 KND87876.1 - 9.8e-25 86.7 26.6 3.2e-15 56.2 8.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 KND87876.1 - 0.028 13.7 2.4 0.085 12.2 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 G0-G1_switch_2 PF15103.6 KND87876.1 - 0.13 12.6 2.7 2 8.9 0.0 2.7 2 1 1 3 3 3 0 G0/G1 switch protein 2 DUF3671 PF12420.8 KND87876.1 - 0.27 11.3 1.8 1.3 9.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function Cation_efflux PF01545.21 KND87876.1 - 0.58 9.9 10.4 4.3 7.0 0.1 2.3 2 1 0 2 2 2 0 Cation efflux family RNase_P_Rpp14 PF01900.19 KND87878.1 - 1.8e-38 130.9 0.0 2.5e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family MoCF_biosynth PF00994.24 KND87879.1 - 1.8e-53 180.1 0.2 1.9e-27 95.7 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KND87879.1 - 2.1e-39 134.8 3.3 3.8e-39 134.0 3.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KND87879.1 - 3.6e-14 52.7 0.0 1.3e-13 50.9 0.0 2.1 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Voltage_CLC PF00654.20 KND87880.1 - 1.5e-87 294.2 27.3 1.5e-87 294.2 27.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KND87880.1 - 4.1e-14 52.8 0.1 2.9e-06 27.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain TFIIA_gamma_C PF02751.14 KND87882.1 - 1.3e-24 86.1 1.1 2e-24 85.5 1.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KND87882.1 - 3.1e-24 84.7 0.3 4.2e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain EamA PF00892.20 KND87883.1 - 0.0013 18.9 15.7 0.0089 16.2 15.7 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KND87883.1 - 0.012 15.6 1.9 0.016 15.3 1.9 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Pkinase PF00069.25 KND87884.1 - 2.8e-05 23.6 0.1 3.3e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND87884.1 - 0.0015 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family VASt PF16016.5 KND87885.1 - 1.6e-36 126.1 0.0 2.4e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KND87885.1 - 2.9e-23 81.9 0.0 4.6e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 GRAM domain adh_short PF00106.25 KND87886.1 - 4.2e-84 280.9 9.4 1.8e-43 148.3 1.6 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND87886.1 - 9.9e-67 224.9 8.6 1.2e-35 123.1 1.7 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KND87886.1 - 1.5e-32 111.8 0.0 3.3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KND87886.1 - 3e-26 92.4 4.6 1.7e-12 47.7 0.5 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 KND87886.1 - 0.00039 19.8 0.6 0.0042 16.4 0.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KND87886.1 - 0.024 14.8 0.0 14 5.8 0.0 2.9 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase SoxE PF06525.11 KND87886.1 - 0.061 12.8 0.0 31 4.0 0.0 3.2 3 0 0 3 3 3 0 Sulfocyanin (SoxE) domain DUF543 PF04418.12 KND87886.1 - 5.1 7.2 9.6 10 6.2 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Methyltransf_23 PF13489.6 KND87887.1 - 1.9e-14 53.8 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87887.1 - 1e-12 48.5 0.0 1.6e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87887.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87887.1 - 3.3e-08 34.1 0.0 5.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87887.1 - 9.1e-07 28.8 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KND87887.1 - 0.001 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KND87887.1 - 0.0025 17.2 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 KND87887.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family ACPS PF01648.20 KND87888.1 - 1.8e-08 34.5 0.6 3.6e-08 33.5 0.6 1.7 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KND87888.1 - 0.0026 17.9 5.7 0.61 10.2 0.8 2.7 2 1 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain AAA_6 PF12774.7 KND87890.1 - 9.5e-127 422.5 0.0 3.6e-126 420.6 0.0 2.1 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KND87890.1 - 4.3e-117 391.6 4.6 4.3e-117 391.6 4.6 5.6 6 1 1 7 7 7 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 KND87890.1 - 1.3e-116 390.5 0.9 1.3e-116 390.5 0.9 4.7 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 KND87890.1 - 1.8e-74 249.6 1.7 1.8e-74 249.6 1.7 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 KND87890.1 - 1.8e-65 220.9 0.0 9.1e-65 218.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KND87890.1 - 1.8e-41 141.7 0.0 8.6e-36 123.1 0.0 4.8 6 0 0 6 6 5 2 P-loop containing dynein motor region MT PF12777.7 KND87890.1 - 5.6e-38 130.8 10.7 1.3e-37 129.6 10.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KND87890.1 - 2.5e-31 108.5 0.0 7.7e-12 45.4 0.0 6.6 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KND87890.1 - 2.5e-29 101.8 0.3 7.9e-27 93.7 0.0 4.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KND87890.1 - 5.5e-28 97.8 0.0 1.4e-27 96.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 KND87890.1 - 3.1e-13 49.9 0.0 1.5e-12 47.7 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KND87890.1 - 4.2e-13 49.8 8.4 0.0097 16.2 0.0 6.9 6 1 1 7 7 6 3 AAA domain AAA PF00004.29 KND87890.1 - 4.2e-13 49.9 0.0 0.0031 17.9 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND87890.1 - 5e-11 43.3 0.4 1.8 8.9 0.0 7.7 8 0 0 8 8 6 2 AAA ATPase domain AAA_33 PF13671.6 KND87890.1 - 6.2e-10 39.4 0.8 0.32 11.2 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 KND87890.1 - 2.2e-09 38.0 0.5 0.087 13.4 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_lid_1 PF17857.1 KND87890.1 - 6.6e-06 26.3 0.4 0.00025 21.2 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_29 PF13555.6 KND87890.1 - 1e-05 25.2 0.1 0.7 9.7 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 KND87890.1 - 6.1e-05 22.2 0.0 0.041 13.0 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KND87890.1 - 0.00019 20.9 1.0 0.67 9.3 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KND87890.1 - 0.0003 21.3 1.5 7.5 7.1 0.0 4.9 4 0 0 4 4 3 0 ABC transporter Taxilin PF09728.9 KND87890.1 - 0.00069 18.9 1.2 0.00069 18.9 1.2 3.9 3 0 0 3 3 2 1 Myosin-like coiled-coil protein AAA_19 PF13245.6 KND87890.1 - 0.00098 19.5 1.0 0.28 11.5 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 KND87890.1 - 0.0014 18.3 1.4 38 3.9 0.0 5.2 6 0 0 6 6 5 0 AAA domain BRE1 PF08647.11 KND87890.1 - 0.0021 18.1 3.5 0.0021 18.1 3.5 5.0 4 0 0 4 4 3 1 BRE1 E3 ubiquitin ligase AAA_24 PF13479.6 KND87890.1 - 0.0028 17.4 0.2 11 5.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain APG6_N PF17675.1 KND87890.1 - 0.0032 18.0 1.2 0.0032 18.0 1.2 5.2 5 0 0 5 5 2 1 Apg6 coiled-coil region AAA_25 PF13481.6 KND87890.1 - 0.0036 16.9 1.0 0.21 11.1 0.0 3.5 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KND87890.1 - 0.0042 16.5 2.3 2.4 7.5 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family Pil1 PF13805.6 KND87890.1 - 0.0057 16.2 0.5 0.0057 16.2 0.5 2.6 2 0 0 2 2 2 1 Eisosome component PIL1 IstB_IS21 PF01695.17 KND87890.1 - 0.0057 16.4 0.6 0.72 9.6 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 KND87890.1 - 0.013 14.8 0.1 7.9 5.7 0.0 4.0 4 0 0 4 4 4 0 Zeta toxin RNA_helicase PF00910.22 KND87890.1 - 0.014 15.8 0.1 44 4.5 0.0 4.6 4 0 0 4 4 4 0 RNA helicase DUF4482 PF14818.6 KND87890.1 - 0.046 14.6 8.4 26 5.7 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Rad17 PF03215.15 KND87890.1 - 0.056 13.4 0.1 6.8 6.6 0.0 3.5 4 0 0 4 4 2 0 Rad17 P-loop domain NACHT PF05729.12 KND87890.1 - 0.91 9.4 5.2 31 4.4 0.0 4.2 4 0 0 4 4 3 0 NACHT domain FUSC PF04632.12 KND87890.1 - 6.9 5.1 10.5 21 3.4 3.7 4.1 4 0 0 4 4 4 0 Fusaric acid resistance protein family CLZ PF16526.5 KND87890.1 - 8.3 6.8 16.3 0.029 14.7 2.3 4.4 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 KND87890.1 - 9.3 4.7 20.6 1.3 7.5 0.6 3.9 3 0 0 3 3 3 0 Flagellar Assembly Protein A DUF1774 PF08611.10 KND87891.1 - 1e-35 121.9 5.0 1e-35 121.9 5.0 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Collagen PF01391.18 KND87893.1 - 0.0001 22.0 11.9 0.0001 22.0 11.9 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) FAR1 PF03101.15 KND87893.1 - 0.0066 17.1 0.0 0.027 15.1 0.0 2.0 1 0 0 1 1 1 1 FAR1 DNA-binding domain Fungal_trans PF04082.18 KND87894.1 - 9.5e-18 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND87894.1 - 1.2e-09 38.1 9.6 2.1e-09 37.3 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5337 PF17272.2 KND87895.1 - 0.53 10.2 3.0 1.2 9.0 3.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 KND87895.1 - 2.2 7.9 16.6 12 5.5 5.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MitMem_reg PF13012.6 KND87896.1 - 7.9e-10 39.1 0.9 1.5e-09 38.2 0.9 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KND87896.1 - 5.6e-07 29.5 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Vps5 PF09325.10 KND87897.1 - 1.4e-12 47.7 1.0 2e-12 47.2 1.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KND87897.1 - 1.1e-09 38.2 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 KND87897.1 - 0.0076 16.5 0.6 0.065 13.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat NST1 PF13945.6 KND87897.1 - 0.06 13.4 2.9 0.12 12.4 2.9 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Aconitase PF00330.20 KND87898.1 - 6.7e-155 516.6 0.0 8.2e-155 516.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KND87898.1 - 5.1e-41 140.1 0.0 1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain EF-hand_7 PF13499.6 KND87899.1 - 4.8e-25 87.8 8.9 4.4e-16 59.1 1.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KND87899.1 - 4.8e-25 85.2 13.9 2.2e-08 33.1 0.2 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KND87899.1 - 5.4e-25 85.2 5.1 1.7e-06 27.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 KND87899.1 - 1.1e-17 62.7 13.8 3.5e-05 23.1 0.1 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 KND87899.1 - 3.8e-14 52.3 12.9 2.2e-05 24.2 1.1 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KND87899.1 - 3.1e-09 36.7 8.6 0.0052 16.7 0.3 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KND87899.1 - 4.2e-05 23.8 1.0 0.0051 17.1 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KND87899.1 - 0.00064 20.0 3.7 0.8 10.0 0.5 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KND87899.1 - 0.013 14.4 0.7 1.7 7.4 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Staphylokinase PF02821.16 KND87899.1 - 0.024 15.0 0.0 5.5 7.4 0.0 2.5 1 1 1 2 2 2 0 Staphylokinase/Streptokinase family EF-hand_10 PF14788.6 KND87899.1 - 0.034 14.0 3.6 0.44 10.4 0.1 3.6 5 0 0 5 5 5 0 EF hand EF-hand_2 PF09068.11 KND87899.1 - 0.15 12.2 0.1 4.1 7.6 0.0 2.8 3 1 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 KND87899.1 - 0.18 12.1 3.3 5.7 7.4 0.0 3.5 3 1 0 3 3 3 0 EF-hand domain Caleosin PF05042.13 KND87899.1 - 0.38 10.7 3.9 31 4.4 0.0 3.5 2 1 2 4 4 4 0 Caleosin related protein CDC45 PF02724.14 KND87900.1 - 3.2e-241 802.1 1.3 2.5e-239 795.8 1.3 3.6 1 1 0 1 1 1 1 CDC45-like protein Pinin_SDK_N PF04697.13 KND87900.1 - 0.0044 17.7 17.0 0.074 13.7 6.3 2.4 2 0 0 2 2 2 2 pinin/SDK conserved region Methyltransf_23 PF13489.6 KND87901.1 - 5.4e-11 42.6 0.0 8.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND87901.1 - 2e-07 31.6 0.0 4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND87901.1 - 8.8e-07 29.6 0.0 5.6e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND87901.1 - 1.1e-06 29.2 0.0 1.8e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87901.1 - 1.5e-05 24.8 0.0 0.19 11.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 KND87901.1 - 0.0095 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 KND87901.1 - 0.018 14.6 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KND87901.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KND87901.1 - 0.074 12.5 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DUF2418 PF10332.9 KND87902.1 - 5e-37 126.3 0.1 1.1e-36 125.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) SesA PF17107.5 KND87903.1 - 0.052 13.7 2.6 0.12 12.5 2.6 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Enkurin PF13864.6 KND87903.1 - 2.9 8.4 8.2 12 6.4 6.6 2.6 3 0 0 3 3 3 0 Calmodulin-binding Gly_transf_sug PF04488.15 KND87904.1 - 1.4e-07 32.0 0.0 3.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KND87904.1 - 0.0072 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain DUF3425 PF11905.8 KND87905.1 - 3.1e-13 49.8 2.2 1e-11 44.9 2.2 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 KND87905.1 - 0.4 10.8 6.4 0.68 10.1 6.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper GTP_EFTU PF00009.27 KND87906.1 - 8.5e-65 217.9 0.2 1.2e-64 217.4 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KND87906.1 - 1.2e-32 112.2 0.0 4.7e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 KND87906.1 - 1.1e-13 51.4 0.0 4.3e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KND87906.1 - 2.8e-12 46.5 0.1 1.2e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KND87906.1 - 5.5e-12 45.6 0.6 8.6e-06 25.7 0.1 2.9 2 1 1 3 3 3 2 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KND87906.1 - 0.0013 18.8 0.2 0.0025 17.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAD_M PF08527.10 KND87906.1 - 0.077 12.6 0.1 0.24 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain FAST_1 PF06743.15 KND87906.1 - 0.1 12.5 0.0 1.8 8.6 0.1 2.3 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 PduV-EutP PF10662.9 KND87906.1 - 0.14 11.9 0.2 0.52 10.1 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MTHFR PF02219.17 KND87908.1 - 2.3e-112 375.0 0.0 3.8e-112 374.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Nup35_RRM_2 PF14605.6 KND87909.1 - 1.2e-07 31.6 0.0 0.00034 20.5 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KND87909.1 - 3.1e-07 30.1 0.2 4.6e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KND87909.1 - 3.3e-05 24.1 0.0 6.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KND87909.1 - 5.1e-05 23.1 4.0 9.6e-05 22.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_occluded PF16842.5 KND87909.1 - 0.0033 17.3 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 KND87909.1 - 0.036 14.6 1.3 0.059 13.9 1.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF1330 PF07045.11 KND87909.1 - 0.062 13.6 0.1 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) zf_CCCH_4 PF18345.1 KND87909.1 - 0.073 13.2 3.8 0.14 12.2 3.8 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF5401 PF17380.2 KND87909.1 - 2.6 6.0 13.0 3.9 5.4 13.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) OmpH PF03938.14 KND87909.1 - 7.2 7.0 14.0 17 5.8 14.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3372 PF11852.8 KND87911.1 - 0.079 12.4 0.3 0.23 11.0 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Grp7_allergen PF16984.5 KND87911.1 - 0.14 12.2 0.2 0.24 11.5 0.2 1.2 1 0 0 1 1 1 0 Group 7 allergen zf-C2H2_6 PF13912.6 KND87911.1 - 0.33 11.0 1.3 3.1 7.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 KND87911.1 - 0.84 9.7 4.8 0.31 11.1 0.2 2.3 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.18 KND87911.1 - 1.8 8.8 12.1 0.082 13.0 6.2 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Solute_trans_a PF03619.16 KND87912.1 - 1.1e-100 336.5 8.6 1.3e-100 336.3 8.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.12 KND87913.1 - 1.9e-136 455.7 0.5 2.2e-136 455.5 0.0 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KND87913.1 - 3.3e-46 158.1 4.5 5.3e-46 157.5 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Zip PF02535.22 KND87914.1 - 3e-54 184.5 7.8 1.1e-53 182.6 7.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_17 PF00332.18 KND87915.1 - 1.2e-07 31.7 0.1 2.1e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.12 KND87916.1 - 2.6e-26 92.6 34.3 8.6e-25 87.5 34.3 3.2 1 1 0 1 1 1 1 Hamartin protein Sec7_N PF12783.7 KND87916.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Tuberin PF03542.16 KND87916.1 - 0.12 11.5 0.2 0.25 10.4 0.2 1.5 1 0 0 1 1 1 0 Tuberin FlaC_arch PF05377.11 KND87916.1 - 1 9.8 6.2 25 5.4 0.1 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KND87916.1 - 2.5 7.4 26.0 2.5 7.4 1.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 KND87916.1 - 7.7 4.9 40.2 28 3.1 40.2 1.8 1 1 0 1 1 1 0 Macoilin family DJ-1_PfpI PF01965.24 KND87917.1 - 1.8e-12 47.4 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KND87917.1 - 6.1e-05 22.8 0.0 8.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 KND87917.1 - 0.065 13.1 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family GATase_5 PF13507.6 KND87917.1 - 0.11 11.5 0.1 0.51 9.4 0.1 1.8 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pyridoxal_deC PF00282.19 KND87918.1 - 7.5e-102 340.8 0.0 9.1e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain EMP70 PF02990.16 KND87919.1 - 1.1e-187 624.9 0.0 1.3e-174 581.8 0.0 2.1 1 1 1 2 2 2 2 Endomembrane protein 70 EPV_E5 PF08135.11 KND87919.1 - 7 7.1 9.7 1.3 9.5 2.9 3.0 2 0 0 2 2 2 0 Major transforming protein E5 family Bul1_C PF04426.12 KND87920.1 - 4e-05 23.2 0.0 0.00011 21.7 0.0 1.7 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.12 KND87920.1 - 0.0075 15.1 0.0 0.097 11.4 0.0 2.2 2 0 0 2 2 2 1 Bul1 N terminus Arrestin_C PF02752.22 KND87920.1 - 0.062 13.7 0.1 0.83 10.1 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Phospholip_A2_3 PF09056.11 KND87921.1 - 2.6e-35 121.4 1.5 3.2e-35 121.1 1.5 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 ATP_bind_1 PF03029.17 KND87922.1 - 8.4e-79 264.8 0.0 1.2e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KND87922.1 - 0.0058 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 KND87922.1 - 0.017 14.4 0.1 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 KND87922.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KND87922.1 - 0.046 13.9 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KND87922.1 - 0.048 13.6 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 KND87923.1 - 9.8e-31 105.7 0.2 2.5e-16 59.5 0.0 5.5 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KND87923.1 - 2.8e-16 60.3 5.5 2.8e-15 57.1 5.5 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase YqhR PF11085.8 KND87923.1 - 1.3 8.9 7.4 3.3 7.6 6.5 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR MFS_1 PF07690.16 KND87924.1 - 6.7e-39 133.8 35.5 6.7e-39 133.8 35.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND87924.1 - 9.5e-13 47.8 5.3 9.5e-13 47.8 5.3 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KND87924.1 - 0.1 11.0 7.7 0.13 10.6 0.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector ATP-synt_DE_N PF02823.16 KND87926.1 - 1.1e-15 57.3 0.1 1.8e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.9 KND87927.1 - 3.2e-164 547.5 58.7 2.8e-104 349.9 37.9 4.0 2 2 3 5 5 5 2 Protein of unknown function (DUF2457) Nop14 PF04147.12 KND87927.1 - 0.00051 18.4 19.0 0.00093 17.5 19.0 1.3 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.13 KND87927.1 - 0.00076 19.6 19.1 0.00076 19.6 19.1 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 KND87927.1 - 0.075 12.4 25.5 0.012 15.0 20.1 2.1 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 KND87927.1 - 0.93 7.7 21.1 0.22 9.8 14.9 2.0 2 0 0 2 2 2 0 CDC45-like protein Vfa1 PF08432.10 KND87927.1 - 3.5 7.9 9.2 10 6.4 9.2 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Methyltransf_PK PF05891.12 KND87928.1 - 2.8e-65 219.9 0.1 4.1e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Succ_CoA_lig PF13607.6 KND87928.1 - 0.0021 17.8 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain zf-C3HC4 PF00097.25 KND87929.1 - 0.00011 22.0 5.2 0.00029 20.7 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KND87929.1 - 0.015 15.5 5.2 0.039 14.2 5.2 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KND87929.1 - 0.025 14.4 5.6 0.063 13.1 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KND87929.1 - 0.54 10.4 6.2 0.1 12.8 2.1 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 KND87929.1 - 1.3 9.2 5.1 3.4 7.9 5.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KND87929.1 - 3.3 8.1 11.5 0.27 11.6 6.4 1.9 2 0 0 2 2 2 0 Ring finger domain FeS PF04060.13 KND87929.1 - 7.7 6.3 6.5 0.47 10.1 0.7 2.0 2 0 0 2 2 2 0 Putative Fe-S cluster TolA_bind_tri PF16331.5 KND87930.1 - 0.0042 17.1 6.5 0.0075 16.3 6.5 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation Tmemb_cc2 PF10267.9 KND87930.1 - 0.0045 16.2 0.4 0.0064 15.7 0.4 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Phlebovirus_NSM PF07246.11 KND87930.1 - 0.0059 16.0 3.6 0.0089 15.4 3.6 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M bZIP_2 PF07716.15 KND87930.1 - 0.045 13.8 16.3 0.08 13.0 16.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Fungal_TACC PF12709.7 KND87930.1 - 0.13 12.7 4.3 0.23 11.9 4.3 1.3 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins DASH_Spc19 PF08287.11 KND87930.1 - 0.27 11.1 10.0 0.42 10.5 10.0 1.3 1 0 0 1 1 1 0 Spc19 bZIP_1 PF00170.21 KND87930.1 - 0.37 10.9 14.9 0.56 10.4 14.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor SGL PF08450.12 KND87931.1 - 1.8e-60 204.6 0.0 2.4e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 KND87931.1 - 0.1 12.7 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) Arylesterase PF01731.20 KND87931.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Arylesterase DUF3377 PF11857.8 KND87932.1 - 0.094 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Aldedh PF00171.22 KND87933.1 - 5e-170 566.0 0.0 5.7e-170 565.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Arf PF00025.21 KND87934.1 - 2.5e-66 222.4 0.0 2.9e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KND87934.1 - 7.4e-10 38.5 0.1 2.5e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND87934.1 - 1.2e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND87934.1 - 1.5e-07 31.6 0.0 5.1e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND87934.1 - 3.2e-07 29.9 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KND87934.1 - 3.5e-07 30.3 0.0 4.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND87934.1 - 6.9e-06 25.6 0.0 8.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KND87934.1 - 0.0037 16.8 0.1 0.15 11.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.8 KND87934.1 - 0.045 12.9 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 KND87934.1 - 0.19 11.3 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.28 KND87936.1 - 4e-71 239.8 0.3 3.6e-38 131.3 0.0 4.2 2 2 0 2 2 2 2 AMP-binding enzyme RicinB_lectin_2 PF14200.6 KND87937.1 - 1.1e-06 29.3 6.6 0.00076 20.2 0.6 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.10 KND87937.1 - 2.2e-05 23.8 0.3 4.6e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 KND87937.1 - 0.042 14.0 0.1 0.066 13.4 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Glyco_hydro_31 PF01055.26 KND87938.1 - 1.2e-91 308.2 4.1 1.6e-91 307.8 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KND87938.1 - 0.0044 17.3 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 KND87938.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Sugar_tr PF00083.24 KND87939.1 - 4.2e-60 203.9 5.0 7.9e-57 193.1 6.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND87939.1 - 2.2e-14 53.1 15.5 2.3e-14 53.1 13.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND87939.1 - 0.0097 15.2 3.0 0.0097 15.2 3.0 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB zf-RING_13 PF17977.1 KND87939.1 - 0.75 10.0 4.4 2.2 8.5 1.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Gamma-thionin PF00304.20 KND87940.1 - 0.017 15.4 6.1 0.027 14.7 6.1 1.3 1 0 0 1 1 1 0 Gamma-thionin family Response_reg PF00072.24 KND87941.1 - 1.2e-21 76.9 0.0 3e-15 56.4 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain DUF2052 PF09747.9 KND87942.1 - 5.2e-23 82.2 14.4 2.9e-12 47.1 8.4 2.1 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) pKID PF02173.17 KND87942.1 - 0.12 11.8 0.6 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 pKID domain DUF2052 PF09747.9 KND87943.1 - 5.2e-23 82.2 14.4 2.9e-12 47.1 8.4 2.1 1 1 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) pKID PF02173.17 KND87943.1 - 0.12 11.8 0.6 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 pKID domain Y_phosphatase3 PF13350.6 KND87944.1 - 2.6e-53 181.4 0.0 3.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KND87944.1 - 9.2e-06 25.4 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KND87944.1 - 4.4e-05 23.1 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 KND87944.1 - 0.013 15.4 0.0 0.18 11.6 0.2 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KND87944.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Bot1p PF12298.8 KND87945.1 - 2.1e-51 174.5 3.1 2.1e-51 174.5 3.1 1.8 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein DNA_pol3_a_NII PF11490.8 KND87945.1 - 0.71 9.8 4.2 1.2 9.0 4.2 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II TRAP-gamma PF07074.12 KND87945.1 - 3.5 7.1 5.0 1.1 8.8 2.2 1.5 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) adh_short_C2 PF13561.6 KND87946.1 - 3.5e-47 160.9 1.2 7.1e-33 114.1 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87946.1 - 1.1e-42 145.7 0.0 1.9e-42 144.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND87946.1 - 2.8e-09 37.2 0.2 8.5e-09 35.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KND87946.1 - 0.0011 18.5 0.2 0.015 14.7 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KND87946.1 - 0.0075 15.6 0.0 0.018 14.4 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNase_II_C_S1 PF18614.1 KND87946.1 - 0.12 12.3 2.3 0.2 11.6 0.3 2.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Abhydrolase_6 PF12697.7 KND87947.1 - 1.5e-14 55.2 0.1 4.7e-14 53.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND87947.1 - 0.00053 19.3 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND87947.1 - 0.037 13.7 0.0 0.091 12.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 KND87947.1 - 0.05 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.25 KND87948.1 - 6.2e-17 61.8 0.0 6.6e-16 58.5 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KND87948.1 - 0.086 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 KND87949.1 - 1.7e-11 44.4 0.1 2.5e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND87949.1 - 6.9e-08 32.8 0.4 1.1e-07 32.2 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND87949.1 - 1.3e-07 31.6 0.2 2e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rubredoxin_C PF18267.1 KND87949.1 - 0.1 12.6 0.1 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain PI-PLC-X PF00388.19 KND87950.1 - 1.4e-61 206.3 0.0 2e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KND87950.1 - 5.6e-44 149.2 0.0 9.5e-44 148.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 KND87950.1 - 0.055 14.0 0.0 1 9.9 0.0 2.4 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like VIT1 PF01988.19 KND87951.1 - 0.049 13.5 7.5 0.013 15.3 4.2 1.7 1 1 1 2 2 2 0 VIT family DUF4293 PF14126.6 KND87951.1 - 0.092 13.0 2.6 0.11 12.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) MPS2 PF17060.5 KND87951.1 - 0.35 10.1 1.1 0.43 9.8 1.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4064 PF13273.6 KND87951.1 - 1.9 8.8 9.2 10 6.4 7.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ABC2_membrane_3 PF12698.7 KND87951.1 - 6.1 5.9 9.2 8.2 5.4 9.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.9 KND87951.1 - 8.8 5.0 7.7 2.9 6.5 5.1 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PRIMA1 PF16101.5 KND87952.1 - 0.051 13.6 8.9 0.13 12.3 8.9 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fer4_21 PF14697.6 KND87952.1 - 6.8 6.9 11.3 2.9 8.1 5.6 3.3 4 1 0 4 4 4 0 4Fe-4S dicluster domain Fungal_trans_2 PF11951.8 KND87953.1 - 2.1e-08 33.4 0.0 2.6e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KND87954.1 - 8e-47 159.8 0.1 9.4e-47 159.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND87954.1 - 4.4e-37 127.4 0.1 5.1e-37 127.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND87954.1 - 2e-11 44.1 0.1 2.8e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND87954.1 - 0.0013 18.2 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND87954.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF594 PF04578.13 KND87954.1 - 0.16 11.6 0.1 0.55 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF594 ThiF PF00899.21 KND87954.1 - 0.2 11.0 2.5 0.8 9.0 0.6 2.1 1 1 1 2 2 2 0 ThiF family Med10 PF09748.9 KND87955.1 - 2.1e-47 160.0 0.0 2.6e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF5601 PF18151.1 KND87955.1 - 0.045 14.1 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) TPR_1 PF00515.28 KND87956.1 - 4.7e-39 130.6 11.6 9.7e-08 31.5 0.0 7.8 8 0 0 8 8 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 KND87956.1 - 2.4e-38 127.2 11.9 1e-05 25.2 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 KND87956.1 - 2.9e-31 106.9 7.2 6.8e-09 35.3 0.0 6.8 5 1 1 6 6 6 6 TPR repeat TPR_19 PF14559.6 KND87956.1 - 1.2e-27 96.2 8.5 1.3e-08 35.2 0.0 6.1 3 3 2 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.31 KND87956.1 - 1.1e-26 92.7 2.0 1.1e-26 92.7 2.0 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_16 PF13432.6 KND87956.1 - 8.4e-25 87.2 12.4 9e-09 35.8 1.0 6.8 4 2 3 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KND87956.1 - 1.8e-23 80.7 5.9 0.00013 21.9 0.3 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KND87956.1 - 5.6e-20 70.3 16.5 0.00011 22.7 0.4 8.6 6 2 4 10 10 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KND87956.1 - 4.9e-17 61.0 6.9 0.0039 17.5 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KND87956.1 - 5.9e-17 61.7 0.3 1.3e-05 25.3 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KND87956.1 - 9.6e-17 61.1 9.2 0.0001 22.5 0.1 5.8 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 KND87956.1 - 5.9e-16 58.4 1.7 5.7e-05 23.2 0.1 4.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KND87956.1 - 5.6e-11 42.3 12.4 0.4 11.4 0.2 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KND87956.1 - 1.6e-10 40.3 1.3 0.69 10.1 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KND87956.1 - 2.2e-10 40.2 2.8 0.0018 17.6 0.0 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat BTAD PF03704.17 KND87956.1 - 6.2e-06 26.7 4.9 0.2 12.1 0.0 5.1 3 2 1 5 5 5 1 Bacterial transcriptional activator domain NARP1 PF12569.8 KND87956.1 - 1.8e-05 23.9 0.4 0.01 14.8 0.1 3.4 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KND87956.1 - 2.2e-05 24.2 14.4 1.4 8.9 0.2 7.2 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KND87956.1 - 8.4e-05 22.8 1.2 2.9 8.8 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 KND87956.1 - 0.00011 22.4 3.6 13 6.2 0.0 5.6 3 2 3 7 7 7 0 Tetratricopeptide repeat ChAPs PF09295.10 KND87956.1 - 0.00087 18.4 0.0 0.98 8.3 0.0 2.8 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.18 KND87956.1 - 0.0011 19.0 3.1 0.39 10.8 0.1 4.2 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 KND87956.1 - 0.0012 19.3 3.7 0.88 10.0 0.0 4.0 3 1 1 4 4 4 1 Alkyl sulfatase dimerisation Coatomer_E PF04733.14 KND87956.1 - 0.0016 18.0 0.1 0.92 8.9 0.0 2.9 3 0 0 3 3 3 1 Coatomer epsilon subunit DUF3808 PF10300.9 KND87956.1 - 0.0039 16.0 0.1 0.41 9.3 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3808) DUF3856 PF12968.7 KND87956.1 - 0.0051 16.9 2.2 63 3.6 0.0 5.6 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 KND87956.1 - 0.0055 16.8 3.7 24 5.1 0.0 4.4 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 KND87956.1 - 0.009 15.5 2.6 1.1 8.6 0.0 2.7 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP YfiO PF13525.6 KND87956.1 - 0.048 13.4 0.4 0.16 11.7 0.1 2.0 2 0 0 2 2 1 0 Outer membrane lipoprotein Wzy_C_2 PF11846.8 KND87956.1 - 0.06 13.3 0.1 0.06 13.3 0.1 2.5 2 1 1 3 3 2 0 Virulence factor membrane-bound polymerase, C-terminal SRP_TPR_like PF17004.5 KND87956.1 - 0.23 11.5 1.5 3.7 7.6 0.2 3.2 3 1 0 4 4 3 0 Putative TPR-like repeat DUF3597 PF12200.8 KND87956.1 - 1.9 9.0 6.4 0.22 12.1 0.2 2.6 2 1 0 2 2 1 0 Domain of unknown function (DUF3597) EF-hand_6 PF13405.6 KND87957.1 - 4.5e-12 44.9 0.5 2.3e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KND87957.1 - 1.4e-09 36.8 1.2 0.0016 17.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KND87957.1 - 1.3e-07 32.0 1.4 3e-06 27.6 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KND87957.1 - 8.8e-07 28.7 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KND87957.1 - 1.9e-05 23.9 3.7 0.015 14.8 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KND87957.1 - 0.0037 17.6 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Esterase PF00756.20 KND87958.1 - 3.8e-47 161.0 0.0 4.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KND87958.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KND87958.1 - 0.0084 15.4 0.0 0.019 14.2 0.0 1.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KND87958.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KND87958.1 - 0.023 13.6 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ran_BP1 PF00638.18 KND87959.1 - 6.3e-23 81.3 0.1 1.3e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 RanBP1 domain Arrestin_N PF00339.29 KND87959.1 - 7.3e-09 35.8 0.9 4.1e-08 33.4 0.9 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain bZIP_1 PF00170.21 KND87961.1 - 3.2e-06 27.1 7.1 6.9e-06 26.1 7.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF5595 PF18077.1 KND87961.1 - 0.15 12.2 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 KND87961.1 - 0.35 10.7 3.9 0.68 9.8 3.4 1.6 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 KND87961.1 - 0.53 10.4 8.8 0.81 9.8 7.6 2.0 1 1 0 1 1 1 0 Basic region leucine zipper V-SNARE_C PF12352.8 KND87962.1 - 0.033 14.5 0.2 0.1 12.9 0.2 1.8 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus RIX1 PF08167.12 KND87963.1 - 6.5e-61 205.4 0.0 1e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Glyco_hydro_16 PF00722.21 KND87964.1 - 8.2e-10 38.4 1.5 1.3e-09 37.8 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Xpo1 PF08389.12 KND87965.1 - 1.1e-33 116.4 0.2 1e-32 113.2 0.1 2.8 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 KND87965.1 - 0.0016 18.5 0.0 16 6.1 0.0 4.5 3 0 0 3 3 3 2 HEAT repeat LEA_6 PF10714.9 KND87965.1 - 0.049 13.7 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Prefoldin_2 PF01920.20 KND87965.1 - 0.07 13.1 0.4 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit EF-G-binding_N PF07299.11 KND87965.1 - 0.12 12.9 0.2 3.4 8.3 0.0 3.4 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal TPR_14 PF13428.6 KND87966.1 - 1.5e-09 37.8 27.4 0.074 13.9 0.0 9.3 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND87966.1 - 3.2e-09 36.2 13.6 0.34 11.1 0.0 7.5 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND87966.1 - 1.3e-07 31.1 2.3 1.7 8.6 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND87966.1 - 1.2e-05 25.1 4.9 0.38 11.1 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND87966.1 - 3.2e-05 24.3 11.7 0.2 12.2 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND87966.1 - 5.5e-05 23.3 1.6 0.12 12.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND87966.1 - 0.001 18.9 5.2 4.3 7.6 0.6 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND87966.1 - 0.0017 18.6 16.2 5.7 7.3 0.4 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND87966.1 - 0.1 12.9 4.4 5.4 7.3 0.1 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KND87966.1 - 0.12 13.0 16.8 10 6.9 0.2 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND87966.1 - 0.16 12.1 5.5 0.26 11.4 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND87966.1 - 4.3 8.2 0.0 4.3 8.2 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 KND87967.1 - 4.7e-11 42.7 0.0 2.9e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND87967.1 - 2.8e-09 37.2 0.0 1e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND87967.1 - 8.4e-09 35.7 0.0 1.7e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND87967.1 - 3.8e-05 23.8 0.0 0.00012 22.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KND87967.1 - 0.064 13.4 0.0 0.17 12.1 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KND87967.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF2076 PF09849.9 KND87968.1 - 0.71 9.9 3.2 0.9 9.5 3.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Whi5 PF08528.11 KND87969.1 - 1.1e-09 37.7 0.1 1.8e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Remorin_N PF03766.13 KND87969.1 - 8.7 6.5 10.1 7.5 6.7 1.5 2.8 3 0 0 3 3 3 0 Remorin, N-terminal region Peptidase_M18 PF02127.15 KND87970.1 - 1.7e-172 574.1 0.0 3.2e-172 573.2 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KND87970.1 - 0.0004 19.5 0.0 0.003 16.6 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase DUF2807 PF10988.8 KND87971.1 - 3.5 7.4 9.5 0.19 11.5 0.9 2.6 3 0 0 3 3 3 0 Putative auto-transporter adhesin, head GIN domain ketoacyl-synt PF00109.26 KND87973.1 - 5.8e-61 206.3 0.0 6.8e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 KND87973.1 - 7.1e-07 28.8 0.1 9.7e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KND87973.1 - 0.08 12.8 0.4 0.41 10.5 0.4 2.0 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 KND87974.1 - 1.9e-11 44.1 0.0 3.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND87974.1 - 2.3e-05 24.3 0.6 4.8e-05 23.2 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KND87974.1 - 0.036 14.0 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase AMP-binding PF00501.28 KND87975.1 - 5.1e-80 269.1 0.0 7.8e-80 268.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KND87975.1 - 3.4e-67 227.1 0.0 6.5e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 KND87975.1 - 1.1e-54 185.0 0.2 1.4e-50 171.7 0.0 2.4 2 0 0 2 2 2 2 KR domain PS-DH PF14765.6 KND87975.1 - 5.3e-47 160.5 0.0 8.9e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 KND87975.1 - 8.6e-29 100.5 0.0 1.2e-27 96.7 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KND87975.1 - 5.7e-18 65.0 2.3 2e-08 34.5 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KND87975.1 - 5.2e-17 62.4 0.0 1.6e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 KND87975.1 - 1.4e-15 57.6 0.0 3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_25 PF13649.6 KND87975.1 - 4.4e-12 46.5 0.0 1.6e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KND87975.1 - 8.8e-10 38.4 0.0 4.1e-08 32.9 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KND87975.1 - 9e-10 38.6 0.0 2.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KND87975.1 - 1.9e-09 37.4 0.0 3.5e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 KND87975.1 - 2.6e-09 37.6 0.0 1.2e-08 35.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND87975.1 - 1.2e-05 25.1 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding_C PF13193.6 KND87975.1 - 2.5e-05 25.1 0.1 9.1e-05 23.4 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.17 KND87975.1 - 0.0013 17.9 0.0 0.017 14.2 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain Ubie_methyltran PF01209.18 KND87975.1 - 0.0016 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 KND87975.1 - 0.0018 17.9 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KND87975.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KND87975.1 - 0.028 14.8 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NodS PF05401.11 KND87975.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KND87975.1 - 0.17 11.6 0.0 0.83 9.4 0.0 2.1 1 1 0 1 1 1 0 Lysine methyltransferase Ketoacyl-synt_C PF02801.22 KND87976.1 - 5.8e-31 107.0 0.1 5.8e-31 107.0 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KND87976.1 - 3.7e-22 79.2 0.5 5.4e-22 78.7 0.5 1.2 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KND87976.1 - 6.6e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 KND87976.1 - 5e-06 26.3 0.0 9.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 KND87978.1 - 1.3e-06 27.6 7.7 0.0032 16.4 3.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PDEase_II PF02112.15 KND87983.1 - 4e-50 170.9 0.0 2.5e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KND87983.1 - 0.0039 17.2 0.6 0.02 14.9 0.1 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.18 KND87984.1 - 3.5e-14 53.1 0.0 5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Lactamase_B_2 PF12706.7 KND87985.1 - 1.1e-19 70.8 0.1 2.2e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KND87985.1 - 4.3e-18 64.7 0.0 2e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 tRNase Z endonuclease Pkinase PF00069.25 KND87986.1 - 6.6e-50 169.9 0.0 5.5e-49 166.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND87986.1 - 3.9e-18 65.7 0.0 2.3e-17 63.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KND87986.1 - 0.076 12.0 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mtc PF03820.17 KND87987.1 - 7.2e-114 380.0 0.0 8.3e-114 379.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Acetyltransf_7 PF13508.7 KND87988.1 - 0.00068 20.0 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND87988.1 - 0.0041 17.4 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KND87988.1 - 0.015 15.3 0.0 0.069 13.2 0.0 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Arf PF00025.21 KND87989.1 - 2e-66 222.8 0.4 2.2e-66 222.6 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KND87989.1 - 2.1e-12 46.9 0.9 4.4e-07 29.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND87989.1 - 5.7e-12 45.5 0.0 6.6e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND87989.1 - 7.7e-12 45.5 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND87989.1 - 7e-09 35.4 0.0 8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KND87989.1 - 1.8e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND87989.1 - 1.5e-07 31.5 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND87989.1 - 0.0011 18.5 0.0 0.021 14.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KND87989.1 - 0.041 13.4 0.2 0.083 12.4 0.2 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KND87989.1 - 0.092 12.8 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KND87989.1 - 0.12 12.1 0.1 0.36 10.6 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4045 PF13254.6 KND87990.1 - 1.2e-90 305.1 49.9 2e-51 175.9 29.1 6.7 3 3 2 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 KND87990.1 - 2e-05 24.4 0.0 0.38 10.7 0.0 3.5 3 0 0 3 3 3 2 Gelsolin repeat Pannexin_like PF12534.8 KND87990.1 - 7 5.6 6.2 15 4.5 6.2 1.5 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Acyltransferase PF01553.21 KND87991.1 - 1.6e-33 115.2 0.0 2.9e-33 114.4 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.21 KND87991.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP CbiQ PF02361.16 KND87991.1 - 0.073 12.7 2.9 0.13 11.9 2.9 1.3 1 0 0 1 1 1 0 Cobalt transport protein DUF2347 PF09804.9 KND87992.1 - 2.7e-105 352.0 0.0 3.4e-105 351.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KND87992.1 - 2.7e-65 220.3 0.0 4.6e-65 219.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 KND87992.1 - 0.0018 18.3 0.0 0.0041 17.1 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KND87992.1 - 0.036 12.8 0.0 0.13 10.9 0.0 1.9 2 0 0 2 2 2 0 Transport protein Avl9 Importin_rep_4 PF18808.1 KND87992.1 - 0.15 12.3 0.4 1 9.7 0.2 2.2 2 0 0 2 2 2 0 Importin repeat zf-C2H2 PF00096.26 KND87993.1 - 3e-23 80.9 62.3 0.00015 22.0 3.5 10.6 10 1 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND87993.1 - 2e-18 65.5 61.6 0.0075 17.0 3.2 10.8 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND87993.1 - 4.5e-13 49.0 55.7 0.0031 17.9 0.2 10.6 11 1 0 11 11 10 5 Zinc-finger double domain FOXP-CC PF16159.5 KND87993.1 - 1.5e-08 35.1 34.3 0.007 17.0 0.2 7.2 4 1 2 7 7 7 4 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KND87993.1 - 1.4e-06 28.5 20.5 0.035 14.4 6.7 4.5 2 1 2 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KND87993.1 - 0.00011 22.3 30.1 0.54 10.6 0.2 7.7 9 0 0 9 9 7 3 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KND87993.1 - 0.011 15.5 0.1 0.011 15.5 0.1 8.3 9 1 1 10 10 10 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 KND87993.1 - 0.05 13.5 2.4 9.3 6.3 0.1 3.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KND87993.1 - 0.096 12.2 8.1 1.2 8.7 0.2 3.8 3 0 0 3 3 3 0 TFIIB zinc-binding zf-C2H2_aberr PF17017.5 KND87993.1 - 0.11 12.6 24.8 2.3 8.3 0.5 5.2 3 2 2 5 5 5 0 Aberrant zinc-finger zf-met PF12874.7 KND87993.1 - 0.15 12.5 21.1 0.96 9.9 0.0 6.8 8 0 0 8 8 7 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KND87993.1 - 0.24 11.7 41.7 3.9 7.9 0.0 7.1 5 2 3 8 8 8 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KND87993.1 - 0.74 10.0 0.0 0.74 10.0 0.0 5.5 7 0 0 7 7 6 0 Zic proteins zinc finger domain DZR PF12773.7 KND87993.1 - 1.1 9.3 15.4 64 3.7 0.0 4.0 2 1 0 2 2 2 0 Double zinc ribbon Ogr_Delta PF04606.12 KND87993.1 - 1.3 9.0 9.1 8.4 6.5 0.1 4.2 4 0 0 4 4 4 0 Ogr/Delta-like zinc finger zinc_ribbon_9 PF14369.6 KND87993.1 - 1.6 9.1 0.0 1.6 9.1 0.0 3.7 5 0 0 5 5 3 0 zinc-ribbon zf-C2HC_2 PF13913.6 KND87993.1 - 3.6 7.6 11.1 13 5.8 0.0 5.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 KND87993.1 - 5.4 7.2 21.1 3.4 7.9 3.2 4.7 4 1 1 5 5 4 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.13 KND87993.1 - 6.6 6.5 10.6 2.6 7.9 1.6 3.2 3 0 0 3 3 3 0 InsA N-terminal domain zf_C2H2_ZHX PF18387.1 KND87993.1 - 9.6 5.9 15.5 0.73 9.5 0.5 4.4 4 1 1 5 5 4 0 Zinc-fingers and homeoboxes C2H2 finger domain RNA_pol_Rpb6 PF01192.22 KND87994.1 - 2.8e-17 62.4 0.7 6.7e-17 61.2 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb6 Ligase_CoA PF00549.19 KND87994.1 - 0.12 12.2 1.4 0.25 11.2 0.8 1.8 2 1 0 2 2 2 0 CoA-ligase Tmemb_170 PF10190.9 KND87996.1 - 5.8e-30 103.8 13.4 6.7e-30 103.6 13.4 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 ICMT PF04140.14 KND87997.1 - 5.7e-27 94.0 1.5 7e-27 93.7 0.2 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KND87997.1 - 2.3e-12 47.2 7.1 1e-11 45.1 1.2 2.4 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF1295 PF06966.12 KND87997.1 - 0.00037 20.1 0.2 0.00055 19.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KND87997.1 - 0.00092 18.8 1.2 0.00092 18.8 1.2 2.0 1 1 0 2 2 2 1 NnrU protein MBOAT PF03062.19 KND87998.1 - 2.3e-17 63.4 16.9 3.3e-17 62.9 16.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KND87998.1 - 0.0005 20.3 3.3 0.0018 18.5 3.3 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 KND88000.1 - 4.5e-32 109.6 22.4 2.3e-05 25.1 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88000.1 - 1e-12 48.1 0.0 0.014 15.7 0.0 5.3 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND88000.1 - 0.0013 18.7 0.1 1 9.2 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 KND88000.1 - 0.059 11.7 0.0 0.13 10.6 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Sporozoite_P67 PF05642.11 KND88000.1 - 0.76 7.8 2.6 1.1 7.3 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Endonuclease_NS PF01223.23 KND88001.1 - 1.9e-66 224.1 0.0 2.3e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Zip PF02535.22 KND88002.1 - 2.7e-29 102.5 2.9 9.1e-29 100.7 2.9 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2236 PF09995.9 KND88003.1 - 0.0012 19.1 2.1 0.0021 18.3 2.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TMEM251 PF15190.6 KND88004.1 - 0.066 13.2 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 251 MFS_1 PF07690.16 KND88005.1 - 6.8e-25 87.7 31.5 7.6e-13 48.1 7.0 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 KND88005.1 - 4.1e-05 22.4 4.4 0.00026 19.8 0.0 3.4 2 2 2 4 4 4 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KND88005.1 - 0.00022 20.2 2.1 0.34 9.7 0.4 2.9 2 2 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KND88005.1 - 0.21 10.4 16.0 0.3 9.9 2.2 3.7 4 0 0 4 4 4 0 Sugar (and other) transporter LacY_symp PF01306.19 KND88005.1 - 1.1 8.0 11.3 0.094 11.5 1.9 2.6 3 0 0 3 3 3 0 LacY proton/sugar symporter Actin PF00022.19 KND88006.1 - 4.3e-30 104.7 0.0 1.4e-19 70.0 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KND88006.1 - 0.00054 19.3 0.8 0.56 9.3 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 KND88006.1 - 0.0029 18.0 0.0 0.022 15.2 0.0 2.3 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 KND88006.1 - 0.022 13.6 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein PHD PF00628.29 KND88007.1 - 1.7e-08 34.2 5.4 2.8e-08 33.5 5.4 1.3 1 0 0 1 1 1 1 PHD-finger CAP_N PF01213.19 KND88007.1 - 0.061 12.8 0.2 0.061 12.8 0.2 2.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal PHD_2 PF13831.6 KND88007.1 - 0.083 12.5 3.4 0.16 11.6 3.4 1.4 1 0 0 1 1 1 0 PHD-finger Iso_dh PF00180.20 KND88008.1 - 1.9e-80 270.6 0.0 2.6e-61 207.7 0.0 2.5 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF4451 PF14616.6 KND88009.1 - 4.1e-24 85.1 0.1 7.4e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Stm1_N PF09598.10 KND88011.1 - 0.0016 19.2 7.4 0.0016 19.2 7.4 3.5 2 1 0 2 2 2 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KND88011.1 - 0.0061 17.4 7.2 0.0061 17.4 7.2 2.6 3 2 0 3 3 3 1 Hyaluronan / mRNA binding family DUF3336 PF11815.8 KND88013.1 - 2.7e-49 166.4 5.2 4.6e-49 165.7 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND88013.1 - 2.4e-17 63.8 0.1 1.3e-16 61.4 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase DnaJ PF00226.31 KND88013.1 - 2.9e-15 56.1 1.5 7e-15 54.9 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KND88013.1 - 7.4e-08 31.9 0.0 0.00023 20.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DUF1772 PF08592.11 KND88013.1 - 0.031 14.6 0.0 7.2 6.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Myb_DNA-bind_2 PF08914.11 KND88014.1 - 0.045 13.9 0.0 8.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Rap1 Myb domain Mtd_N PF18454.1 KND88014.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain Pkinase PF00069.25 KND88015.1 - 2.9e-35 121.9 0.0 4.5e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88015.1 - 7.8e-21 74.5 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KND88015.1 - 9.2e-08 32.3 0.1 2.2e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Haspin_kinase PF12330.8 KND88015.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KND88015.1 - 0.15 10.8 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF5363 PF17320.2 KND88016.1 - 0.0069 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5363) YbaJ PF10757.9 KND88016.1 - 0.046 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ zf-C6H2 PF15801.5 KND88016.1 - 0.24 11.7 16.7 0.16 12.3 3.2 3.2 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Unstab_antitox PF09720.10 KND88016.1 - 0.3 11.1 3.3 0.3 11.2 0.3 2.6 2 0 0 2 2 2 0 Putative addiction module component zf-MYND PF01753.18 KND88016.1 - 2.1 8.5 27.2 0.17 12.0 4.3 3.8 4 0 0 4 4 4 0 MYND finger Stc1 PF12898.7 KND88016.1 - 8.6 7.0 16.9 0.35 11.4 2.0 3.4 3 0 0 3 3 3 0 Stc1 domain SF3b10 PF07189.11 KND88017.1 - 8.1e-30 102.8 0.0 9.8e-30 102.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KND88018.1 - 2.1e-65 220.4 0.2 3e-65 219.9 0.2 1.2 1 0 0 1 1 1 1 MAGE family SLS PF14611.6 KND88019.1 - 2.6e-38 132.1 2.8 4.9e-38 131.2 2.8 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF4443 PF14544.6 KND88019.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) Macoilin PF09726.9 KND88020.1 - 0.046 12.3 0.3 0.057 12.0 0.3 1.1 1 0 0 1 1 1 0 Macoilin family LPMO_10 PF03067.15 KND88021.1 - 0.075 13.7 0.0 0.17 12.5 0.0 1.5 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 KND88021.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 MFS_1 PF07690.16 KND88022.1 - 1e-15 57.5 57.8 1.8e-12 46.9 56.9 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2976 PF11190.8 KND88022.1 - 0.00079 19.2 3.3 0.024 14.5 0.8 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2976) TonB_N PF16031.5 KND88022.1 - 0.34 11.4 10.7 0.55 10.8 10.7 1.2 1 0 0 1 1 1 0 TonB polyproline region Tubulin PF00091.25 KND88023.1 - 1.7e-70 237.2 0.0 7.4e-70 235.2 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KND88023.1 - 4.1e-38 130.4 0.0 6.3e-38 129.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KND88023.1 - 3.5e-06 27.3 0.0 7.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KND88023.1 - 0.002 17.9 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KND88023.1 - 0.025 13.8 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DUF676 PF05057.14 KND88024.1 - 9.6e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND88024.1 - 6.2e-06 26.1 0.0 9.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND88024.1 - 1.3e-05 25.9 0.0 1.6e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 KND88024.1 - 0.00052 20.0 0.0 0.00079 19.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) LCAT PF02450.15 KND88024.1 - 0.0036 16.5 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 KND88024.1 - 0.012 15.5 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 KND88024.1 - 0.013 14.8 0.0 0.037 13.3 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KND88024.1 - 0.07 13.0 0.7 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Pyr_redox_3 PF13738.6 KND88025.1 - 5.5e-16 58.7 0.0 3.1e-13 49.7 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND88025.1 - 1e-15 57.8 0.0 7.1e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KND88025.1 - 7.2e-10 37.9 0.0 3.8e-09 35.5 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KND88025.1 - 4.6e-09 35.9 0.0 9e-06 25.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KND88025.1 - 6.3e-07 29.5 0.0 2.8e-06 27.5 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KND88025.1 - 1.4e-06 27.9 0.0 0.00018 20.9 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KND88025.1 - 1.1e-05 24.3 0.1 0.00061 18.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KND88025.1 - 2.1e-05 23.8 0.6 0.00029 20.0 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KND88025.1 - 0.00023 21.7 0.1 0.36 11.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND88025.1 - 0.00023 20.5 0.0 0.0011 18.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KND88025.1 - 0.00024 20.8 0.0 0.019 14.6 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 KND88025.1 - 0.00029 21.1 0.1 0.013 15.8 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 KND88025.1 - 0.00034 20.7 0.0 0.34 11.0 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KND88025.1 - 0.0012 18.2 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KND88025.1 - 0.0022 18.0 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KND88025.1 - 0.0024 17.0 0.1 0.0095 15.0 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.18 KND88025.1 - 0.0044 16.9 0.2 3.4 7.5 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 KND88025.1 - 0.015 14.4 0.5 1.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A IlvN PF07991.12 KND88025.1 - 0.021 14.4 0.2 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 KND88025.1 - 0.025 13.9 0.0 1.9 7.7 0.0 2.7 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KND88025.1 - 0.031 14.7 0.0 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.25 KND88025.1 - 0.069 12.6 0.0 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase EB_dh PF09459.10 KND88025.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase ApbA PF02558.16 KND88025.1 - 0.16 11.6 0.0 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FA_desaturase PF00487.24 KND88027.1 - 1.2e-21 77.7 23.0 3.7e-21 76.1 23.0 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KND88027.1 - 0.01 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Fungal_trans_2 PF11951.8 KND88028.1 - 9.7e-12 44.4 0.1 2.1e-11 43.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain K_oxygenase PF13434.6 KND88029.1 - 1.5e-10 40.8 0.0 3.2e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KND88029.1 - 1.7e-09 36.7 0.0 1.2e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND88029.1 - 2e-07 30.6 0.0 5.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND88029.1 - 4.7e-07 29.3 0.0 2.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND88029.1 - 3.3e-05 24.0 0.0 0.00022 21.4 0.0 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND88029.1 - 0.00011 21.5 0.0 0.00023 20.5 0.0 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KND88029.1 - 0.00053 19.7 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase ECH_1 PF00378.20 KND88030.1 - 4.6e-07 29.4 0.0 6.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MHYT PF03707.16 KND88032.1 - 2.4e-11 43.6 16.0 1.5e-06 28.3 0.7 4.8 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat Peptidase_U4 PF03419.13 KND88032.1 - 0.073 12.4 5.0 0.12 11.6 5.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF4131 PF13567.6 KND88032.1 - 7.9 6.1 11.0 13 5.4 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) P-mevalo_kinase PF04275.14 KND88035.1 - 1.5e-21 76.4 0.0 2.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 KND88035.1 - 2.8e-21 75.7 0.0 5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 KND88035.1 - 3.7e-13 49.4 3.7 9.6e-13 48.1 3.7 1.7 1 0 0 1 1 1 1 FAD binding domain UPRTase PF14681.6 KND88035.1 - 0.00017 21.1 0.1 0.00033 20.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 KND88035.1 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PRTase_2 PF15609.6 KND88035.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase p450 PF00067.22 KND88036.1 - 1.6e-57 195.3 0.0 2e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FTA2 PF13095.6 KND88040.1 - 0.00053 19.7 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Flavodoxin_NdrI PF07972.11 KND88040.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 NrdI Flavodoxin like MFS_1 PF07690.16 KND88041.1 - 9.2e-34 116.9 31.0 9.2e-34 116.9 31.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TUSC2 PF15000.6 KND88041.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Amidohydro_3 PF07969.11 KND88042.1 - 2.8e-14 53.5 7.4 3.1e-08 33.5 0.4 3.4 3 1 1 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 KND88042.1 - 3e-12 46.5 0.9 6.8e-10 38.8 0.1 3.6 3 1 0 3 3 3 1 Amidohydrolase family p450 PF00067.22 KND88043.1 - 5e-45 154.1 0.0 6.8e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KND88044.1 - 4.4e-61 206.5 0.0 5.5e-49 166.9 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KND88044.1 - 5e-21 75.1 0.0 1.9e-16 60.2 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase Sugar_tr PF00083.24 KND88045.1 - 1e-76 258.7 21.9 1.2e-76 258.4 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND88045.1 - 6.6e-20 71.3 52.2 6.7e-17 61.4 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KND88045.1 - 0.002 16.5 2.8 0.003 16.0 2.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) ABC2_membrane_2 PF12679.7 KND88045.1 - 0.018 14.3 4.9 0.035 13.4 4.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein GET2 PF08690.10 KND88045.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Aldedh PF00171.22 KND88046.1 - 8.4e-147 489.4 0.0 1e-146 489.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPR_14 PF13428.6 KND88046.1 - 0.0043 17.8 0.4 0.38 11.7 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND88046.1 - 0.0066 17.1 0.9 0.082 13.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Fungal_trans PF04082.18 KND88047.1 - 2e-22 79.5 0.0 2.9e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyclase PF04199.13 KND88048.1 - 6.8e-13 49.0 0.0 9.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 KND88048.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) adh_short_C2 PF13561.6 KND88049.1 - 2.1e-57 194.4 0.0 2.7e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND88049.1 - 2.5e-39 134.8 0.0 3.1e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND88049.1 - 1.5e-06 28.2 0.0 5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 KND88049.1 - 0.012 16.2 0.1 0.055 14.1 0.1 1.9 1 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Epimerase PF01370.21 KND88049.1 - 0.037 13.5 0.1 0.083 12.3 0.1 1.7 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KND88051.1 - 1.3e-39 136.1 34.4 2.9e-36 125.1 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND88051.1 - 1.3e-08 34.2 3.1 1.3e-08 34.2 3.1 2.3 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND88051.1 - 0.00072 18.1 0.4 0.0011 17.5 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KND88051.1 - 0.0032 16.4 0.0 0.015 14.2 0.0 2.3 1 1 0 1 1 1 1 MFS_1 like family GTP_EFTU PF00009.27 KND88052.1 - 1.1e-41 142.5 0.0 1.8e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KND88052.1 - 5.3e-41 139.4 0.2 1.8e-40 137.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KND88052.1 - 4.7e-15 55.7 0.8 1.3e-14 54.3 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KND88052.1 - 0.066 13.1 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 MFS_1 PF07690.16 KND88053.1 - 1.3e-39 136.2 66.5 5.7e-36 124.2 42.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND88053.1 - 6.2e-06 25.3 14.9 6.2e-06 25.3 14.9 2.8 2 2 0 2 2 2 2 Sugar (and other) transporter DUF3902 PF13042.6 KND88053.1 - 0.016 14.8 0.5 0.016 14.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) Phage_holin_3_6 PF07332.11 KND88053.1 - 0.024 14.7 2.1 0.024 14.7 2.1 4.4 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5090 PF17009.5 KND88053.1 - 0.37 10.7 6.4 0.44 10.5 2.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5090) Med12 PF09497.10 KND88054.1 - 2.1e-27 95.2 0.3 6.3e-27 93.6 0.3 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KND88054.1 - 2.6e-05 23.3 0.1 0.044 12.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain Serpin PF00079.20 KND88054.1 - 0.036 13.4 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Pyrid_oxidase_2 PF13883.6 KND88055.1 - 1.4e-39 135.8 0.0 2.4e-39 135.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fic PF02661.18 KND88059.1 - 6.7e-08 33.3 0.1 1.8e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 Fic/DOC family IBR PF01485.21 KND88061.1 - 1.3e-09 38.1 37.4 9e-05 22.6 9.0 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KND88061.1 - 7.3e-05 23.0 5.7 7.3e-05 23.0 5.7 3.8 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KND88061.1 - 0.00033 20.5 6.6 0.00033 20.5 6.6 3.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND88061.1 - 0.00044 20.2 6.0 0.00044 20.2 6.0 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND88061.1 - 0.0005 20.0 6.5 0.0005 20.0 6.5 3.9 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KND88061.1 - 0.0028 17.4 4.5 0.0028 17.4 4.5 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PKK PF12474.8 KND88061.1 - 0.0074 16.4 6.8 0.0074 16.4 6.8 2.6 2 1 0 2 2 2 1 Polo kinase kinase zf-RING_11 PF17123.5 KND88061.1 - 0.028 14.2 0.8 0.028 14.2 0.8 3.3 3 1 1 4 4 4 0 RING-like zinc finger RhoGAP PF00620.27 KND88063.1 - 1.4e-42 145.0 0.0 3.3e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 KND88063.1 - 1.4e-12 47.7 1.4 1.6e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KND88063.1 - 0.16 11.3 8.7 0.056 12.8 6.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 KND88063.1 - 0.31 11.4 11.8 0.48 10.8 9.0 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 KND88063.1 - 6.8 5.1 6.5 11 4.4 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Adaptin_N PF01602.20 KND88065.1 - 1.6e-112 376.8 0.5 2.3e-112 376.2 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KND88065.1 - 3.4e-57 192.8 4.2 6.9e-57 191.8 4.2 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KND88065.1 - 2.6e-36 124.3 0.1 7.4e-36 122.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KND88065.1 - 5.5e-16 58.7 3.5 1.1e-10 41.8 0.1 5.3 3 1 3 6 6 6 1 HEAT repeats Cnd1 PF12717.7 KND88065.1 - 1.7e-06 28.2 11.3 0.051 13.6 0.1 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KND88065.1 - 0.013 16.1 0.0 13 6.9 0.0 4.2 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat CLASP_N PF12348.8 KND88065.1 - 0.017 14.7 3.2 0.049 13.2 0.1 2.9 3 0 0 3 3 3 0 CLASP N terminal HEAT PF02985.22 KND88065.1 - 0.041 14.1 7.3 1.6 9.2 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat DUF5010 PF16402.5 KND88065.1 - 0.082 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) RTP1_C1 PF10363.9 KND88065.1 - 0.11 12.7 0.4 6 7.1 0.0 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptin_C PF02296.16 KND88065.1 - 0.14 12.3 0.0 0.8 9.9 0.0 2.3 2 1 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain ATP12 PF07542.11 KND88066.1 - 3.8e-41 140.2 0.1 7e-41 139.3 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein RRM_1 PF00076.22 KND88068.1 - 1.7e-15 56.6 0.0 1e-12 47.7 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KND88068.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 KND88068.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif adh_short PF00106.25 KND88069.1 - 1e-29 103.4 0.0 1.3e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND88069.1 - 7.8e-23 81.2 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND88069.1 - 2.3e-10 40.7 0.1 7e-09 35.8 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 KND88069.1 - 0.1 13.2 0.0 7.2 7.3 0.0 3.1 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain Ras PF00071.22 KND88070.1 - 6e-51 172.3 0.0 7.2e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND88070.1 - 6.9e-18 65.0 0.0 9.5e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND88070.1 - 4e-09 36.1 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND88070.1 - 3.5e-05 23.4 0.1 0.00035 20.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KND88070.1 - 0.00011 22.1 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KND88070.1 - 0.001 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KND88070.1 - 0.05 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KND88070.1 - 0.059 13.8 0.1 0.07 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Scytalone_dh PF02982.14 KND88070.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Scytalone dehydratase AAA_22 PF13401.6 KND88070.1 - 0.15 12.3 0.1 1.6 9.0 0.0 2.3 2 1 0 3 3 3 0 AAA domain POP1 PF06978.11 KND88072.1 - 1.7e-64 217.6 12.5 1.7e-64 217.6 12.5 1.6 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KND88072.1 - 2.1e-29 101.7 0.1 6.3e-29 100.2 0.1 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain EAF PF09816.9 KND88073.1 - 7.4e-14 52.0 0.0 2.4e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Ric8 PF10165.9 KND88074.1 - 4.5e-71 240.3 0.0 4.6e-58 197.4 0.0 2.0 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn CDC14 PF08045.11 KND88074.1 - 0.14 11.2 0.1 0.27 10.3 0.1 1.4 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Mg_trans_NIPA PF05653.14 KND88075.1 - 6.4e-92 307.8 22.9 8.3e-92 307.4 22.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KND88075.1 - 2e-05 24.8 31.5 4.3e-05 23.7 7.4 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF805 PF05656.14 KND88075.1 - 0.25 11.7 10.9 2.4 8.6 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Auxin_repressed PF05564.12 KND88075.1 - 0.72 10.6 3.1 0.45 11.2 0.8 1.8 2 0 0 2 2 2 0 Dormancy/auxin associated protein Deltameth_res PF16020.5 KND88075.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Deltamethrin resistance adh_short PF00106.25 KND88076.1 - 1.8e-15 57.0 0.2 8.5e-15 54.7 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND88076.1 - 7.4e-07 29.0 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND88076.1 - 4.5e-06 26.7 0.2 7.3e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 KR domain ANAPC_CDC26 PF10471.9 KND88076.1 - 0.11 13.4 0.0 0.22 12.4 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Pkinase PF00069.25 KND88077.1 - 7.8e-36 123.8 0.0 3e-35 121.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88077.1 - 9.3e-12 44.8 0.0 3e-10 39.8 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KND88080.1 - 2.8e-19 69.5 0.0 8.4e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88080.1 - 9.9e-08 31.6 0.1 2.8e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 KND88081.1 - 3.8e-27 95.3 14.5 1.3e-26 93.6 14.5 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND88081.1 - 0.031 14.9 2.0 0.44 11.2 0.3 3.2 2 1 0 2 2 2 0 Peptidase inhibitor I9 Sugar_tr PF00083.24 KND88082.1 - 2.1e-81 274.1 26.8 2.4e-81 273.9 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND88082.1 - 3.3e-18 65.7 54.9 1.6e-16 60.2 30.8 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 KND88083.1 - 2.5e-23 82.8 0.0 6.7e-17 61.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND88083.1 - 6.5e-07 28.9 0.0 4.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase BNR_2 PF13088.6 KND88089.1 - 3.3e-18 66.0 0.2 9.5e-13 48.1 0.2 3.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 KND88089.1 - 0.00012 21.5 28.6 0.66 10.2 1.4 7.0 6 0 0 6 6 6 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KND88089.1 - 0.0062 15.4 0.8 0.77 8.5 0.1 2.6 1 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 KND88089.1 - 0.0091 15.3 0.6 2.6 7.3 0.1 3.0 1 1 1 2 2 2 1 BNR repeat-like domain PSII_BNR PF14870.6 KND88089.1 - 0.016 14.5 3.6 5.3 6.2 0.3 4.0 4 1 0 4 4 4 0 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 KND88089.1 - 0.017 15.1 1.3 2.5 8.1 0.0 3.5 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain BNR_4 PF15892.5 KND88089.1 - 0.046 13.1 0.3 0.42 9.9 0.3 2.3 1 1 1 2 2 2 0 BNR repeat-containing family member Glyco_hydro_71 PF03659.14 KND88090.1 - 5.4e-93 311.8 3.0 6.9e-93 311.4 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 KND88093.1 - 2.9e-06 26.9 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND88093.1 - 2.9e-05 23.5 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YacG PF03884.14 KND88093.1 - 0.043 13.5 0.1 0.093 12.5 0.1 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG APH PF01636.23 KND88093.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M20 PF01546.28 KND88095.1 - 6.4e-31 107.7 0.1 9.6e-31 107.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND88095.1 - 5.2e-10 39.2 0.0 1.6e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain ABC_tran PF00005.27 KND88096.1 - 1e-43 149.2 0.0 3.2e-25 89.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND88096.1 - 5.7e-30 104.9 17.9 9e-17 61.6 4.8 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KND88096.1 - 5.7e-13 48.8 0.4 0.0029 17.1 0.0 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND88096.1 - 1.1e-07 31.9 0.9 0.31 10.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KND88096.1 - 2.4e-07 30.5 0.5 0.025 14.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 KND88096.1 - 4.8e-07 29.1 0.2 0.00054 19.1 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 KND88096.1 - 7.9e-07 29.4 1.0 0.015 15.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KND88096.1 - 8.3e-07 28.7 0.3 0.051 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KND88096.1 - 1.6e-06 28.6 1.5 0.066 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KND88096.1 - 5.1e-06 27.1 0.1 0.0013 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KND88096.1 - 0.00019 21.5 1.0 0.036 14.1 0.3 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND88096.1 - 0.00021 21.2 0.4 0.2 11.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 KND88096.1 - 0.00048 19.4 0.0 0.85 8.8 0.1 2.7 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KND88096.1 - 0.00052 20.0 0.3 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 KND88096.1 - 0.0006 20.2 0.6 1.8 9.0 0.1 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KND88096.1 - 0.00066 19.0 1.1 0.36 10.0 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 KND88096.1 - 0.00069 19.4 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein cobW PF02492.19 KND88096.1 - 0.0011 18.5 4.7 0.02 14.5 1.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KND88096.1 - 0.0014 18.8 3.6 0.015 15.4 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Viral_helicase1 PF01443.18 KND88096.1 - 0.0017 18.1 0.1 0.32 10.7 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Pox_A32 PF04665.12 KND88096.1 - 0.0018 17.8 0.5 1.7 8.0 0.1 2.2 2 0 0 2 2 2 2 Poxvirus A32 protein CbiA PF01656.23 KND88096.1 - 0.0025 17.9 0.0 6.2 6.9 0.0 3.5 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KND88096.1 - 0.0025 17.6 0.3 1.9 8.2 0.1 3.0 3 1 0 3 3 2 1 DEAD/DEAH box helicase Dynamin_N PF00350.23 KND88096.1 - 0.0032 17.5 1.5 1.7 8.7 0.5 2.3 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 KND88096.1 - 0.0034 17.1 0.2 4.4 7.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 KND88096.1 - 0.0046 17.2 0.5 3.3 8.0 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 KND88096.1 - 0.0058 17.2 0.5 4.9 7.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KND88096.1 - 0.0081 16.3 10.6 0.099 12.8 1.2 3.5 3 1 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.18 KND88096.1 - 0.0082 15.5 0.2 1.8 7.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KND88096.1 - 0.011 15.5 7.9 0.7 9.6 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KND88096.1 - 0.012 15.1 0.5 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KND88096.1 - 0.018 14.3 0.6 1.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 KND88096.1 - 0.021 13.8 0.9 4.6 6.0 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 KND88096.1 - 0.025 14.1 0.1 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 KND88096.1 - 0.028 14.3 4.0 3.5 7.5 0.6 2.5 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 KND88096.1 - 0.042 14.2 0.2 20 5.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.6 KND88096.1 - 0.068 12.9 0.1 1.3 8.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KND88096.1 - 0.069 13.2 1.2 3.9 7.5 0.1 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KND88096.1 - 0.083 12.8 0.0 0.95 9.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KND88096.1 - 0.11 12.5 0.1 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KND88096.1 - 0.11 12.7 0.1 25 5.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase PF06745.13 KND88096.1 - 0.17 11.2 0.2 16 4.7 0.1 2.5 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 KND88096.1 - 0.19 11.7 0.1 25 4.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KND88096.1 - 0.2 11.9 2.6 5 7.4 0.4 2.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 KND88096.1 - 0.26 10.8 0.4 5.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KND88096.1 - 0.31 10.8 1.7 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF1761 PF08570.10 KND88096.1 - 5.9 7.2 11.5 0.11 12.7 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Acatn PF13000.7 KND88097.1 - 9.8e-162 539.3 17.3 7.2e-82 275.6 8.3 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DFP PF04127.15 KND88098.1 - 1.7e-12 47.6 0.0 1.4e-05 25.1 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein CENP-O PF09496.10 KND88100.1 - 4.8e-67 226.1 0.0 7.7e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Pkinase PF00069.25 KND88101.1 - 6.6e-60 202.7 0.0 6.3e-59 199.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88101.1 - 2.2e-28 99.3 0.2 9.3e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KND88101.1 - 0.0052 17.5 4.1 0.0058 17.3 1.2 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KND88101.1 - 0.0065 15.8 0.5 0.027 13.8 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 KND88101.1 - 0.0073 16.3 0.6 0.094 12.6 0.2 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND88101.1 - 0.036 13.0 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KND88101.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Na_H_Exchanger PF00999.21 KND88102.1 - 1.9e-26 92.8 36.0 1.7e-24 86.3 29.7 3.0 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family Wbp11 PF09429.10 KND88102.1 - 6.7e-23 80.9 9.9 1.3e-22 79.9 9.9 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 Iso_dh PF00180.20 KND88103.1 - 8.8e-105 350.7 0.0 1e-104 350.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Yae1_N PF09811.9 KND88104.1 - 1.2e-13 50.5 0.7 1.9e-13 49.8 0.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal APG12 PF04110.13 KND88105.1 - 1.9e-06 28.2 0.0 3.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PolyA_pol_RNAbd PF12627.7 KND88105.1 - 0.14 12.0 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A DUF3043 PF11241.8 KND88105.1 - 0.21 11.6 0.8 0.34 10.9 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Lyase_aromatic PF00221.19 KND88106.1 - 4.7e-130 434.4 5.6 8.8e-82 275.2 2.1 2.1 1 1 1 2 2 2 2 Aromatic amino acid lyase DUF572 PF04502.13 KND88107.1 - 2.3e-58 198.4 0.0 2.7e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pantoate_transf PF02548.15 KND88109.1 - 4.1e-102 341.0 0.1 4.9e-102 340.7 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KND88109.1 - 2.6e-09 36.9 0.4 4e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KND88109.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) NmrA PF05368.13 KND88110.1 - 6.5e-27 94.6 0.0 8.8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND88110.1 - 3.6e-20 72.6 0.0 5.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND88110.1 - 0.0004 19.9 0.1 0.00088 18.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KND88110.1 - 0.00077 19.6 0.1 0.002 18.3 0.1 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 KND88110.1 - 0.0036 16.3 0.0 0.006 15.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KND88110.1 - 0.015 15.7 0.1 0.046 14.2 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KND88110.1 - 0.023 14.6 0.2 0.041 13.8 0.2 1.4 1 1 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 KND88110.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 KND88110.1 - 0.063 12.4 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Fungal_trans PF04082.18 KND88111.1 - 1.9e-10 40.2 3.7 3e-10 39.6 3.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88111.1 - 4.6e-07 29.9 8.4 1.1e-06 28.7 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KND88111.1 - 2.6e-05 24.4 16.0 0.0017 18.7 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND88111.1 - 0.005 17.6 21.0 0.074 13.9 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger DUF3318 PF11780.8 KND88111.1 - 0.037 14.0 0.9 0.36 10.8 0.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3318) Neurochondrin PF05536.11 KND88111.1 - 0.058 11.8 0.0 0.082 11.3 0.0 1.1 1 0 0 1 1 1 0 Neurochondrin MFS_1 PF07690.16 KND88112.1 - 1.1e-30 106.7 25.5 1.4e-15 57.1 11.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND88112.1 - 4.8e-07 28.7 28.8 0.00079 18.1 18.7 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KND88112.1 - 0.0014 17.6 15.9 0.021 13.7 8.7 2.2 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KND88112.1 - 0.06 12.2 21.5 0.027 13.4 9.3 3.4 2 2 1 3 3 3 0 Sugar (and other) transporter MFS_3 PF05977.13 KND88112.1 - 2.9 6.2 20.2 0.13 10.6 8.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Synaptobrevin PF00957.21 KND88113.1 - 0.084 12.7 0.3 0.2 11.5 0.1 1.7 1 1 1 2 2 2 0 Synaptobrevin ArfGap PF01412.18 KND88114.1 - 3e-40 136.9 1.0 4.5e-40 136.4 1.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Thiolase_N PF00108.23 KND88116.1 - 1.4e-72 244.2 5.4 1.8e-72 243.8 5.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND88116.1 - 1.5e-40 137.7 0.3 5.1e-40 135.9 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND88116.1 - 0.017 14.7 1.4 0.074 12.6 0.5 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 KND88116.1 - 0.058 13.6 0.0 0.22 11.7 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cadherin_tail PF15974.5 KND88116.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region OCD_Mu_crystall PF02423.15 KND88117.1 - 6.6e-11 41.7 0.2 3.9e-09 35.9 0.0 2.4 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KND88117.1 - 0.025 14.7 0.2 9.1 6.3 0.0 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase QWRF PF04484.12 KND88117.1 - 0.59 9.8 2.3 1.1 8.9 2.3 1.4 1 0 0 1 1 1 0 QWRF family Cg6151-P PF10233.9 KND88118.1 - 4.4e-40 136.5 13.9 5.2e-40 136.3 13.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Fer4_20 PF14691.6 KND88118.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF2518 PF10726.9 KND88118.1 - 0.27 10.9 8.7 2.3 7.9 2.1 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) CitMHS PF03600.16 KND88118.1 - 0.42 9.8 8.9 0.49 9.5 8.9 1.1 1 0 0 1 1 1 0 Citrate transporter DUF4149 PF13664.6 KND88118.1 - 0.51 10.7 8.6 0.16 12.3 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Cytochrom_B558a PF05038.13 KND88118.1 - 1.6 8.3 5.3 3.4 7.2 5.3 1.6 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF308 PF03729.13 KND88118.1 - 2.7 8.4 18.2 0.67 10.3 1.5 2.9 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Aim21 PF11489.8 KND88119.1 - 8.5e-174 580.4 81.9 8.5e-174 580.4 81.9 2.0 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 21 Glyco_hydro_16 PF00722.21 KND88120.1 - 3e-43 147.4 1.8 3e-43 147.4 1.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Peptidase_M4_C PF02868.15 KND88121.1 - 4e-48 163.5 0.0 6.1e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KND88121.1 - 5.8e-23 82.0 0.1 1e-22 81.2 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 KND88121.1 - 1e-14 54.0 0.0 1.1e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 Protealysin propeptide DUF1373 PF07117.11 KND88121.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Glyco_hydro_18 PF00704.28 KND88122.1 - 1e-47 163.4 0.0 1.7e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KND88122.1 - 1.2e-11 44.5 0.0 7.5e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KND88122.1 - 0.0053 17.2 3.3 0.0053 17.2 3.3 4.5 4 1 0 4 4 4 1 Chitin recognition protein Prenyltrans PF00432.21 KND88124.1 - 2.2e-24 84.9 27.7 2.2e-06 27.3 0.4 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KND88124.1 - 0.0011 18.1 0.0 0.0072 15.5 0.0 2.1 3 0 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain Zn_clus PF00172.18 KND88125.1 - 0.0038 17.3 7.7 0.0079 16.3 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KND88125.1 - 6.1 6.7 10.7 11 5.8 10.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_92 PF07971.12 KND88126.1 - 6.4e-107 358.3 0.0 7.3e-107 358.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 SIR2 PF02146.17 KND88127.1 - 5.8e-30 104.5 0.0 2.3e-29 102.5 0.0 1.8 1 1 0 1 1 1 1 Sir2 family BRAP2 PF07576.12 KND88128.1 - 1.2e-30 105.6 0.0 2e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KND88128.1 - 1.6e-18 66.8 7.6 3.9e-18 65.5 7.6 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 KND88128.1 - 1.2e-08 35.1 9.3 1.2e-08 35.1 9.3 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KND88128.1 - 2.2e-07 30.5 5.1 7.3e-07 28.8 5.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND88128.1 - 2.8e-06 27.0 9.6 7.5e-06 25.7 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND88128.1 - 2.1e-05 24.3 8.3 5.6e-05 22.9 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND88128.1 - 2.6e-05 24.1 6.1 0.00013 21.9 6.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND88128.1 - 7.6e-05 22.6 7.4 7.6e-05 22.6 7.4 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KND88128.1 - 0.00022 21.0 6.2 0.00022 21.0 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND88128.1 - 0.00071 19.8 6.8 0.0021 18.3 6.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain MCC-bdg_PDZ PF10506.9 KND88128.1 - 0.004 17.1 0.6 0.011 15.7 0.6 1.8 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Prok-RING_4 PF14447.6 KND88128.1 - 0.015 15.1 10.8 0.015 15.1 10.8 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 KND88128.1 - 0.023 14.6 3.8 0.065 13.1 3.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KND88128.1 - 0.084 12.9 5.3 0.24 11.5 5.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 KND88128.1 - 0.12 12.9 16.7 1.1 9.7 3.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB IKBKB_SDD PF18397.1 KND88128.1 - 0.13 11.6 3.5 0.19 11.0 3.5 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain bZIP_1 PF00170.21 KND88128.1 - 0.31 11.2 7.9 0.13 12.4 4.5 2.2 2 0 0 2 2 2 0 bZIP transcription factor FlgN PF05130.12 KND88128.1 - 0.41 11.1 9.4 0.72 10.4 9.4 1.3 1 0 0 1 1 1 0 FlgN protein JIP_LZII PF16471.5 KND88128.1 - 0.69 10.1 8.1 0.1 12.8 2.9 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Rootletin PF15035.6 KND88128.1 - 1 9.4 11.3 1.9 8.5 11.3 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KND88128.1 - 2.3 8.2 19.4 5 7.2 7.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 KND88128.1 - 3.5 7.4 15.9 5.7 6.7 15.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Exonuc_VII_L PF02601.15 KND88128.1 - 4.2 6.9 7.6 6.5 6.2 7.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KND88128.1 - 5.3 6.3 11.5 0.46 9.8 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) AKNA PF12443.8 KND88128.1 - 5.9 7.6 6.3 0.7 10.6 1.3 2.1 2 0 0 2 2 1 0 AT-hook-containing transcription factor Cpn60_TCP1 PF00118.24 KND88130.1 - 1.1e-155 519.0 5.6 1.4e-155 518.7 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 KND88130.1 - 0.33 11.1 2.5 13 6.0 0.1 3.1 3 0 0 3 3 3 0 Enolase, N-terminal domain RTA1 PF04479.13 KND88131.1 - 1.4e-17 64.0 0.7 1.5e-17 63.9 0.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2461 PF09365.10 KND88132.1 - 5.4e-77 258.5 0.1 6.6e-77 258.2 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) HSP70 PF00012.20 KND88133.1 - 1.6e-262 872.1 15.6 1.8e-262 871.9 15.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND88133.1 - 4.1e-18 65.3 2.6 7.2e-17 61.2 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KND88133.1 - 0.00058 20.2 2.7 1.8 9.0 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 KND88133.1 - 0.0012 18.0 0.2 0.14 11.1 0.1 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 KND88133.1 - 0.017 14.4 2.3 0.091 12.0 0.1 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF1464 PF07318.12 KND88133.1 - 0.021 14.0 0.6 0.99 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) HOIP-UBA PF16678.5 KND88133.1 - 0.042 13.9 0.5 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 HOIP UBA domain pair GTP_EFTU PF00009.27 KND88134.1 - 2.2e-47 161.2 0.0 4e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KND88134.1 - 4.5e-25 87.7 2.1 1.1e-24 86.6 2.1 1.6 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KND88134.1 - 6.2e-09 36.2 0.0 2.2e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KND88134.1 - 2e-07 31.3 0.1 6.5e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND88134.1 - 2.2e-07 31.0 0.0 8.3e-06 25.9 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KND88134.1 - 0.0093 16.2 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND88134.1 - 0.11 11.9 0.0 4.6 6.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit KCH PF16944.5 KND88135.1 - 2.5e-100 335.4 3.5 3e-100 335.2 3.5 1.0 1 0 0 1 1 1 1 Fungal potassium channel Putative_PNPOx PF01243.20 KND88136.1 - 0.00013 22.1 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 KND88136.1 - 0.073 13.7 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain CTP_transf_like PF01467.26 KND88137.1 - 1.7e-27 96.4 0.0 3.3e-27 95.4 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like Exo_endo_phos PF03372.23 KND88139.1 - 5.5e-05 22.8 0.1 0.00011 21.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fibritin_C PF07921.12 KND88139.1 - 0.062 13.4 0.1 21 5.3 0.0 2.9 2 0 0 2 2 2 0 Fibritin C-terminal region FUSC_2 PF13515.6 KND88140.1 - 2.1e-09 37.6 37.8 9.7e-09 35.4 9.9 3.4 2 1 1 3 3 3 3 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 KND88140.1 - 2.9e-08 33.2 13.2 4e-05 22.8 1.3 3.2 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal ESSS PF10183.9 KND88141.1 - 1.8e-08 34.5 0.0 2.5e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DASH_Duo1 PF08651.10 KND88142.1 - 1.2e-27 95.5 0.0 1.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 API5 PF05918.11 KND88142.1 - 0.13 11.1 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RNase_H2-Ydr279 PF09468.10 KND88143.1 - 1.8e-46 158.2 0.7 3.7e-46 157.2 0.0 1.9 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KND88143.1 - 1.6e-25 89.1 0.0 4.4e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain SurE PF01975.17 KND88144.1 - 8.9e-53 179.0 0.0 1.5e-52 178.2 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 KND88144.1 - 5e-52 176.9 0.0 7.5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KND88144.1 - 0.00039 19.8 0.0 0.00089 18.6 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp Hemopexin PF00045.19 KND88145.1 - 0.069 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Hemopexin SIR2 PF02146.17 KND88146.1 - 8.8e-59 198.4 0.0 1.3e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KND88146.1 - 0.0041 16.9 0.2 0.094 12.5 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 KND88146.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) TackOD1 PF18551.1 KND88146.1 - 0.19 11.4 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Cation_ATPase_C PF00689.21 KND88147.1 - 1.2e-40 139.1 4.6 1.2e-40 139.1 4.6 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KND88147.1 - 1.9e-32 112.3 0.4 1.9e-32 112.3 0.4 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KND88147.1 - 3.4e-22 78.3 0.0 6.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND88147.1 - 3.6e-20 73.2 0.6 3.2e-19 70.0 0.3 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND88147.1 - 9.9e-07 28.4 0.0 9.4e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND88147.1 - 1.3e-05 25.1 0.4 2.9e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND88147.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KND88147.1 - 0.63 8.8 4.9 1.7 7.4 4.9 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Aminotran_4 PF01063.19 KND88148.1 - 1e-34 120.3 0.0 1.4e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KND88149.1 - 4.4e-15 55.8 0.0 2e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88149.1 - 2.4e-07 30.3 0.0 1.1e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KND88149.1 - 0.0015 18.3 0.2 0.0081 15.8 0.1 2.1 1 1 1 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 CN_hydrolase PF00795.22 KND88150.1 - 2.7e-28 99.0 0.1 3.3e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase p450 PF00067.22 KND88151.1 - 8.4e-31 107.2 0.0 1.6e-30 106.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.22 KND88152.1 - 8.9e-31 107.1 0.0 1.7e-30 106.2 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 HLH PF00010.26 KND88153.1 - 1.2e-14 54.0 0.0 2.3e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M24 PF00557.24 KND88154.1 - 2.5e-50 171.1 0.0 4e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KND88154.1 - 5.4e-35 119.8 0.1 8.5e-35 119.2 0.1 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 KND88155.1 - 2.9e-43 147.1 0.7 9.5e-43 145.4 0.0 2.2 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 KND88155.1 - 1.3e-21 76.4 0.3 2.3e-21 75.6 0.3 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 KND88155.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain Aha1_N PF09229.11 KND88157.1 - 5.9e-44 149.6 0.2 8.9e-44 149.0 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KND88157.1 - 1.3e-19 70.7 0.3 2.8e-19 69.6 0.3 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SH3BGR PF04908.15 KND88157.1 - 0.0037 17.4 0.5 3.7 7.8 0.1 3.3 2 1 1 3 3 3 2 SH3-binding, glutamic acid-rich protein DHHC PF01529.20 KND88158.1 - 7.5e-31 107.0 2.7 7.5e-31 107.0 2.7 2.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase SARAF PF06682.12 KND88158.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Rap1_C PF11626.8 KND88159.1 - 1.9e-25 88.7 0.0 7.5e-24 83.6 0.0 2.8 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KND88159.1 - 7.1e-17 61.3 2.3 9.7e-17 60.9 0.3 2.3 3 0 0 3 3 3 1 Rap1 Myb domain ARID PF01388.21 KND88159.1 - 2.3e-07 31.4 0.0 5.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BRCT_2 PF16589.5 KND88159.1 - 1.1e-06 29.0 0.0 4.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KND88159.1 - 0.0006 20.4 0.0 0.0034 18.0 0.0 2.2 2 0 0 2 2 2 1 Rap1, DNA-binding AGA2 PF17366.2 KND88159.1 - 0.091 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 Histone_HNS PF00816.21 KND88159.1 - 1.1 10.1 8.6 1.2 10.0 0.5 3.5 3 0 0 3 3 3 0 H-NS histone family Tubulin PF00091.25 KND88160.1 - 4.3e-68 229.4 0.0 1.2e-67 227.9 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KND88160.1 - 1.3e-42 144.9 0.1 2e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L6 PF00347.23 KND88160.1 - 4.5e-12 46.5 0.0 4.9e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L6 Misat_Tub_SegII PF10644.9 KND88160.1 - 4e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KND88160.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 KND88160.1 - 0.011 14.9 0.0 0.047 12.9 0.0 1.8 2 0 0 2 2 2 0 Tubulin like FtsJ PF01728.19 KND88162.1 - 1.1e-62 211.3 0.0 1.4e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DCB PF16213.5 KND88163.1 - 2.7e-47 160.7 8.7 1.4e-46 158.4 5.5 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KND88163.1 - 7.6e-42 142.9 0.1 7.6e-42 142.9 0.1 4.4 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KND88163.1 - 1.4e-28 99.6 6.0 2.3e-20 72.4 0.7 3.4 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 KND88163.1 - 4.6e-06 26.4 0.1 0.00032 20.5 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Pribosyltran_N PF13793.6 KND88164.1 - 5.7e-43 145.6 0.3 1.3e-42 144.4 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KND88164.1 - 5.6e-38 130.8 2.6 8.7e-29 100.9 1.0 3.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KND88164.1 - 1.5e-14 53.8 0.4 2.9e-14 52.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KND88164.1 - 0.0028 17.1 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 KND88164.1 - 0.16 11.9 1.9 0.27 11.2 1.1 1.7 1 1 0 1 1 1 0 Chlorosome envelope protein C Flavoprotein PF02441.19 KND88165.1 - 5.1e-19 68.6 0.0 8.4e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein UQ_con PF00179.26 KND88167.1 - 5e-16 58.6 0.0 6.1e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KND88167.1 - 0.042 14.1 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain Band_7 PF01145.25 KND88168.1 - 3.7e-30 105.2 0.4 7.4e-30 104.3 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KND88168.1 - 3.4e-23 81.4 0.1 1e-22 79.9 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 KND88168.1 - 0.002 17.5 0.2 0.004 16.5 0.2 1.6 1 0 0 1 1 1 1 Poxvirus A11 Protein KH_1 PF00013.29 KND88169.1 - 8.5e-90 294.6 28.5 2.9e-14 52.6 0.1 13.4 14 1 0 14 14 14 9 KH domain SLS PF14611.6 KND88169.1 - 2.5e-12 47.1 4.5 0.0083 16.0 0.0 7.5 4 2 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KND88169.1 - 9.1e-11 41.4 22.6 0.032 14.0 0.3 7.7 6 1 1 7 7 7 4 KH domain BON PF04972.17 KND88169.1 - 0.0028 17.9 3.8 1.7 9.0 0.1 4.4 3 0 0 3 3 3 1 BON domain KH_4 PF13083.6 KND88169.1 - 0.0049 16.7 8.1 1.3 9.0 0.0 5.3 6 0 0 6 6 6 2 KH domain MPDZ_u10 PF16667.5 KND88169.1 - 0.12 13.3 2.9 0.53 11.2 2.4 2.5 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein DUF5300 PF17224.3 KND88169.1 - 0.15 12.3 4.1 22 5.4 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) YqgF PF14639.6 KND88169.1 - 0.2 11.4 1.3 0.92 9.3 0.1 2.8 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 CDV3 PF15359.6 KND88169.1 - 0.72 10.3 4.1 1.3 9.5 0.6 2.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Secretin_N PF03958.17 KND88169.1 - 2.3 8.7 5.8 49 4.4 0.1 4.4 4 1 1 5 5 5 0 Bacterial type II/III secretion system short domain Pkinase PF00069.25 KND88170.1 - 2e-71 240.5 0.0 2.7e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88170.1 - 2.1e-46 158.3 0.0 3.5e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KND88170.1 - 3.8e-19 68.8 0.0 2e-18 66.5 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KND88170.1 - 8.2e-08 31.9 0.4 2.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KND88170.1 - 1.5e-07 30.6 0.0 3.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KND88170.1 - 0.0055 15.7 0.1 0.0098 14.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND88170.1 - 0.04 13.3 0.1 0.36 10.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88170.1 - 0.057 13.3 1.6 0.15 11.9 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 KND88171.1 - 2.4e-61 207.3 1.4 3.2e-61 206.9 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND88171.1 - 1.4e-50 171.5 0.8 2e-50 171.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND88171.1 - 1.2e-12 48.1 0.4 1.7e-12 47.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND88171.1 - 1.8e-06 27.6 0.2 4.3e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND88171.1 - 0.0009 18.7 0.2 0.0022 17.4 0.2 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KND88171.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PA PF02225.22 KND88171.1 - 0.023 14.7 0.3 0.062 13.3 0.1 1.9 2 0 0 2 2 2 0 PA domain Methyltransf_25 PF13649.6 KND88171.1 - 0.085 13.6 0.1 0.19 12.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Metallophos_2 PF12850.7 KND88172.1 - 2.6e-07 31.0 0.1 4.7e-06 26.9 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KND88172.1 - 8.9e-05 23.1 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PRP21_like_P PF12230.8 KND88172.1 - 0.02 14.7 0.4 0.032 14.1 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Transp_inhibit PF18791.1 KND88172.1 - 0.073 12.6 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain ARID PF01388.21 KND88173.1 - 8.8e-16 58.4 0.0 2.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Arm PF00514.23 KND88173.1 - 0.02 14.9 0.4 4.3 7.5 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Hap4_Hap_bind PF10297.9 KND88173.1 - 0.21 11.7 0.7 0.59 10.3 0.7 1.8 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Dna2 PF08696.11 KND88175.1 - 8e-66 221.7 0.0 1.8e-65 220.6 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KND88175.1 - 9.2e-53 178.8 0.0 1.6e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND88175.1 - 2.8e-32 112.5 0.1 1.6e-15 57.7 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KND88175.1 - 2.3e-16 60.1 0.0 5.5e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND88175.1 - 5.1e-13 49.6 0.0 2.6e-12 47.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KND88175.1 - 1.2e-08 35.2 0.1 2.6e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KND88175.1 - 8e-06 25.8 0.8 0.27 10.9 0.1 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KND88175.1 - 2.8e-05 24.1 0.0 6.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KND88175.1 - 0.0015 17.8 0.0 0.067 12.4 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase SRP54 PF00448.22 KND88175.1 - 0.0017 18.0 0.2 0.0035 17.0 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KND88175.1 - 0.003 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 KND88175.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KND88175.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 KND88175.1 - 0.017 15.2 0.3 0.039 14.0 0.3 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 KND88175.1 - 0.018 15.0 0.2 0.076 12.9 0.3 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 KND88175.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 KND88175.1 - 0.04 14.0 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 KND88175.1 - 0.048 12.7 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 KND88175.1 - 0.088 11.8 0.0 0.24 10.4 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 KND88175.1 - 0.098 12.6 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 KND88175.1 - 0.1 12.2 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 KND88175.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KND88175.1 - 0.15 12.1 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Aminopep PF10023.9 KND88176.1 - 0.044 13.2 1.6 1.5 8.1 0.6 2.3 2 0 0 2 2 2 0 Putative aminopeptidase UCR_hinge PF02320.16 KND88177.1 - 2.3e-27 95.0 11.1 2.3e-27 95.0 11.1 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein Ribonuc_red_lgC PF02867.15 KND88177.1 - 0.035 12.7 2.8 0.039 12.5 2.8 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain BUD22 PF09073.10 KND88177.1 - 0.17 11.2 15.5 0.19 11.0 15.5 1.0 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KND88177.1 - 0.65 8.1 18.5 0.72 8.0 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 KND88177.1 - 0.94 9.0 8.9 1 8.8 8.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tim54 PF11711.8 KND88177.1 - 1.2 7.8 10.8 1.4 7.6 10.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3c_N PF05470.12 KND88177.1 - 2.4 6.4 11.5 2.6 6.2 11.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RPN2_C PF18004.1 KND88177.1 - 2.7 7.9 12.1 3.6 7.5 12.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 KND88177.1 - 3.7 5.7 12.3 4.1 5.6 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KND88177.1 - 3.7 6.4 5.3 3.9 6.4 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GET2 PF08690.10 KND88177.1 - 5.3 6.6 6.1 6.5 6.3 6.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 SAPS PF04499.15 KND88177.1 - 5.8 5.6 7.1 6.4 5.4 7.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 KND88177.1 - 9.5 4.2 25.9 11 3.9 25.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KND88178.1 - 9.2e-24 84.0 38.2 6.9e-22 77.9 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_psq PF05225.16 KND88178.1 - 0.15 11.8 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain DND1_DSRM PF14709.7 KND88179.1 - 0.0036 17.5 0.0 0.0055 16.9 0.0 1.4 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KND88179.1 - 0.0081 16.8 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif NTP_transferase PF00483.23 KND88180.1 - 2e-52 178.3 0.0 4.3e-52 177.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KND88180.1 - 1.4e-14 53.1 7.8 1.2e-10 40.7 1.4 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KND88180.1 - 1e-09 38.9 0.0 1.4e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KND88180.1 - 3.8e-07 29.7 10.8 4.2e-07 29.6 0.7 3.5 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KND88180.1 - 0.0014 16.9 0.1 0.0039 15.4 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 KND88180.1 - 0.014 15.4 0.0 0.03 14.2 0.0 1.5 2 0 0 2 2 2 0 Cytidylyltransferase RNA_ligase PF09414.10 KND88181.1 - 3.6e-28 98.9 0.0 5.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 RNA ligase RTA1 PF04479.13 KND88182.1 - 2.8e-14 53.2 2.4 2.8e-14 53.2 2.4 1.5 2 0 0 2 2 2 1 RTA1 like protein DPM2 PF07297.12 KND88182.1 - 0.27 11.6 9.7 4.1 7.8 9.6 2.2 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-CHY PF05495.12 KND88184.1 - 4.5e-11 43.1 8.7 4.5e-11 43.1 8.7 3.4 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 KND88184.1 - 0.00071 19.9 0.0 0.0066 16.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain Cwf_Cwc_15 PF04889.12 KND88184.1 - 0.036 13.8 1.7 0.067 12.9 1.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AMP-binding PF00501.28 KND88185.1 - 6.7e-82 275.3 0.0 9.1e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND88185.1 - 0.018 16.0 1.0 0.054 14.5 0.7 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain PAN_3 PF08277.12 KND88185.1 - 0.069 13.0 0.1 0.2 11.5 0.1 1.8 1 0 0 1 1 1 0 PAN-like domain DUF3295 PF11702.8 KND88186.1 - 4e-148 494.9 35.7 2e-147 492.6 35.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KND88186.1 - 1.6e-12 47.0 1.4 3.3e-12 46.0 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VHS PF00790.19 KND88187.1 - 3.9e-41 140.2 2.2 2.5e-40 137.6 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KND88187.1 - 3.2e-15 56.0 2.9 5.7e-15 55.2 2.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 KND88187.1 - 0.00093 19.5 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KND88187.1 - 0.0023 17.7 18.2 0.0027 17.5 1.5 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KND88187.1 - 0.082 13.1 2.0 0.19 12.0 2.0 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.22 KND88187.1 - 0.1 12.5 4.7 0.19 11.7 4.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NTPase_I-T PF01931.18 KND88187.1 - 0.14 12.0 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF84 Fer4_2 PF12797.7 KND88187.1 - 2.2 8.6 7.5 4.7 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 KND88188.1 - 4.1e-34 118.3 0.0 6e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND88188.1 - 6.9e-14 52.1 0.0 9.5e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KND88188.1 - 1.4e-08 35.2 0.0 3.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Lactonase PF10282.9 KND88189.1 - 9.6e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 KND88190.1 - 2.7e-42 144.3 0.0 3.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KND88190.1 - 1.8e-25 88.5 0.1 2.7e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KND88190.1 - 0.072 13.4 0.0 0.57 10.5 0.0 2.3 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain RraA-like PF03737.15 KND88191.1 - 3.6e-24 85.6 0.0 4.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA Vps36_ESCRT-II PF11605.8 KND88192.1 - 0.0051 17.0 0.0 0.043 14.0 0.0 2.1 1 1 1 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.6 KND88192.1 - 0.045 14.1 0.0 0.09 13.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial PH domain GTP1_OBG PF01018.22 KND88193.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 GTP1/OBG Glyoxalase PF00903.25 KND88194.1 - 2.1e-39 134.6 0.1 1.2e-18 67.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KND88194.1 - 7.4e-15 55.2 0.1 5e-06 26.7 0.0 4.0 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KND88194.1 - 3.1e-07 31.1 0.0 0.0042 17.9 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KND88194.1 - 9.4e-06 25.6 0.8 0.044 13.7 0.0 4.2 2 2 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KND88194.1 - 0.00018 21.7 0.0 0.72 9.9 0.0 3.3 1 1 1 3 3 3 2 Glyoxalase-like domain MoaF PF10703.9 KND88194.1 - 0.051 13.5 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain Pfk_N PF18468.1 KND88194.1 - 0.053 14.0 0.2 5.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast CppA_N PF14506.6 KND88194.1 - 0.08 13.0 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal 2-Hacid_dh_C PF02826.19 KND88195.1 - 6.7e-54 181.9 0.1 1.2e-53 181.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND88195.1 - 9.1e-34 116.0 0.3 1.7e-33 115.1 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KND88195.1 - 8.1e-05 22.3 0.5 0.0021 17.8 0.0 2.7 2 0 0 2 2 2 1 ACT domain AlaDh_PNT_C PF01262.21 KND88195.1 - 0.0069 15.7 1.1 0.014 14.7 1.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 KND88195.1 - 0.0072 16.8 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain DUF21 PF01595.20 KND88196.1 - 1.2e-34 119.5 0.1 1.8e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KND88196.1 - 6.3e-05 23.3 0.7 0.034 14.6 0.0 3.1 2 1 0 2 2 2 2 CBS domain Pkinase PF00069.25 KND88197.1 - 2.1e-05 24.0 0.0 0.081 12.3 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Sec63 PF02889.16 KND88199.1 - 2.8e-14 52.9 0.0 3.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain HHH_5 PF14520.6 KND88199.1 - 0.0058 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 KND88199.1 - 0.039 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Acetyltransf_1 PF00583.25 KND88201.1 - 4.3e-08 33.4 0.0 6.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND88201.1 - 2.9e-06 27.6 0.0 4.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND88201.1 - 3.1e-06 27.1 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND88201.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KND88201.1 - 0.011 15.8 0.1 0.022 14.8 0.1 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND88202.1 - 1.2e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND88202.1 - 1.7e-06 28.3 0.0 2.2e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND88202.1 - 2e-06 28.1 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND88202.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND88202.1 - 0.012 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 KND88202.1 - 0.055 13.6 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Tyrosinase PF00264.20 KND88203.1 - 2e-30 106.7 1.3 3.8e-27 96.0 0.4 2.4 2 0 0 2 2 2 2 Common central domain of tyrosinase Tyosinase_C PF18132.1 KND88203.1 - 0.00034 21.3 0.0 0.0022 18.7 0.0 2.2 1 1 0 1 1 1 1 Tyosinase C-terminal domain zf-primase PF09329.11 KND88204.1 - 6.3e-18 64.3 1.9 1.2e-17 63.4 1.9 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 KND88204.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF5551 PF17705.1 KND88205.1 - 0.095 12.3 1.1 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5551) Inositol_P PF00459.25 KND88207.1 - 1.3e-51 175.8 0.8 2.5e-51 174.8 0.8 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family ABC_tran PF00005.27 KND88208.1 - 4.9e-47 159.9 0.3 4.5e-22 79.1 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 KND88208.1 - 2.2e-19 69.3 8.3 2.2e-19 69.3 8.3 3.4 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 KND88208.1 - 2e-16 60.7 5.1 0.0002 21.3 0.0 4.6 5 0 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND88208.1 - 4.2e-10 39.4 3.9 0.0062 16.0 0.0 4.8 5 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KND88208.1 - 1.2e-06 28.5 0.1 0.039 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KND88208.1 - 9.8e-06 26.0 0.7 0.035 14.5 0.2 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KND88208.1 - 1.1e-05 25.0 0.3 0.23 11.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KND88208.1 - 1.5e-05 24.8 0.5 0.0018 18.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KND88208.1 - 1.6e-05 25.5 1.0 0.44 11.1 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.6 KND88208.1 - 1.8e-05 25.3 15.3 0.005 17.4 0.0 4.5 5 0 0 5 5 4 2 AAA domain AAA_24 PF13479.6 KND88208.1 - 1.9e-05 24.5 0.5 0.8 9.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KND88208.1 - 6.4e-05 23.3 0.1 0.28 11.5 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KND88208.1 - 0.00014 22.2 0.7 0.39 10.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KND88208.1 - 0.00017 22.0 0.1 0.42 11.0 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KND88208.1 - 0.00018 21.5 2.2 0.16 11.8 0.1 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_33 PF13671.6 KND88208.1 - 0.00032 20.9 0.0 0.88 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 KND88208.1 - 0.0019 17.3 0.1 1.5 7.8 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KND88208.1 - 0.002 18.1 0.1 2.4 8.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 KND88208.1 - 0.0032 17.5 0.0 2.4 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KND88208.1 - 0.004 17.1 0.1 0.4 10.6 0.1 2.8 3 0 0 3 3 2 1 NTPase Roc PF08477.13 KND88208.1 - 0.0061 16.8 0.3 3.2 8.0 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 KND88208.1 - 0.0067 16.2 16.1 0.088 12.5 0.0 4.6 4 1 0 5 5 5 2 AAA ATPase domain Dynamin_N PF00350.23 KND88208.1 - 0.0094 16.0 2.8 6.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Dynamin family ATP-synt_ab PF00006.25 KND88208.1 - 0.0094 15.6 0.0 0.58 9.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 KND88208.1 - 0.011 15.7 0.6 0.36 10.7 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 KND88208.1 - 0.013 15.1 0.9 1 8.9 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 KND88208.1 - 0.016 15.6 0.1 8.2 6.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KND88208.1 - 0.017 14.4 0.1 3.2 6.9 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 KND88208.1 - 0.026 14.0 0.1 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KND88208.1 - 0.027 14.5 0.4 7.6 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KND88208.1 - 0.045 13.7 0.8 8.6 6.2 0.0 3.2 4 0 0 4 4 3 0 Rad17 P-loop domain TsaE PF02367.17 KND88208.1 - 0.053 13.5 0.1 9.2 6.3 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KND88208.1 - 0.055 13.7 1.8 4.5 7.6 0.5 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 KND88208.1 - 0.073 12.7 5.7 4.3 6.9 0.0 3.6 4 1 1 5 5 4 0 AAA domain SRP54 PF00448.22 KND88208.1 - 0.13 11.9 1.9 2.3 7.8 0.0 3.0 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Arf PF00025.21 KND88208.1 - 0.22 10.9 1.4 2.1 7.8 0.1 2.6 3 0 0 3 3 2 0 ADP-ribosylation factor family Thymidylate_kin PF02223.17 KND88208.1 - 0.25 11.0 2.8 1.5 8.5 0.0 3.4 3 0 0 3 3 2 0 Thymidylate kinase DUF2813 PF11398.8 KND88208.1 - 0.66 9.2 3.1 0.31 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_17 PF13207.6 KND88208.1 - 1.4 9.4 5.5 24 5.3 0.2 3.9 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 KND88208.1 - 1.7 8.7 0.0 1.7 8.7 0.0 3.8 5 0 0 5 5 4 0 Helicase HerA, central domain ATPase_2 PF01637.18 KND88208.1 - 9.3 6.1 7.1 8.8 6.2 0.0 3.4 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Spermine_synth PF01564.17 KND88209.1 - 3e-05 23.5 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 KND88209.1 - 0.0098 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.18 KND88210.1 - 8e-21 74.3 0.1 1.7e-20 73.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88210.1 - 0.049 13.8 5.9 0.1 12.8 5.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_2 PF01909.23 KND88210.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pyridox_ox_2 PF12900.7 KND88212.1 - 8.6e-38 129.5 0.0 1.2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Metaviral_G PF09595.10 KND88213.1 - 0.08 13.0 2.1 0.12 12.4 2.1 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein Fungal_trans_2 PF11951.8 KND88214.1 - 2.5e-11 43.0 0.0 3.9e-11 42.4 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Evr1_Alr PF04777.13 KND88216.1 - 0.00028 21.3 0.2 0.00054 20.4 0.2 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Cas_Csy2 PF09614.10 KND88217.1 - 0.085 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) MFS_1 PF07690.16 KND88218.1 - 3.6e-22 78.8 27.9 3.2e-15 55.9 11.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily F_bP_aldolase PF01116.20 KND88220.1 - 1e-86 290.9 0.0 1.1e-86 290.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Dabb PF07876.12 KND88221.1 - 2.3e-10 41.0 0.3 3.9e-10 40.2 0.3 1.4 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Ldh_2 PF02615.14 KND88222.1 - 6.3e-112 374.0 0.5 7.5e-112 373.8 0.5 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase RraA-like PF03737.15 KND88223.1 - 3.5e-31 108.4 0.0 4.4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA AMP-binding PF00501.28 KND88227.1 - 6.8e-74 248.9 0.0 9e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KND88227.1 - 2.2e-16 59.5 0.4 6e-16 58.1 0.1 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KND88227.1 - 1.1e-15 58.4 0.0 2.5e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_12 PF08242.12 KND88228.1 - 1.8e-18 67.1 0.0 6.9e-18 65.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND88228.1 - 1.9e-11 44.0 0.0 4.5e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND88228.1 - 2.7e-11 44.0 0.0 1.4e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND88228.1 - 3.5e-10 40.4 0.0 9.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND88228.1 - 2.2e-09 37.3 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.14 KND88228.1 - 8.3e-09 35.1 0.0 8.2e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KND88228.1 - 1.6e-08 33.4 0.1 3.2e-07 29.2 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Ubie_methyltran PF01209.18 KND88228.1 - 1.8e-07 30.7 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAD_binding_8 PF13450.6 KND88228.1 - 3.8e-06 27.0 0.0 0.0001 22.4 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Methyltransf_16 PF10294.9 KND88228.1 - 3.5e-05 23.6 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Pyr_redox_3 PF13738.6 KND88228.1 - 0.00027 20.3 0.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase PCMT PF01135.19 KND88228.1 - 0.0094 15.7 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 KND88228.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase 2-Hacid_dh_C PF02826.19 KND88228.1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DREV PF05219.12 KND88228.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Zn_clus PF00172.18 KND88229.1 - 1.1e-07 31.9 6.8 2.2e-07 30.8 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND88229.1 - 6.9e-06 25.1 0.1 1.1e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AhpC-TSA PF00578.21 KND88230.1 - 5.4e-30 103.8 0.0 7.2e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND88230.1 - 9.9e-12 44.8 0.0 1.4e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KND88230.1 - 1.7e-09 37.4 0.1 3.3e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DIOX_N PF14226.6 KND88231.1 - 2.5e-21 76.6 0.0 1.1e-17 64.9 0.0 2.4 1 1 1 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND88231.1 - 1.3e-17 64.1 0.0 2.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KND88232.1 - 9.8e-23 80.6 78.1 6.7e-21 74.6 43.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2407_C PF13373.6 KND88232.1 - 3.7 7.7 6.6 0.56 10.4 0.5 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain Amidase PF01425.21 KND88234.1 - 1.6e-100 337.3 0.0 5.4e-100 335.5 0.0 1.7 1 1 0 1 1 1 1 Amidase ADH_N PF08240.12 KND88235.1 - 2.4e-09 37.0 0.0 4.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND88235.1 - 2.6e-08 33.9 0.1 5.3e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KND88235.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_transf_90 PF05686.12 KND88236.1 - 1.2e-11 44.2 0.5 9.5e-10 37.9 0.3 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.18 KND88237.1 - 1.4e-14 53.8 0.5 2.4e-14 53.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88238.1 - 3.8e-10 39.7 7.6 5.2e-10 39.3 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 KND88239.1 - 2.6e-70 236.9 0.2 7.3e-70 235.4 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KND88239.1 - 5.9e-30 103.0 0.2 1.3e-28 98.7 0.0 3.0 3 0 0 3 3 3 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KND88239.1 - 4.7e-29 100.8 0.0 1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KND88239.1 - 9.3e-25 87.3 0.0 1.3e-23 83.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KND88239.1 - 2e-24 86.7 0.0 3.1e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KND88239.1 - 5.6e-14 52.5 0.3 3.7e-08 33.4 0.0 3.4 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 KND88239.1 - 2.1e-12 47.2 0.1 5e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KND88239.1 - 3.3e-11 43.8 0.0 1.2e-10 42.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 KND88239.1 - 8e-10 38.4 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 KND88239.1 - 6.1e-07 29.1 0.2 1.6e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 KND88239.1 - 9.3e-07 29.5 0.0 5e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KND88239.1 - 1.7e-06 28.4 0.0 4.8e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KND88239.1 - 3.2e-05 24.5 0.0 9.6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KND88239.1 - 0.00013 21.5 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 KND88239.1 - 0.00021 21.2 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND88239.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 KND88239.1 - 0.031 14.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 KND88239.1 - 0.039 13.1 0.0 0.47 9.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 KND88239.1 - 0.14 12.2 0.0 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF1033 PF06279.11 KND88239.1 - 0.59 10.3 1.6 1.4 9.1 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) FAD_binding_3 PF01494.19 KND88240.1 - 2.1e-19 70.0 2.4 8.8e-19 68.0 2.2 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND88240.1 - 0.0048 16.2 0.3 0.011 15.0 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND88240.1 - 0.019 15.5 1.2 0.019 15.5 1.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND88240.1 - 0.02 15.1 1.9 0.046 13.9 1.9 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 KND88240.1 - 0.029 13.4 0.0 0.19 10.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KND88240.1 - 2.6 7.6 8.3 1 8.9 5.0 2.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase Aldedh PF00171.22 KND88241.1 - 1.5e-110 369.9 1.1 4.8e-78 262.7 0.1 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DHDPS PF00701.22 KND88242.1 - 6.6e-62 208.8 0.0 7.5e-62 208.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CutC PF03932.14 KND88242.1 - 0.085 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 CutC family Dala_Dala_lig_C PF07478.13 KND88243.1 - 2.6e-09 36.9 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 KND88243.1 - 0.011 15.3 0.1 0.059 13.0 0.0 2.2 2 1 0 2 2 2 0 ATP-grasp domain CPSase_L_D2 PF02786.17 KND88243.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KND88243.1 - 0.039 14.0 0.0 0.075 13.1 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.16 KND88244.1 - 1.1e-07 31.2 3.3 1.8e-07 30.5 3.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.13 KND88244.1 - 0.00013 21.6 0.2 0.00017 21.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF998) TRI12 PF06609.13 KND88244.1 - 0.00046 18.7 0.7 0.00051 18.6 0.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4203 PF13886.6 KND88244.1 - 0.0021 17.8 0.2 0.0029 17.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) AA_permease PF00324.21 KND88244.1 - 0.021 13.4 0.5 0.025 13.2 0.5 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4079 PF13301.6 KND88244.1 - 0.042 14.0 2.3 0.27 11.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 KND88246.1 - 1.1e-27 97.0 22.7 1.1e-27 97.0 22.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KND88246.1 - 0.011 14.0 5.1 1.3 7.3 5.1 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3959 PF13105.6 KND88246.1 - 0.021 14.4 0.6 0.048 13.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Methyltransf_2 PF00891.18 KND88247.1 - 1.8e-17 63.3 0.1 4.7e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain GST_C PF00043.25 KND88248.1 - 4.5e-11 42.8 0.0 1e-10 41.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KND88248.1 - 1.2e-08 35.2 0.0 3.8e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND88248.1 - 1.2e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND88248.1 - 0.0005 20.2 0.0 0.0015 18.6 0.0 1.8 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND88248.1 - 0.05 14.0 0.0 0.088 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_23 PF13489.6 KND88249.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Beta_helix_2 PF18835.1 KND88249.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase APH PF01636.23 KND88251.1 - 7.6e-18 65.3 0.0 1.3e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88251.1 - 0.0053 16.4 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase PIG-S PF10510.9 KND88252.1 - 7.2e-158 526.6 0.0 9.7e-158 526.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S15 PF02129.18 KND88252.1 - 0.001 18.7 0.5 0.0027 17.4 0.5 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KND88252.1 - 0.016 14.5 0.3 0.29 10.3 0.2 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND88252.1 - 0.025 14.2 0.0 0.96 9.0 0.0 3.0 3 1 0 3 3 3 0 alpha/beta hydrolase fold 3HBOH PF10605.9 KND88252.1 - 0.025 12.8 0.0 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Peptidase_S9 PF00326.21 KND88252.1 - 0.064 12.7 0.3 1.1 8.6 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family F-box PF00646.33 KND88253.1 - 0.023 14.5 0.0 0.071 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain Kelch_3 PF13415.6 KND88254.1 - 1.2e-13 51.0 6.0 7.5e-09 35.7 0.0 6.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.6 KND88254.1 - 1.6e-12 47.2 0.0 0.0032 17.5 0.0 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KND88254.1 - 3e-12 46.2 0.8 0.0012 18.8 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KND88254.1 - 8.1e-12 45.0 2.5 0.0022 18.2 0.0 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KND88254.1 - 1.3e-10 40.7 0.0 0.038 13.6 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 KND88254.1 - 6.3e-09 35.5 0.1 0.00033 20.5 0.0 4.4 5 0 0 5 5 5 2 Kelch motif BTB PF00651.31 KND88254.1 - 0.086 13.1 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.28 KND88255.1 - 3.5e-73 246.6 0.0 4.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND88255.1 - 1.7e-07 32.1 0.0 4.5e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.7 KND88256.1 - 7.5e-07 30.0 0.7 1.4e-06 29.1 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND88256.1 - 1.9e-05 24.5 0.0 0.0014 18.4 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND88256.1 - 0.0027 17.2 0.1 0.011 15.2 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KND88256.1 - 0.0038 16.9 0.0 0.018 14.7 0.0 2.1 2 1 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 KND88256.1 - 0.038 13.3 0.0 0.094 12.0 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 KND88256.1 - 0.095 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family AMP-binding PF00501.28 KND88257.1 - 1.4e-72 244.6 0.0 5.4e-72 242.7 0.0 2.0 3 0 0 3 3 3 1 AMP-binding enzyme Condensation PF00668.20 KND88257.1 - 5.7e-70 236.3 0.2 8.9e-70 235.6 0.2 1.3 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 KND88257.1 - 4.9e-69 232.7 0.0 8.5e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KND88257.1 - 2.8e-53 180.5 0.2 3.1e-52 177.1 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KND88257.1 - 1.8e-51 175.2 0.0 3.1e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KND88257.1 - 8.2e-37 127.4 0.0 2.5e-36 125.8 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 KND88257.1 - 1.5e-32 112.8 0.0 5.6e-32 110.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 KND88257.1 - 3.1e-31 107.8 0.0 9.3e-31 106.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KND88257.1 - 2.5e-17 63.0 3.0 2.8e-10 40.4 0.2 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site Epimerase PF01370.21 KND88257.1 - 1.6e-12 47.4 0.1 1.3e-08 34.7 0.0 2.8 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KND88257.1 - 7.2e-12 45.2 0.0 4.8e-09 36.0 0.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 KND88257.1 - 1.2e-11 45.0 0.0 7.9e-11 42.4 0.0 2.5 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KND88257.1 - 1.7e-05 25.4 0.1 0.00053 20.6 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.19 KND88257.1 - 2.1e-05 23.7 0.0 0.00054 19.0 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_12 PF08242.12 KND88257.1 - 0.00066 20.4 0.0 0.0021 18.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KND88257.1 - 0.0038 16.6 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 KND88257.1 - 0.0043 17.7 0.1 0.033 14.8 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 KND88257.1 - 0.012 15.1 0.0 0.52 9.7 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_23 PF13489.6 KND88257.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 KND88257.1 - 0.14 11.3 0.0 6.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PIF1 PF05970.14 KND88258.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase APH PF01636.23 KND88259.1 - 1.8e-13 51.0 0.0 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88259.1 - 0.0062 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase AXE1 PF05448.12 KND88259.1 - 0.007 15.1 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 KND88259.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CoA_transf_3 PF02515.17 KND88260.1 - 0.16 11.1 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III Choline_kinase PF01633.20 KND88261.1 - 0.024 14.2 0.9 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase Apis_Csd PF11671.8 KND88261.1 - 0.31 11.1 1.2 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Complementary sex determiner protein MFS_1 PF07690.16 KND88262.1 - 4.3e-38 131.1 65.9 9.6e-38 130.0 45.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KND88262.1 - 1.3e-17 63.5 14.7 2.7e-17 62.4 14.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND88262.1 - 4.2e-10 39.1 26.7 3.3e-09 36.1 14.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3336 PF11815.8 KND88263.1 - 1.2e-35 122.2 0.2 2.2e-35 121.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND88263.1 - 1.2e-20 74.6 0.0 2.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase EcoEI_R_C PF08463.10 KND88264.1 - 0.22 11.6 1.0 24 5.0 0.1 2.5 1 1 1 2 2 2 0 EcoEI R protein C-terminal Chromo PF00385.24 KND88266.1 - 8.2e-09 35.2 1.7 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Drc1-Sld2 PF11719.8 KND88266.1 - 0.002 17.8 0.5 0.0022 17.6 0.5 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein MFS_1 PF07690.16 KND88267.1 - 6.8e-31 107.5 36.1 1.2e-30 106.7 36.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.23 KND88267.1 - 1.9e-08 34.5 1.9 2.7e-07 30.7 1.9 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88267.1 - 0.0094 15.5 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ketoacyl-synt PF00109.26 KND88269.1 - 8.3e-79 264.7 0.0 2e-78 263.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KND88269.1 - 2.5e-66 223.9 8.1 2.8e-66 223.7 5.1 2.7 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KND88269.1 - 5.9e-42 144.3 0.0 3.5e-41 141.7 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND88269.1 - 2.4e-33 114.6 0.3 5.2e-33 113.6 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KND88269.1 - 9.5e-16 57.9 0.0 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KND88269.1 - 1.9e-15 57.0 1.7 4.4e-15 55.8 1.7 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KND88269.1 - 5e-07 30.2 0.0 1.4e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KND88269.1 - 2.1e-05 24.0 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KND88269.1 - 0.056 13.3 0.3 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EthD PF07110.11 KND88270.1 - 2.5e-18 67.0 2.2 3.1e-18 66.7 2.2 1.1 1 0 0 1 1 1 1 EthD domain LPD38 PF18857.1 KND88270.1 - 0.08 13.1 0.0 0.093 12.9 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein associated domain 38 MFS_1 PF07690.16 KND88271.1 - 2.1e-37 128.9 50.6 9.6e-32 110.3 25.5 3.1 2 1 2 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND88271.1 - 0.00012 21.1 36.3 0.023 13.6 13.2 4.0 2 2 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KND88271.1 - 0.007 14.7 1.3 0.007 14.7 1.3 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family P5-ATPase PF12409.8 KND88271.1 - 0.067 13.3 0.1 0.39 10.8 0.1 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter Peptidase_M48_N PF16491.5 KND88271.1 - 0.19 11.6 2.9 0.63 9.9 2.9 2.0 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices SirB PF04247.12 KND88271.1 - 4 7.5 9.8 6.3 6.9 2.5 3.5 3 1 0 3 3 3 0 Invasion gene expression up-regulator, SirB Cu-oxidase_2 PF07731.14 KND88272.1 - 9.3e-11 41.6 0.2 9.9e-11 41.5 0.2 1.1 1 0 0 1 1 1 1 Multicopper oxidase HTH_51 PF18558.1 KND88273.1 - 3.1e-24 84.7 0.0 5.5e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 KND88273.1 - 3e-14 53.5 0.0 5.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KND88273.1 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KND88273.1 - 2.1e-08 34.2 0.0 1e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND88273.1 - 2.8e-08 34.4 0.0 5.3e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND88273.1 - 2.1e-05 25.1 0.0 5.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND88273.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3494 PF11999.8 KND88274.1 - 5e-65 219.1 16.3 5e-65 219.1 16.3 4.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3494) Caps_synth PF05704.12 KND88275.1 - 1.6e-19 70.4 0.1 2.9e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KND88275.1 - 1.2e-06 29.0 0.0 3.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Aminotran_3 PF00202.21 KND88276.1 - 5.7e-103 344.7 0.0 7e-103 344.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Nif11 PF07862.11 KND88276.1 - 0.014 15.7 0.0 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Nif11 domain NAD_binding_10 PF13460.6 KND88277.1 - 4.6e-07 29.9 0.1 9.6e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND88277.1 - 1.1e-06 28.3 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND88277.1 - 3.8e-05 23.4 0.0 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 KND88277.1 - 0.0045 16.0 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KND88277.1 - 0.02 14.1 0.0 0.081 12.1 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Aldedh PF00171.22 KND88278.1 - 2.1e-178 593.6 0.1 2.4e-178 593.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aa_trans PF01490.18 KND88279.1 - 5.5e-28 97.8 22.5 4e-21 75.2 10.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4059 PF13268.6 KND88279.1 - 0.41 11.1 2.9 12 6.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF3040 PF11239.8 KND88279.1 - 7.4 6.9 20.2 4.7 7.6 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3040) SIR2 PF02146.17 KND88281.1 - 8.6e-21 74.6 0.1 1.1e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Sir2 family Pro_racemase PF05544.11 KND88282.1 - 1.2e-113 379.5 0.0 1.4e-113 379.3 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 KND88282.1 - 0.068 12.6 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein Fic PF02661.18 KND88283.1 - 3.1e-07 31.2 0.2 1.6e-06 28.9 0.1 1.9 2 0 0 2 2 2 1 Fic/DOC family HSP33 PF01430.19 KND88283.1 - 0.087 12.2 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Hsp33 protein GSIII_N PF12437.8 KND88283.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Zn_clus PF00172.18 KND88284.1 - 6.9e-09 35.7 10.5 1.1e-08 35.0 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND88284.1 - 0.024 13.7 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KND88284.1 - 0.031 14.4 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Dak1 PF02733.17 KND88285.1 - 1e-96 323.6 0.0 1.4e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KND88285.1 - 6.2e-42 143.4 2.1 9.3e-42 142.9 2.1 1.3 1 0 0 1 1 1 1 DAK2 domain PhyH PF05721.13 KND88286.1 - 3.3e-20 73.2 0.0 4.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 KND88286.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_34 PF05637.12 KND88288.1 - 1.3e-13 51.3 0.1 5e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KND88288.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Ferric_reduct PF01794.19 KND88289.1 - 6.3e-22 78.0 11.0 1.3e-21 77.0 11.0 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND88289.1 - 2e-05 24.8 0.2 0.17 12.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KND88289.1 - 0.00054 20.6 0.1 0.0025 18.4 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 KND88289.1 - 0.0013 18.8 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain Dabb PF07876.12 KND88290.1 - 9.3e-24 83.9 0.0 1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Sulfatase PF00884.23 KND88291.1 - 7.4e-19 68.3 0.1 1.7e-17 63.8 0.1 2.3 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KND88291.1 - 9.4e-05 22.2 0.1 0.00026 20.7 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KND88291.1 - 0.0044 15.7 0.0 0.006 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) p450 PF00067.22 KND88292.1 - 3.8e-66 223.8 0.0 4.3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LigT_PEase PF02834.16 KND88292.1 - 0.11 12.7 0.5 0.48 10.6 0.1 2.2 2 1 0 2 2 2 0 LigT like Phosphoesterase PhyH PF05721.13 KND88293.1 - 5.9e-21 75.7 0.0 7.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 KND88294.1 - 4.1e-119 398.4 25.8 4.9e-119 398.1 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND88294.1 - 4e-18 65.5 34.5 4e-18 65.5 34.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 KND88294.1 - 0.22 11.3 1.8 3.6 7.4 0.3 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term UbiA PF01040.18 KND88295.1 - 2.1e-10 40.3 1.6 2.4e-10 40.1 1.6 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2627 PF11118.8 KND88295.1 - 0.063 13.9 0.1 0.65 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2627) DUF4027 PF13219.6 KND88295.1 - 0.12 12.3 1.0 0.28 11.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DAO PF01266.24 KND88296.1 - 2.3e-29 103.1 1.5 3.3e-29 102.6 1.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND88296.1 - 4.8e-05 23.5 0.3 0.00015 21.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND88296.1 - 0.00045 19.5 0.4 0.00045 19.5 0.4 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KND88296.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND88296.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND88296.1 - 0.0097 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KND88296.1 - 0.024 15.2 0.5 0.062 13.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EthD PF07110.11 KND88297.1 - 2e-16 60.9 0.8 2.8e-16 60.4 0.8 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KND88297.1 - 0.0071 16.8 0.5 0.019 15.4 0.5 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Methyltransf_23 PF13489.6 KND88298.1 - 2.9e-11 43.5 0.0 3.9e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND88298.1 - 0.0033 18.1 0.0 0.017 15.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND88298.1 - 0.0046 17.7 0.0 0.014 16.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND88298.1 - 0.034 14.8 0.0 0.091 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KND88298.1 - 0.14 11.9 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 KND88299.1 - 5.2e-64 216.7 0.0 6.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 KND88300.1 - 7.5e-10 38.9 0.2 1.8e-08 34.3 0.6 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND88300.1 - 1.4e-09 37.6 0.1 4.9e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND88300.1 - 5.1e-07 30.5 3.8 5.1e-07 30.5 3.8 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 KND88300.1 - 0.004 16.7 0.1 0.03 13.9 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 KND88300.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 KND88300.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Esterase PF00756.20 KND88300.1 - 0.22 11.1 0.1 0.35 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_M24 PF00557.24 KND88301.1 - 2.3e-38 132.0 0.0 3.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CCDC106 PF15794.5 KND88301.1 - 0.13 11.9 4.0 0.27 10.9 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 REV PF00424.18 KND88301.1 - 0.24 11.4 1.2 0.81 9.8 0.1 2.1 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) PGA2 PF07543.12 KND88301.1 - 5.3 7.0 10.2 0.22 11.5 3.9 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Peptidase_M24 PF00557.24 KND88302.1 - 2.1e-44 151.7 0.0 2.6e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KND88302.1 - 3e-21 75.4 6.0 7.2e-21 74.2 6.0 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KND88302.1 - 0.00025 21.0 4.5 0.00066 19.7 4.5 1.7 1 0 0 1 1 1 1 MYND finger GMC_oxred_C PF05199.13 KND88307.1 - 0.01 16.4 0.0 0.013 16.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FMN_dh PF01070.18 KND88308.1 - 0.012 14.6 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase NmrA PF05368.13 KND88309.1 - 1.3e-55 188.5 0.8 1.7e-55 188.1 0.8 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND88309.1 - 8.1e-20 71.5 0.3 1.1e-19 71.1 0.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND88309.1 - 0.0055 15.8 0.1 0.0079 15.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Nitro_FeMo-Co PF02579.17 KND88309.1 - 0.076 13.3 0.2 0.22 11.9 0.2 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor ERAP1_C PF11838.8 KND88310.1 - 4.5e-89 299.1 0.0 1.2e-88 297.7 0.0 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KND88310.1 - 3e-85 285.2 0.5 5.3e-85 284.4 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KND88310.1 - 1.3e-50 172.2 0.7 6e-50 170.0 0.4 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Fasciclin PF02469.22 KND88312.1 - 1.2e-46 158.1 0.0 6.4e-26 91.1 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain T7SS_ESX_EspC PF10824.8 KND88312.1 - 0.045 14.2 0.9 0.78 10.2 0.3 2.8 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm AphA_like PF14557.6 KND88312.1 - 0.055 13.2 0.0 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator SNF PF00209.18 KND88313.1 - 0.00017 20.5 0.5 0.00018 20.4 0.5 1.0 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Phage_holin_2_4 PF16082.5 KND88313.1 - 0.17 11.6 1.1 0.25 11.1 1.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like AA_permease_2 PF13520.6 KND88314.1 - 9.4e-67 225.7 53.6 1.1e-66 225.4 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND88314.1 - 1.3e-32 113.1 49.1 1.6e-32 112.8 49.1 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 KND88314.1 - 0.88 9.6 4.8 9.4 6.3 0.0 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Fungal_trans_2 PF11951.8 KND88315.1 - 2e-34 119.1 5.0 2e-33 115.8 5.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88315.1 - 1.9e-07 31.1 12.3 2.9e-07 30.5 12.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase PF00117.28 KND88316.1 - 8.8e-14 51.7 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KND88316.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KND88316.1 - 0.0003 20.6 0.1 0.0091 15.8 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KND88316.1 - 0.0044 16.8 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 KND88317.1 - 3.8e-33 114.9 21.1 3.8e-33 114.9 21.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND88317.1 - 2.7e-05 23.6 0.9 2.7e-05 23.6 0.9 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Spin-Ssty PF02513.17 KND88317.1 - 0.086 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Spin/Ssty Family PgaD PF13994.6 KND88317.1 - 4.8 7.2 10.9 5.6 7.0 2.3 3.0 1 1 0 2 2 2 0 PgaD-like protein Fungal_trans_2 PF11951.8 KND88318.1 - 1.7e-11 43.5 0.4 8.1e-05 21.6 0.0 2.4 1 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88318.1 - 3.1e-06 27.2 6.2 7.4e-06 26.0 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2127 PF09900.9 KND88318.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) DUF5127 PF17168.4 KND88319.1 - 5.9e-79 265.0 4.7 8.7e-79 264.5 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KND88319.1 - 1e-70 236.9 0.1 1.9e-70 236.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KND88319.1 - 4.7e-61 206.1 3.4 6.6e-61 205.6 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KND88319.1 - 1.9e-05 24.1 2.6 2.7e-05 23.6 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4964) MFS_1 PF07690.16 KND88320.1 - 2.7e-30 105.5 36.1 2.7e-30 105.5 36.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KND88320.1 - 0.12 12.1 4.1 0.3 10.8 4.1 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF1616 PF07760.11 KND88320.1 - 0.39 10.1 1.6 0.96 8.8 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Sec1 PF00995.23 KND88321.1 - 2.7e-127 426.4 0.0 3.1e-127 426.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-CCCH_4 PF18044.1 KND88322.1 - 1.4e-08 34.4 2.8 2.1e-08 33.7 2.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KND88322.1 - 3.7e-06 26.8 5.8 6.2e-06 26.1 5.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KND88322.1 - 5.4e-05 23.0 2.7 9.8e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KND88322.1 - 0.0033 17.6 0.2 0.0068 16.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KND88322.1 - 0.025 15.0 2.4 0.042 14.3 2.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KND88322.1 - 0.28 11.9 5.0 0.1 13.3 0.5 2.6 2 0 0 2 2 2 0 Torus domain Filament PF00038.21 KND88324.1 - 0.00049 19.8 15.5 0.00049 19.8 15.5 4.9 3 1 2 6 6 6 2 Intermediate filament protein ATG16 PF08614.11 KND88324.1 - 0.0023 18.2 22.9 0.0023 18.2 22.9 5.1 2 1 2 4 4 4 2 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 KND88324.1 - 0.0037 17.3 6.4 0.0037 17.3 6.4 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF1664) Shugoshin_N PF07558.11 KND88324.1 - 0.025 14.4 1.8 0.025 14.4 1.8 6.1 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region DUF5595 PF18077.1 KND88324.1 - 0.066 13.3 0.5 0.066 13.3 0.5 6.4 7 1 1 8 8 8 0 Domain of unknown function (DUF5595) CCDC92 PF14916.6 KND88324.1 - 0.34 10.7 0.1 0.34 10.7 0.1 3.5 6 0 0 6 6 6 0 Coiled-coil domain of unknown function FlaC_arch PF05377.11 KND88324.1 - 0.99 9.9 40.2 1.8 9.1 0.1 7.6 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 KND88324.1 - 1.4 6.9 49.8 0.24 9.5 14.9 2.7 2 1 1 3 3 3 0 HOOK protein CDPS PF16715.5 KND88324.1 - 3.9 7.1 9.8 8.5 6.0 8.5 2.3 1 1 0 1 1 1 0 Cyclodipeptide synthase DUF4200 PF13863.6 KND88324.1 - 4.7 7.6 74.6 0.05 14.0 7.1 7.1 5 1 2 7 7 7 0 Domain of unknown function (DUF4200) Iso_dh PF00180.20 KND88325.1 - 4.1e-72 243.2 0.0 4.9e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 KND88326.1 - 3.7e-40 139.1 1.8 2.1e-30 107.1 0.4 2.0 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling TMF_DNA_bd PF12329.8 KND88326.1 - 0.058 13.4 0.8 0.058 13.4 0.8 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AATase PF07247.12 KND88328.1 - 1e-14 54.0 0.0 2.1e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 KND88328.1 - 0.00034 19.4 0.4 0.022 13.4 0.2 2.1 2 0 0 2 2 2 2 Condensation domain Serglycin PF04360.12 KND88329.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Serglycin AA_permease PF00324.21 KND88330.1 - 8.6e-57 192.8 23.9 1.1e-56 192.5 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND88330.1 - 5.7e-16 58.4 20.4 6.8e-16 58.1 20.4 1.0 1 0 0 1 1 1 1 Amino acid permease ATG2_CAD PF13329.6 KND88331.1 - 2.5e-52 176.7 0.7 5e-52 175.7 0.7 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 KND88331.1 - 2.9e-30 104.5 0.1 1.7e-28 98.8 0.0 3.4 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 KND88331.1 - 0.0028 17.5 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KND88331.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Amino_oxidase PF01593.24 KND88332.1 - 1.5e-56 192.6 0.0 2.2e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND88332.1 - 6.4e-16 58.3 0.1 1.4e-15 57.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KND88332.1 - 6e-07 29.6 0.1 0.0022 18.0 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KND88332.1 - 9.4e-06 25.1 0.0 4.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND88332.1 - 2.7e-05 24.6 0.4 5.6e-05 23.6 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND88332.1 - 0.00019 21.1 4.8 0.00097 18.8 3.5 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND88332.1 - 0.003 16.7 1.5 0.016 14.3 0.5 2.2 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KND88332.1 - 0.0037 16.6 0.9 0.0057 15.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KND88332.1 - 0.0049 16.8 0.9 0.008 16.1 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KND88332.1 - 0.0068 15.1 0.1 0.048 12.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KND88332.1 - 0.0077 15.5 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KND88332.1 - 0.047 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_8 PF01501.20 KND88334.1 - 7.8e-07 28.9 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 OPT PF03169.15 KND88336.1 - 9.9e-142 473.7 48.1 1.2e-141 473.4 48.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans PF04082.18 KND88337.1 - 0.00015 20.9 0.3 0.0011 18.0 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain P4Ha_N PF08336.11 KND88337.1 - 0.0059 16.6 0.0 0.0081 16.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ADK PF00406.22 KND88339.1 - 2.1e-35 122.1 0.0 9.6e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 KND88339.1 - 9.1e-15 54.4 0.0 1.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KND88339.1 - 5.5e-14 52.8 0.0 5.8e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND88339.1 - 0.00095 19.7 0.0 0.0038 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND88339.1 - 0.0022 18.2 0.0 0.017 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND88339.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ANTH PF07651.16 KND88340.1 - 4.9e-68 229.1 0.2 7.6e-68 228.5 0.2 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KND88340.1 - 5.1e-10 39.5 0.0 8.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 ENTH domain Mito_carr PF00153.27 KND88342.1 - 9.1e-38 128.1 4.5 1.6e-15 56.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 KND88343.1 - 2.3e-38 132.2 0.5 3.4e-38 131.6 0.5 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KND88343.1 - 9.2e-27 92.9 1.3 2.1e-26 91.7 1.3 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 KND88343.1 - 0.00039 21.1 0.3 0.0013 19.5 0.2 1.9 2 0 0 2 2 2 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 KND88343.1 - 0.14 12.6 0.0 0.43 11.1 0.1 1.8 2 0 0 2 2 2 0 N-terminal of Subtilase family BAR PF03114.18 KND88344.1 - 9.3e-05 22.2 4.0 0.0026 17.4 0.3 2.1 2 0 0 2 2 2 2 BAR domain Vps5 PF09325.10 KND88344.1 - 0.0012 18.4 0.7 0.0012 18.4 0.7 2.1 2 0 0 2 2 2 1 Vps5 C terminal like BAR_3 PF16746.5 KND88344.1 - 0.024 14.4 1.6 0.91 9.2 0.1 2.3 2 1 0 2 2 2 0 BAR domain of APPL family Spc7 PF08317.11 KND88344.1 - 3 6.6 6.7 0.23 10.3 1.2 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.15 KND88344.1 - 5.1 7.3 10.1 3.5 7.8 1.5 3.3 3 0 0 3 3 3 0 Basic region leucine zipper 2OG-FeII_Oxy PF03171.20 KND88345.1 - 1e-19 70.8 0.0 2.5e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KND88345.1 - 9.1e-14 52.2 0.0 1.5e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMG-CoA_red PF00368.18 KND88346.1 - 7.2e-139 462.9 2.8 9.9e-139 462.4 2.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KND88346.1 - 3.2e-50 170.0 0.2 5.4e-50 169.3 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KND88346.1 - 9.4e-14 51.5 8.1 2e-12 47.2 8.1 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KND88346.1 - 1.2e-09 36.9 4.8 1.8e-09 36.3 4.8 1.2 1 0 0 1 1 1 1 Patched family Isochorismatase PF00857.20 KND88347.1 - 2.2e-25 89.8 0.0 1.9e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Cauli_VI PF01693.16 KND88347.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Caulimovirus viroplasmin FumaraseC_C PF10415.9 KND88348.1 - 1.4e-21 76.7 0.1 2.9e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus LETM1 PF07766.13 KND88349.1 - 1.4e-103 346.0 1.8 1.4e-103 346.0 1.8 1.5 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KND88349.1 - 0.0096 15.7 0.0 0.78 9.6 0.0 3.2 3 0 0 3 3 3 1 SAP domain BPL_N PF09825.9 KND88349.1 - 0.16 11.0 1.8 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal MFS_1 PF07690.16 KND88350.1 - 0.00079 18.4 0.4 0.00082 18.4 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND88350.1 - 0.0099 14.8 0.0 0.0099 14.8 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Chitin_synth_1 PF01644.17 KND88351.1 - 1.3e-73 246.4 0.3 2.1e-73 245.7 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KND88351.1 - 1.1e-27 95.8 0.1 2.3e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KND88351.1 - 5e-23 81.5 0.7 3.2e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KND88351.1 - 1.9e-08 34.5 0.5 1.9e-08 34.5 0.5 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 FYVE PF01363.21 KND88352.1 - 0.006 16.7 4.7 0.006 16.7 4.7 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-piccolo PF05715.13 KND88352.1 - 2.6 8.2 8.8 0.59 10.3 2.5 2.6 2 0 0 2 2 2 0 Piccolo Zn-finger SnoaL_2 PF12680.7 KND88356.1 - 0.00017 22.2 1.3 0.00047 20.7 0.3 2.2 2 0 0 2 2 2 1 SnoaL-like domain Glyco_transf_25 PF01755.17 KND88357.1 - 9.7e-10 38.6 0.0 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Mucin PF01456.17 KND88358.1 - 0.033 14.2 14.9 0.037 14.0 14.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.8 KND88358.1 - 7.4 5.7 14.5 9.2 5.3 14.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3455 PF11937.8 KND88359.1 - 2.7e-28 99.4 0.0 3.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Hexapep PF00132.24 KND88360.1 - 2.7e-08 33.2 4.9 0.0024 17.5 2.5 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KND88360.1 - 0.0034 17.1 0.7 0.11 12.3 0.2 3.1 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KND88360.1 - 0.0043 16.0 0.0 0.0058 15.6 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase UCH PF00443.29 KND88361.1 - 1.5e-45 155.8 0.0 3e-45 154.7 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND88361.1 - 7.6e-10 38.9 0.0 3.9e-08 33.2 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRP7 PF12923.7 KND88361.1 - 1.9 8.7 5.2 0.32 11.1 0.5 2.0 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SUIM_assoc PF16619.5 KND88361.1 - 5.9 7.0 9.0 22 5.2 9.0 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 UCR_14kD PF02271.16 KND88362.1 - 6.7e-42 141.5 1.2 8.6e-42 141.2 1.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Beta-lactamase PF00144.24 KND88362.1 - 0.033 13.4 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase Mito_carr PF00153.27 KND88364.1 - 5.6e-64 212.1 3.0 1.4e-21 76.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Dot_icm_IcmQ PF09475.10 KND88364.1 - 0.09 12.2 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) AhpC-TSA PF00578.21 KND88365.1 - 9.8e-26 90.1 0.0 1.6e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND88365.1 - 7e-15 55.0 0.0 9.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KND88365.1 - 0.0011 19.0 0.0 0.0097 16.0 0.0 2.2 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme CDC27 PF09507.10 KND88365.1 - 0.28 10.5 12.3 0.35 10.2 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SWIRM-assoc_2 PF16496.5 KND88365.1 - 1.9 7.3 7.2 2.5 6.9 7.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RNA_pol_Rpc4 PF05132.14 KND88365.1 - 2.9 8.3 11.1 5.4 7.4 11.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CI-B14_5a PF07347.12 KND88366.1 - 0.098 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Yae1_N PF09811.9 KND88367.1 - 1.1e-09 37.8 4.2 1.5e-09 37.4 4.2 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal tRNA-synt_1g PF09334.11 KND88368.1 - 3.1e-148 493.7 0.0 4.3e-148 493.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KND88368.1 - 4.4e-05 21.9 8.3 0.0033 15.8 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) CK1gamma_C PF12605.8 KND88368.1 - 0.12 13.5 2.4 0.23 12.7 2.4 1.3 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal DUF3807 PF12720.7 KND88368.1 - 3.3 8.0 8.2 6.3 7.0 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) zf-ribbon_3 PF13248.6 KND88368.1 - 3.7 7.1 6.6 17 5.0 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Acetyltransf_1 PF00583.25 KND88369.1 - 1.5e-10 41.3 0.0 2.4e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KND88369.1 - 1.1e-05 25.3 0.1 2.1e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KND88369.1 - 3.5e-05 23.7 0.1 5.3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND88369.1 - 4.1e-05 23.9 0.0 9.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND88369.1 - 0.021 14.9 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.6 KND88370.1 - 0.0012 19.5 0.3 0.0074 16.9 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Chorion_2 PF03964.15 KND88370.1 - 0.0042 17.9 5.2 0.0042 17.9 5.2 4.1 4 0 0 4 4 3 1 Chorion family 2 InvH PF04741.12 KND88370.1 - 0.0065 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 InvH outer membrane lipoprotein SUIM_assoc PF16619.5 KND88370.1 - 0.013 15.6 9.5 0.013 15.6 9.5 3.4 2 1 0 2 2 1 0 Unstructured region C-term to UIM in Ataxin3 Suf PF05843.14 KND88370.1 - 0.014 15.4 4.1 0.014 15.4 4.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 KND88370.1 - 0.053 13.1 22.8 0.12 12.0 22.8 1.5 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 KND88370.1 - 0.057 12.1 18.0 0.007 15.1 13.4 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF508 PF04370.12 KND88370.1 - 0.058 13.1 2.9 0.13 12.0 2.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF508) AAA_23 PF13476.6 KND88370.1 - 0.19 12.2 8.1 0.85 10.1 0.9 2.4 2 0 0 2 2 2 0 AAA domain Pex26 PF07163.12 KND88370.1 - 0.44 9.8 3.1 1.5 8.1 3.1 1.9 1 0 0 1 1 1 0 Pex26 protein V_ATPase_I PF01496.19 KND88370.1 - 2.9 5.7 9.5 4.8 5.0 2.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Peroxin-13_N PF04088.13 KND88370.1 - 7.4 6.8 7.4 24 5.2 0.0 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Presenilin PF01080.17 KND88370.1 - 9.4 4.9 16.3 0.15 10.8 4.1 2.3 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 KND88370.1 - 9.5 6.2 8.9 3.1 7.8 0.4 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FCH PF00611.23 KND88371.1 - 3.6e-24 84.8 0.0 1.3e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KND88371.1 - 1.1e-16 60.4 1.4 8.6e-09 35.1 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 KND88371.1 - 6e-15 54.9 5.2 9.4e-15 54.2 5.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 KND88371.1 - 3.8e-11 42.4 0.0 1.9e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 KND88371.1 - 0.0017 18.6 1.2 0.094 13.0 0.5 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.16 KND88371.1 - 0.0094 16.2 4.8 0.017 15.5 4.8 1.3 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 KND88371.1 - 0.018 14.7 0.8 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Allexi_40kDa PF05549.11 KND88371.1 - 0.13 11.8 1.3 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein FYVE PF01363.21 KND88371.1 - 0.23 11.6 3.6 0.5 10.5 3.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger Mer2 PF09074.10 KND88371.1 - 0.28 11.0 3.5 2.1 8.1 0.6 2.2 2 0 0 2 2 2 0 Mer2 zf-C2H2 PF00096.26 KND88372.1 - 8e-06 26.0 14.8 0.1 13.1 2.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type SHE3 PF17078.5 KND88372.1 - 0.017 14.8 5.9 0.026 14.3 5.9 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 HOOK PF05622.12 KND88372.1 - 0.025 12.7 4.5 0.044 11.9 4.5 1.3 1 0 0 1 1 1 0 HOOK protein Spc29 PF17082.5 KND88372.1 - 0.03 14.2 3.1 0.054 13.3 3.1 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 zf-C2H2_aberr PF17017.5 KND88372.1 - 0.031 14.4 0.4 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger Tho2 PF11262.8 KND88372.1 - 0.032 13.4 4.1 0.048 12.9 4.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AIP3 PF03915.13 KND88372.1 - 0.033 13.3 3.9 0.047 12.8 3.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 HAUS5 PF14817.6 KND88372.1 - 0.036 12.8 3.6 0.048 12.4 3.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 HIP1_clath_bdg PF16515.5 KND88372.1 - 0.04 14.5 7.7 0.083 13.5 7.7 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KND88372.1 - 0.072 13.5 3.3 0.16 12.4 3.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF3450 PF11932.8 KND88372.1 - 0.14 11.5 3.4 0.2 10.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-C2H2_4 PF13894.6 KND88372.1 - 0.19 12.7 12.1 5.8 8.0 1.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger ATG16 PF08614.11 KND88372.1 - 0.21 11.8 8.9 0.42 10.8 8.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 KND88372.1 - 0.34 8.8 2.1 0.45 8.4 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 KND88372.1 - 0.36 10.9 4.4 0.58 10.2 4.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 KND88372.1 - 0.51 10.2 2.7 1 9.2 2.7 1.5 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 KND88372.1 - 0.59 10.7 7.4 1 9.9 7.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1943 PF09172.11 KND88372.1 - 0.94 8.6 3.9 1.4 8.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF724 PF05266.14 KND88372.1 - 4.1 7.2 7.9 7.1 6.4 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF2408 PF10303.9 KND88373.1 - 4e-42 144.0 7.1 1e-25 90.8 0.0 5.3 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) Abi_C PF14355.6 KND88373.1 - 0.0082 16.2 0.3 0.3 11.2 0.2 2.9 3 0 0 3 3 3 1 Abortive infection C-terminus DUF489 PF04356.12 KND88373.1 - 0.013 15.5 1.8 0.23 11.4 1.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF489) HAP1_N PF04849.13 KND88373.1 - 0.024 13.9 3.0 0.035 13.3 3.0 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Spc7 PF08317.11 KND88373.1 - 0.2 10.5 3.6 0.45 9.3 3.6 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.11 KND88373.1 - 0.26 10.9 1.7 0.54 9.8 0.4 2.0 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.12 KND88373.1 - 0.85 8.1 2.6 1.1 7.6 2.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 KND88373.1 - 1.3 9.2 8.6 1.2 9.4 3.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc24 PF08286.11 KND88373.1 - 2.1 8.6 4.7 15 5.9 0.0 3.7 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 Laminin_II PF06009.12 KND88373.1 - 2.7 8.0 6.0 2.5 8.1 1.0 2.7 2 1 1 3 3 3 0 Laminin Domain II YCII PF03795.14 KND88374.1 - 2.8e-06 27.7 0.0 3.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain UBX PF00789.20 KND88375.1 - 9.3e-06 25.8 1.1 4e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 UBX domain UBA PF00627.31 KND88375.1 - 0.0041 17.0 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Exonuc_VII_L PF02601.15 KND88375.1 - 0.1 12.2 10.6 0.13 11.8 10.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOBP PF15279.6 KND88375.1 - 0.27 11.8 5.0 0.32 11.6 5.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4284 PF14112.6 KND88375.1 - 0.99 10.3 5.4 0.7 10.8 1.2 2.1 1 1 1 2 2 2 0 Immunity protein 22 GREB1 PF15782.5 KND88375.1 - 9.5 3.2 10.5 9.6 3.2 10.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ribosomal_60s PF00428.19 KND88376.1 - 8.6e-21 74.3 13.5 1e-16 61.3 5.1 2.1 2 0 0 2 2 2 2 60s Acidic ribosomal protein FA_desaturase PF00487.24 KND88377.1 - 1.6e-25 90.4 19.6 1.6e-25 90.4 19.6 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 KND88377.1 - 1.2e-18 66.2 0.6 2.5e-18 65.3 0.6 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KND88378.1 - 1.2e-22 79.8 0.0 7.8e-22 77.2 0.0 2.1 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KND88378.1 - 0.015 15.4 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 KND88378.1 - 0.063 13.5 0.2 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Tnp_DNA_bind PF14706.6 KND88378.1 - 0.063 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Transposase DNA-binding ICE2 PF08426.10 KND88379.1 - 3.7e-157 523.6 9.3 4.2e-157 523.4 9.3 1.0 1 0 0 1 1 1 1 ICE2 Aa_trans PF01490.18 KND88380.1 - 2.6e-22 79.1 28.4 3.3e-22 78.8 28.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.7 KND88381.1 - 7.8e-54 180.2 18.7 1.2e-12 48.2 0.4 5.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND88381.1 - 1.4e-31 104.9 3.8 0.0013 19.1 0.1 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KND88381.1 - 7.5e-31 105.8 0.6 1.3e-06 28.6 0.2 6.5 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND88381.1 - 3.7e-27 94.3 2.0 1.3e-06 28.9 0.0 6.5 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 KND88381.1 - 2.6e-20 71.9 10.8 0.00063 20.1 0.3 8.7 8 1 0 8 8 8 6 Ankyrin repeat adh_short PF00106.25 KND88382.1 - 1.4e-21 76.8 0.0 6.7e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND88382.1 - 1.7e-12 47.4 0.0 3.9e-12 46.2 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND88382.1 - 1e-05 25.5 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND88382.1 - 0.00037 20.0 0.0 0.00071 19.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND88382.1 - 0.0026 17.2 0.0 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KND88382.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1508 PF07411.12 KND88382.1 - 0.18 11.7 1.6 0.25 11.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) Glyco_hydro_18 PF00704.28 KND88383.1 - 5.3e-23 82.2 2.8 1e-22 81.3 2.8 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 KND88383.1 - 1e-08 35.0 16.0 1e-08 35.0 16.0 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain COPIIcoated_ERV PF07970.12 KND88384.1 - 7.3e-35 120.8 0.0 1.1e-34 120.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KND88384.1 - 5.4e-23 81.2 0.0 9e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glyco_hydro_76 PF03663.14 KND88385.1 - 1.5e-141 472.2 12.2 1.8e-141 471.9 12.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND88385.1 - 0.1 11.6 7.9 1.5 7.8 0.4 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 HET PF06985.11 KND88387.1 - 2.7e-21 76.5 0.0 5.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 KND88388.1 - 1.3e-09 38.1 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND88388.1 - 7.9e-07 28.9 0.1 6.1e-06 26.1 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KND88388.1 - 0.00013 23.1 0.0 0.00025 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4567 PF15131.6 KND88388.1 - 0.022 14.8 0.2 0.052 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) AA_permease_2 PF13520.6 KND88389.1 - 4.7e-48 164.1 50.8 5.5e-48 163.8 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND88389.1 - 3.6e-24 85.2 41.0 5.3e-24 84.7 41.0 1.2 1 0 0 1 1 1 1 Amino acid permease Translin PF01997.16 KND88391.1 - 4.1e-49 167.4 0.0 4.7e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF5631 PF18645.1 KND88391.1 - 0.024 15.0 0.3 0.42 11.0 0.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5631) Ribosomal_S13_N PF08069.12 KND88391.1 - 0.031 14.3 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain Pro-kuma_activ PF09286.11 KND88392.1 - 8.2e-22 78.0 0.0 2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KND88392.1 - 1.2e-07 31.3 0.1 1.9e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 KND88393.1 - 6.8e-22 77.9 25.9 6.8e-22 77.9 25.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4690 PF15756.5 KND88393.1 - 0.039 14.5 0.6 0.13 12.8 0.6 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Trp_oprn_chp PF09534.10 KND88393.1 - 5.2 6.8 8.4 0.12 12.1 0.7 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1 PF07690.16 KND88394.1 - 0.00021 20.3 0.3 0.00025 20.1 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MNSV_P7B PF06692.11 KND88394.1 - 0.0029 17.6 0.4 0.0057 16.6 0.4 1.4 1 0 0 1 1 1 1 Melon necrotic spot virus P7B protein Fungal_trans PF04082.18 KND88395.1 - 1.5e-18 66.8 0.0 2.6e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 KND88396.1 - 2.8e-46 157.7 0.1 4.2e-46 157.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KND88396.1 - 1.6e-05 24.7 4.6 7.9e-05 22.5 1.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND88396.1 - 0.00055 19.6 1.2 0.0013 18.5 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND88396.1 - 0.0065 16.7 0.6 0.013 15.7 0.3 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND88396.1 - 0.039 14.6 1.1 0.19 12.4 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND88396.1 - 0.077 13.2 0.1 0.24 11.6 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND88396.1 - 0.089 13.7 0.4 0.42 11.5 0.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND88396.1 - 0.1 12.9 1.2 0.3 11.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 KND88398.1 - 2.3e-28 99.4 0.0 2.2e-25 89.6 0.0 2.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KND88398.1 - 1.1e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain MBR1 PF17058.5 KND88399.1 - 0.83 9.9 5.5 15 5.8 0.2 3.2 2 1 1 3 3 3 0 Mitochondrial biogenesis regulation protein 1 DAO PF01266.24 KND88400.1 - 1e-29 104.3 0.0 1.2e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KND88400.1 - 1.6e-06 27.5 0.0 0.00031 19.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KND88400.1 - 1.9e-06 27.2 0.1 0.00098 18.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KND88400.1 - 2.5e-05 23.7 0.0 0.063 12.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND88400.1 - 0.00012 22.1 0.1 0.067 13.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KND88400.1 - 0.00093 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND88400.1 - 0.0037 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND88400.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KND88400.1 - 0.014 14.6 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND88400.1 - 0.03 13.4 0.1 3 6.8 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KND88400.1 - 0.033 12.9 0.0 4.8 5.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 KND88400.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 KND88400.1 - 0.15 11.5 0.0 0.83 9.1 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 KND88400.1 - 0.19 12.0 0.0 0.55 10.5 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain MRP-L20 PF12824.7 KND88401.1 - 3.2e-50 170.5 1.4 4e-50 170.2 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 KND88401.1 - 0.0013 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Neugrin zf-C4H2 PF10146.9 KND88402.1 - 0.092 13.0 1.9 0.12 12.6 1.9 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein HypA PF01155.19 KND88402.1 - 0.098 12.7 1.2 0.16 12.0 1.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Not3 PF04065.15 KND88403.1 - 2.4e-89 298.7 22.9 3.6e-89 298.2 22.9 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KND88403.1 - 1e-42 145.3 8.0 1e-42 145.3 8.0 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KND88403.1 - 0.011 16.1 2.1 0.011 16.1 2.1 2.4 3 0 0 3 3 3 0 Syntaxin-like protein Cep57_MT_bd PF06657.13 KND88403.1 - 0.035 14.5 8.1 0.75 10.3 1.4 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.9 KND88403.1 - 0.058 13.3 4.8 0.13 12.1 4.8 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 KND88403.1 - 0.069 13.2 4.2 0.074 13.1 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) CorA PF01544.18 KND88403.1 - 3.6 6.8 5.3 1 8.6 1.2 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ER_lumen_recept PF00810.18 KND88404.1 - 2.1e-40 139.0 9.7 3.2e-40 138.3 9.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KND88404.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.7 4 0 0 4 4 4 0 PQ loop repeat CS PF04969.16 KND88405.1 - 5.5e-16 59.4 0.0 1.3e-15 58.1 0.0 1.7 1 0 0 1 1 1 1 CS domain LicD PF04991.13 KND88406.1 - 2.5e-17 63.8 8.9 9.8e-11 42.2 0.3 3.0 2 1 1 3 3 3 2 LicD family DUF2518 PF10726.9 KND88406.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of function (DUF2518) zf-C3HC4_5 PF17121.5 KND88407.1 - 2.9e-30 103.9 9.1 4.6e-30 103.3 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MAT1 PF06391.13 KND88407.1 - 3.7e-30 105.3 4.5 5e-30 104.9 4.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 KND88407.1 - 4.2e-05 23.3 6.5 0.00011 22.0 6.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND88407.1 - 0.0011 18.7 8.8 0.0023 17.7 8.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND88407.1 - 0.0031 17.8 6.7 0.0062 16.8 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain DUF3797 PF12677.7 KND88407.1 - 0.019 14.9 4.4 0.03 14.2 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-C3HC4_2 PF13923.6 KND88407.1 - 0.019 14.8 8.7 0.14 12.0 8.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRP-S26 PF14943.6 KND88407.1 - 0.039 13.9 9.3 0.061 13.2 9.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_10 PF16685.5 KND88407.1 - 0.042 14.0 2.8 0.076 13.2 2.8 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 FAM199X PF15814.5 KND88407.1 - 0.068 12.2 3.2 0.096 11.7 3.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X zf-piccolo PF05715.13 KND88407.1 - 0.097 12.8 2.6 0.19 11.9 2.6 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_4 PF14570.6 KND88407.1 - 0.13 12.0 11.8 1.7 8.5 12.1 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1359 PF07097.11 KND88407.1 - 0.18 12.1 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1359) zf-RING_5 PF14634.6 KND88407.1 - 0.2 11.6 11.4 1.4 8.9 11.5 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KND88407.1 - 0.29 11.3 2.6 0.64 10.2 2.6 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KND88407.1 - 1 9.4 5.8 2 8.5 5.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 KND88407.1 - 3.6 7.8 9.0 19 5.4 9.0 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 KND88407.1 - 6 6.8 8.4 13 5.7 2.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 tRNA-synt_2 PF00152.20 KND88409.1 - 3.1e-64 217.0 0.0 5.3e-63 213.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.25 KND88410.1 - 1.3e-69 234.5 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88410.1 - 1.1e-31 110.0 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND88410.1 - 0.01 14.8 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND88410.1 - 0.051 12.9 0.1 0.097 12.0 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88410.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family LMWPc PF01451.21 KND88411.1 - 1.9e-25 89.9 0.0 2.2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Band_7 PF01145.25 KND88412.1 - 3.6e-23 82.5 7.5 3.6e-23 82.5 7.5 1.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KND88412.1 - 0.0039 16.3 6.4 0.0059 15.7 6.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 KND88412.1 - 0.062 13.0 0.1 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 SPFH domain-Band 7 family UcrQ PF02939.16 KND88413.1 - 1.3e-36 124.4 0.3 1.6e-36 124.1 0.3 1.1 1 0 0 1 1 1 1 UcrQ family DUF676 PF05057.14 KND88414.1 - 8.4e-51 172.6 0.0 1.2e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND88414.1 - 3.5e-05 23.7 0.0 0.00039 20.2 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KND88414.1 - 5.1e-05 23.2 0.0 7.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KND88414.1 - 0.00035 21.3 0.0 0.006 17.2 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family NIF PF03031.18 KND88416.1 - 1.4e-51 174.3 0.0 2.3e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 KND88417.1 - 1.6e-50 171.9 0.2 5.4e-50 170.2 0.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 KND88417.1 - 0.0094 15.9 0.2 0.043 13.7 0.2 2.0 1 1 0 1 1 1 1 DeoR C terminal sensor domain Ribosomal_L7Ae PF01248.26 KND88418.1 - 1.5e-21 75.9 1.4 3.2e-21 74.9 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ComGG PF14173.6 KND88418.1 - 0.013 15.9 0.0 4 7.9 0.0 2.7 3 0 0 3 3 3 0 ComG operon protein 7 RNase_P_pop3 PF08228.11 KND88418.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 RRM_Rrp7 PF17799.1 KND88418.1 - 0.14 12.0 1.1 0.18 11.6 0.3 1.6 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FAM60A PF15396.6 KND88418.1 - 3.1 7.7 9.7 1 9.4 6.4 1.7 2 0 0 2 2 2 0 Protein Family FAM60A DUF1761 PF08570.10 KND88419.1 - 6.3e-27 94.3 2.6 7.8e-27 94.0 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) zf-CCHC PF00098.23 KND88420.1 - 2.9e-38 128.3 45.2 5.4e-09 35.7 4.3 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 KND88420.1 - 7.1e-09 35.3 27.1 0.0045 16.7 0.7 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 KND88420.1 - 1.1e-07 31.6 30.5 0.12 12.4 0.5 5.1 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 KND88420.1 - 1.9e-07 30.8 32.3 0.024 14.4 2.0 5.2 3 1 2 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 KND88420.1 - 0.00029 20.5 22.5 0.48 10.2 0.2 4.3 3 1 1 4 4 4 4 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 KND88420.1 - 6 7.1 10.5 16 5.7 0.1 3.9 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Acyl-CoA_dh_1 PF00441.24 KND88421.1 - 1.5e-29 103.1 0.2 2.6e-29 102.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KND88421.1 - 3.9e-19 68.6 0.0 9.8e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KND88421.1 - 2.4e-17 62.9 0.2 4.1e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KND88421.1 - 2.9e-09 37.6 0.1 6e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KND88421.1 - 8.1e-05 22.9 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 KND88422.1 - 4.2e-44 151.1 0.0 6.8e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KND88424.1 - 3.1e-17 62.5 0.1 4.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88424.1 - 8.2e-08 32.2 9.0 1.7e-07 31.2 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FGGY_C PF02782.16 KND88425.1 - 7.4e-71 238.0 0.9 1.2e-70 237.3 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KND88425.1 - 4e-67 226.3 0.0 5.4e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 KND88426.1 - 9.6e-48 162.8 1.0 1.3e-47 162.4 1.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein APT PF03440.14 KND88426.1 - 0.03 14.3 0.2 0.21 11.6 0.3 2.1 2 0 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain G3P_acyltransf PF02660.15 KND88426.1 - 0.39 10.8 5.9 0.66 10.0 5.8 1.4 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase DAO PF01266.24 KND88427.1 - 6.7e-52 177.2 1.7 6.7e-52 177.2 1.7 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 KND88427.1 - 6.4e-39 132.7 0.0 2.7e-38 130.7 0.0 2.1 3 0 0 3 3 3 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KND88427.1 - 4.9e-08 32.5 3.7 0.00075 18.7 1.1 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KND88427.1 - 0.00021 20.8 2.1 0.00024 20.6 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND88427.1 - 0.0014 18.0 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND88427.1 - 0.0074 16.5 1.1 0.025 14.8 0.7 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 KND88427.1 - 0.016 15.1 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KND88427.1 - 0.03 13.6 0.6 0.077 12.2 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KND88427.1 - 0.051 12.3 0.4 0.077 11.7 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KND88427.1 - 0.058 12.6 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KND88427.1 - 0.074 12.1 0.2 0.21 10.6 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KND88427.1 - 0.082 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND88427.1 - 0.12 12.9 1.0 0.31 11.6 0.2 2.1 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1b PF00579.25 KND88428.1 - 1.7e-35 122.8 0.0 2.9e-23 82.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (W and Y) SAE2 PF08573.10 KND88429.1 - 1.7e-37 128.9 0.1 1.7e-37 128.9 0.1 3.0 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Pkinase PF00069.25 KND88430.1 - 5.1e-72 242.4 0.0 7.3e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88430.1 - 2.5e-51 174.5 0.0 3.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND88430.1 - 2.3e-05 23.4 0.0 4.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KND88430.1 - 0.0054 16.1 0.0 0.1 11.9 0.1 2.2 2 0 0 2 2 2 1 Kinase-like LAT PF15234.6 KND88430.1 - 0.077 12.7 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Linker for activation of T-cells RTTN_N PF14726.6 KND88431.1 - 0.22 12.4 4.6 0.51 11.2 0.7 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Mur_ligase_M PF08245.12 KND88432.1 - 5e-08 33.2 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 KND88432.1 - 0.049 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain T7SS_ESX_EspC PF10824.8 KND88432.1 - 0.061 13.8 1.0 0.14 12.6 0.2 2.0 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Kri1 PF05178.12 KND88433.1 - 0.07 13.7 0.2 0.15 12.6 0.2 1.5 1 0 0 1 1 1 0 KRI1-like family Ank_2 PF12796.7 KND88435.1 - 1.3e-11 45.0 0.1 1.5e-05 25.5 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND88435.1 - 2.8e-09 37.3 0.3 0.0064 17.0 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KND88435.1 - 1e-08 35.2 0.4 0.00065 20.0 0.1 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KND88435.1 - 3.3e-08 33.1 0.1 0.043 14.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KND88435.1 - 5.7e-08 32.9 1.8 5.4e-05 23.4 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KND88435.1 - 6.2e-07 29.2 0.1 5.8e-06 26.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain SnAC PF14619.6 KND88435.1 - 0.092 13.4 2.3 0.13 12.9 0.1 2.4 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex Ndr PF03096.14 KND88437.1 - 0.0014 17.4 0.0 0.0022 16.8 0.0 1.2 1 0 0 1 1 1 1 Ndr family FlgN PF05130.12 KND88437.1 - 0.093 13.2 0.3 0.16 12.5 0.3 1.3 1 0 0 1 1 1 0 FlgN protein zf-CCCH PF00642.24 KND88437.1 - 1.3 9.0 10.4 0.094 12.7 4.3 2.5 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Actin PF00022.19 KND88438.1 - 8.8e-125 416.5 0.0 3.5e-124 414.5 0.0 1.7 1 1 0 1 1 1 1 Actin Clr5 PF14420.6 KND88439.1 - 1.1e-06 28.7 1.0 3.8e-06 27.0 0.5 2.3 2 0 0 2 2 2 1 Clr5 domain DUF892 PF05974.12 KND88439.1 - 0.028 14.4 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3435 PF11917.8 KND88440.1 - 2.4e-05 23.5 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) APH PF01636.23 KND88441.1 - 1.9e-09 37.8 0.0 1.1e-08 35.3 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88441.1 - 0.016 14.8 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase PNP_UDP_1 PF01048.20 KND88442.1 - 2.8e-07 30.0 0.4 4.3e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 KND88443.1 - 3.4e-31 107.7 1.0 3.9e-14 53.0 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND88443.1 - 4.8e-27 94.0 0.2 1.8e-11 44.3 0.0 6.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88443.1 - 1.9e-21 73.9 0.2 0.00029 21.1 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KND88443.1 - 2.3e-18 66.0 1.4 7e-07 29.4 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KND88443.1 - 8.2e-16 57.7 0.5 0.0082 16.5 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat NACHT PF05729.12 KND88443.1 - 0.0021 18.0 0.1 0.014 15.4 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND88443.1 - 0.0085 16.5 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND88443.1 - 0.02 15.1 0.0 0.083 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain EF-hand_1 PF00036.32 KND88445.1 - 6.8e-42 137.9 10.7 8.4e-10 37.5 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KND88445.1 - 4.3e-36 123.2 5.8 4.3e-19 68.7 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KND88445.1 - 4.5e-34 116.1 11.9 2.6e-15 56.0 0.6 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KND88445.1 - 5.5e-31 103.8 7.1 2e-09 36.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KND88445.1 - 8.8e-26 88.2 10.6 2.8e-06 26.6 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KND88445.1 - 3.5e-16 59.3 0.3 5.2e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KND88445.1 - 4.5e-09 36.2 1.8 0.00073 19.5 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KND88445.1 - 8.1e-09 35.8 0.4 0.0024 18.2 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KND88445.1 - 2.5e-06 27.4 0.0 0.0084 16.1 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KND88445.1 - 7.7e-06 25.9 1.6 2.6e-05 24.2 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KND88445.1 - 0.00013 22.7 0.1 0.0061 17.4 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 KND88445.1 - 0.00063 20.1 0.2 0.69 10.3 0.1 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 KND88445.1 - 0.00066 19.6 1.0 0.37 10.7 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 KND88445.1 - 0.00094 19.2 0.1 0.88 9.5 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 KND88445.1 - 0.0083 16.3 6.6 0.46 10.7 0.9 2.8 2 2 1 3 3 3 2 Dockerin type I domain SurA_N_2 PF13623.6 KND88445.1 - 0.012 15.4 0.6 0.64 9.9 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 KND88445.1 - 0.018 15.4 0.6 7.4 7.0 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain DUF5580 PF17743.1 KND88445.1 - 0.051 12.1 0.0 0.052 12.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) MotA_activ PF09114.10 KND88445.1 - 0.07 13.3 0.1 1.1 9.5 0.0 2.3 2 1 0 2 2 2 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 KND88445.1 - 0.072 13.6 0.0 9.2 6.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Poly_export PF02563.16 KND88445.1 - 0.09 13.0 0.0 0.69 10.2 0.0 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF5132 PF17195.4 KND88445.1 - 0.18 12.0 0.5 22 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Adaptin_N PF01602.20 KND88446.1 - 5.1e-131 437.8 0.9 8.2e-66 222.6 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KND88446.1 - 7.9e-24 84.1 0.1 2.2e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KND88446.1 - 1.1e-06 28.8 7.2 0.00039 20.5 0.0 4.5 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND88446.1 - 0.00012 22.4 2.0 0.15 12.4 0.0 3.7 3 1 0 3 3 3 2 HEAT repeats DUF3730 PF12530.8 KND88446.1 - 0.00059 19.5 0.1 0.0039 16.8 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 KND88446.1 - 0.0019 18.3 0.9 6.3 7.3 0.1 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KND88446.1 - 0.12 12.9 1.7 48 4.6 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat DUF4954 PF16314.5 KND88446.1 - 0.15 10.2 1.0 1 7.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4954) SNARE PF05739.19 KND88448.1 - 1.7e-16 60.0 0.3 4.2e-16 58.7 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KND88448.1 - 0.00013 21.7 12.7 0.0031 17.2 1.0 2.2 2 0 0 2 2 2 2 Syntaxin DASH_Dad4 PF08650.10 KND88448.1 - 0.002 18.0 0.3 0.087 12.8 0.0 2.5 2 0 0 2 2 2 1 DASH complex subunit Dad4 Phage_cap_P2 PF05125.12 KND88448.1 - 0.0031 16.5 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Phage major capsid protein, P2 family Uds1 PF15456.6 KND88448.1 - 0.012 15.8 2.2 0.019 15.1 0.6 2.1 1 1 1 2 2 2 0 Up-regulated During Septation Cauli_DNA-bind PF03310.13 KND88448.1 - 0.043 13.9 3.7 0.046 13.8 0.9 2.1 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein MCPsignal PF00015.21 KND88448.1 - 0.081 12.7 8.3 0.12 12.2 0.9 2.5 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AAA_24 PF13479.6 KND88448.1 - 0.086 12.5 0.4 0.44 10.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain GCP_C_terminal PF04130.13 KND88448.1 - 0.095 12.1 0.7 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal DASH_Spc34 PF08657.10 KND88448.1 - 0.24 11.1 5.2 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 SlyX PF04102.12 KND88448.1 - 4.3 8.0 9.4 1.2 9.8 0.3 3.7 2 2 2 4 4 4 0 SlyX Clathrin_lg_ch PF01086.17 KND88449.1 - 4.4e-73 246.1 2.5 5e-73 246.0 2.5 1.0 1 0 0 1 1 1 1 Clathrin light chain TipAS PF07739.13 KND88449.1 - 0.17 12.5 5.3 0.31 11.6 5.3 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain COX7a PF02238.15 KND88450.1 - 3.3e-21 75.4 1.9 4.7e-21 74.9 1.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII ABC_membrane PF00664.23 KND88451.1 - 1.5e-50 172.4 10.1 2e-50 172.0 10.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND88451.1 - 1.1e-33 116.7 0.0 2.9e-33 115.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND88451.1 - 5.6e-05 22.7 0.0 0.0015 18.0 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND88451.1 - 0.00074 19.8 0.1 0.0059 16.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND88451.1 - 0.006 17.0 0.1 0.021 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KND88451.1 - 0.034 14.6 0.6 0.39 11.1 0.1 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KND88451.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KND88451.1 - 0.049 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KND88451.1 - 0.05 13.3 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KND88451.1 - 0.07 12.9 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 KND88451.1 - 0.07 13.4 1.5 1.1 9.5 1.5 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KND88451.1 - 0.089 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DEAD PF00270.29 KND88451.1 - 0.19 11.5 0.1 1.2 8.8 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase CTD_bind PF04818.13 KND88452.1 - 1.3e-16 61.2 0.2 4e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PhoU PF01895.19 KND88452.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoU domain CTK3 PF12243.8 KND88452.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Pkinase PF00069.25 KND88454.1 - 0.0005 19.5 0.0 0.00055 19.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND88454.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family p450 PF00067.22 KND88455.1 - 9.1e-42 143.4 0.0 1.2e-41 143.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Adeno_VII PF03228.14 KND88456.1 - 0.032 14.8 0.0 0.056 14.1 0.0 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII PS_Dcarbxylase PF02666.15 KND88457.1 - 1.6e-78 262.8 0.0 5.6e-78 261.1 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Nitroreductase PF00881.24 KND88458.1 - 8.4e-15 55.2 0.1 1e-14 55.0 0.1 1.0 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_1 PF00667.20 KND88459.1 - 1.5e-42 145.7 0.0 2.2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KND88459.1 - 1.7e-09 38.3 0.0 7.2e-09 36.3 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain HNH_2 PF13391.6 KND88460.1 - 2.1e-12 47.0 1.1 5.7e-12 45.6 0.5 2.1 2 0 0 2 2 2 1 HNH endonuclease AAA PF00004.29 KND88461.1 - 1.3e-11 45.1 0.0 2.7e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND88461.1 - 6.7e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KND88461.1 - 1.9e-05 24.7 0.0 7.7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KND88461.1 - 2e-05 24.9 0.0 5.8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KND88461.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND88461.1 - 0.0003 21.0 0.6 0.0013 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KND88461.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND88461.1 - 0.0037 17.7 0.3 0.021 15.2 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 KND88461.1 - 0.016 15.7 0.0 0.046 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KND88461.1 - 0.019 14.9 0.3 0.08 12.9 0.1 2.1 2 0 0 2 2 2 0 NTPase cobW PF02492.19 KND88461.1 - 0.041 13.5 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 KND88461.1 - 0.041 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 KND88461.1 - 0.049 13.4 1.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KND88461.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND88461.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain BRO1 PF03097.18 KND88462.1 - 4.4e-129 430.7 1.2 4.4e-129 430.7 1.2 1.8 2 0 0 2 2 2 1 BRO1-like domain FMN_dh PF01070.18 KND88462.1 - 1.1e-115 386.4 1.6 2e-115 385.5 1.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ALIX_LYPXL_bnd PF13949.6 KND88462.1 - 1.1e-78 264.5 18.1 1.1e-78 264.5 18.1 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Cyt-b5 PF00173.28 KND88462.1 - 7.3e-15 54.9 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KND88462.1 - 0.002 17.4 0.0 0.0049 16.0 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KND88462.1 - 0.0063 15.6 0.1 0.017 14.1 0.1 1.7 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KND88462.1 - 0.027 13.9 0.3 0.061 12.7 0.3 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase FlaC_arch PF05377.11 KND88462.1 - 0.34 11.3 1.3 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GLTP PF08718.11 KND88463.1 - 6.7e-44 149.8 0.0 1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Methyltransf_2 PF00891.18 KND88464.1 - 7.1e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain GAPES3 PF17154.4 KND88464.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Methyltransf_19 PF04672.12 KND88464.1 - 0.065 12.7 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase PLDc PF00614.22 KND88465.1 - 1e-14 54.0 1.5 4.5e-07 29.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KND88465.1 - 4.9e-14 52.4 1.3 8.7e-06 25.7 0.0 4.5 3 1 1 4 4 4 4 PLD-like domain Methyltransf_23 PF13489.6 KND88469.1 - 1.7e-19 70.2 0.0 4.7e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND88469.1 - 1.4e-11 45.0 0.0 3.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND88469.1 - 1.1e-09 38.8 0.0 2.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND88469.1 - 3.6e-09 36.6 0.0 7.6e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND88469.1 - 3.9e-07 30.7 0.0 2.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KND88469.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KND88469.1 - 0.00077 19.1 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KND88469.1 - 0.0018 17.8 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KND88469.1 - 0.014 14.7 0.0 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Ubie_methyltran PF01209.18 KND88469.1 - 0.016 14.6 0.0 0.21 10.9 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KND88469.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase FtsJ PF01728.19 KND88469.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 KND88469.1 - 0.25 10.6 0.1 0.42 9.9 0.1 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Pkinase PF00069.25 KND88470.1 - 2.1e-27 96.2 0.0 4.7e-27 95.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88470.1 - 6.4e-09 35.5 0.0 2.9e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Septin PF00735.18 KND88471.1 - 8.9e-119 395.9 0.2 8.9e-119 395.9 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KND88471.1 - 3e-08 33.7 1.1 5.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND88471.1 - 6.4e-06 25.8 1.4 0.00033 20.2 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KND88471.1 - 5.6e-05 23.7 1.1 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 KND88471.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KND88471.1 - 0.0018 17.6 2.0 0.0027 17.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 KND88471.1 - 0.0022 18.4 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND88471.1 - 0.0034 17.3 1.0 0.0034 17.3 1.0 3.3 3 1 0 3 3 2 1 RsgA GTPase Ras PF00071.22 KND88471.1 - 0.011 15.3 0.9 0.05 13.2 0.0 2.4 3 0 0 3 3 2 0 Ras family AAA_29 PF13555.6 KND88471.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KND88471.1 - 0.028 14.7 1.6 0.038 14.3 0.1 2.2 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KND88471.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KND88471.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND88471.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KND88471.1 - 0.13 12.7 0.5 0.68 10.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KND88471.1 - 0.14 11.9 2.2 6.8 6.4 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 KND88471.1 - 0.17 11.9 8.1 0.98 9.5 0.0 3.4 3 1 0 3 3 2 0 Dynamin family AAA_5 PF07728.14 KND88471.1 - 0.23 11.5 1.2 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Caldesmon PF02029.15 KND88471.1 - 0.54 8.9 17.4 0.84 8.3 17.4 1.3 1 0 0 1 1 1 0 Caldesmon Exonuc_VII_L PF02601.15 KND88471.1 - 0.65 9.5 7.8 1 8.8 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 KND88471.1 - 1.5 8.8 5.3 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AP1AR PF15745.5 KND88471.1 - 1.6 8.3 10.1 3.4 7.2 10.1 1.5 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Strep_SA_rep PF06696.11 KND88471.1 - 8.3 6.5 6.9 2.8 8.1 3.5 1.9 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Ferrochelatase PF00762.19 KND88472.1 - 7.2e-97 324.3 0.0 8.4e-97 324.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 KND88472.1 - 0.063 12.9 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) Ku PF02735.16 KND88473.1 - 8.8e-47 159.4 0.0 1.6e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KND88473.1 - 1.6e-35 122.9 0.0 2.5e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KND88473.1 - 1.4e-25 89.8 1.8 1.4e-25 89.8 1.8 2.8 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Zn_clus PF00172.18 KND88473.1 - 3.1e-07 30.4 11.4 3.5e-07 30.2 9.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KND88474.1 - 1.9e-31 109.3 37.5 1.9e-31 109.3 37.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Androgen_recep PF02166.16 KND88474.1 - 0.77 8.5 6.4 1.1 8.0 6.4 1.1 1 0 0 1 1 1 0 Androgen receptor Spt20 PF12090.8 KND88474.1 - 1.1 8.8 5.6 1.5 8.3 5.6 1.1 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 KND88474.1 - 2.5 6.3 5.5 3.4 5.8 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LprI PF07007.12 KND88476.1 - 0.034 14.8 0.4 2 9.1 0.0 2.4 1 1 1 2 2 2 0 Lysozyme inhibitor LprI Spc24 PF08286.11 KND88477.1 - 2.9e-36 123.9 0.1 2.3e-34 117.8 0.0 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 CbiQ PF02361.16 KND88477.1 - 0.21 11.2 0.5 0.31 10.6 0.5 1.2 1 0 0 1 1 1 0 Cobalt transport protein FUSC PF04632.12 KND88477.1 - 0.42 9.1 10.2 0.51 8.8 10.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fis1_TPR_C PF14853.6 KND88478.1 - 1.1e-24 86.2 1.6 1.8e-24 85.6 1.6 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KND88478.1 - 2.3e-08 33.6 0.9 3e-08 33.2 0.1 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KND88478.1 - 0.0067 16.4 1.0 0.011 15.8 1.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat NCBP3 PF10309.9 KND88479.1 - 1.6e-19 69.5 0.0 3.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 SRP_TPR_like PF17004.5 KND88480.1 - 4.9e-22 78.1 2.7 1.5e-20 73.4 0.4 3.0 3 0 0 3 3 3 1 Putative TPR-like repeat SRP72 PF08492.12 KND88480.1 - 1.4e-13 51.1 7.7 1.4e-13 51.1 7.7 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 KND88480.1 - 9.6e-05 22.2 23.2 0.19 11.9 0.0 7.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND88480.1 - 0.00033 21.1 33.6 0.13 12.7 0.1 7.6 5 3 1 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND88480.1 - 0.002 18.3 11.9 0.024 14.8 0.7 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KND88480.1 - 0.016 16.0 33.3 2.5 9.2 0.1 8.4 6 2 3 9 9 7 0 Tetratricopeptide repeat SPO22 PF08631.10 KND88480.1 - 0.039 13.4 2.0 0.66 9.4 0.0 2.6 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KND88480.1 - 0.04 14.2 16.8 5.6 7.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND88480.1 - 0.067 13.0 12.5 7.2 6.6 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 KND88480.1 - 0.2 11.8 2.3 7.1 6.8 0.6 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 KND88480.1 - 0.65 10.5 4.3 49 4.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND88480.1 - 1.2 9.1 13.3 3 7.8 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND88480.1 - 2 9.2 15.7 1.5 9.6 0.7 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND88480.1 - 6 7.3 12.7 37 4.9 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KND88480.1 - 6.5 7.5 37.5 3.1 8.5 0.0 7.9 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND88480.1 - 9 7.3 21.6 6.7 7.7 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat APH PF01636.23 KND88481.1 - 4.1e-13 49.8 0.0 1e-12 48.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88481.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Trypan_PARP PF05887.11 KND88481.1 - 0.056 13.4 3.4 0.095 12.7 3.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-BED PF02892.15 KND88482.1 - 0.00074 19.5 0.4 0.00074 19.5 0.4 1.8 2 0 0 2 2 2 1 BED zinc finger GON PF08685.11 KND88482.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 GON domain zf-C2H2_12 PF18658.1 KND88482.1 - 0.055 13.0 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger C2H2-type Fungal_trans PF04082.18 KND88483.1 - 1.6e-25 89.7 0.3 2.2e-25 89.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyridox_oxase_2 PF12766.7 KND88484.1 - 7.7e-20 71.4 0.0 1.1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ig_J_chain PF15097.6 KND88484.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin J chain LRR_9 PF14580.6 KND88487.1 - 1.4e-53 181.0 0.0 2.3e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 KND88487.1 - 9.7e-10 38.6 3.3 2.1e-05 24.8 0.2 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND88487.1 - 6.4e-09 35.4 0.2 3e-08 33.3 0.2 2.2 3 0 0 3 3 3 1 Leucine rich repeat DUF4349 PF14257.6 KND88487.1 - 0.0064 16.0 1.8 0.013 15.0 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KND88487.1 - 0.078 13.1 0.6 63 4.0 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 KND88487.1 - 0.15 12.7 0.1 1.2e+02 3.8 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat CBFD_NFYB_HMF PF00808.23 KND88488.1 - 1.2e-11 44.7 1.6 1.9e-11 44.1 1.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pol_alpha_B_N PF08418.10 KND88488.1 - 0.0026 17.8 0.9 0.003 17.6 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal TAFII28 PF04719.14 KND88488.1 - 0.033 14.3 0.2 0.055 13.6 0.2 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Histone PF00125.24 KND88488.1 - 0.083 13.3 0.3 0.083 13.3 0.3 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF1589 PF07628.11 KND88489.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) Cofac_haem_bdg PF04187.13 KND88489.1 - 0.18 11.7 1.5 0.38 10.7 1.5 1.5 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF5595 PF18077.1 KND88489.1 - 0.27 11.3 0.7 0.85 9.7 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Pkinase PF00069.25 KND88490.1 - 2.7e-21 76.1 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KND88490.1 - 6e-09 36.4 17.1 1.9e-05 25.3 0.2 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 KND88490.1 - 5.5e-07 29.3 3.3 0.31 11.4 0.1 6.6 6 0 0 6 6 6 1 HEAT repeat Pkinase_Tyr PF07714.17 KND88490.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KND88490.1 - 0.0017 18.7 1.7 0.29 11.5 0.0 4.0 3 1 1 4 4 4 1 HEAT repeats Kinase-like PF14531.6 KND88490.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KND88490.1 - 0.032 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_N PF01602.20 KND88490.1 - 0.065 11.8 0.2 0.46 9.0 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region RTP1_C1 PF10363.9 KND88490.1 - 0.085 13.0 0.8 6.4 7.0 0.1 2.8 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Abhydrolase_1 PF00561.20 KND88491.1 - 3.1e-26 92.6 0.0 3.5e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND88491.1 - 2e-15 58.0 0.1 2.9e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND88491.1 - 1e-11 44.6 0.1 2e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KND88491.1 - 3.8e-06 26.8 0.1 0.019 14.7 0.1 2.2 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 KND88491.1 - 5.4e-05 23.4 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KND88491.1 - 0.0004 20.1 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF3530 PF12048.8 KND88491.1 - 0.0048 16.4 0.1 0.0091 15.5 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3530) Palm_thioest PF02089.15 KND88491.1 - 0.07 13.0 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 KND88491.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Acyl_transf_1 PF00698.21 KND88491.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Chlorophyllase2 PF12740.7 KND88491.1 - 0.14 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 KND88491.1 - 0.14 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.16 KND88491.1 - 0.22 11.3 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ribosomal_S3Ae PF01015.18 KND88492.1 - 2e-89 298.6 2.0 2.4e-89 298.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 KND88492.1 - 0.018 15.6 0.1 0.063 13.8 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor SUI1 Erythro-docking PF09277.11 KND88492.1 - 0.034 14.0 0.2 13 5.8 0.1 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking NEMO PF11577.8 KND88492.1 - 0.049 13.6 0.7 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO UPRTase PF14681.6 KND88493.1 - 9e-79 263.7 0.0 1.1e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KND88493.1 - 0.0015 18.0 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 KND88494.1 - 2.7e-28 97.8 0.3 3.8e-28 97.3 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 KND88494.1 - 0.11 12.7 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 PHD-finger GTP_CH_N PF12471.8 KND88496.1 - 2.8e-66 223.0 0.0 1.5e-65 220.6 0.0 2.0 1 1 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KND88496.1 - 4.6e-16 58.8 0.0 9.1e-16 57.9 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II WD40 PF00400.32 KND88498.1 - 1.7e-20 73.0 14.1 0.00039 21.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88498.1 - 3e-14 53.1 6.1 1.9e-05 24.9 0.4 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND88498.1 - 2.7e-07 30.7 0.1 0.00099 19.0 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND88498.1 - 0.11 11.5 0.1 1.6 7.6 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4965 PF16335.5 KND88499.1 - 6.1e-63 211.6 0.3 5.8e-48 162.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KND88499.1 - 1.8e-51 174.9 0.0 3.3e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 KND88499.1 - 3.2e-42 144.9 0.6 5e-42 144.2 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KND88499.1 - 0.0046 16.5 0.3 0.01 15.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Acetyltransf_1 PF00583.25 KND88500.1 - 6.3e-13 49.0 0.0 9.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND88500.1 - 6.9e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND88500.1 - 5.4e-09 36.4 0.0 7.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND88500.1 - 8.2e-07 28.9 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KND88500.1 - 0.0049 16.9 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KND88500.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DNA_pol_B_thumb PF14791.6 KND88501.1 - 1.2e-22 79.8 0.2 2.7e-22 78.7 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KND88501.1 - 3.6e-20 72.3 0.0 5.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KND88501.1 - 7.8e-20 70.4 2.3 8.2e-20 70.4 0.9 1.8 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KND88501.1 - 1.6e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 KND88501.1 - 0.0043 17.4 0.0 0.0081 16.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 KND88501.1 - 0.016 15.8 0.0 0.98 10.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KND88501.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Herpes_UL4 PF03277.13 KND88502.1 - 0.048 13.3 0.5 0.054 13.1 0.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF2838 PF10998.8 KND88503.1 - 8.9e-45 151.5 9.4 8.9e-45 151.5 9.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 KND88503.1 - 0.025 14.5 2.0 0.043 13.7 2.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain SMC_N PF02463.19 KND88504.1 - 7.9e-59 198.7 0.0 1.9e-58 197.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND88504.1 - 4.8e-26 91.4 0.0 1.8e-25 89.5 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain TFIIE_alpha PF02002.17 KND88504.1 - 3.4e-13 49.3 0.1 1.4e-12 47.4 0.1 2.1 1 0 0 1 1 1 1 TFIIE alpha subunit AAA_21 PF13304.6 KND88504.1 - 2e-12 47.5 0.7 7.2e-05 22.7 0.1 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND88504.1 - 6.8e-08 32.1 0.1 1.9e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 KND88504.1 - 0.0029 17.8 0.0 0.14 12.4 0.0 3.4 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FPP PF05911.11 KND88504.1 - 7.5 4.6 81.9 0.039 12.1 38.7 4.0 3 1 0 4 4 4 0 Filament-like plant protein, long coiled-coil Peptidase_M14 PF00246.24 KND88505.1 - 4.6e-72 243.3 0.0 6.2e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 KND88506.1 - 1.4e-31 109.6 0.0 2.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 KND88506.1 - 1.6e-05 25.3 0.0 4.3e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 KND88506.1 - 8.8e-05 22.9 0.1 0.00023 21.5 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2 PF00096.26 KND88507.1 - 2.5e-05 24.5 17.0 0.32 11.6 0.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type Pox_G9-A16 PF03003.16 KND88507.1 - 0.045 13.5 0.2 0.09 12.5 0.2 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 zf-C2H2_4 PF13894.6 KND88507.1 - 0.051 14.4 18.6 1.1 10.2 0.3 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger TT_ORF2 PF02957.15 KND88507.1 - 0.077 13.9 1.7 0.21 12.5 1.7 1.8 1 0 0 1 1 1 0 TT viral ORF2 zf-TAZ PF02135.16 KND88507.1 - 0.1 13.0 4.0 0.18 12.3 1.8 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-C2HE PF16278.5 KND88507.1 - 0.15 12.5 0.9 7.1 7.2 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 KND88507.1 - 0.21 12.3 6.2 0.88 10.2 0.9 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain Methyltransf_16 PF10294.9 KND88508.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KND88508.1 - 0.0039 16.6 0.1 0.0055 16.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Vps39_2 PF10367.9 KND88509.1 - 2.4e-05 24.7 0.0 6.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KND88509.1 - 0.00074 19.8 0.1 0.014 15.7 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Docking PF08990.11 KND88509.1 - 0.12 12.0 0.1 0.33 10.6 0.1 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking CASP_C PF08172.12 KND88510.1 - 5.2e-95 317.6 0.0 5.2e-95 317.6 0.0 3.2 3 0 0 3 3 3 1 CASP C terminal bZIP_2 PF07716.15 KND88510.1 - 0.0014 18.7 6.1 0.0014 18.7 6.1 8.4 9 1 0 9 9 8 1 Basic region leucine zipper CENP-F_leu_zip PF10473.9 KND88510.1 - 0.012 15.7 5.0 0.012 15.7 5.0 5.8 5 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KND88510.1 - 0.017 15.1 68.5 0.44 10.6 2.6 6.9 5 2 1 6 6 6 0 TPR/MLP1/MLP2-like protein betaPIX_CC PF16523.5 KND88510.1 - 0.035 13.9 0.9 0.035 13.9 0.9 4.3 4 0 0 4 4 4 0 betaPIX coiled coil Fez1 PF06818.15 KND88510.1 - 0.19 12.1 48.8 0.29 11.6 5.4 4.0 2 1 2 4 4 4 0 Fez1 Shugoshin_N PF07558.11 KND88510.1 - 0.57 10.1 6.8 1.1 9.2 0.9 3.7 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 KND88510.1 - 0.71 10.4 60.6 0.82 10.2 0.9 5.5 2 1 3 5 5 5 0 Apg6 coiled-coil region DivIC PF04977.15 KND88510.1 - 0.86 9.4 44.3 0.041 13.6 2.0 6.6 7 1 1 8 8 8 0 Septum formation initiator NAD_binding_1 PF00175.21 KND88510.1 - 1.1 10.0 2.9 14 6.4 0.0 3.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4407 PF14362.6 KND88510.1 - 1.4 8.2 35.6 3.9 6.7 3.9 4.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 KND88510.1 - 1.9 8.6 44.1 2.6 8.2 0.5 6.2 5 1 0 5 5 5 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KND88510.1 - 4.6 7.7 37.8 1.5 9.3 3.7 6.5 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) Hydrolase_4 PF12146.8 KND88511.1 - 2.2e-53 181.0 0.4 2.8e-53 180.7 0.4 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND88511.1 - 9.1e-15 55.8 5.1 1.2e-14 55.5 5.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND88511.1 - 6.5e-12 45.6 0.4 7.4e-10 38.9 0.1 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND88511.1 - 0.00045 19.8 0.8 0.45 9.9 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KND88511.1 - 0.0016 17.4 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KND88511.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 KND88511.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 KND88511.1 - 0.12 12.0 0.4 0.82 9.3 0.1 2.0 2 0 0 2 2 2 0 Putative esterase PAF-AH_p_II PF03403.13 KND88511.1 - 0.24 9.9 0.2 11 4.4 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Cation_efflux PF01545.21 KND88512.1 - 3.1e-16 59.7 6.9 4.3e-16 59.2 6.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KND88512.1 - 1.3e-09 38.0 0.1 2.7e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter INO80_Ies4 PF08193.11 KND88512.1 - 0.38 10.7 4.7 0.64 10.0 4.7 1.4 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Glyco_transf_8 PF01501.20 KND88513.1 - 1.4e-18 67.4 0.0 1.2e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KND88513.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative zf-rbx1 PF12678.7 KND88514.1 - 1.6e-09 37.9 4.8 2.9e-09 37.1 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND88514.1 - 3.5e-08 33.6 5.4 7.7e-08 32.5 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KND88514.1 - 3.9e-05 23.5 2.0 0.00012 22.0 2.0 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KND88514.1 - 8e-05 22.6 0.6 0.00017 21.6 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KND88514.1 - 8e-05 22.4 3.5 0.00015 21.6 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND88514.1 - 0.00011 22.1 2.6 0.00023 21.1 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KND88514.1 - 0.00016 21.4 5.6 0.0022 17.8 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND88514.1 - 0.0011 18.5 0.4 0.0025 17.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KND88514.1 - 0.0059 16.4 2.8 0.0059 16.4 2.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND88514.1 - 0.042 13.7 6.8 0.33 10.9 6.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KND88514.1 - 0.25 11.1 2.3 2.7 7.8 2.3 2.3 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KND88514.1 - 1 9.6 3.1 4.5 7.5 3.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 KND88514.1 - 1.4 8.8 3.3 1.2 9.0 0.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain F-box-like PF12937.7 KND88516.1 - 0.0094 15.8 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like Phage_XkdX PF09693.10 KND88516.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) UPF0147 PF03685.13 KND88518.1 - 0.00029 20.8 1.0 0.11 12.6 0.0 3.4 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0147) BLOC1S3 PF15753.5 KND88518.1 - 1.3 9.1 8.1 0.77 9.9 4.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Fez1 PF06818.15 KND88518.1 - 9 6.7 19.9 3 8.3 17.0 1.7 2 0 0 2 2 2 0 Fez1 Pkinase PF00069.25 KND88519.1 - 4.3e-11 42.7 0.0 1.7e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88519.1 - 4.3e-08 32.8 0.0 5.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND88519.1 - 0.00029 20.9 1.5 0.085 12.8 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88519.1 - 0.0047 16.5 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KND88519.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KND88519.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Xan_ur_permease PF00860.20 KND88521.1 - 1.8e-16 59.9 24.4 1.2e-09 37.3 8.9 2.8 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.20 KND88521.1 - 0.0052 15.6 1.8 0.0052 15.6 1.8 2.7 2 1 1 3 3 3 2 Sulfate permease family MFS_MOT1 PF16983.5 KND88521.1 - 0.064 13.7 8.6 0.12 12.8 1.0 2.9 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily 7tm_2 PF00002.24 KND88522.1 - 5.4e-13 48.8 4.7 1e-12 47.9 4.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 KND88522.1 - 1e-11 44.5 8.3 1e-11 44.5 8.3 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KND88522.1 - 9.2e-08 31.7 2.7 1.2e-07 31.3 2.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 KND88522.1 - 7.2e-05 22.3 4.3 0.00011 21.7 4.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 KND88522.1 - 8.5e-05 21.7 10.5 0.0022 17.1 3.4 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region STE3 PF02076.15 KND88522.1 - 0.00011 21.6 3.2 0.00014 21.2 1.0 2.1 2 0 0 2 2 2 1 Pheromone A receptor Git3 PF11710.8 KND88522.1 - 0.015 15.1 15.0 0.044 13.5 15.0 1.8 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF805 PF05656.14 KND88522.1 - 0.41 11.1 5.9 0.74 10.2 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Ank_2 PF12796.7 KND88523.1 - 1e-12 48.5 0.1 2e-07 31.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND88523.1 - 9.7e-07 29.2 0.1 7e-05 23.3 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88523.1 - 8.6e-06 25.7 0.1 0.12 13.0 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KND88523.1 - 1.3e-05 25.4 0.1 0.019 15.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Peptidase_C12 PF01088.21 KND88524.1 - 1e-66 224.7 0.0 1.3e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KND88524.1 - 1.8e-09 37.3 0.2 3.5e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases YodL PF14191.6 KND88524.1 - 0.19 12.6 0.0 0.36 11.7 0.0 1.4 1 0 0 1 1 1 0 YodL-like RCC1 PF00415.18 KND88525.1 - 1.2e-49 166.7 15.1 1.3e-09 38.6 0.1 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND88525.1 - 6.9e-29 99.0 25.7 6.7e-07 29.0 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF2407 PF10302.9 KND88526.1 - 0.00075 20.0 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KND88526.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family S4 PF01479.25 KND88527.1 - 9e-15 54.1 0.0 1.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KND88527.1 - 0.015 15.1 0.1 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 S4 domain Fungal_trans PF04082.18 KND88528.1 - 1e-37 129.7 0.0 1.7e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88528.1 - 2.5e-08 33.9 5.9 5.5e-08 32.8 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dicty_REP PF05086.12 KND88528.1 - 0.087 10.8 2.9 0.12 10.4 2.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PHD PF00628.29 KND88528.1 - 0.22 11.4 2.4 0.49 10.3 2.4 1.6 1 0 0 1 1 1 0 PHD-finger FSA_C PF10479.9 KND88528.1 - 7.6 4.5 17.5 12 3.9 17.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fungal_trans PF04082.18 KND88529.1 - 9.3e-29 100.3 0.0 2.1e-28 99.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88529.1 - 1.4e-09 37.9 9.8 2.6e-09 37.1 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 KND88531.1 - 2.6e-70 237.4 0.0 3.3e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND88531.1 - 4.5e-12 46.2 1.3 7.7e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase family tRNA_int_end_N2 PF12928.7 KND88531.1 - 0.09 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term DUF1729 PF08354.10 KND88532.1 - 7.8e-159 528.2 0.0 2.3e-158 526.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 KND88532.1 - 4.7e-87 292.5 0.0 5.4e-86 289.0 0.0 2.7 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 KND88532.1 - 9.6e-54 181.2 0.3 2.3e-53 179.9 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 KND88532.1 - 3.1e-37 126.9 0.0 6.7e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 KND88532.1 - 4e-37 128.2 0.0 9.9e-37 126.9 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 KND88532.1 - 4.6e-25 88.3 0.0 1.2e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 KND88532.1 - 4.9e-23 81.5 0.0 7.7e-21 74.4 0.0 2.9 1 1 1 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta PCIF1_WW PF12237.8 KND88532.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain FAS_I_H PF18314.1 KND88533.1 - 4.7e-77 258.2 0.2 1.7e-76 256.4 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KND88533.1 - 3.2e-75 251.9 0.0 7.6e-75 250.7 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KND88533.1 - 2.1e-21 76.7 0.0 4.8e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 KND88533.1 - 3.6e-19 69.0 0.0 9.6e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 KND88533.1 - 1.6e-12 47.5 0.1 7e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 KND88533.1 - 0.0001 21.8 0.0 0.00047 19.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KND88533.1 - 0.00012 22.1 0.1 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 1 KR domain LSM PF01423.22 KND88534.1 - 3.9e-15 55.3 0.0 6.3e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND88534.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pkinase PF00069.25 KND88535.1 - 2.3e-09 37.0 0.0 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND88535.1 - 5.7e-06 25.8 0.0 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KND88535.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KND88536.1 - 3.7e-06 26.5 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CCDC154 PF15450.6 KND88536.1 - 0.012 14.2 0.5 0.016 13.8 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Yuri_gagarin PF15934.5 KND88536.1 - 0.033 14.0 0.1 0.18 11.6 0.0 1.9 1 1 0 2 2 2 0 Yuri gagarin Mif2_N PF15624.6 KND88536.1 - 4.5 8.0 13.3 7.1 7.3 13.3 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal APH PF01636.23 KND88537.1 - 1.4e-14 54.6 0.1 8.3e-14 52.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND88538.1 - 7.9e-16 58.1 0.0 2.2e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND88538.1 - 1.1e-12 47.9 0.0 1.4e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND88538.1 - 0.048 13.0 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88538.1 - 0.12 12.3 0.8 0.39 10.6 0.4 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KND88539.1 - 1.8e-47 161.9 0.0 2.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88539.1 - 4.8e-35 121.1 0.0 6e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND88539.1 - 8.7e-05 22.6 0.0 0.036 14.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KND88539.1 - 9.1e-05 21.9 0.0 0.0027 17.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KND88539.1 - 0.0001 21.4 0.0 0.063 12.2 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 KND88539.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KND88539.1 - 0.0024 17.3 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 KND88539.1 - 0.071 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC1 family FTA2 PF13095.6 KND88541.1 - 2e-06 27.6 0.0 4.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 PPR_2 PF13041.6 KND88547.1 - 9.3e-13 48.2 0.2 0.025 14.8 0.0 4.9 5 0 0 5 5 5 4 PPR repeat family PPR PF01535.20 KND88547.1 - 3e-09 36.5 2.2 0.02 15.1 0.0 4.9 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 KND88547.1 - 3.5e-09 36.6 0.1 0.18 11.9 0.0 4.2 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 KND88547.1 - 9.8e-06 25.2 0.0 0.016 14.9 0.0 3.9 4 0 0 4 4 4 1 PPR repeat COX5A PF02284.16 KND88547.1 - 0.022 14.8 1.2 1.3 9.1 0.0 3.7 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va Jun PF03957.13 KND88547.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Jun-like transcription factor TPR_16 PF13432.6 KND88547.1 - 4.9 7.9 9.5 15 6.4 5.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat LysM PF01476.20 KND88549.1 - 5.5e-10 39.1 0.0 0.097 12.7 0.0 3.2 3 0 0 3 3 3 3 LysM domain C5HCH PF17982.1 KND88549.1 - 0.71 10.1 5.4 0.59 10.3 1.1 2.5 2 0 0 2 2 2 0 NSD Cys-His rich domain PTR2 PF00854.21 KND88550.1 - 1.4e-74 251.3 2.9 2.8e-74 250.3 2.9 1.4 1 1 0 1 1 1 1 POT family HMGL-like PF00682.19 KND88550.1 - 3e-73 246.6 0.3 4.2e-73 246.1 0.3 1.2 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.24 KND88550.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel 2OG-FeII_Oxy PF03171.20 KND88552.1 - 4.3e-20 72.1 0.0 5.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KND88553.1 - 7.3e-118 394.2 0.0 1.6e-64 218.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cyclase PF04199.13 KND88554.1 - 6.1e-15 55.7 0.0 9.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase FAD_binding_3 PF01494.19 KND88555.1 - 8.4e-09 35.1 1.4 0.00031 20.1 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 KND88555.1 - 0.073 13.6 0.1 0.16 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1 PF00133.22 KND88557.1 - 2.8e-211 702.9 0.0 5.3e-210 698.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND88557.1 - 7.9e-29 100.6 0.1 1.9e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KND88557.1 - 2.6e-12 46.2 0.5 6.5e-05 21.8 0.1 5.1 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KND88557.1 - 1.9e-10 40.6 0.1 2.3e-06 27.3 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KND88557.1 - 0.00021 21.5 1.1 0.00021 21.5 1.1 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm DUF682 PF05081.12 KND88557.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF682) AP3D1 PF06375.11 KND88557.1 - 9.3 6.5 10.0 3 8.1 7.0 1.6 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Sec39 PF08314.11 KND88558.1 - 7.5e-258 857.9 0.0 8.7e-258 857.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RRM_1 PF00076.22 KND88559.1 - 1.5e-20 72.8 0.0 2.2e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND88559.1 - 8.8e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndufs5 PF10200.9 KND88560.1 - 0.00038 20.7 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KND88560.1 - 0.016 15.6 0.6 0.056 13.8 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) UPF0203 PF05254.12 KND88560.1 - 0.096 12.9 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 KND88560.1 - 0.1 12.8 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 KND88560.1 - 0.11 12.9 0.5 0.25 11.7 0.5 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Glyco_transf_41 PF13844.6 KND88564.1 - 5.1e-97 325.2 0.0 2.8e-48 164.5 0.0 3.1 2 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KND88564.1 - 2.7e-21 74.4 0.3 0.0023 17.6 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 KND88564.1 - 4.7e-18 63.8 1.2 0.13 12.5 0.1 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KND88564.1 - 3.6e-14 51.7 0.1 0.0021 18.1 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND88564.1 - 3.5e-13 49.0 1.2 0.013 15.2 0.0 6.2 3 2 3 6 6 6 5 TPR repeat TPR_12 PF13424.6 KND88564.1 - 3.7e-10 39.9 3.2 0.0087 16.3 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KND88564.1 - 5e-08 32.8 0.1 0.0036 17.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND88564.1 - 8.9e-08 32.7 1.0 0.0058 17.3 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KND88564.1 - 2.6e-07 30.3 3.9 0.86 9.6 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND88564.1 - 2.5e-06 27.8 2.2 0.056 14.3 0.0 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND88564.1 - 2.2e-05 24.2 0.2 1 9.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND88564.1 - 2.7e-05 24.6 0.2 0.061 13.9 0.0 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat BTAD PF03704.17 KND88564.1 - 0.0025 18.2 2.8 0.033 14.6 0.0 3.6 4 1 1 5 5 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KND88564.1 - 0.0055 16.8 1.5 0.11 12.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND88564.1 - 0.1 12.9 0.4 3.8 7.8 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Myb_DNA-binding PF00249.31 KND88565.1 - 8.2e-23 80.3 1.9 2.3e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND88565.1 - 8.2e-15 54.8 0.6 7.4e-12 45.3 0.0 2.7 2 1 1 3 3 2 2 Myb-like DNA-binding domain DUF4746 PF15928.5 KND88565.1 - 0.0036 16.8 2.9 0.0049 16.3 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) DDHD PF02862.17 KND88565.1 - 0.034 14.3 5.3 0.053 13.7 5.1 1.5 2 0 0 2 2 2 0 DDHD domain DUF2774 PF11242.8 KND88565.1 - 0.045 14.0 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) EOS1 PF12326.8 KND88565.1 - 0.33 10.9 1.2 0.56 10.1 1.2 1.5 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 KND88565.1 - 1.3 8.7 15.1 1.9 8.2 15.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 KND88565.1 - 1.4 8.9 33.2 2.2 8.2 33.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.8 KND88565.1 - 2.4 7.0 16.3 3.2 6.6 16.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.14 KND88565.1 - 4.1 7.3 15.2 7.2 6.5 15.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 KND88565.1 - 8.1 5.3 9.2 11 4.8 9.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1980 PF09323.10 KND88565.1 - 9.9 6.0 7.1 17 5.3 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sec23_trunk PF04811.15 KND88566.1 - 8e-78 261.4 0.0 1.1e-77 260.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KND88566.1 - 8.8e-30 103.3 0.2 1.9e-29 102.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KND88566.1 - 2e-24 85.4 0.1 4.6e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KND88566.1 - 1.5e-15 56.9 6.4 2.7e-15 56.1 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KND88566.1 - 1.2e-13 50.8 0.0 2.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KND88566.1 - 0.077 12.4 0.9 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 KND88567.1 - 9.3e-24 83.1 0.1 1.5e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KND88567.1 - 1.3e-16 60.8 0.2 2.2e-16 60.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Hce2 PF14856.6 KND88569.1 - 5e-16 58.9 0.0 6.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Ntox25 PF15530.6 KND88569.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 25 Orthopox_A36R PF05950.11 KND88570.1 - 1.1 9.4 2.6 1.3 9.2 2.0 1.4 1 1 0 1 1 1 0 Orthopoxvirus A36R protein LysM PF01476.20 KND88571.1 - 3.8e-08 33.3 0.1 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 KND88572.1 - 1.5e-09 37.8 0.1 0.0014 18.7 0.0 3.9 5 0 0 5 5 5 2 LysM domain DUF863 PF05904.11 KND88572.1 - 2.6 6.4 4.7 3.7 5.9 4.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) APH PF01636.23 KND88575.1 - 1.7e-05 24.9 0.1 2.1e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 KND88576.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KND88578.1 - 7.5e-43 146.8 0.0 1.1e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KND88578.1 - 1e-05 24.7 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S28 PF05577.12 KND88579.1 - 3.5e-44 151.3 0.1 3.8e-34 118.2 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 STN PF07660.14 KND88580.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain Lyase_1 PF00206.20 KND88581.1 - 2.3e-17 63.4 0.0 3.1e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KND88581.1 - 6.1e-15 55.5 0.0 1.7e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus PPV_E1_C PF00519.17 KND88581.1 - 0.0093 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase p450 PF00067.22 KND88582.1 - 3.7e-31 108.4 0.0 5.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 NinD PF17466.2 KND88583.1 - 0.023 14.8 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function PAN_4 PF14295.6 KND88584.1 - 0.0027 17.6 1.1 0.0059 16.5 1.1 1.6 1 0 0 1 1 1 1 PAN domain SecE PF00584.20 KND88585.1 - 4.1e-13 49.0 0.0 5.2e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Asparaginase_2 PF01112.18 KND88586.1 - 3.4e-69 233.2 3.6 5e-69 232.7 3.6 1.2 1 0 0 1 1 1 1 Asparaginase 2-Hacid_dh_C PF02826.19 KND88586.1 - 4.7e-35 120.5 0.0 1.2e-25 89.9 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Adaptin_binding PF10199.9 KND88587.1 - 0.09 13.4 2.9 0.91 10.1 0.0 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PTPA PF03095.15 KND88588.1 - 2.9e-115 384.9 0.0 3.3e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein HicB_lk_antitox PF15919.5 KND88589.1 - 0.053 13.6 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system DUF1664 PF07889.12 KND88589.1 - 0.22 11.6 1.2 8.7 6.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PV-1 PF06637.11 KND88589.1 - 6.7 5.4 13.9 1.4 7.7 9.0 2.2 2 1 1 3 3 3 0 PV-1 protein (PLVAP) bZIP_1 PF00170.21 KND88590.1 - 6.4e-08 32.6 3.0 1.2e-07 31.7 3.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor RTT107_BRCT_5 PF16770.5 KND88590.1 - 0.044 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain bZIP_2 PF07716.15 KND88590.1 - 0.16 12.0 5.6 0.37 10.9 5.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Complex1_LYR PF05347.15 KND88591.1 - 0.00022 21.2 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Velvet PF11754.8 KND88593.1 - 3.8e-42 145.0 2.0 1.3e-31 110.5 0.5 2.1 1 1 1 2 2 2 2 Velvet factor Acetyltransf_1 PF00583.25 KND88594.1 - 1.1e-09 38.5 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND88594.1 - 1.4e-07 31.8 0.0 2.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND88594.1 - 5.4e-07 29.6 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND88594.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Glyco_tran_WbsX PF14307.6 KND88594.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX FPP PF05911.11 KND88595.1 - 2.2e-05 22.9 15.7 2.2e-05 22.9 15.7 5.1 1 1 4 5 5 5 2 Filament-like plant protein, long coiled-coil Filament PF00038.21 KND88595.1 - 0.00046 19.9 122.0 0.052 13.1 4.2 5.9 1 1 2 4 4 4 3 Intermediate filament protein HOOK PF05622.12 KND88595.1 - 0.0006 18.1 11.2 0.0006 18.1 11.2 5.5 1 1 3 5 5 5 3 HOOK protein DUF4407 PF14362.6 KND88595.1 - 0.0052 16.2 15.4 0.0052 16.2 15.4 8.2 1 1 7 8 8 8 1 Domain of unknown function (DUF4407) Csm1_N PF18504.1 KND88595.1 - 0.019 15.3 0.5 0.019 15.3 0.5 13.2 7 4 7 16 16 16 0 Csm1 N-terminal domain DUF4201 PF13870.6 KND88595.1 - 0.021 14.6 0.7 0.021 14.6 0.7 8.1 1 1 4 7 7 7 0 Domain of unknown function (DUF4201) PKcGMP_CC PF16808.5 KND88595.1 - 2.9 7.8 32.9 2.4 8.1 0.1 8.5 6 3 2 9 9 9 0 Coiled-coil N-terminus of cGMP-dependent protein kinase 7TMR-DISM_7TM PF07695.11 KND88596.1 - 2.2 8.1 13.0 0.55 10.1 1.1 3.0 2 1 1 3 3 3 0 7TM diverse intracellular signalling Ubie_methyltran PF01209.18 KND88597.1 - 4.5e-77 258.5 0.0 5.6e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KND88597.1 - 1.2e-15 58.0 0.0 6.1e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND88597.1 - 8.7e-13 48.7 0.0 6.4e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND88597.1 - 9e-13 48.3 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND88597.1 - 4.8e-10 40.1 0.0 7.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND88597.1 - 3.5e-07 30.2 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND88597.1 - 0.049 13.2 0.0 0.39 10.3 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 KND88597.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase DUF2433 PF10360.9 KND88598.1 - 1.3e-49 167.5 0.0 1.9e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 KND88598.1 - 0.00044 20.8 0.0 0.00084 19.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND88598.1 - 0.0018 18.5 0.0 0.0072 16.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Zds_C PF08632.10 KND88599.1 - 3.3e-29 100.4 1.1 6.7e-29 99.4 1.1 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Complex1_30kDa PF00329.19 KND88600.1 - 5.7e-45 152.9 0.0 8e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Sec3_C PF09763.9 KND88601.1 - 4.5e-238 792.2 0.2 5.5e-238 791.9 0.2 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KND88601.1 - 1.9e-28 98.4 0.0 4.6e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KND88601.1 - 0.032 14.6 0.0 0.032 14.6 0.0 2.6 3 0 0 3 3 3 0 Sec3 exocyst complex subunit DUF2018 PF09442.10 KND88601.1 - 0.096 13.7 0.1 0.4 11.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) Vps52 PF04129.12 KND88601.1 - 0.1 11.3 1.6 0.17 10.6 0.2 1.9 2 0 0 2 2 2 0 Vps52 / Sac2 family GlutR_dimer PF00745.20 KND88601.1 - 0.27 11.7 2.2 2.7 8.5 0.2 3.5 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain HECT PF00632.25 KND88603.1 - 5.5e-72 242.8 0.0 9.6e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 KND88603.1 - 8.1e-05 22.6 0.5 0.77 10.2 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KND88603.1 - 0.0039 17.7 0.2 1 10.0 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat DUF2013 PF09431.10 KND88603.1 - 0.034 14.3 0.1 0.1 12.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) Arm PF00514.23 KND88603.1 - 0.036 14.1 8.9 0.99 9.5 0.1 5.2 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KND88603.1 - 0.089 12.3 0.1 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 CLASP N terminal MMS19_N PF14500.6 KND88603.1 - 0.41 10.2 3.4 3.9 7.0 0.3 3.5 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II E1_dh PF00676.20 KND88604.1 - 2.2e-84 282.9 0.0 2.7e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KND88604.1 - 0.0011 18.8 0.1 0.013 15.2 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 KND88604.1 - 0.025 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Redoxin PF08534.10 KND88604.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Redoxin DXP_synthase_N PF13292.6 KND88604.1 - 0.15 11.3 0.0 0.48 9.6 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Enkurin PF13864.6 KND88604.1 - 0.3 11.5 2.6 0.57 10.6 2.6 1.4 1 0 0 1 1 1 0 Calmodulin-binding Fe-ADH PF00465.19 KND88605.1 - 1.1e-100 337.0 0.0 1.4e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KND88605.1 - 2.4e-13 50.4 0.0 8.2e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 KND88605.1 - 0.03 14.0 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein F-box_4 PF15966.5 KND88606.1 - 0.00023 21.0 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 KND88606.1 - 0.0021 17.9 2.7 0.0028 17.5 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KND88606.1 - 0.0046 16.8 2.9 0.011 15.6 2.9 1.7 1 0 0 1 1 1 1 F-box-like Gpi16 PF04113.14 KND88607.1 - 2.8e-243 808.5 0.0 3.4e-243 808.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Patatin PF01734.22 KND88608.1 - 0.014 15.6 0.1 0.022 14.9 0.1 1.3 1 0 0 1 1 1 0 Patatin-like phospholipase Pkinase PF00069.25 KND88609.1 - 2.5e-13 50.0 0.0 3.3e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND88609.1 - 1.1e-06 28.2 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KND88609.1 - 8e-06 25.3 0.0 1.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND88609.1 - 0.0001 22.3 0.2 0.0002 21.4 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND88609.1 - 0.083 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Gly_transf_sug PF04488.15 KND88610.1 - 1.2e-06 29.0 0.0 2.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KND88610.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.15 KND88611.1 - 8.2e-12 45.6 0.0 1.8e-11 44.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TFIIA PF03153.13 KND88612.1 - 0.0041 17.2 16.9 0.0055 16.8 16.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 KND88612.1 - 0.2 10.3 13.4 0.25 9.9 13.4 1.1 1 0 0 1 1 1 0 Hamartin protein Nucleo_P87 PF07267.11 KND88612.1 - 7.7 5.2 18.9 11 4.7 18.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nuc_deoxyri_tr2 PF15891.5 KND88613.1 - 2.2e-32 111.6 0.0 3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like TPR_12 PF13424.6 KND88615.1 - 8.6e-10 38.8 10.5 1.4e-06 28.5 2.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND88615.1 - 2.9e-09 36.5 5.2 0.015 15.1 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND88615.1 - 7.8e-08 31.9 1.5 1.4 9.3 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KND88615.1 - 1.3e-07 31.2 5.7 0.48 10.6 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KND88615.1 - 2.8e-06 27.5 4.1 0.0087 16.3 0.3 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KND88615.1 - 2.4e-05 24.8 3.0 0.87 10.1 0.3 4.9 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KND88615.1 - 0.00037 21.1 7.0 4.7 8.3 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat AAA_lid_8 PF17868.1 KND88615.1 - 0.00092 19.1 1.6 0.76 9.7 0.1 3.5 2 1 1 3 3 3 2 AAA lid domain TPR_2 PF07719.17 KND88615.1 - 0.00096 19.1 5.0 28 5.1 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3860 PF12976.7 KND88615.1 - 0.013 15.5 0.3 4.5 7.4 0.0 3.5 1 1 2 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3860) Syntaxin-18_N PF10496.9 KND88615.1 - 0.023 14.9 2.0 1.9 8.8 0.2 3.3 1 1 2 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Paf67 PF10255.9 KND88615.1 - 0.039 13.0 0.0 0.5 9.3 0.0 2.4 1 1 2 3 3 3 0 RNA polymerase I-associated factor PAF67 Bombinin PF05298.11 KND88615.1 - 0.042 13.5 2.1 6.4 6.5 0.2 2.6 1 1 0 2 2 2 0 Bombinin NurA PF09376.10 KND88615.1 - 0.25 11.0 1.8 0.74 9.5 0.7 2.2 2 0 0 2 2 2 0 NurA domain His_kinase PF06580.13 KND88615.1 - 2.1 8.7 6.3 13 6.2 0.2 4.0 2 1 3 5 5 5 0 Histidine kinase 2OG-FeII_Oxy_2 PF13532.6 KND88616.1 - 9e-31 107.6 0.0 1.5e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HECT PF00632.25 KND88617.1 - 9.2e-64 215.8 0.0 1.3e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 KND88617.1 - 7e-24 83.8 1.1 1.4e-23 82.9 1.1 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 KND88618.1 - 4.8e-34 116.7 7.8 1.6e-28 99.0 1.4 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KND88618.1 - 2.3e-08 34.1 16.4 7.2e-07 29.3 2.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND88618.1 - 1.7e-06 28.3 1.1 1.7e-06 28.3 1.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KND88618.1 - 0.0012 19.5 14.8 0.98 10.4 0.1 5.4 5 0 0 5 5 5 1 C2H2-type zinc finger SnoaL_2 PF12680.7 KND88618.1 - 0.018 15.7 0.0 0.074 13.7 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain DUF629 PF04780.12 KND88618.1 - 0.039 12.5 1.3 0.2 10.2 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-DBF PF07535.12 KND88618.1 - 0.59 10.3 10.7 8.8 6.5 0.5 4.3 4 0 0 4 4 4 0 DBF zinc finger Podoplanin PF05808.11 KND88619.1 - 0.00012 22.3 4.9 0.00017 21.7 4.9 1.2 1 0 0 1 1 1 1 Podoplanin DUF4448 PF14610.6 KND88619.1 - 0.0009 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KND88619.1 - 0.0028 17.0 0.8 0.007 15.8 0.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 KND88619.1 - 0.03 14.3 3.8 0.1 12.5 3.8 2.0 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF3697 PF12478.8 KND88619.1 - 0.03 14.4 0.3 0.063 13.4 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 DUF4381 PF14316.6 KND88619.1 - 0.03 14.6 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4366 PF14283.6 KND88619.1 - 0.037 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3426 PF11906.8 KND88619.1 - 0.044 13.9 0.6 14 5.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3426) Rax2 PF12768.7 KND88619.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Cortical protein marker for cell polarity adh_short PF00106.25 KND88620.1 - 4.7e-41 140.4 0.5 6e-41 140.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND88620.1 - 9.4e-31 107.2 0.1 1.2e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KND88620.1 - 0.0004 20.3 0.1 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KND88620.1 - 0.0011 18.9 0.5 0.0024 17.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KND88620.1 - 0.005 16.3 0.1 0.007 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND88620.1 - 0.0095 15.5 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KND88620.1 - 0.019 15.2 0.3 0.063 13.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF1786 PF08735.10 KND88620.1 - 0.034 13.4 0.6 0.05 12.9 0.6 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) 2-Hacid_dh_C PF02826.19 KND88620.1 - 0.036 13.4 0.3 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KND88620.1 - 0.055 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 KND88620.1 - 0.074 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4754 PF15946.5 KND88620.1 - 0.075 13.3 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) DUF3320 PF11784.8 KND88620.1 - 0.077 13.0 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) PIR PF00399.19 KND88621.1 - 9.7e-23 79.1 73.2 2.9e-07 29.9 3.0 8.7 9 1 0 9 9 9 7 Yeast PIR protein repeat AA_permease PF00324.21 KND88622.1 - 1.3e-122 409.9 39.2 1.6e-122 409.6 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND88622.1 - 2.5e-32 112.2 41.6 3.3e-32 111.9 41.6 1.2 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 KND88623.1 - 4.3e-09 35.8 0.9 8.2e-09 34.9 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-U1 PF06220.12 KND88624.1 - 8e-06 25.5 1.6 1.6e-05 24.5 1.6 1.6 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.6 KND88624.1 - 0.065 13.5 1.1 2.7 8.2 0.2 2.3 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal DUF4554 PF15091.6 KND88624.1 - 0.17 10.8 2.7 0.24 10.3 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) NEMP PF10225.9 KND88624.1 - 1.4 8.5 2.7 2.6 7.7 2.7 1.3 1 0 0 1 1 1 0 NEMP family GET2 PF08690.10 KND88624.1 - 1.4 8.5 4.3 2.4 7.7 4.3 1.5 1 1 0 1 1 1 0 GET complex subunit GET2 Peptidase_S64 PF08192.11 KND88624.1 - 2 6.8 4.7 2.5 6.5 4.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_47 PF01532.20 KND88626.1 - 1.4e-128 429.7 0.0 1.6e-128 429.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rad10 PF03834.14 KND88627.1 - 1.5e-46 157.1 0.1 2.3e-46 156.5 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Ndc80_HEC PF03801.13 KND88628.1 - 4.7e-58 195.2 0.1 8.6e-58 194.3 0.1 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Ribosomal_L7Ae PF01248.26 KND88628.1 - 5e-20 71.0 2.0 1.1e-19 70.0 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF16 PF01519.16 KND88628.1 - 0.0023 18.4 6.1 0.0023 18.4 6.1 3.2 2 1 1 3 3 3 1 Protein of unknown function DUF16 TPR_MLP1_2 PF07926.12 KND88628.1 - 0.0084 16.2 14.2 0.0084 16.2 14.2 4.3 5 1 0 5 5 5 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 KND88628.1 - 0.0095 14.9 32.9 0.0097 14.8 10.8 3.2 3 0 0 3 3 3 2 Spc7 kinetochore protein Golgin_A5 PF09787.9 KND88628.1 - 0.12 11.9 41.7 0.82 9.1 11.8 3.6 1 1 3 4 4 4 0 Golgin subfamily A member 5 Ntox28 PF15605.6 KND88628.1 - 0.52 10.6 16.3 1.7 8.9 1.1 4.8 4 2 1 5 5 5 0 Bacterial toxin 28 DUF4510 PF14971.6 KND88628.1 - 0.74 10.1 8.8 0.037 14.4 1.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4510) Filament PF00038.21 KND88628.1 - 0.86 9.1 42.3 0.76 9.3 21.3 2.6 2 0 0 2 2 2 0 Intermediate filament protein FliJ PF02050.16 KND88628.1 - 1.2 9.4 26.9 0.062 13.5 3.5 3.3 3 1 0 3 3 2 0 Flagellar FliJ protein DUF948 PF06103.11 KND88628.1 - 2.7 8.3 8.8 9.7 6.5 1.0 4.8 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) ING PF12998.7 KND88628.1 - 4.1 8.0 16.3 0.3 11.7 3.4 3.9 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF4407 PF14362.6 KND88628.1 - 5 6.4 25.8 0.91 8.8 5.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 KND88628.1 - 5.6 7.5 9.3 11 6.6 0.3 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Lactamase_B_2 PF12706.7 KND88629.1 - 4.7e-29 101.3 0.1 7.4e-28 97.4 0.1 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KND88629.1 - 1.8e-08 34.5 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KND88629.1 - 0.028 14.4 5.1 0.13 12.2 2.8 2.7 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Ribosomal_L35Ae PF01247.18 KND88630.1 - 5.5e-38 129.0 0.7 2.2e-28 98.3 0.3 2.0 2 0 0 2 2 2 2 Ribosomal protein L35Ae RimM PF01782.18 KND88630.1 - 0.015 15.5 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain VMA21 PF09446.10 KND88631.1 - 3.4e-15 55.9 11.3 4.9e-15 55.4 11.3 1.3 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 KND88632.1 - 1.4e-26 93.0 0.2 1.4e-26 93.0 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) SNF2_N PF00176.23 KND88633.1 - 4.7e-50 170.3 0.0 8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND88633.1 - 2e-16 60.3 0.1 6.9e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND88633.1 - 4.6e-08 33.2 0.0 1.9e-07 31.2 0.0 2.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KND88633.1 - 1.7e-05 24.1 0.3 6.1e-05 22.4 0.0 1.9 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 KND88633.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DEAD PF00270.29 KND88633.1 - 0.012 15.4 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase BMFP PF04380.13 KND88633.1 - 0.11 13.0 0.2 0.41 11.2 0.2 2.0 1 0 0 1 1 1 0 Membrane fusogenic activity Ank_2 PF12796.7 KND88634.1 - 1.3e-21 77.0 0.2 6.3e-10 39.5 0.1 4.2 2 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND88634.1 - 1.5e-19 68.0 1.5 0.0011 19.3 0.0 7.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 KND88634.1 - 3.9e-17 62.4 0.1 0.0015 19.1 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KND88634.1 - 1.4e-16 60.1 0.1 0.0021 18.4 0.0 5.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KND88634.1 - 1.2e-15 57.4 0.1 1.3e-08 34.9 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KND88634.1 - 2.1 7.7 4.6 5.1 6.4 4.6 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Myb_DNA-bind_6 PF13921.6 KND88635.1 - 0.0032 17.7 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain GDPD PF03009.17 KND88636.1 - 6.2e-43 147.4 0.0 4.6e-41 141.3 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KND88636.1 - 8.3e-24 84.0 0.5 6.5e-09 36.3 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND88636.1 - 1.6e-18 66.8 1.4 1.8e-05 25.2 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88636.1 - 3e-17 60.9 1.4 0.003 17.9 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KND88636.1 - 5.5e-17 61.6 1.4 0.0032 17.8 0.0 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KND88636.1 - 4.5e-13 49.0 1.4 0.0088 16.5 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat SPX PF03105.19 KND88636.1 - 2.8e-08 34.1 0.2 7.8e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 SPX domain FAD_binding_3 PF01494.19 KND88638.1 - 1e-22 80.9 0.4 3.1e-22 79.3 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain PhageMin_Tail PF10145.9 KND88638.1 - 0.00026 20.9 0.8 0.0004 20.3 0.8 1.2 1 0 0 1 1 1 1 Phage-related minor tail protein TT1725 PF18324.1 KND88638.1 - 0.05 13.7 0.0 8.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Hypothetical protein TT1725 DIT1_PvcA PF05141.12 KND88639.1 - 3.9e-94 315.2 0.0 5.2e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 KND88639.1 - 1.5e-22 80.7 0.0 3.1e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family WW_1 PF18507.1 KND88639.1 - 0.022 14.4 0.1 0.047 13.4 0.1 1.5 1 0 0 1 1 1 0 WW domain FAD_binding_4 PF01565.23 KND88640.1 - 5.8e-30 103.9 3.2 9.5e-30 103.2 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND88640.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.25 KND88641.1 - 1e-15 57.7 0.0 1.7e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KND88641.1 - 5.1e-05 23.3 0.1 7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND88641.1 - 0.007 15.9 0.1 0.025 14.1 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TetR_C_11 PF16859.5 KND88641.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DEAD PF00270.29 KND88642.1 - 6.6e-42 143.3 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND88642.1 - 8.3e-28 97.0 0.0 3.5e-27 94.9 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND88642.1 - 0.00032 20.8 0.0 0.0019 18.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Glypican PF01153.19 KND88642.1 - 6.2 5.5 5.5 13 4.5 5.5 1.5 1 0 0 1 1 1 0 Glypican TPR_MLP1_2 PF07926.12 KND88643.1 - 2e-39 134.6 52.4 5.6e-38 129.9 27.6 19.2 7 4 8 17 17 17 5 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 KND88643.1 - 6.9e-06 26.1 21.4 6.9e-06 26.1 21.4 18.9 7 5 10 19 19 19 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 KND88643.1 - 0.0012 19.2 16.3 0.0012 19.2 16.3 15.6 4 2 8 14 14 14 3 Autophagy protein 16 (ATG16) JIP_LZII PF16471.5 KND88643.1 - 0.02 15.1 0.6 0.02 15.1 0.6 22.2 20 8 5 25 25 25 0 JNK-interacting protein leucine zipper II Pox_A_type_inc PF04508.12 KND88643.1 - 7.6 6.6 24.9 4.1 7.4 0.3 8.0 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat Lactamase_B_2 PF12706.7 KND88644.1 - 7.2e-08 32.2 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 KND88644.1 - 2.4e-05 24.5 0.0 6.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 KND88644.1 - 0.0019 18.3 0.1 0.0047 17.0 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KND88644.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain p450 PF00067.22 KND88645.1 - 3.6e-25 88.6 0.0 4.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KND88646.1 - 2e-31 109.3 0.0 2.8e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3435 PF11917.8 KND88648.1 - 7.2e-10 38.4 0.0 8.4e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Sel1 PF08238.12 KND88650.1 - 3.8e-38 129.0 27.5 7.4e-06 26.5 0.4 7.5 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.15 KND88652.1 - 1.2e-288 958.0 0.3 1.7e-288 957.6 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KND88652.1 - 1.4e-13 51.2 5.5 5.5e-13 49.3 5.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND88652.1 - 1.6e-10 41.3 0.0 3.1e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KND88652.1 - 4.5e-05 23.0 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KND88652.1 - 0.0028 17.5 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Pkinase PF00069.25 KND88653.1 - 1.1e-66 224.9 0.0 1.5e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88653.1 - 1.9e-39 135.5 0.0 2.7e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KND88653.1 - 2.9e-07 30.6 0.0 0.00031 20.9 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KND88653.1 - 1.9e-05 24.1 0.0 5e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KND88653.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND88653.1 - 0.015 14.1 0.1 0.038 12.8 0.1 1.6 1 0 0 1 1 1 0 Fungal protein kinase RAMP4 PF06624.12 KND88653.1 - 0.019 15.0 0.0 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Sushi_2 PF09014.10 KND88653.1 - 0.16 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain Haspin_kinase PF12330.8 KND88653.1 - 0.2 10.5 0.6 0.39 9.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain OPA3 PF07047.12 KND88654.1 - 4.8e-35 120.1 0.1 4.8e-35 120.1 0.1 1.8 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Adaptin_binding PF10199.9 KND88654.1 - 0.033 14.8 4.0 0.085 13.5 3.3 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 XhlA PF10779.9 KND88654.1 - 0.55 10.5 2.6 1.2 9.4 2.6 1.5 1 0 0 1 1 1 0 Haemolysin XhlA SBDS PF01172.18 KND88656.1 - 5.7e-25 87.2 0.1 6.6e-25 87.0 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ion_trans_2 PF07885.16 KND88657.1 - 2.9e-34 116.9 25.8 6.3e-18 64.5 4.7 3.5 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 KND88657.1 - 0.24 10.6 20.1 0.025 13.8 3.9 3.1 2 1 0 2 2 2 0 Ion transport protein SieB PF14163.6 KND88657.1 - 0.61 9.6 2.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B Stm1_N PF09598.10 KND88657.1 - 0.81 10.6 3.0 2.1 9.2 3.0 1.7 1 0 0 1 1 1 0 Stm1 Zip PF02535.22 KND88657.1 - 2.5 7.2 9.6 6.6 5.9 9.6 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 KND88657.1 - 8.7 6.1 10.5 19 4.9 10.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.16 KND88657.1 - 9.2 6.2 6.2 6.4 6.7 3.5 2.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_2_C PF02836.17 KND88660.1 - 5.2e-96 321.3 1.2 8.1e-96 320.7 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KND88660.1 - 4.7e-46 157.4 0.0 1e-45 156.2 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KND88660.1 - 7e-39 133.4 0.2 1.4e-38 132.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KND88660.1 - 3e-21 75.7 0.0 6.6e-20 71.4 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Peptidase_M20 PF01546.28 KND88660.1 - 9.4e-21 74.5 0.0 4.8e-20 72.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_2 PF00703.21 KND88660.1 - 1.5e-10 41.7 0.0 3.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 WD40 PF00400.32 KND88660.1 - 7.4e-09 36.1 13.6 0.051 14.5 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Peptidase_M28 PF04389.17 KND88660.1 - 0.0016 18.2 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ANAPC4_WD40 PF12894.7 KND88660.1 - 0.0031 17.8 0.9 1.6 9.1 0.0 3.7 4 0 0 4 4 3 1 Anaphase-promoting complex subunit 4 WD40 domain M20_dimer PF07687.14 KND88660.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain Ge1_WD40 PF16529.5 KND88660.1 - 0.028 13.4 0.1 0.062 12.3 0.1 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Invas_SpaK PF03519.14 KND88660.1 - 0.047 13.8 0.1 5.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Invasion protein B family Ribosomal_L20 PF00453.18 KND88660.1 - 0.074 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L20 Peptidase_M42 PF05343.14 KND88660.1 - 0.21 10.5 0.0 0.48 9.4 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase 4HBT_3 PF13622.6 KND88662.1 - 1.3e-45 156.7 0.8 1.5e-45 156.4 0.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_2 PF00891.18 KND88663.1 - 6.4e-17 61.6 0.0 9.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain WD40 PF00400.32 KND88665.1 - 7.1e-40 134.3 18.6 2e-05 25.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88665.1 - 1.3e-09 38.2 0.9 0.9 9.9 0.0 6.4 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 KND88665.1 - 4.2e-09 36.2 0.7 8.4e-09 35.2 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND88665.1 - 2.7e-08 33.5 0.1 7e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 KND88665.1 - 0.0037 16.9 0.5 1.4 8.4 0.2 2.8 2 0 0 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 KND88665.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 KND88665.1 - 0.017 13.8 5.7 21 3.6 0.0 5.0 2 1 2 5 5 5 0 Nucleoporin Nup120/160 Pkinase PF00069.25 KND88666.1 - 6.4e-18 65.1 0.0 9.3e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88666.1 - 1.1e-14 54.3 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 KND88666.1 - 2.1e-07 31.5 0.0 1.1 9.9 0.0 4.1 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND88666.1 - 1.7e-06 27.9 0.1 0.66 10.7 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KND88666.1 - 0.00014 22.3 0.0 6.1 7.5 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Kdo PF06293.14 KND88666.1 - 0.00051 19.5 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88666.1 - 0.0093 15.9 0.0 0.035 14.0 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND88666.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ank_5 PF13857.6 KND88666.1 - 0.05 13.9 0.8 1.4 9.4 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Peptidase_MA_2 PF13485.6 KND88666.1 - 0.13 11.9 0.2 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase MA superfamily Kdo PF06293.14 KND88667.1 - 0.00068 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cutinase PF01083.22 KND88667.1 - 0.0033 17.4 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 KND88667.1 - 0.0073 16.9 0.0 0.026 15.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.12 KND88667.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) CdhD PF03599.16 KND88667.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Ank_2 PF12796.7 KND88668.1 - 1.7e-43 147.1 0.0 5.5e-15 55.7 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 KND88668.1 - 6.8e-38 127.5 0.5 6.3e-08 32.7 0.0 7.3 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 KND88668.1 - 1.6e-36 124.2 0.7 6.9e-13 48.8 0.1 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88668.1 - 5.6e-31 103.1 0.1 0.00013 22.1 0.0 8.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 KND88668.1 - 3.2e-30 103.8 0.6 8.3e-10 38.7 0.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) NACHT PF05729.12 KND88668.1 - 5.8e-10 39.3 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND88668.1 - 6.4e-08 33.2 0.0 2.2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND88668.1 - 1.1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KND88668.1 - 0.0089 15.3 0.1 0.53 9.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.22 KND88668.1 - 0.054 13.9 0.0 0.18 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 KND88668.1 - 0.098 13.1 0.0 0.38 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KND88668.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Glyco_hydro_18 PF00704.28 KND88670.1 - 2e-69 234.7 1.1 2.8e-69 234.2 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KND88670.1 - 1.8e-13 50.7 18.0 1.8e-13 50.7 18.0 4.1 4 0 0 4 4 4 1 Chitin recognition protein Glyco_hydro_85 PF03644.13 KND88670.1 - 0.0015 18.0 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 NPC1_N PF16414.5 KND88672.1 - 2e-81 273.1 8.9 3.1e-81 272.5 8.9 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KND88672.1 - 1.3e-70 238.5 10.0 9e-44 149.8 0.0 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KND88672.1 - 1.3e-49 168.0 3.9 1.3e-49 168.0 3.9 3.1 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KND88672.1 - 7.3e-07 28.4 37.4 0.00029 19.9 14.1 2.8 2 1 0 2 2 2 2 MMPL family Mannosyl_trans2 PF04188.13 KND88673.1 - 1.3e-51 176.4 5.6 3.3e-51 175.0 5.6 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) MR_MLE_C PF13378.6 KND88674.1 - 1.1e-58 198.4 0.0 1.8e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KND88674.1 - 0.0078 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 KND88674.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Hexapep PF00132.24 KND88675.1 - 9.3e-09 34.7 13.1 3.5e-06 26.5 1.1 3.7 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KND88675.1 - 0.015 14.3 0.4 0.037 13.0 0.3 1.7 1 1 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 KND88675.1 - 0.2 11.4 16.2 1.1 9.1 4.3 4.1 3 2 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 KND88676.1 - 4e-46 156.7 0.0 6.1e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KND88676.1 - 3.1e-29 100.9 1.5 3.4e-29 100.8 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KND88676.1 - 4.6e-09 36.0 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.14 KND88677.1 - 2e-18 66.7 0.0 4.6e-18 65.5 0.0 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Smr PF01713.21 KND88678.1 - 0.00046 20.5 0.5 0.0026 18.1 0.2 2.3 3 0 0 3 3 3 1 Smr domain CUE PF02845.16 KND88678.1 - 0.0028 17.3 0.1 0.0065 16.1 0.1 1.7 1 0 0 1 1 1 1 CUE domain DUF1771 PF08590.10 KND88678.1 - 0.14 12.5 8.3 0.33 11.4 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) LytR_C PF13399.6 KND88678.1 - 5.9 8.0 6.2 3.3 8.8 0.0 3.2 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Pkinase PF00069.25 KND88679.1 - 4.3e-19 68.9 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND88679.1 - 0.00028 20.3 0.0 0.26 10.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase SET PF00856.28 KND88680.1 - 1.6e-10 41.6 0.0 6.4e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_16 PF13432.6 KND88680.1 - 0.00012 22.7 1.7 0.00012 22.7 1.7 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND88680.1 - 0.00031 21.2 1.2 0.47 11.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND88680.1 - 0.038 14.1 7.7 6.7 7.1 0.1 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TRAPP PF04051.16 KND88680.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component ANAPC3 PF12895.7 KND88680.1 - 0.68 10.2 3.8 0.39 11.0 0.7 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Amidohydro_3 PF07969.11 KND88682.1 - 2.5e-37 129.5 0.0 4.1e-37 128.8 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KND88682.1 - 1.5e-06 27.8 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF1304 PF06993.12 KND88683.1 - 0.26 11.3 3.8 0.1 12.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) APH PF01636.23 KND88684.1 - 2.7e-07 30.8 0.2 1.5e-06 28.3 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family HEAT_EZ PF13513.6 KND88685.1 - 2.5e-20 72.5 4.7 9.1e-08 32.5 0.2 7.6 9 0 0 9 9 9 4 HEAT-like repeat HEAT PF02985.22 KND88685.1 - 8.2e-20 69.2 3.3 0.0062 16.7 0.0 8.5 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 KND88685.1 - 8.8e-17 61.3 2.6 0.03 14.7 0.0 7.6 5 1 3 8 8 8 6 HEAT repeats Cnd1 PF12717.7 KND88685.1 - 8.3e-06 25.9 0.0 0.39 10.8 0.0 4.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KND88685.1 - 9.4e-06 24.5 0.0 0.17 10.4 0.0 4.5 4 2 1 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 KND88685.1 - 1.1e-05 25.9 0.0 0.19 12.3 0.0 4.7 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 KND88685.1 - 2.4e-05 24.2 0.1 0.00017 21.4 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 KND88685.1 - 0.00018 21.3 0.0 3.1 7.5 0.0 3.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Arm PF00514.23 KND88685.1 - 0.00068 19.6 0.1 0.53 10.4 0.0 4.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 KND88685.1 - 0.025 14.7 3.9 0.5 10.6 0.1 3.8 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 KND88685.1 - 0.055 13.8 1.4 45 4.5 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion GyrI-like PF06445.15 KND88685.1 - 0.072 13.4 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 GyrI-like small molecule binding domain DUF747 PF05346.11 KND88686.1 - 4.4e-118 394.4 7.6 5.6e-118 394.1 7.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DLH PF01738.18 KND88686.1 - 1.6e-25 89.9 0.2 2.3e-25 89.4 0.2 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family HnRNP_M PF11532.8 KND88686.1 - 0.6 10.4 2.1 0.74 10.1 0.7 1.9 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M Pkinase PF00069.25 KND88688.1 - 5.9e-29 101.2 0.0 1e-21 77.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND88688.1 - 1.5e-20 73.6 0.0 2.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND88688.1 - 0.0085 15.5 0.2 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family BDV_P10 PF06515.11 KND88688.1 - 0.098 12.7 1.5 0.3 11.2 1.5 1.9 1 0 0 1 1 1 0 Borna disease virus P10 protein TPR_MLP1_2 PF07926.12 KND88688.1 - 0.21 11.6 5.1 0.38 10.8 5.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KND88688.1 - 0.23 11.9 3.4 0.63 10.5 3.4 1.7 1 0 0 1 1 1 0 Cell division protein ZapB IFT20 PF14931.6 KND88688.1 - 0.47 10.6 3.8 1.1 9.5 3.8 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 TMF_DNA_bd PF12329.8 KND88688.1 - 1.4 8.9 6.1 4.4 7.4 3.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding MMR_HSR1 PF01926.23 KND88689.1 - 4.7e-17 62.1 0.0 8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KND88689.1 - 4.8e-07 30.0 0.1 0.0012 18.9 0.5 2.4 1 1 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 KND88689.1 - 0.00029 20.8 0.1 0.0086 16.0 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KND88689.1 - 0.00062 19.4 0.0 0.0039 16.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 KND88689.1 - 0.0024 18.0 0.5 1 9.5 0.0 2.5 2 1 0 2 2 2 2 AAA domain FeoB_N PF02421.18 KND88689.1 - 0.024 14.1 0.1 0.065 12.8 0.1 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.18 KND88689.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.18 KND88689.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.16 KND88689.1 - 0.06 12.7 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 AIG1 family Roc PF08477.13 KND88689.1 - 0.077 13.2 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KND88689.1 - 0.24 10.4 0.0 0.53 9.3 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) zf-C3HC PF07967.13 KND88690.1 - 2.3e-36 124.7 0.2 5.7e-32 110.5 0.3 2.2 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 KND88690.1 - 5.1e-26 90.7 0.1 1.6e-25 89.1 0.1 1.9 1 0 0 1 1 1 1 Rsm1-like SRP40_C PF05022.12 KND88691.1 - 1.1e-19 71.0 3.4 1.1e-19 71.0 3.4 2.9 3 0 0 3 3 3 1 SRP40, C-terminal domain A_deaminase_N PF08451.11 KND88692.1 - 0.0012 19.1 0.0 0.003 17.8 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Pkinase PF00069.25 KND88694.1 - 1.8e-38 132.4 0.1 3.4e-38 131.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88694.1 - 1.3e-22 80.3 0.1 1.9e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND88694.1 - 0.11 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase BLM10_mid PF16507.5 KND88696.1 - 6.8e-197 655.3 0.0 1e-196 654.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KND88696.1 - 2.6e-30 104.2 0.0 2e-29 101.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KND88696.1 - 8.2e-22 77.3 0.2 2.4e-21 75.8 0.2 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KND88696.1 - 0.022 15.0 0.1 46 4.7 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 KND88696.1 - 0.045 14.3 0.1 2.9 8.5 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat ABATE PF07336.11 KND88696.1 - 5 7.8 6.0 4.7 7.9 1.7 3.1 3 0 0 3 3 3 0 Putative stress-induced transcription regulator Tim17 PF02466.19 KND88697.1 - 1.2e-31 109.3 7.3 1.6e-31 109.0 7.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SE PF08491.10 KND88698.1 - 1.3e-87 293.4 0.0 1.7e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 KND88698.1 - 8.8e-10 38.7 0.3 1.8e-07 31.1 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND88698.1 - 1e-08 34.8 2.1 3.5e-05 23.2 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND88698.1 - 1.5e-05 25.1 0.4 3.3e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND88698.1 - 0.00011 21.4 0.4 0.00066 18.9 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 KND88698.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KND88698.1 - 0.00031 20.0 0.3 0.0005 19.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KND88698.1 - 0.00032 20.2 0.5 0.00063 19.2 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND88698.1 - 0.0013 19.2 0.2 0.0033 17.9 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND88698.1 - 0.0015 17.8 0.1 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND88698.1 - 0.0045 16.1 0.1 0.083 11.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 KND88698.1 - 0.0053 16.4 0.1 0.0094 15.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KND88698.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KND88698.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 KND88698.1 - 0.047 13.8 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KND88698.1 - 0.054 12.2 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Mito_carr PF00153.27 KND88700.1 - 1.3e-58 194.9 0.0 8.2e-21 73.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein RSN1_7TM PF02714.15 KND88702.1 - 1.5e-75 254.1 22.7 1.5e-75 254.1 22.7 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND88702.1 - 2.5e-43 147.6 0.1 2.5e-43 147.6 0.1 4.2 4 1 3 7 7 7 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND88702.1 - 1.8e-29 103.2 0.4 1.5e-17 64.4 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KND88702.1 - 2.6e-16 59.6 0.0 7.1e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter APH PF01636.23 KND88703.1 - 5.2e-14 52.8 0.0 1.7e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88703.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND88703.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 KND88704.1 - 8.4e-16 58.6 0.0 1.5e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND88704.1 - 6.9e-06 25.8 0.0 1.8e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND88704.1 - 0.019 14.6 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 KND88704.1 - 0.085 12.2 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KND88704.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain PEMT PF04191.13 KND88705.1 - 5.3e-57 190.8 9.0 6.7e-35 119.7 1.5 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 KND88705.1 - 0.017 15.7 0.1 0.32 11.6 0.1 2.3 1 1 0 1 1 1 0 SKICH domain HECW_N PF16562.5 KND88705.1 - 0.024 14.4 0.0 0.07 12.9 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 eIF3g PF12353.8 KND88706.1 - 2.1e-44 150.9 2.2 4.4e-44 149.9 2.2 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KND88706.1 - 1.7e-15 56.6 0.0 3.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_H2_suC PF08615.11 KND88706.1 - 0.022 14.9 0.3 0.04 14.1 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-CCCH_7 PF18586.1 KND88706.1 - 0.032 14.6 0.2 0.062 13.6 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 IBR PF01485.21 KND88707.1 - 6.4e-14 51.9 36.7 1e-08 35.2 8.1 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 KND88707.1 - 0.00018 21.3 2.9 0.00018 21.3 2.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND88707.1 - 0.00019 21.7 7.2 0.00019 21.7 7.2 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 KND88707.1 - 0.00047 20.1 8.1 0.0016 18.4 8.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DUF2158 PF09926.9 KND88707.1 - 0.0053 16.5 0.6 0.011 15.5 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized small protein (DUF2158) DUF1460 PF07313.12 KND88707.1 - 0.051 13.0 0.3 0.086 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-C3HC4_4 PF15227.6 KND88707.1 - 1.3 9.3 16.5 0.95 9.7 6.7 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF676 PF05057.14 KND88708.1 - 2.4e-43 148.2 0.0 3.9e-28 98.5 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Zn_clus PF00172.18 KND88709.1 - 2.5e-09 37.1 8.0 2.5e-09 37.1 8.0 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND88709.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Lactonase PF10282.9 KND88710.1 - 1.1e-71 241.9 0.0 2.7e-71 240.6 0.0 1.6 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 KND88710.1 - 0.9 10.1 5.1 12 6.5 0.1 4.3 5 1 0 5 5 5 0 PQQ-like domain Rad51 PF08423.11 KND88711.1 - 3.6e-11 42.8 0.0 2e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 KND88711.1 - 3.8e-07 29.7 0.0 7.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.17 KND88711.1 - 5.9e-06 26.1 0.0 2.3e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein RecA PF00154.21 KND88711.1 - 5.2e-05 22.8 0.2 0.00027 20.5 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 KND88711.1 - 5.3e-05 22.9 0.6 0.00058 19.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.15 KND88711.1 - 0.0001 21.7 0.1 0.0013 18.1 0.1 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 KND88711.1 - 0.00011 22.7 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KND88711.1 - 0.00013 21.5 0.1 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 KND88711.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KND88711.1 - 0.00024 21.1 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 KND88711.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain IPT PF01745.16 KND88711.1 - 0.0035 16.8 0.2 0.0063 15.9 0.2 1.4 1 0 0 1 1 1 1 Isopentenyl transferase NB-ARC PF00931.22 KND88711.1 - 0.0089 15.2 0.2 0.014 14.6 0.2 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 KND88711.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND88711.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KND88711.1 - 0.048 13.8 0.2 0.22 11.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND88711.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KND88711.1 - 0.084 13.2 0.1 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KND88711.1 - 0.089 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KND88711.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.6 KND88712.1 - 7.7e-07 29.3 11.0 1.8e-05 24.9 3.5 4.9 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 KND88712.1 - 1e-05 25.7 14.0 0.00041 20.6 4.5 3.6 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND88712.1 - 0.047 14.6 3.1 0.047 14.6 3.1 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND88712.1 - 0.048 14.0 0.4 0.048 14.0 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.9 KND88712.1 - 0.39 10.4 0.7 0.81 9.4 0.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TIM21 PF08294.11 KND88713.1 - 1.2e-44 151.7 0.0 1.5e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 TIM21 ApbE PF02424.15 KND88713.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 ApbE family FAD-oxidase_C PF02913.19 KND88713.1 - 0.061 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Coa1 PF08695.10 KND88713.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Glycos_transf_2 PF00535.26 KND88716.1 - 4.6e-23 81.9 0.0 8e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KND88716.1 - 6.4e-08 32.8 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KND88716.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CPSase_L_D2 PF02786.17 KND88717.1 - 5.3e-112 372.4 0.8 2.2e-84 282.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KND88717.1 - 6.3e-48 161.8 0.0 1.6e-47 160.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KND88717.1 - 4.6e-47 160.3 0.0 1.1e-46 159.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KND88717.1 - 1.3e-46 158.3 0.2 4.8e-46 156.5 0.0 2.2 3 0 0 3 3 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KND88717.1 - 1.5e-39 135.1 0.2 3.5e-39 133.9 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KND88717.1 - 1.3e-30 106.6 0.0 3.4e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KND88717.1 - 6e-23 80.9 0.1 1e-21 76.9 0.0 3.0 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KND88717.1 - 9.8e-17 61.2 2.4 2.4e-07 30.5 0.4 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KND88717.1 - 5.5e-15 55.4 0.4 1.6e-06 27.8 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KND88717.1 - 8.5e-11 41.7 0.0 1.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KND88717.1 - 3.4e-06 27.0 0.8 0.00037 20.3 0.1 2.9 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KND88717.1 - 0.00028 21.0 0.9 0.83 9.7 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KND88717.1 - 0.0014 18.5 0.1 0.23 11.3 0.0 2.9 2 0 0 2 2 2 1 DJ-1/PfpI family GARS_A PF01071.19 KND88717.1 - 0.0081 16.0 1.4 1.2 8.9 0.1 3.2 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SMK-1 PF04802.15 KND88718.1 - 4.6e-84 281.0 0.1 9.2e-84 280.0 0.1 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Shadoo PF14999.6 KND88718.1 - 0.15 12.2 10.9 0.36 10.9 10.9 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Kelch_5 PF13854.6 KND88719.1 - 1.4e-11 44.1 2.3 1.3e-10 41.0 0.5 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 KND88719.1 - 2.3e-07 30.7 1.7 0.17 12.0 0.2 4.8 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 KND88719.1 - 9.6e-06 25.8 0.3 9.6e-06 25.8 0.3 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KND88719.1 - 0.00012 21.6 5.4 0.21 11.2 0.5 3.6 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 KND88719.1 - 0.0022 18.2 4.5 0.2 12.0 0.7 4.3 3 1 1 4 4 4 1 Kelch motif DAG1 PF05454.11 KND88719.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4448 PF14610.6 KND88719.1 - 0.0062 16.3 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) CDC73_C PF05179.14 KND88721.1 - 1.3e-56 190.7 0.0 1.9e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal RGS PF00615.19 KND88722.1 - 4.6e-36 123.7 0.5 1.5e-35 122.0 0.2 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 KND88722.1 - 2e-25 88.6 0.0 1.6e-21 76.2 0.0 3.6 4 0 0 4 4 4 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) 2-Hacid_dh PF00389.30 KND88722.1 - 0.14 11.9 0.2 0.89 9.2 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MarB PF13999.6 KND88723.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 MarB protein AAA_16 PF13191.6 KND88725.1 - 5.3e-13 49.7 0.0 1.5e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 KND88725.1 - 3.5e-11 42.8 7.2 6.2e-11 42.0 7.2 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 KND88725.1 - 1.4e-09 38.5 0.0 3e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PHD_2 PF13831.6 KND88725.1 - 1.9e-09 36.9 1.7 1.9e-09 36.9 1.7 1.6 2 0 0 2 2 1 1 PHD-finger AAA_22 PF13401.6 KND88725.1 - 3.1e-09 37.2 0.0 5.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KND88725.1 - 8.5e-06 25.8 0.0 4.1e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KND88725.1 - 7.2e-05 23.2 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KND88725.1 - 0.00026 20.4 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_30 PF13604.6 KND88725.1 - 0.00036 20.3 0.0 0.00077 19.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KND88725.1 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KND88725.1 - 0.00088 19.3 0.0 0.0019 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain FYVE_2 PF02318.16 KND88725.1 - 0.0024 18.1 0.9 0.0063 16.7 0.9 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger AAA_7 PF12775.7 KND88725.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 KND88725.1 - 0.0037 16.5 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KND88725.1 - 0.0061 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KND88725.1 - 0.0078 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Prok-RING_1 PF14446.6 KND88725.1 - 0.0098 15.8 3.5 0.0098 15.8 3.5 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 1 AAA_5 PF07728.14 KND88725.1 - 0.03 14.3 0.1 0.11 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KND88725.1 - 0.032 13.7 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 KND88725.1 - 0.035 14.6 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SMC_N PF02463.19 KND88725.1 - 0.037 13.4 0.0 0.084 12.3 0.0 1.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND88725.1 - 0.045 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain C1_1 PF00130.22 KND88725.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_helicase PF00910.22 KND88725.1 - 0.048 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KND88725.1 - 0.049 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KND88725.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 KND88725.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ATP-synt_ab PF00006.25 KND88725.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 KND88725.1 - 0.081 12.3 0.0 0.081 12.3 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KND88725.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND88725.1 - 0.11 12.7 0.0 0.32 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KND88725.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 KND88725.1 - 0.19 11.5 0.0 0.88 9.3 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KND88725.1 - 0.2 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit C1_2 PF03107.16 KND88725.1 - 0.42 11.0 6.3 0.22 11.9 3.1 2.1 2 0 0 2 2 2 0 C1 domain LtrA PF06772.11 KND88726.1 - 1.1e-07 31.4 38.7 3.4e-06 26.5 32.6 2.9 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Bystin PF05291.11 KND88727.1 - 2.8e-130 433.9 0.0 3.7e-130 433.5 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 KND88728.1 - 1.2e-65 220.7 0.0 5.5e-65 218.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KND88728.1 - 1.2e-22 79.5 2.7 2.3e-22 78.6 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.9 KND88728.1 - 0.0066 15.0 0.0 0.2 10.1 0.0 2.3 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 KND88728.1 - 0.048 14.1 0.2 0.73 10.3 0.0 2.8 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 KND88728.1 - 0.12 12.7 0.0 1.4 9.4 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat WD40 PF00400.32 KND88729.1 - 2.9e-12 46.9 1.4 0.026 15.4 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88729.1 - 0.0038 17.5 0.0 9.3 6.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 KND88730.1 - 1.2e-60 205.2 0.0 2.9e-60 203.9 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family Peptidase_S26 PF10502.9 KND88731.1 - 0.0062 16.3 0.1 0.58 10.0 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KND88731.1 - 0.06 13.3 0.0 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase S24-like EIF_2_alpha PF07541.12 KND88732.1 - 2.8e-37 127.3 0.0 5.5e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KND88732.1 - 1.3e-13 51.1 0.7 2.8e-13 50.0 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain ArfGap PF01412.18 KND88734.1 - 1.5e-35 121.8 0.2 3.1e-35 120.8 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.26 KND88735.1 - 2.7e-07 30.6 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND88735.1 - 0.0014 18.5 0.0 0.0073 16.2 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KND88735.1 - 0.0028 18.7 0.0 0.0058 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KND88735.1 - 0.011 15.6 0.1 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Methyltr_RsmB-F PF01189.17 KND88736.1 - 1.3e-32 113.1 0.0 4.5e-25 88.5 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KND88736.1 - 0.073 13.2 0.0 0.33 11.0 0.0 2.1 2 1 0 2 2 2 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 KND88737.1 - 3.2e-41 140.5 0.7 2.2e-30 105.3 2.7 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KND88737.1 - 7.2e-23 80.8 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND88737.1 - 2.4e-06 27.2 0.0 5.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KND88737.1 - 0.0023 17.0 0.0 0.49 9.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 KND88737.1 - 0.063 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 KND88737.1 - 0.13 11.7 0.0 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family EzrA PF06160.12 KND88739.1 - 1.8e-05 23.1 15.1 1.8e-05 23.1 15.1 2.6 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 KND88739.1 - 0.00015 21.9 7.0 0.00015 21.9 7.0 5.7 4 1 2 6 6 6 2 ABC transporter C-terminal domain CorA PF01544.18 KND88739.1 - 0.04 13.2 7.2 0.092 12.0 7.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4239 PF14023.6 KND88739.1 - 0.47 10.2 7.0 0.2 11.3 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.12 KND88739.1 - 1.5 8.8 5.2 3.7 7.6 0.3 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb5_C PF01191.19 KND88740.1 - 2e-32 110.8 0.2 1.4e-31 108.2 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KND88740.1 - 1.1e-25 90.1 0.0 1.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KND88740.1 - 0.057 13.4 0.0 0.22 11.6 0.0 1.9 3 0 0 3 3 3 0 Restriction endonuclease COX2_TM PF02790.15 KND88741.1 - 9.7 6.4 9.5 0.098 12.8 0.6 2.3 3 1 1 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain TFCD_C PF12612.8 KND88742.1 - 6.9e-29 101.0 0.1 1.8e-28 99.7 0.1 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KND88742.1 - 0.005 17.2 5.6 0.32 11.4 0.2 4.7 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KND88742.1 - 0.01 16.0 6.2 2.7 8.5 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat IFRD PF05004.13 KND88742.1 - 0.11 11.6 1.3 0.28 10.2 0.6 2.0 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Glyco_hydro_76 PF03663.14 KND88743.1 - 7.5e-44 150.7 11.3 1.8e-43 149.5 11.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND88743.1 - 1.8e-06 27.3 0.2 0.078 12.0 0.0 4.0 2 1 2 4 4 4 4 Glycosyl Hydrolase Family 88 SH3_9 PF14604.6 KND88744.1 - 4.6e-10 39.2 0.1 5.9e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KND88744.1 - 1.3 8.7 3.3 2.3 7.9 2.5 1.8 2 0 0 2 2 2 0 SH3 domain IML1 PF12257.8 KND88745.1 - 4.5e-34 117.9 0.7 6.4e-34 117.4 0.7 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 IML1 PF12257.8 KND88746.1 - 1.3e-70 237.7 0.0 1.8e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KND88746.1 - 2.9e-22 78.5 0.0 7.1e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.16 KND88747.1 - 3.6e-29 101.8 27.3 3.6e-29 101.8 27.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cation_efflux PF01545.21 KND88748.1 - 7.4e-49 166.2 2.5 9.5e-49 165.8 2.5 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KND88748.1 - 9.7e-05 21.7 0.2 0.00015 21.1 0.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter FAM176 PF14851.6 KND88748.1 - 0.098 12.3 0.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 KND88748.1 - 0.18 12.1 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Iso_dh PF00180.20 KND88750.1 - 3.2e-79 266.6 0.0 2.1e-50 171.8 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase AAA_18 PF13238.6 KND88751.1 - 0.00021 21.8 0.0 0.0024 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KND88751.1 - 0.0011 19.1 0.0 0.0031 17.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KND88751.1 - 0.0024 17.2 0.0 0.0085 15.4 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 KND88751.1 - 0.0076 16.6 0.1 0.011 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KND88751.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KND88751.1 - 0.054 14.0 0.0 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KND88751.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KND88751.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 KND88751.1 - 0.14 12.2 0.0 0.55 10.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain GSCFA PF08885.11 KND88751.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 GSCFA family FNIP_N PF14636.6 KND88752.1 - 7.2e-43 147.2 0.3 7.2e-43 147.2 0.3 3.8 2 1 0 2 2 2 1 Folliculin-interacting protein N-terminus RHH_1 PF01402.21 KND88752.1 - 0.17 11.9 1.2 6.3 6.9 0.1 3.5 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DEAD PF00270.29 KND88753.1 - 8.4e-48 162.4 0.0 1.1e-46 158.8 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND88753.1 - 2e-25 89.3 0.0 2.9e-23 82.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KND88753.1 - 4.3e-21 74.9 2.7 1.2e-20 73.4 2.7 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KND88753.1 - 3e-07 30.6 0.0 8.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ_C PF01556.18 KND88754.1 - 1.2e-38 132.6 0.0 1.6e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND88754.1 - 3.3e-23 81.6 1.7 6.5e-23 80.6 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND88754.1 - 1.1e-09 38.5 19.7 2.5e-09 37.3 19.7 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KND88754.1 - 0.0095 15.9 13.6 0.11 12.5 2.5 2.8 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DnaJ PF00226.31 KND88755.1 - 5.7e-14 52.0 0.7 5.7e-14 52.0 0.7 2.3 3 0 0 3 3 3 1 DnaJ domain Xpo1 PF08389.12 KND88756.1 - 4.3e-24 85.3 0.0 1.6e-22 80.1 0.0 3.6 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KND88756.1 - 1.8e-06 27.8 0.0 7e-06 25.9 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 KND88756.1 - 0.002 18.1 0.0 0.25 11.4 0.0 3.0 2 0 0 2 2 2 1 Importin 13 repeat Adaptin_N PF01602.20 KND88756.1 - 0.0047 15.6 0.3 0.19 10.2 0.1 2.6 2 0 0 2 2 2 1 Adaptin N terminal region RRM_1 PF00076.22 KND88757.1 - 3.8e-22 77.9 0.0 4.3e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 KND88758.1 - 2e-48 164.9 0.0 2.7e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KND88758.1 - 2.1e-20 73.4 0.0 3.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MOR2-PAG1_N PF14222.6 KND88759.1 - 4.3e-221 735.6 0.0 1.4e-220 734.0 0.0 1.8 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KND88759.1 - 7.3e-90 301.2 0.0 3e-89 299.2 0.0 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KND88759.1 - 2e-35 121.8 3.9 4e-19 67.8 0.1 3.5 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_EZ PF13513.6 KND88759.1 - 0.0073 16.8 0.6 0.52 10.9 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 KND88759.1 - 0.059 13.8 3.7 1.5 9.2 0.1 4.9 8 0 0 8 8 8 0 HEAT repeats HEAT PF02985.22 KND88759.1 - 0.18 12.1 2.6 2.8 8.4 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat RPN1_RPN2_N PF17781.1 KND88761.1 - 1.2e-110 369.8 6.1 2.1e-110 369.0 5.9 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KND88761.1 - 2e-29 101.4 0.0 3.5e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KND88761.1 - 4e-21 74.3 15.1 1.1e-06 28.8 0.2 8.9 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KND88761.1 - 8.3e-09 35.7 0.4 0.0022 18.3 0.0 4.0 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.22 KND88761.1 - 0.032 14.5 0.0 22 5.7 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat RIO1 PF01163.22 KND88762.1 - 1.4e-40 138.9 0.2 1.3e-39 135.7 0.2 2.1 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KND88762.1 - 2.7e-32 110.8 0.1 4.8e-32 110.0 0.1 1.4 1 0 0 1 1 1 1 Rio2, N-terminal Kdo PF06293.14 KND88762.1 - 6.1e-07 29.0 0.0 5.5e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88762.1 - 3e-06 27.4 0.3 0.021 14.8 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family NOA36 PF06524.12 KND88762.1 - 0.046 13.0 12.9 0.069 12.5 12.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 KND88762.1 - 0.065 13.3 5.9 0.12 12.4 5.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 KND88762.1 - 0.17 10.0 17.0 0.23 9.5 17.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 KND88762.1 - 0.37 10.2 13.3 0.58 9.5 13.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 KND88762.1 - 0.39 10.7 8.0 0.49 10.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KND88762.1 - 0.42 8.8 13.8 0.55 8.4 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.19 KND88762.1 - 0.59 10.8 15.2 1.1 9.9 15.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.18 KND88762.1 - 1.1 9.1 5.3 1.7 8.4 5.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region BUD22 PF09073.10 KND88762.1 - 1.2 8.4 12.7 1.7 7.9 12.1 1.4 2 0 0 2 2 2 0 BUD22 DUF5523 PF17661.1 KND88762.1 - 1.9 8.1 8.4 3.2 7.4 8.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) RNA_pol_3_Rpc31 PF11705.8 KND88762.1 - 1.9 8.7 19.2 4.3 7.5 19.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 KND88762.1 - 1.9 8.8 6.2 3.3 8.0 6.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.11 KND88762.1 - 2 7.9 10.5 3 7.4 10.5 1.2 1 0 0 1 1 1 0 PPP4R2 Nop53 PF07767.11 KND88762.1 - 2.3 7.5 13.2 3.7 6.8 13.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RPN2_C PF18004.1 KND88762.1 - 4.3 7.2 6.3 7.5 6.5 6.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pox_Ag35 PF03286.14 KND88762.1 - 5.2 6.8 9.1 10 5.9 9.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 KND88762.1 - 8 6.1 14.3 12 5.5 14.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 KND88762.1 - 8.1 5.5 22.7 11 5.0 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.13 KND88762.1 - 8.4 5.3 9.8 13 4.7 9.8 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 KND88762.1 - 8.8 4.5 12.6 12 4.0 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CLASP_N PF12348.8 KND88763.1 - 3.8e-133 442.1 0.0 2.3e-89 298.9 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 KND88763.1 - 0.00046 20.2 0.0 2.6 8.6 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat DUF4704 PF15787.5 KND88763.1 - 0.0088 15.3 0.3 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Cnd1 PF12717.7 KND88763.1 - 0.024 14.7 0.0 4 7.5 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND88763.1 - 0.14 12.6 4.8 3.5 8.1 0.0 4.2 4 1 0 4 4 4 0 HEAT repeats RhoGAP PF00620.27 KND88764.1 - 9.7e-45 152.1 0.0 9.7e-45 152.1 0.0 2.3 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 KND88764.1 - 2.1e-13 50.3 16.6 4.2e-09 36.5 1.5 2.4 2 0 0 2 2 2 2 LIM domain Desulfoferrod_N PF06397.12 KND88764.1 - 0.037 13.6 7.9 5.8 6.6 0.7 3.6 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain zf-ribbon_3 PF13248.6 KND88764.1 - 0.45 10.0 12.2 0.78 9.2 0.0 3.9 4 1 0 4 4 4 0 zinc-ribbon domain Fez1 PF06818.15 KND88764.1 - 1.8 9.0 14.7 5.2 7.5 14.7 1.7 1 0 0 1 1 1 0 Fez1 Zn-ribbon_8 PF09723.10 KND88764.1 - 6.8 6.9 18.4 1.5 9.0 1.1 4.0 3 1 1 4 4 4 0 Zinc ribbon domain Cytochrom_CIII PF02085.16 KND88764.1 - 7 7.1 8.5 20 5.6 8.5 1.7 1 0 0 1 1 1 0 Class III cytochrome C family zf-CHY PF05495.12 KND88764.1 - 9.5 6.8 15.0 12 6.4 5.3 2.7 1 1 0 2 2 2 0 CHY zinc finger DUF4210 PF13915.6 KND88765.1 - 2.2e-33 114.7 0.1 6.6e-33 113.1 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 KND88765.1 - 4.1e-24 84.5 0.2 8.1e-24 83.5 0.2 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.6 KND88766.1 - 3.1e-14 52.9 1.3 0.023 14.9 0.0 7.0 5 2 2 7 7 7 3 PPR repeat family PPR PF01535.20 KND88766.1 - 3.9e-11 42.4 6.9 0.072 13.4 0.0 7.9 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KND88766.1 - 6.9e-06 25.7 0.0 1.9 8.3 0.1 4.3 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 KND88766.1 - 0.00012 21.6 1.1 0.17 11.2 0.8 2.9 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 KND88766.1 - 0.00022 21.2 0.7 0.1 12.7 0.0 4.2 4 1 2 6 6 6 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 KND88766.1 - 0.018 15.6 14.4 0.82 10.2 0.0 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND88766.1 - 0.081 13.1 1.1 5.9 7.1 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Suf PF05843.14 KND88766.1 - 0.11 12.4 0.3 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KND88766.1 - 0.52 11.3 15.1 50 5.1 0.0 8.6 9 1 1 10 10 10 0 Tetratricopeptide repeat rRNA_processing PF08524.11 KND88767.1 - 7.8e-05 22.7 34.8 0.0086 16.1 34.8 2.1 1 1 0 1 1 1 1 rRNA processing Nop53 PF07767.11 KND88767.1 - 6 6.1 36.6 8.4 5.7 36.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 KND88768.1 - 6.1e-05 22.5 0.1 0.047 13.0 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND88768.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3435 PF11917.8 KND88769.1 - 9.8e-40 136.7 0.0 1.2e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TPR_10 PF13374.6 KND88770.1 - 1.9e-20 72.0 2.3 2.2e-09 36.9 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND88770.1 - 5.2e-14 52.3 0.4 1.9e-05 24.8 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND88770.1 - 8.3e-09 34.9 3.0 0.0016 18.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND88770.1 - 9.5e-07 28.4 4.7 0.0012 18.8 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND88770.1 - 3.1e-05 23.8 1.9 0.14 12.4 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND88770.1 - 4.4e-05 23.3 7.7 0.042 14.0 0.1 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND88770.1 - 8.7e-05 23.0 0.2 0.037 14.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND88770.1 - 0.00085 19.9 4.4 0.0091 16.6 0.6 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KND88770.1 - 0.018 14.4 0.0 3.6 6.8 0.0 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_4 PF07721.14 KND88770.1 - 0.019 15.6 0.8 2.8 8.8 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KND88770.1 - 0.025 14.3 4.2 3.1 7.6 0.1 3.7 3 0 0 3 3 3 0 TPR repeat TPR_21 PF09976.9 KND88770.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KND88770.1 - 0.31 11.8 2.4 21 6.0 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF3435 PF11917.8 KND88772.1 - 0.026 13.5 1.3 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) ComGF PF15980.5 KND88772.1 - 0.084 13.2 1.7 0.14 12.5 1.7 1.3 1 0 0 1 1 1 0 Putative Competence protein ComGF Mito_carr PF00153.27 KND88773.1 - 1.1e-61 204.7 2.0 9.1e-23 80.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND88773.1 - 0.16 11.1 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease MT-A70 PF05063.14 KND88774.1 - 2.1e-30 105.9 0.0 2.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Ribosomal_L23 PF00276.20 KND88775.1 - 8.1e-11 42.1 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 LtuB PF17455.2 KND88775.1 - 0.039 14.6 0.2 0.068 13.8 0.2 1.4 1 0 0 1 1 1 0 Late transcription unit B HTH_17 PF12728.7 KND88775.1 - 0.061 13.5 0.3 19 5.5 0.1 2.9 2 1 1 3 3 3 0 Helix-turn-helix domain SLATT_fungal PF18142.1 KND88776.1 - 3.3e-30 104.5 0.0 4.5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DrsE PF02635.15 KND88777.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 DsrE/DsrF-like family Spo7 PF03907.13 KND88778.1 - 1.4e-92 309.2 0.0 1.9e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KND88779.1 - 7.9e-21 74.9 0.0 4.4e-20 72.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND88779.1 - 4.6e-14 53.5 0.5 4.6e-14 53.5 0.5 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND88779.1 - 8.3e-14 51.4 0.0 2.8e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KND88779.1 - 5.2e-06 26.0 0.0 9.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KND88779.1 - 0.00032 20.4 0.0 0.00088 19.0 0.0 1.7 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 KND88779.1 - 0.0083 16.0 0.8 0.16 11.8 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 KND88779.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 KND88779.1 - 0.086 12.5 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 KND88779.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 KND88779.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family NDT80_PhoG PF05224.12 KND88780.1 - 1.8e-41 142.4 0.0 3.4e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ABC_tran PF00005.27 KND88782.1 - 6.2e-45 153.1 1.9 6.7e-22 78.5 0.0 3.5 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 KND88782.1 - 7.9e-12 45.6 7.0 1.2e-06 28.6 1.3 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND88782.1 - 3.2e-09 36.6 6.8 0.04 13.4 0.1 4.9 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND88782.1 - 5e-08 32.6 0.7 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KND88782.1 - 1.6e-07 31.7 0.7 0.00017 21.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran_Xtn PF12848.7 KND88782.1 - 3.2e-07 30.3 4.9 3.2e-07 30.3 4.9 2.2 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KND88782.1 - 1.7e-06 28.1 1.7 0.095 12.8 0.1 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 KND88782.1 - 1.1e-05 26.0 0.1 0.19 12.3 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KND88782.1 - 1.2e-05 25.5 2.4 0.23 11.6 0.1 3.9 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KND88782.1 - 2.2e-05 24.9 4.7 0.13 12.7 2.6 2.9 2 1 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 KND88782.1 - 2.9e-05 23.2 2.1 0.087 11.8 0.2 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 KND88782.1 - 5.1e-05 23.6 0.5 0.27 11.5 0.0 3.5 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KND88782.1 - 0.00011 22.1 2.6 0.15 11.9 0.0 3.3 4 0 0 4 4 3 2 RsgA GTPase AAA PF00004.29 KND88782.1 - 0.00014 22.3 0.1 0.029 14.8 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KND88782.1 - 0.00016 21.6 0.0 0.061 13.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 KND88782.1 - 0.00026 20.8 1.2 0.19 11.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 KND88782.1 - 0.00033 20.6 0.1 3.2 7.6 0.0 3.5 3 0 0 3 3 3 1 NTPase AAA_23 PF13476.6 KND88782.1 - 0.00082 19.9 22.7 0.04 14.4 6.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_24 PF13479.6 KND88782.1 - 0.0036 17.1 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 KND88782.1 - 0.0038 17.4 11.3 0.14 12.2 0.3 3.8 3 1 1 4 4 4 2 Helicase HerA, central domain AAA_14 PF13173.6 KND88782.1 - 0.0052 16.8 0.1 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KND88782.1 - 0.0061 16.6 0.2 0.56 10.2 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 KND88782.1 - 0.0093 15.6 0.5 0.21 11.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.25 KND88782.1 - 0.0098 15.6 0.1 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 KND88782.1 - 0.013 15.2 7.4 0.061 13.0 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 KND88782.1 - 0.016 15.6 0.1 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 KND88782.1 - 0.018 14.8 0.1 2.2 7.9 0.0 2.8 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 KND88782.1 - 0.019 14.6 0.8 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KND88782.1 - 0.02 14.8 0.1 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 KND88782.1 - 0.021 14.0 2.4 0.87 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) MobB PF03205.14 KND88782.1 - 0.025 14.5 0.2 9.4 6.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 KND88782.1 - 0.033 13.6 0.3 1.2 8.6 0.1 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 KND88782.1 - 0.038 13.3 0.2 7.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KND88782.1 - 0.045 14.0 0.5 19 5.5 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Vfa1 PF08432.10 KND88782.1 - 0.05 13.9 0.5 0.12 12.7 0.5 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_7 PF12775.7 KND88782.1 - 0.053 13.0 0.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 KND88782.1 - 0.1 12.6 0.6 2.4 8.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 KND88782.1 - 0.2 11.7 4.9 2.7 8.0 0.0 2.9 3 1 0 3 3 2 0 Dynamin family Thymidylate_kin PF02223.17 KND88782.1 - 0.24 11.0 3.4 3.8 7.1 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase ABC_ATPase PF09818.9 KND88782.1 - 0.29 9.9 0.0 0.29 9.9 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 KND88782.1 - 0.46 9.6 9.0 1.6 7.9 0.0 3.4 4 0 0 4 4 3 0 NB-ARC domain AAA_17 PF13207.6 KND88782.1 - 0.64 10.5 8.7 5.2 7.5 0.1 3.7 4 0 0 4 4 3 0 AAA domain TRM PF02005.16 KND88783.1 - 5.6e-102 341.7 0.0 8.5e-91 304.9 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DAGK_cat PF00781.24 KND88783.1 - 1.4e-06 28.0 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Rep_4 PF05797.11 KND88783.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) NMO PF03060.15 KND88784.1 - 4.5e-55 187.3 1.5 6e-55 186.9 1.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND88784.1 - 6.2e-11 41.9 3.3 1.1e-10 41.1 3.3 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND88784.1 - 0.00049 19.2 4.5 0.00084 18.5 4.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KND88784.1 - 0.0077 15.5 0.4 0.012 14.8 0.4 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Pterin_bind PF00809.22 KND88785.1 - 4e-79 265.7 0.0 5.8e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KND88785.1 - 4.3e-36 123.8 0.0 8.4e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BIR PF00653.21 KND88786.1 - 3.7e-45 152.4 3.8 2.7e-21 76.0 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.15 KND88786.1 - 0.043 13.9 0.0 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 BED zinc finger Snf7 PF03357.21 KND88786.1 - 0.075 12.6 1.8 4.3 6.9 0.2 2.5 2 0 0 2 2 2 0 Snf7 DUF333 PF03891.15 KND88787.1 - 0.074 13.3 0.3 1 9.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF333) DIOX_N PF14226.6 KND88788.1 - 6.4e-22 78.5 0.0 1.1e-21 77.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND88788.1 - 3.2e-20 72.5 0.0 6.9e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Svf1_C PF17187.4 KND88789.1 - 5.6e-64 214.9 0.0 1.2e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KND88789.1 - 1.7e-52 177.8 0.0 2.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Mit_KHE1 PF10173.9 KND88790.1 - 1.6e-60 204.5 0.1 2.3e-60 204.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Utp21 PF04192.12 KND88791.1 - 2.8e-81 272.5 0.1 4.5e-81 271.8 0.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 KND88791.1 - 3.8e-17 62.4 20.5 9.4e-07 29.4 0.4 8.7 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88791.1 - 4e-12 46.3 0.0 0.04 14.2 0.0 6.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND88791.1 - 1.1e-07 30.9 0.0 0.079 11.6 0.0 3.4 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KND88791.1 - 1.4e-07 30.4 0.0 2.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 KND88791.1 - 0.0018 17.1 0.0 1.3 7.7 0.0 2.3 1 1 1 2 2 2 2 Nup133 N terminal like PALB2_WD40 PF16756.5 KND88791.1 - 0.035 13.0 0.0 5.3 5.9 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain His_Phos_2 PF00328.22 KND88792.1 - 1e-107 360.9 0.1 1.5e-107 360.3 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KND88792.1 - 2e-36 124.0 0.1 3.9e-36 123.1 0.1 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KND88792.1 - 2.8e-05 23.8 0.0 5.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain FmdA_AmdA PF03069.15 KND88793.1 - 2.5e-52 178.0 0.0 4e-31 108.2 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family Acetyltransf_1 PF00583.25 KND88795.1 - 0.00056 20.1 0.0 0.00095 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GATA PF00320.27 KND88796.1 - 2.2e-14 52.8 2.6 4.3e-14 51.8 2.6 1.5 1 0 0 1 1 1 1 GATA zinc finger Atg14 PF10186.9 KND88796.1 - 0.004 16.3 11.3 0.004 16.3 11.3 2.2 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KND88796.1 - 0.0085 16.6 13.5 0.0085 16.6 13.5 2.7 3 0 0 3 3 3 1 Apg6 coiled-coil region DUF4226 PF10774.9 KND88796.1 - 0.014 15.7 4.7 0.014 15.7 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) ArfGap PF01412.18 KND88796.1 - 0.028 14.5 1.0 0.047 13.8 0.1 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Golgin_A5 PF09787.9 KND88796.1 - 0.079 12.4 17.9 0.47 9.9 8.7 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF3138 PF11336.8 KND88796.1 - 0.43 9.1 8.1 0.22 10.1 4.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) Macoilin PF09726.9 KND88796.1 - 0.98 7.9 15.0 1.3 7.4 15.0 1.1 1 0 0 1 1 1 0 Macoilin family FPP PF05911.11 KND88796.1 - 1.2 7.2 17.5 0.077 11.2 11.0 1.7 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil FAP206 PF12018.8 KND88796.1 - 2.8 7.4 8.3 1.3 8.5 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function GAS PF13851.6 KND88796.1 - 2.9 7.2 20.4 0.047 13.0 10.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.9 KND88796.1 - 3.9 6.2 14.4 0.14 11.0 7.1 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.11 KND88796.1 - 4.4 6.1 21.9 0.97 8.3 12.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 KND88796.1 - 5.3 7.1 25.2 0.4 10.8 14.7 2.5 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 KND88796.1 - 7.8 5.0 11.0 0.26 9.8 4.7 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A T3SSipB PF16535.5 KND88796.1 - 8.9 6.8 18.5 11 6.5 4.2 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB HEAT_2 PF13646.6 KND88797.1 - 1.4e-26 92.7 6.0 6.6e-13 48.9 0.2 3.9 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 KND88797.1 - 5.4e-20 70.0 5.1 0.0031 18.0 0.0 7.0 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KND88797.1 - 3.2e-09 36.2 2.9 0.19 12.1 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 KND88797.1 - 0.042 13.9 0.1 6.3 6.8 0.0 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KND88797.1 - 0.046 14.2 9.4 1.3 9.6 0.1 4.9 2 2 3 5 5 5 0 HEAT-like repeat MFS_1 PF07690.16 KND88798.1 - 2.8e-15 56.1 46.5 4.5e-07 29.1 16.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 KND88798.1 - 9.7e-05 21.0 12.0 0.00016 20.2 12.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 KND88799.1 - 3.1e-63 213.3 0.6 4.7e-63 212.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND88799.1 - 4.1e-10 39.6 5.5 0.00027 21.2 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND88799.1 - 0.0029 18.3 12.1 0.083 13.8 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND88799.1 - 0.19 12.2 10.2 1.4 9.5 2.1 4.2 3 0 0 3 3 3 0 Zinc-finger double domain SAP30_Sin3_bdg PF13867.6 KND88800.1 - 1.3e-08 35.0 1.6 2e-07 31.3 0.2 2.2 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 GMC_oxred_N PF00732.19 KND88801.1 - 6.5e-31 107.8 0.0 4.6e-29 101.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND88801.1 - 4.2e-30 105.2 0.0 1.3e-29 103.6 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KND88801.1 - 0.00018 20.9 0.0 0.00068 19.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND88801.1 - 0.00072 18.7 0.1 0.0035 16.5 0.0 2.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 KND88801.1 - 0.011 15.1 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND88801.1 - 0.03 13.9 0.3 1.5 8.3 0.3 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND88801.1 - 0.032 14.5 0.2 0.082 13.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain WW PF00397.26 KND88801.1 - 0.078 13.1 0.2 0.27 11.3 0.2 2.0 1 0 0 1 1 1 0 WW domain FAD_binding_3 PF01494.19 KND88801.1 - 0.083 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KND88801.1 - 0.085 11.5 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pex2_Pex12 PF04757.14 KND88802.1 - 3.1e-52 177.4 5.5 4.1e-52 177.0 5.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region WSC PF01822.19 KND88803.1 - 3.9e-12 46.2 8.8 1.1e-11 44.7 8.8 1.8 1 0 0 1 1 1 1 WSC domain 4HBT PF03061.22 KND88805.1 - 4.9e-14 52.4 0.0 7.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KND88805.1 - 0.0072 16.5 0.0 0.0094 16.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 KND88805.1 - 0.053 13.8 0.1 0.1 12.8 0.0 1.5 2 0 0 2 2 2 0 Thioesterase-like superfamily Metallophos PF00149.28 KND88806.1 - 1.5e-13 51.7 0.6 2.4e-13 51.0 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND88806.1 - 7e-06 26.3 2.3 8.4e-05 22.8 2.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.12 KND88807.1 - 2e-106 356.6 12.9 2.4e-106 356.3 12.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ParA PF10609.9 KND88808.1 - 1.1e-95 319.8 0.0 1.2e-95 319.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KND88808.1 - 1.4e-07 31.6 0.0 4.3e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KND88808.1 - 8.3e-05 22.6 0.0 0.00037 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KND88808.1 - 0.00022 20.5 0.2 0.0011 18.2 0.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KND88808.1 - 0.00033 20.2 0.0 0.72 9.2 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 KND88808.1 - 0.0054 16.3 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KND88808.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_26 PF13500.6 KND88808.1 - 0.0098 15.7 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 KND88808.1 - 0.013 15.5 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TF_Zn_Ribbon PF08271.12 KND88808.1 - 0.019 14.5 0.1 0.045 13.3 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding MipZ PF09140.11 KND88808.1 - 0.036 13.3 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 ATPase MipZ T2SSE PF00437.20 KND88808.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 KND88808.1 - 0.099 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CLP1_P PF16575.5 KND88808.1 - 0.099 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KND88808.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 KND88808.1 - 0.14 12.6 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KND88808.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KND88808.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 KND88808.1 - 0.24 10.8 0.0 2.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TFIIS_C PF01096.18 KND88809.1 - 7e-13 48.2 0.7 7e-13 48.2 0.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KND88809.1 - 1.1e-05 25.1 3.2 1.1e-05 25.1 3.2 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 KND88809.1 - 0.0058 16.5 2.3 0.0058 16.5 2.3 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3268 PF11672.8 KND88809.1 - 4.2 7.7 8.0 2.7 8.3 1.9 2.7 1 1 2 3 3 3 0 zinc-finger-containing domain Zn-ribbon_8 PF09723.10 KND88809.1 - 6.4 7.0 10.5 6.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 KND88809.1 - 6.7 6.7 15.9 2.5 8.1 0.3 3.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Nipped-B_C PF12830.7 KND88810.1 - 5.5e-48 163.4 1.2 8.8e-47 159.5 0.1 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KND88810.1 - 4.3e-07 30.1 2.2 1.9e-06 28.0 0.7 2.9 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KND88810.1 - 0.00014 21.8 1.7 0.43 11.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KND88810.1 - 0.0024 17.9 0.1 0.051 13.6 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KND88810.1 - 0.054 12.1 0.1 1.4 7.4 0.0 3.1 3 1 0 3 3 3 0 Adaptin N terminal region P_C PF06640.11 KND88810.1 - 0.95 9.6 9.2 1.5 8.9 0.0 2.9 2 0 0 2 2 2 0 P protein C-terminus Ras PF00071.22 KND88812.1 - 4.6e-56 188.9 0.1 7e-56 188.3 0.1 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KND88812.1 - 5.7e-19 68.5 0.0 8.9e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND88812.1 - 2.6e-06 27.0 0.0 1.2e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND88812.1 - 1.2e-05 25.0 0.2 6.2e-05 22.6 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KND88812.1 - 0.00029 20.8 0.1 0.86 9.5 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KND88812.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KND88812.1 - 0.0073 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KND88812.1 - 0.038 13.8 0.9 1.3 8.8 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 KND88813.1 - 6.4e-35 119.9 0.0 1.1e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 KND88814.1 - 1.7e-17 63.4 0.0 2.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Na_Ca_ex PF01699.24 KND88816.1 - 1.8e-42 144.8 34.3 3.5e-21 75.7 13.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PPV_E1_N PF00524.18 KND88816.1 - 0.051 14.0 0.4 0.083 13.3 0.4 1.3 1 0 0 1 1 1 0 E1 Protein, N terminal domain DUF2034 PF10356.9 KND88818.1 - 7.6e-31 107.0 0.0 1.1e-16 60.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KND88818.1 - 2.5e-08 33.9 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Lon_C PF05362.13 KND88819.1 - 2.1e-64 216.9 0.0 3.5e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KND88819.1 - 2.4e-32 112.5 0.0 4.4e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KND88819.1 - 2e-21 76.8 0.0 4.8e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 KND88819.1 - 8.8e-07 28.8 0.0 2.7e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 KND88819.1 - 1.5e-06 28.3 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND88819.1 - 4.6e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KND88819.1 - 4.4e-05 23.8 0.0 0.00058 20.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KND88819.1 - 9e-05 21.5 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KND88819.1 - 0.00011 22.0 0.1 0.00067 19.4 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND88819.1 - 0.00052 20.5 1.3 0.0021 18.5 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KND88819.1 - 0.0091 15.7 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 KND88819.1 - 0.015 15.8 0.4 0.08 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KND88819.1 - 0.026 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNTTIP1_dimer PF18192.1 KND88819.1 - 0.041 14.2 0.2 1.7 9.0 0.1 2.9 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain RNA_helicase PF00910.22 KND88819.1 - 0.046 14.1 0.0 0.18 12.2 0.0 2.1 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 KND88819.1 - 0.058 13.3 0.2 0.16 11.9 0.0 1.8 2 0 0 2 2 1 0 RsgA GTPase AAA_7 PF12775.7 KND88819.1 - 0.12 11.9 0.7 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 KND88819.1 - 0.5 10.9 3.4 0.88 10.1 0.0 2.7 3 0 0 3 3 3 0 ABC transporter EOS1 PF12326.8 KND88820.1 - 0.21 11.5 0.8 0.26 11.2 0.8 1.1 1 0 0 1 1 1 0 N-glycosylation protein tRNA-synt_1c PF00749.21 KND88820.1 - 0.28 10.0 5.9 0.039 12.9 1.9 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain FAM176 PF14851.6 KND88820.1 - 1.8 8.2 6.1 11 5.7 2.7 2.1 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 KND88820.1 - 2.7 6.6 8.0 3.5 6.3 8.0 1.1 1 0 0 1 1 1 0 Presenilin AIM3 PF17096.5 KND88820.1 - 4.4 8.3 15.2 5.1 8.1 4.5 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RTA1 PF04479.13 KND88821.1 - 1e-11 44.8 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Pkinase PF00069.25 KND88822.1 - 1.6e-10 40.8 0.1 1.2e-09 37.9 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88822.1 - 1.4e-09 37.6 0.0 2.2e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RTA1 PF04479.13 KND88824.1 - 2e-28 99.4 10.9 2.8e-28 98.9 10.9 1.1 1 0 0 1 1 1 1 RTA1 like protein BSP PF04450.12 KND88825.1 - 1.6e-74 250.2 0.0 1.8e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria 5-FTHF_cyc-lig PF01812.20 KND88828.1 - 1.3e-28 100.1 0.0 2e-28 99.5 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family OPT PF03169.15 KND88829.1 - 1.4e-202 674.7 40.3 1.7e-202 674.4 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1453 PF07301.11 KND88829.1 - 0.014 15.4 0.5 0.05 13.6 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Pkinase PF00069.25 KND88831.1 - 8.3e-61 205.7 0.0 8.4e-60 202.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88831.1 - 2.3e-26 92.6 0.0 1.9e-25 89.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KND88831.1 - 4.2e-17 62.7 0.8 2e-08 34.7 0.2 3.3 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 KND88831.1 - 1.6e-05 24.4 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KND88831.1 - 0.0033 16.4 0.3 0.0057 15.6 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain DUF2336 PF10098.9 KND88831.1 - 0.027 14.0 0.1 0.027 14.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) RIO1 PF01163.22 KND88831.1 - 0.065 12.8 0.3 0.19 11.3 0.1 1.7 1 1 1 2 2 2 0 RIO1 family YukC PF10140.9 KND88831.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC UBA_2 PF08587.11 KND88831.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Yippee-Mis18 PF03226.14 KND88833.1 - 1.3e-19 70.3 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rsm1 PF08600.10 KND88833.1 - 0.048 13.8 0.2 0.093 12.9 0.2 1.5 1 0 0 1 1 1 0 Rsm1-like RIG-I_C-RD PF11648.8 KND88833.1 - 0.11 12.7 1.4 0.41 10.9 0.1 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I CHAT PF12770.7 KND88835.1 - 4e-10 39.6 0.5 7.2e-10 38.7 0.5 1.3 1 0 0 1 1 1 1 CHAT domain NACHT PF05729.12 KND88835.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_2 PF02230.16 KND88836.1 - 1.5e-58 198.2 0.0 2.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KND88836.1 - 1.1e-08 34.6 1.6 0.00021 20.6 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KND88836.1 - 1.3e-05 25.2 0.2 0.069 13.0 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KND88836.1 - 1.7e-05 24.6 0.5 0.43 10.2 0.1 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold FSH1 PF03959.13 KND88836.1 - 2.7e-05 24.0 0.0 4.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 KND88836.1 - 6.4e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KND88836.1 - 7.2e-05 23.5 0.1 0.00012 22.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 KND88836.1 - 0.00024 20.4 0.0 0.62 9.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 KND88836.1 - 0.00074 19.0 0.7 0.043 13.3 0.0 2.5 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 KND88836.1 - 0.031 14.4 0.0 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein DUF2974 PF11187.8 KND88836.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_M20 PF01546.28 KND88837.1 - 5.2e-33 114.5 0.0 7.5e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND88837.1 - 3.8e-12 46.1 0.0 6.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SRAP PF02586.14 KND88838.1 - 1.3e-75 253.7 0.0 2.3e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) SRAP PF02586.14 KND88839.1 - 2e-81 272.7 0.0 2.9e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) GLEYA PF10528.9 KND88842.1 - 3.2e-18 65.9 0.5 6.6e-18 64.9 0.5 1.6 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KND88842.1 - 0.00047 20.0 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 PA14 domain Trehalase PF01204.18 KND88843.1 - 3.6e-191 636.4 0.0 4.3e-191 636.2 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KND88843.1 - 4.5e-18 64.7 0.5 7.6e-18 63.9 0.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF58 PF01882.18 KND88843.1 - 0.094 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF58 ICL PF00463.21 KND88844.1 - 2e-290 963.8 0.4 2.3e-290 963.6 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KND88844.1 - 1.1e-10 41.4 4.3 1.4e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DNA_pol_E_B PF04042.16 KND88845.1 - 3.6e-61 206.2 0.0 5.1e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.16 KND88846.1 - 1.4e-25 90.0 29.4 4.2e-15 55.5 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND88846.1 - 3e-08 32.9 9.6 0.00015 20.8 0.6 2.2 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KND88846.1 - 0.00042 19.3 16.3 0.0012 17.8 10.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KND88846.1 - 0.0025 16.3 3.5 0.0025 16.3 3.5 2.3 2 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) RNA_pol_Rpb1_1 PF04997.12 KND88847.1 - 1.3e-79 267.8 0.0 2.5e-79 266.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KND88847.1 - 8.2e-77 258.2 0.1 1.3e-76 257.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KND88847.1 - 8.6e-72 240.8 0.0 1.6e-71 239.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KND88847.1 - 6.1e-37 127.0 0.0 1.4e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KND88847.1 - 2.2e-30 104.8 0.1 5.1e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DDHD PF02862.17 KND88848.1 - 9.6e-63 212.3 0.0 9.6e-63 212.3 0.0 3.1 2 1 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 KND88848.1 - 0.061 12.9 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Adhesin_P1_N PF18652.1 KND88848.1 - 0.75 9.8 5.1 0.71 9.9 3.2 1.9 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain zf-RING_2 PF13639.6 KND88849.1 - 0.0039 17.5 1.7 0.0039 17.5 1.7 1.8 2 0 0 2 2 2 1 Ring finger domain Ank_2 PF12796.7 KND88849.1 - 0.025 15.2 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) LexA_DNA_bind PF01726.16 KND88849.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Cys_rich_CPXG PF14255.6 KND88849.1 - 0.35 10.8 2.6 0.56 10.1 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG UPF0547 PF10571.9 KND88849.1 - 4.1 7.6 7.0 0.72 10.0 1.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CH PF00307.31 KND88850.1 - 4e-68 226.5 0.0 4.4e-18 65.4 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KND88850.1 - 3e-05 24.4 0.5 0.00039 20.8 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KND88850.1 - 0.027 14.0 0.6 6.8 6.5 0.2 3.3 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 KND88850.1 - 0.88 9.7 3.4 6.4 7.0 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain RRM_1 PF00076.22 KND88853.1 - 1.8e-11 43.7 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND88853.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_60s PF00428.19 KND88855.1 - 2.6 8.7 17.7 66 4.2 17.7 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein Fungal_trans PF04082.18 KND88856.1 - 2.4e-13 49.7 1.6 4.2e-13 49.0 1.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND88856.1 - 0.003 17.9 3.2 0.0044 17.4 0.6 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type RRM_1 PF00076.22 KND88857.1 - 2e-35 120.4 0.5 1.5e-16 59.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND88857.1 - 1.8e-10 40.8 1.6 0.0005 20.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KND88857.1 - 5.8e-06 26.2 0.1 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.6 KND88857.1 - 0.029 14.2 0.2 13 5.7 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4651) RRM_3 PF08777.11 KND88857.1 - 0.043 13.9 0.3 9.8 6.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif TFIIA PF03153.13 KND88857.1 - 0.94 9.4 16.7 1.3 9.0 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.18 KND88858.1 - 3.5e-49 167.4 0.0 6.5e-49 166.5 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_90 PF05686.12 KND88859.1 - 3.2e-15 56.0 3.4 4.7e-13 48.8 0.0 2.5 3 0 0 3 3 3 2 Glycosyl transferase family 90 RRM_1 PF00076.22 KND88861.1 - 9.8e-17 60.5 0.0 1.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NPV_P10 PF05531.12 KND88861.1 - 0.017 15.6 0.3 0.031 14.7 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Nup35_RRM_2 PF14605.6 KND88861.1 - 0.038 14.0 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spc7 PF08317.11 KND88861.1 - 0.067 12.1 2.2 0.092 11.6 2.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.24 KND88861.1 - 0.069 13.1 0.4 0.096 12.6 0.4 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD RRM_occluded PF16842.5 KND88861.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif DivIC PF04977.15 KND88861.1 - 0.13 12.1 5.3 0.2 11.4 5.3 1.2 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.19 KND88861.1 - 0.17 9.8 0.3 0.2 9.5 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GPS2_interact PF15784.5 KND88861.1 - 0.21 12.1 2.9 0.34 11.4 2.9 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain ZapB PF06005.12 KND88861.1 - 0.26 11.7 4.5 0.42 11.1 4.5 1.2 1 0 0 1 1 1 0 Cell division protein ZapB WD40_alt PF14077.6 KND88861.1 - 0.34 10.8 1.9 2 8.4 0.7 2.2 1 1 1 2 2 2 0 Alternative WD40 repeat motif GRP PF07172.11 KND88861.1 - 3.6 8.3 13.2 0.11 13.2 7.0 1.7 2 0 0 2 2 2 0 Glycine rich protein family cNMP_binding PF00027.29 KND88862.1 - 5.7e-39 132.1 0.0 3e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 KND88863.1 - 2.7e-53 180.7 4.6 3.6e-53 180.3 4.6 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) HABP4_PAI-RBP1 PF04774.15 KND88864.1 - 0.021 15.6 0.3 0.031 15.1 0.3 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SoxE PF06525.11 KND88865.1 - 0.056 12.9 0.0 0.062 12.8 0.0 1.0 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain CDT1_C PF16679.5 KND88866.1 - 1.3e-22 80.0 0.0 1.3e-22 80.0 0.0 3.0 4 0 0 4 4 4 1 DNA replication factor Cdt1 C-terminal domain GCP_C_terminal PF04130.13 KND88868.1 - 1.1e-101 340.4 0.0 2.3e-101 339.3 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KND88868.1 - 2.3e-83 280.3 0.0 6.8e-83 278.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal SAGA-Tad1 PF12767.7 KND88869.1 - 1.4e-59 201.7 0.0 1.8e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SH2_2 PF14633.6 KND88870.1 - 5.5e-83 277.6 0.0 1.4e-82 276.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KND88870.1 - 9.7e-41 138.8 0.7 3.2e-40 137.1 0.7 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 KND88870.1 - 1.1e-32 112.8 0.0 1.2e-31 109.6 0.0 2.6 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KND88870.1 - 5.2e-32 110.3 0.0 1.2e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 KND88870.1 - 2.2e-21 76.2 27.1 2.2e-21 76.2 27.1 7.1 4 1 1 6 6 4 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KND88870.1 - 6.7e-07 30.1 1.1 1.6e-05 25.7 1.1 3.3 1 1 0 1 1 1 1 HHH domain S1 PF00575.23 KND88870.1 - 4.6e-06 26.9 0.0 1.1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 KND88870.1 - 1.3e-05 25.2 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 KND88870.1 - 2.7e-05 24.3 0.0 9.1e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 KND88870.1 - 0.035 14.6 0.0 0.099 13.1 0.0 1.8 1 1 0 1 1 1 0 Tex protein YqgF-like domain B12-binding PF02310.19 KND88870.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain NUDIX PF00293.28 KND88871.1 - 3.8e-14 52.8 0.3 5.5e-14 52.3 0.3 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 KND88871.1 - 0.0035 17.3 0.2 0.0074 16.3 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain DUF92 PF01940.16 KND88872.1 - 1.4e-87 293.0 2.5 1.7e-87 292.7 2.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 ADIP PF11559.8 KND88873.1 - 3.6e-36 124.5 7.2 3.6e-36 124.5 7.2 2.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding RRP7 PF12923.7 KND88873.1 - 7.4e-28 97.1 13.7 7.4e-28 97.1 13.7 2.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KND88873.1 - 3.4e-14 53.0 0.0 7.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Golgin_A5 PF09787.9 KND88873.1 - 0.002 17.7 1.9 0.002 17.7 1.9 3.1 4 0 0 4 4 4 1 Golgin subfamily A member 5 BAR PF03114.18 KND88875.1 - 2.7e-67 226.9 6.5 3.4e-67 226.6 6.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KND88875.1 - 8.4e-16 57.3 0.1 2e-15 56.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND88875.1 - 3.3e-12 46.1 0.1 5.6e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND88875.1 - 2.8e-10 39.7 0.9 8.4e-10 38.2 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain TMPIT PF07851.13 KND88875.1 - 0.088 12.0 3.0 1.7 7.8 0.0 2.2 1 1 1 2 2 2 0 TMPIT-like protein Vps5 PF09325.10 KND88875.1 - 0.42 10.1 6.9 2 7.9 2.1 2.3 2 0 0 2 2 2 0 Vps5 C terminal like GTP_EFTU PF00009.27 KND88876.1 - 2e-49 167.8 0.0 3.3e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KND88876.1 - 2.2e-44 150.0 2.7 3.8e-44 149.2 2.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KND88876.1 - 1e-16 60.7 0.0 1.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND88876.1 - 4e-06 27.1 0.3 1.3e-05 25.5 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND88876.1 - 4e-05 23.7 0.0 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KND88876.1 - 0.00019 21.1 0.0 0.0058 16.2 0.0 2.4 3 0 0 3 3 3 1 Ras family EFG_II PF14492.6 KND88876.1 - 0.00071 19.6 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 KND88876.1 - 0.034 14.4 0.1 1.9 8.7 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND88876.1 - 0.088 12.2 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RF3_C PF16658.5 KND88876.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KND88876.1 - 0.22 11.7 2.4 0.45 10.7 2.4 1.4 1 0 0 1 1 1 0 Snurportin1 MIT PF04212.18 KND88877.1 - 9.7e-13 48.0 0.4 1.7e-12 47.2 0.4 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DHquinase_I PF01487.15 KND88878.1 - 4.2e-22 79.5 0.0 6.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase DHquinase_I PF01487.15 KND88879.1 - 1e-10 42.3 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Glyoxalase PF00903.25 KND88880.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KND88880.1 - 0.059 14.2 0.0 0.27 12.1 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Mpp10 PF04006.12 KND88882.1 - 4.3e-107 359.1 51.1 1.8e-106 357.0 51.1 1.8 1 1 0 1 1 1 1 Mpp10 protein SHNi-TPR PF10516.9 KND88883.1 - 1.3e-11 43.7 0.0 3.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 KND88883.1 - 0.0014 18.6 2.7 0.53 10.5 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND88883.1 - 0.0045 17.2 2.3 0.077 13.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND88883.1 - 0.23 12.2 4.1 0.65 10.7 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat AMPK1_CBM PF16561.5 KND88886.1 - 0.00064 19.9 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase zf-RING_UBOX PF13445.6 KND88887.1 - 5.5e-08 32.7 4.1 5.8e-08 32.6 1.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KND88887.1 - 8.1e-08 32.0 4.4 1.5e-07 31.1 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND88887.1 - 7.2e-07 29.1 3.0 1.4e-06 28.1 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND88887.1 - 7.2e-07 29.4 4.7 1.8e-06 28.2 4.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND88887.1 - 7.8e-07 28.9 4.8 1.8e-06 27.7 4.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND88887.1 - 3.2e-06 26.9 5.7 9.1e-06 25.4 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND88887.1 - 5.3e-06 26.5 1.0 5.3e-06 26.5 1.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KND88887.1 - 0.004 17.0 1.4 0.0074 16.1 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 KND88887.1 - 0.0086 15.9 10.8 0.091 12.6 10.4 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KND88887.1 - 0.069 13.3 3.0 0.054 13.6 1.1 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Phage-Gp8 PF09215.10 KND88887.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4, Gp8 zf-rbx1 PF12678.7 KND88887.1 - 0.17 12.2 4.3 0.51 10.7 4.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 KND88887.1 - 0.37 10.6 4.6 1.6 8.6 4.5 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger TerY_C PF15616.6 KND88887.1 - 1.2 9.2 3.9 3 7.9 3.9 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain Lar_restr_allev PF14354.6 KND88887.1 - 7.9 7.0 6.3 1.8 9.0 1.1 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Fungal_trans PF04082.18 KND88888.1 - 2.4e-24 85.8 0.2 3.8e-24 85.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88888.1 - 0.033 14.3 11.7 0.064 13.4 11.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_114 PF03537.13 KND88889.1 - 3.3e-82 275.3 0.0 4e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Chorismate_synt PF01264.21 KND88889.1 - 1.2 7.8 3.2 1.8 7.2 3.2 1.2 1 0 0 1 1 1 0 Chorismate synthase Sulfotransfer_4 PF17784.1 KND88890.1 - 1.2e-57 195.2 0.1 1.7e-54 184.9 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KND88890.1 - 0.012 16.0 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family LIP PF03583.14 KND88891.1 - 4.2e-77 259.3 0.1 6e-77 258.8 0.1 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KND88891.1 - 0.015 14.8 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 KND88892.1 - 3.6e-36 124.8 16.9 7.3e-36 123.8 16.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.8 KND88892.1 - 0.036 14.3 3.9 1.8 8.9 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Phage_holin_5_2 PF16079.5 KND88892.1 - 1.4 9.3 13.3 3.3 8.1 0.0 5.0 4 1 2 6 6 6 0 Phage holin family Hol44, in holin superfamily V Toxin_GhoT_OrtT PF10753.9 KND88892.1 - 2.1 8.6 7.7 18 5.6 0.3 3.8 4 0 0 4 4 4 0 Toxin GhoT_OrtT RTA1 PF04479.13 KND88894.1 - 5.7e-33 114.3 8.4 7.9e-33 113.8 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein T5orf172 PF10544.9 KND88895.1 - 1.8e-16 60.5 0.9 4.6e-16 59.2 0.9 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KND88895.1 - 2e-07 31.6 1.7 4.6e-07 30.4 1.7 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Nre_C PF04895.12 KND88895.1 - 0.05 13.5 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Archaeal Nre, C-terminal Arrestin_N PF00339.29 KND88896.1 - 4e-14 52.9 0.0 4.8e-10 39.7 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF2465 PF10239.9 KND88897.1 - 0.11 11.7 0.2 0.13 11.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) PGAP1 PF07819.13 KND88898.1 - 1.9e-05 24.5 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KND88898.1 - 6.4e-05 22.6 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KND88898.1 - 0.00014 22.6 2.7 0.00025 21.7 2.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 KND88898.1 - 0.00019 21.4 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 KND88898.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KND88898.1 - 0.057 13.0 0.2 0.36 10.4 0.2 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_MOT1 PF16983.5 KND88899.1 - 4.4e-62 207.4 33.0 8.6e-36 122.7 8.4 3.1 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Ribosomal_L5e PF17144.4 KND88900.1 - 4.4e-79 264.2 0.3 7.4e-79 263.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KND88900.1 - 1.5e-34 118.8 9.5 1.5e-34 118.8 9.5 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KND88900.1 - 0.025 15.0 0.1 0.025 15.0 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SAM_2 PF07647.17 KND88901.1 - 8.8e-11 41.8 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KND88901.1 - 5e-10 39.1 0.1 1.2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 KND88901.1 - 1e-08 35.6 0.0 3.8e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 KND88901.1 - 2.3e-08 33.5 0.1 5.6e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND88901.1 - 0.004 16.8 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 KND88901.1 - 0.01 16.2 0.2 0.024 15.0 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short_C2 PF13561.6 KND88903.1 - 1.6e-49 168.6 0.2 1.2e-44 152.7 0.2 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND88903.1 - 7.2e-37 126.7 0.6 1.1e-27 96.8 0.0 2.1 1 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KND88903.1 - 1.6e-06 28.1 2.5 6.1e-06 26.3 2.5 1.8 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KND88903.1 - 0.044 13.1 0.0 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MR_MLE_C PF13378.6 KND88904.1 - 6e-44 150.2 0.0 8.4e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KND88904.1 - 1.9e-10 41.0 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.15 KND88904.1 - 0.16 11.3 0.0 0.67 9.2 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase CFEM PF05730.11 KND88905.1 - 3.2e-07 30.3 6.3 8e-07 29.1 6.3 1.6 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 KND88905.1 - 0.00026 20.4 2.8 0.00087 18.7 2.8 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Apt1 PF10351.9 KND88905.1 - 0.029 13.3 2.8 0.03 13.2 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 KND88905.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rifin Podoplanin PF05808.11 KND88905.1 - 0.2 11.7 22.6 0.48 10.5 22.6 1.6 1 1 0 1 1 1 0 Podoplanin SPX PF03105.19 KND88905.1 - 0.24 11.3 6.2 0.28 11.1 6.2 1.1 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 KND88905.1 - 6.1 7.2 14.9 15 5.9 15.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_L22 PF00237.19 KND88906.1 - 2e-22 79.4 0.0 3.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HA2 PF04408.23 KND88907.1 - 5.4e-15 55.6 0.1 5.4e-15 55.6 0.1 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KND88907.1 - 1.4e-12 47.9 0.0 3.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND88907.1 - 4.1e-12 46.2 0.1 8.8e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KND88907.1 - 2.2e-08 34.4 0.0 5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KND88907.1 - 5.2e-08 33.2 0.7 2.8e-07 30.9 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KND88907.1 - 0.0056 17.0 0.1 0.014 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KND88907.1 - 0.02 15.4 0.0 0.061 13.8 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KND88907.1 - 0.033 14.7 2.7 0.71 10.4 1.8 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KND88907.1 - 0.054 13.9 2.4 0.21 12.0 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 KND88907.1 - 0.089 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 KND88907.1 - 0.14 12.0 0.0 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase RRM_1 PF00076.22 KND88908.1 - 8e-46 153.7 0.1 3.6e-18 65.1 0.4 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND88908.1 - 5.3e-33 112.7 0.0 6.6e-27 93.2 0.0 3.7 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KND88908.1 - 1.3e-13 50.7 0.0 0.0012 18.8 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KND88908.1 - 6.3e-09 35.8 0.1 0.00011 22.1 0.2 3.9 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 KND88908.1 - 0.00029 20.4 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KND88908.1 - 0.0012 18.8 0.0 0.92 9.5 0.0 3.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KND88908.1 - 0.0037 17.4 0.0 16 5.7 0.0 4.2 5 0 0 5 5 5 1 RNA recognition motif TPR_14 PF13428.6 KND88908.1 - 0.041 14.7 0.8 3.6 8.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_6 PF13344.6 KND88909.1 - 2e-20 72.7 0.0 3.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND88909.1 - 5.5e-13 48.8 0.1 3.7e-12 46.1 0.0 2.5 4 0 0 4 4 4 1 HAD-hyrolase-like Hydrolase PF00702.26 KND88909.1 - 0.085 13.1 0.0 6.6 7.0 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase MTBP_C PF14920.6 KND88909.1 - 0.24 11.1 2.4 0.4 10.4 2.4 1.3 1 0 0 1 1 1 0 MDM2-binding Mitochondr_Som1 PF11093.8 KND88912.1 - 1.4e-26 92.3 0.1 1.6e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Pkinase PF00069.25 KND88913.1 - 1.1e-08 34.8 0.0 1.4e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND88913.1 - 1.7e-06 27.5 0.0 7.5e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND88913.1 - 2.3e-05 24.4 0.1 0.17 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KND88913.1 - 6.1e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KND88913.1 - 0.0012 17.7 0.1 0.0017 17.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KND88913.1 - 0.0018 17.6 0.0 0.0024 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Aldo_ket_red PF00248.21 KND88914.1 - 2.2e-07 30.4 0.0 3.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KND88915.1 - 3.2e-51 173.0 1.2 3.7e-51 172.8 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.16 KND88917.1 - 1.8e-06 27.2 8.0 2.1e-06 26.9 8.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CsbD PF05532.12 KND88918.1 - 8.4e-18 64.0 23.9 9.5e-13 47.8 2.4 4.0 2 1 1 3 3 3 3 CsbD-like Aminotran_5 PF00266.19 KND88919.1 - 4.7e-91 305.5 0.0 5.7e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND88919.1 - 9.4e-07 28.4 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KND88919.1 - 1.2e-06 28.1 0.1 4.7e-06 26.2 0.1 1.9 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KND88919.1 - 0.0057 15.4 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 KND88919.1 - 0.0059 15.2 0.0 0.0087 14.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CMD PF02627.20 KND88921.1 - 9.6e-10 38.4 0.1 3.5e-08 33.4 0.1 2.4 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PRMT5_C PF17286.2 KND88921.1 - 0.19 11.6 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Oxidored_q6 PF01058.22 KND88922.1 - 4e-22 78.4 0.0 6.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.25 KND88923.1 - 2e-95 319.8 0.0 2.5e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KND88923.1 - 5e-34 116.0 24.4 6e-13 48.6 6.3 3.9 4 0 0 4 4 4 3 WW domain Mito_carr PF00153.27 KND88924.1 - 3.2e-73 241.7 2.8 3.3e-24 84.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND88924.1 - 1.6e-05 24.2 0.2 0.0066 15.6 0.0 3.1 3 1 1 4 4 4 2 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 KND88925.1 - 4.1e-90 300.2 3.3 4.6e-90 300.0 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KND88925.1 - 0.016 15.9 0.5 0.016 15.9 0.5 2.4 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MOSC PF03473.17 KND88926.1 - 2.1e-26 92.5 0.0 2.1e-24 86.0 0.0 2.5 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 KND88926.1 - 5.5e-12 45.5 0.3 1.1e-11 44.5 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 KND88926.1 - 1.9e-09 37.3 0.1 3.6e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 KND88926.1 - 4.3e-07 30.6 0.0 2.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KND88926.1 - 0.068 13.3 0.6 1.2 9.3 0.3 2.2 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Gln-synt_C PF00120.24 KND88927.1 - 1.7e-16 60.2 0.0 4.8e-12 45.5 0.0 2.4 3 0 0 3 3 3 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KND88927.1 - 6.2e-10 38.7 0.0 2.3e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Acetyltransf_3 PF13302.7 KND88928.1 - 1.9e-19 70.7 0.0 2.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND88928.1 - 0.00078 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PEP-utilizers_C PF02896.18 KND88928.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain MMADHC PF10229.9 KND88929.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein ArsA_ATPase PF02374.15 KND88930.1 - 1.4e-99 333.2 0.0 1.8e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 KND88930.1 - 5.2e-12 45.9 0.0 9.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KND88930.1 - 1.1e-11 45.0 0.0 6.5e-11 42.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Acetyltransf_3 PF13302.7 KND88930.1 - 1e-08 36.0 0.0 2.4e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_NifH PF00142.18 KND88930.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Acetyltransf_1 PF00583.25 KND88930.1 - 4.2e-05 23.8 0.0 8.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ParA PF10609.9 KND88930.1 - 8.5e-05 22.1 0.1 0.00051 19.6 0.0 2.1 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 KND88930.1 - 0.00012 21.7 0.0 0.00056 19.5 0.0 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 KND88930.1 - 0.00067 19.3 0.0 0.0046 16.6 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 KND88930.1 - 0.021 15.2 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KND88930.1 - 0.036 13.7 0.1 0.065 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KND88930.1 - 0.069 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 KND88930.1 - 0.25 11.9 0.8 0.53 10.8 0.0 2.1 3 0 0 3 3 2 0 AAA domain TRP_2 PF08344.11 KND88930.1 - 0.4 10.9 2.2 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 Transient receptor ion channel II DWNN PF08783.11 KND88931.1 - 1.6e-29 102.0 0.1 2.9e-29 101.2 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KND88931.1 - 5.9e-09 35.6 6.8 2e-08 33.9 6.2 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KND88931.1 - 0.0017 18.1 10.0 0.0017 18.1 10.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC PF00098.23 KND88931.1 - 0.0034 17.4 1.1 0.0062 16.6 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 KND88931.1 - 0.007 16.7 7.3 0.015 15.6 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 KND88931.1 - 0.011 15.8 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 0 U-box domain FYVE_2 PF02318.16 KND88931.1 - 0.016 15.4 2.7 0.016 15.4 2.7 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_6 PF14835.6 KND88931.1 - 0.043 13.7 2.5 0.083 12.8 2.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KND88931.1 - 0.14 11.9 6.4 0.31 10.9 6.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 KND88931.1 - 0.2 11.7 14.1 0.024 14.6 8.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KND88931.1 - 0.67 9.9 11.0 1.3 9.0 11.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND88931.1 - 1.8 8.8 9.6 6.2 7.1 9.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KND88931.1 - 1.8 8.5 8.4 1.8 8.4 6.8 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF4588 PF15251.6 KND88932.1 - 6.2e-07 29.4 0.2 7.9e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.13 KND88932.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Hairy Orange Ion_trans PF00520.31 KND88933.1 - 3.4e-07 29.7 2.6 5.8e-07 29.0 2.7 1.3 1 1 0 1 1 1 1 Ion transport protein CCDC106 PF15794.5 KND88933.1 - 0.0062 16.3 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 106 Herpes_BLRF2 PF05812.12 KND88933.1 - 0.055 13.6 0.5 0.16 12.1 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein bZIP_1 PF00170.21 KND88933.1 - 0.075 13.1 0.5 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor SNF2_N PF00176.23 KND88936.1 - 7.4e-75 251.8 0.0 1.4e-74 250.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KND88936.1 - 1.6e-42 144.1 3.5 1.6e-42 144.1 3.5 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KND88936.1 - 1e-35 122.8 3.5 1e-35 122.8 3.5 3.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 KND88936.1 - 1.7e-18 67.0 0.2 7.9e-18 64.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND88936.1 - 3e-10 40.3 0.0 2.8e-09 37.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KND88936.1 - 1.3e-05 24.5 0.0 6.4e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KND88936.1 - 0.00097 18.9 0.0 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KND88936.1 - 0.0036 17.0 0.0 0.015 15.0 0.0 2.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 KND88936.1 - 0.04 14.1 0.0 18 5.6 0.0 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain NYD-SP28_assoc PF14775.6 KND88936.1 - 0.076 13.1 3.3 0.18 11.9 2.1 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain DEAD_2 PF06733.15 KND88936.1 - 0.086 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 KND88936.1 - 0.094 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain CSD PF00313.22 KND88937.1 - 1.1e-28 98.8 0.5 1.2e-28 98.7 0.5 1.0 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 KND88937.1 - 0.0014 18.3 0.5 0.002 17.8 0.5 1.3 1 0 0 1 1 1 1 Ribonuclease B OB domain CusF_Ec PF11604.8 KND88937.1 - 0.018 15.0 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF WD40 PF00400.32 KND88938.1 - 3.4e-20 72.0 1.9 2.7e-07 31.2 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88938.1 - 5.8e-13 49.0 0.0 0.079 13.3 0.0 5.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND88938.1 - 0.00044 19.7 0.0 0.026 13.8 0.0 2.4 1 1 0 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 KND88938.1 - 0.011 14.8 0.0 0.081 12.0 0.0 1.8 1 1 0 2 2 2 0 Coatomer WD associated region Nup160 PF11715.8 KND88938.1 - 0.051 12.2 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KND88938.1 - 0.13 11.1 0.3 7.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain p450 PF00067.22 KND88939.1 - 4.3e-50 170.8 0.0 8.5e-37 127.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Rho_N PF07498.12 KND88939.1 - 0.013 15.4 0.9 0.031 14.2 0.9 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain FTHFS PF01268.19 KND88940.1 - 5.3e-251 833.7 0.1 7.2e-251 833.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KND88940.1 - 4.2e-67 224.5 0.7 4.2e-67 224.5 0.7 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KND88940.1 - 1.3e-26 93.1 0.4 1.8e-17 63.7 0.0 3.2 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain MFS_1 PF07690.16 KND88941.1 - 4.2e-43 147.6 33.1 4.2e-43 147.6 33.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND88941.1 - 1.8e-06 27.1 12.9 1.8e-06 27.1 12.9 2.2 2 1 0 3 3 3 1 Sugar (and other) transporter DUF4834 PF16118.5 KND88941.1 - 1 10.4 2.5 1.6 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) OATP PF03137.20 KND88941.1 - 1.7 6.8 6.5 0.55 8.5 1.4 2.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF3405 PF11885.8 KND88942.1 - 2.2e-201 670.0 0.1 2.2e-201 670.0 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) DUF445 PF04286.12 KND88942.1 - 0.047 13.5 7.3 0.083 12.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SKA1 PF07160.12 KND88942.1 - 0.96 9.2 12.2 1.6 8.5 12.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ARGLU PF15346.6 KND88942.1 - 8.5 6.2 31.3 18 5.2 31.3 1.4 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF676 PF05057.14 KND88943.1 - 4.8e-05 23.0 0.0 7.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KND88943.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FUSC_2 PF13515.6 KND88945.1 - 3.9e-27 94.9 6.8 3.9e-27 94.9 6.8 3.1 3 1 0 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 KND88945.1 - 5.2e-07 28.6 13.9 5.7e-07 28.5 4.2 3.6 4 0 0 4 4 4 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 KND88945.1 - 4.6e-05 22.6 1.2 9.1e-05 21.7 0.6 1.7 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 KND88945.1 - 0.023 13.5 13.5 0.74 8.6 7.4 3.6 3 1 0 3 3 3 0 Aluminium activated malate transporter ArAE_2 PF10334.9 KND88945.1 - 0.032 14.1 0.1 0.36 10.6 0.0 2.6 3 0 0 3 3 3 0 Aromatic acid exporter family member 2 Phage_holin_Dp1 PF16938.5 KND88945.1 - 0.15 12.3 1.6 1.3 9.3 0.0 3.3 4 0 0 4 4 4 0 Putative phage holin Dp-1 FUSC-like PF12805.7 KND88945.1 - 0.68 9.0 3.1 16 4.4 0.1 2.6 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS HAD_2 PF13419.6 KND88946.1 - 1.1e-11 45.2 0.0 2.1e-10 40.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND88946.1 - 6.5e-11 42.9 0.0 2.6e-07 31.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND88946.1 - 7.7e-07 29.1 0.3 1.3e-06 28.3 0.3 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KND88946.1 - 0.0011 19.5 0.1 0.034 14.6 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KND88946.1 - 0.0071 16.0 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Pkinase PF00069.25 KND88947.1 - 2.1e-65 220.7 0.0 2.8e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND88947.1 - 7.6e-39 133.6 0.0 9.7e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND88947.1 - 0.00032 19.6 0.0 0.00051 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KND88947.1 - 0.0013 18.2 0.0 0.0026 17.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KND88947.1 - 0.038 12.9 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 KND88947.1 - 0.093 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_2 PF12796.7 KND88949.1 - 6.2e-78 257.5 15.3 2.3e-16 60.1 0.2 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND88949.1 - 3.8e-56 186.4 1.9 3.9e-10 39.8 0.0 7.2 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88949.1 - 2.3e-55 178.0 0.0 4.1e-05 23.7 0.0 9.5 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 KND88949.1 - 6.7e-53 176.4 0.3 6.8e-11 42.5 0.0 9.2 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KND88949.1 - 7.4e-50 165.3 0.2 6.2e-06 26.4 0.0 9.8 10 0 0 10 10 10 9 Ankyrin repeat 3HCDH_RFF PF18321.1 KND88949.1 - 4.5e-05 23.8 7.3 21 5.6 0.0 7.2 6 3 1 7 7 7 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF2150 PF09920.9 KND88949.1 - 0.0019 18.2 12.0 0.7 9.8 0.3 4.9 3 1 3 6 6 6 2 Uncharacterized protein conserved in archaea (DUF2150) Zeta_toxin PF06414.12 KND88949.1 - 0.0021 17.3 0.7 6.3 6.0 0.0 4.5 3 3 2 5 5 5 1 Zeta toxin RisS_PPD PF16524.5 KND88949.1 - 0.017 15.4 1.0 51 4.2 0.0 4.2 3 1 1 4 4 4 0 Periplasmic domain of Sensor histidine kinase RisS HEM4 PF02602.15 KND88949.1 - 0.023 14.1 4.5 11 5.2 0.1 4.5 2 1 1 4 4 4 0 Uroporphyrinogen-III synthase HemD Resolvase PF00239.21 KND88949.1 - 0.37 10.9 5.6 2.2 8.4 0.2 3.7 1 1 2 4 4 4 0 Resolvase, N terminal domain Ank_2 PF12796.7 KND88950.1 - 3.4e-36 123.7 0.0 1.3e-13 51.4 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND88950.1 - 3.8e-31 107.0 0.1 4.3e-09 36.7 0.0 4.4 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND88950.1 - 1.1e-30 105.3 0.9 2.6e-07 30.8 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND88950.1 - 3.3e-29 97.7 0.0 0.0007 19.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KND88950.1 - 3e-27 93.8 0.1 0.00013 22.3 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat FUSC_2 PF13515.6 KND88952.1 - 3.7e-25 88.5 4.6 3.7e-25 88.5 4.6 3.5 3 1 0 3 3 3 1 Fusaric acid resistance protein-like Phage_holin_Dp1 PF16938.5 KND88952.1 - 0.00095 19.3 1.0 0.053 13.7 0.1 3.3 2 0 0 2 2 2 1 Putative phage holin Dp-1 FUSC PF04632.12 KND88952.1 - 7.7 4.9 32.5 0.014 14.0 1.7 4.3 4 1 0 4 4 4 0 Fusaric acid resistance protein family NAD_binding_6 PF08030.12 KND88953.1 - 5.9e-21 75.2 0.0 8.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KND88953.1 - 4.6e-15 55.9 10.9 7.2e-15 55.2 10.9 1.3 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND88953.1 - 4.1e-07 30.1 0.0 9.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KND88953.1 - 0.089 13.4 0.0 0.61 10.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3817 PF12823.7 KND88953.1 - 5.9 7.8 11.4 2.5 9.0 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) AA_permease_2 PF13520.6 KND88954.1 - 2e-55 188.4 45.5 2.5e-55 188.1 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND88954.1 - 8.6e-19 67.5 35.0 1.2e-18 67.0 35.0 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_S8 PF00082.22 KND88955.1 - 3.5e-05 23.2 5.0 0.0078 15.5 0.0 2.7 2 1 1 3 3 3 2 Subtilase family DHO_dh PF01180.21 KND88956.1 - 4.9e-21 75.2 0.0 6.4e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Aim19 PF10315.9 KND88956.1 - 0.059 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 NMO PF03060.15 KND88956.1 - 0.21 10.9 4.5 0.33 10.3 4.5 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase MFS_1 PF07690.16 KND88957.1 - 2.5e-07 29.9 32.6 2.5e-07 29.9 32.6 4.3 2 2 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KND88959.1 - 2.7e-19 69.2 0.2 6.1e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND88959.1 - 5.5e-07 29.6 15.3 9.3e-07 28.9 15.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.12 KND88959.1 - 0.062 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Striatin family CCDC53 PF10152.9 KND88959.1 - 2.5 8.5 4.4 0.49 10.8 0.3 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Acetyltransf_10 PF13673.7 KND88961.1 - 5.3e-08 32.9 0.0 8.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND88961.1 - 6.7e-08 32.8 0.0 1.4e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND88961.1 - 1.3e-07 31.9 0.1 2.7e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND88961.1 - 0.0023 18.0 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF2235 PF09994.9 KND88962.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) SR-25 PF10500.9 KND88963.1 - 0.26 10.9 24.3 0.27 10.8 8.1 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GAGA_bind PF06217.12 KND88963.1 - 5.3 7.2 13.7 8 6.6 2.5 2.7 3 0 0 3 3 3 0 GAGA binding protein-like family HAD_2 PF13419.6 KND88964.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND88964.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF913 PF06025.12 KND88964.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Forkhead PF00250.18 KND88965.1 - 8.6e-15 54.8 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KND88965.1 - 0.00031 21.0 0.1 0.00065 20.0 0.1 1.6 1 0 0 1 1 1 1 FHA domain CTP_transf_like PF01467.26 KND88966.1 - 5.6e-29 101.2 0.0 9.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like PS_Dcarbxylase PF02666.15 KND88967.1 - 2.1e-52 177.6 0.0 3.3e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KND88967.1 - 8e-37 125.7 0.0 2.8e-17 62.9 0.0 3.0 3 0 0 3 3 3 2 C2 domain EF-hand_1 PF00036.32 KND88967.1 - 0.0032 16.9 0.0 0.009 15.5 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 KND88967.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 KND88967.1 - 0.06 13.3 0.7 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Ribosomal_L19e PF01280.20 KND88968.1 - 1.1e-58 197.4 7.7 2.1e-58 196.5 7.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.22 KND88968.1 - 1.5e-32 108.8 32.6 0.0051 17.0 0.1 20.6 22 0 0 22 22 21 8 HEAT repeat HEAT_EZ PF13513.6 KND88968.1 - 6.1e-31 106.4 54.6 1.1e-07 32.2 0.1 20.2 16 5 8 24 24 22 8 HEAT-like repeat HEAT_2 PF13646.6 KND88968.1 - 6.2e-26 90.6 44.7 2e-06 28.1 0.1 13.0 9 5 6 16 16 14 11 HEAT repeats Vac14_Fab1_bd PF12755.7 KND88968.1 - 5.9e-15 55.6 0.0 0.28 11.8 0.0 9.3 7 2 2 10 10 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KND88968.1 - 5.1e-12 46.1 11.4 0.58 10.2 0.2 9.5 5 2 3 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KND88968.1 - 1.3e-11 45.0 0.4 0.0002 21.5 0.0 5.8 4 1 1 5 5 5 2 Parkin co-regulated protein CLASP_N PF12348.8 KND88968.1 - 4.2e-09 36.3 0.0 0.55 9.8 0.0 5.7 4 1 1 6 6 6 3 CLASP N terminal UME PF08064.13 KND88968.1 - 5.3e-09 35.9 1.9 1.2 9.1 0.1 8.3 7 4 1 8 8 7 2 UME (NUC010) domain TIP120 PF08623.10 KND88968.1 - 1.2e-06 28.4 0.1 0.073 12.8 0.0 6.6 5 2 2 7 7 7 1 TATA-binding protein interacting (TIP20) Ecm29 PF13001.7 KND88968.1 - 2.3e-05 23.3 4.4 0.33 9.6 0.0 5.2 4 1 0 4 4 4 2 Proteasome stabiliser DUF3385 PF11865.8 KND88968.1 - 5.5e-05 23.1 0.1 4 7.3 0.0 6.6 5 2 0 5 5 5 1 Domain of unknown function (DUF3385) FANCI_S2 PF14676.6 KND88968.1 - 5.7e-05 23.5 0.5 0.28 11.5 0.1 3.8 3 0 0 3 3 3 2 FANCI solenoid 2 DUF937 PF06078.11 KND88968.1 - 0.00011 22.8 8.9 1.5 9.5 0.0 7.2 8 2 0 8 8 6 1 Bacterial protein of unknown function (DUF937) Tti2 PF10521.9 KND88968.1 - 0.00042 19.9 6.9 4.2 6.8 0.0 7.1 7 2 2 9 9 9 1 Tti2 family Ipi1_N PF12333.8 KND88968.1 - 0.014 16.0 0.2 0.87 10.2 0.0 3.9 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.8 KND88968.1 - 0.03 14.2 2.9 0.24 11.2 0.0 3.8 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal HEAT_PBS PF03130.16 KND88968.1 - 0.043 14.5 18.5 21 6.2 0.2 9.3 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat MMS19_C PF12460.8 KND88968.1 - 0.048 12.8 19.6 0.35 9.9 0.1 6.6 7 1 1 8 8 8 0 RNAPII transcription regulator C-terminal ADSL_C PF10397.9 KND88968.1 - 0.073 13.6 1.1 17 6.0 0.0 4.5 3 1 1 4 4 4 0 Adenylosuccinate lyase C-terminus RIX1 PF08167.12 KND88968.1 - 0.12 12.1 8.3 0.059 13.1 0.3 4.1 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis DUF3730 PF12530.8 KND88968.1 - 0.47 10.0 5.9 1.5 8.3 1.6 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) U3snoRNP10 PF12397.8 KND88968.1 - 0.94 9.8 8.2 68 3.9 0.1 5.9 6 0 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 SHMT PF00464.19 KND88969.1 - 1.3e-195 649.7 0.0 1.5e-195 649.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase FtsJ PF01728.19 KND88971.1 - 1.4e-28 100.1 0.0 1.7e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase B2 PF11473.8 KND88972.1 - 0.0058 16.4 0.3 0.31 10.9 0.0 2.7 2 0 0 2 2 2 1 RNA binding protein B2 Spc7 PF08317.11 KND88972.1 - 0.018 13.9 46.2 0.021 13.7 15.6 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KND88972.1 - 0.29 11.1 47.6 2.1 8.3 20.3 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KND88972.1 - 0.52 10.4 30.2 5.2 7.2 0.6 5.3 2 1 3 5 5 5 0 TolA binding protein trimerisation Scaffolding_pro PF11418.8 KND88972.1 - 0.8 10.3 8.6 0.78 10.3 0.2 3.4 3 0 0 3 3 3 0 Phi29 scaffolding protein Leu_zip PF15294.6 KND88972.1 - 2.3 7.7 47.4 0.016 14.7 16.4 3.1 2 1 2 4 4 4 0 Leucine zipper TPR_MLP1_2 PF07926.12 KND88972.1 - 2.6 8.1 55.1 0.14 12.2 8.4 5.0 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 KND88972.1 - 4 7.5 21.8 0.66 10.0 3.9 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 KND88972.1 - 9.4 5.6 50.6 0.015 14.8 14.4 3.6 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal CFEM PF05730.11 KND88973.1 - 2.9e-07 30.5 11.2 5.8e-07 29.5 11.2 1.5 1 0 0 1 1 1 1 CFEM domain Mid2 PF04478.12 KND88973.1 - 0.0078 16.1 0.1 0.0078 16.1 0.1 1.5 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4690 PF15756.5 KND88973.1 - 1.1 9.9 6.8 2.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Small Novel Rich in Cartilage WD40 PF00400.32 KND88974.1 - 1.1e-41 140.0 23.6 2.7e-08 34.3 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND88974.1 - 4.5e-09 36.5 0.3 0.088 13.1 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND88974.1 - 2e-05 23.5 8.4 0.015 14.0 0.1 4.5 1 1 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KND88974.1 - 0.03 13.7 0.1 0.54 9.5 0.0 2.2 2 1 0 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 KND88974.1 - 0.036 13.0 0.1 8.7 5.2 0.0 3.6 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KND88974.1 - 0.046 13.7 0.8 22 5.1 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat OST3_OST6 PF04756.13 KND88975.1 - 1.1e-91 307.3 0.0 1.4e-91 306.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4407 PF14362.6 KND88975.1 - 0.17 11.2 1.2 0.28 10.5 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CPBP PF02517.16 KND88975.1 - 1.6 9.1 6.2 6.8 7.1 6.2 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease 2OG-FeII_Oxy_2 PF13532.6 KND88976.1 - 2.9e-27 96.1 0.0 4.4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KND88976.1 - 1.3e-23 84.1 0.1 4.7e-23 82.2 0.1 2.1 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 KND88976.1 - 8.7e-05 22.5 0.4 0.00024 21.0 0.4 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Spore_coat_CotO PF14153.6 KND88976.1 - 0.14 12.1 1.2 0.29 11.0 1.2 1.5 1 0 0 1 1 1 0 Spore coat protein CotO TAF8_C PF10406.9 KND88977.1 - 1.1e-15 57.9 0.2 2.6e-15 56.7 0.2 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KND88977.1 - 5.4e-11 42.3 0.1 2.3e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Bromo_TP_like PF17027.5 KND88977.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Histone-fold protein FAD_binding_4 PF01565.23 KND88978.1 - 3e-14 52.9 1.6 6.7e-14 51.8 1.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND88978.1 - 3.3e-08 33.5 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like FACT-Spt16_Nlob PF14826.6 KND88979.1 - 8e-50 168.8 0.1 3.3e-49 166.8 0.1 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KND88979.1 - 1.7e-48 164.6 0.2 1.7e-48 164.6 0.2 3.7 3 1 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KND88979.1 - 6.3e-26 91.4 0.0 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KND88979.1 - 1.9e-15 57.0 1.2 3.3e-15 56.3 0.2 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC50 PF03381.15 KND88980.1 - 1.1e-101 340.0 0.0 1.4e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Trehalase_Ca-bi PF07492.11 KND88980.1 - 0.25 11.1 1.4 0.48 10.2 0.0 2.2 3 0 0 3 3 3 0 Neutral trehalase Ca2+ binding domain Transthyretin PF00576.21 KND88982.1 - 5.1e-38 130.1 0.0 6.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 KND88982.1 - 0.06 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 KND88982.1 - 0.079 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Zn_clus PF00172.18 KND88984.1 - 2.1e-05 24.6 8.4 3.7e-05 23.8 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 KND88984.1 - 0.33 10.1 9.7 0.64 9.2 9.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein SF1-HH PF16275.5 KND88985.1 - 3.8e-44 149.6 1.3 3.8e-44 149.6 1.3 1.9 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KND88985.1 - 6.8e-08 32.2 0.2 1.4e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 KH domain Peptidase_M28 PF04389.17 KND88986.1 - 1.2e-36 126.3 0.0 2.3e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KND88986.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 LIDHydrolase PF10230.9 KND88987.1 - 2.8e-41 141.9 0.0 3.5e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KND88987.1 - 0.00042 21.0 5.9 0.00053 20.7 5.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND88987.1 - 0.052 12.8 0.0 0.15 11.3 0.0 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 KND88988.1 - 1.2e-06 28.5 11.4 2.5e-06 27.5 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND88988.1 - 3.2e-05 23.1 0.3 6.9e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fmp27 PF10344.9 KND88989.1 - 1.9e-221 737.7 0.0 3e-221 737.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KND88989.1 - 5.7e-197 655.3 0.0 5.7e-197 655.3 0.0 3.5 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KND88989.1 - 7.7e-185 615.4 0.4 1.7e-184 614.2 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KND88989.1 - 1.2e-56 190.9 0.6 2.6e-56 189.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KND88989.1 - 3.1e-54 183.3 0.0 7.2e-54 182.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KND88989.1 - 2.7e-35 121.2 0.9 4.5e-34 117.3 0.1 3.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain CheZ PF04344.13 KND88989.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Ribosomal_S19e PF01090.19 KND88990.1 - 7.1e-57 190.9 0.1 8.6e-57 190.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF4449 PF14613.6 KND88991.1 - 3.7e-63 212.5 0.7 3.7e-63 212.5 0.7 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) GerPC PF10737.9 KND88991.1 - 0.049 13.7 3.5 0.15 12.1 3.5 1.8 1 0 0 1 1 1 0 Spore germination protein GerPC DUF3818 PF12825.7 KND88992.1 - 1.8e-43 148.9 0.0 7.5e-34 117.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KND88992.1 - 8.9e-43 145.4 0.0 2e-42 144.2 0.0 1.6 2 0 0 2 2 2 1 PX-associated TrkA_N PF02254.18 KND88992.1 - 0.14 12.4 3.0 2.1 8.6 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain Hanta_G1 PF01567.16 KND88993.1 - 0.0092 14.7 0.1 0.027 13.2 0.1 1.6 2 0 0 2 2 2 1 Hantavirus glycoprotein G1 CorA PF01544.18 KND88993.1 - 0.037 13.3 3.1 0.11 11.8 3.1 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein FtsX PF02687.21 KND88993.1 - 1 9.8 4.8 2 8.9 4.8 1.4 1 0 0 1 1 1 0 FtsX-like permease family Amidase PF01425.21 KND88994.1 - 7.2e-50 170.3 0.1 4.9e-49 167.5 0.1 2.0 1 1 1 2 2 2 1 Amidase MFS_1 PF07690.16 KND88995.1 - 2.2e-19 69.6 31.4 2.2e-19 69.6 31.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily CENP-B_N PF04218.13 KND88995.1 - 0.027 14.1 0.2 0.055 13.1 0.2 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain AlaE PF06610.13 KND88996.1 - 0.023 14.7 1.8 0.047 13.7 1.8 1.6 1 0 0 1 1 1 0 L-alanine exporter AC_N PF16214.5 KND88996.1 - 0.064 12.4 2.4 0.11 11.6 2.4 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region UL73_N PF12522.8 KND88996.1 - 1 9.1 9.9 2.5 7.9 9.9 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Zn_clus PF00172.18 KND88997.1 - 2.1e-06 27.7 7.3 4.1e-06 26.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND88997.1 - 6e-06 25.3 0.1 1.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ham1p_like PF01725.16 KND88998.1 - 3.8e-46 157.4 0.1 1.1e-42 146.1 0.0 2.0 1 1 1 2 2 2 2 Ham1 family Peptidase_M16_C PF05193.21 KND89000.1 - 6.9e-54 182.6 0.0 4.4e-53 180.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND89000.1 - 4.9e-41 140.2 0.0 2.2e-38 131.6 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) DUF5427 PF10310.9 KND89001.1 - 7.5 5.4 22.1 6.1 5.7 10.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5427) S1 PF00575.23 KND89002.1 - 3.1e-73 242.1 38.7 1.5e-13 50.9 0.5 13.0 13 0 0 13 13 13 12 S1 RNA binding domain RNase_II_C_S1 PF18614.1 KND89002.1 - 1.4e-05 25.0 3.9 6.2 6.9 0.0 6.3 6 0 0 6 6 6 2 RNase II-type exonuclease C-terminal S1 domain Suf PF05843.14 KND89002.1 - 0.00012 22.2 6.9 0.0019 18.2 0.1 3.2 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KND89002.1 - 0.00018 22.0 0.6 0.94 10.5 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat S1_2 PF13509.6 KND89002.1 - 0.0019 18.2 0.1 48 4.1 0.0 5.1 5 0 0 5 5 5 0 S1 domain NRDE-2 PF08424.10 KND89002.1 - 0.0052 16.0 0.9 0.17 11.0 0.1 2.6 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KND89002.1 - 0.012 16.1 0.1 9.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KND89003.1 - 2.7e-15 56.1 0.0 5.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89003.1 - 1.2e-14 54.1 27.5 1.6e-07 31.3 11.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 KND89004.1 - 3.1e-19 69.5 0.1 4.6e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Amidase PF01425.21 KND89005.1 - 5.4e-30 104.7 0.2 1e-29 103.8 0.2 1.4 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.28 KND89006.1 - 8.5e-72 242.0 0.0 1e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND89006.1 - 1e-10 42.4 1.9 2.5e-10 41.2 0.9 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Med18 PF09637.10 KND89012.1 - 1.9e-25 90.2 0.0 2.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Med18 protein DUF2931 PF11153.8 KND89013.1 - 0.19 11.4 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) adh_short PF00106.25 KND89014.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND89014.1 - 0.00059 19.5 0.0 0.00071 19.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND89015.1 - 1.3e-33 116.1 0.0 5.8e-32 110.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND89015.1 - 5.1e-25 88.4 0.0 5.6e-23 81.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND89015.1 - 0.045 13.7 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KND89016.1 - 8.8e-10 38.2 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KND89016.1 - 1.5e-09 37.7 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND89016.1 - 0.017 14.2 0.0 0.038 13.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Asp_Glu_race PF01177.22 KND89016.1 - 0.071 12.9 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Gly_transf_sug PF04488.15 KND89017.1 - 3.3e-08 34.1 0.0 7.3e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KND89017.1 - 0.0019 17.6 0.3 0.0041 16.5 0.1 1.3 1 1 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain LDB19 PF13002.7 KND89018.1 - 4.3e-37 127.7 0.6 1.4e-36 126.1 0.2 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 KND89018.1 - 3.8e-05 23.8 0.0 7.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 KND89018.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein DIOX_N PF14226.6 KND89019.1 - 5.5e-19 69.1 0.0 1.2e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND89019.1 - 4.8e-12 46.3 0.0 7.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KND89020.1 - 3.9e-29 101.8 0.0 7.1e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND89020.1 - 7.8e-14 52.0 0.1 4.3e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4783 PF16022.5 KND89020.1 - 0.21 11.7 0.0 0.38 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) DLH PF01738.18 KND89021.1 - 5.6e-07 29.3 0.0 6.8e-06 25.8 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KND89021.1 - 6.8e-06 25.5 0.0 0.0047 16.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KND89021.1 - 0.00047 19.8 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 KND89021.1 - 0.00097 18.7 0.1 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND89021.1 - 0.001 18.8 0.0 0.0027 17.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 KND89021.1 - 0.0017 17.1 0.0 0.005 15.5 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) APH PF01636.23 KND89022.1 - 1.8e-10 41.2 0.0 2.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND89022.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF4470 PF14737.6 KND89023.1 - 9.4e-13 48.2 0.1 1.8e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KND89023.1 - 2e-07 31.0 6.3 4.2e-07 30.0 6.3 1.5 1 0 0 1 1 1 1 MYND finger PmoA PF14100.6 KND89023.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA zf-C6H2 PF15801.5 KND89023.1 - 0.092 13.1 6.1 0.19 12.0 6.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese PF00581.20 KND89024.1 - 0.00013 22.4 0.0 0.0002 21.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.15 KND89025.1 - 7.8e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KND89025.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold DNA_ligase_A_M PF01068.21 KND89026.1 - 1.3e-43 149.0 0.0 2.6e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KND89026.1 - 1.5e-42 145.9 0.0 2.7e-42 145.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KND89026.1 - 1.9e-18 67.3 0.0 3.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 KND89026.1 - 5.3e-16 58.8 0.0 2.3e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KND89026.1 - 2.6e-14 53.6 0.2 9.2e-14 51.9 0.0 2.2 2 0 0 2 2 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 KND89026.1 - 1.5e-08 34.9 0.0 5.9e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KND89026.1 - 4.5e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.7 KND89026.1 - 0.0093 15.9 0.2 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain mRNA_cap_enzyme PF01331.19 KND89026.1 - 0.018 14.9 0.0 0.77 9.6 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain LIG3_BRCT PF16759.5 KND89026.1 - 0.021 15.1 0.0 2 8.8 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KND89026.1 - 0.041 13.8 0.0 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Bac_globin PF01152.21 KND89026.1 - 0.18 12.0 0.3 0.49 10.6 0.0 1.9 2 0 0 2 2 1 0 Bacterial-like globin acVLRF1 PF18859.1 KND89026.1 - 4.3 7.6 8.5 1.7 9.0 0.1 3.0 3 0 0 3 3 3 0 Actinobacteria/chloroflexi VLRF1 release factor Adenylsucc_synt PF00709.21 KND89027.1 - 1e-167 558.3 0.0 1.2e-167 558.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CRCB PF02537.15 KND89028.1 - 3.8e-35 120.1 20.4 5e-22 78.0 9.8 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 KND89029.1 - 1.3e-71 240.4 0.0 1.5e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KND89029.1 - 1e-06 28.3 0.0 1.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KND89029.1 - 0.049 13.7 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain ThiJ_like PF17124.5 KND89031.1 - 3.9e-52 176.8 0.0 8.3e-52 175.7 0.0 1.4 2 0 0 2 2 2 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 KND89031.1 - 1.8e-09 37.6 0.0 1.1e-08 35.0 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.19 KND89031.1 - 0.065 13.1 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Fungal_trans_2 PF11951.8 KND89032.1 - 1e-22 80.5 0.0 2.3e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89032.1 - 4.1e-08 33.2 5.3 9.1e-08 32.1 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 KND89033.1 - 9.3e-05 21.2 0.1 0.0001 21.1 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TcdB_toxin_midN PF12256.8 KND89033.1 - 0.21 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region OPT PF03169.15 KND89034.1 - 9.4e-10 37.8 0.0 1.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DctQ PF04290.12 KND89034.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Glyco_transf_20 PF00982.21 KND89036.1 - 1.6e-150 502.0 0.0 2.2e-150 501.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KND89036.1 - 1.2e-69 234.0 0.0 2.3e-69 233.1 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Sugar_tr PF00083.24 KND89037.1 - 5.2e-127 424.4 28.0 6e-127 424.2 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND89037.1 - 1.8e-20 73.2 44.4 7.7e-14 51.4 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 KND89039.1 - 1.5e-146 488.5 0.0 2e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KND89039.1 - 5.7e-21 74.8 0.1 9.8e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KND89039.1 - 1.6e-07 31.5 0.1 2.8e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CFEM PF05730.11 KND89041.1 - 6.5e-13 48.6 12.4 1e-12 48.0 12.4 1.3 1 0 0 1 1 1 1 CFEM domain Pyr_redox_2 PF07992.14 KND89042.1 - 1.6e-53 181.9 0.3 2e-53 181.6 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KND89042.1 - 4.7e-20 71.9 0.0 1.9e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KND89042.1 - 1.1e-18 67.5 0.6 8.2e-16 58.3 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND89042.1 - 0.0061 15.7 0.1 0.064 12.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 KND89042.1 - 0.0072 15.5 4.2 0.016 14.3 1.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KND89042.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KND89042.1 - 0.039 13.8 1.0 3.3 7.5 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KND89042.1 - 0.076 12.6 0.6 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KND89042.1 - 0.087 13.1 5.5 3.9 7.8 0.4 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND89042.1 - 0.15 11.3 0.0 0.65 9.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Promethin PF16015.5 KND89043.1 - 0.082 12.8 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 Promethin DUF4750 PF15938.5 KND89043.1 - 0.17 11.5 1.6 0.28 10.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) PgaD PF13994.6 KND89043.1 - 0.18 11.8 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Acyl_transf_1 PF00698.21 KND89044.1 - 1.1e-14 54.6 0.4 1.9e-14 53.9 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KND89044.1 - 1.8e-14 53.7 0.0 3.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF2974 PF11187.8 KND89044.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FBPase_glpX PF03320.13 KND89045.1 - 0.14 11.0 0.1 0.69 8.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded LapA_dom PF06305.11 KND89045.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NifZ PF04319.13 KND89047.1 - 0.12 12.2 0.3 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 NifZ domain PLAC8 PF04749.17 KND89049.1 - 4.8e-24 85.2 10.0 7.9e-24 84.5 10.0 1.3 1 0 0 1 1 1 1 PLAC8 family ACT_3 PF10000.9 KND89050.1 - 1.9e-15 56.5 0.1 4.2e-15 55.4 0.0 1.7 2 0 0 2 2 1 1 ACT domain HTH_29 PF13551.6 KND89050.1 - 5.6e-10 39.1 0.4 1.1e-09 38.1 0.4 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 KND89050.1 - 6.8e-07 29.3 1.1 1.7e-06 28.1 1.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 KND89050.1 - 6.5e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 KND89050.1 - 0.0016 17.9 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding ACT_7 PF13840.6 KND89050.1 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain MarR_2 PF12802.7 KND89050.1 - 0.0035 17.2 0.4 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 MarR family HTH_32 PF13565.6 KND89050.1 - 0.0037 17.9 3.7 0.026 15.1 0.5 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_50 PF18024.1 KND89050.1 - 0.015 14.9 0.7 0.065 12.9 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Fe_dep_repress PF01325.19 KND89050.1 - 0.023 14.9 0.0 0.089 13.0 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain HTH_Crp_2 PF13545.6 KND89050.1 - 0.026 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MarR PF01047.22 KND89050.1 - 0.2 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_1 PF00126.27 KND89050.1 - 0.28 11.2 1.7 4.8 7.2 0.1 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family PET PF06297.14 KND89050.1 - 0.45 10.8 1.9 0.86 9.9 1.9 1.4 1 0 0 1 1 1 0 PET Domain SCAB_CC PF16712.5 KND89051.1 - 0.045 13.6 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein JAB PF01398.21 KND89052.1 - 6.3e-32 110.0 0.1 2.1e-31 108.3 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KND89052.1 - 3.4e-23 82.4 0.2 6.5e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KND89052.1 - 5.5e-06 26.2 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KND89052.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) MDM10 PF12519.8 KND89053.1 - 2.1e-166 554.4 0.0 6.4e-140 467.1 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KND89053.1 - 0.065 12.7 0.4 8.1 5.8 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic porin Zip PF02535.22 KND89054.1 - 1.5e-65 221.6 0.5 1.8e-65 221.4 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PsbL PF02419.17 KND89054.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.6 3 0 0 3 3 3 0 PsbL protein Antimicrobial10 PF08105.11 KND89055.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Metchnikowin family ACPS PF01648.20 KND89059.1 - 0.042 14.0 0.3 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily RAG1 PF12940.7 KND89059.1 - 0.14 10.2 0.0 0.2 9.7 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase Vps16_N PF04841.13 KND89060.1 - 4.3e-86 289.2 0.0 8.3e-86 288.3 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 KND89060.1 - 2.4e-74 250.3 0.0 3.5e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 KND89060.1 - 0.092 13.1 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ATG16 PF08614.11 KND89061.1 - 1.1e-53 182.5 18.8 1.3e-53 182.3 18.8 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) SCP-1 PF05483.12 KND89061.1 - 0.00022 19.4 2.2 0.0003 19.0 2.2 1.2 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) APG6_N PF17675.1 KND89061.1 - 0.013 16.0 12.1 0.013 16.0 12.1 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 KND89061.1 - 0.016 15.4 13.1 0.031 14.5 0.8 3.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain Tnp_22_trimer PF17489.2 KND89061.1 - 0.086 12.8 9.6 1.2 9.1 0.1 4.0 4 0 0 4 4 4 0 L1 transposable element trimerization domain SlyX PF04102.12 KND89061.1 - 0.28 11.8 11.0 7.7 7.2 3.1 3.3 2 1 1 3 3 3 0 SlyX Spc7 PF08317.11 KND89061.1 - 0.28 10.0 12.5 7.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CdvA PF18822.1 KND89061.1 - 0.43 10.4 8.8 2.9 7.7 6.2 2.8 2 1 0 2 2 2 0 CdvA-like coiled-coil domain DUF4349 PF14257.6 KND89061.1 - 0.91 8.9 13.8 5.8 6.3 9.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) Sec2p PF06428.11 KND89061.1 - 2.8 8.0 14.4 1.4 9.0 4.3 3.2 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF4140 PF13600.6 KND89061.1 - 5.3 7.5 15.4 2.7 8.5 0.1 3.5 2 1 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Oxidored_q6 PF01058.22 KND89062.1 - 7.3e-23 80.8 0.1 1e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DEC-1_C PF04626.13 KND89062.1 - 0.16 12.3 0.3 0.26 11.7 0.3 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region FA_desaturase PF00487.24 KND89066.1 - 2.4e-31 109.5 20.3 3.5e-31 109.0 20.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Fungal_trans PF04082.18 KND89067.1 - 3e-09 36.3 0.2 8.2e-09 34.9 0.1 1.8 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89067.1 - 2.2e-05 24.5 7.0 2.2e-05 24.5 7.0 3.1 3 1 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KND89067.1 - 0.0022 18.4 1.5 0.0022 18.4 1.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type BTB_3 PF16017.5 KND89067.1 - 0.021 14.9 0.2 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 BTB/POZ domain zf-C2H2_4 PF13894.6 KND89067.1 - 0.032 15.0 18.0 0.17 12.8 0.8 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger PyrI_C PF02748.15 KND89067.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 KND89067.1 - 0.39 11.1 7.3 7.4 7.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KND89067.1 - 0.86 9.7 11.6 0.35 10.9 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND89067.1 - 4.2 8.0 10.9 0.64 10.6 2.5 3.7 3 0 0 3 3 3 0 Zinc-finger double domain PNK3P PF08645.11 KND89068.1 - 2e-53 180.4 0.0 3e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KND89068.1 - 7.3e-28 97.5 0.0 3.4e-25 88.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 KND89068.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 KND89068.1 - 0.04 13.8 0.0 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KND89068.1 - 0.089 12.1 0.1 0.57 9.4 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.6 KND89068.1 - 0.093 13.3 0.1 1.3 9.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 KND89068.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sugar_tr PF00083.24 KND89069.1 - 7.9e-78 262.3 19.4 9.8e-78 262.0 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND89069.1 - 4.2e-13 49.0 63.7 1.9e-11 43.5 35.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 KND89070.1 - 3.8e-59 200.7 0.0 5.6e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2568 PF10823.8 KND89070.1 - 0.24 11.7 4.0 0.56 10.5 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2568) Methyltransf_23 PF13489.6 KND89071.1 - 1.2e-20 74.0 0.0 1.9e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89071.1 - 1e-11 45.4 0.0 4e-11 43.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89071.1 - 1e-08 35.8 0.0 4.1e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND89071.1 - 1.4e-08 35.3 0.0 3.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89071.1 - 2.1e-05 24.4 0.0 0.00033 20.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KND89071.1 - 0.00014 21.3 0.0 0.0018 17.6 0.0 2.4 2 1 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 KND89071.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 KND89071.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KND89071.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KND89071.1 - 0.049 12.9 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KND89071.1 - 0.049 13.4 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PKD PF00801.20 KND89071.1 - 0.065 13.1 0.6 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 PKD domain Ubie_methyltran PF01209.18 KND89071.1 - 0.079 12.3 0.0 2.8 7.2 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Fungal_trans PF04082.18 KND89072.1 - 1.1e-12 47.5 0.0 1.7e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEP PF00610.21 KND89072.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.16 KND89073.1 - 8.6e-20 71.0 21.6 8.6e-12 44.6 13.7 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Zn_clus PF00172.18 KND89074.1 - 1.8e-08 34.3 10.1 2.9e-08 33.7 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND89074.1 - 0.0012 17.9 0.2 0.0021 17.1 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRP14 PF15459.6 KND89074.1 - 0.005 17.4 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 60S ribosome biogenesis protein Rrp14 zf-C2H2 PF00096.26 KND89075.1 - 1.3e-05 25.3 11.7 0.0047 17.3 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND89075.1 - 0.00028 21.2 3.8 0.00028 21.2 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND89075.1 - 0.0006 20.4 11.3 0.074 13.9 2.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KND89075.1 - 1.1 9.1 6.0 2.1 8.2 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF2434 PF10361.9 KND89076.1 - 1.5e-133 444.3 12.1 2e-133 443.9 12.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 KND89077.1 - 3.9e-37 127.4 0.5 3.9e-37 127.4 0.5 2.7 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Gelsolin PF00626.22 KND89077.1 - 4.6e-29 100.1 0.0 6.8e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat RRM_1 PF00076.22 KND89079.1 - 4.8e-13 48.7 0.0 8.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABA_GPCR PF12430.8 KND89080.1 - 3.9e-53 179.9 0.1 3.9e-53 179.9 0.1 1.6 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KND89080.1 - 3e-24 84.9 0.3 2.7e-23 81.8 0.0 2.3 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF2388 PF09498.10 KND89080.1 - 0.071 13.1 1.8 0.17 11.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Usp PF00582.26 KND89081.1 - 6.4e-13 49.4 0.0 6.4e-13 49.4 0.0 3.8 3 2 1 4 4 4 1 Universal stress protein family Paf67 PF10255.9 KND89082.1 - 1.2e-155 518.5 0.4 1.4e-155 518.3 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KND89082.1 - 0.048 13.8 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 KND89084.1 - 5.5e-59 199.0 0.0 1.2e-58 197.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KND89084.1 - 5.5e-16 58.4 0.0 1.2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND89084.1 - 2.2e-08 34.4 0.0 7.1e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KND89084.1 - 3.1e-07 30.4 0.0 6.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 KND89084.1 - 0.0072 16.1 0.0 0.061 13.1 0.0 2.5 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KND89084.1 - 0.012 15.6 0.0 0.045 13.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase PP_M1 PF03012.14 KND89084.1 - 0.072 12.6 0.8 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoprotein Amidohydro_3 PF07969.11 KND89085.1 - 1.3e-70 239.2 0.3 1.6e-70 238.9 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KND89085.1 - 2.6e-09 36.8 0.1 0.00039 19.8 0.0 3.4 3 1 0 3 3 3 2 Amidohydrolase family FMN_bind_2 PF04299.12 KND89086.1 - 1e-50 171.8 0.0 1.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.8 KND89087.1 - 2.4e-42 145.2 0.0 2.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89087.1 - 2.7e-07 30.6 7.3 2.7e-07 30.6 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KND89088.1 - 0.84 9.6 15.0 0.92 9.4 4.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ADH_zinc_N PF00107.26 KND89089.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND89089.1 - 0.04 15.0 0.0 0.14 13.3 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Acyl-CoA_dh_2 PF08028.11 KND89090.1 - 2.6e-14 53.6 0.4 3.8e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KND89090.1 - 1.8e-05 24.8 0.2 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KND89090.1 - 0.0015 18.8 0.2 0.0029 17.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND89090.1 - 0.0042 17.7 0.0 0.0084 16.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain OPT PF03169.15 KND89091.1 - 1.5e-143 479.7 46.6 1.7e-143 479.5 46.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CTF_NFI PF00859.18 KND89092.1 - 0.0054 16.7 2.9 0.0086 16.0 2.9 1.3 1 0 0 1 1 1 1 CTF/NF-I family transcription modulation region SSP160 PF06933.11 KND89092.1 - 1.2 7.3 6.5 1.6 6.8 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Amidohydro_3 PF07969.11 KND89093.1 - 4.6e-13 49.4 0.1 1.1e-08 35.1 0.1 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KND89093.1 - 4.6e-12 45.9 0.0 6.1e-11 42.2 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family LigB PF02900.18 KND89094.1 - 2.6e-25 89.0 0.0 3.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GST_C_3 PF14497.6 KND89095.1 - 4.7e-29 100.5 0.0 1e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KND89095.1 - 0.00038 20.4 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND89095.1 - 0.00046 20.4 0.0 0.001 19.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KND89095.1 - 0.15 12.4 0.0 2.1 8.8 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NAD_binding_2 PF03446.15 KND89096.1 - 8e-24 84.6 0.1 1.5e-23 83.7 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND89096.1 - 2.8e-06 27.8 0.1 8.4e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KND89096.1 - 4e-06 26.9 0.0 6.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KND89096.1 - 5.6e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KND89096.1 - 6.2e-05 22.6 0.1 0.00089 18.9 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KND89096.1 - 0.0011 19.2 0.2 0.0042 17.3 0.2 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_11 PF14833.6 KND89096.1 - 0.0019 18.4 0.0 0.0045 17.2 0.0 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh_N PF03721.14 KND89096.1 - 0.018 14.6 0.8 5.3 6.6 0.1 2.5 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SBF PF01758.16 KND89097.1 - 4.2e-52 176.7 9.9 4.2e-52 176.7 9.9 1.9 2 1 0 2 2 2 1 Sodium Bile acid symporter family Methyltransf_31 PF13847.6 KND89098.1 - 3.2e-24 85.5 0.0 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89098.1 - 4.2e-18 65.8 0.1 8.3e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND89098.1 - 7.2e-16 58.2 0.1 1.1e-15 57.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KND89098.1 - 4.9e-15 56.0 0.1 1.2e-14 54.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89098.1 - 2.9e-09 37.5 0.0 4.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND89098.1 - 3.4e-08 33.5 0.0 5.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND89098.1 - 2.9e-05 23.9 0.0 5.2e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KND89098.1 - 3.6e-05 23.3 0.1 5.2e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 KND89098.1 - 0.00018 21.5 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND89098.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.17 KND89098.1 - 0.0037 16.4 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 Fibrillarin CMAS PF02353.20 KND89098.1 - 0.005 16.2 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KND89098.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 KND89098.1 - 0.067 13.3 0.1 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.13 KND89098.1 - 0.1 12.1 0.2 0.22 11.1 0.2 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_19 PF04672.12 KND89098.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 S-adenosyl methyltransferase Abhydrolase_4 PF08386.10 KND89100.1 - 6.8e-19 67.9 0.1 2.2e-18 66.3 0.1 1.9 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KND89100.1 - 1.2e-16 61.1 0.2 3e-06 27.1 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Ricin_B_lectin PF00652.22 KND89101.1 - 8.9e-08 32.4 0.0 0.002 18.4 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain GFA PF04828.14 KND89103.1 - 3.8e-14 52.8 0.4 3.8e-14 52.8 0.4 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme EI24 PF07264.11 KND89104.1 - 7.3e-08 32.9 21.5 1.5e-07 31.9 21.5 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) CENP-X PF09415.10 KND89105.1 - 0.21 11.9 0.7 1.1 9.6 0.0 2.3 2 1 0 2 2 2 0 CENP-S associating Centromere protein X ketoacyl-synt PF00109.26 KND89106.1 - 5.7e-84 281.6 0.0 1.2e-83 280.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KND89106.1 - 7.6e-40 137.4 0.0 2e-39 136.0 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND89106.1 - 2.5e-34 117.8 0.2 6.5e-34 116.5 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KND89106.1 - 8.7e-23 81.3 3.7 4.2e-18 65.9 0.0 4.4 4 1 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KND89106.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KND89106.1 - 4.1e-18 66.4 0.0 1e-17 65.1 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KND89106.1 - 7.3e-15 55.1 0.8 5.7e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KND89106.1 - 8.6e-08 32.6 0.0 2.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KND89106.1 - 7.4e-06 25.5 0.1 0.00019 20.9 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 KND89106.1 - 0.0002 22.1 0.0 0.0023 18.6 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family ACP_syn_III PF08545.10 KND89106.1 - 0.38 10.6 2.2 2 8.3 0.7 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AMP-binding PF00501.28 KND89107.1 - 2.3e-34 118.7 0.0 1e-33 116.6 0.0 2.1 2 1 1 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KND89107.1 - 6.7e-19 68.1 0.0 1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KND89107.1 - 4.4e-06 26.3 0.0 3.2e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KND89107.1 - 8.5e-05 22.8 1.7 0.00046 20.5 0.0 2.9 3 1 0 3 3 3 1 Phosphopantetheine attachment site DUF1995 PF09353.10 KND89107.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) KR PF08659.10 KND89107.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 KR domain Abhydrolase_3 PF07859.13 KND89108.1 - 1.2e-17 64.5 0.0 2.5e-17 63.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KND89108.1 - 0.00094 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND89108.1 - 0.069 12.4 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 KND89109.1 - 3.3e-29 102.2 0.0 1.3e-28 100.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KND89109.1 - 1.1e-08 34.9 0.0 4.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND89109.1 - 3.4e-07 30.4 0.1 4.9e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND89109.1 - 3.8e-07 29.7 0.1 0.00033 20.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND89109.1 - 7.6e-06 25.4 0.4 0.0046 16.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND89109.1 - 4.7e-05 22.6 1.7 4.8e-05 22.6 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KND89109.1 - 5e-05 23.0 1.3 0.00025 20.7 0.6 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND89109.1 - 0.00011 22.7 0.4 0.12 13.0 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND89109.1 - 0.0011 19.0 0.2 0.39 10.7 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KND89109.1 - 0.0048 16.2 0.1 0.01 15.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 KND89109.1 - 0.0051 17.1 0.3 0.023 15.0 0.0 2.2 3 0 0 3 3 2 1 TrkA-N domain Trp_halogenase PF04820.14 KND89109.1 - 0.0072 15.2 0.1 0.015 14.2 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 KND89109.1 - 0.032 13.3 0.5 0.71 8.9 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 KND89109.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KND89109.1 - 0.17 11.9 0.4 0.35 10.9 0.4 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Myb_DNA-binding PF00249.31 KND89110.1 - 3.1e-34 116.9 5.7 2.6e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND89110.1 - 2.2e-25 88.6 7.4 2.2e-14 53.4 0.1 3.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KND89110.1 - 5.7e-06 26.4 0.1 0.042 14.1 0.2 2.3 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 KND89110.1 - 1.5e-05 24.8 0.0 0.01 15.7 0.1 2.6 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 KND89110.1 - 0.021 14.9 0.0 0.79 9.8 0.1 2.4 1 1 1 2 2 2 0 SLIDE MFS_1 PF07690.16 KND89111.1 - 3.3e-29 101.9 57.9 1e-28 100.3 52.6 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 KND89112.1 - 3.1e-54 184.5 0.0 6.6e-54 183.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KND89112.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KND89112.1 - 2e-05 24.0 0.0 0.00095 18.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND89112.1 - 0.0014 19.2 0.1 0.013 16.1 0.0 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND89112.1 - 0.0017 17.5 0.2 0.077 12.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KND89112.1 - 0.0039 16.5 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KND89112.1 - 0.0094 15.0 0.3 0.017 14.2 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KND89112.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND89112.1 - 0.047 13.3 0.6 0.62 9.6 0.6 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KND89112.1 - 0.051 12.3 0.1 0.078 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 KND89112.1 - 0.063 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND89112.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KND89112.1 - 0.29 10.2 0.2 0.43 9.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_2 PF00891.18 KND89113.1 - 3.8e-21 75.4 0.0 3e-18 65.9 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_31 PF13847.6 KND89113.1 - 0.00046 20.0 0.0 0.00082 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AA_permease_2 PF13520.6 KND89114.1 - 1.4e-80 271.2 38.2 1.4e-80 271.2 38.2 1.4 1 1 1 2 2 2 1 Amino acid permease E1-E2_ATPase PF00122.20 KND89115.1 - 6.9e-33 113.7 0.4 1.3e-31 109.6 0.4 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KND89115.1 - 8.4e-15 55.6 2.6 4.5e-14 53.2 2.6 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND89115.1 - 5.2e-12 45.3 0.0 1.3e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KND89115.1 - 4.3e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 KND89115.1 - 6.5e-05 22.7 4.0 6.8e-05 22.6 0.2 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Gln-synt_C PF00120.24 KND89116.1 - 4.7e-75 252.7 0.0 5.6e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Fumerase PF05681.14 KND89116.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) Methyltransf_23 PF13489.6 KND89117.1 - 8.8e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C65 PF10275.9 KND89118.1 - 2.3e-64 217.2 0.0 3e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain MFS_1 PF07690.16 KND89119.1 - 1.2e-21 77.1 53.6 2.7e-20 72.6 35.6 1.8 2 1 1 3 3 3 2 Major Facilitator Superfamily PCI PF01399.27 KND89119.1 - 1.1e-14 54.8 0.0 2.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF5345 PF17280.2 KND89119.1 - 0.42 10.6 2.2 1.9 8.5 2.2 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) NUDIX PF00293.28 KND89121.1 - 2.8e-08 33.9 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PP-binding PF00550.25 KND89121.1 - 0.097 13.0 0.0 4.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphopantetheine attachment site ICAT PF06384.11 KND89122.1 - 0.064 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT RRM_1 PF00076.22 KND89123.1 - 5.1e-07 29.4 0.0 2.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRR1 PF07985.12 KND89126.1 - 0.08 13.0 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 SRR1 NMO PF03060.15 KND89127.1 - 4.9e-31 108.3 8.7 6.9e-25 88.1 3.9 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KND89127.1 - 2.8e-09 36.4 0.6 3.5e-05 23.0 0.6 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND89127.1 - 3.5e-05 23.0 4.9 5.6e-05 22.3 4.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KND89127.1 - 0.00048 19.4 0.2 0.00082 18.6 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NmrA PF05368.13 KND89128.1 - 5.9e-38 130.7 0.0 7.2e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND89128.1 - 9.1e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND89128.1 - 3.9e-05 22.8 0.0 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KND89128.1 - 0.00012 21.7 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KND89128.1 - 0.00074 19.8 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KND89128.1 - 0.00098 19.1 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 KND89128.1 - 0.053 13.0 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase PALP PF00291.25 KND89128.1 - 0.073 12.5 0.1 0.14 11.5 0.1 1.4 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme adh_short_C2 PF13561.6 KND89128.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2235 PF09994.9 KND89129.1 - 1.7e-74 250.8 0.0 2.1e-74 250.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DoxX_2 PF13564.6 KND89129.1 - 0.096 12.8 0.5 0.3 11.2 0.1 1.8 1 1 1 2 2 2 0 DoxX-like family An_peroxidase PF03098.15 KND89130.1 - 0.016 13.8 0.0 0.023 13.3 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase DPBB_1 PF03330.18 KND89132.1 - 1.9e-09 37.7 0.1 3.5e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KND89132.1 - 0.028 14.3 0.3 0.04 13.8 0.3 1.3 1 0 0 1 1 1 0 Barwin family Inhibitor_I68 PF10468.9 KND89132.1 - 0.04 14.3 0.2 0.056 13.8 0.2 1.2 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 DUF5330 PF17264.2 KND89132.1 - 0.15 12.1 0.1 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5330) DUF3883 PF13020.6 KND89133.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3883) Ribosomal_S14 PF00253.21 KND89134.1 - 5.7e-22 77.2 3.2 1.2e-21 76.2 0.9 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Peptidase_C14 PF00656.22 KND89139.1 - 3.6e-58 197.5 0.0 4.4e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain SpvD PF05563.12 KND89139.1 - 0.2 11.2 0.0 0.4 10.3 0.0 1.6 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD APH PF01636.23 KND89140.1 - 8.4e-17 61.9 1.2 2.7e-16 60.2 0.8 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND89140.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase WW PF00397.26 KND89141.1 - 1.8e-09 37.5 3.7 1.8e-09 37.5 3.7 1.9 2 0 0 2 2 2 1 WW domain Ank_4 PF13637.6 KND89143.1 - 1.8e-39 133.6 2.4 8.5e-09 35.8 0.1 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND89143.1 - 2.4e-37 127.4 5.8 2.1e-13 50.7 1.2 5.7 3 1 0 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 KND89143.1 - 5.1e-34 115.2 11.1 0.00017 21.9 0.2 8.5 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KND89143.1 - 1e-29 99.2 0.7 0.0015 18.8 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KND89143.1 - 1.4e-22 79.5 7.1 7.8e-05 22.9 0.1 6.9 1 1 7 8 8 8 7 Ankyrin repeats (many copies) HEAT_2 PF13646.6 KND89143.1 - 1.5e-05 25.3 13.3 0.00015 22.1 2.4 3.9 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KND89143.1 - 0.00066 19.7 0.3 0.15 12.4 0.1 3.2 3 0 0 3 3 3 1 HEAT repeat FLgD_tudor PF13861.6 KND89143.1 - 0.07 13.4 2.0 0.99 9.7 0.3 3.2 2 1 0 2 2 2 0 FlgD Tudor-like domain Cohesin_HEAT PF12765.7 KND89143.1 - 0.089 13.1 0.8 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KND89143.1 - 0.46 11.0 4.6 1.6 9.3 2.3 3.1 2 1 1 3 3 3 0 HEAT-like repeat DUF2018 PF09442.10 KND89145.1 - 0.22 12.5 0.1 0.44 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) WD40 PF00400.32 KND89146.1 - 6.9e-08 33.0 1.7 0.15 13.0 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 KND89146.1 - 0.022 15.3 0.2 19 5.9 0.0 3.9 3 1 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.6 KND89146.1 - 0.035 13.7 0.0 0.25 10.9 0.0 2.2 3 0 0 3 3 3 0 PQQ-like domain ANAPC4_WD40 PF12894.7 KND89146.1 - 0.079 13.3 0.0 4.4 7.7 0.0 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Complex1_LYR PF05347.15 KND89149.1 - 8.1e-20 70.6 2.6 1.9e-19 69.4 2.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND89149.1 - 6.2e-06 26.9 0.1 1.1e-05 26.1 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like VitD-bind_III PF09164.10 KND89149.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.7 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Bys1 PF04681.12 KND89150.1 - 2.5e-18 66.5 0.4 2.8e-18 66.3 0.4 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Tup_N PF08581.10 KND89152.1 - 0.031 14.6 0.8 0.052 13.8 0.8 1.3 1 0 0 1 1 1 0 Tup N-terminal UCH_C PF18031.1 KND89152.1 - 0.14 12.1 3.6 0.26 11.2 3.6 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases FMO-like PF00743.19 KND89154.1 - 3e-14 52.4 0.2 3.5e-13 48.8 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KND89154.1 - 3.2e-09 36.9 0.0 1.6e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND89154.1 - 2.4e-08 33.6 0.0 4.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND89154.1 - 0.00025 20.3 0.0 0.0014 17.8 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KND89154.1 - 0.00027 20.6 0.8 0.25 10.9 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND89154.1 - 0.00071 18.9 0.1 0.035 13.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND89154.1 - 0.056 13.4 0.9 8.8 6.3 0.1 3.1 3 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KND89154.1 - 0.095 11.4 0.3 0.89 8.2 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KND89154.1 - 0.49 9.6 1.2 0.64 9.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Bac_luciferase PF00296.20 KND89155.1 - 1.9e-45 155.6 0.7 2.8e-45 155.1 0.7 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KND89156.1 - 2.8e-12 46.2 31.5 2.8e-12 46.2 31.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KND89156.1 - 8.8e-05 22.3 4.0 8.8e-05 22.3 4.0 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 adh_short_C2 PF13561.6 KND89157.1 - 3.1e-44 151.3 0.0 4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND89157.1 - 5.2e-41 140.2 0.0 7.2e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND89157.1 - 1.5e-12 47.8 0.6 7.7e-12 45.5 0.6 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND89157.1 - 0.00024 20.6 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND89157.1 - 0.006 15.6 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 KND89159.1 - 1.9e-12 46.8 0.2 1.6e-11 43.8 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89159.1 - 0.00021 21.4 2.4 0.00044 20.3 2.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KND89160.1 - 1.9e-57 195.3 0.0 2.4e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KND89160.1 - 0.0026 17.2 0.4 0.014 14.9 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KND89160.1 - 0.0046 16.8 0.2 0.032 14.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_3 PF01596.17 KND89161.1 - 1.7e-21 76.4 0.0 2e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 KND89161.1 - 2.1e-16 60.8 0.0 3.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89161.1 - 2.1e-10 40.6 0.0 2.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89161.1 - 1.7e-06 28.6 0.0 3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KND89161.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 KND89161.1 - 1.7e-05 24.7 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KND89161.1 - 8.3e-05 23.2 0.0 0.00017 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND89161.1 - 0.0014 18.4 0.0 0.0029 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89161.1 - 0.0021 18.8 0.0 0.0044 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.17 KND89161.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_18 PF12847.7 KND89161.1 - 0.026 14.5 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PTase_Orf2 PF11468.8 KND89161.1 - 0.052 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 UPF0020 PF01170.18 KND89161.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 KND89161.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1 PF07690.16 KND89162.1 - 3.7e-25 88.6 67.8 5.2e-23 81.5 63.7 3.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89162.1 - 1.4e-09 37.4 9.9 1.4e-09 37.4 9.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KND89162.1 - 0.11 10.8 14.4 0.34 9.1 3.5 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CclA_1 PF16942.5 KND89162.1 - 6 7.2 12.3 0.71 10.2 0.4 3.4 3 0 0 3 3 3 0 Putative cyclic bacteriocin p450 PF00067.22 KND89163.1 - 3.2e-51 174.5 0.0 1.7e-40 139.2 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 Amidohydro_2 PF04909.14 KND89168.1 - 1.8e-23 83.8 0.1 2.7e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KND89168.1 - 0.051 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family AA_permease_2 PF13520.6 KND89169.1 - 4.1e-82 276.3 24.7 5.2e-82 275.9 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND89169.1 - 4.5e-11 42.0 26.4 7e-11 41.4 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 KND89169.1 - 0.00011 21.0 8.0 0.00011 21.0 8.0 1.6 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 KND89171.1 - 9.1e-51 172.8 87.3 8.1e-43 146.7 56.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.7 KND89171.1 - 0.33 11.7 0.1 0.33 11.7 0.1 5.0 5 2 0 5 5 5 0 PrgI family protein DUF872 PF05915.12 KND89171.1 - 0.81 9.9 3.7 1.3 9.2 2.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.7 KND89171.1 - 1.6 7.5 28.9 0.072 11.9 9.5 2.4 2 0 0 2 2 2 0 MFS_1 like family TPT PF03151.16 KND89172.1 - 1.5e-19 70.4 23.1 3.8e-19 69.1 23.1 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KND89172.1 - 0.013 15.6 9.6 0.013 15.6 9.6 3.5 4 0 0 4 4 4 0 EamA-like transporter family COBRA PF04833.15 KND89173.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 COBRA-like protein zf-C2HC_2 PF13913.6 KND89175.1 - 0.017 15.0 2.8 0.28 11.1 0.0 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 KND89175.1 - 0.059 13.7 7.6 0.25 11.7 0.6 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KND89175.1 - 0.13 13.1 10.2 0.79 10.7 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KND89175.1 - 0.85 10.2 12.1 3.2 8.4 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Abhydrolase_1 PF00561.20 KND89176.1 - 5.3e-47 160.6 0.0 1.2e-46 159.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KND89176.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Glyco_hydro_12 PF01670.16 KND89178.1 - 3.7e-25 89.2 6.0 1.4e-24 87.3 6.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 T2SSL PF05134.13 KND89178.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein L F-box-like PF12937.7 KND89180.1 - 0.025 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like Tme5_EGF_like PF09064.10 KND89180.1 - 0.057 13.3 1.5 0.12 12.3 1.5 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like F-box PF00646.33 KND89180.1 - 0.19 11.6 2.3 1 9.3 0.0 2.9 3 0 0 3 3 3 0 F-box domain Bac_rhamnosid6H PF17389.2 KND89181.1 - 2.7e-16 59.8 0.4 1.5e-15 57.3 0.2 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KND89181.1 - 2.1e-10 40.3 0.1 4.4e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 KND89181.1 - 0.0024 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KND89181.1 - 0.0074 16.3 0.1 0.043 13.8 0.0 2.3 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain GDE_C PF06202.14 KND89181.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase ICL PF00463.21 KND89182.1 - 1.8e-187 624.0 0.0 2.1e-187 623.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Citrate_synt PF00285.21 KND89183.1 - 7.5e-96 321.3 0.0 9.2e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Glyco_hydro_16 PF00722.21 KND89184.1 - 1.4e-40 138.6 1.8 1.4e-40 138.6 1.8 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Pkinase PF00069.25 KND89186.1 - 4.7e-26 91.7 0.0 3.1e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89186.1 - 4.2e-08 32.8 0.0 0.0067 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ras PF00071.22 KND89187.1 - 3.4e-50 169.8 0.0 4.3e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND89187.1 - 2.8e-20 72.7 0.0 5.9e-20 71.7 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND89187.1 - 1.9e-06 27.4 0.0 4.1e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND89187.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND89187.1 - 0.019 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 KND89187.1 - 0.059 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CWC25 PF12542.8 KND89188.1 - 1.5e-26 93.3 0.9 1.5e-26 93.3 0.9 4.0 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 KND89188.1 - 3e-12 46.5 3.7 3e-12 46.5 3.7 4.6 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PAP_assoc PF03828.19 KND89190.1 - 1.2e-16 60.7 0.3 2.9e-16 59.4 0.3 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KND89190.1 - 0.17 12.2 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain AhpC-TSA_2 PF13911.6 KND89191.1 - 9.4e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 KND89191.1 - 0.0023 17.7 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin Peptidase_S8 PF00082.22 KND89193.1 - 6.7e-37 127.4 6.9 1e-36 126.7 6.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND89193.1 - 5.4e-20 71.8 0.2 1.1e-19 70.8 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 NADHdh_A3 PF14987.6 KND89194.1 - 0.038 14.3 0.1 0.046 14.0 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DDOST_48kD PF03345.14 KND89195.1 - 2e-143 478.2 0.0 3.1e-143 477.6 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Beach PF02138.18 KND89195.1 - 1.8e-119 398.2 0.0 3.2e-119 397.4 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 KND89195.1 - 4.4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 KND89195.1 - 2.2e-09 37.6 0.0 4.5e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 KND89195.1 - 0.00017 22.3 0.7 0.85 10.6 0.1 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4704 PF15787.5 KND89195.1 - 0.0017 17.6 0.0 0.0068 15.7 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4704) TFIIA PF03153.13 KND89196.1 - 0.0035 17.4 16.1 0.0035 17.4 16.1 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 KND89196.1 - 0.031 13.0 12.0 0.042 12.6 12.0 1.2 1 0 0 1 1 1 0 Caldesmon DUF4746 PF15928.5 KND89196.1 - 0.063 12.7 6.5 0.088 12.2 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 KND89196.1 - 0.63 8.8 11.6 0.9 8.2 11.6 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 KND89196.1 - 0.85 7.8 16.7 1.2 7.4 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 KND89196.1 - 3.5 5.4 10.2 4.4 5.1 10.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 KND89196.1 - 5.1 7.1 9.1 9.6 6.2 9.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 KND89196.1 - 5.9 6.8 13.1 9.5 6.2 13.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A LMBR1 PF04791.16 KND89196.1 - 6.6 5.5 4.3 8.1 5.2 4.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SE PF08491.10 KND89197.1 - 1.8e-15 56.8 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase EcKinase PF02958.20 KND89198.1 - 0.096 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PAF-AH_p_II PF03403.13 KND89199.1 - 2.7e-29 101.8 0.0 3.9e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KND89199.1 - 0.0053 15.7 0.0 0.24 10.3 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KND89199.1 - 0.0097 15.2 0.4 2.4 7.3 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KND89199.1 - 0.023 14.5 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KND89199.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Mannosidase_ig PF17786.1 KND89200.1 - 1.8e-14 54.1 0.4 6.4e-14 52.3 0.4 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KND89200.1 - 3e-12 46.1 0.0 7.6e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KND89200.1 - 2.1e-08 34.8 0.0 4.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 TPR_10 PF13374.6 KND89201.1 - 2.8e-17 62.0 0.0 1.6e-08 34.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND89201.1 - 5.4e-11 42.6 0.0 5.7e-10 39.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat NB-ARC PF00931.22 KND89201.1 - 1.4e-05 24.4 0.0 2.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 KND89201.1 - 0.0013 18.2 0.1 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KND89201.1 - 0.0065 17.1 0.1 0.021 15.5 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 KND89201.1 - 0.07 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND89201.1 - 0.2 12.0 6.0 0.031 14.7 1.5 2.1 2 1 0 2 2 2 0 AAA ATPase domain zf-3CxxC PF13695.6 KND89202.1 - 1.3e-19 70.5 0.3 1.5e-19 70.3 0.3 1.0 1 0 0 1 1 1 1 Zinc-binding domain zf-tcix PF14952.6 KND89202.1 - 8.7 6.1 9.6 3.6 7.3 0.1 2.6 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding 2OG-FeII_Oxy_3 PF13640.6 KND89203.1 - 8.6e-08 33.0 0.1 1.7e-07 32.0 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chromo PF00385.24 KND89204.1 - 3.2e-10 39.8 1.1 0.00097 19.0 0.0 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain SWIRM-assoc_2 PF16496.5 KND89204.1 - 5.6 5.7 10.7 1.6 7.5 0.0 2.7 3 0 0 3 3 3 0 SWIRM-associated domain at the N-terminal HTH_57 PF18679.1 KND89205.1 - 0.14 12.5 0.0 0.15 12.4 0.0 1.0 1 0 0 1 1 1 0 ThcOx helix turn helix domain Asparaginase_II PF06089.12 KND89207.1 - 3e-56 190.8 0.8 3.4e-56 190.6 0.8 1.0 1 0 0 1 1 1 1 L-asparaginase II Asparaginase_II PF06089.12 KND89208.1 - 1.2e-42 146.1 0.2 1.3e-42 146.0 0.2 1.0 1 0 0 1 1 1 1 L-asparaginase II CSD2 PF17876.1 KND89208.1 - 0.18 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Cold shock domain EMC1_C PF07774.13 KND89211.1 - 2.4e-66 223.5 0.0 4.3e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KND89211.1 - 9.2e-20 71.2 7.9 1.3e-14 54.4 2.4 3.0 2 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 KND89211.1 - 0.0088 15.9 10.7 0.99 9.4 0.0 5.7 6 0 0 6 6 6 2 PQQ enzyme repeat PQQ_3 PF13570.6 KND89211.1 - 0.17 12.4 5.2 33 5.1 0.2 5.1 4 0 0 4 4 4 0 PQQ-like domain HATPase_c_3 PF13589.6 KND89214.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SLC35F PF06027.12 KND89216.1 - 7.1e-99 331.1 14.8 9e-99 330.8 14.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KND89216.1 - 3e-10 39.6 0.3 5.5e-10 38.7 0.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KND89216.1 - 3.4e-08 33.8 28.3 0.0002 21.5 7.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1427 PF07235.11 KND89216.1 - 0.17 11.9 0.3 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Metallophos PF00149.28 KND89218.1 - 1.7e-10 41.7 2.7 4.7e-10 40.3 1.2 2.3 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KND89218.1 - 0.0044 17.2 0.0 0.021 15.0 0.0 2.0 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain B12-binding PF02310.19 KND89218.1 - 0.11 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain adh_short PF00106.25 KND89220.1 - 2.5e-42 144.6 1.5 3.2e-42 144.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND89220.1 - 7.1e-40 137.0 4.6 8.4e-40 136.8 4.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND89220.1 - 4.8e-11 42.9 2.1 6.8e-11 42.4 2.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND89220.1 - 0.0017 17.8 0.3 0.0027 17.2 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND89220.1 - 0.0022 17.2 0.5 0.0033 16.6 0.5 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Transketolase_C PF02780.20 KND89220.1 - 0.0055 16.6 0.8 0.022 14.6 0.1 2.2 2 1 0 2 2 2 1 Transketolase, C-terminal domain HSP33 PF01430.19 KND89220.1 - 0.022 14.2 0.2 0.031 13.7 0.2 1.2 1 0 0 1 1 1 0 Hsp33 protein GDP_Man_Dehyd PF16363.5 KND89220.1 - 0.044 13.2 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND89220.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KND89220.1 - 0.12 11.6 1.0 0.44 9.7 0.4 2.3 2 1 0 2 2 2 0 Male sterility protein DUF3494 PF11999.8 KND89221.1 - 3e-41 141.4 18.3 5.4e-41 140.5 18.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3494) Dicer_N PF17895.1 KND89221.1 - 0.077 12.8 3.0 0.14 12.0 0.2 2.2 1 1 1 2 2 2 0 Giardia Dicer N-terminal domain ABC_tran PF00005.27 KND89223.1 - 3.6e-08 34.0 0.0 4.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND89223.1 - 0.0016 17.9 0.1 0.0016 17.9 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KND89223.1 - 0.29 11.4 2.3 3.4 8.0 2.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ACT_3 PF10000.9 KND89225.1 - 2.9e-13 49.5 0.0 6.8e-13 48.3 0.0 1.7 1 1 0 1 1 1 1 ACT domain HTH_29 PF13551.6 KND89225.1 - 5.9e-08 32.6 0.1 1.2e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KND89225.1 - 0.0023 17.7 0.1 0.0042 16.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 KND89225.1 - 0.0024 18.0 0.5 0.0046 17.1 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 KND89225.1 - 0.012 16.2 0.1 0.038 14.6 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain ACT_7 PF13840.6 KND89225.1 - 0.063 13.1 0.0 0.18 11.6 0.0 1.7 1 1 1 2 2 2 0 ACT domain MarR_2 PF12802.7 KND89225.1 - 0.064 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 MarR family Ribosomal_60s PF00428.19 KND89225.1 - 8 7.1 13.8 25 5.6 11.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAYSvFN PF10260.9 KND89226.1 - 0.69 9.9 0.1 0.69 9.9 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) BTB PF00651.31 KND89229.1 - 5.9e-19 68.3 0.5 9.4e-19 67.7 0.5 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-HIT PF04438.16 KND89229.1 - 0.0025 17.7 5.2 0.11 12.4 0.7 2.5 2 0 0 2 2 2 2 HIT zinc finger TF_Zn_Ribbon PF08271.12 KND89229.1 - 0.022 14.3 0.9 0.049 13.2 0.9 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_9 PF13901.6 KND89229.1 - 0.12 12.3 4.5 0.24 11.4 4.5 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Ribosomal_L37ae PF01780.19 KND89229.1 - 0.14 12.2 1.7 0.98 9.6 2.3 2.0 2 0 0 2 2 2 0 Ribosomal L37ae protein family HypA PF01155.19 KND89229.1 - 0.25 11.4 2.0 0.3 11.1 0.6 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 KND89229.1 - 0.36 10.6 2.6 10 5.9 0.5 2.7 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 KND89229.1 - 0.37 10.9 4.3 4.2 7.6 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS91 PF14319.6 KND89229.1 - 0.43 10.7 7.4 0.4 10.7 5.7 1.9 2 1 0 2 2 2 0 Transposase zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KND89229.1 - 0.61 10.1 5.1 2.1 8.4 5.2 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 KND89229.1 - 0.71 9.4 4.8 6.9 6.2 4.8 2.4 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KND89229.1 - 1.3 9.1 6.7 15 5.7 6.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin_2 PF18073.1 KND89229.1 - 4.4 7.1 7.1 7.5 6.4 1.1 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain OrfB_Zn_ribbon PF07282.11 KND89229.1 - 5.1 7.1 6.9 5 7.1 4.6 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 KND89229.1 - 6.6 6.7 11.3 7.8 6.5 0.7 2.9 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Globin PF00042.22 KND89230.1 - 9.8e-12 45.4 0.1 1.9e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 KND89230.1 - 6.9e-10 39.6 0.0 1.3e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 KND89230.1 - 9.1e-05 22.4 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Protoglobin FAD_binding_6 PF00970.24 KND89230.1 - 0.0069 16.7 0.0 0.03 14.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KND89230.1 - 0.029 14.5 0.0 0.15 12.1 0.0 2.0 1 1 1 2 2 2 0 Ferric reductase NAD binding domain MFS_1 PF07690.16 KND89231.1 - 6.6e-29 100.9 21.8 6.6e-29 100.9 21.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89231.1 - 2.5e-06 26.6 10.7 2.9e-06 26.4 2.3 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KND89231.1 - 0.0068 14.9 1.1 0.0068 14.9 1.1 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector Folate_carrier PF01770.18 KND89231.1 - 0.098 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF5484 PF17583.2 KND89231.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Acetyltransf_3 PF13302.7 KND89232.1 - 1.5e-14 54.8 0.0 2.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND89232.1 - 4.4e-05 23.7 0.0 6.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KND89232.1 - 0.0024 18.0 0.0 0.0032 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 KND89233.1 - 1.4e-11 43.8 0.7 2.1e-11 43.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KND89234.1 - 1.1e-62 212.3 0.0 1.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.6 KND89235.1 - 2e-18 67.1 0.0 3.3e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KND89235.1 - 1.1e-17 64.6 0.1 1.1e-17 64.6 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KND89235.1 - 7.3e-14 51.9 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 KND89235.1 - 4.2e-13 48.7 0.6 1.4e-09 37.0 0.1 3.0 1 1 2 3 3 3 2 Cellulose synthase Glyco_transf_21 PF13506.6 KND89235.1 - 2e-12 46.9 0.0 3.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 KND89235.1 - 8.1e-05 21.4 0.2 0.007 15.0 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_hydro_81 PF03639.13 KND89236.1 - 0.06 12.5 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain Pkinase PF00069.25 KND89237.1 - 4.1e-28 98.5 0.0 2e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND89237.1 - 6e-09 35.6 0.0 0.00054 19.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KND89237.1 - 0.00034 20.6 0.1 0.00096 19.1 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND89237.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND89237.1 - 0.1 11.4 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KND89237.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PhyH PF05721.13 KND89238.1 - 2.9e-10 40.8 0.1 5.9e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.21 KND89239.1 - 1.5e-121 406.4 31.8 1.6e-121 406.2 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND89239.1 - 2.4e-32 112.3 36.0 2.9e-32 112.1 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.23 KND89240.1 - 2.5e-10 40.7 0.0 4.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KND89240.1 - 9.1e-06 25.7 5.9 1.8e-05 24.8 5.9 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ank_2 PF12796.7 KND89241.1 - 1.4e-62 208.3 6.0 4.9e-19 68.7 0.0 5.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 KND89241.1 - 1.5e-44 148.5 14.5 2.2e-06 27.8 0.0 10.5 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 KND89241.1 - 7.3e-44 147.6 2.1 2.2e-14 53.6 0.0 9.1 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND89241.1 - 1.5e-40 136.7 6.3 3e-09 37.0 0.0 7.3 4 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND89241.1 - 4.4e-34 112.7 0.9 0.00012 22.2 0.0 10.6 11 0 0 11 11 11 5 Ankyrin repeat DUF4988 PF16378.5 KND89241.1 - 0.0027 17.4 0.0 0.11 12.1 0.0 3.3 3 2 1 4 4 4 1 Domain of unknown function RVP PF00077.20 KND89241.1 - 0.16 12.3 4.9 8.7 6.7 0.0 4.2 4 2 1 5 5 5 0 Retroviral aspartyl protease Fungal_trans PF04082.18 KND89243.1 - 9.3e-10 38.0 0.4 1.4e-09 37.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89243.1 - 1.6e-09 37.7 7.9 3.2e-09 36.8 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BDM PF10684.9 KND89244.1 - 0.052 13.9 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Putative biofilm-dependent modulation protein MFS_1 PF07690.16 KND89245.1 - 2.9e-56 190.9 84.5 7e-46 156.8 54.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.26 KND89246.1 - 4.3e-12 46.1 0.3 3.2e-11 43.3 0.1 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND89246.1 - 1.7e-07 32.4 0.0 3.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND89246.1 - 7e-06 25.9 0.0 7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KND89246.1 - 0.0041 16.6 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND89246.1 - 0.09 12.3 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family FAD_binding_6 PF00970.24 KND89247.1 - 5.7e-07 29.8 0.0 1.4e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND89247.1 - 9.8e-07 29.4 0.0 2.7e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 KND89247.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 KND89247.1 - 0.0029 17.5 0.0 0.006 16.5 0.0 1.5 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 KND89247.1 - 0.0044 17.2 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain TPR_MLP1_2 PF07926.12 KND89248.1 - 0.017 15.2 1.4 0.057 13.5 1.4 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 KND89248.1 - 0.075 13.1 4.4 0.042 13.9 2.0 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SYCE1 PF15233.6 KND89248.1 - 0.11 12.6 1.6 0.23 11.5 1.6 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 CdvA PF18822.1 KND89248.1 - 0.16 11.8 4.0 0.33 10.8 0.8 2.9 3 0 0 3 3 3 0 CdvA-like coiled-coil domain DUF5082 PF16888.5 KND89248.1 - 1.2 9.4 8.1 1.3 9.3 2.4 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 KND89248.1 - 2.2 7.5 7.7 1.1 8.5 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KND89248.1 - 3 8.0 8.3 2.7 8.2 3.9 3.0 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KND89249.1 - 8e-45 149.9 25.8 2e-08 34.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND89249.1 - 3.2e-14 53.0 3.1 0.049 13.9 0.0 6.0 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND89249.1 - 6.7e-08 31.6 9.6 0.11 11.1 0.1 4.9 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KND89249.1 - 1.2e-07 31.0 6.8 0.00046 19.3 0.8 4.0 1 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NAGLU PF05089.12 KND89250.1 - 2.2e-129 431.2 9.4 4.2e-129 430.3 9.4 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 KND89250.1 - 2.5e-74 250.2 7.6 4e-74 249.5 7.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 KND89250.1 - 3.2e-18 65.3 0.0 7.5e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain ASFV_p27 PF06556.11 KND89250.1 - 0.16 12.1 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 IAP-like protein p27 C-terminus Spc7 PF08317.11 KND89251.1 - 2.2e-05 23.5 26.7 0.0015 17.5 15.8 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 KND89251.1 - 0.00041 20.5 28.6 0.0016 18.6 17.3 2.5 1 1 1 2 2 2 1 Tropomyosin like DUF4527 PF15030.6 KND89251.1 - 0.0051 16.3 6.3 0.028 13.9 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4527) SLT_beta PF02258.16 KND89251.1 - 0.08 13.0 0.3 2.6 8.2 0.1 3.0 4 0 0 4 4 4 0 Shiga-like toxin beta subunit Fib_alpha PF08702.10 KND89251.1 - 0.2 11.8 17.3 0.26 11.5 1.0 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KND89251.1 - 0.86 9.0 28.2 0.22 10.9 13.0 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Gly_acyl_tr_N PF06021.11 KND89251.1 - 1.1 9.3 6.0 2.3 8.3 6.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase BST2 PF16716.5 KND89251.1 - 3.2 8.4 30.2 0.62 10.7 4.6 3.6 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 CLZ PF16526.5 KND89251.1 - 3.9 7.9 22.9 0.045 14.1 2.4 4.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NDUF_B5 PF09781.9 KND89252.1 - 0.065 12.8 0.4 0.073 12.6 0.4 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit APH PF01636.23 KND89253.1 - 0.0044 17.0 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KND89253.1 - 0.005 15.7 0.0 0.0056 15.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 KND89253.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Sigma70_ner PF04546.13 KND89253.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region Abhydrolase_2 PF02230.16 KND89255.1 - 2.7e-22 79.7 0.0 3.3e-15 56.5 0.0 2.0 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KND89255.1 - 9.5e-09 35.0 0.0 4.9e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KND89255.1 - 0.00076 19.4 0.0 0.00098 19.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KND89255.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KND89255.1 - 0.0013 19.4 0.0 0.0017 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND89255.1 - 0.0085 15.4 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Isy1 PF06246.12 KND89257.1 - 2.8e-91 305.6 1.2 3.4e-91 305.3 1.2 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 KND89257.1 - 0.041 13.9 1.0 0.059 13.4 0.0 1.7 2 0 0 2 2 2 0 YolD-like protein Sigma70_ner PF04546.13 KND89258.1 - 0.0065 16.4 1.6 0.28 11.0 0.2 2.2 2 0 0 2 2 2 1 Sigma-70, non-essential region bZIP_1 PF00170.21 KND89258.1 - 0.016 15.3 1.4 0.021 14.9 0.3 1.7 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 KND89258.1 - 0.069 13.8 2.3 0.77 10.4 0.2 2.3 2 0 0 2 2 2 0 Initiation control protein YabA SlyX PF04102.12 KND89258.1 - 0.09 13.4 0.8 0.09 13.4 0.8 2.1 2 0 0 2 2 2 0 SlyX DUF4140 PF13600.6 KND89258.1 - 0.12 12.9 3.7 0.2 12.1 0.4 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 KND89258.1 - 0.13 12.7 0.7 0.6 10.6 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 KND89258.1 - 0.36 10.5 6.6 0.081 12.6 0.6 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 KND89258.1 - 0.4 10.5 7.5 0.13 12.0 2.5 2.5 2 0 0 2 2 2 0 Septum formation initiator Tropomyosin_1 PF12718.7 KND89258.1 - 0.49 10.5 6.0 0.21 11.7 0.6 2.1 2 0 0 2 2 2 0 Tropomyosin like Striatin PF08232.12 KND89258.1 - 0.53 10.9 5.2 0.11 13.1 1.0 2.0 2 0 0 2 2 2 0 Striatin family EzrA PF06160.12 KND89258.1 - 0.72 8.0 2.4 0.46 8.6 0.4 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA ATG16 PF08614.11 KND89258.1 - 0.75 10.0 8.0 0.04 14.1 1.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 KND89258.1 - 1 9.8 4.1 0.53 10.8 1.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB GrpE PF01025.19 KND89258.1 - 1.4 8.6 7.2 0.91 9.2 1.3 2.2 2 0 0 2 2 2 0 GrpE Spc7 PF08317.11 KND89258.1 - 2.5 6.9 5.5 0.85 8.4 0.5 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein PLA2_B PF01735.18 KND89261.1 - 6.5e-173 575.6 0.1 7.6e-173 575.4 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Atg14 PF10186.9 KND89262.1 - 0.19 10.8 5.5 0.3 10.1 5.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Borrelia_P83 PF05262.11 KND89262.1 - 0.31 9.5 2.8 0.46 8.9 2.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TEBP_beta PF07404.11 KND89262.1 - 0.34 10.2 2.0 0.5 9.7 2.0 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) GFO_IDH_MocA PF01408.22 KND89263.1 - 9.3e-26 91.0 0.1 1.4e-25 90.4 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KND89263.1 - 2.5e-11 43.6 0.0 4.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KND89263.1 - 8.4e-07 29.7 0.2 2.4e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KND89263.1 - 0.0011 19.3 0.0 0.0028 18.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KND89263.1 - 0.052 13.8 0.0 0.098 12.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KND89263.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KND89263.1 - 0.059 14.0 0.1 0.2 12.3 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 KND89263.1 - 0.066 13.9 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain AlaDh_PNT_N PF05222.15 KND89264.1 - 6.8e-18 65.3 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KND89264.1 - 0.00036 19.9 0.0 0.0014 18.0 0.0 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Zeta_toxin PF06414.12 KND89264.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MFS_1 PF07690.16 KND89265.1 - 4e-34 118.1 30.8 5.8e-34 117.6 30.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC12 PF06645.13 KND89265.1 - 0.05 13.7 2.8 1 9.5 0.0 3.5 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GTP_cyclohydroI PF01227.22 KND89266.1 - 7.4e-73 243.8 0.3 9.6e-73 243.4 0.3 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KND89266.1 - 0.006 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein NAD_kinase PF01513.21 KND89267.1 - 2.6e-44 151.6 0.0 5.4e-44 150.5 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KND89267.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 KND89268.1 - 2.2e-27 95.3 0.0 3.3e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KND89268.1 - 1.5e-11 44.2 0.1 2.7e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NLRC4_HD2 PF17776.1 KND89268.1 - 0.24 11.9 0.0 0.53 10.8 0.0 1.5 1 0 0 1 1 1 0 NLRC4 helical domain HD2 LIDHydrolase PF10230.9 KND89269.1 - 3.1e-47 161.4 0.0 3.9e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KND89269.1 - 0.00017 22.3 5.5 0.00022 21.9 5.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND89269.1 - 0.015 14.5 0.0 0.11 11.8 0.0 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 CFEM PF05730.11 KND89270.1 - 1e-12 47.9 11.7 1.7e-12 47.3 11.7 1.3 1 0 0 1 1 1 1 CFEM domain DUF2845 PF11006.8 KND89270.1 - 0.035 14.2 0.7 0.06 13.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) TPR_2 PF07719.17 KND89272.1 - 6.6e-10 38.3 2.1 0.00071 19.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND89272.1 - 2.5e-06 27.0 0.1 0.12 12.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND89272.1 - 9.4e-05 22.9 0.1 0.0026 18.2 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND89272.1 - 0.00026 20.9 0.2 0.0062 16.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND89272.1 - 0.00028 21.1 0.5 0.037 14.3 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND89272.1 - 0.0018 18.9 2.9 0.034 14.8 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND89272.1 - 0.028 14.4 0.5 35 4.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND89272.1 - 0.054 14.3 8.2 0.067 14.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND89272.1 - 0.067 13.1 4.2 5.6 7.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND89272.1 - 0.37 11.5 2.2 7.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BAG PF02179.16 KND89273.1 - 5.2e-21 74.9 0.1 1.3e-20 73.6 0.1 1.7 1 0 0 1 1 1 1 BAG domain Ribosomal_L13 PF00572.18 KND89273.1 - 2e-10 41.0 0.0 6.4e-09 36.1 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 ubiquitin PF00240.23 KND89273.1 - 0.00011 21.9 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 KND89273.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DSBA PF01323.20 KND89273.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Chalcone_2 PF16035.5 KND89274.1 - 1e-78 263.8 0.0 1.5e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KND89274.1 - 0.0037 17.4 0.0 0.11 12.6 0.1 2.2 1 1 1 2 2 2 1 Chalcone isomerase-like Aldedh PF00171.22 KND89275.1 - 1.3e-142 475.6 0.0 1.5e-142 475.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cas_Cmr5 PF09701.10 KND89275.1 - 0.081 13.2 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr5) Melibiase PF02065.18 KND89276.1 - 5.5e-143 476.1 0.0 7.3e-143 475.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KND89276.1 - 2.1e-77 260.1 0.0 3.1e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 KND89276.1 - 5.2e-20 71.7 0.0 1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain LRR_6 PF13516.6 KND89276.1 - 2.6e-15 55.1 18.3 0.035 14.2 0.0 10.4 11 0 0 11 11 11 5 Leucine Rich repeat F-box-like PF12937.7 KND89276.1 - 3.8e-12 45.9 0.9 1.5e-11 43.9 0.5 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KND89276.1 - 5.1e-07 29.9 10.0 3.6 8.1 0.0 6.6 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.33 KND89276.1 - 3.8e-05 23.4 0.2 0.00012 21.9 0.2 1.9 1 0 0 1 1 1 1 F-box domain GHL10 PF02638.15 KND89276.1 - 0.00023 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Ammonium_transp PF00909.21 KND89277.1 - 2.3e-118 395.4 23.2 2.7e-118 395.2 23.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pept_tRNA_hydro PF01195.19 KND89278.1 - 6.1e-30 104.4 0.0 7.2e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DCP1 PF06058.13 KND89279.1 - 3.4e-33 114.0 0.0 4.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family HTH_Tnp_Tc5 PF03221.16 KND89279.1 - 0.073 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain BAR PF03114.18 KND89280.1 - 2.1e-65 220.7 4.5 2.6e-65 220.4 4.5 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KND89280.1 - 0.0039 17.9 0.1 0.019 15.7 0.0 2.2 2 1 1 3 3 3 1 CP12 domain tRNA-synt_2 PF00152.20 KND89281.1 - 5.5e-81 272.1 0.0 7.3e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND89281.1 - 8e-07 29.0 0.1 1.6e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain ADP_ribosyl_GH PF03747.14 KND89282.1 - 3.4e-58 197.7 8.3 4e-58 197.5 8.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sec23_trunk PF04811.15 KND89283.1 - 6.4e-49 166.7 0.0 1.4e-48 165.6 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KND89283.1 - 1.1e-24 86.2 0.1 2e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KND89283.1 - 9.7e-18 64.7 0.0 1.7e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KND89283.1 - 2.3e-15 56.4 4.6 4.8e-15 55.3 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KND89283.1 - 1.2e-06 28.4 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2263 PF10021.9 KND89284.1 - 4.1e-07 30.5 0.0 5.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Linker_histone PF00538.19 KND89286.1 - 3.7e-27 94.5 0.1 9.4e-27 93.2 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family Toxin_trans PF07952.12 KND89286.1 - 0.053 12.6 0.2 0.074 12.1 0.2 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain LrgB PF04172.16 KND89288.1 - 3.4e-46 157.5 15.0 3.4e-46 157.5 15.0 2.8 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.14 KND89288.1 - 0.0024 17.8 8.1 0.0024 17.8 8.1 2.6 2 1 0 2 2 2 1 LrgA family HemY_N PF07219.13 KND89288.1 - 0.46 10.7 0.1 0.46 10.7 0.1 3.5 4 0 0 4 4 4 0 HemY protein N-terminus DUF3437 PF11919.8 KND89289.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Asp PF00026.23 KND89290.1 - 5.7e-108 361.0 0.0 6.8e-108 360.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND89290.1 - 4.4e-15 56.4 1.1 8.6e-13 48.9 1.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND89290.1 - 0.00012 22.6 0.0 1.3 9.8 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KND89290.1 - 0.0017 18.2 0.0 0.021 14.6 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KND89290.1 - 0.01 16.4 0.0 8.1 7.1 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease BDHCT_assoc PF16204.5 KND89290.1 - 0.2 11.3 0.1 0.31 10.7 0.1 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein AAA PF00004.29 KND89291.1 - 5.1e-45 153.1 0.4 1.7e-44 151.4 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KND89291.1 - 1.4e-10 41.0 0.1 8.8e-10 38.4 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KND89291.1 - 9.3e-09 35.4 0.2 3.3e-08 33.6 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND89291.1 - 7.7e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KND89291.1 - 2.5e-07 31.2 0.5 4.2e-05 24.0 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KND89291.1 - 4.6e-06 26.0 0.0 9.7e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KND89291.1 - 5e-05 23.6 1.3 0.0092 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 KND89291.1 - 0.00037 20.3 0.0 0.00081 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KND89291.1 - 0.00047 19.9 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KND89291.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND89291.1 - 0.0012 19.3 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KND89291.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KND89291.1 - 0.0015 18.1 0.1 0.0081 15.7 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KND89291.1 - 0.0017 18.7 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KND89291.1 - 0.0021 18.1 0.0 0.025 14.6 0.0 2.1 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KND89291.1 - 0.0028 17.6 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 KND89291.1 - 0.0029 17.6 0.1 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND89291.1 - 0.0055 16.6 0.4 0.13 12.2 0.0 3.0 4 0 0 4 4 4 1 NACHT domain AAA_3 PF07726.11 KND89291.1 - 0.0079 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KND89291.1 - 0.0097 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KND89291.1 - 0.01 16.0 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KND89291.1 - 0.013 15.3 1.3 0.015 15.0 0.1 1.9 2 1 0 2 2 1 0 AAA domain TniB PF05621.11 KND89291.1 - 0.014 14.8 0.0 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Viral_Hsp90 PF03225.14 KND89291.1 - 0.017 13.7 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue IstB_IS21 PF01695.17 KND89291.1 - 0.021 14.6 0.2 0.052 13.3 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AFG1_ATPase PF03969.16 KND89291.1 - 0.021 13.7 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 KND89291.1 - 0.026 14.2 0.2 0.059 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND89291.1 - 0.047 13.5 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KND89291.1 - 0.06 13.2 1.3 0.36 10.7 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KND89291.1 - 0.07 12.5 1.3 0.63 9.3 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 KND89291.1 - 0.076 13.5 0.0 6.2 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KND89291.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KND89291.1 - 0.11 12.1 0.2 1.6 8.4 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KND89291.1 - 0.15 11.6 1.8 0.3 10.6 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 KND89291.1 - 0.16 12.3 0.1 0.46 10.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KND89291.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Folliculin PF11704.8 KND89292.1 - 5.6e-58 195.9 0.0 1e-57 195.0 0.0 1.4 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Acyl-CoA_dh_1 PF00441.24 KND89293.1 - 1.1e-42 145.8 0.2 1.5e-42 145.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND89293.1 - 7.1e-22 78.2 0.0 1.3e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND89293.1 - 2.7e-20 72.4 0.1 5.2e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 KND89293.1 - 6.5e-20 71.1 0.3 1.2e-19 70.2 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 KND89293.1 - 8.3e-09 35.8 0.0 1.3e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.29 KND89294.1 - 2.3e-43 148.0 0.0 3.5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND89294.1 - 4.3e-28 97.9 0.7 2.9e-27 95.2 0.5 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND89294.1 - 0.00044 20.3 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KND89294.1 - 0.087 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit WSC PF01822.19 KND89295.1 - 1.8e-11 44.1 7.5 1.8e-11 44.1 7.5 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 KND89295.1 - 8.3e-07 28.3 2.7 1.7e-06 27.3 2.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 KND89295.1 - 0.00065 19.8 0.5 0.0025 17.9 0.2 1.9 2 0 0 2 2 2 1 Podoplanin MGC-24 PF05283.11 KND89295.1 - 0.0013 19.2 0.3 0.0013 19.2 0.3 1.9 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 KND89295.1 - 0.0069 16.6 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 Glycophorin A Pex14_N PF04695.13 KND89295.1 - 0.048 14.3 0.8 0.048 14.3 0.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Trp_oprn_chp PF09534.10 KND89295.1 - 0.075 12.8 0.5 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4448 PF14610.6 KND89295.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2076 PF09849.9 KND89295.1 - 0.5 10.4 4.3 0.15 12.1 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Gram_pos_anchor PF00746.21 KND89295.1 - 2.8 8.0 9.1 0.098 12.6 2.5 2.0 2 1 1 3 3 3 0 LPXTG cell wall anchor motif XPG_I PF00867.18 KND89296.1 - 1.7e-30 105.2 0.0 1.7e-30 105.2 0.0 2.2 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.17 KND89296.1 - 3.9e-27 94.7 0.0 1.2e-26 93.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KND89296.1 - 1.3e-05 25.7 1.2 4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KND89296.1 - 0.094 13.3 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Mis14 PF08641.12 KND89297.1 - 2e-14 54.1 0.1 5e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF155 PF02582.14 KND89299.1 - 1.1e-46 159.2 0.0 1.5e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 KND89299.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cupin CRAL_TRIO PF00650.20 KND89300.1 - 4.7e-35 120.6 0.0 7.8e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND89300.1 - 6.4e-07 29.5 0.1 1.9e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KND89300.1 - 0.004 17.3 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Aldo_ket_red PF00248.21 KND89302.1 - 4.1e-47 160.8 0.1 7.4e-45 153.4 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Caskin1-CID PF16600.5 KND89302.1 - 0.0085 16.7 0.1 0.016 15.8 0.1 1.4 1 0 0 1 1 1 1 Caskin1 CASK-interaction domain Death PF00531.22 KND89302.1 - 0.012 15.7 0.0 13 6.1 0.0 3.2 3 0 0 3 3 3 0 Death domain LysM PF01476.20 KND89302.1 - 0.17 12.0 0.5 0.4 10.8 0.1 1.9 2 0 0 2 2 2 0 LysM domain Pyridoxal_deC PF00282.19 KND89303.1 - 5.4e-67 226.1 0.0 1.3e-64 218.3 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KND89303.1 - 5.8e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND89303.1 - 0.00065 19.1 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 KND89304.1 - 1.3e-39 135.4 0.0 2.1e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KND89304.1 - 1.5e-11 44.6 0.1 3.2e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND89304.1 - 0.00068 19.1 0.0 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND89304.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase T_hemolysin PF12261.8 KND89304.1 - 0.032 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin PRK PF00485.18 KND89304.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 KND89304.1 - 0.19 11.2 0.1 2.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AMMECR1 PF01871.17 KND89305.1 - 1.5e-44 151.6 0.0 1.8e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Crystall PF00030.19 KND89305.1 - 0.075 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF4006 PF13179.6 KND89306.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) JAB PF01398.21 KND89307.1 - 1.5e-13 50.8 0.0 2.6e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KND89307.1 - 2.2e-07 31.0 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KND89307.1 - 7.7e-06 25.7 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain An_peroxidase PF03098.15 KND89308.1 - 2.1e-46 158.6 0.0 1.1e-32 113.4 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase NACHT_N PF17100.5 KND89309.1 - 1.1e-63 215.1 0.2 1.8e-63 214.3 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KND89309.1 - 8.1e-13 48.6 0.3 3.7e-12 46.5 0.2 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KND89309.1 - 0.015 15.6 0.0 0.063 13.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KND89309.1 - 0.017 15.5 0.1 0.084 13.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KND89309.1 - 0.025 14.9 0.0 0.089 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KND89309.1 - 0.028 14.2 1.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KND89309.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KND89309.1 - 0.23 11.5 1.3 3.4 7.7 0.1 3.1 3 1 0 3 3 3 0 AAA domain PUF PF00806.19 KND89310.1 - 4.2e-14 51.3 0.1 0.089 12.5 0.0 7.0 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat SH PF01445.17 KND89311.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein DnaJ PF00226.31 KND89312.1 - 2.3e-06 27.6 0.6 0.076 13.2 0.3 2.3 2 0 0 2 2 2 2 DnaJ domain UCH PF00443.29 KND89313.1 - 6.7e-40 137.2 0.0 1.1e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KND89313.1 - 7e-08 32.3 0.4 0.00024 21.0 0.0 3.4 3 0 0 3 3 3 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KND89313.1 - 2.5e-06 27.3 2.3 0.0048 16.5 0.1 2.9 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ECH_1 PF00378.20 KND89314.1 - 1.2e-39 136.1 0.0 1.5e-37 129.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND89314.1 - 2.8e-24 86.2 0.1 1.1e-22 81.0 0.1 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF917 PF06032.12 KND89315.1 - 2.7e-124 414.6 0.4 5.2e-124 413.6 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KND89315.1 - 5.1e-33 114.6 1.5 7.1e-31 107.5 0.0 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KND89315.1 - 3.6e-28 98.5 0.5 4e-25 88.6 0.2 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 KND89315.1 - 1.2e-05 24.9 0.4 0.0018 17.8 0.1 3.0 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 KND89315.1 - 8.4e-05 21.3 0.3 0.0017 17.0 0.0 2.4 2 0 0 2 2 2 1 MutL protein ROK PF00480.20 KND89315.1 - 0.0056 16.2 0.2 0.038 13.5 0.0 2.5 3 0 0 3 3 3 1 ROK family StbA PF06406.11 KND89315.1 - 0.011 15.0 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 StbA protein MreB_Mbl PF06723.13 KND89315.1 - 0.047 12.5 0.7 0.7 8.7 0.0 2.7 2 1 1 3 3 3 0 MreB/Mbl protein Ank_2 PF12796.7 KND89317.1 - 1.8e-21 76.5 0.0 1.9e-06 28.4 0.0 5.7 4 1 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND89317.1 - 6.4e-20 71.2 1.4 6.8e-05 23.4 0.0 8.0 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND89317.1 - 1.3e-18 66.8 4.3 0.00079 19.7 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 KND89317.1 - 1.7e-17 63.0 0.9 0.0056 17.1 0.1 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 KND89317.1 - 1.8e-17 61.6 0.1 0.032 14.8 0.0 8.3 8 0 0 8 8 8 4 Ankyrin repeat Cwf_Cwc_15 PF04889.12 KND89317.1 - 4.4 7.0 9.7 6.6 6.4 9.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_4 PF13637.6 KND89318.1 - 1.8e-15 57.1 1.0 0.0016 18.9 0.0 6.2 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KND89318.1 - 4.7e-13 48.9 8.0 0.005 17.2 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Ank_2 PF12796.7 KND89318.1 - 5.4e-10 39.7 0.4 0.23 12.1 0.0 5.9 4 3 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND89318.1 - 1.4e-07 31.2 5.3 0.081 13.5 0.0 6.9 7 2 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 KND89318.1 - 1.8e-05 24.9 2.0 11 6.5 0.0 6.0 5 2 0 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 KND89318.1 - 3.4e-05 23.7 0.0 9.2e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND89318.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 KND89318.1 - 0.18 12.1 0.1 0.37 11.2 0.1 1.5 1 0 0 1 1 1 0 PRANC domain Gpr1_Fun34_YaaH PF01184.19 KND89319.1 - 4.2e-55 186.6 20.7 6e-55 186.1 20.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2254 PF10011.9 KND89319.1 - 0.11 11.3 8.1 0.031 13.1 4.6 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) Podoplanin PF05808.11 KND89320.1 - 0.042 14.0 4.4 0.12 12.5 4.4 1.6 1 1 0 1 1 1 0 Podoplanin FeoB_associated PF12669.7 KND89320.1 - 0.1 13.0 1.4 0.16 12.4 1.4 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein HET PF06985.11 KND89321.1 - 1.2e-26 93.8 1.0 1.1e-23 84.2 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aldose_epim PF01263.20 KND89322.1 - 1.5e-62 211.6 0.0 2e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Frag1 PF10277.9 KND89323.1 - 2.4e-39 135.1 7.7 2.4e-39 135.1 7.7 3.0 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 KND89323.1 - 0.05 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4536 PF15055.6 KND89323.1 - 0.43 10.9 0.0 0.43 10.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) p450 PF00067.22 KND89324.1 - 5.1e-58 196.9 0.0 6.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_4 PF18044.1 KND89325.1 - 3.5e-09 36.3 4.9 5e-09 35.8 3.6 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 KND89325.1 - 1.1e-06 28.4 3.0 2.4e-06 27.3 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND89325.1 - 2.1e-06 27.6 8.3 4.4e-06 26.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger domain Nucleoporin_FG PF13634.6 KND89325.1 - 0.0013 19.5 127.8 0.0083 16.9 25.4 6.4 3 1 4 7 7 7 4 Nucleoporin FG repeat region Torus PF16131.5 KND89325.1 - 0.023 15.4 0.1 0.066 13.9 0.1 1.7 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 KND89325.1 - 0.17 12.4 4.4 0.39 11.3 4.4 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CsbD PF05532.12 KND89325.1 - 1.2 9.1 3.7 2.1 8.3 3.7 1.4 1 0 0 1 1 1 0 CsbD-like SPX PF03105.19 KND89326.1 - 4.5 7.1 12.1 5.8 6.7 12.1 1.2 1 0 0 1 1 1 0 SPX domain CUE PF02845.16 KND89327.1 - 1.2e-10 40.9 0.1 2.4e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF1744 PF08490.12 KND89329.1 - 8.3e-132 439.5 0.1 8.6e-130 432.9 0.1 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KND89329.1 - 4.9e-77 259.3 0.3 7.6e-77 258.7 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KND89329.1 - 5.6e-15 55.0 0.4 6.6e-12 44.9 0.4 3.5 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KND89329.1 - 1.6e-08 34.5 0.2 4.2e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KND89329.1 - 7.1e-06 26.1 0.1 2.2e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 KND89330.1 - 2.7e-38 129.8 0.1 3.9e-38 129.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CCB1 PF12046.8 KND89330.1 - 0.00036 19.9 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B Coq4 PF05019.13 KND89331.1 - 1.2e-09 37.9 0.1 0.00057 19.3 0.1 2.1 1 1 1 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 TPR_5 PF12688.7 KND89334.1 - 0.00084 19.6 2.0 0.035 14.3 0.3 3.3 2 1 1 3 3 3 1 Tetratrico peptide repeat TPR_12 PF13424.6 KND89334.1 - 0.0055 17.0 0.8 5.5 7.4 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat HD_5 PF13487.6 KND89334.1 - 0.039 14.2 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 HD domain CENP-H PF05837.12 KND89337.1 - 0.0045 17.4 1.2 0.0076 16.6 1.2 1.3 1 0 0 1 1 1 1 Centromere protein H (CENP-H) T3SS_basalb_I PF17001.5 KND89337.1 - 0.017 15.7 0.6 0.029 14.9 0.6 1.4 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI MCU PF04678.13 KND89337.1 - 0.13 12.3 0.5 0.18 11.9 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter APH PF01636.23 KND89338.1 - 0.00012 22.0 0.2 0.00012 22.0 0.2 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 KND89339.1 - 4.2e-18 65.4 0.0 1.1e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Adeno_PIX PF03955.14 KND89339.1 - 0.45 10.7 4.5 0.25 11.5 1.7 2.0 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) FAD_binding_3 PF01494.19 KND89341.1 - 1.4e-77 261.3 0.0 2.9e-77 260.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KND89341.1 - 1.9e-42 145.1 0.0 4.5e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 KND89341.1 - 0.00033 20.0 0.0 0.043 13.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KND89341.1 - 0.0047 16.1 0.0 0.048 12.7 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 KND89341.1 - 0.0086 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KND89341.1 - 0.01 15.1 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND89341.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 KND89341.1 - 0.015 15.5 0.0 0.064 13.5 0.0 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KND89341.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KND89341.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KND89341.1 - 0.068 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLP1_P PF16575.5 KND89342.1 - 4e-28 98.5 0.0 1.4e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Fungal_trans PF04082.18 KND89343.1 - 6e-16 58.3 1.5 9.8e-16 57.6 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89343.1 - 0.017 15.2 16.8 0.032 14.3 16.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.20 KND89343.1 - 0.053 13.7 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain PAP2_3 PF14378.6 KND89344.1 - 6.6e-23 81.4 13.4 1.5e-22 80.3 13.4 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 KND89344.1 - 7.9e-08 32.2 8.1 7.9e-08 32.2 8.1 2.7 1 1 2 3 3 3 1 PAP2 superfamily RNA_polI_A34 PF08208.11 KND89345.1 - 4.8e-41 141.1 5.1 4.8e-41 141.1 5.1 5.8 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Utp14 PF04615.13 KND89345.1 - 0.0014 17.3 31.1 0.0014 17.3 31.1 2.4 2 1 0 2 2 2 1 Utp14 protein PIP5K PF01504.18 KND89346.1 - 2e-102 342.1 0.2 5e-102 340.8 0.0 1.8 1 1 1 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4604 PF15377.6 KND89346.1 - 7.5 7.0 12.7 5.6 7.4 2.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Pkinase PF00069.25 KND89347.1 - 5e-71 239.2 0.0 6.2e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89347.1 - 4.5e-28 98.2 0.0 6.2e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND89347.1 - 4.4e-07 29.5 0.0 6.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KND89347.1 - 9.2e-05 21.4 0.0 0.00019 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND89347.1 - 0.00057 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KND89347.1 - 0.00059 19.2 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydantoinase_B PF02538.14 KND89348.1 - 1.1e-211 703.7 1.0 1.5e-211 703.4 1.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KND89348.1 - 2e-101 339.1 0.1 4.1e-101 338.1 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KND89348.1 - 1.1e-57 194.6 0.0 4.2e-56 189.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region 5_nucleotid_C PF02872.18 KND89349.1 - 8.2e-34 117.1 0.3 2e-33 115.8 0.1 1.8 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KND89349.1 - 4.8e-10 40.3 0.1 7.9e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adap_comp_sub PF00928.21 KND89350.1 - 1.1e-81 274.2 0.0 1.3e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND89350.1 - 3.4e-05 23.8 0.3 6.4e-05 22.9 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KND89350.1 - 0.034 13.6 0.1 0.068 12.6 0.1 1.5 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Zn_clus PF00172.18 KND89351.1 - 0.24 11.5 8.4 0.5 10.5 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 KND89352.1 - 6.8e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M28 PF04389.17 KND89353.1 - 1.2e-36 126.2 0.0 2.3e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KND89353.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 SF1-HH PF16275.5 KND89354.1 - 1.5e-43 147.7 1.7 1.5e-43 147.7 1.7 1.9 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 KND89354.1 - 2.8e-06 27.0 0.0 5.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 KH domain Peptidase_S55 PF05580.12 KND89354.1 - 0.12 12.3 0.2 1 9.3 0.2 1.9 2 0 0 2 2 2 0 SpoIVB peptidase S55 MFS_1 PF07690.16 KND89355.1 - 3.5e-31 108.4 26.7 3.5e-31 108.4 26.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND89355.1 - 3.4e-10 39.8 3.5 3.4e-10 39.8 3.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF5357 PF17310.2 KND89355.1 - 0.011 14.3 1.3 0.019 13.5 1.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5357) A_deaminase PF00962.22 KND89356.1 - 3.5e-40 138.3 0.0 5e-40 137.8 0.0 1.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF2028 PF09667.10 KND89356.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2028) Lipase_3 PF01764.25 KND89357.1 - 9.6e-18 64.4 0.0 1.6e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KND89357.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 KND89358.1 - 6.8e-11 41.7 2.4 3.1e-10 39.6 2.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89358.1 - 2.4e-10 40.4 10.6 3.8e-10 39.7 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KND89360.1 - 1.8e-29 103.4 0.3 2.3e-29 103.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KND89360.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 CsiD Amidohydro_1 PF01979.20 KND89364.1 - 4.1e-36 125.0 0.0 5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND89364.1 - 6.1e-07 29.3 0.1 8.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family MIP PF00230.20 KND89365.1 - 5.3e-47 160.4 16.6 6.5e-47 160.1 16.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DSBA PF01323.20 KND89366.1 - 1.3e-33 116.4 0.0 1.5e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KND89366.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Gti1_Pac2 PF09729.9 KND89367.1 - 1.3e-43 149.2 2.6 1.6e-36 126.1 0.2 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family PLDc_2 PF13091.6 KND89369.1 - 8.7e-19 67.7 0.0 3e-11 43.4 0.0 3.2 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KND89369.1 - 7.1e-05 22.8 0.1 0.27 11.5 0.1 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif Prefoldin_2 PF01920.20 KND89370.1 - 2.2e-19 69.3 12.6 2.8e-19 69.0 12.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.11 KND89370.1 - 0.011 14.7 7.7 0.014 14.2 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3K_P85_iSH2 PF16454.5 KND89370.1 - 0.012 15.3 5.8 0.03 13.9 1.5 2.1 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fez1 PF06818.15 KND89370.1 - 0.017 15.6 6.9 0.045 14.2 1.1 2.1 2 0 0 2 2 2 0 Fez1 COG5 PF10392.9 KND89370.1 - 0.024 14.8 2.6 1.2 9.3 0.2 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Prefoldin_3 PF13758.6 KND89370.1 - 0.026 14.5 3.5 0.039 14.0 3.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit Ndr PF03096.14 KND89370.1 - 0.036 12.8 0.1 0.036 12.8 0.1 1.2 1 1 0 1 1 1 0 Ndr family WEMBL PF05701.11 KND89370.1 - 0.037 12.7 4.3 0.05 12.3 4.3 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF4201 PF13870.6 KND89370.1 - 0.048 13.4 6.3 0.17 11.6 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) CENP-H PF05837.12 KND89370.1 - 0.058 13.8 4.0 1.6 9.2 0.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 KND89370.1 - 0.071 12.5 4.2 0.095 12.0 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 KND89370.1 - 0.075 13.1 9.0 1.2 9.3 0.9 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase MREG PF15812.5 KND89370.1 - 0.086 13.1 0.4 0.16 12.3 0.2 1.5 1 1 0 1 1 1 0 Melanoregulin Uso1_p115_C PF04871.13 KND89370.1 - 0.11 12.8 7.4 0.1 13.0 0.9 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin PF02996.17 KND89370.1 - 0.13 12.2 6.5 0.26 11.2 0.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit PHM7_cyt PF14703.6 KND89370.1 - 0.59 10.4 4.9 1.3 9.3 4.9 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DivIC PF04977.15 KND89370.1 - 0.76 9.6 16.0 2.6 7.9 1.7 3.1 2 2 1 3 3 3 0 Septum formation initiator GLE1 PF07817.13 KND89370.1 - 0.84 8.8 4.3 0.18 11.0 0.6 1.7 2 0 0 2 2 2 0 GLE1-like protein Spc24 PF08286.11 KND89370.1 - 1.9 8.7 10.2 2.4 8.4 2.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 KND89370.1 - 3.5 8.3 7.5 64 4.3 7.4 2.1 1 1 0 1 1 1 0 Initiation control protein YabA AAA PF00004.29 KND89371.1 - 2.6e-41 141.1 0.0 6.6e-41 139.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KND89371.1 - 1.8e-25 88.7 0.0 7.7e-25 86.7 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KND89371.1 - 4.8e-17 61.8 5.3 1.3e-16 60.3 5.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KND89371.1 - 9.1e-08 31.8 0.0 5.8e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KND89371.1 - 7.7e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KND89371.1 - 2.3e-05 23.8 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 KND89371.1 - 3.8e-05 24.1 0.8 0.0032 17.9 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 KND89371.1 - 5.4e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KND89371.1 - 9.4e-05 22.7 1.0 0.026 14.8 0.0 3.6 2 2 3 5 5 5 1 AAA domain AAA_14 PF13173.6 KND89371.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND89371.1 - 0.00012 22.4 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 KND89371.1 - 0.00018 21.5 0.0 0.00087 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KND89371.1 - 0.00025 20.3 0.1 0.0012 18.0 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 KND89371.1 - 0.00069 19.4 0.3 0.0082 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND89371.1 - 0.0012 19.4 0.1 0.0047 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain PrkA PF06798.12 KND89371.1 - 0.0014 18.3 0.4 0.0046 16.6 0.2 1.8 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain AAA_33 PF13671.6 KND89371.1 - 0.0038 17.4 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 KND89371.1 - 0.014 15.5 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KND89371.1 - 0.032 13.8 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KND89371.1 - 0.033 14.6 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND89371.1 - 0.036 13.6 0.2 0.18 11.3 0.0 2.3 3 1 0 3 3 3 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KND89371.1 - 0.041 13.3 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 KND89371.1 - 0.045 13.6 0.2 4 7.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TPR_12 PF13424.6 KND89371.1 - 0.066 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat PhoH PF02562.16 KND89371.1 - 0.08 12.4 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 KND89371.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin Cytidylate_kin PF02224.18 KND89371.1 - 0.74 9.5 2.7 0.82 9.4 0.1 2.5 3 0 0 3 3 3 0 Cytidylate kinase AAA PF00004.29 KND89373.1 - 5.4e-30 104.5 0.0 7.4e-13 49.1 0.0 3.9 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 KND89373.1 - 1.2e-15 57.4 4.1 4.5e-11 42.8 0.2 3.8 4 0 0 4 4 3 2 AAA lid domain AAA_22 PF13401.6 KND89373.1 - 4.1e-14 53.0 1.7 0.7 10.2 0.1 6.2 4 2 1 5 5 5 4 AAA domain RuvB_N PF05496.12 KND89373.1 - 9.3e-10 38.5 0.0 0.22 11.3 0.0 4.6 4 2 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND89373.1 - 1.1e-09 38.9 2.7 0.19 12.1 0.0 6.2 5 2 0 6 6 6 3 AAA ATPase domain AAA_5 PF07728.14 KND89373.1 - 3e-09 37.0 0.1 0.096 12.7 0.0 4.3 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KND89373.1 - 7e-08 32.4 0.0 0.037 13.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KND89373.1 - 2.3e-07 31.4 0.1 0.14 12.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 KND89373.1 - 6.4e-07 29.0 0.0 0.14 11.5 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KND89373.1 - 9.7e-07 29.0 1.8 0.46 10.6 0.1 3.8 3 0 0 3 3 3 3 AAA domain RNA_helicase PF00910.22 KND89373.1 - 1.8e-06 28.3 0.1 0.22 11.9 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 KND89373.1 - 2.5e-06 27.8 1.6 0.21 11.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 KND89373.1 - 1.8e-05 24.6 0.7 3.1 7.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KND89373.1 - 4.2e-05 24.1 0.1 0.19 12.3 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 KND89373.1 - 0.00013 22.3 2.0 1.1 9.5 0.0 4.1 3 1 1 4 4 4 1 AAA domain Sigma54_activat PF00158.26 KND89373.1 - 0.00023 20.9 1.7 1.3 8.7 0.0 5.3 5 1 0 5 5 5 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KND89373.1 - 0.00024 21.3 0.0 2.9 8.0 0.0 3.8 3 2 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.6 KND89373.1 - 0.00024 21.5 1.0 0.24 11.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain Torsin PF06309.11 KND89373.1 - 0.00053 20.1 0.0 4.6 7.4 0.0 3.6 3 0 0 3 3 3 0 Torsin TsaE PF02367.17 KND89373.1 - 0.00083 19.4 0.1 0.18 11.8 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KND89373.1 - 0.00089 19.1 0.1 0.71 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KND89373.1 - 0.0012 18.4 0.8 11 5.4 0.0 3.5 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KND89373.1 - 0.0013 18.5 0.0 7.2 6.3 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein TniB PF05621.11 KND89373.1 - 0.0025 17.3 0.1 28 4.0 0.0 4.7 4 1 0 4 4 4 0 Bacterial TniB protein Thymidylate_kin PF02223.17 KND89373.1 - 0.004 16.8 0.0 0.53 9.9 0.0 3.2 3 0 0 3 3 3 1 Thymidylate kinase Viral_helicase1 PF01443.18 KND89373.1 - 0.0064 16.3 0.0 2.9 7.6 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 KND89373.1 - 0.015 14.8 0.2 7.7 5.9 0.0 3.3 3 1 0 3 3 3 0 Chromatin associated protein KTI12 RsgA_GTPase PF03193.16 KND89373.1 - 0.021 14.7 0.0 8.8 6.2 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase Cytidylate_kin PF02224.18 KND89373.1 - 0.025 14.3 1.5 9.4 5.9 0.1 3.4 3 1 0 3 3 3 0 Cytidylate kinase SKI PF01202.22 KND89373.1 - 0.027 14.6 0.5 16 5.6 0.0 3.5 3 0 0 3 3 3 0 Shikimate kinase APS_kinase PF01583.20 KND89373.1 - 0.037 13.9 0.1 19 5.1 0.0 3.5 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_29 PF13555.6 KND89373.1 - 0.048 13.4 0.1 15 5.4 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain SRP54 PF00448.22 KND89373.1 - 0.064 12.9 4.1 5.1 6.7 0.0 3.9 5 0 0 5 5 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KND89373.1 - 0.066 13.1 0.8 15 5.4 0.1 3.4 3 0 0 3 3 3 0 NTPase VirE PF05272.11 KND89373.1 - 0.081 12.6 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Virulence-associated protein E Rad17 PF03215.15 KND89373.1 - 0.083 12.8 0.0 3.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KND89373.1 - 0.097 11.9 0.0 16 4.7 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_10 PF12846.7 KND89373.1 - 0.18 10.7 0.0 13 4.6 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.12 KND89373.1 - 0.48 10.3 2.2 64 3.4 0.0 4.2 4 1 0 4 4 4 0 NACHT domain Drc1-Sld2 PF11719.8 KND89374.1 - 2.8e-93 313.9 16.3 3.2e-93 313.7 16.3 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DNA_methylase PF00145.17 KND89375.1 - 3.7e-14 52.8 0.0 8.6e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase DASH_Spc34 PF08657.10 KND89376.1 - 4.3e-46 157.8 0.0 2.7e-23 83.1 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 zf-RING_2 PF13639.6 KND89377.1 - 3.6e-08 33.6 14.9 5.4e-08 33.0 14.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND89377.1 - 1.5e-06 28.0 10.0 2.1e-06 27.5 10.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND89377.1 - 6e-06 26.0 14.5 9.2e-06 25.4 14.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND89377.1 - 2.8e-05 23.9 15.0 4.1e-05 23.4 15.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND89377.1 - 0.0001 22.5 12.7 0.00022 21.4 12.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KND89377.1 - 0.22 11.3 9.4 0.41 10.4 9.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 KND89377.1 - 0.32 10.9 4.1 0.52 10.2 4.1 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KND89377.1 - 0.53 10.4 4.4 1.3 9.1 4.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KND89377.1 - 1.4 9.0 12.4 2.2 8.3 12.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 KND89377.1 - 4.1 7.4 6.9 6.4 6.7 6.9 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RrnaAD PF00398.20 KND89378.1 - 2e-07 30.3 0.0 3.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF2362 PF10154.9 KND89378.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) RrnaAD PF00398.20 KND89379.1 - 2e-07 30.3 0.0 3.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF2362 PF10154.9 KND89379.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Glyco_transf_90 PF05686.12 KND89380.1 - 4.5e-17 62.1 0.8 6.6e-12 45.0 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 90 CT_A_B PF02626.15 KND89381.1 - 3.9e-74 249.6 0.0 6.8e-74 248.8 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KND89381.1 - 4.7e-54 183.1 0.0 8.8e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KND89381.1 - 1.9e-33 115.9 0.0 4e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KND89381.1 - 2.6e-32 111.1 0.0 6.8e-32 109.8 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KND89381.1 - 5.2e-31 107.4 0.0 1.3e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KND89381.1 - 1.6e-10 40.7 3.6 4.8e-10 39.1 3.6 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KND89381.1 - 4.8e-06 26.3 2.6 0.047 13.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KND89381.1 - 0.00013 21.5 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 KND89381.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 KND89381.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Fungal_trans_2 PF11951.8 KND89382.1 - 9.3e-36 123.4 1.3 9.3e-36 123.4 1.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89382.1 - 5.2e-09 36.1 9.8 5.2e-09 36.1 9.8 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF676 PF05057.14 KND89384.1 - 1.5e-05 24.7 0.2 3e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND89384.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND89384.1 - 0.041 14.5 0.1 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 KND89384.1 - 0.067 13.0 0.1 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Sec7 PF01369.20 KND89385.1 - 1.4e-26 93.4 0.0 3.2e-26 92.1 0.0 1.5 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 KND89385.1 - 1.2e-18 67.6 0.0 2e-17 63.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain UNC-93 PF05978.16 KND89386.1 - 8.2e-09 35.4 5.1 8.2e-09 35.4 5.1 2.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KND89386.1 - 4.1e-08 32.5 37.0 4.1e-08 32.5 37.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Pho86 PF11124.8 KND89386.1 - 0.18 11.3 0.4 6.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 LamB_YcsF PF03746.16 KND89387.1 - 1.5e-72 244.2 0.3 1.7e-49 168.6 0.2 2.0 1 1 0 2 2 2 2 LamB/YcsF family DUF3798 PF12683.7 KND89387.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Amidase PF01425.21 KND89388.1 - 1.4e-103 347.3 0.0 1.6e-103 347.1 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF1524 PF07510.11 KND89389.1 - 7.4e-09 35.6 0.0 8.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Glyco_hydro_16 PF00722.21 KND89390.1 - 9.2e-29 100.1 2.2 1.4e-28 99.6 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 eIF3_N PF09440.10 KND89391.1 - 5.4e-45 153.1 2.2 9.9e-45 152.2 2.2 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KND89391.1 - 2.4e-11 44.1 0.0 6.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 KND89391.1 - 0.022 15.5 2.3 13 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC1 PF12859.7 KND89392.1 - 2.3e-41 141.4 0.2 9.3e-41 139.4 0.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KND89392.1 - 0.015 15.7 0.7 12 6.5 0.1 4.3 5 0 0 5 5 5 0 Proteasome/cyclosome repeat ARID PF01388.21 KND89393.1 - 5.2e-17 62.3 0.0 5.2e-17 62.3 0.0 2.8 2 1 1 3 3 3 1 ARID/BRIGHT DNA binding domain Img2 PF05046.14 KND89394.1 - 1e-14 54.5 0.1 1.3e-13 51.0 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) PRIMA1 PF16101.5 KND89394.1 - 0.076 13.0 0.9 0.1 12.6 0.9 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 GatB_N PF02934.15 KND89396.1 - 1.5e-99 332.9 0.0 1.9e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KND89396.1 - 2.2e-09 37.3 0.0 7.1e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 GatB domain Y2_Tnp PF04986.13 KND89396.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative transposase Clathrin PF00637.20 KND89397.1 - 1.5e-21 76.8 1.0 2.4e-20 72.9 0.5 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS RXT2_N PF08595.11 KND89397.1 - 0.0072 16.4 7.8 0.024 14.6 7.8 1.9 1 0 0 1 1 1 1 RXT2-like, N-terminal Vps39_1 PF10366.9 KND89397.1 - 0.016 15.5 1.0 0.13 12.5 0.3 2.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 SDA1 PF05285.12 KND89397.1 - 0.025 14.0 7.2 0.066 12.6 7.2 1.7 1 0 0 1 1 1 0 SDA1 NBP1 PF08537.10 KND89397.1 - 0.039 13.4 0.1 0.077 12.4 0.1 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 WD40 PF00400.32 KND89397.1 - 0.2 12.6 1.7 14 6.8 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat TPR_7 PF13176.6 KND89397.1 - 0.34 11.1 3.2 1.6 8.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 KND89397.1 - 0.35 10.9 0.9 0.99 9.4 0.9 1.8 1 1 0 1 1 1 0 zinc-RING finger domain BUD22 PF09073.10 KND89397.1 - 0.38 10.0 12.6 0.078 12.3 9.0 1.6 2 0 0 2 2 2 0 BUD22 zf-RING_2 PF13639.6 KND89397.1 - 0.69 10.3 2.0 2.5 8.5 0.4 2.3 2 0 0 2 2 2 0 Ring finger domain DNA_pol_phi PF04931.13 KND89397.1 - 1.1 7.3 16.6 1.9 6.5 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 KND89397.1 - 1.9 9.0 6.2 6 7.4 6.2 1.8 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPP4R2 PF09184.11 KND89397.1 - 3.6 7.1 15.3 8.8 5.8 15.3 1.6 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 KND89397.1 - 4.5 6.9 20.4 0.36 10.5 14.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF824 PF05688.11 KND89398.1 - 0.82 9.5 4.0 0.42 10.5 1.2 1.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) U3_assoc_6 PF08640.11 KND89399.1 - 2.3e-27 94.9 0.8 4.7e-25 87.5 0.3 3.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KND89399.1 - 0.00024 21.7 0.3 0.34 11.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KND89399.1 - 0.00077 18.7 1.7 0.0017 17.6 1.7 1.6 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference DUF4548 PF15081.6 KND89399.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) Pkinase PF00069.25 KND89401.1 - 1.3e-20 73.9 0.0 3.8e-20 72.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KND89401.1 - 1.2e-07 30.8 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KND89401.1 - 1.3e-05 24.6 0.0 0.00085 18.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3435 PF11917.8 KND89402.1 - 6.9e-17 61.5 0.0 2e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) zf-C2H2_jaz PF12171.8 KND89402.1 - 0.014 15.7 0.8 0.014 15.7 0.8 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND89402.1 - 0.34 11.3 2.8 1.3 9.5 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.25 KND89403.1 - 5.8e-13 48.8 0.0 9.3e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89403.1 - 2.7e-06 26.9 0.0 5.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND89403.1 - 7.7e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KND89403.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND89403.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KND89403.1 - 0.0086 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KND89403.1 - 0.014 14.7 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KND89403.1 - 0.098 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_12 PF13424.6 KND89404.1 - 1.4e-11 44.5 0.3 6.8e-05 23.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND89404.1 - 3.7e-10 39.4 0.5 0.00076 19.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat FRQ PF09421.10 KND89405.1 - 0 1468.1 36.8 0 1467.7 36.8 1.0 1 0 0 1 1 1 1 Frequency clock protein Prenylcys_lyase PF07156.14 KND89405.1 - 1e-90 304.5 0.0 1.5e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KND89405.1 - 3.2e-10 40.1 0.0 9.1e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KND89405.1 - 3.2e-07 30.0 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DUF5558 PF17713.1 KND89405.1 - 0.0051 17.2 0.9 0.022 15.1 0.9 2.2 1 0 0 1 1 1 1 Family of unknown function (DUF5558) DAO PF01266.24 KND89405.1 - 0.095 12.3 0.2 0.46 10.0 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAM199X PF15814.5 KND89405.1 - 2.6 7.0 8.6 0.33 10.0 1.6 2.3 2 0 0 2 2 2 0 Protein family FAM199X iPGM_N PF06415.13 KND89406.1 - 3.5e-76 255.4 0.0 4.9e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KND89406.1 - 1.1e-67 228.0 0.0 1.3e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KND89406.1 - 1.4e-07 31.2 0.0 3.3e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KND89406.1 - 0.00066 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase AP_endonuc_2 PF01261.24 KND89406.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Med9 PF07544.13 KND89407.1 - 2e-18 66.2 0.1 4.2e-18 65.2 0.1 1.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Spc29 PF17082.5 KND89407.1 - 0.037 13.9 0.0 0.048 13.5 0.0 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 Med21 PF11221.8 KND89407.1 - 0.038 14.2 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DivIC PF04977.15 KND89407.1 - 0.056 13.2 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator TBCC PF07986.12 KND89408.1 - 1.1e-29 102.6 0.1 1.7e-29 102.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KND89408.1 - 1.7e-10 41.4 0.0 3.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain F_actin_bind PF08919.10 KND89408.1 - 0.0011 19.0 0.0 0.12 12.5 0.0 2.5 1 1 1 2 2 2 1 F-actin binding RTX PF02382.15 KND89408.1 - 0.061 13.0 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein NPV_P10 PF05531.12 KND89408.1 - 0.31 11.5 2.6 1.4 9.5 2.6 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Gpi1 PF05024.15 KND89409.1 - 1.8e-78 262.9 6.8 2.9e-78 262.3 6.8 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.12 KND89409.1 - 1.3e-25 89.4 4.5 2.5e-25 88.5 4.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.21 KND89409.1 - 0.0058 16.0 0.3 0.013 14.8 0.3 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) COX17 PF05051.13 KND89409.1 - 0.016 15.6 1.3 0.035 14.5 1.3 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KND89409.1 - 0.025 14.6 3.7 0.11 12.5 0.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like INTS5_N PF14837.6 KND89409.1 - 0.033 13.8 0.1 4.2 6.9 0.0 2.7 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus DUF92 PF01940.16 KND89409.1 - 0.078 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF92 PAF-AH_p_II PF03403.13 KND89412.1 - 3.1e-14 52.3 0.1 2.9e-08 32.6 0.1 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KND89412.1 - 0.00044 19.3 0.0 0.0092 14.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KND89412.1 - 0.0021 17.4 0.1 0.098 11.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KND89412.1 - 0.0034 17.1 0.1 0.77 9.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND89412.1 - 0.014 15.1 0.2 0.82 9.3 0.1 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold Glycos_transf_2 PF00535.26 KND89413.1 - 7.5e-34 117.0 0.0 9e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KND89413.1 - 1.8e-12 47.7 0.0 2.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KND89413.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 KND89413.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 adh_short_C2 PF13561.6 KND89414.1 - 1.1e-47 162.6 3.2 1.3e-41 142.7 1.4 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND89414.1 - 1.2e-46 158.7 1.4 1.6e-46 158.3 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND89414.1 - 1e-14 54.9 0.4 1.4e-14 54.4 0.4 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KND89414.1 - 0.015 15.2 1.5 0.027 14.3 1.4 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KND89414.1 - 0.047 13.8 0.3 0.087 12.9 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KND89414.1 - 0.13 11.8 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nop52 PF05997.12 KND89415.1 - 9.6e-47 159.6 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TetR_C_34 PF17929.1 KND89415.1 - 0.16 12.1 7.4 0.081 13.0 1.0 2.5 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF2156 PF09924.9 KND89416.1 - 0.019 14.0 0.5 0.031 13.3 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) AATase PF07247.12 KND89417.1 - 3.1e-17 62.3 0.0 3.6e-13 48.9 0.0 2.6 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 KND89417.1 - 0.00017 20.4 0.3 0.0035 16.1 0.3 2.0 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 KND89417.1 - 0.03 14.1 5.2 0.036 13.8 3.9 1.7 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF2267 PF10025.9 KND89417.1 - 0.046 14.0 1.2 0.12 12.7 1.2 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) RSN1_7TM PF02714.15 KND89418.1 - 6.4e-79 265.1 18.5 1.1e-78 264.3 18.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KND89418.1 - 7.1e-37 127.3 0.0 9.4e-36 123.7 0.0 2.2 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KND89418.1 - 3.1e-14 53.0 2.3 3.1e-14 53.0 2.3 1.9 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport TFIIB PF00382.19 KND89419.1 - 4.9e-30 103.4 1.0 2.5e-19 69.1 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KND89419.1 - 2.8e-24 85.4 1.1 2.8e-24 85.4 1.1 3.3 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KND89419.1 - 6.9e-05 22.6 0.7 0.0062 16.3 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain adh_short PF00106.25 KND89420.1 - 3.2e-27 95.3 0.0 4.4e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND89420.1 - 2.3e-17 63.3 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND89420.1 - 8e-05 22.6 1.1 0.0036 17.2 0.2 2.3 2 0 0 2 2 2 2 KR domain MFS_1 PF07690.16 KND89421.1 - 5.9e-36 124.1 27.5 1e-35 123.3 27.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89421.1 - 9.3e-07 28.1 14.0 1.4e-06 27.4 14.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Protocadherin PF08374.11 KND89421.1 - 0.24 11.4 0.0 0.47 10.4 0.0 1.5 1 0 0 1 1 1 0 Protocadherin DUF3147 PF11345.8 KND89421.1 - 1.2 9.5 9.5 0.068 13.5 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Zn_clus PF00172.18 KND89422.1 - 1.9e-10 40.7 8.8 3.9e-10 39.7 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND89422.1 - 0.025 13.4 0.1 0.037 12.8 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain PP2C PF00481.21 KND89423.1 - 1.5e-30 106.7 0.0 2.6e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SO_alpha_A3 PF17806.1 KND89423.1 - 0.29 11.5 1.8 19 5.7 0.1 2.6 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain 2-Hacid_dh_C PF02826.19 KND89425.1 - 5.5e-55 185.5 0.0 7.5e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND89425.1 - 9e-20 70.7 0.0 1.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND89425.1 - 1.1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 KND89425.1 - 0.074 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DUF1338 PF07063.13 KND89426.1 - 4.8e-103 344.8 0.0 5.5e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) AA_permease PF00324.21 KND89427.1 - 6.7e-132 440.5 35.2 8.6e-132 440.1 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND89427.1 - 4.5e-30 104.8 35.6 5.8e-30 104.5 35.4 1.3 1 1 0 1 1 1 1 Amino acid permease EI24 PF07264.11 KND89428.1 - 0.003 17.8 1.7 0.085 13.1 1.7 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Autophagy_act_C PF03987.15 KND89429.1 - 1.6e-13 51.0 0.3 4.4e-13 49.6 0.3 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.20 KND89430.1 - 7.4e-169 562.5 0.0 8.7e-169 562.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ycf66_N PF07444.11 KND89430.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Ycf66 protein N-terminus AA_permease PF00324.21 KND89431.1 - 1.5e-143 478.9 37.4 1.7e-143 478.7 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND89431.1 - 1e-38 133.3 37.7 1.2e-38 133.0 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease SnoaL PF07366.12 KND89432.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF3549 PF12069.8 KND89432.1 - 0.79 8.7 3.6 0.94 8.4 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3549) PrpF PF04303.13 KND89433.1 - 5.7e-93 311.8 7.3 6e-87 292.0 3.0 2.0 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.18 KND89434.1 - 3.1e-24 85.4 0.5 4.6e-24 84.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89434.1 - 6.6e-08 32.6 7.8 1.2e-07 31.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KND89435.1 - 0.00073 19.4 2.3 0.00088 19.1 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND89435.1 - 0.0063 16.4 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 KND89436.1 - 6.7e-52 173.4 6.9 6.6e-20 70.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 KND89437.1 - 3.9e-29 101.7 25.1 3.9e-29 101.7 25.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND89437.1 - 3.9e-07 29.7 3.3 3.9e-07 29.7 3.3 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 KND89437.1 - 0.057 13.2 2.4 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_3 PF16080.5 KND89437.1 - 6.7 6.6 7.9 40 4.1 0.0 3.9 4 0 0 4 4 4 0 Bacteriophage holin family HP1 Ribonuc_L-PSP PF01042.21 KND89438.1 - 1.2e-41 141.6 0.0 1.7e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP WD40 PF00400.32 KND89439.1 - 3.6e-18 65.6 11.3 0.0015 19.3 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND89439.1 - 3.8e-08 33.5 0.0 0.031 14.6 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 KND89440.1 - 2.2e-08 33.8 0.0 6.3e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND89440.1 - 3.2e-08 33.2 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND89440.1 - 0.041 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_9 PF18444.1 KND89440.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Pkinase PF00069.25 KND89441.1 - 3.4e-51 174.1 0.1 4.6e-51 173.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89441.1 - 2.7e-26 92.4 0.1 4e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND89441.1 - 0.076 12.4 0.9 1.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND89441.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KND89441.1 - 0.2 10.6 0.1 0.3 10.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 KND89442.1 - 6.1e-54 183.1 0.0 7.8e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89442.1 - 6.8e-31 107.5 0.0 8.8e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND89442.1 - 0.00019 20.9 0.0 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KND89442.1 - 0.00033 20.1 0.0 0.0005 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND89442.1 - 0.0012 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KND89442.1 - 0.002 17.8 0.0 0.077 12.6 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KND89442.1 - 0.0036 16.2 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase UL11 PF11094.8 KND89442.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Membrane-associated tegument protein Haspin_kinase PF12330.8 KND89442.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KND89442.1 - 0.054 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Auxin_inducible PF02519.14 KND89443.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Auxin responsive protein ADP_ribosyl_GH PF03747.14 KND89444.1 - 2.9e-60 204.5 0.3 3.9e-60 204.1 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 KND89444.1 - 0.44 10.5 4.2 0.63 10.0 0.3 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KND89444.1 - 7.6 6.6 9.6 2.1 8.4 0.4 2.8 3 0 0 3 3 3 0 Glycine zipper Ferric_reduct PF01794.19 KND89445.1 - 1.7e-24 86.3 17.0 4.4e-24 85.0 17.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KND89445.1 - 3.8e-07 30.2 0.2 2.1e-06 27.8 0.2 2.2 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 KND89445.1 - 2.1e-06 27.9 0.1 0.032 14.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 KND89445.1 - 1.7e-05 25.5 0.0 3.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ANAPC4_WD40 PF12894.7 KND89446.1 - 0.002 18.4 0.1 0.03 14.6 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain YL1 PF05764.13 KND89446.1 - 0.026 14.7 6.6 0.041 14.0 6.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2722 PF10846.8 KND89446.1 - 0.6 9.0 7.0 0.8 8.6 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BUD22 PF09073.10 KND89446.1 - 3.5 6.9 11.3 6.2 6.0 11.3 1.3 1 0 0 1 1 1 0 BUD22 HlyIII PF03006.20 KND89447.1 - 1.7e-63 214.3 13.5 2e-63 214.1 13.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 KND89447.1 - 0.21 11.7 4.6 0.065 13.3 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) TMA7 PF09072.10 KND89448.1 - 9.2e-17 61.6 21.4 2.3e-08 34.7 6.3 2.4 3 0 0 3 3 3 2 Translation machinery associated TMA7 ANAPC3 PF12895.7 KND89449.1 - 0.0015 18.8 0.1 0.0045 17.2 0.1 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KND89449.1 - 0.056 13.7 4.3 7.8 6.9 0.7 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND89449.1 - 0.13 12.8 1.5 3.7 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND89449.1 - 0.18 12.5 0.6 93 4.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND89449.1 - 0.23 12.2 0.3 0.23 12.2 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat pRN1_helical PF13010.6 KND89450.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Primase helical domain 2-oxoacid_dh PF00198.23 KND89452.1 - 9.1e-75 251.1 0.0 1.2e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KND89452.1 - 3e-17 62.2 0.1 5.6e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KND89452.1 - 1.5e-12 47.6 0.5 5.1e-12 45.9 0.5 2.0 1 0 0 1 1 1 1 e3 binding domain SKI PF01202.22 KND89453.1 - 2.5e-10 40.7 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 KND89453.1 - 2.4e-09 37.5 0.0 3.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND89453.1 - 2.3e-08 34.7 0.0 2.1e-07 31.5 0.0 2.4 1 1 1 2 2 1 1 AAA domain AAA_17 PF13207.6 KND89453.1 - 1.7e-06 28.5 0.0 3.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 KND89453.1 - 5.4e-06 26.3 0.1 1.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 KND89453.1 - 2e-05 25.0 0.0 5.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND89453.1 - 3e-05 24.0 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KND89453.1 - 0.00015 22.2 0.0 0.00019 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND89453.1 - 0.00035 20.8 0.0 0.00082 19.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain dNK PF01712.19 KND89453.1 - 0.00042 20.2 0.0 0.064 13.1 0.0 2.3 2 1 0 2 2 2 1 Deoxynucleoside kinase PRK PF00485.18 KND89453.1 - 0.0012 18.7 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 KND89453.1 - 0.002 17.8 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Dephospho-CoA kinase AAA_5 PF07728.14 KND89453.1 - 0.0025 17.8 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 KND89453.1 - 0.0035 17.3 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 KND89453.1 - 0.0039 17.6 0.0 0.0074 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.6 KND89453.1 - 0.0042 17.2 0.0 0.18 11.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.6 KND89453.1 - 0.0047 17.2 0.0 0.0075 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KND89453.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 KND89453.1 - 0.0083 15.8 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.15 KND89453.1 - 0.01 15.7 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 KND89453.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 KND89453.1 - 0.022 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KND89453.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KND89453.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 KND89453.1 - 0.033 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 KND89453.1 - 0.034 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KND89453.1 - 0.04 13.5 0.1 0.072 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KND89453.1 - 0.045 14.1 0.0 0.16 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KND89453.1 - 0.052 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.27 KND89453.1 - 0.067 13.7 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.6 KND89453.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 KND89453.1 - 0.074 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KND89453.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 KND89453.1 - 0.1 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 KND89453.1 - 0.14 11.7 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 zf-H2C2_2 PF13465.6 KND89454.1 - 2e-22 78.5 30.8 4.6e-07 30.0 0.7 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 KND89454.1 - 1.2e-18 66.4 46.3 0.00031 21.0 3.1 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND89454.1 - 1.3e-12 47.4 41.8 0.003 18.3 2.2 8.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND89454.1 - 1.4e-07 31.3 26.1 0.00021 21.2 1.6 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND89454.1 - 0.00012 22.3 22.8 0.055 13.8 0.8 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KND89454.1 - 0.077 13.0 21.0 3.8 7.6 0.2 4.7 1 1 3 4 4 4 0 BED zinc finger ARS2 PF04959.13 KND89454.1 - 0.89 9.9 6.8 7.3 6.9 1.2 3.0 3 0 0 3 3 3 0 Arsenite-resistance protein 2 zf-C2H2_11 PF16622.5 KND89454.1 - 3.7 7.4 21.0 0.95 9.3 0.1 5.2 5 0 0 5 5 5 0 zinc-finger C2H2-type V-SNARE_C PF12352.8 KND89455.1 - 2.2e-13 50.3 0.5 2.2e-13 50.3 0.5 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus IL28A PF15177.6 KND89455.1 - 0.04 13.7 1.1 0.096 12.5 0.1 2.0 2 1 0 2 2 2 0 Interleukin-28A FTCD_C PF04961.12 KND89455.1 - 0.045 13.5 1.2 0.27 11.0 0.3 2.0 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase ECH_2 PF16113.5 KND89455.1 - 0.084 12.4 0.2 0.13 11.8 0.2 1.3 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Vps54_N PF10475.9 KND89455.1 - 0.13 11.5 3.3 8.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 KND89455.1 - 0.4 9.5 5.5 0.36 9.7 4.0 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein AIM3 PF17096.5 KND89456.1 - 0.16 12.9 4.9 0.29 12.1 4.9 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Ribosomal_L29 PF00831.23 KND89457.1 - 2.8e-17 62.4 1.2 2.8e-17 62.4 1.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein HCNGP PF07818.13 KND89458.1 - 3e-29 101.5 0.0 5.9e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein DEAD PF00270.29 KND89459.1 - 3.2e-49 167.1 0.0 5.6e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND89459.1 - 4.1e-26 91.5 0.0 1.8e-25 89.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Peptidase_M49 PF03571.15 KND89460.1 - 3.9e-245 814.4 0.0 4.7e-245 814.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Ribosomal_L6e PF01159.19 KND89461.1 - 4.7e-39 133.4 0.3 4.7e-39 133.4 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e BTB PF00651.31 KND89462.1 - 0.016 15.4 0.1 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain zf-C2H2_4 PF13894.6 KND89463.1 - 0.01 16.6 1.0 0.042 14.7 1.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Ppx-GppA PF02541.16 KND89464.1 - 8e-25 87.8 0.0 1.7e-24 86.7 0.0 1.4 1 1 0 1 1 1 1 Ppx/GppA phosphatase family F-box-like PF12937.7 KND89465.1 - 0.0019 18.1 1.0 0.0068 16.3 1.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KND89465.1 - 0.0027 18.1 6.7 0.49 10.9 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 KND89465.1 - 0.033 14.1 1.0 0.033 14.1 1.0 2.8 2 1 0 2 2 2 0 F-box domain F-box_4 PF15966.5 KND89465.1 - 0.094 12.6 1.0 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 F-box IU_nuc_hydro PF01156.19 KND89466.1 - 1.2e-81 274.6 0.1 1.4e-81 274.4 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KND89467.1 - 8.3e-07 28.8 10.0 8.3e-07 28.8 10.0 2.1 2 1 0 2 2 2 1 RED-like protein N-terminal region DUF2924 PF11149.8 KND89467.1 - 0.084 13.3 0.4 0.084 13.3 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2924) Lsm_interact PF05391.11 KND89467.1 - 1.9 8.1 7.4 0.42 10.2 1.6 2.7 2 0 0 2 2 2 0 Lsm interaction motif MFS_2 PF13347.6 KND89468.1 - 5.5e-09 35.1 9.7 2.1e-08 33.2 9.7 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 KND89468.1 - 0.0081 15.1 4.1 0.0098 14.8 1.8 2.3 2 1 0 2 2 2 1 MFS_1 like family Pkr1 PF08636.10 KND89469.1 - 1.6e-31 108.2 4.4 2e-31 107.9 4.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 RhoGEF PF00621.20 KND89470.1 - 7.7e-31 107.7 0.1 1.4e-30 106.9 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 KND89470.1 - 2.1e-08 34.1 0.1 2.1e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 BAR domain LPD13 PF18825.1 KND89470.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 MBOAT_2 PF13813.6 KND89471.1 - 9.8e-15 54.6 6.2 3e-14 53.0 6.2 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Zn_clus PF00172.18 KND89472.1 - 9.4e-06 25.7 7.7 3.2e-05 23.9 7.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 KND89473.1 - 4.9 7.0 7.4 6.3 6.6 7.4 1.1 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 KND89474.1 - 7e-62 205.4 1.3 1.5e-20 72.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND89474.1 - 0.13 11.4 0.1 0.54 9.4 0.0 2.0 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 KND89475.1 - 3.9e-59 196.6 0.1 8.9e-19 67.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AICARFT_IMPCHas PF01808.18 KND89476.1 - 3.6e-91 305.7 0.0 4.7e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KND89476.1 - 1.3e-23 83.0 0.0 2.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Questin_oxidase PF14027.6 KND89477.1 - 2.7e-86 290.2 1.0 4.2e-86 289.6 1.0 1.3 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 KND89477.1 - 2.4e-25 89.6 0.0 4.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 KND89477.1 - 0.0013 18.8 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KND89477.1 - 0.004 16.9 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND89477.1 - 0.0052 17.2 3.6 0.0084 16.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 KND89477.1 - 0.0089 16.4 0.0 0.033 14.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND89477.1 - 0.09 13.0 0.1 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KND89477.1 - 0.11 12.3 0.1 0.33 10.9 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KND89477.1 - 0.14 12.3 0.0 0.51 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain SCRG1 PF15224.6 KND89477.1 - 0.24 11.6 0.4 0.57 10.3 0.0 1.8 2 0 0 2 2 2 0 Scrapie-responsive protein 1 TAFII55_N PF04658.13 KND89479.1 - 7e-51 172.1 0.8 1.5e-50 171.0 0.0 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region DUF3074 PF11274.8 KND89480.1 - 1.5e-42 145.6 0.7 1.5e-42 145.6 0.7 2.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3074) p450 PF00067.22 KND89481.1 - 8e-72 242.5 0.0 1e-71 242.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Stk19 PF10494.9 KND89482.1 - 1.9e-64 217.7 0.0 2.4e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Herpes_IE68 PF02479.16 KND89483.1 - 0.017 14.7 0.2 0.017 14.7 0.2 1.9 2 2 0 2 2 2 0 Herpesvirus immediate early protein Kinesin PF00225.23 KND89485.1 - 4.1e-94 315.2 0.0 7.6e-94 314.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND89485.1 - 2.7e-21 76.1 0.0 7.2e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding RRM_1 PF00076.22 KND89487.1 - 1.1e-36 124.5 0.7 8.4e-18 64.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND89487.1 - 0.00034 20.7 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif SET_assoc PF11767.8 KND89487.1 - 0.0049 16.5 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Telomerase_RBD PF12009.8 KND89489.1 - 2e-51 173.6 0.0 3.6e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KND89489.1 - 5.7e-15 55.4 0.0 3e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PNP_UDP_1 PF01048.20 KND89490.1 - 9e-12 44.7 0.0 4.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily OrfB_Zn_ribbon PF07282.11 KND89490.1 - 0.0013 18.7 0.2 0.0031 17.4 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C2H2_3 PF13878.6 KND89490.1 - 0.13 12.1 1.7 2.9 7.8 0.1 2.8 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO GAGA PF09237.11 KND89490.1 - 0.79 9.6 3.1 0.35 10.7 0.2 1.9 2 0 0 2 2 2 0 GAGA factor Annexin PF00191.20 KND89492.1 - 1.2e-58 195.0 3.5 5.3e-15 55.2 0.0 4.7 4 2 0 4 4 4 4 Annexin DUF3574 PF12098.8 KND89492.1 - 0.073 12.9 0.1 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) Lipase_GDSL_2 PF13472.6 KND89493.1 - 4.3e-16 59.8 0.1 5.5e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND89493.1 - 0.00028 20.9 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HTH_AsnC-type PF13404.6 KND89493.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PCI PF01399.27 KND89495.1 - 3.7e-12 46.7 0.0 2.1e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 KND89495.1 - 0.00018 21.3 0.5 0.00018 21.3 0.5 2.1 2 1 1 3 3 3 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 KND89495.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 ComR tetratricopeptide zf-C2H2 PF00096.26 KND89496.1 - 0.0025 18.2 4.1 0.28 11.7 0.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND89496.1 - 0.014 16.1 2.0 6.7 7.8 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 KND89496.1 - 0.081 12.4 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KND89496.1 - 0.1 12.7 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 KND89496.1 - 0.11 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double domain Cullin PF00888.22 KND89497.1 - 6.9e-24 84.4 0.0 1.1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KND89497.1 - 1.4e-21 76.8 0.0 3.7e-21 75.4 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 PKcGMP_CC PF16808.5 KND89498.1 - 0.0011 18.7 1.4 0.054 13.4 0.1 2.8 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 KND89498.1 - 0.0046 17.0 5.7 0.12 12.5 1.2 3.8 2 0 0 2 2 2 1 bZIP transcription factor Csm1_N PF18504.1 KND89498.1 - 0.021 15.2 9.5 0.26 11.6 1.0 4.3 2 1 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 KND89498.1 - 0.028 13.3 9.9 0.099 11.5 9.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 KND89498.1 - 0.056 13.6 10.0 1.7 8.8 0.1 3.8 2 0 0 2 2 2 0 Up-regulated During Septation DivIC PF04977.15 KND89498.1 - 5.3 6.9 10.9 0.92 9.3 0.8 3.6 2 1 1 3 3 3 0 Septum formation initiator PHB_acc PF05233.13 KND89499.1 - 0.013 15.5 1.1 0.039 14.0 0.6 2.1 2 0 0 2 2 2 0 PHB accumulation regulatory domain FAINT PF04385.15 KND89501.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, DUF529 Fungal_trans_2 PF11951.8 KND89502.1 - 9.4e-13 47.7 0.3 1.5e-12 47.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89502.1 - 4e-06 26.8 15.8 7.6e-06 26.0 15.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 KND89503.1 - 8.9e-19 68.2 0.0 1.6e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND89503.1 - 7.4e-05 22.8 0.0 0.00081 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND89503.1 - 0.0005 20.3 0.1 0.0047 17.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KND89503.1 - 0.00076 19.9 0.1 0.0024 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 KND89503.1 - 0.0011 18.7 0.0 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_18 PF13238.6 KND89503.1 - 0.025 15.1 0.0 0.069 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KND89503.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 KND89503.1 - 0.033 13.2 0.0 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein SR-25 PF10500.9 KND89503.1 - 0.048 13.3 1.7 0.096 12.3 1.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA_2 PF07724.14 KND89503.1 - 0.055 13.6 0.0 0.16 12.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KND89503.1 - 0.084 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KND89503.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 KND89503.1 - 0.095 12.9 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND89503.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KND89503.1 - 0.14 11.4 0.0 0.57 9.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Aconitase_B_N PF11791.8 KND89503.1 - 0.16 12.1 0.2 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 Aconitate B N-terminal domain BTB PF00651.31 KND89504.1 - 3.5e-14 53.0 0.1 7.1e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain HypA PF01155.19 KND89504.1 - 0.031 14.3 0.1 0.075 13.1 0.1 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Beta-lactamase PF00144.24 KND89505.1 - 8.2e-30 104.2 2.5 1.4e-29 103.4 2.5 1.3 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KND89506.1 - 8.9e-08 31.3 0.0 4.8e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89506.1 - 1.3e-06 28.4 8.0 3.4e-06 27.1 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 KND89507.1 - 3.5e-87 287.1 22.6 1.9e-14 54.0 0.8 7.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND89507.1 - 5.6e-47 157.5 15.9 9.8e-08 32.4 0.1 11.4 2 2 10 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 KND89507.1 - 5.2e-41 137.3 23.6 0.0021 18.5 0.0 13.4 12 1 1 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 KND89507.1 - 2.7e-39 128.7 8.7 0.05 14.2 0.1 13.1 12 1 1 13 13 12 9 Ankyrin repeat Ank_5 PF13857.6 KND89507.1 - 5e-23 80.9 15.7 0.0026 18.0 0.0 8.3 4 2 5 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.12 KND89507.1 - 4.4e-15 56.0 0.1 7.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND89507.1 - 6.8e-08 33.1 0.0 2.4e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KND89507.1 - 1.1e-05 25.5 0.0 0.0015 18.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KND89507.1 - 1.1e-05 25.8 0.0 3.6e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND89507.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KND89507.1 - 0.0029 17.6 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KND89507.1 - 0.007 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain RTC4 PF14474.6 KND89507.1 - 0.017 15.3 4.5 2.2 8.4 0.0 4.0 3 1 0 3 3 3 0 RTC4-like domain RNA_helicase PF00910.22 KND89507.1 - 0.026 14.9 0.0 0.07 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RelB_N PF18506.1 KND89507.1 - 0.056 13.2 0.0 61 3.5 0.0 5.7 9 0 0 9 9 9 0 RelB Antitoxin alpha helical domain Ank_4 PF13637.6 KND89508.1 - 0.05 14.2 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RabGAP-TBC PF00566.18 KND89509.1 - 1e-33 116.8 0.0 4.1e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 Rab-GTPase-TBC domain UQ_con PF00179.26 KND89510.1 - 4.6e-35 120.3 0.1 5.2e-35 120.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND89510.1 - 7.7e-06 25.6 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B TMF_TATA_bd PF12325.8 KND89512.1 - 0.021 15.0 1.0 0.021 15.0 1.0 8.6 5 3 2 8 8 8 0 TATA element modulatory factor 1 TATA binding Med16 PF11635.8 KND89513.1 - 6.6e-76 255.8 0.0 8.2e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 FAD-oxidase_C PF02913.19 KND89514.1 - 2.9e-59 200.7 0.1 4e-59 200.3 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KND89514.1 - 5.4e-36 123.4 0.0 1.1e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.28 KND89514.1 - 0.00084 18.5 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region DNA_pol_B_palm PF14792.6 KND89515.1 - 1.2e-34 119.0 0.0 2.3e-34 118.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KND89515.1 - 8e-25 86.8 0.7 5.6e-24 84.1 0.4 2.5 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KND89515.1 - 4.3e-21 74.5 0.2 1.4e-20 72.8 0.2 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KND89515.1 - 3.4e-16 59.4 3.0 3.9e-16 59.2 0.2 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 KND89515.1 - 0.039 14.3 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Cdd1 PF11731.8 KND89515.1 - 0.045 14.0 0.0 7 7.0 0.0 3.3 2 1 1 3 3 3 0 Pathogenicity locus HHH_5 PF14520.6 KND89515.1 - 0.048 14.3 0.0 0.71 10.5 0.0 2.3 1 1 2 3 3 3 0 Helix-hairpin-helix domain BRCT_2 PF16589.5 KND89515.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain HHH_2 PF12826.7 KND89515.1 - 0.12 12.5 0.0 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif RCDG1 PF15725.5 KND89515.1 - 1.3 9.5 4.4 35 4.9 0.1 2.8 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Brix PF04427.18 KND89516.1 - 2.1e-49 168.3 0.0 2.8e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain CSRNP_N PF16019.5 KND89516.1 - 3.7 7.4 8.2 12 5.8 3.3 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF2407_C PF13373.6 KND89516.1 - 7.4 6.7 6.1 3.5 7.8 3.4 1.8 2 0 0 2 2 2 0 DUF2407 C-terminal domain ABC_tran PF00005.27 KND89517.1 - 2.8e-51 173.7 0.0 3.5e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND89517.1 - 8.6e-28 97.8 11.2 8.6e-28 97.8 11.2 3.1 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KND89517.1 - 2.2e-09 37.1 2.0 0.21 11.0 0.0 4.3 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND89517.1 - 2.6e-08 33.5 0.5 0.0055 16.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND89517.1 - 5.5e-08 32.9 0.1 0.0031 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KND89517.1 - 1.7e-06 28.3 0.5 0.14 12.4 0.1 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KND89517.1 - 1.9e-06 27.9 0.2 0.02 15.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 KND89517.1 - 2.8e-06 27.8 0.2 2.9 8.3 0.1 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KND89517.1 - 3e-06 27.9 0.1 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KND89517.1 - 4.6e-06 26.3 0.1 0.045 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_21 PF13304.6 KND89517.1 - 5.9e-06 26.3 0.9 0.07 12.9 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KND89517.1 - 4.8e-05 23.8 0.1 0.7 10.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 KND89517.1 - 0.00016 22.3 0.0 0.49 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KND89517.1 - 0.00016 21.8 0.3 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family IstB_IS21 PF01695.17 KND89517.1 - 0.00046 20.0 0.1 0.26 11.0 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 KND89517.1 - 0.00052 19.6 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KND89517.1 - 0.00053 19.8 0.1 0.52 10.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 KND89517.1 - 0.00053 20.0 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea T2SSE PF00437.20 KND89517.1 - 0.00063 18.9 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 KND89517.1 - 0.0012 18.9 4.7 0.073 13.2 0.1 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain Viral_helicase1 PF01443.18 KND89517.1 - 0.0014 18.4 0.5 3.1 7.5 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KND89517.1 - 0.0024 18.0 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KND89517.1 - 0.0036 17.3 0.7 0.44 10.4 0.0 2.8 3 0 0 3 3 2 1 NTPase RNA_helicase PF00910.22 KND89517.1 - 0.004 17.5 0.1 4.8 7.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase TsaE PF02367.17 KND89517.1 - 0.0044 17.0 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 KND89517.1 - 0.0044 16.4 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 KND89517.1 - 0.0064 16.2 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 KND89517.1 - 0.0073 15.9 0.8 0.69 9.5 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KND89517.1 - 0.011 15.5 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 KND89517.1 - 0.013 14.6 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KND89517.1 - 0.026 13.8 0.2 7.1 5.8 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin NB-ARC PF00931.22 KND89517.1 - 0.028 13.6 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 KND89517.1 - 0.031 14.0 1.4 4.2 7.0 0.0 3.2 3 1 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.15 KND89517.1 - 0.036 12.9 0.1 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.17 KND89517.1 - 0.057 13.2 0.2 6.1 6.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 KND89517.1 - 0.099 11.5 0.4 12 4.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 KND89517.1 - 0.12 12.3 0.3 34 4.4 0.1 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KND89517.1 - 0.15 11.3 0.2 9.8 5.4 0.1 2.3 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.6 KND89517.1 - 0.18 12.0 1.6 26 5.1 0.0 3.1 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DEAD PF00270.29 KND89517.1 - 0.34 10.7 1.0 5.1 6.8 0.0 3.0 4 0 0 4 4 4 0 DEAD/DEAH box helicase AAA_22 PF13401.6 KND89518.1 - 3.2e-12 46.9 0.0 1e-11 45.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND89518.1 - 1.3e-11 45.2 0.0 4e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KND89518.1 - 1.6e-08 35.0 0.0 6.4e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 KND89518.1 - 5.6e-07 29.5 0.1 2.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 KND89518.1 - 4.1e-06 27.2 0.0 0.001 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 KND89518.1 - 1.3e-05 25.2 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 KND89518.1 - 0.0019 17.6 0.0 0.005 16.3 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein AAA_30 PF13604.6 KND89518.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KND89518.1 - 0.013 14.7 0.0 0.038 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 KND89518.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KND89518.1 - 0.069 12.9 1.0 0.79 9.4 0.0 2.7 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Ploopntkinase3 PF18751.1 KND89518.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 KND89518.1 - 0.13 12.7 0.2 0.4 11.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Auxin_repressed PF05564.12 KND89518.1 - 7.2 7.3 6.2 12 6.6 0.6 3.0 2 1 0 2 2 2 0 Dormancy/auxin associated protein TspO_MBR PF03073.15 KND89519.1 - 1.2e-45 154.9 5.7 1.5e-45 154.6 5.7 1.0 1 0 0 1 1 1 1 TspO/MBR family HSCB_C PF07743.13 KND89520.1 - 3.7e-17 62.6 1.3 3.7e-17 62.6 1.3 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KND89520.1 - 1.7e-06 28.1 0.8 3.9e-06 26.9 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1353 PF07087.11 KND89520.1 - 0.083 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Arrestin_N PF00339.29 KND89521.1 - 3.5e-15 56.3 0.0 1.3e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain WSC PF01822.19 KND89522.1 - 4.7e-18 65.2 8.2 6.4e-18 64.7 8.2 1.2 1 0 0 1 1 1 1 WSC domain IMS PF00817.20 KND89523.1 - 9.9e-39 132.7 0.0 2e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KND89523.1 - 6.1e-27 93.9 1.2 1.3e-26 92.8 1.2 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KND89523.1 - 2.6e-12 47.5 0.0 5.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 KND89523.1 - 1.9e-09 36.7 14.0 3.2e-05 23.2 1.2 4.0 4 0 0 4 4 4 2 Ubiquitin binding region BRCT_2 PF16589.5 KND89523.1 - 2e-08 34.5 0.0 1.5e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KND89523.1 - 0.00024 21.4 0.0 0.00052 20.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 KND89523.1 - 0.00089 19.5 0.0 0.0066 16.7 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 KND89523.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 KND89523.1 - 0.0019 18.5 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain DUF1805 PF08827.11 KND89523.1 - 0.033 14.5 0.0 0.27 11.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) ADSL_C PF10397.9 KND89523.1 - 0.041 14.4 0.0 0.16 12.5 0.0 2.0 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus HHH_5 PF14520.6 KND89523.1 - 0.044 14.4 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain SHR3_chaperone PF08229.11 KND89524.1 - 2.5e-75 251.6 0.0 2.9e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 KND89524.1 - 0.047 13.5 0.2 7.4 6.3 0.1 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF5453 PF17534.2 KND89524.1 - 7.9 6.4 5.9 3.9 7.4 2.3 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5453) DUF3712 PF12505.8 KND89525.1 - 2.8e-21 76.1 2.1 2.8e-21 76.1 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) TamB PF04357.13 KND89525.1 - 0.017 14.4 3.6 0.74 9.0 0.1 2.3 1 1 1 2 2 2 0 TamB, inner membrane protein subunit of TAM complex Baculo_11_kDa PF06143.11 KND89525.1 - 0.035 13.7 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family FMN_dh PF01070.18 KND89526.1 - 4.5e-95 318.6 0.0 5.6e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KND89526.1 - 9.5e-19 67.3 0.0 1.9e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KND89526.1 - 1.1e-06 27.9 0.0 0.00056 19.0 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KND89526.1 - 6.8e-06 25.5 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribul_P_3_epim PF00834.19 KND89526.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family WH2 PF02205.20 KND89527.1 - 6.5e-09 35.3 0.2 6.5e-09 35.3 0.2 2.4 3 0 0 3 3 3 1 WH2 motif Ribosomal_L37 PF08561.10 KND89529.1 - 5.6e-41 139.8 3.5 7.4e-41 139.4 3.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 adh_short PF00106.25 KND89531.1 - 3.9e-16 59.1 0.0 2.2e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KND89531.1 - 0.00037 20.5 0.2 0.00055 19.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND89531.1 - 0.016 14.7 0.1 0.035 13.6 0.1 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Abhydrolase_1 PF00561.20 KND89533.1 - 5.3e-19 68.9 0.1 1.6e-18 67.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND89533.1 - 7.4e-14 52.9 0.2 1.1e-13 52.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND89533.1 - 1.2e-12 47.7 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KND89533.1 - 0.00035 19.4 0.0 0.00066 18.5 0.0 1.4 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 KND89533.1 - 0.00037 19.5 0.0 0.00065 18.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KND89533.1 - 0.0013 18.5 0.6 0.0044 16.8 0.6 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 KND89533.1 - 0.0019 18.0 0.0 0.0082 15.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND89533.1 - 0.0041 16.6 0.2 3.5 7.0 0.1 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF915 PF06028.11 KND89533.1 - 0.023 14.0 0.4 0.26 10.6 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 KND89533.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF5560 PF17715.1 KND89534.1 - 0.59 9.6 6.9 2 7.8 1.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5560) Sortilin-Vps10 PF15902.5 KND89535.1 - 3.9e-289 958.7 27.3 1.2e-148 495.6 13.8 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KND89535.1 - 5e-78 261.3 30.0 2.5e-45 154.9 11.2 3.3 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KND89535.1 - 5.5e-13 46.8 38.3 0.56 10.4 0.0 11.8 11 0 0 11 11 11 8 BNR/Asp-box repeat PSII_BNR PF14870.6 KND89535.1 - 3.7e-05 23.1 0.7 0.39 9.9 0.0 5.4 5 1 1 6 6 6 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KND89535.1 - 0.0044 17.0 2.8 5.4 7.1 0.1 5.1 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 KND89535.1 - 0.0099 15.9 20.1 0.34 11.1 0.1 8.0 8 0 0 8 8 8 1 BNR-Asp box repeat CSS-motif PF12792.7 KND89535.1 - 0.049 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 CSS motif domain associated with EAL DUF2561 PF10812.8 KND89535.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) p450 PF00067.22 KND89536.1 - 4.3e-51 174.1 0.0 1.3e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Vezatin PF12632.7 KND89537.1 - 5.7e-76 255.5 0.1 1.1e-75 254.7 0.1 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes CD99L2 PF12301.8 KND89537.1 - 0.048 14.0 0.1 0.89 9.8 0.0 2.5 2 0 0 2 2 2 0 CD99 antigen like protein 2 PBP_N PF17093.5 KND89537.1 - 2.5 8.4 6.8 0.76 10.0 2.0 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus PCNA_N PF00705.18 KND89538.1 - 3.6e-57 191.5 5.3 7.3e-57 190.6 4.5 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KND89538.1 - 2.6e-49 166.6 0.1 1.4e-48 164.3 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KND89538.1 - 7.6e-10 38.7 0.1 9.2e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 KND89538.1 - 7e-08 31.9 1.1 4.8e-06 25.9 1.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 KND89538.1 - 2.9e-06 26.6 0.3 0.00015 21.0 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein DNA_pol3_beta_3 PF02768.15 KND89538.1 - 0.006 16.4 0.8 0.031 14.1 0.1 2.4 2 2 1 3 3 3 1 DNA polymerase III beta subunit, C-terminal domain Phos_pyr_kin PF08543.12 KND89539.1 - 2.7e-12 46.6 0.0 5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KND89539.1 - 1e-08 34.9 1.0 8.6e-08 31.8 0.0 2.4 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Tim17 PF02466.19 KND89541.1 - 2.9e-13 50.2 0.1 5e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4817 PF16087.5 KND89543.1 - 0.022 14.6 0.0 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) HECT_2 PF09814.9 KND89544.1 - 3.7e-95 319.0 0.0 6.7e-95 318.1 0.0 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.23 KND89544.1 - 1.7e-33 115.8 0.0 5.4e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KND89544.1 - 1.3e-07 31.9 0.1 2.7e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND89544.1 - 0.018 15.1 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-ISL3 PF14690.6 KND89544.1 - 0.046 14.4 0.2 0.2 12.3 0.2 2.2 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Sulfate_transp PF00916.20 KND89545.1 - 1.1e-52 179.1 10.6 1.6e-52 178.5 10.6 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KND89545.1 - 4.5e-16 58.7 0.0 9.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KND89545.1 - 2.4e-09 36.8 0.0 5.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF5389 PF17364.2 KND89545.1 - 0.49 10.5 2.9 2.7 8.1 0.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5389) Sld5 PF05916.11 KND89546.1 - 6.1e-12 46.0 0.0 8.5e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 KND89546.1 - 0.051 14.4 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FliT DUF3405 PF11885.8 KND89547.1 - 5.6e-229 761.0 2.8 6.6e-229 760.8 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 KND89548.1 - 9.3e-45 152.8 0.0 1.1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NuiA PF07924.11 KND89548.1 - 0.081 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Arf PF00025.21 KND89549.1 - 8.3e-80 266.3 0.2 9.6e-80 266.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND89549.1 - 4.1e-14 52.8 0.0 5.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND89549.1 - 4.3e-14 52.3 0.0 5.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KND89549.1 - 1.4e-13 50.8 1.2 1.3e-09 37.8 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND89549.1 - 3e-13 49.7 0.0 3.4e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KND89549.1 - 6.1e-10 38.8 0.0 7.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND89549.1 - 8.5e-06 25.8 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KND89549.1 - 0.0073 15.6 0.3 0.025 13.9 0.1 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_2 PF07724.14 KND89550.1 - 4.4e-45 153.9 0.1 5.9e-44 150.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KND89550.1 - 4.5e-35 119.7 1.9 4.5e-35 119.7 1.9 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KND89550.1 - 7.8e-24 83.5 0.1 2.6e-23 81.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KND89550.1 - 5e-19 69.0 0.1 4.8e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND89550.1 - 2.2e-13 50.4 0.1 6.9e-09 35.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND89550.1 - 1.2e-09 38.8 3.4 0.00087 19.7 0.1 4.1 2 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KND89550.1 - 1.5e-07 31.3 0.2 0.00055 19.7 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KND89550.1 - 1.1e-06 28.9 0.9 0.12 12.7 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KND89550.1 - 4.5e-05 23.5 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KND89550.1 - 6.6e-05 22.9 6.4 0.48 10.3 0.0 4.2 3 2 1 5 5 5 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KND89550.1 - 6.9e-05 22.8 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 KND89550.1 - 7.5e-05 22.2 0.1 0.045 13.2 0.1 3.5 3 1 0 3 3 2 1 Bacterial TniB protein AAA_23 PF13476.6 KND89550.1 - 7.5e-05 23.3 7.7 0.065 13.7 4.3 3.3 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KND89550.1 - 0.00014 21.4 0.0 0.64 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KND89550.1 - 0.00035 20.4 0.2 0.57 9.9 0.0 2.9 2 1 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 KND89550.1 - 0.0015 19.1 1.5 0.27 11.7 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 KND89550.1 - 0.0021 18.6 1.3 0.27 11.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KND89550.1 - 0.0038 17.5 0.3 6 7.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 KND89550.1 - 0.0048 16.8 0.8 1.7 8.6 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase Mg_chelatase PF01078.21 KND89550.1 - 0.0058 16.0 0.1 2.6 7.4 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ERM PF00769.19 KND89550.1 - 0.0062 16.4 5.2 0.012 15.4 5.2 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family PhoH PF02562.16 KND89550.1 - 0.0067 15.9 0.1 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.22 KND89550.1 - 0.007 16.7 0.0 1 9.8 0.0 2.9 2 1 0 2 2 2 1 RNA helicase Roc PF08477.13 KND89550.1 - 0.0078 16.4 0.1 3.2 8.0 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KND89550.1 - 0.01 15.6 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND89550.1 - 0.013 15.7 0.0 5.9 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KND89550.1 - 0.014 15.4 0.0 10 6.1 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KND89550.1 - 0.014 15.1 0.1 0.52 10.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 KND89550.1 - 0.018 14.7 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KND89550.1 - 0.03 14.1 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 KND89550.1 - 0.03 14.3 0.7 27 4.7 0.0 3.6 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit HBM PF16591.5 KND89550.1 - 0.034 13.6 0.6 0.066 12.6 0.6 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF815 PF05673.13 KND89550.1 - 0.037 13.2 0.5 1.1 8.4 0.3 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 KND89550.1 - 0.041 13.5 0.1 0.82 9.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 KND89550.1 - 0.043 13.1 0.0 2.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin UvrD-helicase PF00580.21 KND89550.1 - 0.048 13.2 1.9 0.5 9.8 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DNA_topoisoIV PF00521.20 KND89550.1 - 0.06 12.2 2.2 0.1 11.5 2.2 1.3 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A AAA_15 PF13175.6 KND89550.1 - 0.065 12.9 3.3 0.7 9.5 0.9 2.4 2 0 0 2 2 2 0 AAA ATPase domain CENP-F_leu_zip PF10473.9 KND89550.1 - 0.074 13.1 13.6 0.31 11.0 13.6 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_19 PF13245.6 KND89550.1 - 0.14 12.5 2.5 1.3 9.3 0.1 3.2 2 2 1 3 3 3 0 AAA domain DUF3782 PF12644.7 KND89550.1 - 0.16 12.2 2.5 0.73 10.0 1.6 2.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3782) AAA_29 PF13555.6 KND89550.1 - 0.19 11.5 0.2 7.9 6.3 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KND89550.1 - 0.36 10.6 3.9 1.3 8.8 0.1 3.3 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system PKcGMP_CC PF16808.5 KND89550.1 - 0.53 10.2 8.0 1.8 8.5 1.0 3.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 KND89550.1 - 0.83 9.0 3.2 1.4 8.2 3.2 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4446 PF14584.6 KND89550.1 - 1.2 9.1 3.4 3.1 7.8 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.22 KND89550.1 - 2.3 8.5 14.4 7.1 6.9 12.0 2.9 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain CR6_interact PF10147.9 KND89550.1 - 2.3 7.9 9.5 4.2 7.0 9.5 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GrpE PF01025.19 KND89550.1 - 2.7 7.6 11.5 5.4 6.7 9.9 2.2 2 0 0 2 2 2 0 GrpE DUF4337 PF14235.6 KND89550.1 - 3.2 7.9 5.1 5.8 7.0 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FapA PF03961.13 KND89550.1 - 4.1 5.9 8.7 8.5 4.9 8.7 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 KND89550.1 - 6.7 5.7 7.6 13 4.7 7.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Proteasom_Rpn13 PF04683.13 KND89551.1 - 8.9e-26 90.3 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KND89551.1 - 2.3e-11 43.9 0.3 3.4e-10 40.1 0.3 2.3 1 1 0 1 1 1 1 UCH-binding domain L27_2 PF09045.10 KND89551.1 - 0.0082 16.1 0.1 0.018 15.0 0.1 1.5 1 0 0 1 1 1 1 L27_2 RRM_1 PF00076.22 KND89552.1 - 6e-10 38.8 0.0 0.00067 19.4 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND89552.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF4267 PF14087.6 KND89553.1 - 1.2e-25 89.7 3.6 1.4e-25 89.5 3.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DEAD PF00270.29 KND89554.1 - 3.2e-46 157.3 0.0 4.9e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND89554.1 - 9e-32 109.7 0.1 2.5e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND89554.1 - 5.3e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ARGLU PF15346.6 KND89554.1 - 0.086 12.7 2.9 0.15 11.9 2.9 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Aldo_ket_red PF00248.21 KND89555.1 - 8.4e-44 149.9 0.0 5e-42 144.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.11 KND89556.1 - 0.00021 20.9 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 KND89556.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) HIT PF01230.23 KND89557.1 - 2.1e-18 66.9 0.1 4.6e-18 65.8 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KND89557.1 - 1.5e-06 28.6 0.0 4.1e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KND89557.1 - 0.00044 20.1 0.0 0.00087 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 KND89558.1 - 2.9e-11 42.8 1.1 3.9e-11 42.4 1.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.10 KND89558.1 - 0.0021 18.1 0.6 0.0048 17.0 0.6 1.6 1 1 0 1 1 1 1 Zinc ribbon domain Lar_restr_allev PF14354.6 KND89558.1 - 0.005 17.2 0.9 0.43 11.0 0.1 2.1 1 1 1 2 2 2 1 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 KND89558.1 - 0.0076 16.5 0.8 0.015 15.5 0.8 1.5 1 1 0 1 1 1 1 zinc-ribbon A2L_zn_ribbon PF08792.10 KND89558.1 - 0.0076 15.9 0.5 0.012 15.3 0.5 1.2 1 0 0 1 1 1 1 A2L zinc ribbon domain zf-C2HC5 PF06221.13 KND89558.1 - 0.016 15.2 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type PhnA_Zn_Ribbon PF08274.12 KND89558.1 - 0.022 14.7 0.3 0.036 14.0 0.3 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DnaJ_CXXCXGXG PF00684.19 KND89558.1 - 0.03 14.7 0.7 0.042 14.2 0.7 1.4 1 0 0 1 1 1 0 DnaJ central domain HypA PF01155.19 KND89558.1 - 0.035 14.1 0.2 0.04 13.9 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 KND89558.1 - 0.045 13.3 0.4 2 8.0 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding GFA PF04828.14 KND89558.1 - 0.05 13.9 0.5 3.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_SprT PF17283.2 KND89558.1 - 0.077 12.9 1.6 0.22 11.5 1.3 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KND89558.1 - 0.12 12.3 2.4 0.13 12.3 0.2 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain YacG PF03884.14 KND89558.1 - 0.12 12.1 0.4 0.59 9.9 0.0 2.2 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG CIAPIN1 PF05093.13 KND89559.1 - 5.3e-38 129.6 3.9 9e-38 128.8 3.9 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KND89559.1 - 3.9e-29 101.6 0.0 5.4e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus TPR_17 PF13431.6 KND89560.1 - 0.013 15.8 1.1 69 4.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND89560.1 - 0.073 13.6 2.1 7.1 7.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND89560.1 - 0.17 12.8 7.9 24 6.1 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 KND89560.1 - 0.85 10.3 6.8 6.6 7.5 2.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 KND89560.1 - 1.7 8.4 4.7 25 4.7 0.2 3.8 3 0 0 3 3 3 0 TPR repeat ChAPs PF09295.10 KND89561.1 - 5.2e-151 503.1 0.0 7.9e-151 502.5 0.0 1.3 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ATP_bind_1 PF03029.17 KND89561.1 - 2.1e-69 234.0 0.0 4.8e-69 232.8 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein TPR_8 PF13181.6 KND89561.1 - 8e-05 22.6 0.1 0.13 12.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND89561.1 - 0.00017 21.4 0.6 0.57 10.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND89561.1 - 0.00039 20.5 0.3 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND89561.1 - 0.00039 20.1 1.0 0.57 10.1 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND89561.1 - 0.00049 20.0 4.9 0.025 14.7 1.2 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat AAA_24 PF13479.6 KND89561.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND89561.1 - 0.0026 18.0 0.0 0.0085 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND89561.1 - 0.004 16.2 0.0 0.97 8.4 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KND89561.1 - 0.0065 16.1 0.0 0.2 11.2 0.0 3.1 3 1 1 4 4 4 1 SRP54-type protein, GTPase domain TPR_14 PF13428.6 KND89561.1 - 0.0067 17.2 6.1 0.37 11.7 0.8 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat NB-ARC PF00931.22 KND89561.1 - 0.007 15.6 0.5 0.023 13.9 0.0 2.1 3 0 0 3 3 3 1 NB-ARC domain AAA_33 PF13671.6 KND89561.1 - 0.0099 16.0 0.0 0.065 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND89561.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KND89561.1 - 0.013 15.3 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KND89561.1 - 0.014 14.9 0.0 0.44 10.1 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KND89561.1 - 0.022 14.5 0.0 4.4 7.1 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 KND89561.1 - 0.031 14.3 0.0 0.38 10.8 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KND89561.1 - 0.035 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KND89561.1 - 0.08 12.1 0.0 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit cobW PF02492.19 KND89561.1 - 0.08 12.5 0.0 0.5 9.9 0.0 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KND89561.1 - 0.1 12.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 KND89561.1 - 0.1 13.1 0.5 1.4 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KND89561.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 KND89561.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_6 PF13174.6 KND89561.1 - 0.21 12.3 0.6 74 4.3 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat NDUFB10 PF10249.9 KND89562.1 - 0.015 15.8 0.0 0.02 15.4 0.0 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Glyoxalase PF00903.25 KND89564.1 - 3.6e-09 36.9 0.0 6.2e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KND89564.1 - 2.5e-05 24.5 0.1 0.0001 22.5 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KND89564.1 - 0.00024 21.4 0.0 0.00031 21.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KND89564.1 - 0.012 16.4 0.6 0.046 14.5 0.6 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain Tyrosinase PF00264.20 KND89565.1 - 2.7e-44 152.1 2.7 4e-44 151.5 2.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KND89565.1 - 0.00019 22.1 0.0 0.00084 20.0 0.0 2.0 1 1 0 1 1 1 1 Tyosinase C-terminal domain AMP-binding PF00501.28 KND89566.1 - 1.6e-169 564.0 0.9 4.1e-68 229.9 0.0 3.5 3 1 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KND89566.1 - 4.1e-105 352.1 0.0 1.6e-35 122.7 0.0 5.1 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.25 KND89566.1 - 9.5e-31 106.0 0.6 2.1e-12 47.2 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KND89566.1 - 1e-09 39.2 2.6 0.04 14.9 0.1 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 KND89566.1 - 0.0041 17.1 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 1 Cyclophilin-like family BTB PF00651.31 KND89567.1 - 0.0015 18.7 0.0 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Coatomer_E PF04733.14 KND89568.1 - 2.6e-60 204.3 3.5 3.1e-60 204.1 3.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KND89568.1 - 7.6e-08 32.7 17.3 0.00055 20.4 0.6 3.2 4 1 1 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND89568.1 - 4e-05 23.8 0.7 0.2 11.9 0.3 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KND89568.1 - 0.00015 21.1 1.5 0.0079 15.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND89568.1 - 0.0013 19.0 8.8 0.22 11.8 1.4 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND89568.1 - 0.0015 18.2 0.7 0.43 10.5 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND89568.1 - 0.0027 18.2 1.5 1.9 9.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KND89568.1 - 0.004 17.2 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat TPR_2 PF07719.17 KND89568.1 - 0.0044 17.0 8.6 0.019 15.0 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND89568.1 - 0.0057 17.4 13.3 0.32 11.9 0.3 5.4 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND89568.1 - 0.0082 16.3 0.2 1.7 9.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Type_III_YscG PF09477.10 KND89568.1 - 0.02 14.9 3.6 2.8 8.0 0.0 3.6 1 1 2 3 3 3 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_16 PF13432.6 KND89568.1 - 0.28 11.9 13.1 3.2 8.5 1.1 3.9 2 1 3 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND89568.1 - 1.3 9.8 20.1 1.2 10.0 0.2 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat FYVE PF01363.21 KND89569.1 - 4.1e-23 81.3 20.4 8.8e-17 61.0 8.5 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KND89569.1 - 9.5e-18 63.7 1.6 2.3e-17 62.4 1.6 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 KND89569.1 - 0.0005 20.3 6.2 0.035 14.4 0.1 2.8 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 KND89569.1 - 0.0006 19.9 1.8 0.0006 19.9 1.8 4.0 4 1 1 5 5 4 1 AN1-like Zinc finger TMF_TATA_bd PF12325.8 KND89569.1 - 0.0029 17.8 1.9 0.0029 17.8 1.9 2.8 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF2225 PF09986.9 KND89569.1 - 0.072 12.8 3.3 0.12 12.0 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) HypA PF01155.19 KND89569.1 - 0.42 10.7 11.5 2.3 8.3 3.7 3.7 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ABC_tran_CTD PF16326.5 KND89569.1 - 0.57 10.5 4.8 3.7 7.9 1.7 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain Rad50_zn_hook PF04423.14 KND89569.1 - 0.58 10.0 2.7 4.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 KND89569.1 - 0.66 9.9 2.5 17 5.3 0.0 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) TolA_bind_tri PF16331.5 KND89569.1 - 1.3 9.2 4.8 1.1 9.4 0.2 3.1 3 1 0 3 3 3 0 TolA binding protein trimerisation zf-C2H2_4 PF13894.6 KND89569.1 - 1.4 10.0 0.0 1.4 10.0 0.0 5.7 5 1 1 6 6 5 0 C2H2-type zinc finger Uds1 PF15456.6 KND89569.1 - 1.4 9.1 5.3 6.8 6.9 0.1 3.7 4 0 0 4 4 4 0 Up-regulated During Septation C6_DPF PF10170.9 KND89569.1 - 2.3 8.7 6.6 0.23 11.8 0.4 2.5 2 1 0 2 2 2 0 Cysteine-rich domain zinc_ribbon_9 PF14369.6 KND89569.1 - 5.5 7.3 9.4 2 8.8 0.1 3.7 4 0 0 4 4 3 0 zinc-ribbon zf-NADH-PPase PF09297.11 KND89569.1 - 9.6 6.0 14.7 2.1 8.1 0.1 4.2 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain NAD_binding_7 PF13241.6 KND89570.1 - 3.2e-30 104.6 0.1 5.2e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KND89570.1 - 7.6e-28 96.0 0.0 1.1e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KND89570.1 - 4.5e-14 51.6 0.1 6.9e-14 51.0 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KND89570.1 - 0.00058 19.2 0.0 0.00073 18.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cytotoxic PF09000.10 KND89570.1 - 0.0025 18.1 0.2 0.099 13.0 0.1 2.2 2 0 0 2 2 2 1 Cytotoxic TrkA_N PF02254.18 KND89570.1 - 0.016 15.5 0.2 0.025 14.8 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 KND89570.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CENP-L PF13092.6 KND89571.1 - 2.4e-53 180.7 0.0 2.1e-51 174.4 0.0 2.1 2 0 0 2 2 2 2 Kinetochore complex Sim4 subunit Fta1 5_nucleotid_C PF02872.18 KND89572.1 - 4.2e-37 127.8 0.0 7.2e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KND89572.1 - 0.0045 17.5 0.0 0.016 15.7 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase MBF1 PF08523.10 KND89573.1 - 1.3e-25 89.6 0.8 1.3e-25 89.6 0.8 1.5 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KND89573.1 - 4.8e-10 39.4 0.0 7.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KND89573.1 - 0.00036 20.8 0.0 0.00062 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.9 KND89573.1 - 0.042 13.7 0.1 0.055 13.3 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_37 PF13744.6 KND89573.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 KND89573.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1365 PF07103.11 KND89574.1 - 6.8e-58 196.2 0.0 1e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) GFA PF04828.14 KND89575.1 - 3e-25 88.4 0.0 4.4e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 KND89575.1 - 0.21 11.6 3.4 1.6 8.8 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon OTT_1508_deam PF14441.6 KND89576.1 - 2.2e-19 69.2 2.0 2.2e-19 69.2 2.0 2.6 2 0 0 2 2 2 2 OTT_1508-like deaminase adh_short_C2 PF13561.6 KND89579.1 - 3.2e-55 187.2 2.2 4.2e-55 186.8 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND89579.1 - 2.6e-41 141.2 1.6 3.6e-41 140.8 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND89579.1 - 7.5e-15 55.3 1.2 1e-14 54.8 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND89579.1 - 9.7e-05 21.9 0.1 0.00015 21.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND89579.1 - 0.00019 20.5 0.1 0.00027 20.0 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KND89579.1 - 0.00079 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KND89579.1 - 0.00089 18.7 0.1 0.0018 17.7 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KND89579.1 - 0.0035 17.2 0.6 0.0057 16.6 0.6 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KND89579.1 - 0.013 15.7 0.1 0.032 14.5 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 KND89579.1 - 0.056 13.7 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.21 KND89579.1 - 0.089 12.1 0.5 0.84 8.9 0.2 2.1 2 0 0 2 2 2 0 ThiF family AAA_22 PF13401.6 KND89580.1 - 0.0016 18.7 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND89580.1 - 0.0073 16.7 0.0 0.27 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain 3-alpha PF03475.14 KND89580.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 3-alpha domain Zeta_toxin PF06414.12 KND89580.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 KND89580.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GST_N_3 PF13417.6 KND89581.1 - 5e-19 68.5 0.1 1.4e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND89581.1 - 2.3e-18 66.3 0.1 1.4e-17 63.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KND89581.1 - 5e-11 42.8 0.1 9e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND89581.1 - 1.9e-08 34.2 0.0 3.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND89581.1 - 0.0057 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KND89581.1 - 0.18 12.4 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RrnaAD PF00398.20 KND89582.1 - 6.1e-62 209.1 0.0 7.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KND89582.1 - 8.8e-07 29.5 0.0 2.1e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND89582.1 - 1.4e-05 25.6 0.0 3.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND89582.1 - 0.00039 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KND89582.1 - 0.00091 19.9 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND89582.1 - 0.0054 16.5 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KND89582.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND89582.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KND89582.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 KND89582.1 - 0.16 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PRP1_N PF06424.12 KND89583.1 - 6.8e-50 169.3 8.2 1.5e-49 168.2 8.2 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 KND89583.1 - 5.3e-27 94.1 10.5 0.00016 22.1 0.0 9.7 6 3 2 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 KND89583.1 - 2.6e-25 86.9 32.5 0.084 13.7 0.5 14.0 6 3 8 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.6 KND89583.1 - 1.8e-09 38.1 13.5 0.048 14.3 0.0 8.2 6 2 2 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KND89583.1 - 2e-09 37.2 4.4 9.1 6.9 0.0 9.8 10 1 2 12 12 12 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND89583.1 - 5.7e-09 35.4 9.2 0.08 13.1 0.0 9.1 11 1 1 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND89583.1 - 1e-08 34.7 3.1 0.17 12.2 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 KND89583.1 - 1.1e-05 25.2 2.4 0.16 11.7 0.1 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 KND89583.1 - 1.3e-05 24.8 0.1 0.43 10.5 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KND89583.1 - 4.1e-05 22.7 4.8 1.2 8.0 0.0 5.4 3 1 4 7 7 7 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.6 KND89583.1 - 0.00039 20.0 1.4 1.6 8.5 0.0 5.2 6 0 0 6 6 6 1 TPR repeat TPR_9 PF13371.6 KND89583.1 - 0.00049 20.2 10.8 0.018 15.2 0.0 5.9 5 2 2 7 7 7 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KND89583.1 - 0.0022 17.9 4.3 2.1 8.2 0.1 4.8 3 2 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 KND89583.1 - 0.12 11.1 0.1 3.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) Vac7 PF12751.7 KND89585.1 - 7.6e-160 532.5 8.1 7.6e-160 532.5 8.1 2.3 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 zf-PHD-like PF15446.6 KND89587.1 - 5e-71 237.8 11.1 9.3e-71 236.9 11.1 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KND89587.1 - 3.9e-46 157.4 0.0 6.7e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND89587.1 - 1.3e-18 67.3 0.0 3.6e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KND89587.1 - 4.5e-07 29.3 3.6 1.1e-06 28.1 3.6 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KND89587.1 - 2.7e-06 27.2 0.2 0.00021 21.2 0.2 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KND89587.1 - 5.9e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KND89587.1 - 0.00013 21.8 7.7 0.00013 21.8 7.7 3.3 2 2 1 3 3 3 1 PHD-finger DEAD PF00270.29 KND89587.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 KND89587.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KND89587.1 - 0.14 12.5 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MutS_III PF05192.18 KND89587.1 - 0.24 11.6 1.5 24 5.1 0.0 2.8 2 1 0 2 2 2 0 MutS domain III PHD_2 PF13831.6 KND89587.1 - 1.4 8.6 13.7 0.011 15.3 3.1 2.9 3 0 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 KND89587.1 - 1.4 8.9 9.7 0.35 10.8 5.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 KND89587.1 - 8.9 6.5 13.7 10 6.3 0.8 3.2 2 1 0 2 2 2 0 KIAA1045 RING finger Complex1_LYR PF05347.15 KND89589.1 - 7.9e-09 35.4 0.4 9.9e-08 31.9 0.4 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND89589.1 - 0.054 14.2 0.4 0.054 14.2 0.4 1.8 2 1 0 2 2 2 0 Complex1_LYR-like SpoU_methylase PF00588.19 KND89591.1 - 8.9e-21 74.5 0.0 1.6e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 KND89591.1 - 1.6e-10 41.1 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Ank_4 PF13637.6 KND89592.1 - 1.7e-16 60.3 0.6 3.9e-09 36.9 0.1 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND89592.1 - 1.2e-11 43.7 0.2 0.00056 20.2 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KND89592.1 - 2.6e-11 44.0 0.0 0.0016 19.0 0.0 3.6 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KND89592.1 - 9.9e-11 41.6 2.8 0.0013 19.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KND89592.1 - 1.2e-05 25.5 0.3 0.1 12.9 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KND89592.1 - 0.00011 22.0 0.8 0.00069 19.4 0.4 2.3 2 1 0 2 2 2 1 KilA-N domain Exonuc_VII_L PF02601.15 KND89592.1 - 0.11 12.0 4.7 0.24 10.9 4.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliJ PF02050.16 KND89592.1 - 0.57 10.4 7.3 2.1 8.6 7.3 2.0 1 0 0 1 1 1 0 Flagellar FliJ protein Hrs_helical PF12210.8 KND89592.1 - 0.58 10.7 4.2 6.7 7.3 4.1 2.3 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate OmpH PF03938.14 KND89592.1 - 0.88 9.9 5.1 2.1 8.7 5.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Muted PF14942.6 KND89592.1 - 3.9 7.8 5.9 8.5 6.7 5.9 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein AA_permease_2 PF13520.6 KND89593.1 - 5.9e-84 282.3 33.1 8.1e-84 281.9 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND89593.1 - 1.3e-15 57.0 27.3 1.8e-15 56.5 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease PsbN PF02468.15 KND89593.1 - 0.048 13.5 1.9 0.3 11.0 1.9 2.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) AltA1 PF16541.5 KND89594.1 - 4.1e-27 95.2 0.9 4.1e-27 95.2 0.9 1.6 2 0 0 2 2 2 1 Alternaria alternata allergen 1 MFS_1 PF07690.16 KND89595.1 - 1.4e-33 116.3 27.2 1.4e-33 116.3 27.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 KND89595.1 - 0.69 10.2 7.0 56 4.0 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Cyt-b5 PF00173.28 KND89597.1 - 2.3e-10 40.4 0.1 3.1e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_4 PF13894.6 KND89602.1 - 0.13 13.1 0.1 0.13 13.1 0.1 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger DUF4716 PF15837.5 KND89602.1 - 0.32 11.1 1.4 0.57 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) zf-C2H2 PF00096.26 KND89602.1 - 9.1 7.0 18.5 1.5 9.4 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 KND89604.1 - 0.00023 21.4 18.6 0.0024 18.2 4.0 8.2 8 1 0 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KND89604.1 - 0.0061 16.8 29.8 0.43 10.9 1.9 6.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KND89604.1 - 0.0074 16.9 0.3 0.0074 16.9 0.3 5.1 3 2 3 6 6 6 1 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KND89604.1 - 0.12 12.4 24.9 0.44 10.6 1.0 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KND89604.1 - 0.12 13.3 0.4 0.12 13.3 0.4 8.9 8 2 0 8 8 8 0 C2H2-type zinc finger AAA PF00004.29 KND89605.1 - 2.5e-16 60.3 0.0 4e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_12 PF13424.6 KND89606.1 - 2.9e-10 40.3 1.8 0.016 15.5 0.0 4.3 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND89606.1 - 0.00032 20.6 2.8 0.58 10.4 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND89606.1 - 0.00033 20.4 4.8 1.5 8.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND89606.1 - 0.0035 17.3 0.1 0.16 12.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TerY_C PF15616.6 KND89606.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain FANCI_S1 PF14675.6 KND89606.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 DUF4175 PF13779.6 KND89607.1 - 0.066 11.1 0.5 0.074 11.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF883 PF05957.13 KND89607.1 - 2 9.0 4.8 0.78 10.4 2.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) JAB PF01398.21 KND89608.1 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KND89608.1 - 2.3e-18 66.6 0.7 4.5e-18 65.7 0.3 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KND89608.1 - 0.029 14.4 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) SUZ PF12752.7 KND89609.1 - 9.8e-13 48.7 2.8 9.8e-13 48.7 2.8 2.9 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 KND89609.1 - 3e-08 33.5 0.1 7.1e-08 32.3 0.1 1.7 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.19 KND89610.1 - 3.1e-30 104.9 0.9 7.8e-30 103.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 tRNA-Thr_ED PF08915.11 KND89610.1 - 3.3 7.8 5.6 1.1 9.3 1.2 2.1 2 1 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase UTP25 PF06862.12 KND89611.1 - 6.4e-197 655.0 0.0 7.6e-197 654.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KND89611.1 - 0.00021 21.1 0.0 0.0053 16.5 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase APH_6_hur PF04655.14 KND89611.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase SDA1 PF05285.12 KND89611.1 - 8.9 5.6 16.7 19 4.6 16.7 1.5 1 0 0 1 1 1 0 SDA1 ALAD PF00490.21 KND89612.1 - 2.1e-122 408.2 0.0 2.5e-122 408.0 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AIM5 PF17050.5 KND89613.1 - 4.8e-22 78.5 3.1 4.8e-22 78.5 3.1 2.9 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 Tox-MPTase2 PF15638.6 KND89613.1 - 0.17 11.6 0.0 0.52 10.0 0.0 1.8 1 1 0 1 1 1 0 Metallopeptidase toxin 2 YtxH PF12732.7 KND89613.1 - 5.5 7.6 13.0 8.1 7.1 2.2 2.9 2 1 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 KND89613.1 - 6.3 7.5 15.4 1.3 9.6 1.7 3.2 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Amidohydro_3 PF07969.11 KND89614.1 - 2.9e-70 238.1 5.0 3.6e-70 237.8 5.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KND89614.1 - 0.0041 16.5 0.1 0.076 12.3 0.1 2.6 2 1 0 2 2 2 1 Amidohydrolase family Botulinum_HA-17 PF05588.11 KND89615.1 - 0.0081 16.3 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 Clostridium botulinum HA-17 domain Y_phosphatase3 PF13350.6 KND89616.1 - 1.4e-47 162.6 0.0 1.7e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KND89616.1 - 0.00093 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KND89616.1 - 0.0065 16.1 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase SCP2 PF02036.17 KND89617.1 - 3.1e-25 88.6 0.5 3.5e-25 88.4 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KND89617.1 - 1.6e-05 25.2 0.2 1.9e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KND89617.1 - 0.0052 17.2 0.1 0.0065 16.9 0.1 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain LETM1 PF07766.13 KND89618.1 - 5.9e-12 45.5 0.4 1.9e-10 40.5 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein Zn_clus PF00172.18 KND89619.1 - 8.3e-09 35.4 13.5 1.3e-08 34.8 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KND89621.1 - 1.3e-21 76.4 14.0 2.7e-05 24.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND89621.1 - 4.7e-14 52.5 0.3 0.0018 18.5 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND89621.1 - 0.00059 19.8 0.0 0.12 12.3 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A APG5 PF04106.12 KND89622.1 - 1.9e-44 151.9 0.0 8.7e-44 149.8 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 GAF_2 PF13185.6 KND89624.1 - 6.1e-08 33.0 0.0 9.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KND89624.1 - 0.0066 17.1 0.0 0.0089 16.7 0.0 1.3 1 0 0 1 1 1 1 GAF domain AlaDh_PNT_C PF01262.21 KND89624.1 - 0.049 12.9 0.0 0.38 10.0 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain C2 PF00168.30 KND89625.1 - 2e-15 56.9 0.0 3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain UTP15_C PF09384.10 KND89626.1 - 2.2e-50 170.1 0.0 3.3e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KND89626.1 - 3.6e-18 65.6 2.2 0.00013 22.7 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND89626.1 - 3.1e-08 33.8 0.8 0.02 15.2 0.1 3.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Glyoxal_oxid_N PF07250.11 KND89626.1 - 0.24 10.6 0.6 7.4 5.7 0.1 2.4 2 1 1 3 3 3 0 Glyoxal oxidase N-terminus zf-U1 PF06220.12 KND89628.1 - 1.7e-15 56.5 1.5 2.5e-15 55.9 1.5 1.3 1 0 0 1 1 1 1 U1 zinc finger Sdh5 PF03937.16 KND89629.1 - 1.1e-23 82.9 0.0 3.5e-23 81.4 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase MIS13 PF08202.11 KND89630.1 - 1.2e-60 205.4 0.5 2.7e-60 204.2 0.5 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family ZapB PF06005.12 KND89630.1 - 0.078 13.4 4.4 0.28 11.7 0.2 3.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF966 PF06136.13 KND89630.1 - 0.34 10.6 9.0 0.48 10.1 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DivIC PF04977.15 KND89630.1 - 0.48 10.2 2.4 5.2 6.9 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator EMP24_GP25L PF01105.24 KND89631.1 - 2.1e-40 138.6 0.0 2.6e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MARVEL PF01284.23 KND89632.1 - 4.4e-06 26.8 15.1 5.9e-06 26.4 15.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain NCE101 PF11654.8 KND89632.1 - 0.31 10.8 1.4 4.1 7.2 0.2 2.4 2 0 0 2 2 2 0 Non-classical export protein 1 Peptidase_S10 PF00450.22 KND89633.1 - 7.9e-115 384.6 0.0 1e-114 384.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 KND89633.1 - 0.025 13.9 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RNA_Me_trans PF04252.13 KND89634.1 - 6.7e-82 273.9 0.0 7.5e-82 273.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Aft1_HRR PF11787.8 KND89635.1 - 1.8e-32 112.3 5.7 1.8e-32 112.3 5.7 3.6 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_HRA PF11786.8 KND89635.1 - 2.7e-24 85.3 9.0 2.7e-24 85.3 9.0 3.6 2 2 1 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 KND89635.1 - 2.3e-22 79.2 10.7 2.3e-22 79.2 10.7 4.0 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 KND89635.1 - 1.2e-12 47.8 5.8 1.8e-12 47.1 5.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND89635.1 - 6.5e-06 26.1 6.0 1.2e-05 25.3 6.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KND89635.1 - 0.0026 18.2 3.1 0.0026 18.2 3.1 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor zf-C2H2_10 PF16588.5 KND89636.1 - 0.034 13.9 4.3 0.12 12.2 2.9 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC PF00098.23 KND89636.1 - 0.052 13.7 14.3 0.071 13.2 1.1 4.2 4 0 0 4 4 4 0 Zinc knuckle Baculo_p48 PF04878.13 KND89636.1 - 0.21 10.5 2.8 0.35 9.8 2.8 1.2 1 0 0 1 1 1 0 Baculovirus P48 protein Dynamin_N PF00350.23 KND89637.1 - 1.8e-33 116.0 0.0 4.9e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND89637.1 - 8.8e-29 100.6 0.0 7.5e-26 91.0 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KND89637.1 - 0.0001 22.3 0.1 0.22 11.6 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GED PF02212.18 KND89637.1 - 0.00052 20.1 1.4 0.0038 17.3 0.2 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KND89637.1 - 0.075 12.6 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.6 KND89637.1 - 0.15 11.7 1.0 0.48 10.1 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 KND89637.1 - 0.16 12.3 0.3 1.2 9.5 0.0 2.5 3 1 1 4 4 4 0 AAA ATPase domain MTBP_C PF14920.6 KND89637.1 - 0.46 10.2 4.2 0.29 10.9 0.3 2.3 2 1 0 2 2 2 0 MDM2-binding HEAT PF02985.22 KND89638.1 - 5.9e-11 41.7 0.6 0.13 12.5 0.0 5.3 4 1 1 5 5 5 4 HEAT repeat Cnd1 PF12717.7 KND89638.1 - 5e-07 29.9 0.2 1e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND89638.1 - 8.4e-07 29.3 0.5 0.00025 21.4 0.1 2.4 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 KND89638.1 - 7.1e-06 26.4 0.1 0.022 15.2 0.1 3.3 2 0 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.20 KND89638.1 - 0.0064 15.1 0.2 0.009 14.6 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region NAD_binding_9 PF13454.6 KND89638.1 - 0.065 13.2 0.0 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyridoxal_deC PF00282.19 KND89639.1 - 5.7e-25 87.8 0.0 8.5e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 KND89639.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2462 PF09495.10 KND89640.1 - 1e-15 58.2 8.7 1.4e-15 57.7 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Peptidase_M48 PF01435.18 KND89641.1 - 5.8e-37 127.4 0.0 1.2e-36 126.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Cyt-b5 PF00173.28 KND89642.1 - 4.2e-20 71.7 0.2 4.8e-20 71.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1699 PF08004.11 KND89642.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Methyltransf_23 PF13489.6 KND89643.1 - 6.7e-12 45.5 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89643.1 - 1.7e-07 31.9 0.0 3.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89643.1 - 0.00031 20.6 0.0 0.0026 17.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89643.1 - 0.0026 18.5 0.0 0.0099 16.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND89643.1 - 0.059 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cupin_5 PF06172.11 KND89644.1 - 8.6e-48 162.1 0.0 1e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Aconitase PF00330.20 KND89646.1 - 5e-145 484.0 0.0 6.8e-145 483.6 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KND89646.1 - 7.2e-37 126.7 0.0 1.3e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Nucleopor_Nup85 PF07575.13 KND89646.1 - 4e-16 58.7 0.9 4.5e-11 42.0 0.0 2.5 3 0 0 3 3 3 2 Nup85 Nucleoporin Hep_59 PF07052.11 KND89646.1 - 0.34 11.7 6.5 0.81 10.5 6.5 1.5 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 SDA1 PF05285.12 KND89646.1 - 1.8 7.9 14.1 2.9 7.2 14.1 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KND89646.1 - 2.3 7.7 11.4 3.8 7.0 11.4 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 KND89646.1 - 2.9 6.0 19.9 4.5 5.4 19.9 1.2 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 KND89646.1 - 3.1 8.1 13.4 6.5 7.1 13.4 1.4 1 0 0 1 1 1 0 Tubby N-terminal CDC45 PF02724.14 KND89646.1 - 8.8 4.5 12.0 13 3.9 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein IlvN PF07991.12 KND89647.1 - 3.1e-45 153.7 0.0 8.9e-45 152.2 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KND89647.1 - 1.8e-38 132.0 0.0 3.3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain WD40 PF00400.32 KND89647.1 - 1.4e-31 108.0 20.8 0.00021 22.0 0.1 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND89647.1 - 3.7e-15 56.0 7.2 5.7e-05 23.3 0.1 5.6 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND89647.1 - 1.6e-05 24.4 0.0 0.00025 20.5 0.0 2.2 1 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KND89647.1 - 0.0007 18.6 0.8 0.1 11.6 0.1 3.5 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND89647.1 - 0.0014 18.6 1.4 0.13 12.1 0.1 3.3 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KND89647.1 - 0.008 16.1 3.3 28 4.8 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 KND89647.1 - 0.041 12.9 0.2 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Coatomer WD associated region F420_oxidored PF03807.17 KND89647.1 - 0.065 13.8 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.16 KND89648.1 - 4.3e-18 65.8 0.0 2.9e-17 63.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 KND89649.1 - 1.3e-45 154.9 0.3 2.7e-45 153.9 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein ECR1_N PF14382.6 KND89650.1 - 1.7e-07 30.9 0.3 0.012 15.4 0.1 2.6 2 0 0 2 2 2 2 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KND89650.1 - 8.2e-06 26.1 0.2 1.9e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 KH domain HEPN_Toprim_N PF18871.1 KND89650.1 - 0.03 14.3 0.2 0.067 13.1 0.1 1.6 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 EXOSC1 PF10447.9 KND89650.1 - 0.065 13.9 0.8 1.5 9.5 0.1 2.7 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 Adap_comp_sub PF00928.21 KND89653.1 - 2.1e-67 227.3 0.0 2.7e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND89653.1 - 0.006 16.5 0.0 0.0095 15.9 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.21 KND89654.1 - 2.4e-21 76.6 0.2 4.5e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 Acyl transferase domain BTB PF00651.31 KND89658.1 - 3.7e-05 23.9 0.0 9.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Trypan_PARP PF05887.11 KND89658.1 - 0.1 12.6 17.8 0.17 11.9 17.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pheromone PF08015.11 KND89658.1 - 0.84 10.7 4.6 0.25 12.4 0.8 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone NAD_binding_10 PF13460.6 KND89659.1 - 2.7e-08 33.9 0.0 3.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KND89659.1 - 0.00087 18.5 0.0 0.0035 16.5 0.0 1.9 1 1 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 KND89659.1 - 0.066 12.7 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND89659.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 KND89659.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CTP_transf_1 PF01148.20 KND89660.1 - 1.3e-77 261.1 24.8 1.8e-77 260.7 24.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Methyltransf_23 PF13489.6 KND89660.1 - 7.5e-21 74.7 0.0 1.5e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89660.1 - 6.1e-09 36.5 0.0 1.9e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND89660.1 - 5.2e-07 30.2 0.0 3.5e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89660.1 - 1.4e-05 25.8 0.0 6.6e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89660.1 - 2.1e-05 24.4 0.0 0.00023 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KND89660.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DUF3636 PF12331.8 KND89661.1 - 2.7e-41 140.9 1.9 5.9e-41 139.8 1.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Nup54 PF13874.6 KND89661.1 - 0.0059 16.7 2.2 0.0059 16.7 2.2 2.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF2722 PF10846.8 KND89661.1 - 0.0077 15.2 15.6 0.012 14.6 15.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SPX PF03105.19 KND89661.1 - 0.092 12.6 15.7 0.16 11.9 15.7 1.3 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 KND89661.1 - 0.12 12.0 10.7 1.5 8.3 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) UPF0560 PF10577.9 KND89661.1 - 5.1 5.5 13.9 10 4.4 13.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Glycos_transf_1 PF00534.20 KND89662.1 - 1.3e-34 119.2 0.0 1.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KND89662.1 - 1.3e-27 96.8 0.0 2.2e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KND89662.1 - 2.1e-14 54.2 0.0 5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KND89662.1 - 9.8e-12 45.2 0.0 6e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KND89662.1 - 1.6e-09 38.0 0.0 4.6e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF485 PF04341.12 KND89662.1 - 0.019 14.9 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF1289 PF06945.13 KND89662.1 - 0.32 10.9 1.0 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Lysis_col PF02402.16 KND89663.1 - 0.2 11.3 2.3 0.22 11.2 0.5 1.9 2 0 0 2 2 2 0 Lysis protein UDPG_MGDP_dh_N PF03721.14 KND89665.1 - 1.6e-49 168.1 0.0 2.2e-31 108.9 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 KND89665.1 - 9.2e-29 99.5 0.1 1.9e-28 98.5 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 KND89665.1 - 1e-21 77.3 0.0 1.5e-16 60.7 0.0 3.2 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 KND89665.1 - 0.0094 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 KND89665.1 - 0.0094 15.9 0.0 2.9 7.9 0.0 3.2 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 KND89665.1 - 0.012 15.8 0.0 0.59 10.3 0.0 2.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KND89665.1 - 0.049 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KND89666.1 - 4.8e-09 36.4 0.0 7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KND89666.1 - 0.014 14.5 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 KND89666.1 - 0.014 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KND89666.1 - 0.053 13.6 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KND89666.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 KND89666.1 - 0.15 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MFS_1 PF07690.16 KND89667.1 - 9.3e-22 77.4 34.5 9.3e-22 77.4 34.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89667.1 - 0.0035 16.2 6.0 0.0035 16.2 6.0 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3397 PF11877.8 KND89667.1 - 3.5 7.9 7.2 0.28 11.4 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) CDH-cyt PF16010.5 KND89668.1 - 2.2e-18 66.6 0.0 3.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 KND89668.1 - 2.2e-06 27.9 11.5 2.2e-06 27.9 11.5 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KND89668.1 - 5e-05 23.0 4.8 6.7e-05 22.6 3.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.20 KND89668.1 - 0.026 14.1 9.1 0.63 9.6 9.1 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 XK-related PF09815.9 KND89668.1 - 0.031 13.3 0.3 0.031 13.3 0.3 1.5 2 0 0 2 2 2 0 XK-related protein DUF4079 PF13301.6 KND89668.1 - 0.034 14.3 12.7 18 5.5 12.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) RseC_MucC PF04246.12 KND89668.1 - 0.14 12.1 8.3 0.32 10.9 0.7 2.6 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Frag1 PF10277.9 KND89668.1 - 0.61 9.6 8.5 1.5 8.3 8.6 1.5 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF2157 PF09925.9 KND89668.1 - 0.79 9.5 14.8 3.8 7.3 1.9 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Caps_synth_CapC PF14102.6 KND89668.1 - 5.4 7.5 9.7 9.7 6.7 0.2 2.3 2 0 0 2 2 2 0 Capsule biosynthesis CapC DnaJ PF00226.31 KND89670.1 - 6.2e-11 42.3 0.3 9.6e-11 41.7 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L44 PF00935.19 KND89671.1 - 4.4e-37 126.4 12.5 6.6e-37 125.8 12.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ureidogly_lyase PF04115.12 KND89674.1 - 1.3e-50 171.8 0.0 1.8e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase MFS_1 PF07690.16 KND89675.1 - 1.4e-33 116.3 57.9 3.1e-29 102.0 36.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89675.1 - 5.6e-18 65.0 21.1 2.5e-14 53.0 7.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter HTH_36 PF13730.6 KND89675.1 - 0.1 12.5 0.1 0.75 9.8 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PC4 PF02229.16 KND89676.1 - 7.1e-24 83.2 0.3 1.5e-23 82.2 0.3 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.6 KND89676.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.0 2 0 0 2 2 2 0 YqfQ-like protein DUF3275 PF11679.8 KND89676.1 - 0.34 10.9 2.3 0.5 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) TSGP1 PF07771.11 KND89676.1 - 2.4 8.3 6.3 2.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Tick salivary peptide group 1 Pex24p PF06398.11 KND89677.1 - 0.00017 20.7 4.1 0.00031 19.8 4.1 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ion_trans PF00520.31 KND89680.1 - 0.0013 18.1 11.8 0.0022 17.3 11.8 1.4 1 0 0 1 1 1 1 Ion transport protein K_trans PF02705.16 KND89681.1 - 1.1e-183 611.6 17.0 1.3e-183 611.4 17.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF3433 PF11915.8 KND89682.1 - 1.3e-38 131.3 24.8 1.8e-21 76.4 3.1 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) TRP PF06011.12 KND89683.1 - 4.1e-163 543.0 31.3 5e-163 542.8 31.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND89683.1 - 7.3e-41 139.8 0.2 1.2e-40 139.1 0.2 1.3 1 0 0 1 1 1 1 ML-like domain TPR_16 PF13432.6 KND89684.1 - 0.00051 20.6 0.1 0.76 10.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND89684.1 - 0.042 14.0 0.1 0.3 11.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND89684.1 - 0.13 13.0 0.0 0.62 10.8 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat LPD11 PF18824.1 KND89685.1 - 0.079 13.0 0.3 0.84 9.8 0.1 2.7 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 11 Amidohydro_2 PF04909.14 KND89687.1 - 2.5e-05 24.2 0.0 3.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 KND89687.1 - 0.046 13.0 0.1 0.09 12.1 0.1 1.5 1 1 0 1 1 1 0 Amidohydrolase family Rad52_Rad22 PF04098.15 KND89688.1 - 1.2e-59 200.7 0.0 1.6e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8 PF08559.10 KND89689.1 - 1.6e-75 253.8 0.0 2e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein RRM_1 PF00076.22 KND89690.1 - 7.9e-19 67.3 0.2 7e-12 45.0 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND89690.1 - 0.0046 17.1 0.1 0.15 12.2 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 KND89690.1 - 0.0054 16.7 1.3 0.015 15.4 0.2 2.3 1 1 2 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 KND89690.1 - 0.086 12.6 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain HAND PF09110.11 KND89690.1 - 0.99 10.2 4.8 0.38 11.5 0.9 2.2 2 1 0 2 2 2 0 HAND GREB1 PF15782.5 KND89693.1 - 0.32 8.1 0.2 0.41 7.7 0.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF3g PF12353.8 KND89694.1 - 4.8 7.6 26.7 0.34 11.3 5.6 4.2 3 1 1 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G Aerolysin PF01117.20 KND89695.1 - 0.34 10.1 0.0 0.45 9.7 0.0 1.1 1 0 0 1 1 1 0 Aerolysin toxin Methyltransf_3 PF01596.17 KND89696.1 - 8.1e-31 106.9 0.0 1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 KND89696.1 - 5e-11 42.8 0.0 6.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 KND89696.1 - 1e-10 42.5 0.0 2.8e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89696.1 - 1.7e-09 37.6 0.0 2.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89696.1 - 1.8e-07 31.8 0.0 2.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND89696.1 - 0.00028 21.5 0.0 0.00055 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89696.1 - 0.0069 17.1 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND89696.1 - 0.0099 15.7 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND89696.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF2783 PF10932.8 KND89696.1 - 0.012 15.3 0.1 0.023 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) Ubie_methyltran PF01209.18 KND89696.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SUR7 PF06687.12 KND89697.1 - 3.9e-07 29.9 0.0 4.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Acetyltransf_10 PF13673.7 KND89699.1 - 3.5e-08 33.4 0.0 6.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND89699.1 - 7e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND89699.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KND89699.1 - 3.5e-05 23.9 0.0 5.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND89699.1 - 0.0042 17.0 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND89699.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.25 KND89700.1 - 1.2e-26 93.6 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89700.1 - 3.1e-15 56.1 0.0 4.2e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND89700.1 - 4.3e-07 29.1 0.0 6.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 KND89701.1 - 1.2e-51 175.3 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CNF1 PF05785.12 KND89701.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Rho-activating domain of cytotoxic necrotizing factor NMO PF03060.15 KND89702.1 - 8.5e-20 71.4 0.7 1.6e-14 54.0 0.1 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase TGF_beta_GS PF08515.12 KND89702.1 - 0.019 14.4 0.4 0.042 13.3 0.4 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Aldo_ket_red PF00248.21 KND89703.1 - 1.6e-70 237.6 0.0 1.9e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 KND89703.1 - 0.087 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 FliG middle domain Fungal_trans PF04082.18 KND89704.1 - 2.2e-14 53.2 0.0 3.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89704.1 - 1.1e-07 31.8 9.2 2.3e-07 30.8 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 KND89705.1 - 3.3e-15 56.0 0.0 2e-06 27.9 0.0 5.2 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.6 KND89705.1 - 3.3e-12 46.3 0.0 4.8e-08 33.0 0.0 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KND89705.1 - 4.2e-08 32.8 0.0 0.065 12.9 0.0 3.9 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 KND89705.1 - 8.5e-07 28.8 0.0 0.064 13.5 0.0 4.6 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 KND89705.1 - 0.017 14.5 0.0 0.12 11.7 0.0 2.3 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP SANT_DAMP1_like PF16282.5 KND89706.1 - 2.7e-32 110.8 0.9 5.9e-32 109.7 0.9 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 SUIM_assoc PF16619.5 KND89706.1 - 0.018 15.1 3.3 0.018 15.1 3.3 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glutaredoxin2_C PF04399.13 KND89706.1 - 0.76 9.6 3.5 0.74 9.7 1.0 2.2 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Hexapep PF00132.24 KND89707.1 - 1.4e-12 46.8 18.7 1.3e-06 27.8 2.3 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KND89707.1 - 4.1e-11 42.4 18.1 3.8e-06 26.6 1.8 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KND89707.1 - 1.5e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase VSG_B PF13206.6 KND89707.1 - 0.56 9.4 4.2 0.78 8.9 4.2 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain cwf18 PF08315.12 KND89708.1 - 1.5e-45 155.2 6.3 1.5e-45 155.2 6.3 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 KND89709.1 - 7.8e-13 48.2 6.3 6.1e-10 38.9 1.9 2.6 2 0 0 2 2 2 2 Zinc knuckle CAML PF14963.6 KND89709.1 - 2.2 8.4 6.1 3.8 7.6 6.1 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand A_deaminase PF00962.22 KND89711.1 - 4.9e-24 85.3 0.0 2.8e-23 82.8 0.0 2.1 3 0 0 3 3 3 1 Adenosine/AMP deaminase NAD_binding_10 PF13460.6 KND89712.1 - 8.4e-07 29.1 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND89712.1 - 9.9e-07 28.6 0.0 2.2e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 KND89712.1 - 0.0038 17.3 0.1 0.0071 16.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KND89712.1 - 0.097 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KND89712.1 - 0.15 12.3 0.3 0.34 11.2 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain Hydantoinase_B PF02538.14 KND89713.1 - 7.4e-221 734.0 0.1 1e-220 733.6 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KND89713.1 - 4e-77 259.3 0.4 7.3e-77 258.5 0.4 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Peptidase_C58 PF03543.14 KND89713.1 - 2.3 7.9 5.1 1.1 9.0 0.1 2.4 3 0 0 3 3 3 0 Yersinia/Haemophilus virulence surface antigen ADH_N PF08240.12 KND89714.1 - 3.9e-26 91.1 2.3 8.4e-26 90.0 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND89714.1 - 2.9e-20 72.6 0.6 5.7e-20 71.6 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND89714.1 - 0.006 16.1 0.2 0.016 14.7 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KND89714.1 - 0.022 14.0 1.1 0.04 13.2 1.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KND89714.1 - 0.032 13.8 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 KND89714.1 - 0.039 14.2 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HhH-GPD PF00730.25 KND89715.1 - 3.5e-17 62.8 0.0 8.4e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KND89715.1 - 4.1e-08 32.7 0.0 9.2e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Toxin_10 PF05431.11 KND89715.1 - 0.046 13.2 0.2 0.078 12.5 0.2 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 ApbE PF02424.15 KND89715.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 ApbE family Acyl-CoA_dh_1 PF00441.24 KND89718.1 - 3e-14 53.5 0.0 9.9e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KND89718.1 - 5.3e-12 45.8 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 KND89718.1 - 7.6e-12 45.4 0.0 2e-11 44.1 0.0 1.6 1 1 1 2 2 2 1 Adaptive response protein AidB N-terminal domain KSHV_K1 PF11049.8 KND89719.1 - 0.036 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus YpzI PF14140.6 KND89720.1 - 0.18 11.6 2.1 11 5.8 0.1 3.3 3 0 0 3 3 3 0 YpzI-like protein SPX PF03105.19 KND89723.1 - 1.3e-07 31.9 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 SPX domain COX1 PF00115.20 KND89723.1 - 0.016 14.1 2.2 0.021 13.7 2.2 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF4191 PF13829.6 KND89723.1 - 0.12 11.6 0.3 0.26 10.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Cytochrom_B_C PF00032.17 KND89723.1 - 0.39 11.0 1.7 1.1 9.6 0.1 2.1 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD FAM70 PF14967.6 KND89723.1 - 0.39 10.1 3.5 0.85 9.0 3.5 1.5 1 0 0 1 1 1 0 FAM70 protein Ceramidase_alk PF04734.13 KND89725.1 - 1.3e-211 703.6 0.0 1.5e-211 703.4 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KND89725.1 - 1.9e-54 184.0 0.1 3.3e-54 183.3 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal SIS PF01380.22 KND89726.1 - 3e-12 46.5 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KND89726.1 - 0.0076 16.3 0.0 0.026 14.6 0.0 1.8 1 1 1 2 2 2 1 SIS domain Tctex-1 PF03645.13 KND89727.1 - 2.7e-39 133.5 0.0 3.2e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 KND89729.1 - 1.5e-15 57.4 4.6 1.5e-15 57.4 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1430 PF07242.11 KND89729.1 - 0.056 13.7 2.3 2.9 8.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) SIT PF15330.6 KND89729.1 - 0.13 12.7 0.7 0.19 12.2 0.1 1.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Alba PF01918.21 KND89730.1 - 2.2e-05 24.2 0.0 3.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alba DUF1279 PF06916.13 KND89732.1 - 3.7e-26 91.5 0.1 5.7e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) FANCI_S4 PF14678.6 KND89732.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 Myb_DNA-binding PF00249.31 KND89733.1 - 2.1e-20 72.7 3.0 2.2e-10 40.6 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND89733.1 - 3.6e-16 59.1 1.5 2.7e-12 46.8 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_23 PF13384.6 KND89733.1 - 0.063 13.1 0.3 0.14 12.0 0.3 1.6 1 0 0 1 1 1 0 Homeodomain-like domain DUF2774 PF11242.8 KND89733.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) TFIIA PF03153.13 KND89734.1 - 0.063 13.3 4.8 0.066 13.2 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PNGaseA PF12222.8 KND89735.1 - 4.3e-140 467.4 0.0 5.5e-140 467.1 0.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF2950 PF11453.8 KND89735.1 - 0.062 12.5 0.8 0.1 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) MARVEL PF01284.23 KND89737.1 - 2.5e-26 92.4 19.0 2.9e-26 92.2 19.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain eIF-5_eIF-2B PF01873.17 KND89738.1 - 8.2e-42 141.8 0.7 1.5e-41 140.9 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KND89738.1 - 0.12 11.9 0.7 0.27 10.8 0.7 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.12 KND89738.1 - 0.96 9.3 3.9 5.5 6.9 4.2 2.1 1 1 1 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KND89738.1 - 1.5 9.2 8.1 1.4 9.3 0.4 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain Nucleoporin_C PF03177.14 KND89739.1 - 2.9e-162 541.5 4.1 3.8e-162 541.1 4.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KND89739.1 - 8.4e-84 281.8 0.0 1.2e-83 281.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Sedlin_N PF04628.13 KND89740.1 - 2.3e-10 40.7 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_M1 PF01433.20 KND89741.1 - 1e-42 146.2 0.2 1.6e-42 145.6 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KND89741.1 - 4.2e-36 123.5 0.0 7.5e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KND89741.1 - 5.2e-29 101.8 0.1 9.3e-29 100.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 KND89741.1 - 0.029 14.1 0.6 0.38 10.4 0.1 2.6 3 0 0 3 3 3 0 Peptidase MA superfamily Ten1 PF12658.7 KND89743.1 - 3.8e-29 101.1 0.0 4.2e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KND89743.1 - 2.9e-06 27.0 0.0 3.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF952 PF06108.12 KND89744.1 - 1.7e-22 79.2 0.0 2.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Uds1 PF15456.6 KND89745.1 - 4.6e-34 117.4 4.8 4.6e-34 117.4 4.8 1.9 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 KND89745.1 - 0.24 11.4 4.2 0.13 12.2 0.7 2.3 2 0 0 2 2 2 0 Stathmin family PXA PF02194.15 KND89746.1 - 1.5e-31 109.7 0.0 2.9e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KND89746.1 - 5.9e-21 75.1 0.0 1.8e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KND89746.1 - 7.8e-06 25.9 0.0 2.6e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 PX domain FAM76 PF16046.5 KND89746.1 - 6.7 6.0 5.5 0.54 9.6 0.5 1.6 2 0 0 2 2 2 0 FAM76 protein LAMTOR5 PF16672.5 KND89748.1 - 0.069 13.1 0.3 8.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Ragulator complex protein LAMTOR5 Kinesin PF00225.23 KND89749.1 - 1.5e-110 369.3 0.0 1.5e-110 369.3 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KND89749.1 - 7.9e-48 163.0 0.3 3e-47 161.1 0.0 2.2 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KND89749.1 - 2.4e-36 125.6 17.2 6.6e-32 111.1 0.2 3.9 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 KND89749.1 - 4.9e-24 85.0 0.5 1.3e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding KIF1B PF12423.8 KND89749.1 - 5e-07 30.0 0.2 2.5e-06 27.8 0.2 2.3 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 KND89749.1 - 0.0093 16.5 0.0 0.24 11.9 0.0 2.7 1 1 0 1 1 1 1 PH domain Yop-YscD_cpl PF16697.5 KND89749.1 - 0.059 13.7 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Styelin PF17562.2 KND89749.1 - 2.8 8.4 5.0 1.9 8.9 0.1 2.6 2 0 0 2 2 2 0 Styelin Med1 PF10744.9 KND89751.1 - 1.4e-119 399.9 0.0 1.7e-119 399.6 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Formyl_trans_N PF00551.19 KND89753.1 - 7.7e-20 71.4 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KND89753.1 - 0.00066 19.9 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Glyco_hydro_16 PF00722.21 KND89754.1 - 2.2e-08 33.8 0.1 2.2e-08 33.8 0.1 2.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Apt1 PF10351.9 KND89754.1 - 5.3 5.8 24.3 0.058 12.2 11.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain LIM PF00412.22 KND89755.1 - 3.7e-21 75.1 15.7 6.8e-11 42.2 3.7 2.9 3 0 0 3 3 3 2 LIM domain WRC PF08879.10 KND89755.1 - 0.024 14.4 0.5 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 WRC zf_UBZ PF18439.1 KND89755.1 - 1.1 8.9 7.6 3.4 7.4 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF3405 PF11885.8 KND89756.1 - 2.1e-191 637.1 11.9 2.9e-191 636.6 11.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) ERK-JNK_inhib PF15002.6 KND89756.1 - 0.027 14.2 4.4 0.061 13.0 4.4 1.5 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor RR_TM4-6 PF06459.12 KND89756.1 - 1.6 8.5 6.2 2.8 7.7 6.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran PF00156.27 KND89757.1 - 0.00027 20.5 0.0 0.00043 19.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_5 PF07994.12 KND89758.1 - 4.6e-147 489.6 0.3 5.8e-147 489.2 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KND89758.1 - 3.4e-32 110.9 2.3 1.6e-30 105.5 1.1 3.1 2 2 0 2 2 2 1 Myo-inositol-1-phosphate synthase MRC1 PF09444.10 KND89759.1 - 2e-41 141.9 17.5 2e-41 141.9 17.5 7.9 8 1 1 9 9 9 1 MRC1-like domain Plk4_PB2 PF18409.1 KND89759.1 - 0.14 12.9 2.6 0.23 12.2 0.2 2.5 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 3HCDH_RFF PF18321.1 KND89759.1 - 0.33 11.4 2.2 5.1 7.6 0.1 3.0 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Nse4_C PF08743.10 KND89761.1 - 1.1e-34 118.5 0.0 2.9e-34 117.2 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KND89761.1 - 2.5e-19 69.1 1.6 9.1e-19 67.3 0.0 2.9 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE bMG6 PF17962.1 KND89762.1 - 0.047 13.8 0.9 0.09 12.9 0.9 1.4 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 PI3Ka PF00613.20 KND89763.1 - 9.2e-58 194.7 0.4 1.5e-57 194.0 0.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KND89763.1 - 1.1e-45 156.4 0.1 3e-31 109.1 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KND89763.1 - 5.4e-32 110.6 0.0 9.1e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4336 PF14234.6 KND89764.1 - 1.3e-10 41.0 0.0 1.6e-06 27.6 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) ADH_zinc_N PF00107.26 KND89766.1 - 6.2e-14 52.1 0.1 1e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND89766.1 - 0.085 12.8 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MMR_HSR1 PF01926.23 KND89767.1 - 5e-13 49.1 0.0 8.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND89767.1 - 1.4e-06 28.4 0.1 3.3e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KND89767.1 - 0.0022 17.6 0.3 0.0063 16.1 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KND89767.1 - 0.0086 16.5 0.2 0.015 15.7 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KND89767.1 - 0.01 15.9 0.1 0.73 9.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 KND89767.1 - 0.012 15.9 0.6 8.1 6.7 0.0 3.1 2 1 1 3 3 3 0 AAA domain Septin PF00735.18 KND89767.1 - 0.034 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 KND89767.1 - 0.047 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family MCM PF00493.23 KND89767.1 - 0.052 12.6 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 KND89767.1 - 0.056 13.2 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KND89767.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KND89767.1 - 0.1 13.1 1.0 0.19 12.3 0.3 1.8 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 KND89767.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein HCO3_cotransp PF00955.21 KND89768.1 - 2.3e-60 204.9 11.0 6.8e-30 104.4 0.5 2.8 1 1 1 2 2 2 2 HCO3- transporter family ATP-synt_C PF00137.21 KND89769.1 - 5.8e-27 93.8 34.1 1.1e-16 61.0 12.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 KND89769.1 - 0.2 11.0 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 CNH PF00780.22 KND89770.1 - 2.1e-79 267.0 0.0 7.8e-79 265.1 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 KND89770.1 - 1.7e-42 144.7 0.0 4.5e-42 143.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KND89770.1 - 1e-32 113.8 0.0 2e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KND89770.1 - 2.8e-15 56.1 0.1 5.6e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GPI2 PF06432.11 KND89771.1 - 9e-130 432.1 0.1 1.1e-129 431.9 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 2-Hacid_dh_C PF02826.19 KND89773.1 - 1.3e-38 132.1 0.0 7.5e-29 100.3 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 KND89773.1 - 0.007 16.9 0.0 0.017 15.6 0.0 1.6 1 1 0 1 1 1 1 XdhC Rossmann domain ApbA PF02558.16 KND89773.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.32 KND89774.1 - 3.7e-08 33.9 12.2 0.00042 21.1 0.2 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KND89774.1 - 1.7e-06 27.5 10.6 3.6e-06 26.5 10.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 KND89774.1 - 0.00096 19.4 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KND89774.1 - 0.045 14.1 6.4 0.099 13.0 6.4 1.6 1 0 0 1 1 1 0 Ring finger domain zinc_ribbon_16 PF17034.5 KND89774.1 - 0.4 10.9 5.1 0.83 9.9 5.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family UQ_con PF00179.26 KND89775.1 - 1.2e-47 161.1 0.0 1.4e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND89775.1 - 0.00042 20.0 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KND89775.1 - 0.0055 16.6 0.1 0.01 15.7 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KND89775.1 - 0.073 13.4 0.1 0.092 13.0 0.1 1.4 1 1 0 1 1 1 0 RWD domain Mt_ATP-synt_D PF05873.12 KND89776.1 - 2.9e-19 69.4 3.5 3.6e-19 69.1 3.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TPR_MLP1_2 PF07926.12 KND89776.1 - 0.29 11.2 10.2 1.2 9.2 1.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 KND89776.1 - 1.2 9.7 7.0 0.59 10.7 0.5 2.2 1 1 1 2 2 2 0 Spectrin repeat Ribosomal_L14e PF01929.17 KND89777.1 - 7.8e-31 106.4 3.9 1e-30 106.0 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 BBP7 PF07585.11 KND89778.1 - 0.049 12.8 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative beta barrel porin-7 (BBP7) Rhomboid_SP PF12595.8 KND89779.1 - 0.0048 16.3 0.1 0.0068 15.8 0.1 1.2 1 0 0 1 1 1 1 Rhomboid serine protease NAC PF01849.18 KND89780.1 - 4.1e-24 84.3 0.2 1.4e-23 82.6 0.0 2.0 2 0 0 2 2 2 1 NAC domain Cwf_Cwc_15 PF04889.12 KND89780.1 - 0.81 9.4 17.0 2 8.1 6.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PGA2 PF07543.12 KND89780.1 - 1.4 8.9 13.1 5.5 7.0 0.8 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 MRI PF15325.6 KND89780.1 - 2 9.5 10.3 0.29 12.2 2.6 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection Rad21_Rec8_N PF04825.13 KND89781.1 - 3.4e-32 110.9 0.0 5.9e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KND89781.1 - 0.00026 20.2 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 KND89781.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Asp PF00026.23 KND89782.1 - 3.2e-53 181.2 2.1 2.2e-52 178.4 2.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND89782.1 - 4.4e-10 40.1 1.2 5e-08 33.4 1.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND89782.1 - 0.00045 20.8 0.3 0.16 12.7 0.0 3.6 3 1 1 4 4 4 1 Aspartyl protease gag-asp_proteas PF13975.6 KND89782.1 - 0.084 13.4 0.1 9 6.9 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KND89782.1 - 0.15 11.8 0.0 0.78 9.5 0.0 2.2 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal G-patch PF01585.23 KND89783.1 - 2.1e-10 40.3 3.7 4.7e-10 39.2 3.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KND89783.1 - 8.9e-06 25.7 3.7 2.6e-05 24.2 3.7 1.8 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KND89783.1 - 1.9e-05 23.9 3.3 4.1e-05 22.8 3.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.13 KND89783.1 - 0.019 14.6 4.3 0.037 13.6 4.3 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 KND89783.1 - 0.025 14.9 0.1 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 KND89783.1 - 0.031 14.1 0.3 13 5.7 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 KND89783.1 - 0.71 9.2 5.2 1.4 8.2 5.2 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Oxysterol_BP PF01237.18 KND89784.1 - 1.1e-134 449.0 0.1 2e-133 444.9 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 KND89784.1 - 1.3e-16 60.4 0.1 3.6e-10 39.9 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KND89784.1 - 1e-15 57.3 0.2 1.3e-05 25.4 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KND89784.1 - 6.4e-14 52.3 0.0 4.8e-09 36.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND89784.1 - 1.1e-12 46.9 0.0 0.00022 21.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KND89784.1 - 6.4e-12 45.7 0.0 5.7e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KND89784.1 - 2.7e-11 43.9 1.1 5.3e-11 43.0 1.1 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KND89784.1 - 6.9e-08 32.7 1.1 1.8e-07 31.3 1.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.6 KND89785.1 - 9.8e-82 274.9 0.8 1.2e-81 274.7 0.8 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KND89785.1 - 5.6e-22 78.0 0.0 1.6e-11 44.2 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Ge1_WD40 PF16529.5 KND89785.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ferric_reduct PF01794.19 KND89786.1 - 5.5e-19 68.5 4.6 5.5e-19 68.5 4.6 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND89786.1 - 6.2e-14 52.4 0.0 1.1e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KND89786.1 - 1.3e-11 44.6 0.1 5.1e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KND89786.1 - 3.3e-05 24.5 0.0 0.13 12.9 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain AIM3 PF17096.5 KND89786.1 - 0.12 13.3 0.6 0.32 11.9 0.6 1.6 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF4405 PF14358.6 KND89786.1 - 0.15 12.6 8.2 0.089 13.4 1.6 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RNase_PH PF01138.21 KND89787.1 - 7.4e-18 65.3 0.0 1.3e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND89787.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MoaE PF02391.17 KND89788.1 - 7.2e-37 126.1 0.0 8.9e-37 125.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Lipase_GDSL_lke PF16255.5 KND89788.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.22 KND89790.1 - 1.1e-13 50.8 0.0 1.7e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.22 KND89791.1 - 1.5e-38 131.9 0.0 2.6e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_76 PF03663.14 KND89792.1 - 9.3e-160 532.1 19.8 1.3e-159 531.7 19.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND89792.1 - 0.67 9.0 12.6 2.5 7.1 1.9 3.3 1 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.21 KND89793.1 - 2.8e-32 110.3 1.4 3.2e-32 110.2 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 KND89793.1 - 0.12 13.1 0.1 0.35 11.6 0.0 1.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor NAT PF04768.13 KND89794.1 - 2.5e-45 154.2 0.0 4.5e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KND89794.1 - 2.5e-31 109.2 0.1 1.1e-30 107.0 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KND89794.1 - 3.7e-28 98.4 0.0 9e-28 97.1 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 KND89795.1 - 1.3e-23 83.5 0.0 1.3e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Med17 PF10156.9 KND89796.1 - 6.1e-88 295.5 0.0 8.3e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Lumazine_bd_2 PF12893.7 KND89796.1 - 0.18 12.5 0.1 0.4 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative lumazine-binding SNF2_N PF00176.23 KND89797.1 - 9e-55 185.8 0.0 1.9e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND89797.1 - 6.1e-16 58.7 0.1 1.9e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KND89797.1 - 1e-08 34.9 1.8 2.1e-08 33.9 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND89797.1 - 2.9e-08 33.5 3.7 6.2e-08 32.4 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND89797.1 - 1.5e-07 31.1 1.9 1.5e-07 31.1 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND89797.1 - 7.6e-07 29.1 1.0 7.6e-07 29.1 1.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND89797.1 - 2.1e-06 27.6 3.7 4.7e-06 26.5 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND89797.1 - 5.4e-06 26.6 4.4 1.2e-05 25.5 4.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KND89797.1 - 0.00029 20.9 4.5 0.00089 19.4 4.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KND89797.1 - 0.0085 15.9 3.0 0.038 13.8 3.2 2.0 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain ERCC3_RAD25_C PF16203.5 KND89797.1 - 0.0088 15.3 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SPT6_acidic PF14632.6 KND89797.1 - 0.012 16.1 6.3 0.035 14.7 6.3 1.8 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Baculo_IE-1 PF05290.11 KND89797.1 - 0.092 12.7 3.1 0.089 12.7 1.4 1.8 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) zf-MIZ PF02891.20 KND89797.1 - 0.48 10.2 3.9 1.4 8.7 3.9 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 KND89797.1 - 0.51 10.2 10.9 9.6 6.2 11.3 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Phosphodiest PF01663.22 KND89798.1 - 9.5e-96 321.5 0.7 1.3e-95 321.1 0.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND89798.1 - 0.00045 19.7 0.0 0.048 13.1 0.0 2.3 1 1 1 2 2 2 2 Sulfatase TPR_16 PF13432.6 KND89799.1 - 0.34 11.6 8.8 1.2 9.9 1.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Myosin_head PF00063.21 KND89801.1 - 1e-266 886.6 0.0 2.3e-266 885.4 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 KND89801.1 - 3.7e-12 45.9 0.3 8e-12 44.8 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF724 PF05266.14 KND89801.1 - 7.1e-05 22.7 13.1 7.1e-05 22.7 13.1 15.3 4 2 13 18 18 18 2 Protein of unknown function (DUF724) Filament PF00038.21 KND89801.1 - 0.0023 17.6 13.4 0.0023 17.6 13.4 10.9 3 2 5 8 8 8 3 Intermediate filament protein Myosin_tail_1 PF01576.19 KND89801.1 - 0.0071 14.2 274.6 0.037 11.8 162.5 6.1 1 1 1 2 2 2 1 Myosin tail AAA_22 PF13401.6 KND89801.1 - 0.043 14.1 0.0 0.043 14.1 0.0 5.0 5 0 0 5 5 5 0 AAA domain 53-BP1_Tudor PF09038.10 KND89801.1 - 0.071 13.1 0.5 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor AAA_7 PF12775.7 KND89801.1 - 0.7 9.4 3.1 0.41 10.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region CNH PF00780.22 KND89802.1 - 4.6e-62 210.1 0.0 7.5e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KND89802.1 - 6.1e-35 121.1 0.3 9.4e-35 120.5 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KND89802.1 - 2e-11 44.1 0.0 7.9e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KND89802.1 - 0.00026 21.5 0.0 0.043 14.3 0.0 3.5 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 KND89802.1 - 0.011 15.6 0.0 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 PH domain Tropomyosin PF00261.20 KND89802.1 - 0.24 10.7 1.5 0.47 9.8 1.5 1.4 1 0 0 1 1 1 0 Tropomyosin HgmA PF04209.13 KND89803.1 - 3.1e-142 474.2 0.2 3.5e-142 474.1 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ribosomal_L25p PF01386.19 KND89804.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L25p family MPC PF03650.13 KND89805.1 - 9.1e-36 122.4 3.2 6.8e-22 77.7 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial pyruvate carriers SOCS_box PF07525.16 KND89805.1 - 0.24 11.8 1.2 0.6 10.5 1.2 1.6 1 0 0 1 1 1 0 SOCS box FA_desaturase PF00487.24 KND89806.1 - 2.1e-16 60.6 25.5 2.6e-16 60.2 24.5 1.6 1 1 1 2 2 2 1 Fatty acid desaturase RseC_MucC PF04246.12 KND89806.1 - 0.02 14.8 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC EMC3_TMCO1 PF01956.16 KND89806.1 - 0.05 13.3 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like 60KD_IMP PF02096.20 KND89806.1 - 0.1 12.5 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 60Kd inner membrane protein DUF1687 PF07955.11 KND89807.1 - 1.9e-30 105.9 0.1 3.1e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) HupH_C PF04809.13 KND89807.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Rotamase PF00639.21 KND89807.1 - 0.13 13.3 1.0 1.2 10.2 0.1 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain zf-C3H1 PF10650.9 KND89808.1 - 8.1e-06 25.5 2.5 1.4e-05 24.7 2.5 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain RTA1 PF04479.13 KND89809.1 - 5.6e-73 245.0 3.8 9.4e-73 244.2 3.8 1.3 1 0 0 1 1 1 1 RTA1 like protein SUR7 PF06687.12 KND89810.1 - 2.3e-32 112.3 7.6 3e-32 112.0 7.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.14 KND89810.1 - 0.93 9.9 6.1 0.28 11.6 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) BPL_LplA_LipB PF03099.19 KND89811.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3_PI4_kinase PF00454.27 KND89812.1 - 5.4e-49 167.3 0.0 8.7e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KND89812.1 - 2.6e-34 119.0 1.5 2.6e-34 119.0 1.5 1.7 2 0 0 2 2 2 1 FAT domain UME PF08064.13 KND89812.1 - 1e-32 112.1 0.1 6.3e-32 109.5 0.1 2.6 1 0 0 1 1 1 1 UME (NUC010) domain zf-PARP PF00645.18 KND89812.1 - 1.3e-20 74.0 0.8 1.3e-20 74.0 0.8 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FATC PF02260.20 KND89812.1 - 6.6e-13 48.2 0.0 1.8e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 FATC domain HSP70 PF00012.20 KND89812.1 - 1.7e-11 43.0 0.0 1.7e-11 43.0 0.0 2.4 3 0 0 3 3 3 1 Hsp70 protein TPR_19 PF14559.6 KND89812.1 - 0.014 15.9 3.5 0.019 15.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND89812.1 - 3.6 8.7 7.1 31 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 KND89813.1 - 2.6 7.5 6.0 3.9 7.0 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit WDCP PF15390.6 KND89813.1 - 4.3 5.6 6.5 6 5.1 6.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family UPF0242 PF06785.11 KND89813.1 - 5.3 7.1 14.0 8.3 6.5 14.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GGACT PF06094.12 KND89814.1 - 4.4e-10 40.2 0.0 6.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KND89814.1 - 5.3e-06 26.7 0.1 0.0013 19.0 0.0 2.6 2 0 0 2 2 2 2 AIG2-like family DUF2790 PF10976.8 KND89814.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Amidoligase_2 PF12224.8 KND89815.1 - 7.4e-13 48.7 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme HemY_N PF07219.13 KND89815.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus CPSase_L_D2 PF02786.17 KND89816.1 - 4.3e-74 248.6 0.0 6.9e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KND89816.1 - 3.4e-35 120.4 0.0 7.3e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KND89816.1 - 7.6e-35 119.8 0.0 1.7e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KND89816.1 - 1.7e-15 56.6 2.6 7.3e-15 54.6 2.6 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KND89816.1 - 7.9e-08 32.0 0.2 0.0056 16.5 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KND89816.1 - 4.3e-07 29.7 0.0 9.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KND89816.1 - 1.5e-06 27.9 0.0 3.9e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 KND89816.1 - 0.00042 21.0 0.1 0.33 11.7 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 KND89816.1 - 0.0035 16.6 0.0 2 7.6 0.0 2.8 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KND89816.1 - 0.0047 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 KND89816.1 - 0.061 13.5 0.0 0.22 11.7 0.0 2.0 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 GCV_H PF01597.19 KND89816.1 - 0.2 11.5 0.7 0.49 10.3 0.2 1.9 2 0 0 2 2 2 0 Glycine cleavage H-protein Putative_PNPOx PF01243.20 KND89817.1 - 4.2e-12 46.1 0.0 6.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KND89817.1 - 0.051 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 KND89817.1 - 0.056 11.9 0.1 0.066 11.6 0.1 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Mem_trans PF03547.18 KND89818.1 - 2e-45 154.9 0.0 2.6e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 KND89819.1 - 1e-55 188.9 0.0 1.4e-52 178.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND89819.1 - 1.4e-30 106.5 0.0 2.6e-29 102.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND89819.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KND89819.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KND89819.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Glyco_hydro_35 PF01301.19 KND89821.1 - 1.3e-84 284.5 0.0 2e-84 283.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KND89821.1 - 4.9e-57 192.6 0.0 8.4e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 KND89821.1 - 2.5e-52 176.3 0.3 8.8e-25 87.5 0.0 2.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KND89821.1 - 8.1e-24 83.0 0.1 1.6e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Dabb PF07876.12 KND89823.1 - 3.6e-11 43.5 0.1 4.5e-11 43.2 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain YIF1 PF03878.15 KND89824.1 - 3.9e-87 291.7 3.7 3.7e-77 259.1 1.1 2.0 1 1 1 2 2 2 2 YIF1 Yip1 PF04893.17 KND89824.1 - 0.19 11.4 6.5 0.57 9.9 6.5 1.8 1 1 0 1 1 1 0 Yip1 domain PAM2 PF07145.15 KND89826.1 - 0.0019 17.8 5.8 0.25 11.1 1.0 3.7 3 0 0 3 3 3 2 Ataxin-2 C-terminal region XkdW PF09636.10 KND89826.1 - 5 7.3 8.5 0.68 10.0 0.6 3.2 2 0 0 2 2 2 0 XkdW protein SRP-alpha_N PF04086.13 KND89828.1 - 7.1e-83 278.9 0.1 9.6e-83 278.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KND89828.1 - 2.7e-53 180.5 0.3 4.5e-53 179.8 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 KND89828.1 - 6.9e-06 25.2 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 KND89828.1 - 4.4e-05 23.6 0.4 0.00013 22.2 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 KND89828.1 - 0.00035 20.4 0.2 0.00083 19.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KND89828.1 - 0.0016 18.9 0.6 0.0039 17.6 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 KND89828.1 - 0.0073 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 KND89828.1 - 0.011 15.8 0.4 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KND89828.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KND89828.1 - 0.018 14.6 0.2 0.036 13.6 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KND89828.1 - 0.026 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KND89828.1 - 0.027 14.5 0.8 0.16 12.1 0.8 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KND89828.1 - 0.035 14.5 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KND89828.1 - 0.036 14.6 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND89828.1 - 0.037 13.3 0.1 0.15 11.3 0.1 2.0 1 1 0 1 1 1 0 Zeta toxin AAA_31 PF13614.6 KND89828.1 - 0.053 13.4 0.2 1.3 8.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KND89828.1 - 0.086 13.4 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DTHCT PF08070.11 KND89828.1 - 0.11 13.3 4.6 0.24 12.2 4.6 1.5 1 0 0 1 1 1 0 DTHCT (NUC029) region Med3 PF11593.8 KND89828.1 - 0.21 10.7 2.7 0.34 10.1 2.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Amidohydro_3 PF07969.11 KND89830.1 - 2.9e-05 23.7 0.0 3.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KND89830.1 - 0.0086 15.4 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Mid2 PF04478.12 KND89831.1 - 7.1e-07 29.2 1.5 7.1e-07 29.2 1.5 2.3 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor Ycf9 PF01737.17 KND89831.1 - 0.034 14.0 0.4 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 YCF9 TPR_21 PF09976.9 KND89831.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain AA_permease PF00324.21 KND89832.1 - 1.1e-123 413.3 46.7 1.4e-123 413.1 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND89832.1 - 2.1e-29 102.6 50.4 2.7e-29 102.3 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 KND89832.1 - 0.26 11.8 0.8 3 8.4 0.1 2.4 2 0 0 2 2 2 0 Pet100 NCE101 PF11654.8 KND89832.1 - 0.51 10.1 3.4 0.24 11.2 0.7 1.9 2 0 0 2 2 2 0 Non-classical export protein 1 Acetyltransf_1 PF00583.25 KND89833.1 - 0.014 15.6 0.0 0.053 13.7 0.0 2.0 1 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KND89833.1 - 0.023 14.8 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Thioredoxin PF00085.20 KND89834.1 - 3.3e-26 91.3 0.0 4.7e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KND89834.1 - 5e-05 23.7 0.1 0.00012 22.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KND89834.1 - 0.00025 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KND89834.1 - 0.00054 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KND89834.1 - 0.0008 18.8 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KND89834.1 - 0.0085 15.8 0.1 0.014 15.1 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KND89834.1 - 0.014 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KND89834.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Methyltrn_RNA_3 PF02598.17 KND89835.1 - 1.3e-103 346.5 0.0 1.5e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase MFS_1 PF07690.16 KND89836.1 - 1.4e-48 165.7 36.5 1.4e-48 165.7 36.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89836.1 - 1.5e-17 63.6 0.5 1.5e-17 63.6 0.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KND89836.1 - 7.6e-07 27.8 5.2 7.6e-07 27.8 5.2 2.8 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KND89836.1 - 0.0035 15.8 12.4 0.0057 15.1 12.4 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector Pyr_redox_2 PF07992.14 KND89837.1 - 4.8e-35 121.2 0.0 6.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND89837.1 - 9e-14 51.8 0.0 1.2e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND89837.1 - 1.6e-08 34.2 0.0 4.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND89837.1 - 3.2e-08 33.1 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KND89837.1 - 0.052 12.6 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KND89837.1 - 0.075 13.3 0.0 20 5.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TP_methylase PF00590.20 KND89838.1 - 3.8e-46 157.7 0.8 6.5e-46 156.9 0.8 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 KND89838.1 - 4.9e-15 55.8 0.0 9.9e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KND89838.1 - 1.2e-10 40.9 0.3 1.4e-09 37.5 0.3 2.2 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KND89838.1 - 1.9e-10 40.0 0.1 4.6e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rsm22 PF09243.10 KND89839.1 - 2.5e-30 105.7 0.0 3e-29 102.1 0.0 2.8 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Zn_clus PF00172.18 KND89839.1 - 7.8e-08 32.3 7.9 1.5e-07 31.4 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND89839.1 - 2.1e-07 30.3 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FTZ PF03867.14 KND89839.1 - 0.021 14.4 3.4 0.059 12.9 3.4 1.7 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Methyltransf_12 PF08242.12 KND89839.1 - 0.24 12.1 1.2 0.43 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KND89840.1 - 3.3e-13 49.5 0.3 1.1e-12 47.8 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND89840.1 - 1.8e-09 37.5 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III_C PF08541.10 KND89840.1 - 0.11 12.6 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Lyase_1 PF00206.20 KND89841.1 - 4.6e-105 351.4 0.0 5.5e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Lyase Pal1 PF08316.11 KND89842.1 - 1e-48 165.6 2.7 1e-48 165.6 0.9 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein SPX PF03105.19 KND89843.1 - 0.018 15.0 1.7 0.027 14.4 1.7 1.3 1 0 0 1 1 1 0 SPX domain Mito_fiss_reg PF05308.11 KND89843.1 - 2.7 8.0 19.3 2.9 7.9 9.6 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 KND89844.1 - 4.3e-26 91.9 0.0 5.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89844.1 - 1.2e-13 51.0 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND89844.1 - 6.3e-09 35.1 0.0 9.2e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND89844.1 - 0.00028 20.9 0.0 0.0019 18.2 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 KND89845.1 - 1.7e-05 24.4 0.0 3e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CLPTM1 PF05602.12 KND89845.1 - 0.28 10.1 0.0 0.41 9.6 0.0 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) RabGAP-TBC PF00566.18 KND89846.1 - 9.6e-46 156.1 0.0 1.5e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 KND89846.1 - 0.00098 18.9 0.1 0.3 11.1 0.1 3.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KND89846.1 - 0.019 14.5 0.1 1.3 8.7 0.1 3.4 3 0 0 3 3 3 0 EF hand GRAM PF02893.20 KND89846.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 GRAM domain EF-hand_7 PF13499.6 KND89846.1 - 0.13 12.8 0.3 0.91 10.0 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain pair NUDIX PF00293.28 KND89847.1 - 2.3e-09 37.4 0.4 1.7e-08 34.6 0.4 2.0 1 1 0 1 1 1 1 NUDIX domain adh_short_C2 PF13561.6 KND89850.1 - 8.3e-53 179.3 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND89850.1 - 9.8e-37 126.3 0.1 1.6e-36 125.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND89850.1 - 4.5e-12 46.2 0.1 1.5e-11 44.5 0.1 1.7 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 KND89850.1 - 0.072 12.5 0.0 3.6 6.9 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acyl-CoA_dh_1 PF00441.24 KND89851.1 - 1.3e-39 135.8 1.1 1.3e-39 135.8 1.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND89851.1 - 2.6e-32 111.8 0.0 6.1e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND89851.1 - 6.3e-27 93.6 0.1 1.3e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND89851.1 - 1.8e-12 47.7 0.2 1.8e-12 47.7 0.2 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KND89851.1 - 0.00095 18.9 0.0 0.0024 17.6 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1752 PF08550.10 KND89853.1 - 0.00046 20.0 1.6 0.00094 19.0 1.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) KdpC PF02669.15 KND89853.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain rhaM PF05336.13 KND89854.1 - 1.4e-36 124.8 0.3 1.6e-36 124.6 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase QCR10 PF09796.9 KND89855.1 - 1.4 9.1 5.6 9.7 6.3 0.6 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Carboxyl_trans PF01039.22 KND89856.1 - 7.5e-137 456.9 0.3 9.8e-137 456.6 0.3 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KND89856.1 - 0.0052 16.3 0.5 0.66 9.4 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) DUF997 PF06196.12 KND89857.1 - 0.06 13.4 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF997) EGF PF00008.27 KND89857.1 - 0.18 12.1 4.6 0.34 11.3 4.6 1.4 1 0 0 1 1 1 0 EGF-like domain PHD PF00628.29 KND89858.1 - 3.9e-09 36.3 2.0 3.9e-09 36.3 2.0 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KND89858.1 - 0.014 15.0 2.4 0.022 14.3 2.4 1.4 1 0 0 1 1 1 0 PHD-finger CEBP_ZZ PF16366.5 KND89858.1 - 0.082 13.2 2.9 0.22 11.8 2.9 1.7 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-CW PF07496.15 KND89858.1 - 0.14 12.2 0.9 0.35 10.9 0.9 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger TIMELESS_C PF05029.13 KND89859.1 - 2.4 7.2 6.5 2 7.5 5.2 1.4 2 0 0 2 2 2 0 Timeless protein C terminal region TFIIA PF03153.13 KND89859.1 - 3 7.8 7.5 4.5 7.2 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIS_C PF01096.18 KND89860.1 - 1.7e-20 72.5 2.1 1.7e-20 72.5 2.1 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KND89860.1 - 0.069 13.0 3.1 0.31 10.9 0.1 2.7 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Ank_4 PF13637.6 KND89862.1 - 5.3e-05 23.7 0.0 0.56 10.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND89862.1 - 0.00018 21.7 0.1 0.36 11.2 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND89862.1 - 0.0002 21.9 0.0 0.043 14.4 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND89862.1 - 0.0041 17.5 1.9 19 6.2 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KND89862.1 - 0.0052 17.2 0.0 3.7 8.1 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat Thaumatin PF00314.17 KND89863.1 - 1.6e-67 227.3 8.9 2.1e-67 226.9 8.9 1.2 1 0 0 1 1 1 1 Thaumatin family HSP70 PF00012.20 KND89864.1 - 6.6e-11 41.1 0.2 1.5e-09 36.6 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KND89864.1 - 0.021 13.6 0.1 0.11 11.2 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein MFS_5 PF05631.14 KND89865.1 - 3.8e-63 213.5 7.1 5.3e-63 213.1 7.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KND89865.1 - 5.1e-14 52.0 24.5 2.5e-13 49.7 24.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KND89865.1 - 3.2 7.4 6.6 10 5.7 1.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Acetyltransf_1 PF00583.25 KND89866.1 - 0.00019 21.7 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Hexokinase_2 PF03727.16 KND89867.1 - 9.2e-77 257.7 0.0 3e-76 256.0 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 KND89867.1 - 1.4e-74 250.3 0.0 2.2e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF883 PF05957.13 KND89867.1 - 0.26 11.9 2.5 23 5.6 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) CFEM PF05730.11 KND89868.1 - 6.6e-10 38.9 12.5 1.2e-09 38.1 12.5 1.5 1 0 0 1 1 1 1 CFEM domain Metallophos PF00149.28 KND89869.1 - 2.1e-11 44.7 0.0 5.1e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND89869.1 - 7.1e-09 36.1 0.0 6.6e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aldolase_II PF00596.21 KND89869.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Sgf11 PF08209.11 KND89870.1 - 0.015 14.8 2.5 0.015 14.8 2.5 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF2732 PF10809.8 KND89870.1 - 0.021 14.7 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) zf_UBZ PF18439.1 KND89870.1 - 0.4 10.3 2.3 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DLH PF01738.18 KND89872.1 - 1.6e-13 50.7 0.1 2e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family PFK PF00365.20 KND89873.1 - 3.7e-188 623.7 0.2 2.1e-104 348.8 0.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KND89873.1 - 0.02 14.7 2.0 0.047 13.4 2.0 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif TgMIC1 PF11476.8 KND89873.1 - 0.16 11.7 1.4 4.7 7.0 0.1 3.0 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Glyco_hydro_16 PF00722.21 KND89874.1 - 1e-41 142.4 0.9 1.4e-41 141.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SAICAR_synt PF01259.18 KND89875.1 - 3.7e-99 331.4 0.0 4.2e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Aminotran_1_2 PF00155.21 KND89876.1 - 7.4e-47 160.3 0.0 8.7e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KND89876.1 - 0.0081 15.5 0.0 0.027 13.8 0.0 2.0 1 1 1 2 2 2 1 Beta-eliminating lyase Aminotran_3 PF00202.21 KND89876.1 - 0.034 12.8 0.0 0.069 11.8 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-III DUF865 PF05906.11 KND89876.1 - 0.11 12.3 0.6 3 7.7 0.0 2.6 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Fungal_trans PF04082.18 KND89877.1 - 2.8e-11 43.0 0.0 4.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89877.1 - 0.02 15.0 7.8 0.039 14.1 7.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.19 KND89879.1 - 8.9e-76 254.9 0.0 1.2e-75 254.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KND89879.1 - 4.4e-24 84.9 0.0 9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HEAT PF02985.22 KND89880.1 - 7.7e-14 50.6 14.4 0.024 14.9 0.0 9.2 10 0 0 10 10 8 4 HEAT repeat HEAT_EZ PF13513.6 KND89880.1 - 3.6e-10 40.1 13.6 4.8e-07 30.1 0.0 7.8 7 2 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 KND89880.1 - 1.1e-07 32.1 16.4 0.0054 17.1 0.3 7.0 4 2 3 7 7 7 3 HEAT repeats CLASP_N PF12348.8 KND89880.1 - 1.5e-06 27.9 1.8 0.07 12.7 0.0 5.0 5 1 1 6 6 6 2 CLASP N terminal IBN_N PF03810.19 KND89880.1 - 1.3e-05 25.0 12.4 2.1e-05 24.4 1.3 5.2 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND89880.1 - 6e-05 23.1 7.5 0.97 9.5 0.0 6.2 6 2 0 7 7 7 2 Exportin 1-like protein Cse1 PF08506.10 KND89880.1 - 0.0031 16.4 0.0 0.46 9.3 0.1 3.3 3 0 0 3 3 3 1 Cse1 DUF3385 PF11865.8 KND89880.1 - 0.0032 17.4 2.5 6.2 6.7 0.0 4.9 3 2 2 5 5 5 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 KND89880.1 - 0.0061 16.3 0.3 14 5.4 0.7 4.0 2 1 2 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.23 KND89880.1 - 0.012 15.7 4.3 19 5.5 0.0 6.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KND89880.1 - 0.023 15.3 0.1 92 4.2 0.1 4.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 KND89880.1 - 0.027 15.1 9.5 11 6.7 0.0 6.6 6 2 1 8 8 7 0 Vacuolar 14 Fab1-binding region FANCF PF11107.8 KND89880.1 - 0.033 13.4 8.2 0.057 12.6 0.3 2.6 2 0 0 2 2 2 0 Fanconi anemia group F protein (FANCF) DUF3347 PF11827.8 KND89880.1 - 0.41 10.8 2.3 0.93 9.7 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) NUC173 PF08161.12 KND89880.1 - 1.5 8.5 7.9 5.2 6.7 0.0 4.3 5 2 0 5 5 5 0 NUC173 domain Glyco_hydro_75 PF07335.11 KND89881.1 - 8.6e-66 221.2 0.2 1e-65 221.0 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DHHC PF01529.20 KND89883.1 - 6.2e-36 123.5 6.9 1.3e-35 122.4 6.9 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4064 PF13273.6 KND89883.1 - 0.27 11.5 0.6 0.5 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Yip1 PF04893.17 KND89883.1 - 1.1 9.0 5.3 0.16 11.6 0.6 1.8 2 0 0 2 2 2 0 Yip1 domain ABC_tran PF00005.27 KND89884.1 - 9.1e-49 165.5 0.3 2.7e-26 92.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND89884.1 - 2.1e-14 53.5 0.0 6e-06 25.8 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND89884.1 - 3.5e-13 50.0 8.7 0.0029 17.5 0.1 4.7 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND89884.1 - 1.4e-09 38.8 0.1 7e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 KND89884.1 - 7.6e-09 35.4 0.2 3.6e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 KND89884.1 - 2.1e-07 31.0 0.0 0.0043 17.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KND89884.1 - 6.6e-07 29.0 0.5 0.0089 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND89884.1 - 2.1e-06 27.7 0.1 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 KND89884.1 - 1.2e-05 25.6 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KND89884.1 - 5.7e-05 23.4 0.1 0.74 10.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND89884.1 - 6.2e-05 23.6 0.1 0.098 13.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KND89884.1 - 0.00029 20.7 0.9 0.34 10.6 1.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 KND89884.1 - 0.0004 20.6 0.0 2.3 8.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 KND89884.1 - 0.0014 18.8 1.1 0.41 10.7 0.1 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 KND89884.1 - 0.0018 18.6 0.1 3.6 8.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.6 KND89884.1 - 0.0056 15.4 0.0 1.2 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND89884.1 - 0.0056 16.6 0.4 1.9 8.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 KND89884.1 - 0.0075 15.3 0.2 1.7 7.5 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 KND89884.1 - 0.0092 16.2 0.0 4.8 7.5 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 KND89884.1 - 0.0094 16.4 0.0 6.2 7.2 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND89884.1 - 0.0097 15.6 0.8 0.58 9.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KND89884.1 - 0.012 15.6 0.0 0.25 11.4 0.0 2.7 3 0 0 3 3 2 0 Dynamin family PduV-EutP PF10662.9 KND89884.1 - 0.014 15.2 0.0 0.92 9.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KND89884.1 - 0.025 13.8 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KND89884.1 - 0.028 14.6 0.0 6 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KND89884.1 - 0.032 14.6 0.1 2.7 8.3 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain AAA_27 PF13514.6 KND89884.1 - 0.032 13.8 0.7 8.5 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain CLASP_N PF12348.8 KND89884.1 - 0.037 13.6 0.0 1.2 8.6 0.0 2.7 3 0 0 3 3 2 0 CLASP N terminal AAA_30 PF13604.6 KND89884.1 - 0.04 13.6 3.6 3.1 7.5 0.0 3.3 3 1 0 3 3 2 0 AAA domain DUF3584 PF12128.8 KND89884.1 - 0.054 11.0 1.2 3.6 5.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_14 PF13173.6 KND89884.1 - 0.061 13.4 0.0 7.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KND89884.1 - 0.063 13.3 0.6 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KND89884.1 - 0.073 12.2 0.1 4.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 KND89884.1 - 0.1 12.5 0.2 17 5.3 0.2 2.8 3 0 0 3 3 2 0 NTPase ALF PF03752.13 KND89884.1 - 0.11 12.4 3.9 9.2 6.3 0.3 3.0 3 0 0 3 3 2 0 Short repeats of unknown function AAA_7 PF12775.7 KND89884.1 - 0.14 11.7 0.1 15 5.1 0.0 2.8 2 0 0 2 2 2 0 P-loop containing dynein motor region HEAT_EZ PF13513.6 KND89884.1 - 0.79 10.3 4.1 96 3.6 0.0 4.6 5 0 0 5 5 4 0 HEAT-like repeat Glyco_hydro_16 PF00722.21 KND89885.1 - 5.6e-15 55.3 3.9 8.9e-15 54.6 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 KND89885.1 - 0.2 11.7 0.1 0.45 10.6 0.1 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain TYW3 PF02676.14 KND89886.1 - 4.6e-74 248.4 0.0 5.5e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAPS_reduct PF01507.19 KND89887.1 - 2.4e-41 141.7 0.0 3.2e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.7 KND89888.1 - 6.3e-25 88.7 0.1 8.7e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND89888.1 - 5.2e-16 59.6 0.7 8.7e-16 58.8 0.7 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND89888.1 - 5e-09 36.3 1.0 1.2e-07 31.7 0.2 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND89888.1 - 0.00013 22.1 0.1 0.0011 19.1 0.1 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 KND89888.1 - 0.027 13.9 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) KOW PF00467.29 KND89888.1 - 0.031 14.2 0.9 0.056 13.4 0.9 1.4 1 0 0 1 1 1 0 KOW motif Acid_PPase PF12689.7 KND89888.1 - 0.2 11.5 0.0 0.63 9.9 0.0 1.8 1 1 0 1 1 1 0 Acid Phosphatase B12D PF06522.11 KND89889.1 - 0.099 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ferric_reduct PF01794.19 KND89890.1 - 5.6e-24 84.7 7.2 5.6e-24 84.7 7.2 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND89890.1 - 1.3e-17 64.4 0.0 3.4e-11 43.5 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KND89890.1 - 4.7e-07 29.9 0.0 3.8e-05 23.7 0.0 2.6 1 1 0 1 1 1 1 FAD-binding domain Spem1 PF15670.5 KND89890.1 - 0.16 11.6 0.2 0.25 10.9 0.2 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1690 PF07956.11 KND89891.1 - 4.4e-44 150.3 2.2 5.1e-44 150.1 2.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) NHase_beta PF02211.15 KND89891.1 - 0.14 12.1 0.3 0.17 11.8 0.3 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit DUF2203 PF09969.9 KND89891.1 - 0.29 11.9 4.0 2.6 8.8 4.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SNase PF00565.17 KND89892.1 - 9.5e-66 219.1 0.5 2.7e-16 60.0 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KND89892.1 - 9.1e-22 77.4 0.0 2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KND89892.1 - 0.042 13.1 0.1 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Wbp11 PF09429.10 KND89892.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.9 4 0 0 4 4 4 0 WW domain binding protein 11 TAL_FSA PF00923.19 KND89893.1 - 4.9e-92 308.3 1.1 6e-92 308.0 1.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase p450 PF00067.22 KND89894.1 - 3.8e-61 207.2 0.0 4.7e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.20 KND89895.1 - 2.3e-48 164.0 3.6 2.7e-48 163.7 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pet191_N PF10203.9 KND89896.1 - 8.4e-28 96.5 6.0 1.1e-27 96.1 6.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 KND89896.1 - 0.045 13.6 0.8 0.063 13.2 0.8 1.2 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 KND89896.1 - 0.071 12.9 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain NDUF_B7 PF05676.13 KND89896.1 - 0.09 12.5 3.3 0.98 9.2 0.1 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KND89896.1 - 2.6 8.1 10.4 0.54 10.3 1.2 2.9 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Abhydrolase_1 PF00561.20 KND89897.1 - 1.4e-24 87.2 0.1 2.4e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KND89897.1 - 3.9e-21 74.4 0.0 8.2e-21 73.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KND89897.1 - 4.7e-05 22.8 0.0 0.0029 16.9 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KND89897.1 - 0.001 18.8 0.1 0.038 13.7 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Vta1 PF04652.16 KND89897.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Vta1 like Metallophos PF00149.28 KND89898.1 - 1.3e-10 42.2 0.0 1.8e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND89898.1 - 3.8e-06 27.2 0.4 1.1e-05 25.7 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VARLMGL PF14383.6 KND89898.1 - 0.018 14.5 0.3 0.069 12.7 0.3 2.0 1 0 0 1 1 1 0 DUF761-associated sequence motif Peptidase_C12 PF01088.21 KND89900.1 - 7.7e-52 176.1 0.0 9.5e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MIP PF00230.20 KND89902.1 - 1.9e-24 86.6 8.2 2.5e-24 86.2 8.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_18 PF00704.28 KND89903.1 - 4.9e-18 65.9 0.1 1.4e-17 64.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SPX PF03105.19 KND89903.1 - 0.072 13.0 3.9 0.1 12.5 3.9 1.2 1 0 0 1 1 1 0 SPX domain DUF908 PF06012.12 KND89903.1 - 0.14 11.5 10.8 0.36 10.2 10.8 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Hormone_4 PF00220.17 KND89903.1 - 0.17 11.9 4.2 21 5.4 0.1 4.1 3 0 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain Apt1 PF10351.9 KND89903.1 - 0.42 9.4 8.9 0.6 8.9 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 KND89903.1 - 0.9 9.4 4.6 1.6 8.6 4.6 1.3 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 KND89903.1 - 3.8 6.8 10.8 6.2 6.1 10.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 KND89903.1 - 4.3 5.8 12.2 6 5.3 12.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF3433 PF11915.8 KND89905.1 - 4e-32 110.5 17.9 1.1e-28 99.6 4.9 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DUF2530 PF10745.9 KND89905.1 - 0.54 10.5 3.5 2.7 8.3 3.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pirin PF02678.16 KND89906.1 - 1.7e-26 92.3 1.3 4.2e-26 91.0 1.3 1.6 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KND89906.1 - 0.00048 19.8 3.0 0.039 13.7 0.5 3.1 2 1 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KND89906.1 - 0.0058 16.8 0.0 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Quercetinase C-terminal cupin domain ALO PF04030.14 KND89907.1 - 2.1e-91 306.3 1.1 3e-91 305.8 1.1 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KND89907.1 - 7.6e-30 103.5 0.1 1e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain CN_hydrolase PF00795.22 KND89908.1 - 1.1e-36 126.5 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SSF PF00474.17 KND89909.1 - 4.6e-24 85.0 27.4 6.9e-24 84.5 27.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Internalin_N PF12354.8 KND89909.1 - 4 7.6 6.3 1 9.5 0.4 3.2 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Pro_isomerase PF00160.21 KND89910.1 - 2.8e-51 173.9 0.0 3.2e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PI-PLC-X PF00388.19 KND89913.1 - 5.8e-55 184.9 0.0 9.3e-55 184.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KND89913.1 - 3.4e-39 133.7 0.0 5.8e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain ACPS PF01648.20 KND89914.1 - 4.1e-09 36.6 0.0 9.5e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_A22B PF04258.13 KND89915.1 - 1.7e-53 182.0 9.0 4.5e-33 115.0 2.1 2.4 2 1 0 2 2 2 2 Signal peptide peptidase Glyco_hydro_16 PF00722.21 KND89916.1 - 6.4e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KND89916.1 - 0.1 11.0 0.0 0.25 9.7 0.0 1.5 2 0 0 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) ketoacyl-synt PF00109.26 KND89917.1 - 4.4e-70 236.2 0.0 8.6e-70 235.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KND89917.1 - 3.3e-52 177.0 0.8 9.7e-52 175.5 0.1 2.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 KND89917.1 - 1.1e-50 172.6 0.0 2.2e-50 171.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KND89917.1 - 1.6e-43 149.4 1.8 2e-43 149.1 0.8 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND89917.1 - 1.5e-34 118.5 0.2 6e-34 116.6 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KND89917.1 - 2.3e-16 60.2 0.0 5.8e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KND89917.1 - 1.3e-12 47.6 0.1 3.6e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 KND89917.1 - 5.9e-05 23.0 0.1 0.00031 20.7 0.1 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND89917.1 - 6.1e-05 22.9 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 KND89917.1 - 0.00015 21.6 1.2 0.00056 19.7 1.2 2.0 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 KND89917.1 - 0.00022 20.8 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KND89917.1 - 0.011 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site Thiolase_N PF00108.23 KND89917.1 - 0.013 14.8 0.4 0.032 13.6 0.1 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain MFS_1 PF07690.16 KND89918.1 - 6.3e-27 94.4 44.2 4.2e-21 75.3 16.8 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily MtrF PF09472.10 KND89918.1 - 2.1 7.8 4.8 1.6 8.1 1.0 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Annexin PF00191.20 KND89919.1 - 2.6e-19 69.0 0.3 1.3e-05 25.1 0.0 4.5 4 0 0 4 4 4 4 Annexin GidB PF02527.15 KND89920.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 KND89921.1 - 5e-21 75.2 0.0 8.6e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89921.1 - 9.8e-13 48.6 0.0 3.9e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND89921.1 - 6.8e-11 42.7 0.0 1.7e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND89921.1 - 3.5e-08 34.1 0.0 3.2e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89921.1 - 6.2e-08 32.6 0.0 0.013 15.3 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 KND89921.1 - 0.002 17.6 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KND89921.1 - 0.045 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KND89921.1 - 0.055 13.0 0.0 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KND89921.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 KND89922.1 - 1.6e-23 83.2 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KND89922.1 - 0.0032 18.1 0.0 0.0072 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KND89922.1 - 0.0042 17.0 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND89922.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KND89922.1 - 0.14 12.9 0.0 0.36 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_C1_2 PF03051.15 KND89924.1 - 1.3e-148 495.4 0.0 1.5e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KND89924.1 - 8.2e-07 29.3 0.1 0.0046 17.1 0.0 2.5 2 1 0 2 2 2 2 Papain family cysteine protease DUF4296 PF14129.6 KND89924.1 - 0.026 15.1 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) eIF-5a PF01287.20 KND89925.1 - 7e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 KND89925.1 - 0.01 16.5 3.1 0.16 12.6 0.6 2.9 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red NFACT-C PF11923.8 KND89926.1 - 4.4e-41 139.1 0.1 4.4e-41 139.1 0.1 3.7 3 1 0 3 3 3 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KND89926.1 - 1.6e-31 109.2 0.0 3.8e-31 108.0 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KND89926.1 - 1.2e-26 93.6 17.8 1.2e-26 93.6 17.8 2.4 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) FAM76 PF16046.5 KND89927.1 - 0.0032 16.9 0.8 0.0053 16.1 0.8 1.4 1 0 0 1 1 1 1 FAM76 protein Tektin PF03148.14 KND89927.1 - 0.0063 15.3 1.7 0.011 14.5 1.7 1.4 1 0 0 1 1 1 1 Tektin family CLZ PF16526.5 KND89927.1 - 0.016 15.6 1.8 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels M_domain PF12938.7 KND89927.1 - 0.031 14.1 4.8 0.038 13.8 3.8 1.8 1 1 0 1 1 1 0 M domain of GW182 Cob_adeno_trans PF01923.18 KND89927.1 - 0.037 14.2 2.0 0.075 13.2 2.0 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF3294 PF07957.11 KND89927.1 - 0.21 11.3 5.7 0.31 10.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MukB PF04310.12 KND89927.1 - 0.46 10.2 3.7 0.22 11.3 1.3 1.6 2 0 0 2 2 2 0 MukB N-terminal TolA_bind_tri PF16331.5 KND89927.1 - 1.2 9.3 9.2 11 6.2 8.3 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation FMO-like PF00743.19 KND89928.1 - 3.6e-12 45.5 0.0 2.9e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 KND89928.1 - 5e-08 33.1 0.2 1.7e-06 28.1 0.0 3.2 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND89928.1 - 1.3e-06 28.5 0.1 1.2e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KND89928.1 - 1.9e-06 27.3 0.0 7.5e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KND89928.1 - 2.3e-06 27.1 0.0 1.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND89928.1 - 0.0019 17.5 0.1 0.028 13.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND89928.1 - 0.1 11.8 0.6 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 KND89928.1 - 0.22 12.1 0.1 4.5 7.9 0.3 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase hDGE_amylase PF14701.6 KND89929.1 - 1.5e-173 577.9 0.0 2.1e-173 577.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KND89929.1 - 3.5e-120 401.5 0.2 8.2e-120 400.2 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KND89929.1 - 4e-86 288.8 0.0 1.1e-85 287.4 0.0 1.8 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KND89929.1 - 2.5e-30 104.5 0.0 5.3e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme RSN1_7TM PF02714.15 KND89932.1 - 1.9e-72 243.8 26.1 3.6e-72 243.0 26.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KND89932.1 - 5.5e-38 130.9 0.0 8.2e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KND89932.1 - 5.9e-37 126.8 0.1 5.9e-37 126.8 0.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport MFS_1 PF07690.16 KND89935.1 - 2.7e-42 145.0 34.5 2.7e-42 145.0 34.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND89935.1 - 5.7e-10 38.2 3.8 9.2e-10 37.6 3.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND89935.1 - 6.4e-08 31.9 23.2 1.1e-07 31.2 23.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter 2-Hacid_dh_C PF02826.19 KND89936.1 - 9.5e-56 188.0 0.0 1.4e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND89936.1 - 7.2e-32 109.9 0.0 8.5e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND89936.1 - 4e-05 23.9 0.0 8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KND89936.1 - 0.00022 21.3 0.0 0.0005 20.2 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 KND89936.1 - 0.00089 18.9 0.0 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KND89936.1 - 0.0085 15.4 1.0 0.15 11.3 1.0 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 KND89936.1 - 0.0089 14.8 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase XdhC_C PF13478.6 KND89936.1 - 0.014 15.9 0.0 0.052 14.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain CoA_binding_2 PF13380.6 KND89936.1 - 0.075 13.5 0.0 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain Pyr_redox PF00070.27 KND89936.1 - 0.099 13.2 0.0 0.67 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KND89936.1 - 0.11 13.0 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 KND89936.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KND89936.1 - 0.26 12.1 1.6 18 6.2 0.0 2.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KND89936.1 - 0.3 11.2 1.0 1.4 9.0 0.2 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IBN_N PF03810.19 KND89937.1 - 2.8e-08 33.6 0.1 3e-07 30.3 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ribosomal_60s PF00428.19 KND89937.1 - 0.029 14.9 0.7 0.11 13.1 0.7 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cse1 PF08506.10 KND89937.1 - 0.042 12.7 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 0 Cse1 Xpo1 PF08389.12 KND89937.1 - 0.06 13.4 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein Transp_cyt_pur PF02133.15 KND89938.1 - 3.6e-152 507.2 38.0 4.2e-152 506.9 38.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MTP18 PF10558.9 KND89939.1 - 6e-83 277.0 0.3 7.4e-83 276.7 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Photo_RC PF00124.19 KND89939.1 - 0.057 12.6 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein zf-AN1 PF01428.16 KND89940.1 - 1.2e-23 83.0 27.8 1.7e-12 47.3 9.1 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Remorin_C PF03763.13 KND89940.1 - 0.0011 18.8 3.8 0.0022 17.8 3.8 1.4 1 0 0 1 1 1 1 Remorin, C-terminal region Transp_Tc5_C PF04236.15 KND89940.1 - 0.12 12.7 15.8 0.16 12.3 3.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.21 KND89940.1 - 0.79 10.0 23.4 0.44 10.8 6.8 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Rad4 PF03835.15 KND89941.1 - 5.3e-29 100.8 0.7 2.1e-28 98.8 0.6 2.1 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KND89941.1 - 1.6e-25 89.3 0.4 3.8e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KND89941.1 - 2.4e-16 59.3 0.3 2.4e-16 59.3 0.3 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KND89941.1 - 8e-10 39.5 0.0 8e-10 39.5 0.0 5.1 6 1 0 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KND89941.1 - 0.00035 21.0 0.0 0.0024 18.3 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily IBR PF01485.21 KND89942.1 - 4.3 7.6 39.8 0.04 14.1 9.5 3.6 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain FLYWCH_u PF16662.5 KND89943.1 - 0.0024 17.9 1.8 1.2 9.3 0.1 3.1 3 0 0 3 3 3 2 FLYWCH-type zinc finger-containing protein 1 Dcc1 PF09724.9 KND89944.1 - 5.7e-09 35.7 0.1 6.4e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HORMA PF02301.18 KND89945.1 - 2.2e-05 24.2 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain TadZ_N PF16968.5 KND89945.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal PI31_Prot_N PF11566.8 KND89946.1 - 5.1e-60 202.0 0.0 6.3e-60 201.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KND89946.1 - 2.2e-19 70.4 16.8 2.2e-19 70.4 16.8 2.4 3 0 0 3 3 3 1 PI31 proteasome regulator SLX9 PF15341.6 KND89947.1 - 2.5e-35 121.7 6.5 4.9e-35 120.8 6.5 1.5 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Peptidase_C48 PF02902.19 KND89948.1 - 1.3e-17 64.3 0.0 4.6e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pam17 PF08566.10 KND89949.1 - 2e-64 216.4 0.0 2.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ThiF PF00899.21 KND89950.1 - 1.5e-57 194.8 0.0 2.2e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KND89950.1 - 4.2e-12 46.5 0.0 2.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain UDPG_MGDP_dh_N PF03721.14 KND89950.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 KND89950.1 - 0.0065 16.9 0.0 0.025 15.0 0.0 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KND89950.1 - 0.036 14.1 0.1 0.13 12.4 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KND89950.1 - 0.045 13.0 0.1 0.064 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KND89950.1 - 0.058 12.6 0.2 0.097 11.9 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KND89950.1 - 0.091 12.4 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KND89950.1 - 0.14 12.7 0.9 0.29 11.7 0.9 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GPS2_interact PF15784.5 KND89950.1 - 0.15 12.5 0.5 0.26 11.7 0.5 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain PKcGMP_CC PF16808.5 KND89950.1 - 0.55 10.1 1.9 1.4 8.8 1.9 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Alginate_lyase2 PF08787.11 KND89951.1 - 2.1e-10 40.9 0.0 3.6e-06 27.0 0.0 2.1 1 1 1 2 2 2 2 Alginate lyase HNH_2 PF13391.6 KND89952.1 - 4.1e-08 33.2 0.0 9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease TRAM_LAG1_CLN8 PF03798.16 KND89953.1 - 6.6e-44 150.0 19.0 6.6e-44 150.0 19.0 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KND89953.1 - 3e-16 58.8 0.0 7.9e-16 57.5 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein GFA PF04828.14 KND89954.1 - 5.7e-10 39.4 1.3 5.7e-10 39.4 1.3 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme D_CNTX PF17492.2 KND89954.1 - 0.091 12.9 0.2 0.091 12.9 0.2 2.5 2 1 0 2 2 2 0 Delta Ctenitoxins Caps_synth PF05704.12 KND89955.1 - 1.4e-06 28.0 0.0 2.9e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KND89955.1 - 0.0018 18.8 0.0 0.003 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif C2 PF00168.30 KND89956.1 - 2.5e-10 40.6 0.0 4.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain PAD PF03068.15 KND89957.1 - 1.7e-116 389.5 0.0 2e-116 389.2 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) CoA_transf_3 PF02515.17 KND89958.1 - 8.8e-121 403.5 0.0 9.9e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III NACHT PF05729.12 KND89959.1 - 1.7e-13 50.8 0.0 4.4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 KND89959.1 - 1.2e-06 29.0 0.6 1.8e-05 25.3 0.1 2.7 2 1 0 2 2 2 1 NLRC4 helical domain HD2 HEAT_2 PF13646.6 KND89959.1 - 2.6e-05 24.5 3.7 0.0001 22.6 0.1 3.2 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 KND89959.1 - 0.00046 20.2 0.1 0.68 10.3 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KND89959.1 - 0.0012 19.3 0.1 0.0064 17.0 0.0 2.4 3 0 0 3 3 1 1 HEAT-like repeat NB-ARC PF00931.22 KND89959.1 - 0.0013 18.0 0.3 0.0042 16.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KND89959.1 - 0.003 17.8 0.1 0.016 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND89959.1 - 0.0062 16.9 3.2 0.11 12.9 1.2 3.3 2 1 0 2 2 2 1 AAA ATPase domain Cnd1 PF12717.7 KND89959.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 AAA_18 PF13238.6 KND89959.1 - 0.15 12.6 0.0 0.54 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KND89959.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.24 KND89960.1 - 9.2e-114 380.8 19.4 2.6e-113 379.3 19.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND89960.1 - 1.5e-17 63.6 40.6 1.7e-10 40.4 16.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_60s PF00428.19 KND89961.1 - 0.55 10.9 14.6 0.07 13.7 4.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF2627 PF11118.8 KND89962.1 - 0.011 16.3 0.6 0.023 15.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Lipase_3 PF01764.25 KND89963.1 - 1.1e-14 54.6 0.0 1.9e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 KND89963.1 - 0.082 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 KND89963.1 - 0.33 11.5 10.0 0.58 10.7 9.9 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family GRDP-like PF07173.12 KND89965.1 - 1e-18 68.3 0.0 2.1e-16 60.8 0.0 2.3 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like ABC_tran PF00005.27 KND89966.1 - 5.4e-33 114.4 0.0 1.2e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KND89966.1 - 4.1e-06 26.6 0.1 5.4e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KND89966.1 - 1.1e-05 24.9 0.1 0.0034 16.8 0.0 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 KND89966.1 - 4.4e-05 23.7 0.0 9.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KND89966.1 - 0.011 15.5 0.2 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 KND89966.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KND89966.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KND89966.1 - 0.036 14.3 0.2 0.21 11.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND89966.1 - 0.038 14.4 0.5 0.14 12.5 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KND89966.1 - 0.086 12.8 0.1 3.7 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 KND89966.1 - 0.12 12.1 0.7 13 5.5 0.2 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 KND89966.1 - 0.13 12.1 0.4 0.7 9.6 0.3 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KND89966.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MFS_1 PF07690.16 KND89967.1 - 3.7e-40 138.0 34.2 3.7e-40 138.0 34.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND89967.1 - 7.1e-17 61.4 6.8 7.1e-17 61.4 6.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND89967.1 - 3.1e-06 25.9 7.2 6.6e-06 24.8 7.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PAP2 PF01569.21 KND89967.1 - 0.025 14.4 0.5 0.025 14.4 0.5 3.3 4 1 0 4 4 4 0 PAP2 superfamily Pilin_PilA PF14245.6 KND89969.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV pilin PilA AA_permease_2 PF13520.6 KND89970.1 - 4.3e-50 170.8 50.2 5.1e-50 170.5 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND89970.1 - 4.1e-25 88.3 45.9 5.2e-25 88.0 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease Iso_dh PF00180.20 KND89971.1 - 1e-78 265.0 0.0 1.5e-78 264.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 KND89971.1 - 2.3e-67 227.1 0.0 3.8e-67 226.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89971.1 - 1.2e-49 168.9 0.0 2.3e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND89971.1 - 0.0011 17.9 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KND89971.1 - 0.054 12.8 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like AAA_3 PF07726.11 KND89971.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ecm29 PF13001.7 KND89972.1 - 1.4e-144 482.5 0.1 3.1e-143 478.1 0.1 2.5 2 0 0 2 2 2 1 Proteasome stabiliser Thioredoxin_7 PF13899.6 KND89972.1 - 1.5e-15 57.1 0.1 4e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 KND89972.1 - 3.8e-13 49.0 0.0 6.5e-12 45.1 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 KND89972.1 - 7.4e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain HEAT_EZ PF13513.6 KND89972.1 - 0.0057 17.1 14.1 0.34 11.4 0.0 7.7 7 1 0 7 7 7 1 HEAT-like repeat Thioredox_DsbH PF03190.15 KND89972.1 - 0.11 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF255 MRC1 PF09444.10 KND89972.1 - 0.91 10.0 9.7 2.7 8.5 9.7 1.8 1 0 0 1 1 1 0 MRC1-like domain DAO PF01266.24 KND89974.1 - 5.6e-18 65.6 0.0 7.2e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NatB_MDM20 PF09797.9 KND89975.1 - 5.3e-45 154.0 0.0 9.7e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_M35 PF02102.15 KND89976.1 - 7.7e-70 235.6 12.9 1e-69 235.2 12.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KND89976.1 - 1.3e-34 119.9 5.4 2.2e-34 119.1 5.4 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Acetyltransf_1 PF00583.25 KND89977.1 - 4.6e-09 36.5 0.0 1.2e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND89977.1 - 4.9e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND89977.1 - 1.1e-06 28.9 0.0 3.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND89977.1 - 0.0039 17.3 0.0 0.66 10.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND89977.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein DUF3445 PF11927.8 KND89978.1 - 2.6e-72 243.1 0.0 3.6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SWIB PF02201.18 KND89978.1 - 1.6e-28 98.4 0.2 2.8e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain zf-C3HC4_3 PF13920.6 KND89978.1 - 3.7e-05 23.5 8.8 3.7e-05 23.5 8.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribonuc_2-5A PF06479.12 KND89979.1 - 3.1e-43 147.0 0.0 1.3e-42 145.0 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KND89979.1 - 9.3e-41 139.9 0.0 2.1e-39 135.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND89979.1 - 3.3e-21 75.7 0.0 3.7e-20 72.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 KND89979.1 - 1.6e-06 27.8 1.7 0.0019 18.0 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KND89979.1 - 4.5e-05 23.1 0.5 33 3.9 0.1 2.8 2 1 0 2 2 2 0 PQQ-like domain Kdo PF06293.14 KND89979.1 - 0.0017 17.7 0.0 0.0043 16.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND89979.1 - 0.012 14.5 0.0 0.012 14.5 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 KND89979.1 - 0.075 12.9 0.1 0.075 12.9 0.1 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family eIF2A PF08662.11 KND89980.1 - 7.3e-39 133.7 2.0 1.3e-36 126.3 0.1 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KND89980.1 - 0.003 15.6 0.0 0.0067 14.5 0.0 1.5 1 0 0 1 1 1 1 IKI3 family RRM_1 PF00076.22 KND89980.1 - 0.0044 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KND89980.1 - 0.18 12.8 1.6 9.1 7.3 0.0 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat tRNA-synt_2 PF00152.20 KND89981.1 - 5.6e-75 252.3 0.2 9.1e-75 251.6 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND89981.1 - 2.4e-10 40.3 0.0 4.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KND89981.1 - 4.3e-08 33.0 0.2 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF3069 PF11269.8 KND89981.1 - 0.024 14.9 0.1 0.21 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) WBS_methylT PF12589.8 KND89982.1 - 1.3e-13 51.5 3.3 2.3e-13 50.7 3.3 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KND89982.1 - 2.9e-11 43.9 0.0 7.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND89982.1 - 6.4e-10 39.6 0.0 1.9e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND89982.1 - 9.1e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KND89982.1 - 0.00016 22.4 0.0 0.00044 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND89982.1 - 0.001 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND89982.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 KND89982.1 - 0.019 14.2 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KND89982.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Erv26 PF04148.13 KND89983.1 - 1.9e-89 298.9 1.2 2.4e-89 298.6 1.2 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF3377 PF11857.8 KND89983.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Cytochrom_C_asm PF01578.20 KND89983.1 - 0.31 10.8 7.0 0.14 11.9 2.2 2.1 2 0 0 2 2 2 0 Cytochrome C assembly protein Polysacc_synt_C PF14667.6 KND89983.1 - 3.8 7.6 10.4 1.1 9.3 6.7 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Fungal_trans_2 PF11951.8 KND89985.1 - 7.1e-21 74.5 0.0 9.6e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND89985.1 - 0.011 15.9 11.7 0.022 14.9 11.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_ATPase_C PF00689.21 KND89986.1 - 3.7e-42 144.1 8.3 3.7e-42 144.1 8.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KND89986.1 - 2.1e-39 134.9 0.3 2.1e-39 134.9 0.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KND89986.1 - 1.4e-20 74.5 1.0 1.2e-09 38.8 0.2 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND89986.1 - 1.7e-19 69.7 0.0 3.6e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KND89986.1 - 1.5e-11 43.8 0.0 3.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND89986.1 - 0.00066 19.5 0.2 0.0012 18.7 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND89986.1 - 0.0096 16.3 0.1 1.3 9.4 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Nucleos_tra2_N PF01773.20 KND89986.1 - 2.7 8.7 9.2 18 6.0 0.1 3.8 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus FA_desaturase PF00487.24 KND89987.1 - 2.6e-23 83.2 20.4 5.2e-23 82.2 20.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KND89987.1 - 1.8e-07 31.5 0.0 8.1e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) HTH_28 PF13518.6 KND89988.1 - 0.078 13.1 0.8 94 3.3 0.0 3.6 3 0 0 3 3 3 0 Helix-turn-helix domain RabGAP-TBC PF00566.18 KND89989.1 - 3e-31 108.8 0.0 4.4e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KND89989.1 - 2.6e-08 32.6 0.3 3.9e-08 32.0 0.3 1.2 1 0 0 1 1 1 1 SBE2, cell-wall formation SIKE PF05769.11 KND89989.1 - 1 9.3 3.2 6.3 6.7 3.2 2.0 1 1 0 1 1 1 0 SIKE family Cpn60_TCP1 PF00118.24 KND89990.1 - 3.4e-135 451.4 12.8 4.2e-135 451.1 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 KND89990.1 - 0.018 15.2 0.2 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 KND89990.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat TRAPPC10 PF12584.8 KND89991.1 - 3.1e-25 88.7 0.0 5.6e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 KND89991.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Gag_p12 PF01141.18 KND89992.1 - 0.018 15.4 0.4 0.018 15.4 0.4 2.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 ADH_N PF08240.12 KND89993.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 KND89994.1 - 1.3e-10 41.1 0.0 5.6e-06 25.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain HsbA PF12296.8 KND89995.1 - 2.1e-28 99.2 5.6 3.1e-28 98.6 5.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Glyco_transf_20 PF00982.21 KND89997.1 - 7.4e-164 545.9 0.0 1e-163 545.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KND89997.1 - 2.5e-40 138.0 0.0 5.8e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Aminotran_4 PF01063.19 KND89998.1 - 1.2e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MutS_V PF00488.21 KND89999.1 - 3.6e-61 206.5 0.1 6.7e-61 205.6 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND89999.1 - 9.7e-32 110.7 0.1 2.5e-31 109.4 0.1 1.7 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 KND89999.1 - 1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KND89999.1 - 1e-05 25.8 1.1 5.5e-05 23.5 0.0 2.7 3 1 0 3 3 3 1 MutS domain II AAA_27 PF13514.6 KND89999.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KND90000.1 - 6.1e-54 178.8 33.2 5.4e-09 36.5 0.5 9.3 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90000.1 - 6.9e-17 61.5 9.7 0.0072 16.6 0.1 6.3 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain FAR1 PF03101.15 KND90000.1 - 1.7e-08 35.0 0.6 4.9e-08 33.6 0.6 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Ge1_WD40 PF16529.5 KND90000.1 - 1.7e-06 27.3 0.4 2.5 7.0 0.1 5.4 3 3 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND90000.1 - 2e-05 24.5 1.4 0.00064 19.7 0.1 3.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KND90000.1 - 0.00042 19.1 4.3 1.2 7.6 0.3 4.8 4 2 1 5 5 5 2 Nucleoporin Nup120/160 FAD_binding_9 PF08021.11 KND90000.1 - 0.036 14.3 0.1 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 KND90000.1 - 0.039 13.3 0.0 7.6 5.8 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Peptidase_M20 PF01546.28 KND90001.1 - 1.3e-19 70.7 2.0 1.5e-18 67.3 2.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND90001.1 - 7.3e-19 67.7 0.0 1.7e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KND90001.1 - 0.00016 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 AP_endonuc_2 PF01261.24 KND90002.1 - 5.4e-33 114.2 0.0 7.5e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DCR PF14047.6 KND90002.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region NmrA PF05368.13 KND90003.1 - 1e-20 74.3 0.2 1.8e-20 73.5 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND90003.1 - 2.7e-13 50.2 0.0 4.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KND90003.1 - 0.0036 17.5 0.1 0.0067 16.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3394 PF11874.8 KND90003.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) IF-2B PF01008.17 KND90004.1 - 1.5e-76 257.3 0.1 1.7e-76 257.1 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family RhoGEF PF00621.20 KND90005.1 - 9.8e-27 94.4 0.0 1.7e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KND90005.1 - 0.01 15.6 0.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3507) Nod1 PF17114.5 KND90005.1 - 0.062 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Exo5 PF09810.9 KND90006.1 - 4.9e-137 457.3 0.0 5.8e-137 457.1 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KND90006.1 - 0.033 14.1 0.1 10 6.0 0.1 2.9 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily ThiF PF00899.21 KND90007.1 - 7.2e-115 382.5 0.0 1.7e-75 253.5 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KND90007.1 - 2e-91 306.4 3.8 3e-91 305.8 2.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 KND90007.1 - 1.2e-31 109.3 0.2 2.3e-31 108.4 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 KND90007.1 - 3.4e-31 107.3 0.0 9.5e-31 105.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 KND90007.1 - 5.2e-25 87.4 0.7 1.3e-24 86.1 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 KND90007.1 - 0.057 13.9 0.0 0.77 10.2 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Omega-toxin PF06357.11 KND90009.1 - 0.028 14.2 0.3 0.056 13.2 0.3 1.4 1 0 0 1 1 1 0 Omega-atracotoxin GST_N_2 PF13409.6 KND90011.1 - 1.7e-21 76.3 0.0 4.4e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND90011.1 - 1e-14 54.3 0.0 2e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND90011.1 - 9.7e-06 25.9 0.1 0.00041 20.7 0.1 2.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KND90011.1 - 7.8e-05 22.8 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND90011.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KND90011.1 - 0.0092 16.5 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CAF20 PF17052.5 KND90012.1 - 6.9 6.8 8.9 20 5.3 5.5 3.1 3 1 0 3 3 3 0 Cap associated factor Sec1 PF00995.23 KND90013.1 - 1.9e-116 390.6 0.0 2.2e-116 390.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.12 KND90013.1 - 0.042 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) G-patch PF01585.23 KND90014.1 - 3.1e-06 27.0 0.4 8.6e-06 25.6 0.4 1.8 1 0 0 1 1 1 1 G-patch domain NAD_binding_10 PF13460.6 KND90015.1 - 4.8e-22 78.7 0.2 6.7e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND90015.1 - 0.0011 18.5 0.0 0.0028 17.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KND90015.1 - 0.045 12.9 0.1 0.27 10.4 0.0 2.2 2 1 1 3 3 3 0 Male sterility protein NmrA PF05368.13 KND90015.1 - 0.09 12.3 0.2 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family DUF4529 PF15032.6 KND90016.1 - 0.2 10.7 0.1 0.25 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) HTH_ABP1_N PF18107.1 KND90017.1 - 9.6e-24 82.9 1.9 9.6e-24 82.9 1.9 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 KND90017.1 - 5e-18 64.9 1.2 3.1e-17 62.3 0.2 2.7 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF3736 PF12540.8 KND90017.1 - 0.02 15.0 9.0 0.43 10.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3736) Mito_fiss_reg PF05308.11 KND90017.1 - 0.19 11.8 4.8 0.047 13.8 1.8 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KND90017.1 - 1.1 9.2 7.6 2.2 8.3 7.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EAP30 PF04157.16 KND90018.1 - 9.6e-42 142.9 0.1 1.2e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 KND90018.1 - 5.3e-23 80.2 1.6 5.3e-23 80.2 1.6 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 KND90018.1 - 3.1e-22 78.6 0.0 5.3e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 KND90018.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-Sec23_Sec24 PF04810.15 KND90018.1 - 0.36 10.9 8.8 0.14 12.2 0.7 2.5 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 KND90018.1 - 2.4 7.6 19.4 1.2 8.5 7.2 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others SAC3_GANP PF03399.16 KND90019.1 - 1.6e-24 86.8 2.4 2.4e-22 79.7 2.5 2.2 1 1 0 1 1 1 1 SAC3/GANP family NACHT_N PF17100.5 KND90020.1 - 2.4e-52 178.0 2.0 4.4e-52 177.1 2.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase WD40 PF00400.32 KND90020.1 - 2.1e-42 142.3 39.8 2.9e-10 40.6 0.3 12.1 13 0 0 13 13 12 7 WD domain, G-beta repeat NACHT PF05729.12 KND90020.1 - 1.2e-15 57.8 0.1 3.6e-15 56.3 0.1 1.8 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KND90020.1 - 5.4e-15 55.5 5.6 0.0045 17.3 0.0 7.9 5 3 3 9 9 8 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KND90020.1 - 1.4e-07 30.4 1.0 0.0057 15.2 0.2 4.0 3 1 1 4 4 4 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KND90020.1 - 9e-05 21.6 4.7 0.51 9.2 0.0 4.6 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KND90020.1 - 0.0002 20.8 0.0 0.61 9.4 0.0 3.7 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 KND90020.1 - 0.00094 17.9 12.5 2 7.0 0.1 5.9 3 2 3 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.12 KND90020.1 - 0.0018 18.2 0.6 11 6.1 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 KND90020.1 - 0.0047 15.9 10.1 3.4 6.5 0.1 6.1 4 3 3 7 7 7 1 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 KND90020.1 - 0.007 16.0 9.5 0.59 9.7 1.4 4.0 1 1 2 3 3 3 2 PQQ-like domain Nbas_N PF15492.6 KND90020.1 - 0.008 15.5 2.7 29 3.9 0.0 4.6 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.11 KND90020.1 - 0.008 15.3 0.3 1.2 8.1 0.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1513) RNA_helicase PF00910.22 KND90020.1 - 0.061 13.7 0.0 1 9.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase CDtoxinA PF03498.14 KND90020.1 - 0.1 12.2 0.1 10 5.7 0.0 3.2 2 1 0 3 3 3 0 Cytolethal distending toxin A/C domain Utp8 PF10395.9 KND90020.1 - 0.18 10.3 0.1 8 4.8 0.0 2.2 2 0 0 2 2 2 0 Utp8 family PQQ_3 PF13570.6 KND90020.1 - 1.4 9.5 5.3 17 6.1 0.1 4.7 6 0 0 6 6 5 0 PQQ-like domain RicinB_lectin_2 PF14200.6 KND90020.1 - 3.7 8.3 6.0 56 4.5 0.0 4.7 6 0 0 6 6 5 0 Ricin-type beta-trefoil lectin domain-like SH3_1 PF00018.28 KND90021.1 - 9e-14 50.8 0.0 9.8e-06 25.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.24 KND90021.1 - 1.2e-13 51.1 0.1 1.8e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 KND90021.1 - 6.6e-06 25.9 0.3 0.0006 19.6 0.0 2.8 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 KND90021.1 - 4.3e-05 23.1 0.0 0.00058 19.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 KND90021.1 - 0.00013 21.9 0.1 0.00025 20.9 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DHHW PF14286.6 KND90021.1 - 0.0076 15.6 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 DHHW protein EPL1 PF10513.9 KND90021.1 - 0.15 12.5 1.4 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_S9 PF00326.21 KND90023.1 - 1.5e-41 142.2 0.0 2.4e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND90023.1 - 9.4e-05 22.2 1.2 0.0013 18.4 1.2 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 KND90023.1 - 0.011 14.9 0.0 0.16 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 KND90023.1 - 0.026 14.4 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 KND90023.1 - 0.2 10.3 0.0 1.4 7.5 0.0 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Serglycin PF04360.12 KND90024.1 - 1.8 8.5 7.1 0.29 11.1 3.4 1.5 2 0 0 2 2 2 0 Serglycin F-box-like PF12937.7 KND90026.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND90026.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain 7tm_2 PF00002.24 KND90027.1 - 2.8e-11 43.2 5.5 4.9e-11 42.4 5.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4229 PF14012.6 KND90027.1 - 0.013 15.6 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Dicty_CAR PF05462.11 KND90027.1 - 0.038 13.1 9.6 0.45 9.6 1.2 2.4 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Git3 PF11710.8 KND90027.1 - 0.096 12.5 10.9 0.23 11.2 10.9 1.7 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 4HBT PF03061.22 KND90028.1 - 1.9e-06 28.1 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KND90028.1 - 0.0043 16.4 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase NAD_Gly3P_dh_N PF01210.23 KND90029.1 - 2.4e-44 151.1 0.0 3.7e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 KND90029.1 - 2.8e-41 141.1 0.2 5.5e-41 140.2 0.2 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.6 KND90030.1 - 3.3e-05 24.2 0.0 0.005 17.2 0.1 2.4 2 0 0 2 2 2 2 AIG2-like family Tail_VII PF17091.5 KND90030.1 - 0.067 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Inovirus G7P protein DUF4175 PF13779.6 KND90032.1 - 0.11 10.4 2.8 0.13 10.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DLH PF01738.18 KND90033.1 - 1.4e-05 24.8 0.1 0.00023 20.8 0.1 2.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KND90033.1 - 3.8e-05 23.4 0.0 4.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KND90034.1 - 1.4e-18 67.5 0.0 1.8e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND90034.1 - 4.7e-14 52.2 0.0 8.7e-13 48.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND90034.1 - 4e-07 30.9 0.0 5.3e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KND90034.1 - 3e-05 23.8 0.1 0.28 10.9 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.11 KND90034.1 - 0.00025 20.5 0.0 0.00074 18.9 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 KND90034.1 - 0.00042 19.9 0.0 0.009 15.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KND90034.1 - 0.00042 20.2 0.0 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 KND90034.1 - 0.00066 19.3 0.0 0.0046 16.5 0.0 1.9 1 1 1 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 KND90034.1 - 0.0094 15.6 0.2 0.026 14.2 0.2 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) NAD_binding_10 PF13460.6 KND90035.1 - 8e-09 35.6 0.1 1.4e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND90035.1 - 1.3e-08 34.7 0.0 2.7e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 KND90035.1 - 0.00033 20.9 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KND90035.1 - 0.002 17.6 0.1 0.0029 17.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KND90035.1 - 0.078 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ntox1 PF15500.6 KND90035.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 GDP_Man_Dehyd PF16363.5 KND90035.1 - 0.2 11.0 0.1 0.29 10.5 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KND90036.1 - 1.9e-49 168.5 44.9 1.9e-49 168.5 44.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND90036.1 - 1.1e-10 40.6 14.6 1.4e-10 40.3 14.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KND90036.1 - 0.058 11.7 14.4 0.017 13.4 2.6 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4407 PF14362.6 KND90036.1 - 6.5 6.0 6.5 0.57 9.5 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Chromo PF00385.24 KND90037.1 - 1.7e-06 27.9 0.5 1.7e-06 27.9 0.5 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain RRP7 PF12923.7 KND90037.1 - 1.9 8.7 5.6 16 5.6 1.6 2.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 KND90038.1 - 0.00041 20.1 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.27 KND90039.1 - 2e-30 106.1 0.0 3.6e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KND90039.1 - 1.5e-18 67.4 4.3 1.5e-18 67.4 4.3 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KND90039.1 - 0.00021 20.8 0.0 0.002 17.6 0.0 1.5 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KND90039.1 - 0.0032 17.2 0.2 0.012 15.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND90039.1 - 0.013 15.8 0.4 0.073 13.3 0.4 2.1 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KND90039.1 - 0.04 12.8 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 KND90039.1 - 0.041 14.0 0.2 0.082 13.0 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KND90039.1 - 0.053 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 KND90039.1 - 0.14 12.6 0.6 0.44 10.9 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M20 PF01546.28 KND90040.1 - 1e-28 100.5 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND90040.1 - 1.5e-11 44.2 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Acetyltransf_1 PF00583.25 KND90041.1 - 1.7e-10 41.1 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND90041.1 - 3e-10 40.4 0.0 4.5e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND90041.1 - 1.3e-08 34.8 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KND90041.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KND90041.1 - 0.026 14.7 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HPP PF04982.13 KND90043.1 - 1.8e-41 141.1 5.6 3.4e-41 140.3 5.6 1.4 1 0 0 1 1 1 1 HPP family DUF2828 PF11443.8 KND90044.1 - 2.6e-250 831.9 0.0 3.2e-250 831.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Prefoldin PF02996.17 KND90044.1 - 0.078 12.9 2.3 4.4 7.2 0.2 3.4 3 1 1 4 4 4 0 Prefoldin subunit ThrE PF06738.12 KND90045.1 - 9.8e-74 247.7 5.2 5.5e-70 235.5 0.6 2.7 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KND90045.1 - 1.7e-06 28.2 0.6 1.7e-06 28.2 0.6 3.4 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE Asp PF00026.23 KND90046.1 - 2.6e-78 263.6 9.0 3.1e-78 263.4 9.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND90046.1 - 8.1e-12 45.7 3.9 4.3e-07 30.3 0.0 3.2 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND90046.1 - 0.00015 22.4 1.8 0.68 10.6 0.3 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KND90046.1 - 0.0095 15.7 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal PBP PF01161.20 KND90047.1 - 3.5e-06 27.3 0.4 4.8e-06 26.9 0.3 1.6 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein GFO_IDH_MocA PF01408.22 KND90048.1 - 0.0077 17.0 0.0 0.0099 16.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold G6PD_N PF00479.22 KND90048.1 - 0.035 14.7 0.0 0.04 14.6 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase_Tyr PF07714.17 KND90049.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND90049.1 - 0.00021 20.7 0.0 0.00092 18.7 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.23 KND90049.1 - 0.0046 16.9 0.1 0.0074 16.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND90049.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 KND90049.1 - 0.21 10.6 0.0 0.47 9.5 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Peptidase_C48 PF02902.19 KND90050.1 - 0.029 14.2 0.1 0.036 13.9 0.1 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain APH PF01636.23 KND90051.1 - 4.1e-06 26.9 0.6 2e-05 24.6 0.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND90051.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND90051.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Fungal_trans_2 PF11951.8 KND90052.1 - 4.1e-15 55.5 4.7 6.1e-15 54.9 4.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KND90052.1 - 1e-08 34.5 21.9 0.001 18.0 2.6 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Zn_clus PF00172.18 KND90052.1 - 1.4e-06 28.3 10.1 3e-06 27.3 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNO PF01174.19 KND90053.1 - 2.7e-54 183.9 0.0 1.1e-52 178.6 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KND90053.1 - 2.7e-08 33.7 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KND90053.1 - 4.6e-05 23.3 0.3 6.6e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Cupin_6 PF12852.7 KND90053.1 - 0.056 13.2 0.2 0.087 12.5 0.2 1.4 1 0 0 1 1 1 0 Cupin Peptidase_S51 PF03575.17 KND90053.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 SOR_SNZ PF01680.17 KND90054.1 - 1.4e-103 345.1 7.3 2e-103 344.6 7.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KND90054.1 - 2.1e-09 37.0 5.7 1.4e-07 31.1 0.3 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 KND90054.1 - 0.00035 20.6 0.0 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 KND90054.1 - 0.00093 18.4 1.0 0.41 9.7 0.0 2.4 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KND90054.1 - 0.0033 16.9 0.3 0.16 11.4 0.0 2.5 2 1 0 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.21 KND90054.1 - 0.0038 16.5 0.4 0.042 13.0 0.0 2.4 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 KND90054.1 - 0.017 14.3 1.6 0.17 11.1 0.0 2.7 2 2 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 KND90054.1 - 0.041 13.5 0.4 0.058 13.0 0.4 1.5 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.17 KND90054.1 - 0.073 12.4 1.8 0.69 9.2 0.1 2.6 2 2 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 KND90054.1 - 0.26 10.6 11.3 0.55 9.6 2.2 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase AAT PF03417.16 KND90055.1 - 2.3e-18 66.7 0.0 9.2e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans_2 PF11951.8 KND90056.1 - 1.8e-09 36.9 0.2 5e-06 25.6 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90056.1 - 0.00093 19.3 10.9 0.0022 18.1 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.13 KND90057.1 - 9.8e-14 51.8 0.0 1.3e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF4601 PF15373.6 KND90057.1 - 0.21 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) RRM_1 PF00076.22 KND90058.1 - 2.3e-46 155.5 0.0 1.4e-16 60.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND90058.1 - 2e-07 30.9 0.1 0.0023 17.9 0.1 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KND90058.1 - 0.00021 21.3 0.0 0.0018 18.3 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 KND90058.1 - 0.00022 21.3 0.0 0.055 13.6 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 KND90058.1 - 0.00033 20.5 0.0 0.053 13.4 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 KND90058.1 - 0.042 13.4 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_2 PF07992.14 KND90060.1 - 9.8e-09 34.9 0.1 8.8e-07 28.4 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KND90060.1 - 1.8e-06 26.7 0.0 1.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KND90060.1 - 1.2e-05 25.5 0.1 0.00012 22.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND90060.1 - 0.00011 21.6 0.5 0.013 14.8 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND90060.1 - 0.00059 19.9 0.0 0.072 13.1 0.0 3.4 4 1 0 4 4 4 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KND90060.1 - 0.0037 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 KND90060.1 - 0.016 15.8 0.2 0.57 10.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KND90060.1 - 0.025 14.7 0.0 0.22 11.6 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase PI-PLC-X PF00388.19 KND90061.1 - 2.9e-44 150.2 0.0 4.6e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KND90061.1 - 9.5e-37 125.9 0.0 1.6e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Phytase PF02333.15 KND90062.1 - 0.00014 21.0 0.0 0.029 13.4 0.0 2.9 3 0 0 3 3 3 2 Phytase ANAPC4_WD40 PF12894.7 KND90063.1 - 0.00016 21.9 0.0 0.83 10.0 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_20 PF00728.22 KND90064.1 - 1e-99 334.3 0.1 1.2e-99 334.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KND90064.1 - 1.1e-26 94.1 0.0 2.2e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KND90064.1 - 9.2e-05 23.2 0.0 0.00019 22.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 3HCDH_RFF PF18321.1 KND90064.1 - 0.11 12.9 0.2 0.87 10.1 0.0 2.3 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain ABC_tran PF00005.27 KND90065.1 - 5.2e-45 153.3 0.0 6.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND90065.1 - 2.9e-30 105.8 29.3 5e-25 88.7 11.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KND90065.1 - 1e-12 48.5 0.8 0.0092 15.8 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND90065.1 - 1e-08 34.9 0.8 0.12 11.8 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND90065.1 - 1.9e-05 24.3 1.8 0.074 12.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KND90065.1 - 2e-05 25.0 1.5 0.061 13.7 0.1 3.1 2 1 1 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.23 KND90065.1 - 2.1e-05 24.6 1.5 0.0064 16.6 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 KND90065.1 - 3.5e-05 24.1 0.1 0.42 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KND90065.1 - 7.4e-05 22.7 2.3 0.078 12.9 0.2 2.8 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 KND90065.1 - 0.00011 22.3 0.4 0.34 11.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 KND90065.1 - 0.0045 16.1 1.4 1.9 7.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.6 KND90065.1 - 0.0055 16.9 0.5 1.7 8.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KND90065.1 - 0.014 14.8 1.3 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 KND90065.1 - 0.016 14.0 0.7 0.45 9.3 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 KND90065.1 - 0.019 15.1 3.8 0.032 14.3 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 KND90065.1 - 0.02 14.4 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 KND90065.1 - 0.048 13.9 0.1 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KND90065.1 - 0.052 13.3 0.1 2.8 7.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 KND90065.1 - 0.061 13.8 1.8 6.2 7.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KND90065.1 - 0.069 12.7 2.0 2.3 7.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KND90065.1 - 0.11 12.2 0.5 5.2 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 KND90065.1 - 0.12 11.9 0.2 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SbcCD_C PF13558.6 KND90065.1 - 0.14 12.4 0.1 36 4.7 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 KND90065.1 - 0.16 11.8 1.7 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Septin PF00735.18 KND90065.1 - 0.18 11.1 0.3 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Septin MeaB PF03308.16 KND90065.1 - 0.43 9.5 2.0 0.53 9.2 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 KND90066.1 - 5.5e-09 36.1 0.0 9.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND90066.1 - 3e-05 24.5 0.0 0.0001 22.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KND90066.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 KND90066.1 - 0.036 13.3 0.1 0.087 12.0 0.1 1.6 2 0 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 KND90066.1 - 0.044 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 KND90066.1 - 0.063 13.8 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KND90066.1 - 0.071 13.5 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND90066.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KND90068.1 - 5e-06 27.1 1.2 0.13 13.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 KND90068.1 - 0.0012 17.6 0.1 0.0071 15.0 0.0 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.11 KND90068.1 - 0.029 14.1 0.1 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split PALB2_WD40 PF16756.5 KND90068.1 - 0.029 13.3 0.2 0.39 9.6 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 KND90069.1 - 4.7e-09 36.7 7.0 0.00057 20.7 0.3 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90069.1 - 3.4e-07 30.5 0.0 0.0003 21.0 0.0 2.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND90069.1 - 0.016 13.9 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Pkinase_fungal PF17667.1 KND90070.1 - 4.5e-128 427.5 0.6 5.5e-128 427.2 0.6 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KND90070.1 - 8.3e-10 38.5 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND90070.1 - 0.0032 17.4 0.0 0.0074 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND90070.1 - 0.0041 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND90070.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MDFI PF15316.6 KND90070.1 - 0.24 11.4 0.4 0.46 10.6 0.4 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Dynamin_N PF00350.23 KND90071.1 - 1.8e-30 106.2 0.0 5.2e-30 104.7 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND90071.1 - 1.2e-14 54.3 0.0 1.2e-13 51.0 0.0 2.3 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KND90071.1 - 2.6e-05 24.3 0.0 7.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KND90071.1 - 0.032 14.8 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AHH PF14412.6 KND90071.1 - 0.04 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DotU PF09850.9 KND90071.1 - 0.046 13.4 2.9 0.16 11.7 0.5 2.6 2 0 0 2 2 2 0 Type VI secretion system protein DotU SKA1 PF07160.12 KND90071.1 - 0.13 12.1 4.8 0.62 9.9 0.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 AAA_16 PF13191.6 KND90071.1 - 0.15 12.4 0.7 0.88 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain CAP_N PF01213.19 KND90071.1 - 2.6 7.5 7.0 0.82 9.1 3.2 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Cyanate_lyase PF02560.14 KND90072.1 - 4e-27 93.8 0.0 7e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 KND90072.1 - 0.0019 18.5 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Crystall PF00030.19 KND90072.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin HTH_3 PF01381.22 KND90072.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 KND90072.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.25 KND90073.1 - 4.4e-22 78.7 0.0 3.1e-12 46.4 0.0 2.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND90073.1 - 0.00021 20.7 0.0 0.051 12.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Hormone_5 PF00184.17 KND90076.1 - 0.16 12.8 7.5 2.9 8.8 2.6 2.2 2 0 0 2 2 2 0 Neurohypophysial hormones, C-terminal Domain Hydrophobin PF01185.18 KND90076.1 - 0.27 11.9 8.0 0.6 10.8 0.4 2.2 1 1 1 2 2 2 0 Fungal hydrophobin Zn_clus PF00172.18 KND90077.1 - 5.6e-07 29.6 7.6 1.1e-06 28.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND90077.1 - 0.00089 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 KND90078.1 - 7.1e-10 40.0 0.0 1.1e-09 39.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND90078.1 - 8.8e-10 38.7 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND90078.1 - 7.4e-06 25.8 0.0 2.1e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.19 KND90078.1 - 0.17 11.2 0.6 4.3 6.6 0.1 2.3 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GFA PF04828.14 KND90079.1 - 4.1e-23 81.5 0.8 5.7e-23 81.1 0.8 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Aminotran_1_2 PF00155.21 KND90080.1 - 9.2e-43 146.8 0.0 1.1e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 KND90080.1 - 0.097 11.3 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Pribosyltran PF00156.27 KND90081.1 - 4.6e-13 49.0 0.6 5.6e-13 48.7 0.6 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KND90081.1 - 0.088 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Zn_clus PF00172.18 KND90083.1 - 1.3e-06 28.4 7.3 2.4e-06 27.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND90083.1 - 0.0077 15.3 0.2 0.013 14.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1283 PF06932.11 KND90085.1 - 0.13 12.4 0.1 12 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) Pkinase PF00069.25 KND90086.1 - 1.7e-59 201.3 0.0 2.8e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90086.1 - 8.2e-35 120.3 0.0 1.3e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND90086.1 - 3.5e-10 39.7 0.0 9.7e-10 38.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KND90086.1 - 0.00013 21.1 0.8 0.00013 21.1 0.8 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KND90086.1 - 0.061 13.2 2.8 0.14 12.0 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ferlin_C PF16165.5 KND90086.1 - 0.22 11.4 1.2 0.5 10.3 1.2 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Kdo PF06293.14 KND90086.1 - 0.25 10.7 2.7 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDUF_B8 PF05821.11 KND90087.1 - 8.2e-07 29.0 1.8 1e-06 28.7 1.3 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 KND90088.1 - 1.8e-66 224.2 0.2 2.8e-66 223.6 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND90088.1 - 3.8e-18 65.9 0.0 2.7e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90088.1 - 1.3e-09 38.3 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 KND90088.1 - 0.00027 21.2 7.5 0.00027 21.2 7.5 2.3 1 1 1 2 2 2 1 HSA DEAD PF00270.29 KND90088.1 - 0.00038 20.3 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KND90088.1 - 0.0038 16.5 0.1 1.7 7.7 0.0 2.5 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AAA_25 PF13481.6 KND90088.1 - 0.3 10.6 2.7 0.4 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Ilm1 PF10311.9 KND90089.1 - 2.5e-66 222.4 0.1 2.8e-66 222.2 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 KND90090.1 - 6.3e-36 121.8 9.2 8.1e-07 28.7 0.1 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KND90090.1 - 0.00026 20.2 0.1 0.0058 15.8 0.0 2.5 1 1 2 3 3 3 1 Squalene-hopene cyclase C-terminal domain CHCH PF06747.13 KND90090.1 - 0.005 16.9 5.0 0.011 15.9 5.0 1.6 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 KND90090.1 - 0.03 14.5 2.2 0.057 13.6 2.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type SQHop_cyclase_N PF13249.6 KND90090.1 - 0.034 13.3 0.6 15 4.6 0.0 3.4 2 1 1 4 4 4 0 Squalene-hopene cyclase N-terminal domain Sulfotransfer_4 PF17784.1 KND90091.1 - 2.6e-64 217.0 0.1 3.2e-64 216.7 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 KND90091.1 - 2.4e-06 28.1 0.4 0.00015 22.3 0.1 2.6 2 1 0 2 2 2 1 Sulfotransferase family MFS_1 PF07690.16 KND90093.1 - 2.1e-09 36.8 30.9 2.1e-09 36.8 30.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3974 PF13120.6 KND90093.1 - 0.21 11.7 0.5 0.8 9.8 0.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) Aa_trans PF01490.18 KND90094.1 - 1.2e-43 149.4 29.5 1.4e-43 149.2 29.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5079 PF16882.5 KND90094.1 - 0.055 13.3 1.3 0.19 11.5 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) MOSC PF03473.17 KND90095.1 - 2e-37 128.2 0.0 3.3e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KND90095.1 - 8.7e-22 77.3 0.0 2.2e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KND90095.1 - 1.5e-16 60.3 0.0 4.2e-16 58.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_18 PF00704.28 KND90096.1 - 4.9e-73 246.6 3.8 7.4e-73 246.0 3.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HAD PF12710.7 KND90097.1 - 1e-11 45.6 0.2 3.2e-11 44.0 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND90097.1 - 0.0012 19.1 0.1 0.0057 17.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND90097.1 - 0.0035 17.4 0.2 1.4 8.9 0.1 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KND90097.1 - 0.0057 16.1 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase TFIIF_beta_N PF17683.1 KND90098.1 - 7.3e-30 104.4 0.0 1.3e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KND90098.1 - 2.1e-28 98.2 0.4 4.1e-28 97.3 0.4 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF4658 PF15555.6 KND90098.1 - 0.14 12.2 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Glyco_hydro_15 PF00723.21 KND90099.1 - 1.6e-51 175.5 0.0 6.2e-50 170.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 RRM_1 PF00076.22 KND90101.1 - 3e-16 59.0 0.0 5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 KND90101.1 - 0.0048 17.2 0.2 0.02 15.2 0.0 2.2 2 0 0 2 2 2 1 Cytotoxic TPT PF03151.16 KND90102.1 - 7.8e-20 71.4 13.5 1.1e-19 70.9 13.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KND90102.1 - 5.2e-05 23.4 36.5 0.0058 16.8 17.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KND90102.1 - 0.0034 16.7 14.4 0.0034 16.7 14.4 1.7 2 0 0 2 2 2 1 UAA transporter family FAM176 PF14851.6 KND90102.1 - 0.32 10.7 4.5 17 5.0 0.0 2.4 2 0 0 2 2 2 0 FAM176 family DUF2681 PF10883.8 KND90102.1 - 0.71 10.3 3.2 17 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) GPI-anchored PF10342.9 KND90103.1 - 0.024 15.4 0.0 0.024 15.4 0.0 2.2 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family L6_membrane PF05805.12 KND90103.1 - 0.048 13.2 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 L6 membrane protein FAM220 PF15487.6 KND90103.1 - 1.5 8.4 5.6 2.2 7.8 5.6 1.2 1 0 0 1 1 1 0 FAM220 family CDC27 PF09507.10 KND90103.1 - 3.4 6.9 16.6 4.8 6.5 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Menin PF05053.13 KND90103.1 - 4.4 5.5 8.6 5.6 5.2 8.6 1.3 1 0 0 1 1 1 0 Menin SWI-SNF_Ssr4 PF08549.10 KND90104.1 - 9.5e-275 913.8 7.5 3e-274 912.1 7.5 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 KND90104.1 - 3.7e-127 423.7 0.0 5.2e-127 423.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KND90104.1 - 2.2e-50 170.9 0.0 4.7e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KND90104.1 - 0.048 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Nas2_N PF18265.1 KND90105.1 - 4.4e-29 100.2 0.0 6.5e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KND90105.1 - 4.4e-08 32.9 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KND90105.1 - 3.8e-06 27.3 0.0 6.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 KND90105.1 - 2.5e-05 24.5 0.0 4.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 KND90105.1 - 0.00095 19.5 0.0 0.0041 17.4 0.0 1.9 1 1 1 2 2 2 1 PDZ domain PWI PF01480.17 KND90106.1 - 2.1e-29 101.6 0.1 3.1e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 PWI domain G-patch PF01585.23 KND90107.1 - 9.8e-06 25.4 0.0 4.1e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 G-patch domain Hydrolase_6 PF13344.6 KND90107.1 - 0.053 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Macoilin PF09726.9 KND90107.1 - 0.46 9.0 27.8 0.62 8.6 27.8 1.2 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 KND90107.1 - 6.4 3.8 28.5 8.3 3.4 28.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3546 PF12066.8 KND90108.1 - 8.1e-34 116.1 3.6 8.1e-34 116.1 3.6 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 KND90108.1 - 1.4e-12 47.2 0.2 5.3e-12 45.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 KND90108.1 - 6.1e-06 26.8 14.8 3.4e-05 24.3 14.0 2.7 2 1 0 2 2 2 1 Arsenite-resistance protein 2 tRNA-synt_2d PF01409.20 KND90109.1 - 1.7e-82 276.6 0.0 2.3e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KND90109.1 - 2.7e-16 59.6 2.1 3.9e-16 59.1 0.7 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 KND90109.1 - 5.4e-07 29.5 2.4 1.8e-06 27.8 2.4 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 KND90109.1 - 5.9e-07 29.2 0.0 0.0067 15.9 0.0 3.1 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KND90109.1 - 0.00012 21.2 0.3 0.0022 17.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1938 PF09153.10 KND90109.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) RTC_insert PF05189.13 KND90111.1 - 7.1e-30 103.6 0.1 1.4e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KND90111.1 - 5.6e-29 100.9 0.3 7.1e-29 100.6 0.3 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase DUF1746 PF08508.10 KND90112.1 - 2.2e-40 137.6 2.4 3.1e-40 137.1 2.4 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF1509 PF07420.11 KND90112.1 - 0.02 13.9 0.3 0.028 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PPR_2 PF13041.6 KND90113.1 - 8.8e-12 45.0 0.1 5e-07 29.8 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 KND90113.1 - 1.5e-06 28.0 0.8 0.4 11.0 0.0 4.1 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 KND90113.1 - 2.3e-05 24.4 0.0 0.0072 16.4 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_16 PF13432.6 KND90113.1 - 0.00016 22.3 0.1 0.14 12.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_1 PF12854.7 KND90113.1 - 0.00035 20.2 0.3 4.5 7.1 0.1 4.3 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.6 KND90113.1 - 0.0034 18.1 0.1 0.67 10.9 0.0 4.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND90113.1 - 0.011 16.2 0.1 1.2 9.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND90113.1 - 0.017 15.1 0.1 24 5.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND90113.1 - 0.023 15.3 0.9 2.9 8.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 KND90113.1 - 0.032 14.0 1.2 18 5.0 0.0 3.8 4 0 0 4 4 4 0 26S proteasome subunit RPN7 DrrA_P4M PF14860.6 KND90113.1 - 0.46 10.3 1.7 3.5 7.5 0.1 2.7 2 1 1 3 3 3 0 DrrA phosphatidylinositol 4-phosphate binding domain P53_TAD PF08563.11 KND90113.1 - 1.3 8.6 5.2 0.9 9.1 0.1 2.6 2 0 0 2 2 2 0 P53 transactivation motif Peptidase_S9 PF00326.21 KND90114.1 - 5.7e-49 166.5 0.7 4.9e-47 160.2 0.7 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family NuA4 PF09340.10 KND90114.1 - 9e-23 80.0 0.2 2.6e-22 78.5 0.2 1.9 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Bromo_TP PF07524.13 KND90114.1 - 1.1e-10 41.4 0.1 2.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated HTH_Tnp_Tc5 PF03221.16 KND90114.1 - 2.8e-08 33.7 0.2 9e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PD40 PF07676.12 KND90114.1 - 2.2e-05 24.2 0.0 0.00053 19.8 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TFIID-31kDa PF02291.15 KND90114.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Med9 PF07544.13 KND90114.1 - 0.51 10.5 1.8 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Clr5 PF14420.6 KND90115.1 - 7e-19 67.8 1.9 1.7e-18 66.6 1.9 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 KND90115.1 - 0.00013 22.2 2.9 0.00013 22.2 2.9 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND90115.1 - 0.00067 19.5 0.2 0.42 10.8 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 KND90115.1 - 0.0021 17.9 8.4 0.16 11.9 1.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF2852 PF11014.8 KND90115.1 - 0.023 14.9 0.7 0.023 14.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) TPR_14 PF13428.6 KND90115.1 - 1.2 10.1 16.3 3.9 8.5 1.5 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DnaJ PF00226.31 KND90116.1 - 7.1e-08 32.5 0.1 1.2e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 KND90116.1 - 0.0062 16.6 1.8 0.011 15.8 1.8 1.5 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.13 KND90116.1 - 0.043 14.1 1.1 0.063 13.6 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LSM PF01423.22 KND90117.1 - 2e-17 62.6 0.0 2.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 KND90118.1 - 1.8e-22 79.3 0.0 2.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KND90118.1 - 2.6e-20 72.5 0.0 8.2e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 CorA PF01544.18 KND90120.1 - 1.2e-11 44.4 3.4 9.5e-11 41.5 0.2 2.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein APG6_N PF17675.1 KND90120.1 - 0.039 14.5 0.1 0.039 14.5 0.1 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4231 PF14015.6 KND90120.1 - 0.21 12.1 0.4 0.57 10.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PITH PF06201.13 KND90122.1 - 8.3e-35 120.2 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KND90122.1 - 1.9e-27 95.2 0.0 3.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KND90122.1 - 1.4e-08 35.0 0.0 1.5e-06 28.4 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KND90122.1 - 4.1e-06 27.2 0.0 1.2e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 KND90122.1 - 9.1e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KND90122.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND90122.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 KND90122.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KND90122.1 - 0.093 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like PI31_Prot_N PF11566.8 KND90122.1 - 0.17 11.7 0.0 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal Zn_clus PF00172.18 KND90123.1 - 0.00065 19.8 11.2 0.0014 18.7 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMYLE_N PF18615.1 KND90123.1 - 0.13 11.8 6.4 0.26 10.8 6.4 1.5 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PGA2 PF07543.12 KND90123.1 - 0.49 10.4 4.0 0.95 9.4 4.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Menin PF05053.13 KND90123.1 - 1.9 6.7 8.5 3.1 6.0 8.5 1.3 1 0 0 1 1 1 0 Menin RhoGAP PF00620.27 KND90124.1 - 1.6e-43 148.1 0.5 7.4e-43 146.0 0.2 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 KND90124.1 - 7.7e-12 45.7 0.0 1.7e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Med21 PF11221.8 KND90124.1 - 0.013 15.8 0.6 0.013 15.8 0.6 3.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex CREPT PF16566.5 KND90124.1 - 0.025 14.7 0.6 0.061 13.5 0.6 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour CENP-K PF11802.8 KND90126.1 - 6.2e-10 39.1 1.2 0.00037 20.2 6.3 2.5 2 1 0 2 2 2 2 Centromere-associated protein K DUF724 PF05266.14 KND90126.1 - 0.079 12.8 7.7 0.65 9.8 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KND90126.1 - 0.23 11.6 7.8 0.3 11.2 7.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CDC37_N PF03234.14 KND90126.1 - 1.3 9.9 7.3 0.5 11.3 3.2 2.3 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Atg14 PF10186.9 KND90126.1 - 2 7.4 8.8 0.63 9.1 4.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KND90126.1 - 2.4 7.0 13.2 1.7 7.5 6.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Cnn_1N PF07989.11 KND90126.1 - 2.7 8.2 15.9 3.2 8.0 0.3 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 MRP-S26 PF14943.6 KND90126.1 - 4.7 7.1 14.3 0.94 9.4 8.7 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 LUC7 PF03194.15 KND90126.1 - 5.7 6.5 12.0 11 5.5 7.3 2.2 1 1 1 2 2 2 0 LUC7 N_terminus DUF1349 PF07081.11 KND90127.1 - 9e-24 84.2 0.1 1e-23 84.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ASCH PF04266.14 KND90127.1 - 0.0051 17.4 0.0 0.0079 16.8 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Peptidase_S9 PF00326.21 KND90128.1 - 4.6e-24 85.1 0.0 2e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family ABM PF03992.16 KND90129.1 - 4e-06 26.8 0.1 0.0003 20.8 0.1 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Exo_endo_phos PF03372.23 KND90130.1 - 2.4e-15 56.7 0.3 3.8e-15 56.0 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spo7 PF03907.13 KND90130.1 - 0.061 12.8 0.6 0.1 12.1 0.6 1.2 1 0 0 1 1 1 0 Spo7-like protein SLATT_5 PF18160.1 KND90130.1 - 0.12 11.7 0.2 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 KH_1 PF00013.29 KND90132.1 - 3.5e-40 135.7 2.7 1.2e-17 63.5 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KND90132.1 - 4.9e-13 48.7 3.3 0.002 17.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KND90132.1 - 1.6e-07 31.1 0.4 0.2 11.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KND90132.1 - 4.5e-05 23.5 6.8 0.2 11.8 0.2 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KND90132.1 - 0.00042 20.3 0.0 0.26 11.3 0.0 2.9 3 0 0 3 3 3 2 KH-like RNA-binding domain BTB PF00651.31 KND90134.1 - 1.3e-07 31.8 0.0 4.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain EPO_TPO PF00758.18 KND90134.1 - 0.00046 20.3 0.1 0.0007 19.7 0.1 1.2 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin Proteasome PF00227.26 KND90135.1 - 4.5e-32 111.1 0.0 6.2e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Integrase_Zn PF02022.19 KND90135.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain HMG_box_2 PF09011.10 KND90136.1 - 8.1e-08 32.8 0.6 1.3e-05 25.6 0.1 2.8 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 KND90136.1 - 7.3e-06 26.3 0.2 7.3e-06 26.3 0.2 2.9 3 2 0 3 3 3 1 HMG (high mobility group) box ThiD2 PF17792.1 KND90136.1 - 0.71 10.3 3.7 1.8 9.0 0.0 2.8 3 0 0 3 3 3 0 ThiD2 family AAA PF00004.29 KND90137.1 - 1.9e-42 144.8 0.0 3.4e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KND90137.1 - 3.6e-11 42.8 0.1 4.2e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KND90137.1 - 4.2e-10 39.3 0.0 8.1e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KND90137.1 - 1.1e-07 32.4 0.0 6.7e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KND90137.1 - 1.9e-06 27.9 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND90137.1 - 3e-06 27.4 0.0 9.2e-06 25.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KND90137.1 - 7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KND90137.1 - 0.00023 21.4 0.1 0.006 16.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KND90137.1 - 0.00032 20.0 0.0 0.00076 18.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KND90137.1 - 0.00051 20.6 0.1 0.0027 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KND90137.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 KND90137.1 - 0.0024 17.2 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 KND90137.1 - 0.0031 17.5 0.1 0.0097 15.9 0.0 1.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KND90137.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KND90137.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KND90137.1 - 0.0053 16.5 0.2 0.013 15.3 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KND90137.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 KND90137.1 - 0.0065 16.5 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KND90137.1 - 0.0084 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.6 KND90137.1 - 0.01 15.6 0.7 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 KND90137.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND90137.1 - 0.02 14.6 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 KND90137.1 - 0.029 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KND90137.1 - 0.038 13.4 0.7 0.13 11.5 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 KND90137.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KND90137.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 KND90137.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein eIF-1a PF01176.19 KND90137.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_28 PF13521.6 KND90137.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KND90137.1 - 0.096 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KND90137.1 - 0.097 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KND90137.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 KND90137.1 - 0.3 11.6 3.1 33 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 KND90137.1 - 0.66 9.8 3.1 6.7 6.6 1.1 2.8 2 0 0 2 2 2 0 Septum formation initiator DUF4200 PF13863.6 KND90137.1 - 1.2 9.6 6.8 0.26 11.7 3.1 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) SIS PF01380.22 KND90138.1 - 9.7e-59 196.9 0.1 8.3e-31 106.5 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KND90138.1 - 3.8e-17 62.7 0.0 7.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KND90138.1 - 1.5e-09 37.8 0.0 3.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KND90138.1 - 0.00026 20.0 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UCR_UQCRX_QCR9 PF05365.12 KND90139.1 - 1e-25 89.4 2.4 1.2e-25 89.2 2.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 KND90140.1 - 1.7e-14 53.4 3.1 3.3e-14 52.5 3.1 1.5 1 0 0 1 1 1 1 Mago binding CRC_subunit PF08624.10 KND90142.1 - 3.7e-53 179.6 0.0 7.5e-53 178.6 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SDA1 PF05285.12 KND90142.1 - 0.14 11.6 3.8 0.18 11.2 3.8 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 KND90142.1 - 4.1 5.6 6.0 5.8 5.1 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KND90142.1 - 5.7 5.0 7.3 8.1 4.5 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-UBR PF02207.20 KND90143.1 - 1.6e-17 63.4 16.4 1.6e-17 63.4 16.4 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KND90143.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CAP_N PF01213.19 KND90143.1 - 0.69 9.3 3.1 1.3 8.5 3.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BUD22 PF09073.10 KND90143.1 - 0.84 8.9 16.8 0.18 11.1 10.7 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 KND90143.1 - 4.2 5.5 22.0 0.73 8.0 12.3 2.3 2 0 0 2 2 2 0 Nop14-like family Nefa_Nip30_N PF10187.9 KND90144.1 - 1.1e-30 106.0 8.3 1.1e-30 106.0 8.3 2.1 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Caldesmon PF02029.15 KND90144.1 - 0.015 14.1 25.5 0.019 13.8 25.5 1.0 1 0 0 1 1 1 0 Caldesmon Cyclin PF08613.11 KND90145.1 - 1.2e-08 35.5 0.0 2.6e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin IL11 PF07400.11 KND90145.1 - 0.058 13.0 1.3 0.089 12.4 1.3 1.2 1 0 0 1 1 1 0 Interleukin 11 ADH_zinc_N PF00107.26 KND90146.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND90146.1 - 4.5e-05 23.3 0.0 9.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 KND90147.1 - 8.3e-09 35.4 11.6 1.5e-08 34.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 KND90148.1 - 8.3e-139 462.4 0.0 9.4e-139 462.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND90148.1 - 2.6e-07 29.9 1.0 9.6e-07 28.1 0.2 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KND90148.1 - 7.1e-07 28.7 0.1 1.2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KND90148.1 - 0.00094 18.6 0.4 0.0017 17.7 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 KND90148.1 - 0.01 14.7 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein 2-Hacid_dh PF00389.30 KND90148.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F-box PF00646.33 KND90149.1 - 0.017 15.0 0.6 0.094 12.6 0.3 2.5 3 0 0 3 3 3 0 F-box domain Miga PF10265.9 KND90151.1 - 0.039 12.9 0.2 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitoguardin SKG6 PF08693.10 KND90151.1 - 0.063 12.7 0.9 0.13 11.7 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KND90151.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 KND90151.1 - 0.21 11.9 0.4 0.89 9.9 0.0 2.1 3 0 0 3 3 3 0 Orf78 (ac78) TMEM108 PF15759.5 KND90151.1 - 1.6 7.7 15.0 4.1 6.3 15.0 1.7 1 1 0 1 1 1 0 TMEM108 family HLH PF00010.26 KND90152.1 - 2.9e-12 46.4 1.4 5.4e-12 45.5 0.6 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 KND90152.1 - 0.0011 18.6 0.6 0.0023 17.6 0.6 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator DUF4776 PF16003.5 KND90152.1 - 0.052 12.6 0.3 0.075 12.0 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TPR_2 PF07719.17 KND90153.1 - 5.7e-22 76.0 3.9 2.9e-06 27.0 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND90153.1 - 3.6e-21 74.0 2.4 2.1e-06 27.3 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KND90153.1 - 9.2e-17 60.3 4.6 2.5e-05 24.7 0.0 6.2 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KND90153.1 - 2.9e-16 59.8 3.3 7.3e-06 26.5 0.7 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND90153.1 - 8.2e-16 57.4 1.9 7.3e-07 28.8 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 KND90153.1 - 3.7e-13 48.9 4.7 0.037 14.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KND90153.1 - 1.7e-12 47.6 15.2 0.00039 20.9 0.2 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND90153.1 - 7.7e-11 41.3 3.0 0.0002 21.3 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND90153.1 - 9.7e-11 40.9 0.9 0.0047 16.9 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KND90153.1 - 1.5e-07 31.6 0.5 19 6.2 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND90153.1 - 1.6e-07 31.3 0.8 0.017 15.3 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND90153.1 - 4.4e-07 30.1 6.6 0.012 15.9 0.8 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KND90153.1 - 6.2e-07 29.7 6.9 0.0099 16.2 0.1 4.8 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 KND90153.1 - 0.00012 21.4 6.6 0.063 12.5 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND90153.1 - 0.0019 18.4 5.0 0.53 10.5 0.3 3.3 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KND90153.1 - 0.018 15.0 0.0 2.4 8.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1641 PF07849.11 KND90153.1 - 0.088 12.7 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_10 PF13374.6 KND90153.1 - 1.3 8.9 8.8 0.5 10.3 0.2 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Brix PF04427.18 KND90154.1 - 6.1e-45 153.7 0.0 8.1e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Fungal_trans_2 PF11951.8 KND90155.1 - 8.7e-06 24.8 0.2 1.7e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90155.1 - 1.2 9.3 14.6 0.38 10.9 2.3 2.6 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC_WH_C PF18137.1 KND90156.1 - 7.3e-27 94.2 0.0 1.1e-24 87.0 0.0 2.6 1 1 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 KND90156.1 - 3.7e-16 59.2 1.2 2.8e-14 53.0 0.3 2.8 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus PWWP PF00855.17 KND90157.1 - 1.1e-15 57.8 0.1 1.1e-15 57.8 0.1 2.4 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 KND90157.1 - 0.00037 20.5 0.3 0.00079 19.4 0.3 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CPSase_L_D2 PF02786.17 KND90158.1 - 3e-109 363.4 0.0 2.2e-84 282.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KND90158.1 - 3.7e-40 137.1 0.3 8.8e-40 135.8 0.3 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KND90158.1 - 6.6e-20 71.4 0.2 1.5e-08 34.4 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KND90158.1 - 1.7e-17 63.6 0.5 4e-08 33.0 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KND90158.1 - 2.3e-10 40.3 0.0 0.0011 18.8 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KND90158.1 - 6.1e-06 26.4 0.4 0.019 15.0 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 KND90158.1 - 6.1e-05 22.9 0.4 0.37 10.5 0.0 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KND90158.1 - 6.4e-05 22.6 0.0 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KND90158.1 - 8.1e-05 22.2 0.0 0.044 13.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.6 KND90158.1 - 0.0024 17.5 0.0 0.033 13.8 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain NPL4 PF05021.15 KND90159.1 - 6.9e-137 455.9 0.0 8.5e-137 455.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KND90159.1 - 7.8e-65 217.4 0.0 1.2e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KND90159.1 - 0.0024 18.3 0.0 0.009 16.5 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KND90160.1 - 3.3e-78 261.4 0.1 4e-78 261.1 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 HpcH_HpaI PF03328.14 KND90162.1 - 5.1e-32 110.8 0.0 6.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.9 KND90162.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) SHS2_Rpb7-N PF03876.17 KND90163.1 - 6.7e-15 55.2 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KND90163.1 - 4.6e-13 49.3 0.0 8.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 KND90164.1 - 3.4e-29 100.8 0.7 7.2e-29 99.7 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TMEM169 PF15052.6 KND90164.1 - 0.043 13.9 3.7 0.069 13.3 3.7 1.4 1 0 0 1 1 1 0 TMEM169 protein family Formyl_trans_N PF00551.19 KND90165.1 - 2e-30 105.9 0.0 2.6e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase DUF4690 PF15756.5 KND90166.1 - 0.00088 19.8 1.9 0.00088 19.8 1.9 1.8 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Mucin15 PF15672.5 KND90166.1 - 0.13 11.8 2.8 0.22 11.0 2.8 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Ribosomal_L6 PF00347.23 KND90167.1 - 6.4e-28 97.2 7.2 1.9e-13 50.9 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 HSP20 PF00011.21 KND90168.1 - 1.9e-16 60.1 0.1 3.8e-12 46.2 0.1 2.5 2 0 0 2 2 2 2 Hsp20/alpha crystallin family YTH PF04146.15 KND90168.1 - 5.2e-13 49.3 1.4 5.7e-13 49.1 0.1 1.8 2 0 0 2 2 2 1 YT521-B-like domain ArsA_HSP20 PF17886.1 KND90168.1 - 0.015 14.8 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 HSP20-like domain found in ArsA RRM_1 PF00076.22 KND90168.1 - 0.05 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 KND90169.1 - 9e-19 67.7 0.1 2.1e-18 66.5 0.1 1.6 1 1 0 1 1 1 1 Proteasome subunit Vps26 PF03643.15 KND90170.1 - 8.1e-130 431.7 0.7 9.2e-130 431.6 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KND90170.1 - 0.00013 22.1 0.8 0.091 12.8 0.7 3.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KND90170.1 - 0.019 15.4 0.0 0.17 12.3 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 KND90170.1 - 0.057 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Rad51 PF08423.11 KND90171.1 - 3e-127 423.2 0.0 3.7e-127 422.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KND90171.1 - 6.4e-09 35.7 0.0 9.2e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KND90171.1 - 4.7e-08 32.8 0.0 7.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KND90171.1 - 0.00025 20.5 0.0 0.00049 19.5 0.0 1.6 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 KND90171.1 - 0.00048 20.7 0.9 0.00092 19.8 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 KND90171.1 - 0.0068 15.8 0.3 0.041 13.2 0.0 2.2 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 KND90171.1 - 0.22 11.6 0.5 0.63 10.1 0.1 1.9 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain DUF5520 PF17658.1 KND90172.1 - 0.029 13.5 2.3 0.055 12.6 2.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5520) GCIP PF13324.6 KND90172.1 - 0.3 10.7 3.6 0.54 9.8 3.6 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 KND90172.1 - 0.41 9.9 6.3 0.98 8.7 6.3 1.6 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 KND90172.1 - 2 6.6 6.7 4.2 5.5 6.7 1.5 1 0 0 1 1 1 0 CDC45-like protein PI3_PI4_kinase PF00454.27 KND90174.1 - 2.9e-38 132.1 0.1 5.9e-36 124.5 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KND90174.1 - 2.3e-23 82.5 0.0 6e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cation_efflux PF01545.21 KND90175.1 - 2.7e-20 72.9 11.3 3.6e-20 72.5 11.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KND90175.1 - 8.3e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Lum_binding PF00677.17 KND90176.1 - 1.3e-45 153.2 0.4 5.9e-23 80.7 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 KND90177.1 - 5.8e-25 88.3 0.1 9.8e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KND90177.1 - 0.00041 20.7 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KND90177.1 - 0.0072 16.9 0.0 0.04 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain T2SSK PF03934.13 KND90177.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K PGM_PMM_I PF02878.16 KND90178.1 - 3.1e-17 62.6 0.2 7.3e-08 32.2 0.0 3.1 1 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KND90178.1 - 1.7e-10 40.9 0.3 6.8e-10 39.0 0.3 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KND90178.1 - 0.0039 17.4 0.2 0.022 14.9 0.2 2.3 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KND90178.1 - 0.015 15.9 0.5 0.33 11.6 0.5 2.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Ribosomal_S8e PF01201.22 KND90181.1 - 3e-45 153.7 6.7 8e-45 152.4 6.7 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.21 KND90182.1 - 1.7e-13 50.7 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 KND90183.1 - 4.9e-46 157.2 0.0 8.1e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90183.1 - 4.6e-20 72.0 0.0 7.1e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND90183.1 - 0.00097 19.1 0.1 0.46 10.4 0.0 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND90183.1 - 0.023 14.0 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like HLH PF00010.26 KND90184.1 - 7.1e-13 48.3 0.3 1.2e-12 47.6 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_12 PF13424.6 KND90185.1 - 1.8e-16 60.1 0.8 1.5e-08 34.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND90185.1 - 1.1e-13 51.6 0.4 2.1e-05 25.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND90185.1 - 6.2e-11 41.5 4.2 2e-05 24.3 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND90185.1 - 9.7e-11 42.0 3.7 0.023 15.2 0.0 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND90185.1 - 1.6e-09 37.2 0.1 3.1e-05 23.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND90185.1 - 7.1e-09 35.8 6.2 0.77 10.7 0.1 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KND90185.1 - 8.5e-09 34.8 0.6 0.00018 21.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND90185.1 - 6.5e-08 32.1 0.0 0.00017 21.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KND90185.1 - 1.8e-07 30.9 1.0 0.008 15.6 0.0 2.3 1 1 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 KND90185.1 - 7.2e-06 25.7 1.6 0.019 14.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND90185.1 - 0.00051 20.2 0.0 2.4 8.5 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 KND90185.1 - 0.00083 19.0 2.0 2.1 8.0 0.1 3.3 3 0 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 KND90185.1 - 0.0014 18.7 1.0 4.6 7.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 KND90185.1 - 0.0016 18.8 0.4 0.25 12.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND90185.1 - 0.0029 18.1 2.9 2.4 9.0 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KND90185.1 - 0.063 13.0 0.0 1.5 8.6 0.0 2.9 4 0 0 4 4 4 0 TPR repeat RWD PF05773.22 KND90186.1 - 3.6e-24 85.3 0.2 6.2e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KND90186.1 - 0.0003 21.2 6.1 0.0006 20.3 5.5 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF2852 PF11014.8 KND90186.1 - 0.0083 16.3 1.5 0.013 15.6 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) PP2C PF00481.21 KND90187.1 - 5.3e-57 193.4 0.0 8.7e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 KND90187.1 - 3.2e-42 141.8 54.0 3.6e-05 24.0 0.5 11.4 10 1 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND90187.1 - 1.1e-41 140.4 48.5 2.2e-08 33.8 0.3 9.5 4 3 6 10 10 10 10 Leucine rich repeat Guanylate_cyc PF00211.20 KND90187.1 - 1.9e-32 112.4 0.0 1e-31 110.0 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 KND90187.1 - 1.6e-24 85.4 2.8 3.7e-24 84.2 2.8 1.7 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 KND90187.1 - 2.7e-07 30.2 41.8 3.2 8.6 0.2 15.4 18 2 0 18 18 18 2 Leucine Rich Repeat LRR_9 PF14580.6 KND90187.1 - 0.0045 16.5 13.4 1.2 8.6 0.6 4.3 3 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 KND90187.1 - 0.0079 16.2 37.2 3.4 8.0 0.3 11.7 13 0 0 13 13 13 2 Leucine Rich repeat Glyco_transf_22 PF03901.17 KND90188.1 - 6.2e-41 141.0 13.5 8.1e-41 140.6 13.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family O_anti_polymase PF01901.16 KND90188.1 - 0.016 14.5 1.6 0.016 14.5 1.6 1.7 2 0 0 2 2 2 0 Putative O-antigen polymerase DUF441 PF04284.13 KND90188.1 - 1.2 9.2 7.2 0.14 12.2 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF441) Alpha-amylase PF00128.24 KND90189.1 - 4.2e-114 381.6 0.0 7.3e-114 380.8 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KND90189.1 - 2.2e-07 30.9 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DUF3459 PF11941.8 KND90189.1 - 0.0033 17.7 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 KND90189.1 - 0.0045 17.4 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.6 KND90189.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain RTC4 PF14474.6 KND90190.1 - 7.3e-30 103.6 0.0 1.5e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain ThiS PF02597.20 KND90191.1 - 4.7e-09 36.8 0.0 5.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family Dynamitin PF04912.14 KND90192.1 - 3.4e-115 385.5 9.8 4.1e-115 385.2 9.8 1.1 1 0 0 1 1 1 1 Dynamitin DUF2046 PF09755.9 KND90192.1 - 0.021 14.1 6.0 1.1 8.4 1.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) BAAT_C PF08840.11 KND90192.1 - 0.033 14.1 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FH2 PF02181.23 KND90192.1 - 0.035 13.2 4.0 2.4 7.2 0.1 3.1 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF2408 PF10303.9 KND90192.1 - 0.037 14.6 3.3 1.6 9.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Fzo_mitofusin PF04799.13 KND90192.1 - 0.039 13.5 4.3 0.57 9.7 0.1 3.1 3 0 0 3 3 3 0 fzo-like conserved region SOGA PF11365.8 KND90192.1 - 0.041 15.0 8.1 0.13 13.4 0.2 3.6 3 1 0 3 3 3 0 Protein SOGA STAT_alpha PF01017.20 KND90192.1 - 0.045 13.7 2.1 0.11 12.4 0.6 2.2 2 0 0 2 2 2 0 STAT protein, all-alpha domain Flagellin_N PF00669.20 KND90192.1 - 0.048 13.8 0.6 0.048 13.8 0.6 3.4 3 1 1 4 4 4 0 Bacterial flagellin N-terminal helical region BLOC1_2 PF10046.9 KND90192.1 - 0.049 13.9 5.3 7.8 6.9 0.2 4.0 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 KND90192.1 - 0.071 12.9 12.8 0.096 12.5 0.4 3.4 3 0 0 3 3 3 0 Phage minor structural protein GP20 Spore_III_AB PF09548.10 KND90192.1 - 0.15 12.1 0.2 0.15 12.1 0.2 3.0 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Fib_alpha PF08702.10 KND90192.1 - 0.19 11.9 6.8 9 6.5 0.5 3.6 2 2 1 4 4 4 0 Fibrinogen alpha/beta chain family PIEZO PF15917.5 KND90192.1 - 0.24 10.8 2.2 5.9 6.3 0.0 2.7 3 0 0 3 3 3 0 Piezo Prefoldin_2 PF01920.20 KND90192.1 - 0.32 11.0 8.0 3.3 7.7 0.4 3.6 3 0 0 3 3 3 0 Prefoldin subunit DUF3450 PF11932.8 KND90192.1 - 0.34 10.2 12.2 1.4 8.2 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 KND90192.1 - 0.41 9.6 5.9 0.93 8.4 0.1 3.1 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 KND90192.1 - 0.44 10.8 4.5 5.4 7.3 0.2 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF745 PF05335.13 KND90192.1 - 0.56 9.9 9.7 1.4 8.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Matrilin_ccoil PF10393.9 KND90192.1 - 0.57 10.1 1.9 14 5.7 0.2 3.1 3 0 0 3 3 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 KND90192.1 - 0.62 10.1 4.8 15 5.7 0.7 3.0 3 1 1 5 5 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.19 KND90192.1 - 0.68 9.6 7.7 3.9 7.1 0.5 3.5 2 1 1 3 3 3 0 GrpE SKA1 PF07160.12 KND90192.1 - 0.74 9.6 4.1 2.3 8.0 0.1 2.6 3 0 0 3 3 2 0 Spindle and kinetochore-associated protein 1 DHR10 PF18595.1 KND90192.1 - 0.84 9.7 18.0 3.8 7.6 0.9 3.9 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain PI3K_P85_iSH2 PF16454.5 KND90192.1 - 0.86 9.2 5.6 7.2 6.2 0.1 3.0 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ADIP PF11559.8 KND90192.1 - 1.4 9.0 12.1 3 7.9 0.5 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 KND90192.1 - 1.4 9.6 5.5 6.3 7.5 0.1 3.2 3 0 0 3 3 3 0 Initiation control protein YabA FliD_N PF02465.18 KND90192.1 - 1.9 9.3 8.3 1.8 9.3 0.9 3.1 3 1 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus Jnk-SapK_ap_N PF09744.9 KND90192.1 - 2 8.6 9.6 3.2 8.0 0.1 3.3 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 COG2 PF06148.11 KND90192.1 - 2.1 8.5 6.1 56 3.8 0.2 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 KND90192.1 - 2.2 9.0 10.4 18 6.1 0.3 4.1 3 0 0 3 3 3 0 SlyX DUF1192 PF06698.11 KND90192.1 - 3.2 7.9 14.0 0.48 10.5 2.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Laminin_II PF06009.12 KND90192.1 - 3.3 7.7 10.4 1.9 8.5 0.3 3.9 2 1 2 4 4 4 0 Laminin Domain II MRPL52 PF18699.1 KND90192.1 - 4 7.7 5.5 5.3 7.3 0.0 3.0 3 0 0 3 3 2 0 Mitoribosomal protein mL52 MIP-T3_C PF17749.1 KND90192.1 - 4 7.4 10.6 0.3 11.0 0.9 3.1 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region HWE_HK PF07536.14 KND90192.1 - 7.8 7.3 8.2 0.8 10.4 0.5 3.3 4 1 0 4 4 2 0 HWE histidine kinase GTP-bdg_M PF16360.5 KND90192.1 - 9.3 6.9 9.5 0.49 11.0 0.9 3.1 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region GFA PF04828.14 KND90194.1 - 1e-19 70.6 0.4 7.4e-09 35.8 0.0 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Dus PF01207.17 KND90195.1 - 2e-27 96.1 0.4 2.6e-24 85.9 0.0 3.0 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) IBR PF01485.21 KND90195.1 - 6.2e-05 23.1 35.7 0.00026 21.2 12.6 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain AsiA PF09010.10 KND90195.1 - 0.079 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A FAA_hydrolase PF01557.18 KND90196.1 - 1.2e-63 214.7 0.0 1.5e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 14-3-3 PF00244.20 KND90197.1 - 1.2e-107 358.5 2.0 1.4e-107 358.3 2.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KND90197.1 - 0.01 14.2 0.6 0.016 13.6 0.6 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ima1_N PF09779.9 KND90197.1 - 0.13 13.1 0.4 1.6 9.6 0.0 2.6 3 1 0 3 3 3 0 Ima1 N-terminal domain MitMem_reg PF13012.6 KND90197.1 - 0.2 12.1 1.2 1 9.8 0.3 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Syja_N PF02383.18 KND90199.1 - 2.8e-71 240.4 0.0 4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KND90199.1 - 6e-10 39.0 0.1 1.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_14 PF13428.6 KND90200.1 - 7.5e-09 35.7 2.4 0.74 10.8 0.0 7.0 4 2 2 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 KND90200.1 - 0.0012 18.9 5.4 0.005 16.9 0.3 3.0 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_17 PF13431.6 KND90200.1 - 0.0069 16.7 0.0 9.2 6.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KND90200.1 - 0.66 9.0 8.7 2.2 7.3 0.1 4.0 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KND90200.1 - 0.89 9.5 3.6 67 3.5 0.1 4.6 5 2 0 5 5 5 0 Mad3/BUB1 homology region 1 peroxidase PF00141.23 KND90201.1 - 6e-46 157.0 0.0 9.8e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Oxidored_FMN PF00724.20 KND90202.1 - 1.3e-64 218.6 0.0 1.8e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AIRC PF00731.20 KND90203.1 - 5.4e-60 201.3 2.6 7.7e-60 200.8 1.5 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 KND90203.1 - 1.9e-47 161.0 0.0 9.9e-47 158.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 KND90203.1 - 4.8e-14 51.8 0.0 1.3e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KND90203.1 - 1.6e-05 24.5 0.0 4.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 KND90203.1 - 0.0053 17.3 0.1 4 8.0 0.0 2.7 2 1 0 2 2 2 2 XdhC Rossmann domain CoA_binding_2 PF13380.6 KND90203.1 - 0.011 16.2 4.0 1.6 9.3 0.0 4.2 3 2 1 4 4 4 0 CoA binding domain PrpR_N PF06506.11 KND90203.1 - 0.014 15.0 0.1 0.12 12.0 0.0 2.4 3 0 0 3 3 3 0 Propionate catabolism activator Thioredoxin PF00085.20 KND90204.1 - 3e-64 213.5 8.8 6.9e-32 109.5 0.2 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 KND90204.1 - 2.8e-49 167.5 2.8 1.2e-38 132.8 1.2 3.6 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KND90204.1 - 2.7e-09 37.2 0.3 0.028 14.7 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.6 KND90204.1 - 2.4e-08 34.1 0.0 0.00088 19.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KND90204.1 - 1.4e-07 31.2 6.2 0.0066 15.8 0.0 3.3 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KND90204.1 - 1.5e-07 30.8 0.7 1.5e-07 30.8 0.7 2.3 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 KND90204.1 - 1.7e-07 31.7 0.7 0.0033 17.9 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 KND90204.1 - 1.9e-07 31.0 1.5 0.011 15.6 0.1 3.5 3 1 1 4 4 4 2 AhpC/TSA family ERp29_N PF07912.13 KND90204.1 - 9.5e-07 29.0 1.1 4.3 7.5 0.0 4.4 4 0 0 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 KND90204.1 - 1.8e-05 24.5 1.6 0.032 14.0 0.0 3.3 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 KND90204.1 - 0.019 15.0 0.1 0.099 12.7 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin domain DSBA PF01323.20 KND90204.1 - 0.056 13.2 0.1 13 5.5 0.0 3.1 2 1 0 2 2 2 0 DSBA-like thioredoxin domain DUF4642 PF15484.6 KND90204.1 - 0.084 13.1 6.4 0.14 12.4 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) CPSF100_C PF13299.6 KND90204.1 - 0.086 13.0 3.1 0.15 12.3 3.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 KND90204.1 - 2.3 8.7 7.1 5 7.5 7.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Thioredoxin_4 PF13462.6 KND90204.1 - 2.8 8.1 12.8 7.6 6.7 3.7 3.9 3 2 0 3 3 3 0 Thioredoxin Band_7 PF01145.25 KND90205.1 - 9.2e-23 81.2 4.2 1.7e-22 80.3 4.2 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family RepB-RCR_reg PF10723.9 KND90205.1 - 0.059 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB Elongin_A PF06881.11 KND90206.1 - 4.3e-26 91.5 1.6 8.9e-26 90.5 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNA_pol_Rpb4 PF03874.16 KND90207.1 - 9.7e-27 93.7 5.4 1.2e-26 93.4 5.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Spexin PF15171.6 KND90207.1 - 0.023 14.9 1.1 0.032 14.4 0.2 1.7 2 0 0 2 2 2 0 Neuropeptide secretory protein family, NPQ, spexin Mu-like_Pro PF10123.9 KND90207.1 - 0.14 11.7 2.4 0.16 11.5 2.4 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Com_YlbF PF06133.11 KND90207.1 - 0.43 11.2 4.5 11 6.7 0.3 2.2 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Sybindin PF04099.12 KND90208.1 - 5.1e-50 169.1 0.0 6.2e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KND90208.1 - 2.7e-07 30.8 0.0 3.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region CPL PF08144.11 KND90209.1 - 8e-44 149.5 0.3 9.1e-43 146.0 0.0 2.9 4 0 0 4 4 4 1 CPL (NUC119) domain TraH_2 PF06871.11 KND90209.1 - 5.6 6.6 7.5 0.22 11.2 0.3 2.0 2 0 0 2 2 2 0 TraH_2 SUI1 PF01253.22 KND90211.1 - 2e-21 76.3 0.7 2e-21 76.3 0.7 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 KND90211.1 - 0.0064 16.8 0.4 0.015 15.6 0.1 1.9 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) MscS_TM PF12794.7 KND90211.1 - 0.22 10.4 1.5 0.32 9.8 1.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Methyltransf_11 PF08241.12 KND90212.1 - 2e-13 50.8 0.0 4.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND90212.1 - 1.9e-05 25.3 0.0 4.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90212.1 - 0.0044 17.7 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND90212.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KND90212.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VWA_2 PF13519.6 KND90213.1 - 3e-25 88.9 0.3 8.4e-25 87.5 0.0 1.9 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 KND90213.1 - 8.1e-12 45.7 0.3 1.1e-11 45.4 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KND90213.1 - 3.7e-08 33.4 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KND90213.1 - 0.036 14.0 1.4 0.036 14.0 1.4 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 KND90214.1 - 3.1e-23 81.2 2.6 4.9e-23 80.5 2.6 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal ATP-synt_ab PF00006.25 KND90215.1 - 1.9e-71 240.1 0.0 2.7e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KND90215.1 - 2.2e-47 160.5 0.5 3.6e-47 159.8 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KND90215.1 - 1.1e-14 54.6 2.5 2.5e-14 53.5 2.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SH3_3 PF08239.11 KND90216.1 - 0.078 13.3 0.0 0.9 9.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain NAD_kinase PF01513.21 KND90217.1 - 4.5e-81 272.2 0.0 6.5e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KND90218.1 - 4.8e-11 43.3 0.0 7.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND90218.1 - 0.0039 17.2 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ras PF00071.22 KND90219.1 - 3.5e-49 166.5 0.0 4.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND90219.1 - 1.1e-29 103.1 0.1 2.8e-29 101.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND90219.1 - 1.7e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND90219.1 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KND90219.1 - 0.00056 20.3 0.1 0.0036 17.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 KND90219.1 - 0.0024 17.3 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KND90219.1 - 0.015 14.8 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 KND90219.1 - 0.016 14.4 2.1 0.56 9.3 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 KND90219.1 - 0.023 14.2 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KND90219.1 - 0.023 14.6 0.1 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KND90219.1 - 0.059 13.1 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND90219.1 - 0.087 12.8 0.1 0.2 11.7 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 KND90219.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KND90219.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KND90219.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 KND90219.1 - 0.15 11.3 0.5 0.22 10.8 0.1 1.5 2 0 0 2 2 2 0 Septin ATPase PF06745.13 KND90219.1 - 0.21 10.9 0.2 0.32 10.3 0.2 1.2 1 0 0 1 1 1 0 KaiC Homeodomain PF00046.29 KND90220.1 - 1.2e-13 50.7 2.5 2.9e-13 49.5 2.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KND90220.1 - 0.042 13.8 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain CBM9_2 PF16011.5 KND90221.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 Carb_kinase PF01256.17 KND90222.1 - 2.1e-52 178.0 0.0 2.7e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KND90222.1 - 0.022 14.2 0.0 0.053 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF2623 PF11115.8 KND90224.1 - 0.11 12.6 0.0 19 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) NPL PF17800.1 KND90225.1 - 5.1e-34 117.0 8.9 3.8e-33 114.2 8.9 2.4 1 1 0 1 1 1 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KND90225.1 - 7.8e-31 106.3 0.0 2.1e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase PF00069.25 KND90226.1 - 1.6e-41 142.4 0.0 3.4e-32 111.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND90226.1 - 3.1e-19 69.3 0.0 2e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KND90226.1 - 0.0021 18.0 0.1 0.0065 16.4 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND90226.1 - 0.0064 15.5 0.8 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain SSFA2_C PF14723.6 KND90226.1 - 0.026 14.5 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Pox_ser-thr_kin PF05445.11 KND90226.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RabGAP-TBC PF00566.18 KND90227.1 - 1.9e-32 112.7 0.0 1.2e-31 110.1 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FmiP_Thoc5 PF09766.9 KND90228.1 - 3.2e-29 102.4 13.4 4.8e-29 101.8 13.4 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 KND90228.1 - 0.0073 16.4 3.9 0.0073 16.4 3.9 2.3 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus Casc1_N PF15927.5 KND90228.1 - 0.017 14.8 8.9 0.017 14.8 8.9 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus CENP-F_leu_zip PF10473.9 KND90228.1 - 0.15 12.0 12.2 0.41 10.7 4.6 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KND90228.1 - 0.85 9.7 3.0 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3958 PF13125.6 KND90228.1 - 1.6 9.0 16.1 8.2 6.7 11.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) K-box PF01486.17 KND90228.1 - 2.5 8.3 14.6 0.43 10.8 9.0 2.5 2 1 1 3 3 3 0 K-box region APG6_N PF17675.1 KND90228.1 - 3.6 8.1 19.6 0.85 10.1 7.6 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Flagellin_N PF00669.20 KND90228.1 - 5.6 7.1 9.0 1.9 8.6 1.1 2.2 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Glyco_trans_2_3 PF13632.6 KND90229.1 - 6.1e-20 72.0 0.4 6.1e-20 72.0 0.4 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND90229.1 - 3.6e-05 23.8 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DJ-1_PfpI PF01965.24 KND90230.1 - 3e-08 33.6 0.0 3.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family WLM PF08325.10 KND90232.1 - 1.4e-19 70.9 1.8 1.4e-19 70.9 1.8 2.0 1 1 1 2 2 2 1 WLM domain DUF45 PF01863.17 KND90232.1 - 1.1e-06 28.9 0.9 1.1e-06 28.9 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 Sulfate_transp PF00916.20 KND90233.1 - 1.2e-109 366.5 16.5 1.6e-109 366.2 16.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND90233.1 - 6.1e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KND90233.1 - 9.3e-05 22.8 3.2 9.3e-05 22.8 3.2 3.5 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily HlyIII PF03006.20 KND90234.1 - 7.7e-59 199.1 18.7 9.4e-59 198.8 18.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4220 PF13968.6 KND90234.1 - 3.7 6.9 7.9 11 5.3 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) PNP_UDP_1 PF01048.20 KND90235.1 - 0.0019 17.5 0.4 0.0026 17.0 0.4 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily Pex14_N PF04695.13 KND90236.1 - 0.0041 17.8 2.3 0.0041 17.8 2.3 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1294 PF06961.13 KND90236.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1294) CsbD PF05532.12 KND90238.1 - 3.5e-09 36.4 8.6 9.3e-05 22.3 1.2 2.1 1 1 1 2 2 2 2 CsbD-like Peptidase_S24 PF00717.23 KND90239.1 - 1.3e-06 28.3 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rep_fac_C PF08542.11 KND90240.1 - 7.6e-22 77.5 0.0 1.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KND90240.1 - 9.6e-17 61.6 0.0 3.8e-16 59.7 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KND90240.1 - 2.5e-12 46.9 0.0 5.5e-11 42.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KND90240.1 - 1.6e-09 38.0 0.0 4.3e-09 36.6 0.0 1.8 2 1 0 2 2 1 1 Rad17 P-loop domain AAA_16 PF13191.6 KND90240.1 - 4.4e-05 23.9 0.0 0.0019 18.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 KND90240.1 - 5.7e-05 23.0 0.1 0.00017 21.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KND90240.1 - 6.4e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 KND90240.1 - 8.7e-05 22.8 0.0 0.00023 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 KND90240.1 - 8.7e-05 22.8 0.2 0.0055 17.0 0.0 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KND90240.1 - 0.00013 21.7 0.0 0.00041 20.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KND90240.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KND90240.1 - 0.0017 17.8 0.0 0.063 12.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KND90240.1 - 0.0025 18.1 0.0 0.015 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KND90240.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KND90240.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND90240.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KND90240.1 - 0.016 14.9 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND90240.1 - 0.019 14.9 0.1 0.17 11.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 KND90240.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KND90240.1 - 0.026 14.8 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KND90240.1 - 0.06 13.9 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 KND90240.1 - 0.073 12.8 0.1 0.58 9.9 0.0 2.2 2 1 1 3 3 2 0 DEAD/DEAH box helicase AAA_3 PF07726.11 KND90240.1 - 0.074 12.9 0.0 0.6 10.0 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 KND90240.1 - 0.079 13.0 0.0 0.68 9.9 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KND90240.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KND90240.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FAM184 PF15665.5 KND90241.1 - 0.3 10.8 3.2 18 5.0 3.2 2.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Sec63 PF02889.16 KND90242.1 - 2.9e-163 541.1 0.0 8.7e-93 310.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KND90242.1 - 2.4e-36 125.1 0.3 5.7e-22 78.3 0.2 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KND90242.1 - 1.8e-17 63.9 0.1 6.7e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND90242.1 - 5.1e-10 39.7 0.0 2e-07 31.3 0.0 3.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KND90242.1 - 0.00023 21.4 0.1 0.12 12.7 0.1 3.1 2 1 0 2 2 2 1 AAA domain TFIIE_alpha PF02002.17 KND90242.1 - 0.0024 17.7 0.2 2.3 8.1 0.0 3.1 2 0 0 2 2 2 2 TFIIE alpha subunit PhoH PF02562.16 KND90242.1 - 0.1 12.0 0.0 3.8 6.9 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Helicase_PWI PF18149.1 KND90243.1 - 6e-32 110.1 0.3 6e-32 110.1 0.3 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain NBP1 PF08537.10 KND90243.1 - 0.04 13.3 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF2417 PF10329.9 KND90244.1 - 1.3e-86 289.9 2.6 1.8e-86 289.4 2.6 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 KND90244.1 - 0.33 9.2 13.6 0.45 8.8 13.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3357 PF11837.8 KND90244.1 - 8.7 6.9 6.0 6.1 7.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) RhoGAP PF00620.27 KND90245.1 - 2.7e-35 121.4 0.0 5.6e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KND90245.1 - 4.5e-28 97.3 42.1 2.2e-11 43.8 5.9 5.0 5 0 0 5 5 5 4 LIM domain zf_C2H2_13 PF18508.1 KND90245.1 - 0.056 13.0 1.2 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-ACC PF17848.1 KND90245.1 - 1.3 9.2 8.4 37 4.5 0.1 4.6 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zf_PR_Knuckle PF18445.1 KND90245.1 - 2.2 8.1 4.7 0.48 10.3 0.2 2.2 2 0 0 2 2 2 0 PR zinc knuckle motif UQ_con PF00179.26 KND90246.1 - 4.2e-44 149.6 0.0 8.5e-30 103.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 KND90246.1 - 0.04 14.2 0.0 5.3 7.4 0.0 2.6 2 1 0 2 2 2 0 RWD domain UEV PF05743.13 KND90246.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 KND90246.1 - 0.072 12.8 0.0 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family B DUF695 PF05117.12 KND90246.1 - 0.15 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF695) 3Beta_HSD PF01073.19 KND90248.1 - 7.2e-66 222.0 0.0 9.4e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KND90248.1 - 3.4e-32 111.8 0.3 4.6e-32 111.4 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND90248.1 - 1.7e-17 63.5 0.6 2.4e-17 63.0 0.6 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KND90248.1 - 7.7e-14 51.8 0.0 4e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KND90248.1 - 2e-13 50.6 1.0 3e-13 50.1 1.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KND90248.1 - 3.8e-11 42.6 0.0 3.4e-09 36.2 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KND90248.1 - 5.4e-07 29.0 0.6 2.1e-06 27.1 0.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 KND90248.1 - 0.0073 16.2 2.0 0.044 13.7 2.0 2.1 1 1 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 KND90248.1 - 0.06 13.3 0.0 0.21 11.6 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase Family 4 FtsJ PF01728.19 KND90248.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glyco_trans_4_2 PF13477.6 KND90248.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like GN3L_Grn1 PF08701.11 KND90250.1 - 3.6e-24 84.6 14.7 6.5e-24 83.8 14.7 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KND90250.1 - 3e-17 62.8 0.2 9.4e-13 48.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND90250.1 - 8.2e-10 38.8 0.0 3.1e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KND90250.1 - 1.4e-06 28.0 0.0 0.031 13.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KND90250.1 - 2.3e-06 27.8 4.4 0.023 14.7 0.1 3.7 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 KND90250.1 - 0.00049 19.7 0.3 0.019 14.5 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Nuc_deoxyri_tr2 PF15891.5 KND90250.1 - 0.036 14.4 0.5 0.68 10.3 0.0 2.5 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like MeaB PF03308.16 KND90250.1 - 0.038 13.0 0.1 0.038 13.0 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KND90250.1 - 0.057 12.7 0.2 0.31 10.4 0.1 2.1 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 KND90250.1 - 0.71 10.2 8.3 0.44 10.9 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain UPF0767 PF15990.5 KND90250.1 - 1.8 8.8 3.9 85 3.4 0.0 3.3 3 0 0 3 3 3 0 UPF0767 family CRT10 PF08728.10 KND90250.1 - 4.3 5.4 4.3 5.7 5.0 4.3 1.1 1 0 0 1 1 1 0 CRT10 RNB PF00773.19 KND90251.1 - 8.9e-101 337.5 0.1 1.6e-100 336.6 0.1 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KND90251.1 - 5.6e-32 109.6 0.6 1.5e-31 108.2 0.1 2.0 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KND90251.1 - 1.5e-29 102.6 0.2 5.1e-29 100.9 0.2 1.9 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KND90251.1 - 3.8e-19 68.5 0.0 1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KND90251.1 - 1.3e-07 31.9 0.1 6.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 KND90251.1 - 2.2e-07 30.9 0.4 0.0078 16.4 0.0 3.3 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 KND90251.1 - 0.013 15.8 0.0 0.048 14.0 0.0 2.0 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal DUF3915 PF13054.6 KND90252.1 - 0.057 13.4 7.7 0.14 12.2 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Tim54 PF11711.8 KND90253.1 - 1.5e-142 474.8 1.1 1.8e-142 474.6 1.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 SF3A2 PF16835.5 KND90255.1 - 5.3e-33 113.3 0.0 8.2e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KND90255.1 - 3.8e-06 27.1 0.9 6.8e-06 26.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 KND90255.1 - 3.2e-05 23.9 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 KND90255.1 - 0.066 12.8 1.5 0.11 12.1 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Aminotran_3 PF00202.21 KND90256.1 - 3.6e-46 157.6 1.0 5e-45 153.9 1.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KND90256.1 - 0.044 13.1 0.1 0.094 12.0 0.1 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KND90256.1 - 0.059 12.7 0.2 0.1 11.8 0.2 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-met PF12874.7 KND90257.1 - 2.3e-07 31.0 6.8 2.3e-05 24.6 2.7 3.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 KND90257.1 - 6.7e-07 29.4 12.8 0.00092 19.5 1.7 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KND90257.1 - 1.7e-06 28.1 9.5 0.00072 19.8 0.2 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KND90257.1 - 2.3e-06 27.9 23.9 0.00084 20.0 0.1 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND90257.1 - 0.0048 16.9 0.1 0.0048 16.9 0.1 3.1 2 1 1 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 KND90257.1 - 0.08 13.3 22.2 0.092 13.1 0.4 3.9 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KND90257.1 - 2 9.0 15.3 2.8 8.5 0.6 4.2 5 0 0 5 5 5 0 Zinc-finger double domain CBFD_NFYB_HMF PF00808.23 KND90258.1 - 3.7e-10 40.0 0.0 6.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND90258.1 - 6.9e-06 26.4 0.5 6.9e-06 26.4 0.5 2.2 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KND90258.1 - 0.0027 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAFII28 PF04719.14 KND90258.1 - 0.11 12.6 0.1 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 hTAFII28-like protein conserved region DNA_mis_repair PF01119.19 KND90259.1 - 1.5e-11 44.0 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KND90260.1 - 1.5e-16 60.5 0.1 1.8e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KND90260.1 - 2.9e-10 40.6 0.1 3.8e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_RNA_Pol_19 PF05320.12 KND90260.1 - 0.032 14.2 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TRP PF06011.12 KND90261.1 - 3.2e-39 134.9 19.6 3.4e-38 131.5 19.6 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND90261.1 - 1.7e-25 90.0 0.1 2.6e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 ML-like domain HAP1_N PF04849.13 KND90263.1 - 1.3e-05 24.5 1.0 1.3e-05 24.5 1.0 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Yippee-Mis18 PF03226.14 KND90263.1 - 5.6e-05 23.3 5.7 0.00011 22.4 3.4 2.2 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MscS_porin PF12795.7 KND90263.1 - 0.00017 21.2 13.0 0.00018 21.1 9.6 2.2 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain TMF_TATA_bd PF12325.8 KND90263.1 - 0.00028 21.1 13.2 0.024 14.8 1.0 3.5 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 KND90263.1 - 0.00036 20.5 4.0 0.00036 20.5 4.0 4.4 5 0 0 5 5 4 1 TolA binding protein trimerisation Fez1 PF06818.15 KND90263.1 - 0.00041 20.9 12.2 0.00066 20.2 9.8 2.3 2 1 0 2 2 2 1 Fez1 Filament PF00038.21 KND90263.1 - 0.00043 20.0 11.5 0.00049 19.8 2.6 2.5 1 1 1 2 2 2 1 Intermediate filament protein FlaC_arch PF05377.11 KND90263.1 - 0.00085 19.7 3.2 0.99 9.9 0.1 4.6 4 1 1 5 5 5 1 Flagella accessory protein C (FlaC) PV-1 PF06637.11 KND90263.1 - 0.0013 17.6 4.8 0.002 17.0 4.8 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) EzrA PF06160.12 KND90263.1 - 0.0018 16.5 3.4 0.006 14.8 2.7 1.9 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 KND90263.1 - 0.0021 18.2 5.0 1.9 8.6 0.3 3.4 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family Myosin_tail_1 PF01576.19 KND90263.1 - 0.0025 15.7 8.4 0.0025 15.7 8.4 1.5 1 1 0 1 1 1 1 Myosin tail FliJ PF02050.16 KND90263.1 - 0.0042 17.3 14.1 0.013 15.8 6.0 3.6 1 1 4 5 5 5 2 Flagellar FliJ protein Spc7 PF08317.11 KND90263.1 - 0.0044 15.9 12.1 0.015 14.2 5.9 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein Leu_zip PF15294.6 KND90263.1 - 0.0046 16.5 6.9 0.01 15.4 1.0 2.2 1 1 1 2 2 2 1 Leucine zipper MAD PF05557.13 KND90263.1 - 0.0061 15.0 12.0 0.061 11.7 12.4 1.9 1 1 1 2 2 2 1 Mitotic checkpoint protein SlyX PF04102.12 KND90263.1 - 0.0082 16.7 15.9 0.36 11.5 3.2 4.4 4 0 0 4 4 4 1 SlyX DUF4407 PF14362.6 KND90263.1 - 0.0095 15.3 10.8 0.076 12.4 10.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) WEMBL PF05701.11 KND90263.1 - 0.011 14.5 8.0 0.1 11.3 8.1 2.2 1 1 0 1 1 1 0 Weak chloroplast movement under blue light ADIP PF11559.8 KND90263.1 - 0.019 15.1 11.2 0.25 11.4 5.4 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 KND90263.1 - 0.023 14.4 6.2 0.06 13.1 6.2 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 KND90263.1 - 0.028 14.4 7.6 0.95 9.5 0.6 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) CortBP2 PF09727.9 KND90263.1 - 0.031 14.2 4.9 0.061 13.2 4.9 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 HMMR_C PF15908.5 KND90263.1 - 0.038 14.2 3.5 0.044 14.0 1.0 2.4 3 0 0 3 3 1 0 Hyaluronan mediated motility receptor C-terminal Baculo_PEP_C PF04513.12 KND90263.1 - 0.043 13.8 2.0 4.5 7.3 0.0 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 KND90263.1 - 0.061 13.9 17.4 3.8 8.2 5.5 4.3 1 1 4 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4201 PF13870.6 KND90263.1 - 0.061 13.0 6.1 0.13 12.0 3.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Golgin_A5 PF09787.9 KND90263.1 - 0.071 12.6 14.6 0.097 12.1 11.5 2.5 2 1 1 3 3 2 0 Golgin subfamily A member 5 Lebercilin PF15619.6 KND90263.1 - 0.078 12.6 11.3 0.034 13.8 8.3 1.9 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 KND90263.1 - 0.091 10.3 13.7 0.08 10.5 12.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2730 PF10805.8 KND90263.1 - 0.091 12.9 5.5 0.7 10.0 0.4 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.20 KND90263.1 - 0.098 12.6 4.7 7 6.7 0.2 3.7 3 1 0 4 4 3 0 Prefoldin subunit SASP PF00269.20 KND90263.1 - 0.1 12.6 0.3 0.95 9.5 0.1 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type FAM76 PF16046.5 KND90263.1 - 0.13 11.6 7.4 0.058 12.7 4.6 1.8 1 1 1 2 2 2 0 FAM76 protein CLZ PF16526.5 KND90263.1 - 0.15 12.4 4.4 13 6.3 0.8 3.2 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spectrin PF00435.21 KND90263.1 - 0.17 12.4 6.5 1.2 9.6 0.0 3.5 2 1 0 3 3 3 0 Spectrin repeat FH2 PF02181.23 KND90263.1 - 0.22 10.6 6.1 2.6 7.1 0.2 2.9 1 1 2 3 3 3 0 Formin Homology 2 Domain THOC7 PF05615.13 KND90263.1 - 0.26 11.6 16.8 2.2 8.6 3.7 4.1 1 1 2 3 3 3 0 Tho complex subunit 7 YabA PF06156.13 KND90263.1 - 0.26 11.9 7.4 34 5.1 4.5 4.0 1 1 2 3 3 3 0 Initiation control protein YabA Rab5-bind PF09311.11 KND90263.1 - 0.31 10.4 12.1 1.6 8.1 12.1 1.8 1 1 0 1 1 1 0 Rabaptin-like protein Laminin_II PF06009.12 KND90263.1 - 0.35 10.9 10.4 7.6 6.6 4.1 3.2 2 1 1 3 3 3 0 Laminin Domain II DUF2353 PF09789.9 KND90263.1 - 0.35 10.2 11.3 0.61 9.4 4.6 2.4 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) PRKG1_interact PF15898.5 KND90263.1 - 0.35 11.8 14.2 1.3 10.0 5.1 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 KND90263.1 - 0.36 10.0 6.5 0.58 9.3 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1090 PF06476.12 KND90263.1 - 0.38 10.9 5.8 0.27 11.4 0.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1090) Atg14 PF10186.9 KND90263.1 - 0.39 9.8 12.9 14 4.6 12.9 2.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lzipper-MIP1 PF14389.6 KND90263.1 - 0.41 11.0 6.5 1.7 9.0 0.9 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 KASH_CCD PF14662.6 KND90263.1 - 0.42 10.4 11.3 1.2 9.0 10.2 2.2 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 KND90263.1 - 0.5 10.4 12.3 0.78 9.8 2.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Csm1_N PF18504.1 KND90263.1 - 0.61 10.5 11.5 7.9 6.9 1.8 4.3 4 1 0 4 4 4 0 Csm1 N-terminal domain LPP PF04728.13 KND90263.1 - 0.62 10.5 10.4 19 5.7 1.4 4.6 4 1 0 4 4 4 0 Lipoprotein leucine-zipper YlqD PF11068.8 KND90263.1 - 0.62 10.4 14.1 1 9.7 1.6 3.3 1 1 2 3 3 3 0 YlqD protein BST2 PF16716.5 KND90263.1 - 0.62 10.7 10.6 1.7 9.2 4.1 3.7 2 1 2 4 4 3 0 Bone marrow stromal antigen 2 PKcGMP_CC PF16808.5 KND90263.1 - 0.64 9.9 2.2 0.68 9.8 0.1 2.1 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5082 PF16888.5 KND90263.1 - 0.67 10.2 5.6 5.7 7.2 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 KND90263.1 - 0.68 10.5 11.2 3.3 8.3 9.4 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Wtap PF17098.5 KND90263.1 - 0.7 9.8 12.0 22 5.0 0.2 2.6 1 1 1 2 2 2 0 WTAP/Mum2p family DHR10 PF18595.1 KND90263.1 - 0.81 9.8 15.0 0.096 12.7 4.8 3.2 3 1 0 3 3 2 0 Designed helical repeat protein 10 domain Syntaxin_2 PF14523.6 KND90263.1 - 0.85 10.0 8.3 0.32 11.4 0.8 3.2 1 1 2 3 3 3 0 Syntaxin-like protein DUF948 PF06103.11 KND90263.1 - 0.9 9.8 2.8 12 6.2 0.4 2.9 1 1 3 4 4 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_L29 PF00831.23 KND90263.1 - 1.2 9.2 10.3 3.1 7.8 0.3 3.0 3 0 0 3 3 2 0 Ribosomal L29 protein GAS PF13851.6 KND90263.1 - 1.2 8.4 10.8 2 7.7 7.4 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FlxA PF14282.6 KND90263.1 - 1.2 9.2 13.5 12 6.0 5.3 4.1 1 1 3 4 4 4 0 FlxA-like protein DUF724 PF05266.14 KND90263.1 - 1.4 8.7 9.5 3.7 7.3 0.9 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 KND90263.1 - 1.5 9.3 17.3 4.1 7.9 2.6 4.0 2 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 KND90263.1 - 1.6 9.3 4.9 9.2 6.8 0.2 3.4 3 1 1 4 4 2 0 Nucleopolyhedrovirus P10 protein DUF4472 PF14739.6 KND90263.1 - 1.6 9.5 9.1 0.34 11.6 2.2 3.0 2 1 2 4 4 3 0 Domain of unknown function (DUF4472) Uso1_p115_C PF04871.13 KND90263.1 - 2.1 8.7 14.5 2.5 8.5 3.5 3.2 2 1 2 4 4 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region PspA_IM30 PF04012.12 KND90263.1 - 2.3 7.7 18.4 2.2 7.8 5.5 3.2 1 1 1 2 2 2 0 PspA/IM30 family TRAF_BIRC3_bd PF16673.5 KND90263.1 - 2.7 7.9 6.5 17 5.3 0.1 3.4 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Prefoldin PF02996.17 KND90263.1 - 3.2 7.7 7.5 28 4.7 0.0 3.7 4 0 0 4 4 3 0 Prefoldin subunit zf-C4H2 PF10146.9 KND90263.1 - 4 7.7 8.6 4.4 7.6 6.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Jnk-SapK_ap_N PF09744.9 KND90263.1 - 4.1 7.6 14.4 0.24 11.6 2.4 2.8 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 KND90263.1 - 4.2 7.5 14.3 1.7 8.7 4.3 3.5 1 1 1 2 2 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 KND90263.1 - 4.2 7.5 8.9 3.8 7.6 0.7 3.2 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.12 KND90263.1 - 4.3 7.7 11.8 7.4 6.9 5.7 3.3 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) USP8_interact PF08941.10 KND90263.1 - 4.3 7.1 6.1 17 5.2 0.2 2.9 1 1 2 3 3 3 0 USP8 interacting CorA PF01544.18 KND90263.1 - 4.6 6.5 7.1 0.68 9.2 2.3 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CC2-LZ PF16516.5 KND90263.1 - 8.2 6.9 9.0 5.8 7.3 1.0 3.7 1 1 2 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator RNase_T PF00929.24 KND90264.1 - 9.5e-10 39.3 0.0 2.1e-09 38.1 0.0 1.6 1 1 0 1 1 1 1 Exonuclease SIL1 PF16782.5 KND90265.1 - 3.8e-13 49.3 0.0 4.8e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 SET PF00856.28 KND90266.1 - 9e-10 39.2 0.0 6.7e-09 36.3 0.0 2.4 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 KND90266.1 - 3.4e-07 30.2 13.2 3.4e-07 30.2 13.2 2.4 3 0 0 3 3 3 1 MYND finger zinc-ribbons_6 PF07191.12 KND90266.1 - 5.4 7.1 10.4 0.37 10.8 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbons Glutaredoxin PF00462.24 KND90268.1 - 4.4e-13 49.2 0.0 1.3e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 KND90268.1 - 2.7e-05 24.5 0.0 0.00016 22.0 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain Epimerase PF01370.21 KND90269.1 - 3.1e-16 59.6 0.0 4.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND90269.1 - 7.3e-09 35.1 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KND90269.1 - 2.1e-05 24.1 0.0 3.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND90269.1 - 0.0036 16.4 0.0 0.013 14.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KND90269.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 KND90269.1 - 0.039 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Prok-E2_D PF14460.6 KND90269.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family D KR PF08659.10 KND90269.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 KR domain AphA_like PF14557.6 KND90270.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Mito_carr PF00153.27 KND90271.1 - 2.7e-48 161.8 7.0 4.1e-19 68.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Yos1 PF08571.10 KND90272.1 - 2e-33 114.5 0.4 2.5e-33 114.2 0.4 1.1 1 0 0 1 1 1 1 Yos1-like DUF3602 PF12223.8 KND90273.1 - 1.1e-22 80.4 7.4 1.1e-22 80.4 7.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) ATG22 PF11700.8 KND90274.1 - 6.2e-192 638.5 7.3 1.8e-191 637.0 7.3 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like PHD PF00628.29 KND90275.1 - 0.0098 15.8 2.3 0.022 14.7 2.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KND90275.1 - 0.055 13.7 0.4 0.055 13.7 0.4 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 KND90275.1 - 0.087 13.1 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 RING-like domain F_actin_cap_B PF01115.17 KND90276.1 - 9.4e-105 349.5 0.0 1.1e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF836 PF05768.14 KND90277.1 - 1.6e-11 44.5 0.0 1.9e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 KND90277.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin CHORD PF04968.12 KND90278.1 - 4.3e-49 165.1 20.6 2.9e-25 88.7 6.6 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KND90278.1 - 3e-14 53.8 0.0 4.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 CS domain V-ATPase_H_N PF03224.14 KND90279.1 - 4.7e-70 236.4 0.0 6.5e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KND90279.1 - 7.1e-36 122.9 0.1 2.5e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 KND90279.1 - 0.016 15.5 0.1 0.15 12.4 0.0 2.5 2 1 0 2 2 2 0 HEAT repeats OmdA PF13376.6 KND90279.1 - 1 9.4 2.8 13 5.9 0.8 2.8 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated RIX1 PF08167.12 KND90279.1 - 8.8 6.0 6.6 10 5.8 0.0 3.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis GCV_T PF01571.21 KND90280.1 - 8.9e-80 267.8 0.0 1.1e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KND90280.1 - 6.4e-23 80.5 0.8 3.2e-22 78.2 0.7 2.3 3 0 0 3 3 3 1 Glycine cleavage T-protein C-terminal barrel domain TAP42 PF04177.12 KND90282.1 - 0.014 14.6 0.2 0.014 14.6 0.2 2.3 3 0 0 3 3 3 0 TAP42-like family PBP1_TM PF14812.6 KND90282.1 - 0.11 12.9 24.0 0.35 11.3 1.7 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPT6_acidic PF14632.6 KND90282.1 - 1.4 9.5 22.9 4.3 8.0 2.5 3.6 3 0 0 3 3 3 0 Acidic N-terminal SPT6 Zn_clus PF00172.18 KND90283.1 - 4.6e-10 39.4 6.5 8.6e-10 38.6 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.14 KND90284.1 - 7.9e-13 48.6 0.3 3.9e-05 23.9 0.3 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF1765 PF08578.10 KND90285.1 - 7.3e-41 139.5 6.8 1.3e-40 138.7 6.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) HARP PF07443.13 KND90285.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 HepA-related protein (HARP) PhoD PF09423.10 KND90286.1 - 1.3e-06 27.7 0.1 9.7e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Aldedh PF00171.22 KND90287.1 - 3.6e-105 352.2 0.1 5.2e-105 351.6 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Per1 PF04080.13 KND90288.1 - 5.2e-105 350.8 14.3 7.2e-105 350.3 14.3 1.2 1 0 0 1 1 1 1 Per1-like family Sec10 PF07393.11 KND90289.1 - 2.1e-219 730.6 4.5 2.5e-219 730.4 4.5 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Methyltransf_23 PF13489.6 KND90289.1 - 0.043 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Prenyltransf PF01255.19 KND90290.1 - 1.3e-06 28.1 0.0 4.8e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase NACHT_N PF17100.5 KND90290.1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase RNB PF00773.19 KND90291.1 - 3.9e-47 161.2 0.0 5.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 RNB domain PHP_C PF13263.6 KND90292.1 - 0.081 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 PHP-associated Met_10 PF02475.16 KND90293.1 - 9.4e-70 234.4 0.0 1.2e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.10 KND90294.1 - 5.9e-13 48.4 4.8 1.2e-12 47.4 4.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) zf-HIT PF04438.16 KND90295.1 - 7.9e-10 38.4 5.2 1.3e-09 37.7 5.2 1.4 1 0 0 1 1 1 1 HIT zinc finger zinc_ribbon_2 PF13240.6 KND90295.1 - 1 9.2 3.3 22 4.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain BLOC1_2 PF10046.9 KND90296.1 - 0.1 12.9 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2415 PF10313.9 KND90297.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 KND90297.1 - 0.026 15.4 1.0 0.15 13.0 0.4 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4934 PF16288.5 KND90297.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) tRNA-synt_2b PF00587.25 KND90298.1 - 4.1e-31 108.3 0.0 5.4e-30 104.7 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KND90298.1 - 1.4e-17 63.6 0.0 2.9e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 KND90298.1 - 2.7e-11 43.4 0.0 5.3e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 KND90298.1 - 6e-10 39.0 0.0 1.6e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 TGS domain HSP70 PF00012.20 KND90299.1 - 0.0054 15.0 0.1 0.0059 14.8 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KND90300.1 - 4e-149 497.6 2.1 4e-149 497.6 2.1 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KND90300.1 - 5.5e-11 41.9 1.5 6.2e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein Trans_reg_C PF00486.28 KND90300.1 - 0.11 12.5 0.0 0.87 9.7 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal BLACT_WH PF17778.1 KND90300.1 - 0.14 12.1 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain GTP_EFTU PF00009.27 KND90301.1 - 1.2e-33 116.2 0.0 1.2e-33 116.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KND90301.1 - 1.4e-18 66.9 0.0 3.5e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KND90301.1 - 1.7e-09 38.0 7.2 3.5e-08 33.7 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KND90301.1 - 1.3e-07 31.4 0.9 1.3e-07 31.4 0.9 2.6 2 1 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KND90301.1 - 7e-07 29.3 0.2 2.6e-05 24.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KND90301.1 - 0.00019 21.6 0.0 0.00053 20.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KND90301.1 - 0.00077 19.3 0.2 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.22 KND90301.1 - 0.079 12.6 0.0 0.35 10.5 0.0 2.3 1 1 0 1 1 1 0 Ras family RabGAP-TBC PF00566.18 KND90302.1 - 4.5e-21 75.5 0.0 5.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Vps52 PF04129.12 KND90303.1 - 1.2e-116 390.5 0.1 1.5e-116 390.2 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 KND90303.1 - 8.1e-05 21.2 1.6 0.00012 20.6 1.6 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 eIF-5a PF01287.20 KND90304.1 - 3.2e-28 97.6 1.4 4.7e-28 97.1 1.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KND90304.1 - 0.01 15.9 0.3 0.028 14.4 0.1 1.8 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain NTR2 PF15458.6 KND90304.1 - 0.043 13.4 0.4 0.056 13.0 0.4 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 zf-RRN7 PF11781.8 KND90305.1 - 7.1e-12 44.8 1.0 1.1e-11 44.2 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF35_N PF12172.8 KND90305.1 - 0.016 15.1 0.9 0.037 13.9 0.9 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MIF4G PF02854.19 KND90306.1 - 1.7e-57 194.5 0.0 6.8e-30 104.3 0.0 3.5 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KND90306.1 - 1.5e-39 135.9 8.4 1.5e-39 135.9 8.4 2.7 2 0 0 2 2 2 1 Up-frameshift suppressor 2 RseA_C PF03873.13 KND90306.1 - 0.063 13.5 1.0 0.18 12.1 1.0 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Fib_alpha PF08702.10 KND90306.1 - 0.36 11.0 2.4 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HA2 PF04408.23 KND90308.1 - 6.1e-18 65.1 0.1 3.2e-17 62.8 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KND90308.1 - 6.3e-13 49.0 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KND90308.1 - 9.9e-12 45.1 0.0 2.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KND90308.1 - 1.5e-05 25.3 0.0 3.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KND90308.1 - 0.00012 21.9 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KND90308.1 - 0.00062 20.2 0.4 0.041 14.3 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 KND90308.1 - 0.032 14.7 0.1 0.15 12.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 KND90308.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KND90308.1 - 0.2 12.2 0.1 0.69 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain ING PF12998.7 KND90310.1 - 5.1e-22 78.4 3.1 7.9e-22 77.8 3.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KND90310.1 - 6.5e-05 22.7 9.5 0.00012 21.9 9.5 1.5 1 0 0 1 1 1 1 PHD-finger DUF2552 PF10827.8 KND90310.1 - 0.041 14.1 0.3 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) DUF1704 PF08014.11 KND90310.1 - 0.18 10.8 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) zf-RING_2 PF13639.6 KND90310.1 - 1.3 9.4 6.7 2.5 8.5 6.7 1.5 1 0 0 1 1 1 0 Ring finger domain GTP_EFTU PF00009.27 KND90311.1 - 1.1e-07 31.5 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain URO-D PF01208.17 KND90312.1 - 2.4e-125 418.3 0.0 2.7e-125 418.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) V-SNARE_C PF12352.8 KND90313.1 - 0.71 10.2 6.7 0.25 11.7 3.0 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Velvet PF11754.8 KND90315.1 - 7.3e-91 304.6 0.0 7.3e-91 304.6 0.0 2.6 2 1 0 2 2 2 1 Velvet factor HisG PF01634.18 KND90316.1 - 1.1e-54 184.7 0.0 1.8e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KND90316.1 - 9.6e-28 96.2 0.1 1.9e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain HisG PF01634.18 KND90317.1 - 1.1e-54 184.8 0.0 1.8e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KND90317.1 - 9.5e-28 96.2 0.1 1.8e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain Ceramidase PF05875.12 KND90318.1 - 3.3e-96 321.8 12.8 3.9e-96 321.5 12.8 1.1 1 0 0 1 1 1 1 Ceramidase DUF3479 PF11965.8 KND90318.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) F-box-like PF12937.7 KND90319.1 - 0.00011 22.0 0.1 0.00023 21.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND90319.1 - 0.018 14.9 0.2 0.052 13.5 0.2 1.8 1 1 0 1 1 1 0 F-box domain DNA_pol_B PF00136.21 KND90320.1 - 4.2e-101 338.9 0.0 6.5e-101 338.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KND90320.1 - 2.9e-24 85.8 0.0 2.1e-15 56.7 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KND90320.1 - 2e-17 63.4 3.5 2e-17 63.4 3.5 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slx4 PF09494.10 KND90320.1 - 0.08 12.9 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 Slx4 endonuclease Slu7 PF11708.8 KND90321.1 - 2.5e-74 250.4 16.5 2.5e-74 250.4 16.5 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KND90321.1 - 0.042 13.6 0.6 0.079 12.7 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 KND90321.1 - 0.047 13.8 2.7 0.094 12.8 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Dor1 PF04124.12 KND90322.1 - 1.4e-47 162.1 0.1 1.8e-39 135.4 0.1 2.5 1 1 2 3 3 3 3 Dor1-like family WVELL PF14043.6 KND90322.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 WVELL protein Mito_carr PF00153.27 KND90323.1 - 6.4e-50 167.0 0.8 1.4e-16 60.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KND90323.1 - 0.0038 16.4 0.6 0.33 10.1 0.0 3.1 2 1 0 3 3 3 2 Gammaproteobacterial serine protease TM1586_NiRdase PF14512.6 KND90325.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative TM nitroreductase S4 PF01479.25 KND90326.1 - 2.4e-12 46.4 0.9 2.4e-12 46.4 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KND90326.1 - 4.1e-05 24.4 0.2 7.7e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KND90327.1 - 9.1e-44 147.4 7.6 9.2e-44 147.4 5.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e NaeI PF09126.10 KND90327.1 - 0.0025 17.1 1.7 0.0038 16.5 1.0 1.6 1 1 1 2 2 2 1 Restriction endonuclease NaeI DUF5486 PF17588.2 KND90327.1 - 0.014 15.2 0.6 0.059 13.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) PyocinActivator PF11112.8 KND90327.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Pyocin activator protein PrtN Fungal_trans PF04082.18 KND90328.1 - 1.2e-13 50.8 3.7 1.2e-13 50.7 0.4 2.1 1 1 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.7 KND90328.1 - 0.024 14.5 0.0 0.062 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 KND90328.1 - 0.049 13.5 0.0 0.049 13.5 0.0 2.4 3 0 0 3 3 3 0 F-box domain HSBP1 PF06825.12 KND90328.1 - 0.068 13.0 0.1 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF4350 PF14258.6 KND90329.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) MULE PF10551.9 KND90330.1 - 3.7e-11 43.3 0.0 1.6e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 KND90330.1 - 0.00012 21.0 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Herpes_gE PF02480.16 KND90330.1 - 0.031 13.0 0.2 0.047 12.4 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box PF00646.33 KND90332.1 - 3.8e-08 33.0 0.3 9.3e-08 31.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KND90332.1 - 9.6e-07 28.6 2.4 1.7e-06 27.8 0.2 2.4 2 0 0 2 2 2 1 F-box-like SUIM_assoc PF16619.5 KND90332.1 - 0.068 13.3 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mod_r PF07200.13 KND90334.1 - 1.1e-30 106.7 0.0 1.2e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PSK_trans_fac PF07704.11 KND90334.1 - 1.6 9.5 10.1 1.2 10.0 0.1 2.8 1 1 1 2 2 2 0 Rv0623-like transcription factor Rad60-SLD PF11976.8 KND90335.1 - 4.5e-20 71.3 0.1 5.5e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KND90335.1 - 3.2e-09 36.4 0.0 3.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.12 KND90335.1 - 0.093 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.13 KND90336.1 - 3.7e-185 617.1 0.0 4.4e-185 616.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Ric8 PF10165.9 KND90337.1 - 1.9e-24 86.6 0.1 1.5e-15 57.2 0.1 2.0 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn DUF3704 PF12488.8 KND90337.1 - 0.033 13.9 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) LIM PF00412.22 KND90338.1 - 6.1e-25 87.2 23.9 1.9e-08 34.4 6.8 3.7 3 0 0 3 3 3 3 LIM domain CHCH PF06747.13 KND90338.1 - 0.00083 19.4 1.0 0.0018 18.3 1.0 1.6 1 0 0 1 1 1 1 CHCH domain DUF2321 PF10083.9 KND90338.1 - 0.016 14.8 0.5 0.016 14.8 0.5 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) DZR PF12773.7 KND90338.1 - 2 8.5 26.1 0.5 10.4 9.6 4.2 1 1 2 3 3 3 0 Double zinc ribbon MTCP1 PF08991.10 KND90340.1 - 2.5e-25 88.5 2.0 3.3e-25 88.1 2.0 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COX17 PF05051.13 KND90340.1 - 0.017 15.5 1.8 0.031 14.6 1.8 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KND90340.1 - 0.031 14.3 2.4 0.051 13.6 2.4 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 KND90340.1 - 0.044 13.9 3.7 0.047 13.8 2.6 1.6 2 0 0 2 2 2 0 CHCH domain bZIP_1 PF00170.21 KND90341.1 - 5e-06 26.5 7.0 8.5e-06 25.8 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF5082 PF16888.5 KND90341.1 - 0.033 14.5 2.3 0.051 13.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 KND90341.1 - 1.8 8.7 9.5 0.45 10.6 3.9 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Siva PF05458.12 KND90342.1 - 0.32 10.7 6.3 0.79 9.4 6.3 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) C1_2 PF03107.16 KND90342.1 - 0.44 10.9 9.5 0.9 9.9 9.5 1.5 1 0 0 1 1 1 0 C1 domain Prefoldin PF02996.17 KND90343.1 - 2e-23 82.6 0.3 2.7e-23 82.1 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KND90343.1 - 0.0035 17.3 4.4 0.07 13.1 0.8 2.1 2 0 0 2 2 2 2 Prefoldin subunit Prot_ATP_ID_OB PF16450.5 KND90343.1 - 0.031 14.2 0.2 0.067 13.2 0.2 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain CLZ PF16526.5 KND90343.1 - 0.065 13.6 4.2 3.9 7.9 0.2 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GIT_CC PF16559.5 KND90343.1 - 0.15 11.9 0.5 0.15 11.9 0.5 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 KND90343.1 - 0.31 11.1 1.9 3.9 7.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 KND90343.1 - 0.39 11.0 4.6 6.4 7.1 1.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FadA PF09403.10 KND90343.1 - 1 9.9 6.6 9.2 6.8 1.4 2.2 2 0 0 2 2 2 0 Adhesion protein FadA AAA PF00004.29 KND90345.1 - 3.2e-17 63.2 0.0 9.3e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KND90345.1 - 1.1e-11 44.8 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 KND90345.1 - 3e-11 44.0 0.1 4.1e-10 40.3 0.0 2.7 3 1 0 3 3 2 1 AAA ATPase domain BAH PF01426.18 KND90345.1 - 1.4e-09 37.8 0.0 4.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.6 KND90345.1 - 2.6e-08 34.2 0.0 6.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND90345.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KND90345.1 - 0.0013 18.7 0.0 0.028 14.3 0.0 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KND90345.1 - 0.0089 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.6 KND90345.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KND90345.1 - 0.029 14.9 0.0 0.063 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND90345.1 - 0.042 13.1 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KND90345.1 - 0.046 14.1 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 KND90345.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KND90345.1 - 0.1 11.8 0.0 0.44 9.7 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain AAA_32 PF13654.6 KND90345.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 KND90346.1 - 5.8e-37 125.1 16.7 2.6e-08 34.4 0.3 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90346.1 - 0.00034 20.8 0.1 6.2 7.2 0.1 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND90346.1 - 0.0045 15.7 1.9 6.3 5.3 0.1 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KND90346.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Ank_5 PF13857.6 KND90347.1 - 6.7e-26 90.0 0.6 3.3e-09 36.8 0.2 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND90347.1 - 1.6e-24 86.3 0.0 1.2e-11 45.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND90347.1 - 1.5e-21 74.1 0.1 0.0015 18.8 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KND90347.1 - 1.9e-19 69.2 0.1 0.00096 19.5 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KND90347.1 - 2.4e-17 63.0 0.3 1.6e-06 28.6 0.0 5.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Sharpin_PH PF16764.5 KND90347.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Sharpin PH domain TMF_TATA_bd PF12325.8 KND90348.1 - 1.5e-38 131.6 8.5 1.5e-38 131.6 8.5 6.4 2 1 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KND90348.1 - 2.6e-20 72.2 13.3 2.6e-20 72.2 13.3 8.3 6 3 4 10 10 10 1 TATA element modulatory factor 1 DNA binding GAS PF13851.6 KND90348.1 - 0.00086 18.7 4.7 0.00086 18.7 4.7 5.1 3 1 2 5 5 5 2 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 KND90348.1 - 0.0056 16.9 2.8 0.0056 16.9 2.8 6.5 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) Holin_BhlA PF10960.8 KND90348.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.1 3 0 0 3 3 3 0 BhlA holin family FlaC_arch PF05377.11 KND90348.1 - 2.9 8.3 0.0 2.9 8.3 0.0 7.0 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) MMS1_N PF10433.9 KND90349.1 - 6e-63 213.2 0.0 6.8e-62 209.7 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KND90349.1 - 0.0031 16.9 0.0 0.014 14.7 0.0 2.0 2 1 0 2 2 2 1 CPSF A subunit region SSP160 PF06933.11 KND90350.1 - 0.19 9.9 1.1 0.29 9.3 1.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GST_C_2 PF13410.6 KND90352.1 - 1.2e-05 25.2 0.5 1.8e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KND90352.1 - 0.00011 22.7 0.0 0.00017 22.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-C2H2 PF00096.26 KND90353.1 - 2.2e-05 24.7 9.5 0.0022 18.3 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KND90353.1 - 0.00061 20.4 1.4 0.0019 18.8 0.1 2.2 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KND90353.1 - 0.0016 19.1 7.6 0.052 14.4 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND90353.1 - 0.016 15.6 1.1 0.016 15.6 1.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 KND90353.1 - 0.063 13.7 6.6 0.37 11.3 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Integrin_B_tail PF07965.12 KND90353.1 - 0.068 13.7 0.4 0.17 12.4 0.2 1.7 1 1 0 1 1 1 0 Integrin beta tail domain zf-C2H2_aberr PF17017.5 KND90353.1 - 0.37 10.9 2.0 0.2 11.8 0.3 1.4 2 0 0 2 2 2 0 Aberrant zinc-finger Tmemb_cc2 PF10267.9 KND90353.1 - 1.1 8.4 4.7 1.4 8.0 4.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Nop PF01798.18 KND90354.1 - 2.3e-71 239.9 0.0 3.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KND90354.1 - 1.7e-45 154.8 1.3 4.8e-45 153.4 1.3 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain TraT PF05818.12 KND90354.1 - 1.5 8.4 5.2 0.83 9.3 2.5 1.9 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein TPR_14 PF13428.6 KND90355.1 - 9.4e-22 75.9 22.8 0.004 17.9 0.2 10.1 8 3 4 12 12 11 6 Tetratricopeptide repeat HAT PF02184.16 KND90355.1 - 1.2e-21 76.3 56.5 7e-13 48.3 1.0 11.4 14 0 0 14 14 14 4 HAT (Half-A-TPR) repeat Suf PF05843.14 KND90355.1 - 1.2e-17 64.8 12.2 0.0026 17.8 0.1 6.6 3 3 1 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KND90355.1 - 8.1e-17 61.5 0.1 3.7e-05 24.2 0.0 6.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 KND90355.1 - 6.8e-07 29.8 6.8 1 10.1 0.1 6.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KND90355.1 - 5.8e-06 25.7 14.1 0.57 9.4 0.1 5.4 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 KND90355.1 - 1.6e-05 24.7 0.3 11 6.6 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND90355.1 - 0.00022 21.6 13.8 33 5.4 0.5 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 KND90355.1 - 0.00026 21.2 1.3 11 6.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KND90355.1 - 0.0023 18.0 6.5 1 9.6 0.2 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND90355.1 - 0.0023 17.9 17.0 2.4 8.5 0.0 7.5 10 0 0 10 10 9 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KND90355.1 - 0.1 12.7 26.0 3 8.0 0.9 7.1 5 2 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 KND90355.1 - 0.22 11.4 4.3 63 3.6 0.5 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND90355.1 - 0.28 11.3 6.9 15 5.7 0.3 5.7 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.10 KND90355.1 - 0.48 9.5 26.1 4.2 6.4 7.6 5.8 3 3 1 4 4 4 0 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 KND90355.1 - 0.68 9.9 21.1 0.92 9.5 0.8 6.7 5 2 3 8 8 8 0 Mad3/BUB1 homology region 1 Fungal_trans PF04082.18 KND90356.1 - 8.1e-19 67.7 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90356.1 - 1.2e-08 34.9 9.9 1.2e-08 34.9 9.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5053 PF16476.5 KND90357.1 - 0.13 12.0 0.2 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Acetate_kinase PF00871.17 KND90359.1 - 7.3e-87 291.6 0.0 1.1e-86 291.1 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.24 KND90359.1 - 2.3e-32 112.5 26.3 2e-18 66.5 7.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND90359.1 - 2.2e-21 76.2 23.6 1e-14 54.3 13.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 KND90359.1 - 0.062 13.3 10.9 0.16 11.9 3.1 2.7 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) QCR10 PF09796.9 KND90359.1 - 0.42 10.7 2.5 18 5.5 0.1 3.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4131 PF13567.6 KND90359.1 - 2.3 7.8 8.0 1.8 8.2 2.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) SirB PF04247.12 KND90359.1 - 8.4 6.5 7.4 1.3 9.1 1.9 2.3 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Glutaredoxin PF00462.24 KND90360.1 - 2.5e-17 62.8 0.0 1.6e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KND90360.1 - 3.6e-12 46.2 0.0 8.4e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KND90360.1 - 0.0017 18.6 0.0 2.2 8.7 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KND90360.1 - 0.1 13.1 0.0 1.4 9.4 0.0 2.7 2 2 0 2 2 2 0 Thioredoxin-like domain SAP130_C PF16014.5 KND90360.1 - 1.1 8.2 5.2 1.5 7.8 5.2 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Npa1 PF11707.8 KND90361.1 - 5.8e-85 285.6 0.1 2.6e-84 283.5 0.0 2.2 2 1 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KND90361.1 - 1.2e-62 211.1 0.4 1.2e-62 211.1 0.4 2.1 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 DUF455 PF04305.14 KND90361.1 - 0.062 12.8 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Chitin_synth_2 PF03142.15 KND90362.1 - 5.9e-250 830.3 1.6 8e-250 829.9 1.6 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KND90362.1 - 6.1e-75 252.8 0.0 1.9e-74 251.2 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KND90362.1 - 2.8e-15 56.0 0.0 1.2e-14 54.0 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KND90362.1 - 3.2e-12 46.8 3.9 3.2e-12 46.8 3.9 1.9 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 KND90362.1 - 5.1e-12 45.8 0.4 1.2e-08 34.9 0.1 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KND90362.1 - 5e-10 39.6 0.1 2.7e-09 37.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KND90362.1 - 4.9e-05 23.2 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF4164 PF13747.6 KND90362.1 - 0.0075 16.5 0.0 7.3 7.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) RsgA_GTPase PF03193.16 KND90362.1 - 0.0098 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KND90362.1 - 0.014 15.8 0.3 0.049 14.0 0.1 2.0 2 0 0 2 2 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KND90362.1 - 0.018 15.1 0.1 0.94 9.6 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 KND90362.1 - 0.055 13.2 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KND90362.1 - 0.065 13.6 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 KND90362.1 - 0.065 13.7 0.5 0.19 12.2 0.1 1.9 2 0 0 2 2 1 0 ABC transporter AAA_22 PF13401.6 KND90362.1 - 0.069 13.4 0.1 0.33 11.2 0.1 2.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KND90362.1 - 0.19 11.8 2.0 6.7 6.7 0.2 2.8 3 0 0 3 3 3 0 Dynamin family AAA_23 PF13476.6 KND90362.1 - 0.21 12.1 0.1 0.5 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 KND90363.1 - 1.3e-66 225.6 0.0 1.5e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Inhibitor_I9 PF05922.16 KND90365.1 - 1.6e-10 41.5 4.2 1.6e-10 41.5 0.0 2.3 2 1 0 2 2 2 1 Peptidase inhibitor I9 p450 PF00067.22 KND90366.1 - 2.7e-50 171.5 0.0 9.4e-50 169.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Atrophin-1 PF03154.15 KND90366.1 - 0.034 12.5 1.3 0.046 12.0 1.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Caps_synth_CapC PF14102.6 KND90366.1 - 0.069 13.6 0.3 0.14 12.6 0.3 1.4 1 0 0 1 1 1 0 Capsule biosynthesis CapC Chitin_synth_2 PF03142.15 KND90367.1 - 2e-228 759.3 0.2 2.8e-228 758.8 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 KND90367.1 - 2.8e-15 56.0 1.8 2.2e-14 53.1 3.2 1.8 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KND90367.1 - 1.5e-14 53.9 0.5 5.6e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KND90367.1 - 8.7e-14 51.9 1.6 8.7e-14 51.9 1.6 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND90367.1 - 1.9e-11 44.3 0.0 8.9e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 KND90367.1 - 5.4e-07 28.2 0.0 8.8e-07 27.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 KND90367.1 - 0.00052 19.5 0.2 0.0054 16.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KND90367.1 - 0.00055 19.8 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.9 KND90368.1 - 7.1e-45 152.8 0.0 9.1e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KND90368.1 - 2.3e-09 37.7 0.0 7.2e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KND90368.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Pkinase PF00069.25 KND90369.1 - 8.3e-67 225.3 0.0 1.1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90369.1 - 4.3e-41 140.9 0.0 5.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND90369.1 - 4.6e-06 26.2 0.0 1.1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KND90369.1 - 6.9e-05 22.3 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KND90369.1 - 0.0026 17.4 0.1 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KND90369.1 - 0.011 15.3 0.0 0.033 13.8 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 KND90369.1 - 0.054 13.4 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KND90369.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KND90369.1 - 0.69 8.6 3.2 0.83 8.4 3.2 1.4 1 1 0 1 1 1 0 Fungal protein kinase Yip1 PF04893.17 KND90370.1 - 7.6e-12 45.3 17.4 1.2e-11 44.6 17.4 1.4 1 1 0 1 1 1 1 Yip1 domain G6PD_C PF02781.16 KND90371.1 - 1.4e-114 382.2 0.0 2.1e-114 381.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KND90371.1 - 1.4e-60 205.0 0.0 2.5e-60 204.1 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.25 KND90372.1 - 4.5e-10 39.3 0.0 8.4e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90372.1 - 3.1e-07 30.0 0.0 5.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND90372.1 - 3.2e-05 24.0 0.2 0.00035 20.6 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND90372.1 - 0.00066 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND90372.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family La PF05383.17 KND90373.1 - 2e-17 63.0 0.0 3.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KND90373.1 - 2.8e-07 30.3 0.1 4.9e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.11 KND90373.1 - 9.4 4.9 8.3 18 4.0 8.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MFS_1 PF07690.16 KND90374.1 - 2.3e-38 132.1 26.8 2.3e-38 132.1 26.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND90374.1 - 6.3e-10 38.5 0.4 6.3e-10 38.5 0.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND90374.1 - 0.00059 18.4 1.8 0.00087 17.8 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) tRNA-synt_2 PF00152.20 KND90375.1 - 5.9e-72 242.4 0.0 8.7e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 KND90375.1 - 1.5e-13 50.4 0.1 2.2e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 KND90375.1 - 0.00057 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.13 KND90376.1 - 2.4e-41 141.9 0.0 3.7e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KND90376.1 - 2.8e-05 23.2 0.6 0.00011 21.3 0.6 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 KND90376.1 - 0.00044 19.8 0.0 0.68 9.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KND90376.1 - 0.00091 19.1 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KND90376.1 - 0.003 18.2 4.5 0.003 18.2 4.5 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 KND90377.1 - 0.00073 18.9 0.7 0.18 11.0 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Inositol_P PF00459.25 KND90378.1 - 2e-60 204.6 0.0 2.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family COX6A PF02046.15 KND90379.1 - 2.1e-44 150.5 1.0 2.7e-44 150.2 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 KND90380.1 - 1.6e-09 37.7 0.1 2.8e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CIA30 PF08547.12 KND90381.1 - 1e-43 149.1 0.0 1.2e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ANAPC5 PF12862.7 KND90382.1 - 2e-32 111.1 5.7 3.5e-32 110.3 2.8 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 KND90382.1 - 0.7 10.1 5.3 3 8.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND90382.1 - 6 6.9 10.9 23 5.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MATalpha_HMGbox PF04769.12 KND90383.1 - 1.5e-62 210.5 0.0 2.1e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 KND90384.1 - 8.2e-80 267.7 0.0 8.2e-80 267.7 0.0 2.4 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 KND90384.1 - 3.4e-54 183.2 10.3 3.4e-54 183.2 10.3 6.2 4 1 2 6 6 6 2 I/LWEQ domain ENTH PF01417.20 KND90384.1 - 0.041 13.9 0.0 0.25 11.4 0.0 2.5 1 0 0 1 1 1 0 ENTH domain Surfac_D-trimer PF09006.11 KND90384.1 - 0.65 9.9 4.9 0.3 11.0 0.9 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation HMG_box PF00505.19 KND90385.1 - 9.9e-18 64.3 2.4 1.5e-17 63.8 2.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND90385.1 - 3e-07 30.9 1.3 4e-07 30.5 0.5 1.6 2 0 0 2 2 2 1 HMG-box domain MAT1-1-2 PF17043.5 KND90386.1 - 3.9e-40 137.3 0.1 5.9e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function RRM_1 PF00076.22 KND90387.1 - 1.4e-18 66.5 0.0 6.4e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim44 PF04280.15 KND90388.1 - 2.3e-06 27.8 0.0 4.9e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Tim44-like domain Mo-co_dimer PF03404.16 KND90389.1 - 2.5e-59 199.2 0.2 5.5e-59 198.1 0.2 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KND90389.1 - 5.6e-55 185.6 0.0 8.9e-55 184.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KND90389.1 - 1.6e-34 118.2 0.0 2.8e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND90389.1 - 5e-28 97.9 0.0 1.1e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KND90389.1 - 4.7e-18 65.1 0.0 9.3e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KND90389.1 - 0.013 15.6 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain DEAD PF00270.29 KND90390.1 - 2.8e-27 95.6 0.0 5.1e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KND90390.1 - 1.3e-22 80.3 0.4 5.5e-22 78.3 0.4 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 KND90390.1 - 8.2e-11 42.2 0.0 2.4e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90390.1 - 3.5e-07 30.4 0.0 6.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KND90390.1 - 2.1e-05 24.9 0.0 4.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like Ran_BP1 PF00638.18 KND90391.1 - 1.9e-15 57.2 0.5 3.5e-07 30.5 0.2 2.2 2 0 0 2 2 2 2 RanBP1 domain DUF1223 PF06764.11 KND90391.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) eIF3_subunit PF08597.10 KND90392.1 - 2.8e-74 250.1 25.3 3.5e-74 249.8 25.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF1955 PF09205.10 KND90392.1 - 0.063 13.0 0.4 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) IHABP4_N PF16174.5 KND90392.1 - 2.4 8.8 23.4 0.33 11.5 13.8 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal FAM60A PF15396.6 KND90392.1 - 7.8 6.4 10.3 1.6 8.7 3.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A AOX PF01786.17 KND90393.1 - 6.5e-90 300.4 0.2 8.9e-90 300.0 0.2 1.2 1 0 0 1 1 1 1 Alternative oxidase Enolase_C PF00113.22 KND90394.1 - 7.5e-153 508.0 0.1 9.9e-153 507.6 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KND90394.1 - 2.1e-57 192.9 0.2 3.6e-57 192.2 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KND90394.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KND90394.1 - 0.0014 17.9 0.6 0.14 11.3 0.2 2.8 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus KH_8 PF17903.1 KND90395.1 - 9e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KND90395.1 - 0.02 14.7 0.4 0.039 13.8 0.4 1.5 1 0 0 1 1 1 0 KH domain AP_endonuc_2 PF01261.24 KND90396.1 - 6.3e-28 97.6 0.1 1e-27 97.0 0.1 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Apidaecin PF00807.17 KND90396.1 - 0.22 11.6 0.5 0.51 10.5 0.5 1.5 1 0 0 1 1 1 0 Apidaecin Mad3_BUB1_I PF08311.12 KND90397.1 - 9.5e-43 145.1 0.3 1.7e-42 144.3 0.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KND90397.1 - 5.2e-09 35.9 0.0 3e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KND90397.1 - 4e-06 26.9 0.0 1.4e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 KND90397.1 - 3.5e-05 23.2 0.1 0.00017 21.0 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 KND90397.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein PI3K_1B_p101 PF10486.9 KND90397.1 - 0.52 8.0 7.9 0.73 7.5 7.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-H2C2_2 PF13465.6 KND90398.1 - 3.4e-12 46.2 17.5 3.7e-06 27.1 2.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KND90398.1 - 7.4e-11 41.9 23.6 0.002 18.5 8.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND90398.1 - 6.3e-07 29.7 19.7 0.02 15.7 6.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KND90398.1 - 0.00098 18.9 2.5 0.2 11.5 0.3 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KND90398.1 - 0.0018 18.2 18.0 0.13 12.3 0.1 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_9 PF16293.5 KND90398.1 - 0.018 14.9 3.3 2.3 8.2 0.2 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 KND90398.1 - 0.018 15.2 5.5 0.11 12.6 2.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 KND90398.1 - 0.021 15.1 11.9 0.047 14.0 6.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 KND90398.1 - 0.036 14.1 2.8 2 8.5 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger domain bZIP_1 PF00170.21 KND90398.1 - 0.037 14.1 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor zf-C2H2_jaz PF12171.8 KND90398.1 - 0.085 13.2 9.8 0.94 9.8 3.8 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KND90398.1 - 0.15 12.0 6.4 0.52 10.3 0.9 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain DZR PF12773.7 KND90398.1 - 0.22 11.6 6.6 1.7 8.7 6.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon FYDLN_acid PF09538.10 KND90398.1 - 0.41 11.3 4.7 4.9 7.9 0.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.6 KND90398.1 - 0.43 10.5 6.2 0.23 11.4 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3268 PF11672.8 KND90398.1 - 0.81 10.0 2.8 3.4 8.0 2.8 1.9 1 1 1 2 2 2 0 zinc-finger-containing domain TF_Zn_Ribbon PF08271.12 KND90398.1 - 1.1 8.8 4.6 2.6 7.6 1.4 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 KND90398.1 - 1.2 9.5 6.1 18 5.7 0.1 3.1 2 1 1 3 3 3 0 zinc-ribbon zf-BED PF02892.15 KND90398.1 - 1.5 8.9 8.6 0.86 9.7 4.1 2.5 1 1 1 2 2 2 0 BED zinc finger HypA PF01155.19 KND90398.1 - 1.8 8.6 3.2 5.7 7.0 3.2 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 KND90398.1 - 3.3 7.8 8.4 8 6.5 3.3 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 KND90398.1 - 4.4 7.2 6.7 2.8 7.8 1.0 3.0 1 1 2 3 3 3 0 GAGA factor zinc_ribbon_4 PF13717.6 KND90398.1 - 4.6 7.2 5.7 31 4.6 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KND90398.1 - 6.1 6.9 6.0 35 4.5 6.0 2.1 1 1 0 1 1 1 0 zinc-ribbons zf-UDP PF14569.6 KND90398.1 - 6.6 6.9 9.1 6.7 6.9 0.5 2.8 1 1 0 2 2 2 0 Zinc-binding RING-finger zf-met PF12874.7 KND90398.1 - 7.1 7.2 10.7 15 6.1 2.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DAGAT PF03982.13 KND90399.1 - 4.2e-96 321.4 0.0 5.4e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Hist_deacetyl PF00850.19 KND90400.1 - 1.4e-79 267.8 0.0 1.9e-79 267.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SUN PF03856.13 KND90401.1 - 2.2e-93 312.3 8.8 2.7e-93 312.0 8.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CBF PF03914.17 KND90402.1 - 3.6e-48 163.8 0.4 3.6e-48 163.8 0.4 2.4 3 0 0 3 3 3 1 CBF/Mak21 family CNOT1_TTP_bind PF16417.5 KND90402.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Cnd1 PF12717.7 KND90402.1 - 0.12 12.4 0.5 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HGTP_anticodon PF03129.20 KND90403.1 - 1.2e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KND90403.1 - 2e-09 37.7 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) TRAM_LAG1_CLN8 PF03798.16 KND90404.1 - 7.1e-49 166.2 15.9 1.1e-48 165.6 15.9 1.3 1 0 0 1 1 1 1 TLC domain A_deaminase PF00962.22 KND90405.1 - 3.5e-121 404.6 0.1 5e-121 404.0 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KND90405.1 - 6.4e-74 248.9 6.2 1.1e-43 149.6 1.9 2.2 1 1 1 2 2 2 2 UAA transporter family SHD1 PF03983.12 KND90405.1 - 3.3e-35 119.7 0.0 6e-35 118.9 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 KND90405.1 - 1.2e-30 104.9 10.4 3.3e-12 45.8 0.5 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 KND90405.1 - 6.4e-27 93.2 11.7 7.9e-13 48.1 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 KND90405.1 - 7.5e-21 73.6 0.1 9.7e-09 34.8 0.0 4.4 4 0 0 4 4 4 2 Variant SH3 domain SAM_4 PF18017.1 KND90405.1 - 1.9e-05 24.5 0.0 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 KND90405.1 - 1.4 9.2 4.1 57 4.1 0.5 3.4 3 0 0 3 3 3 0 Bacterial SH3 domain HMG_box PF00505.19 KND90406.1 - 3.2e-10 40.3 0.4 8.3e-10 38.9 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND90406.1 - 0.00063 20.3 0.2 0.0016 19.0 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KND90406.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box PHD PF00628.29 KND90407.1 - 3.7e-08 33.1 7.7 7.3e-08 32.2 7.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KND90407.1 - 0.011 15.3 5.4 0.022 14.3 5.4 1.5 1 0 0 1 1 1 0 PHD-finger Ion_trans PF00520.31 KND90408.1 - 1.8e-120 400.7 77.1 4.6e-37 127.6 0.8 4.8 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 KND90408.1 - 0.0014 17.4 0.6 0.0014 17.4 0.6 7.6 7 2 1 8 8 8 5 Polycystin cation channel EF-hand_7 PF13499.6 KND90408.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair WD40 PF00400.32 KND90410.1 - 3.3e-12 46.7 3.5 0.23 12.4 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90410.1 - 0.037 14.3 0.1 4.8 7.5 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MutS_V PF00488.21 KND90412.1 - 5.7e-46 156.9 0.0 9.5e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND90412.1 - 1.1e-15 58.4 0.3 2.7e-15 57.1 0.0 1.8 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 KND90412.1 - 0.0087 16.4 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 1 MutS family domain IV YfcL PF08891.11 KND90412.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 YfcL protein AAA_14 PF13173.6 KND90412.1 - 0.19 11.8 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMgT PF10270.9 KND90413.1 - 2.2e-35 121.0 0.0 2.8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter RIC1 PF07064.13 KND90414.1 - 8.4e-92 307.1 0.1 1.2e-91 306.6 0.1 1.3 1 0 0 1 1 1 1 RIC1 CK_II_beta PF01214.18 KND90414.1 - 1.3e-74 250.0 0.2 2e-74 249.4 0.2 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L2_C PF03947.18 KND90415.1 - 1.7e-51 173.7 5.1 4.1e-51 172.4 5.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KND90415.1 - 1.4e-23 82.6 0.5 2.9e-23 81.6 0.5 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain F-box-like PF12937.7 KND90416.1 - 0.026 14.4 0.0 0.089 12.7 0.0 2.0 1 0 0 1 1 1 0 F-box-like DM PF00751.18 KND90416.1 - 0.16 11.9 0.9 0.34 10.9 0.9 1.5 1 0 0 1 1 1 0 DM DNA binding domain Dynamin_M PF01031.20 KND90417.1 - 4e-109 364.2 0.0 6.7e-109 363.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KND90417.1 - 3e-56 190.1 0.0 5.5e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KND90417.1 - 1.9e-30 104.9 1.4 3.8e-30 103.9 1.4 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KND90417.1 - 4.4e-05 23.5 0.2 0.0006 19.9 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PLA2_B PF01735.18 KND90418.1 - 3.2e-30 105.0 0.0 5.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain APS_kinase PF01583.20 KND90421.1 - 6.6e-72 240.6 0.0 9.7e-72 240.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KND90421.1 - 5.8e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KND90421.1 - 2.8e-05 24.7 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KND90421.1 - 0.00021 20.8 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 KND90421.1 - 0.0069 16.8 0.1 0.01 16.2 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KND90421.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF463 PF04317.12 KND90421.1 - 0.055 12.4 0.0 0.068 12.1 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.6 KND90421.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 KND90421.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 KND90421.1 - 0.18 10.9 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit V-ATPase_C PF03223.15 KND90422.1 - 1.3e-117 393.3 0.0 1.7e-117 393.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 KND90422.1 - 0.1 13.2 0.4 0.23 12.1 0.1 1.7 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain AT_hook PF02178.19 KND90423.1 - 0.48 10.5 23.9 1.3 9.1 0.5 4.7 3 0 0 3 3 3 0 AT hook motif MFS_1 PF07690.16 KND90424.1 - 3e-28 98.8 28.7 6e-28 97.8 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KND90424.1 - 0.088 13.0 5.6 0.97 9.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) p450 PF00067.22 KND90425.1 - 2.7e-66 224.2 0.0 3.1e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APA3_viroporin PF11289.8 KND90425.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Coronavirus accessory protein 3a AMP-binding PF00501.28 KND90426.1 - 2.4e-82 276.8 0.0 3.8e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.18 KND90426.1 - 2.5e-12 46.4 0.4 2.5e-12 46.4 0.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain AMP-binding_C PF13193.6 KND90426.1 - 3.3e-11 44.0 0.2 7.7e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KND90427.1 - 2.9e-83 279.8 0.0 4e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND90427.1 - 1.4e-13 51.6 0.1 3.4e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NPR3 PF03666.13 KND90428.1 - 6.1e-142 473.7 0.0 9.9e-142 473.0 0.0 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 TMEM190 PF15431.6 KND90428.1 - 0.1 12.7 0.5 0.19 11.9 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 Pkinase PF00069.25 KND90429.1 - 3.1e-60 203.8 0.0 1.9e-37 129.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND90429.1 - 1.1e-27 97.0 0.0 3.3e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KND90429.1 - 1.5e-15 57.3 0.0 3.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KND90429.1 - 4.5e-06 26.2 0.0 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KND90429.1 - 0.00031 20.8 0.1 0.02 14.8 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND90429.1 - 0.012 14.6 0.1 0.021 13.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PAS_9 PF13426.7 KND90429.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain Kdo PF06293.14 KND90429.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KND90429.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Aminotran_1_2 PF00155.21 KND90430.1 - 8.4e-18 64.7 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KND90430.1 - 4.3e-07 29.1 0.0 8.9e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 KND90430.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PAP2 PF01569.21 KND90431.1 - 8.7e-21 74.1 2.7 8.7e-21 74.1 2.7 2.7 2 1 0 2 2 2 1 PAP2 superfamily Mn_catalase PF05067.12 KND90431.1 - 0.15 11.0 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Manganese containing catalase Amino_oxidase PF01593.24 KND90432.1 - 2.1e-23 83.3 0.1 4e-23 82.4 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND90432.1 - 1.8e-12 47.3 0.0 1.2e-11 44.7 0.1 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND90432.1 - 3.3e-09 36.8 3.2 1.1e-06 28.5 0.4 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND90432.1 - 0.00071 18.9 0.1 0.012 14.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND90432.1 - 0.00088 19.8 0.2 0.43 11.2 0.0 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND90432.1 - 0.0018 18.3 0.6 0.026 14.5 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KND90432.1 - 0.0094 15.2 0.1 0.016 14.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KND90432.1 - 0.019 13.8 0.1 0.027 13.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 KND90432.1 - 0.44 9.7 2.1 1.4 8.1 0.5 2.0 2 0 0 2 2 2 0 FAD binding domain Med14 PF08638.11 KND90433.1 - 1.3e-66 223.7 0.0 2.3e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 p450 PF00067.22 KND90434.1 - 7.1e-61 206.3 0.0 1.1e-60 205.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH_2 PF14608.6 KND90435.1 - 2.2e-15 56.5 57.3 1.2e-05 25.6 11.8 5.6 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KND90435.1 - 0.0021 18.3 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HLH PF00010.26 KND90436.1 - 3e-12 46.3 0.0 1.4e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 KND90437.1 - 5.1e-34 117.1 16.1 6.6e-34 116.7 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.17 KND90438.1 - 3.4e-18 65.4 0.1 5.7e-18 64.7 0.1 1.3 1 0 0 1 1 1 1 La domain Sugar_tr PF00083.24 KND90439.1 - 4.5e-23 81.8 27.1 7.3e-14 51.5 9.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2686 PF10887.8 KND90439.1 - 0.15 10.9 0.0 0.42 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2686) DUF3611 PF12263.8 KND90439.1 - 1.2 9.1 8.2 0.043 13.7 1.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Med9 PF07544.13 KND90441.1 - 0.096 12.8 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Choline_kinase PF01633.20 KND90442.1 - 1.7e-48 165.1 0.0 3.5e-48 164.0 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 KND90442.1 - 7.9e-10 39.1 0.1 1.3e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KND90442.1 - 0.0063 15.4 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 KND90442.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase eIF-3_zeta PF05091.12 KND90444.1 - 2.3e-198 660.4 0.0 2.9e-198 660.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SH3_9 PF14604.6 KND90445.1 - 6e-24 83.7 4.2 1.7e-12 47.0 0.4 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 KND90445.1 - 1.1e-19 69.8 8.1 1e-10 41.1 0.6 3.4 3 0 0 3 3 3 2 SH3 domain Cofilin_ADF PF00241.20 KND90445.1 - 4.5e-16 58.8 0.0 1e-15 57.6 0.0 1.6 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KND90445.1 - 1.1e-11 44.2 0.0 1.1e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF2868 PF11067.8 KND90445.1 - 4.5 6.7 5.5 3.6 7.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) Chitin_synth_2 PF03142.15 KND90446.1 - 6.9e-23 81.1 4.6 5.6e-21 74.8 3.5 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KND90446.1 - 2e-15 57.2 5.2 2e-15 57.2 5.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND90446.1 - 2.8e-10 40.5 0.0 9.1e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KND90446.1 - 0.00072 19.4 0.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 zf-C2H2 PF00096.26 KND90448.1 - 2e-13 50.0 12.5 3.6e-06 27.1 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND90448.1 - 5.9e-13 48.6 8.1 1.9e-07 31.2 0.2 4.0 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND90448.1 - 5.6e-09 36.1 11.5 0.0004 21.0 1.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND90448.1 - 1e-07 31.8 7.9 0.00032 20.6 0.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KND90448.1 - 4.5e-05 23.7 1.7 0.013 15.8 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 KND90448.1 - 0.0075 16.0 5.4 0.41 10.5 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KND90448.1 - 0.088 13.1 0.1 0.088 13.1 0.1 4.4 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.6 KND90448.1 - 0.1 13.1 0.8 0.23 12.0 0.8 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 KND90448.1 - 0.16 12.5 2.0 5.7 7.5 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 KND90448.1 - 0.53 10.6 3.8 17 5.7 0.1 2.4 1 1 1 2 2 2 0 LIM domain FYVE PF01363.21 KND90448.1 - 3.4 7.9 5.6 6.8 6.9 5.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger MFS_1 PF07690.16 KND90450.1 - 6.4e-36 124.0 28.5 9.8e-36 123.4 28.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4734 PF15881.5 KND90451.1 - 0.053 13.7 0.2 0.092 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) Fungal_trans_2 PF11951.8 KND90452.1 - 1.8e-07 30.3 1.9 0.0062 15.4 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90452.1 - 0.00011 22.2 5.5 0.00022 21.2 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KND90455.1 - 3.2e-11 43.6 0.0 6.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND90455.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase A_deaminase PF00962.22 KND90456.1 - 7e-65 219.5 0.0 8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase zf-AN1 PF01428.16 KND90457.1 - 0.00077 19.6 6.3 0.0017 18.4 6.3 1.6 1 0 0 1 1 1 1 AN1-like Zinc finger WD40 PF00400.32 KND90459.1 - 1.8e-20 72.8 4.7 2.2e-06 28.3 0.1 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90459.1 - 2e-11 44.0 0.0 0.092 13.1 0.0 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND90459.1 - 0.011 14.4 1.2 0.19 10.3 0.0 2.3 2 1 0 3 3 3 0 Nucleoporin Nup120/160 eIF2A PF08662.11 KND90459.1 - 0.031 14.2 0.0 0.81 9.5 0.0 3.0 2 2 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 KND90459.1 - 0.066 12.1 0.1 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cyclin_N PF00134.23 KND90460.1 - 2.2e-43 147.1 0.1 4.1e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KND90460.1 - 2.9e-33 114.5 0.0 4.9e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain p450 PF00067.22 KND90461.1 - 4.4e-68 230.1 0.0 1.3e-67 228.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Flavodoxin_1 PF00258.25 KND90461.1 - 1.7e-26 93.2 0.0 1.7e-25 89.9 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 KND90461.1 - 2e-20 73.4 0.1 1.2e-17 64.3 0.1 2.4 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 KND90461.1 - 5.1e-12 46.4 0.0 2.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 KND90461.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain PT-TG PF14449.6 KND90461.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Pre-toxin TG zf-RING_2 PF13639.6 KND90462.1 - 6e-13 48.9 17.4 9.5e-13 48.3 7.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND90462.1 - 1.5e-10 40.7 11.7 4.8e-08 32.7 4.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND90462.1 - 1.6e-09 37.3 4.4 1.6e-09 37.3 4.4 2.2 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND90462.1 - 2.1e-08 33.8 7.2 2.1e-08 33.8 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90462.1 - 4.2e-08 32.9 16.1 3.1e-06 26.9 7.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND90462.1 - 2.9e-07 30.7 5.9 2.9e-07 30.7 5.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND90462.1 - 2.4e-05 24.1 10.8 0.00017 21.3 3.9 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND90462.1 - 2.7e-05 24.0 5.0 2.7e-05 24.0 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND90462.1 - 5.2e-05 23.2 6.7 5.2e-05 23.2 0.8 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KND90462.1 - 0.0015 18.5 2.0 0.0015 18.5 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KND90462.1 - 0.0039 17.2 3.2 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KND90462.1 - 0.0044 17.1 2.1 0.075 13.2 0.6 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 KND90462.1 - 0.028 14.7 7.6 0.031 14.5 3.9 2.4 2 0 0 2 2 2 0 zinc-ribbon DNA_ligase_ZBD PF03119.16 KND90462.1 - 0.045 13.8 3.3 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 KND90462.1 - 0.063 13.3 8.7 0.56 10.2 0.5 2.6 2 1 0 2 2 2 0 zinc-ribbons Baculo_RING PF05883.11 KND90462.1 - 0.3 11.1 1.9 1.3 9.0 1.0 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 KND90462.1 - 0.33 11.1 13.1 0.42 10.8 1.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KND90462.1 - 0.74 9.7 13.2 0.16 11.8 4.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KND90462.1 - 0.77 9.7 12.3 3.3 7.7 1.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.29 KND90462.1 - 1 9.3 13.7 1.8 8.5 5.6 2.6 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KND90462.1 - 1.1 8.9 14.9 0.12 12.1 5.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KND90462.1 - 1.3 9.1 7.3 2.4 8.3 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KND90462.1 - 1.7 8.6 4.2 3.8 7.4 4.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 KND90462.1 - 2.1 8.5 8.3 12 6.1 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PhnA_Zn_Ribbon PF08274.12 KND90462.1 - 4.1 7.5 6.0 27 4.8 0.5 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-P11 PF03854.14 KND90462.1 - 5.8 6.7 10.4 0.067 12.9 2.4 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_2 PF13639.6 KND90463.1 - 6e-13 48.9 17.4 9.5e-13 48.3 7.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND90463.1 - 1.5e-10 40.7 11.7 4.8e-08 32.7 4.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND90463.1 - 1.6e-09 37.3 4.4 1.6e-09 37.3 4.4 2.2 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND90463.1 - 2.1e-08 33.8 7.2 2.1e-08 33.8 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90463.1 - 4.2e-08 32.9 16.1 3.1e-06 26.9 7.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND90463.1 - 2.9e-07 30.7 5.9 2.9e-07 30.7 5.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND90463.1 - 2.4e-05 24.1 10.8 0.00017 21.3 3.9 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND90463.1 - 2.7e-05 24.0 5.0 2.7e-05 24.0 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND90463.1 - 5.2e-05 23.2 6.7 5.2e-05 23.2 0.8 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KND90463.1 - 0.0015 18.5 2.0 0.0015 18.5 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger HypA PF01155.19 KND90463.1 - 0.0039 17.2 3.2 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 KND90463.1 - 0.0044 17.1 2.1 0.075 13.2 0.6 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 KND90463.1 - 0.028 14.7 7.6 0.031 14.5 3.9 2.4 2 0 0 2 2 2 0 zinc-ribbon DNA_ligase_ZBD PF03119.16 KND90463.1 - 0.045 13.8 3.3 2.5 8.2 0.4 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zinc-ribbons_6 PF07191.12 KND90463.1 - 0.063 13.3 8.7 0.56 10.2 0.5 2.6 2 1 0 2 2 2 0 zinc-ribbons Baculo_RING PF05883.11 KND90463.1 - 0.3 11.1 1.9 1.3 9.0 1.0 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.6 KND90463.1 - 0.33 11.1 13.1 0.42 10.8 1.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KND90463.1 - 0.74 9.7 13.2 0.16 11.8 4.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KND90463.1 - 0.77 9.7 12.3 3.3 7.7 1.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.29 KND90463.1 - 1 9.3 13.7 1.8 8.5 5.6 2.6 2 0 0 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 KND90463.1 - 1.1 8.9 14.9 0.12 12.1 5.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KND90463.1 - 1.3 9.1 7.3 2.4 8.3 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-Nse PF11789.8 KND90463.1 - 1.7 8.6 4.2 3.8 7.4 4.2 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 KND90463.1 - 2.1 8.5 8.3 12 6.1 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) PhnA_Zn_Ribbon PF08274.12 KND90463.1 - 4.1 7.5 6.0 27 4.8 0.5 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf-P11 PF03854.14 KND90463.1 - 5.8 6.7 10.4 0.067 12.9 2.4 1.9 2 0 0 2 2 2 0 P-11 zinc finger Pkinase PF00069.25 KND90464.1 - 9.4e-05 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND90464.1 - 0.0016 18.4 7.0 0.0024 17.9 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KND90464.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KND90464.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase SRP-alpha_N PF04086.13 KND90464.1 - 9.4 6.1 8.4 13 5.7 1.5 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal eIF3_subunit PF08597.10 KND90464.1 - 9.7 6.0 8.7 0.5 10.2 2.5 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Methyltransf_25 PF13649.6 KND90466.1 - 1.3e-09 38.6 0.0 2.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90466.1 - 1.7e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND90466.1 - 1.1e-07 31.4 0.0 1.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KND90466.1 - 1.2e-07 32.4 0.0 2.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND90466.1 - 3.5e-06 27.0 0.0 5.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND90466.1 - 7.7e-06 25.6 0.0 1.9e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KND90466.1 - 1.3e-05 25.8 0.0 3.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND90466.1 - 0.00026 20.5 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_PK PF05891.12 KND90466.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 KND90466.1 - 0.016 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase DOT1 PF08123.13 KND90466.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 KND90466.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ank_2 PF12796.7 KND90467.1 - 5.8e-81 267.1 0.5 3.6e-19 69.1 0.0 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND90467.1 - 4.9e-46 149.4 0.1 0.00031 21.0 0.0 10.0 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 KND90467.1 - 8e-44 146.2 0.1 0.00096 19.5 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KND90467.1 - 6.9e-42 141.3 5.2 7.6e-10 39.1 0.0 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND90467.1 - 7.3e-36 121.8 1.0 1.8e-06 28.1 0.0 8.7 3 2 6 9 9 9 8 Ankyrin repeats (many copies) AAA_16 PF13191.6 KND90467.1 - 2.9e-06 27.8 0.0 2.2e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KND90467.1 - 3e-05 24.0 0.0 8.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 KND90467.1 - 0.00046 19.5 0.1 0.00077 18.8 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_22 PF13401.6 KND90467.1 - 0.0019 18.5 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain SpoU_sub_bind PF08032.12 KND90467.1 - 0.002 18.4 0.8 22 5.4 0.0 4.8 5 0 0 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding MMR_HSR1 PF01926.23 KND90467.1 - 0.019 15.0 0.0 0.089 12.9 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 KND90467.1 - 0.032 13.5 1.4 0.51 9.5 0.2 2.2 1 1 0 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.27 KND90467.1 - 0.063 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Lipase_GDSL_2 PF13472.6 KND90467.1 - 0.082 13.3 0.1 22 5.4 0.0 3.1 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family T3SS_HrpK1 PF16937.5 KND90467.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system translocator protein, HrpF AAA_29 PF13555.6 KND90467.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1397 PF07165.11 KND90467.1 - 0.16 11.3 0.2 20 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1397) RNA_helicase PF00910.22 KND90467.1 - 0.18 12.2 0.1 0.4 11.1 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Ribonucleas_3_3 PF14622.6 KND90469.1 - 1.6e-10 41.2 0.0 1.5e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KND90469.1 - 5.9e-06 26.8 0.0 5.3e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 Ribonuclease III domain APH PF01636.23 KND90470.1 - 1.8e-11 44.4 0.1 1.6e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND90470.1 - 2.3e-07 30.6 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND90470.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Chromate_transp PF02417.15 KND90472.1 - 1.1e-52 178.3 36.7 1.4e-32 113.0 15.6 2.5 3 0 0 3 3 3 2 Chromate transporter Methyltransf_23 PF13489.6 KND90473.1 - 3.9e-18 65.8 0.0 5.4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND90473.1 - 6.4e-10 39.6 0.0 1.4e-09 38.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90473.1 - 6.5e-08 33.2 0.0 5.1e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90473.1 - 8.6e-08 32.1 0.0 1.6e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND90473.1 - 1.2e-06 29.1 0.0 2.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND90473.1 - 0.0011 18.5 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 KND90473.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KND90473.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KND90473.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 KND90473.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KND90473.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain zf-CCCH PF00642.24 KND90475.1 - 1.1e-08 34.8 2.7 1.1e-08 34.8 2.7 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KND90475.1 - 1.8e-07 30.9 6.3 3.2e-07 30.1 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND90475.1 - 1.2e-06 28.3 8.2 2.3e-06 27.4 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90475.1 - 1.6e-06 27.9 9.6 2.9e-06 27.1 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND90475.1 - 7.1e-06 26.0 6.0 1.4e-05 25.0 6.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 KND90475.1 - 3.8e-05 23.6 6.2 3.8e-05 23.6 6.2 1.8 2 0 0 2 2 1 1 Zinc finger domain zf-RING_10 PF16685.5 KND90475.1 - 5.5e-05 23.2 3.5 5.5e-05 23.2 3.5 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 KND90475.1 - 0.00012 22.0 8.5 0.00024 21.0 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 KND90475.1 - 0.00026 20.7 2.4 0.00026 20.7 2.4 2.5 3 0 0 3 3 3 1 CCCH-type zinc finger zf-RING_2 PF13639.6 KND90475.1 - 0.0011 19.2 7.7 0.0022 18.3 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KND90475.1 - 0.0062 16.4 5.2 0.013 15.3 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KND90475.1 - 0.3 11.3 7.4 0.75 10.0 7.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 KND90475.1 - 0.35 11.4 4.8 0.92 10.1 4.8 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Harakiri PF15196.6 KND90475.1 - 1 9.8 4.3 0.6 10.6 1.3 2.1 2 0 0 2 2 2 0 Activator of apoptosis harakiri Autophagy_N PF03986.13 KND90476.1 - 1.6e-42 144.7 0.0 3.5e-42 143.6 0.0 1.6 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KND90476.1 - 5.6e-16 57.7 0.6 1.1e-15 56.9 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KND90476.1 - 6.2e-15 55.5 0.1 1.1e-14 54.7 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain MMM1 PF10296.9 KND90477.1 - 5.6e-07 28.9 0.6 0.00028 20.1 0.0 2.3 1 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Mcp5_PH PF12814.7 KND90478.1 - 3.1e-46 156.5 0.1 6.4e-46 155.4 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KND90478.1 - 7.1e-06 26.5 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PH domain RasGAP_C PF03836.15 KND90478.1 - 0.047 13.8 16.2 0.012 15.8 10.9 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Fez1 PF06818.15 KND90478.1 - 4.5 7.7 31.5 1 9.8 15.9 3.5 3 0 0 3 3 3 0 Fez1 Peptidase_S8 PF00082.22 KND90479.1 - 2e-22 79.9 0.1 3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Gp5_C PF06715.12 KND90480.1 - 0.016 15.3 0.3 3.3 8.0 0.3 2.7 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) Aldedh PF00171.22 KND90481.1 - 1.9e-114 382.7 0.6 8.5e-66 222.3 0.0 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family ADH_zinc_N PF00107.26 KND90482.1 - 1.1e-17 64.2 0.2 1.7e-17 63.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND90482.1 - 5.9e-13 48.7 0.4 1.5e-12 47.4 0.4 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 4HBT PF03061.22 KND90484.1 - 1.8e-11 44.2 0.0 4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Patatin PF01734.22 KND90485.1 - 4.8e-27 95.5 0.1 7.4e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Trypsin PF00089.26 KND90486.1 - 0.00044 20.1 0.1 0.00077 19.3 0.1 1.3 1 0 0 1 1 1 1 Trypsin Antimicrobial20 PF08256.11 KND90486.1 - 2.8 8.7 7.9 1.6 9.5 0.3 4.0 3 0 0 3 3 3 0 Aurein-like antibiotic peptide MAGUK_N_PEST PF10608.9 KND90487.1 - 0.016 15.7 0.9 0.12 12.9 0.9 2.1 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Aspzincin_M35 PF14521.6 KND90488.1 - 4.2e-22 79.3 0.5 4.6e-22 79.1 0.5 1.0 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 KND90488.1 - 2.9e-21 75.7 1.9 3e-21 75.7 1.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family DUF2293 PF10056.9 KND90490.1 - 6.2e-28 96.9 0.1 6.2e-28 96.9 0.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) LRR_8 PF13855.6 KND90491.1 - 3.4e-31 106.8 43.1 1.2e-07 31.4 6.2 9.6 3 2 8 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 KND90491.1 - 1.1e-27 95.6 33.8 4.1e-05 23.8 0.1 9.8 7 2 2 10 10 10 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KND90491.1 - 1.5e-06 27.8 17.1 0.023 14.2 0.5 4.7 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KND90491.1 - 8e-06 25.7 28.5 4.4 8.2 0.4 11.9 12 1 1 13 13 13 2 Leucine Rich Repeat LRR_6 PF13516.6 KND90491.1 - 0.0028 17.6 20.5 0.9 9.8 0.5 8.9 9 0 0 9 9 9 1 Leucine Rich repeat Cep57_CLD_2 PF14197.6 KND90493.1 - 0.02 14.9 3.6 0.02 14.9 3.6 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 KND90493.1 - 3.3 8.4 14.6 5.6 7.7 2.2 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 KND90494.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain FTA2 PF13095.6 KND90494.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Alanine_zipper PF11839.8 KND90494.1 - 0.07 13.5 16.3 0.19 12.1 16.3 1.8 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DAO PF01266.24 KND90495.1 - 3e-36 125.7 1.6 3.8e-36 125.4 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND90495.1 - 0.0002 21.4 0.2 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND90495.1 - 0.00032 20.9 0.0 0.00088 19.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND90495.1 - 0.005 16.0 0.0 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KND90495.1 - 0.016 14.5 0.0 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND90495.1 - 0.036 13.1 0.1 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein TBP PF00352.21 KND90496.1 - 9e-67 221.0 0.2 4.4e-32 109.9 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KND90496.1 - 6.7e-05 22.9 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KND90496.1 - 0.041 13.7 0.2 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) UCH_1 PF13423.6 KND90498.1 - 4.3e-104 348.6 0.1 9.8e-104 347.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KND90498.1 - 1e-21 78.2 0.0 2e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease FlaG PF03646.15 KND90498.1 - 0.11 12.7 0.0 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 FlaG protein Methyltransf_25 PF13649.6 KND90499.1 - 2.7e-07 31.2 0.0 4.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90499.1 - 5.2e-06 27.1 0.0 8.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND90499.1 - 0.00067 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90499.1 - 0.0011 18.8 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND90499.1 - 0.0094 15.8 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF3692 PF12469.8 KND90500.1 - 0.17 12.1 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 CRISPR-associated protein OPT PF03169.15 KND90502.1 - 1.2e-157 526.3 47.1 1.4e-157 526.0 47.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YbgT_YccB PF08173.11 KND90502.1 - 6.1 7.1 8.0 0.78 9.9 2.1 2.8 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Zn_clus PF00172.18 KND90503.1 - 0.0027 17.8 0.6 0.0027 17.8 0.6 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 KND90504.1 - 2.2e-41 142.2 0.0 6e-41 140.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KND90505.1 - 4.6e-09 36.2 11.7 7e-09 35.7 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND90505.1 - 0.00047 19.3 0.0 0.0021 17.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Copper-fist PF00649.18 KND90506.1 - 5.8e-22 76.9 2.3 5.8e-22 76.9 2.3 3.6 1 1 3 4 4 4 2 Copper fist DNA binding domain Leu_leader PF08054.11 KND90506.1 - 0.071 12.7 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Leucine operon leader peptide FMO-like PF00743.19 KND90508.1 - 4.4e-12 45.2 3.6 2.5e-09 36.1 0.1 2.7 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KND90508.1 - 1e-11 44.6 0.0 4.3e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND90508.1 - 8.5e-08 32.3 0.0 1.5e-06 28.3 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND90508.1 - 1.1e-05 24.8 0.0 0.0013 18.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND90508.1 - 2.7e-05 23.5 0.1 0.19 10.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KND90508.1 - 0.00086 19.8 0.1 0.87 10.2 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND90508.1 - 0.0025 17.8 2.8 6 6.8 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KND90508.1 - 0.06 12.4 0.1 0.65 9.0 0.3 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KND90508.1 - 0.47 9.1 1.5 0.97 8.1 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein PHY PF00360.20 KND90509.1 - 4.8e-25 87.9 0.0 1e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KND90509.1 - 1.7e-15 57.5 0.1 3.4e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KND90509.1 - 1.1e-12 48.7 0.0 2.9e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KND90509.1 - 5.3e-12 45.6 1.9 1.2e-11 44.5 0.9 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KND90509.1 - 9.8e-12 45.0 0.1 1.2e-05 25.4 0.1 3.1 2 1 0 2 2 2 2 Response regulator receiver domain PAS_2 PF08446.11 KND90509.1 - 3.3e-09 37.4 0.0 1.2e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_2 PF13581.6 KND90509.1 - 0.031 14.2 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Transket_pyr PF02779.24 KND90511.1 - 2.4e-39 134.8 0.0 4.2e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KND90511.1 - 5.7e-31 107.0 0.0 1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KND90511.1 - 0.0022 18.3 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Glyco_hydro_18 PF00704.28 KND90512.1 - 1.4e-07 31.6 0.2 1.9e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KND90513.1 - 3.3e-20 73.1 0.0 5.1e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KND90513.1 - 2.4e-09 37.1 0.0 7.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KND90513.1 - 2e-07 31.4 7.2 2e-07 31.4 7.2 3.1 2 0 0 2 2 2 1 Chitin recognition protein Ribosomal_S5_C PF03719.15 KND90514.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Exo_endo_phos_2 PF14529.6 KND90515.1 - 8.3e-05 22.4 0.1 0.00014 21.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Cupin_8 PF13621.6 KND90516.1 - 3.8e-22 79.2 0.0 1.3e-21 77.5 0.0 1.9 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 KND90516.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 KND90516.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Cupin_6 PF12852.7 KND90516.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cupin JmjC PF02373.22 KND90516.1 - 0.12 12.8 0.0 0.62 10.5 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Ran-binding PF05508.11 KND90518.1 - 3.6e-113 377.7 0.0 5.1e-113 377.2 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein CLASP_N PF12348.8 KND90518.1 - 0.086 12.4 0.2 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 CLASP N terminal PEPCK_ATP PF01293.20 KND90520.1 - 2.2e-216 719.0 0.0 2.5e-216 718.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 KND90520.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KND90520.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KND90521.1 - 2.2e-42 144.8 0.0 3.6e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KND90521.1 - 1.9e-29 102.3 0.0 4.4e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KND90521.1 - 4.4e-09 36.6 0.4 2.4e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND90521.1 - 0.0055 16.8 0.0 0.027 14.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FCH PF00611.23 KND90522.1 - 3.4e-15 56.1 0.1 1.1e-14 54.5 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KND90522.1 - 5.4e-12 45.1 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND90522.1 - 3.4e-11 42.7 0.0 4e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KND90522.1 - 1.9e-10 40.5 0.1 4.2e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF4075 PF13294.6 KND90522.1 - 0.076 13.2 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF4407 PF14362.6 KND90522.1 - 6.6 6.0 11.8 12 5.1 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhzC-PhzF PF02567.16 KND90523.1 - 4.2e-38 131.4 0.1 6.7e-38 130.8 0.1 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein DUF4777 PF16007.5 KND90523.1 - 0.12 12.7 0.1 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Methyltransf_23 PF13489.6 KND90525.1 - 7.8e-17 61.6 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND90525.1 - 1.3e-05 25.9 0.0 0.013 16.1 0.0 3.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90525.1 - 0.00012 22.7 0.0 0.0012 19.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND90525.1 - 0.00028 21.5 0.0 0.0056 17.3 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90525.1 - 0.0032 17.3 0.0 0.71 9.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 KND90525.1 - 0.0037 16.6 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family UPF0029 PF01205.19 KND90526.1 - 8.7e-26 90.3 0.0 3.4e-25 88.4 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Pkinase PF00069.25 KND90527.1 - 5.6e-71 239.0 0.0 7.6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90527.1 - 7.1e-32 110.7 0.0 9.2e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND90527.1 - 0.0004 19.4 0.1 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 KND90527.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KND90527.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KND90527.1 - 0.0063 15.6 0.1 0.0093 15.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 KND90527.1 - 0.043 13.2 0.2 0.094 12.0 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 KND90528.1 - 2.1e-12 46.6 0.2 5.3e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90528.1 - 9.5e-05 22.4 7.6 0.00018 21.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHASE3 PF05227.13 KND90528.1 - 0.077 12.9 2.1 10 6.0 0.0 3.1 3 0 0 3 3 3 0 CHASE3 domain Vac_ImportDeg PF09783.9 KND90528.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar import and degradation protein TRAUB PF08164.12 KND90529.1 - 1.8e-30 105.3 0.2 5.9e-30 103.6 0.2 2.0 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KND90529.1 - 1.1e-26 94.2 0.5 1.1e-26 94.2 0.5 3.1 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor ParA PF10609.9 KND90530.1 - 3.5e-88 295.2 0.0 4.5e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KND90530.1 - 1.8e-10 41.0 0.0 6.5e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KND90530.1 - 2.3e-07 30.9 0.1 7.5e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KND90530.1 - 0.0002 20.7 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KND90530.1 - 0.00096 18.4 0.6 0.007 15.6 0.5 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 KND90530.1 - 0.0025 17.3 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KND90530.1 - 0.0025 17.6 0.3 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 KND90530.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 KND90530.1 - 0.016 14.8 0.4 0.043 13.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain Tudor_3 PF18115.1 KND90531.1 - 0.0016 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 KND90531.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) RRM_1 PF00076.22 KND90532.1 - 5e-07 29.4 0.1 9.9e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND90532.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Aminotran_3 PF00202.21 KND90534.1 - 5.2e-77 259.2 0.0 6.5e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 KND90535.1 - 3.3e-14 52.5 0.2 1e-13 51.0 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90535.1 - 3e-05 24.1 9.8 6.2e-05 23.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2046 PF09755.9 KND90536.1 - 0.0095 15.2 4.8 0.026 13.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Cnn_1N PF07989.11 KND90536.1 - 0.16 12.2 0.7 0.59 10.3 0.1 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 EBV-NA1 PF02905.14 KND90536.1 - 0.48 10.2 0.1 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain MFS_1 PF07690.16 KND90538.1 - 3.7e-38 131.4 35.2 3.7e-38 131.4 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND90538.1 - 5.8e-11 41.9 4.0 5.8e-11 41.9 4.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND90538.1 - 1.3e-05 23.9 2.0 1.3e-05 23.9 2.0 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KND90538.1 - 6.4e-05 21.5 0.6 0.00013 20.6 0.6 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector SLC3A2_N PF16028.5 KND90538.1 - 0.1 12.1 3.4 0.24 11.0 0.0 2.8 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus MFS_1_like PF12832.7 KND90538.1 - 0.1 11.4 8.7 0.017 14.0 4.0 2.1 1 1 1 2 2 2 0 MFS_1 like family Cellulase PF00150.18 KND90539.1 - 5.5e-12 45.7 0.5 5.5e-12 45.7 0.5 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) LAP1C PF05609.12 KND90539.1 - 0.041 13.0 5.0 0.06 12.4 5.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) EphA2_TM PF14575.6 KND90539.1 - 0.26 12.2 0.0 0.26 12.2 0.0 3.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Flavokinase PF01687.17 KND90540.1 - 2.1e-36 124.6 0.0 2.5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 KND90541.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 KND90541.1 - 0.016 15.3 9.6 0.016 15.3 9.6 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KND90542.1 - 1.7e-08 34.7 6.2 2.5e-08 34.1 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KND90542.1 - 3e-07 30.6 5.3 7.1e-07 29.4 5.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KND90542.1 - 1.5e-05 25.0 3.0 4.6e-05 23.4 3.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KND90542.1 - 0.0048 16.7 4.4 0.011 15.6 4.4 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND90542.1 - 0.0074 16.1 5.9 0.017 14.9 5.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND90542.1 - 0.019 14.7 3.6 0.019 14.7 1.6 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 KND90542.1 - 0.031 14.1 1.7 0.094 12.5 0.5 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF2397 PF09660.10 KND90542.1 - 0.052 12.5 0.1 0.071 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) zf-C3HC4 PF00097.25 KND90542.1 - 0.059 13.3 4.0 0.095 12.6 4.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND90542.1 - 0.2 11.7 3.4 0.18 11.8 1.5 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.6 KND90542.1 - 0.36 11.0 4.5 0.12 12.5 2.0 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger Tmpp129 PF10272.9 KND90542.1 - 0.74 9.1 3.1 1 8.6 3.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor NAD_binding_10 PF13460.6 KND90543.1 - 3.1e-12 46.8 0.4 5.2e-12 46.0 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND90543.1 - 2e-09 37.3 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 KND90543.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 HIM1 NmrA PF05368.13 KND90543.1 - 1.8e-05 24.4 0.1 3.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KND90543.1 - 0.0067 15.6 0.1 2 7.5 0.0 2.7 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 KND90543.1 - 0.014 14.5 0.0 0.05 12.6 0.0 1.9 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KND90543.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KND90544.1 - 1.3e-36 126.3 2.7 1.4e-31 109.8 0.7 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90544.1 - 1.1e-35 122.9 0.4 1.6e-35 122.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90544.1 - 2.4e-11 43.9 0.5 4.1e-11 43.1 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND90544.1 - 0.11 11.9 0.0 5 6.5 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3632 PF12311.8 KND90545.1 - 2.5e-37 129.0 7.2 3.2e-37 128.6 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans_2 PF11951.8 KND90546.1 - 3.7e-21 75.4 0.1 4.1e-18 65.4 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain PIN_4 PF13638.6 KND90546.1 - 0.084 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 PIN domain Methyltransf_33 PF10017.9 KND90549.1 - 2.6e-78 263.3 0.0 3e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent DNA_pol_phi PF04931.13 KND90550.1 - 4.7 5.2 8.3 5 5.1 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDF PF00375.18 KND90551.1 - 1e-06 28.0 2.8 1.2e-06 27.9 2.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DAO PF01266.24 KND90552.1 - 9.9e-30 104.3 0.0 1.2e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND90552.1 - 2.5e-08 33.5 0.1 0.00082 18.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND90552.1 - 1.5e-07 31.6 0.0 7.9e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND90552.1 - 7.1e-06 25.3 0.2 0.016 14.3 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 KND90552.1 - 0.00012 22.6 0.0 0.00038 21.0 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND90552.1 - 0.001 18.0 0.1 0.12 11.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.6 KND90552.1 - 0.001 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KND90552.1 - 0.0011 18.3 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KND90552.1 - 0.0029 16.9 0.0 0.0082 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KND90552.1 - 0.0035 17.6 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain HI0933_like PF03486.14 KND90552.1 - 0.0047 15.7 0.7 0.052 12.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KND90552.1 - 0.0052 16.8 0.1 7.4 6.5 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding ApbA PF02558.16 KND90552.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KND90552.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KND90552.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 KND90552.1 - 0.026 13.6 4.4 0.38 9.8 4.3 2.2 1 1 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 KND90552.1 - 0.028 14.7 0.0 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 KND90552.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 KND90552.1 - 0.092 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_1 PF00667.20 KND90553.1 - 1.1e-65 221.3 0.0 3.5e-65 219.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 KND90553.1 - 1.3e-09 38.6 0.0 5.2e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.18 KND90553.1 - 1.2e-08 35.2 0.0 2.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 KND90553.1 - 5.2e-07 29.9 0.1 1.7e-06 28.3 0.1 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KND90553.1 - 5.8e-05 23.0 0.1 0.00016 21.6 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Atx10homo_assoc PF09759.9 KND90554.1 - 1.4e-11 44.3 0.0 3.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Zip PF02535.22 KND90554.1 - 2.1 7.5 15.7 3.4 6.8 15.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PNP_UDP_1 PF01048.20 KND90555.1 - 1.2e-39 136.0 0.4 1.4e-39 135.8 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SNF2_N PF00176.23 KND90557.1 - 3.2e-67 226.7 4.3 7e-65 219.0 4.3 3.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND90557.1 - 6.9e-18 65.0 0.1 2.4e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90557.1 - 1.6e-06 28.3 2.1 5.1e-06 26.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND90557.1 - 1.6e-05 24.7 0.0 5e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 KND90557.1 - 0.0042 16.0 0.1 0.0083 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Cytochrom_c3_2 PF14537.6 KND90557.1 - 0.39 11.2 5.6 1.1 9.8 5.6 1.7 1 0 0 1 1 1 0 Cytochrome c3 VHS PF00790.19 KND90558.1 - 4.3e-37 127.1 0.1 1e-36 125.9 0.1 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KND90558.1 - 2.3e-16 59.1 0.5 5.3e-16 58.0 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KND90558.1 - 6.3e-15 54.8 1.0 1.2e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KND90558.1 - 2.1e-13 49.7 0.0 4.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KND90558.1 - 2.3e-10 40.6 1.6 2.3e-10 40.6 1.6 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KND90558.1 - 0.0062 16.4 2.7 0.015 15.1 2.7 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4375 PF14300.6 KND90558.1 - 1.9 8.8 3.7 1.7 9.0 1.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) Mito_carr PF00153.27 KND90559.1 - 5.5e-62 205.7 4.2 1.6e-25 88.9 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein RCC1 PF00415.18 KND90560.1 - 1.6e-20 73.4 1.1 1.6e-06 28.6 0.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KND90560.1 - 3.4e-14 53.0 0.0 1.1e-08 35.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KND90560.1 - 1.3e-10 41.6 0.2 3.5e-09 37.0 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 KND90560.1 - 3.2e-06 26.8 6.5 6.1e-05 22.7 0.8 3.6 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KND90560.1 - 1.2e-05 25.8 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND90560.1 - 3.5e-05 23.8 0.0 0.29 11.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat EF-hand_7 PF13499.6 KND90561.1 - 6e-16 58.7 3.5 9.5e-12 45.2 2.8 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KND90561.1 - 1.2e-14 52.6 6.7 2.1e-05 23.8 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KND90561.1 - 9.2e-13 47.8 10.2 5.6e-11 42.1 3.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KND90561.1 - 1.4e-11 43.3 4.4 0.0011 18.7 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 KND90561.1 - 3.5e-08 32.6 1.8 0.0003 20.2 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KND90561.1 - 0.00015 22.1 0.2 0.003 17.8 0.1 2.6 2 1 0 2 2 2 1 EF-hand domain Nup96 PF12110.8 KND90562.1 - 1.5e-89 300.0 0.7 2.8e-89 299.1 0.5 1.5 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KND90562.1 - 6.6e-48 162.6 0.0 1.1e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KND90562.1 - 1.1e-23 83.8 329.0 5.4e-09 36.8 35.2 11.6 4 2 8 12 12 12 7 Nucleoporin FG repeat region zf-C2H2 PF00096.26 KND90563.1 - 1.4e-20 72.5 29.1 1.7e-05 25.0 0.2 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND90563.1 - 7.9e-17 60.8 35.1 5.9e-06 26.5 2.2 5.7 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND90563.1 - 3.4e-09 36.7 29.9 0.015 16.1 0.2 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND90563.1 - 9.1e-09 35.4 1.2 0.039 14.2 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND90563.1 - 0.0027 18.1 10.7 2 8.9 0.0 4.3 4 0 0 4 4 4 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KND90563.1 - 0.045 14.4 3.6 11 6.7 0.1 3.4 1 1 2 3 3 3 0 FOXP coiled-coil domain C1_4 PF07975.12 KND90563.1 - 0.2 11.9 1.9 11 6.3 0.0 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_11 PF16622.5 KND90563.1 - 0.32 10.8 10.2 2.7 7.8 0.8 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type zf_UBZ PF18439.1 KND90563.1 - 0.5 10.0 4.0 6.8 6.4 0.0 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 KND90563.1 - 2.7 8.1 7.8 1.9 8.6 0.7 3.5 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2HC_2 PF13913.6 KND90563.1 - 4.8 7.2 6.3 4.2 7.4 0.2 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2256 PF10013.9 KND90563.1 - 6 7.1 8.2 29 4.9 0.0 3.5 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) DSBA PF01323.20 KND90564.1 - 3.6e-19 69.3 0.0 4.2e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KND90564.1 - 0.049 13.8 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin PEMT PF04191.13 KND90565.1 - 1.9e-33 115.0 2.5 3.2e-33 114.3 2.5 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase Nramp PF01566.18 KND90566.1 - 4.2e-85 285.8 17.4 4.2e-85 285.8 17.4 1.8 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein VHS PF00790.19 KND90566.1 - 1e-24 87.0 0.0 4.2e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KND90566.1 - 6.4e-07 29.6 0.4 1.3e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 GAT domain F-actin_cap_A PF01267.17 KND90567.1 - 2.6e-93 312.3 0.0 2e-92 309.4 0.0 1.9 1 1 0 1 1 1 1 F-actin capping protein alpha subunit DUF3993 PF13158.6 KND90567.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) TFA2_Winged_2 PF18121.1 KND90568.1 - 1.1e-20 73.0 0.0 2.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KND90568.1 - 1.4e-12 47.7 0.0 2.6e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain Cyt-b5 PF00173.28 KND90569.1 - 1.4e-23 82.8 0.2 1.9e-23 82.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 KND90569.1 - 0.027 14.5 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ETF_QO PF05187.13 KND90570.1 - 2.8e-34 117.4 2.8 6.1e-31 106.6 2.8 2.3 1 1 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 KND90570.1 - 2.8e-08 33.9 0.0 7.8e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND90570.1 - 1.9e-07 31.0 0.3 0.00026 20.7 0.3 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND90570.1 - 6.3e-05 22.2 0.6 0.0043 16.2 0.8 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KND90570.1 - 8.5e-05 21.9 0.0 0.00018 20.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND90570.1 - 0.00038 19.3 0.4 0.0006 18.6 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KND90570.1 - 0.00046 20.7 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KND90570.1 - 0.00056 19.3 0.1 0.0009 18.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KND90570.1 - 0.0006 19.1 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KND90570.1 - 0.002 18.1 0.1 0.011 15.7 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KND90570.1 - 0.003 16.5 0.1 0.26 10.1 0.1 2.2 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 KND90570.1 - 0.0034 16.7 0.2 0.0052 16.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KND90570.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KND90570.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 KND90570.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KND90570.1 - 0.067 12.2 0.3 0.096 11.7 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KND90570.1 - 0.074 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UvrD-helicase PF00580.21 KND90572.1 - 7.6e-63 212.9 1.6 1.7e-61 208.5 0.1 2.7 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KND90572.1 - 9.6e-62 209.4 0.0 6.3e-61 206.7 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KND90572.1 - 1.8e-32 112.7 0.1 1.1e-31 110.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 KND90572.1 - 1.1e-13 50.7 0.0 3.3e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KND90572.1 - 1.3e-08 34.8 0.4 0.00028 20.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KND90572.1 - 4.2e-05 23.4 0.2 0.42 10.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 KND90572.1 - 0.0011 18.6 0.1 0.031 13.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Helicase_RecD PF05127.14 KND90572.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.6 KND90572.1 - 0.22 11.3 1.7 0.82 9.4 0.1 2.6 3 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 KND90573.1 - 3e-81 267.3 5.9 4.9e-21 74.3 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KND90573.1 - 1.7e-28 98.6 1.5 7.6e-28 96.5 1.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 KND90573.1 - 1.3e-06 28.1 0.1 0.0035 17.2 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 KND90573.1 - 6e-06 26.3 0.4 0.83 9.8 0.0 5.3 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KND90573.1 - 7.7e-05 22.6 0.1 5.9 7.0 0.0 4.1 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KND90573.1 - 0.0022 18.4 7.7 0.037 14.5 1.0 3.5 3 0 0 3 3 3 1 Heat induced stress protein YflT CbiG_mid PF11761.8 KND90573.1 - 0.019 15.0 1.5 8.8 6.5 0.0 3.6 3 1 0 3 3 3 0 Cobalamin biosynthesis central region OB_RNB PF08206.11 KND90573.1 - 0.021 14.5 0.6 8.9 6.1 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain RNA_polI_A34 PF08208.11 KND90573.1 - 1.1 9.3 26.5 0.059 13.5 17.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 KND90573.1 - 1.1 8.0 8.6 2 7.1 8.6 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 KND90573.1 - 1.4 7.6 6.9 2.3 6.9 6.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 KND90573.1 - 1.5 6.8 17.0 2.4 6.2 17.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DHHA1 PF02272.19 KND90573.1 - 1.7 9.0 10.4 0.8 10.1 0.2 3.2 3 0 0 3 3 2 0 DHHA1 domain FAM176 PF14851.6 KND90573.1 - 9 6.0 9.6 37 4.0 9.6 2.1 1 0 0 1 1 1 0 FAM176 family Trp_oprn_chp PF09534.10 KND90574.1 - 0.088 12.6 0.4 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribosomal_S7 PF00177.21 KND90575.1 - 1.1e-24 86.8 0.0 1.8e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CcmD PF04995.14 KND90576.1 - 0.071 13.2 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2014 PF09427.10 KND90577.1 - 2.5e-109 364.7 8.4 3.6e-109 364.2 8.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 KND90577.1 - 1.9e-17 63.0 0.6 4.1e-17 61.9 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4110 PF13422.6 KND90577.1 - 0.23 11.6 1.1 28 4.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Ceramidase_alk PF04734.13 KND90579.1 - 2.4e-220 732.5 0.0 2.8e-220 732.3 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KND90579.1 - 1.4e-54 184.4 0.2 2.3e-54 183.7 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Usp PF00582.26 KND90580.1 - 5.5e-24 85.3 1.1 1.7e-21 77.2 1.1 2.8 1 1 0 1 1 1 1 Universal stress protein family NMO PF03060.15 KND90581.1 - 1.8e-45 155.8 2.0 1.4e-44 152.9 2.0 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND90581.1 - 2.1e-06 27.0 0.3 8.5e-05 21.7 0.2 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND90581.1 - 0.026 13.6 0.1 0.047 12.7 0.1 1.5 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KND90581.1 - 0.13 11.4 0.6 0.48 9.5 0.6 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 KND90581.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) F-box-like PF12937.7 KND90582.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.21 KND90584.1 - 2.9e-38 132.0 0.0 3.9e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND90584.1 - 0.07 11.6 0.1 0.33 9.4 0.0 1.8 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 KND90585.1 - 2.9e-56 189.9 1.2 5.5e-56 189.0 0.2 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 KND90585.1 - 1.5e-15 57.6 0.0 4.3e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain DUF2267 PF10025.9 KND90585.1 - 0.057 13.7 0.4 3.8 7.8 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_14 PF13428.6 KND90585.1 - 0.23 12.4 1.2 2.5 9.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 KND90586.1 - 4.9e-71 239.5 0.0 5.2e-50 170.4 0.0 2.2 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 KND90586.1 - 1.3e-10 41.9 0.0 3.2e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KND90586.1 - 3e-10 40.7 0.0 0.0014 19.3 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KND90586.1 - 1.3e-07 31.6 0.0 3.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KND90586.1 - 1.8e-07 31.7 0.1 0.03 14.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KND90586.1 - 8.8e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Raftlin PF15250.6 KND90586.1 - 0.00028 19.8 0.2 0.00028 19.8 0.2 2.0 2 0 0 2 2 2 1 Raftlin NNMT_PNMT_TEMT PF01234.17 KND90586.1 - 0.0024 17.1 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Med13_C PF06333.12 KND90587.1 - 1e-93 314.3 1.2 1e-93 314.3 1.2 3.2 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KND90587.1 - 3.1e-28 99.1 1.7 6.6e-28 98.0 0.2 2.2 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 KND90587.1 - 1.1e-12 48.4 5.7 6.8e-06 26.1 0.2 3.2 2 1 1 3 3 3 2 MID domain of medPIWI NUC153 PF08159.12 KND90588.1 - 8.7e-12 44.6 1.8 1.9e-11 43.6 1.8 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KND90588.1 - 1.3e-06 29.1 0.5 0.25 12.3 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90588.1 - 0.038 14.3 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LapA_dom PF06305.11 KND90589.1 - 0.15 11.9 0.5 0.22 11.3 0.5 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DASH_Duo1 PF08651.10 KND90590.1 - 0.013 15.2 3.7 0.013 15.2 3.7 5.4 6 2 1 7 7 7 0 DASH complex subunit Duo1 DUF5601 PF18151.1 KND90590.1 - 0.34 11.3 5.2 13 6.2 2.6 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) MFS_1 PF07690.16 KND90591.1 - 4.6e-23 81.7 39.4 4.6e-23 81.7 39.4 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyoxalase_6 PF18029.1 KND90591.1 - 0.02 15.7 0.0 0.12 13.2 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain OATP PF03137.20 KND90591.1 - 0.021 13.1 11.0 0.021 13.1 1.2 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyoxalase PF00903.25 KND90591.1 - 0.036 14.3 0.0 0.085 13.0 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Angiomotin_C PF12240.8 KND90592.1 - 0.0052 16.4 6.9 0.0052 16.4 6.9 2.2 2 0 0 2 2 2 1 Angiomotin C terminal Tropomyosin PF00261.20 KND90592.1 - 0.012 15.0 22.8 0.087 12.2 22.5 2.0 1 1 0 1 1 1 0 Tropomyosin DUF848 PF05852.11 KND90592.1 - 0.022 14.9 0.5 0.022 14.9 0.5 2.4 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.9 KND90592.1 - 0.08 13.0 17.2 2.2 8.3 11.0 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RmuC PF02646.16 KND90592.1 - 0.12 11.5 5.5 0.18 10.9 0.0 2.5 2 1 0 2 2 2 0 RmuC family TPR_MLP1_2 PF07926.12 KND90592.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KND90592.1 - 0.25 10.7 14.2 0.4 10.0 3.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 KND90592.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.8 2 1 1 3 3 3 0 TolA binding protein trimerisation Fez1 PF06818.15 KND90592.1 - 1.1 9.7 19.2 0.076 13.5 6.5 2.5 1 1 1 2 2 2 0 Fez1 KIP1 PF07765.12 KND90592.1 - 1.2 9.3 4.7 0.6 10.3 1.4 2.3 2 0 0 2 2 2 0 KIP1-like protein eIF3_N PF09440.10 KND90592.1 - 4.5 7.7 7.4 1.7 9.1 1.5 2.4 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain APH PF01636.23 KND90594.1 - 3.2e-14 53.4 0.2 8.3e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DDE_Tnp_IS66 PF03050.14 KND90594.1 - 0.038 13.5 0.6 0.06 12.8 0.6 1.3 1 0 0 1 1 1 0 Transposase IS66 family DUF2451 PF10474.9 KND90594.1 - 0.076 12.8 0.0 5.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Choline_kinase PF01633.20 KND90594.1 - 0.09 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chromo_shadow PF01393.19 KND90596.1 - 2.2e-20 72.5 0.5 2.2e-17 62.9 0.2 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KND90596.1 - 1.3e-09 37.8 0.0 1.3e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain NOA36 PF06524.12 KND90596.1 - 5.5 6.2 8.8 8.4 5.6 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein zf-Di19 PF05605.12 KND90597.1 - 0.019 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KND90597.1 - 0.045 14.6 0.1 0.096 13.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KND90597.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Kre28 PF17097.5 KND90597.1 - 0.09 11.7 2.3 0.14 11.1 2.3 1.2 1 0 0 1 1 1 0 Spindle pole body component Chibby PF14645.6 KND90597.1 - 0.098 13.1 1.7 0.24 11.8 1.7 1.6 1 0 0 1 1 1 0 Chibby family zf-C2H2 PF00096.26 KND90597.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KND90597.1 - 0.13 11.7 0.3 0.24 10.9 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain KCT2 PF17818.1 KND90597.1 - 0.76 9.9 2.5 2.1 8.5 2.5 1.7 1 0 0 1 1 1 0 Keratinocyte-associated gene product Neprosin PF03080.15 KND90598.1 - 1.6e-49 168.3 7.4 2e-49 167.9 7.4 1.1 1 0 0 1 1 1 1 Neprosin BSD PF03909.17 KND90600.1 - 1.2e-20 73.3 0.2 3.5e-20 71.8 0.2 1.9 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.14 KND90600.1 - 0.051 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Sigma-70 region 2 DUF5132 PF17195.4 KND90600.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) HisKA_3 PF07730.13 KND90600.1 - 0.066 13.7 1.2 5.7 7.5 0.0 2.9 2 1 0 2 2 2 0 Histidine kinase Phage_Gp111 PF07410.11 KND90600.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein GYD PF08734.11 KND90600.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 GYD domain WGG PF10273.9 KND90601.1 - 2.3e-33 114.7 1.7 2.4e-33 114.6 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Abhydrolase_3 PF07859.13 KND90602.1 - 1.6e-41 142.5 0.0 2.8e-31 109.0 0.0 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND90602.1 - 2.5e-12 46.4 0.0 9.5e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KND90602.1 - 0.0013 17.7 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 KND90602.1 - 0.0043 16.3 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 MRP-L27 PF09809.9 KND90603.1 - 5.3e-13 48.8 0.8 2.5e-12 46.6 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 Gryzun PF07919.12 KND90604.1 - 1.8e-233 776.6 0.0 2.2e-233 776.4 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 KND90604.1 - 2.5e-87 292.8 2.2 1.6e-80 270.4 2.8 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 KND90604.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF1622 PF07784.11 KND90604.1 - 0.13 12.1 0.0 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1622) MFS_1 PF07690.16 KND90605.1 - 2.3e-36 125.4 64.2 1.3e-35 123.0 64.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KND90605.1 - 6.1e-12 44.7 19.8 8e-12 44.4 19.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NeA_P2 PF12312.8 KND90606.1 - 0.79 9.1 7.7 8.6 5.7 3.1 2.2 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.11 KND90606.1 - 2.3 8.2 10.5 0.27 11.3 6.0 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KND90606.1 - 3.1 7.9 14.2 0.16 12.0 6.9 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KND90606.1 - 6.4 6.2 13.2 0.31 10.5 7.1 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Abhydrolase_6 PF12697.7 KND90607.1 - 3.8e-14 53.8 6.4 6.4e-14 53.1 6.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND90607.1 - 4.9e-10 39.1 0.0 7.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND90607.1 - 7.4e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 KND90607.1 - 0.00038 19.2 0.0 0.00064 18.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 KND90607.1 - 0.0042 16.6 0.0 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KND90607.1 - 0.0055 16.4 0.4 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Ser_hydrolase PF06821.13 KND90607.1 - 0.044 13.6 0.7 0.089 12.6 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase B12-binding PF02310.19 KND90607.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain Piwi PF02171.17 KND90608.1 - 1.3e-68 231.5 0.0 1.9e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KND90608.1 - 9.6e-11 42.4 0.0 1.6e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KND90608.1 - 8e-10 38.2 0.2 2e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KND90608.1 - 1.1e-08 35.2 0.0 4.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KND90608.1 - 2.1e-08 34.1 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KND90608.1 - 0.0013 18.9 0.2 0.011 15.9 0.0 2.5 3 0 0 3 3 3 1 Mid domain of argonaute Suc_Fer-like PF06999.12 KND90609.1 - 1.7e-69 233.6 0.0 2.4e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 KND90609.1 - 1.3e-09 37.8 0.0 7.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Peptidase_S10 PF00450.22 KND90610.1 - 1.1e-35 123.9 3.1 1.4e-35 123.5 3.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase UQ_con PF00179.26 KND90612.1 - 2.6e-20 72.5 0.1 3.6e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND90612.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Bac_surface_Ag PF01103.23 KND90613.1 - 1e-37 130.4 0.0 1.3e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Surface antigen ABC2_membrane PF01061.24 KND90614.1 - 9.1e-87 289.9 60.4 6.1e-45 153.2 25.8 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KND90614.1 - 5.6e-38 128.7 9.4 6e-33 112.6 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 KND90614.1 - 1.9e-35 122.4 0.0 2.9e-16 60.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KND90614.1 - 5e-19 68.7 0.0 3.7e-18 65.9 0.1 2.4 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 KND90614.1 - 1.2e-06 29.1 0.5 0.0012 19.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 KND90614.1 - 2.2e-05 24.1 0.0 0.0007 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND90614.1 - 2.3e-05 24.4 0.1 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KND90614.1 - 0.00018 21.5 0.0 0.8 9.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND90614.1 - 0.00023 20.9 0.6 0.036 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KND90614.1 - 0.00025 21.6 0.0 0.044 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND90614.1 - 0.00029 21.0 0.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KND90614.1 - 0.00046 20.5 0.1 0.15 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KND90614.1 - 0.0019 17.4 13.6 0.0019 17.4 13.6 3.3 2 2 1 3 3 3 1 ABC-2 family transporter protein IstB_IS21 PF01695.17 KND90614.1 - 0.0023 17.7 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 KND90614.1 - 0.0058 16.6 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 KND90614.1 - 0.0091 15.6 0.4 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KND90614.1 - 0.011 16.1 0.1 5.5 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KND90614.1 - 0.051 13.0 0.0 8.7 5.7 0.0 3.3 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 KND90614.1 - 0.055 13.9 0.0 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KND90614.1 - 0.057 13.1 0.0 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KND90614.1 - 0.073 13.6 0.3 0.24 11.9 0.2 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 KND90614.1 - 0.24 11.1 0.5 12 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KND90616.1 - 2.2e-06 27.9 0.0 1.4e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND90616.1 - 1e-05 25.8 0.0 5.5e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND90616.1 - 0.00028 20.8 0.0 0.00077 19.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 KND90616.1 - 0.03 14.3 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Nudix hydrolase domain FR47 PF08445.10 KND90616.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Vint PF14623.6 KND90618.1 - 1.5e-67 226.6 0.1 6.8e-67 224.4 0.0 2.1 3 0 0 3 3 3 1 Hint-domain Vwaint PF14624.6 KND90618.1 - 3.9e-29 100.6 0.0 7.2e-29 99.7 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KND90618.1 - 1.2e-14 54.9 0.0 3.2e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KND90618.1 - 1e-13 51.5 0.0 9.7e-13 48.3 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KND90618.1 - 5.4e-12 46.3 0.0 1.1e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Hint PF01079.20 KND90618.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Hint module Thiolase_N PF00108.23 KND90619.1 - 8.6e-67 225.2 1.2 1.1e-66 224.9 1.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND90619.1 - 9.3e-41 138.3 0.1 9.3e-41 138.3 0.1 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND90619.1 - 0.0004 20.1 3.7 0.00069 19.3 2.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KND90619.1 - 0.12 12.2 2.0 2.8 7.9 0.5 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Rad4 PF03835.15 KND90620.1 - 1.3e-29 102.8 0.0 3.1e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KND90620.1 - 2.3e-28 98.4 0.2 5.2e-28 97.3 0.2 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KND90620.1 - 4.4e-23 80.8 0.0 1.1e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KND90620.1 - 1.6e-19 70.6 1.1 1.6e-19 70.6 1.1 4.6 4 2 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KND90620.1 - 0.012 16.1 0.3 0.093 13.2 0.3 2.4 1 1 0 1 1 1 0 Transglutaminase-like superfamily ABC_tran PF00005.27 KND90621.1 - 8.1e-49 165.7 0.2 3.8e-27 95.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KND90621.1 - 2e-26 92.9 40.7 4.3e-18 65.5 15.4 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 KND90621.1 - 1.9e-23 83.7 0.7 2.5e-05 24.2 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND90621.1 - 7.7e-10 38.4 0.4 0.00029 20.5 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KND90621.1 - 7.5e-09 35.3 2.4 0.039 13.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 KND90621.1 - 0.00012 21.8 0.5 0.24 10.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KND90621.1 - 0.00021 21.2 0.5 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KND90621.1 - 0.00025 21.5 1.3 0.47 10.8 0.3 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KND90621.1 - 0.00081 20.0 15.8 0.012 16.1 0.3 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KND90621.1 - 0.0016 18.2 2.9 0.76 9.5 0.3 2.8 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KND90621.1 - 0.0039 16.5 0.5 1 8.6 0.2 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 KND90621.1 - 0.005 16.6 2.7 0.77 9.4 0.1 3.7 4 0 0 4 4 4 1 AAA ATPase domain MeaB PF03308.16 KND90621.1 - 0.011 14.7 1.0 0.12 11.3 0.1 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 KND90621.1 - 0.043 13.4 0.6 7.1 6.2 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KND90621.1 - 0.055 13.7 0.1 14 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.12 KND90621.1 - 0.075 12.8 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MukB PF04310.12 KND90621.1 - 0.084 12.7 0.5 16 5.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_18 PF13238.6 KND90621.1 - 0.12 12.9 0.1 32 5.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KND90621.1 - 0.19 11.3 1.8 15 5.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 KND90621.1 - 0.19 11.8 0.9 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 KND90621.1 - 1.1 9.4 6.8 3.7 7.8 0.3 3.2 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 KND90621.1 - 1.3 7.3 13.2 1.9 6.7 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein adh_short_C2 PF13561.6 KND90622.1 - 9.9e-33 113.6 2.4 4.8e-32 111.4 2.4 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90622.1 - 6.4e-32 110.6 2.7 1.2e-31 109.7 2.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90622.1 - 1.2e-10 41.6 0.2 3.5e-10 40.1 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KND90622.1 - 0.006 16.1 0.0 0.01 15.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KND90622.1 - 0.036 14.1 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KND90622.1 - 0.038 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KND90622.1 - 0.08 12.8 0.2 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Mito_carr PF00153.27 KND90623.1 - 8.1e-53 176.3 4.9 2.6e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BUD22 PF09073.10 KND90625.1 - 3.9e-100 336.2 25.6 4.5e-100 336.0 25.6 1.0 1 0 0 1 1 1 1 BUD22 Cyto_heme_lyase PF01265.17 KND90626.1 - 4.6e-123 410.5 0.0 5.2e-123 410.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DbpA PF03880.15 KND90627.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 KND90627.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TCO89 PF10452.9 KND90628.1 - 0.0037 16.3 17.2 0.069 12.1 0.0 3.2 3 0 0 3 3 3 2 TORC1 subunit TCO89 NicO PF03824.16 KND90628.1 - 6.4 6.0 6.7 10 5.4 6.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein ABC1 PF03109.16 KND90629.1 - 1e-22 80.5 0.0 7.9e-14 51.8 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KND90629.1 - 0.015 15.2 0.0 0.047 13.6 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family POTRA_TamA_1 PF17243.2 KND90629.1 - 0.05 13.7 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 RIO1 PF01163.22 KND90629.1 - 0.088 12.4 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KND90629.1 - 0.18 11.1 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain MOZ_SAS PF01853.18 KND90630.1 - 1e-75 253.3 0.0 1.4e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KND90630.1 - 9.6e-21 73.2 3.0 2.4e-20 71.9 3.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 KND90630.1 - 6.4e-07 29.4 4.1 2.3e-06 27.6 4.1 2.0 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KND90630.1 - 4.7e-05 23.2 1.9 4.7e-05 23.2 1.9 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KND90630.1 - 0.051 13.1 0.5 0.13 11.8 0.5 1.8 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KND90630.1 - 0.074 12.9 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MIZ PF02891.20 KND90630.1 - 0.1 12.4 2.4 0.21 11.4 2.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SET PF00856.28 KND90631.1 - 0.037 14.4 0.0 4.5 7.6 0.0 2.4 2 1 0 2 2 2 0 SET domain GSP_synth PF03738.14 KND90631.1 - 0.21 10.7 0.2 0.26 10.4 0.2 1.1 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp MFS_1 PF07690.16 KND90632.1 - 4.7e-35 121.2 28.3 3.7e-34 118.2 29.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KND90632.1 - 0.00094 18.1 5.2 0.00094 18.1 5.2 2.4 1 1 1 2 2 2 1 MFS_1 like family 7tm_1 PF00001.21 KND90633.1 - 0.00052 19.4 0.5 0.00052 19.4 0.5 2.0 2 1 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) SUR7 PF06687.12 KND90633.1 - 4.3 6.9 10.7 0.66 9.6 0.3 2.8 2 1 1 3 3 3 0 SUR7/PalI family Glyco_hydro_75 PF07335.11 KND90634.1 - 0.031 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATP_bind_3 PF01171.20 KND90636.1 - 2.6e-19 69.7 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 KND90636.1 - 8.4e-17 60.4 3.6 8.4e-17 60.4 3.6 3.5 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 KND90636.1 - 0.013 14.3 0.8 0.015 14.1 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase RecR PF02132.15 KND90636.1 - 0.098 12.2 0.5 0.098 12.2 0.5 3.5 5 0 0 5 5 5 0 RecR protein MWFE PF15879.5 KND90637.1 - 4.9e-24 84.2 0.2 7.9e-24 83.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit FAD_binding_3 PF01494.19 KND90638.1 - 4e-17 62.5 2.1 5.4e-06 25.9 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KND90638.1 - 1.8e-05 24.9 0.1 4.3e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND90638.1 - 3.2e-05 23.7 0.7 7.8e-05 22.4 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KND90638.1 - 0.058 12.4 0.3 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KND90638.1 - 0.097 11.9 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_L7Ae PF01248.26 KND90639.1 - 1.9e-21 75.6 0.9 3.1e-21 74.9 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 KND90639.1 - 0.094 11.7 0.2 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) NTF2 PF02136.20 KND90640.1 - 2.2e-29 102.5 0.3 2.7e-29 102.2 0.3 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 KND90640.1 - 0.11 13.0 0.0 0.17 12.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) ATG13 PF10033.9 KND90641.1 - 8.7e-75 251.5 0.0 1.3e-74 251.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 NTP_transf_8 PF12281.8 KND90641.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase ENTH PF01417.20 KND90642.1 - 3.6e-46 156.3 0.0 5.8e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 KND90642.1 - 0.00023 21.5 36.0 0.00023 21.5 36.0 5.8 3 1 3 6 6 6 1 Domain of unknown function (DUF1720) UIM PF02809.20 KND90642.1 - 0.00037 20.2 6.6 0.0039 17.0 1.0 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF4264 PF14084.6 KND90642.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) VHS PF00790.19 KND90642.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 VHS domain CK_II_beta PF01214.18 KND90644.1 - 3.7e-71 238.7 0.1 1.1e-70 237.2 0.1 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KND90644.1 - 0.12 10.8 1.2 0.16 10.5 1.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 KND90644.1 - 0.15 11.8 1.0 0.21 11.4 1.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.11 KND90644.1 - 0.2 9.7 1.2 0.25 9.4 1.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KND90644.1 - 0.22 9.8 3.8 0.28 9.4 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M24 PF00557.24 KND90647.1 - 2.5e-26 92.7 0.1 1.1e-14 54.6 0.0 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 IPU_b_solenoid PF18783.1 KND90649.1 - 0.11 12.5 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat HgmA PF04209.13 KND90650.1 - 1.1e-189 630.6 0.0 1.3e-189 630.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase PH PF00169.29 KND90651.1 - 0.00021 21.8 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 KND90651.1 - 0.0012 18.7 1.3 0.0016 18.4 0.3 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain eRF1_3 PF03465.15 KND90651.1 - 0.1 13.1 0.0 0.41 11.2 0.0 2.0 1 1 1 2 2 2 0 eRF1 domain 3 Arrestin_C PF02752.22 KND90652.1 - 8.7e-17 61.8 0.0 3.5e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KND90652.1 - 1.4e-15 57.6 0.0 2.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KND90652.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like PAS_9 PF13426.7 KND90653.1 - 4.6e-12 46.1 0.0 7.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 KND90653.1 - 0.0027 17.7 0.0 0.006 16.6 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 KND90653.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 KND90653.1 - 0.04 14.2 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fapy_DNA_glyco PF01149.24 KND90654.1 - 3.2e-36 124.5 0.0 5.2e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 KND90654.1 - 2.5e-20 72.3 0.0 4.8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 KND90654.1 - 0.014 14.2 0.0 0.025 13.3 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Peptidase_S10 PF00450.22 KND90655.1 - 7.1e-74 249.7 1.2 1.1e-73 249.1 1.2 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase zf-Nse PF11789.8 KND90656.1 - 6.9e-23 80.2 0.3 1.2e-22 79.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 KND90656.1 - 0.00016 21.3 0.7 0.00028 20.6 0.7 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 KND90656.1 - 0.00095 19.1 0.6 0.0018 18.3 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KND90656.1 - 0.0028 17.5 0.5 0.005 16.7 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND90656.1 - 0.058 13.4 0.1 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KND90656.1 - 0.07 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND90656.1 - 0.15 12.4 0.7 0.27 11.6 0.7 1.4 1 0 0 1 1 1 0 Ring finger domain CorA PF01544.18 KND90656.1 - 6.8 5.9 9.4 0.15 11.4 2.0 1.9 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DHBP_synthase PF00926.19 KND90657.1 - 1.2e-79 266.3 0.0 1.4e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 KND90658.1 - 1.1e-20 74.1 0.0 1.8e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND90658.1 - 5.9e-18 65.3 0.0 9.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90658.1 - 1.2e-14 54.4 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND90658.1 - 5.3e-14 52.7 0.0 9.4e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90658.1 - 4.3e-13 49.8 0.0 7.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND90658.1 - 2.2e-05 23.9 0.0 3.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KND90658.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 KND90658.1 - 0.0042 16.7 0.0 0.0057 16.3 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KND90658.1 - 0.0042 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KND90658.1 - 0.02 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 KND90658.1 - 0.039 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) WD40 PF00400.32 KND90659.1 - 4.6e-12 46.3 12.2 0.0002 22.1 0.4 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90659.1 - 2.8e-08 33.9 0.0 0.0018 18.5 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND90659.1 - 0.003 17.5 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KND90659.1 - 0.13 10.8 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain EF_assoc_2 PF08356.12 KND90660.1 - 1.9e-34 117.5 0.0 4.5e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KND90660.1 - 3.7e-28 96.9 0.0 8.5e-28 95.8 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KND90660.1 - 1.8e-22 79.7 0.0 2.9e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KND90660.1 - 2.6e-13 50.2 0.0 1.8e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KND90660.1 - 1.4e-08 34.8 0.0 0.0015 18.6 0.0 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KND90660.1 - 4.3e-08 32.2 8.9 0.0013 18.2 0.9 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 KND90660.1 - 1.4e-07 31.8 2.1 0.00044 20.6 0.9 2.7 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 KND90660.1 - 1.3e-06 28.6 0.1 0.0037 17.4 0.1 2.9 2 1 1 3 3 3 2 Dynamin family EF-hand_6 PF13405.6 KND90660.1 - 2e-06 27.3 4.8 0.019 14.9 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain AAA_22 PF13401.6 KND90660.1 - 9.2e-05 22.7 0.0 0.0087 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND90660.1 - 0.00015 21.4 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KND90660.1 - 0.00029 21.1 0.0 0.76 10.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KND90660.1 - 0.0003 21.2 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 KND90660.1 - 0.003 17.1 0.0 8 5.9 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KND90660.1 - 0.0043 17.0 0.0 4.3 7.2 0.0 3.3 2 1 0 3 3 3 1 RsgA GTPase Ploopntkinase3 PF18751.1 KND90660.1 - 0.0059 16.5 0.0 0.11 12.4 0.0 2.6 3 0 0 3 3 3 1 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KND90660.1 - 0.011 16.2 0.0 0.68 10.4 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 KND90660.1 - 0.015 15.5 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 KND90660.1 - 0.016 14.7 11.2 0.072 12.6 2.6 3.1 3 0 0 3 3 3 0 EF hand AAA_24 PF13479.6 KND90660.1 - 0.025 14.3 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 KND90660.1 - 0.034 14.0 1.5 0.33 10.9 0.2 2.4 2 0 0 2 2 2 0 EF hand RNA_helicase PF00910.22 KND90660.1 - 0.07 13.5 0.0 23 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF3052 PF11253.8 KND90660.1 - 0.091 12.7 0.0 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) DUF815 PF05673.13 KND90660.1 - 0.092 11.9 0.0 5.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MCM PF00493.23 KND90660.1 - 0.13 11.3 0.0 11 5.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain SPARC_Ca_bdg PF10591.9 KND90660.1 - 0.18 12.1 0.9 14 6.0 0.1 3.1 3 1 1 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 KND90660.1 - 1.3 8.9 6.7 12 5.8 0.4 2.8 2 0 0 2 2 2 0 EF-hand domain pair Cyclin_N PF00134.23 KND90661.1 - 1.2e-14 54.2 0.0 1.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KND90661.1 - 3.2e-07 30.9 1.4 5.6e-07 30.1 0.3 2.0 2 1 0 2 2 2 1 Cyclin E1-E2_ATPase PF00122.20 KND90662.1 - 3.4e-48 163.6 0.5 8.6e-48 162.2 0.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KND90662.1 - 2.3e-32 113.0 0.1 6.4e-32 111.5 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KND90662.1 - 2e-19 69.8 0.2 8.7e-12 45.3 0.1 3.8 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KND90662.1 - 1.5e-07 31.5 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND90662.1 - 1.6e-05 25.4 0.0 4.9e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 KND90662.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat PAP1 PF08601.10 KND90663.1 - 3.3e-74 250.9 48.1 4.8e-53 181.2 6.4 3.7 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 KND90663.1 - 2.7e-08 33.8 12.0 6.2e-08 32.6 12.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 KND90663.1 - 0.0007 20.2 2.6 0.0017 18.9 2.6 1.7 1 0 0 1 1 1 1 SlyX CCDC158 PF15921.5 KND90663.1 - 0.001 17.0 1.1 0.0015 16.5 1.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 bZIP_2 PF07716.15 KND90663.1 - 0.0072 16.4 13.2 0.024 14.7 13.2 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Tropomyosin PF00261.20 KND90663.1 - 0.0076 15.7 8.5 0.014 14.8 8.5 1.3 1 0 0 1 1 1 1 Tropomyosin SHE3 PF17078.5 KND90663.1 - 0.0082 15.9 8.2 0.0082 15.9 8.2 2.0 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 DUF812 PF05667.11 KND90663.1 - 0.0087 15.0 5.9 0.016 14.1 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 KND90663.1 - 0.0098 16.4 11.2 0.023 15.2 11.2 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 KND90663.1 - 0.066 13.3 3.1 0.16 12.1 3.1 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation FlaC_arch PF05377.11 KND90663.1 - 0.097 13.1 0.9 0.21 12.0 0.9 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Nop53 PF07767.11 KND90663.1 - 0.12 11.8 16.0 0.22 10.9 16.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF16 PF01519.16 KND90663.1 - 0.29 11.6 3.6 0.77 10.3 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DOG1 PF14144.6 KND90663.1 - 0.33 11.2 1.0 0.89 9.8 1.0 1.7 1 0 0 1 1 1 0 Seed dormancy control DUF641 PF04859.12 KND90663.1 - 0.63 10.4 5.7 14 6.0 4.4 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.17 KND90663.1 - 0.7 9.8 3.9 1.3 9.0 3.9 1.4 1 0 0 1 1 1 0 Prefoldin subunit APG6_N PF17675.1 KND90663.1 - 1.1 9.8 10.2 0.14 12.7 5.9 1.6 2 0 0 2 2 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 KND90663.1 - 1.2 7.0 2.7 1.9 6.3 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 KND90663.1 - 1.7 9.0 7.6 0.63 10.4 1.1 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain SpoIIIAH PF12685.7 KND90663.1 - 1.9 8.3 7.6 5.1 6.9 7.6 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4446 PF14584.6 KND90663.1 - 4.1 7.4 5.2 8.9 6.3 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) CDC45 PF02724.14 KND90663.1 - 5.6 5.1 13.6 8.4 4.6 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KND90664.1 - 4.1e-44 150.9 0.0 6e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND90664.1 - 3.7e-21 75.6 0.0 5.2e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND90664.1 - 0.0013 18.7 1.8 0.0034 17.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND90664.1 - 0.0015 17.9 0.1 0.0025 17.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND90664.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Mito_fiss_reg PF05308.11 KND90664.1 - 0.3 11.1 2.4 0.63 10.1 2.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 KND90664.1 - 6.7 6.8 13.6 13 5.8 13.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Surp PF01805.20 KND90665.1 - 7.4e-09 35.5 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Surp module Fungal_trans PF04082.18 KND90666.1 - 9e-09 34.7 0.8 9e-09 34.7 0.8 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND90666.1 - 0.00018 21.8 11.2 0.0086 16.5 0.2 4.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND90666.1 - 0.00055 20.2 1.8 0.00055 20.2 1.8 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND90666.1 - 0.0014 19.3 9.1 1.2 10.1 0.2 4.3 3 0 0 3 3 3 2 C2H2-type zinc finger Methyltransf_16 PF10294.9 KND90667.1 - 1.1e-08 35.1 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase PhyH PF05721.13 KND90667.1 - 1.4e-08 35.3 0.0 6.1e-08 33.2 0.0 2.0 2 2 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Copper-fist PF00649.18 KND90668.1 - 5.7e-19 67.3 0.7 1.6e-18 65.9 0.7 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Glyco_hydro_125 PF06824.11 KND90669.1 - 3.5e-173 576.3 0.1 6.9e-172 572.0 0.1 2.0 1 1 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) HECT PF00632.25 KND90670.1 - 4.9e-77 259.4 0.0 8.9e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KND90670.1 - 1.2e-05 24.6 0.8 4.1e-05 23.0 0.8 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Acetyltransf_2 PF00797.17 KND90670.1 - 0.0097 15.7 0.3 0.022 14.6 0.3 1.5 1 0 0 1 1 1 1 N-acetyltransferase RXT2_N PF08595.11 KND90671.1 - 1.9e-45 154.7 0.2 6.9e-45 152.9 0.0 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal Glyco_hydro_3 PF00933.21 KND90672.1 - 1.7e-61 208.4 0.0 2.3e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 KND90672.1 - 0.004 17.4 0.0 0.075 13.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family PNP_UDP_1 PF01048.20 KND90672.1 - 0.081 12.2 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Phosphorylase superfamily Hexokinase_2 PF03727.16 KND90673.1 - 5.3e-56 189.7 0.0 7.7e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KND90673.1 - 9.4e-40 136.6 0.0 1.4e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase LRIF1 PF15741.5 KND90673.1 - 0.12 10.9 0.0 0.63 8.5 0.0 1.8 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 ESCRT-II PF05871.12 KND90674.1 - 3e-55 186.3 0.0 3.7e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 KND90675.1 - 1.4e-32 111.5 0.0 5.3e-30 103.3 0.0 3.6 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KND90675.1 - 5.2e-26 90.4 0.0 2.4e-19 69.0 0.1 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KND90675.1 - 3.1e-24 85.1 0.0 1.9e-08 34.6 0.0 6.4 6 1 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND90675.1 - 8.9e-19 67.7 0.0 0.00058 20.2 0.0 6.2 6 0 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KND90675.1 - 6.9e-08 32.7 0.4 0.092 13.1 0.0 3.7 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KND90675.1 - 4.9e-06 26.5 0.0 0.04 14.0 0.0 4.3 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Pyr_redox_2 PF07992.14 KND90676.1 - 1.5e-42 145.9 0.5 2.3e-42 145.2 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KND90676.1 - 8.7e-20 70.8 0.0 1.6e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KND90676.1 - 4.1e-17 62.5 5.9 1.5e-16 60.7 1.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 KND90676.1 - 1.5e-12 47.7 8.4 3.7e-09 36.8 7.6 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KND90676.1 - 2.9e-12 46.4 0.1 1.3e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 KND90676.1 - 3.9e-12 46.0 0.0 7.2e-11 42.0 0.0 2.7 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KND90676.1 - 3.4e-11 42.8 0.0 7.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KND90676.1 - 1.4e-05 24.9 0.7 0.12 12.3 0.1 3.8 5 0 0 5 5 5 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 KND90676.1 - 0.0034 17.4 0.9 13 5.8 0.0 3.6 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KND90676.1 - 0.006 15.9 0.5 0.39 9.9 0.0 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase S_layer_N PF05123.12 KND90676.1 - 0.02 14.8 0.1 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 S-layer like family, N-terminal region NAD_binding_7 PF13241.6 KND90676.1 - 0.048 14.1 0.3 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KND90676.1 - 0.091 11.8 1.0 5.7 5.9 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 KND90676.1 - 0.58 9.4 1.9 3.3 6.9 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amidohydro_1 PF01979.20 KND90677.1 - 3.7e-12 46.2 0.0 1.5e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND90677.1 - 1.6e-10 41.1 0.3 4.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family NDT80_PhoG PF05224.12 KND90678.1 - 4.2e-36 124.9 0.0 6.7e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family SRR1 PF07985.12 KND90679.1 - 1.4e-07 31.4 0.0 2.5e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 Glucosamine_iso PF01182.20 KND90680.1 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Seipin PF06775.14 KND90681.1 - 5.4e-58 196.4 0.6 6.6e-58 196.1 0.6 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.15 KND90682.1 - 1.7e-134 448.4 0.0 3.2e-134 447.5 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KND90682.1 - 1.9e-89 298.9 0.4 3.8e-89 297.9 0.4 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KND90682.1 - 1.3e-46 158.2 1.4 1.3e-46 158.2 1.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KND90682.1 - 7.8e-41 139.3 0.0 2.4e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KND90682.1 - 5e-40 137.0 0.0 2.6e-39 134.7 0.0 2.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Na_Ca_ex PF01699.24 KND90683.1 - 4.1e-47 159.9 38.5 2e-25 89.5 17.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro81C PF17652.1 KND90684.1 - 1.7e-156 520.8 7.7 2.2e-156 520.5 7.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KND90684.1 - 2.4e-115 385.1 0.2 3.5e-115 384.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Stn1 PF10451.9 KND90685.1 - 1.2e-15 57.2 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KND90685.1 - 1.6e-05 24.8 0.2 2.9e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KND90685.1 - 3.5e-05 23.6 0.0 7.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 RecQ-mediated genome instability protein 2 Cid2 PF09774.9 KND90685.1 - 0.05 14.0 0.7 0.073 13.5 0.7 1.2 1 0 0 1 1 1 0 Caffeine-induced death protein 2 PaaB PF06243.11 KND90685.1 - 0.078 13.2 0.1 0.14 12.4 0.1 1.3 1 0 0 1 1 1 0 Phenylacetic acid degradation B DnaJ PF00226.31 KND90686.1 - 4.6e-23 81.1 1.3 1.2e-22 79.7 1.3 1.8 1 0 0 1 1 1 1 DnaJ domain Nif11 PF07862.11 KND90686.1 - 0.043 14.1 7.9 0.33 11.3 0.0 4.5 4 1 0 4 4 4 0 Nif11 domain Inv-AAD PF18785.1 KND90687.1 - 2.4e-55 185.9 0.1 2.9e-55 185.6 0.1 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KND90687.1 - 5.4e-12 45.5 0.0 7.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KND90687.1 - 0.0085 16.0 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Glyco_hydro_115 PF15979.5 KND90688.1 - 1.6e-128 428.9 0.4 2.1e-128 428.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KND90689.1 - 1.5e-40 138.8 0.0 2e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain CxC7 PF18866.1 KND90690.1 - 0.38 10.9 5.8 6.7 6.9 0.2 2.6 2 1 0 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases COX15-CtaA PF02628.15 KND90691.1 - 1.2e-112 376.2 7.1 1.4e-112 375.9 7.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Utp14 PF04615.13 KND90692.1 - 1.6e-187 625.6 72.2 1.6e-187 625.6 72.2 2.7 1 1 1 2 2 2 1 Utp14 protein DUF4604 PF15377.6 KND90693.1 - 2e-33 116.2 19.8 2.3e-33 116.1 19.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Presenilin PF01080.17 KND90693.1 - 5.7 5.6 5.4 7.9 5.1 5.4 1.3 1 0 0 1 1 1 0 Presenilin DUF2427 PF10348.9 KND90694.1 - 2.5e-06 27.2 2.8 2.5e-06 27.2 2.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KND90694.1 - 0.002 18.3 8.3 0.002 18.3 8.3 1.8 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 Abhydrolase_9_N PF15420.6 KND90694.1 - 0.25 11.3 5.1 0.33 10.9 1.1 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus E1-E2_ATPase PF00122.20 KND90695.1 - 1.6e-39 135.3 1.0 3.9e-38 130.8 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND90695.1 - 2.4e-34 118.6 5.6 2.4e-34 118.6 5.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KND90695.1 - 2e-23 83.8 0.3 1e-10 42.3 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND90695.1 - 8.8e-15 54.6 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KND90695.1 - 1.7e-12 46.8 0.0 1.5e-11 43.8 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND90695.1 - 0.016 14.9 0.2 0.03 14.0 0.2 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 KND90695.1 - 0.03 14.8 1.7 0.066 13.7 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) HAD PF12710.7 KND90695.1 - 0.078 13.4 0.0 1.5 9.2 0.0 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GFO_IDH_MocA PF01408.22 KND90696.1 - 6.1e-25 88.4 0.5 1.1e-24 87.6 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KND90696.1 - 1.2e-06 28.6 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 KND90696.1 - 0.028 14.6 0.1 0.1 12.7 0.1 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Fungal_trans_2 PF11951.8 KND90697.1 - 2.7e-10 39.6 2.4 2.7e-10 39.6 2.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KND90699.1 - 2.2e-12 46.6 1.2 2.5e-12 46.4 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90699.1 - 0.0092 14.9 7.8 0.016 14.1 6.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Caroten_synth PF04240.12 KND90699.1 - 0.019 14.9 0.4 0.025 14.5 0.4 1.1 1 0 0 1 1 1 0 Carotenoid biosynthesis protein SLAC1 PF03595.17 KND90700.1 - 1e-48 166.3 26.1 1.1e-48 166.1 26.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Mem_trans PF03547.18 KND90700.1 - 4.1 5.7 10.1 0.6 8.4 5.9 1.7 1 1 1 2 2 2 0 Membrane transport protein APH PF01636.23 KND90701.1 - 2.4e-12 47.3 0.0 2.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND90701.1 - 0.0004 20.1 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND90701.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 KND90701.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Cupin_1 PF00190.22 KND90702.1 - 3.2e-39 134.0 0.0 2e-19 69.7 0.0 2.4 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.11 KND90702.1 - 1.6e-23 82.1 2.7 4.2e-11 42.4 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 KND90702.1 - 6.8e-06 25.7 0.0 0.056 13.1 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KND90702.1 - 9.1e-05 22.4 0.3 0.18 11.7 0.2 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Amidinotransf PF02274.17 KND90703.1 - 5.2e-08 32.4 0.0 0.0058 15.8 0.0 3.6 3 1 0 3 3 3 3 Amidinotransferase DUF1996 PF09362.10 KND90704.1 - 8.4e-68 228.9 0.2 9.9e-68 228.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_2 PF00891.18 KND90708.1 - 5.2e-13 48.8 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Aldo_ket_red PF00248.21 KND90709.1 - 1.1e-37 129.9 0.0 2.5e-35 122.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 KND90710.1 - 1.9e-77 261.1 15.0 7.3e-77 259.1 15.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter PRKCSH-like PF12999.7 KND90710.1 - 2.6e-42 144.6 2.7 1.5e-24 86.7 0.4 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KND90710.1 - 8.1e-25 87.3 0.0 1.8e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1 PF07690.16 KND90710.1 - 5.5e-19 68.3 43.0 5.5e-19 68.3 43.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PRKCSH PF07915.13 KND90710.1 - 3.7e-05 24.7 0.1 8.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein MFS_1_like PF12832.7 KND90710.1 - 0.071 12.0 3.0 0.11 11.3 3.0 1.3 1 0 0 1 1 1 0 MFS_1 like family Mod_r PF07200.13 KND90710.1 - 0.19 11.8 11.5 0.019 15.1 2.4 2.8 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CCCAP PF15964.5 KND90710.1 - 0.65 8.2 12.5 1.1 7.4 12.5 1.3 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family DUF2721 PF11026.8 KND90710.1 - 8.4 6.3 9.2 5 7.0 2.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) FAT PF02259.23 KND90711.1 - 1.1e-132 442.5 8.1 1.1e-132 442.5 8.1 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KND90711.1 - 1.4e-76 255.9 7.3 4e-72 241.4 0.7 5.3 5 1 0 6 6 5 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KND90711.1 - 1e-73 248.3 0.0 1.9e-73 247.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KND90711.1 - 3e-45 152.6 0.3 3e-45 152.6 0.3 3.8 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 KND90711.1 - 3.9e-13 49.0 0.1 1.3e-12 47.3 0.1 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 KND90711.1 - 2.5e-12 45.9 7.6 0.0026 17.9 0.0 9.2 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 KND90711.1 - 3.4e-09 37.0 8.5 0.041 14.3 0.0 8.1 8 0 0 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 KND90711.1 - 1.1e-08 35.3 10.6 0.0032 17.9 0.0 9.6 8 2 2 10 10 9 2 HEAT-like repeat Cnd1 PF12717.7 KND90711.1 - 5.7e-07 29.7 1.6 0.026 14.5 0.0 6.3 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KND90711.1 - 5.2e-05 22.9 7.3 10 5.6 0.0 6.7 6 1 1 7 7 7 1 CLASP N terminal Adaptin_N PF01602.20 KND90711.1 - 9.1e-05 21.2 8.5 0.0091 14.6 4.7 4.6 3 1 0 4 4 4 1 Adaptin N terminal region Baculo_PEP_C PF04513.12 KND90711.1 - 0.046 13.8 2.3 0.11 12.5 0.4 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ANAPC3 PF12895.7 KND90711.1 - 0.27 11.5 6.6 4.9 7.4 0.1 4.3 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KND90711.1 - 4.8 7.5 7.6 1.2e+02 3.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NMT1 PF09084.11 KND90712.1 - 2e-77 260.0 0.0 2.5e-77 259.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 KND90712.1 - 5.7e-07 29.5 0.0 0.17 11.6 0.0 3.6 3 1 0 3 3 3 3 NMT1-like family Fungal_trans PF04082.18 KND90714.1 - 4.5e-14 52.1 0.0 2.2e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90714.1 - 1.3e-05 25.2 9.6 2.3e-05 24.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND90715.1 - 3e-27 95.3 0.1 1.6e-26 92.9 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.24 KND90716.1 - 1.3e-31 109.8 4.6 1.3e-31 109.8 4.6 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND90716.1 - 3.3e-20 72.8 1.6 5.8e-20 72.0 0.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND90716.1 - 3.9e-20 71.8 0.0 7.3e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND90716.1 - 3.3e-13 50.1 10.0 7.1e-13 49.0 5.6 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DHDPS PF00701.22 KND90717.1 - 2.3e-37 128.3 0.0 2.8e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 KND90718.1 - 1.5e-31 109.6 27.9 1.5e-31 109.6 27.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Herpes_gE PF02480.16 KND90718.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Abhydrolase_3 PF07859.13 KND90719.1 - 1.6e-63 214.4 0.1 2.2e-63 213.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND90719.1 - 2e-06 27.4 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KND90719.1 - 1.4e-05 24.2 0.1 0.00016 20.7 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family D-ser_dehydrat PF14031.6 KND90720.1 - 2.3e-22 79.5 0.0 6.2e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KND90720.1 - 4.8e-14 52.5 2.3 6.8e-14 52.0 2.3 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF2807 PF10988.8 KND90720.1 - 0.078 12.8 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Glyco_hydro_1 PF00232.18 KND90722.1 - 1.9e-148 494.6 0.0 2.2e-148 494.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 KND90722.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Sugar_tr PF00083.24 KND90723.1 - 1.4e-74 251.6 23.7 1.7e-74 251.3 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90723.1 - 6.8e-25 87.7 54.0 4.3e-20 71.9 15.3 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily DEAD PF00270.29 KND90724.1 - 1.7e-39 135.4 0.1 2.8e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND90724.1 - 2e-30 105.4 0.6 7.9e-29 100.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90724.1 - 1.5e-05 25.0 0.2 4.8e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KND90724.1 - 0.00024 19.6 0.8 0.0003 19.3 0.8 1.2 1 0 0 1 1 1 1 CDC45-like protein FAM110_C PF14160.6 KND90724.1 - 0.04 15.0 0.1 3.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus Glyco_hydro_16 PF00722.21 KND90726.1 - 7.5e-45 152.6 1.8 1.4e-44 151.7 1.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HMA PF00403.26 KND90727.1 - 2.7e-10 40.5 0.0 4.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KND90727.1 - 5.6e-10 39.5 0.1 9.2e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_1 PF00515.28 KND90728.1 - 5.8e-16 57.6 4.7 1.6e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND90728.1 - 3.2e-15 54.9 3.6 1.9e-06 27.5 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND90728.1 - 3.4e-10 39.3 3.5 6.8e-06 25.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KND90728.1 - 1.9e-08 34.4 0.3 0.084 13.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND90728.1 - 3.3e-08 33.0 0.1 3.7e-06 26.6 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND90728.1 - 4e-08 33.4 0.5 2.2e-07 31.1 0.1 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KND90728.1 - 6.1e-07 29.0 1.7 1.1e-05 24.9 0.1 3.4 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 KND90728.1 - 2.5e-05 24.3 0.2 0.15 12.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND90728.1 - 0.00018 22.1 0.3 0.0072 16.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND90728.1 - 0.00024 21.3 0.1 0.26 11.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND90728.1 - 0.0057 17.4 0.3 0.2 12.6 0.0 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat PB1 PF00564.24 KND90728.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_10 PF13374.6 KND90728.1 - 0.032 14.1 2.4 0.17 11.8 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND90728.1 - 0.095 13.4 0.2 45 5.1 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 KND90729.1 - 4.1e-86 288.7 0.0 5.9e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 KND90730.1 - 3.9e-36 124.4 0.1 6e-36 123.8 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND90730.1 - 1.1e-23 83.1 5.9 1.8e-23 82.4 5.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND90730.1 - 8.7e-14 51.6 18.7 8.7e-14 51.6 18.7 1.7 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KND90730.1 - 0.005 16.8 11.7 0.19 11.7 0.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Malate_DH PF12434.8 KND90730.1 - 0.052 13.6 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme HypA PF01155.19 KND90730.1 - 0.21 11.6 7.7 2.6 8.1 1.0 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HTH_29 PF13551.6 KND90730.1 - 0.58 10.2 2.1 27 4.9 0.8 2.7 2 0 0 2 2 2 0 Winged helix-turn helix DUF1356 PF07092.12 KND90730.1 - 1.1 8.5 2.3 14 4.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 KND90730.1 - 5.7 6.6 8.5 5.6 6.6 1.7 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 EAP30 PF04157.16 KND90731.1 - 8.5e-74 247.8 0.0 9.6e-74 247.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Serglycin PF04360.12 KND90731.1 - 0.031 14.2 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Serglycin Uricase PF01014.18 KND90735.1 - 9.6e-75 249.1 2.0 7.8e-41 139.4 0.7 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 KND90736.1 - 4.6e-42 143.2 0.0 6.9e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 Arrestin_C PF02752.22 KND90738.1 - 4.5e-16 59.5 0.2 3e-15 56.8 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KND90738.1 - 5.3e-05 23.3 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Snf7 PF03357.21 KND90739.1 - 1.5e-34 119.0 18.8 1.5e-34 119.0 18.8 1.4 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 KND90739.1 - 0.08 12.9 6.8 0.12 12.2 6.8 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway CaMBD PF02888.16 KND90739.1 - 0.092 12.9 1.0 0.092 12.9 1.0 2.2 3 0 0 3 3 3 0 Calmodulin binding domain DDE_Tnp_1 PF01609.21 KND90739.1 - 0.52 9.9 2.7 0.74 9.4 2.7 1.2 1 0 0 1 1 1 0 Transposase DDE domain PspA_IM30 PF04012.12 KND90739.1 - 1 8.9 15.5 2 7.9 5.0 2.2 1 1 1 2 2 2 0 PspA/IM30 family DSBA PF01323.20 KND90739.1 - 1.8 8.3 6.1 3.3 7.4 6.1 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain PP2C PF00481.21 KND90740.1 - 7.6e-60 202.7 0.1 6.8e-49 166.8 0.1 2.9 2 1 0 2 2 2 2 Protein phosphatase 2C A_deaminase PF00962.22 KND90741.1 - 2.5e-27 96.1 0.0 2.9e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_N PF00350.23 KND90742.1 - 1.4e-19 70.8 0.1 3.3e-19 69.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KND90742.1 - 1.6e-10 41.1 0.1 1.2e-09 38.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND90742.1 - 1.7e-07 31.0 1.5 2e-06 27.5 1.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 KND90742.1 - 0.0069 16.6 0.5 1.2 9.4 0.0 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase PMEI PF04043.15 KND90742.1 - 0.0071 16.7 0.0 0.031 14.6 0.0 2.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor RsgA_GTPase PF03193.16 KND90742.1 - 0.016 15.1 0.5 4.6 7.1 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase cobW PF02492.19 KND90742.1 - 0.017 14.7 1.4 0.12 12.0 1.4 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KND90742.1 - 0.078 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KND90742.1 - 0.098 13.2 0.0 0.35 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KND90742.1 - 0.099 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 KND90742.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cofilin_ADF PF00241.20 KND90743.1 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Zn_clus PF00172.18 KND90744.1 - 3.5e-07 30.2 11.9 6.8e-07 29.3 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KND90745.1 - 2e-112 376.4 21.2 3.7e-112 375.5 21.2 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90745.1 - 2e-28 99.3 47.9 1.1e-23 83.7 26.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-3CxxC PF13695.6 KND90746.1 - 5.3e-06 26.8 0.1 8.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding domain Cu_bind_like PF02298.17 KND90747.1 - 0.031 14.3 0.0 0.12 12.5 0.0 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Sporozoite_P67 PF05642.11 KND90747.1 - 0.059 11.4 7.8 0.058 11.5 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 KND90747.1 - 7.4 4.7 6.9 9.9 4.3 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NB-ARC PF00931.22 KND90749.1 - 1.2e-07 31.1 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 KND90749.1 - 1.8e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND90749.1 - 1.1e-05 25.9 0.4 0.00034 21.1 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND90749.1 - 0.00014 22.2 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 KND90749.1 - 0.00017 21.8 0.1 0.00057 20.1 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat IstB_IS21 PF01695.17 KND90749.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 KND90749.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 KND90749.1 - 0.025 14.2 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.6 KND90749.1 - 0.03 14.2 0.0 8.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP54 PF00448.22 KND90749.1 - 0.061 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KND90749.1 - 0.23 11.3 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sda PF08970.10 KND90750.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A ATP13 PF12921.7 KND90751.1 - 1.5e-23 82.8 0.0 5.4e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression Myb_DNA-binding PF00249.31 KND90753.1 - 7.3e-18 64.5 2.3 2.5e-10 40.4 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND90753.1 - 1.9e-10 40.8 0.6 0.00011 22.3 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KND90753.1 - 0.11 12.7 0.6 0.33 11.2 0.1 2.0 2 0 0 2 2 2 0 Rap1 Myb domain Rod-binding PF10135.9 KND90753.1 - 0.18 12.4 0.1 0.46 11.1 0.1 1.7 1 1 0 1 1 1 0 Rod binding protein Myb_DNA-binding PF00249.31 KND90754.1 - 0.0014 18.8 0.3 0.13 12.5 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain YEATS PF03366.16 KND90755.1 - 7.7e-21 73.9 0.2 1.6e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KND90755.1 - 1.6e-05 25.0 0.5 4.6e-05 23.5 0.5 1.8 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Ran_BP1 PF00638.18 KND90756.1 - 8e-48 161.7 3.4 1.6e-47 160.8 3.4 1.5 1 0 0 1 1 1 1 RanBP1 domain VID27_PH PF17747.1 KND90756.1 - 0.086 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 VID27 PH-like domain LAP1C PF05609.12 KND90756.1 - 0.37 9.8 8.8 0.44 9.6 8.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 KND90756.1 - 0.39 10.1 21.4 0.54 9.6 21.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TMEM247 PF15444.6 KND90756.1 - 4.9 7.1 7.9 10 6.1 7.9 1.6 1 1 0 1 1 1 0 Transmembrane protein 247 Chlorosome_CsmC PF11098.8 KND90757.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 Chlorosome envelope protein C Phosducin PF02114.16 KND90758.1 - 1.5e-13 50.3 0.0 1.2e-11 44.1 0.0 2.2 1 1 0 1 1 1 1 Phosducin Citrate_bind PF16114.5 KND90758.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding OHCU_decarbox PF09349.10 KND90759.1 - 3.3e-43 147.8 0.0 4.5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.11 KND90761.1 - 6.7e-32 109.3 2.5 1.5e-31 108.2 2.5 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 KND90761.1 - 2.3e-12 47.2 0.2 0.058 14.3 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90761.1 - 2.4e-10 40.6 0.0 0.27 11.5 0.0 5.3 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KND90761.1 - 0.00024 20.3 0.0 0.0014 17.8 0.0 1.9 1 1 0 1 1 1 1 Coatomer WD associated region V_ATPase_I_N PF18670.1 KND90761.1 - 0.0023 18.3 0.8 0.0086 16.5 0.3 2.1 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain VID27 PF08553.10 KND90761.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Mcl1_mid PF12341.8 KND90761.1 - 0.037 13.4 0.1 6.4 6.0 0.0 2.2 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region zf-Nse PF11789.8 KND90761.1 - 0.1 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 KND90761.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-RING_UBOX PF13445.6 KND90762.1 - 0.0004 20.3 0.8 0.0016 18.4 0.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND90762.1 - 0.00082 19.3 1.6 0.0076 16.2 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KND90762.1 - 0.0018 18.1 3.1 0.032 14.1 0.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KND90762.1 - 0.012 15.5 0.5 0.012 15.5 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90762.1 - 0.062 13.2 2.1 0.22 11.4 2.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbon_6 PF10005.9 KND90762.1 - 0.14 12.9 1.2 0.27 11.9 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 KND90762.1 - 0.67 10.2 2.8 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short_C2 PF13561.6 KND90764.1 - 1.6e-61 207.8 7.8 3.9e-61 206.6 7.8 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90764.1 - 1.7e-47 161.4 2.1 4.1e-47 160.2 2.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90764.1 - 3.6e-13 49.8 2.9 4.3e-12 46.3 2.9 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND90764.1 - 2.5e-06 27.2 0.7 5.8e-06 26.0 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KND90764.1 - 6.3e-06 25.5 0.3 1.5e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 KND90764.1 - 0.0093 16.1 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Adeno_PIX PF03955.14 KND90764.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.2 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) FMO-like PF00743.19 KND90765.1 - 4e-14 51.9 0.1 5.5e-13 48.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KND90765.1 - 7.5e-12 45.3 0.0 1.1e-07 32.0 0.0 3.6 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KND90765.1 - 4.6e-09 35.9 0.0 1.5e-06 27.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KND90765.1 - 3.7e-07 29.7 0.0 1.8e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND90765.1 - 4e-07 29.9 0.1 0.0024 17.5 0.0 3.5 2 2 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KND90765.1 - 7.5e-06 25.4 0.0 0.0059 15.9 0.0 3.2 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 KND90765.1 - 0.00012 21.4 0.0 0.018 14.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND90765.1 - 0.00048 20.1 0.1 0.088 12.8 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 KND90765.1 - 0.01 15.9 0.0 0.081 13.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 KND90765.1 - 0.03 14.7 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KND90765.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KND90765.1 - 0.15 12.3 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KND90765.1 - 0.16 11.2 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain AA_permease PF00324.21 KND90766.1 - 1.2e-112 377.0 47.9 1.5e-112 376.7 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND90766.1 - 9.1e-27 93.9 51.5 1.2e-26 93.6 51.5 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans_2 PF11951.8 KND90767.1 - 9e-54 182.7 0.4 1.1e-53 182.4 0.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 KND90768.1 - 1.3e-57 195.0 3.3 1.5e-57 194.9 3.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90768.1 - 1.5e-38 132.3 0.4 1.8e-38 132.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90768.1 - 1.1e-08 35.2 0.4 1.4e-08 34.8 0.4 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KND90768.1 - 0.016 15.2 1.9 0.19 11.7 1.9 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GCIP PF13324.6 KND90769.1 - 1.9e-20 73.6 0.0 5.6e-20 72.0 0.0 1.7 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting TetR_C_7 PF14246.6 KND90769.1 - 0.0016 18.4 1.0 0.054 13.5 0.1 3.1 3 1 0 3 3 3 1 AefR-like transcriptional repressor, C-terminal domain zf-C3HC4_3 PF13920.6 KND90770.1 - 5.4 6.9 7.6 7.2 6.6 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 KND90770.1 - 7.9 7.2 15.0 0.43 11.2 1.5 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Sugar_tr PF00083.24 KND90771.1 - 5.3e-116 388.1 25.1 6.2e-116 387.9 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90771.1 - 6.2e-26 91.2 51.4 2.9e-22 79.1 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND90771.1 - 0.00037 19.5 9.0 0.12 11.2 2.0 3.0 2 2 1 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 KND90771.1 - 0.00045 18.9 5.0 0.00045 18.9 5.0 3.1 3 1 1 4 4 4 2 MFS/sugar transport protein Glucan_synthase PF02364.15 KND90773.1 - 0 1377.7 0.0 0 1377.1 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KND90773.1 - 1.8e-42 144.8 1.6 6.7e-42 142.9 1.6 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 MerT PF02411.15 KND90773.1 - 0.25 11.4 4.5 0.85 9.7 4.5 1.9 1 0 0 1 1 1 0 MerT mercuric transport protein Aminotran_1_2 PF00155.21 KND90774.1 - 1.7e-33 116.3 0.0 2.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND90774.1 - 0.047 12.2 0.0 0.083 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-C2H2_jaz PF12171.8 KND90775.1 - 5.3e-09 36.1 0.0 9.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 KND90775.1 - 0.01 15.4 0.4 0.025 14.2 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of sodium channel modifier 1 zf-met PF12874.7 KND90775.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DASH_Dam1 PF08653.10 KND90776.1 - 5.6e-28 96.5 2.0 8.1e-28 96.0 2.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 Rhomboid PF01694.22 KND90777.1 - 9.8e-16 58.1 9.6 9.8e-16 58.1 9.6 1.7 1 1 1 2 2 2 1 Rhomboid family Aconitase PF00330.20 KND90778.1 - 4.5e-148 494.1 0.0 5.6e-148 493.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KND90778.1 - 3.8e-43 146.9 0.0 6.3e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Mog1 PF04603.12 KND90779.1 - 2.8e-27 95.8 0.0 5.5e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Adeno_E4_34 PF04528.13 KND90780.1 - 0.019 14.8 0.6 0.046 13.6 0.6 1.6 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region SprT-like PF10263.9 KND90781.1 - 5.7e-40 135.7 2.2 1.1e-39 134.8 2.2 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 KND90781.1 - 2.3e-10 40.2 4.2 5e-10 39.1 4.2 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 KND90781.1 - 0.0015 18.9 0.1 0.0075 16.7 0.1 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box Zn-ribbon_8 PF09723.10 KND90781.1 - 0.028 14.5 1.1 0.067 13.3 1.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Senescence_reg PF04520.13 KND90781.1 - 0.042 14.7 1.0 0.042 14.7 1.0 3.5 2 1 0 2 2 2 0 Senescence regulator DUF4379 PF14311.6 KND90781.1 - 0.22 11.9 4.2 0.16 12.4 1.0 2.5 2 0 0 2 2 2 0 Probable Zinc-ribbon domain YABBY PF04690.13 KND90781.1 - 0.45 11.1 0.0 0.45 11.1 0.0 2.6 3 0 0 3 3 3 0 YABBY protein CRAL_TRIO PF00650.20 KND90782.1 - 1.1e-43 148.7 0.0 1.9e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND90782.1 - 2e-14 53.5 0.1 4.2e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KND90782.1 - 1.7e-06 28.2 0.0 2.8e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 KND90782.1 - 0.071 13.4 0.2 0.22 11.8 0.2 1.9 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain HIT PF01230.23 KND90783.1 - 2.6e-07 31.3 0.0 0.016 16.0 0.1 2.5 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.8 KND90783.1 - 0.00063 20.2 0.0 0.0046 17.4 0.0 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RICTOR_N PF14664.6 KND90784.1 - 1.1e-135 452.4 0.2 3.8e-135 450.7 0.1 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KND90784.1 - 4.6e-38 129.2 0.0 2.2e-35 120.5 0.0 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KND90784.1 - 1.6e-37 128.2 0.1 5e-35 120.2 0.0 3.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KND90784.1 - 1.4e-29 102.1 0.2 6.3e-28 96.8 0.1 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KND90784.1 - 1.1e-16 60.7 8.8 3.6e-16 59.0 8.8 2.0 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.9 KND90784.1 - 0.012 14.2 0.0 1 7.8 0.0 3.2 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit AIP3 PF03915.13 KND90784.1 - 0.038 13.1 1.0 0.064 12.3 1.0 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Uds1 PF15456.6 KND90784.1 - 0.17 12.0 8.3 0.48 10.6 7.6 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF724 PF05266.14 KND90784.1 - 0.19 11.6 4.7 0.29 11.0 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PIEZO PF15917.5 KND90784.1 - 0.27 10.7 2.4 2.3 7.6 2.3 2.2 2 0 0 2 2 2 0 Piezo DUF936 PF06075.12 KND90784.1 - 1.3 7.8 9.7 0.91 8.4 7.9 1.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) DLP_helical PF18709.1 KND90784.1 - 2.5 7.2 5.3 4.8 6.3 5.3 1.4 1 0 0 1 1 1 0 Dynamin-like helical domain Pyr_redox_2 PF07992.14 KND90785.1 - 2.8e-49 167.9 0.2 5.9e-49 166.9 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 KND90785.1 - 2.2e-48 164.3 0.0 1.1e-47 162.0 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND90785.1 - 2.6e-30 105.0 0.0 7.6e-30 103.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyr_redox PF00070.27 KND90785.1 - 9.9e-12 45.3 0.2 4e-10 40.1 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ResIII PF04851.15 KND90785.1 - 3e-05 24.1 0.0 9.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pyr_redox_3 PF13738.6 KND90785.1 - 0.0017 17.6 3.0 0.47 9.6 0.2 3.0 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase UTP25 PF06862.12 KND90785.1 - 0.013 14.3 0.1 0.81 8.4 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KND90785.1 - 0.084 13.2 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 KND90785.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAR2 PF05282.11 KND90787.1 - 2.4e-40 139.0 0.3 1.5e-38 133.1 0.3 2.1 1 1 0 1 1 1 1 AAR2 protein zf-C2H2 PF00096.26 KND90788.1 - 0.19 12.2 0.2 0.41 11.2 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1682 PF07946.14 KND90788.1 - 0.52 9.5 2.9 0.65 9.1 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TAF4 PF05236.14 KND90788.1 - 6.5 6.4 8.2 0.79 9.4 3.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_L32e PF01655.18 KND90789.1 - 1.4e-49 167.0 4.0 1.7e-49 166.8 0.7 2.0 1 1 1 2 2 2 1 Ribosomal protein L32 Ribosomal_S9 PF00380.19 KND90791.1 - 1.1e-32 113.0 0.1 1.3e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 OTU PF02338.19 KND90792.1 - 3.8e-07 30.6 0.0 6.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.25 KND90793.1 - 7.8e-41 138.0 0.4 1.9e-20 72.7 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KND90793.1 - 1.2e-16 60.7 0.2 3.1e-16 59.3 0.2 1.8 1 0 0 1 1 1 1 BAH domain CDC45 PF02724.14 KND90793.1 - 0.00025 19.5 11.3 0.00025 19.5 11.3 2.1 2 0 0 2 2 2 1 CDC45-like protein Mpp10 PF04006.12 KND90793.1 - 0.00043 18.9 4.6 0.00043 18.9 4.6 2.5 3 0 0 3 3 3 1 Mpp10 protein DNA_pol_phi PF04931.13 KND90793.1 - 5.7 4.9 36.1 0.027 12.6 17.5 2.2 2 0 0 2 2 2 0 DNA polymerase phi RTA1 PF04479.13 KND90794.1 - 8.9e-42 143.0 4.4 1.2e-41 142.6 4.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Inp1 PF12634.7 KND90795.1 - 4.7e-43 146.5 0.0 1.1e-42 145.3 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 KND90797.1 - 2.7e-15 57.1 4.7 9.2e-13 48.8 4.7 2.1 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SOG2 PF10428.9 KND90798.1 - 3.2 6.9 8.7 4 6.5 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 KND90799.1 - 6.9e-21 74.5 0.5 1.2e-20 73.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90799.1 - 0.00041 20.4 6.3 0.00081 19.5 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KND90800.1 - 1.9e-38 132.5 0.0 2.7e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KND90800.1 - 0.00023 20.2 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Rtf2 PF04641.12 KND90801.1 - 1.2e-47 162.5 0.4 3.6e-47 161.0 0.4 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 KND90801.1 - 1.2e-05 25.1 0.5 6.3e-05 22.7 0.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KND90801.1 - 0.00024 21.4 0.2 0.00044 20.5 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KND90801.1 - 0.00083 19.3 0.0 0.0065 16.5 0.0 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND90801.1 - 0.001 19.0 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KND90801.1 - 0.0015 18.3 0.4 0.0026 17.5 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KND90801.1 - 0.004 16.9 0.3 0.013 15.3 0.3 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 KND90801.1 - 0.0091 15.7 0.7 0.067 13.0 0.0 2.2 2 0 0 2 2 2 1 RING-like zinc finger Zn-ribbon_8 PF09723.10 KND90801.1 - 0.034 14.3 1.0 0.082 13.0 1.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 KND90801.1 - 0.044 13.6 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRTP PF01366.18 KND90801.1 - 0.074 11.1 1.5 0.096 10.7 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein WLM PF08325.10 KND90801.1 - 0.36 10.9 5.1 0.55 10.3 5.1 1.2 1 0 0 1 1 1 0 WLM domain zf-C2H2 PF00096.26 KND90802.1 - 0.0095 16.3 3.7 0.014 15.8 0.9 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND90802.1 - 0.02 15.7 4.3 0.036 14.9 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ring_hydroxyl_B PF00866.18 KND90802.1 - 0.024 14.7 0.1 0.052 13.6 0.1 1.6 1 0 0 1 1 1 0 Ring hydroxylating beta subunit GTP_EFTU PF00009.27 KND90803.1 - 2.2e-19 69.8 0.0 4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KND90803.1 - 9.7e-09 35.5 0.7 4.2e-08 33.5 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KND90803.1 - 1.7e-05 25.1 0.0 5e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KND90803.1 - 0.0014 18.7 0.3 0.0047 17.0 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND90803.1 - 0.002 18.0 0.7 1 9.3 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KND90803.1 - 0.069 13.2 0.4 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KND90803.1 - 0.11 12.2 0.2 4.5 7.0 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation LSM PF01423.22 KND90804.1 - 1.4e-18 66.3 0.2 1.8e-18 66.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KND90804.1 - 0.11 12.6 0.5 0.2 11.8 0.5 1.5 1 1 0 1 1 1 0 RimP C-terminal SH3 domain CAP PF00188.26 KND90806.1 - 8.9e-15 55.6 4.9 3.8e-14 53.6 4.9 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Aldo_ket_red PF00248.21 KND90807.1 - 3.2e-51 174.3 0.0 4.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family APH PF01636.23 KND90808.1 - 3.3e-21 76.3 0.2 9.7e-21 74.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND90808.1 - 1e-05 25.2 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 KND90808.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KND90808.1 - 0.0016 17.4 0.0 0.013 14.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Kdo PF06293.14 KND90808.1 - 0.011 15.1 0.1 0.47 9.8 0.0 2.7 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KND90808.1 - 0.075 12.4 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain CDC48_N PF02359.18 KND90808.1 - 0.13 12.4 0.0 11 6.3 0.0 3.0 1 1 2 3 3 3 0 Cell division protein 48 (CDC48), N-terminal domain Actin PF00022.19 KND90809.1 - 2e-98 329.7 0.0 2.5e-97 326.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND90809.1 - 0.053 12.3 0.0 0.85 8.4 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Beta-lactamase PF00144.24 KND90810.1 - 1.1e-20 74.2 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase UFD1 PF03152.14 KND90811.1 - 1.2e-28 99.7 0.0 7.5e-22 77.6 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KND90811.1 - 1.9e-06 28.0 1.5 6.4e-06 26.3 0.1 2.6 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zinc_ribbon_9 PF14369.6 KND90811.1 - 0.19 12.0 2.6 9.5 6.6 0.3 3.2 2 0 0 2 2 2 0 zinc-ribbon zf_C2HC_14 PF18574.1 KND90811.1 - 0.2 11.5 0.8 2 8.3 1.1 2.5 2 0 0 2 2 2 0 C2HC Zing finger domain F-box-like PF12937.7 KND90812.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like FtsJ PF01728.19 KND90813.1 - 3.9e-12 46.6 0.0 5.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 KND90814.1 - 4e-08 33.0 0.2 7.3e-08 32.1 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KND90814.1 - 3.5e-05 23.5 0.1 0.00035 20.2 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 KND90814.1 - 0.00024 20.5 0.1 0.0004 19.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND90814.1 - 0.0016 18.4 0.4 0.0056 16.6 0.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND90814.1 - 0.0022 17.3 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KND90814.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KND90814.1 - 0.014 14.2 0.1 0.032 13.0 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 KND90814.1 - 0.14 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase eRF1_1 PF03463.15 KND90815.1 - 8.1e-40 135.8 0.1 1.6e-39 134.8 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 KND90815.1 - 1.6e-18 67.3 0.1 3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KND90815.1 - 3.3e-16 59.8 0.0 5.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 KND90816.1 - 2.2e-29 102.6 0.0 9.1e-27 94.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Thioredoxin PF00085.20 KND90817.1 - 6.6e-21 74.2 0.0 8.3e-21 73.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 KND90817.1 - 2.9e-06 27.1 0.0 3.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KND90817.1 - 2.1e-05 24.0 0.1 2.2e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KND90817.1 - 6.3e-05 23.4 0.0 0.00026 21.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KND90817.1 - 0.0026 17.9 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 KND90817.1 - 0.013 15.8 0.0 0.16 12.3 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_5 PF13743.6 KND90817.1 - 0.054 13.2 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin NdhO PF11910.8 KND90817.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O WD40 PF00400.32 KND90818.1 - 4.1e-20 71.7 13.2 8.4e-06 26.4 0.0 7.5 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90818.1 - 2.1e-05 24.7 0.2 1 9.7 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND90818.1 - 0.007 15.4 0.1 0.12 11.4 0.0 2.6 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AA_permease_2 PF13520.6 KND90819.1 - 9.4e-62 209.2 49.9 1.2e-61 208.9 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND90819.1 - 1.9e-31 109.2 47.1 2.6e-31 108.7 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2569 PF10754.9 KND90819.1 - 0.0054 17.2 8.6 0.0054 17.2 8.6 4.2 4 2 0 4 4 4 1 Protein of unknown function (DUF2569) WD40 PF00400.32 KND90820.1 - 5.9e-16 58.6 7.7 2e-06 28.4 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KND90820.1 - 2.4e-12 46.9 0.1 1.8e-11 44.2 0.0 2.5 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KND90820.1 - 2.6e-09 37.2 1.3 0.00079 19.7 0.1 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KND90820.1 - 0.12 11.3 1.9 0.17 10.8 0.4 1.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain HpcH_HpaI PF03328.14 KND90821.1 - 1.4e-23 83.2 0.0 1.9e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family RCC1 PF00415.18 KND90823.1 - 2.2e-58 194.7 10.6 9.7e-12 45.3 0.1 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND90823.1 - 9.5e-37 124.1 26.8 4.5e-10 39.1 1.2 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 KND90825.1 - 1.4e-36 126.1 28.7 2.2e-36 125.5 28.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 KND90826.1 - 5.8e-28 98.5 1.9 6.9e-28 98.2 1.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND90826.1 - 0.031 14.5 0.2 0.082 13.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND90826.1 - 0.055 12.7 0.2 0.29 10.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND90826.1 - 0.35 10.1 1.2 0.53 9.5 1.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 KND90827.1 - 6.3e-35 120.8 0.0 1.1e-34 120.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND90827.1 - 8.9e-11 42.0 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND90827.1 - 2.6e-05 23.8 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KND90827.1 - 0.003 17.0 0.1 0.0068 15.9 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KND90827.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KND90827.1 - 0.024 15.2 0.1 0.051 14.2 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 KND90827.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KND90827.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KND90827.1 - 0.15 12.3 0.1 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_23 PF13489.6 KND90828.1 - 2e-16 60.2 0.0 3.8e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND90828.1 - 1.6e-09 38.3 0.0 3.7e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND90828.1 - 2.3e-07 30.7 0.4 3.6e-06 26.9 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND90828.1 - 6.7e-05 23.5 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND90828.1 - 0.001 19.8 0.0 0.0037 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND90828.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KND90828.1 - 0.015 14.8 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 KND90828.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KND90828.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Yip1 PF04893.17 KND90830.1 - 7.1e-07 29.1 11.0 0.00022 21.0 7.0 2.6 2 1 0 2 2 2 2 Yip1 domain Sugar_tr PF00083.24 KND90831.1 - 1.3e-93 314.4 16.4 1e-92 311.4 16.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90831.1 - 9.2e-21 74.1 24.2 1.5e-20 73.5 24.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 KND90831.1 - 0.00062 18.3 4.4 0.0012 17.3 4.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector YrhK PF14145.6 KND90831.1 - 0.93 9.4 8.7 0.34 10.8 0.7 3.6 3 0 0 3 3 3 0 YrhK-like protein PAP_assoc PF03828.19 KND90832.1 - 1.2e-13 51.1 0.1 2.3e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KND90832.1 - 7.4e-08 32.6 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain AAA PF00004.29 KND90833.1 - 1.4e-08 35.2 0.2 4.4e-08 33.6 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND90833.1 - 1.7e-06 28.1 0.1 0.0014 18.6 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 KND90833.1 - 0.0013 19.0 0.0 0.0044 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND90833.1 - 0.0014 19.0 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KND90833.1 - 0.056 14.0 0.0 0.21 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KND90833.1 - 0.062 13.2 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 KND90833.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KND90833.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KND90833.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND90833.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Utp8 PF10395.9 KND90834.1 - 1.5e-08 33.6 0.2 5.8e-08 31.7 0.0 1.9 3 0 0 3 3 3 1 Utp8 family Methyltransf_3 PF01596.17 KND90835.1 - 2e-07 30.4 0.2 7.5e-07 28.5 0.2 1.8 1 1 0 1 1 1 1 O-methyltransferase Fungal_trans_2 PF11951.8 KND90836.1 - 2.3e-26 92.5 1.2 8.7e-20 70.9 0.6 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90836.1 - 2.7e-06 27.4 2.4 6.1e-06 26.2 2.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC158 PF15921.5 KND90836.1 - 0.19 9.5 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 HTH_psq PF05225.16 KND90837.1 - 5.5e-08 32.4 0.0 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 KND90837.1 - 0.0085 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 KND90837.1 - 0.0086 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Thiolase_N PF00108.23 KND90837.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF3445 PF11927.8 KND90838.1 - 1.7e-66 224.1 0.0 2.3e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) EutQ PF06249.12 KND90839.1 - 3.5e-11 43.1 0.0 4.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 KND90839.1 - 2.6e-10 39.9 0.1 6.6e-10 38.5 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KND90839.1 - 0.00023 20.8 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KduI PF04962.12 KND90839.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Cupin_6 PF12852.7 KND90839.1 - 0.036 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Lactamase_B_3 PF13483.6 KND90839.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PAN_1 PF00024.26 KND90840.1 - 4.2e-11 42.7 32.2 0.0028 17.6 5.3 5.0 5 1 0 5 5 5 4 PAN domain PAN_4 PF14295.6 KND90840.1 - 0.034 14.1 1.0 0.034 14.1 1.0 5.9 6 0 0 6 6 6 0 PAN domain Herpes_LMP1 PF05297.11 KND90840.1 - 3.8 6.6 4.5 25 3.9 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Sugar_tr PF00083.24 KND90841.1 - 1.4e-78 264.8 18.0 1.7e-78 264.5 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND90841.1 - 9.2e-24 84.0 27.9 4.8e-23 81.7 27.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KND90841.1 - 4.9e-07 28.5 0.8 8.1e-07 27.8 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease_2 PF13520.6 KND90842.1 - 1.1e-44 153.0 50.0 1.4e-44 152.7 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND90842.1 - 4.5e-19 68.4 44.2 6e-19 68.0 44.2 1.1 1 0 0 1 1 1 1 Amino acid permease FAST_1 PF06743.15 KND90842.1 - 0.08 12.9 0.4 7.1 6.7 0.1 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 SIT PF15330.6 KND90843.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3445 PF11927.8 KND90844.1 - 2.3e-74 249.8 0.0 3.5e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF498 PF04430.14 KND90845.1 - 1.7e-28 98.9 0.0 2.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) FAR1 PF03101.15 KND90848.1 - 4.8e-06 27.2 0.1 7.4e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 FAR1 DNA-binding domain Sugarporin_N PF11471.8 KND90848.1 - 0.0018 18.2 1.3 0.007 16.3 0.2 2.4 2 1 1 3 3 3 1 Maltoporin periplasmic N-terminal extension Snapin_Pallidin PF14712.6 KND90848.1 - 0.0036 17.7 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 Snapin/Pallidin XhlA PF10779.9 KND90848.1 - 0.0054 16.9 0.1 0.014 15.6 0.1 1.8 1 1 0 1 1 1 1 Haemolysin XhlA AFT PF08731.11 KND90848.1 - 0.0088 16.4 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor AFT HSBP1 PF06825.12 KND90848.1 - 0.026 14.4 1.4 0.086 12.7 0.6 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Hemagglutinin PF00509.18 KND90848.1 - 0.042 12.3 0.0 0.058 11.8 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin Matrilin_ccoil PF10393.9 KND90848.1 - 0.13 12.1 0.9 1.2 9.1 0.9 2.4 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CCDC53 PF10152.9 KND90848.1 - 0.15 12.5 0.3 0.3 11.5 0.1 1.6 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex YPEB PF14620.6 KND90848.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 2 0 0 2 2 2 0 YpeB sporulation YvrJ PF12841.7 KND90848.1 - 0.33 10.5 1.2 1 8.9 0.7 2.0 2 0 0 2 2 2 0 YvrJ protein family Zn_clus PF00172.18 KND90849.1 - 5.7e-08 32.8 16.2 9.5e-08 32.0 16.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 KND90850.1 - 6.6e-53 180.5 0.0 7.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Rad9 PF04139.13 KND90851.1 - 1.1e-45 156.1 0.5 1.3e-45 155.8 0.5 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 KND90852.1 - 4.1e-28 97.8 11.9 1.1e-12 48.4 0.0 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND90852.1 - 3.1e-19 68.2 17.6 2.2e-07 30.5 1.3 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat 2-Hacid_dh_C PF02826.19 KND90853.1 - 1.6e-05 24.4 0.0 1.6e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KND90853.1 - 3e-05 24.3 0.0 3e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND90853.1 - 0.00045 20.7 0.0 0.00049 20.6 0.0 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 KND90853.1 - 0.0025 17.5 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 KND90853.1 - 0.0039 17.5 0.0 0.005 17.1 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.18 KND90853.1 - 0.0081 16.1 0.0 0.0092 15.9 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KND90853.1 - 0.12 12.9 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain PDH PF02153.17 KND90854.1 - 6.5e-14 51.5 0.0 9.6e-14 51.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase Asp PF00026.23 KND90855.1 - 9.2e-58 196.1 0.7 1.2e-57 195.8 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND90855.1 - 3.4e-15 56.7 2.9 2.4e-13 50.7 1.9 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND90855.1 - 0.0049 17.5 1.7 0.15 12.7 0.1 3.3 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KND90855.1 - 0.014 16.0 0.1 0.087 13.4 0.1 2.5 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KND90855.1 - 0.032 14.0 0.1 5.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal NAD_binding_10 PF13460.6 KND90856.1 - 1.9e-18 67.0 0.0 2.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND90856.1 - 0.033 13.7 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Aldo_ket_red PF00248.21 KND90857.1 - 1.5e-31 109.7 0.0 3.4e-22 79.0 0.0 2.9 2 1 0 2 2 2 2 Aldo/keto reductase family SQS_PSY PF00494.19 KND90858.1 - 7e-61 206.0 0.0 8.6e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 KND90859.1 - 2.7e-70 236.8 0.0 3.7e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KND90859.1 - 1.3e-23 82.7 0.0 2.4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KND90859.1 - 3.1e-14 53.2 0.0 6.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90859.1 - 7.8e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KND90859.1 - 4.1e-05 23.3 3.7 8.9e-05 22.3 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND90859.1 - 0.00013 21.8 5.3 0.00023 20.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90859.1 - 0.00019 21.2 6.6 0.00039 20.2 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND90859.1 - 0.0015 18.8 7.2 0.0039 17.5 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KND90859.1 - 0.0018 18.2 4.1 0.0041 17.1 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND90859.1 - 0.037 14.0 6.8 0.12 12.4 6.8 1.9 1 1 0 1 1 1 0 zinc-RING finger domain UBA_4 PF14555.6 KND90859.1 - 0.046 13.5 0.3 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain AAA_22 PF13401.6 KND90859.1 - 0.09 13.1 0.0 0.98 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-RING_4 PF14570.6 KND90859.1 - 9 6.2 6.9 36 4.2 6.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Tom22 PF04281.13 KND90860.1 - 1.1e-47 161.3 0.0 1.2e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ELFV_dehydrog PF00208.21 KND90861.1 - 4.1e-62 210.1 0.0 6.6e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KND90861.1 - 2.9e-17 61.6 0.0 8.1e-13 46.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase SH3_1 PF00018.28 KND90861.1 - 8.9e-05 22.0 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ELFV_dehydrog_N PF02812.18 KND90861.1 - 0.0098 15.8 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SH3_9 PF14604.6 KND90861.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Nha1_C PF08619.10 KND90863.1 - 3.2e-127 425.6 32.8 4.1e-127 425.2 32.8 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 KND90863.1 - 8.8e-74 248.6 19.8 1.1e-73 248.3 19.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FlgD_ig PF13860.6 KND90863.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 FlgD Ig-like domain YrhC PF14143.6 KND90863.1 - 0.7 10.0 5.7 0.27 11.4 0.4 2.7 3 0 0 3 3 3 0 YrhC-like protein NYD-SP28 PF14772.6 KND90864.1 - 0.052 13.6 1.2 0.14 12.3 1.2 1.6 1 0 0 1 1 1 0 Sperm tail DUF202 PF02656.15 KND90864.1 - 0.074 13.5 0.2 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SAM_2 PF07647.17 KND90865.1 - 1.5e-15 57.0 0.0 2.9e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KND90865.1 - 3.9e-14 52.8 0.0 7.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KND90865.1 - 1.8e-11 44.5 0.0 3.4e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 KND90865.1 - 0.0092 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Aminotran_1_2 PF00155.21 KND90866.1 - 4.9e-59 200.3 0.0 7.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND90866.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.28 KND90867.1 - 1.1e-46 159.3 0.0 1.6e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND90867.1 - 2.2e-06 28.5 0.1 5.9e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KND90867.1 - 0.00018 21.3 1.6 0.00036 20.4 0.2 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF807 PF05660.11 KND90867.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) WD40 PF00400.32 KND90868.1 - 1e-35 121.1 17.6 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90868.1 - 2.9e-15 56.3 0.0 0.00035 20.8 0.1 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND90868.1 - 1.7e-05 23.9 0.2 0.18 10.7 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND90868.1 - 0.00037 20.4 0.0 0.2 11.5 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND90868.1 - 0.0028 17.0 0.0 0.27 10.5 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain DUF2870 PF11069.8 KND90869.1 - 0.23 11.9 0.9 0.34 11.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) PIG-L PF02585.17 KND90870.1 - 3.8e-27 95.5 0.0 5.9e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2461 PF09365.10 KND90871.1 - 0.44 10.5 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) SUIM_assoc PF16619.5 KND90871.1 - 1.5 9.0 10.2 1.1 9.4 3.9 3.1 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Trypsin_2 PF13365.6 KND90872.1 - 1.4e-28 100.7 0.0 1.9e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 KND90872.1 - 2e-05 24.5 0.1 6.8e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 KND90872.1 - 0.0075 15.0 0.0 0.02 13.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S32 PF05579.13 KND90872.1 - 0.016 14.4 0.1 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Metallophos PF00149.28 KND90873.1 - 1.8e-18 67.8 0.0 3.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KND90873.1 - 1.1e-10 42.2 0.1 1e-09 39.1 0.0 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KND90873.1 - 3.2e-10 40.4 0.1 6.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KND90873.1 - 0.0007 20.1 0.1 0.0095 16.4 0.0 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 KND90873.1 - 0.11 12.8 0.2 0.23 11.8 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Ribosomal_S6 PF01250.17 KND90874.1 - 2.3e-20 72.7 0.0 2.9e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3716 PF12511.8 KND90875.1 - 8.1e-08 32.2 8.8 1.4e-07 31.4 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) KIP1 PF07765.12 KND90875.1 - 0.15 12.2 0.9 0.48 10.6 0.9 1.9 1 0 0 1 1 1 0 KIP1-like protein Chs7 PF12271.8 KND90876.1 - 8.5e-123 409.3 12.6 9.8e-123 409.1 12.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KND90876.1 - 0.0017 18.6 0.5 0.0017 18.6 0.5 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF3382) CclA_1 PF16942.5 KND90876.1 - 0.059 13.7 0.2 0.059 13.7 0.2 1.9 2 0 0 2 2 2 0 Putative cyclic bacteriocin Cullin_binding PF03556.15 KND90877.1 - 1.9e-33 115.5 4.5 2e-33 115.4 3.5 1.5 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 KND90877.1 - 8.7e-09 35.1 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain PTCB-BRCT PF12738.7 KND90878.1 - 1e-42 143.9 0.2 1.7e-18 66.3 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KND90878.1 - 5.9e-35 119.5 0.0 2e-11 44.1 0.0 4.4 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND90878.1 - 2.2e-14 53.6 0.0 0.0014 19.0 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KND90878.1 - 9.5e-07 29.0 0.4 0.28 11.5 0.0 3.7 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 KND90878.1 - 0.0034 17.2 0.0 4.1 7.4 0.0 3.5 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KND90878.1 - 0.11 12.5 0.0 12 6.1 0.1 3.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Cyclin PF08613.11 KND90879.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KND90879.1 - 3.9e-05 23.4 0.1 7.2e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2851 PF11013.8 KND90879.1 - 0.17 10.8 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2851) 4HBT_3 PF13622.6 KND90881.1 - 1.6e-21 77.7 0.0 2.9e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily COX5B PF01215.19 KND90883.1 - 5.7e-57 191.0 0.0 8.6e-57 190.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 KND90883.1 - 0.008 15.9 0.2 2.5 8.0 0.0 2.5 2 0 0 2 2 2 2 Topoisomerase DNA binding C4 zinc finger Glyco_transf_15 PF01793.16 KND90884.1 - 1.9e-92 310.0 10.2 1.3e-91 307.3 10.2 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L27A PF00828.19 KND90885.1 - 1.9e-34 119.1 2.1 3.2e-34 118.4 2.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Patatin PF01734.22 KND90885.1 - 0.16 12.1 0.1 2 8.6 0.1 2.1 2 0 0 2 2 2 0 Patatin-like phospholipase SAM_LFY PF01698.16 KND90885.1 - 0.21 11.6 0.1 24 5.0 0.1 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain PX PF00787.24 KND90886.1 - 2.5e-19 69.3 0.1 4.6e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 PX domain ILVD_EDD PF00920.21 KND90887.1 - 5.4e-203 675.3 0.9 6.2e-203 675.1 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family DUF4449 PF14613.6 KND90888.1 - 1.4e-06 28.5 0.1 2.7e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) TrwC PF08751.11 KND90888.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 TrwC relaxase DUF445 PF04286.12 KND90889.1 - 0.018 14.9 0.7 0.051 13.4 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Abhydrolase_6 PF12697.7 KND90890.1 - 8.1e-15 56.0 5.7 8.1e-15 56.0 5.7 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND90890.1 - 3.5e-13 49.8 0.0 2.3e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND90890.1 - 1.4e-12 47.4 0.0 1.2e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DSPc PF00782.20 KND90890.1 - 7.6e-09 35.5 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KND90890.1 - 4e-07 30.4 0.0 8.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 KND90890.1 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KND90890.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KND90890.1 - 0.002 17.9 0.0 0.0063 16.3 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 KND90890.1 - 0.0025 17.9 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 KND90890.1 - 0.0049 16.5 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 KND90890.1 - 0.0094 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.8 KND90890.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) SeqA_N PF17206.3 KND90890.1 - 0.026 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 SeqA protein N-terminal domain LCAT PF02450.15 KND90890.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase VirJ PF06057.11 KND90890.1 - 0.047 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF900 PF05990.12 KND90890.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.18 KND90890.1 - 0.074 12.6 0.0 8.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.13 KND90890.1 - 0.078 12.6 0.0 3.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Alk_phosphatase PF00245.20 KND90891.1 - 1.4e-102 343.7 0.0 1.9e-102 343.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase MFS_1 PF07690.16 KND90891.1 - 1.1e-28 100.2 42.9 4.7e-27 94.8 21.0 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND90891.1 - 4.1e-06 25.9 11.7 4.1e-06 25.9 11.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Metalloenzyme PF01676.18 KND90891.1 - 0.00019 20.9 0.1 0.00036 20.0 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.9 KND90891.1 - 0.06 13.7 0.2 0.25 11.6 0.2 2.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CBS PF00571.28 KND90892.1 - 3.6e-17 62.5 2.9 2.9e-06 27.6 0.0 5.3 5 0 0 5 5 5 4 CBS domain TraV PF09676.10 KND90892.1 - 0.018 16.0 4.0 0.057 14.4 4.0 1.8 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Glyco_hydro_17 PF00332.18 KND90893.1 - 1.9e-08 34.3 0.4 3.6e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 PhageMin_Tail PF10145.9 KND90893.1 - 0.043 13.7 0.1 0.11 12.3 0.0 1.6 2 1 0 2 2 2 0 Phage-related minor tail protein GHL13 PF14883.6 KND90893.1 - 0.062 12.3 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 PAS_9 PF13426.7 KND90894.1 - 1.2e-25 89.8 0.0 3.5e-17 62.6 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 KND90894.1 - 6.9e-20 71.1 0.0 4.2e-12 46.2 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 KND90894.1 - 1.7e-16 60.2 3.2 1.7e-06 28.0 0.0 4.8 4 1 0 4 4 4 3 PAS fold GATA PF00320.27 KND90894.1 - 5.2e-15 54.8 8.9 1e-14 53.8 8.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 KND90894.1 - 2.2e-08 34.2 3.2 0.0052 16.9 0.0 3.3 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KND90894.1 - 2.4e-07 31.0 0.0 0.079 13.2 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_2 PF08446.11 KND90894.1 - 3.4e-05 24.5 0.0 0.017 15.8 0.0 3.4 3 0 0 3 3 3 1 PAS fold DUF1980 PF09323.10 KND90894.1 - 6.2 6.7 5.1 35 4.2 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Importin_rep_4 PF18808.1 KND90895.1 - 8.3e-27 93.3 17.8 5.4e-19 68.3 0.4 6.3 6 1 1 7 7 7 2 Importin repeat Importin_rep_5 PF18816.1 KND90895.1 - 7.6e-22 77.4 3.5 9.2e-22 77.1 0.8 2.7 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 KND90895.1 - 8.1e-20 70.9 7.9 2.7e-08 34.1 0.2 8.0 6 1 2 8 8 7 4 HEAT-like repeat HEAT PF02985.22 KND90895.1 - 6.6e-17 60.2 10.9 0.055 13.7 0.0 10.3 11 0 0 11 11 8 3 HEAT repeat HEAT_2 PF13646.6 KND90895.1 - 2.7e-14 53.3 12.3 4.3e-07 30.2 0.3 7.7 3 2 5 8 8 8 5 HEAT repeats Importin_rep_6 PF18829.1 KND90895.1 - 6.3e-12 45.6 1.4 8.9e-11 41.9 0.2 2.9 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 KND90895.1 - 1.6e-10 41.4 0.8 0.02 15.5 0.0 7.5 5 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 KND90895.1 - 6e-09 35.9 0.0 0.00072 19.4 0.1 4.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 KND90895.1 - 3.4e-08 33.7 0.7 2.3 8.3 0.0 5.4 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 KND90895.1 - 1.5e-07 30.9 0.2 1.5e-07 30.9 0.2 3.7 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DRIM PF07539.12 KND90895.1 - 1.7e-07 30.0 3.3 0.002 16.5 0.5 3.9 3 1 0 4 4 4 1 Down-regulated in metastasis DUF3385 PF11865.8 KND90895.1 - 2.5e-07 30.7 0.7 0.17 11.8 0.0 5.6 4 1 0 5 5 4 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 KND90895.1 - 2.9e-07 30.3 1.6 0.0027 17.3 0.1 5.1 5 1 1 6 6 6 1 CLASP N terminal DUF3535 PF12054.8 KND90895.1 - 0.00029 20.2 1.0 0.0022 17.3 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Telomere_reg-2 PF10193.9 KND90895.1 - 0.00046 20.6 9.5 0.0099 16.3 0.6 4.2 4 0 0 4 4 4 1 Telomere length regulation protein IBN_N PF03810.19 KND90895.1 - 0.00094 19.1 0.1 0.015 15.2 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 KND90895.1 - 0.0033 16.0 1.8 2 6.8 0.1 4.0 4 2 0 5 5 5 2 CAS/CSE protein, C-terminus RTP1_C1 PF10363.9 KND90895.1 - 0.0058 16.8 1.2 0.42 10.8 0.1 4.0 3 1 1 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KND90895.1 - 0.0093 15.3 6.4 0.14 11.4 0.2 3.7 2 1 0 3 3 3 1 V-ATPase subunit H DUF3361 PF11841.8 KND90895.1 - 0.09 12.7 0.8 2.7 7.9 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Arm PF00514.23 KND90895.1 - 0.97 9.6 12.2 0.92 9.6 0.0 5.2 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat Coatomer_WDAD PF04053.14 KND90896.1 - 2.1e-147 491.8 0.0 3.5e-147 491.0 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KND90896.1 - 5.7e-98 328.3 0.0 7.6e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KND90896.1 - 6.1e-35 118.7 18.7 2e-07 31.6 0.3 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90896.1 - 4.1e-08 33.4 0.4 0.0011 19.2 0.0 5.4 3 2 5 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain IPPT PF01715.17 KND90896.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 IPP transferase Nup160 PF11715.8 KND90896.1 - 0.082 11.5 6.0 3.6 6.1 0.2 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Glyco_transf_24 PF18404.1 KND90898.1 - 9.3e-149 494.1 1.1 1.4e-148 493.6 1.1 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KND90898.1 - 2e-69 234.4 0.1 7.4e-68 229.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KND90898.1 - 2.9e-59 200.6 0.3 7.5e-56 189.4 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KND90898.1 - 1.7e-42 145.5 0.3 8.2e-42 143.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KND90898.1 - 1.1e-38 132.3 0.0 3.3e-37 127.4 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KND90898.1 - 1.4e-37 128.2 0.0 2.7e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KND90898.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 SRP-alpha_N PF04086.13 KND90898.1 - 0.47 10.3 3.6 0.76 9.6 3.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sel1 PF08238.12 KND90899.1 - 4.2e-13 49.5 24.5 0.00029 21.4 0.0 7.3 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 KND90899.1 - 0.045 13.6 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TraI_2B PF18340.1 KND90899.1 - 0.1 12.7 1.4 0.15 12.1 0.2 1.9 2 0 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain CSN8_PSD8_EIF3K PF10075.9 KND90900.1 - 1.2e-20 73.9 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KND90900.1 - 0.0081 15.6 0.0 0.014 14.8 0.0 1.3 1 1 0 1 1 1 1 SAC3/GANP family Phos_pyr_kin PF08543.12 KND90901.1 - 4.9e-73 245.5 0.9 5.6e-39 134.0 0.0 2.3 1 1 1 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KND90901.1 - 7.1e-49 166.5 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KND90901.1 - 1.6e-06 27.6 0.0 1.2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Rsa3 PF14615.6 KND90903.1 - 2.9e-17 62.0 0.0 3.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome-assembly protein 3 THUMP PF02926.17 KND90903.1 - 0.07 13.2 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 THUMP domain Ytp1 PF10355.9 KND90904.1 - 1.5e-112 375.3 8.2 2.2e-112 374.8 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KND90904.1 - 1.9e-30 104.7 6.7 1.9e-30 104.7 6.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) BLACT_WH PF17778.1 KND90905.1 - 6.4e-18 64.5 0.0 1.6e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KND90905.1 - 1.4e-14 54.5 4.0 6.8e-13 49.1 4.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KND90905.1 - 9e-06 25.3 0.3 1.6e-05 24.5 0.3 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KND90905.1 - 0.024 14.5 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Mito_carr PF00153.27 KND90906.1 - 2e-45 152.6 0.8 1.4e-17 63.3 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Epimerase PF01370.21 KND90907.1 - 1.6e-13 50.7 0.0 2.9e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KND90907.1 - 4.5e-13 49.3 0.1 6.7e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KND90907.1 - 9.5e-13 48.4 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND90907.1 - 1.1e-08 34.4 0.0 2.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KND90907.1 - 9.7e-07 28.5 0.1 1.5e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KND90907.1 - 9.8e-06 24.9 0.0 2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KND90907.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KND90907.1 - 0.0046 16.2 0.5 0.6 9.2 0.1 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 KND90907.1 - 0.0087 16.0 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 1 KR domain adh_short_C2 PF13561.6 KND90907.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase UCH PF00443.29 KND90908.1 - 3.8e-46 157.7 3.1 5e-46 157.3 3.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND90908.1 - 1e-30 107.5 6.6 1.6e-30 106.8 6.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rad54_N PF08658.10 KND90909.1 - 1.4e-57 194.7 0.7 1.6e-56 191.3 1.0 2.2 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 KND90909.1 - 1.5e-57 194.9 0.0 2.5e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND90909.1 - 3.6e-16 59.5 0.0 1.2e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND90909.1 - 2.4e-11 43.9 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KND90909.1 - 2.6e-05 23.6 0.0 0.00012 21.4 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Gaa1 PF04114.14 KND90910.1 - 4.9e-165 550.3 2.2 5.9e-165 550.0 2.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 KND90911.1 - 3.9e-09 37.0 0.0 9.3e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KND90911.1 - 2.5e-08 33.4 1.3 4.8e-08 32.4 1.3 1.4 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KND90911.1 - 0.015 14.9 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) YhhN PF07947.14 KND90912.1 - 5.2e-37 127.2 20.1 6.5e-37 126.9 20.1 1.1 1 0 0 1 1 1 1 YhhN family adh_short_C2 PF13561.6 KND90913.1 - 4.2e-62 209.8 0.5 4.8e-62 209.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90913.1 - 1.4e-40 138.9 0.6 1.7e-40 138.6 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90913.1 - 4e-14 52.9 0.3 5.9e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Noc2 PF03715.13 KND90917.1 - 6.3e-127 422.9 0.0 1e-126 422.2 0.0 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 KND90917.1 - 0.0066 14.7 0.1 0.0066 14.7 0.1 3.2 2 1 1 3 3 3 1 Nop14-like family Cep57_MT_bd PF06657.13 KND90918.1 - 1.2e-29 102.5 0.1 1.2e-29 102.5 0.1 5.4 5 0 0 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KND90918.1 - 1.8e-25 88.8 18.5 4.7e-14 52.2 7.1 6.0 4 1 2 6 6 6 3 Centrosome localisation domain of PPC89 KASH_CCD PF14662.6 KND90918.1 - 1.5e-05 25.0 53.8 0.00012 22.0 15.6 4.8 2 1 2 4 4 4 2 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 KND90918.1 - 0.0045 17.9 11.9 0.0045 17.9 11.9 5.6 3 1 2 6 6 6 1 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 KND90918.1 - 0.0063 16.9 58.5 0.5 10.8 5.3 7.8 2 1 4 7 7 7 3 Cell division protein ZapB CENP-F_leu_zip PF10473.9 KND90918.1 - 0.083 12.9 56.0 0.038 14.0 15.2 4.1 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 KND90918.1 - 1.3 9.5 58.9 0.58 10.7 16.0 4.9 3 1 1 5 5 5 0 Apg6 coiled-coil region Nmad5 PF18757.1 KND90918.1 - 3 8.0 25.1 0.35 11.0 2.0 3.3 2 1 1 3 3 3 0 Nucleotide modification associated domain 5 bZIP_1 PF00170.21 KND90918.1 - 5.3 7.2 48.2 0.13 12.3 3.3 7.9 6 2 2 9 9 9 0 bZIP transcription factor Sbi-IV PF11621.8 KND90918.1 - 5.6 7.4 15.8 5.9 7.3 0.3 4.2 4 0 0 4 4 4 0 C3 binding domain 4 of IgG-bind protein SBI HALZ PF02183.18 KND90918.1 - 7.7 6.8 53.5 0.096 12.9 5.3 9.1 6 1 3 9 9 9 0 Homeobox associated leucine zipper Fungal_TACC PF12709.7 KND90918.1 - 8.8 6.9 36.7 0.5 10.8 0.4 7.4 2 1 5 8 8 8 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2353 PF09789.9 KND90918.1 - 8.9 5.6 60.6 0.12 11.7 10.1 3.5 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) HeLo PF14479.6 KND90919.1 - 1.6e-24 86.9 0.0 1.7e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation EVE PF01878.18 KND90920.1 - 8.7e-43 145.8 0.0 1.6e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 EVE domain SRP-alpha_N PF04086.13 KND90920.1 - 7.4 6.4 14.6 10 5.9 14.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3591 PF12157.8 KND90921.1 - 1.5e-164 547.9 0.3 2.4e-164 547.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KND90921.1 - 0.0041 17.1 0.7 0.0087 16.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KND90921.1 - 0.0078 16.0 1.2 0.02 14.7 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle 2OG-FeII_Oxy PF03171.20 KND90923.1 - 0.0052 17.3 0.0 0.012 16.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 KND90924.1 - 5.9e-46 156.6 0.4 1.2e-45 155.6 0.4 1.5 1 1 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KND90924.1 - 0.0011 19.1 0.0 0.0053 17.0 0.0 1.9 1 1 1 2 2 2 1 Fascin domain bZIP_Maf PF03131.17 KND90924.1 - 0.077 13.5 2.2 0.077 13.5 2.2 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.32 KND90925.1 - 7.7e-09 36.0 0.3 0.23 12.4 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Mito_carr PF00153.27 KND90926.1 - 6.5e-63 208.7 4.5 1e-20 73.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L24e PF01246.20 KND90927.1 - 1.1e-31 108.9 5.3 2e-31 108.0 5.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e IF2_N PF04760.15 KND90927.1 - 0.092 12.6 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MIT PF04212.18 KND90928.1 - 0.031 14.3 0.1 0.052 13.6 0.1 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 KND90928.1 - 0.04 14.0 0.4 0.18 12.0 0.4 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat GMC_oxred_C PF05199.13 KND90930.1 - 3.3e-36 125.0 0.1 5.1e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KND90930.1 - 6.4e-35 121.0 0.1 1.7e-34 119.6 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND90931.1 - 3.5e-36 124.9 0.1 5.5e-36 124.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KND90931.1 - 7.1e-35 120.8 0.0 2e-34 119.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase ADH_N PF08240.12 KND90933.1 - 7.5e-08 32.2 2.7 1.3e-07 31.5 0.4 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KND90933.1 - 6.5e-06 27.2 0.0 1.4e-05 26.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-RING_2 PF13639.6 KND90934.1 - 4.2e-08 33.4 10.4 4.2e-08 33.4 10.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 KND90934.1 - 2.7e-06 27.3 3.3 2.7e-06 27.3 3.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KND90934.1 - 0.00017 21.7 13.9 0.0021 18.2 9.3 2.8 2 1 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KND90934.1 - 0.0015 18.8 7.8 0.0015 18.8 7.8 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KND90934.1 - 0.018 15.0 9.6 0.018 15.0 9.6 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND90934.1 - 0.023 14.7 7.7 0.023 14.7 7.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING-like PF08746.11 KND90934.1 - 0.032 14.5 3.8 0.032 14.5 3.8 2.1 2 0 0 2 2 2 0 RING-like domain Prok-RING_4 PF14447.6 KND90934.1 - 0.13 12.1 8.0 0.15 11.9 1.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KND90934.1 - 0.65 10.2 16.5 0.038 14.1 10.9 2.0 2 0 0 2 2 1 0 RING-variant domain Rib_recp_KP_reg PF05104.12 KND90934.1 - 1.2 10.2 6.3 2 9.4 6.3 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region zf-RING_4 PF14570.6 KND90934.1 - 2 8.3 14.7 0.093 12.5 9.0 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KND90934.1 - 2 8.6 7.0 2.2 8.4 4.8 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_3 PF13920.6 KND90934.1 - 4.6 7.2 13.2 0.11 12.4 6.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND90934.1 - 7.2 6.5 18.3 1.6 8.7 10.4 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND90934.1 - 8.1 6.4 19.3 0.12 12.3 9.6 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NAPRTase PF04095.16 KND90935.1 - 5.6e-59 199.7 0.2 8.6e-32 110.7 0.3 2.1 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KND90935.1 - 2.8e-34 118.2 0.0 5.4e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WSC PF01822.19 KND90936.1 - 9.8e-19 67.3 6.8 2.4e-18 66.1 6.8 1.7 1 0 0 1 1 1 1 WSC domain ENTH PF01417.20 KND90936.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 ENTH domain CactinC_cactus PF09732.9 KND90937.1 - 1e-56 190.3 5.0 1.5e-56 189.7 5.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 KND90937.1 - 5.3e-55 186.2 1.2 8.1e-55 185.6 1.2 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin SF3A2 PF16835.5 KND90937.1 - 0.024 15.0 0.1 0.078 13.4 0.0 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Fungal_trans PF04082.18 KND90938.1 - 1.6e-20 73.3 0.0 5.1e-20 71.6 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90938.1 - 1.1e-08 35.0 9.9 2e-08 34.2 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tup_N PF08581.10 KND90938.1 - 0.43 10.9 1.9 14 6.1 0.1 2.7 2 0 0 2 2 2 0 Tup N-terminal Fungal_trans PF04082.18 KND90940.1 - 1.1e-10 41.0 0.0 2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND90940.1 - 1.4e-06 28.3 9.6 1.4e-06 28.3 9.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4199 PF13858.6 KND90940.1 - 0.22 11.9 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) p450 PF00067.22 KND90942.1 - 1e-10 41.0 0.0 7.1e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF1290 PF06947.12 KND90942.1 - 0.18 11.9 0.2 0.48 10.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) Thioredoxin_4 PF13462.6 KND90943.1 - 0.00037 20.7 0.0 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 KND90943.1 - 0.003 17.4 3.1 0.13 12.0 0.3 2.5 1 1 1 2 2 2 2 DSBA-like thioredoxin domain Phage_TAC_6 PF09550.10 KND90943.1 - 0.021 15.2 0.2 0.042 14.3 0.2 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Abhydrolase_3 PF07859.13 KND90944.1 - 9.6e-38 130.1 0.0 1.2e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND90944.1 - 3.1e-10 39.5 0.0 3.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase Thioesterase PF00975.20 KND90944.1 - 0.0029 17.7 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 KND90944.1 - 0.0069 15.7 0.0 0.059 12.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 KND90944.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Peptidase_S9 PF00326.21 KND90944.1 - 0.036 13.6 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND90944.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold NACHT PF05729.12 KND90946.1 - 1.2e-11 44.8 2.7 0.00063 19.7 0.1 4.5 4 1 0 4 4 4 2 NACHT domain AAA_22 PF13401.6 KND90946.1 - 4.9e-05 23.6 0.0 0.0064 16.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 KND90946.1 - 0.00062 20.1 0.0 0.0081 16.5 0.0 2.7 3 0 0 3 3 3 1 RNA helicase NB-ARC PF00931.22 KND90946.1 - 0.0011 18.2 0.4 0.0028 16.9 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 KND90946.1 - 0.0019 18.6 0.0 0.015 15.7 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain UPF0128 PF03673.13 KND90946.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) ABC_tran PF00005.27 KND90946.1 - 0.035 14.6 0.0 0.09 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 KND90946.1 - 0.068 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 KND90946.1 - 0.069 13.6 0.0 9.2 6.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KND90946.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KND90946.1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain PNP_UDP_1 PF01048.20 KND90947.1 - 6.6e-14 51.7 1.3 3.7e-13 49.3 1.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ost5 PF05251.12 KND90948.1 - 0.0082 16.4 0.3 0.014 15.7 0.3 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 FecCD PF01032.18 KND90948.1 - 0.047 12.7 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 FecCD transport family DUF5381 PF17353.2 KND90948.1 - 0.064 13.0 0.4 0.081 12.7 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5381) PNP_UDP_1 PF01048.20 KND90949.1 - 1.1e-08 34.6 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Slx4 PF09494.10 KND90951.1 - 2e-24 85.3 0.1 3.5e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.19 KND90951.1 - 0.0013 18.4 16.2 0.2 11.6 5.0 4.4 2 0 0 2 2 2 2 AT hook motif Ribosomal_S21e PF01249.18 KND90952.1 - 1.9e-40 136.9 0.1 2.3e-40 136.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 KND90953.1 - 1.3e-82 276.2 0.1 2.4e-82 275.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KND90953.1 - 1.5e-39 135.6 0.0 2.6e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 KND90953.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family XLF PF09302.11 KND90954.1 - 6e-48 163.4 0.1 2.5e-47 161.3 0.0 2.0 2 1 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 KND90955.1 - 5.4e-19 68.2 0.0 9.6e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain WD40 PF00400.32 KND90956.1 - 1.5e-11 44.6 15.2 1.3 10.0 0.4 9.2 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND90956.1 - 5e-07 29.9 2.1 0.0057 16.9 0.1 5.9 5 2 2 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND90956.1 - 0.005 15.8 0.3 2.9 6.7 0.0 3.8 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KND90956.1 - 0.19 10.0 0.1 0.55 8.5 0.1 1.7 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz CDP-OH_P_transf PF01066.21 KND90957.1 - 1.4e-16 61.0 0.4 1.4e-16 61.0 0.4 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase PLDc_2 PF13091.6 KND90958.1 - 1.8e-19 69.9 0.0 2.4e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KND90958.1 - 1.2e-05 25.3 0.2 0.0018 18.4 0.0 2.7 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 KND90958.1 - 0.015 14.5 0.0 0.062 12.5 0.0 2.0 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB MTTB PF06253.11 KND90958.1 - 0.041 11.9 0.1 0.063 11.3 0.1 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) PFL-like PF02901.15 KND90958.1 - 0.084 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Pyruvate formate lyase-like F-box PF00646.33 KND90959.1 - 0.00041 20.1 1.1 0.00085 19.1 1.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KND90959.1 - 0.019 14.9 0.7 0.019 14.9 0.7 1.8 2 0 0 2 2 2 0 F-box-like FhuF_C PF11575.8 KND90959.1 - 0.13 12.2 0.4 0.13 12.2 0.4 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Peptidase_M28 PF04389.17 KND90960.1 - 3.5e-31 108.4 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Epimerase PF01370.21 KND90962.1 - 3.2e-17 62.8 0.0 5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND90962.1 - 9.3e-10 38.0 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KND90962.1 - 5.2e-09 36.2 2.4 4.6e-08 33.2 2.4 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KND90962.1 - 2.3e-05 23.7 0.0 4.1e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KND90962.1 - 3.7e-05 23.4 0.1 6.1e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KND90962.1 - 0.0003 20.3 0.2 0.00071 19.1 0.2 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KND90962.1 - 0.0029 17.6 0.1 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KND90962.1 - 0.0033 16.6 0.1 1.8 7.6 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KND90962.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KND90962.1 - 0.051 13.0 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase EamA PF00892.20 KND90963.1 - 0.00063 19.9 27.9 0.00068 19.8 10.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family IF4E PF01652.18 KND90964.1 - 5.1e-55 185.6 0.1 6.5e-55 185.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Translin PF01997.16 KND90965.1 - 4.8e-62 209.6 0.0 5.7e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Hemerythrin PF01814.23 KND90965.1 - 0.094 13.3 2.1 0.43 11.2 2.1 2.2 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Mannosyl_trans PF05007.13 KND90966.1 - 3.8e-80 269.5 10.3 4.9e-80 269.1 10.3 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KND90966.1 - 4.2e-10 39.2 12.2 2.7e-09 36.6 12.2 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KND90966.1 - 0.59 9.8 43.0 0.013 15.3 33.4 2.9 2 1 1 3 3 3 0 Glycosyltransferase family 87 SQS_PSY PF00494.19 KND90967.1 - 3.1e-38 131.8 0.0 5.8e-38 130.9 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase SpoIIM PF01944.17 KND90967.1 - 0.24 11.4 2.0 0.43 10.6 2.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein M RmlD_sub_bind PF04321.17 KND90968.1 - 4.1e-11 42.5 0.0 1.8e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KND90968.1 - 7e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KND90968.1 - 0.00015 21.0 0.0 0.00033 19.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KND90968.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 KND90969.1 - 0.00026 20.8 0.1 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.22 KND90970.1 - 1.5e-32 113.0 16.7 3.2e-32 112.0 16.7 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND90970.1 - 0.0071 17.0 0.0 0.012 16.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ELH PF02323.15 KND90970.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor Cyt-b5 PF00173.28 KND90972.1 - 1.7e-15 56.9 0.0 2.4e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ-X PF14308.6 KND90973.1 - 1.3e-76 256.7 2.3 1.3e-76 256.7 2.3 2.7 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KND90973.1 - 5.2e-26 90.6 1.0 1.3e-25 89.2 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Ost5 PF05251.12 KND90974.1 - 5.1e-07 29.9 3.2 7.1e-07 29.4 3.2 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 KND90975.1 - 1.6e-71 240.6 0.0 1.9e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 ANAPC_CDC26 PF10471.9 KND90977.1 - 7.7e-14 52.3 1.2 8.9e-14 52.1 1.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 PQ-loop PF04193.14 KND90979.1 - 1.1e-24 86.0 2.8 1.5e-14 53.5 0.2 2.5 2 0 0 2 2 2 2 PQ loop repeat ADH_N PF08240.12 KND90980.1 - 9.4e-28 96.3 5.3 1.4e-27 95.7 4.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND90980.1 - 6.5e-19 68.2 0.1 1.1e-18 67.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND90980.1 - 0.0008 20.5 0.0 0.0018 19.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND90980.1 - 0.026 13.8 0.6 0.043 13.1 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_trans_4_2 PF13477.6 KND90980.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like TrkA_N PF02254.18 KND90980.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AMP-binding PF00501.28 KND90981.1 - 6.5e-70 235.8 0.0 1.9e-69 234.3 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND90981.1 - 2.6e-12 47.6 2.9 4.7e-12 46.7 0.1 2.7 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain FYVE_2 PF02318.16 KND90982.1 - 0.086 13.1 3.1 0.096 12.9 1.7 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger Thiolase_N PF00108.23 KND90983.1 - 3.8e-88 295.2 0.6 5.1e-88 294.8 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND90983.1 - 1.3e-44 150.8 0.8 3.6e-44 149.3 0.6 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND90983.1 - 1.5e-05 24.7 1.9 0.00016 21.4 1.3 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KND90983.1 - 0.52 10.2 3.1 12 5.9 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 KND90984.1 - 6e-56 189.6 0.0 6.9e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND90984.1 - 4.3e-45 153.6 0.0 5.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND90984.1 - 9.8e-11 41.9 0.0 1.4e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND90984.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KND90984.1 - 0.12 11.7 0.0 0.62 9.4 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KND90985.1 - 3.7e-34 117.9 0.0 5.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND90985.1 - 5.9e-26 91.5 0.1 8.2e-26 91.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND90985.1 - 6.1e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KND90985.1 - 1.4e-05 24.6 0.0 2.7e-05 23.7 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KND90985.1 - 2.4e-05 24.3 0.5 7.5e-05 22.7 0.2 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KND90985.1 - 0.0024 17.4 0.2 0.0037 16.8 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KND90985.1 - 0.026 14.4 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 KND90985.1 - 0.033 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KND90985.1 - 0.091 13.4 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.16 KND90986.1 - 2e-34 119.1 68.0 5e-25 88.2 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KND90986.1 - 1.3e-09 37.9 26.1 1.7e-09 37.5 26.1 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KND90986.1 - 0.037 12.9 27.0 0.44 9.3 15.3 2.4 1 1 1 2 2 2 0 MFS_1 like family MFS_1 PF07690.16 KND90988.1 - 3.1e-16 59.3 50.4 3.1e-16 59.3 50.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily PIP5K PF01504.18 KND90989.1 - 3.9e-26 91.9 0.0 2.4e-17 63.0 0.0 3.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KND90989.1 - 6.4e-23 81.1 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KND90989.1 - 5.5e-15 55.3 10.0 1.4e-14 53.9 10.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF3157 PF11355.8 KND90989.1 - 1.7 8.2 3.6 3.7 7.1 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) C1_1 PF00130.22 KND90989.1 - 9.3 6.2 10.9 2.4 8.1 6.7 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MMM1 PF10296.9 KND90990.1 - 0.0013 17.8 0.0 0.0032 16.6 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PBP1_TM PF14812.6 KND90990.1 - 0.33 11.3 4.3 3.6 8.0 0.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_trans_1_4 PF13692.6 KND90991.1 - 4.6e-15 56.2 0.1 1.1e-14 55.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KND90991.1 - 5.3e-15 55.4 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 KND90991.1 - 3.8e-05 23.6 0.0 0.00042 20.1 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) p53-inducible11 PF14936.6 KND90991.1 - 0.15 12.1 1.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 RHS_repeat PF05593.14 KND90991.1 - 0.69 10.5 4.1 0.52 10.9 0.3 2.6 2 0 0 2 2 2 0 RHS Repeat Zip PF02535.22 KND90993.1 - 7.8e-54 183.1 0.2 1.8e-53 181.9 0.2 1.6 1 0 0 1 1 1 1 ZIP Zinc transporter STI1 PF17830.1 KND90993.1 - 6.2e-36 122.1 14.9 4.8e-20 71.3 4.0 2.8 2 0 0 2 2 2 2 STI1 domain TPR_1 PF00515.28 KND90993.1 - 1.5e-35 119.5 28.8 7.8e-07 28.7 0.9 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KND90993.1 - 1.8e-29 99.4 25.8 2.3e-05 24.2 0.2 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 KND90993.1 - 8.3e-16 57.4 19.6 0.01 15.5 0.2 7.1 6 1 0 6 6 6 5 TPR repeat TPR_16 PF13432.6 KND90993.1 - 1.2e-12 48.2 3.2 0.0011 19.6 0.0 5.6 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND90993.1 - 4.3e-12 46.1 11.6 4.3e-10 39.7 0.9 4.6 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND90993.1 - 2.1e-11 43.6 3.8 1.6 9.7 0.0 8.0 4 3 4 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND90993.1 - 3.4e-10 39.6 4.1 1.8 9.2 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND90993.1 - 3.9e-09 36.9 9.1 0.018 15.5 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND90993.1 - 4.3e-09 35.8 0.9 0.12 12.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND90993.1 - 2.4e-08 34.0 0.1 0.021 14.9 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND90993.1 - 2.8e-08 33.3 30.7 0.0021 18.1 0.3 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KND90993.1 - 0.00039 20.2 4.9 0.017 15.0 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND90993.1 - 0.006 17.1 10.3 6.2 7.7 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 KND90993.1 - 0.011 15.0 5.1 0.02 14.1 0.9 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KND90993.1 - 0.021 14.9 6.7 7.1 6.8 0.1 4.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 KND90993.1 - 0.063 13.5 5.2 0.26 11.6 1.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GerD PF17898.1 KND90993.1 - 0.083 12.8 6.3 2.9 7.9 1.1 2.8 2 0 0 2 2 2 0 Spore germination GerD central core domain TPR_3 PF07720.12 KND90993.1 - 2.7 8.1 12.2 3.8 7.6 0.6 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat FMO-like PF00743.19 KND90994.1 - 4.9e-14 51.7 0.0 2.9e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KND90994.1 - 1.6e-11 44.0 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND90994.1 - 2.2e-11 43.6 0.0 5e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND90994.1 - 3e-10 40.2 0.0 4.6e-08 33.2 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND90994.1 - 3.2e-07 30.3 1.2 0.055 13.1 0.0 3.6 3 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 KND90994.1 - 4.1e-07 29.5 0.1 1.5e-05 24.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KND90994.1 - 5.9e-07 29.0 0.0 0.00018 20.8 0.0 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 KND90994.1 - 1.7e-06 28.5 0.6 0.018 15.6 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND90994.1 - 0.00047 20.2 1.5 14 5.6 0.2 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Mqo PF06039.15 KND90994.1 - 0.011 14.3 0.1 0.25 9.8 0.0 2.6 3 1 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KND90994.1 - 0.011 14.8 0.0 0.25 10.4 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.20 KND90994.1 - 0.012 15.7 0.1 0.24 11.4 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 KND90994.1 - 0.013 14.8 0.2 0.031 13.6 0.0 1.7 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 KND90994.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KND90994.1 - 0.038 13.0 0.0 0.78 8.7 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KND90994.1 - 0.092 11.8 0.1 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KND90994.1 - 0.15 11.4 0.1 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KND90994.1 - 0.19 10.4 0.1 5.7 5.5 0.0 2.8 3 0 0 3 3 3 0 HI0933-like protein Rhodanese PF00581.20 KND90996.1 - 3.1e-06 27.7 0.0 5.3e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain LSM PF01423.22 KND90997.1 - 3.9e-21 74.5 0.1 4.4e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF4813 PF16072.5 KND90997.1 - 0.87 9.2 4.4 1 9.0 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF3844 PF12955.7 KND90998.1 - 7.9e-32 109.5 0.6 1.4e-31 108.8 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Zn_clus PF00172.18 KND90999.1 - 0.3 11.2 4.5 0.75 10.0 4.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Bromodomain PF00439.25 KND91000.1 - 5.8e-31 106.4 0.2 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Merozoite_SPAM PF07133.11 KND91000.1 - 0.07 13.1 9.2 0.11 12.5 9.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 KND91000.1 - 0.11 10.7 5.0 0.17 10.2 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KND91000.1 - 0.31 9.2 5.9 0.45 8.7 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KND91000.1 - 1.8 8.0 7.1 3.5 7.1 7.1 1.5 1 0 0 1 1 1 0 PPP4R2 Astro_capsid_p PF12226.8 KND91000.1 - 2.1 7.4 5.0 3.2 6.8 5.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sporozoite_P67 PF05642.11 KND91000.1 - 3.6 5.5 11.3 1.8 6.6 1.3 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.18 KND91000.1 - 4.6 7.1 6.9 0.53 10.1 1.9 2.0 2 0 0 2 2 2 0 Myc amino-terminal region p450 PF00067.22 KND91002.1 - 3.2e-69 233.9 0.0 4.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 KND91003.1 - 3e-19 70.0 0.5 4e-19 69.6 0.5 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KND91003.1 - 7.6e-05 23.1 0.2 0.00012 22.5 0.2 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase MFS_1 PF07690.16 KND91004.1 - 9.9e-41 139.8 53.5 1.4e-40 139.4 50.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 KND91005.1 - 2.1e-49 168.8 0.1 2.4e-49 168.6 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 KND91006.1 - 2.6e-73 247.4 19.5 2.9e-73 247.2 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91006.1 - 6e-13 48.4 36.0 6e-13 48.4 36.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Bacillus_PapR PF05968.11 KND91006.1 - 1 9.3 6.4 5.6 6.9 0.7 2.9 2 0 0 2 2 2 0 Bacillus PapR protein Sugar_tr PF00083.24 KND91007.1 - 4.8e-82 276.2 26.6 5.5e-82 276.0 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91007.1 - 2.7e-12 46.3 29.2 2.7e-12 46.3 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 KND91007.1 - 0.13 12.4 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Sulfate_transp PF00916.20 KND91008.1 - 5.3e-89 298.6 10.6 7e-89 298.2 10.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND91008.1 - 2.3e-11 43.4 0.0 4.7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KND91008.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 STAS domain DUF5493 PF17597.2 KND91008.1 - 2.4 8.5 7.0 0.5 10.7 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5493) Cupin_1 PF00190.22 KND91009.1 - 8.9e-40 135.8 0.0 1.2e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KND91009.1 - 3.3e-26 90.8 1.0 2.9e-12 46.1 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KND91009.1 - 3.8e-09 36.1 0.1 0.00032 20.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KND91009.1 - 2.8e-07 30.5 0.1 0.0005 20.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KND91009.1 - 0.00041 20.3 0.0 0.065 13.1 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KND91009.1 - 0.031 14.5 0.5 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 KND91009.1 - 0.058 13.0 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KND91009.1 - 0.11 12.4 0.1 0.72 9.8 0.1 2.4 1 1 0 1 1 1 0 ChrR Cupin-like domain DUF1275 PF06912.11 KND91010.1 - 1.5e-43 148.9 14.2 1.8e-43 148.7 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 KND91010.1 - 0.079 11.9 17.3 0.097 11.6 4.0 2.9 2 1 1 3 3 3 0 Major Facilitator Superfamily DUF3040 PF11239.8 KND91010.1 - 0.69 10.2 6.7 10 6.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) MFS_1 PF07690.16 KND91011.1 - 1.2e-06 27.7 1.0 1.5e-06 27.4 1.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DcuA_DcuB PF03605.14 KND91011.1 - 0.042 12.7 0.1 0.048 12.6 0.1 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Nuc_sug_transp PF04142.15 KND91011.1 - 0.068 12.3 0.2 0.087 12.0 0.2 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter Phage_holin_3_6 PF07332.11 KND91011.1 - 0.31 11.1 2.4 0.43 10.6 2.4 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 KND91012.1 - 7.1e-23 81.0 1.2 1.2e-22 80.2 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91012.1 - 5.7e-11 42.4 9.9 1.4e-10 41.1 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_UL25 PF01499.16 KND91012.1 - 0.21 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family PKcGMP_CC PF16808.5 KND91012.1 - 0.38 10.7 2.1 0.52 10.2 1.0 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 KND91013.1 - 7.6e-31 107.4 0.0 3.4e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND91013.1 - 1.1e-10 41.3 0.0 0.00026 20.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KND91013.1 - 0.033 14.1 0.2 0.17 11.8 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KND91013.1 - 0.075 12.3 0.1 4.5 6.5 0.0 3.2 4 0 0 4 4 4 0 Kinase-like Thioredoxin PF00085.20 KND91014.1 - 1.3e-24 86.1 0.0 1.8e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KND91014.1 - 1.7e-06 28.4 0.1 7.8e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KND91014.1 - 2.3e-05 23.9 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KND91014.1 - 2.8e-05 24.3 0.0 0.00044 20.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KND91014.1 - 0.0014 18.4 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KND91014.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 KND91014.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 KND91014.1 - 0.0058 16.8 0.1 0.0093 16.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KND91014.1 - 0.024 14.9 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin AhpC-TSA PF00578.21 KND91014.1 - 0.14 12.1 0.1 3.4 7.6 0.0 2.1 1 1 0 2 2 2 0 AhpC/TSA family Thioredoxin_5 PF13743.6 KND91014.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin MFS_1 PF07690.16 KND91015.1 - 3.2e-31 108.5 56.4 1.8e-29 102.8 56.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 KND91015.1 - 0.005 15.5 21.5 0.013 14.1 12.9 3.1 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like OATP PF03137.20 KND91015.1 - 0.19 10.0 14.6 0.48 8.6 2.0 3.4 2 2 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KND91016.1 - 1.8e-39 135.7 43.0 1.8e-39 135.7 43.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PsaL PF02605.15 KND91016.1 - 0.21 11.2 3.1 2.6 7.7 3.1 2.5 1 1 0 1 1 1 0 Photosystem I reaction centre subunit XI Sugar_tr PF00083.24 KND91016.1 - 0.41 9.4 35.9 6.4 5.5 35.9 2.7 1 1 0 1 1 1 0 Sugar (and other) transporter DUF4381 PF14316.6 KND91016.1 - 0.56 10.4 3.2 0.3 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) GMC_oxred_N PF00732.19 KND91018.1 - 3.1e-25 89.1 1.1 1.1e-22 80.7 1.1 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND91018.1 - 1e-21 78.0 0.0 1.8e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GRDP-like PF07173.12 KND91019.1 - 8.5e-17 62.1 3.7 3.8e-14 53.5 0.1 3.1 3 1 0 3 3 3 2 Glycine-rich domain-containing protein-like zf-Sec23_Sec24 PF04810.15 KND91019.1 - 0.2 11.7 2.4 0.33 11.0 0.3 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Pyr_redox_2 PF07992.14 KND91020.1 - 2.9e-05 23.4 0.1 3.6e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND91020.1 - 0.00024 20.3 0.0 0.00027 20.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND91020.1 - 0.00078 19.6 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KND91020.1 - 0.0017 17.7 0.1 0.0021 17.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KND91020.1 - 0.0083 14.9 0.0 0.0099 14.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KND91020.1 - 0.019 14.0 0.1 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 KND91020.1 - 0.035 13.4 0.1 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND91020.1 - 0.04 13.2 0.1 0.052 12.8 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND91020.1 - 0.049 12.9 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KND91020.1 - 0.08 12.0 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Bac_luciferase PF00296.20 KND91022.1 - 6.3e-52 176.9 0.8 9.8e-52 176.3 0.8 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.12 KND91022.1 - 0.029 14.3 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Amidohydro_2 PF04909.14 KND91022.1 - 0.073 12.8 0.8 3.3 7.4 0.0 3.2 3 1 1 4 4 4 0 Amidohydrolase Asp PF00026.23 KND91023.1 - 4.5e-69 233.3 8.1 5.6e-69 233.0 8.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND91023.1 - 3.6e-16 59.9 3.0 7.6e-08 32.8 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND91023.1 - 3.7e-05 24.3 1.4 0.065 13.9 0.5 3.1 2 1 0 2 2 2 2 Aspartyl protease Hist_deacetyl PF00850.19 KND91024.1 - 1.8e-82 277.3 0.0 3.4e-82 276.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain RNA_pol_Rpc34 PF05158.12 KND91025.1 - 1.1e-98 330.7 0.0 1.4e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 KND91025.1 - 0.0046 17.6 0.0 0.041 14.5 0.0 2.4 3 0 0 3 3 3 1 Replication protein A C terminal HTH_36 PF13730.6 KND91025.1 - 0.0069 16.3 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain B-block_TFIIIC PF04182.12 KND91025.1 - 0.026 14.7 0.1 0.079 13.1 0.0 1.8 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Ribosomal_S25 PF03297.15 KND91025.1 - 0.099 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 S25 ribosomal protein Rrf2 PF02082.20 KND91025.1 - 0.2 12.0 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator MARVEL PF01284.23 KND91026.1 - 0.27 11.3 16.1 3 7.9 1.3 2.8 2 1 0 2 2 2 0 Membrane-associating domain TraL PF07178.11 KND91026.1 - 0.85 10.1 0.0 0.85 10.1 0.0 2.7 3 2 1 4 4 4 0 TraL protein Pkinase PF00069.25 KND91027.1 - 2.1e-70 237.1 0.0 4.2e-70 236.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91027.1 - 4.5e-33 114.6 0.0 1.9e-31 109.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND91027.1 - 0.0098 14.7 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KND91027.1 - 0.012 14.9 2.5 2.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 KND91027.1 - 0.014 15.0 0.5 0.029 13.9 0.5 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KND91027.1 - 0.03 14.2 0.1 0.26 11.2 0.0 2.3 1 1 2 3 3 3 0 Phosphotransferase enzyme family Pro_isomerase PF00160.21 KND91028.1 - 1.6e-40 139.0 0.2 3.5e-40 137.9 0.1 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 KND91029.1 - 6.6e-45 152.2 0.1 9.9e-45 151.6 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KND91029.1 - 0.00067 18.7 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain RSN1_7TM PF02714.15 KND91032.1 - 4.9e-71 239.3 21.1 1e-70 238.2 21.1 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND91032.1 - 1.2e-43 148.5 0.4 1.2e-43 148.5 0.4 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND91032.1 - 1.1e-25 90.8 0.1 2.5e-25 89.7 0.1 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KND91032.1 - 1.1e-24 86.4 0.1 3e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KND91032.1 - 0.052 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OAD_gamma PF04277.13 KND91032.1 - 3.6 8.3 6.2 37 5.0 4.4 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cupredoxin_1 PF13473.6 KND91033.1 - 0.00098 19.2 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 KND91033.1 - 0.0015 18.9 0.0 0.0041 17.5 0.0 1.7 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KND91033.1 - 0.2 11.7 2.8 0.34 10.9 0.4 2.4 2 1 0 2 2 2 0 Plastocyanin-like domain NUDIX PF00293.28 KND91035.1 - 2.7e-07 30.7 0.0 1.3e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 NUDIX domain Pro_dh PF01619.18 KND91036.1 - 4.7e-68 229.9 0.0 5.6e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 KND91037.1 - 0.00021 21.6 4.6 0.00021 21.6 4.6 1.9 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family NACHT PF05729.12 KND91038.1 - 2.9e-22 79.3 0.2 3.7e-22 79.0 0.2 1.1 1 0 0 1 1 1 1 NACHT domain HET-s_218-289 PF11558.8 KND91038.1 - 3.2e-05 23.8 0.7 7.3e-05 22.7 0.7 1.6 1 0 0 1 1 1 1 Het-s 218-289 HET-S PF17108.5 KND91038.1 - 3.6e-05 23.4 2.3 8.6e-05 22.2 2.3 1.7 1 0 0 1 1 1 1 N-terminal small S protein of HET, non-prionic AAA_22 PF13401.6 KND91038.1 - 0.0021 18.3 0.0 0.0042 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND91038.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND91038.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 KND91038.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase RNA_helicase PF00910.22 KND91038.1 - 0.026 14.9 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KND91038.1 - 0.032 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KND91038.1 - 0.076 13.4 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IDO PF01231.18 KND91040.1 - 5.5e-149 496.6 0.0 6.5e-149 496.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KND91040.1 - 0.00071 18.4 0.0 0.051 12.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) CbtB PF09489.10 KND91040.1 - 0.082 13.0 0.3 0.21 11.7 0.3 1.7 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Aminotran_5 PF00266.19 KND91041.1 - 1.7e-07 30.6 0.0 3.5e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Fungal_trans PF04082.18 KND91042.1 - 7.6e-09 35.0 0.0 1.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91042.1 - 1.9e-05 24.7 12.0 3.2e-05 23.9 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 KND91043.1 - 6.8e-115 383.5 0.3 1.1e-114 382.9 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND91043.1 - 1.3e-27 96.6 0.0 2.7e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 KND91043.1 - 0.022 15.0 3.0 0.058 13.6 3.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL14-like protein AAA_33 PF13671.6 KND91043.1 - 0.11 12.6 1.2 0.68 10.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain TRF PF08558.10 KND91043.1 - 0.12 11.9 1.0 0.34 10.5 0.0 2.2 3 0 0 3 3 3 0 Telomere repeat binding factor (TRF) Fungal_trans PF04082.18 KND91044.1 - 7.4e-09 35.0 0.0 2e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91044.1 - 3.5e-08 33.4 7.0 6e-08 32.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.10 KND91045.1 - 1.4e-53 181.3 0.0 1.6e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 ADH_zinc_N PF00107.26 KND91046.1 - 1.4e-06 28.3 0.2 5.7e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND91046.1 - 1.6e-05 25.9 0.0 0.00012 23.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND91046.1 - 0.0012 18.7 0.0 0.0051 16.7 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SRF-TF PF00319.18 KND91047.1 - 1.6e-22 78.7 0.3 2.4e-22 78.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) His_Phos_2 PF00328.22 KND91048.1 - 6e-35 121.3 0.0 7.9e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sugar_tr PF00083.24 KND91049.1 - 3.1e-124 415.3 20.8 3.6e-124 415.1 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91049.1 - 5.9e-21 74.8 33.9 3.2e-15 55.9 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fasciclin PF02469.22 KND91051.1 - 0.0043 17.3 0.0 0.0084 16.3 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain FAD_binding_2 PF00890.24 KND91052.1 - 1e-82 278.5 0.8 1.2e-82 278.2 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KND91052.1 - 1.2e-20 73.4 0.2 9e-20 70.6 0.0 2.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KND91052.1 - 2.2e-13 50.5 0.2 4.2e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KND91052.1 - 4.6e-09 36.1 0.7 1.7e-08 34.3 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND91052.1 - 5.8e-07 29.0 0.8 5.9e-06 25.7 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND91052.1 - 1.1e-06 28.8 3.1 1.7e-06 28.2 0.5 2.6 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND91052.1 - 4.3e-06 26.2 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND91052.1 - 0.00055 19.3 1.6 0.065 12.5 0.8 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KND91052.1 - 0.0015 17.9 3.3 0.0058 15.9 3.3 1.8 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 KND91052.1 - 0.0018 17.4 3.3 0.16 11.0 1.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 KND91052.1 - 0.0026 16.5 6.6 0.015 14.0 0.2 3.2 3 1 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 KND91052.1 - 0.0079 15.5 0.5 1.2 8.3 0.1 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KND91052.1 - 0.0099 16.4 4.9 3 8.5 0.1 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KND91052.1 - 0.047 13.0 0.3 0.089 12.1 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MBOAT PF03062.19 KND91053.1 - 2.8e-48 165.1 17.0 5.5e-48 164.1 17.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family T4SS_CagC PF16943.5 KND91053.1 - 0.024 14.8 0.3 0.054 13.7 0.3 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system Cortexin PF11057.8 KND91053.1 - 0.16 11.8 1.4 0.96 9.4 0.5 2.8 2 1 0 2 2 2 0 Cortexin of kidney DUF3419 PF11899.8 KND91055.1 - 7.4e-162 538.9 0.0 1e-161 538.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 KND91055.1 - 3.5e-09 36.7 0.0 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91055.1 - 6.6e-09 36.4 0.0 5e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND91055.1 - 1.8e-08 35.0 0.0 6e-06 26.9 0.0 3.6 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91055.1 - 1.9e-06 28.4 0.0 0.0009 19.8 0.0 3.6 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91055.1 - 4.5e-06 26.5 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND91055.1 - 2.8e-05 23.6 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KND91055.1 - 0.00059 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1656 PF07869.12 KND91057.1 - 0.043 13.8 1.6 0.08 13.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Cwf_Cwc_15 PF04889.12 KND91057.1 - 0.091 12.5 5.6 0.15 11.8 5.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KND91057.1 - 0.39 11.1 6.6 0.7 10.3 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KND91057.1 - 0.95 8.7 4.3 1.3 8.3 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 KND91057.1 - 1.6 6.7 6.5 2.2 6.3 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bromodomain PF00439.25 KND91058.1 - 3.3e-24 84.8 0.8 9e-24 83.4 0.7 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 KND91058.1 - 4.1e-07 30.2 0.0 7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND91058.1 - 2.9e-06 27.2 0.2 7.3e-06 25.9 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND91058.1 - 0.00075 19.9 0.3 0.0016 18.8 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND91058.1 - 0.099 13.3 0.0 2.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MSA-2c PF12238.8 KND91058.1 - 5.7 6.9 7.1 17 5.4 0.2 2.8 3 0 0 3 3 3 0 Merozoite surface antigen 2c Mannosidase_ig PF17786.1 KND91059.1 - 1.4e-13 51.3 0.7 3.5e-13 50.0 0.1 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KND91059.1 - 8.6e-13 48.9 0.0 1.9e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KND91059.1 - 3.1e-05 23.6 0.0 9.9e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KND91059.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KND91059.1 - 0.0034 16.5 0.3 0.0094 15.1 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_S8 PF00082.22 KND91060.1 - 1.3e-25 90.3 18.1 3e-25 89.1 17.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND91060.1 - 6.1e-17 62.1 0.0 1.3e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 ROS_MUCR PF05443.11 KND91060.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein GMC_oxred_N PF00732.19 KND91062.1 - 2e-32 112.7 0.0 9.8e-29 100.6 0.0 2.6 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KND91062.1 - 9.7e-31 107.2 0.3 1.6e-30 106.5 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KND91062.1 - 0.0071 16.6 0.2 0.019 15.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND91062.1 - 0.0089 15.3 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND91062.1 - 0.01 15.0 0.2 0.019 14.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KND91062.1 - 0.036 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KND91062.1 - 0.11 12.1 0.3 0.21 11.2 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FeS_assembly_P PF01883.19 KND91063.1 - 2.6e-07 30.7 0.3 2e-06 27.9 0.1 2.4 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein DHDPS PF00701.22 KND91064.1 - 5e-46 156.7 0.0 6.1e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 KND91064.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peptidase_M1_N PF17900.1 KND91065.1 - 0.00017 21.9 0.0 0.5 10.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 KND91065.1 - 0.0035 16.9 0.0 0.0087 15.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KND91065.1 - 0.012 15.9 0.0 1.1 9.6 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Vps4_C PF09336.10 KND91065.1 - 0.07 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain NMT_C PF02799.15 KND91066.1 - 3.3e-84 281.6 0.0 4.8e-84 281.1 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KND91066.1 - 1.2e-73 246.2 0.6 1.9e-71 239.1 0.0 2.2 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KND91066.1 - 4.1e-05 23.7 0.1 0.0062 16.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Cut8 PF08559.10 KND91066.1 - 0.0055 16.4 0.2 0.0092 15.6 0.2 1.3 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Sin3a_C PF16879.5 KND91067.1 - 2.5e-71 240.7 2.2 7.5e-71 239.2 0.4 2.5 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 KND91067.1 - 1.2e-42 143.8 4.2 8.3e-18 64.3 0.0 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KND91067.1 - 1.3e-40 137.4 0.3 5.6e-40 135.4 0.0 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Baculo_PP31 PF05311.11 KND91067.1 - 0.13 11.8 3.3 1.8 8.0 1.4 2.7 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) TSP_NTD PF17804.1 KND91067.1 - 0.47 10.7 8.2 0.21 11.8 0.1 3.3 4 0 0 4 4 4 0 Tail specific protease N-terminal domain Abhydrolase_6 PF12697.7 KND91069.1 - 8.4e-13 49.4 2.4 8.4e-13 49.4 2.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND91069.1 - 1e-11 44.6 0.9 2.4e-11 43.4 0.9 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND91069.1 - 3.4e-09 36.7 1.3 5e-09 36.2 0.9 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KND91069.1 - 0.00011 22.2 1.2 0.0002 21.3 1.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KND91069.1 - 0.0089 15.6 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Cutinase PF01083.22 KND91069.1 - 0.048 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.21 KND91069.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 KND91069.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Lipase PF00151.19 KND91069.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipase TLD PF07534.16 KND91070.1 - 7.3e-29 100.8 0.0 1.4e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 KND91070.1 - 2.4e-14 54.1 0.7 2.4e-14 54.1 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function VIT1 PF01988.19 KND91071.1 - 1.5e-62 211.3 4.8 1.8e-62 211.0 4.8 1.1 1 0 0 1 1 1 1 VIT family Mid2 PF04478.12 KND91071.1 - 0.01 15.7 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor ZZ PF00569.17 KND91072.1 - 5.1e-10 39.0 7.4 9.4e-10 38.2 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 KND91072.1 - 2.4e-07 31.1 9.1 0.0008 19.8 0.3 4.5 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 KND91072.1 - 6.9e-07 28.4 3.6 4.8e-05 22.6 0.2 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KND91072.1 - 0.00044 20.0 0.2 0.00044 20.0 0.2 4.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 KND91072.1 - 0.0085 15.9 5.0 0.3 11.0 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_4 PF12763.7 KND91072.1 - 0.019 14.9 0.1 0.077 12.9 0.0 2.1 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C1_2 PF03107.16 KND91072.1 - 0.11 12.9 10.4 0.2 12.0 10.4 1.4 1 0 0 1 1 1 0 C1 domain EF-hand_5 PF13202.6 KND91072.1 - 0.67 9.6 10.5 0.65 9.6 0.2 4.4 4 0 0 4 4 4 0 EF hand SpoIIIAH PF12685.7 KND91072.1 - 2.6 7.8 11.4 16 5.2 0.6 3.2 3 0 0 3 3 3 0 SpoIIIAH-like protein Abhydrolase_6 PF12697.7 KND91073.1 - 7.1e-09 36.6 15.5 1.1e-07 32.7 15.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KND91073.1 - 0.35 10.3 3.1 0.6 9.6 0.4 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Ada_Zn_binding PF02805.16 KND91074.1 - 1.1e-29 102.3 7.2 1.1e-29 102.3 7.2 1.8 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_18 PF12833.7 KND91074.1 - 7.2e-07 29.4 0.1 1.5e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_AraC PF00165.23 KND91074.1 - 3.8e-06 26.9 0.0 6.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family UPF0175 PF03683.13 KND91074.1 - 0.044 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) GTP_EFTU PF00009.27 KND91075.1 - 5.5e-46 156.6 0.0 8.7e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KND91075.1 - 3.4e-35 121.3 6.2 6.8e-35 120.3 6.2 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KND91075.1 - 5.9e-22 77.7 0.0 7.8e-15 54.7 0.0 2.9 2 0 0 2 2 2 2 Elongation factor G, domain IV EFG_C PF00679.24 KND91075.1 - 1e-18 67.1 0.0 2.8e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND91075.1 - 3.9e-09 36.8 0.0 9.8e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KND91075.1 - 1.1e-07 31.8 0.1 4.5e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KND91075.1 - 0.00029 20.9 0.1 0.00061 19.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PX PF00787.24 KND91076.1 - 2.5e-21 75.8 0.0 3.4e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.27 KND91077.1 - 9.7e-05 21.8 0.3 9.7e-05 21.8 0.3 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif PhoR PF11808.8 KND91078.1 - 0.028 14.8 1.2 0.031 14.7 0.1 1.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Gpr1_Fun34_YaaH PF01184.19 KND91079.1 - 2.3e-86 288.7 16.1 2.7e-86 288.5 16.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 KND91080.1 - 2.9e-28 98.8 52.3 7.1e-17 61.3 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND91080.1 - 2.3e-05 23.1 16.8 2.3e-05 23.1 16.8 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein Fungal_trans PF04082.18 KND91081.1 - 1.2e-17 63.8 1.3 2.4e-17 62.8 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91081.1 - 1.6e-06 28.1 9.9 1.6e-06 28.1 9.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.19 KND91083.1 - 2.4e-12 46.6 0.3 3.6e-11 42.8 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND91083.1 - 4.3e-05 23.6 2.2 0.0011 19.0 0.1 3.7 3 1 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.10 KND91083.1 - 0.0001 21.3 0.1 0.017 14.0 0.0 2.3 2 0 0 2 2 2 2 Cse1 Telomere_reg-2 PF10193.9 KND91083.1 - 0.035 14.6 0.3 1.8 9.1 0.1 3.0 3 0 0 3 3 3 0 Telomere length regulation protein UME PF08064.13 KND91083.1 - 0.048 13.6 1.7 0.25 11.3 0.2 2.8 3 0 0 3 3 3 0 UME (NUC010) domain RSN1_7TM PF02714.15 KND91083.1 - 1.6 8.0 3.9 2.3 7.5 0.1 2.7 3 0 0 3 3 3 0 Calcium-dependent channel, 7TM region, putative phosphate Zn_clus PF00172.18 KND91084.1 - 1.7e-08 34.4 5.8 3.1e-08 33.6 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91084.1 - 3e-07 29.8 0.2 5e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4604 PF15377.6 KND91084.1 - 0.094 13.1 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Spherulin4 PF12138.8 KND91085.1 - 8.8e-75 251.4 0.0 9.9e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.21 KND91086.1 - 1.5e-37 129.4 0.0 2.6e-36 125.3 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND91086.1 - 1.6e-34 119.8 0.0 5.3e-24 85.2 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND91086.1 - 1e-05 24.7 0.2 0.026 13.6 0.0 2.7 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KND91086.1 - 6e-05 22.3 0.1 0.00032 19.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KND91086.1 - 0.00013 21.3 0.0 0.00041 19.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 KND91086.1 - 0.0014 18.1 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND91086.1 - 0.015 15.2 0.5 4.3 7.2 0.2 2.3 2 0 0 2 2 2 0 KR domain Pyr_redox_2 PF07992.14 KND91086.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Na_H_Exchanger PF00999.21 KND91087.1 - 1.7e-55 188.4 42.7 2.6e-55 187.8 42.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UPF0228 PF05727.11 KND91088.1 - 0.067 13.0 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0228) NIF PF03031.18 KND91091.1 - 1.8e-29 102.5 0.2 1.4e-18 67.1 0.1 2.3 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase DotU PF09850.9 KND91091.1 - 0.0041 16.9 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Type VI secretion system protein DotU Vta1 PF04652.16 KND91092.1 - 1.7e-43 148.1 0.0 1.1e-42 145.4 0.0 2.1 2 1 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KND91092.1 - 2.3e-17 62.4 0.0 5.1e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Thioredoxin PF00085.20 KND91094.1 - 1.6e-30 105.1 0.0 1.1e-24 86.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KND91094.1 - 1.3e-07 32.0 0.0 0.0042 17.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KND91094.1 - 2.4e-05 23.8 0.0 0.00073 19.0 0.0 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KND91094.1 - 6.5e-05 22.9 7.2 0.01 15.7 0.0 3.5 3 0 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 KND91094.1 - 0.0002 21.6 0.0 13 6.2 0.0 4.0 3 2 1 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.21 KND91094.1 - 0.006 16.5 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 KND91094.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KND91094.1 - 0.15 12.1 0.2 6.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain CPSF100_C PF13299.6 KND91094.1 - 2.4 8.3 9.6 2.7 8.2 4.0 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RNase_PH PF01138.21 KND91095.1 - 2.6e-36 125.0 0.2 4.3e-36 124.3 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND91095.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 SAS4 PF15460.6 KND91096.1 - 3.5e-32 110.4 1.5 6.7e-32 109.5 0.1 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 SAPS PF04499.15 KND91096.1 - 0.54 9.0 7.0 1.5 7.5 6.1 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 KND91096.1 - 3.2 5.9 12.4 5.1 5.3 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Adaptin_binding PF10199.9 KND91096.1 - 9.1 6.9 15.1 11 6.7 12.3 2.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Arginosuc_synth PF00764.19 KND91097.1 - 2.7e-144 481.2 0.0 3.2e-144 481.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KND91097.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ubiquitin PF00240.23 KND91098.1 - 2e-19 69.1 0.0 3.1e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KND91098.1 - 7.6e-07 28.9 0.1 7.6e-07 28.9 0.1 2.7 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.8 KND91098.1 - 4.8e-05 23.1 0.0 8.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KND91098.1 - 0.0036 17.4 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KND91098.1 - 0.0079 16.7 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 KND91098.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 KND91098.1 - 0.052 13.5 22.6 0.063 13.2 4.4 4.0 3 1 1 4 4 4 0 STI1 domain TPPII_N PF12583.8 KND91098.1 - 0.055 14.1 0.1 0.055 14.1 0.1 2.7 4 0 0 4 4 4 0 Tripeptidyl peptidase II N terminal Ubiquitin_2 PF14560.6 KND91098.1 - 0.085 13.3 0.4 0.41 11.1 0.4 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KND91098.1 - 0.58 10.1 5.7 0.37 10.8 1.9 2.4 2 1 0 2 2 2 0 Spore germination GerD central core domain Rad4 PF03835.15 KND91099.1 - 1.8e-14 53.6 4.0 3.2e-14 52.8 4.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KND91099.1 - 4.2e-12 46.5 4.0 2.1e-11 44.2 2.8 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily FKBP_C PF00254.28 KND91100.1 - 1.7e-19 69.9 0.2 2.8e-19 69.2 0.2 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF5585 PF17823.1 KND91100.1 - 0.017 14.1 0.2 0.021 13.8 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Polysacc_deac_1 PF01522.21 KND91101.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase Glyco_hydro_114 PF03537.13 KND91102.1 - 2.9e-82 275.4 0.5 3.5e-82 275.2 0.5 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ETRAMP PF09716.10 KND91102.1 - 0.025 14.6 0.1 0.057 13.5 0.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OppC_N PF12911.7 KND91102.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMSR PF01625.21 KND91103.1 - 3.4e-60 202.7 0.2 4.2e-60 202.4 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase cNMPbd_u2 PF16643.5 KND91104.1 - 1.5e-37 129.4 14.6 3.4e-37 128.3 14.6 1.6 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 KND91104.1 - 4.7e-34 116.3 0.0 8.7e-19 67.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Bax1-I PF01027.20 KND91104.1 - 1e-32 113.7 7.4 1.5e-32 113.2 7.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 LRR_6 PF13516.6 KND91104.1 - 5.3e-08 32.3 7.2 0.045 13.8 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KND91104.1 - 2.3e-06 27.9 0.2 0.049 14.1 0.0 4.3 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KND91104.1 - 4.3e-06 26.5 1.1 8.9e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND91104.1 - 1.3e-05 24.9 0.4 1.3e-05 24.9 0.4 3.2 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 KND91104.1 - 0.0084 16.5 4.0 16 6.6 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 KND91104.1 - 0.023 14.5 0.1 4.8 7.0 0.0 3.2 2 1 0 2 2 2 0 Leucine rich repeat Zn_clus PF00172.18 KND91105.1 - 6.9e-09 35.7 8.8 1.3e-08 34.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91105.1 - 0.038 13.0 0.0 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Ribophorin_II PF05817.14 KND91106.1 - 4.1e-25 88.4 0.1 5.2e-25 88.1 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Abhydrolase_1 PF00561.20 KND91106.1 - 3.8e-15 56.2 0.0 8e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND91106.1 - 4.5e-14 53.6 0.6 1e-13 52.4 0.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND91106.1 - 5.6e-11 42.2 0.0 1.3e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 KND91106.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein TgMIC1 PF11476.8 KND91106.1 - 0.02 14.6 0.6 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF1100 PF06500.11 KND91106.1 - 0.03 13.1 0.0 0.045 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.12 KND91106.1 - 0.065 13.2 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Esterase_phd PF10503.9 KND91106.1 - 0.087 12.3 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase HIG_1_N PF04588.13 KND91107.1 - 1e-21 76.9 0.3 1.8e-21 76.1 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TPR_16 PF13432.6 KND91107.1 - 0.19 12.4 4.7 0.98 10.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2514 PF10721.9 KND91107.1 - 1.1 9.3 12.4 1.9 8.5 11.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) DUF3918 PF13056.6 KND91107.1 - 8.7 6.1 7.0 1.9 8.2 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3918) Egh16-like PF11327.8 KND91109.1 - 2.1e-54 184.7 10.9 3.4e-54 184.1 10.9 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor Collagen PF01391.18 KND91109.1 - 1.7e-06 27.7 67.7 4.2e-05 23.2 30.8 3.1 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 KND91111.1 - 2.6e-36 125.4 0.0 4.4e-36 124.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91111.1 - 1.1e-19 70.7 0.0 4.5e-19 68.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND91111.1 - 7.8e-05 22.1 0.0 0.0002 20.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like ABC1 PF03109.16 KND91111.1 - 0.0049 17.0 0.1 0.0093 16.1 0.1 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KND91111.1 - 0.024 14.6 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ctr PF04145.15 KND91112.1 - 1.9e-36 125.9 0.3 2.4e-36 125.6 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3810 PF12725.7 KND91112.1 - 0.36 10.1 1.7 0.57 9.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Abhydrolase_1 PF00561.20 KND91113.1 - 1.4e-16 60.9 0.1 8.8e-15 55.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KND91113.1 - 1.4e-13 50.8 0.0 3.3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Amino_oxidase PF01593.24 KND91114.1 - 2.9e-32 112.5 1.0 1.1e-24 87.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND91114.1 - 1.6e-08 34.7 0.9 4.4e-08 33.2 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND91114.1 - 2.2e-06 27.2 0.1 3.6e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND91114.1 - 2.6e-06 26.8 0.2 4.6e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KND91114.1 - 3.5e-06 26.0 1.0 4.8e-05 22.2 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 KND91114.1 - 4.1e-06 26.6 0.5 7.1e-05 22.5 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KND91114.1 - 6.6e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KND91114.1 - 1.4e-05 24.7 0.5 1.9e-05 24.2 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND91114.1 - 3.3e-05 23.3 0.1 5e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KND91114.1 - 6.5e-05 22.3 0.3 0.00058 19.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KND91114.1 - 0.00021 20.5 0.3 0.0012 18.1 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KND91114.1 - 0.00087 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KND91114.1 - 0.0055 17.2 0.1 0.02 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND91114.1 - 0.014 14.5 0.6 0.37 9.8 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KND91114.1 - 0.02 14.9 0.3 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND91114.1 - 0.18 10.9 0.1 11 5.1 0.1 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UPF0489 PF12640.7 KND91114.1 - 0.2 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Sugar_tr PF00083.24 KND91115.1 - 1.3e-46 159.5 17.4 1.6e-46 159.1 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91115.1 - 6.8e-18 64.7 24.2 1.1e-17 64.0 24.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Hemerythrin PF01814.23 KND91116.1 - 5.5e-08 33.5 3.2 8.5e-08 32.9 2.9 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain PALP PF00291.25 KND91117.1 - 7.8e-77 258.6 0.6 1e-76 258.2 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KND91117.1 - 4e-39 132.3 0.0 2.9e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Glyco_hydro_76 PF03663.14 KND91118.1 - 1.3e-24 87.5 0.9 1e-22 81.2 0.9 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 NPR2 PF06218.11 KND91119.1 - 9.4e-121 403.6 0.0 6.8e-100 334.9 0.0 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 KND91120.1 - 3.5e-55 187.4 0.0 2.5e-53 181.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KND91120.1 - 5.8e-47 158.4 0.0 9.2e-46 154.6 0.0 2.2 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain Maf PF02545.14 KND91121.1 - 8.1e-27 94.1 0.0 1.4e-18 67.3 0.0 2.1 1 1 1 2 2 2 2 Maf-like protein tRNA-synt_2b PF00587.25 KND91122.1 - 3.9e-34 118.2 0.1 3.2e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KND91122.1 - 9.3e-07 28.9 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain CybS PF05328.12 KND91123.1 - 4.1e-49 165.7 0.0 5.3e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit NIBRIN_BRCT_II PF16508.5 KND91124.1 - 1.9e-38 131.4 0.0 5.8e-38 129.9 0.0 1.9 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KND91124.1 - 1.8e-08 34.6 0.0 3.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KND91124.1 - 0.00029 20.7 0.1 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Yop-YscD_cpl PF16697.5 KND91124.1 - 0.045 14.1 0.0 0.74 10.2 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DIOX_N PF14226.6 KND91125.1 - 3.3e-23 82.7 0.1 5.8e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND91125.1 - 6.6e-14 52.2 0.0 2.9e-13 50.2 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Scytalone_dh PF02982.14 KND91126.1 - 2.5e-43 147.6 0.7 2.8e-43 147.5 0.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase adh_short_C2 PF13561.6 KND91127.1 - 7.9e-46 156.5 0.1 9.2e-46 156.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND91127.1 - 2.8e-36 124.8 0.0 3.6e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND91127.1 - 2.5e-05 24.2 0.7 3.5e-05 23.8 0.7 1.4 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KND91127.1 - 0.027 13.8 0.2 0.04 13.2 0.2 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF971 PF06155.12 KND91127.1 - 0.059 14.0 0.0 0.1 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF971) NAD_binding_10 PF13460.6 KND91127.1 - 0.078 12.9 0.5 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ketoacyl-synt PF00109.26 KND91128.1 - 2.4e-71 240.3 0.0 5.3e-71 239.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KND91128.1 - 6.2e-52 176.7 0.4 1.9e-48 165.3 0.0 2.4 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KND91128.1 - 4.8e-39 134.7 0.1 1.4e-38 133.2 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND91128.1 - 8.1e-34 116.2 0.7 3.6e-33 114.1 0.3 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KND91128.1 - 6.7e-11 42.4 0.2 1.9e-10 41.0 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KND91128.1 - 4.1e-10 39.4 0.0 7.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KND91128.1 - 2.8e-08 34.2 0.0 1.4e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KND91128.1 - 0.00029 20.3 0.1 0.00062 19.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain TSC22 PF01166.18 KND91128.1 - 0.15 12.4 0.0 13 6.2 0.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Pkinase PF00069.25 KND91129.1 - 1.1e-05 24.9 0.0 0.0072 15.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND91129.1 - 0.013 14.8 0.0 0.32 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein tyrosine kinase adh_short_C2 PF13561.6 KND91130.1 - 1.5e-55 188.3 0.8 2e-55 187.9 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND91130.1 - 8.1e-49 165.7 1.4 9.8e-49 165.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND91130.1 - 2.4e-11 43.9 0.9 3.3e-11 43.4 0.9 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND91130.1 - 0.0015 17.7 0.8 0.002 17.3 0.6 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KND91130.1 - 0.01 15.3 0.2 0.033 13.6 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KND91130.1 - 0.053 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KND91130.1 - 0.17 11.7 2.4 0.19 11.6 0.8 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B PF00753.27 KND91131.1 - 9.2e-15 55.2 1.8 5.6e-09 36.3 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KND91131.1 - 0.00012 21.7 0.1 0.00028 20.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KND91131.1 - 0.0035 17.3 1.9 0.056 13.4 0.2 2.8 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain NAD_binding_10 PF13460.6 KND91133.1 - 2.9e-19 69.7 0.0 3.8e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND91133.1 - 2.2e-07 30.7 0.1 4.8e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 KND91133.1 - 0.0046 16.1 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KND91133.1 - 0.0096 15.4 0.1 0.021 14.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 KND91133.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 KND91133.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KND91133.1 - 0.02 15.3 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KND91133.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family JAB PF01398.21 KND91134.1 - 3.3e-14 52.9 0.0 6.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KND91134.1 - 2.2e-11 44.1 0.5 5.4e-11 42.9 0.5 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Asp PF00026.23 KND91135.1 - 1.4e-30 106.9 0.0 2.8e-30 105.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.25 KND91136.1 - 8.2e-33 113.5 1.5 1e-32 113.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND91136.1 - 1.3e-30 106.7 2.2 1.5e-30 106.5 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND91136.1 - 2.9e-09 37.1 2.2 6.9e-09 35.9 2.3 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 KND91136.1 - 0.0024 17.0 0.1 0.0063 15.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KND91136.1 - 0.035 13.5 0.0 0.097 12.1 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND91136.1 - 0.062 13.2 2.2 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 NAD(P)H-binding Ras PF00071.22 KND91137.1 - 1.3e-42 145.2 0.0 2.5e-42 144.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KND91137.1 - 5e-30 104.2 0.0 8.7e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND91137.1 - 8.1e-11 41.7 0.0 4.7e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND91137.1 - 0.00023 21.2 0.0 0.00046 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KND91137.1 - 0.0024 17.6 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 KND91137.1 - 0.0029 17.0 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 KND91137.1 - 0.0045 17.5 0.3 0.065 13.7 0.3 2.2 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 KND91137.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND91137.1 - 0.03 14.2 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 KND91137.1 - 0.043 14.2 0.1 0.094 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 KND91137.1 - 0.054 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KND91137.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KND91137.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND91137.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Malic_M PF03949.15 KND91138.1 - 2.3e-84 282.7 0.0 3.1e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KND91138.1 - 2.6e-63 213.1 0.0 4.3e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF5427 PF10310.9 KND91139.1 - 6.7e-179 595.7 0.1 8.6e-179 595.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF4597 PF15366.6 KND91139.1 - 0.078 12.7 0.3 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) SARAF PF06682.12 KND91139.1 - 0.099 12.3 3.6 0.19 11.3 3.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PROL5-SMR PF15621.6 KND91140.1 - 0.14 12.7 0.9 0.94 10.0 0.1 2.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family CBP4 PF07960.11 KND91140.1 - 4 7.3 8.5 24 4.8 0.3 3.2 2 0 0 2 2 2 0 CBP4 Ribosomal_L14 PF00238.19 KND91141.1 - 4.2e-27 94.7 0.0 5.4e-21 74.9 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L14p/L23e Ssu72 PF04722.13 KND91142.1 - 1.1e-86 289.3 0.0 1.3e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein NYN_YacP PF05991.11 KND91142.1 - 0.06 13.3 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 YacP-like NYN domain GIT_SHD PF08518.11 KND91143.1 - 4.2e-23 80.6 5.1 1.1e-13 50.5 1.2 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT IR1-M PF12185.8 KND91143.1 - 0.13 12.2 0.3 0.4 10.7 0.3 1.8 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain FUSC PF04632.12 KND91143.1 - 0.24 9.9 11.5 0.43 9.1 11.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PSII_Pbs27 PF13326.6 KND91143.1 - 0.61 10.4 8.9 1.7 8.9 2.9 3.1 1 1 0 2 2 2 0 Photosystem II Pbs27 OmpH PF03938.14 KND91143.1 - 0.63 10.4 33.2 7.5 6.9 6.3 4.2 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) THP2 PF09432.10 KND91143.1 - 0.95 9.5 11.5 0.058 13.5 2.9 2.6 1 1 1 2 2 2 0 Tho complex subunit THP2 UPF0242 PF06785.11 KND91143.1 - 4 7.5 34.0 21 5.1 14.7 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sipho_Gp157 PF05565.11 KND91143.1 - 5.2 7.1 18.7 0.15 12.1 9.1 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1664 PF07889.12 KND91143.1 - 5.6 7.0 24.3 19 5.3 0.2 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 KND91143.1 - 5.6 6.5 35.3 4.6 6.7 12.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF3958 PF13125.6 KND91143.1 - 8.4 6.6 30.1 20 5.5 12.9 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) JmjC PF02373.22 KND91144.1 - 4.8e-19 68.9 0.0 9.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF4448 PF14610.6 KND91145.1 - 1.4e-21 77.2 0.0 1.7e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.8 KND91145.1 - 0.046 13.4 1.0 0.064 13.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) TFR_dimer PF04253.15 KND91146.1 - 1.8e-25 89.4 0.0 3.3e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KND91146.1 - 5.1e-20 72.0 0.0 8.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KND91146.1 - 3.6e-09 36.5 0.1 2.6e-08 33.7 0.1 2.3 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 KND91146.1 - 0.0053 16.3 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DUF2206 PF09971.9 KND91147.1 - 0.001 17.9 0.2 0.0018 17.1 0.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) DUF4131 PF13567.6 KND91147.1 - 0.067 12.8 0.1 0.067 12.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NAD_binding_1 PF00175.21 KND91149.1 - 6.4e-33 113.7 0.0 1.5e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KND91149.1 - 6.7e-21 74.5 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KND91149.1 - 1.7e-09 37.9 0.0 0.0001 22.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain SH3_1 PF00018.28 KND91150.1 - 6e-09 35.4 0.0 9.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND91150.1 - 1.4e-07 31.3 0.1 2.8e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND91150.1 - 5.4e-06 26.0 0.0 0.00014 21.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF3716 PF12511.8 KND91152.1 - 1.6e-08 34.4 2.5 3e-08 33.6 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Sugar_tr PF00083.24 KND91153.1 - 5.4e-113 378.2 16.4 6.1e-113 378.0 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91153.1 - 4.1e-23 81.9 28.6 1.5e-13 50.4 2.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Rif1_N PF12231.8 KND91154.1 - 1.7e-143 478.1 3.2 1.7e-143 478.1 3.2 1.5 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal LRR_4 PF12799.7 KND91155.1 - 1.9e-33 113.9 20.8 8.1e-08 32.4 2.2 6.0 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND91155.1 - 6e-30 102.8 75.1 7.5e-08 32.0 3.1 5.6 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 KND91155.1 - 2.3e-14 53.3 8.3 1.3e-06 28.0 1.3 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 KND91155.1 - 6.5e-07 28.9 14.9 0.087 12.9 0.3 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 KND91155.1 - 0.0013 18.9 19.5 13 6.8 0.1 7.8 8 0 0 8 8 8 3 Leucine Rich Repeat BTB PF00651.31 KND91156.1 - 6.6e-08 32.8 0.2 2.7e-07 30.8 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Abhydrolase_3 PF07859.13 KND91157.1 - 4.5e-05 23.4 0.0 8.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KND91157.1 - 0.0035 17.0 0.1 0.025 14.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND91157.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L18A PF01775.17 KND91158.1 - 2.7e-52 176.0 0.3 3.7e-52 175.5 0.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 KND91159.1 - 6.7e-10 39.4 0.0 2.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain Ric8 PF10165.9 KND91160.1 - 4.3e-133 444.7 0.1 5e-133 444.5 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Acetyltransf_3 PF13302.7 KND91161.1 - 4.5e-30 105.1 0.1 6.2e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND91161.1 - 0.00065 19.9 0.1 0.022 15.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family SesA PF17107.5 KND91162.1 - 0.00014 22.1 0.2 0.0006 20.0 0.2 2.1 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases HMG_box PF00505.19 KND91163.1 - 1.9e-06 28.2 0.4 1.9e-06 28.2 0.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND91163.1 - 0.0053 17.3 0.1 0.0053 17.3 0.1 2.3 3 0 0 3 3 3 1 HMG-box domain Het-C PF07217.11 KND91164.1 - 2.1e-238 792.5 0.0 2.7e-238 792.1 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Tti2 PF10521.9 KND91164.1 - 0.087 12.4 0.3 0.52 9.8 0.2 2.1 1 1 1 2 2 2 0 Tti2 family Ada3 PF10198.9 KND91165.1 - 1.5e-54 183.7 0.0 3.9e-54 182.4 0.0 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Amidohydro_1 PF01979.20 KND91166.1 - 5.4e-76 256.1 0.6 7.2e-76 255.7 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 KND91166.1 - 1.6e-53 180.2 1.9 2.8e-53 179.4 1.9 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 KND91166.1 - 2e-12 47.3 0.0 4.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 KND91166.1 - 5.4e-11 42.6 1.7 3e-08 33.6 0.1 2.3 1 1 1 2 2 2 2 Amidohydrolase family VWA_3 PF13768.6 KND91167.1 - 5.9e-23 81.5 0.0 1.1e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KND91167.1 - 4.6e-09 36.8 0.0 7.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KND91167.1 - 2e-06 28.4 0.0 3.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KND91167.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein RunxI PF08504.11 KND91167.1 - 0.078 13.7 0.1 0.078 13.7 0.1 2.7 2 1 1 3 3 3 0 Runx inhibition domain VIT PF08487.10 KND91168.1 - 2.3e-29 101.8 0.0 3.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Transglut_prok PF09017.10 KND91169.1 - 7.5 5.8 5.7 14 4.8 1.1 2.1 2 0 0 2 2 2 0 Microbial transglutaminase zf-RING_2 PF13639.6 KND91170.1 - 4.8e-10 39.6 7.7 1.3e-09 38.2 7.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND91170.1 - 1.6e-07 31.0 7.4 4e-07 29.8 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND91170.1 - 4.1e-06 26.6 7.3 8.4e-06 25.6 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND91170.1 - 1e-05 25.1 8.8 1e-05 25.1 8.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KND91170.1 - 2.2e-05 24.6 6.4 7.2e-05 23.0 5.8 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KND91170.1 - 0.00041 20.3 2.9 0.00041 20.3 2.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND91170.1 - 0.00064 19.6 7.2 0.0013 18.7 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KND91170.1 - 0.0081 16.2 3.7 0.025 14.6 3.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KND91170.1 - 0.039 13.6 6.4 0.13 11.9 6.4 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KND91170.1 - 0.057 13.7 0.6 0.15 12.4 0.6 1.7 1 0 0 1 1 1 0 RING-like domain PAP2 PF01569.21 KND91170.1 - 0.092 12.5 1.2 0.77 9.5 0.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily DUF3955 PF13127.6 KND91170.1 - 0.3 10.9 2.1 0.55 10.1 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) zf-C3HC4_3 PF13920.6 KND91170.1 - 0.46 10.4 9.2 1 9.3 9.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND91170.1 - 0.78 10.0 9.3 1.7 8.9 9.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KND91170.1 - 0.88 9.5 12.7 0.61 10.0 10.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 KND91170.1 - 7.7 6.5 8.0 19 5.2 8.0 1.7 1 0 0 1 1 1 0 PHD-finger IMS PF00817.20 KND91172.1 - 3.2e-43 147.3 0.1 7e-43 146.2 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KND91172.1 - 8.2e-15 55.5 0.5 2.3e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KND91172.1 - 0.018 15.3 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif FKBP_C PF00254.28 KND91173.1 - 2.4e-34 117.5 0.0 3.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box PF00646.33 KND91175.1 - 2.4e-06 27.3 0.2 1.5e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KND91175.1 - 0.00011 22.0 0.1 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like Raf1_N PF18578.1 KND91175.1 - 0.028 14.9 0.0 0.028 14.9 0.0 1.8 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain Hydin_ADK PF17213.3 KND91175.1 - 0.037 14.3 0.1 0.048 13.9 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Maf1 PF09174.10 KND91175.1 - 0.065 13.4 1.1 0.09 12.9 1.1 1.2 1 0 0 1 1 1 0 Maf1 regulator TFIIA PF03153.13 KND91175.1 - 0.12 12.3 5.4 0.15 12.0 5.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRANC PF09372.10 KND91175.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 PRANC domain DUF758 PF05527.11 KND91175.1 - 0.56 10.2 2.8 0.82 9.6 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF758) Spt20 PF12090.8 KND91175.1 - 0.71 9.4 9.7 1.1 8.9 9.7 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 KND91175.1 - 4.4 7.4 19.9 11 6.2 19.9 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_24 PF13578.6 KND91176.1 - 1e-07 32.9 0.0 2.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND91176.1 - 0.0031 18.2 0.0 0.011 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF3176 PF11374.8 KND91177.1 - 4.8e-08 33.2 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4611 PF15387.6 KND91177.1 - 0.0048 17.1 1.1 0.03 14.5 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 KND91177.1 - 0.074 13.4 0.1 0.074 13.4 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_18 PF00704.28 KND91178.1 - 1.6e-50 172.6 0.1 4.2e-50 171.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 KND91178.1 - 3e-27 94.9 0.5 1.2e-26 92.9 0.5 2.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.20 KND91178.1 - 5.8e-06 26.3 0.1 0.043 13.9 0.1 3.2 3 0 0 3 3 3 2 LysM domain DUF1776 PF08643.10 KND91179.1 - 2.5e-100 335.7 0.0 3.1e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF3328 PF11807.8 KND91180.1 - 7.2e-49 166.5 2.4 9.2e-49 166.2 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-RING_2 PF13639.6 KND91181.1 - 8.7e-12 45.2 6.6 1.4e-11 44.5 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND91181.1 - 5e-08 32.7 6.1 8e-08 32.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND91181.1 - 7.1e-08 32.2 3.8 1.2e-07 31.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND91181.1 - 8e-08 31.9 1.0 1.4e-07 31.2 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 KND91181.1 - 1.4e-06 28.5 8.0 5.8e-06 26.5 8.0 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KND91181.1 - 8.1e-06 25.7 3.6 1.3e-05 25.0 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND91181.1 - 0.003 17.5 0.9 0.003 17.5 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KND91181.1 - 0.0039 17.0 2.8 0.0064 16.3 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND91181.1 - 0.0051 16.8 5.2 0.017 15.2 5.2 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND91181.1 - 0.024 14.4 6.5 0.043 13.6 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain OAD_gamma PF04277.13 KND91181.1 - 0.17 12.5 0.0 0.17 12.5 0.0 3.9 3 2 0 3 3 2 0 Oxaloacetate decarboxylase, gamma chain Prok-RING_4 PF14447.6 KND91181.1 - 0.22 11.4 4.8 0.48 10.3 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KND91181.1 - 0.26 11.2 6.0 0.48 10.4 6.0 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KND91181.1 - 0.29 11.3 2.8 0.83 9.9 2.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KND91181.1 - 0.43 10.3 4.6 0.82 9.3 4.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KND91181.1 - 0.94 9.7 4.6 2 8.6 4.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 KND91181.1 - 3.7 7.7 5.7 7.7 6.7 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger DUF3328 PF11807.8 KND91184.1 - 8.2e-41 140.2 1.6 9.6e-41 140.0 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.27 KND91185.1 - 1.9e-44 151.5 0.0 6.5e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND91185.1 - 2.3e-28 99.6 25.5 4.9e-25 88.7 12.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KND91185.1 - 3.1e-08 33.3 0.9 0.0077 15.7 0.0 4.1 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND91185.1 - 2.3e-07 31.0 1.2 0.22 11.3 0.0 3.6 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KND91185.1 - 1.8e-05 25.0 0.2 0.18 12.0 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND91185.1 - 2.2e-05 24.9 0.0 0.32 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KND91185.1 - 5.9e-05 22.7 0.5 0.38 10.5 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA PF00004.29 KND91185.1 - 0.00012 22.5 0.4 1.1 9.6 0.0 3.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND91185.1 - 0.00016 21.5 0.0 0.0093 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KND91185.1 - 0.00048 20.7 0.2 0.31 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KND91185.1 - 0.00052 20.1 0.2 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 KND91185.1 - 0.0006 20.0 0.0 0.79 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KND91185.1 - 0.0018 17.9 0.1 2 7.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 KND91185.1 - 0.0021 18.0 0.1 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 KND91185.1 - 0.0029 18.2 0.2 1.2 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KND91185.1 - 0.0094 15.7 0.4 4.3 6.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 KND91185.1 - 0.011 15.2 0.0 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 KND91185.1 - 0.014 15.2 0.4 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 KND91185.1 - 0.019 14.9 0.4 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.9 KND91185.1 - 0.045 12.6 0.1 0.38 9.5 0.0 2.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class T2SSE PF00437.20 KND91185.1 - 0.052 12.6 0.1 0.68 8.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 KND91185.1 - 0.072 12.8 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KND91185.1 - 0.072 13.1 1.5 11 6.0 0.2 2.5 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 KND91185.1 - 0.1 11.9 0.1 2.4 7.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 KND91185.1 - 0.12 11.8 0.2 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein CLP1_P PF16575.5 KND91185.1 - 0.13 12.1 0.1 4.4 7.1 0.0 2.8 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PRK PF00485.18 KND91185.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Polyoma_lg_T_C PF06431.11 KND91185.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus RNA_helicase PF00910.22 KND91185.1 - 0.18 12.2 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 KND91185.1 - 0.2 10.9 0.1 4.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Septin SRP-alpha_N PF04086.13 KND91186.1 - 0.088 12.7 22.0 0.12 12.3 22.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TSGP1 PF07771.11 KND91186.1 - 9.1 6.5 15.7 0.46 10.6 0.8 2.3 2 0 0 2 2 2 0 Tick salivary peptide group 1 DUF1708 PF08101.11 KND91187.1 - 1.1e-171 571.8 0.0 1.5e-171 571.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RGS12_us1 PF16613.5 KND91187.1 - 0.47 10.8 4.4 0.3 11.4 0.5 2.8 3 0 0 3 3 3 0 Unstructured region of RGS12 RNA_pol_Rpb1_1 PF04997.12 KND91188.1 - 2.7e-106 355.5 0.0 4.5e-106 354.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KND91188.1 - 6.7e-101 337.2 0.0 1.1e-100 336.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KND91188.1 - 2e-76 255.8 0.0 3.9e-76 254.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KND91188.1 - 7.6e-59 198.8 0.0 1.3e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KND91188.1 - 1.2e-46 158.0 8.1 1.8e-45 154.2 9.4 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KND91188.1 - 1.1e-43 148.9 0.0 2.3e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KND91188.1 - 7.2e-37 125.6 0.2 1.7e-36 124.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-CCCH PF00642.24 KND91191.1 - 5.3e-17 61.3 33.3 1.5e-07 31.2 0.6 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND91191.1 - 4.2e-13 48.9 33.8 3e-05 23.9 2.9 5.4 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 KND91191.1 - 2.8e-06 28.0 24.6 0.015 16.0 0.8 5.2 1 1 4 5 5 5 4 Torus domain Methyltransf_23 PF13489.6 KND91191.1 - 3.6e-06 26.9 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH_4 PF18044.1 KND91191.1 - 0.0036 17.1 2.0 0.0036 17.1 2.0 5.4 5 0 0 5 5 5 4 CCCH-type zinc finger Methyltransf_12 PF08242.12 KND91191.1 - 0.085 13.6 0.1 0.54 11.0 0.0 2.4 3 1 0 3 3 3 0 Methyltransferase domain bZIP_Maf PF03131.17 KND91192.1 - 0.056 14.0 1.4 0.23 12.0 1.4 2.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Memo PF01875.17 KND91193.1 - 3.1e-69 233.1 0.0 3.6e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein SET PF00856.28 KND91194.1 - 2.9e-08 34.3 0.0 4.1e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 SET domain Tom37 PF10568.9 KND91195.1 - 3.3e-38 130.8 0.2 6.2e-38 129.9 0.2 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KND91195.1 - 1e-09 39.0 0.0 4.4e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KND91195.1 - 1.6e-06 27.8 0.0 4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1 PF00133.22 KND91197.1 - 8.5e-151 503.2 0.0 1.2e-150 502.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KND91197.1 - 1.1e-20 73.8 0.0 1.3e-12 47.2 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KND91197.1 - 2.8e-15 56.6 0.0 5e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF945 PF06097.11 KND91197.1 - 0.0036 16.5 0.1 0.083 12.0 0.0 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF945) tRNA-synt_1_2 PF13603.6 KND91197.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 KND91197.1 - 0.015 15.2 4.0 0.041 13.8 4.0 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Pescadillo_N PF06732.11 KND91198.1 - 1.2e-121 405.5 0.1 2.3e-121 404.5 0.1 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 KND91198.1 - 4.2e-06 27.1 0.0 2.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND91198.1 - 0.00091 19.6 0.0 0.0045 17.4 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Astro_capsid_p PF12226.8 KND91198.1 - 0.0092 15.2 9.7 0.022 13.9 9.7 1.6 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Ribosomal_L14e PF01929.17 KND91198.1 - 0.11 13.0 3.7 0.4 11.2 3.7 2.0 1 0 0 1 1 1 0 Ribosomal protein L14 PIG-U PF06728.13 KND91199.1 - 1.8e-121 405.8 22.8 2.1e-121 405.6 22.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 KND91199.1 - 0.52 10.0 7.3 1.2 8.8 7.3 1.5 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain zf-C2H2 PF00096.26 KND91200.1 - 0.0018 18.6 0.5 0.0036 17.7 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KND91200.1 - 0.046 13.5 0.6 0.086 12.6 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain RRN9 PF10680.9 KND91201.1 - 3.1e-14 53.0 1.1 5.3e-14 52.2 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor MFS_1 PF07690.16 KND91202.1 - 1.7e-49 168.6 60.6 7.8e-48 163.2 60.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND91202.1 - 5.7e-24 84.5 20.6 7.5e-24 84.1 19.0 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND91202.1 - 2.2e-13 49.9 12.1 2.2e-13 49.9 12.1 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 KND91202.1 - 5.1 5.3 23.3 0.014 13.7 2.1 3.7 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PRIMA1 PF16101.5 KND91202.1 - 5.6 7.0 8.7 0.31 11.1 3.1 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Kinesin PF00225.23 KND91203.1 - 6.1e-110 367.3 2.4 6.1e-110 367.3 2.4 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND91203.1 - 1.4e-25 89.9 0.2 1.4e-25 89.9 0.2 3.1 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 KND91203.1 - 9.3e-08 32.5 0.8 9.3e-08 32.5 0.8 5.3 4 1 0 5 5 5 1 Kinesin-associated microtubule-binding BSMAP PF12280.8 KND91203.1 - 0.64 10.2 2.7 1.4 9.1 0.3 2.5 2 0 0 2 2 2 0 Brain specific membrane anchored protein DUF1308 PF07000.11 KND91203.1 - 1.8 8.5 7.8 0.33 10.9 0.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1308) GrpB PF04229.14 KND91205.1 - 1e-36 126.6 0.0 1.3e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Sulfatase PF00884.23 KND91206.1 - 2.8e-58 197.8 0.0 3.5e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KND91206.1 - 2.2e-25 88.2 1.4 4.5e-25 87.2 0.4 2.2 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 KND91206.1 - 5.6e-10 39.3 0.2 8.1e-09 35.5 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KND91206.1 - 4e-05 22.4 0.0 5.8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 KND91206.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF4994 PF16385.5 KND91206.1 - 0.073 13.0 0.0 5.7 6.9 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF1501 PF07394.12 KND91206.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TPT PF03151.16 KND91207.1 - 5.6e-34 117.8 15.9 6.7e-34 117.6 15.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KND91207.1 - 1.5e-06 27.7 19.7 1.4e-05 24.5 19.7 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 KND91207.1 - 0.054 13.7 33.7 0.45 10.7 10.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family Smim3 PF17307.2 KND91207.1 - 0.27 10.7 1.8 0.43 10.1 0.4 2.0 2 0 0 2 2 2 0 Small integral membrane protein 3 PCI PF01399.27 KND91209.1 - 1.7e-07 31.7 0.0 3.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KND91209.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain BDV_P40 PF06407.11 KND91209.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Borna disease virus P40 protein RGS PF00615.19 KND91210.1 - 1.4e-10 41.5 0.0 5.3e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.19 KND91211.1 - 2.2e-40 136.7 0.5 2.9e-40 136.4 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.26 KND91212.1 - 6.8e-49 165.1 0.0 8.8e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND91212.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND91212.1 - 0.0032 17.8 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KND91212.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain Aldo_ket_red PF00248.21 KND91213.1 - 6.8e-33 114.1 0.1 2.9e-30 105.5 0.1 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Na_Ca_ex PF01699.24 KND91214.1 - 4.2e-36 124.2 44.0 2.3e-19 69.8 21.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3087 PF11286.8 KND91214.1 - 0.09 12.2 0.6 0.27 10.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF872 PF05915.12 KND91214.1 - 0.16 12.1 6.3 1.7 8.8 0.0 3.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF3140 PF11338.8 KND91214.1 - 0.71 10.3 3.4 7 7.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Dehydrin PF00257.19 KND91214.1 - 4.4 7.8 10.6 1.2 9.7 2.2 2.5 2 0 0 2 2 2 0 Dehydrin Pkinase PF00069.25 KND91215.1 - 1.4e-60 205.0 0.0 2.4e-60 204.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91215.1 - 4.9e-34 117.8 0.0 1.6e-28 99.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KND91215.1 - 5.5e-07 29.2 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KND91215.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND91215.1 - 0.025 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KND91215.1 - 0.055 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CLTH PF10607.9 KND91216.1 - 1.1e-15 57.9 0.1 2.8e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Sigma54_DBD PF04552.13 KND91216.1 - 0.062 13.0 0.3 0.089 12.5 0.3 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Matrilin_ccoil PF10393.9 KND91216.1 - 0.2 11.5 1.5 0.53 10.2 0.2 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin L31 PF09784.9 KND91216.1 - 0.48 10.9 1.4 0.77 10.2 0.1 2.0 2 2 1 3 3 3 0 Mitochondrial ribosomal protein L31 CENP-Q PF13094.6 KND91216.1 - 1.9 8.7 8.8 4.6 7.4 8.8 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CLTH PF10607.9 KND91217.1 - 3e-10 40.2 0.0 4.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KND91217.1 - 1.3e-09 37.9 1.3 2.4e-09 37.0 1.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KND91217.1 - 1.5e-05 24.7 2.4 2.4e-05 24.1 2.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND91217.1 - 1.7e-05 24.7 2.1 2.8e-05 24.0 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KND91217.1 - 1.8e-05 24.5 1.9 3.3e-05 23.6 1.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KND91217.1 - 3.1e-05 23.7 3.1 6e-05 22.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KND91217.1 - 4.2e-05 23.1 0.1 4.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KND91217.1 - 5.9e-05 23.3 2.4 9.9e-05 22.6 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND91217.1 - 6.9e-05 22.6 3.3 0.00013 21.7 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KND91217.1 - 0.0019 18.0 2.1 0.0031 17.3 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KND91217.1 - 0.0048 17.0 1.3 0.01 16.0 1.3 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING LmjF365940-deam PF14421.6 KND91217.1 - 0.031 13.9 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Pellino PF04710.14 KND91217.1 - 0.035 12.8 0.4 0.043 12.5 0.4 1.2 1 0 0 1 1 1 0 Pellino KRAB PF01352.27 KND91217.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 KRAB box zf-MIZ PF02891.20 KND91217.1 - 0.12 12.2 2.0 0.28 11.0 2.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Amidase PF01425.21 KND91218.1 - 4e-52 177.7 0.1 3.4e-51 174.6 0.1 1.9 1 1 0 1 1 1 1 Amidase GATA PF00320.27 KND91220.1 - 5.5e-16 57.9 5.4 9.9e-16 57.1 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KND91220.1 - 3.3e-13 49.7 0.0 8.1e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 KND91220.1 - 1.8e-06 28.0 0.0 3.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 KND91220.1 - 1.4e-05 25.3 0.1 3.8e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 KND91220.1 - 0.0008 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 KND91220.1 - 0.0033 17.6 0.1 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 KND91220.1 - 0.008 16.3 0.2 0.02 15.0 0.2 1.7 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KND91220.1 - 0.1 12.1 0.6 0.71 9.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 KND91220.1 - 4.9 7.2 6.2 0.66 9.9 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) AAA_23 PF13476.6 KND91221.1 - 2.6e-35 122.7 1.0 2.6e-35 122.7 1.0 7.2 2 2 2 5 5 4 1 AAA domain AAA_21 PF13304.6 KND91221.1 - 1.2e-09 38.4 8.5 0.00066 19.6 3.3 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KND91221.1 - 1.1e-06 28.6 9.3 1.1e-06 28.6 9.3 5.5 1 1 1 3 3 2 2 AAA ATPase domain SbcCD_C PF13558.6 KND91221.1 - 7.9e-06 26.0 1.9 2e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 KND91221.1 - 0.00088 16.9 27.7 0.00088 16.9 27.7 6.0 3 1 2 5 5 5 2 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KND91221.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 KND91221.1 - 0.0057 16.7 4.1 0.0057 16.7 4.1 8.6 6 3 1 8 8 8 2 Laminin Domain II Fer4_18 PF13746.6 KND91221.1 - 0.02 15.0 0.8 0.16 12.2 0.8 2.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_16 PF13191.6 KND91221.1 - 0.024 15.0 0.0 0.024 15.0 0.0 4.0 3 2 0 3 3 3 0 AAA ATPase domain COG2 PF06148.11 KND91221.1 - 0.024 14.7 0.8 0.024 14.7 0.8 8.3 4 4 3 8 8 8 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.27 KND91221.1 - 0.074 13.6 0.0 0.074 13.6 0.0 6.8 5 1 0 5 5 4 0 ABC transporter AAA_22 PF13401.6 KND91221.1 - 0.1 12.9 4.3 0.24 11.7 0.1 3.8 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KND91221.1 - 0.13 12.4 4.0 0.17 12.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain AAA_13 PF13166.6 KND91221.1 - 0.21 10.2 98.1 0.19 10.3 0.1 6.3 2 2 4 6 6 6 0 AAA domain NPV_P10 PF05531.12 KND91221.1 - 2.4 8.7 35.5 0.08 13.4 0.4 7.8 6 3 0 6 6 6 0 Nucleopolyhedrovirus P10 protein SMC_N PF02463.19 KND91221.1 - 5.9 6.3 64.6 1.2e+02 1.9 64.6 3.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain IKKbetaNEMObind PF12179.8 KND91221.1 - 9.9 6.3 8.2 33 4.6 0.7 4.4 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain PPP4R2 PF09184.11 KND91222.1 - 2e-08 34.2 0.0 2e-08 34.2 0.0 2.4 2 0 0 2 2 2 1 PPP4R2 SPRY PF00622.28 KND91223.1 - 0.00032 20.8 0.0 0.00073 19.6 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Ribosomal_L36 PF00444.18 KND91224.1 - 3.2e-21 75.2 11.4 4.4e-21 74.8 11.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 KND91224.1 - 0.19 12.2 5.0 0.43 11.1 5.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L35 Complex1_LYR PF05347.15 KND91225.1 - 3.5e-17 62.2 0.5 5.4e-17 61.6 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND91225.1 - 9e-07 29.6 0.0 1.7e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KND91225.1 - 0.006 17.2 1.0 0.05 14.2 0.3 2.0 1 1 1 2 2 2 1 Complex1_LYR-like ABC_tran PF00005.27 KND91227.1 - 1.4e-50 171.4 0.0 1.3e-29 103.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND91227.1 - 3.7e-37 128.5 20.7 1.8e-26 93.4 9.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KND91227.1 - 6.4e-09 35.6 0.2 0.00038 20.0 0.0 4.0 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KND91227.1 - 9.9e-05 22.8 0.1 0.19 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND91227.1 - 0.0007 19.5 0.4 0.42 10.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KND91227.1 - 0.00077 19.5 1.1 0.19 11.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KND91227.1 - 0.0011 19.3 0.5 3.4 7.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KND91227.1 - 0.0021 17.7 1.0 2.1 8.2 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.7 KND91227.1 - 0.0048 15.9 0.1 0.36 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_21 PF13304.6 KND91227.1 - 0.011 15.6 0.5 10 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KND91227.1 - 0.011 15.4 0.0 0.38 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KND91227.1 - 0.011 15.4 0.1 4.2 7.1 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein T2SSE PF00437.20 KND91227.1 - 0.015 14.4 0.1 0.6 9.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein CbiA PF01656.23 KND91227.1 - 0.025 14.7 0.7 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 KND91227.1 - 0.057 12.7 0.6 0.57 9.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 KND91227.1 - 0.07 13.2 4.2 0.77 9.8 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 KND91227.1 - 0.081 11.9 0.1 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KND91227.1 - 0.18 11.5 0.7 11 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KND91227.1 - 1.2 9.6 6.3 1.5 9.3 0.5 2.7 3 0 0 3 3 2 0 AAA domain WD40 PF00400.32 KND91228.1 - 2.4e-15 56.7 15.6 0.0035 18.1 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91228.1 - 9.4e-15 54.7 0.0 0.00022 21.5 0.0 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND91228.1 - 0.00016 21.6 0.1 0.036 13.9 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND91228.1 - 0.12 11.3 0.1 17 4.2 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KND91228.1 - 1.1 9.3 5.1 4.4 7.4 0.6 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat LigD_N PF13298.6 KND91229.1 - 1.1e-34 118.8 0.0 2.2e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Peroxin-13_N PF04088.13 KND91230.1 - 2.6e-49 167.2 0.0 3.9e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KND91230.1 - 3.8e-09 36.1 0.0 6.6e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND91230.1 - 2.8e-06 26.9 0.0 4.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND91230.1 - 5.3e-05 23.0 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Atg14 PF10186.9 KND91231.1 - 8.8e-69 232.0 0.0 1.1e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 KND91231.1 - 7.1 5.0 12.4 10 4.5 12.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.25 KND91232.1 - 6.5e-60 202.7 0.0 7.9e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91232.1 - 1.2e-14 54.3 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND91232.1 - 1.4e-06 28.4 0.1 6e-05 23.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KND91232.1 - 0.0085 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KND91232.1 - 0.044 12.6 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Sec66 PF09802.9 KND91233.1 - 0.12 12.0 3.1 0.19 11.3 3.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Scm3 PF10384.9 KND91234.1 - 1.2e-19 69.7 0.0 3.4e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.12 KND91235.1 - 5.6e-72 241.4 0.0 9.6e-72 240.7 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 KND91235.1 - 1.2e-35 122.9 14.0 1.7e-35 122.4 14.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C4H2 PF10146.9 KND91235.1 - 0.0001 22.7 0.2 0.0001 22.7 0.2 2.1 2 0 0 2 2 2 1 Zinc finger-containing protein KASH_CCD PF14662.6 KND91235.1 - 0.0011 18.8 9.1 0.0017 18.2 9.1 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TMF_TATA_bd PF12325.8 KND91235.1 - 0.0013 18.9 10.3 0.005 17.0 9.7 2.0 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 KND91235.1 - 0.057 11.4 4.5 0.078 10.9 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KND91235.1 - 0.082 11.5 2.9 0.11 11.0 2.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KND91235.1 - 0.095 12.8 10.2 0.15 12.1 10.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 KND91235.1 - 0.099 12.5 9.6 0.17 11.7 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MIS13 PF08202.11 KND91235.1 - 0.13 11.5 7.2 0.18 11.1 7.2 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Suppressor_APC PF11414.8 KND91235.1 - 0.15 12.1 8.6 4.4 7.4 0.1 2.9 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein PHM7_cyt PF14703.6 KND91235.1 - 0.25 11.6 3.6 0.42 10.8 3.6 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter E2F_CC-MB PF16421.5 KND91235.1 - 0.26 11.7 1.9 0.7 10.3 1.9 1.8 1 0 0 1 1 1 0 E2F transcription factor CC-MB domain YabA PF06156.13 KND91235.1 - 0.34 11.6 3.7 0.48 11.1 2.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA FUSC PF04632.12 KND91235.1 - 0.69 8.4 2.7 0.97 7.9 2.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAUS-augmin3 PF14932.6 KND91235.1 - 0.82 9.2 12.4 0.87 9.1 11.4 1.4 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 3 AAA_23 PF13476.6 KND91235.1 - 1 9.8 4.8 1.6 9.1 4.8 1.4 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.22 KND91235.1 - 1.4 9.1 11.7 2.8 8.2 11.7 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 KND91235.1 - 1.8 7.8 13.3 3.1 7.0 11.7 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.19 KND91235.1 - 7.4 6.3 20.5 13 5.5 20.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4337 PF14235.6 KND91235.1 - 7.5 6.6 10.0 13 5.9 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BRE1 PF08647.11 KND91235.1 - 7.5 6.7 15.8 4.1 7.5 11.5 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 KND91235.1 - 8.7 6.5 18.8 0.43 10.8 12.9 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Dus PF01207.17 KND91236.1 - 8.7e-38 130.1 0.0 2.7e-28 99.0 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 KND91236.1 - 0.082 13.0 11.0 0.33 11.1 1.9 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 KND91236.1 - 0.11 12.5 10.2 0.92 9.5 1.8 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KND91236.1 - 1.8 8.4 12.8 0.49 10.3 2.8 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger HIG_1_N PF04588.13 KND91237.1 - 8.9e-07 29.0 1.2 2.3e-06 27.7 1.2 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CDI PF02234.19 KND91238.1 - 0.083 13.1 0.7 0.27 11.4 0.7 2.0 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor TFIIF_alpha PF05793.12 KND91238.1 - 0.086 11.4 50.9 1.1 7.8 50.8 3.0 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAPPC-Trs85 PF12739.7 KND91239.1 - 6.4e-116 387.7 0.1 8e-115 384.1 0.0 2.0 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit adh_short_C2 PF13561.6 KND91240.1 - 3e-52 177.5 0.1 3.9e-52 177.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND91240.1 - 4.4e-46 156.8 0.1 5.8e-46 156.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND91240.1 - 2e-12 47.4 0.3 2.9e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND91240.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND91240.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pyr_redox_2 PF07992.14 KND91240.1 - 0.0022 17.3 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Aa_trans PF01490.18 KND91243.1 - 2.1e-78 263.9 23.8 2.4e-78 263.6 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC2_membrane PF01061.24 KND91245.1 - 2.9e-37 128.1 20.4 2.9e-37 128.1 20.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KND91245.1 - 6.9e-25 88.2 0.0 1.3e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KND91245.1 - 7.4e-06 26.0 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND91245.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KND91245.1 - 0.009 15.6 0.0 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND91245.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 KND91245.1 - 0.035 13.6 0.0 0.46 9.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KND91245.1 - 0.055 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KND91245.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KND91245.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KND91245.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND91245.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KND91245.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thioredoxin_12 PF18400.1 KND91245.1 - 0.2 11.5 1.3 0.35 10.7 1.3 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain PDR_CDR PF06422.12 KND91245.1 - 1.5 8.8 4.5 0.71 9.8 0.1 2.8 3 0 0 3 3 3 0 CDR ABC transporter EGF PF00008.27 KND91245.1 - 3.6 8.0 19.6 0.22 11.8 2.5 4.3 3 0 0 3 3 3 0 EGF-like domain But2 PF09792.9 KND91246.1 - 1.1e-54 184.6 0.7 1.3e-54 184.4 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.12 KND91247.1 - 3.1e-50 169.7 0.5 4.7e-50 169.1 0.5 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KND91247.1 - 2.8e-14 53.2 0.0 4.5e-10 39.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 KND91247.1 - 0.00093 19.3 0.3 0.42 10.6 0.1 3.2 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 KND91247.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KND91247.1 - 0.0026 17.3 0.1 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KND91247.1 - 0.014 14.9 0.1 0.37 10.3 0.1 2.7 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 KND91247.1 - 0.042 13.3 0.0 8.7 5.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Arginase PF00491.21 KND91248.1 - 6e-80 268.7 0.1 8.2e-80 268.3 0.1 1.2 1 0 0 1 1 1 1 Arginase family WD40 PF00400.32 KND91249.1 - 8.1e-28 96.1 4.7 1.4e-06 28.9 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91249.1 - 3.3e-14 52.9 0.0 1.1e-06 28.8 0.0 3.9 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND91249.1 - 0.038 13.9 1.0 1.7 8.5 0.1 2.8 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Raffinose_syn PF05691.12 KND91250.1 - 1.1e-57 195.4 3.9 1.5e-55 188.3 3.9 2.2 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 KND91250.1 - 2.1e-07 30.5 0.6 3.4e-07 29.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ocr PF08684.10 KND91250.1 - 0.0035 17.7 0.1 0.012 16.1 0.1 1.9 1 0 0 1 1 1 1 DNA mimic ocr Melibiase PF02065.18 KND91250.1 - 0.019 13.9 1.2 0.033 13.1 1.2 1.3 1 0 0 1 1 1 0 Melibiase IMPDH PF00478.25 KND91251.1 - 2e-126 421.6 1.9 2.5e-126 421.4 1.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KND91251.1 - 4.5e-12 46.2 0.0 1.7e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KND91251.1 - 4.7e-07 29.5 1.8 0.012 15.0 2.8 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 KND91251.1 - 1e-06 28.0 1.9 1.9e-05 23.9 0.5 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 KND91251.1 - 0.00096 18.5 0.7 0.13 11.6 0.2 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KND91251.1 - 0.0012 18.4 1.2 0.018 14.5 1.2 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein Acetyltransf_1 PF00583.25 KND91252.1 - 2.3e-13 50.4 0.0 3.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND91252.1 - 2.2e-09 37.3 0.0 3.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND91252.1 - 3.4e-07 30.6 0.0 5.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND91252.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KND91252.1 - 0.00097 19.8 0.0 0.0015 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KND91252.1 - 0.015 15.0 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 KND91252.1 - 0.025 13.6 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Acetyltransf_CG PF14542.6 KND91252.1 - 0.045 13.9 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Histidinol_dh PF00815.20 KND91253.1 - 2.4e-161 537.3 5.2 3.2e-161 536.9 5.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KND91253.1 - 1.1e-24 86.1 0.1 2.2e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KND91253.1 - 1.8e-13 50.7 0.0 4.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.15 KND91254.1 - 6e-42 142.6 0.0 8.3e-42 142.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_M16 PF00675.20 KND91255.1 - 1.6e-57 193.7 0.2 4.3e-57 192.3 0.3 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND91255.1 - 3.8e-37 128.1 0.0 8.9e-37 126.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain RbsD_FucU PF05025.13 KND91255.1 - 0.11 13.0 0.1 0.56 10.6 0.1 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family M16C_assoc PF08367.11 KND91255.1 - 0.12 11.5 0.2 0.23 10.5 0.2 1.5 1 1 0 1 1 1 0 Peptidase M16C associated Pyr_redox_2 PF07992.14 KND91256.1 - 1.6e-49 168.8 1.1 1.9e-49 168.5 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND91256.1 - 5.2e-19 68.6 0.1 6.1e-18 65.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND91256.1 - 1.8e-17 63.7 0.5 4.2e-15 56.1 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KND91256.1 - 2.5e-05 24.7 0.1 0.0048 17.3 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 KND91256.1 - 0.00037 19.8 0.3 0.0016 17.7 0.0 2.1 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KND91256.1 - 0.00044 19.5 0.3 0.77 8.8 0.0 3.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KND91256.1 - 0.00044 20.4 2.3 0.12 12.7 0.0 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KND91256.1 - 0.001 18.5 0.1 0.057 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 KND91256.1 - 0.002 17.8 2.6 0.54 9.8 0.0 3.5 2 2 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 KND91256.1 - 0.0027 16.8 1.6 1.3 8.0 0.1 3.9 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KND91256.1 - 0.011 14.8 2.7 0.74 8.8 0.1 2.8 1 1 1 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 KND91256.1 - 0.016 15.3 0.0 17 5.5 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KND91256.1 - 0.034 13.4 1.7 14 4.8 0.0 3.0 2 1 1 3 3 3 0 FAD binding domain Vps53_N PF04100.12 KND91257.1 - 4.9e-106 354.9 1.9 7.9e-106 354.2 1.9 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KND91257.1 - 1.6e-06 27.7 7.2 2.7e-06 26.9 7.2 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KND91257.1 - 0.00041 20.2 1.8 0.00062 19.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.13 KND91257.1 - 0.00061 18.5 6.2 0.0011 17.6 6.2 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Seryl_tRNA_N PF02403.22 KND91257.1 - 0.0088 16.3 4.0 0.012 15.8 0.6 3.0 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF3919 PF13057.6 KND91257.1 - 0.11 12.1 0.3 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) Spc7 PF08317.11 KND91257.1 - 0.15 10.9 8.4 0.085 11.7 6.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 KND91257.1 - 0.17 12.1 1.7 0.91 9.8 0.7 2.6 1 1 1 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 KND91257.1 - 0.18 11.8 3.9 0.13 12.3 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KND91257.1 - 0.8 10.0 9.7 0.23 11.8 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) CR6_interact PF10147.9 KND91258.1 - 0.0025 17.6 1.1 0.0044 16.8 1.1 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 EphA2_TM PF14575.6 KND91258.1 - 0.045 14.6 0.1 0.13 13.1 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.16 KND91258.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM154 PF15102.6 KND91258.1 - 0.077 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 TMEM154 protein family Miga PF10265.9 KND91258.1 - 0.091 11.7 6.4 0.098 11.6 4.3 1.8 1 1 1 2 2 2 0 Mitoguardin RCR PF12273.8 KND91258.1 - 0.59 10.8 9.1 1.5 9.5 3.7 3.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red GLTT PF01744.20 KND91259.1 - 0.32 10.8 2.9 0.35 10.7 0.6 2.3 2 0 0 2 2 2 0 GLTT repeat (6 copies) FMN_red PF03358.15 KND91260.1 - 5.3e-07 29.5 0.0 6.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KND91260.1 - 7.3e-06 25.8 0.0 8.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Tyrosinase PF00264.20 KND91261.1 - 5.8e-35 121.6 1.1 9.8e-35 120.8 1.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Sacchrp_dh_C PF16653.5 KND91262.1 - 6.1e-75 252.7 0.0 8.9e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Pro_isomerase PF00160.21 KND91262.1 - 2.3e-42 145.0 0.0 3.5e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sacchrp_dh_NADP PF03435.18 KND91262.1 - 3.3e-20 72.6 0.2 5.3e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KND91262.1 - 2.5e-07 30.8 0.3 1.1e-05 25.6 0.0 2.5 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KND91262.1 - 0.11 12.4 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Herpes_capsid PF06112.11 KND91262.1 - 0.95 9.5 5.0 2.2 8.3 5.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TEA PF01285.18 KND91263.1 - 9e-27 92.9 0.0 2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 KND91264.1 - 1.6e-75 248.9 0.5 5e-20 71.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND91264.1 - 6.8e-11 41.9 0.0 0.00037 20.3 0.0 5.0 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KND91264.1 - 4.3e-07 30.0 0.0 0.63 10.2 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif RRM_3 PF08777.11 KND91264.1 - 2.7e-06 27.3 0.0 0.41 10.7 0.0 4.7 5 0 0 5 5 5 2 RNA binding motif Limkain-b1 PF11608.8 KND91264.1 - 1.6e-05 24.9 0.1 6.6 6.9 0.0 6.0 6 1 0 6 6 6 1 Limkain b1 RRM_Rrp7 PF17799.1 KND91264.1 - 2.1e-05 24.4 0.1 9.4 6.0 0.0 4.5 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain Smg4_UPF3 PF03467.15 KND91264.1 - 0.00014 22.0 0.1 0.082 12.9 0.0 3.6 3 1 0 3 3 3 1 Smg-4/UPF3 family Nup35_RRM_2 PF14605.6 KND91264.1 - 0.033 14.2 0.0 5 7.2 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KND91264.1 - 0.18 11.4 0.0 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 KND91264.1 - 0.58 10.4 4.4 15 5.8 0.1 4.5 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Thg1C PF14413.6 KND91265.1 - 2.7e-52 176.0 0.3 3.8e-52 175.6 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 KND91265.1 - 1e-51 174.2 0.0 1.5e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Pet100 PF09803.9 KND91265.1 - 0.14 12.7 0.2 0.32 11.5 0.2 1.6 1 0 0 1 1 1 0 Pet100 WD40 PF00400.32 KND91266.1 - 1.2e-11 45.0 6.5 0.0018 19.1 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91266.1 - 6.6e-10 39.2 0.8 0.00055 20.2 0.0 4.3 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KND91266.1 - 2.7e-05 24.2 0.1 0.13 12.1 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 KND91266.1 - 0.048 12.7 0.2 8.7 5.3 0.2 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain ADH_zinc_N_2 PF13602.6 KND91267.1 - 3.5e-22 79.9 0.1 6.6e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND91267.1 - 9.6e-16 57.9 0.3 1.5e-15 57.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF726 PF05277.12 KND91268.1 - 2e-110 369.0 0.2 2.6e-110 368.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KND91268.1 - 0.0013 18.9 0.3 0.004 17.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain SUV3_C PF12513.8 KND91268.1 - 0.03 14.2 0.7 0.064 13.2 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal Cutinase PF01083.22 KND91268.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase PE-PPE PF08237.11 KND91268.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 KND91268.1 - 2.6 8.6 11.1 0.086 13.4 3.1 2.5 3 1 1 4 4 4 0 Alpha/beta hydrolase family Sel1 PF08238.12 KND91269.1 - 1.3e-37 127.3 29.7 2.9e-05 24.6 0.0 13.0 13 0 0 13 13 13 8 Sel1 repeat TPR_6 PF13174.6 KND91269.1 - 4.2e-06 27.0 8.8 0.29 11.9 0.5 6.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND91269.1 - 0.00011 22.0 9.9 1.1 9.4 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND91269.1 - 0.00012 22.2 4.2 18 6.0 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND91269.1 - 0.013 15.6 3.9 8.1 6.9 0.0 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND91269.1 - 0.69 10.5 10.9 2.2 8.8 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat UDG PF03167.19 KND91270.1 - 3.5e-24 85.5 0.1 6.7e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily PLAC8 PF04749.17 KND91271.1 - 6.5e-23 81.6 8.3 8.5e-23 81.2 8.3 1.2 1 0 0 1 1 1 1 PLAC8 family fn3 PF00041.21 KND91272.1 - 1.6e-09 37.9 0.2 5e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Fibronectin type III domain F-box-like PF12937.7 KND91274.1 - 2.8e-12 46.3 1.5 6.1e-12 45.2 1.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND91274.1 - 8.5e-11 41.5 2.2 2.2e-10 40.1 2.2 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KND91274.1 - 0.044 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 F-box Rhodanese PF00581.20 KND91275.1 - 6.6e-15 55.6 0.0 1.2e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain SWI-SNF_Ssr4 PF08549.10 KND91276.1 - 0.011 14.4 2.8 0.014 14.1 2.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) RCR PF12273.8 KND91278.1 - 3.9e-09 37.2 11.4 5.3e-09 36.8 11.4 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Pil1 PF13805.6 KND91279.1 - 2e-124 414.4 0.0 2.5e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 KND91279.1 - 0.24 10.8 2.9 0.12 11.8 0.6 1.6 2 0 0 2 2 2 0 FAM92 protein EZH2_N PF18601.1 KND91280.1 - 4.1e-36 123.2 2.6 1.3e-35 121.5 2.6 1.9 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 KND91280.1 - 5.2e-26 90.0 5.2 1.2e-25 88.9 5.2 1.6 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 KND91280.1 - 6.6e-17 62.4 1.7 2.5e-15 57.3 0.1 3.3 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 KND91280.1 - 7.4e-06 26.3 15.1 7.4e-06 26.3 15.1 3.5 2 1 2 4 4 4 1 CXC domain Glyoxalase PF00903.25 KND91282.1 - 0.0075 16.5 0.1 0.058 13.6 0.0 2.2 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Taeniidae_ag PF05596.11 KND91282.1 - 0.24 11.4 0.0 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Taeniidae antigen Suf PF05843.14 KND91283.1 - 2.8e-14 53.8 9.6 0.0068 16.4 0.0 6.5 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KND91283.1 - 2.4e-09 37.2 23.8 3.1 8.9 0.6 10.7 9 3 1 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 KND91283.1 - 4.2e-07 29.5 5.9 0.0001 21.6 0.3 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KND91283.1 - 5.6e-07 29.6 10.1 0.8 9.7 0.2 7.5 7 1 1 8 8 8 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KND91283.1 - 6.1e-06 26.1 4.5 0.013 15.6 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND91283.1 - 0.00012 22.3 9.4 9.8 6.6 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 KND91283.1 - 0.035 13.3 0.2 0.035 13.3 0.2 5.1 3 2 1 6 6 6 0 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 KND91283.1 - 0.062 13.8 7.7 20 5.8 0.0 5.9 7 1 0 8 8 8 0 Tetratricopeptide repeat HAT PF02184.16 KND91283.1 - 1.4 9.0 15.4 0.64 10.0 1.4 6.3 6 1 0 6 6 6 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 KND91283.1 - 7.6 6.9 19.6 28 5.2 0.1 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 KND91284.1 - 0.28 11.3 8.4 0.43 10.7 8.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 KND91285.1 - 5.8e-24 83.7 0.3 9.9e-11 41.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND91285.1 - 5.5e-05 23.0 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif ATP-synt_D PF01813.17 KND91286.1 - 9e-71 237.8 0.7 1.2e-70 237.4 0.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.6 KND91286.1 - 0.34 10.2 0.1 0.34 10.2 0.1 1.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding HSP70 PF00012.20 KND91289.1 - 2.5e-223 742.7 6.2 2.8e-223 742.5 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND91289.1 - 1.3e-15 57.1 0.4 1e-14 54.1 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KND91289.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MFS_1 PF07690.16 KND91291.1 - 8e-34 117.1 36.0 1.5e-26 93.2 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91291.1 - 2.5e-08 33.2 6.5 2.5e-08 33.2 6.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND91291.1 - 9.9e-07 27.6 0.2 1.9e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RPEL PF02755.15 KND91292.1 - 3.4e-20 71.0 2.9 3.1e-09 36.2 0.3 2.4 2 0 0 2 2 2 2 RPEL repeat AT_hook PF02178.19 KND91293.1 - 0.11 12.5 1.4 0.22 11.5 1.4 1.6 1 0 0 1 1 1 0 AT hook motif SWIRM-assoc_2 PF16496.5 KND91294.1 - 0.0004 19.4 0.4 0.0004 19.4 0.4 2.1 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal BRCT PF00533.26 KND91294.1 - 0.053 13.9 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Aldose_epim PF01263.20 KND91296.1 - 9e-42 143.4 0.0 1e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 KND91297.1 - 2.7e-198 658.9 0.0 3e-198 658.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Myosin_head PF00063.21 KND91298.1 - 8.1e-238 791.0 3.0 9.9e-238 790.7 3.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KND91298.1 - 6.9e-49 166.1 0.0 1.3e-48 165.1 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KND91298.1 - 6.6e-12 44.9 0.2 1.3e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND91298.1 - 8.3e-10 38.4 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND91298.1 - 5.2e-07 29.2 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 KND91298.1 - 0.0082 15.7 0.5 3.7 7.0 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain IQ PF00612.27 KND91298.1 - 0.014 15.1 10.3 0.17 11.7 2.4 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 KND91298.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND91298.1 - 0.073 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KND91298.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain SepF PF04472.12 KND91298.1 - 0.092 13.0 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 Cell division protein SepF Peptidase_C14 PF00656.22 KND91299.1 - 0.0075 16.3 0.2 0.37 10.7 0.0 2.5 2 1 0 2 2 2 1 Caspase domain SelP_N PF04592.14 KND91299.1 - 0.4 10.0 7.0 0.82 9.0 7.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_transf_90 PF05686.12 KND91300.1 - 0.00046 19.2 0.3 0.013 14.4 0.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 90 DUF373 PF04123.13 KND91300.1 - 1.1 8.6 3.8 4 6.8 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Amidase PF01425.21 KND91301.1 - 7.6e-93 311.9 0.0 1e-92 311.5 0.0 1.2 1 0 0 1 1 1 1 Amidase WLM PF08325.10 KND91302.1 - 2.2e-39 135.5 0.3 3.5e-39 134.9 0.3 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KND91302.1 - 3.7e-05 22.9 2.7 6.5e-05 22.2 2.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KND91302.1 - 0.0029 17.7 3.3 0.0029 17.7 3.3 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 DUF2201_N PF13203.6 KND91302.1 - 2 8.0 7.1 3.1 7.3 7.1 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain WLM PF08325.10 KND91303.1 - 7.1e-57 192.6 0.1 1e-56 192.0 0.1 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KND91303.1 - 4.2e-05 22.8 2.7 7.6e-05 21.9 2.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KND91303.1 - 0.0034 17.5 3.3 0.0034 17.5 3.3 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF45 DUF2201_N PF13203.6 KND91303.1 - 2 7.9 6.8 3.1 7.3 6.8 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF1713 PF08213.11 KND91304.1 - 3.2e-08 33.3 20.2 3.2e-08 33.3 20.2 1.9 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 KND91304.1 - 0.079 13.7 0.1 0.17 12.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial protein Pet20 GNAT_acetyltr_2 PF13718.6 KND91305.1 - 3.9e-97 324.1 0.0 8.8e-97 323.0 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KND91305.1 - 1.1e-91 306.8 0.0 2e-91 305.9 0.0 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KND91305.1 - 2.2e-64 216.6 0.1 1.5e-63 213.8 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KND91305.1 - 1.7e-32 111.2 0.0 4.2e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KND91305.1 - 8.3e-05 22.4 0.6 0.013 15.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KND91305.1 - 0.0011 19.3 0.0 0.063 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 KND91305.1 - 0.095 12.9 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Dak2 PF02734.17 KND91306.1 - 9.8e-32 110.2 0.1 1.1e-31 110.1 0.1 1.0 1 0 0 1 1 1 1 DAK2 domain ATPgrasp_N PF18130.1 KND91306.1 - 0.084 13.4 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain RIP PF00161.19 KND91306.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosome inactivating protein DHDPS PF00701.22 KND91307.1 - 4.1e-40 137.3 0.0 5.1e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HATPase_c PF02518.26 KND91308.1 - 2.1e-29 102.3 0.2 4.1e-29 101.4 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KND91308.1 - 6.5e-22 77.3 0.1 2.1e-21 75.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 KND91308.1 - 1.1e-18 67.5 0.1 3.9e-18 65.7 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 KND91308.1 - 5.3e-16 58.7 0.2 6.5e-15 55.2 0.3 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KND91308.1 - 8.4e-14 51.7 0.0 1.5e-06 28.4 0.0 3.9 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 KND91308.1 - 4e-10 39.7 0.1 0.0011 19.0 0.0 4.4 5 0 0 5 5 5 2 PAS fold PAS_4 PF08448.10 KND91308.1 - 7.9e-10 39.0 2.8 4.1e-05 23.8 0.0 5.0 4 2 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KND91308.1 - 1.8e-05 24.7 0.1 0.17 11.9 0.0 4.0 4 0 0 4 4 4 2 PAS domain HATPase_c_3 PF13589.6 KND91308.1 - 0.089 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_8 PF08022.12 KND91309.1 - 3.6e-22 78.5 0.0 7.7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KND91309.1 - 5.7e-22 78.5 0.0 8.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KND91309.1 - 2.3e-20 72.9 10.0 2.3e-20 72.9 10.0 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KND91309.1 - 0.1 13.0 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Mpv17_PMP22 PF04117.12 KND91311.1 - 1.2e-25 89.5 2.4 2.1e-25 88.7 2.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Iso_dh PF00180.20 KND91312.1 - 4.8e-97 325.2 0.0 7.5e-97 324.6 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_1_2 PF00155.21 KND91313.1 - 4.6e-29 101.7 0.0 5.5e-26 91.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KND91313.1 - 0.013 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Allinase Aminotran_5 PF00266.19 KND91313.1 - 0.035 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KND91313.1 - 0.063 11.8 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Syntaxin PF00804.25 KND91315.1 - 1.3e-20 73.9 11.9 1.3e-20 73.9 11.9 2.0 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 KND91315.1 - 5.6e-11 42.3 5.7 5.6e-11 42.3 5.7 3.5 3 1 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 KND91315.1 - 0.0012 19.2 4.2 0.0012 19.2 4.2 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Orf78 PF06024.12 KND91315.1 - 0.0018 18.5 1.6 0.0027 18.0 0.2 2.0 2 0 0 2 2 2 1 Orf78 (ac78) ODV-E18 PF10717.9 KND91315.1 - 0.0039 17.0 2.1 0.0046 16.8 0.3 2.0 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 Chordopox_A33R PF05966.12 KND91315.1 - 0.0053 16.0 1.0 0.039 13.2 0.3 2.1 2 0 0 2 2 2 1 Chordopoxvirus A33R protein Baculo_11_kDa PF06143.11 KND91315.1 - 0.02 14.4 0.5 0.073 12.7 0.5 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Allexi_40kDa PF05549.11 KND91315.1 - 0.024 14.1 2.9 0.053 13.0 0.1 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein O-ag_pol_Wzy PF14296.6 KND91315.1 - 0.042 12.5 0.1 0.058 12.0 0.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy TMCO5 PF14992.6 KND91315.1 - 0.047 13.3 9.3 1.4 8.5 9.3 2.3 1 1 0 1 1 1 0 TMCO5 family Mid2 PF04478.12 KND91315.1 - 0.055 13.3 2.4 0.11 12.4 2.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Mod_r PF07200.13 KND91315.1 - 0.11 12.6 11.0 0.58 10.3 1.0 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.12 KND91315.1 - 0.14 10.7 10.4 0.24 9.9 10.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sigma_reg_N PF13800.6 KND91315.1 - 0.37 11.1 2.2 0.41 11.0 1.0 1.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF4834 PF16118.5 KND91315.1 - 7.8 7.5 9.5 0.39 11.7 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Glyco_hydro_18 PF00704.28 KND91316.1 - 2.3e-63 214.8 0.0 2.7e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Epimerase PF01370.21 KND91318.1 - 8.4e-13 48.3 0.1 1.4e-05 24.7 0.1 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND91318.1 - 2.4e-07 30.8 0.4 8.7e-07 29.0 0.2 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KND91318.1 - 0.00025 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KND91318.1 - 0.00074 20.0 0.0 0.002 18.6 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KND91318.1 - 0.002 18.4 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KND91318.1 - 0.011 14.8 0.0 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KND91318.1 - 0.013 14.7 0.0 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KND91318.1 - 0.021 14.2 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF4859 PF16151.5 KND91318.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Fiji_64_capsid PF05880.11 KND91318.1 - 0.16 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein RCR PF12273.8 KND91319.1 - 0.34 11.6 8.5 0.17 12.6 1.4 3.3 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red PG_binding_1 PF01471.18 KND91321.1 - 0.00026 21.2 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Tropomyosin_1 PF12718.7 KND91321.1 - 0.0081 16.3 2.0 0.0081 16.3 2.0 2.0 1 1 1 2 2 2 1 Tropomyosin like DUF812 PF05667.11 KND91321.1 - 0.019 13.9 0.4 0.036 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 KND91321.1 - 0.021 13.5 0.8 0.031 12.9 0.8 1.1 1 0 0 1 1 1 0 AAA domain Jnk-SapK_ap_N PF09744.9 KND91321.1 - 0.025 14.8 3.6 0.049 13.8 3.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PspA_IM30 PF04012.12 KND91321.1 - 0.029 13.9 5.1 0.054 13.1 5.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family SlyX PF04102.12 KND91321.1 - 0.034 14.7 9.1 0.31 11.7 2.0 2.6 2 0 0 2 2 2 0 SlyX DUF3450 PF11932.8 KND91321.1 - 0.038 13.3 1.7 0.066 12.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sigma70_ner PF04546.13 KND91321.1 - 0.04 13.8 0.8 0.078 12.9 0.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region K-box PF01486.17 KND91321.1 - 0.041 14.0 1.3 0.15 12.3 0.8 2.2 1 1 1 2 2 2 0 K-box region FPP PF05911.11 KND91321.1 - 0.042 12.0 2.9 0.061 11.5 2.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 KND91321.1 - 0.082 12.9 2.9 0.17 11.9 2.3 1.8 1 1 1 2 2 2 0 Laminin Domain II DUF2203 PF09969.9 KND91321.1 - 0.11 13.3 1.8 0.3 11.8 1.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF5082 PF16888.5 KND91321.1 - 0.12 12.6 0.7 1.4 9.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 KND91321.1 - 0.14 11.0 6.8 0.14 11.0 4.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Kre28 PF17097.5 KND91321.1 - 0.14 11.0 2.3 0.21 10.5 2.3 1.1 1 0 0 1 1 1 0 Spindle pole body component DUF4795 PF16043.5 KND91321.1 - 0.15 11.6 1.1 0.29 10.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) XhlA PF10779.9 KND91321.1 - 0.17 12.1 1.5 0.82 9.9 0.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 KND91321.1 - 0.17 11.9 2.2 0.42 10.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HrpB7 PF09486.10 KND91321.1 - 0.27 11.6 9.0 0.25 11.7 1.2 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 KND91321.1 - 0.4 11.0 6.4 0.37 11.1 1.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CALCOCO1 PF07888.11 KND91321.1 - 0.4 9.5 7.6 0.66 8.8 7.6 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 KND91321.1 - 0.42 10.8 7.3 1 9.6 7.3 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 KND91321.1 - 0.8 10.0 6.7 2.8 8.2 6.6 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 CLZ PF16526.5 KND91321.1 - 0.8 10.1 3.7 12 6.4 0.2 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HMMR_N PF15905.5 KND91321.1 - 0.96 8.9 6.2 1.7 8.1 6.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Csm1_N PF18504.1 KND91321.1 - 1.4 9.3 5.7 3.5 8.0 1.8 2.5 1 1 0 2 2 2 0 Csm1 N-terminal domain ERM PF00769.19 KND91321.1 - 2 8.2 6.7 4.1 7.2 6.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pribosyltran PF00156.27 KND91322.1 - 5.8e-15 55.2 0.0 8.8e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KND91322.1 - 0.0083 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Cytochrom_B558a PF05038.13 KND91323.1 - 0.035 13.7 0.3 0.089 12.4 0.3 1.7 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Glyco_hydro_47 PF01532.20 KND91325.1 - 5e-110 368.5 0.0 6.5e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Zn_clus PF00172.18 KND91327.1 - 3.7e-06 26.9 10.2 3.7e-06 26.9 10.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91327.1 - 0.00091 18.3 0.1 0.0022 17.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-Tim10_DDP PF02953.15 KND91328.1 - 6.3e-20 70.6 2.4 7.6e-20 70.3 2.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Aldedh PF00171.22 KND91329.1 - 9.1e-139 462.9 0.3 1.1e-138 462.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KND91329.1 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) OmdA PF13376.6 KND91329.1 - 0.18 11.9 1.2 0.94 9.5 0.4 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ribosomal_S5 PF00333.20 KND91330.1 - 4.8e-26 90.5 1.6 1.3e-25 89.2 1.6 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KND91330.1 - 5.1e-22 77.1 0.0 5.1e-22 77.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Cyclin_N PF00134.23 KND91332.1 - 3.5e-35 120.5 0.2 5.7e-35 119.8 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KND91332.1 - 1.9e-09 37.7 0.2 8.7e-09 35.5 0.2 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.25 KND91334.1 - 7.9e-58 195.9 0.0 1.1e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91334.1 - 3.8e-27 95.2 0.0 5.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND91334.1 - 7.1e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND91334.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND91334.1 - 0.007 16.3 0.0 0.39 10.6 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cation_efflux PF01545.21 KND91335.1 - 8.7e-51 172.5 11.8 3.8e-50 170.4 11.8 1.8 1 1 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 KND91335.1 - 0.0069 15.6 0.6 0.0069 15.6 0.6 2.3 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component HHH PF00633.23 KND91336.1 - 0.0015 18.3 0.1 0.005 16.6 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Bap31 PF05529.12 KND91337.1 - 4.6e-48 162.5 10.2 6.3e-48 162.1 10.2 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KND91337.1 - 3.7e-11 42.9 13.9 5.9e-11 42.2 13.9 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain FlaC_arch PF05377.11 KND91337.1 - 0.082 13.3 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 KND91337.1 - 0.12 12.3 1.3 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF192 PF02643.15 KND91337.1 - 0.14 12.3 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 DivIC PF04977.15 KND91337.1 - 2.4 8.0 5.3 2.5 7.9 1.0 2.7 2 1 1 3 3 3 0 Septum formation initiator Methyltransf_16 PF10294.9 KND91339.1 - 1.5e-18 67.2 0.0 2.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KND91339.1 - 0.00025 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KND91339.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RNA_pol_N PF01194.17 KND91341.1 - 2.7e-29 101.2 1.0 3.5e-29 100.9 1.0 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KND91341.1 - 0.016 15.5 0.2 0.024 14.9 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DIOX_N PF14226.6 KND91342.1 - 1.2e-23 84.0 0.0 2.6e-22 79.8 0.0 2.5 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND91342.1 - 6.2e-12 45.9 0.0 1.8e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KND91342.1 - 4.9e-09 36.7 11.4 0.0007 20.4 0.9 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91342.1 - 0.014 15.7 0.2 1.1 9.5 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain zf-met2 PF12907.7 KND91343.1 - 6.4e-17 61.4 2.1 6.4e-17 61.4 2.1 1.6 2 0 0 2 2 2 1 Zinc-binding 4F5 PF04419.14 KND91343.1 - 2.1e-06 28.5 12.6 2.1e-06 28.5 12.6 1.5 2 0 0 2 2 2 1 4F5 protein family Lar_restr_allev PF14354.6 KND91343.1 - 0.018 15.4 1.0 0.022 15.1 1.0 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar HypA PF01155.19 KND91343.1 - 0.037 14.0 1.1 0.043 13.8 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BIR PF00653.21 KND91343.1 - 0.039 14.6 0.6 0.053 14.2 0.6 1.3 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-LSD1 PF06943.12 KND91343.1 - 0.04 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 LSD1 zinc finger zf-C2H2_12 PF18658.1 KND91343.1 - 0.048 13.2 0.2 0.065 12.8 0.2 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type NACHT PF05729.12 KND91344.1 - 1.4e-08 34.9 0.0 3.8e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KND91344.1 - 4.2e-06 27.2 0.4 3.5e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KND91344.1 - 0.0075 16.8 0.0 0.044 14.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND91344.1 - 0.013 15.9 0.1 0.096 13.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.23 KND91344.1 - 0.033 14.2 0.2 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytidylate_kin PF02224.18 KND91344.1 - 0.056 13.2 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA PF00004.29 KND91344.1 - 0.057 13.8 0.2 0.23 11.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND91344.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KND91344.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KND91344.1 - 0.35 10.0 5.2 0.24 10.6 1.0 2.1 1 1 0 2 2 2 0 KAP family P-loop domain ABC_membrane_2 PF06472.15 KND91345.1 - 2.8e-91 305.7 4.4 7.4e-91 304.3 0.3 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KND91345.1 - 1.9e-16 60.8 0.0 4.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KND91345.1 - 0.00097 19.0 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 KND91345.1 - 0.0042 16.5 0.1 0.0072 15.7 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KND91345.1 - 0.017 15.5 0.3 0.057 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KND91345.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KND91345.1 - 0.077 13.5 9.6 0.96 9.9 7.4 2.8 2 1 0 2 2 2 0 AAA domain DUF1772 PF08592.11 KND91347.1 - 0.21 11.9 2.0 0.42 10.9 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RNase_P_p30 PF01876.16 KND91349.1 - 2.6e-56 190.5 0.0 3.4e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 FAD_binding_3 PF01494.19 KND91350.1 - 4.7e-17 62.3 0.0 2.9e-16 59.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND91350.1 - 1.7e-05 25.0 0.1 4.2e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND91350.1 - 7.6e-05 22.1 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND91350.1 - 0.0014 18.3 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND91350.1 - 0.0043 15.8 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KND91350.1 - 0.0062 17.1 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KND91350.1 - 0.009 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KND91350.1 - 0.01 14.9 0.1 0.02 14.0 0.1 1.6 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KND91350.1 - 0.024 14.0 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 KND91350.1 - 0.057 12.5 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 KND91350.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KND91350.1 - 0.2 11.1 0.0 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Ribosomal_S8 PF00410.19 KND91351.1 - 4.1e-13 49.4 0.0 1.6e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Cornichon PF03311.14 KND91353.1 - 2.6e-33 115.0 20.0 1.6e-30 106.0 9.4 2.0 1 1 1 2 2 2 2 Cornichon protein Peptidase_M24 PF00557.24 KND91354.1 - 1.2e-39 136.2 0.1 1.6e-39 135.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KND91354.1 - 1.5e-20 73.2 6.2 1.5e-20 73.2 6.2 2.4 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KND91354.1 - 0.001 19.1 4.0 0.001 19.1 4.0 3.7 4 0 0 4 4 4 1 MYND finger Prefoldin_3 PF13758.6 KND91355.1 - 6.9e-30 103.0 0.8 6.9e-30 103.0 0.8 1.9 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 KND91355.1 - 5.8e-25 87.9 0.4 5.8e-25 87.9 0.4 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3835) KASH_CCD PF14662.6 KND91355.1 - 0.0035 17.2 2.0 0.011 15.6 2.0 1.8 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ABC_tran_CTD PF16326.5 KND91355.1 - 0.019 15.2 0.6 0.019 15.2 0.6 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain T3SS_needle_E PF08988.10 KND91355.1 - 0.038 14.1 0.6 9.1 6.5 0.2 3.5 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle MIP-T3_C PF17749.1 KND91355.1 - 0.096 12.7 7.9 0.058 13.4 0.9 2.8 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region FAA_hydro_N_2 PF18288.1 KND91355.1 - 0.26 11.7 1.9 0.6 10.6 0.3 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Prefoldin_2 PF01920.20 KND91355.1 - 0.54 10.2 7.8 0.39 10.7 0.2 3.3 3 0 0 3 3 3 0 Prefoldin subunit HR1 PF02185.16 KND91355.1 - 0.82 9.8 3.8 12 6.1 3.8 2.5 1 1 0 1 1 1 0 Hr1 repeat Prefoldin PF02996.17 KND91355.1 - 3.2 7.7 5.3 1 9.3 0.1 2.5 3 0 0 3 3 3 0 Prefoldin subunit Mur_ligase_M PF08245.12 KND91356.1 - 0.0012 18.8 0.0 0.0085 16.1 0.0 2.1 1 1 0 1 1 1 1 Mur ligase middle domain GPHH PF16905.5 KND91356.1 - 0.027 14.3 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Mur_ligase_C PF02875.21 KND91356.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Ribosomal_S17_N PF16205.5 KND91357.1 - 3.6e-33 113.8 0.2 5.8e-33 113.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KND91357.1 - 4.3e-26 90.8 0.2 7.9e-26 90.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF1719 PF08224.11 KND91358.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) DUF3128 PF11326.8 KND91358.1 - 1.4 9.3 11.0 7.2e+02 0.6 11.0 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Syja_N PF02383.18 KND91359.1 - 2.1e-88 296.7 0.1 2.7e-88 296.4 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Mitofilin PF09731.9 KND91361.1 - 1.2e-145 486.8 22.1 6.4e-124 415.1 17.4 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Mur_ligase_C PF02875.21 KND91361.1 - 0.0018 18.5 0.0 0.0085 16.3 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF3829 PF12889.7 KND91361.1 - 0.023 14.2 1.0 0.048 13.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) 4HB_MCP_1 PF12729.7 KND91361.1 - 0.55 9.8 9.2 1.5 8.3 8.0 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4449 PF14613.6 KND91361.1 - 0.78 9.8 5.8 2.1 8.4 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Csm1_N PF18504.1 KND91361.1 - 3.3 8.1 12.3 8.2 6.9 5.9 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Ras PF00071.22 KND91362.1 - 6.4e-55 185.2 0.1 8.1e-55 184.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND91362.1 - 7.2e-34 116.6 0.1 1.3e-33 115.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND91362.1 - 5.2e-12 45.6 0.0 6.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND91362.1 - 6.3e-06 25.9 0.0 9.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KND91362.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND91362.1 - 0.00022 20.7 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KND91362.1 - 0.0012 18.8 0.2 0.32 10.9 0.0 2.4 1 1 2 3 3 3 2 RsgA GTPase TniB PF05621.11 KND91362.1 - 0.15 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein Spc7_N PF15402.6 KND91364.1 - 2.1e-203 678.3 81.1 4.9e-202 673.8 81.1 2.1 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KND91364.1 - 1.1e-129 431.8 6.2 1.1e-129 431.8 6.2 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KND91364.1 - 2e-22 79.1 0.5 3.7e-22 78.2 0.5 1.5 1 0 0 1 1 1 1 Spc7_C2 Baculo_PEP_C PF04513.12 KND91364.1 - 0.0034 17.4 0.2 0.0092 16.0 0.2 1.7 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Bromo_MP PF01573.16 KND91364.1 - 0.068 12.5 0.2 1.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Bromovirus movement protein BLOC1_2 PF10046.9 KND91364.1 - 0.079 13.3 3.0 0.28 11.5 3.0 2.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 KND91364.1 - 0.98 9.7 5.9 2.2 8.6 0.3 3.6 2 2 0 3 3 3 0 Uncharacterized conserved protein DUF2312 PF10073.9 KND91364.1 - 9.2 6.0 10.1 1 9.0 2.2 3.4 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) GFA PF04828.14 KND91365.1 - 3e-16 59.5 1.9 4.8e-16 58.9 1.9 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_15 PF17032.5 KND91366.1 - 2.5e-05 24.9 0.9 3.7e-05 24.4 0.9 1.2 1 0 0 1 1 1 1 zinc-ribbon family PriA_CRR PF18319.1 KND91366.1 - 0.13 12.3 10.3 1.5 8.9 0.1 2.5 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Glyco_transf_28 PF03033.20 KND91367.1 - 2e-19 70.0 0.8 2.5e-11 43.8 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 KND91367.1 - 4.5e-06 26.9 0.0 2e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UDPGT PF00201.18 KND91367.1 - 0.0001 21.2 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KND91367.1 - 0.0021 18.0 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 KND91367.1 - 0.027 14.4 41.5 0.38 10.8 2.0 6.6 6 0 0 6 6 6 0 Ubiquitin interaction motif TH1 PF04858.13 KND91367.1 - 0.16 10.6 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 TH1 protein Sec61_beta PF03911.16 KND91368.1 - 9.5e-19 67.2 1.9 1.4e-18 66.6 1.9 1.3 1 0 0 1 1 1 1 Sec61beta family NIF PF03031.18 KND91369.1 - 1.5e-54 184.0 0.1 2e-54 183.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DHHC PF01529.20 KND91370.1 - 8.1e-29 100.4 2.6 8.1e-29 100.4 2.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 KND91370.1 - 0.07 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily Ribosomal_L40e PF01020.17 KND91370.1 - 0.18 11.7 6.8 0.33 10.9 6.8 1.3 1 0 0 1 1 1 0 Ribosomal L40e family FYVE PF01363.21 KND91370.1 - 0.21 11.8 7.4 0.42 10.8 7.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger Cwf_Cwc_15 PF04889.12 KND91370.1 - 2 8.1 11.1 2.8 7.6 11.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zinc_ribbon_2 PF13240.6 KND91370.1 - 2.7 7.8 5.4 5.4 6.9 5.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 KND91370.1 - 3 7.9 11.0 4.9 7.2 11.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.7 KND91372.1 - 0.00013 21.8 2.1 0.0002 21.2 0.4 2.4 2 0 0 2 2 2 1 F-box-like PRANC PF09372.10 KND91372.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 PRANC domain zf-P11 PF03854.14 KND91372.1 - 0.59 9.8 4.8 0.34 10.6 0.8 2.5 2 0 0 2 2 2 0 P-11 zinc finger UPF0183 PF03676.14 KND91373.1 - 1.1e-60 206.0 0.0 1.3e-38 133.3 0.0 3.1 2 1 1 3 3 3 3 Uncharacterised protein family (UPF0183) Rad60-SLD_2 PF13881.6 KND91373.1 - 0.072 13.2 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like FAD-oxidase_C PF02913.19 KND91374.1 - 9e-62 208.9 1.4 1e-61 208.7 0.1 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KND91374.1 - 8.2e-35 119.6 0.0 1.6e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.6 KND91375.1 - 4.4e-24 84.5 0.6 4.4e-24 84.5 0.6 2.6 3 0 0 3 3 3 1 Clr5 domain Herpes_IE68 PF02479.16 KND91375.1 - 0.001 18.7 0.7 0.0033 17.0 0.3 1.8 1 1 1 2 2 2 1 Herpesvirus immediate early protein ECH_1 PF00378.20 KND91376.1 - 1.4e-47 162.1 0.0 1.8e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND91376.1 - 7.4e-22 78.3 0.0 8.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1682 PF07946.14 KND91377.1 - 7.1 5.7 11.3 10 5.2 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glyco_tranf_2_3 PF13641.6 KND91378.1 - 6e-25 88.5 0.1 8.6e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KND91378.1 - 1.1e-06 28.5 0.0 3e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KND91378.1 - 1.4e-06 27.9 0.0 3.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF420 PF04238.12 KND91378.1 - 0.0062 16.8 1.4 0.015 15.6 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF420) GWT1 PF06423.12 KND91380.1 - 1.5e-42 145.3 2.2 1.5e-42 145.3 2.2 2.3 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 KND91380.1 - 0.0093 16.4 0.0 0.0093 16.4 0.0 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4818) tRNA-synt_2c PF01411.19 KND91382.1 - 4.7e-213 708.7 0.1 4.7e-213 708.7 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KND91382.1 - 1.1e-17 63.9 0.3 3.4e-17 62.3 0.3 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KND91382.1 - 2.5e-08 34.4 1.5 2.5e-08 34.4 1.5 3.1 3 1 0 3 3 3 1 DHHA1 domain Methyltransf_28 PF02636.17 KND91383.1 - 8.4e-40 137.0 0.0 1.3e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KND91383.1 - 0.0024 17.7 0.0 0.0097 15.8 0.0 1.9 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PALP PF00291.25 KND91384.1 - 2.4e-63 214.3 4.9 2.8e-63 214.1 4.9 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.14 KND91385.1 - 4e-27 94.9 0.2 1.1e-26 93.5 0.2 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain XPG_I PF00867.18 KND91385.1 - 3.8e-20 72.0 0.1 1e-19 70.6 0.1 1.8 1 0 0 1 1 1 1 XPG I-region TFIIS_C PF01096.18 KND91385.1 - 7.5e-18 64.1 7.2 1.5e-17 63.2 7.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KND91385.1 - 1.4e-09 37.8 0.5 4.1e-09 36.3 0.5 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain 5_3_exonuc PF01367.20 KND91385.1 - 0.017 15.7 0.0 0.078 13.6 0.0 2.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH PF00633.23 KND91385.1 - 0.14 12.1 0.1 0.48 10.4 0.1 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif XPG_N PF00752.17 KND91386.1 - 1.8e-33 115.0 0.0 4.2e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain UIM PF02809.20 KND91386.1 - 0.013 15.3 0.4 0.013 15.3 0.4 3.9 4 0 0 4 4 4 0 Ubiquitin interaction motif CAF1A PF12253.8 KND91386.1 - 0.075 13.2 0.3 0.075 13.2 0.3 4.0 5 0 0 5 5 5 0 Chromatin assembly factor 1 subunit A LSM PF01423.22 KND91387.1 - 4.1e-11 42.4 0.0 5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND91387.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF775 PF05603.12 KND91388.1 - 2e-58 197.2 0.0 2.7e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 KND91389.1 - 1.8e-13 50.5 0.0 2.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KND91389.1 - 1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain ThiF PF00899.21 KND91390.1 - 3.9e-16 59.2 0.0 7.6e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 ThiF family ThiF PF00899.21 KND91391.1 - 3.9e-16 59.2 0.0 7.6e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 ThiF family GDA1_CD39 PF01150.17 KND91392.1 - 3.8e-104 348.7 0.0 5.4e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family LPG_synthase_TM PF03706.13 KND91392.1 - 0.1 12.1 0.7 0.17 11.4 0.7 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region KA1 PF02149.19 KND91392.1 - 0.18 11.7 0.2 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 Kinase associated domain 1 TT_ORF1 PF02956.14 KND91392.1 - 0.35 9.5 0.5 0.53 8.9 0.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 adh_short PF00106.25 KND91393.1 - 1.9e-51 174.3 0.0 2.5e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND91393.1 - 1.2e-35 123.2 0.0 1.3e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND91393.1 - 2.2e-12 47.3 0.0 3.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KND91393.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 KND91394.1 - 4.3e-34 118.0 45.3 2.5e-33 115.5 45.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91394.1 - 5.7e-12 45.2 13.1 5.7e-12 45.2 13.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter XPG_I_2 PF12813.7 KND91395.1 - 1.8e-50 171.7 0.0 2.7e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing Pribosyltran_N PF13793.6 KND91396.1 - 2.8e-38 130.4 0.0 1.6e-35 121.6 0.0 3.1 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KND91396.1 - 3.3e-33 115.3 0.0 4e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KND91396.1 - 2.5e-08 33.6 0.0 0.00012 21.6 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Bud13 PF09736.9 KND91397.1 - 4.3e-47 160.1 8.9 4.3e-47 160.1 8.9 2.7 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex PAP_assoc PF03828.19 KND91398.1 - 6.7e-15 55.0 0.0 1.2e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KND91398.1 - 0.0029 17.9 0.0 0.0073 16.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain CDC45 PF02724.14 KND91398.1 - 0.83 7.9 9.4 1.5 7.0 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 KND91398.1 - 6.3 5.2 11.7 9.5 4.6 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SUR7 PF06687.12 KND91399.1 - 2.7e-34 118.7 15.4 3.5e-34 118.3 15.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family RCR PF12273.8 KND91399.1 - 0.017 15.8 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LapA_dom PF06305.11 KND91399.1 - 0.095 12.5 0.0 0.095 12.5 0.0 3.2 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF2534 PF10749.9 KND91399.1 - 1.8 8.8 7.4 0.52 10.5 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2534) WD40 PF00400.32 KND91400.1 - 1e-11 45.1 14.0 5.9e-06 26.9 0.0 9.2 11 0 0 11 11 11 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KND91400.1 - 0.011 14.4 0.0 0.26 10.0 0.0 3.1 3 0 0 3 3 3 0 Nup133 N terminal like Rrn6 PF10214.9 KND91400.1 - 0.16 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TFIIA PF03153.13 KND91402.1 - 2.7e-85 287.9 4.6 3.4e-85 287.6 4.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kelch_4 PF13418.6 KND91403.1 - 3.4e-28 97.4 6.4 5.3e-08 32.7 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KND91403.1 - 2.9e-24 84.6 1.4 6.2e-07 29.3 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 KND91403.1 - 2.2e-23 81.7 1.9 9.7e-05 22.5 0.0 4.9 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.25 KND91403.1 - 4.3e-21 74.2 0.3 2.9e-05 23.6 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 KND91403.1 - 4.7e-21 74.6 0.8 7.3e-07 29.3 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 KND91403.1 - 2.7e-19 68.3 2.5 0.00053 19.9 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 KND91403.1 - 5.1e-09 36.3 0.0 8.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 KND91403.1 - 0.19 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-C2H2 PF00096.26 KND91404.1 - 8.6e-05 22.8 10.9 0.11 13.0 0.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KND91404.1 - 0.00026 21.2 2.9 0.046 13.9 0.3 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KND91404.1 - 0.0022 18.7 11.7 0.55 11.2 1.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND91404.1 - 0.028 14.9 13.7 0.072 13.6 0.8 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KND91404.1 - 0.097 13.0 4.8 1.7 9.1 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Phosphoprotein PF00922.17 KND91404.1 - 0.12 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-C2H2_6 PF13912.6 KND91404.1 - 2.1 8.4 10.8 0.25 11.4 2.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2242 PF10001.9 KND91404.1 - 3.9 7.7 5.3 7.9 6.7 5.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) Kelch_1 PF01344.25 KND91405.1 - 2.2e-42 142.4 18.4 5.1e-09 35.6 0.6 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KND91405.1 - 1.1e-37 127.4 15.6 1.4e-07 31.4 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KND91405.1 - 1.8e-36 123.7 10.6 6e-07 29.6 0.0 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KND91405.1 - 8.3e-36 121.8 15.0 4e-07 29.9 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KND91405.1 - 1.9e-32 110.5 16.4 6.5e-07 29.4 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KND91405.1 - 4.6e-31 105.6 16.0 4.9e-07 29.5 0.3 6.5 6 0 0 6 6 6 6 Kelch motif ADH_N PF08240.12 KND91407.1 - 6.9e-18 64.5 1.5 9.6e-18 64.1 0.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND91407.1 - 1.4e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND91407.1 - 3.7e-06 26.6 0.6 0.001 18.6 0.4 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 KND91407.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ATP-synt_G PF04718.15 KND91408.1 - 3.2e-35 121.0 1.3 4.6e-35 120.4 0.6 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Collagen_mid PF15984.5 KND91408.1 - 0.052 13.3 0.9 0.11 12.3 0.3 1.6 1 1 1 2 2 2 0 Bacterial collagen, middle region CSTF_C PF14304.6 KND91408.1 - 0.074 12.7 0.4 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal SipA_VBS PF17985.1 KND91408.1 - 0.18 11.8 1.7 0.58 10.2 0.0 2.6 3 0 0 3 3 3 0 SipA vinculin binding site LEA_3 PF03242.13 KND91409.1 - 0.32 11.7 1.3 0.75 10.6 0.1 2.2 3 0 0 3 3 3 0 Late embryogenesis abundant protein RasGAP PF00616.19 KND91410.1 - 3.4e-50 170.6 0.0 2.4e-49 167.9 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KND91410.1 - 1.7e-17 63.8 0.6 1.7e-17 63.8 0.6 2.2 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 KND91410.1 - 1.9e-14 52.0 37.3 0.16 11.8 1.4 12.7 15 0 0 15 15 15 7 IQ calmodulin-binding motif CH PF00307.31 KND91410.1 - 1.5e-10 41.2 0.0 4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.15 KND91410.1 - 1.8 8.4 7.2 0.33 10.7 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator DUF155 PF02582.14 KND91411.1 - 5.5e-55 186.2 0.1 8.6e-55 185.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 LBP_BPI_CETP_C PF02886.17 KND91411.1 - 0.19 11.1 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain E1-E2_ATPase PF00122.20 KND91412.1 - 2e-50 170.8 0.4 6.2e-50 169.2 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KND91412.1 - 3.2e-46 155.6 0.6 3e-12 46.8 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KND91412.1 - 8.1e-38 130.8 1.3 1.8e-37 129.7 1.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND91412.1 - 2.5e-06 27.4 1.4 1.9e-05 24.5 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND91412.1 - 0.0033 17.8 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase U6-snRNA_bdg PF10596.9 KND91412.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 U6-snRNA interacting domain of PrP8 HAD_2 PF13419.6 KND91412.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aa_trans PF01490.18 KND91414.1 - 4.6e-16 58.5 24.3 2.9e-09 36.1 8.2 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein SLATT_fungal PF18142.1 KND91414.1 - 3.8 7.5 4.9 10 6.2 1.3 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain UDG PF03167.19 KND91415.1 - 6.8e-20 71.6 0.0 1e-19 71.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 KND91416.1 - 5.6e-56 189.9 0.0 7e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KND91416.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain DEAD PF00270.29 KND91417.1 - 3.2e-24 85.6 0.1 3.1e-23 82.4 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND91417.1 - 1.6e-23 83.1 0.0 4.2e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND91417.1 - 0.00092 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Vps8 PF12816.7 KND91418.1 - 7.8e-75 250.7 0.1 1.4e-74 249.9 0.1 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 PIG-P PF08510.12 KND91418.1 - 2.6e-50 169.4 0.2 7.5e-50 167.9 0.2 1.8 1 0 0 1 1 1 1 PIG-P Clathrin PF00637.20 KND91418.1 - 0.00052 19.9 0.2 0.38 10.6 0.0 3.7 4 0 0 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.32 KND91418.1 - 0.12 13.3 0.3 8.8 7.4 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DPM2 PF07297.12 KND91418.1 - 5.3 7.4 10.4 16 5.9 10.4 1.7 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2401 PF10287.9 KND91419.1 - 1.1e-90 303.3 1.2 1.6e-90 302.7 1.2 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 KND91419.1 - 4.9e-21 74.9 0.0 1.4e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Peptidase_M23 PF01551.22 KND91419.1 - 0.052 13.8 0.4 4.8 7.5 0.1 2.8 1 1 1 2 2 2 0 Peptidase family M23 Sex_peptide PF08138.11 KND91419.1 - 0.094 12.9 2.0 6.6 7.0 0.5 2.7 2 0 0 2 2 2 0 Sex peptide (SP) family HATPase_c PF02518.26 KND91421.1 - 1.4e-21 77.1 0.2 2.7e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KND91421.1 - 6.7e-21 74.6 0.1 1.5e-20 73.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 KND91421.1 - 2.8e-09 37.2 0.0 0.00018 21.7 0.0 3.0 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 KND91421.1 - 3e-08 33.6 0.2 9.2e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KND91421.1 - 3.8e-06 27.1 0.0 2.8e-05 24.3 0.0 2.6 2 1 1 3 3 3 1 PAS domain PAS PF00989.25 KND91421.1 - 0.00018 21.5 0.0 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 KND91421.1 - 0.00033 20.9 0.0 0.0009 19.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 KND91421.1 - 0.001 19.3 0.0 0.5 10.7 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 KND91421.1 - 0.0016 18.4 0.1 0.007 16.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain HATPase_c_3 PF13589.6 KND91421.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PH_6 PF15406.6 KND91422.1 - 9.8e-34 116.0 0.5 9.8e-34 116.0 0.5 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KND91422.1 - 0.0097 16.4 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Metallophos PF00149.28 KND91424.1 - 4.3e-34 118.8 0.1 1.2e-33 117.4 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KND91424.1 - 5.9e-16 58.6 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Aldedh PF00171.22 KND91426.1 - 1.9e-167 557.4 0.5 2.2e-167 557.2 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ASXH PF13919.6 KND91427.1 - 0.024 14.6 1.1 0.041 13.9 1.1 1.3 1 0 0 1 1 1 0 Asx homology domain META PF03724.16 KND91429.1 - 0.12 12.4 0.0 1.3 9.0 0.0 2.4 2 1 0 3 3 3 0 META domain DUF3752 PF12572.8 KND91430.1 - 5.5e-46 156.9 6.3 8.5e-46 156.2 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) tRNA-synt_2 PF00152.20 KND91431.1 - 7.8e-64 215.7 0.0 4.6e-53 180.3 0.0 2.1 1 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND91431.1 - 6.9e-09 35.6 0.2 1.2e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KND91431.1 - 3.5e-06 26.7 0.0 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Actin PF00022.19 KND91432.1 - 1.5e-148 494.8 0.0 1.7e-148 494.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND91432.1 - 9.2e-06 24.7 0.0 0.014 14.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Tti2 PF10521.9 KND91433.1 - 5.1e-69 232.9 0.0 1.4e-68 231.4 0.0 1.8 1 1 0 1 1 1 1 Tti2 family HEAT PF02985.22 KND91433.1 - 0.03 14.6 0.4 0.98 9.9 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat PolyA_pol PF01743.20 KND91434.1 - 4.7e-25 88.4 0.1 1.7e-24 86.7 0.1 2.0 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KND91434.1 - 1e-10 41.2 0.1 2.5e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Sec7 PF01369.20 KND91435.1 - 1.4e-63 213.9 0.0 2.4e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KND91435.1 - 3.7e-16 59.4 0.0 2.1e-15 57.0 0.0 2.4 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KND91435.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Syja_N PF02383.18 KND91436.1 - 1e-75 255.1 0.0 2e-75 254.1 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain WYL PF13280.6 KND91436.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 WYL domain Anp1 PF03452.14 KND91438.1 - 3.3e-115 384.0 1.8 1.3e-114 382.0 0.0 2.1 2 0 0 2 2 2 1 Anp1 DUF3040 PF11239.8 KND91438.1 - 0.052 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Smg8_Smg9 PF10220.9 KND91438.1 - 0.31 9.3 2.1 0.42 8.9 2.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Rad54_N PF08658.10 KND91438.1 - 0.55 10.4 5.4 1.3 9.2 5.4 1.6 1 1 0 1 1 1 0 Rad54 N terminal zf-C3HC4_3 PF13920.6 KND91439.1 - 6.7e-08 32.3 12.7 1.1e-07 31.6 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND91439.1 - 0.19 11.6 12.2 0.32 10.9 12.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_PH PF01138.21 KND91440.1 - 6.1e-26 91.5 0.0 1.5e-25 90.2 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNA_pol_Rpb8 PF03870.15 KND91441.1 - 3.3e-44 150.4 0.0 3.7e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 KND91441.1 - 4.8e-05 23.4 0.1 0.0036 17.4 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G tRNA_int_endo PF01974.17 KND91442.1 - 9.8e-11 41.6 0.0 2.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PAXNEB PF05625.11 KND91443.1 - 8e-95 318.1 0.0 9.4e-95 317.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Asp PF00026.23 KND91444.1 - 1.1e-62 212.3 0.0 1.9e-62 211.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease GTP_EFTU PF00009.27 KND91444.1 - 1.3e-58 197.8 0.1 2.1e-58 197.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KND91444.1 - 1.3e-31 108.9 0.0 2.7e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KND91444.1 - 7.4e-31 106.1 0.0 1.4e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KND91444.1 - 3.3e-23 81.5 0.0 7.2e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND91444.1 - 3.3e-13 49.8 0.1 6.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TAXi_N PF14543.6 KND91444.1 - 6.2e-12 46.1 0.5 5.2e-07 30.1 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal RF3_C PF16658.5 KND91444.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain TAXi_C PF14541.6 KND91444.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KND91444.1 - 0.064 13.9 0.1 18 6.0 0.0 3.4 3 0 0 3 3 3 0 Aspartyl protease MMR_HSR1 PF01926.23 KND91444.1 - 0.08 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_L23eN PF03939.13 KND91445.1 - 1.2e-26 92.7 9.0 1.2e-26 92.7 9.0 2.9 2 1 1 3 3 3 2 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KND91445.1 - 2.5e-16 59.8 0.8 5.5e-16 58.7 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Bmt2 PF11968.8 KND91447.1 - 2.1e-82 276.2 0.0 3e-82 275.7 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 KND91447.1 - 0.071 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 KND91448.1 - 1.6e-42 145.8 0.0 2.3e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.15 KND91449.1 - 1e-20 73.1 2.9 1.3e-20 72.8 2.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SPC12 PF06645.13 KND91450.1 - 9.9e-29 99.2 0.0 1.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) NAD_binding_8 PF13450.6 KND91452.1 - 3.4e-13 49.6 1.6 8.4e-13 48.4 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND91452.1 - 3.6e-09 36.3 0.0 6.7e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND91452.1 - 1.3e-08 34.8 4.9 3.4e-06 26.9 0.8 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND91452.1 - 2e-07 31.4 0.2 0.00059 20.3 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KND91452.1 - 3.9e-06 26.5 0.3 1.6e-05 24.5 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND91452.1 - 5.4e-06 25.8 1.3 8.8e-06 25.1 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KND91452.1 - 1e-05 24.4 0.2 0.00023 20.0 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KND91452.1 - 1.1e-05 24.7 0.0 3.8e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 KND91452.1 - 9.1e-05 21.9 0.1 0.0024 17.3 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KND91452.1 - 0.00063 18.7 0.3 0.0016 17.3 0.3 1.6 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 KND91452.1 - 0.0021 18.1 0.2 0.0083 16.1 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KND91452.1 - 0.0025 16.9 0.3 0.0037 16.4 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.6 KND91452.1 - 0.029 13.5 0.0 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KND91452.1 - 0.038 13.2 1.2 0.36 10.0 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KND91452.1 - 0.052 12.6 0.6 0.11 11.5 0.6 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KND91452.1 - 0.083 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-rbx1 PF12678.7 KND91453.1 - 1e-24 86.5 12.6 1.5e-24 86.0 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KND91453.1 - 3.8e-17 62.1 9.8 4.9e-17 61.8 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KND91453.1 - 2.9e-06 27.5 14.0 0.00011 22.5 14.0 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND91453.1 - 4.1e-05 23.3 2.7 4.1e-05 23.3 2.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND91453.1 - 0.0021 17.9 11.5 0.037 13.9 11.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Calycin_like PF13944.6 KND91453.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Calycin-like beta-barrel domain zf-C3HC4_3 PF13920.6 KND91453.1 - 0.21 11.5 10.3 0.7 9.8 4.1 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND91453.1 - 0.3 11.1 6.9 1.1 9.3 6.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 KND91453.1 - 0.34 10.7 16.0 30 4.5 16.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KND91453.1 - 1 9.6 9.3 5.8 7.2 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KND91453.1 - 1.8 8.3 14.9 2.6e+02 1.3 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Tyr-DNA_phospho PF06087.12 KND91454.1 - 5.7e-87 292.4 0.0 6.6e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KND91454.1 - 0.00058 19.6 1.3 0.00058 19.6 1.3 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KND91454.1 - 0.0022 17.9 0.0 0.0086 16.0 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain PNRC PF15365.6 KND91455.1 - 1.5e-08 34.2 5.4 1.5e-08 34.2 5.4 5.8 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif Methyltransf_25 PF13649.6 KND91456.1 - 1.1e-12 48.5 0.0 1.8e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND91456.1 - 2.3e-10 40.6 0.0 3.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91456.1 - 5.2e-10 40.0 0.1 9.5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND91456.1 - 7.1e-10 38.6 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KND91456.1 - 4.4e-09 36.9 0.0 8.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND91456.1 - 6.4e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KND91456.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 KND91456.1 - 2.4e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 KND91456.1 - 8.3e-05 22.1 0.1 0.0028 17.1 0.0 2.6 2 1 1 3 3 3 1 Putative methyltransferase Methyltransf_15 PF09445.10 KND91456.1 - 0.0059 16.2 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 KND91456.1 - 0.016 14.9 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KND91456.1 - 0.056 13.6 0.1 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KND91456.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 KND91456.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pkinase_Tyr PF07714.17 KND91457.1 - 2.7e-14 53.1 0.0 1.7e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KND91457.1 - 5.2e-11 42.4 0.0 2.2e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND91457.1 - 0.0051 16.2 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND91457.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 RIO1 family PUL PF08324.11 KND91459.1 - 1.7e-58 198.1 0.0 4e-58 196.8 0.0 1.6 2 0 0 2 2 2 1 PUL domain PFU PF09070.11 KND91459.1 - 3.4e-44 149.7 0.5 7e-44 148.7 0.5 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KND91459.1 - 1.4e-32 111.2 13.6 4.2e-07 30.5 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91459.1 - 0.00039 20.6 1.0 1 9.7 0.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KND91459.1 - 0.083 13.4 0.9 0.6 10.7 0.0 2.9 2 1 1 3 3 3 0 PQQ-like domain WD40 PF00400.32 KND91460.1 - 5e-27 93.6 4.4 3.5e-10 40.3 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91460.1 - 6.9e-07 29.5 0.0 0.033 14.5 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND91460.1 - 0.0021 17.1 0.0 0.055 12.4 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VIT PF08487.10 KND91461.1 - 6.1e-33 113.3 0.0 2.3e-32 111.5 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KND91461.1 - 2.4e-25 89.3 0.0 4.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KND91461.1 - 1.7e-15 56.7 0.0 4.3e-15 55.4 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 KND91461.1 - 7.9e-09 36.0 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KND91461.1 - 1.8e-05 25.4 0.0 4.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KND91461.1 - 0.00045 19.7 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Coleoptericin PF06286.11 KND91464.1 - 0.39 10.8 3.2 0.22 11.6 1.6 1.4 1 1 0 1 1 1 0 Coleoptericin APH PF01636.23 KND91465.1 - 2.2e-11 44.2 0.8 4.4e-10 39.9 0.8 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND91465.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ORF_2_N PF18492.1 KND91465.1 - 0.17 12.1 0.2 0.36 11.0 0.2 1.5 1 0 0 1 1 1 0 Open reading frame 2 N-terminal domain F1F0-ATPsyn_F PF10791.9 KND91466.1 - 9.4e-38 128.6 0.1 1.2e-37 128.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi MOZ_SAS PF01853.18 KND91468.1 - 7.6e-81 270.0 0.2 1.1e-80 269.6 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KND91468.1 - 1e-21 76.3 0.4 1.8e-21 75.4 0.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KND91468.1 - 4.1e-17 61.8 0.0 1.5e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KND91468.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND91468.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2314 PF10077.9 KND91468.1 - 0.037 14.1 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Glyco_hydro_125 PF06824.11 KND91469.1 - 6.1e-180 598.5 0.0 7e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aminotran_1_2 PF00155.21 KND91470.1 - 1.6e-25 90.1 0.0 2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KND91470.1 - 0.21 10.3 0.0 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase CDC27 PF09507.10 KND91471.1 - 1.2e-75 255.6 39.6 3.3e-74 250.8 39.6 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC45 PF02724.14 KND91471.1 - 0.8 7.9 11.4 1.1 7.4 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3602 PF12223.8 KND91471.1 - 4.3 8.0 10.5 6.4 7.5 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) MCM PF00493.23 KND91472.1 - 2e-103 344.3 0.8 3.5e-103 343.5 0.3 1.6 1 1 1 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KND91472.1 - 2.6e-38 130.7 0.1 5.1e-38 129.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KND91472.1 - 3.4e-32 110.9 0.1 7.9e-32 109.7 0.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KND91472.1 - 6.8e-25 87.3 1.3 2.6e-24 85.4 0.2 2.6 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 KND91472.1 - 4e-24 85.2 0.2 1.6e-23 83.2 0.2 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND91472.1 - 3.2e-07 29.9 0.0 8.7e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KND91472.1 - 0.0012 18.8 0.3 0.0034 17.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND91472.1 - 0.0014 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain CCDC53 PF10152.9 KND91472.1 - 0.064 13.7 0.5 0.27 11.6 0.1 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex AAA_5 PF07728.14 KND91472.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 KND91472.1 - 0.13 12.4 1.5 0.35 11.0 1.5 1.7 1 0 0 1 1 1 0 GidA associated domain RNase_T PF00929.24 KND91474.1 - 1.4e-10 41.9 0.0 4.6e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease CMAS PF02353.20 KND91475.1 - 3.2e-70 236.5 0.0 5.5e-70 235.8 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KND91475.1 - 1.7e-12 47.9 0.0 3.3e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91475.1 - 5.4e-12 46.2 0.0 1e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND91475.1 - 2.9e-10 40.2 0.0 5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91475.1 - 6.5e-08 32.5 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91475.1 - 8.7e-05 23.2 0.0 0.00017 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND91475.1 - 0.00016 21.5 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KND91475.1 - 0.022 14.5 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 KND91475.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GARS_A PF01071.19 KND91476.1 - 1.7e-83 279.2 0.0 2.8e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KND91476.1 - 5.4e-36 123.3 0.1 4.2e-35 120.4 0.0 2.5 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KND91476.1 - 2e-34 119.0 0.0 4.4e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KND91476.1 - 1.1e-23 83.3 3.1 1.1e-23 83.2 0.2 2.7 4 0 0 4 4 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KND91476.1 - 8.1e-15 55.3 1.0 2.6e-14 53.6 1.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KND91476.1 - 0.00032 20.2 0.1 0.0006 19.4 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 KND91476.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KND91476.1 - 0.0034 17.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 KND91476.1 - 0.0072 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KND91476.1 - 0.039 13.6 0.3 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 KND91476.1 - 0.041 13.5 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF1188 PF06690.11 KND91476.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) TRAPP PF04051.16 KND91477.1 - 4.5e-36 123.8 0.0 8e-36 122.9 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Nucleoporin_FG PF13634.6 KND91478.1 - 1.8e-18 67.2 99.8 1.4e-08 35.5 27.2 4.3 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF3584 PF12128.8 KND91478.1 - 0.013 13.1 1.1 0.11 10.0 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Apolipoprotein PF01442.18 KND91478.1 - 0.03 14.2 0.6 0.06 13.2 0.6 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 KND91478.1 - 0.63 10.1 2.4 4.5 7.3 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fip1 PF05182.13 KND91479.1 - 3.6e-20 71.2 0.9 6.5e-20 70.4 0.9 1.5 1 0 0 1 1 1 1 Fip1 motif Astro_capsid_p PF12226.8 KND91479.1 - 9.7 5.2 10.6 16 4.5 10.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein F-box-like PF12937.7 KND91480.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Glyco_hydro_18 PF00704.28 KND91481.1 - 8.3e-18 65.2 0.3 3.4e-17 63.2 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 2-oxoacid_dh PF00198.23 KND91482.1 - 6.8e-75 251.5 0.3 8.7e-75 251.2 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KND91482.1 - 8.8e-20 70.3 1.1 2e-19 69.2 1.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KND91482.1 - 9.3e-14 51.5 0.7 2.3e-13 50.2 0.7 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KND91482.1 - 0.03 14.8 3.1 0.039 14.4 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) S4_2 PF13275.6 KND91482.1 - 0.058 13.2 0.3 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 S4 domain Sec7 PF01369.20 KND91483.1 - 3.8e-69 232.0 4.0 9.3e-69 230.8 0.4 3.0 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 KND91483.1 - 3.3e-32 110.2 10.8 7.1e-32 109.1 0.0 5.7 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 KND91483.1 - 2.6e-28 98.9 5.5 1.5e-25 90.0 1.6 4.2 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 KND91483.1 - 1.5e-22 80.2 2.6 3.9e-21 75.5 0.2 3.3 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RIH_assoc PF08454.11 KND91483.1 - 0.054 13.3 0.4 0.53 10.2 0.1 2.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated M20_dimer PF07687.14 KND91484.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain RNA_pol_3_Rpc31 PF11705.8 KND91485.1 - 1.7e-59 201.9 0.7 1.9e-59 201.7 0.7 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PBD PF00786.28 KND91486.1 - 0.033 14.5 0.1 0.096 13.1 0.1 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain Mg_trans_NIPA PF05653.14 KND91487.1 - 3.6e-58 197.0 12.2 3.3e-56 190.6 9.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KND91487.1 - 0.015 15.5 28.5 0.023 14.8 2.1 4.1 3 1 1 4 4 4 0 EamA-like transporter family DUF4131 PF13567.6 KND91487.1 - 0.093 12.4 7.9 0.16 11.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) YfhO PF09586.10 KND91487.1 - 0.098 10.9 4.4 0.15 10.3 4.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4149 PF13664.6 KND91487.1 - 0.17 12.2 8.3 3.1 8.2 0.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) DUF1461 PF07314.11 KND91487.1 - 1.2 9.1 7.8 0.62 9.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF2101 PF09874.9 KND91487.1 - 2 8.1 5.8 2.4 7.8 3.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) TssN PF17555.2 KND91487.1 - 3.3 7.0 8.5 5.6 6.3 8.3 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN DUF2569 PF10754.9 KND91487.1 - 6.2 7.3 10.3 0.51 10.8 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Cnd3 PF12719.7 KND91488.1 - 5.4e-89 298.3 0.7 3.5e-88 295.6 0.1 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 KND91488.1 - 6.3e-09 36.1 5.2 0.00011 22.5 1.2 4.8 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.22 KND91488.1 - 3.3e-06 26.9 9.5 0.078 13.3 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 KND91488.1 - 0.0022 18.1 3.6 0.65 10.0 0.0 4.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KND91488.1 - 0.12 12.9 0.0 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KND91488.1 - 6.5 7.4 9.3 12 6.5 0.0 5.6 7 0 0 7 7 7 0 HEAT-like repeat Phosphodiest PF01663.22 KND91489.1 - 2.1e-08 34.1 0.5 1.2e-06 28.4 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND91489.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Sulfatase DUF4049 PF13258.6 KND91489.1 - 0.15 11.1 0.0 4.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) Metalloenzyme PF01676.18 KND91489.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily HTH_CodY PF08222.11 KND91490.1 - 0.15 11.6 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 CodY helix-turn-helix domain RRM_1 PF00076.22 KND91491.1 - 4.7e-57 189.7 0.2 5e-16 58.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 KND91491.1 - 9.4e-05 22.3 0.7 0.066 13.0 0.1 3.0 2 2 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 KND91491.1 - 0.016 15.3 0.2 24 5.2 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif RRM_5 PF13893.6 KND91491.1 - 0.042 13.5 0.0 0.27 10.8 0.0 2.4 3 1 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KND91491.1 - 0.044 13.8 0.0 12 6.0 0.0 2.7 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_occluded PF16842.5 KND91491.1 - 0.13 12.2 0.0 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Occluded RNA-recognition motif Methyltransf_25 PF13649.6 KND91493.1 - 0.00028 21.5 0.0 0.00052 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91493.1 - 0.0024 18.5 0.1 0.0091 16.6 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND91493.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91493.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2423 PF10338.9 KND91494.1 - 4e-18 65.4 7.0 4e-18 65.4 7.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.6 KND91495.1 - 1.4e-37 129.3 0.1 2.8e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KND91495.1 - 3e-22 78.1 5.5 5.7e-22 77.2 5.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KND91495.1 - 4.7e-06 26.3 1.1 1.1e-05 25.2 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 KND91495.1 - 5.3e-05 22.9 0.1 0.00011 21.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 KND91495.1 - 0.0093 16.0 0.6 0.029 14.4 0.4 1.9 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger PBP1_TM PF14812.6 KND91495.1 - 0.053 13.9 0.5 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OMP_b-brl_3 PF14905.6 KND91495.1 - 0.072 12.1 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family zf-C3HC4_4 PF15227.6 KND91495.1 - 0.13 12.4 5.2 0.28 11.4 5.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KND91495.1 - 0.54 10.3 3.1 1 9.4 3.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KND91495.1 - 2 8.8 4.5 3.7 8.0 4.5 1.4 1 0 0 1 1 1 0 Ring finger domain NDUF_B4 PF07225.12 KND91496.1 - 0.0081 16.1 0.1 0.0088 15.9 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Prp18 PF02840.15 KND91497.1 - 7e-51 172.0 0.0 7e-51 172.0 0.0 1.8 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 KND91497.1 - 9e-10 37.9 4.5 9.1e-10 37.9 0.1 2.6 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Borrelia_P83 PF05262.11 KND91497.1 - 0.52 8.7 8.6 0.6 8.5 8.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RPN7 PF10602.9 KND91499.1 - 3.3e-45 153.9 0.0 5.4e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KND91499.1 - 3.3e-12 46.8 0.0 9.9e-12 45.3 0.0 1.8 2 0 0 2 2 2 1 PCI domain DHC_N2 PF08393.13 KND91499.1 - 0.0015 17.7 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 dsDNA_bind PF01984.20 KND91499.1 - 0.04 14.2 0.9 13 6.1 0.5 2.6 1 1 1 2 2 2 0 Double-stranded DNA-binding domain TPR_2 PF07719.17 KND91499.1 - 0.081 13.1 0.2 34 4.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KND91500.1 - 2.1e-24 86.0 0.0 3.3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91500.1 - 9.8e-11 41.6 13.6 1.9e-10 40.7 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KND91500.1 - 0.18 12.0 0.1 0.5 10.6 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Peptidase_M24 PF00557.24 KND91501.1 - 2.1e-60 204.0 0.1 3e-60 203.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KND91501.1 - 6.5e-20 71.1 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TOBE PF03459.17 KND91501.1 - 0.14 12.4 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 TOBE domain Lectin_leg-like PF03388.13 KND91502.1 - 1.4e-27 96.6 0.0 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family FUSC PF04632.12 KND91502.1 - 0.00019 20.1 3.7 0.00028 19.6 3.7 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family IFT57 PF10498.9 KND91502.1 - 0.00093 18.3 3.0 0.0014 17.7 3.0 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Golgin_A5 PF09787.9 KND91502.1 - 0.0033 16.9 4.7 0.0049 16.4 4.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2353 PF09789.9 KND91502.1 - 0.0035 16.8 4.1 0.005 16.2 4.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.6 KND91502.1 - 0.011 15.8 4.0 0.016 15.2 4.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 KND91502.1 - 0.011 15.1 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KND91502.1 - 0.015 15.8 0.8 0.023 15.2 0.8 1.2 1 0 0 1 1 1 0 Fez1 FlxA PF14282.6 KND91502.1 - 0.019 14.9 6.1 0.044 13.8 6.1 1.5 1 0 0 1 1 1 0 FlxA-like protein Fmp27_WPPW PF10359.9 KND91502.1 - 0.037 12.9 5.8 0.048 12.5 5.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Collectrin PF16959.5 KND91502.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Renal amino acid transporter COMM_domain PF07258.14 KND91502.1 - 0.043 13.9 0.3 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 COMM domain Stevor PF17410.2 KND91502.1 - 0.059 12.9 2.8 1.9 8.0 0.0 2.4 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame BORCS7 PF16088.5 KND91502.1 - 0.065 13.5 2.6 0.13 12.5 2.6 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 Baculo_PEP_C PF04513.12 KND91502.1 - 0.078 13.0 2.7 0.25 11.4 0.9 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI_PP_C PF18365.1 KND91502.1 - 0.082 12.9 0.7 0.14 12.1 0.7 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Occludin_ELL PF07303.13 KND91502.1 - 0.088 13.5 3.0 0.19 12.5 3.0 1.5 1 0 0 1 1 1 0 Occludin homology domain FPP PF05911.11 KND91502.1 - 0.095 10.9 3.0 0.13 10.5 3.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil UPF0184 PF03670.13 KND91502.1 - 0.12 12.8 1.4 0.24 11.8 1.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) TMPIT PF07851.13 KND91502.1 - 0.13 11.5 3.0 0.18 11.0 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin-6_N PF09177.11 KND91502.1 - 0.13 12.8 1.0 0.35 11.5 1.0 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Laminin_II PF06009.12 KND91502.1 - 0.15 12.1 2.0 0.24 11.4 2.0 1.2 1 0 0 1 1 1 0 Laminin Domain II Sigma70_ner PF04546.13 KND91502.1 - 0.16 11.8 2.4 0.24 11.3 2.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Flagellin_N PF00669.20 KND91502.1 - 0.24 11.5 3.4 0.42 10.7 3.4 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Prefoldin_2 PF01920.20 KND91502.1 - 0.25 11.3 5.3 9.3 6.3 1.0 2.7 1 1 1 2 2 2 0 Prefoldin subunit EzrA PF06160.12 KND91502.1 - 0.27 9.4 2.7 0.38 8.9 2.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.11 KND91502.1 - 0.28 11.5 1.5 1.1 9.5 1.5 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 KND91502.1 - 0.31 9.6 0.8 0.45 9.1 0.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 KND91502.1 - 0.31 11.1 3.1 0.47 10.5 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 KND91502.1 - 0.32 8.9 1.8 0.44 8.5 1.8 1.1 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.10 KND91502.1 - 0.37 11.0 6.6 0.11 12.7 3.4 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family IMD PF08397.11 KND91502.1 - 0.47 9.8 3.5 0.74 9.1 3.5 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain CSN5_C PF18323.1 KND91502.1 - 0.8 10.7 4.5 5.7 7.9 0.7 2.4 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF1515 PF07439.11 KND91502.1 - 1.5 8.9 3.0 3.5 7.7 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Syntaxin_2 PF14523.6 KND91502.1 - 1.8 9.0 7.1 5.8 7.3 2.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein TolA_bind_tri PF16331.5 KND91502.1 - 3.3 7.9 8.2 4.1 7.5 1.9 2.8 1 1 0 2 2 2 0 TolA binding protein trimerisation Alg6_Alg8 PF03155.15 KND91503.1 - 5.4e-173 576.4 29.5 6.3e-173 576.2 29.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WSD PF15613.6 KND91504.1 - 1.3e-17 64.0 0.1 1.3e-17 64.0 0.1 3.6 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KND91504.1 - 1.1e-16 60.8 1.1 1.9e-16 60.1 1.1 1.4 1 0 0 1 1 1 1 DDT domain WAC_Acf1_DNA_bd PF10537.9 KND91504.1 - 1.7e-12 47.7 2.4 3.1e-12 46.9 0.0 2.6 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM1 PF15612.6 KND91504.1 - 3.4e-12 45.6 0.1 1.1e-10 40.8 0.0 2.7 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop53 PF07767.11 KND91504.1 - 2.7 7.3 54.9 0.26 10.6 33.1 2.7 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) PROCN PF08083.11 KND91505.1 - 2.8e-234 777.2 8.2 2.8e-234 777.2 8.2 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KND91505.1 - 2.2e-126 420.1 1.1 4.5e-126 419.1 1.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KND91505.1 - 2.3e-88 294.1 2.6 7e-88 292.6 2.6 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KND91505.1 - 8.6e-78 259.5 3.7 8.6e-78 259.5 3.7 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KND91505.1 - 1.3e-70 235.7 0.1 2.5e-70 234.7 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 KND91505.1 - 1e-44 151.4 0.8 2.2e-44 150.3 0.1 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 KND91505.1 - 1.8e-44 150.0 0.1 4.7e-44 148.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 SAP18 PF06487.12 KND91506.1 - 1.1e-41 142.3 0.0 1.4e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Phage_holin_3_6 PF07332.11 KND91507.1 - 0.27 11.3 19.4 0.12 12.5 6.5 3.2 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III BT1 PF03092.16 KND91508.1 - 0.018 13.3 0.0 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 BT1 family Podoplanin PF05808.11 KND91508.1 - 0.028 14.5 1.2 0.083 13.0 1.2 1.7 1 0 0 1 1 1 0 Podoplanin Pkinase PF00069.25 KND91509.1 - 1.1e-51 175.8 0.0 1.8e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91509.1 - 3.3e-19 69.2 0.2 6.1e-19 68.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KND91509.1 - 0.074 13.0 0.3 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family HhH-GPD PF00730.25 KND91511.1 - 1.1e-15 58.1 0.0 5.6e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Recep_L_domain PF01030.24 KND91512.1 - 0.029 14.5 13.9 0.07 13.3 1.2 4.2 1 1 2 4 4 4 0 Receptor L domain Snf7 PF03357.21 KND91513.1 - 1.4e-30 106.2 20.9 1.4e-30 106.2 20.9 2.0 1 1 1 2 2 2 1 Snf7 FMN_bind PF04205.14 KND91513.1 - 0.041 14.5 0.4 0.078 13.6 0.4 1.5 1 1 0 1 1 1 0 FMN-binding domain NAPRTase_N PF17767.1 KND91513.1 - 0.089 13.2 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Allexi_40kDa PF05549.11 KND91513.1 - 1.5 8.2 7.8 2.1 7.8 7.2 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein NPL PF17800.1 KND91513.1 - 1.8 9.1 4.2 0.42 11.2 0.5 1.8 1 1 1 2 2 2 0 Nucleoplasmin-like domain Anp1 PF03452.14 KND91514.1 - 2e-108 361.8 0.0 2.5e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 G-patch PF01585.23 KND91515.1 - 9e-14 51.1 0.1 9.2e-13 47.9 0.0 2.6 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 KND91515.1 - 0.00046 20.0 0.1 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND91515.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DEAD PF00270.29 KND91516.1 - 3.7e-34 118.0 0.0 2.2e-33 115.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND91516.1 - 1.2e-24 86.8 0.0 2.7e-24 85.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND91516.1 - 0.00076 19.5 0.0 0.0023 18.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KND91516.1 - 0.012 15.9 0.0 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KND91516.1 - 0.043 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 KND91517.1 - 7.5e-05 22.8 11.3 0.00013 22.0 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EPL1 PF10513.9 KND91517.1 - 0.0034 17.8 9.8 0.0054 17.1 9.8 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like DDHD PF02862.17 KND91517.1 - 0.0035 17.5 9.1 0.0055 16.9 9.1 1.3 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 KND91517.1 - 0.0047 17.0 40.6 0.0092 16.0 40.6 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KND91517.1 - 0.023 15.3 28.2 0.023 15.3 28.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_11 PF13086.6 KND91517.1 - 0.17 11.7 16.8 0.26 11.0 16.8 1.3 1 0 0 1 1 1 0 AAA domain SMN PF06003.12 KND91517.1 - 0.23 10.7 7.9 0.45 9.7 7.9 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Lin-8 PF03353.15 KND91517.1 - 0.25 10.9 20.6 0.43 10.1 20.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 KND91517.1 - 0.25 9.6 35.5 0.36 9.0 35.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 KND91517.1 - 0.28 10.5 22.6 0.43 9.9 22.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 KND91517.1 - 0.38 10.9 14.8 0.64 10.2 14.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Endostatin PF06482.11 KND91517.1 - 0.38 10.2 22.2 0.69 9.3 22.2 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4647 PF15504.6 KND91517.1 - 0.43 9.6 21.9 0.61 9.1 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SpoIIP PF07454.11 KND91517.1 - 0.76 9.2 18.6 1.1 8.7 18.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PTPRCAP PF15713.5 KND91517.1 - 0.86 9.9 17.8 1.7 9.0 17.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ndc1_Nup PF09531.10 KND91517.1 - 0.9 8.2 15.8 1.3 7.7 15.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 KND91517.1 - 1.2 8.1 24.0 1.7 7.5 24.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF913 PF06025.12 KND91517.1 - 1.2 8.0 12.0 1.7 7.5 12.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 KND91517.1 - 1.3 6.0 20.6 1.7 5.7 20.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 KND91517.1 - 1.7 8.9 22.1 3.6 7.8 22.1 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein ALMT PF11744.8 KND91517.1 - 1.8 7.3 16.3 2.5 6.8 16.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 KND91517.1 - 1.9 6.5 16.7 2.8 5.9 16.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.13 KND91517.1 - 1.9 8.3 20.3 3.3 7.6 20.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NARP1 PF12569.8 KND91517.1 - 2 7.2 18.5 2.8 6.7 18.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 KND91517.1 - 3 6.5 18.2 5.2 5.7 18.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 KND91517.1 - 3.1 6.5 25.2 4.4 6.0 25.2 1.1 1 0 0 1 1 1 0 Presenilin YABBY PF04690.13 KND91517.1 - 3.2 8.3 16.5 6 7.4 16.5 1.4 1 0 0 1 1 1 0 YABBY protein BORG_CEP PF14957.6 KND91517.1 - 3.4 8.8 13.2 8 7.6 13.2 1.6 1 0 0 1 1 1 0 Cdc42 effector Zip PF02535.22 KND91517.1 - 3.6 6.7 10.9 4.9 6.3 10.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 KND91517.1 - 4.1 6.8 15.7 6.2 6.3 15.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Band_3_cyto PF07565.13 KND91517.1 - 5.4 6.7 18.5 9 6.0 18.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 KND91517.1 - 5.7 5.8 20.1 7.6 5.4 20.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TERB2 PF15101.6 KND91517.1 - 5.8 6.9 25.7 12 5.9 25.7 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 KND91517.1 - 5.9 6.1 18.4 10 5.4 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3306 PF11748.8 KND91517.1 - 6.9 7.6 18.5 8.4 7.3 16.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Baculo_PP31 PF05311.11 KND91517.1 - 7.9 5.9 18.0 13 5.2 18.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4746 PF15928.5 KND91517.1 - 8.3 5.7 14.2 12 5.2 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 KND91517.1 - 8.5 4.5 16.5 12 4.0 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Peroxin-13_N PF04088.13 KND91517.1 - 8.9 6.6 8.9 24 5.2 8.9 1.8 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CLN3 PF02487.17 KND91519.1 - 2.4e-159 530.7 4.1 2.8e-159 530.4 4.1 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KND91519.1 - 1.7e-05 24.0 23.5 2.1e-05 23.6 7.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3040 PF11239.8 KND91519.1 - 4.5 7.6 6.1 1.4 9.2 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) MFS_1 PF07690.16 KND91520.1 - 1.1e-13 50.9 18.3 1.3e-13 50.6 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91520.1 - 6.3e-05 22.0 5.3 0.00012 21.1 5.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_34 PF05637.12 KND91521.1 - 3.5e-07 30.2 1.3 3.7e-06 26.8 1.3 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 KND91521.1 - 1e-05 25.6 0.0 2.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 KND91521.1 - 0.0061 16.2 0.5 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF273 TMEM171 PF15471.6 KND91521.1 - 0.25 10.3 0.2 0.39 9.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Col_cuticle_N PF01484.17 KND91521.1 - 0.52 10.4 5.6 8.3 6.6 0.7 2.3 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Rxt3 PF08642.10 KND91522.1 - 2.6e-43 147.8 1.4 1.7e-42 145.2 0.0 2.8 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KND91522.1 - 7.9e-05 22.7 0.0 0.0041 17.2 0.0 2.3 2 0 0 2 2 2 1 LCCL domain FPN1 PF06963.12 KND91523.1 - 3.2e-112 375.3 12.2 4.6e-112 374.8 12.2 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CTP_transf_like PF01467.26 KND91524.1 - 4.1e-08 33.5 0.0 1e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 KND91524.1 - 0.0034 17.3 0.0 0.0046 16.8 0.0 1.1 1 0 0 1 1 1 1 FAD synthetase HIGH_NTase1 PF05636.11 KND91524.1 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase DUF1674 PF07896.12 KND91525.1 - 3.1e-17 62.8 6.8 7.4e-17 61.6 6.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Chitin_synth_1 PF01644.17 KND91526.1 - 5e-68 228.2 0.0 7.5e-68 227.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KND91526.1 - 1.7e-27 95.1 0.1 3.3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KND91526.1 - 8.8e-26 90.6 0.1 3.7e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KND91526.1 - 3.7e-07 30.3 9.0 4.7e-06 26.6 9.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KND91526.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Opy2 PF09463.10 KND91527.1 - 5.1e-07 29.9 18.2 8e-07 29.3 18.2 1.3 1 0 0 1 1 1 1 Opy2 protein Amnionless PF14828.6 KND91527.1 - 0.074 11.9 0.3 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 Amnionless Ras PF00071.22 KND91528.1 - 2.4e-51 173.6 0.0 4.7e-51 172.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KND91528.1 - 1.9e-17 63.6 0.0 1.9e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND91528.1 - 0.0013 18.2 0.0 0.0036 16.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KND91528.1 - 0.023 14.6 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 KND91528.1 - 0.035 13.6 0.1 0.37 10.3 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Abhydrolase_4 PF08386.10 KND91528.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein AAA_16 PF13191.6 KND91528.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KND91528.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydrolase PF00702.26 KND91529.1 - 2.2e-11 44.5 0.0 2.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND91529.1 - 6.2e-08 32.9 0.0 1.2e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND91529.1 - 6.6e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like TipAS PF07739.13 KND91529.1 - 0.061 13.9 1.1 2.2 8.9 0.0 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain GDPD_2 PF13653.6 KND91529.1 - 0.062 13.8 0.2 0.33 11.5 0.2 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Rep_fac-A_C PF08646.10 KND91530.1 - 2.5e-10 40.3 0.1 2.7e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor-A C terminal domain DUF2237 PF09996.9 KND91530.1 - 0.14 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Aldedh PF00171.22 KND91531.1 - 1.1e-10 40.7 1.7 1.5e-05 23.7 0.4 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Tfb5 PF06331.12 KND91531.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 PALP PF00291.25 KND91532.1 - 5.6e-60 203.2 7.4 6.7e-60 203.0 7.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3343 PF11823.8 KND91532.1 - 0.04 13.4 0.1 0.2 11.1 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3343) UQ_con PF00179.26 KND91533.1 - 2.2e-36 124.6 0.0 3.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_MLP1_2 PF07926.12 KND91534.1 - 6.2e-05 23.1 18.5 0.0043 17.1 4.0 2.3 1 1 0 2 2 2 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KND91534.1 - 0.00012 22.6 12.5 0.00023 21.7 12.5 1.3 1 0 0 1 1 1 1 Fez1 DivIC PF04977.15 KND91534.1 - 0.18 11.6 4.0 0.084 12.7 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 KND91534.1 - 0.22 11.4 9.3 0.016 15.0 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FmiP_Thoc5 PF09766.9 KND91534.1 - 0.59 9.4 7.4 0.068 12.4 2.2 1.9 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 UPF0242 PF06785.11 KND91534.1 - 0.64 10.1 6.3 1.1 9.4 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 KND91534.1 - 0.66 10.2 6.0 0.85 9.9 5.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KND91534.1 - 0.94 8.3 12.9 1.5 7.6 12.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KND91534.1 - 1.1 9.4 19.3 0.75 10.0 10.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2959 PF11172.8 KND91534.1 - 1.9 8.6 7.8 3.2 7.8 5.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DUF4407 PF14362.6 KND91534.1 - 2.9 7.2 5.8 4.4 6.6 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 KND91534.1 - 3.5 8.0 11.8 6.3 7.2 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) ADIP PF11559.8 KND91534.1 - 4.7 7.3 18.8 7.9 6.6 3.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 KND91534.1 - 4.8 7.6 9.9 0.84 10.0 4.6 2.3 1 1 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 KND91534.1 - 6.3 7.2 12.8 18 5.8 8.8 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 KND91534.1 - 8.4 5.7 15.3 62 2.8 15.3 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPMT PF05724.11 KND91535.1 - 1.1e-27 97.1 0.0 6.3e-27 94.7 0.0 1.9 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 KND91535.1 - 2.4e-07 31.4 0.0 6.3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91535.1 - 3.6e-06 27.5 0.0 1.1e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND91535.1 - 4.3e-06 26.7 0.0 6.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91535.1 - 0.00026 20.8 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91535.1 - 0.0066 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KND91535.1 - 0.021 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ank_2 PF12796.7 KND91537.1 - 3.3e-14 53.2 0.9 1.6e-06 28.6 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND91537.1 - 2.5e-10 39.7 0.0 0.001 19.3 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 KND91537.1 - 4.8e-09 36.6 0.1 1.2e-05 25.7 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KND91537.1 - 1.4e-08 34.8 0.3 0.00036 20.8 0.1 4.7 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KND91537.1 - 1.1e-05 25.6 0.6 0.022 15.1 0.1 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF1304 PF06993.12 KND91538.1 - 0.25 11.3 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Lsm_interact PF05391.11 KND91538.1 - 1.2 8.7 6.9 0.17 11.4 2.0 2.1 2 0 0 2 2 2 0 Lsm interaction motif Sugar_tr PF00083.24 KND91540.1 - 6e-74 249.5 28.9 6.9e-74 249.3 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91540.1 - 5.9e-12 45.2 52.8 8.1e-11 41.4 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND91540.1 - 0.0065 15.1 27.2 0.02 13.5 6.8 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein Inositol_P PF00459.25 KND91543.1 - 4.4e-39 134.6 0.0 1.2e-38 133.3 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Mob1_phocein PF03637.17 KND91544.1 - 3.3e-37 128.1 0.0 4.7e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family PAGK PF15284.6 KND91544.1 - 0.13 12.1 0.1 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Phage-encoded virulence factor ABC_tran PF00005.27 KND91546.1 - 1.5e-47 161.6 0.1 7.5e-24 84.8 0.0 3.9 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KND91546.1 - 7.1e-31 106.1 1.8 1.3e-30 105.3 0.2 2.4 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 KND91546.1 - 7.9e-19 68.6 0.0 0.0019 18.1 0.0 5.2 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND91546.1 - 2.7e-15 56.4 0.1 0.00015 21.2 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND91546.1 - 7.2e-09 35.3 0.0 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND91546.1 - 4.6e-08 33.2 0.0 0.00054 19.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KND91546.1 - 1.3e-07 32.3 0.3 0.00026 21.6 0.2 3.1 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 KND91546.1 - 2e-07 31.1 0.0 0.0026 17.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KND91546.1 - 6.8e-07 29.6 0.0 0.015 15.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KND91546.1 - 1.3e-06 28.7 0.0 0.024 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KND91546.1 - 4.9e-06 26.5 1.5 0.062 13.0 0.0 3.8 4 0 0 4 4 3 2 AAA ATPase domain Dynamin_N PF00350.23 KND91546.1 - 5.9e-06 26.4 0.1 0.00091 19.3 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 KND91546.1 - 7.8e-06 26.5 0.1 0.21 12.2 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 KND91546.1 - 2e-05 24.8 0.1 0.53 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KND91546.1 - 2.1e-05 24.9 0.0 0.51 10.8 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KND91546.1 - 3.2e-05 23.7 0.1 0.066 12.9 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KND91546.1 - 3.2e-05 23.0 0.1 0.21 10.5 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB HEAT PF02985.22 KND91546.1 - 5.3e-05 23.1 0.5 1.8 9.1 0.1 4.2 4 0 0 4 4 3 1 HEAT repeat AAA_16 PF13191.6 KND91546.1 - 5.8e-05 23.5 0.0 0.32 11.4 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KND91546.1 - 7e-05 23.2 0.0 0.94 9.9 0.0 3.2 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 KND91546.1 - 0.00016 21.3 0.0 0.14 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND91546.1 - 0.00036 20.5 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KND91546.1 - 0.00043 20.1 0.0 0.61 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KND91546.1 - 0.00044 19.5 0.1 1.3 8.1 0.0 2.9 3 0 0 3 3 3 2 G-protein alpha subunit AAA_30 PF13604.6 KND91546.1 - 0.0012 18.6 0.0 3.1 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KND91546.1 - 0.0015 18.7 1.1 0.99 9.4 0.0 3.7 4 0 0 4 4 4 1 Helicase HerA, central domain cobW PF02492.19 KND91546.1 - 0.0017 18.0 0.2 3.2 7.3 0.0 3.6 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KND91546.1 - 0.0019 18.3 0.0 4.3 7.4 0.0 3.2 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 KND91546.1 - 0.0022 17.9 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Septin PF00735.18 KND91546.1 - 0.0025 17.2 0.4 1.9 7.7 0.0 3.2 3 0 0 3 3 3 1 Septin SbcCD_C PF13558.6 KND91546.1 - 0.0038 17.4 0.0 1.8 8.9 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 KND91546.1 - 0.0049 16.7 0.1 6.4 6.5 0.0 3.3 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 KND91546.1 - 0.0053 16.0 0.5 0.38 9.9 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain ATPase_2 PF01637.18 KND91546.1 - 0.006 16.5 0.1 3.8 7.4 0.0 3.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Roc PF08477.13 KND91546.1 - 0.0083 16.3 0.0 7.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 KND91546.1 - 0.0085 15.9 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family CLP1_P PF16575.5 KND91546.1 - 0.014 15.2 0.0 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 KND91546.1 - 0.017 14.6 0.0 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 KND91546.1 - 0.018 14.8 0.0 5.5 6.7 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 KND91546.1 - 0.027 14.1 0.0 8.3 6.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ParcG PF10274.9 KND91546.1 - 0.033 14.3 0.3 0.67 10.0 0.0 2.7 1 1 2 3 3 3 0 Parkin co-regulated protein T2SSE PF00437.20 KND91546.1 - 0.033 13.2 0.2 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KND91546.1 - 0.06 13.1 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 KND91546.1 - 0.065 12.5 0.1 14 4.9 0.0 3.0 3 0 0 3 3 2 0 Zeta toxin AAA_25 PF13481.6 KND91546.1 - 0.067 12.8 0.0 7.7 6.0 0.0 3.1 2 1 1 3 3 2 0 AAA domain Transglut_prok PF09017.10 KND91546.1 - 0.071 12.4 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Microbial transglutaminase NTPase_1 PF03266.15 KND91546.1 - 0.077 12.9 0.0 18 5.2 0.0 2.8 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 KND91546.1 - 0.078 12.9 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 KND91546.1 - 0.089 12.2 0.0 5.2 6.4 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 KND91546.1 - 0.1 11.7 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) YoeB_toxin PF06769.14 KND91546.1 - 0.13 12.3 0.9 0.87 9.7 0.3 2.3 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system FeoB_N PF02421.18 KND91546.1 - 0.14 11.7 0.3 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 KND91546.1 - 0.14 12.1 0.0 29 4.7 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MMS19_C PF12460.8 KND91546.1 - 0.14 11.2 0.2 4.3 6.3 0.0 2.8 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal AAA_13 PF13166.6 KND91546.1 - 0.96 8.0 9.5 2.7 6.5 0.0 4.0 5 0 0 5 5 4 0 AAA domain RNase_H2_suC PF08615.11 KND91547.1 - 4.8e-22 78.7 0.0 6.9e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_2 PF07719.17 KND91548.1 - 2.2e-12 46.0 10.1 0.00016 21.5 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND91548.1 - 1.9e-11 43.2 6.0 0.0029 17.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND91548.1 - 1.7e-09 37.8 8.9 0.002 18.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND91548.1 - 3.2e-07 30.0 8.0 0.015 15.5 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND91548.1 - 2.4e-06 28.1 0.0 2.4e-06 28.1 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND91548.1 - 2.8e-06 27.8 5.1 0.012 16.1 0.0 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND91548.1 - 5.1e-05 22.9 4.5 0.011 15.3 0.0 4.9 4 1 1 5 5 5 1 TPR repeat ANAPC3 PF12895.7 KND91548.1 - 0.0014 18.8 3.2 0.023 14.9 0.1 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KND91548.1 - 0.0053 17.5 17.6 0.024 15.4 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 KND91548.1 - 0.0062 16.7 0.0 0.0062 16.7 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat SNAP PF14938.6 KND91548.1 - 0.0064 15.9 2.3 0.26 10.7 0.3 2.4 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KND91548.1 - 0.0093 15.9 5.1 1.8 8.8 0.0 4.6 5 0 0 5 5 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 KND91548.1 - 0.035 13.5 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR RPN7 PF10602.9 KND91548.1 - 0.086 12.5 0.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Coatomer_WDAD PF04053.14 KND91548.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region TPR_6 PF13174.6 KND91548.1 - 0.17 12.6 6.0 24 5.8 0.3 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat AA_permease PF00324.21 KND91549.1 - 7.1e-94 315.1 31.1 8.2e-94 314.9 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND91549.1 - 3.3e-28 98.7 34.6 4.2e-28 98.3 34.6 1.1 1 0 0 1 1 1 1 Amino acid permease GYF PF02213.16 KND91550.1 - 1.7e-17 62.8 1.8 2.2e-17 62.5 0.2 2.1 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 KND91550.1 - 0.01 15.6 0.0 0.045 13.6 0.0 2.2 1 0 0 1 1 1 0 GYF domain 2 DUF572 PF04502.13 KND91551.1 - 0.16 11.6 2.4 0.11 12.1 0.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Acyltransferase PF01553.21 KND91552.1 - 8.5e-18 64.3 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 KND91553.1 - 1.2e-28 98.9 0.1 1.8e-28 98.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Aldedh PF00171.22 KND91554.1 - 3.4e-177 589.6 6.6 1.2e-176 587.8 6.6 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Pantoate_ligase PF02569.15 KND91555.1 - 1.5e-71 240.8 0.0 4.1e-70 236.0 0.0 2.1 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase MFS_1 PF07690.16 KND91555.1 - 2.7e-34 118.7 54.5 2.7e-34 118.7 54.5 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91555.1 - 1e-07 31.2 7.7 1e-07 31.2 7.7 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3377 PF11857.8 KND91555.1 - 0.0041 17.0 0.1 0.036 14.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3377) RhodobacterPufX PF11511.8 KND91555.1 - 0.48 10.1 3.2 3.7 7.2 0.3 3.4 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Alpha_kinase PF02816.18 KND91556.1 - 1.9e-48 165.1 0.0 3e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 KND91556.1 - 4e-12 46.7 0.0 1.6e-11 44.8 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KND91556.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Reprolysin_5 PF13688.6 KND91556.1 - 0.12 12.5 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Metallo-peptidase family M12 p450 PF00067.22 KND91557.1 - 2.7e-72 244.0 0.0 3.4e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.21 KND91558.1 - 8.1e-37 126.8 0.0 6.5e-17 61.3 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 KND91558.1 - 1.9e-14 54.0 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain OrsD PF12013.8 KND91559.1 - 1.5e-12 48.0 1.2 9.7e-12 45.3 0.6 2.0 1 1 1 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 KND91559.1 - 0.00021 21.3 4.7 0.47 10.5 3.0 2.4 2 0 0 2 2 2 2 BED zinc finger zf_C2H2_ZHX PF18387.1 KND91559.1 - 0.0069 16.0 0.5 1 9.0 0.2 2.2 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 KND91559.1 - 0.087 13.2 2.6 3.9 7.9 2.9 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 KND91559.1 - 0.087 13.0 0.3 0.52 10.5 0.2 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) BIR PF00653.21 KND91559.1 - 0.12 13.1 0.1 0.34 11.6 0.0 1.8 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_4 PF13894.6 KND91559.1 - 0.13 13.1 7.1 1.2 10.2 2.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KND91559.1 - 0.17 11.7 9.4 0.14 12.0 5.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KND91559.1 - 0.98 9.2 7.9 0.54 10.1 4.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 KND91559.1 - 3.2 8.4 6.8 3 8.5 2.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ank_2 PF12796.7 KND91560.1 - 1.7e-15 57.4 24.7 0.0016 19.0 0.1 11.9 9 3 3 13 13 13 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND91560.1 - 1.5e-06 28.0 10.9 13 6.7 0.0 11.3 13 0 0 13 13 13 2 Ankyrin repeat Ank_4 PF13637.6 KND91560.1 - 4.1e-06 27.2 10.8 3.4 8.4 0.0 9.4 10 1 1 11 11 11 2 Ankyrin repeats (many copies) HEAT_2 PF13646.6 KND91560.1 - 0.02 15.3 0.3 0.46 10.9 0.1 3.6 2 0 0 2 2 2 0 HEAT repeats Ank_5 PF13857.6 KND91560.1 - 0.089 13.1 8.4 32 5.0 0.0 6.7 8 0 0 8 8 8 0 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.21 KND91563.1 - 1.6e-26 93.4 0.0 3.6e-26 92.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND91563.1 - 0.039 12.5 0.0 0.26 9.8 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme BATS PF06968.13 KND91564.1 - 1.6e-22 79.4 0.1 3.9e-22 78.2 0.1 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KND91564.1 - 5.9e-14 52.8 0.1 9.1e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily F-box PF00646.33 KND91566.1 - 0.022 14.6 0.2 0.13 12.2 0.3 2.3 2 0 0 2 2 2 0 F-box domain TFIIIC_sub6 PF10419.9 KND91567.1 - 1.4e-27 95.4 0.1 2.3e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Vps62 PF06101.11 KND91568.1 - 1.3e-11 43.5 0.2 2.8e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Trimer_CC PF08954.11 KND91569.1 - 0.14 11.7 0.9 2.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Trimerisation motif FlxA PF14282.6 KND91569.1 - 3.5 7.7 5.7 1.1 9.3 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Ribosomal_L16 PF00252.18 KND91571.1 - 1.6e-44 151.1 0.0 2e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 KND91572.1 - 6.5e-24 83.5 0.0 7.4e-24 83.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ComP_DUS PF16732.5 KND91573.1 - 0.24 12.3 3.0 2 9.3 0.5 2.6 2 0 0 2 2 2 0 Type IV minor pilin ComP, DNA uptake sequence receptor LtuB PF17455.2 KND91573.1 - 0.54 10.9 1.9 0.83 10.3 0.3 2.1 1 1 1 2 2 2 0 Late transcription unit B CorA PF01544.18 KND91573.1 - 1.1 8.6 8.9 2.1 7.6 8.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.13 KND91573.1 - 2.4 7.3 8.9 5.8 6.1 8.9 1.7 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 KND91573.1 - 4.1 6.6 23.5 9.8 5.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ALMT PF11744.8 KND91573.1 - 4.8 5.9 7.1 8 5.2 7.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4200 PF13863.6 KND91573.1 - 9 6.7 40.0 1.7 9.0 0.7 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 KND91573.1 - 9 6.5 19.3 3.1 8.0 9.8 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4139 PF13598.6 KND91574.1 - 1.9e-34 119.2 0.0 5.7e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KND91574.1 - 7.7e-28 96.8 0.1 7.7e-28 96.8 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) CARDB PF07705.11 KND91574.1 - 0.026 14.8 0.1 3.2 8.1 0.1 3.2 3 0 0 3 3 3 0 CARDB Methyltransf_10 PF05971.12 KND91575.1 - 4.6e-62 210.0 0.0 6.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KND91575.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KND91575.1 - 0.018 15.7 0.0 0.1 13.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 KND91575.1 - 0.021 14.8 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KND91575.1 - 0.022 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KND91575.1 - 0.15 12.7 0.0 0.37 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 KND91575.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Arf PF00025.21 KND91576.1 - 1.9e-26 92.6 0.0 3.4e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF218 PF02698.17 KND91576.1 - 1.9e-23 82.9 0.0 1.4e-22 80.1 0.0 2.5 4 0 0 4 4 4 1 DUF218 domain Roc PF08477.13 KND91576.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KND91576.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KND91576.1 - 0.0038 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Iso_dh PF00180.20 KND91578.1 - 1.1e-113 380.0 0.0 1.3e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF745 PF05335.13 KND91578.1 - 0.19 11.4 1.8 0.39 10.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Pkinase_fungal PF17667.1 KND91579.1 - 5.8e-35 120.8 0.1 8.2e-35 120.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Cation_ATPase_C PF00689.21 KND91580.1 - 3.2e-16 59.6 0.3 3.2e-16 59.6 0.3 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus APH PF01636.23 KND91581.1 - 1.8e-13 51.0 0.0 2.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND91581.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Beta-lactamase PF00144.24 KND91584.1 - 0.01 15.1 1.9 0.8 8.9 0.4 3.0 2 1 0 2 2 2 0 Beta-lactamase APH PF01636.23 KND91585.1 - 1e-08 35.4 0.0 1.6e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND91585.1 - 0.12 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain GATase_5 PF13507.6 KND91586.1 - 1.2e-95 319.5 0.0 1.8e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KND91586.1 - 1.3e-31 109.9 1.2 3.5e-23 82.5 0.0 2.6 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KND91586.1 - 2.7e-25 88.6 0.0 4.8e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KND91586.1 - 1.2e-22 80.2 0.0 2.9e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain HD PF01966.22 KND91587.1 - 2.9e-05 24.3 0.1 5.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 HD domain F-box-like PF12937.7 KND91588.1 - 0.00028 20.7 0.2 0.00089 19.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND91588.1 - 0.00045 20.0 0.1 0.00086 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain Kp4 PF09044.10 KND91589.1 - 0.01 15.9 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Kp4 Esterase_phd PF10503.9 KND91590.1 - 8.3e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 KND91590.1 - 4.3e-06 26.6 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KND91590.1 - 0.0025 17.6 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KND91590.1 - 0.01 15.3 0.1 0.026 14.0 0.1 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 KND91590.1 - 0.075 11.7 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) EF-hand_4 PF12763.7 KND91592.1 - 2.7e-05 24.1 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Myb_DNA-bind_6 PF13921.6 KND91593.1 - 2.3e-14 53.4 0.4 6.6e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KND91593.1 - 2.4e-12 46.8 0.3 5.6e-05 23.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain ApbA_C PF08546.11 KND91594.1 - 9.5e-12 45.2 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Imm12 PF15560.6 KND91595.1 - 0.081 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 12 MFS_1 PF07690.16 KND91596.1 - 1.8e-45 155.4 29.8 9.7e-42 143.1 12.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91596.1 - 4.9e-10 38.9 23.4 1.2e-08 34.3 10.5 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KND91596.1 - 6e-05 21.7 7.7 9.4e-05 21.0 7.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transgly_assoc PF04226.13 KND91596.1 - 2.7 8.3 7.8 46 4.4 0.2 3.5 2 0 0 2 2 2 0 Transglycosylase associated protein OATP PF03137.20 KND91596.1 - 4.2 5.5 6.2 5 5.3 2.1 2.5 1 1 1 2 2 1 0 Organic Anion Transporter Polypeptide (OATP) family MAP65_ASE1 PF03999.12 KND91597.1 - 9.1e-75 252.5 6.1 1.9e-74 251.5 5.8 1.4 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) XhlA PF10779.9 KND91597.1 - 0.098 12.9 0.5 0.42 10.8 0.5 2.1 1 0 0 1 1 1 0 Haemolysin XhlA Cnn_1N PF07989.11 KND91597.1 - 3.1 8.0 7.3 7.5 6.8 0.1 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 SKA2 PF16740.5 KND91597.1 - 6.6 6.6 7.4 3 7.7 0.1 3.6 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 Osmo_CC PF08946.10 KND91597.1 - 7.4 6.9 6.7 43 4.5 0.2 3.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil PNP_UDP_1 PF01048.20 KND91598.1 - 0.00017 20.9 0.1 0.0002 20.7 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ac76 PF05814.11 KND91598.1 - 0.07 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) p450 PF00067.22 KND91599.1 - 2.2e-49 168.5 0.0 1e-37 130.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Pex16 PF08610.10 KND91600.1 - 3.8e-141 469.9 0.0 4.9e-141 469.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Brr6_like_C_C PF10104.9 KND91601.1 - 5e-37 126.7 2.0 5e-37 126.7 2.0 1.6 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain Fungal_trans PF04082.18 KND91601.1 - 1e-17 64.1 1.3 1.1e-17 63.9 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91601.1 - 5.9e-08 32.7 10.8 5.9e-08 32.7 10.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Piwi PF02171.17 KND91602.1 - 1.6e-67 227.9 0.0 2.5e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KND91602.1 - 3.9e-21 76.1 0.1 6.7e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KND91602.1 - 2.8e-13 49.3 0.1 7.4e-13 48.0 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KND91602.1 - 2.6e-12 46.9 0.1 9.3e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 KND91602.1 - 8.5e-11 41.8 0.0 3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 PAZ domain zf-met PF12874.7 KND91603.1 - 0.023 15.1 4.4 0.93 10.0 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KND91603.1 - 0.13 13.1 19.2 0.078 13.8 1.6 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KND91603.1 - 2.9 8.5 17.3 0.14 12.6 1.1 3.4 2 1 1 3 3 3 0 Zinc finger, C2H2 type ZZ PF00569.17 KND91603.1 - 3.3 7.6 8.2 0.61 9.9 3.4 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type Pkinase PF00069.25 KND91605.1 - 2.7e-40 138.4 0.2 8.7e-23 81.0 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND91605.1 - 7.6e-14 51.6 0.3 6e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Med26 PF08711.11 KND91606.1 - 9.5e-11 41.6 0.0 2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TOC159_MAD PF11886.8 KND91607.1 - 0.0025 16.8 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain Cyto_heme_lyase PF01265.17 KND91608.1 - 7.1e-41 140.7 13.4 9.4e-39 133.7 13.4 2.8 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_L28e PF01778.17 KND91609.1 - 1.1e-35 122.8 2.1 1.4e-35 122.5 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2015 PF09435.10 KND91610.1 - 2.2e-47 159.5 0.0 2.6e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Glyco_hydro_108 PF05838.12 KND91610.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Ldh_1_C PF02866.18 KND91611.1 - 7.2e-45 152.9 0.0 1.2e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KND91611.1 - 1.4e-41 141.9 0.2 2e-41 141.4 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KND91611.1 - 0.00079 18.5 0.0 0.001 18.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KND91611.1 - 0.03 14.7 0.0 0.069 13.6 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KND91611.1 - 0.11 11.8 0.1 1.4 8.2 0.1 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_72 PF03198.14 KND91612.1 - 5.2e-125 416.9 3.9 6.9e-125 416.5 3.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KND91612.1 - 8.4e-07 28.7 0.5 5.1e-06 26.1 0.5 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aa_trans PF01490.18 KND91614.1 - 4e-61 206.9 26.2 5.4e-61 206.5 26.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_hydroxylase PF04116.13 KND91615.1 - 2.5e-24 86.1 17.3 2.5e-24 86.1 17.3 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pex14_N PF04695.13 KND91615.1 - 0.25 12.0 2.2 0.41 11.3 2.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 KND91616.1 - 6e-59 194.6 13.5 2.7e-08 34.3 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KND91616.1 - 2.5e-17 62.9 9.4 4.5e-17 62.1 9.4 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KND91616.1 - 1.8e-15 57.0 0.0 0.00042 20.6 0.0 5.4 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND91616.1 - 1.6e-06 27.7 0.0 0.34 10.2 0.0 4.9 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KND91616.1 - 3.5e-06 26.2 0.4 0.68 8.8 0.0 5.0 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KND91616.1 - 0.018 13.7 1.2 0.7 8.5 0.0 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KND91616.1 - 0.019 14.3 0.1 10 5.4 0.0 3.1 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 KND91616.1 - 0.033 12.7 0.4 1.3 7.4 0.1 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Golgin_A5 PF09787.9 KND91616.1 - 0.055 12.9 3.6 0.081 12.4 3.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 AIP3 PF03915.13 KND91616.1 - 0.11 11.6 0.4 0.15 11.1 0.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Nucleoporin_N PF08801.11 KND91616.1 - 0.13 11.0 0.1 15 4.2 0.1 3.2 2 1 1 3 3 3 0 Nup133 N terminal like SHE3 PF17078.5 KND91616.1 - 0.17 11.6 2.5 0.25 11.0 2.5 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 MMS1_N PF10433.9 KND91616.1 - 0.18 10.4 0.0 1.1 7.8 0.0 1.9 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Tektin PF03148.14 KND91616.1 - 0.34 9.6 4.0 0.48 9.1 4.0 1.1 1 0 0 1 1 1 0 Tektin family TPX2 PF06886.11 KND91616.1 - 4.1 7.7 5.8 25 5.2 5.8 1.9 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Pkinase PF00069.25 KND91617.1 - 3.9e-53 180.5 0.0 5.7e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91617.1 - 9.6e-34 116.8 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND91617.1 - 1e-13 51.2 0.0 6.9e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KND91617.1 - 0.0069 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND91617.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CPBP PF02517.16 KND91618.1 - 4e-15 55.9 8.1 4e-15 55.9 8.1 2.3 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease Serglycin PF04360.12 KND91618.1 - 0.00065 19.7 0.3 0.00099 19.1 0.3 1.4 1 0 0 1 1 1 1 Serglycin Synaptobrevin PF00957.21 KND91619.1 - 0.1 12.4 1.0 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Synaptobrevin MBOAT PF03062.19 KND91620.1 - 1.6e-50 172.4 0.5 1.6e-50 172.4 0.5 2.0 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family UAA PF08449.11 KND91621.1 - 3.1e-08 33.2 17.1 4.1e-08 32.8 17.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KND91621.1 - 0.0021 18.2 7.4 0.0021 18.2 7.4 2.2 2 0 0 2 2 2 1 EamA-like transporter family Gti1_Pac2 PF09729.9 KND91622.1 - 3.6e-60 203.1 0.0 4.7e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 KND91623.1 - 7.2e-15 55.5 0.5 7.2e-15 55.5 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 KND91624.1 - 2.6e-154 514.1 0.0 3.5e-154 513.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Sec1 PF00995.23 KND91624.1 - 2.9e-128 429.7 0.0 3.6e-128 429.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family GIDA_assoc PF13932.6 KND91624.1 - 8.2e-65 218.9 0.2 1.7e-64 217.8 0.0 1.6 2 0 0 2 2 2 1 GidA associated domain FAD_oxidored PF12831.7 KND91624.1 - 3.7e-06 26.6 0.2 7.1e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND91624.1 - 6.3e-06 25.6 0.1 1.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND91624.1 - 0.0013 17.9 2.9 0.0013 17.9 2.9 1.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 KND91624.1 - 0.0023 17.3 0.1 0.0056 16.0 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KND91624.1 - 0.1 13.1 0.1 0.49 11.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND91624.1 - 0.15 10.7 5.9 0.17 10.6 1.4 2.7 3 0 0 3 3 3 0 HI0933-like protein MMM1 PF10296.9 KND91625.1 - 1.9e-141 470.9 0.3 6e-140 466.0 0.3 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Snf7 PF03357.21 KND91626.1 - 1.1e-19 70.6 13.9 1.6e-19 70.1 13.9 1.2 1 0 0 1 1 1 1 Snf7 PVL_ORF50 PF07768.11 KND91626.1 - 3.4 8.0 5.9 0.67 10.3 1.3 2.1 2 0 0 2 2 2 0 PVL ORF-50-like family CorA PF01544.18 KND91626.1 - 3.7 6.8 11.4 4.2 6.6 6.0 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein End3 PF12761.7 KND91626.1 - 4.4 7.4 16.3 6.8 6.8 1.9 2.4 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 zf-C3HC4_2 PF13923.6 KND91627.1 - 8.6e-13 47.9 9.3 8.6e-13 47.9 9.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND91627.1 - 8e-09 35.2 9.2 8e-09 35.2 9.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND91627.1 - 2.8e-08 33.7 7.1 2.8e-08 33.7 7.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KND91627.1 - 5.1e-08 32.7 6.8 5.1e-08 32.7 6.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND91627.1 - 4.4e-07 29.8 8.8 4.4e-07 29.8 8.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND91627.1 - 1.9e-06 28.1 8.8 1.9e-06 28.1 8.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 KND91627.1 - 4.4e-06 26.5 2.6 4.4e-06 26.5 2.6 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 KND91627.1 - 7.1e-06 25.8 11.6 0.00011 21.9 7.8 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KND91627.1 - 8.9e-06 25.9 3.5 8.9e-06 25.9 3.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KND91627.1 - 2.2e-05 24.5 9.1 2.2e-05 24.5 9.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.13 KND91627.1 - 0.0015 18.4 1.7 0.0015 18.4 1.7 1.8 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 KND91627.1 - 0.0016 18.2 2.0 0.0016 18.2 2.0 2.7 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain SAP PF02037.27 KND91627.1 - 0.0018 18.0 1.4 0.0027 17.4 0.3 2.0 2 0 0 2 2 2 1 SAP domain zf-RING_10 PF16685.5 KND91627.1 - 0.0071 16.5 6.1 0.016 15.3 6.1 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 KND91627.1 - 0.021 14.7 2.7 4.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif Sgf11 PF08209.11 KND91627.1 - 0.057 13.0 0.1 0.23 11.1 0.1 2.1 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) U-box PF04564.15 KND91627.1 - 0.072 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-WRNIP1_ubi PF18279.1 KND91627.1 - 0.18 12.5 0.3 0.18 12.5 0.3 2.9 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zinc-ribbons_6 PF07191.12 KND91627.1 - 0.32 11.0 9.1 1.6 8.8 4.3 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-ANAPC11 PF12861.7 KND91627.1 - 0.54 10.3 4.9 0.094 12.8 0.9 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATP-synt_DE PF00401.20 KND91627.1 - 0.67 10.3 3.8 0.3 11.4 0.8 2.1 2 0 0 2 2 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain zf-P11 PF03854.14 KND91627.1 - 1.3 8.7 11.2 0.044 13.4 5.0 1.7 2 0 0 2 2 1 0 P-11 zinc finger Glyoxalase PF00903.25 KND91629.1 - 0.014 15.6 0.1 0.059 13.6 0.0 1.8 1 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Taeniidae_ag PF05596.11 KND91629.1 - 0.14 12.1 0.0 1.3 9.1 0.0 2.2 2 1 0 2 2 2 0 Taeniidae antigen Methyltransf_24 PF13578.6 KND91630.1 - 1.2e-07 32.7 0.0 3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_4 PF01565.23 KND91631.1 - 3e-24 85.4 0.9 5.6e-24 84.4 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND91631.1 - 4.1e-12 46.0 0.0 7.8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_S10 PF00450.22 KND91633.1 - 2.9e-127 425.6 0.8 3.7e-127 425.2 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KND91633.1 - 0.11 13.0 0.8 0.23 12.0 0.2 1.8 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide K_oxygenase PF13434.6 KND91634.1 - 3.8e-14 52.6 0.0 1.6e-08 34.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KND91634.1 - 4.6e-09 35.9 0.0 0.00049 19.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND91634.1 - 7.1e-07 28.8 0.0 0.046 13.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND91634.1 - 3.2e-05 23.7 0.6 0.014 15.0 1.7 3.2 1 1 2 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND91634.1 - 4.5e-05 22.9 0.5 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 KND91634.1 - 0.00071 18.4 0.0 0.2 10.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KND91634.1 - 0.00096 19.2 0.1 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND91634.1 - 0.0026 18.0 0.2 0.024 14.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND91634.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KND91634.1 - 0.041 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KND91634.1 - 0.042 12.9 0.0 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Peptidase_M20 PF01546.28 KND91635.1 - 4.8e-20 72.1 0.0 9.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND91635.1 - 7.7e-05 22.6 0.4 0.0002 21.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain SKG6 PF08693.10 KND91635.1 - 0.043 13.2 2.1 0.098 12.1 2.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 KND91635.1 - 5.8 7.5 19.0 0.19 12.3 11.6 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF3638 PF12340.8 KND91636.1 - 5.5e-92 307.2 0.1 7.4e-92 306.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF815 PF05673.13 KND91636.1 - 0.043 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_flagellin PF01917.16 KND91636.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaebacterial flagellin Chitin_synth_1 PF01644.17 KND91637.1 - 1.6e-77 259.0 0.0 2.8e-77 258.3 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KND91637.1 - 9e-28 96.0 0.3 2e-27 94.9 0.3 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KND91637.1 - 2.3e-24 85.9 1.7 3e-21 75.7 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KND91637.1 - 4.6e-07 29.9 3.9 2.4e-06 27.6 3.9 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Ribosomal_S12 PF17487.2 KND91637.1 - 0.093 13.5 6.5 0.68 10.7 1.2 2.9 2 0 0 2 2 2 0 Ribosomal protein S12 Sugar_tr PF00083.24 KND91638.1 - 2e-92 310.4 26.3 2.6e-92 310.1 26.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91638.1 - 4.7e-21 75.1 19.0 4.7e-21 75.1 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kei1 PF08552.11 KND91639.1 - 1.8e-55 187.8 10.5 6.2e-54 182.8 10.5 2.1 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Na_Ca_ex PF01699.24 KND91639.1 - 0.38 10.7 8.8 0.26 11.3 5.1 2.0 2 0 0 2 2 2 0 Sodium/calcium exchanger protein SPC12 PF06645.13 KND91639.1 - 7.3 6.8 8.1 0.36 11.0 1.9 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NIR_SIR PF01077.22 KND91640.1 - 5.3e-51 172.3 0.1 2e-47 160.7 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KND91640.1 - 8.8e-31 105.6 0.0 3.3e-15 55.7 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KND91640.1 - 2.1e-28 99.3 0.0 4.9e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 KND91640.1 - 1.4e-05 25.0 0.5 2.9e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PFOR_II PF17147.4 KND91640.1 - 2.3e-05 24.6 0.0 6.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Nop53 PF07767.11 KND91641.1 - 1.6e-108 363.6 32.5 1.9e-108 363.4 32.5 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BAF1_ABF1 PF04684.13 KND91641.1 - 0.68 8.9 11.8 1.3 8.0 11.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ras PF00071.22 KND91642.1 - 7e-60 201.3 0.4 9.1e-60 200.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND91642.1 - 1.5e-37 128.5 0.1 2.5e-37 127.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND91642.1 - 2.1e-18 66.4 0.3 2.6e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND91642.1 - 1.8e-06 27.7 0.1 1.2e-05 24.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KND91642.1 - 1e-05 25.1 0.1 1.5e-05 24.5 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KND91642.1 - 2e-05 24.7 0.0 3.6e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND91642.1 - 2.6e-05 23.7 0.5 3.4e-05 23.3 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KND91642.1 - 0.00018 21.5 0.1 0.11 12.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 KND91642.1 - 0.0025 17.6 0.2 0.0074 16.1 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FlgH PF02107.16 KND91642.1 - 0.03 13.9 1.0 0.041 13.5 1.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 KND91642.1 - 0.054 14.1 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 KND91642.1 - 0.062 13.5 0.0 0.89 9.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_28 PF13521.6 KND91642.1 - 0.15 12.3 0.1 5 7.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 KND91643.1 - 4.6e-58 196.2 0.0 6.5e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KND91643.1 - 1.9e-40 138.5 0.0 2.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_33 PF13671.6 KND91643.1 - 2.1e-06 28.0 0.2 1.8e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND91643.1 - 6.1e-06 26.8 0.0 2.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 KND91643.1 - 9.1e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KND91643.1 - 2.4e-05 24.8 1.4 0.15 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 KND91643.1 - 0.00031 20.1 0.0 0.00076 18.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 KND91643.1 - 0.0066 17.0 0.0 0.021 15.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KND91643.1 - 0.0093 15.2 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KND91643.1 - 0.015 15.6 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KND91643.1 - 0.033 13.9 0.1 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin PF02224.18 KND91643.1 - 0.04 13.7 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DUF87 PF01935.17 KND91643.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KND91643.1 - 0.064 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND91643.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 KND91643.1 - 0.15 12.4 0.0 0.53 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KND91643.1 - 0.19 12.1 0.0 0.58 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Pyr_redox_2 PF07992.14 KND91644.1 - 7.2e-41 140.3 0.0 1.1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND91644.1 - 2.6e-14 53.5 0.0 1.6e-10 41.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KND91644.1 - 8.2e-07 28.1 0.3 1.7e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KND91644.1 - 2.4e-05 23.9 0.5 7.3e-05 22.4 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KND91644.1 - 0.00018 21.9 0.1 0.0005 20.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KND91644.1 - 0.00049 19.5 1.1 0.001 18.4 1.1 1.5 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 KND91644.1 - 0.026 13.8 0.0 1.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase bVLRF1 PF18826.1 KND91644.1 - 0.099 12.5 0.2 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor ETC_C1_NDUFA4 PF04800.12 KND91645.1 - 2.9e-35 120.4 1.6 3.9e-35 120.0 1.6 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region MucBP_2 PF17965.1 KND91645.1 - 0.17 12.5 0.1 0.27 11.8 0.1 1.3 1 0 0 1 1 1 0 Mucin binding domain CLTH PF10607.9 KND91646.1 - 7e-32 110.4 0.1 8.8e-32 110.0 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KND91646.1 - 0.14 12.1 0.2 0.41 10.7 0.2 1.9 1 0 0 1 1 1 0 LisH Macro PF01661.21 KND91647.1 - 1e-39 135.3 0.0 1.3e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Macro domain Ion_trans PF00520.31 KND91648.1 - 1.6e-05 24.3 24.6 0.00024 20.4 24.6 2.2 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KND91648.1 - 6.9e-05 21.7 18.2 0.0016 17.2 18.0 2.3 1 1 0 1 1 1 1 Polycystin cation channel Kinesin_assoc PF16183.5 KND91648.1 - 0.22 11.6 0.9 0.4 10.8 0.4 1.6 2 0 0 2 2 2 0 Kinesin-associated RP-C_C PF11800.8 KND91648.1 - 0.65 10.0 2.9 0.69 10.0 1.0 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region tRNA-synt_1c PF00749.21 KND91649.1 - 1e-101 340.0 0.1 1.8e-101 339.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KND91649.1 - 3.2e-30 105.3 0.0 2.3e-29 102.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Rib_5-P_isom_A PF06026.14 KND91650.1 - 9.5e-45 152.3 0.0 2.2e-44 151.1 0.0 1.6 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DUF1308 PF07000.11 KND91652.1 - 3.5e-07 30.3 0.0 8.5e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1308) DUF2285 PF10074.9 KND91652.1 - 0.03 15.0 2.8 2.3 8.9 0.0 3.7 4 1 1 5 5 5 0 Uncharacterized conserved protein (DUF2285) AAA PF00004.29 KND91654.1 - 1.4e-15 57.9 0.0 3.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND91654.1 - 0.0059 16.9 2.4 0.11 12.8 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KND91654.1 - 0.0097 16.3 0.2 0.049 14.0 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KND91654.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KND91654.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND91654.1 - 0.08 12.7 0.0 0.08 12.7 0.0 2.9 3 1 0 3 3 3 0 AAA domain Fungal_trans PF04082.18 KND91656.1 - 7.6e-12 44.8 0.0 1.1e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91656.1 - 6.9e-09 35.7 9.6 1.4e-08 34.7 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain POB3_N PF17292.2 KND91657.1 - 2.2e-30 104.9 0.4 1.5e-28 99.0 0.1 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 KND91657.1 - 2e-29 101.3 0.1 1.6e-28 98.4 0.0 2.6 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KND91657.1 - 3.6e-23 81.8 0.0 2e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Lipase_3 PF01764.25 KND91658.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KND91658.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 KND91658.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MCR_beta PF02241.18 KND91658.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain SLBP_RNA_bind PF15247.6 KND91658.1 - 0.7 10.1 2.1 0.55 10.4 0.3 1.7 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain YL1 PF05764.13 KND91659.1 - 1.1e-73 248.4 27.6 1.1e-73 248.4 27.6 4.2 4 0 0 4 4 4 2 YL1 nuclear protein YL1_C PF08265.11 KND91659.1 - 1.3e-12 47.2 0.4 2.3e-12 46.4 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Troponin-I_N PF11636.8 KND91660.1 - 4.3 7.4 9.0 0.12 12.3 1.4 2.5 2 0 0 2 2 2 0 Troponin I residues 1-32 FA_hydroxylase PF04116.13 KND91661.1 - 4e-24 85.4 12.1 4e-24 85.4 12.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.17 KND91662.1 - 4.7e-68 228.7 0.6 5.3e-68 228.6 0.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AIM3 PF17096.5 KND91663.1 - 0.00036 21.4 0.1 0.00036 21.4 0.1 4.3 4 2 0 4 4 4 1 Altered inheritance of mitochondria protein 3 Mis12 PF05859.12 KND91664.1 - 1.4e-42 145.0 0.0 2.3e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein PPR_2 PF13041.6 KND91665.1 - 6.1e-17 61.5 0.0 0.0063 16.7 0.0 7.1 6 2 3 9 9 9 4 PPR repeat family PPR_3 PF13812.6 KND91665.1 - 5.2e-13 48.9 0.0 6.6e-06 26.1 0.0 6.0 5 1 3 8 8 8 4 Pentatricopeptide repeat domain PPR PF01535.20 KND91665.1 - 3.8e-07 29.9 0.0 0.87 10.0 0.5 5.7 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 KND91665.1 - 3e-06 26.7 0.4 0.0038 16.6 0.1 3.0 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KND91665.1 - 6.4e-05 22.6 0.0 0.21 11.3 0.0 3.7 3 0 0 3 3 3 1 PPR repeat RPM2 PF08579.11 KND91665.1 - 0.1 13.0 0.0 2 8.8 0.0 2.9 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Glyoxalase PF00903.25 KND91665.1 - 0.12 12.5 0.1 5.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_14 PF13428.6 KND91665.1 - 0.15 13.0 0.3 0.15 13.0 0.3 6.8 7 1 1 8 8 8 0 Tetratricopeptide repeat GST_C_2 PF13410.6 KND91666.1 - 3.2e-07 30.3 0.1 7.3e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KND91666.1 - 5.7e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KND91666.1 - 8.8e-07 29.2 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KND91666.1 - 2e-05 24.8 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KND91666.1 - 0.0001 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND91666.1 - 0.00033 20.8 0.0 0.00066 19.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2890 PF11081.8 KND91667.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pkinase PF00069.25 KND91668.1 - 3.8e-26 92.0 0.0 1.2e-25 90.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91668.1 - 9.6e-05 21.8 0.4 0.0028 17.0 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KND91668.1 - 0.065 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.18 KND91670.1 - 1.1e-35 121.8 0.0 2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KND91670.1 - 1.2e-29 102.6 0.8 2.1e-29 101.8 0.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 KND91671.1 - 7.6e-16 58.5 0.0 1.3e-15 57.8 0.0 1.4 2 0 0 2 2 2 1 GINS complex protein APH PF01636.23 KND91673.1 - 2.2e-10 40.9 0.1 3e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cnn_1N PF07989.11 KND91674.1 - 1.1e-07 31.9 7.1 2.5e-07 30.7 7.1 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Glyco_transf_54 PF04666.13 KND91675.1 - 4.4e-10 38.9 0.0 2.8e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region YbhQ PF11076.8 KND91675.1 - 0.0046 17.0 0.5 0.0091 16.0 0.5 1.4 1 0 0 1 1 1 1 Putative inner membrane protein YbhQ DUF5134 PF17197.4 KND91675.1 - 2.8 7.8 6.6 3.1 7.7 3.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) zf-BED PF02892.15 KND91676.1 - 0.016 15.2 2.1 0.43 10.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger PRKCSH PF07915.13 KND91677.1 - 1.6e-15 57.9 0.0 4.6e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein GST_N_4 PF17172.4 KND91678.1 - 1.7e-16 60.8 0.0 3.2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KND91678.1 - 1.8e-14 53.3 0.1 3.8e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KND91678.1 - 1.6e-06 28.4 0.0 3.7e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 KND91678.1 - 0.0005 20.3 0.1 0.0016 18.7 0.0 1.8 1 1 1 2 2 2 1 SAM35, subunit of SAM coomplex OTU PF02338.19 KND91679.1 - 2.3e-20 73.4 2.0 7.1e-20 71.8 0.0 2.5 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KND91679.1 - 0.0016 18.0 0.5 0.11 12.0 0.0 2.9 3 1 0 3 3 3 2 Peptidase C65 Otubain INO80_Ies4 PF08193.11 KND91680.1 - 1.5e-80 270.7 21.5 1.8e-80 270.4 21.5 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 KND91681.1 - 4.7e-29 101.2 0.3 8.1e-29 100.4 0.0 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 KND91681.1 - 3.8e-24 85.1 0.1 6.2e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 KND91681.1 - 0.00013 21.7 0.1 0.00043 20.1 0.0 1.9 2 0 0 2 2 2 1 LisH SMC_ScpB PF04079.16 KND91681.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Segregation and condensation complex subunit ScpB DarA_C PF18789.1 KND91681.1 - 0.12 12.7 0.1 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 Defence against restriction A C-terminal IDO PF01231.18 KND91682.1 - 8.7e-35 120.3 0.0 1.2e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Pox_F11 PF04943.12 KND91682.1 - 0.17 10.9 0.0 0.53 9.3 0.1 1.6 2 0 0 2 2 2 0 Poxvirus F11 protein CDC14 PF08045.11 KND91683.1 - 6.5e-130 432.3 0.0 7.3e-130 432.2 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component IMUP PF15761.5 KND91683.1 - 0.27 11.9 3.3 0.62 10.8 1.0 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF347 PF03988.12 KND91684.1 - 0.053 13.7 1.2 0.11 12.7 1.2 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Pex24p PF06398.11 KND91685.1 - 2.6e-88 296.5 0.0 3e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KND91685.1 - 0.026 12.9 0.4 0.058 11.8 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) DUF639 PF04842.12 KND91685.1 - 0.13 11.6 0.8 0.6 9.5 0.2 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) polyprenyl_synt PF00348.17 KND91686.1 - 6.2e-62 209.0 0.0 7.7e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GRIP PF01465.20 KND91687.1 - 6.1e-16 58.1 0.0 1.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.9 KND91687.1 - 8.8e-05 22.6 144.3 0.18 11.8 16.4 8.7 4 3 4 8 8 8 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KND91687.1 - 0.00044 19.2 143.9 0.026 13.4 18.5 7.7 3 2 4 8 8 8 7 Spc7 kinetochore protein Phage_GP20 PF06810.11 KND91687.1 - 0.0006 19.6 6.3 0.0006 19.6 6.3 11.4 3 2 8 11 11 11 4 Phage minor structural protein GP20 GAS PF13851.6 KND91687.1 - 0.0043 16.4 141.6 0.058 12.7 20.5 9.1 3 3 6 9 9 9 3 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KND91687.1 - 0.015 15.5 2.7 0.015 15.5 2.7 12.1 6 2 6 12 12 11 0 Centrosomin N-terminal motif 1 PI_PP_I PF18363.1 KND91687.1 - 0.052 13.7 10.5 1.7 8.9 0.1 5.6 4 2 1 5 5 5 0 Phosphoinositide phosphatase insertion domain ERM PF00769.19 KND91687.1 - 0.7 9.7 168.9 0.2 11.5 20.6 7.4 4 1 3 7 7 7 0 Ezrin/radixin/moesin family ATG16 PF08614.11 KND91687.1 - 1.2 9.3 159.6 0.059 13.6 16.8 9.0 2 2 6 8 8 8 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KND91687.1 - 1.8 8.6 130.6 0.13 12.4 9.1 8.4 3 2 4 7 7 7 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KND91687.1 - 4.6 7.4 81.7 2.5 8.3 9.6 9.5 5 2 2 8 8 8 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 KND91687.1 - 6.7 4.8 109.0 0.13 10.5 1.5 7.3 4 2 1 5 5 5 0 Septation ring formation regulator, EzrA zinc_ribbon_10 PF10058.9 KND91688.1 - 1.9e-18 65.9 0.1 3.2e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Pro-rich PF15240.6 KND91688.1 - 0.0087 16.4 19.4 0.015 15.6 19.4 1.3 1 0 0 1 1 1 1 Proline-rich DUF3611 PF12263.8 KND91688.1 - 0.1 12.5 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) HalOD2 PF18547.1 KND91688.1 - 0.27 11.2 7.1 0.32 10.9 0.4 3.3 3 0 0 3 3 3 0 Halobacterial output domain 2 RNase_H PF00075.24 KND91689.1 - 1.2e-21 77.4 0.0 2.6e-21 76.3 0.0 1.6 1 1 0 1 1 1 1 RNase H NACHT PF05729.12 KND91690.1 - 3.6e-23 82.3 0.0 5.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND91690.1 - 0.0011 19.4 0.1 0.0037 17.6 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KND91690.1 - 0.0013 19.1 0.0 0.004 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain DAO PF01266.24 KND91692.1 - 2.5e-29 103.0 1.8 3.3e-29 102.6 1.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND91692.1 - 0.0025 16.9 0.5 0.0052 15.9 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND91692.1 - 0.0044 17.2 0.2 0.012 15.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KND91692.1 - 0.0093 15.3 0.1 0.024 13.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND91692.1 - 0.012 15.6 0.9 0.045 13.7 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KND91692.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND91692.1 - 0.073 12.3 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family TAL_FSA PF00923.19 KND91694.1 - 2.8e-46 158.2 0.0 3.7e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glyco_hydro_64 PF16483.5 KND91695.1 - 4.6e-43 147.9 0.0 6.3e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF4360 PF14273.6 KND91696.1 - 5.5e-46 156.7 0.2 6.2e-46 156.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Rep_fac-A_C PF08646.10 KND91697.1 - 8.1e-39 132.7 2.9 1.4e-37 128.6 1.2 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KND91697.1 - 4.3e-38 129.2 1.1 5e-37 125.8 0.2 2.7 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KND91697.1 - 5.2e-20 71.3 0.0 9.6e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KND91697.1 - 8.6e-13 48.1 1.4 4.8e-09 36.1 0.0 3.3 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain DUF4503 PF14951.6 KND91697.1 - 0.0014 17.2 0.3 0.0028 16.2 0.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4503) CDC24_OB3 PF17244.2 KND91697.1 - 0.0037 17.0 1.6 0.16 11.7 0.4 2.8 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 KND91697.1 - 0.0093 13.9 0.1 0.025 12.5 0.1 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5521) zf-like PF04071.12 KND91697.1 - 0.022 14.7 1.4 0.057 13.3 1.4 1.7 1 0 0 1 1 1 0 Cysteine-rich small domain ADH_zinc_N PF00107.26 KND91698.1 - 1.1e-24 86.8 0.1 1.8e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND91698.1 - 4.7e-20 73.0 0.0 8.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND91698.1 - 1.9e-09 37.4 0.0 1e-08 35.0 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PSII_BNR PF14870.6 KND91698.1 - 0.033 13.5 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Fungal_TACC PF12709.7 KND91699.1 - 3.4e-11 43.4 0.6 3.4e-11 43.4 0.6 5.6 4 2 2 6 6 6 2 Fungal Transforming acidic coiled-coil (TACC) proteins Spt20 PF12090.8 KND91699.1 - 3 7.4 37.1 2.5 7.6 9.3 2.7 2 0 0 2 2 2 0 Spt20 family Amidohydro_2 PF04909.14 KND91700.1 - 9.4e-26 91.3 0.8 1.4e-25 90.7 0.8 1.3 1 1 0 1 1 1 1 Amidohydrolase AMPK1_CBM PF16561.5 KND91701.1 - 0.0021 18.2 0.0 0.005 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SpoIIIAH PF12685.7 KND91701.1 - 0.049 13.5 2.4 0.068 13.0 2.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 KND91701.1 - 0.18 10.6 5.1 0.19 10.5 5.1 1.1 1 0 0 1 1 1 0 Presenilin Peroxin-3 PF04882.12 KND91701.1 - 0.22 10.5 8.1 0.3 10.0 8.1 1.3 1 0 0 1 1 1 0 Peroxin-3 Zip PF02535.22 KND91701.1 - 0.3 10.2 4.4 0.33 10.1 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 KND91701.1 - 0.77 8.5 8.9 1 8.1 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 KND91701.1 - 1.2 7.2 6.3 1.5 6.9 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 KND91701.1 - 2 7.5 21.8 2.7 7.1 21.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Sec3_C PF09763.9 KND91701.1 - 3 6.1 9.0 3.7 5.8 9.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Striatin PF08232.12 KND91701.1 - 5.6 7.5 7.7 9.4 6.8 7.7 1.3 1 0 0 1 1 1 0 Striatin family LSM PF01423.22 KND91702.1 - 3.1e-19 68.4 0.0 3.6e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain DLH PF01738.18 KND91703.1 - 1.1e-20 74.1 0.3 1.6e-19 70.4 0.3 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KND91703.1 - 0.0059 16.3 0.0 0.41 10.2 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KND91703.1 - 0.025 14.5 0.3 0.3 10.9 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold AMP-binding PF00501.28 KND91705.1 - 4.3e-71 239.7 0.0 5.1e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND91705.1 - 2.4e-18 66.9 0.1 6.3e-18 65.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KND91705.1 - 6.3e-17 61.2 0.1 1.6e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus KilA-N PF04383.13 KND91706.1 - 0.0003 20.6 0.0 0.0062 16.4 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain TPR_12 PF13424.6 KND91708.1 - 3e-51 171.6 15.0 1.8e-21 76.2 0.3 4.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 KND91708.1 - 1.4e-39 132.9 12.7 2.5e-12 46.3 0.1 5.5 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 KND91708.1 - 8.8e-16 56.7 4.2 0.001 18.9 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND91708.1 - 5.3e-12 45.0 1.4 0.013 15.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND91708.1 - 4.1e-08 32.7 2.0 0.22 11.7 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF676 PF05057.14 KND91708.1 - 5.2e-08 32.7 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KND91708.1 - 1.7e-07 32.1 0.1 1.7e-07 32.1 0.1 1.8 2 0 0 2 2 1 1 Alpha/beta hydrolase family TPR_MalT PF17874.1 KND91708.1 - 1.4e-06 28.0 3.2 3.5e-06 26.6 3.2 1.6 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 KND91708.1 - 1.8e-06 28.5 0.6 0.66 10.7 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND91708.1 - 3.5e-06 27.0 1.8 0.38 11.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND91708.1 - 3.7e-06 27.3 5.3 0.39 11.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND91708.1 - 1.4e-05 25.0 6.1 0.82 10.1 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 KND91708.1 - 0.00014 22.2 0.0 11 7.0 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat LCAT PF02450.15 KND91708.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase TPR_3 PF07720.12 KND91708.1 - 0.0064 16.5 1.8 31 4.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF726 PF05277.12 KND91708.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PGAP1 PF07819.13 KND91708.1 - 0.032 13.9 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein MIT PF04212.18 KND91708.1 - 0.033 14.3 2.3 6.4 6.9 0.0 4.1 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KND91708.1 - 0.062 14.2 4.5 53 5.0 0.1 4.6 4 1 0 4 4 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 KND91708.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1925 PF09094.11 KND91708.1 - 0.15 12.4 3.5 36 4.8 0.1 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF1925) Wzy_C_2 PF11846.8 KND91708.1 - 0.62 10.0 2.2 19 5.1 0.0 3.4 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 KND91708.1 - 2.7 8.8 4.7 1.3e+02 3.5 0.2 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Pkinase PF00069.25 KND91709.1 - 5.3e-41 140.7 0.0 8.2e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91709.1 - 5.8e-24 84.8 0.0 7.8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND91709.1 - 4.5e-06 26.2 0.0 6.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FHA PF00498.26 KND91709.1 - 5.8e-06 26.6 0.1 1.4e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND91709.1 - 0.0026 18.0 0.0 0.0057 17.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 KND91709.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND91709.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KND91712.1 - 0.00035 20.6 0.1 0.0011 19.0 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1e PF01406.19 KND91713.1 - 1.9e-109 365.7 0.0 3e-109 365.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KND91713.1 - 0.026 13.3 0.2 0.63 8.7 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (M) APH PF01636.23 KND91714.1 - 1.2e-21 77.7 0.1 1.5e-21 77.4 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND91714.1 - 0.0046 16.6 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND91714.1 - 0.018 14.7 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 KND91714.1 - 0.019 14.2 0.0 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 KND91714.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 2 0 0 2 2 2 0 Ecdysteroid kinase Glyco_hydro_125 PF06824.11 KND91715.1 - 5.2e-119 397.8 0.0 1.2e-95 320.8 0.0 2.1 1 1 1 2 2 2 2 Metal-independent alpha-mannosidase (GH125) WD40 PF00400.32 KND91718.1 - 2.2e-08 34.6 8.6 0.41 11.6 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND91718.1 - 0.048 14.0 0.4 11 6.4 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain HAD_2 PF13419.6 KND91719.1 - 1.1e-15 58.2 0.0 2e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND91719.1 - 7.8e-07 29.6 0.0 0.00023 21.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND91719.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like NT5C PF06941.12 KND91719.1 - 0.12 12.3 0.0 0.45 10.4 0.0 1.8 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Fungal_trans_2 PF11951.8 KND91721.1 - 8.1e-09 34.8 0.4 1.6e-08 33.8 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.6 KND91722.1 - 5.9e-07 29.7 4.9 0.00012 22.3 1.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND91722.1 - 0.00071 20.0 0.2 0.0018 18.7 0.2 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND91722.1 - 0.00072 19.5 5.2 0.35 11.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND91722.1 - 0.0017 18.1 2.6 0.038 13.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KND91722.1 - 0.011 15.4 0.2 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 KND91722.1 - 0.025 14.6 4.6 0.65 10.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND91722.1 - 0.16 12.2 1.1 0.74 10.1 1.1 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KND91722.1 - 0.42 11.6 4.7 3.8 8.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KND91722.1 - 1.1 10.0 8.9 2.1 9.1 3.4 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TerB_N PF13208.6 KND91723.1 - 7.7 6.2 7.9 10 5.8 7.9 1.2 1 0 0 1 1 1 0 TerB N-terminal domain Sugar_tr PF00083.24 KND91724.1 - 7.3e-52 176.7 20.2 4.1e-50 170.9 20.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91724.1 - 1.5e-17 63.6 33.3 4.6e-09 35.7 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 KND91724.1 - 0.0074 16.6 15.0 0.018 15.3 1.9 3.6 3 0 0 3 3 3 3 Putative inner membrane exporter, YdcZ Fungal_trans PF04082.18 KND91725.1 - 2.3e-10 40.0 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91725.1 - 8.3e-06 25.8 7.2 1.6e-05 24.9 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KND91726.1 - 6.9e-31 107.6 25.0 2.7e-30 105.7 25.0 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91726.1 - 3.4e-28 98.6 37.1 2.3e-21 76.1 20.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF647 PF04884.14 KND91727.1 - 3.6e-91 305.1 2.9 8.5e-91 303.9 2.9 1.6 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 KND91727.1 - 1.4e-61 207.6 0.0 2.3e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KND91727.1 - 1e-07 32.1 1.4 5.7e-07 29.7 1.4 2.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain APH PF01636.23 KND91728.1 - 1.1e-13 51.6 0.2 2.4e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KND91728.1 - 7.7e-05 22.8 7.4 0.00014 22.0 7.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Prok-RING_2 PF14445.6 KND91728.1 - 0.088 13.0 3.0 0.2 11.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 HMGL-like PF00682.19 KND91730.1 - 1.2e-76 257.7 0.2 1.8e-76 257.2 0.2 1.2 1 0 0 1 1 1 1 HMGL-like WSC PF01822.19 KND91732.1 - 1e-56 189.0 72.5 5.2e-17 61.8 11.7 5.5 5 1 0 5 5 5 4 WSC domain PQQ_3 PF13570.6 KND91732.1 - 2.1e-05 24.9 7.9 0.11 13.0 0.0 5.0 3 0 0 3 3 3 2 PQQ-like domain Prok-RING_1 PF14446.6 KND91732.1 - 0.022 14.7 0.5 0.091 12.7 0.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Toxin_35 PF10530.9 KND91732.1 - 0.077 13.0 12.4 0.77 9.8 0.7 3.6 3 0 0 3 3 3 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold DUF4908 PF16252.5 KND91732.1 - 3.6 7.1 9.4 7.7 6.0 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) NTP_transf_9 PF04248.12 KND91734.1 - 7.7e-36 121.9 0.1 5.1e-29 100.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Acetyltransf_8 PF13523.6 KND91735.1 - 1.8e-36 125.0 0.3 2.8e-36 124.4 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 KND91736.1 - 2.6e-21 76.5 0.1 2.6e-21 76.5 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial calcium uniporter Glyco_trans_4_4 PF13579.6 KND91736.1 - 0.025 15.0 0.2 0.057 13.9 0.2 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KND91736.1 - 0.041 13.9 0.2 0.072 13.1 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ArfGap PF01412.18 KND91737.1 - 4.8e-38 129.8 0.6 9e-38 129.0 0.6 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Haem_bd PF14376.6 KND91737.1 - 0.029 14.3 0.6 0.065 13.2 0.6 1.6 1 0 0 1 1 1 0 Haem-binding domain Oxysterol_BP PF01237.18 KND91738.1 - 1.6e-109 366.1 0.0 4.3e-109 364.8 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KND91738.1 - 1.3e-37 128.0 0.5 3.7e-37 126.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KND91738.1 - 2e-07 31.5 0.1 1.1e-06 29.1 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_17 PF18012.1 KND91738.1 - 0.043 13.5 0.3 0.51 10.1 0.3 2.3 2 0 0 2 2 2 0 PH domain Tfb5 PF06331.12 KND91739.1 - 1.4e-23 82.7 1.6 1.9e-23 82.2 1.6 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Mito_carr PF00153.27 KND91740.1 - 8.1e-48 160.3 0.1 1.3e-16 60.2 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.17 KND91741.1 - 1.1e-44 151.3 1.6 1.7e-44 150.7 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family His_biosynth PF00977.21 KND91744.1 - 9.3e-47 159.4 0.1 3.6e-46 157.5 0.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KND91744.1 - 3.5e-19 69.3 0.0 5.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KND91744.1 - 1.5e-07 31.4 0.0 1.9e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KND91744.1 - 9.6e-07 28.6 0.1 3.7e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 KND91744.1 - 0.0072 15.5 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Pantoate_transf PF02548.15 KND91744.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Peptidase_C26 PF07722.13 KND91744.1 - 0.11 12.3 0.1 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 ODC_AZ PF02100.17 KND91745.1 - 1.7e-44 150.5 0.3 2.3e-44 150.0 0.3 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ank_2 PF12796.7 KND91746.1 - 1e-47 160.6 2.9 8.8e-12 45.5 0.0 5.8 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND91746.1 - 1.9e-40 136.7 7.7 4.5e-09 36.7 0.0 9.4 7 3 2 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 KND91746.1 - 1e-36 123.8 13.2 1.4e-05 25.3 0.0 12.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_3 PF13606.6 KND91746.1 - 9.2e-33 108.6 6.7 0.0014 18.9 0.0 12.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KND91746.1 - 2.2e-32 110.7 10.5 7.3e-10 38.9 0.0 8.0 6 2 3 9 9 9 6 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 KND91746.1 - 2.6e-05 23.6 0.1 4.8e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 KND91746.1 - 0.052 13.5 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain MFS_1 PF07690.16 KND91749.1 - 5.5e-36 124.2 46.2 5.5e-36 124.2 46.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91749.1 - 2.1e-09 36.8 14.6 2.1e-09 36.8 14.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter APH PF01636.23 KND91751.1 - 4.7e-12 46.3 0.0 1.1e-11 45.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 KND91752.1 - 2.9e-15 56.0 0.1 4.9e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ldh_2 PF02615.14 KND91753.1 - 2.6e-71 240.5 0.2 5.9e-71 239.3 0.2 1.5 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase Retrotran_gag_3 PF14244.6 KND91753.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Amidohydro_2 PF04909.14 KND91754.1 - 6.2e-26 91.9 0.5 7.7e-26 91.5 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 KND91755.1 - 1.9e-08 33.7 27.3 2.6e-05 23.3 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5464 PF17552.2 KND91755.1 - 1.4 9.3 10.5 0.65 10.3 3.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5464) SRR1 PF07985.12 KND91756.1 - 2.6e-14 53.0 0.0 4.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 SRR1 APH PF01636.23 KND91757.1 - 2.9e-11 43.8 0.0 1.2e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_17 PF00332.18 KND91759.1 - 2.3e-05 24.2 2.1 0.097 12.2 0.1 2.2 1 1 0 2 2 2 2 Glycosyl hydrolases family 17 SARAF PF06682.12 KND91759.1 - 0.37 10.4 0.0 0.37 10.4 0.0 2.6 1 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5111 PF17138.4 KND91759.1 - 0.97 9.3 4.7 2.2 8.1 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) Pkinase PF00069.25 KND91760.1 - 0.15 11.4 0.0 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Zn_clus PF00172.18 KND91761.1 - 5.3e-07 29.7 2.1 9.4e-07 28.9 2.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND91761.1 - 0.001 18.0 0.9 0.08 11.7 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain WD40 PF00400.32 KND91762.1 - 4.2e-12 46.4 6.3 0.46 11.4 0.0 7.4 7 1 1 8 8 8 5 WD domain, G-beta repeat Nop14 PF04147.12 KND91762.1 - 0.58 8.3 15.9 0.89 7.7 15.9 1.3 1 0 0 1 1 1 0 Nop14-like family AAA_12 PF13087.6 KND91763.1 - 8.8e-32 110.3 0.0 2.5e-31 108.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KND91763.1 - 1.1e-20 74.5 0.0 1.4e-19 71.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND91763.1 - 8.7e-09 35.9 0.0 8.5e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND91763.1 - 2.9e-07 30.4 0.1 0.00051 19.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KND91763.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 KND91763.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KND91763.1 - 0.12 12.7 0.0 0.7 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Plasmodium_Vir PF05795.11 KND91763.1 - 2.7 7.3 4.4 2.1 7.7 2.5 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ank_2 PF12796.7 KND91764.1 - 6.1e-05 23.5 0.0 0.0011 19.5 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KND91764.1 - 8.4e-05 22.8 0.1 0.00062 20.1 0.0 2.7 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KND91764.1 - 0.00063 20.0 0.2 0.026 15.0 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KND91764.1 - 0.0023 18.2 0.1 0.0083 16.4 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND91764.1 - 0.0086 16.6 0.1 0.11 13.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) NACHT PF05729.12 KND91764.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Methyltransf_23 PF13489.6 KND91765.1 - 2.9e-11 43.5 0.0 3.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91765.1 - 6.3e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND91765.1 - 1.7e-05 25.4 0.0 5.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91765.1 - 0.00036 21.2 0.0 0.0016 19.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND91765.1 - 0.0055 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PQQ_3 PF13570.6 KND91766.1 - 0.0022 18.4 1.9 4.7 7.8 0.0 3.1 2 1 1 3 3 3 2 PQQ-like domain GCD14 PF08704.10 KND91767.1 - 0.02 14.5 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DNA_primase_lrg PF04104.14 KND91768.1 - 9.2e-84 281.0 0.0 2.3e-83 279.7 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit Mut7-C PF01927.16 KND91769.1 - 0.0057 16.8 0.2 0.0061 16.7 0.2 1.1 1 0 0 1 1 1 1 Mut7-C RNAse domain zf-FPG_IleRS PF06827.14 KND91769.1 - 0.0062 16.4 1.3 0.11 12.4 0.1 2.2 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 KND91769.1 - 0.29 11.1 3.7 0.57 10.1 3.1 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF1660 PF07874.11 KND91769.1 - 0.35 11.4 3.7 5.6 7.5 0.1 2.3 1 1 1 2 2 2 0 Prophage protein (DUF1660) Carla_C4 PF01623.17 KND91769.1 - 1.4 8.9 6.2 2.4 8.2 1.2 2.2 1 1 1 2 2 2 0 Carlavirus putative nucleic acid binding protein zinc_ribbon_9 PF14369.6 KND91769.1 - 5.1 7.4 7.8 7.8 6.9 0.4 2.8 3 0 0 3 3 3 0 zinc-ribbon IMUP PF15761.5 KND91769.1 - 5.3 7.8 9.9 8.5 7.1 9.9 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Clr5 PF14420.6 KND91770.1 - 7.8e-23 80.5 0.5 1.5e-22 79.5 0.5 1.5 1 0 0 1 1 1 1 Clr5 domain DUF5340 PF17275.2 KND91770.1 - 0.028 14.5 0.1 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5340) Pkinase PF00069.25 KND91771.1 - 1.8e-44 152.1 0.0 8e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND91771.1 - 3.5e-28 98.6 0.0 5.9e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KND91771.1 - 0.0065 15.3 0.0 0.012 14.4 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase Cupin_2 PF07883.11 KND91772.1 - 1.2e-14 53.7 1.0 1.7e-14 53.3 1.0 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KND91772.1 - 0.046 13.6 0.5 0.063 13.2 0.5 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KND91772.1 - 0.055 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Lipase_3 PF01764.25 KND91773.1 - 1.9e-31 108.9 0.0 2.6e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KND91773.1 - 2.2e-05 25.1 1.7 3.1e-05 24.7 1.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND91773.1 - 6.4e-05 22.3 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KND91773.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KND91773.1 - 0.1 12.7 0.7 0.17 12.0 0.7 1.3 1 0 0 1 1 1 0 Thioesterase domain LRR_6 PF13516.6 KND91774.1 - 1.5e-06 27.8 0.0 0.086 12.9 0.1 5.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KND91774.1 - 0.032 14.0 1.1 0.17 11.7 0.5 2.6 3 0 0 3 3 3 0 Leucine rich repeat NinF PF05810.12 KND91774.1 - 1.9 8.4 3.9 9.7 6.2 0.1 3.0 3 0 0 3 3 3 0 NinF protein SNF2_N PF00176.23 KND91775.1 - 1.5e-48 165.3 0.5 2.8e-43 148.0 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KND91775.1 - 1.8e-15 57.3 0.0 6e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KND91775.1 - 1.4e-06 28.0 11.2 1.4e-06 28.0 11.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND91775.1 - 0.0011 19.3 12.9 0.0011 19.3 12.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND91775.1 - 0.0018 18.1 10.9 0.0018 18.1 10.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND91775.1 - 0.0029 17.4 10.8 0.0029 17.4 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 KND91775.1 - 0.0066 15.4 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_UBOX PF13445.6 KND91775.1 - 2.6 8.2 11.6 6.5 6.9 11.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 KND91775.1 - 2.9 8.0 10.8 1.4 9.0 2.2 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-rbx1 PF12678.7 KND91775.1 - 9.5 6.6 12.9 1.1 9.6 8.0 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain EF1_GNE PF00736.19 KND91776.1 - 8.3e-30 102.8 1.9 1.5e-29 102.0 1.9 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KND91776.1 - 5.1e-13 49.2 7.9 1.3e-12 47.9 7.9 1.8 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KND91776.1 - 0.0047 17.1 0.4 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain UBA2_C PF16195.5 KND91776.1 - 0.092 13.4 3.9 0.16 12.7 3.9 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus GST_C PF00043.25 KND91776.1 - 0.099 12.9 0.1 0.4 10.9 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Orn_Arg_deC_N PF02784.16 KND91777.1 - 3.5e-84 282.1 0.0 4.9e-84 281.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KND91777.1 - 1.4e-18 66.9 0.0 2.6e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.11 KND91778.1 - 5.2e-83 278.0 0.0 1.1e-82 276.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KND91778.1 - 1.9e-26 93.2 0.0 1.1e-17 64.6 0.0 3.5 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND91778.1 - 3.6e-08 33.5 0.0 1.3e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 KND91778.1 - 0.018 15.1 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 UvrA interaction domain THDPS_N_2 PF14805.6 KND91778.1 - 0.06 13.6 0.7 0.15 12.3 0.7 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Taxilin PF09728.9 KND91779.1 - 1e-84 284.3 64.9 2.6e-83 279.7 64.9 2.2 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 KND91779.1 - 0.0035 17.8 0.2 0.0035 17.8 0.2 4.0 2 2 2 5 5 5 1 Domain of unknown function (DUF4810) Sec20 PF03908.13 KND91779.1 - 3.6 7.6 13.2 0.46 10.4 1.0 3.9 3 1 1 4 4 4 0 Sec20 Peptidase_M48_N PF16491.5 KND91780.1 - 8.1e-63 211.6 8.8 8.1e-63 211.6 8.8 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KND91780.1 - 6.9e-44 150.0 0.1 1.1e-43 149.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KND91780.1 - 3.9e-06 26.3 0.0 7.2e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M16_C PF05193.21 KND91781.1 - 9.2e-18 64.9 0.0 1.1e-13 51.6 0.0 3.8 4 1 1 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KND91781.1 - 4.6e-09 36.4 0.0 8.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Methyltransf_24 PF13578.6 KND91782.1 - 6.6e-09 36.7 0.1 1.2e-08 35.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 KND91782.1 - 1.9e-07 30.5 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase ADH_zinc_N PF00107.26 KND91782.1 - 0.049 13.6 0.5 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Peptidase_S8 PF00082.22 KND91783.1 - 3.1e-29 102.2 14.0 7.3e-29 101.0 14.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND91783.1 - 5.9e-13 49.3 0.1 2.8e-12 47.1 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 Methyltransf_2 PF00891.18 KND91784.1 - 4.8e-23 81.6 0.0 7.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 KND91784.1 - 0.19 11.0 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ig_GlcNase PF18368.1 KND91786.1 - 4.1e-33 113.7 0.0 1.2e-32 112.2 0.0 1.8 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Mannosidase_ig PF17786.1 KND91786.1 - 4e-05 24.1 0.3 0.00018 22.1 0.1 2.1 1 1 1 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KND91786.1 - 0.00013 21.6 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KND91787.1 - 7.2e-11 42.7 0.1 1.5e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_31 PF01055.26 KND91788.1 - 2.6e-95 320.2 0.1 3.6e-95 319.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KND91788.1 - 6e-13 48.9 0.1 3.3e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KND91788.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) MFS_1 PF07690.16 KND91789.1 - 1.2e-28 100.1 31.5 1.2e-28 100.1 31.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND91789.1 - 1.8e-07 30.4 17.1 2.9e-06 26.4 17.5 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter 7tm_3 PF00003.22 KND91789.1 - 0.046 13.4 7.2 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR CcmH PF03918.14 KND91789.1 - 0.13 11.5 0.1 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF4381 PF14316.6 KND91789.1 - 0.16 12.2 0.4 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NACHT PF05729.12 KND91791.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain zf_ZIC PF18366.1 KND91791.1 - 0.031 14.4 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 Zic proteins zinc finger domain KAP_NTPase PF07693.14 KND91791.1 - 0.045 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain zf-Di19 PF05605.12 KND91791.1 - 1.2 9.5 14.5 0.073 13.4 0.8 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KND91791.1 - 1.8 9.7 0.0 1.8 9.7 0.0 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger Metallophos PF00149.28 KND91792.1 - 2.1e-16 61.0 0.0 4.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SAP PF02037.27 KND91793.1 - 1.6e-13 50.0 0.2 2.9e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 KND91793.1 - 1.9e-05 24.3 3.4 1.9e-05 24.3 3.4 2.1 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain HeH PF12949.7 KND91793.1 - 0.042 13.6 0.6 0.12 12.1 0.6 1.8 1 1 0 1 1 1 0 HeH/LEM domain EBP50_C PF09007.11 KND91793.1 - 0.077 14.0 3.8 0.16 12.9 3.8 1.6 1 0 0 1 1 1 0 EBP50, C-terminal MBOAT PF03062.19 KND91795.1 - 3.3e-39 135.2 11.8 3.3e-39 135.2 11.8 2.3 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Ferritin_2 PF13668.6 KND91796.1 - 1.8e-06 28.2 2.8 3.2e-06 27.4 2.8 1.4 1 0 0 1 1 1 1 Ferritin-like domain DnaJ PF00226.31 KND91797.1 - 2.1e-20 72.6 1.9 2.1e-20 72.6 1.9 2.0 2 0 0 2 2 2 1 DnaJ domain Metallophos PF00149.28 KND91798.1 - 5.8e-12 46.5 0.0 1.3e-11 45.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND91798.1 - 1.3e-05 25.5 0.1 0.00021 21.5 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 KND91798.1 - 0.14 11.4 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily PSDC PF12588.8 KND91799.1 - 8.1e-56 187.9 0.0 1.3e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase MFS_1 PF07690.16 KND91799.1 - 3.1e-41 141.5 51.9 2.6e-40 138.5 51.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PS_Dcarbxylase PF02666.15 KND91799.1 - 1.9e-17 63.5 0.0 3.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Hemerythrin PF01814.23 KND91799.1 - 0.19 12.4 1.5 7.4 7.2 0.2 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Abhydrolase_1 PF00561.20 KND91801.1 - 8.9e-31 107.5 0.1 8e-30 104.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND91801.1 - 1.8e-17 64.7 0.2 2.3e-17 64.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND91801.1 - 2.9e-09 36.6 0.0 9.3e-09 34.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KND91801.1 - 0.00074 18.6 0.0 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase PF07224.11 KND91801.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KND91801.1 - 0.0015 17.5 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 KND91801.1 - 0.0029 17.2 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family EHN PF06441.12 KND91801.1 - 0.0073 16.7 0.1 0.11 12.9 0.0 2.5 2 1 0 2 2 2 1 Epoxide hydrolase N terminus Abhydro_lipase PF04083.16 KND91801.1 - 0.17 11.5 0.0 0.44 10.2 0.0 1.6 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region NUDIX PF00293.28 KND91803.1 - 2.5e-12 47.0 0.1 3.6e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain p450 PF00067.22 KND91804.1 - 2.4e-51 174.9 0.0 3.6e-37 128.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 BTB PF00651.31 KND91805.1 - 0.027 14.7 0.0 0.068 13.4 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Peptidase_C97 PF05903.14 KND91807.1 - 0.0012 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 KND91807.1 - 0.0058 16.3 0.1 0.0085 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF778 PF05608.12 KND91807.1 - 0.015 15.7 0.2 0.044 14.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF778) LRAT PF04970.13 KND91807.1 - 0.086 13.1 0.4 0.76 10.1 0.4 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase MFS_1 PF07690.16 KND91808.1 - 0.012 14.6 0.0 0.013 14.5 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily LPG_synthase_TM PF03706.13 KND91809.1 - 0.013 15.1 0.1 0.014 14.9 0.1 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DEAD PF00270.29 KND91810.1 - 2.1e-45 154.6 0.0 3.4e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND91810.1 - 1.2e-24 86.8 0.1 2.1e-23 82.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KND91810.1 - 1.2e-19 70.3 0.6 2.2e-19 69.4 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 KND91810.1 - 2.8e-05 23.4 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KND91810.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Nop14 PF04147.12 KND91810.1 - 0.083 11.1 5.0 0.11 10.7 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 KND91810.1 - 8.3 6.4 14.2 14 5.6 14.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MALT1_Ig PF18703.1 KND91811.1 - 0.096 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 MALT1 Ig-like domain NMO PF03060.15 KND91813.1 - 1.3e-50 172.7 1.0 1.9e-50 172.2 1.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND91813.1 - 2.4e-08 33.4 1.4 3.5e-07 29.6 0.2 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KND91813.1 - 3.3e-06 26.4 3.2 3.3e-06 26.4 3.2 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF1729 PF08354.10 KND91813.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Sdh_cyt PF01127.22 KND91814.1 - 4e-16 59.1 2.5 5.7e-16 58.6 2.5 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Fungal_trans PF04082.18 KND91815.1 - 3.7e-19 68.8 0.3 7.8e-19 67.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91815.1 - 4.8e-09 36.2 8.1 8.3e-09 35.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 KND91816.1 - 1.1e-67 229.1 0.0 1.4e-67 228.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ADH_zinc_N PF00107.26 KND91816.1 - 0.0005 20.0 0.0 0.0027 17.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.13 KND91816.1 - 0.0037 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DJ-1_PfpI PF01965.24 KND91817.1 - 6.5e-15 55.3 0.0 1.9e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KND91817.1 - 3.9e-06 26.7 0.0 6e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 KND91817.1 - 0.0008 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 KND91817.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 KND91817.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 Opi1 PF08618.10 KND91818.1 - 1.3e-38 133.4 10.3 3.6e-28 99.0 2.7 3.3 2 1 1 3 3 3 3 Transcription factor Opi1 Beta_propel PF09826.9 KND91819.1 - 0.017 14.0 0.0 0.1 11.4 0.0 2.2 1 1 0 1 1 1 0 Beta propeller domain TAF6_C PF07571.13 KND91821.1 - 1.9e-27 95.4 0.0 4e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KND91821.1 - 1.6e-21 76.2 0.5 2.8e-21 75.5 0.5 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 KND91821.1 - 0.005 17.2 0.5 0.01 16.2 0.5 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KND91821.1 - 0.047 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 KND91821.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MR_MLE_C PF13378.6 KND91824.1 - 9.5e-15 54.7 0.1 3.1e-12 46.5 0.0 2.2 1 1 1 2 2 2 2 Enolase C-terminal domain-like Sulfatase PF00884.23 KND91825.1 - 8.9e-22 77.9 0.2 2e-21 76.7 0.1 1.7 1 1 1 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KND91825.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KND91825.1 - 0.008 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Ribosomal_L34 PF00468.17 KND91826.1 - 8e-10 38.5 10.7 1.3e-09 37.8 10.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3 PF00933.21 KND91827.1 - 2.4e-47 161.9 0.0 3.8e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KND91827.1 - 1.1e-44 152.9 0.1 3.1e-44 151.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KND91827.1 - 1.6e-20 73.0 0.6 2.9e-20 72.1 0.6 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.6 KND91827.1 - 0.02 15.0 0.3 0.05 13.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) DUF11 PF01345.18 KND91827.1 - 0.073 13.4 0.1 0.26 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 CARDB PF07705.11 KND91827.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 CARDB MFS_1 PF07690.16 KND91828.1 - 9.7e-32 110.3 29.0 1.6e-31 109.6 28.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 KND91828.1 - 0.81 9.5 3.3 2 8.3 0.9 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain NTF2 PF02136.20 KND91829.1 - 0.0084 16.7 1.4 0.085 13.4 1.4 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KND91829.1 - 0.017 15.1 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 YscW PF09619.10 KND91829.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) tRNA-synt_1g PF09334.11 KND91830.1 - 3.8e-48 164.2 1.2 1e-47 162.7 0.5 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (M) GrpB PF04229.14 KND91830.1 - 2.2e-47 161.2 0.0 4.1e-47 160.3 0.0 1.5 1 0 0 1 1 1 1 GrpB protein Acetyltransf_3 PF13302.7 KND91830.1 - 7.1e-24 85.0 0.0 4.9e-23 82.3 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 KND91830.1 - 7.5e-09 34.4 0.2 1.1e-08 33.9 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KND91830.1 - 9.8e-05 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FR47 PF08445.10 KND91830.1 - 0.00073 19.5 0.2 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 KND91830.1 - 0.0019 17.9 1.6 0.059 13.1 0.7 3.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1631 PF07793.11 KND91830.1 - 0.13 10.7 0.4 0.19 10.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Acetyltransf_1 PF00583.25 KND91830.1 - 0.14 12.4 0.2 1.6 9.0 0.1 2.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family AAA_18 PF13238.6 KND91831.1 - 2.1e-08 34.8 0.0 3.7e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KND91831.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KND91831.1 - 0.15 12.2 0.0 0.66 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 KND91832.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ParA PF10609.9 KND91835.1 - 2.1e-90 302.5 0.0 2.6e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KND91835.1 - 2.1e-10 40.8 0.0 9.7e-09 35.4 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KND91835.1 - 4.2e-06 26.2 0.1 0.0001 21.7 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KND91835.1 - 1.2e-05 25.3 0.2 0.0014 18.6 0.2 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KND91835.1 - 5.5e-05 22.5 0.4 0.00044 19.5 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KND91835.1 - 0.00076 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND91835.1 - 0.0029 16.6 0.5 0.0046 16.0 0.5 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 KND91835.1 - 0.0086 15.6 0.1 0.022 14.3 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 KND91835.1 - 0.015 15.2 0.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KND91835.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 KND91835.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin CLP1_P PF16575.5 KND91835.1 - 0.21 11.3 0.1 0.42 10.4 0.1 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KND91835.1 - 0.22 11.9 1.0 0.49 10.8 1.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KND91835.1 - 0.31 10.9 2.4 0.32 10.9 1.2 1.6 2 0 0 2 2 2 0 RsgA GTPase DUF202 PF02656.15 KND91836.1 - 0.24 11.9 4.6 3.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) NOB1_Zn_bind PF08772.11 KND91837.1 - 1.9e-32 111.2 2.2 3.2e-32 110.5 2.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KND91837.1 - 1.3e-28 99.3 0.1 3.3e-28 98.0 0.0 1.7 2 0 0 2 2 2 1 PIN domain of ribonuclease WRNPLPNID PF15017.6 KND91837.1 - 0.054 14.4 4.0 0.054 14.4 4.0 2.5 2 1 1 3 3 3 0 Putative WW-binding domain and destruction box PIN_5 PF08745.11 KND91837.1 - 0.12 11.8 0.1 7.9 5.8 0.0 2.6 2 1 1 3 3 3 0 PINc domain ribonuclease Rhodanese_C PF12368.8 KND91837.1 - 0.13 12.6 0.4 0.22 11.9 0.4 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal zf-NADH-PPase PF09297.11 KND91837.1 - 0.17 11.5 5.2 0.1 12.3 1.0 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RRP7 PF12923.7 KND91837.1 - 2.1 8.5 5.2 0.21 11.7 0.3 1.7 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SAM_decarbox PF01536.16 KND91838.1 - 5.5e-131 436.8 0.0 6.7e-131 436.5 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Aa_trans PF01490.18 KND91839.1 - 1.5e-56 191.9 33.0 1.7e-56 191.7 33.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Corona_7 PF02398.16 KND91840.1 - 1.5 9.4 6.1 0.29 11.7 0.3 2.4 2 1 0 2 2 2 0 Coronavirus protein 7 Zn_clus PF00172.18 KND91841.1 - 2.6e-17 62.7 27.2 1.1e-08 35.0 9.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91841.1 - 1.6e-06 27.3 0.1 2.7e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Vir_act_alpha_C PF10400.9 KND91841.1 - 0.028 15.1 0.0 0.076 13.7 0.0 1.8 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF639 PF04842.12 KND91841.1 - 0.15 11.4 0.1 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) cobW PF02492.19 KND91842.1 - 1.4e-43 148.5 2.1 2.1e-43 148.0 2.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KND91842.1 - 9.8e-18 63.9 0.1 5.3e-14 51.9 0.0 2.8 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 KND91842.1 - 0.00022 21.7 0.6 0.00072 20.0 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND91842.1 - 0.002 18.1 1.4 0.95 9.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 KND91842.1 - 0.0067 16.4 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KND91842.1 - 0.0078 15.8 0.5 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 KND91842.1 - 0.0078 16.0 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MobB PF03205.14 KND91842.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 KND91842.1 - 0.044 12.8 0.4 2.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KND91842.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KND91842.1 - 0.08 13.3 1.1 0.39 11.0 1.1 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KND91842.1 - 0.13 12.2 0.1 0.45 10.4 0.1 2.0 1 0 0 1 1 1 0 NACHT domain PI3K_1B_p101 PF10486.9 KND91842.1 - 4.8 4.8 5.1 0.52 8.0 0.2 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hexapep PF00132.24 KND91843.1 - 4.5e-15 54.7 10.2 1.1e-10 40.8 1.5 3.9 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KND91843.1 - 1.5e-10 40.7 12.7 3.7e-08 33.0 0.9 4.0 5 0 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KND91843.1 - 0.0099 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase SOR PF07682.11 KND91843.1 - 0.035 13.0 0.0 0.72 8.7 0.0 2.0 2 0 0 2 2 2 0 Sulphur oxygenase reductase Fungal_trans_2 PF11951.8 KND91844.1 - 1.8e-18 66.5 0.4 2.9e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KND91844.1 - 0.017 15.8 0.0 0.077 13.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KND91844.1 - 0.027 15.2 0.0 0.073 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain QCR10 PF09796.9 KND91846.1 - 3.7e-23 81.3 0.2 4.9e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DIE2_ALG10 PF04922.12 KND91847.1 - 1.6e-124 416.2 4.7 9.5e-124 413.7 4.7 1.9 1 1 0 1 1 1 1 DIE2/ALG10 family Sas10_Utp3 PF04000.15 KND91849.1 - 6.8e-17 61.9 0.8 6.8e-17 61.9 0.8 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4201 PF13870.6 KND91851.1 - 0.001 18.9 20.5 0.0014 18.4 18.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 KND91851.1 - 0.02 13.8 15.0 0.035 13.0 15.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DHQ_synthase PF01761.20 KND91851.1 - 0.051 12.7 0.1 0.078 12.1 0.1 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase Tli4_N PF18443.1 KND91851.1 - 0.091 13.1 6.3 2.4 8.5 1.9 2.6 2 1 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain PHM7_cyt PF14703.6 KND91851.1 - 1 9.6 8.8 0.93 9.7 6.7 1.9 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter IPP-2 PF04979.14 KND91852.1 - 1.5e-23 84.0 8.0 1.5e-23 84.0 8.0 1.9 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Zn_clus PF00172.18 KND91853.1 - 3.5e-14 52.6 24.5 3.9e-07 30.1 7.7 2.7 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91853.1 - 1.3e-10 40.8 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 KND91855.1 - 8.7e-05 22.6 0.1 0.0001 22.3 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KND91855.1 - 0.0016 17.8 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KND91855.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 KND91855.1 - 0.23 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 KND91856.1 - 9.3e-14 51.9 0.0 2.7e-13 50.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KND91856.1 - 0.0015 17.5 0.0 0.31 9.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KND91856.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FAD_binding_4 PF01565.23 KND91860.1 - 1.8e-20 73.1 1.3 3.6e-20 72.1 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND91860.1 - 2.3e-05 24.4 0.1 5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FACT-Spt16_Nlob PF14826.6 KND91861.1 - 2.8e-17 63.0 0.1 7e-16 58.4 0.1 2.8 1 1 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain DPPIV_N PF00930.21 KND91862.1 - 5.4e-99 331.3 0.1 7.7e-99 330.8 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KND91862.1 - 5.5e-39 133.9 1.2 9.8e-39 133.0 1.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KND91862.1 - 0.0059 17.2 1.6 0.064 13.8 0.1 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.18 KND91863.1 - 5.9e-09 35.9 6.1 9.5e-09 35.2 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.14 KND91864.1 - 7.1e-69 232.7 7.5 1e-68 232.1 7.5 1.1 1 0 0 1 1 1 1 Phosphoesterase family tRNA_SAD PF07973.14 KND91865.1 - 8.9e-07 28.9 1.1 1.5e-06 28.2 1.1 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 KND91865.1 - 2.3e-06 26.4 0.3 2.9e-06 26.1 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Peptidase_S10 PF00450.22 KND91866.1 - 2.8e-73 247.7 0.1 3.8e-73 247.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Phospholip_A2_3 PF09056.11 KND91867.1 - 4.6e-43 146.4 0.6 7.6e-43 145.7 0.6 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 KND91867.1 - 0.047 13.6 0.5 0.085 12.8 0.0 1.6 2 0 0 2 2 2 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Phage_T7_Capsid PF05396.11 KND91867.1 - 0.11 12.9 0.7 0.2 12.0 0.7 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein CN_hydrolase PF00795.22 KND91868.1 - 5e-38 130.9 0.0 7.4e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF899 PF05988.12 KND91869.1 - 2.5e-76 256.0 0.0 2.9e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 KND91869.1 - 0.021 14.7 0.0 0.056 13.4 0.0 1.7 1 1 1 2 2 2 0 AhpC/TSA family zf-C2H2 PF00096.26 KND91870.1 - 5.6e-10 39.1 16.0 0.037 14.5 1.3 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND91870.1 - 7.7e-10 38.8 16.0 0.04 14.7 0.1 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND91870.1 - 1.7e-07 31.3 6.9 0.0098 16.2 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND91870.1 - 2.3e-06 27.8 9.0 0.011 16.0 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KND91870.1 - 0.00047 20.4 10.2 0.012 15.9 1.1 3.0 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KND91870.1 - 0.00061 19.7 0.6 0.81 9.8 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND91870.1 - 0.001 19.4 0.3 0.001 19.4 0.3 5.3 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_2 PF12756.7 KND91870.1 - 0.0027 18.0 9.0 0.018 15.3 0.5 4.0 2 2 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 KND91870.1 - 0.0055 17.0 7.1 1 9.7 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KND91870.1 - 0.0078 16.3 9.4 0.054 13.6 0.7 3.1 2 1 1 3 3 3 2 Zinc ribbon domain IBR PF01485.21 KND91870.1 - 0.04 14.1 0.3 0.04 14.1 0.3 3.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_L34e PF01199.18 KND91870.1 - 0.054 13.8 4.0 1.3 9.4 0.1 3.4 3 1 2 5 5 5 0 Ribosomal protein L34e Actin_micro PF17003.5 KND91870.1 - 0.067 12.4 0.9 3.4 6.7 0.3 2.1 2 0 0 2 2 2 0 Putative actin-like family zinc_ribbon_9 PF14369.6 KND91870.1 - 0.075 13.3 5.6 5.5 7.3 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon zinc_ribbon_5 PF13719.6 KND91870.1 - 0.094 12.5 2.7 3.7 7.4 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 KND91870.1 - 0.097 12.5 7.7 0.33 10.8 0.2 3.5 2 2 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 KND91870.1 - 0.2 12.1 4.8 18 5.8 0.7 4.0 2 2 1 3 3 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Mss51 PF13824.6 KND91870.1 - 0.22 11.6 7.9 7.9 6.7 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_UBZ PF18439.1 KND91870.1 - 0.35 10.5 0.0 0.35 10.5 0.0 3.9 5 0 0 5 5 4 0 Ubiquitin-Binding Zinc Finger Elf1 PF05129.13 KND91870.1 - 0.62 10.2 6.7 16 5.6 0.6 3.7 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like zf-trcl PF13451.6 KND91870.1 - 0.68 9.9 6.0 0.49 10.3 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-RING_5 PF14634.6 KND91870.1 - 1.1 9.3 13.4 2 8.5 5.4 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zinc_ribbon_15 PF17032.5 KND91870.1 - 1.2 9.9 4.8 3.6 8.4 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon family zf-C2H2_12 PF18658.1 KND91870.1 - 1.5 8.5 3.6 2 8.1 2.1 2.0 2 1 0 2 2 1 0 Zinc-finger C2H2-type FOXP-CC PF16159.5 KND91870.1 - 1.7 9.4 4.6 1 10.0 0.5 2.7 2 1 0 2 2 1 0 FOXP coiled-coil domain DZR PF12773.7 KND91870.1 - 2.5 8.2 8.4 16 5.6 1.7 3.3 3 0 0 3 3 3 0 Double zinc ribbon Peptidase_S8 PF00082.22 KND91871.1 - 2.3e-18 66.5 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family B56 PF01603.20 KND91872.1 - 1.4e-188 627.1 1.0 1.7e-188 626.8 1.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KND91872.1 - 4.2e-05 23.5 0.5 0.34 10.8 0.1 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal TRAPP PF04051.16 KND91874.1 - 9.3e-42 142.2 0.0 1.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCS1_N PF08740.11 KND91875.1 - 5.5e-47 160.2 0.9 5.5e-47 160.2 0.9 2.1 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KND91875.1 - 9.7e-18 64.9 0.0 4.4e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND91875.1 - 0.00039 20.2 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain CDC45 PF02724.14 KND91875.1 - 0.008 14.5 14.4 0.012 14.0 14.4 1.1 1 0 0 1 1 1 1 CDC45-like protein AAA_11 PF13086.6 KND91875.1 - 0.036 13.8 13.5 0.43 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KND91875.1 - 0.036 13.4 0.4 0.2 11.0 0.0 2.2 2 1 0 2 2 2 0 KaiC TFIIF_alpha PF05793.12 KND91875.1 - 0.053 12.1 29.3 0.084 11.5 29.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_25 PF13481.6 KND91875.1 - 0.078 12.5 0.1 0.29 10.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain Trypan_PARP PF05887.11 KND91875.1 - 0.11 12.4 8.5 0.21 11.6 8.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_16 PF13191.6 KND91875.1 - 0.12 12.8 2.2 0.27 11.6 2.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF755 PF05501.11 KND91875.1 - 0.35 11.1 16.9 0.91 9.8 16.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Zip PF02535.22 KND91875.1 - 0.62 9.2 5.4 0.84 8.8 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 KND91875.1 - 1.4 7.1 23.0 2 6.6 23.0 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 KND91875.1 - 1.4 7.7 10.8 2.2 7.1 10.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dicty_REP PF05086.12 KND91875.1 - 1.4 6.8 6.9 2 6.3 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM60A PF15396.6 KND91875.1 - 1.5 8.8 15.5 2.7 8.0 15.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 KND91875.1 - 2.1 7.1 6.5 3.2 6.5 6.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 KND91875.1 - 2.3 6.9 14.5 3.7 6.2 14.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 KND91875.1 - 2.4 6.6 15.1 3.4 6.1 15.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF2151 PF10221.9 KND91875.1 - 3.1 6.3 10.5 4.5 5.7 10.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Vfa1 PF08432.10 KND91875.1 - 3.5 7.9 23.6 7.1 6.9 23.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 KND91875.1 - 3.6 6.5 8.5 6.5 5.6 8.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 KND91875.1 - 4 5.4 18.5 6.1 4.8 18.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Red1 PF07964.11 KND91875.1 - 4.1 5.5 17.7 6 5.0 17.7 1.1 1 0 0 1 1 1 0 Rec10 / Red1 SAPS PF04499.15 KND91875.1 - 6.9 5.3 15.1 10 4.8 15.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CCDC106 PF15794.5 KND91875.1 - 7.9 6.1 20.3 14 5.3 20.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Neur_chan_memb PF02932.16 KND91875.1 - 9.1 6.3 5.6 19 5.2 5.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFX_C PF14601.6 KND91876.1 - 0.084 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term DUF2470 PF10615.9 KND91877.1 - 0.025 15.2 0.1 0.047 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) Glyco_transf_17 PF04724.13 KND91878.1 - 9.8e-53 179.4 0.0 1.4e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 VESA1_N PF12785.7 KND91879.1 - 2 7.3 12.1 2.2 7.1 12.1 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 ABC_membrane PF00664.23 KND91880.1 - 2e-14 53.9 8.0 2e-14 53.9 8.0 3.1 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND91880.1 - 1.9e-12 47.9 0.1 5e-12 46.5 0.1 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KND91880.1 - 0.0021 17.5 0.1 0.19 11.2 0.0 2.3 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND91880.1 - 0.098 12.4 0.9 0.37 10.6 0.3 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KND91880.1 - 0.12 12.7 0.2 0.24 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND91880.1 - 0.12 11.5 0.2 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 KND91880.1 - 1 8.9 2.9 1.9 8.0 1.3 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zn_clus PF00172.18 KND91881.1 - 9.6e-08 32.0 9.6 1.5e-07 31.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND91881.1 - 2.7e-05 23.3 0.0 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N_2 PF13602.6 KND91882.1 - 1.3e-20 74.8 0.0 2.5e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND91882.1 - 5.7e-12 45.7 0.0 9.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND91882.1 - 0.00025 20.9 0.0 0.0015 18.4 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KND91882.1 - 0.0052 17.2 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KND91882.1 - 0.063 12.7 0.1 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND91882.1 - 0.13 12.2 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 KND91882.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cupin_2 PF07883.11 KND91883.1 - 1e-09 38.0 0.1 1.6e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KND91883.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Cupin U-box PF04564.15 KND91884.1 - 7.6e-18 64.5 0.0 1.4e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 KND91884.1 - 1.1e-09 37.7 3.1 0.063 13.4 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND91884.1 - 1.5e-08 34.1 2.6 0.0022 17.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND91884.1 - 1.9e-08 34.7 3.2 0.00034 21.1 1.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND91884.1 - 1.9e-08 34.1 5.5 5.5e-05 23.3 1.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND91884.1 - 2.5e-05 23.9 1.8 0.012 15.3 0.0 3.0 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 KND91884.1 - 8.1e-05 23.2 4.2 0.045 14.4 1.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND91884.1 - 0.0001 22.8 3.3 0.15 13.0 0.7 3.7 2 1 2 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND91884.1 - 0.0021 18.3 0.7 0.0039 17.4 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KND91884.1 - 0.0089 16.3 0.9 0.022 15.1 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND91884.1 - 0.019 15.3 4.2 0.075 13.3 2.8 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND91884.1 - 0.034 14.2 1.2 10 6.4 0.4 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND91884.1 - 0.039 14.0 0.9 1.3 9.1 0.3 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KND91884.1 - 0.14 12.9 1.7 1.5 9.6 1.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND91884.1 - 0.18 12.5 3.0 0.48 11.2 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 KND91884.1 - 2.6 8.9 10.1 5.9 7.7 10.1 1.6 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPPII_N PF12583.8 KND91885.1 - 1 9.9 9.1 1.4 9.5 9.1 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SET PF00856.28 KND91886.1 - 1.1e-14 55.2 0.9 1.1e-14 55.2 0.9 2.3 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KND91886.1 - 2.8e-07 30.5 6.6 8.8e-07 28.9 6.6 1.8 1 0 0 1 1 1 1 AWS domain FUSC PF04632.12 KND91886.1 - 0.056 12.0 0.2 0.083 11.4 0.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AMP-binding PF00501.28 KND91887.1 - 5.4e-245 812.6 0.0 1.1e-76 258.1 0.1 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 KND91887.1 - 3.8e-168 559.9 0.0 5.9e-47 160.4 0.0 7.3 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.25 KND91887.1 - 4.8e-47 158.2 9.6 3.4e-12 46.5 0.1 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KND91887.1 - 7.3e-07 30.1 0.0 1.6 9.8 0.0 4.9 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain His_Phos_1 PF00300.22 KND91888.1 - 3.8e-33 114.8 0.9 2.7e-31 108.8 0.9 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Zn_clus PF00172.18 KND91890.1 - 3e-08 33.7 8.3 4.5e-08 33.1 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 KND91891.1 - 4.1e-13 49.5 0.0 5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91891.1 - 3.7e-12 46.7 0.0 8.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND91891.1 - 3.1e-11 43.8 0.0 1.2e-10 42.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91891.1 - 2.7e-10 40.2 0.0 7.1e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91891.1 - 3.2e-10 40.7 0.0 5.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND91891.1 - 2.9e-09 36.6 0.0 4.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KND91891.1 - 0.0018 18.3 0.1 0.004 17.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 KND91891.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 KND91891.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 KND91891.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CRAL_TRIO PF00650.20 KND91893.1 - 8.8e-14 51.5 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND91893.1 - 1.5e-05 25.1 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain UCH PF00443.29 KND91894.1 - 2.4e-48 164.9 0.0 3.3e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND91894.1 - 5.1e-14 52.6 2.8 2.5e-13 50.3 2.8 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KND91894.1 - 5e-12 45.4 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KND91894.1 - 0.039 13.8 0.1 0.09 12.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CRA PF06589.11 KND91894.1 - 7.9 6.6 9.6 3.2 7.9 0.9 2.5 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) ARPC4 PF05856.12 KND91895.1 - 3.8e-79 264.1 3.2 4.2e-79 264.0 3.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ALG3 PF05208.13 KND91896.1 - 6.4e-146 486.4 14.8 7.4e-146 486.2 14.8 1.0 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 KND91897.1 - 1.1e-32 114.0 0.7 1.3e-32 113.8 0.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Capsid-VNN PF11729.8 KND91897.1 - 0.035 13.1 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 nodavirus capsid protein NAD_binding_8 PF13450.6 KND91897.1 - 0.038 14.2 0.1 0.092 13.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND91897.1 - 0.046 12.8 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 KND91897.1 - 0.06 12.4 0.1 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KND91897.1 - 0.38 10.0 2.7 0.25 10.5 0.2 2.0 3 0 0 3 3 3 0 Thi4 family MFS_1 PF07690.16 KND91898.1 - 4.5e-22 78.4 87.8 2.6e-17 62.8 52.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD PF12710.7 KND91899.1 - 1.7e-26 93.8 0.0 2.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KND91899.1 - 0.00021 20.9 0.0 0.00049 19.7 0.0 1.6 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KND91899.1 - 0.00024 21.5 0.5 0.004 17.5 0.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KND91899.1 - 0.0055 16.1 0.0 0.33 10.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase CHAT PF12770.7 KND91901.1 - 2.1e-09 37.2 0.0 8.9e-09 35.2 0.0 1.9 2 1 1 3 3 3 1 CHAT domain She9_MDM33 PF05546.11 KND91902.1 - 4.4e-82 274.7 4.8 5.6e-82 274.4 4.8 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1319 PF07028.11 KND91902.1 - 0.042 14.1 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) E3_UbLigase_R4 PF13764.6 KND91902.1 - 0.062 11.5 0.9 0.085 11.0 0.9 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 YscO-like PF16789.5 KND91902.1 - 0.14 12.2 1.7 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 YscO-like protein Tropomyosin_1 PF12718.7 KND91902.1 - 0.22 11.7 4.7 0.3 11.2 0.8 2.2 1 1 1 2 2 2 0 Tropomyosin like Acyl-CoA_dh_1 PF00441.24 KND91903.1 - 3.8e-40 137.5 3.7 7.1e-40 136.6 3.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND91903.1 - 8.7e-30 103.7 0.7 4.1e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND91903.1 - 1.2e-21 76.7 0.0 3.2e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND91903.1 - 9e-18 64.8 1.5 2e-17 63.7 1.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HR1 PF02185.16 KND91904.1 - 1.5e-21 76.3 13.2 3.3e-13 49.6 3.5 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KND91904.1 - 6.4e-19 67.6 32.1 5.9e-12 45.3 11.2 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 KND91904.1 - 8.1e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf-RING_9 PF13901.6 KND91904.1 - 1.8 8.5 22.8 1 9.3 7.9 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Tropomyosin PF00261.20 KND91904.1 - 9.6 5.5 7.6 6 6.2 0.9 2.3 2 0 0 2 2 2 0 Tropomyosin Zn_clus PF00172.18 KND91906.1 - 0.00046 20.3 6.9 0.001 19.1 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 KND91907.1 - 1.2e-23 84.0 0.2 2.3e-23 83.1 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KND91907.1 - 1.4e-07 31.5 0.1 1.9e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KND91907.1 - 0.0052 15.4 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KND91907.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily Zn_clus PF00172.18 KND91908.1 - 2.3e-08 34.0 11.8 3.4e-08 33.5 11.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND91908.1 - 0.00017 20.5 0.4 0.00034 19.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.9 KND91909.1 - 3.2e-07 30.7 0.0 3.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.16 KND91910.1 - 1.7e-27 96.3 22.9 1.7e-27 96.3 22.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_trans PF01144.23 KND91911.1 - 2.1e-91 305.2 0.2 5.8e-54 182.8 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KND91911.1 - 0.00072 19.5 0.1 0.0064 16.4 0.1 2.1 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 KND91911.1 - 0.0059 15.0 0.0 0.011 14.1 0.0 1.3 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter N2227 PF07942.12 KND91912.1 - 2.6e-96 322.0 0.0 3.5e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 KND91912.1 - 0.0034 18.1 0.0 0.015 16.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91912.1 - 0.015 15.9 0.1 0.084 13.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 KND91912.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 KND91913.1 - 1.6e-45 155.5 0.5 2e-45 155.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND91913.1 - 9.7e-42 142.6 0.4 1.4e-41 142.2 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KND91913.1 - 1.3e-11 44.7 0.2 2.4e-11 43.9 0.2 1.4 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 KND91913.1 - 0.084 12.6 1.7 0.86 9.4 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PAC4 PF16093.5 KND91914.1 - 2.8e-17 62.7 0.1 3.7e-17 62.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_EZ PF13513.6 KND91915.1 - 1.3e-30 105.4 12.6 5.7e-16 58.6 0.0 10.4 10 3 2 12 12 11 5 HEAT-like repeat HEAT PF02985.22 KND91915.1 - 1.5e-23 80.8 3.7 0.00028 20.9 0.0 9.7 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 KND91915.1 - 6.6e-14 52.1 0.1 0.00014 22.2 0.0 6.9 5 2 2 7 7 7 4 HEAT repeats IBN_N PF03810.19 KND91915.1 - 9.6e-10 38.2 0.5 6.4e-08 32.4 0.1 4.3 4 1 0 4 4 4 1 Importin-beta N-terminal domain Cnd1 PF12717.7 KND91915.1 - 1.1e-08 35.3 0.0 0.051 13.6 0.0 5.0 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KND91915.1 - 4.6e-07 30.4 0.0 0.15 12.7 0.0 5.9 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KND91915.1 - 2.6e-05 23.9 0.0 14 5.2 0.0 5.7 3 2 2 5 5 5 0 CLASP N terminal MMS19_C PF12460.8 KND91915.1 - 0.00011 21.5 5.4 0.4 9.7 0.0 5.1 6 0 0 6 6 6 2 RNAPII transcription regulator C-terminal Arm PF00514.23 KND91915.1 - 0.00089 19.2 0.7 1.3 9.1 0.0 5.5 6 0 0 6 6 4 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 KND91915.1 - 0.022 14.7 0.7 5 7.1 0.0 4.3 5 0 0 5 5 4 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 KND91915.1 - 0.032 14.4 0.1 12 6.1 0.0 3.7 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KND91915.1 - 0.045 13.5 0.2 35 4.0 0.0 4.5 6 0 0 6 6 6 0 rRNA processing/ribosome biogenesis Telomere_reg-2 PF10193.9 KND91915.1 - 0.21 12.1 0.6 13 6.3 0.0 3.9 4 1 1 5 5 5 0 Telomere length regulation protein HEAT_PBS PF03130.16 KND91915.1 - 0.22 12.3 5.8 6.6 7.7 0.0 5.0 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat OPT PF03169.15 KND91917.1 - 3.6e-178 594.1 61.3 4.1e-178 593.9 61.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.20 KND91917.1 - 1.7 8.1 8.4 0.82 9.2 4.3 2.6 2 0 0 2 2 2 0 E1-E2 ATPase Egh16-like PF11327.8 KND91918.1 - 2.1e-71 240.1 0.5 3.8e-71 239.3 0.5 1.4 1 1 0 1 1 1 1 Egh16-like virulence factor Fungal_trans_2 PF11951.8 KND91919.1 - 3.4e-23 82.1 0.0 2e-22 79.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KND91920.1 - 2.8e-35 121.9 51.8 6.1e-35 120.8 50.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 KND91920.1 - 1.7 7.8 8.5 2.6 7.2 0.1 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter MFS_1_like PF12832.7 KND91920.1 - 3.8 6.2 27.1 0.7 8.7 9.0 2.3 2 1 0 2 2 2 0 MFS_1 like family MAP7 PF05672.11 KND91921.1 - 0.003 17.3 33.8 0.0048 16.6 33.8 1.2 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family eIF-3_zeta PF05091.12 KND91921.1 - 0.22 10.5 6.6 0.32 9.9 6.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1682 PF07946.14 KND91921.1 - 0.29 10.3 18.0 0.44 9.7 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rrn6 PF10214.9 KND91921.1 - 0.43 9.0 9.3 0.64 8.4 9.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NARP1 PF12569.8 KND91921.1 - 0.98 8.2 12.1 1.5 7.6 12.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Exonuc_VII_L PF02601.15 KND91921.1 - 0.98 8.9 9.0 1.5 8.3 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOBP PF15279.6 KND91921.1 - 1.8 9.1 5.9 3.1 8.3 5.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein FemAB PF02388.16 KND91921.1 - 3.6 6.4 12.6 5.1 5.9 12.6 1.1 1 0 0 1 1 1 0 FemAB family DNA_pol_phi PF04931.13 KND91921.1 - 3.8 5.5 11.4 5.2 5.0 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi eIF3_subunit PF08597.10 KND91921.1 - 4.3 7.2 20.5 6.8 6.5 20.5 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDHD PF02862.17 KND91921.1 - 6.8 6.8 5.8 11 6.1 5.8 1.3 1 0 0 1 1 1 0 DDHD domain KilA-N PF04383.13 KND91922.1 - 0.023 14.5 2.1 0.11 12.3 0.0 2.8 2 1 0 2 2 2 0 KilA-N domain HSP70 PF00012.20 KND91922.1 - 1.2 7.3 14.5 1.6 6.9 14.5 1.1 1 0 0 1 1 1 0 Hsp70 protein CDC45 PF02724.14 KND91922.1 - 1.8 6.7 14.4 3.4 5.9 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 KND91922.1 - 5.7 7.0 10.5 0.89 9.6 5.8 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region Rho_GDI PF02115.17 KND91923.1 - 1.6e-64 217.3 0.6 1.7e-64 217.2 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.15 KND91923.1 - 0.064 13.6 0.1 0.076 13.4 0.1 1.1 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain E1_DerP2_DerF2 PF02221.15 KND91923.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 1 0 1 1 1 0 ML domain Metallophos PF00149.28 KND91924.1 - 4.4e-36 125.3 0.4 5.9e-36 124.9 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KND91924.1 - 0.017 15.6 0.2 0.094 13.2 0.2 2.2 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain zf-CCHC PF00098.23 KND91925.1 - 7.2e-06 25.9 1.3 2.2e-05 24.3 1.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 KND91925.1 - 0.024 14.5 0.7 0.15 11.9 0.7 2.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KND91925.1 - 0.16 11.7 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle GEMIN8 PF15348.6 KND91927.1 - 1.8 8.8 14.5 3.6 7.8 14.3 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 FixS PF03597.15 KND91927.1 - 6 6.7 5.2 13 5.6 5.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type RPN2_C PF18004.1 KND91927.1 - 6.7 6.6 14.9 0.5 10.3 10.0 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Exo_endo_phos PF03372.23 KND91929.1 - 0.0012 18.5 0.0 0.0032 17.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_12 PF13424.6 KND91932.1 - 7.1e-22 77.5 15.4 5.3e-11 42.7 0.5 5.3 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KND91932.1 - 9.8e-14 50.7 14.1 8.8e-06 25.4 0.0 6.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 KND91932.1 - 1.3e-06 27.9 1.3 0.026 14.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND91932.1 - 1.3e-05 25.0 0.3 0.38 11.1 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND91932.1 - 0.00012 21.9 8.4 0.25 11.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND91932.1 - 0.00029 20.7 14.6 0.16 12.2 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 KND91932.1 - 0.00034 21.1 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KND91932.1 - 0.00074 18.8 0.2 0.0031 16.7 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KND91932.1 - 0.0009 19.5 0.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.7 KND91932.1 - 0.0018 18.9 0.6 0.006 17.2 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF4477 PF14780.6 KND91932.1 - 0.018 14.7 0.0 14 5.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4477) Hydrolase_4 PF12146.8 KND91932.1 - 0.047 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPR_MalT PF17874.1 KND91932.1 - 0.063 12.6 7.9 0.028 13.8 4.1 2.0 1 1 0 1 1 1 0 MalT-like TPR region MIT PF04212.18 KND91932.1 - 0.12 12.5 0.7 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF676 PF05057.14 KND91932.1 - 0.17 11.3 0.0 0.51 9.8 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) TPR_14 PF13428.6 KND91932.1 - 2.3 9.3 0.0 2.2 9.3 0.1 6.8 8 1 1 9 9 7 0 Tetratricopeptide repeat PaaX_C PF08223.11 KND91933.1 - 0.26 11.6 2.8 3.7 7.9 0.4 2.6 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain SPRY PF00622.28 KND91934.1 - 1.1e-19 70.7 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 SPRY domain AMP-binding PF00501.28 KND91935.1 - 5.5e-26 91.1 0.0 3.1e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KND91935.1 - 1.9e-25 89.5 0.0 2.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KND91935.1 - 2.2e-10 40.4 0.0 5.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KND91935.1 - 5.3e-10 39.5 0.0 1.2e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 KND91935.1 - 0.11 11.6 0.0 3.8 6.5 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KND91935.1 - 0.18 10.9 0.0 0.79 8.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MSP1_C PF07462.11 KND91936.1 - 0.018 13.7 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3918 PF13056.6 KND91936.1 - 0.16 11.6 0.8 0.38 10.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Methyltransf_23 PF13489.6 KND91937.1 - 1.4e-21 77.0 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND91937.1 - 2.6e-14 53.7 0.0 5.7e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND91937.1 - 1.3e-12 48.2 0.0 2.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND91937.1 - 5.9e-12 45.6 0.0 1.6e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND91937.1 - 4.1e-10 40.3 0.0 2.9e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND91937.1 - 1.9e-05 24.2 0.0 7.4e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KND91937.1 - 7.7e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KND91937.1 - 0.00038 20.6 0.0 0.00088 19.4 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KND91937.1 - 0.0005 19.7 0.0 0.0019 17.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KND91937.1 - 0.0011 18.4 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KND91937.1 - 0.0013 18.1 0.0 0.0025 17.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KND91937.1 - 0.023 14.4 0.0 0.059 13.1 0.0 1.6 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_2 PF00891.18 KND91937.1 - 0.18 11.0 0.0 0.48 9.7 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Glyco_hydro_64 PF16483.5 KND91939.1 - 2.6e-123 412.0 0.2 3e-123 411.8 0.2 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF4091 PF13320.6 KND91939.1 - 0.13 12.4 0.1 0.37 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) HD PF01966.22 KND91940.1 - 2.9e-05 24.3 0.0 6.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 HD domain Glyco_hydro_30 PF02055.16 KND91942.1 - 8.2e-37 127.0 0.1 1.1e-36 126.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KND91942.1 - 2.6e-06 27.5 0.0 8.2e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 KND91942.1 - 0.00018 21.2 0.0 0.0004 20.1 0.0 1.5 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 KND91942.1 - 0.00025 20.4 0.1 0.00039 19.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 DUF3050 PF11251.8 KND91942.1 - 0.05 13.2 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Abhydrolase_6 PF12697.7 KND91943.1 - 5.4e-19 69.7 12.2 6.3e-19 69.5 12.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND91943.1 - 0.0011 18.3 0.9 0.014 14.7 0.9 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cellulase PF00150.18 KND91943.1 - 0.043 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Abhydrolase_5 PF12695.7 KND91943.1 - 0.053 13.3 0.0 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 KND91943.1 - 0.066 12.9 0.2 0.18 11.5 0.2 1.6 1 1 1 2 2 2 0 PGAP1-like protein MuF_C PF18819.1 KND91943.1 - 0.23 11.5 0.0 0.44 10.6 0.0 1.4 1 0 0 1 1 1 0 Phage MuF-C-terminal domain Peptidase_S9 PF00326.21 KND91943.1 - 0.24 10.9 1.3 1.3 8.5 0.3 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family BAR PF03114.18 KND91944.1 - 1.1e-47 162.7 4.4 1.3e-47 162.4 4.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KND91944.1 - 4e-06 26.2 1.8 5.3e-06 25.8 1.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KND91944.1 - 0.00077 19.2 0.3 0.0011 18.8 0.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF3086 PF11285.8 KND91944.1 - 0.0053 15.9 0.3 0.0076 15.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) Cyclin_C_2 PF16899.5 KND91945.1 - 3.4e-33 114.1 0.1 4e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 KND91945.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Fungal_trans PF04082.18 KND91946.1 - 0.00031 19.9 0.1 0.00061 18.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF-1a PF01176.19 KND91947.1 - 4.8e-19 67.9 0.1 6.4e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Sugar_tr PF00083.24 KND91948.1 - 1.1e-36 126.7 8.5 1.4e-36 126.4 8.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND91948.1 - 3.7e-09 36.0 16.2 5.5e-09 35.4 16.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND91948.1 - 4.3e-05 23.0 5.2 8.7e-05 22.0 5.2 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KND91948.1 - 0.0071 15.3 4.4 0.015 14.1 4.4 1.5 1 0 0 1 1 1 1 MFS_1 like family Na_Ca_ex PF01699.24 KND91949.1 - 5.1e-10 39.5 5.7 1.2e-09 38.3 5.7 1.6 1 0 0 1 1 1 1 Sodium/calcium exchanger protein NUMOD3 PF07460.11 KND91950.1 - 0.039 14.2 0.2 0.039 14.2 0.2 2.1 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) PTS_IIA PF02255.16 KND91950.1 - 1.8 8.6 8.4 1.2 9.2 2.1 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4355 PF14265.6 KND91950.1 - 5.3 7.3 15.6 3.2 8.0 7.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) MAJIN PF15077.6 KND91950.1 - 6.8 6.4 7.2 9.4 5.9 7.2 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein HSP90 PF00183.18 KND91952.1 - 2.4e-196 653.7 32.3 1.9e-194 647.4 32.3 2.5 1 1 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KND91952.1 - 1.7e-15 57.5 0.1 3.2e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KND91952.1 - 1.4e-09 37.9 0.1 1.4e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KND91952.1 - 0.0036 17.4 3.5 0.13 12.3 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1676) LOH1CR12 PF10158.9 KND91952.1 - 0.28 11.2 3.8 0.12 12.4 0.4 2.1 2 0 0 2 2 2 0 Tumour suppressor protein Tau95 PF09734.9 KND91952.1 - 1.9 9.3 5.9 0.81 10.5 1.7 2.4 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF4695 PF15766.5 KND91952.1 - 2.4 8.4 14.3 0.42 10.9 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4695) Flavin_Reduct PF01613.18 KND91954.1 - 1.3e-35 122.7 0.0 1.5e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Vps5 PF09325.10 KND91955.1 - 5e-88 294.6 4.5 8.4e-88 293.9 4.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KND91955.1 - 1.4e-23 83.0 0.0 3.6e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 KND91955.1 - 0.00034 20.4 6.6 0.03 14.0 1.7 2.6 1 1 1 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 KND91955.1 - 0.0074 15.5 2.0 0.013 14.7 2.0 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KND91955.1 - 0.012 15.3 5.7 0.022 14.4 5.7 1.5 1 0 0 1 1 1 0 BAR domain BAR_3_WASP_bdg PF10456.9 KND91955.1 - 0.021 14.3 0.6 0.045 13.2 0.7 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein DUF713 PF05218.14 KND91955.1 - 0.12 12.1 4.5 0.098 12.4 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF3450 PF11932.8 KND91955.1 - 0.14 11.4 5.4 0.31 10.3 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 KND91955.1 - 0.22 11.7 0.9 0.41 10.8 0.9 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 KND91956.1 - 1.8e-38 129.8 14.9 3.9e-06 27.5 0.3 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KND91956.1 - 4.2e-21 75.5 0.1 8.7e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KND91956.1 - 5.8e-10 39.3 0.0 0.24 11.7 0.0 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KND91956.1 - 0.0008 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 KND91956.1 - 0.0046 16.9 0.0 0.023 14.6 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND91956.1 - 0.011 14.8 0.9 15 4.5 0.0 3.9 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KND91956.1 - 0.19 10.3 0.2 4.1 5.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 AsnC_trans_reg PF01037.21 KND91956.1 - 0.21 11.6 0.0 0.48 10.4 0.0 1.6 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Med11 PF10280.9 KND91957.1 - 2.5e-50 170.5 0.1 3e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Ytp1 PF10355.9 KND91958.1 - 2e-68 230.6 20.5 7e-68 228.8 20.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KND91958.1 - 9.1e-31 105.8 0.3 9.1e-31 105.8 0.3 3.3 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) CBM_2 PF00553.19 KND91959.1 - 0.013 15.8 1.3 0.022 15.1 1.3 1.3 1 0 0 1 1 1 0 Cellulose binding domain MFS_1_like PF12832.7 KND91959.1 - 0.13 11.1 5.7 0.13 11.1 4.4 1.5 1 1 1 2 2 2 0 MFS_1 like family PhyH PF05721.13 KND91960.1 - 7.1e-20 72.2 0.0 1.1e-19 71.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DHHC PF01529.20 KND91962.1 - 3.5e-39 134.0 4.7 3.5e-39 134.0 4.7 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase PI-PLC-X PF00388.19 KND91963.1 - 4.3e-60 201.5 0.0 7.6e-60 200.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KND91963.1 - 5.2e-41 139.6 0.0 1.4e-40 138.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KND91963.1 - 1.3e-05 25.4 0.0 4.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 C2 domain PH_12 PF16457.5 KND91963.1 - 0.011 16.3 0.2 0.082 13.4 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain EF-hand_like PF09279.11 KND91963.1 - 0.11 13.1 0.0 0.3 11.6 0.0 1.9 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like YSIRK_signal PF04650.17 KND91964.1 - 0.21 11.5 0.4 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 YSIRK type signal peptide Zw10 PF06248.13 KND91965.1 - 2.3e-08 33.1 3.1 0.0011 17.6 2.8 2.5 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 CorA PF01544.18 KND91965.1 - 0.35 10.1 4.8 0.59 9.4 4.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF948 PF06103.11 KND91965.1 - 8.3 6.7 6.6 16 5.9 2.0 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TauD PF02668.16 KND91966.1 - 7.8e-46 157.0 0.1 1e-45 156.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 KND91966.1 - 0.027 14.4 0.2 0.053 13.5 0.2 1.4 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY UL16 PF17622.2 KND91966.1 - 0.066 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral unique long protein 16 Transp_cyt_pur PF02133.15 KND91967.1 - 4.5e-25 88.3 30.3 6.4e-25 87.8 30.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0139 PF03669.13 KND91967.1 - 0.039 13.8 0.5 0.16 11.9 0.5 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Pkinase PF00069.25 KND91968.1 - 0.0073 15.7 0.0 0.0081 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KND91969.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain SGL PF08450.12 KND91970.1 - 2e-05 24.3 0.0 0.0044 16.6 0.0 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region ADH_zinc_N PF00107.26 KND91972.1 - 3.6e-14 52.9 0.1 6.6e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND91972.1 - 0.028 14.3 0.0 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 KND91972.1 - 0.055 13.4 0.1 0.089 12.7 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 KND91972.1 - 0.078 12.4 0.3 0.13 11.7 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase APH PF01636.23 KND91973.1 - 2e-08 34.4 0.0 3.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND91973.1 - 0.00066 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase GHMP_kinases_C PF08544.13 KND91976.1 - 1.2e-08 35.2 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal TerB PF05099.13 KND91976.1 - 0.004 17.1 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TerB Ish1 PF10281.9 KND91977.1 - 2e-05 24.8 0.1 2.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Ribosomal_L38e PF01781.18 KND91978.1 - 1.7e-33 114.5 6.4 1.9e-33 114.4 6.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family HAD_2 PF13419.6 KND91979.1 - 1.9e-07 31.3 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND91979.1 - 0.012 15.6 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like LktC PF06261.11 KND91979.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Cupin_1 PF00190.22 KND91980.1 - 2e-36 124.9 0.0 1e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KND91980.1 - 4.8e-22 77.5 0.0 2e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KND91980.1 - 4.3e-06 26.3 0.0 0.0057 16.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KND91980.1 - 2.6e-05 24.1 0.0 0.0044 16.9 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.19 KND91980.1 - 0.00063 19.7 0.0 0.0067 16.3 0.0 2.4 3 0 0 3 3 3 1 AraC-like ligand binding domain 3-HAO PF06052.12 KND91980.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.11 KND91980.1 - 0.01 15.9 0.0 0.51 10.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1971) Glyco_hydro_18 PF00704.28 KND91981.1 - 1.1e-21 77.9 5.1 2.8e-21 76.5 5.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.25 KND91982.1 - 3e-17 62.7 0.0 2e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND91982.1 - 4.1e-08 33.1 0.0 1.1e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND91982.1 - 3.1e-05 24.0 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 KR domain ATLF PF07737.11 KND91982.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Protoglobin PF11563.8 KND91983.1 - 1.6e-58 197.1 0.1 1.9e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Protoglobin PPTA PF01239.22 KND91984.1 - 1.3e-38 129.6 6.4 5.8e-07 29.0 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_8 PF13181.6 KND91984.1 - 0.011 15.9 0.7 0.33 11.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND91984.1 - 0.027 14.5 0.1 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND91984.1 - 0.043 14.3 0.1 1.5 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND91984.1 - 0.08 13.1 1.4 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND91984.1 - 0.097 13.4 0.3 1.2 10.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TIP120 PF08623.10 KND91985.1 - 6.6e-67 224.5 5.4 1.4e-64 216.9 0.0 5.4 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 KND91985.1 - 1.4e-15 57.4 15.5 0.08 13.3 0.4 9.9 7 4 3 10 10 10 5 HEAT repeats Adaptin_N PF01602.20 KND91985.1 - 1.8e-14 53.2 13.1 6e-05 21.8 1.9 6.5 6 1 1 7 7 7 4 Adaptin N terminal region HEAT PF02985.22 KND91985.1 - 2e-11 43.1 24.6 0.5 10.8 0.1 11.0 12 0 0 12 12 11 5 HEAT repeat RTP1_C1 PF10363.9 KND91985.1 - 3.7e-09 36.8 13.4 0.0083 16.3 0.1 6.4 6 1 1 7 7 7 3 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KND91985.1 - 6.7e-09 36.0 12.8 0.0065 16.5 0.1 6.6 7 0 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KND91985.1 - 0.00011 22.7 0.8 6 7.5 0.0 5.8 5 2 1 6 6 5 1 Vacuolar 14 Fab1-binding region VHS PF00790.19 KND91985.1 - 0.0029 17.5 0.1 4.5 7.1 0.0 3.3 3 0 0 3 3 3 2 VHS domain Arm PF00514.23 KND91985.1 - 0.0043 17.0 5.4 18 5.5 0.1 7.2 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KND91985.1 - 0.0052 17.3 17.8 24 5.6 0.0 10.8 12 2 2 14 14 13 0 HEAT-like repeat DUF3361 PF11841.8 KND91985.1 - 0.0072 16.3 14.4 0.69 9.8 0.0 5.5 5 1 0 5 5 5 2 Domain of unknown function (DUF3361) MMS19_N PF14500.6 KND91985.1 - 0.015 14.9 14.7 1.7 8.2 0.6 5.6 5 2 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II RasGEF_N_2 PF14663.6 KND91985.1 - 0.068 13.6 0.8 12 6.3 0.0 4.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3510 PF12022.8 KND91985.1 - 0.073 13.5 0.2 0.3 11.5 0.1 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF3510) RICTOR_N PF14664.6 KND91985.1 - 0.47 9.4 15.3 0.22 10.5 0.9 4.6 6 0 0 6 6 6 0 Rapamycin-insensitive companion of mTOR, N-term MMS19_C PF12460.8 KND91985.1 - 2.9 6.9 20.5 0.57 9.2 0.9 5.3 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal NOA36 PF06524.12 KND91985.1 - 2.9 7.1 12.5 4.7 6.4 12.5 1.2 1 0 0 1 1 1 0 NOA36 protein IPPT PF01715.17 KND91986.1 - 3.5e-62 210.2 0.0 5e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KND91986.1 - 5.4e-06 26.0 0.1 0.0021 17.5 0.0 2.4 2 0 0 2 2 2 2 Isopentenyl transferase AAA_33 PF13671.6 KND91986.1 - 0.00081 19.6 0.5 0.24 11.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.8 KND91986.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.6 KND91986.1 - 0.0031 17.9 0.5 0.01 16.2 0.0 2.1 2 2 0 2 2 2 1 AAA ATPase domain zf-met PF12874.7 KND91986.1 - 0.0032 17.8 0.0 0.0064 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KND91986.1 - 0.13 12.6 0.3 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PhoH PF02562.16 KND91986.1 - 0.18 11.2 0.1 0.6 9.5 0.0 1.9 3 0 0 3 3 3 0 PhoH-like protein zf-U1 PF06220.12 KND91986.1 - 0.28 11.0 1.2 2.6 7.9 0.2 2.5 2 0 0 2 2 2 0 U1 zinc finger DUF87 PF01935.17 KND91986.1 - 0.34 11.0 1.7 2.5 8.1 0.1 2.4 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_membrane PF00664.23 KND91987.1 - 1.2e-55 189.1 23.5 4.1e-33 115.2 4.4 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KND91987.1 - 8.3e-52 175.3 0.0 2.8e-31 108.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND91987.1 - 5.3e-09 35.8 0.3 0.0034 16.8 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KND91987.1 - 3.3e-06 27.8 2.7 0.016 15.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 KND91987.1 - 0.0002 20.6 0.0 0.33 10.0 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KND91987.1 - 0.00047 20.6 0.0 0.15 12.4 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KND91987.1 - 0.00069 19.3 0.6 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KND91987.1 - 0.002 18.2 0.1 0.089 12.9 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND91987.1 - 0.0041 17.0 0.1 3.4 7.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KND91987.1 - 0.0042 16.9 2.8 17 5.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KND91987.1 - 0.0068 16.0 0.1 0.54 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KND91987.1 - 0.012 14.9 0.6 2 7.6 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KND91987.1 - 0.012 15.6 0.0 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KND91987.1 - 0.018 15.3 0.3 8.8 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 KND91987.1 - 0.018 14.7 2.3 7.5 6.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KND91987.1 - 0.02 14.6 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KND91987.1 - 0.023 14.2 0.2 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KND91987.1 - 0.031 14.4 0.3 0.031 14.4 0.3 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain AAA PF00004.29 KND91987.1 - 0.056 13.9 0.7 59 4.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND91987.1 - 0.09 12.5 1.4 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 KND91987.1 - 0.12 12.0 0.9 12 5.5 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 KND91987.1 - 0.14 11.1 4.6 0.96 8.3 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KND91987.1 - 0.15 11.8 0.3 22 4.8 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 KND91987.1 - 0.18 11.5 0.2 0.7 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KND91987.1 - 0.42 10.5 1.8 20 5.1 0.2 2.6 2 0 0 2 2 2 0 NACHT domain Homeodomain PF00046.29 KND91988.1 - 2e-19 69.2 3.1 4.3e-19 68.1 3.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KND91988.1 - 0.0069 16.3 0.5 0.0069 16.3 0.5 2.0 2 0 0 2 2 2 1 Homeobox KN domain NAM-associated PF14303.6 KND91988.1 - 0.48 11.1 6.8 0.82 10.4 6.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Hamartin PF04388.12 KND91988.1 - 5.6 5.5 8.3 7.9 5.0 8.3 1.1 1 0 0 1 1 1 0 Hamartin protein Adaptin_binding PF10199.9 KND91989.1 - 3.8e-14 53.3 7.2 6.4e-14 52.6 7.2 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 ADH_zinc_N_2 PF13602.6 KND91990.1 - 2.8e-16 60.8 0.0 7.3e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND91990.1 - 1.2e-11 44.7 0.2 2.6e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UvdE PF03851.14 KND91991.1 - 3.5e-110 367.6 0.0 5.1e-110 367.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE MutS_IV PF05190.18 KND91991.1 - 0.092 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV HTH_23 PF13384.6 KND91991.1 - 0.12 12.2 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 Homeodomain-like domain Fungal_trans_2 PF11951.8 KND91992.1 - 0.00039 19.4 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KND91993.1 - 0.092 11.8 0.3 0.11 11.5 0.3 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 KND91994.1 - 0.0072 16.4 3.2 0.011 15.8 3.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1694 PF07997.11 KND91994.1 - 0.19 11.8 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Sulfatase PF00884.23 KND91995.1 - 1.2e-26 93.8 0.3 1.7e-26 93.3 0.3 1.2 1 0 0 1 1 1 1 Sulfatase DUF3632 PF12311.8 KND91997.1 - 1.6e-17 64.5 1.0 2.3e-17 64.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) UPF0149 PF03695.13 KND91997.1 - 0.0095 16.2 1.0 1.8 8.8 0.4 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0149) DAO PF01266.24 KND91998.1 - 9.2e-28 97.8 0.0 2.2e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND91998.1 - 5e-05 23.5 0.1 0.00015 21.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KND91998.1 - 0.00018 21.6 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 KND91998.1 - 0.00067 19.0 0.1 0.059 12.6 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 KND91998.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.17 KND91998.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 KND91998.1 - 0.014 14.5 0.1 3.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KND91998.1 - 0.062 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KND91998.1 - 0.11 11.3 0.4 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase KR PF08659.10 KND91998.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 KR domain Sugar_tr PF00083.24 KND91999.1 - 2.6e-31 109.0 1.3 2.9e-31 108.8 1.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Apc13p PF05839.11 KND92000.1 - 7.2e-35 119.1 0.1 9.4e-35 118.7 0.1 1.1 1 0 0 1 1 1 1 Apc13p protein Zn_clus PF00172.18 KND92001.1 - 1.5e-05 25.0 11.1 2.5e-05 24.3 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.20 KND92002.1 - 7.9e-18 64.7 0.0 1.1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Defensin_1 PF00323.19 KND92002.1 - 0.33 11.6 1.4 0.71 10.5 1.4 1.5 1 0 0 1 1 1 0 Mammalian defensin SecY PF00344.20 KND92003.1 - 3.9e-70 236.5 8.1 5.1e-70 236.1 8.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KND92003.1 - 3.4e-17 62.0 0.2 1e-16 60.5 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p PhoLip_ATPase_C PF16212.5 KND92004.1 - 8.2e-72 241.9 21.5 1.4e-71 241.2 21.5 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND92004.1 - 1.4e-22 79.1 0.1 1.7e-20 72.5 0.0 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KND92004.1 - 5.4e-12 46.5 0.1 2.1e-05 24.9 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND92004.1 - 5.3e-11 42.4 0.0 5.8e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KND92004.1 - 9.4e-07 28.5 0.1 2.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND92004.1 - 0.00095 19.0 0.0 0.0024 17.7 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KND92004.1 - 0.039 14.4 0.3 18 5.7 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SnoaL PF07366.12 KND92005.1 - 6e-07 29.3 0.0 8.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KND92005.1 - 0.012 16.2 0.0 0.018 15.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Cupin_3 PF05899.12 KND92007.1 - 0.00046 19.8 0.1 0.00098 18.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 KND92007.1 - 0.03 14.5 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_2 PF07883.11 KND92007.1 - 0.047 13.4 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain CBP_GIL PF10995.8 KND92007.1 - 0.082 11.6 0.0 0.71 8.5 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis GIL DUF676 PF05057.14 KND92008.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND92008.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein ssDNA-exonuc_C PF10141.9 KND92008.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain Cutinase PF01083.22 KND92008.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase PBP_N PF17093.5 KND92008.1 - 1.6 8.9 6.5 4.7 7.5 6.5 1.7 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus BTB PF00651.31 KND92009.1 - 0.00036 20.7 0.0 0.00078 19.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4681 PF15732.5 KND92009.1 - 0.0067 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4681) zinc_ribbon_2 PF13240.6 KND92009.1 - 0.081 12.7 3.8 0.19 11.5 3.8 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Spt4 PF06093.13 KND92009.1 - 0.088 12.9 2.0 0.19 11.8 2.0 1.6 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DUF2076 PF09849.9 KND92012.1 - 0.023 14.7 1.0 0.029 14.4 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.19 KND92013.1 - 2.6e-27 94.6 0.1 5.3e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Clr2_transil PF16761.5 KND92013.1 - 0.1 13.4 0.0 0.24 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 FAD_binding_3 PF01494.19 KND92014.1 - 5.7e-26 91.6 0.0 1e-25 90.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND92014.1 - 2.4e-12 47.1 0.7 2.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND92014.1 - 3.5e-08 33.1 0.1 0.00027 20.3 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KND92014.1 - 7.2e-07 28.8 0.0 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND92014.1 - 3e-06 27.4 0.4 1.7e-05 24.9 0.1 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KND92014.1 - 2.7e-05 23.4 0.0 0.0081 15.2 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Lycopene_cycl PF05834.12 KND92014.1 - 4.1e-05 22.8 0.8 0.046 12.8 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.14 KND92014.1 - 0.00022 20.0 0.0 0.081 11.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 KND92014.1 - 0.00023 21.6 0.0 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND92014.1 - 0.00073 18.7 1.2 0.00084 18.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KND92014.1 - 0.0029 17.6 1.3 0.37 10.8 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KND92014.1 - 0.0037 16.2 0.2 1.9 7.2 0.1 2.8 3 0 0 3 3 3 2 Tryptophan halogenase 3HCDH_N PF02737.18 KND92014.1 - 0.042 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 KND92014.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MLD PF11647.8 KND92014.1 - 0.089 13.1 0.1 3.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Membrane Localization Domain GIDA PF01134.22 KND92014.1 - 0.16 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MHYT PF03707.16 KND92014.1 - 0.41 10.9 1.9 0.71 10.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Adap_comp_sub PF00928.21 KND92015.1 - 5.7e-91 304.5 0.0 7.4e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KND92015.1 - 1e-07 31.9 0.2 1.7e-07 31.3 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SET PF00856.28 KND92016.1 - 3.8e-18 66.5 0.0 1.7e-17 64.3 0.0 2.0 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KND92016.1 - 1.6e-06 28.8 0.8 3.4e-06 27.8 0.8 1.6 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding zf-RING_UBOX PF13445.6 KND92017.1 - 1.3e-05 25.1 1.3 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KND92017.1 - 2e-05 24.8 0.9 0.002 18.4 0.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND92017.1 - 7.1e-05 22.6 0.8 0.0099 15.7 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND92017.1 - 0.00017 21.2 0.5 0.00029 20.5 0.1 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 KND92017.1 - 0.00019 21.6 1.2 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND92017.1 - 0.00049 19.9 0.1 0.0086 15.9 0.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KND92017.1 - 0.0023 18.0 1.4 0.0038 17.4 0.0 1.9 2 0 0 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KND92017.1 - 0.0071 16.0 0.8 0.0095 15.5 0.0 1.5 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KND92017.1 - 0.01 15.9 0.1 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KND92017.1 - 0.018 15.0 0.6 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Rubredoxin PF00301.20 KND92017.1 - 0.029 14.4 0.2 0.088 12.8 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin zf-C3HC4_4 PF15227.6 KND92017.1 - 0.057 13.6 0.8 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Fibrillin_U_N PF18193.1 KND92017.1 - 0.078 13.1 3.6 0.25 11.5 3.6 1.8 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Plasmodium_Vir PF05795.11 KND92017.1 - 0.52 9.7 1.2 0.75 9.1 1.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein E1-E2_ATPase PF00122.20 KND92018.1 - 2.7e-33 115.0 20.6 1.7e-29 102.6 0.3 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KND92018.1 - 3.1e-27 95.4 7.2 3.1e-27 95.4 7.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KND92018.1 - 2.5e-20 73.7 0.0 4.4e-16 59.8 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KND92018.1 - 2.1e-16 59.7 0.0 4.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KND92018.1 - 8.9e-13 47.7 0.0 8.9e-13 47.7 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KND92018.1 - 4.5e-05 23.3 0.2 0.00045 20.0 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 KND92018.1 - 0.41 9.3 6.4 3.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF3435 PF11917.8 KND92019.1 - 1.6e-45 155.8 0.0 1.9e-40 139.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Phage_int_SAM_5 PF13102.6 KND92019.1 - 0.005 17.1 2.6 0.019 15.3 1.9 2.2 2 0 0 2 2 2 1 Phage integrase SAM-like domain YL1 PF05764.13 KND92019.1 - 0.5 10.5 6.9 0.052 13.7 1.3 2.1 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 KND92019.1 - 0.75 8.0 7.2 1.4 7.1 7.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Phage_int_SAM_4 PF13495.6 KND92019.1 - 0.81 10.2 4.0 5.6 7.5 3.8 2.5 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Nop14 PF04147.12 KND92019.1 - 2.4 6.3 12.4 3.3 5.8 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KND92019.1 - 4.6 6.6 12.2 7 6.0 12.2 1.2 1 0 0 1 1 1 0 SDA1 EF-hand_13 PF17958.1 KND92020.1 - 0.029 14.2 0.7 1.4 8.8 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain AbiGi PF10899.8 KND92020.1 - 0.093 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin CwfJ_C_1 PF04677.15 KND92021.1 - 2.9e-29 101.4 0.0 4.5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KND92021.1 - 7.4e-27 94.1 0.1 2.8e-26 92.3 0.1 2.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 KND92021.1 - 0.13 12.7 0.8 5.5 7.5 0.1 2.8 2 0 0 2 2 2 0 Fumarase C C-terminus Trypsin PF00089.26 KND92022.1 - 1.7e-08 34.6 0.2 3e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KND92022.1 - 0.0001 23.2 3.0 0.00021 22.2 3.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Mpv17_PMP22 PF04117.12 KND92023.1 - 3.5e-20 72.0 2.0 4.4e-20 71.7 0.2 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 KND92024.1 - 2.9e-152 507.0 1.0 3.3e-152 506.8 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ADH_zinc_N PF00107.26 KND92024.1 - 0.0036 17.3 0.1 0.1 12.6 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Peripla_BP_4 PF13407.6 KND92024.1 - 0.029 13.9 0.6 0.072 12.6 0.6 1.6 1 0 0 1 1 1 0 Periplasmic binding protein domain FA_hydroxylase PF04116.13 KND92026.1 - 1.4e-08 35.2 3.6 2.1e-08 34.6 3.6 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.20 KND92027.1 - 1.9e-09 37.6 0.0 6.9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND92027.1 - 5.2e-06 25.9 0.0 0.00089 18.6 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DSS1_SEM1 PF05160.13 KND92028.1 - 1.4e-23 82.7 14.4 1.7e-23 82.5 14.4 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 KND92029.1 - 2.3e-122 409.2 0.0 3.3e-122 408.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KND92029.1 - 0.052 14.1 0.6 0.052 14.1 0.6 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KND92029.1 - 0.5 10.7 0.1 0.5 10.7 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND92029.1 - 0.8 9.7 8.7 2 8.4 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND92029.1 - 1.3 9.4 4.0 28 5.3 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND92029.1 - 1.7 9.4 5.7 43 5.0 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Sulfatase PF00884.23 KND92030.1 - 3.3e-14 53.0 0.0 3.9e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Rrp40_N PF18311.1 KND92031.1 - 0.66 10.0 2.8 0.59 10.1 0.9 1.8 1 1 1 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain MFS_1 PF07690.16 KND92032.1 - 3.5e-38 131.4 59.5 3.5e-38 131.4 59.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KND92033.1 - 0.0078 16.3 4.0 0.016 15.3 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfatase PF00884.23 KND92034.1 - 2.1e-21 76.6 0.9 9e-21 74.6 0.9 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KND92034.1 - 2e-08 34.3 0.0 9.3e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 KND92034.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 KND92034.1 - 0.015 14.0 0.0 0.034 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.24 KND92036.1 - 1.6e-08 33.9 0.3 1.9e-08 33.7 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TetR_C_2 PF08361.11 KND92036.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Phage_lysozyme2 PF18013.1 KND92036.1 - 0.078 13.0 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Phage tail lysozyme Cu_bind_CorA PF18252.1 KND92036.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Copper(I)-binding protein CorA DUF1097 PF06496.11 KND92036.1 - 0.37 10.9 4.2 0.56 10.3 4.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) Phosphoesterase PF04185.14 KND92037.1 - 7.3e-75 252.4 7.3 9.9e-75 251.9 7.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 KND92040.1 - 3.5e-35 120.6 0.4 7.8e-34 116.2 0.1 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND92040.1 - 1.9e-32 111.9 4.3 1.7e-29 102.3 0.5 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KND92040.1 - 1.5e-13 51.1 0.0 3.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase MULE PF10551.9 KND92041.1 - 3.9e-18 65.7 0.0 1.2e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 KND92041.1 - 0.00091 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DUF99 PF01949.16 KND92041.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 Tau95 PF09734.9 KND92042.1 - 7.8e-39 133.7 0.2 1.5e-38 132.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KND92042.1 - 4e-35 120.8 0.0 7.4e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain IMUP PF15761.5 KND92042.1 - 4.7 8.0 7.1 7.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein CRAL_TRIO PF00650.20 KND92043.1 - 7.5e-38 129.7 0.0 1.7e-37 128.6 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND92043.1 - 5.4e-13 48.9 1.3 1.4e-12 47.6 1.3 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Exo_endo_phos PF03372.23 KND92043.1 - 1.3e-09 37.9 0.1 2.7e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4748 PF15932.5 KND92044.1 - 2.9e-12 46.1 1.5 7.7e-12 44.8 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 KND92044.1 - 3.4e-09 37.4 0.0 7.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Sds3 PF08598.11 KND92044.1 - 0.045 13.8 9.4 0.1 12.6 9.1 1.6 2 0 0 2 2 2 0 Sds3-like SPX PF03105.19 KND92044.1 - 0.4 10.5 40.9 0.044 13.7 6.7 2.2 2 0 0 2 2 2 0 SPX domain Ribosom_S12_S23 PF00164.25 KND92045.1 - 4.5e-29 100.4 0.8 5.9e-29 100.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 KND92045.1 - 0.18 12.6 0.0 0.41 11.4 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S12 Glyco_transf_15 PF01793.16 KND92046.1 - 4.7e-132 440.2 5.3 5.7e-132 439.9 5.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 KND92047.1 - 0 1329.1 4.4 0 1329.0 4.4 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sin_N PF04801.13 KND92048.1 - 3.4e-19 69.4 0.0 1.9e-09 37.2 0.4 2.3 2 1 0 2 2 2 2 Sin-like protein conserved region TonB_N PF16031.5 KND92048.1 - 2.7 8.5 18.4 0.073 13.6 10.1 2.3 2 0 0 2 2 2 0 TonB polyproline region EMP70 PF02990.16 KND92049.1 - 1.2e-205 684.1 3.7 1.4e-205 683.9 3.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 KND92049.1 - 4.8 6.8 7.1 1.1 8.9 2.9 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Med4 PF10018.9 KND92050.1 - 6.3e-41 140.2 16.6 1.9e-40 138.7 16.6 1.9 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SRP1_TIP1 PF00660.17 KND92050.1 - 0.039 14.0 0.3 0.099 12.7 0.3 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family UDPG_MGDP_dh_C PF03720.15 KND92050.1 - 0.045 14.2 0.3 0.1 13.0 0.3 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AAA_11 PF13086.6 KND92050.1 - 2.4 7.9 9.2 0.4 10.4 3.1 2.0 2 0 0 2 2 2 0 AAA domain Synaphin PF05835.12 KND92050.1 - 3.7 7.8 24.3 0.85 9.9 20.3 1.9 2 0 0 2 2 2 0 Synaphin protein OmpH PF03938.14 KND92050.1 - 10 6.5 17.5 1.6 9.1 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Methyltransf_31 PF13847.6 KND92051.1 - 6.7e-29 100.7 0.0 9e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND92051.1 - 7.1e-24 84.3 0.1 1.6e-23 83.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92051.1 - 8.8e-23 80.8 0.1 1.7e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND92051.1 - 7.3e-18 64.8 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KND92051.1 - 1e-15 58.3 0.1 1.6e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND92051.1 - 1.9e-13 50.6 0.0 2.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KND92051.1 - 3.7e-11 43.0 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KND92051.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 KND92051.1 - 2e-08 33.9 0.0 4.8e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KND92051.1 - 5.6e-07 29.3 0.0 9.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KND92051.1 - 8.6e-06 24.9 0.0 2.6e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 KND92051.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 KND92051.1 - 6.3e-05 22.4 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GidB PF02527.15 KND92051.1 - 0.00062 19.1 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TehB PF03848.14 KND92051.1 - 0.00066 19.1 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 KND92051.1 - 0.0013 17.8 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 KND92051.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 KND92051.1 - 0.017 15.0 0.1 0.078 12.8 0.1 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 KND92051.1 - 0.1 12.1 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NAD_binding_2 PF03446.15 KND92052.1 - 1.5e-38 132.5 1.1 2.1e-38 132.0 1.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KND92052.1 - 5.4e-28 97.7 1.2 5.5e-28 97.6 0.1 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KND92052.1 - 1e-05 26.0 0.0 2.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 KND92052.1 - 9.5e-05 22.6 0.0 0.00017 21.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.15 KND92052.1 - 0.00027 20.0 0.0 0.00042 19.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Ldh_1_N PF00056.23 KND92052.1 - 0.00027 21.0 0.2 0.00058 20.0 0.2 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 KND92052.1 - 0.00029 21.6 0.1 0.0012 19.7 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 KND92052.1 - 0.009 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MTS PF05175.14 KND92052.1 - 0.07 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Jagunal PF07086.12 KND92053.1 - 0.0036 17.4 1.5 0.0075 16.4 0.2 2.0 1 1 1 2 2 2 1 Jagunal, ER re-organisation during oogenesis Actin PF00022.19 KND92054.1 - 1.2e-147 491.8 0.0 4.6e-147 489.9 0.0 1.7 1 1 0 1 1 1 1 Actin Nuf2 PF03800.14 KND92055.1 - 2.1e-41 141.3 1.8 2.1e-41 141.3 0.1 1.9 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 KND92055.1 - 4e-37 126.8 16.7 4e-37 126.8 16.7 4.4 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain RTA1 PF04479.13 KND92057.1 - 2.5e-23 82.8 0.1 3.9e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2754 PF10953.8 KND92057.1 - 0.24 11.7 3.1 0.5 10.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2754) Adaptin_N PF01602.20 KND92058.1 - 6.3e-99 331.9 0.0 7.2e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND92058.1 - 1.5e-17 64.1 0.0 1.2e-15 58.0 0.0 3.1 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND92058.1 - 5.9e-11 42.6 4.2 2.3e-05 24.7 0.0 5.0 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 KND92058.1 - 3.8e-09 36.0 2.5 0.023 14.9 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.7 KND92058.1 - 3.1e-05 24.2 0.8 0.041 14.2 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 KND92058.1 - 0.0029 18.1 5.4 0.16 12.5 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 KND92058.1 - 0.0047 16.5 0.3 7.9 6.0 0.0 3.2 2 1 1 3 3 3 2 CLASP N terminal RRN3 PF05327.11 KND92058.1 - 0.092 11.3 0.0 8 4.9 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 Thioredoxin PF00085.20 KND92059.1 - 1.1e-26 92.8 0.3 1.5e-26 92.4 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KND92059.1 - 5.4e-06 26.8 0.5 2.2e-05 24.9 0.5 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KND92059.1 - 1.4e-05 25.2 0.2 2.6e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KND92059.1 - 0.00017 21.3 0.0 0.00023 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KND92059.1 - 0.00027 20.4 0.3 0.00035 20.0 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KND92059.1 - 0.0013 19.0 0.0 0.004 17.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 KND92059.1 - 0.0015 18.7 0.2 0.0074 16.5 0.1 2.0 1 1 1 2 2 2 1 Glutaredoxin Redoxin PF08534.10 KND92059.1 - 0.0024 17.6 0.4 0.0073 16.0 0.4 1.7 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 KND92059.1 - 0.039 13.8 0.0 0.065 13.0 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 KND92059.1 - 0.13 12.1 0.2 0.45 10.5 0.1 1.7 1 1 1 2 2 2 0 AhpC/TSA family CSN7a_helixI PF18392.1 KND92059.1 - 0.23 11.4 0.1 0.45 10.5 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Sulfatase PF00884.23 KND92061.1 - 3e-55 187.8 0.1 4.8e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KND92061.1 - 0.0059 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) F-box-like PF12937.7 KND92062.1 - 3.3e-05 23.7 0.1 3.3e-05 23.7 0.1 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KND92062.1 - 0.00022 21.0 0.4 0.00091 19.0 0.4 2.1 1 0 0 1 1 1 1 F-box domain GAT PF03127.14 KND92063.1 - 1.6e-17 63.6 0.4 3.3e-17 62.5 0.4 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 KND92063.1 - 2.5e-05 24.2 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 VHS domain MapZ_EC1 PF18041.1 KND92063.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 MapZ extracellular domain 1 Fungal_trans PF04082.18 KND92065.1 - 2.4e-12 46.5 0.7 4.4e-12 45.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92065.1 - 1.4e-08 34.7 15.0 2.7e-08 33.8 15.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KND92065.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat HypA PF01155.19 KND92065.1 - 1.4 9.0 6.3 2.4 8.2 6.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mito_carr PF00153.27 KND92066.1 - 2.8e-59 197.1 0.3 4.7e-22 77.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 KND92066.1 - 0.011 15.8 10.6 0.024 14.8 10.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_holin_3_7 PF05449.11 KND92067.1 - 0.032 14.3 4.7 2 8.5 0.0 2.8 2 1 1 3 3 3 0 Putative 3TM holin, Phage_holin_3 Acetyltransf_1 PF00583.25 KND92069.1 - 1.8e-16 60.4 0.1 2.3e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND92069.1 - 2.3e-10 40.7 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND92069.1 - 8.2e-09 35.5 0.0 1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND92069.1 - 2.1e-07 30.8 0.0 3.9e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 KND92069.1 - 1e-05 25.7 0.0 1.3e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KND92069.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KND92069.1 - 0.0005 20.8 0.0 0.00056 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2856 PF11043.8 KND92069.1 - 0.037 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Acetyltransf_8 PF13523.6 KND92069.1 - 0.063 13.0 0.0 0.095 12.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain UBA_4 PF14555.6 KND92070.1 - 2.7e-10 39.9 0.0 5.9e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KND92070.1 - 1.3e-07 31.7 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Pan3_PK PF18101.1 KND92071.1 - 3.4e-62 208.5 0.1 5.2e-62 207.9 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KND92071.1 - 0.00024 20.6 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 KND92071.1 - 0.029 14.3 0.5 0.056 13.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kdo PF06293.14 KND92071.1 - 0.057 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CorA PF01544.18 KND92072.1 - 4.1e-13 49.3 0.3 7.7e-13 48.4 0.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DivIVA PF05103.13 KND92072.1 - 0.086 12.9 0.1 7.1 6.7 0.1 2.3 2 0 0 2 2 2 0 DivIVA protein RasGAP PF00616.19 KND92073.1 - 2.7e-59 200.4 0.0 1.4e-58 198.1 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KND92073.1 - 1.2e-29 103.2 5.4 1.2e-29 103.2 5.4 2.4 2 0 0 2 2 2 1 RasGAP C-terminus HET PF06985.11 KND92074.1 - 5.6e-23 81.9 0.5 1.3e-22 80.8 0.5 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 KND92075.1 - 2.5e-32 112.2 19.4 2.5e-32 112.2 19.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KND92075.1 - 0.0008 18.8 0.7 0.0008 18.8 0.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4345 PF14248.6 KND92075.1 - 9 6.2 16.0 0.57 10.1 0.8 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4345) Lgl_C PF08596.10 KND92076.1 - 6.2e-123 410.4 0.0 1.1e-122 409.6 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 KND92076.1 - 5.6e-06 27.0 4.4 0.0018 19.1 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92076.1 - 0.0041 17.4 0.0 0.73 10.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KND92076.1 - 0.66 9.5 3.0 65 3.0 0.1 3.6 3 1 0 4 4 4 0 PQQ-like domain Piwi PF02171.17 KND92077.1 - 1.3e-79 267.6 0.0 1.9e-79 267.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KND92077.1 - 9.8e-17 61.9 0.2 2.1e-16 60.8 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KND92077.1 - 7.8e-13 47.9 0.0 4e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KND92077.1 - 4.6e-10 39.4 0.0 9.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KND92077.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KND92077.1 - 2.1e-06 27.9 0.6 9.7e-06 25.8 0.3 2.2 2 0 0 2 2 2 1 Mid domain of argonaute RE_NgoBV PF09564.10 KND92077.1 - 0.034 13.6 0.1 0.068 12.6 0.1 1.4 1 0 0 1 1 1 0 NgoBV restriction endonuclease Suf PF05843.14 KND92078.1 - 7.3e-84 282.2 0.2 7.3e-84 282.2 0.2 4.1 5 1 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KND92078.1 - 0.0028 18.3 3.8 0.025 15.4 0.3 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat HAT PF02184.16 KND92078.1 - 0.025 14.5 0.0 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat HrpJ PF07201.11 KND92078.1 - 0.03 14.6 2.5 2.3 8.5 0.0 3.7 4 0 0 4 4 4 0 HrpJ-like domain PP2C_C PF07830.13 KND92078.1 - 0.17 12.4 0.1 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ASF1_hist_chap PF04729.13 KND92079.1 - 1.1e-70 236.6 0.0 1.5e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone DMSP_lyase PF16867.5 KND92079.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Nop14 PF04147.12 KND92079.1 - 7.6 4.6 19.2 10 4.2 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family APH PF01636.23 KND92081.1 - 1.6e-05 25.0 0.0 1.8e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KND92081.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Fructosamin_kin PF03881.14 KND92081.1 - 0.03 13.5 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.17 KND92081.1 - 0.032 13.5 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase FAD_binding_2 PF00890.24 KND92082.1 - 2e-21 76.6 0.2 2.4e-21 76.3 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND92082.1 - 1.9e-05 24.4 1.2 2.4e-05 24.1 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KND92082.1 - 4.8e-05 22.9 0.7 5.6e-05 22.7 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND92082.1 - 0.00076 18.8 1.2 0.001 18.4 1.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND92082.1 - 0.004 17.3 0.9 0.0066 16.6 0.9 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KND92082.1 - 0.011 14.4 0.5 0.014 14.2 0.5 1.1 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KND92082.1 - 0.015 14.6 0.3 0.02 14.1 0.3 1.1 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 KND92082.1 - 0.038 13.3 1.1 0.05 12.8 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_34 PF11312.8 KND92082.1 - 0.1 11.8 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase RrnaAD PF00398.20 KND92082.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pyr_redox_3 PF13738.6 KND92082.1 - 0.23 10.7 0.6 0.4 9.9 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KND92082.1 - 0.58 9.2 2.3 0.73 8.9 2.3 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KND92083.1 - 0.00012 21.3 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Git3 PF11710.8 KND92084.1 - 4.6e-20 72.3 0.4 4.6e-20 72.3 0.4 2.6 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KND92084.1 - 1.9e-08 34.0 2.7 1.9e-08 34.0 2.7 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 KND92084.1 - 5.6e-05 22.4 2.0 0.0001 21.6 1.9 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 KND92084.1 - 0.00036 20.5 0.1 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term PRIMA1 PF16101.5 KND92084.1 - 0.021 14.8 1.3 0.03 14.3 0.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PBP1_TM PF14812.6 KND92084.1 - 0.063 13.6 3.3 0.15 12.5 3.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIM3 PF17096.5 KND92084.1 - 1.2 10.1 6.2 2.7 9.0 6.2 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DHHC PF01529.20 KND92085.1 - 5.5e-27 94.5 3.1 5.5e-27 94.5 3.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF456 PF04306.13 KND92085.1 - 0.23 11.7 7.5 3.1 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF3810 PF12725.7 KND92085.1 - 0.64 9.3 7.9 3.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) MARVEL PF01284.23 KND92085.1 - 1 9.4 15.2 1.1 9.2 8.5 2.5 2 1 1 3 3 3 0 Membrane-associating domain DUF2897 PF11446.8 KND92085.1 - 1.2 9.1 2.7 3.1 7.8 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2897) DUF1129 PF06570.11 KND92085.1 - 1.2 8.6 4.5 2 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PMT_4TMC PF16192.5 KND92085.1 - 1.4 8.5 6.3 0.12 12.0 0.6 2.0 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase tRNA-synt_1 PF00133.22 KND92086.1 - 1e-194 648.2 0.0 1.5e-194 647.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND92086.1 - 2e-23 83.1 0.0 3.9e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KND92086.1 - 5.8e-16 58.2 0.9 7e-06 25.0 0.2 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KND92086.1 - 7.7e-06 25.5 0.0 0.00015 21.2 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain FAD_binding_2 PF00890.24 KND92088.1 - 6.1e-06 25.6 0.0 7.3e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.7 KND92089.1 - 8.5e-06 25.6 0.6 2.5e-05 24.1 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND92089.1 - 0.027 14.3 1.6 0.083 12.8 1.6 1.9 1 0 0 1 1 1 0 F-box domain RAP1 PF07218.11 KND92090.1 - 0.73 8.0 11.6 1.4 7.1 11.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAD_binding_3 PF01494.19 KND92092.1 - 6.8e-13 48.6 0.1 1.2e-08 34.6 0.1 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KND92092.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FMN_red PF03358.15 KND92093.1 - 1.3e-16 60.8 0.0 1.9e-15 57.0 0.0 2.1 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KND92093.1 - 0.02 14.6 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin-like fold SYS1 PF09801.9 KND92094.1 - 6.9e-48 162.5 5.9 8e-48 162.3 5.9 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Virul_fac_BrkB PF03631.15 KND92094.1 - 2.5 7.6 14.8 14 5.2 14.8 1.8 1 1 0 1 1 1 0 Virulence factor BrkB Lactamase_B_6 PF16661.5 KND92095.1 - 1.4e-62 210.6 0.0 2.1e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KND92095.1 - 4.2e-51 173.5 0.0 4.2e-51 173.5 0.0 2.6 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KND92095.1 - 1.9e-16 60.3 0.0 7.8e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KND92095.1 - 1.3e-14 53.9 0.0 2.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Sec2p PF06428.11 KND92096.1 - 9.6e-29 99.2 21.1 9.6e-29 99.2 21.1 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CENP-Q PF13094.6 KND92096.1 - 0.01 16.1 9.4 0.01 16.1 9.4 3.5 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3584 PF12128.8 KND92096.1 - 0.27 8.7 24.5 0.42 8.1 24.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lar_restr_allev PF14354.6 KND92096.1 - 0.47 10.9 3.3 0.16 12.4 0.3 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar V_ATPase_I PF01496.19 KND92096.1 - 0.52 8.2 9.4 1 7.2 9.4 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 KND92096.1 - 0.76 9.1 14.9 1.7 7.9 14.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 KND92096.1 - 3.5 7.2 21.7 2.4 7.7 0.7 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Tropomyosin_1 PF12718.7 KND92096.1 - 7.2 6.8 28.1 3 8.0 24.4 2.1 1 1 1 2 2 2 0 Tropomyosin like COX6B PF02297.17 KND92097.1 - 8.9e-20 70.7 1.2 1.2e-19 70.3 1.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb PRP21_like_P PF12230.8 KND92098.1 - 8.2e-52 176.2 13.5 1e-50 172.6 13.5 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KND92098.1 - 5.5e-32 109.5 1.2 2.6e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KND92098.1 - 0.025 14.2 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PMT PF02366.18 KND92099.1 - 1.6e-77 260.4 16.1 1.6e-77 260.4 16.1 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND92099.1 - 6.7e-67 225.0 14.4 6.7e-67 225.0 14.4 2.5 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND92099.1 - 3.7e-46 157.3 0.0 8.7e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 MIR domain MFS_1 PF07690.16 KND92100.1 - 4e-16 58.9 83.4 1.5e-13 50.4 48.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily PX PF00787.24 KND92101.1 - 6.3e-24 84.1 0.0 1e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Kri1_C PF12936.7 KND92103.1 - 2.4e-29 101.4 0.0 2.4e-29 101.4 0.0 3.7 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 KND92103.1 - 1.7e-28 99.2 22.3 1.7e-28 99.2 22.3 5.5 7 1 0 7 7 7 1 KRI1-like family Fungal_trans PF04082.18 KND92104.1 - 5.2e-26 91.2 0.0 1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92104.1 - 1.7e-09 37.6 10.9 3.3e-09 36.7 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C50 PF03568.17 KND92105.1 - 7e-166 552.2 0.0 6e-165 549.2 0.0 2.4 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KND92105.1 - 7.7e-11 42.1 10.3 0.0042 17.4 0.0 7.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND92105.1 - 1.3e-05 25.0 8.3 2.3 8.6 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat CHAT PF12770.7 KND92105.1 - 0.00033 20.2 0.4 0.017 14.5 0.0 3.3 3 1 0 3 3 3 1 CHAT domain TPR_19 PF14559.6 KND92105.1 - 0.00093 19.7 8.0 0.35 11.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND92105.1 - 0.0025 18.5 5.4 44 5.3 0.0 7.6 7 1 1 8 8 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KND92105.1 - 0.043 13.5 2.0 0.49 10.1 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 KND92105.1 - 0.051 13.8 8.2 9.2 6.8 0.2 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KND92105.1 - 0.096 12.4 10.1 0.55 9.9 0.4 5.8 5 2 2 7 7 7 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KND92105.1 - 0.49 10.3 2.6 73 3.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KND92105.1 - 1.1 10.1 7.8 1.4e+02 3.5 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND92105.1 - 2.8 7.9 9.2 17 5.4 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SIR2 PF02146.17 KND92106.1 - 1.2e-30 106.8 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.23 KND92107.1 - 3.3e-12 46.5 0.6 4.8e-12 46.0 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND92107.1 - 0.1 13.0 2.2 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 KND92107.1 - 0.11 12.6 0.6 0.2 11.8 0.6 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PI3_PI4_kinase PF00454.27 KND92108.1 - 1.1e-32 113.8 0.0 3.2e-32 112.3 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KND92108.1 - 1.2e-19 70.0 0.0 2.7e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 KND92108.1 - 0.026 13.9 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 KND92108.1 - 0.083 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Ras PF00071.22 KND92110.1 - 1.2e-57 194.0 0.0 1.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND92110.1 - 3.1e-34 117.8 0.0 4.8e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92110.1 - 4e-14 52.4 0.0 6.6e-14 51.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND92110.1 - 2e-06 27.5 0.0 3.6e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KND92110.1 - 7.8e-05 22.7 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND92110.1 - 9.8e-05 21.8 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KND92110.1 - 0.0006 20.2 0.0 0.00085 19.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND92110.1 - 0.055 13.4 0.1 1.8 8.5 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 KND92110.1 - 0.17 12.1 0.0 1.3 9.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain TMEM208_SND2 PF05620.11 KND92111.1 - 1.5e-50 171.3 0.1 1.6e-50 171.1 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF962 PF06127.11 KND92111.1 - 2.8 8.1 5.0 45 4.2 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF962) DUF2530 PF10745.9 KND92111.1 - 8.9 6.6 11.0 19 5.6 11.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) Say1_Mug180 PF10340.9 KND92112.1 - 3.9e-22 78.6 0.0 2.3e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KND92112.1 - 2e-17 63.8 0.0 2.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 KND92113.1 - 3.6e-36 124.8 70.0 1.3e-23 83.6 33.4 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily IPU_b_solenoid PF18783.1 KND92113.1 - 0.36 10.9 0.7 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Isopullulanase beta-solenoid repeat FA_desaturase PF00487.24 KND92114.1 - 1.9e-24 86.9 21.3 1.9e-24 86.9 21.3 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KND92114.1 - 5.1e-06 26.7 0.0 9.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Acid_PPase PF12689.7 KND92115.1 - 9.1e-63 211.1 0.0 1.1e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase CRAL_TRIO PF00650.20 KND92116.1 - 1.7e-23 83.1 0.0 3.4e-23 82.1 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KND92116.1 - 1.6e-10 41.0 0.0 3.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HET PF06985.11 KND92117.1 - 1.1e-18 68.0 0.0 2.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3405 PF11885.8 KND92118.1 - 5.2e-142 474.1 1.0 6.9e-142 473.7 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Cyclin_N PF00134.23 KND92119.1 - 2.2e-09 37.1 0.0 5.3e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Zn_clus PF00172.18 KND92120.1 - 2e-09 37.4 11.2 5.1e-09 36.1 11.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND92120.1 - 0.0023 17.0 1.3 0.0044 16.1 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain IGR PF09597.10 KND92120.1 - 0.16 12.1 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 IGR protein motif Ribosomal_S17e PF00833.18 KND92121.1 - 6.9e-60 200.3 0.3 8.3e-60 200.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KND92122.1 - 6.1e-122 407.7 0.1 7.7e-122 407.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SH3_9 PF14604.6 KND92123.1 - 4.1e-11 42.6 0.6 1e-10 41.3 0.4 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KND92123.1 - 1.7e-09 37.1 0.3 1.7e-09 37.1 0.3 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KND92123.1 - 2.4e-09 36.7 0.0 6.8e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain DNase-RNase PF02577.14 KND92123.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease DNA_pol_phi PF04931.13 KND92123.1 - 0.45 8.6 4.1 0.85 7.6 4.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi GCP_N_terminal PF17681.1 KND92124.1 - 1.1e-29 104.0 0.0 1.8e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KND92124.1 - 9.9e-24 84.4 0.0 5.1e-23 82.0 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF4023 PF13215.6 KND92124.1 - 0.28 11.2 0.5 0.55 10.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Senescence PF06911.12 KND92125.1 - 1.6e-54 185.0 5.5 2.2e-54 184.5 5.5 1.2 1 0 0 1 1 1 1 Senescence-associated protein PIF1 PF05970.14 KND92126.1 - 7.9e-60 202.9 0.1 6.1e-45 154.0 0.0 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KND92126.1 - 5.2e-22 78.5 0.0 1.2e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND92126.1 - 1.2e-11 45.2 0.0 2.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND92126.1 - 3e-07 30.8 0.0 9.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KND92126.1 - 2e-06 27.4 0.0 4.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 KND92126.1 - 6.2e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KND92126.1 - 0.00013 21.8 0.6 0.00041 20.1 0.1 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 KND92126.1 - 0.00035 19.7 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KND92126.1 - 0.00068 20.1 0.0 0.0022 18.4 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 KND92126.1 - 0.00084 17.4 0.1 0.0026 15.8 0.0 1.7 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 KND92126.1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 KND92126.1 - 0.002 17.9 0.1 0.44 10.2 0.0 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KND92126.1 - 0.0046 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 KND92126.1 - 0.0053 16.6 0.0 0.0053 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 KND92126.1 - 0.0054 17.2 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.12 KND92126.1 - 0.01 15.7 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 KND92126.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 KND92126.1 - 0.02 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 KND92126.1 - 0.021 14.9 1.3 5.3 7.1 0.1 2.6 1 1 1 2 2 2 0 Helicase HerA, central domain AAA_14 PF13173.6 KND92126.1 - 0.023 14.8 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND92126.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KND92126.1 - 0.027 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 KND92126.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KND92126.1 - 0.034 13.4 0.0 0.08 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KND92126.1 - 0.051 13.3 0.5 0.09 12.5 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KND92126.1 - 0.055 12.8 0.1 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KND92126.1 - 0.11 11.5 0.1 1.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 KND92126.1 - 0.11 12.5 0.1 0.87 9.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 KND92126.1 - 0.17 11.7 0.0 0.53 10.2 0.0 1.8 2 0 0 2 2 2 0 NTPase PalH PF08733.10 KND92128.1 - 2.2e-111 372.1 0.1 2.6e-111 371.8 0.1 1.1 1 0 0 1 1 1 1 PalH/RIM21 Tox-WTIP PF15654.6 KND92128.1 - 0.17 12.3 3.4 2.1 8.8 0.8 2.7 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif YjeF_N PF03853.15 KND92129.1 - 2.2e-37 128.6 0.1 4.2e-37 127.7 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 KND92129.1 - 9.8e-09 36.0 1.8 9.8e-09 36.0 1.8 2.5 1 1 1 2 2 2 1 FDF domain G-patch_2 PF12656.7 KND92130.1 - 2.9e-19 68.9 1.4 2.9e-19 68.9 1.4 3.3 3 0 0 3 3 3 1 G-patch domain Glyco_transf_28 PF03033.20 KND92131.1 - 1.1e-15 57.9 0.0 6.7e-15 55.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KND92131.1 - 2.6e-05 23.2 0.0 5.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KND92131.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 KND92131.1 - 0.088 13.2 0.0 0.56 10.6 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Na_H_Exchanger PF00999.21 KND92132.1 - 4.5e-73 246.3 41.9 5.5e-73 246.0 41.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myb_DNA-bind_6 PF13921.6 KND92133.1 - 3.1e-15 56.2 0.3 9.6e-15 54.6 0.3 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KND92133.1 - 2.4e-13 50.2 0.1 2.4e-13 50.2 0.1 3.9 4 0 0 4 4 4 1 HSA Myb_DNA-binding PF00249.31 KND92133.1 - 3.6e-05 23.9 0.3 8e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.6 KND92134.1 - 2e-10 40.4 8.4 2.8e-10 39.9 8.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND92134.1 - 7.7e-07 28.9 8.3 1.3e-06 28.1 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KND92134.1 - 8.8e-07 28.7 12.1 1.4e-06 28.0 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND92134.1 - 2.4e-06 27.7 10.2 3.8e-06 27.1 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KND92134.1 - 9.2e-06 25.4 10.1 1.5e-05 24.8 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND92134.1 - 1.1e-05 25.3 10.1 1.8e-05 24.6 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND92134.1 - 7.6e-05 22.6 9.2 0.00016 21.6 9.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KND92134.1 - 0.00017 21.6 5.3 0.00029 20.8 5.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RNHCP PF12647.7 KND92134.1 - 0.00041 20.3 3.0 0.00069 19.5 3.0 1.3 1 0 0 1 1 1 1 RNHCP domain zf-C3HC4_4 PF15227.6 KND92134.1 - 0.006 16.7 8.2 0.01 16.0 8.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KND92134.1 - 0.0092 16.3 6.5 0.018 15.3 6.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KND92134.1 - 0.012 15.4 5.5 0.022 14.5 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KND92134.1 - 0.15 11.8 5.7 0.27 11.0 5.7 1.4 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 KND92134.1 - 3.2 8.0 8.3 2.6e+02 1.9 8.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Nup192 PF11894.8 KND92135.1 - 0 1539.5 0.0 0 1539.3 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 E2F_TDP PF02319.20 KND92135.1 - 0.035 14.2 0.1 0.32 11.1 0.0 2.6 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain Kinetochor_Ybp2 PF08568.10 KND92136.1 - 1.7e-94 317.5 0.0 2.2e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Voltage_CLC PF00654.20 KND92137.1 - 2.9e-87 293.2 23.1 2.9e-87 293.2 23.1 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel NKAIN PF05640.14 KND92137.1 - 0.1 11.8 1.4 0.51 9.5 0.5 2.2 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein Sas10 PF09368.10 KND92138.1 - 7.1e-29 100.1 6.2 7.1e-29 100.1 6.2 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KND92138.1 - 1.4e-10 41.6 0.0 8.5e-10 39.1 0.0 2.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Aminotran_3 PF00202.21 KND92140.1 - 1e-118 396.6 0.0 1.2e-118 396.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KND92140.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Glyco_transf_22 PF03901.17 KND92141.1 - 3e-76 257.3 15.6 4e-76 256.9 15.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BphX PF06139.12 KND92141.1 - 0.03 14.3 0.3 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 BphX-like LigD_N PF13298.6 KND92141.1 - 0.093 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Aminotran_3 PF00202.21 KND92142.1 - 5.5e-118 394.2 0.0 6.6e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 KND92142.1 - 0.00039 19.8 0.0 0.0011 18.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KND92142.1 - 0.0068 15.6 0.0 0.0096 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RhoGAP PF00620.27 KND92144.1 - 1.6e-33 115.7 0.0 3.2e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain BRO1 PF03097.18 KND92145.1 - 5e-07 28.9 0.0 7.4e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Brucella_OMP2 PF05244.11 KND92145.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Brucella outer membrane protein 2 THOC2_N PF16134.5 KND92146.1 - 2.4e-238 792.9 0.0 3.2e-238 792.5 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KND92146.1 - 9.8e-90 300.8 0.0 1.6e-89 300.1 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KND92146.1 - 8.6e-28 96.2 0.2 2e-27 95.1 0.2 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SAS4 PF15460.6 KND92147.1 - 0.053 13.6 0.7 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF1681 PF07933.14 KND92149.1 - 1.1e-56 190.7 0.0 1.4e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CP_ATPgrasp_2 PF14403.6 KND92150.1 - 0.059 12.3 0.1 0.084 11.8 0.1 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 CP_ATPgrasp_1 PF04174.13 KND92150.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 A circularly permuted ATPgrasp SpmSyn_N PF17950.1 KND92150.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal PI-PLC-X PF00388.19 KND92151.1 - 1.4e-07 31.2 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain TMEM61 PF15105.6 KND92152.1 - 0.05 13.4 0.2 0.05 13.4 0.2 1.9 2 0 0 2 2 2 0 TMEM61 protein family DIM PF08194.12 KND92152.1 - 2.9 8.2 3.8 2.8 8.2 1.2 2.2 2 0 0 2 2 2 0 DIM protein RSN1_7TM PF02714.15 KND92153.1 - 1.5e-80 270.4 38.0 1.7e-80 270.3 29.3 2.7 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KND92153.1 - 5.3e-41 140.0 2.3 5.3e-41 140.0 2.3 2.8 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KND92153.1 - 3.7e-36 125.0 0.0 6e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KND92153.1 - 4.5e-33 113.3 0.3 9.8e-33 112.2 0.3 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF2755 PF10954.8 KND92153.1 - 0.062 13.2 1.0 8 6.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) Ribosomal_60s PF00428.19 KND92153.1 - 2.1 9.0 11.6 0.093 13.3 2.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Trp_oprn_chp PF09534.10 KND92158.1 - 0.045 13.6 1.2 0.3 10.8 2.0 1.8 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HKR_ArcB_TM PF18415.1 KND92158.1 - 4.6 8.1 6.6 1.9 9.3 2.3 2.1 1 1 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain ZapB PF06005.12 KND92159.1 - 2.4 8.7 11.1 7.3 7.1 0.0 2.7 2 1 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 KND92159.1 - 3.2 8.5 7.6 1.4 9.5 4.5 2.0 2 1 1 3 3 3 0 Initiation control protein YabA NDUF_B12 PF08122.12 KND92160.1 - 1.9e-08 34.2 4.1 2.2e-08 34.0 0.4 1.9 1 1 1 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family SRI PF08236.11 KND92161.1 - 7e-20 71.0 5.8 2.1e-19 69.4 5.8 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KND92161.1 - 7.5e-17 62.2 3.2 1.2e-16 61.6 0.1 2.8 2 1 0 2 2 2 1 SET domain AWS PF17907.1 KND92161.1 - 2e-10 40.5 6.8 2e-10 40.5 6.8 2.5 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KND92161.1 - 5.3e-05 23.1 1.2 0.00017 21.5 0.1 2.4 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 KND92161.1 - 0.0082 16.2 0.7 0.029 14.5 0.7 2.0 1 0 0 1 1 1 1 WW domain Dehydratase_LU PF02286.15 KND92161.1 - 0.093 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Dehydratase large subunit DUF2431 PF10354.9 KND92162.1 - 3.2e-56 190.2 0.0 8.2e-56 188.9 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Herpes_LMP1 PF05297.11 KND92162.1 - 0.73 9.0 6.3 1.2 8.3 6.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DNA_pol_phi PF04931.13 KND92162.1 - 2.5 6.1 5.5 3.7 5.5 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi ThiF PF00899.21 KND92164.1 - 2.9e-25 89.0 0.0 4.1e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Mhr1 PF12829.7 KND92165.1 - 8e-33 112.4 0.0 1.2e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Rhodanese PF00581.20 KND92166.1 - 3e-08 34.1 0.0 7.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Homeodomain PF00046.29 KND92166.1 - 5.5e-08 32.5 0.0 1.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain PIG-X PF08320.12 KND92167.1 - 6.6e-69 232.0 0.0 9.7e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Patatin PF01734.22 KND92169.1 - 5e-13 49.7 0.0 7.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.25 KND92169.1 - 0.00077 19.3 5.2 0.012 15.4 4.2 2.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND92169.1 - 0.018 15.1 5.4 0.049 13.7 5.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KND92169.1 - 0.026 14.7 6.3 0.15 12.3 1.4 2.9 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KND92169.1 - 0.033 14.1 4.6 0.072 13.0 4.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND92169.1 - 0.068 13.1 5.7 0.15 12.0 5.0 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KND92169.1 - 0.098 12.5 5.8 0.35 10.7 5.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND92169.1 - 0.32 10.9 5.8 0.9 9.5 5.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KND92169.1 - 7.5 7.0 12.2 0.15 12.4 4.5 2.2 3 0 0 3 3 3 0 Ring finger domain Use1 PF09753.9 KND92170.1 - 1.1e-08 35.1 0.0 3.5e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Membrane fusion protein Use1 THOC7 PF05615.13 KND92170.1 - 1.1 9.6 5.0 0.85 9.9 0.1 2.3 2 1 0 2 2 2 0 Tho complex subunit 7 cwf21 PF08312.12 KND92171.1 - 9.6e-18 64.1 15.1 2.4e-17 62.8 15.1 1.7 1 0 0 1 1 1 1 cwf21 domain GvpG PF05120.12 KND92171.1 - 0.00043 20.2 5.9 0.004 17.1 1.5 2.3 2 0 0 2 2 2 2 Gas vesicle protein G MPS2 PF17060.5 KND92171.1 - 0.38 10.0 5.5 0.32 10.2 3.9 1.5 1 1 1 2 2 2 0 Monopolar spindle protein 2 Sugar_tr PF00083.24 KND92172.1 - 1.3e-12 47.4 0.7 2.4e-12 46.5 0.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_47 PF01532.20 KND92173.1 - 1.2e-172 575.0 0.0 1.3e-172 574.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LON_substr_bdg PF02190.16 KND92174.1 - 2.5e-24 86.3 0.0 4.2e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KND92174.1 - 3e-12 46.2 17.3 5.4e-11 42.2 9.7 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND92174.1 - 1e-10 41.3 15.8 6.5e-08 32.3 7.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND92174.1 - 2.5e-09 36.9 16.9 3.4e-07 30.0 9.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND92174.1 - 3e-09 36.7 19.1 5.3e-08 32.8 5.4 3.5 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KND92174.1 - 2.4e-08 33.8 20.8 1e-05 25.4 9.2 2.6 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KND92174.1 - 2.4e-07 31.0 22.5 6.3e-07 29.6 9.9 2.8 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 KND92174.1 - 8.2e-07 29.1 18.0 4.5e-05 23.5 7.6 2.8 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KND92174.1 - 5.5e-06 26.1 15.3 0.00014 21.6 7.2 2.8 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KND92174.1 - 0.00097 18.9 3.9 0.00097 18.9 3.9 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KND92174.1 - 0.012 15.9 5.2 0.012 15.9 5.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 KND92174.1 - 0.071 12.8 10.3 0.025 14.2 5.7 2.4 2 0 0 2 2 2 0 P-11 zinc finger SOCS_box PF07525.16 KND92174.1 - 0.35 11.3 3.6 0.75 10.2 1.8 2.4 2 0 0 2 2 2 0 SOCS box TFIIA PF03153.13 KND92174.1 - 0.48 10.4 8.7 10 6.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_10 PF16685.5 KND92174.1 - 0.57 10.4 13.9 0.082 13.0 6.0 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KND92174.1 - 1.5 8.7 12.3 0.26 11.2 2.6 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Antimicrobial25 PF16839.5 KND92175.1 - 0.051 13.7 1.4 0.11 12.6 1.4 1.5 1 0 0 1 1 1 0 Nematode antimicrobial peptide WD40 PF00400.32 KND92176.1 - 1.7e-08 35.0 0.0 1.2 10.1 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat INSIG PF07281.12 KND92177.1 - 7.8e-87 290.4 0.6 1.3e-86 289.6 0.6 1.4 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) ABC2_membrane PF01061.24 KND92179.1 - 1.6e-26 93.0 28.6 2.4e-26 92.5 28.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KND92179.1 - 3.8e-24 85.8 0.0 5.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KND92179.1 - 2.1e-05 24.5 0.2 0.00034 20.5 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KND92179.1 - 0.00013 22.4 0.1 0.00022 21.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KND92179.1 - 0.0025 17.4 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KND92179.1 - 0.0043 16.9 0.1 3.5 7.3 0.1 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KND92179.1 - 0.0087 16.3 0.1 0.024 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KND92179.1 - 0.0088 16.5 0.0 0.063 13.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND92179.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 KND92179.1 - 0.033 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PDR_CDR PF06422.12 KND92179.1 - 0.052 13.4 1.4 0.6 10.0 0.0 2.8 2 1 0 2 2 2 0 CDR ABC transporter AAA_28 PF13521.6 KND92179.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KND92179.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KND92179.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 KND92179.1 - 0.077 12.8 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KND92179.1 - 0.079 13.0 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 KND92179.1 - 0.12 13.0 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KND92179.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KND92180.1 - 1.8e-41 142.3 0.0 2.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92180.1 - 6.4e-27 94.5 0.0 8.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND92180.1 - 0.0014 18.6 0.5 3.7 7.4 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 KND92180.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KND92180.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SpoVIF PF14069.6 KND92180.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Stage VI sporulation protein F DUF1687 PF07955.11 KND92180.1 - 0.098 13.1 0.3 0.25 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) Tim17 PF02466.19 KND92181.1 - 1.1e-24 86.9 4.9 1.6e-24 86.4 4.3 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PQ-loop PF04193.14 KND92182.1 - 1.9e-34 117.2 16.9 5.7e-18 64.4 0.6 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KND92182.1 - 0.055 14.3 1.2 2.3 9.0 0.1 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor AcrZ PF10766.9 KND92182.1 - 0.3 10.7 4.6 0.22 11.1 0.4 2.5 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ TcpE PF12648.7 KND92182.1 - 1.6 9.3 5.2 2.2 8.8 2.3 2.5 2 1 0 2 2 2 0 TcpE family AAA PF00004.29 KND92184.1 - 1.1e-97 323.5 0.0 1.4e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND92184.1 - 1.9e-24 85.2 3.5 1.1e-12 47.5 0.4 3.5 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KND92184.1 - 8.9e-18 64.2 0.4 3.1e-17 62.5 0.4 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KND92184.1 - 3.3e-14 52.9 0.0 7.2e-06 25.8 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KND92184.1 - 2.1e-13 50.8 0.0 3.6e-07 30.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KND92184.1 - 3.3e-13 50.4 0.0 0.00011 22.7 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 KND92184.1 - 7.4e-12 45.6 0.0 4.7e-05 23.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 KND92184.1 - 9.6e-12 45.1 0.3 4.3e-06 26.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND92184.1 - 3.4e-09 37.1 0.4 0.032 14.5 0.0 3.9 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 KND92184.1 - 4.7e-09 35.9 0.0 0.0015 17.8 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 KND92184.1 - 1.5e-07 31.0 0.1 4.9e-07 29.4 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 KND92184.1 - 2.4e-07 31.4 0.0 0.027 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KND92184.1 - 2.8e-07 30.2 0.2 0.0078 15.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KND92184.1 - 5.4e-07 29.5 0.0 0.022 14.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 KND92184.1 - 8.5e-07 29.3 0.0 0.036 14.4 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 KND92184.1 - 9.8e-07 28.9 0.0 0.0089 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 KND92184.1 - 1.9e-06 27.4 0.4 0.29 10.4 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KND92184.1 - 3.1e-06 26.8 0.0 0.042 13.4 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KND92184.1 - 5.9e-06 26.0 4.5 0.23 11.0 0.1 4.4 3 2 2 5 5 5 2 AAA domain AAA_24 PF13479.6 KND92184.1 - 6.5e-06 26.0 0.0 0.094 12.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 KND92184.1 - 1.2e-05 24.5 0.1 0.059 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KND92184.1 - 2.7e-05 24.5 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 KND92184.1 - 3.4e-05 24.4 0.0 0.31 11.6 0.0 3.6 3 1 0 3 3 2 1 ABC transporter DUF815 PF05673.13 KND92184.1 - 3.6e-05 23.1 0.0 0.049 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KND92184.1 - 3.8e-05 23.5 0.0 0.29 10.8 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.10 KND92184.1 - 7e-05 22.7 0.1 0.00065 19.6 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TsaE PF02367.17 KND92184.1 - 0.00011 22.2 0.0 0.58 10.2 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 KND92184.1 - 0.00011 22.1 0.0 0.26 11.1 0.0 2.6 3 0 0 3 3 2 2 Bacterial dnaA protein NACHT PF05729.12 KND92184.1 - 0.00018 21.5 0.1 0.2 11.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 KND92184.1 - 0.00026 21.0 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 KND92184.1 - 0.00032 20.2 0.3 0.77 9.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.11 KND92184.1 - 0.00033 20.5 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KND92184.1 - 0.00037 20.9 0.0 0.68 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KND92184.1 - 0.00053 19.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KND92184.1 - 0.00061 19.5 0.3 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KND92184.1 - 0.00098 19.1 0.0 2.4 8.0 0.0 3.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2075 PF09848.9 KND92184.1 - 0.0028 17.0 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KND92184.1 - 0.0032 17.8 1.1 6.7 7.0 0.0 3.4 3 1 0 4 4 3 0 AAA domain Sigma54_activ_2 PF14532.6 KND92184.1 - 0.0051 16.9 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 KND92184.1 - 0.0063 15.7 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 KND92184.1 - 0.011 15.4 0.0 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 KND92184.1 - 0.011 15.6 0.6 2.9 7.8 0.0 3.6 4 0 0 4 4 3 0 NTPase IPT PF01745.16 KND92184.1 - 0.017 14.6 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 KND92184.1 - 0.021 14.1 0.5 1.3 8.2 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 KND92184.1 - 0.03 13.6 0.5 9 5.5 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_6 PF12774.7 KND92184.1 - 0.064 12.2 0.1 8.7 5.2 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin PF02224.18 KND92184.1 - 0.079 12.7 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase UFD1 PF03152.14 KND92184.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin2 PF13189.6 KND92184.1 - 0.094 12.8 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 KND92184.1 - 0.11 12.2 0.0 3.4 7.2 0.0 2.8 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.16 KND92184.1 - 0.13 11.1 0.0 14 4.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Rhodanese PF00581.20 KND92185.1 - 3.6e-13 50.0 0.0 1.4e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Myb_DNA-binding PF00249.31 KND92185.1 - 7.2e-09 35.7 0.1 8.2e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 KND92185.1 - 1e-08 34.8 4.3 2e-08 33.9 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KND92185.1 - 1.6e-06 28.3 0.0 5.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ABC_tran PF00005.27 KND92186.1 - 5.7e-16 59.3 0.0 1.9e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KND92186.1 - 0.00032 20.2 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 KND92186.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_21 PF13304.6 KND92186.1 - 0.0033 17.3 0.0 0.037 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KND92186.1 - 0.015 15.7 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KND92186.1 - 0.024 14.9 0.0 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KND92186.1 - 0.039 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 KND92186.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 KND92186.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KND92186.1 - 0.1 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 KND92186.1 - 0.14 12.6 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) LAL_C2 PF18603.1 KND92187.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 DPPIV_N PF00930.21 KND92189.1 - 5.3e-84 282.0 0.3 3.1e-44 151.2 0.0 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KND92189.1 - 4e-56 189.8 1.1 8.7e-56 188.7 1.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KND92189.1 - 0.002 17.8 0.7 0.13 11.8 0.3 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) NB-LRR PF12061.8 KND92189.1 - 0.23 10.8 0.0 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Late blight resistance protein R1 DUF1640 PF07798.11 KND92190.1 - 2.5e-54 183.9 8.9 2.5e-54 183.9 8.9 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) 2-Hacid_dh_C PF02826.19 KND92190.1 - 3.7e-53 179.5 0.0 8.5e-53 178.3 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND92190.1 - 2.1e-18 66.3 0.0 4.2e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND92190.1 - 0.0064 16.7 0.3 0.055 13.6 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase cwf21 PF08312.12 KND92190.1 - 0.1 12.8 1.5 0.26 11.5 1.5 1.7 1 0 0 1 1 1 0 cwf21 domain GNAT_acetyltr_2 PF13718.6 KND92190.1 - 0.1 12.0 0.3 0.23 10.8 0.1 1.6 1 1 1 2 2 2 0 GNAT acetyltransferase 2 DUF5398 PF17376.2 KND92190.1 - 0.63 10.7 2.3 17 6.1 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5398) MFS_1 PF07690.16 KND92191.1 - 1.4e-05 24.2 7.1 1.4e-05 24.2 7.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4537 PF15057.6 KND92191.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) JAB PF01398.21 KND92193.1 - 3.9e-08 33.3 1.0 2.8e-07 30.5 1.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.17 KND92194.1 - 1.4e-128 428.3 0.0 4.3e-74 249.4 0.2 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KND92194.1 - 2.9e-83 277.8 2.0 4.5e-83 277.2 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KND92194.1 - 6e-06 25.7 0.3 1.2e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KND92194.1 - 0.015 14.8 0.4 0.028 14.0 0.4 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 KND92194.1 - 0.051 13.3 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 KND92194.1 - 0.062 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KND92194.1 - 0.079 12.8 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2196 PF09962.9 KND92195.1 - 3.4e-24 84.6 1.6 4.7e-24 84.2 1.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 KND92195.1 - 0.035 14.4 0.6 0.049 13.9 0.6 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 KND92195.1 - 0.23 11.3 0.1 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 GAGA factor Peptidase_M43 PF05572.13 KND92196.1 - 1e-16 61.2 1.9 1.7e-16 60.5 1.2 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KND92196.1 - 5.3e-07 30.0 0.7 1.2e-06 28.8 0.7 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KND92196.1 - 3.2e-05 24.4 0.6 8.9e-05 23.0 0.4 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KND92196.1 - 0.00062 19.5 0.2 0.00085 19.0 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 KND92196.1 - 0.00065 19.8 0.6 0.0013 18.9 0.6 1.5 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 KND92196.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KND92196.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MPTase-PolyVal PF18818.1 KND92196.1 - 0.036 14.1 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Metallopeptidase superfamily domain Metallopep PF12044.8 KND92196.1 - 0.14 10.8 2.2 0.79 8.3 0.8 2.1 2 0 0 2 2 2 0 Putative peptidase family DUF2868 PF11067.8 KND92196.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) ECH_1 PF00378.20 KND92197.1 - 7.8e-13 48.3 0.0 8.6e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND92197.1 - 4.5e-10 39.5 0.0 5.2e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KND92198.1 - 1.2e-25 90.3 0.1 1.4e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND92198.1 - 8.6e-06 25.5 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase KTI12 PF08433.10 KND92199.1 - 2.9e-70 236.8 0.0 5.4e-70 236.0 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KND92199.1 - 0.001 19.2 0.2 0.0025 18.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND92199.1 - 0.0012 19.2 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KND92199.1 - 0.004 17.0 0.0 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KND92199.1 - 0.049 14.2 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KND92199.1 - 0.073 13.4 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KND92199.1 - 0.19 11.8 0.0 0.82 9.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1772 PF08592.11 KND92200.1 - 0.096 13.0 3.3 0.45 10.8 0.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) TMEM208_SND2 PF05620.11 KND92200.1 - 0.16 11.7 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 AAA_2 PF07724.14 KND92201.1 - 4.9e-47 160.2 0.0 3.6e-45 154.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KND92201.1 - 4.1e-32 110.2 15.4 1e-31 108.9 3.5 3.7 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 KND92201.1 - 3.5e-27 95.4 0.0 1.8e-14 54.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KND92201.1 - 1.5e-22 79.4 3.4 1.5e-22 79.4 0.8 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KND92201.1 - 1.4e-15 57.5 0.0 5.1e-10 39.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND92201.1 - 2e-12 47.5 0.0 6.2e-05 23.3 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND92201.1 - 9e-11 42.4 14.6 1.9e-06 28.3 0.1 5.6 4 3 1 6 6 5 2 AAA ATPase domain Sigma54_activat PF00158.26 KND92201.1 - 3.4e-09 36.6 0.0 5.9e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 KND92201.1 - 1e-06 28.8 0.0 0.053 13.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KND92201.1 - 4.1e-06 26.4 0.0 0.017 14.6 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_33 PF13671.6 KND92201.1 - 6.3e-06 26.4 0.2 0.26 11.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND92201.1 - 7e-06 26.6 2.4 0.15 12.6 0.0 4.5 4 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.17 KND92201.1 - 9.2e-06 25.5 0.0 0.082 12.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 KND92201.1 - 2.1e-05 24.6 5.2 0.04 13.8 0.2 4.9 4 1 1 5 5 5 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 KND92201.1 - 3.5e-05 23.3 0.2 0.28 10.5 0.2 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KND92201.1 - 3.6e-05 24.1 0.1 0.37 11.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 KND92201.1 - 8.3e-05 22.9 0.0 0.57 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KND92201.1 - 8.4e-05 22.4 0.0 7.5 6.3 0.0 4.5 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 KND92201.1 - 9.3e-05 22.2 0.1 0.14 11.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 KND92201.1 - 0.0001 22.3 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 KND92201.1 - 0.00012 22.0 0.1 0.89 9.4 0.0 3.9 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 KND92201.1 - 0.00023 21.8 7.3 0.37 11.3 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 KND92201.1 - 0.00028 20.7 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KND92201.1 - 0.00043 20.2 1.3 0.25 11.2 0.0 3.2 3 0 0 3 3 2 1 RsgA GTPase Clp_N PF02861.20 KND92201.1 - 0.0006 19.9 4.8 0.084 13.0 0.1 4.6 4 0 0 4 4 4 1 Clp amino terminal domain, pathogenicity island component ABC_tran PF00005.27 KND92201.1 - 0.0009 19.8 0.5 1.3 9.6 0.0 3.4 3 0 0 3 3 3 1 ABC transporter T2SSE PF00437.20 KND92201.1 - 0.0016 17.6 0.8 0.016 14.2 0.1 2.7 2 1 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 KND92201.1 - 0.0042 17.0 0.0 0.62 10.0 0.0 3.2 3 0 0 3 3 3 1 NACHT domain Torsin PF06309.11 KND92201.1 - 0.0044 17.1 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 1 1 Torsin AAA_19 PF13245.6 KND92201.1 - 0.0046 17.3 3.4 0.5 10.7 0.1 3.9 5 1 0 5 5 3 1 AAA domain AAA_29 PF13555.6 KND92201.1 - 0.005 16.6 0.0 5.3 6.9 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 KND92201.1 - 0.0077 16.2 0.3 6.1 6.7 0.0 2.9 3 0 0 3 3 2 0 Rad17 P-loop domain ResIII PF04851.15 KND92201.1 - 0.008 16.2 0.0 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CbiA PF01656.23 KND92201.1 - 0.0087 16.1 1.3 8.4 6.5 0.9 3.9 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 KND92201.1 - 0.0097 15.2 0.0 1.2 8.3 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 KND92201.1 - 0.013 15.3 0.2 4.5 6.9 0.2 3.3 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KND92201.1 - 0.014 15.6 0.0 4.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KND92201.1 - 0.037 13.9 0.9 0.78 9.6 0.0 3.2 4 0 0 4 4 2 0 NTPase AAA_25 PF13481.6 KND92201.1 - 0.064 12.8 4.1 2.1 7.9 0.0 3.5 3 1 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 KND92201.1 - 0.1 12.4 0.0 9.4 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.19 KND92201.1 - 0.12 10.3 1.7 0.21 9.5 1.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PduV-EutP PF10662.9 KND92201.1 - 0.14 11.9 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Spc7 PF08317.11 KND92201.1 - 0.18 10.6 11.2 0.38 9.6 11.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein OEP PF02321.18 KND92201.1 - 0.29 10.9 11.0 0.68 9.7 11.0 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein Noelin-1 PF12308.8 KND92201.1 - 1.1 9.3 6.0 0.47 10.5 2.6 2.3 2 0 0 2 2 1 0 Neurogenesis glycoprotein Cep57_CLD_2 PF14197.6 KND92201.1 - 1.5 9.0 13.4 0.19 11.8 8.4 2.2 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 Sugarporin_N PF11471.8 KND92201.1 - 2.1 8.4 9.2 1.1 9.3 0.3 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Macoilin PF09726.9 KND92201.1 - 3.1 6.2 7.5 5.4 5.5 7.5 1.3 1 0 0 1 1 1 0 Macoilin family CYSTM PF12734.7 KND92202.1 - 0.0058 16.9 14.2 0.0074 16.6 14.2 1.3 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Zn_clus PF00172.18 KND92203.1 - 2.2e-09 37.2 6.8 2.2e-09 37.2 6.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND92203.1 - 6.5e-07 28.6 0.0 1.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HeLo PF14479.6 KND92204.1 - 1.9e-46 158.5 2.9 2.9e-46 157.9 2.9 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KND92204.1 - 4.4e-05 22.9 0.2 0.00022 20.6 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KND92204.1 - 0.00036 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HCMV_UL139 PF12507.8 KND92204.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3896 PF13035.6 KND92204.1 - 0.14 12.4 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) APH PF01636.23 KND92205.1 - 3.2e-08 33.8 0.0 1.3e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND92205.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND92205.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain adh_short PF00106.25 KND92206.1 - 3.3e-16 59.3 2.4 4.4e-16 58.9 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND92206.1 - 3.9e-12 46.2 1.4 5e-12 45.9 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND92206.1 - 3.1e-06 27.2 0.4 3.1e-06 27.2 0.4 2.1 2 1 1 3 3 3 1 KR domain NmrA PF05368.13 KND92206.1 - 8.5e-06 25.5 3.9 1.5e-05 24.7 3.9 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND92206.1 - 9.5e-05 22.4 1.9 0.00021 21.2 1.9 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND92206.1 - 0.0005 19.6 1.0 0.001 18.6 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KND92206.1 - 0.0043 16.8 1.9 0.14 11.9 0.2 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PALP PF00291.25 KND92206.1 - 0.0076 15.7 3.7 0.048 13.1 3.6 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DapB_N PF01113.20 KND92206.1 - 0.022 14.9 0.3 0.043 13.9 0.3 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 KND92206.1 - 0.03 13.7 0.1 0.03 13.7 0.1 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KND92206.1 - 0.035 13.2 0.6 0.21 10.7 0.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KND92206.1 - 0.18 11.6 1.8 0.26 11.2 1.3 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydro_lipase PF04083.16 KND92207.1 - 6.2e-21 73.8 0.6 1.1e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KND92207.1 - 0.0002 21.1 0.1 0.00084 19.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND92207.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LapA_dom PF06305.11 KND92207.1 - 0.074 12.9 0.4 0.16 11.8 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Chlorophyllase2 PF12740.7 KND92207.1 - 0.15 11.0 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme AAA PF00004.29 KND92208.1 - 4.9e-51 172.6 0.0 2e-43 148.0 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND92208.1 - 3.9e-05 24.1 0.4 0.024 15.0 0.0 3.7 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KND92208.1 - 0.00023 21.0 0.0 0.00069 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 KND92208.1 - 0.00082 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_lid_3 PF17862.1 KND92208.1 - 0.0011 18.7 4.5 0.25 11.2 0.1 3.3 3 0 0 3 3 3 2 AAA+ lid domain AAA_25 PF13481.6 KND92208.1 - 0.0016 18.1 0.1 0.018 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND92208.1 - 0.0031 17.9 0.0 0.043 14.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KND92208.1 - 0.0043 17.2 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KND92208.1 - 0.0064 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KND92208.1 - 0.0086 16.4 0.0 0.041 14.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KND92208.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_5 PF07728.14 KND92208.1 - 0.026 14.5 0.0 0.16 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KND92208.1 - 0.027 13.8 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KND92208.1 - 0.049 13.0 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 KND92208.1 - 0.051 13.7 0.1 0.45 10.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KND92208.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KND92208.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KND92208.1 - 0.095 13.2 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND92208.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KND92208.1 - 0.18 11.8 0.0 0.81 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMS19_N PF14500.6 KND92209.1 - 7e-55 186.4 0.2 2.8e-54 184.4 0.1 2.1 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 KND92209.1 - 1.9e-15 57.0 0.2 4.9e-14 52.3 0.0 3.0 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal PUL PF08324.11 KND92209.1 - 0.044 13.0 0.1 0.14 11.3 0.1 2.0 1 0 0 1 1 1 0 PUL domain AMP-binding PF00501.28 KND92210.1 - 1.6e-99 333.4 0.0 2e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND92210.1 - 3.6e-14 53.5 1.7 4.5e-14 53.2 0.3 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.11 KND92211.1 - 1.1e-102 343.5 0.0 1.3e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein zf-HC2 PF13490.6 KND92211.1 - 1.9 8.8 3.6 19 5.6 0.4 2.8 2 0 0 2 2 2 0 Putative zinc-finger Ribonuclease_T2 PF00445.18 KND92212.1 - 1.9e-44 152.1 1.0 2.7e-44 151.6 1.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SH3BGR PF04908.15 KND92213.1 - 6.7e-05 23.0 0.1 0.00029 21.0 0.0 2.2 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein TFIIA PF03153.13 KND92213.1 - 0.018 15.1 22.8 0.025 14.6 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_P_pop3 PF08228.11 KND92215.1 - 1.1e-06 28.7 0.0 0.00032 20.8 0.0 2.1 2 0 0 2 2 2 2 RNase P subunit Pop3 NOC3p PF07540.11 KND92216.1 - 1.6e-30 105.4 0.9 4.7e-29 100.7 0.4 3.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 KND92216.1 - 1.3e-26 93.6 0.5 3.2e-26 92.4 0.5 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Brix PF04427.18 KND92217.1 - 6.1e-26 91.7 0.1 8.9e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sporozoite_P67 PF05642.11 KND92217.1 - 0.025 12.7 2.0 0.034 12.2 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 KND92217.1 - 0.21 10.9 18.3 0.3 10.4 18.3 1.2 1 0 0 1 1 1 0 BUD22 TPT PF03151.16 KND92218.1 - 6.4e-07 29.0 19.6 1.4e-06 27.9 19.6 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KND92218.1 - 1.1e-05 25.6 14.5 1.1e-05 25.6 14.5 2.7 2 1 0 2 2 2 1 EamA-like transporter family Tuberculin PF12198.8 KND92218.1 - 0.35 11.0 0.1 0.35 11.0 0.1 1.7 2 0 0 2 2 2 0 Theoretical tuberculin protein PRCC PF10253.9 KND92219.1 - 1e-34 121.3 16.5 1e-34 121.3 16.5 2.1 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3517 PF12030.8 KND92221.1 - 1.2e-99 333.5 0.0 2.4e-99 332.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 KND92221.1 - 5.4e-38 131.0 0.1 1e-37 130.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND92221.1 - 2.3e-19 70.1 0.0 4.7e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1981 PF09324.10 KND92221.1 - 0.15 11.9 0.0 9.2 6.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) CTP_synth_N PF06418.14 KND92222.1 - 3.9e-123 410.0 1.5 6.3e-123 409.3 1.5 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KND92222.1 - 2.4e-54 184.0 0.0 3.8e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KND92222.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KND92222.1 - 0.0036 17.3 0.0 0.0045 17.1 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_Rrp7 PF17799.1 KND92223.1 - 0.081 12.7 1.2 0.12 12.2 1.2 1.2 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain Collagen_mid PF15984.5 KND92223.1 - 0.15 11.8 7.7 0.22 11.3 6.9 1.7 1 1 0 1 1 1 0 Bacterial collagen, middle region AI-2E_transport PF01594.16 KND92223.1 - 0.31 10.1 1.3 3.4 6.7 0.3 2.0 1 1 1 2 2 2 0 AI-2E family transporter RIFIN PF02009.16 KND92223.1 - 0.56 10.1 2.8 0.63 9.9 2.8 1.0 1 0 0 1 1 1 0 Rifin DUF2613 PF11021.8 KND92223.1 - 1.3 9.2 8.3 12 6.1 2.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) LPP PF04728.13 KND92223.1 - 1.9 9.0 6.4 0.32 11.4 0.8 2.6 2 1 1 3 3 3 0 Lipoprotein leucine-zipper CRIM PF16978.5 KND92224.1 - 2.8e-42 144.2 0.0 6.3e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KND92224.1 - 3.6e-30 104.5 0.0 7.3e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KND92224.1 - 0.002 18.3 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KND92224.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain TGT PF01702.18 KND92225.1 - 1.8e-140 468.1 0.0 2e-140 467.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MID_MedPIWI PF18296.1 KND92226.1 - 0.03 14.1 0.2 0.03 14.1 0.2 1.5 2 0 0 2 2 2 0 MID domain of medPIWI Pyridoxal_deC PF00282.19 KND92227.1 - 6.8e-74 248.8 0.0 8.9e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KND92227.1 - 2.5e-07 30.3 0.0 4.6e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.19 KND92227.1 - 0.00058 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF4855 PF16147.5 KND92227.1 - 0.14 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) Thioesterase PF00975.20 KND92228.1 - 4.9e-11 43.2 0.0 7.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KND92228.1 - 0.0001 23.0 0.5 0.00013 22.6 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family CENP-F_C_Rb_bdg PF10490.9 KND92228.1 - 0.017 14.5 0.1 0.041 13.3 0.0 1.7 1 1 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 Abhydrolase_2 PF02230.16 KND92228.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KND92228.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold bZIP_1 PF00170.21 KND92229.1 - 0.00055 20.0 4.1 0.0013 18.8 4.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KND92229.1 - 0.014 15.4 3.4 0.029 14.4 3.4 1.5 1 0 0 1 1 1 0 Basic region leucine zipper ABC_tran PF00005.27 KND92231.1 - 5.2e-49 166.3 0.7 4.3e-26 92.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KND92231.1 - 4.2e-25 88.6 31.4 5.6e-15 55.3 19.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KND92231.1 - 5.6e-21 75.6 6.0 2.7e-05 24.1 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND92231.1 - 3.3e-09 36.3 0.2 0.005 16.6 0.3 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 KND92231.1 - 8.4e-07 28.6 5.7 0.29 10.6 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KND92231.1 - 1.8e-05 25.4 1.9 0.1 13.1 0.3 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KND92231.1 - 0.00045 20.2 1.5 0.59 10.0 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 KND92231.1 - 0.00086 19.1 0.3 1.6 8.4 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 KND92231.1 - 0.008 15.9 1.5 1.1 8.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KND92231.1 - 0.025 15.0 1.3 8 6.8 0.0 3.0 3 1 0 3 3 2 0 AAA ATPase domain AAA_27 PF13514.6 KND92231.1 - 0.03 13.9 0.4 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KND92231.1 - 0.051 13.8 0.5 19 5.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KND92231.1 - 0.057 13.7 0.2 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 KND92231.1 - 0.11 12.5 1.1 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 KND92231.1 - 0.13 12.7 0.1 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KND92231.1 - 0.15 12.0 0.0 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KND92231.1 - 0.17 11.1 0.2 29 3.9 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 KND92231.1 - 0.3 10.7 1.2 17 4.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Hist_deacetyl PF00850.19 KND92232.1 - 8e-54 183.2 0.0 1.1e-53 182.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PHP PF02811.19 KND92233.1 - 6e-12 46.2 0.0 1.6e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 PHP domain HAD_2 PF13419.6 KND92234.1 - 4e-08 33.6 0.0 5.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND92234.1 - 0.00022 21.6 0.0 0.0011 19.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DFP PF04127.15 KND92234.1 - 0.022 14.6 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Solute_trans_a PF03619.16 KND92235.1 - 7.3e-83 278.1 26.3 8.6e-83 277.9 26.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WSC PF01822.19 KND92236.1 - 1.2e-10 41.5 9.4 1.2e-10 41.5 9.4 1.8 2 0 0 2 2 2 1 WSC domain Gram_pos_anchor PF00746.21 KND92236.1 - 0.0013 18.6 0.8 0.0013 18.6 0.8 2.3 2 0 0 2 2 2 1 LPXTG cell wall anchor motif Podoplanin PF05808.11 KND92236.1 - 0.0055 16.8 8.9 0.01 16.0 8.9 1.4 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 KND92236.1 - 0.0061 16.4 0.0 0.0061 16.4 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KND92236.1 - 0.011 15.7 6.0 0.22 11.4 6.0 2.4 1 1 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 KND92236.1 - 0.04 13.3 1.6 0.11 11.9 1.6 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4366 PF14283.6 KND92236.1 - 0.067 13.2 0.0 0.26 11.3 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 KND92236.1 - 0.21 10.9 0.6 0.45 9.9 0.1 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF5305) SR-25 PF10500.9 KND92236.1 - 9.1 5.8 11.6 19 4.7 11.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Afaf PF15339.6 KND92237.1 - 0.21 11.3 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor TRAM_LAG1_CLN8 PF03798.16 KND92238.1 - 2.4e-37 128.6 13.3 3.9e-37 127.9 13.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KND92238.1 - 1.6e-25 88.5 0.0 3.5e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein PCRF PF03462.18 KND92240.1 - 0.12 12.3 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 PCRF domain SPX PF03105.19 KND92240.1 - 0.41 10.5 10.5 0.12 12.3 6.5 1.9 2 0 0 2 2 2 0 SPX domain Sugar_tr PF00083.24 KND92242.1 - 8.1e-40 137.0 11.4 2.1e-39 135.7 11.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND92242.1 - 6.8e-16 58.1 25.0 1.8e-15 56.8 24.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KND92243.1 - 1.7e-46 158.9 0.0 4.1e-46 157.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND92243.1 - 0.012 16.2 3.6 0.017 15.8 2.8 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sulfotransfer_3 PF13469.6 KND92244.1 - 1.7e-06 28.6 0.0 2.6e-05 24.7 0.0 2.5 1 1 0 1 1 1 1 Sulfotransferase family AbiEii PF08843.11 KND92247.1 - 0.0023 18.0 0.1 0.0025 17.8 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system Methyltransf_2 PF00891.18 KND92248.1 - 7.8e-22 77.6 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain fn3_5 PF06280.12 KND92249.1 - 0.35 11.6 5.1 13 6.5 0.1 3.3 3 1 1 4 4 4 0 Fn3-like domain NYN PF01936.18 KND92250.1 - 0.018 15.5 0.2 0.047 14.2 0.1 1.7 1 1 0 1 1 1 0 NYN domain DUF3435 PF11917.8 KND92251.1 - 0.014 14.4 0.0 0.014 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) 2OG-Fe_Oxy_2 PF10014.9 KND92252.1 - 3.1e-50 170.7 0.7 3.1e-50 170.7 0.7 1.8 2 0 0 2 2 2 1 2OG-Fe dioxygenase AMP-binding PF00501.28 KND92253.1 - 1.1e-64 218.6 0.0 1.4e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND92253.1 - 5.6e-17 62.5 0.1 1.3e-16 61.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldolase_II PF00596.21 KND92254.1 - 8.2e-42 143.2 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PI-PLC-X PF00388.19 KND92256.1 - 1.6e-05 24.5 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_2_C PF02836.17 KND92256.1 - 0.032 13.3 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain APH PF01636.23 KND92257.1 - 4.2e-09 36.7 0.0 9.1e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND92257.1 - 0.0033 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KND92257.1 - 0.07 12.4 0.0 0.2 10.9 0.0 1.7 1 1 1 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 KND92257.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 KND92257.1 - 0.3 9.9 0.0 0.44 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Hpt PF01627.23 KND92258.1 - 3.1e-11 43.4 0.0 4.9e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Catalase-rel PF06628.12 KND92258.1 - 0.046 13.9 0.0 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Catalase-related immune-responsive Sad1_UNC PF07738.13 KND92259.1 - 8e-06 25.9 0.0 0.005 16.9 0.1 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal QCR10 PF09796.9 KND92259.1 - 0.045 13.8 0.5 0.094 12.8 0.5 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SelB-wing_2 PF09106.11 KND92259.1 - 0.076 13.2 0.4 25 5.2 0.2 2.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF3180 PF11377.8 KND92259.1 - 0.085 13.0 3.2 0.054 13.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) BMFP PF04380.13 KND92259.1 - 1.1 9.8 4.8 8.7 6.9 4.8 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity DUF4217 PF13959.6 KND92260.1 - 7.4e-18 64.5 0.0 2e-17 63.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) GAGA_bind PF06217.12 KND92260.1 - 0.11 12.8 3.9 0.19 12.0 3.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DEAD PF00270.29 KND92261.1 - 1.8e-46 158.1 0.0 3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND92261.1 - 5.7e-26 91.0 0.0 5.5e-25 87.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND92261.1 - 1.1e-07 32.0 0.0 2.5e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KND92261.1 - 0.03 13.7 4.7 0.75 9.1 0.0 2.5 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KND92261.1 - 0.064 13.5 0.1 0.66 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain RGS PF00615.19 KND92262.1 - 0.0032 17.7 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain ECH_1 PF00378.20 KND92263.1 - 8.9e-34 116.9 0.0 1.1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND92263.1 - 1.1e-08 35.0 0.2 3.5e-08 33.3 0.3 1.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Epimerase PF01370.21 KND92264.1 - 2e-15 56.9 0.2 5.3e-15 55.5 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND92264.1 - 2.4e-09 37.0 0.5 4.5e-09 36.2 0.5 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KND92264.1 - 8e-07 29.1 2.8 9.6e-07 28.9 1.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND92264.1 - 1.5e-05 24.2 0.3 2e-05 23.7 0.3 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KND92264.1 - 0.0079 15.4 0.1 0.031 13.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 KND92264.1 - 0.03 13.9 0.4 0.049 13.2 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KND92264.1 - 0.11 12.0 1.2 1.2 8.7 1.2 2.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NUC153 PF08159.12 KND92265.1 - 6.3e-15 54.7 0.9 6.3e-15 54.7 0.9 3.6 4 0 0 4 4 4 2 NUC153 domain AMP-binding PF00501.28 KND92266.1 - 7.4e-65 219.2 0.1 1.6e-64 218.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND92266.1 - 0.0001 23.2 0.0 0.00028 21.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SPC12 PF06645.13 KND92266.1 - 0.55 10.4 3.5 0.31 11.2 0.6 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cytochrom_B561 PF03188.16 KND92266.1 - 0.94 9.6 6.3 2.3 8.4 0.7 2.5 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Zn_clus PF00172.18 KND92267.1 - 0.0019 18.2 9.7 0.0054 16.8 9.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KND92268.1 - 7.4e-149 496.2 0.0 1.1e-148 495.6 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KND92268.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) EBP PF05241.12 KND92270.1 - 3.3e-46 157.0 10.8 8.9e-46 155.6 10.8 1.6 1 1 0 1 1 1 1 Emopamil binding protein Nup88 PF10168.9 KND92271.1 - 7.3e-08 30.7 0.2 6.6e-05 20.9 0.0 2.5 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 KND92271.1 - 0.0021 18.1 6.9 0.031 14.4 5.9 2.4 1 1 1 2 2 2 2 Nucleoporin complex subunit 54 Cep57_CLD PF14073.6 KND92271.1 - 8.1 6.4 11.2 0.36 10.8 5.2 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 RRM_1 PF00076.22 KND92272.1 - 3.2e-16 58.9 0.0 4.5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 KND92273.1 - 7.8e-46 154.7 0.7 8.7e-46 154.5 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.21 KND92273.1 - 0.034 15.0 0.6 0.046 14.5 0.6 1.1 1 0 0 1 1 1 0 H-NS histone family CENP-T_C PF15511.6 KND92275.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KND92275.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KND92275.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KND92275.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KND92275.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KND92275.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KND92275.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KND92275.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KND92275.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Aminotran_1_2 PF00155.21 KND92276.1 - 9.6e-38 130.3 0.0 1.4e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND92276.1 - 4.4e-07 28.8 0.0 6.1e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND92276.1 - 0.00074 18.6 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND92276.1 - 0.0058 16.0 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Mannitol_dh_C PF08125.13 KND92277.1 - 1e-39 136.5 0.3 1.8e-39 135.7 0.3 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KND92277.1 - 5.3e-19 68.9 0.2 1.7e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain PGI PF00342.19 KND92278.1 - 9.8e-225 746.7 0.6 1.2e-224 746.4 0.6 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase_C PF00433.24 KND92278.1 - 0.029 15.1 0.2 0.12 13.1 0.2 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 KND92279.1 - 2.5e-08 34.2 0.1 2.9e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KND92279.1 - 1.7e-06 27.6 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND92279.1 - 8.5e-05 22.0 0.1 9.6e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 KND92279.1 - 0.0009 18.2 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 KND92279.1 - 0.0013 18.3 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KND92279.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Ribosomal_S21 PF01165.20 KND92280.1 - 4e-08 32.9 5.8 6.2e-08 32.2 5.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PRCC PF10253.9 KND92280.1 - 0.062 14.1 2.7 0.077 13.8 2.7 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 KND92280.1 - 8.4 5.5 7.7 9.3 5.3 7.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HAUS6_N PF14661.6 KND92281.1 - 7.8e-56 189.2 0.1 1.5e-55 188.2 0.1 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Trypan_PARP PF05887.11 KND92281.1 - 5.2 7.0 14.3 2.4 8.1 7.3 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KND92281.1 - 8.9 5.4 10.6 0.28 10.3 1.1 2.1 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 DUF4419 PF14388.6 KND92282.1 - 1.1e-91 307.4 0.0 1.3e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Acetyltransf_6 PF13480.7 KND92282.1 - 0.035 14.3 0.6 0.081 13.1 0.6 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_35 PF01301.19 KND92283.1 - 0.063 12.9 0.2 0.52 9.9 0.1 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases family 35 HSDR_N_2 PF13588.6 KND92283.1 - 0.12 12.4 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Coatomer_WDAD PF04053.14 KND92284.1 - 4.6e-169 563.2 0.0 9e-169 562.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KND92284.1 - 1.3e-38 130.3 9.3 8.5e-06 26.4 0.0 9.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92284.1 - 8.1e-09 35.7 0.1 4 7.8 0.0 6.2 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND92284.1 - 5.6e-05 22.0 2.7 0.055 12.1 0.1 4.0 1 1 4 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KND92284.1 - 0.019 15.0 0.0 17 5.5 0.0 3.6 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 KND92284.1 - 0.078 13.2 0.0 0.23 11.7 0.0 1.8 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Vps54 PF07928.12 KND92285.1 - 4.3e-48 163.2 0.0 1.1e-47 161.8 0.0 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2451 PF10474.9 KND92285.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KND92285.1 - 0.00025 20.5 1.2 0.00025 20.5 1.2 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Sec8_exocyst PF04048.14 KND92285.1 - 0.11 12.4 1.5 1 9.2 1.2 2.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 KND92285.1 - 0.31 9.9 4.1 1 8.2 0.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DSPc PF00782.20 KND92287.1 - 5.4e-09 36.0 0.0 1.4e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KND92287.1 - 0.0029 17.9 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF2375 PF09558.10 KND92287.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) Ribonuclease_3 PF00636.26 KND92288.1 - 2.5e-44 150.2 0.1 4.8e-21 75.4 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KND92288.1 - 9.4e-28 96.9 0.0 2.6e-11 43.8 0.0 3.7 2 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KND92288.1 - 1.9e-20 72.8 0.1 6.8e-19 67.8 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 KND92288.1 - 4.3e-18 65.7 1.0 1.7e-17 63.7 0.3 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND92288.1 - 1.5e-14 54.3 0.0 4.2e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND92288.1 - 1.7e-13 50.7 0.0 4.1e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Mqo PF06039.15 KND92288.1 - 0.0015 17.1 0.0 0.072 11.6 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) AAA_22 PF13401.6 KND92288.1 - 0.013 15.8 0.1 0.11 12.8 0.0 2.7 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 KND92288.1 - 0.015 14.5 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase dsrm PF00035.26 KND92288.1 - 0.11 13.3 0.1 0.47 11.2 0.0 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif SWI2_SNF2 PF18766.1 KND92288.1 - 0.12 12.1 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Tam41_Mmp37 PF09139.11 KND92289.1 - 1.7e-127 425.3 0.0 2.1e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial MAD PF05557.13 KND92290.1 - 9.6e-64 215.9 64.6 5.7e-63 213.4 64.4 1.9 1 1 0 1 1 1 1 Mitotic checkpoint protein Cation_efflux PF01545.21 KND92291.1 - 2e-31 109.3 1.5 3.3e-31 108.6 1.5 1.3 1 0 0 1 1 1 1 Cation efflux family DUF4551 PF15087.6 KND92291.1 - 0.83 8.4 1.7 1 8.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NACHT PF05729.12 KND92293.1 - 5e-12 46.1 0.0 8.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KND92293.1 - 2.4e-06 27.9 0.0 5.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND92293.1 - 0.00016 22.1 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 KND92293.1 - 0.0094 16.1 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Torsin DUF2075 PF09848.9 KND92293.1 - 0.065 12.5 0.0 0.097 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 KND92293.1 - 0.13 11.5 0.2 4.9 6.3 0.1 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA PF00004.29 KND92293.1 - 0.17 12.3 0.0 0.45 10.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cwf_Cwc_15 PF04889.12 KND92294.1 - 4.4e-73 246.0 29.5 5.9e-72 242.4 29.5 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3381 PF11861.8 KND92294.1 - 0.068 13.0 17.5 0.18 11.6 17.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 KND92294.1 - 1.4 7.2 17.8 1.6 6.9 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 KND92294.1 - 3.7 6.0 10.9 4.4 5.7 10.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FGGY_C PF02782.16 KND92295.1 - 2.1e-19 70.0 0.0 3.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KND92295.1 - 1.7e-14 54.0 0.0 1.3e-05 24.9 0.0 3.5 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 KND92296.1 - 1.1e-14 54.6 0.3 1.3e-14 54.4 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KND92296.1 - 0.00012 22.1 0.1 0.00026 21.1 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Arf PF00025.21 KND92297.1 - 8.3e-40 136.1 0.0 1.4e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KND92297.1 - 1.7e-13 50.4 0.0 1.5e-08 34.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KND92297.1 - 2.7e-08 34.1 0.0 5.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KND92297.1 - 4e-08 32.9 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KND92297.1 - 9.2e-08 31.9 0.0 2.1e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 KND92297.1 - 2.2e-07 30.5 0.0 4.6e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KND92297.1 - 0.00063 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND92297.1 - 0.0026 17.3 0.0 0.009 15.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DsbC PF11412.8 KND92297.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Disulphide bond corrector protein DsbC RNase_PH PF01138.21 KND92298.1 - 2.1e-18 67.1 0.0 3.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND92298.1 - 1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Glyco_hydro_18 PF00704.28 KND92299.1 - 8.5e-69 232.7 4.7 1.2e-68 232.2 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_2 PF12796.7 KND92300.1 - 1.3e-22 80.2 0.0 6.1e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND92300.1 - 1.7e-17 63.3 0.0 3.2e-07 30.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KND92300.1 - 7.8e-17 61.4 0.0 2.5e-07 31.1 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND92300.1 - 2.5e-16 58.1 0.0 0.00015 21.9 0.0 4.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KND92300.1 - 1.4e-15 56.9 0.0 6.7e-05 23.2 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat DUF1771 PF08590.10 KND92301.1 - 7.2e-25 87.2 8.7 1.5e-24 86.2 8.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KND92301.1 - 5.3e-10 39.5 1.1 2e-09 37.7 0.3 2.3 2 0 0 2 2 2 1 Smr domain DUF4407 PF14362.6 KND92301.1 - 0.01 15.2 3.0 0.015 14.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G-alpha PF00503.20 KND92302.1 - 4.9e-122 407.5 1.1 6e-122 407.2 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KND92302.1 - 1.2e-14 54.2 2.0 6.9e-10 38.6 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 KND92302.1 - 0.00019 21.2 0.1 0.00041 20.1 0.1 1.5 1 0 0 1 1 1 1 CHC2 zinc finger Gtr1_RagA PF04670.12 KND92302.1 - 0.0091 15.4 2.6 0.51 9.7 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 KND92302.1 - 0.017 14.8 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KND92302.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 KND92302.1 - 0.13 12.4 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KND92302.1 - 0.15 11.6 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KND92302.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KND92302.1 - 0.18 11.9 0.1 9.5 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3716 PF12511.8 KND92303.1 - 1.5e-09 37.8 0.3 2.8e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Pex14_N PF04695.13 KND92303.1 - 0.021 15.5 11.1 0.021 15.5 11.1 3.8 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0121 PF03661.13 KND92304.1 - 9.7e-30 103.7 0.6 1.5e-29 103.1 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.20 KND92304.1 - 2.3e-10 40.4 0.0 4.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KND92304.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KND92304.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family WD40 PF00400.32 KND92305.1 - 1.9e-56 186.7 9.3 6e-09 36.4 1.5 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92305.1 - 1.6e-10 41.2 0.3 0.00049 20.3 0.1 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND92305.1 - 0.0007 18.4 0.6 0.17 10.5 0.0 3.7 4 0 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KND92305.1 - 0.0093 14.8 0.1 3.3 6.4 0.0 2.5 3 0 0 3 3 3 2 Nup133 N terminal like DUF3632 PF12311.8 KND92307.1 - 1.1e-27 97.7 0.1 1.4e-27 97.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Nudix_N PF12535.8 KND92307.1 - 0.42 10.2 1.7 0.92 9.2 0.2 2.4 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal Peptidase_S10 PF00450.22 KND92309.1 - 2.3e-78 264.5 0.0 7.7e-78 262.8 0.0 1.8 2 1 0 2 2 2 1 Serine carboxypeptidase Peptidase_M28 PF04389.17 KND92311.1 - 2.5e-38 131.8 0.2 1.7e-37 129.1 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KND92311.1 - 0.0038 16.9 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3328 PF11807.8 KND92312.1 - 4.2e-31 108.4 2.8 1.4e-30 106.7 2.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Herpes_gE PF02480.16 KND92312.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4179 PF13786.6 KND92312.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) ICE2 PF08426.10 KND92312.1 - 0.24 10.5 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 ICE2 Acetyltransf_10 PF13673.7 KND92313.1 - 0.097 12.6 0.3 0.35 10.8 0.0 2.0 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain CDK2AP PF09806.9 KND92313.1 - 0.13 12.3 0.5 0.17 11.9 0.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Acetyltransf_1 PF00583.25 KND92313.1 - 0.14 12.4 0.3 0.19 12.0 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family D123 PF07065.14 KND92314.1 - 3.2e-114 381.2 0.0 3.7e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 D123 AMP-binding PF00501.28 KND92315.1 - 0 2245.7 0.0 6.3e-79 265.5 0.0 10.3 10 0 0 10 10 10 10 AMP-binding enzyme Condensation PF00668.20 KND92315.1 - 0 1637.1 0.0 1.7e-55 188.5 0.0 12.3 11 1 1 12 12 12 12 Condensation domain PP-binding PF00550.25 KND92315.1 - 3.1e-116 379.8 20.2 1.4e-09 38.2 0.1 11.8 11 0 0 11 11 11 11 Phosphopantetheine attachment site DUF4569 PF15133.6 KND92315.1 - 0.018 14.8 0.0 32 4.1 0.0 4.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4569) Evr1_Alr PF04777.13 KND92316.1 - 5.8e-27 94.1 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Proteasome PF00227.26 KND92317.1 - 7.5e-45 152.8 0.1 8.5e-45 152.6 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4139 PF13598.6 KND92318.1 - 2.2e-28 99.4 0.0 4.1e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KND92318.1 - 3.5e-23 81.9 0.6 4.1e-22 78.5 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) GLTSCR1 PF15249.6 KND92318.1 - 0.38 11.2 2.3 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein DUF5345 PF17280.2 KND92318.1 - 0.96 9.5 4.3 1.8 8.6 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3450 PF11932.8 KND92318.1 - 2.9 7.1 8.9 0.89 8.8 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) RPAP2_Rtr1 PF04181.13 KND92319.1 - 2.5e-20 72.6 0.0 3.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF3364 PF11844.8 KND92319.1 - 0.081 13.2 0.0 19 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3364) TFIIA PF03153.13 KND92320.1 - 0.15 12.1 5.0 0.27 11.2 5.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 KND92320.1 - 0.92 9.1 6.7 1.4 8.5 6.7 1.1 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 KND92320.1 - 2.6 7.1 7.5 4.5 6.4 7.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3543 PF12063.8 KND92323.1 - 1.2e-91 306.6 0.0 2e-91 305.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KND92323.1 - 1e-55 188.9 0.0 9.8e-54 182.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND92323.1 - 3.1e-36 125.0 0.0 2.3e-35 122.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KND92323.1 - 0.06 12.3 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ribosomal_L41 PF05162.13 KND92326.1 - 1.1e-11 44.5 29.0 1.2e-11 44.4 29.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 RNA_pol_I_A49 PF06870.12 KND92327.1 - 4.4e-99 331.9 0.2 5.2e-99 331.7 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zeta_toxin PF06414.12 KND92328.1 - 1.3e-41 142.1 0.1 3.8e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 KND92328.1 - 1.6e-07 31.6 0.9 3.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zn_clus PF00172.18 KND92328.1 - 0.0011 19.0 5.1 0.0019 18.2 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TsaE PF02367.17 KND92328.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KND92328.1 - 0.093 13.0 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ECH_1 PF00378.20 KND92329.1 - 4.5e-23 81.8 0.0 6.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND92329.1 - 4.6e-13 49.4 0.0 5.5e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Vps51 PF08700.11 KND92330.1 - 1.7e-12 47.2 0.1 6.5e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 DUF1283 PF06932.11 KND92330.1 - 0.017 15.3 1.7 4.5 7.6 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) Nexin_C PF08628.12 KND92330.1 - 0.089 13.4 0.4 0.28 11.8 0.1 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal MFS_1 PF07690.16 KND92331.1 - 6.6e-43 147.0 28.2 6.7e-40 137.1 19.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KND92331.1 - 0.0025 16.2 5.4 0.044 12.1 1.4 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KND92331.1 - 2.4 6.9 16.0 0.92 8.3 4.8 3.3 3 1 1 4 4 4 0 MFS_1 like family DUF2841 PF11001.8 KND92332.1 - 1.9e-42 144.2 3.7 2.9e-42 143.6 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Sec34 PF04136.15 KND92332.1 - 0.044 13.7 0.1 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family HLH PF00010.26 KND92333.1 - 7.9e-13 48.2 0.3 1.6e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 KND92333.1 - 0.024 14.8 1.8 0.27 11.3 1.8 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term AAA_28 PF13521.6 KND92333.1 - 0.062 13.5 0.4 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fungal_trans_2 PF11951.8 KND92333.1 - 0.15 10.8 0.2 0.21 10.4 0.2 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Pox_A30L_A26L PF06086.12 KND92333.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein CLTH PF10607.9 KND92335.1 - 5.5e-28 97.7 0.0 1.4e-27 96.4 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KND92335.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 LisH NUDIX PF00293.28 KND92336.1 - 6.3e-19 68.3 0.1 1.3e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KND92336.1 - 2.7e-12 47.2 0.0 8.5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KND92336.1 - 1.7e-08 33.9 0.8 3e-08 33.2 0.8 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Cnd1 PF12717.7 KND92337.1 - 0.0031 17.6 3.3 0.08 13.0 0.9 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KND92337.1 - 0.015 15.5 0.7 3.3 8.2 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Nop52 PF05997.12 KND92337.1 - 0.16 11.7 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 0 Nucleolar protein,Nop52 DUF2682 PF10909.8 KND92337.1 - 2 8.9 4.0 16 6.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) DUF3384 PF11864.8 KND92337.1 - 6.3 5.6 13.9 1 8.2 0.0 3.4 2 2 0 3 3 3 0 Domain of unknown function (DUF3384) DUF1749 PF08538.10 KND92338.1 - 1.3e-82 277.3 0.0 1.4e-82 277.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KND92338.1 - 1.1e-09 39.3 0.0 1.3e-09 39.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND92338.1 - 3e-07 29.9 0.0 2.1e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND92338.1 - 4.5e-06 26.5 0.0 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KND92338.1 - 0.027 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DLH PF01738.18 KND92338.1 - 0.14 11.7 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family ABC_membrane PF00664.23 KND92339.1 - 2.8e-89 299.4 32.2 6.2e-50 170.4 8.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND92339.1 - 9.9e-48 162.1 0.0 2e-30 106.1 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND92339.1 - 3.3e-08 33.2 3.8 0.0061 16.0 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KND92339.1 - 1.2e-05 25.4 0.7 0.18 11.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND92339.1 - 0.00017 21.5 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KND92339.1 - 0.0021 18.5 0.4 0.088 13.2 0.3 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KND92339.1 - 0.0025 17.5 0.2 1.1 9.0 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KND92339.1 - 0.0036 17.4 1.8 0.13 12.4 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 KND92339.1 - 0.019 14.8 0.2 8.9 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KND92339.1 - 0.053 13.6 3.1 0.7 9.9 0.1 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 KND92339.1 - 0.098 12.3 0.2 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 KND92339.1 - 0.11 12.9 0.0 5.7 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KND92339.1 - 0.14 12.4 0.3 51 4.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KND92339.1 - 0.16 12.5 0.3 30 5.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KND92339.1 - 0.37 10.7 2.2 0.99 9.3 0.1 2.6 3 0 0 3 3 3 0 NACHT domain AIG1 PF04548.16 KND92339.1 - 0.72 9.1 2.1 4.9 6.4 0.1 2.4 2 0 0 2 2 2 0 AIG1 family CAF1 PF04857.20 KND92340.1 - 1e-20 74.2 0.0 9.7e-10 38.1 0.1 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KND92340.1 - 0.14 12.8 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain APH PF01636.23 KND92342.1 - 0.0033 17.4 0.1 0.6 10.0 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family p450 PF00067.22 KND92343.1 - 4.2e-51 174.1 0.0 5.6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_5 PF13873.6 KND92343.1 - 0.13 12.3 0.4 22 5.2 0.1 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Acetyltransf_1 PF00583.25 KND92344.1 - 3.4e-13 49.8 0.0 7.2e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND92344.1 - 1.5e-11 44.4 0.0 4.9e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND92344.1 - 7.1e-11 42.4 0.0 1.3e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND92344.1 - 7.9e-07 29.2 0.1 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND92344.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein RRP7 PF12923.7 KND92344.1 - 0.039 14.1 0.6 0.089 12.9 0.5 1.6 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Acetyltransf_CG PF14542.6 KND92344.1 - 0.051 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PRIMA1 PF16101.5 KND92345.1 - 1.2 9.2 12.9 4.4 7.4 4.1 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Cullin PF00888.22 KND92347.1 - 6.8e-169 563.4 0.0 2.2e-168 561.7 0.0 1.9 2 0 0 2 2 2 1 Cullin family PI3_PI4_kinase PF00454.27 KND92347.1 - 1.2e-50 172.6 0.0 2.4e-50 171.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KND92347.1 - 1.1e-47 162.0 0.0 1.1e-47 162.0 0.0 3.2 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair Cullin_Nedd8 PF10557.9 KND92347.1 - 2e-15 56.6 3.6 2.9e-15 56.1 0.2 3.0 3 0 0 3 3 3 1 Cullin protein neddylation domain FAT PF02259.23 KND92347.1 - 6.3e-10 38.8 6.4 1.3e-09 37.8 6.4 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 KND92347.1 - 3.3e-07 30.0 0.1 8.1e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain FliS PF02561.14 KND92347.1 - 0.00091 19.5 0.1 0.0065 16.7 0.0 2.5 2 0 0 2 2 2 1 Flagellar protein FliS DUF2262 PF10020.9 KND92347.1 - 0.033 14.6 0.1 0.6 10.5 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) Fer2_3 PF13085.6 KND92348.1 - 2.5e-33 114.3 0.0 3.9e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KND92348.1 - 1.2e-08 35.3 6.3 1.2e-08 35.3 6.3 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KND92348.1 - 4.7e-08 33.0 2.9 4.7e-08 33.0 2.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KND92348.1 - 2.5e-07 31.0 9.1 2.5e-07 31.0 9.1 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 KND92348.1 - 0.0016 18.3 3.0 0.0031 17.4 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 KND92348.1 - 0.0048 17.5 5.9 0.0048 17.5 5.9 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 KND92348.1 - 0.0092 16.2 0.5 0.42 10.8 0.2 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.8 KND92348.1 - 0.015 15.9 0.9 0.17 12.4 0.3 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 KND92348.1 - 0.57 10.4 13.3 2.9 8.1 10.7 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Nup188_C PF18378.1 KND92350.1 - 4.6e-161 535.8 1.9 7.1e-161 535.1 1.9 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KND92350.1 - 2.1e-39 135.2 2.1 1.4e-32 112.6 1.8 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 KND92351.1 - 2.7e-92 308.5 0.0 4e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KND92351.1 - 2.8e-49 167.5 0.0 8.8e-48 162.6 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.22 KND92351.1 - 1e-47 162.4 0.3 1.9e-42 145.2 0.0 2.8 2 1 0 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KND92351.1 - 5.5e-06 26.3 0.1 1.6e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 KND92351.1 - 0.035 13.9 0.3 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.18 KND92351.1 - 0.046 12.7 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase zf-C3HC4_3 PF13920.6 KND92352.1 - 0.0076 16.1 4.2 0.011 15.5 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 KND92352.1 - 0.09 12.6 5.6 0.14 12.0 5.6 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type PTCB-BRCT PF12738.7 KND92353.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.26 KND92353.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Methyltransf_2 PF00891.18 KND92354.1 - 4.1e-20 72.0 0.1 3.8e-18 65.6 0.1 2.3 1 1 0 1 1 1 1 O-methyltransferase domain SPOUT_MTase PF02590.17 KND92354.1 - 0.21 11.5 0.0 0.76 9.7 0.0 1.8 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Phage_holin_2_4 PF16082.5 KND92355.1 - 0.00072 19.2 0.5 0.0087 15.8 0.2 2.5 2 0 0 2 2 2 1 Bacteriophage holin family, superfamily II-like PRCH PF03967.13 KND92355.1 - 0.61 10.3 2.0 1 9.6 0.1 2.2 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region SARAF PF06682.12 KND92355.1 - 1.2 8.7 9.7 1.1 8.8 4.3 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis CMAS PF02353.20 KND92356.1 - 1.1e-62 211.8 0.0 1.4e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KND92356.1 - 9e-11 41.9 0.0 2.1e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND92356.1 - 2.7e-10 40.7 0.0 5.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92356.1 - 7.8e-10 39.3 0.0 1.7e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND92356.1 - 0.00046 20.9 0.0 0.001 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND92356.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KND92356.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KND92356.1 - 0.059 13.4 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KND92356.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KND92356.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Phosphodiest PF01663.22 KND92357.1 - 4.4e-14 52.9 0.0 8.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND92357.1 - 9.6e-05 21.9 0.0 0.00043 19.8 0.0 1.8 2 1 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KND92357.1 - 0.0076 15.6 0.3 0.016 14.6 0.3 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily MaoC_dehydratas PF01575.19 KND92358.1 - 4.1e-07 29.6 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain SUIM_assoc PF16619.5 KND92359.1 - 0.36 10.9 0.1 0.36 10.9 0.1 2.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 7TM_GPCR_Sru PF10322.9 KND92360.1 - 0.17 11.2 0.2 0.23 10.7 0.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru NACHT PF05729.12 KND92361.1 - 4.6e-06 26.6 0.7 4.3e-05 23.5 0.4 2.8 2 1 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.7 KND92361.1 - 1.5e-05 25.7 0.0 3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 KND92361.1 - 2.1e-05 25.0 0.0 7.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND92361.1 - 8.4e-05 22.9 0.0 0.00089 19.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF676 PF05057.14 KND92361.1 - 8.8e-05 22.1 0.0 0.00026 20.6 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND92361.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_30 PF13604.6 KND92361.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KND92361.1 - 0.044 14.2 0.1 1.5 9.2 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KND92361.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KND92361.1 - 0.049 14.0 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 KND92361.1 - 0.061 12.6 0.0 0.81 8.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain KorB_C PF06613.11 KND92361.1 - 0.086 12.8 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain NB-ARC PF00931.22 KND92361.1 - 0.12 11.5 0.0 0.6 9.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 KND92361.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Synaptobrevin PF00957.21 KND92362.1 - 1.3e-30 105.0 0.3 1.8e-30 104.5 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KND92362.1 - 1.3e-28 98.8 0.1 2.6e-28 97.9 0.0 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain SUV3_C PF12513.8 KND92363.1 - 6.6e-15 54.8 1.0 1.8e-14 53.4 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KND92363.1 - 1.4e-12 47.2 0.2 3.4e-12 46.0 0.2 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 KND92363.1 - 8e-09 35.8 0.0 2.2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ADC PF06314.11 KND92364.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Cyclin PF08613.11 KND92365.1 - 1.8e-40 138.9 1.0 1.6e-25 90.4 0.1 3.4 4 1 0 4 4 4 2 Cyclin Spt20 PF12090.8 KND92365.1 - 2 7.9 0.0 2 7.9 0.0 3.4 3 1 0 3 3 3 0 Spt20 family Beta_elim_lyase PF01212.21 KND92366.1 - 2.8e-62 210.6 0.0 3.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KND92366.1 - 4.1e-06 25.6 0.0 8.4e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KND92366.1 - 0.00012 21.4 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND92366.1 - 0.0006 18.9 0.0 0.00095 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KND92366.1 - 0.002 17.5 0.0 0.0066 15.8 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Tyrosinase PF00264.20 KND92367.1 - 1.8e-48 165.8 2.0 3.3e-48 164.9 2.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 KND92367.1 - 2.4e-30 105.7 0.0 4e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_transf_17 PF04724.13 KND92371.1 - 4.9e-46 157.4 0.0 1.2e-45 156.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 HTH_Tnp_ISL3 PF13542.6 KND92371.1 - 0.058 12.8 0.6 0.16 11.4 0.6 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 YbjQ_1 PF01906.17 KND92372.1 - 2.6e-24 85.9 0.2 3.1e-24 85.6 0.2 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding RNA_pol_Rpb2_6 PF00562.28 KND92373.1 - 1.1e-110 370.4 0.1 1.6e-110 369.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KND92373.1 - 1.8e-33 115.7 0.0 3e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KND92373.1 - 6.3e-28 96.8 0.0 2.4e-27 94.9 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 KND92373.1 - 2.7e-25 89.1 0.0 4.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 KND92373.1 - 2.3e-24 85.2 0.0 5.4e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 KND92373.1 - 4.5e-17 62.2 0.0 1.4e-15 57.4 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 DZR PF12773.7 KND92373.1 - 0.14 12.2 1.2 0.27 11.3 1.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF570 PF04489.13 KND92373.1 - 0.15 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Clathrin PF00637.20 KND92374.1 - 7e-200 654.9 36.0 1e-31 109.7 1.7 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KND92374.1 - 1.6e-34 116.5 0.1 2.5e-07 30.7 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KND92374.1 - 4.8e-32 109.7 2.0 1.2e-31 108.4 0.4 2.7 3 0 0 3 3 2 1 Clathrin-H-link TPR_14 PF13428.6 KND92374.1 - 5.8e-05 23.6 9.8 11 7.2 0.0 7.9 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND92374.1 - 7.3e-05 22.5 5.4 10 6.4 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KND92374.1 - 0.00032 19.9 7.5 0.11 11.6 0.2 4.7 5 0 0 5 5 5 2 Coatomer WD associated region TPR_8 PF13181.6 KND92374.1 - 0.0018 18.4 7.8 0.25 11.6 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND92374.1 - 0.0044 17.3 1.5 11 6.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat 6PF2K PF01591.18 KND92374.1 - 0.012 14.9 0.1 0.053 12.8 0.1 2.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPR_1 PF00515.28 KND92374.1 - 0.021 14.6 5.5 1.8 8.5 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 KND92374.1 - 0.067 13.1 0.8 21 5.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB PQQ_2 PF13360.6 KND92374.1 - 0.076 12.6 0.0 6.1 6.3 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain TPR_19 PF14559.6 KND92374.1 - 0.1 13.1 3.3 14 6.3 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND92374.1 - 0.54 10.5 11.3 1.9 8.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat NifU_N PF01592.16 KND92375.1 - 4.4e-49 165.9 0.2 1.6e-42 144.7 0.0 2.0 1 1 1 2 2 2 2 NifU-like N terminal domain MR_MLE_N PF02746.16 KND92375.1 - 0.067 13.4 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DNApol_Exo PF18136.1 KND92376.1 - 4.1e-105 351.0 0.0 6.9e-105 350.2 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KND92376.1 - 1.2e-55 189.2 0.0 1.8e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 KND92376.1 - 0.089 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Voltage_CLC PF00654.20 KND92377.1 - 1.1e-86 291.4 27.7 1.1e-86 291.4 27.7 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel DUF2545 PF10810.8 KND92377.1 - 0.72 10.0 0.0 0.72 10.0 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2545) LacI PF00356.21 KND92377.1 - 0.84 9.5 1.9 1.9 8.3 1.9 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family PT-VENN PF04829.13 KND92377.1 - 6.2 7.0 5.1 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Neurochondrin PF05536.11 KND92378.1 - 2.1e-93 313.8 2.1 2.6e-93 313.5 2.1 1.0 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 KND92378.1 - 0.0018 18.0 2.9 0.0027 17.5 0.3 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 KND92378.1 - 0.018 14.9 0.2 0.096 12.6 0.2 2.2 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NopRA1 PF16201.5 KND92378.1 - 0.056 13.0 0.7 18 4.9 0.0 3.3 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 ATP-synt_D PF01813.17 KND92379.1 - 0.00083 19.2 0.3 0.0012 18.7 0.2 1.5 1 1 0 1 1 1 1 ATP synthase subunit D ZapB PF06005.12 KND92379.1 - 0.0055 17.1 0.5 0.012 16.0 0.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB Metal_resist PF13801.6 KND92379.1 - 3.8 7.7 13.8 1.1 9.4 5.8 2.3 2 0 0 2 2 2 0 Heavy-metal resistance EIIBC-GUT_N PF03612.14 KND92380.1 - 0.23 11.2 0.2 1.1 9.0 0.4 1.8 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Zip PF02535.22 KND92381.1 - 5.8e-37 127.7 14.3 1.2e-27 97.0 5.0 3.1 3 0 0 3 3 3 3 ZIP Zinc transporter WD40 PF00400.32 KND92382.1 - 1.1e-32 111.5 29.9 1.9e-06 28.5 0.6 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KND92382.1 - 2.1e-12 46.7 0.6 4.3e-12 45.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KND92382.1 - 2e-08 34.4 0.7 0.4 11.0 0.0 5.9 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KND92382.1 - 7.6e-06 25.7 2.1 1.6e-05 24.6 2.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KND92382.1 - 0.00062 18.5 7.6 6 5.4 0.2 5.5 1 1 5 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KND92382.1 - 0.019 14.3 0.0 0.1 11.9 0.0 2.0 2 1 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 KND92382.1 - 0.022 14.3 1.6 0.13 11.8 1.2 2.4 1 1 1 2 2 2 0 PQQ-like domain zf_C2HC_14 PF18574.1 KND92382.1 - 0.039 13.7 0.1 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 C2HC Zing finger domain PQQ_3 PF13570.6 KND92382.1 - 0.049 14.1 0.1 14 6.3 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain E1_dh PF00676.20 KND92383.1 - 7.4e-112 373.2 0.7 1.5e-111 372.2 0.7 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component DNA_ligase_A_M PF01068.21 KND92383.1 - 1.7e-61 207.4 1.0 5.7e-49 166.5 0.3 2.6 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KND92383.1 - 2.9e-43 148.2 0.0 6e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KND92383.1 - 5.6e-28 97.4 0.0 2.5e-27 95.4 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KND92383.1 - 5.6e-06 26.8 0.2 1.3e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 RNA ligase DXP_synthase_N PF13292.6 KND92383.1 - 0.0084 15.3 0.1 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Synaptonemal_3 PF15191.6 KND92383.1 - 0.043 13.6 0.1 0.96 9.3 0.0 2.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 Presenilin PF01080.17 KND92383.1 - 0.49 9.1 2.7 0.88 8.3 2.7 1.4 1 0 0 1 1 1 0 Presenilin SPC25 PF06703.11 KND92384.1 - 2e-51 174.0 0.0 2.3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Peripla_BP_4 PF13407.6 KND92384.1 - 0.02 14.5 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain EMC3_TMCO1 PF01956.16 KND92385.1 - 7.1e-53 178.8 1.0 9.9e-53 178.3 1.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Alg6_Alg8 PF03155.15 KND92386.1 - 5.5e-128 428.0 30.5 1.7e-79 268.1 13.4 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family SpoIIE PF07228.12 KND92387.1 - 2.1e-10 40.9 0.2 1.2e-09 38.4 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KND92387.1 - 1.2e-06 28.3 0.4 2.7e-06 27.2 0.4 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KND92387.1 - 0.00092 18.9 0.0 0.079 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C RNA_pol_Rbc25 PF08292.12 KND92389.1 - 2.9e-33 114.8 1.7 4e-32 111.2 1.7 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KND92389.1 - 6e-14 52.2 0.0 8.5e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KND92390.1 - 9.8e-08 31.7 0.2 2.4e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KND92390.1 - 0.022 14.8 6.8 0.04 14.0 6.8 1.5 1 0 0 1 1 1 0 Zinc finger domain YPEB PF14620.6 KND92390.1 - 0.03 13.7 1.0 0.046 13.1 1.0 1.2 1 0 0 1 1 1 0 YpeB sporulation CENP-K PF11802.8 KND92390.1 - 0.049 13.2 1.4 0.078 12.5 1.4 1.2 1 0 0 1 1 1 0 Centromere-associated protein K zf-CCCH PF00642.24 KND92390.1 - 0.13 12.2 5.5 0.28 11.2 5.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HAUS6_N PF14661.6 KND92390.1 - 0.31 10.6 3.5 0.57 9.7 3.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PIEZO PF15917.5 KND92390.1 - 0.32 10.5 4.6 0.53 9.7 4.6 1.3 1 0 0 1 1 1 0 Piezo zf-CCCH_4 PF18044.1 KND92390.1 - 3.8 7.4 6.6 14 5.6 6.6 1.9 1 1 0 1 1 1 0 CCCH-type zinc finger SPT2 PF08243.11 KND92391.1 - 1.4e-09 38.5 24.5 2.4e-08 34.5 11.1 2.3 1 1 1 2 2 2 2 SPT2 chromatin protein PBP1_TM PF14812.6 KND92391.1 - 0.019 15.3 4.8 0.019 15.3 4.8 2.9 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 KND92392.1 - 4.3e-26 91.3 10.4 4.9e-26 91.1 10.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 KND92392.1 - 0.009 16.3 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain Methyltransf_23 PF13489.6 KND92394.1 - 2.9e-08 33.7 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND92394.1 - 2.6e-05 24.9 0.0 0.0001 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92394.1 - 8.5e-05 23.2 0.0 0.00023 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND92394.1 - 0.0099 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND92394.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ATP-synt_C PF00137.21 KND92395.1 - 1.3e-29 102.3 27.9 1e-20 73.8 12.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 KND92395.1 - 0.12 12.1 1.8 5.7 6.7 0.0 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Pep3_Vps18 PF05131.14 KND92396.1 - 2.6e-44 150.6 0.0 9.6e-44 148.8 0.0 2.1 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KND92396.1 - 3.8e-11 43.0 7.6 2.8e-07 30.5 0.1 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 KND92396.1 - 1.9e-06 28.1 2.2 0.00047 20.4 0.1 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.6 KND92396.1 - 0.00022 21.0 0.8 0.00051 19.8 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND92396.1 - 0.00076 19.1 0.1 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KND92396.1 - 0.0021 18.0 0.6 0.0021 18.0 0.6 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND92396.1 - 0.0047 17.2 0.7 0.011 16.0 0.7 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.9 KND92396.1 - 0.013 15.9 0.0 0.05 14.1 0.0 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 KND92396.1 - 0.053 13.5 0.8 0.13 12.4 0.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KND92396.1 - 0.1 12.9 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND92396.1 - 0.13 12.1 0.4 0.39 10.6 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KND92396.1 - 1 9.4 8.9 0.036 14.1 2.2 2.0 3 0 0 3 3 3 0 Zinc-finger DUF1599 PF07659.11 KND92396.1 - 1.2 9.7 3.0 0.92 10.0 0.1 2.3 3 0 0 3 3 2 0 Nucleotide modification associated domain 1 zf-RING_11 PF17123.5 KND92396.1 - 2.5 7.9 11.5 0.099 12.4 4.7 2.1 2 0 0 2 2 2 0 RING-like zinc finger Nup54_57_C PF18570.1 KND92396.1 - 8.7 6.0 6.0 2 8.1 0.0 2.7 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain Abhydrolase_6 PF12697.7 KND92397.1 - 1.8e-08 35.3 0.1 2.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 KND92397.1 - 7.6e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 KND92397.1 - 0.00011 22.0 0.1 0.00015 21.5 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 KND92397.1 - 0.00015 21.4 0.0 0.00066 19.2 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KND92397.1 - 0.0029 16.9 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KND92397.1 - 0.069 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_9 PF10081.9 KND92397.1 - 0.092 11.8 0.0 0.17 10.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta-hydrolase family Ser_hydrolase PF06821.13 KND92397.1 - 0.13 12.1 0.2 2.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Serine hydrolase Asp PF00026.23 KND92398.1 - 6.4e-68 229.5 1.5 7.9e-68 229.2 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND92398.1 - 5.3e-11 43.1 2.7 1e-09 38.9 2.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND92398.1 - 0.001 19.7 1.1 3.4 8.4 0.1 3.9 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 KND92398.1 - 0.0062 16.3 0.0 0.027 14.3 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Homeobox_KN PF05920.11 KND92399.1 - 5.8e-21 74.1 0.6 1.3e-20 72.9 0.6 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KND92399.1 - 1.7e-08 34.2 1.4 3.9e-08 33.0 1.4 1.6 1 0 0 1 1 1 1 Homeodomain HTH_32 PF13565.6 KND92399.1 - 0.98 10.1 3.8 2.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain ABC_tran PF00005.27 KND92400.1 - 6.1e-05 23.6 0.0 0.0001 22.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter GDP_Man_Dehyd PF16363.5 KND92401.1 - 6e-70 236.3 0.0 7e-70 236.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KND92401.1 - 3.7e-59 200.1 0.1 4.6e-59 199.8 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND92401.1 - 5.2e-22 78.2 0.0 7e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KND92401.1 - 1.7e-21 76.7 0.0 1.5e-20 73.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KND92401.1 - 1.2e-18 67.3 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KND92401.1 - 1.2e-17 63.9 0.1 8.3e-17 61.2 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KND92401.1 - 4.3e-08 33.3 0.0 8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KND92401.1 - 0.03 13.8 0.0 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_33 PF10017.9 KND92402.1 - 1.2e-79 267.7 0.0 1.7e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KND92402.1 - 1.2e-13 51.3 0.7 7e-13 48.8 0.7 2.0 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KND92402.1 - 6.5e-06 26.7 1.6 2.9e-05 24.6 0.3 2.6 2 0 0 2 2 2 1 DinB superfamily IF-2B PF01008.17 KND92403.1 - 4.8e-46 157.2 0.0 5.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family SpoU_sub_bind PF08032.12 KND92403.1 - 0.13 12.6 0.0 0.46 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Peptidase_C2 PF00648.21 KND92404.1 - 0.015 14.3 0.2 0.015 14.3 0.2 1.5 2 0 0 2 2 2 0 Calpain family cysteine protease DUF2102 PF09875.9 KND92404.1 - 0.16 11.7 5.1 0.32 10.8 5.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) GalP_UDP_transf PF01087.22 KND92405.1 - 6.3e-66 222.3 0.0 2e-64 217.4 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KND92405.1 - 4.5e-56 189.2 0.0 1.1e-55 187.9 0.0 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KND92405.1 - 0.012 16.3 0.0 0.037 14.8 0.0 1.9 2 0 0 2 2 2 0 HIT domain DcpS_C PF11969.8 KND92405.1 - 0.074 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Erg28 PF03694.13 KND92406.1 - 2.6e-45 153.3 0.1 3.2e-45 153.0 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 KND92407.1 - 3.6e-36 124.5 0.0 4.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND92407.1 - 6.9e-23 81.4 0.0 9.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND92407.1 - 3.5e-06 27.0 0.0 7.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND92407.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KND92407.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding tRNA-synt_His PF13393.6 KND92408.1 - 3.8e-37 128.2 0.0 5.6e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KND92408.1 - 9.3e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 KND92408.1 - 0.048 12.7 0.0 0.62 9.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Nucleoporin_N PF08801.11 KND92409.1 - 5.6e-96 321.9 0.1 8e-96 321.4 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KND92409.1 - 1.3e-52 179.4 0.5 1.8e-51 175.6 0.0 2.2 2 1 1 3 3 3 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF2781 PF10914.8 KND92411.1 - 1.6e-31 109.7 4.0 1.8e-31 109.5 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) AMP-binding PF00501.28 KND92412.1 - 3.2e-81 273.1 0.0 3.9e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND92412.1 - 8.3e-13 49.1 0.7 3.6e-12 47.1 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KND92413.1 - 2.9e-35 121.8 40.9 2.9e-35 121.8 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND92413.1 - 2.3e-15 56.4 8.4 2.3e-15 56.4 8.4 2.7 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KND92413.1 - 8e-09 34.5 1.3 1.3e-08 33.8 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PrpF PF04303.13 KND92414.1 - 3.7e-84 282.8 0.2 4.2e-84 282.6 0.2 1.0 1 0 0 1 1 1 1 PrpF protein GGACT PF06094.12 KND92416.1 - 1.1e-07 32.5 0.1 1.4e-07 32.1 0.1 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KND92416.1 - 6e-06 26.6 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Pkinase PF00069.25 KND92417.1 - 6.6e-67 225.7 0.0 1.3e-66 224.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92417.1 - 3e-48 164.4 0.0 5.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KND92417.1 - 1.9e-27 95.5 0.0 3.3e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KND92417.1 - 7.5e-15 55.1 0.1 1.4e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KND92417.1 - 7.6e-15 54.8 0.3 3e-14 52.8 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RA PF00788.23 KND92417.1 - 1.3e-13 51.4 0.1 2.4e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KND92417.1 - 7.6e-06 25.4 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KND92417.1 - 0.0042 15.9 0.3 0.0089 14.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 KND92417.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 KND92417.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 KND92417.1 - 0.28 11.5 1.5 0.4 11.0 0.3 1.9 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Relaxase PF03432.14 KND92417.1 - 0.44 10.1 1.8 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain PDT PF00800.18 KND92418.1 - 4.3e-59 199.4 0.0 5.4e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 KND92418.1 - 2.6e-06 27.1 0.0 2.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 ACT domain ACT_4 PF13291.6 KND92418.1 - 0.0085 16.7 0.0 6.8 7.4 0.1 2.4 2 0 0 2 2 2 2 ACT domain Dynamin_N PF00350.23 KND92419.1 - 4.9e-27 95.0 0.0 1.1e-26 93.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND92419.1 - 2.7e-10 39.9 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KND92419.1 - 0.00074 19.6 0.0 0.0026 17.9 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain COG5 PF10392.9 KND92419.1 - 0.028 14.6 1.6 0.097 12.8 0.3 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FeoB_N PF02421.18 KND92419.1 - 0.088 12.3 0.0 0.73 9.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AvrM_N PF18247.1 KND92419.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain 2OG-FeII_Oxy PF03171.20 KND92420.1 - 2.4e-19 69.7 0.0 4.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KND92420.1 - 1.8e-05 25.5 0.0 3.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Condensation PF00668.20 KND92421.1 - 6.4e-17 61.4 0.0 8.1e-16 57.7 0.0 2.2 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KND92421.1 - 1.5e-12 47.6 0.1 3.7e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1515 PF07439.11 KND92422.1 - 0.053 13.6 0.9 0.068 13.2 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Polysacc_deac_1 PF01522.21 KND92423.1 - 1.3e-31 109.1 0.0 1.4e-30 105.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KND92423.1 - 0.0003 21.2 12.9 0.00056 20.3 12.9 1.4 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 KND92423.1 - 0.23 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 TauD PF02668.16 KND92425.1 - 2.4e-61 207.9 0.9 2.9e-61 207.6 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KND92426.1 - 2.9e-10 39.6 54.9 5.7e-09 35.4 53.5 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KND92426.1 - 0.65 8.2 11.8 2.6 6.2 4.0 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BTB PF00651.31 KND92427.1 - 9e-09 35.5 0.1 3e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF1216 PF06746.11 KND92427.1 - 0.066 13.2 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) PrpR_N PF06506.11 KND92430.1 - 0.065 12.8 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Propionate catabolism activator ADH_zinc_N PF00107.26 KND92431.1 - 3e-25 88.7 0.3 3e-25 88.7 0.3 2.9 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND92431.1 - 3.5e-09 37.8 2.6 1.5e-08 35.8 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND92431.1 - 2e-08 34.1 0.0 1.1e-07 31.7 0.0 2.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KND92431.1 - 0.002 18.0 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Epimerase PF01370.21 KND92432.1 - 3.9e-46 157.5 0.0 4.9e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND92432.1 - 2.8e-45 155.2 0.0 4.5e-45 154.5 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KND92432.1 - 1.4e-15 57.1 0.0 9.9e-15 54.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KND92432.1 - 3.5e-14 52.6 0.0 2.5e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KND92432.1 - 1.9e-11 43.6 0.0 2.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 KND92432.1 - 6e-09 36.1 0.0 1.1e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KND92432.1 - 3.9e-08 33.0 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KND92432.1 - 4.1e-06 26.8 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KND92432.1 - 6.4e-06 25.5 0.0 8.9e-05 21.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KND92432.1 - 0.0018 17.9 0.1 0.0088 15.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 KND92432.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 KND92432.1 - 0.0063 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3533 PF12051.8 KND92433.1 - 4.7e-93 312.1 11.1 5.7e-93 311.8 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ank_2 PF12796.7 KND92435.1 - 1.6e-21 76.7 0.9 1.8e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND92435.1 - 1.3e-19 70.3 0.1 1.6e-07 31.7 0.1 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND92435.1 - 4.9e-18 63.3 0.0 2.2e-05 24.5 0.0 4.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KND92435.1 - 1.1e-17 63.9 1.7 2.1e-07 31.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KND92435.1 - 6.5e-16 58.0 0.9 0.00033 21.0 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat DUF2235 PF09994.9 KND92438.1 - 3.7e-101 338.3 0.1 3.7e-101 338.3 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) adh_short PF00106.25 KND92438.1 - 2.1e-13 50.2 0.0 9e-13 48.1 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND92438.1 - 5e-06 26.2 0.0 1.3e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND92438.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND92438.1 - 0.00026 20.5 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Com_YlbF PF06133.11 KND92438.1 - 6.4 7.4 9.3 4.8 7.8 6.1 2.3 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA F-box-like PF12937.7 KND92439.1 - 0.00019 21.3 0.2 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like APH PF01636.23 KND92440.1 - 1e-08 35.4 0.0 4.2e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KND92440.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase TRAM_LAG1_CLN8 PF03798.16 KND92441.1 - 1.5e-36 126.1 17.1 1.5e-36 126.1 17.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KND92441.1 - 1.3e-23 82.4 0.0 1.3e-23 82.4 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Apt1 PF10351.9 KND92441.1 - 0.55 9.0 5.4 0.91 8.3 5.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 KND92441.1 - 3.9 5.9 8.2 5.4 5.5 8.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 KND92441.1 - 3.9 7.4 10.9 7.6 6.5 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF508 PF04370.12 KND92441.1 - 6.3 6.5 8.3 10 5.8 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Herpes_DNAp_acc PF04929.12 KND92441.1 - 7.6 5.4 7.0 12 4.7 7.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3494 PF11999.8 KND92442.1 - 2.3e-59 200.5 17.8 3.4e-59 200.0 17.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) ABC_tran PF00005.27 KND92443.1 - 1e-32 113.5 0.0 2.4e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KND92443.1 - 4.9e-26 92.0 1.9 4.9e-26 92.0 1.9 2.1 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 KND92443.1 - 3.2e-05 23.5 0.0 0.00013 21.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KND92443.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 KND92443.1 - 0.014 15.1 0.5 0.074 12.8 0.5 2.1 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 KND92443.1 - 0.026 14.7 0.2 0.85 9.9 0.2 3.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KND92443.1 - 0.079 12.7 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain muHD PF10291.9 KND92444.1 - 2.3e-66 224.0 0.0 4.9e-66 222.9 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KND92444.1 - 1.2e-07 32.0 0.2 3.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 KND92444.1 - 0.027 14.0 7.4 0.062 12.8 7.4 1.5 1 1 0 1 1 1 0 Vps5 C terminal like Hc1 PF07432.13 KND92444.1 - 0.061 13.7 2.0 0.084 13.2 0.4 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 Laminin_II PF06009.12 KND92444.1 - 0.081 12.9 2.8 0.25 11.4 2.8 1.8 1 0 0 1 1 1 0 Laminin Domain II Cys_Met_Meta_PP PF01053.20 KND92444.1 - 0.1 11.1 0.0 0.32 9.5 0.0 1.7 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Muted PF14942.6 KND92444.1 - 0.28 11.5 10.1 0.17 12.2 7.2 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 KND92444.1 - 3.7 7.0 8.8 6.3 6.3 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 KND92445.1 - 4.1e-30 105.0 0.0 5.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND92445.1 - 2.6e-05 24.3 0.1 0.00021 21.3 0.1 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND92445.1 - 6.5e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 KND92447.1 - 1.4e-08 34.9 8.8 3.7e-08 33.6 8.8 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KND92447.1 - 1.3e-05 25.2 8.4 4e-05 23.7 8.4 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 KND92447.1 - 0.00029 21.1 7.3 0.00079 19.7 7.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KND92447.1 - 0.00062 19.6 9.6 0.0014 18.5 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KND92447.1 - 0.0012 18.9 2.6 0.0012 18.9 2.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 KND92447.1 - 0.0028 17.7 7.5 0.0061 16.7 7.5 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 KND92447.1 - 0.0049 16.7 2.6 0.0049 16.7 2.6 1.9 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 KND92447.1 - 0.0089 15.6 5.2 0.018 14.6 5.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KND92447.1 - 0.023 14.5 8.2 0.054 13.3 8.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND92447.1 - 0.026 14.4 5.8 0.053 13.4 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 KND92447.1 - 0.062 13.6 8.0 0.13 12.6 8.0 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 KND92447.1 - 0.7 9.8 6.2 1.6 8.7 6.2 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 KND92447.1 - 0.75 9.7 6.6 2.4 8.1 6.6 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND92447.1 - 1.7 8.6 8.7 3.6 7.6 8.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 KND92447.1 - 2.5 8.1 6.9 4.9 7.1 6.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 KND92447.1 - 8.9 6.2 8.1 3e+02 1.3 8.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Hormone_3 PF00159.18 KND92448.1 - 0.17 12.0 27.6 25 5.0 0.0 9.6 11 0 0 11 11 11 0 Pancreatic hormone peptide Palm_thioest PF02089.15 KND92449.1 - 1.1e-79 267.8 0.0 1.3e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 KND92449.1 - 0.00015 21.4 0.0 0.0012 18.5 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.11 KND92449.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.21 KND92450.1 - 4.5e-68 229.0 0.8 4.5e-68 229.0 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family F_actin_bind PF08919.10 KND92451.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 F-actin binding zf-H2C2_2 PF13465.6 KND92451.1 - 4.4 7.9 8.4 17 6.1 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double domain AMP-binding PF00501.28 KND92453.1 - 0 3599.2 0.0 3.2e-78 263.2 0.0 16.4 16 0 0 16 16 16 16 AMP-binding enzyme Condensation PF00668.20 KND92453.1 - 0 2367.5 0.0 8.9e-49 166.4 0.0 16.3 16 0 0 16 16 16 16 Condensation domain PP-binding PF00550.25 KND92453.1 - 4.4e-178 577.9 64.7 4e-12 46.3 0.2 17.0 16 0 0 16 16 16 16 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KND92453.1 - 2.6e-08 34.7 0.0 88 4.2 0.0 10.7 11 0 0 11 11 11 0 AMP-binding enzyme C-terminal domain Mig-14 PF07395.11 KND92453.1 - 0.0033 16.8 0.0 78 2.5 0.0 5.4 5 0 0 5 5 5 0 Mig-14 HbrB PF08539.11 KND92454.1 - 1.1e-52 178.4 0.2 2.7e-52 177.2 0.0 1.8 2 0 0 2 2 2 1 HbrB-like Vps39_1 PF10366.9 KND92455.1 - 4.4e-35 120.2 0.0 1.5e-33 115.3 0.0 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KND92455.1 - 3.9e-26 91.6 0.0 1.6e-25 89.6 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KND92455.1 - 1.6e-12 47.6 0.0 4.6e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KND92455.1 - 0.00091 19.1 2.3 0.63 9.9 0.1 3.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 KND92455.1 - 0.007 16.1 1.2 8.4 6.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND92455.1 - 0.023 14.9 0.3 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Cnd1_N PF12922.7 KND92455.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term TPR_19 PF14559.6 KND92455.1 - 0.11 13.0 0.1 1.8 9.2 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND92455.1 - 0.12 12.6 0.1 1.2e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat KH_1 PF00013.29 KND92456.1 - 1.3e-46 156.3 13.4 5e-16 58.3 0.8 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KND92456.1 - 5.7e-12 45.3 2.5 0.018 14.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KND92456.1 - 9.4e-09 35.0 5.8 0.089 12.7 0.2 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 KND92456.1 - 0.00084 19.3 0.0 0.69 10.0 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 KND92456.1 - 0.0014 18.6 4.9 0.99 9.5 0.1 3.5 4 0 0 4 4 4 2 NusA-like KH domain 6PF2K PF01591.18 KND92460.1 - 7.5e-78 260.9 0.0 1e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KND92460.1 - 3.5e-35 121.5 0.0 6.5e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KND92460.1 - 4.1e-06 27.0 0.0 8.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KND92460.1 - 0.0015 18.4 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 KND92460.1 - 0.002 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 LIM_bind PF01803.16 KND92461.1 - 6.1e-73 245.3 0.0 6.1e-73 245.3 0.0 4.9 2 1 1 3 3 3 1 LIM-domain binding protein Asp PF00026.23 KND92463.1 - 5.9e-34 117.9 0.0 8.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 KND92463.1 - 0.00017 22.2 0.0 1.4 9.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 KND92463.1 - 0.00064 19.5 0.0 0.031 14.0 0.0 2.7 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 KND92463.1 - 0.098 13.2 0.0 11 6.7 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RGS12_us2 PF16611.5 KND92464.1 - 0.032 14.6 0.6 0.068 13.6 0.6 1.5 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco EMC1_C PF07774.13 KND92464.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Peptidase_U4 PF03419.13 KND92464.1 - 0.12 11.6 2.2 0.17 11.1 2.2 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA GEN1_C PF18380.1 KND92466.1 - 1.4e-27 96.6 0.2 6.6e-27 94.5 0.2 2.2 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KND92466.1 - 1.5e-25 89.3 0.0 3.1e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KND92466.1 - 2e-07 31.4 0.0 5.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KND92466.1 - 0.067 12.7 0.1 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 XPG domain containing VHS PF00790.19 KND92467.1 - 2e-05 24.5 0.0 7.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 VHS domain CFIA_Pcf11 PF11526.8 KND92467.1 - 2.5e-05 24.7 4.0 8.4e-05 23.0 4.0 1.9 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KND92467.1 - 6.9e-05 23.6 0.0 0.00015 22.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.6 KND92467.1 - 0.12 13.3 1.5 20 6.4 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KND92467.1 - 1.4 9.0 4.7 4.9 7.2 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RRN7 PF11781.8 KND92467.1 - 1.5 8.5 3.5 1 9.1 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf_UBZ PF18439.1 KND92467.1 - 8.4 6.1 8.5 4.2 7.0 2.7 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Actin PF00022.19 KND92468.1 - 2.1e-20 72.7 0.0 8.5e-19 67.4 0.0 2.8 2 1 0 2 2 2 1 Actin Dscam_C PF12355.8 KND92468.1 - 9.2 7.2 8.5 1.2 10.1 3.7 1.9 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal FOXP-CC PF16159.5 KND92469.1 - 3.8e-06 27.4 1.4 0.0058 17.2 1.0 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KND92469.1 - 0.16 12.9 1.2 2.3 9.3 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.25 KND92470.1 - 1.2e-23 83.6 0.0 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND92470.1 - 1.3e-20 74.0 0.1 1.6e-20 73.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND92470.1 - 6.3e-05 23.0 0.1 9.1e-05 22.4 0.1 1.3 1 1 0 1 1 1 1 KR domain Oxidored_FMN PF00724.20 KND92471.1 - 3.5e-45 154.8 0.0 4.4e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KND92471.1 - 7.4e-05 22.0 0.1 7.4e-05 22.0 0.1 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KND92471.1 - 0.098 12.1 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein CFEM PF05730.11 KND92472.1 - 0.026 14.6 4.3 0.055 13.6 4.3 1.5 1 0 0 1 1 1 0 CFEM domain UPF0261 PF06792.11 KND92473.1 - 2.8e-11 43.0 0.0 3e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Epimerase PF01370.21 KND92473.1 - 0.053 13.0 0.0 0.054 13.0 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cellulase PF00150.18 KND92474.1 - 4.5e-42 144.4 0.0 6.2e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S2 PF00318.20 KND92474.1 - 0.032 13.5 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 Ribul_P_3_epim PF00834.19 KND92474.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family F-box-like PF12937.7 KND92475.1 - 1.4e-07 31.3 0.2 2.6e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND92475.1 - 2.7e-06 27.1 0.1 5e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain SWIRM PF04433.17 KND92476.1 - 4.7e-14 52.5 0.0 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain PEP_hydrolase PF09370.10 KND92477.1 - 2e-136 453.4 0.2 2.3e-136 453.3 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 KND92477.1 - 0.00059 19.3 0.1 0.00059 19.3 0.1 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase UPF0261 PF06792.11 KND92478.1 - 2.6e-133 444.9 3.4 2.9e-133 444.8 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Fungal_trans PF04082.18 KND92480.1 - 3.9e-16 58.9 0.3 5.4e-15 55.1 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92480.1 - 0.0023 18.0 4.3 0.0072 16.4 4.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnl2_NKP2 PF09447.10 KND92480.1 - 0.063 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Cnl2/NKP2 family protein zf-C2H2_jaz PF12171.8 KND92481.1 - 3.1e-05 24.1 0.1 6.2e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND92481.1 - 0.0022 18.3 0.6 0.0039 17.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KND92481.1 - 0.063 13.6 0.2 0.097 13.0 0.2 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KND92481.1 - 0.08 13.8 0.4 0.16 12.9 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KND92481.1 - 0.13 12.7 0.9 0.26 11.8 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2057 PF09829.9 KND92481.1 - 0.87 9.7 4.4 8.7 6.5 3.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF1691 PF07950.11 KND92482.1 - 4.2e-37 127.1 6.7 2.3e-31 108.7 2.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) ADPRTs_Tse2 PF18648.1 KND92483.1 - 8.6e-06 25.9 0.0 1.6e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Tse2 ADP-ribosyltransferase toxins Glyco_transf_34 PF05637.12 KND92484.1 - 3.8e-69 233.0 0.0 4.7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 KND92484.1 - 0.0054 16.3 0.0 0.082 12.5 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.19 KND92485.1 - 1.6e-18 66.6 0.0 2.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KND92485.1 - 4.5e-05 22.6 0.0 7.8e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Proteasome PF00227.26 KND92488.1 - 2.3e-55 187.0 0.1 8.6e-33 113.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KND92488.1 - 1.1e-10 40.9 0.3 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 KND92489.1 - 6.7e-10 38.9 3.9 8.1e-09 35.5 1.2 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 KND92489.1 - 0.13 12.7 4.4 0.31 11.4 1.3 2.2 2 0 0 2 2 2 0 Ring finger domain FA_desaturase PF00487.24 KND92489.1 - 0.18 11.6 1.2 0.49 10.2 0.0 1.9 1 1 1 2 2 2 0 Fatty acid desaturase PHD PF00628.29 KND92489.1 - 0.35 10.8 6.5 0.068 13.1 2.6 1.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KND92489.1 - 0.94 9.6 5.5 6.9 6.8 6.0 2.0 1 1 1 2 2 2 0 PHD-finger DUF202 PF02656.15 KND92489.1 - 2.9 8.4 8.1 97 3.5 0.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) GRAB PF10375.9 KND92490.1 - 6.7e-07 28.9 0.3 1.3e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain FPP PF05911.11 KND92490.1 - 0.0003 19.2 26.9 0.0003 19.2 26.9 2.3 1 1 1 2 2 1 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 KND92490.1 - 0.00041 19.3 29.1 0.00041 19.3 29.1 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein ADIP PF11559.8 KND92490.1 - 0.0045 17.1 10.1 0.0045 17.1 10.1 4.4 1 1 3 4 4 4 1 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 KND92490.1 - 0.0046 17.0 11.1 0.0046 17.0 11.1 5.2 1 1 5 6 6 5 3 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KND92490.1 - 0.0068 16.7 3.5 0.0068 16.7 3.5 4.7 2 1 1 4 4 4 1 Tup N-terminal Filament PF00038.21 KND92490.1 - 0.031 13.9 53.3 0.09 12.3 28.9 2.9 1 1 1 2 2 2 0 Intermediate filament protein DUF641 PF04859.12 KND92490.1 - 0.051 13.9 41.0 0.44 10.9 5.7 4.1 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 KND92490.1 - 0.16 11.4 57.9 1.4 8.3 5.3 3.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 KND92490.1 - 0.39 11.2 17.6 3.2 8.3 0.8 4.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 KND92490.1 - 0.81 9.0 54.6 0.098 12.0 13.3 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 KND92490.1 - 1.2 8.1 47.7 0.071 12.2 18.8 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KND92490.1 - 1.8 8.6 62.4 1.2 9.1 11.4 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KND92490.1 - 2.6 8.1 30.7 0.35 10.9 4.3 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 KND92490.1 - 5.7 7.0 36.9 0.22 11.5 5.3 4.3 1 1 3 4 4 4 0 Laminin Domain II DUF3584 PF12128.8 KND92490.1 - 5.9 4.3 58.9 0.21 9.1 40.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rootletin PF15035.6 KND92490.1 - 8.8 6.3 56.1 0.27 11.2 20.3 3.6 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion FAD_binding_3 PF01494.19 KND92491.1 - 2.2e-14 53.5 1.1 5.7e-13 48.8 1.1 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KND92491.1 - 0.0066 16.7 0.2 0.023 14.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND92491.1 - 0.051 13.1 0.1 3 7.3 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND92491.1 - 0.074 12.3 0.0 0.93 8.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND92491.1 - 0.12 12.3 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding RRM_1 PF00076.22 KND92492.1 - 2.9e-14 52.6 0.0 6.7e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND92492.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KND92492.1 - 0.085 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cu_bind_like PF02298.17 KND92494.1 - 0.00049 20.0 0.1 0.0017 18.3 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain SMN PF06003.12 KND92495.1 - 8.9e-06 25.1 5.3 0.00025 20.4 0.3 2.3 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) APH PF01636.23 KND92496.1 - 0.00055 19.9 0.2 0.00069 19.6 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND92496.1 - 0.0033 17.0 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KND92496.1 - 0.0039 16.6 0.0 0.0042 16.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.18 KND92497.1 - 8e-11 41.9 13.5 8e-11 41.9 13.5 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KND92497.1 - 0.023 14.8 10.3 0.45 10.6 8.4 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KND92497.1 - 0.041 14.2 10.9 0.041 14.2 10.9 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Macro_2 PF14519.6 KND92498.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Macro-like domain Macro PF01661.21 KND92498.1 - 0.19 11.8 0.0 1.8 8.6 0.0 2.1 1 1 0 1 1 1 0 Macro domain Glyco_hydro_16 PF00722.21 KND92500.1 - 3.3e-09 36.4 0.3 4.3e-09 36.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 KND92500.1 - 1.3e-06 27.1 0.0 0.005 15.3 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) HsbA PF12296.8 KND92501.1 - 1.2e-26 93.5 10.1 2.4e-26 92.5 10.1 1.5 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Lipoprotein_6 PF01441.19 KND92501.1 - 0.064 13.3 1.4 0.13 12.3 1.4 1.4 1 1 0 1 1 1 0 Lipoprotein FAD_binding_3 PF01494.19 KND92502.1 - 1.5e-17 63.9 0.0 2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND92502.1 - 9.1e-08 31.7 0.1 0.008 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND92502.1 - 0.0024 18.4 0.1 0.013 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND92502.1 - 0.0031 17.2 0.2 0.013 15.1 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KND92502.1 - 0.027 13.3 0.1 1 8.1 0.0 2.4 2 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KND92502.1 - 0.032 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND92502.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NACHT_sigma PF17106.5 KND92503.1 - 2.3e-16 59.7 16.9 3.4e-16 59.1 16.9 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Glyco_hydro_88 PF07470.13 KND92504.1 - 2.5e-27 95.9 0.0 3.6e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Transket_pyr PF02779.24 KND92505.1 - 4.3e-44 150.3 0.0 1.6e-43 148.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KND92505.1 - 6.6e-37 126.2 0.0 1.6e-36 124.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DSHCT PF08148.12 KND92506.1 - 9.5e-51 171.7 0.5 2.2e-50 170.5 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KND92506.1 - 4.1e-39 133.5 0.0 3.9e-38 130.3 0.0 2.4 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KND92506.1 - 1e-31 110.9 0.1 1.9e-31 110.0 0.1 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KND92506.1 - 4.1e-18 65.7 0.0 1.8e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND92506.1 - 8.2e-07 29.4 0.0 3.2e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND92506.1 - 7.8e-05 22.7 0.0 0.0003 20.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cut8 PF08559.10 KND92506.1 - 0.025 14.2 0.1 0.089 12.4 0.1 1.9 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein SPX PF03105.19 KND92509.1 - 2.2e-39 136.5 5.3 5.3e-28 99.0 0.0 2.8 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 KND92509.1 - 6.3e-34 117.8 35.7 8.8e-34 117.3 35.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KND92509.1 - 4.8e-26 91.7 30.6 4.8e-26 91.7 30.6 2.2 2 1 1 3 3 3 2 Citrate transporter RANK_CRD_2 PF18278.1 KND92509.1 - 0.15 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Nairovirus_M PF07948.11 KND92509.1 - 0.15 10.2 0.1 0.26 9.4 0.1 1.3 1 0 0 1 1 1 0 Nairovirus M polyprotein-like ABC_membrane PF00664.23 KND92510.1 - 2.3e-83 280.0 22.2 3e-46 158.3 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND92510.1 - 1.1e-62 210.5 0.0 3.5e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND92510.1 - 4e-15 55.8 0.1 8.4e-05 22.1 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND92510.1 - 1.6e-06 27.8 1.6 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KND92510.1 - 9.5e-06 25.0 0.0 0.012 14.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 KND92510.1 - 5.7e-05 23.6 0.0 0.13 12.7 0.0 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KND92510.1 - 0.00014 21.8 0.0 0.55 10.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KND92510.1 - 0.00014 21.5 0.2 2.3 7.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KND92510.1 - 0.00016 22.1 3.1 0.38 11.1 0.3 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND92510.1 - 0.00019 21.7 0.5 3.4 7.9 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.6 KND92510.1 - 0.00042 20.1 5.5 0.14 11.9 0.2 3.9 3 1 0 3 3 3 1 AAA domain APS_kinase PF01583.20 KND92510.1 - 0.00097 19.1 0.2 0.14 12.0 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_33 PF13671.6 KND92510.1 - 0.0014 18.8 0.3 0.53 10.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 KND92510.1 - 0.0029 18.1 0.2 1.1 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KND92510.1 - 0.0038 17.4 0.2 5.2 7.4 0.2 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KND92510.1 - 0.0047 15.8 0.2 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KND92510.1 - 0.0055 16.6 4.5 5.6 6.7 0.0 4.0 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 KND92510.1 - 0.023 14.7 0.2 9.4 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 KND92510.1 - 0.025 15.0 0.2 10 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 KND92510.1 - 0.057 13.9 0.8 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KND92510.1 - 0.083 11.9 0.1 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Mg_chelatase PF01078.21 KND92510.1 - 0.097 12.0 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KND92510.1 - 0.098 12.2 0.5 5.4 6.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KND92510.1 - 0.13 12.3 2.0 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KND92510.1 - 0.16 11.7 0.0 24 4.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.28 KND92513.1 - 1.4e-95 320.4 0.0 1.8e-95 320.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND92513.1 - 2.8e-14 53.8 0.0 1e-13 52.0 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KND92513.1 - 0.044 14.1 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 KND92514.1 - 3.9e-24 85.4 0.3 8.1e-23 81.1 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND92514.1 - 6.7e-15 55.4 2.7 7.9e-13 48.8 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND92514.1 - 7.3e-06 25.3 0.1 1.4e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KND92514.1 - 5.5e-05 22.6 1.9 0.00017 20.9 0.6 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND92514.1 - 0.00021 20.5 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KND92514.1 - 0.0014 18.3 0.4 0.1 12.1 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND92514.1 - 0.0018 17.6 1.7 0.027 13.7 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KND92514.1 - 0.025 13.3 1.6 0.28 9.8 0.3 2.2 1 1 1 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 KND92514.1 - 0.059 13.8 0.3 0.16 12.5 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 KND92514.1 - 0.065 12.5 0.0 0.065 12.5 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KND92514.1 - 0.12 12.3 0.9 37 4.3 0.1 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KND92514.1 - 0.82 8.4 3.3 0.32 9.8 0.3 1.8 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.16 KND92515.1 - 5.9e-22 78.1 50.1 2.4e-18 66.2 50.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KND92515.1 - 3.6e-06 25.7 24.0 5.6e-06 25.1 24.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND92516.1 - 3.1e-88 296.6 23.5 3.8e-88 296.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND92516.1 - 7.4e-17 61.3 22.9 7.4e-17 61.3 22.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 KND92518.1 - 0.0052 17.5 17.2 0.11 13.4 1.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KND92518.1 - 0.044 14.2 19.9 0.26 11.8 1.9 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KND92518.1 - 0.059 13.7 8.2 2.1 8.8 2.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND92518.1 - 0.092 13.2 3.4 0.63 10.5 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_3 PF13878.6 KND92518.1 - 0.35 10.7 3.6 0.61 10.0 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO APH PF01636.23 KND92519.1 - 1.1e-07 32.0 0.1 1.8e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Xan_ur_permease PF00860.20 KND92521.1 - 9.8e-25 87.0 37.6 1.4e-23 83.3 34.3 2.7 2 1 0 2 2 2 1 Permease family Alpha-amylase PF00128.24 KND92524.1 - 1.7e-109 366.4 0.0 2.6e-109 365.9 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KND92524.1 - 0.017 15.2 0.0 0.091 12.9 0.0 2.1 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KND92524.1 - 0.047 12.8 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain E1_4HB PF16191.5 KND92524.1 - 0.14 12.4 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle LRR_4 PF12799.7 KND92525.1 - 3 8.4 14.9 4.6 7.8 2.1 4.6 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) VEFS-Box PF09733.9 KND92526.1 - 8.2e-06 25.7 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein DUF382 PF04037.13 KND92527.1 - 5.7e-59 197.8 0.3 5.7e-59 197.8 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 KND92527.1 - 3.1e-17 62.2 2.1 7.9e-17 60.9 2.1 1.7 1 0 0 1 1 1 1 PSP TPT PF03151.16 KND92528.1 - 2.7e-58 197.6 11.3 3.2e-58 197.4 11.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KND92528.1 - 1.3e-10 41.6 28.7 1.2e-05 25.5 12.0 3.2 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KND92528.1 - 3.5e-06 26.5 13.4 1.5e-05 24.3 13.4 1.8 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.19 KND92528.1 - 0.049 12.3 0.1 0.08 11.6 0.1 1.5 1 0 0 1 1 1 0 Photosystem II protein SLATT_5 PF18160.1 KND92528.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 PUNUT PF16913.5 KND92528.1 - 0.43 9.8 12.1 0.8 8.9 12.0 1.4 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Multi_Drug_Res PF00893.19 KND92528.1 - 1.5 9.6 8.5 0.56 10.9 1.7 2.9 3 0 0 3 3 3 0 Small Multidrug Resistance protein Mus7 PF09462.10 KND92529.1 - 3.9e-133 445.5 1.2 4.1e-133 445.4 0.4 1.4 2 0 0 2 2 2 1 Mus7/MMS22 family ORC5_C PF14630.6 KND92529.1 - 7.5e-82 275.0 0.0 2.3e-81 273.5 0.0 1.9 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Zn_clus PF00172.18 KND92531.1 - 8e-07 29.1 6.2 1.8e-06 28.0 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_AsnC-type PF13404.6 KND92531.1 - 0.075 12.9 0.4 0.73 9.7 0.0 2.6 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MFS_1 PF07690.16 KND92532.1 - 3.5e-50 170.9 63.6 1.3e-49 169.1 39.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND92532.1 - 9e-19 67.7 5.1 9e-19 67.7 5.1 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 KND92532.1 - 3.8e-10 39.6 4.4 3.8e-10 39.6 4.4 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 KND92532.1 - 0.87 10.0 3.1 4.7 7.7 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Arb2 PF09757.9 KND92533.1 - 4.6e-102 340.6 0.3 6.2e-102 340.1 0.3 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KND92533.1 - 1.8e-80 270.7 0.0 3.1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KND92534.1 - 1.7e-95 319.1 0.3 2.3e-95 318.6 0.3 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KND92534.1 - 1.8e-80 270.7 0.0 3.1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Nuc_sug_transp PF04142.15 KND92536.1 - 8.3e-97 324.1 8.2 1.3e-96 323.5 8.2 1.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KND92536.1 - 1.1e-07 32.1 26.5 1.6e-05 25.1 3.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KND92536.1 - 2.4e-07 30.2 11.9 1.7e-06 27.5 11.9 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KND92536.1 - 0.0048 16.3 13.5 0.15 11.3 0.8 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family TMEM234 PF10639.9 KND92536.1 - 0.26 11.3 9.8 1.3 9.1 2.4 2.7 3 0 0 3 3 3 0 Putative transmembrane family 234 DMT_6 PF04342.12 KND92536.1 - 3.1 8.1 9.9 8.1 6.7 1.1 3.0 2 1 1 3 3 3 0 Putative member of DMT superfamily (DUF486) Ank_2 PF12796.7 KND92537.1 - 6.1e-26 90.8 1.2 1.5e-09 38.3 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND92537.1 - 1.4e-21 76.5 0.0 3e-07 30.8 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KND92537.1 - 7.2e-21 73.7 1.9 0.00037 20.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KND92537.1 - 2.9e-20 72.1 1.1 1.4e-05 25.3 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND92537.1 - 6.6e-20 69.1 0.1 0.019 15.5 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Lactamase_B_5 PF14597.6 KND92538.1 - 0.0073 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B PF00753.27 KND92538.1 - 0.048 13.7 0.6 0.15 12.1 0.6 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-CRD PF17979.1 KND92538.1 - 0.14 12.3 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions DAO PF01266.24 KND92541.1 - 1.4e-32 113.7 0.2 1.7e-32 113.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND92541.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND92541.1 - 0.028 14.6 0.1 0.072 13.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Isochorismatase PF00857.20 KND92542.1 - 5e-14 52.8 0.0 9.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family NLPC_P60 PF00877.19 KND92543.1 - 1.2e-17 63.9 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 KND92543.1 - 5.6e-05 23.1 0.2 0.0001 22.2 0.1 1.5 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase DUF1175 PF06672.11 KND92543.1 - 0.053 13.2 0.2 2.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) MFS_1 PF07690.16 KND92544.1 - 3.1e-30 105.3 22.7 3.1e-30 105.3 22.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SKG6 PF08693.10 KND92546.1 - 0.00049 19.5 2.3 0.00049 19.5 2.3 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain NCU-G1 PF15065.6 KND92546.1 - 0.00096 18.2 0.5 0.0019 17.3 0.5 1.5 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Mid2 PF04478.12 KND92546.1 - 0.01 15.7 0.4 0.027 14.3 0.4 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor OMP_b-brl_3 PF14905.6 KND92546.1 - 0.028 13.4 0.6 0.049 12.6 0.6 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family Glyco_hydro_1 PF00232.18 KND92547.1 - 2.6e-74 250.3 0.9 6.1e-72 242.5 0.9 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 NACHT_N PF17100.5 KND92548.1 - 6.5e-24 85.0 0.0 1.1e-12 48.3 0.0 2.8 2 1 0 2 2 2 2 N-terminal domain of NWD NACHT-NTPase ketoacyl-synt PF00109.26 KND92549.1 - 2.2e-77 260.1 0.0 9.3e-77 258.0 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KND92549.1 - 1.1e-59 202.1 0.0 1.8e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KND92549.1 - 1.6e-55 187.8 4.1 3.5e-55 186.7 1.3 2.8 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 KND92549.1 - 1.8e-50 172.3 0.2 4.3e-50 171.0 0.2 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND92549.1 - 2.5e-39 133.9 0.1 5.9e-39 132.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KND92549.1 - 7.6e-20 71.5 0.0 2.1e-19 70.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KND92549.1 - 8.3e-18 64.6 0.1 4.5e-17 62.2 0.1 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KND92549.1 - 2.8e-14 53.0 0.9 5.7e-12 45.5 0.1 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 KND92549.1 - 5.4e-12 45.9 0.0 1.1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92549.1 - 1.3e-10 41.9 0.0 1.6e-09 38.3 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KND92549.1 - 1.6e-08 35.6 0.0 6.8e-07 30.4 0.0 3.3 3 1 1 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 KND92549.1 - 3.8e-08 33.9 0.0 1.3e-07 32.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND92549.1 - 1.5e-07 31.3 0.0 6.3e-07 29.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KND92549.1 - 1.5e-06 28.0 0.6 1.1e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KND92549.1 - 3.7e-06 26.5 0.0 8.7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 KND92549.1 - 1.3e-05 25.4 0.1 4.4e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 KND92549.1 - 3.1e-05 23.8 0.1 6.5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 KND92549.1 - 5.2e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 KND92549.1 - 0.00035 20.1 0.1 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SAT PF16073.5 KND92549.1 - 0.0019 18.0 0.3 0.0068 16.2 0.3 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis 3Beta_HSD PF01073.19 KND92549.1 - 0.014 14.4 0.0 0.046 12.7 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PALP PF00291.25 KND92549.1 - 0.041 13.3 0.2 0.17 11.2 0.2 2.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ACP_syn_III PF08545.10 KND92549.1 - 0.045 13.6 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ThiF PF00899.21 KND92549.1 - 0.083 12.2 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 ThiF family ACP_syn_III_C PF08541.10 KND92549.1 - 0.1 12.8 0.6 0.93 9.7 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CoA_trans PF01144.23 KND92549.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase MFS_1 PF07690.16 KND92552.1 - 9.5e-37 126.7 47.2 2.5e-36 125.3 45.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND92552.1 - 5.4e-11 41.6 17.4 5.4e-11 41.6 17.4 1.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KND92552.1 - 3.7e-07 29.4 33.3 0.00064 18.7 31.5 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter RNA_pol_Rpb1_5 PF04998.17 KND92554.1 - 8.7e-22 77.8 0.0 1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 DSBA PF01323.20 KND92555.1 - 3.4e-20 72.7 0.0 4e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Histone PF00125.24 KND92556.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KND92556.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KND92556.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KND92556.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KND92556.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KND92556.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KND92556.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KND92557.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KND92557.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KND92557.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KND92557.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KND92557.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KND92557.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KND92557.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KND92557.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KND92557.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region DEAD_2 PF06733.15 KND92558.1 - 5e-51 172.8 0.3 1.2e-50 171.5 0.0 1.9 2 1 0 2 2 2 1 DEAD_2 HBB PF06777.11 KND92558.1 - 7.6e-48 162.7 2.0 4.1e-44 150.5 0.4 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KND92558.1 - 1.5e-42 145.7 0.0 4.3e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KND92558.1 - 8.6e-05 22.6 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KND92558.1 - 0.0034 16.2 0.0 0.06 12.0 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KND92558.1 - 0.0083 15.9 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C PF13361.6 KND92558.1 - 0.023 14.1 0.5 0.04 13.3 0.5 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain KIF1B PF12423.8 KND92558.1 - 0.91 10.0 3.3 1.1 9.7 0.9 2.3 2 0 0 2 2 2 0 Kinesin protein 1B zf-C2H2 PF00096.26 KND92559.1 - 7.5e-12 45.0 22.9 1.7e-05 25.0 1.4 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND92559.1 - 4e-09 36.5 17.9 0.0021 18.8 0.4 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND92559.1 - 0.0032 17.8 21.6 0.0075 16.7 2.5 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KND92559.1 - 0.1 12.7 3.3 2.5 8.2 0.3 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 KND92559.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 KND92559.1 - 0.15 12.5 5.0 24 5.5 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KND92559.1 - 0.19 12.0 8.8 0.58 10.5 7.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-BED PF02892.15 KND92559.1 - 0.37 10.8 8.6 0.97 9.5 4.4 2.9 2 1 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 KND92559.1 - 0.96 9.8 9.3 30 5.0 0.0 3.7 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 KND92559.1 - 1 9.4 4.7 0.59 10.1 1.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PRP3 PF08572.10 KND92560.1 - 5.1e-54 183.4 10.4 1.9e-52 178.2 10.4 2.5 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KND92560.1 - 6.5e-47 159.3 0.5 6.5e-47 159.3 0.5 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) DUF2262 PF10020.9 KND92560.1 - 0.44 10.9 4.2 0.16 12.4 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) RNA_pol_Rpb1_2 PF00623.20 KND92561.1 - 1.4e-68 230.3 0.6 2.7e-68 229.4 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 KND92561.1 - 3.6e-63 213.5 0.1 6.4e-63 212.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KND92561.1 - 4.4e-24 85.2 0.0 2e-23 83.1 0.0 2.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KND92561.1 - 1.5e-21 77.1 6.9 6.5e-17 61.8 1.8 4.9 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KND92561.1 - 3.2e-17 62.4 0.0 1.4e-16 60.3 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FF PF01846.19 KND92563.1 - 8.6e-12 45.0 10.3 1.8e-08 34.4 0.4 2.7 2 0 0 2 2 2 2 FF domain WW PF00397.26 KND92563.1 - 2e-09 37.4 2.9 5.6e-09 35.9 2.9 1.9 1 0 0 1 1 1 1 WW domain TTSSLRR PF12468.8 KND92563.1 - 0.052 13.8 1.8 0.18 12.1 1.8 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Inhibitor_I34 PF10466.9 KND92563.1 - 0.98 10.1 5.8 7.7 7.2 0.3 2.8 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 DDHD PF02862.17 KND92565.1 - 4.2e-23 82.7 0.0 6.5e-14 52.6 0.0 2.6 1 1 0 2 2 2 2 DDHD domain Abhydrolase_1 PF00561.20 KND92565.1 - 0.042 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND92565.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Amidoligase_2 PF12224.8 KND92566.1 - 1.3e-15 57.7 0.0 5.3e-12 45.9 0.0 2.5 2 1 0 2 2 2 2 Putative amidoligase enzyme Hira PF07569.11 KND92567.1 - 9.9e-84 280.5 0.0 2.4e-83 279.2 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 KND92567.1 - 1.3e-32 111.2 21.8 5.5e-05 23.9 0.1 9.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92567.1 - 5.5e-17 61.8 0.0 0.024 14.9 0.0 6.9 3 1 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KND92567.1 - 3.5e-10 39.5 0.5 8.5e-10 38.3 0.5 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 KND92567.1 - 8.2e-06 25.6 0.2 16 5.6 0.0 5.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KND92567.1 - 0.0018 17.3 0.9 0.16 10.9 0.0 3.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Mcl1_mid PF12341.8 KND92567.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region IKI3 PF04762.12 KND92567.1 - 0.14 10.2 0.0 0.51 8.3 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Sugar_tr PF00083.24 KND92568.1 - 7e-72 242.7 12.3 1.4e-52 179.1 1.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KND92568.1 - 5.3e-22 78.2 18.2 2.4e-20 72.8 4.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Haem_degrading PF03928.14 KND92569.1 - 2.1e-33 114.9 0.5 3.1e-33 114.4 0.5 1.2 1 0 0 1 1 1 1 Haem-degrading Glyco_transf_15 PF01793.16 KND92572.1 - 4.7e-51 174.0 0.0 9.5e-38 130.3 0.0 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Sas10_Utp3 PF04000.15 KND92573.1 - 3e-13 50.2 0.2 3e-13 50.2 0.2 2.2 2 1 0 2 2 2 1 Sas10/Utp3/C1D family XRN_M PF17846.1 KND92573.1 - 0.19 10.6 3.9 0.21 10.5 3.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain NTP_transferase PF00483.23 KND92574.1 - 1.3e-30 106.8 0.0 1.8e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 KND92574.1 - 6e-07 28.9 12.2 5.1e-05 22.8 0.3 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KND92574.1 - 2.4e-06 28.0 0.0 3.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Dynamin_N PF00350.23 KND92575.1 - 1.2e-18 67.7 0.0 4.6e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND92575.1 - 3.7e-11 42.8 0.2 4.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KND92575.1 - 0.00052 20.1 0.7 0.0014 18.8 0.1 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain ABC_tran PF00005.27 KND92575.1 - 0.014 15.9 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 KND92575.1 - 0.016 15.3 0.0 0.18 11.9 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PHA_synth_III_E PF09712.10 KND92575.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Roc PF08477.13 KND92575.1 - 0.093 12.9 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KND92575.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein MFS_1 PF07690.16 KND92576.1 - 6.6e-16 58.2 14.9 3.5e-10 39.4 0.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3180 PF11377.8 KND92576.1 - 0.017 15.2 1.5 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) ABC2_membrane PF01061.24 KND92577.1 - 5.6e-79 264.4 64.5 2.3e-40 138.3 20.8 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KND92577.1 - 8.5e-37 126.7 0.0 2e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KND92577.1 - 3.5e-30 103.8 12.0 1.7e-26 91.9 0.2 3.7 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KND92577.1 - 2.6e-17 63.2 0.0 6.7e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 KND92577.1 - 2.1e-07 30.8 0.1 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND92577.1 - 5.9e-06 26.8 0.1 0.0016 18.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND92577.1 - 7.2e-06 26.0 0.1 0.0047 16.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KND92577.1 - 1.4e-05 25.3 1.1 0.0054 16.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KND92577.1 - 3.5e-05 24.3 0.1 0.0012 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND92577.1 - 3.9e-05 23.3 1.0 0.0025 17.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KND92577.1 - 0.00058 19.5 1.9 0.027 14.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 KND92577.1 - 0.00078 19.3 0.0 0.25 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND92577.1 - 0.00099 18.6 0.0 0.1 12.0 0.0 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND92577.1 - 0.0031 17.8 2.0 0.5 10.7 0.1 3.4 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KND92577.1 - 0.0042 17.1 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 KND92577.1 - 0.0044 17.0 1.5 1.3 9.0 0.2 2.5 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 KND92577.1 - 0.027 15.0 0.0 0.095 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 KND92577.1 - 0.039 13.7 1.3 1.6 8.4 0.4 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KND92577.1 - 0.058 13.8 0.1 13 6.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 KND92577.1 - 0.081 13.4 0.2 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KND92577.1 - 0.13 12.7 0.1 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KND92577.1 - 0.58 10.4 3.2 0.39 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.7 KND92577.1 - 10 5.3 29.2 0.43 9.8 10.3 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein FMN_red PF03358.15 KND92578.1 - 2.8e-05 23.9 0.0 3.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Glyoxalase PF00903.25 KND92579.1 - 1.4e-15 57.7 0.0 1.6e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KND92579.1 - 1.2e-05 25.5 0.4 0.0016 18.6 0.4 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KND92579.1 - 2.1e-05 24.7 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PTH2 PF01981.16 KND92580.1 - 2.8e-46 156.6 0.1 3.7e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Ribonuclease_3 PF00636.26 KND92581.1 - 8.6e-31 106.7 0.0 1.7e-15 57.5 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KND92581.1 - 6.4e-21 74.3 0.1 6e-19 68.0 0.0 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain DEAD PF00270.29 KND92581.1 - 2e-16 60.2 0.0 3.7e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND92581.1 - 2e-14 53.9 0.0 4.4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.6 KND92581.1 - 3e-13 50.0 0.0 0.00096 19.3 0.0 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like ResIII PF04851.15 KND92581.1 - 3.9e-13 49.8 0.0 8.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 KND92581.1 - 0.0082 16.8 0.1 0.019 15.7 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif DEAD_2 PF06733.15 KND92581.1 - 0.011 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_22 PF13401.6 KND92581.1 - 0.17 12.1 0.0 0.52 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RCC1 PF00415.18 KND92582.1 - 1.1e-13 51.5 0.2 5.1e-05 23.8 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND92582.1 - 6.7e-12 44.9 3.8 1.1e-07 31.5 0.3 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat AMP-binding PF00501.28 KND92583.1 - 9.6e-70 235.3 0.0 1.4e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Asp PF00026.23 KND92583.1 - 8.2e-55 186.4 0.0 1.1e-54 186.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AMP-binding_C PF13193.6 KND92583.1 - 4.4e-12 46.8 2.3 1.2e-11 45.4 2.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TAXi_N PF14543.6 KND92583.1 - 7e-11 42.7 0.3 7e-11 42.7 0.3 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KND92583.1 - 0.00035 21.1 0.1 14 6.4 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 KND92583.1 - 0.0024 18.4 0.1 27 5.4 0.0 3.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease CFEM PF05730.11 KND92584.1 - 6.3e-05 23.0 2.0 6.3e-05 23.0 2.0 3.2 3 0 0 3 3 3 1 CFEM domain Dynamin_N PF00350.23 KND92585.1 - 8.8e-37 126.7 0.2 1.7e-36 125.8 0.2 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND92585.1 - 1.5e-28 99.9 0.0 3.8e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KND92585.1 - 2.8e-06 27.4 0.1 1.4e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KND92585.1 - 0.022 14.9 0.3 0.4 10.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin GTPase effector domain AAA_21 PF13304.6 KND92585.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KND92585.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 KND92585.1 - 0.1 13.0 0.1 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KND92585.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 KND92586.1 - 0.00041 19.8 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KND92586.1 - 0.012 15.5 0.0 0.012 15.5 0.0 3.3 3 1 0 3 3 3 0 Phosphotransferase enzyme family HSDR_N_2 PF13588.6 KND92586.1 - 0.099 12.7 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) bVLRF1 PF18826.1 KND92587.1 - 1.7e-61 206.5 0.1 3e-61 205.7 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 KND92587.1 - 1.2e-05 25.4 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-C2H2_6 PF13912.6 KND92587.1 - 3.8 7.6 6.4 0.44 10.6 2.2 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger RPA43_OB PF17875.1 KND92587.1 - 6.5 7.4 7.4 2.8 8.6 2.8 2.7 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I DUF3435 PF11917.8 KND92588.1 - 2.6e-58 197.9 0.1 5.5e-58 196.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Methyltransf_23 PF13489.6 KND92589.1 - 1.3e-20 73.9 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND92589.1 - 1.1e-08 35.0 0.2 1.1e-07 31.8 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92589.1 - 7e-07 29.9 0.1 8.8e-06 26.3 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND92589.1 - 7e-05 23.4 0.0 0.00045 20.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND92589.1 - 0.014 16.1 0.0 0.09 13.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 KND92589.1 - 0.044 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase APH PF01636.23 KND92590.1 - 2.6e-14 53.7 0.4 4.1e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND92590.1 - 5.9e-05 22.7 0.0 8.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KND92590.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KND92590.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KND92590.1 - 0.2 11.0 0.0 8 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.25 KND92591.1 - 3.5e-13 49.5 0.0 4.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KND92591.1 - 4.3e-09 36.0 0.0 7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND92591.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND92591.1 - 6.3e-07 28.9 0.0 8e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KND92591.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 KND92591.1 - 0.0098 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KND92591.1 - 0.015 14.4 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 KND92591.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KND92591.1 - 0.04 12.7 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KND92591.1 - 0.17 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-C2H2 PF00096.26 KND92592.1 - 4.2e-10 39.5 30.7 0.0004 20.7 0.4 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND92592.1 - 1.6e-07 31.4 20.1 0.00011 22.4 1.6 4.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_aberr PF17017.5 KND92592.1 - 0.016 15.4 0.6 0.016 15.4 0.6 2.5 2 1 1 3 3 3 0 Aberrant zinc-finger zf-CCHC_2 PF13696.6 KND92592.1 - 0.019 14.8 1.3 0.053 13.4 1.3 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_4 PF13894.6 KND92592.1 - 0.079 13.8 0.3 0.079 13.8 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger Mito_carr PF00153.27 KND92593.1 - 1.4e-56 188.4 1.1 1.1e-18 66.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PH PF00169.29 KND92596.1 - 2.5e-27 95.5 4.6 9.1e-16 58.3 0.2 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 KND92596.1 - 1.5e-12 47.8 7.9 2.5e-06 27.8 0.8 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 KND92596.1 - 3.7e-10 40.2 3.8 3.3e-06 27.5 0.9 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 KND92596.1 - 5.8e-05 23.3 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KND92596.1 - 0.0041 17.2 2.4 0.027 14.5 0.3 2.7 2 1 1 3 3 3 1 PH domain PH_13 PF16652.5 KND92596.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 KND92597.1 - 9.5e-17 61.1 8.4 1.5e-07 32.0 0.2 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92597.1 - 6.6e-07 29.5 0.0 0.4 11.0 0.0 4.5 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ribonuc_red_sm PF00268.21 KND92598.1 - 8.9e-120 399.3 2.5 1.1e-119 399.0 2.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KND92599.1 - 3e-29 101.3 9.1 2e-23 82.6 0.2 2.4 2 1 1 3 3 3 2 Signal recognition particle 9 kDa protein (SRP9) DCP2 PF05026.13 KND92600.1 - 1.7e-31 108.3 0.8 3.8e-31 107.3 0.8 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KND92600.1 - 7.3e-17 61.6 0.0 2.4e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain DUF4112 PF13430.6 KND92601.1 - 9.2e-35 119.1 0.4 1.2e-34 118.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) MAGI_u5 PF16666.5 KND92602.1 - 0.32 11.2 4.5 0.56 10.4 4.5 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI RRM_occluded PF16842.5 KND92603.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF2076 PF09849.9 KND92604.1 - 0.00093 19.3 28.2 0.0044 17.1 28.4 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KND92604.1 - 0.0017 18.5 6.7 0.0028 17.8 6.7 1.4 1 0 0 1 1 1 1 CHCH domain Trypan_glycop_C PF10659.9 KND92604.1 - 0.0047 17.3 6.4 0.0073 16.7 6.4 1.2 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain COX17 PF05051.13 KND92604.1 - 0.58 10.6 3.3 0.48 10.8 0.6 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UBX PF00789.20 KND92605.1 - 2.9e-14 53.0 0.0 5.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 KND92605.1 - 0.028 14.6 0.3 0.17 12.1 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like DUF966 PF06136.13 KND92605.1 - 0.62 9.7 12.9 1 9.0 12.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PA26 PF04636.13 KND92605.1 - 1 8.2 4.9 1.8 7.4 4.9 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4407 PF14362.6 KND92605.1 - 6.3 6.0 18.4 9.9 5.4 18.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-5_eIF-2B PF01873.17 KND92606.1 - 1.2e-37 128.4 0.0 3.2e-37 127.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KND92606.1 - 1e-22 80.0 0.5 1e-22 80.0 0.5 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon efThoc1 PF11957.8 KND92607.1 - 6.7e-135 450.5 3.5 6.7e-135 450.5 3.5 1.9 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KND92607.1 - 1.4e-36 125.9 0.0 3.4e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.6 KND92607.1 - 0.00051 20.3 0.0 0.0042 17.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KND92607.1 - 0.00056 20.5 0.3 0.01 16.4 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KND92607.1 - 0.0012 19.3 2.9 0.0015 19.0 0.5 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KND92607.1 - 0.0021 18.1 0.1 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND92607.1 - 0.0078 16.4 0.3 0.066 13.4 0.3 2.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KND92607.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.7 5 0 0 5 5 5 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KND92607.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 KND92607.1 - 0.024 14.6 0.0 0.073 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KND92607.1 - 0.028 14.7 0.9 0.097 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KND92607.1 - 0.042 13.4 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 KND92607.1 - 0.085 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KND92607.1 - 0.12 12.5 0.2 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEAT PF02985.22 KND92608.1 - 1.1e-33 112.4 10.1 0.058 13.7 0.0 12.9 14 0 0 14 14 14 8 HEAT repeat HEAT_2 PF13646.6 KND92608.1 - 1.7e-28 98.8 5.9 5.4e-10 39.5 0.0 7.8 6 2 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 KND92608.1 - 1.8e-11 44.3 3.0 0.026 15.1 0.1 7.3 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KND92608.1 - 1.8e-10 41.3 4.1 0.14 12.7 0.1 6.5 6 1 1 7 7 7 4 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KND92608.1 - 1e-06 28.9 4.1 0.024 14.8 0.1 4.5 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 KND92608.1 - 1.6e-06 28.3 11.9 0.00011 22.3 0.2 5.8 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KND92608.1 - 0.00017 21.3 0.6 1.1 8.8 0.0 4.5 3 2 2 5 5 5 1 CLASP N terminal Adaptin_N PF01602.20 KND92608.1 - 0.00061 18.5 8.6 0.0012 17.5 0.1 3.7 4 1 0 4 4 4 1 Adaptin N terminal region Arm PF00514.23 KND92608.1 - 0.038 14.0 0.5 3.3 7.9 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KND92608.1 - 0.064 12.4 0.2 3 6.9 0.0 3.3 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) M11L PF11099.8 KND92608.1 - 0.065 13.5 0.1 25 5.1 0.0 3.1 2 1 0 3 3 3 0 Apoptosis regulator M11L like Ecm29 PF13001.7 KND92608.1 - 0.25 10.0 4.5 2.6 6.6 0.0 3.4 4 0 0 4 4 4 0 Proteasome stabiliser Proteasom_PSMB PF10508.9 KND92608.1 - 0.91 7.9 3.9 0.48 8.9 0.1 2.3 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Myotub-related PF06602.14 KND92609.1 - 2.3e-149 497.1 0.1 2.9e-149 496.8 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 KND92610.1 - 9.7e-25 86.9 0.1 5.5e-24 84.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KND92610.1 - 1.9e-10 40.4 0.0 3.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 KND92610.1 - 0.051 13.4 0.1 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 KND92610.1 - 0.13 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.14 KND92611.1 - 1.8e-98 329.3 13.7 5.7e-98 327.7 11.1 2.0 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 KND92611.1 - 0.00012 22.3 8.1 0.00012 22.3 8.1 3.1 2 2 0 2 2 2 1 EamA-like transporter family Transmemb_17 PF09799.9 KND92611.1 - 4.6 7.9 11.2 3 8.5 3.1 2.6 1 1 1 2 2 2 0 Predicted membrane protein p450 PF00067.22 KND92612.1 - 3.9e-43 147.9 0.0 1.7e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 BatA PF07584.11 KND92612.1 - 0.11 12.9 1.1 0.2 12.0 0.4 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CdvA PF18822.1 KND92613.1 - 0.013 15.3 0.0 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain eIF-6 PF01912.18 KND92614.1 - 7.2e-81 270.3 0.7 1e-80 269.8 0.7 1.2 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 KND92614.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 HupE / UreJ protein Methyltransf_31 PF13847.6 KND92615.1 - 5.2e-17 62.1 0.0 9.8e-17 61.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND92615.1 - 4.6e-09 36.9 0.0 9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92615.1 - 4.1e-08 33.8 0.0 1.4e-07 32.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND92615.1 - 2.4e-06 28.1 0.1 9.6e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND92615.1 - 3e-06 27.2 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND92615.1 - 0.00016 21.3 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KND92615.1 - 0.00029 20.9 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KND92615.1 - 0.00032 20.3 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 KND92615.1 - 0.00049 19.5 0.0 0.01 15.2 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 KND92615.1 - 0.016 15.5 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_4 PF02390.17 KND92615.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Acetyltransf_8 PF13523.6 KND92616.1 - 2e-47 160.6 1.4 3.1e-47 159.9 1.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND92616.1 - 0.052 14.2 0.2 0.11 13.2 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 KND92617.1 - 3.8e-54 184.1 0.0 5.2e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND92617.1 - 2e-37 128.9 0.0 3.2e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND92617.1 - 3.5e-05 23.1 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KND92617.1 - 9.7e-05 21.6 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KND92617.1 - 0.0015 18.7 0.1 0.0043 17.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND92617.1 - 0.027 14.1 0.2 0.081 12.5 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND92617.1 - 0.032 13.5 0.0 0.086 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND92617.1 - 0.2 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Aldedh PF00171.22 KND92618.1 - 6.2e-150 499.7 0.0 7.4e-150 499.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 KND92619.1 - 4.2e-225 747.1 0.0 3e-79 266.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KND92619.1 - 1.4e-174 581.1 0.0 1.8e-38 132.4 0.0 7.6 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.25 KND92619.1 - 1.9e-55 185.1 13.6 1.9e-10 40.9 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KND92619.1 - 1.5e-07 31.5 1.3 0.23 11.2 0.0 5.0 6 0 0 6 6 6 2 Wax ester synthase-like Acyl-CoA acyltransferase domain AMP-binding_C PF13193.6 KND92619.1 - 6e-07 30.3 0.0 0.99 10.4 0.1 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.15 KND92619.1 - 0.00032 19.5 0.0 7.4 5.1 0.0 4.0 4 0 0 4 4 4 3 Transferase family DUF1479 PF07350.12 KND92620.1 - 2e-91 306.8 0.0 2.4e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Zn_clus PF00172.18 KND92621.1 - 1.9e-06 27.9 8.7 3.2e-06 27.1 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSFA2_C PF14723.6 KND92621.1 - 0.093 12.6 2.9 0.2 11.5 2.9 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus VIR_N PF15912.5 KND92621.1 - 0.33 10.5 3.6 0.45 10.1 3.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal K_oxygenase PF13434.6 KND92622.1 - 2.4e-106 355.8 0.0 3.1e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KND92622.1 - 9.2e-07 28.4 0.1 0.00016 21.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND92622.1 - 8.2e-06 25.3 0.0 0.0014 17.9 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase IF-2B PF01008.17 KND92623.1 - 2.3e-23 82.8 0.0 3.1e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KND92623.1 - 1.5e-07 31.5 0.0 1.1e-06 28.8 0.1 2.3 2 1 0 2 2 2 1 NUDIX domain PALP PF00291.25 KND92623.1 - 0.029 13.8 1.8 0.031 13.7 0.1 1.9 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme INTS5_C PF14838.6 KND92623.1 - 0.094 11.3 0.0 0.24 10.0 0.0 1.5 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus RskA PF10099.9 KND92624.1 - 0.64 10.3 12.3 1.3 9.3 12.3 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CPT PF07931.12 KND92625.1 - 0.016 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KND92625.1 - 0.021 15.4 0.0 0.031 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Xpo1 PF08389.12 KND92626.1 - 1.1e-05 25.5 0.5 6.6e-05 23.0 0.1 2.6 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep_3 PF18806.1 KND92626.1 - 0.01 15.9 0.0 0.066 13.3 0.0 2.4 2 0 0 2 2 2 1 Importin 13 repeat Maf_N PF08383.11 KND92626.1 - 0.24 11.2 0.8 22 4.9 0.0 3.1 3 0 0 3 3 3 0 Maf N-terminal region Sec15 PF04091.12 KND92627.1 - 1.1e-112 376.6 5.1 2.4e-112 375.5 5.1 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KND92627.1 - 0.011 15.9 5.8 0.12 12.5 0.7 3.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF4201 PF13870.6 KND92627.1 - 0.054 13.2 6.7 0.027 14.2 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3510 PF12022.8 KND92627.1 - 0.14 12.6 4.2 9.6 6.6 0.1 3.3 2 2 3 5 5 5 0 Domain of unknown function (DUF3510) COG2 PF06148.11 KND92627.1 - 0.44 10.6 4.4 4.3 7.4 0.5 3.7 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc29 PF17082.5 KND92627.1 - 0.59 9.9 5.1 0.18 11.6 0.6 2.5 3 1 0 3 3 3 0 Spindle Pole Component 29 BORCS8 PF10167.9 KND92627.1 - 0.66 9.9 5.3 1.3 8.9 0.8 3.0 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 L27 PF02828.16 KND92627.1 - 5.6 6.8 6.4 1.3e+02 2.4 0.5 4.0 3 0 0 3 3 3 0 L27 domain Fcf2 PF08698.11 KND92628.1 - 3.3e-30 104.3 0.7 5e-30 103.8 0.1 1.6 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing SAM_2 PF07647.17 KND92629.1 - 3.3e-09 36.7 0.1 6.3e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KND92629.1 - 0.00011 22.5 0.2 0.00023 21.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 KND92629.1 - 0.087 12.9 0.2 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 KND92629.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Sad1_UNC PF07738.13 KND92630.1 - 6.9e-32 110.2 0.0 1.1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 KND92630.1 - 0.0086 16.2 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain AAA PF00004.29 KND92630.1 - 0.14 12.5 0.4 0.29 11.6 0.4 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Baculo_PEP_C PF04513.12 KND92630.1 - 3 7.9 5.5 2.4 8.2 2.4 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_11 PF13414.6 KND92631.1 - 8.5e-09 35.0 3.7 0.21 11.3 0.0 5.9 6 1 1 7 7 7 3 TPR repeat TPR_19 PF14559.6 KND92631.1 - 5.5e-08 33.2 14.4 0.00022 21.7 0.1 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND92631.1 - 2.3e-07 31.1 31.2 0.093 13.6 0.2 10.0 7 2 2 10 10 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 KND92631.1 - 9.3e-07 29.1 10.9 0.1 12.9 0.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND92631.1 - 4e-06 26.5 28.6 0.5 10.6 0.0 10.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND92631.1 - 7e-06 26.6 33.9 1.9e-05 25.2 0.2 6.5 8 2 2 10 10 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 KND92631.1 - 1.1e-05 25.5 1.4 3.2 8.3 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND92631.1 - 5.8e-05 23.3 18.8 0.14 12.4 0.1 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND92631.1 - 0.00064 19.7 8.9 2.9 8.3 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND92631.1 - 0.0027 17.4 13.9 30 4.6 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND92631.1 - 0.0078 16.2 15.4 1.3 9.2 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF4407 PF14362.6 KND92631.1 - 0.023 14.1 1.0 0.045 13.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alkyl_sulf_dimr PF14863.6 KND92631.1 - 0.045 14.2 0.8 16 5.9 0.0 3.0 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation UTP15_C PF09384.10 KND92631.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 UTP15 C terminal BTAD PF03704.17 KND92631.1 - 0.42 11.0 6.5 6.6 7.2 0.1 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain CBFD_NFYB_HMF PF00808.23 KND92632.1 - 2.6e-19 69.3 0.5 4.1e-19 68.6 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND92632.1 - 7.1e-16 58.8 0.6 1.8e-15 57.4 0.3 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KND92632.1 - 0.045 14.1 0.1 0.083 13.2 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 KND92632.1 - 0.12 12.4 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mito_carr PF00153.27 KND92633.1 - 2.7e-55 184.3 0.3 9.2e-20 70.4 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.17 KND92633.1 - 6.8e-20 71.1 8.2 1.2e-19 70.3 8.2 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.22 KND92634.1 - 1.9e-56 187.8 0.1 5.7e-21 74.1 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND92634.1 - 3.3e-08 33.3 0.0 0.032 14.1 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KND92634.1 - 5.9e-08 32.4 0.0 0.2 11.2 0.0 4.2 2 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND92634.1 - 8.3e-05 22.5 0.0 1.7 8.7 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KND92634.1 - 0.00041 20.4 0.1 1.2 9.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 KND92634.1 - 0.00095 19.3 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 1 RRM-like domain Cas_Cas2CT1978 PF09707.10 KND92634.1 - 0.009 16.1 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RNA_bind PF08675.11 KND92634.1 - 0.048 13.7 0.1 13 5.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain UL73_N PF12522.8 KND92635.1 - 7.8 6.3 8.2 13 5.7 5.0 2.3 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal Tubulin_3 PF14881.6 KND92636.1 - 6.9e-76 254.0 0.1 1.1e-75 253.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 KND92636.1 - 1e-40 138.7 0.1 1.7e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 KND92636.1 - 1.5e-05 25.3 0.0 0.0046 17.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain DUF1839 PF08893.10 KND92636.1 - 0.02 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1839) AhpC-TSA_2 PF13911.6 KND92637.1 - 4.1e-08 33.3 0.0 6.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KND92637.1 - 0.00015 21.7 0.0 0.00025 21.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND92637.1 - 0.012 15.3 0.0 0.2 11.4 0.0 2.2 1 1 0 1 1 1 0 Redoxin TPP_enzyme_M PF00205.22 KND92637.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Septin PF00735.18 KND92638.1 - 6.6e-11 42.0 0.0 2.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 Septin Pkinase PF00069.25 KND92639.1 - 6.1e-77 258.5 0.0 7.3e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92639.1 - 1.7e-37 129.1 0.0 2.5e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND92639.1 - 0.00097 18.2 0.0 0.018 14.0 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND92639.1 - 0.043 13.2 0.1 0.09 12.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND92639.1 - 0.098 12.6 2.2 0.31 10.9 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 KND92640.1 - 2.1e-10 40.4 0.0 2.4e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase zf-NOSIP PF15906.5 KND92641.1 - 1e-09 38.4 0.8 4e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 KND92641.1 - 1e-07 31.8 8.6 1.5e-05 24.9 1.8 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KND92641.1 - 6.3e-07 29.6 14.2 0.00028 21.1 6.2 2.8 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 KND92641.1 - 4.8e-06 26.4 5.2 4.8e-06 26.4 5.2 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KND92641.1 - 4.5e-05 23.2 14.3 0.0061 16.4 6.1 3.0 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND92641.1 - 0.00013 21.7 15.2 0.0054 16.6 7.2 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND92641.1 - 0.00033 20.7 16.5 0.0092 16.1 8.1 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KND92641.1 - 0.00056 19.7 3.6 0.00056 19.7 3.6 3.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KND92641.1 - 0.0006 19.9 6.8 0.012 15.8 4.0 2.6 2 1 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 KND92641.1 - 0.04 14.1 1.5 0.04 14.1 1.5 2.9 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain DZR PF12773.7 KND92641.1 - 0.88 9.6 15.3 9.3 6.4 7.6 3.5 2 1 0 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 KND92641.1 - 3.1 7.9 6.5 0.56 10.3 2.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 KND92641.1 - 3.7 6.8 11.6 0.092 12.1 1.7 2.4 2 1 1 3 3 3 0 Rtf2 RING-finger Mito_carr PF00153.27 KND92642.1 - 8.3e-33 112.2 0.8 1.7e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein SCA7 PF08313.12 KND92643.1 - 1.9e-31 107.7 0.1 5.3e-31 106.3 0.1 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Lipase_GDSL_2 PF13472.6 KND92643.1 - 8.9e-12 45.8 0.7 1.1e-10 42.2 0.0 2.9 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND92643.1 - 0.0019 18.2 0.0 0.0062 16.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OrsD PF12013.8 KND92643.1 - 0.13 12.7 2.4 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D CDC45 PF02724.14 KND92643.1 - 1.4 7.1 11.9 2.1 6.6 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Forkhead PF00250.18 KND92644.1 - 2.5e-32 111.0 0.5 4.3e-32 110.2 0.5 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KND92644.1 - 1.3e-09 38.3 0.0 3.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND92644.1 - 0.00021 21.6 0.0 0.00042 20.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 KND92644.1 - 0.11 12.8 0.0 0.65 10.3 0.0 2.0 2 0 0 2 2 2 0 FHA domain PAP_central PF04928.17 KND92645.1 - 3.2e-110 367.0 0.0 4.2e-110 366.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KND92645.1 - 1.2e-65 220.3 0.3 2.3e-65 219.4 0.3 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KND92645.1 - 3.8e-09 36.7 0.1 8.5e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ribosomal_S21 PF01165.20 KND92645.1 - 0.024 14.3 0.4 0.07 12.9 0.4 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 Polbeta PF18765.1 KND92645.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase SPOC PF07744.13 KND92646.1 - 2.4e-26 92.5 0.0 3.9e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KND92646.1 - 3.9e-20 72.4 1.9 7.6e-20 71.5 0.3 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KND92646.1 - 2.1e-08 33.9 9.5 3.9e-08 33.1 9.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KND92646.1 - 1.9 8.1 6.9 3.6 7.2 6.9 1.4 1 0 0 1 1 1 0 PHD-finger CMS1 PF14617.6 KND92647.1 - 3.6e-83 278.8 1.3 3.9e-83 278.7 1.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KND92647.1 - 6.3e-08 32.6 0.0 1.1e-07 31.8 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Consortin_C PF15281.6 KND92647.1 - 0.039 13.9 0.1 0.079 13.0 0.1 1.5 1 0 0 1 1 1 0 Consortin C-terminus CHD5 PF04420.14 KND92648.1 - 1.8e-60 203.4 0.4 2.4e-60 203.0 0.4 1.2 1 0 0 1 1 1 1 CHD5-like protein ImpA_N PF06812.12 KND92648.1 - 0.017 15.2 0.1 0.031 14.4 0.1 1.4 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system MMS19_N PF14500.6 KND92648.1 - 0.036 13.7 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Phlebovirus_NSM PF07246.11 KND92648.1 - 0.092 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Abhydrolase_6 PF12697.7 KND92649.1 - 1e-14 55.7 9.4 1.3e-14 55.3 9.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND92649.1 - 1.5e-12 47.7 0.9 3.9e-12 46.4 0.9 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KND92649.1 - 1.2e-07 31.8 0.1 0.0089 15.8 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KND92649.1 - 3.2e-07 29.9 0.3 4.4e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KND92649.1 - 0.0002 21.5 0.1 0.00041 20.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 KND92649.1 - 0.0015 18.2 0.1 0.0024 17.5 0.1 1.5 1 1 0 1 1 1 1 Putative esterase FAD_binding_3 PF01494.19 KND92650.1 - 1.1e-23 84.1 0.6 4e-11 42.8 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KND92650.1 - 1.6e-05 24.1 0.0 0.00012 21.2 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KND92650.1 - 1.7e-05 24.6 0.7 0.0069 16.0 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KND92650.1 - 0.00028 20.1 0.0 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KND92650.1 - 0.00056 20.1 0.1 0.0018 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND92650.1 - 0.00078 18.8 0.0 0.0017 17.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND92650.1 - 0.0013 17.9 0.1 0.0043 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KND92650.1 - 0.0013 17.5 0.1 0.002 16.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KND92650.1 - 0.0026 18.3 0.2 0.012 16.2 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KND92650.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 KND92650.1 - 0.12 11.2 0.0 5.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KND92650.1 - 0.22 11.4 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_C12 PF01088.21 KND92651.1 - 1.8e-49 168.3 0.0 2.1e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sugar_tr PF00083.24 KND92652.1 - 2.3e-111 372.8 18.3 2.8e-111 372.6 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND92652.1 - 3.3e-24 85.5 31.7 3.3e-24 85.5 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KND92652.1 - 0.0054 15.6 0.4 0.0054 15.6 0.4 2.3 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF2420 PF10336.9 KND92653.1 - 0.0011 19.0 3.5 0.067 13.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2420) ANAPC4 PF12896.7 KND92654.1 - 2.5e-67 226.3 0.0 4.1e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Adap_comp_sub PF00928.21 KND92654.1 - 7.9e-15 54.9 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ANAPC4_WD40 PF12894.7 KND92654.1 - 8.5e-11 42.0 0.0 8.5e-10 38.8 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Clat_adaptor_s PF01217.20 KND92654.1 - 9.8e-08 32.0 0.1 2e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 KND92655.1 - 1.3e-36 124.3 0.0 4.9e-12 45.5 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND92655.1 - 1.2e-15 57.1 0.0 0.0092 15.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 KND92655.1 - 1.6e-08 34.1 2.2 1.6e-08 34.1 2.2 3.4 4 0 0 4 4 4 1 Putative RRM domain RRM_7 PF16367.5 KND92655.1 - 7e-06 26.1 0.0 0.065 13.4 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 KND92655.1 - 5.5e-05 23.1 0.0 0.034 14.0 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 KND92655.1 - 0.016 15.2 0.0 12 6.0 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KND92655.1 - 0.047 13.5 0.0 0.98 9.2 0.0 3.0 3 1 1 4 4 4 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 KND92655.1 - 0.13 12.3 0.5 0.51 10.4 0.0 2.2 3 0 0 3 3 3 0 RNA binding domain RRM_3 PF08777.11 KND92655.1 - 0.13 12.3 0.1 0.76 9.9 0.1 2.2 3 0 0 3 3 3 0 RNA binding motif Ser_hydrolase PF06821.13 KND92657.1 - 0.16 11.8 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.8 KND92657.1 - 0.18 11.1 0.1 0.74 9.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 KND92657.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase His_Phos_2 PF00328.22 KND92658.1 - 2.2e-11 43.8 0.0 5.7e-09 35.8 0.0 3.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gtr1_RagA PF04670.12 KND92661.1 - 3.4e-70 236.0 0.1 4.2e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KND92661.1 - 0.0048 16.4 0.0 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND92661.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 KND92661.1 - 0.019 15.3 0.0 0.054 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 KND92661.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Yippee-Mis18 PF03226.14 KND92663.1 - 2.1e-16 60.0 0.7 2.4e-16 59.9 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KND92663.1 - 0.0033 17.6 1.6 0.0051 17.0 1.6 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 KND92663.1 - 0.016 15.5 2.8 0.037 14.4 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RNA_POL_M_15KD PF02150.16 KND92663.1 - 0.095 12.6 1.4 10 6.1 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Evr1_Alr PF04777.13 KND92663.1 - 0.1 13.1 3.7 0.23 11.9 0.8 2.2 1 1 1 2 2 2 0 Erv1 / Alr family DUF4452 PF14618.6 KND92664.1 - 5.4e-78 260.7 11.0 6.5e-78 260.4 11.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Abhydrolase_6 PF12697.7 KND92665.1 - 5.7e-11 43.4 6.0 5.7e-11 43.4 6.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND92665.1 - 6.5e-10 38.7 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KND92665.1 - 7.7e-10 38.8 0.3 3.9e-09 36.5 0.4 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold ATP_bind_3 PF01171.20 KND92667.1 - 9.1e-38 129.8 0.0 3.5e-36 124.7 0.0 2.2 1 1 0 1 1 1 1 PP-loop family HSR PF03172.13 KND92668.1 - 0.063 13.4 0.2 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 HSR domain DUF4097 PF13349.6 KND92669.1 - 4.2e-06 26.3 2.3 0.077 12.3 0.0 3.2 2 1 1 3 3 3 3 Putative adhesin TT1725 PF18324.1 KND92670.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein TT1725 Cyclin_N PF00134.23 KND92671.1 - 3.7e-11 42.9 0.4 1.4e-10 41.0 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KND92671.1 - 0.0059 17.0 0.6 0.023 15.1 0.1 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Turandot PF07240.11 KND92671.1 - 0.14 12.2 0.2 0.29 11.1 0.2 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Mito_carr PF00153.27 KND92672.1 - 7.6e-71 234.1 4.7 1.2e-25 89.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KND92672.1 - 2e-22 79.4 6.6 7.4e-12 45.6 1.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KND92672.1 - 1.8e-19 67.7 12.1 4.6e-06 25.8 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 KND92672.1 - 1.8e-17 61.9 13.3 3.2e-05 23.2 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KND92672.1 - 4.6e-17 60.4 12.5 2.8e-06 26.8 0.2 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KND92672.1 - 2.6e-10 40.0 9.8 1.5e-05 24.8 0.6 3.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KND92672.1 - 2.5e-07 31.0 0.2 0.0016 18.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Serine_protease PF18405.1 KND92672.1 - 0.0027 16.9 2.3 1.5 7.9 0.1 3.5 3 1 1 4 4 4 2 Gammaproteobacterial serine protease EF-hand_9 PF14658.6 KND92672.1 - 0.0043 17.3 0.1 2.1 8.7 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain Alpha-2-MRAP_C PF06401.11 KND92672.1 - 0.092 12.7 0.3 0.15 12.0 0.3 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain EF-hand_14 PF17959.1 KND92672.1 - 0.16 12.3 1.2 0.88 10.0 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 KND92672.1 - 0.24 11.3 1.2 19 5.2 0.0 3.0 4 0 0 4 4 4 0 EF hand SET PF00856.28 KND92673.1 - 0.0098 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 SET domain HSP70 PF00012.20 KND92674.1 - 2.9e-08 32.4 0.1 2.1e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 KND92674.1 - 0.0025 18.2 0.0 0.055 13.9 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA Pkinase PF00069.25 KND92675.1 - 1.4e-55 188.5 0.0 2.1e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92675.1 - 1.5e-31 109.6 0.0 7.1e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND92675.1 - 0.0034 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KND92675.1 - 0.026 13.5 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KND92675.1 - 0.18 11.1 0.6 0.29 10.4 0.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Stc1 PF12898.7 KND92676.1 - 3.5e-19 69.1 3.3 3.5e-19 69.1 3.3 1.7 2 0 0 2 2 2 1 Stc1 domain Utp12 PF04003.12 KND92677.1 - 2.2e-22 79.4 0.1 3.8e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.25 KND92678.1 - 3.2e-26 91.2 0.0 6.6e-17 61.4 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KND92678.1 - 1.4e-14 54.0 1.5 3.4e-14 52.7 1.5 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation NUDIX PF00293.28 KND92679.1 - 2.8e-05 24.2 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KND92679.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Beta-lactamase PF00144.24 KND92680.1 - 6.2e-47 160.4 4.9 1.5e-46 159.2 4.9 1.5 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KND92680.1 - 0.046 13.3 0.0 8.8 5.9 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family BCDHK_Adom3 PF10436.9 KND92681.1 - 6.3e-67 224.5 0.0 9.2e-67 223.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KND92681.1 - 1e-09 38.9 0.0 2.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serine_rich PF08824.10 KND92681.1 - 0.059 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain HATPase_c_3 PF13589.6 KND92681.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NBP1 PF08537.10 KND92682.1 - 0.036 13.5 0.1 0.036 13.5 0.1 2.1 2 1 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF2203 PF09969.9 KND92682.1 - 0.35 11.6 2.0 0.82 10.4 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4094 PF13334.6 KND92682.1 - 0.42 11.0 3.6 4.4 7.8 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) MFS_1 PF07690.16 KND92683.1 - 2.2e-37 128.8 41.5 2.2e-37 128.8 41.5 1.8 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND92683.1 - 3.5e-10 39.3 14.8 3.5e-10 39.3 14.8 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter AAA_12 PF13087.6 KND92684.1 - 0.041 13.5 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain Gon7 PF08738.10 KND92687.1 - 2.7e-11 43.5 0.6 4.5e-10 39.6 0.0 2.0 1 1 1 2 2 2 2 Gon7 family DUF1582 PF07621.11 KND92687.1 - 0.0063 16.4 0.4 0.01 15.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1582) MFS_1 PF07690.16 KND92688.1 - 2e-37 129.0 13.6 2.8e-35 121.9 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 KND92688.1 - 0.042 14.1 0.8 13 6.0 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) Proton_antipo_N PF00662.20 KND92688.1 - 0.11 12.6 2.4 1.1 9.4 0.6 3.3 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Phage_holin_2_4 PF16082.5 KND92688.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.6 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF4579 PF15158.6 KND92688.1 - 3.2 7.5 4.5 4.3 7.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4579) Ribonuclease PF00545.20 KND92689.1 - 1.1e-09 38.9 0.0 1.5e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Beta-lactamase PF00144.24 KND92691.1 - 3.5e-50 171.1 0.1 5.1e-50 170.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KND92691.1 - 1.2e-13 51.4 0.1 2.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ABC_membrane PF00664.23 KND92692.1 - 5.1e-91 305.1 29.7 1.6e-47 162.5 11.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND92692.1 - 3e-60 202.7 0.0 3.2e-30 105.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND92692.1 - 7.3e-11 41.9 1.6 0.013 14.9 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND92692.1 - 5e-08 32.6 0.3 0.0068 16.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KND92692.1 - 7.3e-08 32.8 0.1 0.0024 18.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND92692.1 - 2.7e-07 31.1 2.9 0.00013 22.4 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 KND92692.1 - 1.1e-06 27.7 0.0 0.0078 15.0 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 KND92692.1 - 1.8e-06 28.0 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KND92692.1 - 0.00018 21.1 0.1 0.28 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KND92692.1 - 0.00019 21.3 0.0 0.36 10.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND92692.1 - 0.00036 21.1 0.3 0.22 12.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND92692.1 - 0.00053 19.8 2.9 0.62 9.7 0.5 3.8 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.6 KND92692.1 - 0.00067 19.8 4.1 0.7 10.2 0.1 4.5 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KND92692.1 - 0.0028 17.7 0.2 0.68 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KND92692.1 - 0.0042 16.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KND92692.1 - 0.0044 17.3 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND92692.1 - 0.011 16.3 0.0 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KND92692.1 - 0.013 15.4 0.1 0.87 9.5 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 KND92692.1 - 0.014 14.6 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KND92692.1 - 0.014 15.5 0.7 3.8 7.6 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KND92692.1 - 0.015 14.6 0.1 2.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 KND92692.1 - 0.025 14.7 0.3 6.1 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KND92692.1 - 0.03 13.8 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 KND92692.1 - 0.044 13.9 0.4 9.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 KND92692.1 - 0.15 11.7 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KND92692.1 - 0.16 12.0 0.1 9.8 6.2 0.0 3.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 KND92692.1 - 0.21 11.5 0.5 14 5.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KND92692.1 - 0.32 11.4 1.0 1.1e+02 3.2 0.0 3.6 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AA_permease PF00324.21 KND92693.1 - 4.2e-102 342.2 40.4 4.8e-102 342.0 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND92693.1 - 9.6e-26 90.6 42.6 1.1e-25 90.3 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4050 PF13259.6 KND92694.1 - 1.1e-55 188.8 0.1 1.1e-55 188.8 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) AMP-binding PF00501.28 KND92695.1 - 1.8e-80 270.6 0.0 3.6e-76 256.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KND92695.1 - 1.1e-48 166.0 0.0 1e-28 100.3 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KND92695.1 - 1.7e-26 92.3 0.1 6.4e-12 45.7 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.16 KND92695.1 - 0.048 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain MDMPI_N PF11716.8 KND92695.1 - 0.059 14.1 5.4 0.067 13.9 1.6 3.2 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain MRP-S22 PF10245.9 KND92696.1 - 0.21 11.3 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S22 Pex14_N PF04695.13 KND92697.1 - 1.4e-34 120.0 0.2 1.4e-34 120.0 0.2 2.1 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.12 KND92698.1 - 2e-27 95.8 4.7 2e-27 95.8 4.7 3.5 4 0 0 4 4 4 1 PAPA-1-like conserved region BSP_II PF05432.11 KND92698.1 - 1.9 8.1 39.0 2.9 7.5 39.0 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ras PF00071.22 KND92699.1 - 1.6e-61 206.6 0.1 1.9e-61 206.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND92699.1 - 2e-33 115.1 0.1 2.9e-33 114.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92699.1 - 1.4e-11 44.2 0.0 1.8e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND92699.1 - 8.9e-07 29.0 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND92699.1 - 0.00029 20.8 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KND92699.1 - 0.0015 18.1 0.1 0.009 15.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KND92699.1 - 0.0038 17.5 0.0 0.03 14.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND92699.1 - 0.0077 16.6 0.1 0.014 15.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 KND92699.1 - 0.0094 15.3 0.0 0.014 14.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 KND92699.1 - 0.024 14.7 0.1 0.06 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND92699.1 - 0.045 14.3 0.1 0.063 13.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KND92699.1 - 0.061 13.1 0.5 0.09 12.6 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 KND92699.1 - 0.065 12.6 0.0 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SRPRB PF09439.10 KND92699.1 - 0.068 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KND92699.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Chromo PF00385.24 KND92700.1 - 4.7e-07 29.6 0.2 1.4e-06 28.1 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Sec31 PF11549.8 KND92700.1 - 0.092 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein transport protein SEC31 F-box-like PF12937.7 KND92701.1 - 0.0018 18.1 0.0 0.006 16.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND92701.1 - 0.02 14.8 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KND92701.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 F-box Brix PF04427.18 KND92702.1 - 1e-37 130.1 0.0 1.5e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain NACHT PF05729.12 KND92704.1 - 1.1e-11 44.9 1.9 1.3e-10 41.4 0.2 2.9 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.6 KND92704.1 - 5.1e-08 33.5 0.1 2.6e-07 31.2 0.1 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND92704.1 - 5.9e-07 29.8 0.1 3.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.7 KND92704.1 - 6.3e-07 29.9 0.0 0.00038 21.0 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND92704.1 - 0.00017 21.8 0.6 20 5.6 0.1 5.4 4 1 1 5 5 5 0 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 KND92704.1 - 0.0064 15.8 0.0 0.033 13.4 0.0 2.0 1 1 1 2 2 2 1 KAP family P-loop domain Ank_3 PF13606.6 KND92704.1 - 0.0066 16.9 0.2 63 4.6 0.0 5.0 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.6 KND92704.1 - 0.0076 16.8 0.2 0.82 10.3 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) LAGLIDADG_3 PF14528.6 KND92704.1 - 0.064 13.6 0.0 9.2 6.7 0.0 2.8 2 0 0 2 2 2 0 LAGLIDADG-like domain RGS-like PF09128.11 KND92704.1 - 0.082 12.6 0.6 0.3 10.8 0.1 2.1 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF3293 PF11697.8 KND92704.1 - 0.21 12.1 0.6 0.91 10.0 0.1 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3293) DUF676 PF05057.14 KND92705.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Mpv17_PMP22 PF04117.12 KND92707.1 - 2.7e-14 53.1 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family SET PF00856.28 KND92708.1 - 2.1e-11 44.5 0.1 1.2e-10 42.0 0.0 2.2 2 1 0 2 2 2 1 SET domain Noelin-1 PF12308.8 KND92708.1 - 0.077 13.0 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein Complex1_LYR PF05347.15 KND92709.1 - 0.011 15.7 0.3 0.023 14.8 0.3 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND92709.1 - 0.024 15.4 0.1 0.03 15.1 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 KND92710.1 - 3e-32 111.5 1.6 3e-32 111.5 1.6 3.9 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KND92710.1 - 2.9e-19 68.9 2.6 2.9e-19 68.9 2.6 2.4 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.19 KND92710.1 - 6 4.7 15.9 0.044 11.7 7.8 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Sterol_MT_C PF08498.10 KND92711.1 - 2e-29 101.6 0.2 3.6e-29 100.8 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KND92711.1 - 8.5e-21 74.4 0.0 1.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92711.1 - 1.2e-19 70.8 0.0 3.1e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND92711.1 - 6.5e-18 65.0 0.0 9.1e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND92711.1 - 5e-13 49.0 0.0 7.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KND92711.1 - 1.6e-11 44.3 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND92711.1 - 3.1e-11 43.1 0.0 5.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KND92711.1 - 1e-09 39.0 0.0 2.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND92711.1 - 0.00014 21.7 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KND92711.1 - 0.00066 19.2 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 KND92711.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 KND92711.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 KND92711.1 - 0.0044 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 KND92711.1 - 0.0065 15.1 0.0 0.0085 14.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 KND92711.1 - 0.0092 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB RrnaAD PF00398.20 KND92711.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Hormone_3 PF00159.18 KND92711.1 - 0.077 13.1 0.7 0.21 11.7 0.7 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide RRM_1 PF00076.22 KND92712.1 - 1e-09 38.1 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND92712.1 - 0.0019 18.1 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KND92712.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KND92712.1 - 0.0097 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif MFS_1 PF07690.16 KND92713.1 - 9.6e-30 103.7 65.2 4.2e-22 78.6 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transket_pyr PF02779.24 KND92714.1 - 5.7e-62 208.5 0.0 9.4e-62 207.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KND92714.1 - 6.5e-58 196.0 0.0 9.8e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KND92714.1 - 8.8e-55 184.6 0.1 1.4e-54 183.9 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KND92714.1 - 7.3e-20 70.3 1.2 1.5e-19 69.3 1.2 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus WD40 PF00400.32 KND92715.1 - 2.3e-24 85.2 12.2 1.7e-08 35.0 0.1 7.1 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92715.1 - 0.00015 22.0 0.1 6.2 7.2 0.0 4.6 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND92715.1 - 0.013 14.5 0.2 0.13 11.2 0.1 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BSD PF03909.17 KND92716.1 - 5.8e-31 106.3 3.8 6.5e-15 54.9 0.1 2.8 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 KND92716.1 - 2.6e-25 88.6 0.2 7e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Cas_APE2256 PF09651.10 KND92716.1 - 0.11 12.3 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) AAA PF00004.29 KND92717.1 - 7.3e-38 130.0 0.0 1.8e-37 128.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND92717.1 - 5e-10 39.0 0.2 1.2e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KND92717.1 - 5.6e-06 26.2 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND92717.1 - 5.1e-05 23.7 0.1 0.0021 18.5 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND92717.1 - 0.0001 22.6 0.3 0.04 14.2 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KND92717.1 - 0.00081 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KND92717.1 - 0.0035 17.4 0.1 0.0083 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KND92717.1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KND92717.1 - 0.0065 16.6 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KND92717.1 - 0.0084 15.5 0.1 0.021 14.2 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KND92717.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KND92717.1 - 0.013 16.0 0.0 0.051 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND92717.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KND92717.1 - 0.047 13.3 0.2 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KND92717.1 - 0.053 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 KND92717.1 - 0.06 12.7 0.0 1 8.7 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 KND92717.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KND92717.1 - 0.068 13.7 0.0 0.52 10.8 0.0 2.4 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 KND92717.1 - 0.12 12.2 0.1 0.37 10.7 0.1 1.8 2 0 0 2 2 1 0 NACHT domain AAA_2 PF07724.14 KND92717.1 - 0.13 12.4 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 KND92717.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hydin_ADK PF17213.3 KND92717.1 - 0.24 11.6 0.3 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Zn_clus PF00172.18 KND92718.1 - 4.4e-07 29.9 10.8 8e-07 29.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND92718.1 - 0.00017 20.5 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TEX15 PF15326.6 KND92718.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Testis expressed sequence 15 ATP-synt_ab PF00006.25 KND92719.1 - 4.2e-62 209.6 0.0 6.3e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KND92719.1 - 2.1e-22 79.4 0.4 5.5e-22 78.1 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 KND92719.1 - 0.011 15.6 0.4 0.031 14.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KND92719.1 - 0.022 14.0 0.3 0.082 12.1 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KND92719.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KND92719.1 - 0.039 13.3 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 KND92719.1 - 0.055 13.9 0.0 0.64 10.4 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KND92719.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KND92719.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KND92719.1 - 0.15 12.4 0.1 0.5 10.7 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain T3SS_ATPase_C PF18269.1 KND92719.1 - 0.18 11.7 0.3 1 9.2 0.3 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_19 PF13245.6 KND92719.1 - 0.35 11.2 3.8 0.48 10.8 0.2 2.5 3 0 0 3 3 3 0 AAA domain Alpha-amylase_C PF02806.18 KND92720.1 - 5.8e-26 90.8 0.0 1.9e-25 89.1 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KND92720.1 - 1.3e-18 67.1 0.0 4.9e-18 65.3 0.0 2.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KND92720.1 - 1.5e-14 54.3 0.2 4.6e-11 42.9 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 KND92720.1 - 0.028 14.6 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Cellulase PF00150.18 KND92720.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) hDGE_amylase PF14701.6 KND92720.1 - 0.14 11.2 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 KND92721.1 - 8.5e-32 110.6 0.0 2.3e-31 109.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KND92721.1 - 6.5e-12 46.0 0.1 1.5e-11 44.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KND92721.1 - 2.8e-10 40.1 0.0 8.3e-10 38.6 0.0 1.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KND92721.1 - 3.2e-06 27.2 0.0 7.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 KND92721.1 - 6.3e-05 22.2 0.0 0.0002 20.5 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 KND92721.1 - 0.00065 20.0 1.8 0.0024 18.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND92721.1 - 0.0035 17.8 0.1 0.011 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KND92721.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 KND92721.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KND92721.1 - 0.02 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KND92721.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KND92721.1 - 0.093 13.3 0.5 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KND92721.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KND92721.1 - 0.12 11.8 0.0 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KND92721.1 - 0.18 11.5 0.0 0.48 10.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2058 PF09831.9 KND92721.1 - 0.2 11.8 1.5 0.32 11.1 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ABC_tran PF00005.27 KND92721.1 - 0.25 11.9 0.5 0.54 10.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter COX4 PF02936.14 KND92722.1 - 2.6e-48 163.5 0.1 3e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV OTT_1508_deam PF14441.6 KND92723.1 - 6.4e-19 67.7 0.1 1.2e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase FAP206 PF12018.8 KND92723.1 - 0.037 13.6 0.6 0.06 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function NADH-u_ox-rdase PF10785.9 KND92724.1 - 1e-28 99.8 0.3 2e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KND92724.1 - 5.6e-24 83.9 0.0 7.9e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 KND92725.1 - 9.2e-32 108.9 0.1 1.4e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 GMC_oxred_N PF00732.19 KND92727.1 - 8.6e-60 202.6 0.0 1.9e-59 201.5 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND92727.1 - 1.6e-34 119.5 0.0 2.7e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KND92727.1 - 1.3e-05 24.4 1.4 0.00019 20.6 1.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KND92727.1 - 0.0088 15.2 5.2 0.92 8.5 3.3 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KND92727.1 - 0.02 14.2 0.1 0.049 12.9 0.1 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KND92727.1 - 0.034 13.7 7.6 0.097 12.2 7.6 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND92727.1 - 0.053 13.7 3.7 0.1 12.9 2.8 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND92727.1 - 0.12 11.6 0.6 0.21 10.8 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND92727.1 - 0.28 10.0 1.1 0.42 9.4 1.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KND92727.1 - 0.4 9.3 1.5 1.5 7.4 1.2 1.8 2 0 0 2 2 2 0 HI0933-like protein Transp_cyt_pur PF02133.15 KND92728.1 - 1.5e-23 83.3 41.7 2.7e-23 82.5 41.7 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF962 PF06127.11 KND92728.1 - 0.00051 20.1 0.0 1.2 9.2 0.0 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF962) NTP_transf_9 PF04248.12 KND92731.1 - 7e-31 106.0 0.2 9.3e-31 105.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Ist1 PF03398.14 KND92732.1 - 0.00014 21.9 4.2 0.0002 21.3 4.2 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Snf7 PF03357.21 KND92732.1 - 0.00026 20.6 26.4 0.00026 20.6 26.4 1.7 1 1 1 2 2 2 1 Snf7 CEL_III_C PF18054.1 KND92732.1 - 0.66 10.0 7.6 1 9.4 7.6 1.5 1 0 0 1 1 1 0 CEL-III C-terminal RFamide_26RFa PF11109.8 KND92732.1 - 2 8.9 12.2 0.17 12.4 1.6 2.2 1 1 1 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 DUF4246 PF14033.6 KND92733.1 - 1.2e-169 565.2 0.0 1.5e-169 564.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KND92733.1 - 0.032 14.7 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Pkinase PF00069.25 KND92734.1 - 6.3e-17 61.8 0.0 1.1e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND92734.1 - 0.00035 19.9 0.0 0.13 11.5 0.0 2.8 2 2 0 2 2 2 2 Protein tyrosine kinase WaaY PF06176.11 KND92734.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) eIF-3c_N PF05470.12 KND92735.1 - 6.2e-177 589.5 23.4 6.2e-177 589.5 23.4 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KND92735.1 - 3.4e-13 50.0 0.0 1.9e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain DUF2779 PF11074.8 KND92735.1 - 0.058 13.9 2.4 1.5 9.3 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function(DUF2779) Streptin-Immun PF11083.8 KND92735.1 - 0.23 11.9 4.1 0.57 10.6 0.3 3.3 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Tannase PF07519.11 KND92736.1 - 3.5e-99 332.8 0.0 4.1e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KND92736.1 - 0.0061 16.1 0.2 1.3 8.5 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND92736.1 - 0.016 14.5 0.0 0.058 12.7 0.1 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Fe-S_biosyn PF01521.20 KND92738.1 - 3.9e-12 46.3 0.0 9.9e-11 41.8 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 KND92739.1 - 7.4e-23 80.6 16.5 1.3e-22 79.8 16.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KND92739.1 - 3.4e-18 65.3 2.1 9.4e-18 63.8 2.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Synuclein PF01387.17 KND92739.1 - 0.16 12.2 2.4 0.33 11.2 1.9 1.7 1 1 1 2 2 2 0 Synuclein SNF2_N PF00176.23 KND92741.1 - 4.1e-67 226.4 1.8 1.9e-66 224.2 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND92741.1 - 4.1e-15 56.1 0.0 1.2e-14 54.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND92741.1 - 3.6e-08 33.6 0.0 9.6e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2935 PF11155.8 KND92741.1 - 0.085 13.2 4.5 0.11 12.8 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) LPP PF04728.13 KND92741.1 - 8.5 6.9 8.3 2.1 8.8 0.9 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper APH PF01636.23 KND92743.1 - 0.0058 16.6 0.2 0.0088 16.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Metallophos PF00149.28 KND92745.1 - 5.9e-18 66.1 0.1 9.6e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KND92745.1 - 1.7e-17 64.0 0.1 4.9e-17 62.5 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KND92745.1 - 7.8e-14 52.0 0.6 2e-13 50.7 0.6 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KND92745.1 - 0.011 16.2 0.0 0.034 14.7 0.0 1.8 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain p450 PF00067.22 KND92746.1 - 7e-55 186.6 0.0 8.7e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alkyl_sulf_C PF14864.6 KND92746.1 - 0.049 13.9 0.1 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal E1-E2_ATPase PF00122.20 KND92747.1 - 8.5e-51 172.0 8.8 7.1e-50 169.0 3.7 2.8 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 KND92747.1 - 1.8e-26 93.8 7.4 1.8e-26 93.8 7.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KND92747.1 - 1.7e-12 47.6 0.1 1.7e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 Heavy-metal-associated domain HyaE PF07449.11 KND92747.1 - 0.047 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE HAD PF12710.7 KND92747.1 - 0.3 11.5 1.7 0.81 10.1 1.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 KND92748.1 - 2.6e-09 37.1 7.0 2.2e-08 34.1 7.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KND92749.1 - 0.058 13.4 4.7 0.073 13.1 4.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hyd_65N_2 PF14498.6 KND92750.1 - 1.2e-09 38.4 0.1 1.4e-08 34.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain dCMP_cyt_deam_1 PF00383.23 KND92751.1 - 2.4e-20 72.3 0.0 7e-20 70.8 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KND92751.1 - 7.7e-16 58.1 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KND92751.1 - 0.03 14.4 0.1 0.03 14.4 0.1 3.4 3 1 1 4 4 4 0 Bd3614-like deaminase Inv-AAD PF18785.1 KND92751.1 - 0.074 12.9 0.0 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase Zn_clus PF00172.18 KND92752.1 - 0.069 13.3 9.1 0.17 12.0 9.1 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_topoisoIV PF00521.20 KND92753.1 - 6.2e-121 404.3 0.0 1.1e-120 403.4 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KND92753.1 - 1.2e-47 161.4 2.4 3.5e-47 159.9 2.4 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KND92753.1 - 3.3e-24 85.3 0.3 6.5e-24 84.3 0.3 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KND92753.1 - 2.7e-12 47.2 0.1 7e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KND92753.1 - 2.9e-06 27.4 0.0 9.4e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Ank_4 PF13637.6 KND92754.1 - 4.8e-26 90.8 0.8 2.1e-09 37.7 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND92754.1 - 5.9e-25 87.7 0.5 1.3e-13 51.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND92754.1 - 9.4e-19 65.5 0.7 0.00086 19.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KND92754.1 - 4.3e-17 61.7 3.0 0.00021 21.6 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KND92754.1 - 7.8e-16 57.9 1.5 2.4e-08 34.1 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (many copies) F-box-like PF12937.7 KND92754.1 - 0.00038 20.3 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like Amidase PF01425.21 KND92754.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Amidase LEA_6 PF10714.9 KND92755.1 - 0.022 14.8 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 dsDNA_bind PF01984.20 KND92756.1 - 5.5e-39 132.9 10.9 1.4e-38 131.6 10.9 1.7 1 0 0 1 1 1 1 Double-stranded DNA-binding domain ApbA_C PF08546.11 KND92756.1 - 9.8e-14 51.6 0.0 2.2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KND92756.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Coq4 PF05019.13 KND92757.1 - 2.3e-90 301.8 0.0 1.1e-83 280.0 0.0 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 FAD_binding_3 PF01494.19 KND92758.1 - 3e-11 43.2 0.1 1.1e-09 38.1 0.0 2.8 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 KND92758.1 - 0.0037 16.9 0.1 0.008 15.8 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND92758.1 - 0.0048 16.9 2.5 0.86 9.6 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KND92758.1 - 0.007 16.6 0.4 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KND92758.1 - 0.013 14.6 0.4 0.87 8.6 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Rick_17kDa_Anti PF05433.15 KND92760.1 - 0.0015 18.3 10.0 0.023 14.5 0.1 2.6 2 1 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KND92760.1 - 0.13 12.3 8.7 1.8 8.6 1.3 2.3 2 0 0 2 2 2 0 Glycine zipper Peptidase_C48 PF02902.19 KND92761.1 - 1.8e-19 70.4 0.0 3.4e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Borrelia_P83 PF05262.11 KND92761.1 - 0.13 10.7 5.3 0.19 10.1 5.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3987 PF13148.6 KND92761.1 - 1.5 7.7 10.9 2.6 7.0 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FAD_binding_3 PF01494.19 KND92763.1 - 2.6e-70 237.4 0.0 3.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KND92763.1 - 2.1e-36 125.5 0.0 3.4e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 KND92763.1 - 0.13 12.5 0.0 0.48 10.7 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.32 KND92765.1 - 0.0012 19.7 2.8 0.14 13.1 0.0 4.0 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92765.1 - 0.0012 19.1 0.0 0.44 10.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain LCM PF04072.14 KND92766.1 - 2.7e-18 66.6 0.0 3.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DAO PF01266.24 KND92767.1 - 4.3e-53 181.1 0.0 5.9e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KND92767.1 - 1.6e-44 150.8 0.0 2.8e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KND92767.1 - 1.4e-08 34.3 1.5 5.5e-08 32.3 1.5 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KND92767.1 - 4e-06 26.4 0.0 0.00074 19.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KND92767.1 - 0.00027 20.3 0.6 0.14 11.4 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND92767.1 - 0.00086 19.5 0.4 0.0028 17.8 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND92767.1 - 0.0012 18.1 0.2 0.0032 16.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND92767.1 - 0.0018 18.8 0.9 0.062 13.9 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND92767.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND92767.1 - 0.0022 17.3 1.9 0.057 12.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KND92767.1 - 0.0058 15.4 0.3 0.0098 14.6 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KND92767.1 - 0.022 13.8 0.2 0.13 11.3 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KND92767.1 - 0.086 12.7 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RGS PF00615.19 KND92768.1 - 4.8e-07 30.1 0.0 8.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain HNH_2 PF13391.6 KND92769.1 - 2.1e-09 37.3 0.0 5.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease PIEZO PF15917.5 KND92769.1 - 0.16 11.4 0.9 0.28 10.6 0.9 1.3 1 0 0 1 1 1 0 Piezo Med7 PF05983.11 KND92770.1 - 1.7e-60 204.4 0.0 1.9e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 MED7 protein TBCC_N PF16752.5 KND92770.1 - 0.13 12.7 0.2 0.54 10.7 0.2 1.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain zf-C2H2_jaz PF12171.8 KND92772.1 - 0.12 12.7 0.4 0.2 12.0 0.4 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FAM76 PF16046.5 KND92772.1 - 0.85 8.9 3.7 2.3 7.5 0.9 2.1 2 0 0 2 2 2 0 FAM76 protein PAP2 PF01569.21 KND92773.1 - 1.2e-26 93.1 0.2 1.2e-26 93.1 0.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 KND92773.1 - 1.8e-05 24.5 3.6 0.00041 20.1 0.1 2.6 3 0 0 3 3 3 2 PAP2 superfamily Proteasome PF00227.26 KND92774.1 - 1.3e-44 152.0 0.0 1.5e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KND92775.1 - 1.7e-13 50.0 0.1 1.7e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Proteasome PF00227.26 KND92775.1 - 1.5e-08 34.3 0.1 2.1e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Nitrate_red_gam PF02665.14 KND92775.1 - 0.2 11.2 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit RPEL PF02755.15 KND92776.1 - 0.00091 18.9 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 RPEL repeat Uma2 PF05685.12 KND92777.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Putative restriction endonuclease DUF2913 PF11140.8 KND92777.1 - 0.14 11.9 0.1 0.18 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) zf-CCHC_2 PF13696.6 KND92777.1 - 0.21 11.4 3.8 3.2 7.6 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-NADH-PPase PF09297.11 KND92778.1 - 0.015 14.9 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KND92778.1 - 0.027 14.2 0.3 0.05 13.3 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain GFA PF04828.14 KND92778.1 - 0.028 14.8 0.0 0.031 14.6 0.0 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.10 KND92778.1 - 0.043 13.5 0.5 0.065 13.0 0.5 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Cys_rich_KTR PF14205.6 KND92778.1 - 0.11 12.3 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Cysteine-rich KTR MgsA_C PF12002.8 KND92780.1 - 3e-61 206.2 0.0 5.9e-61 205.3 0.0 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KND92780.1 - 8e-23 80.6 0.1 1.6e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KND92780.1 - 4.8e-13 49.7 0.1 8.7e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND92780.1 - 7.3e-09 35.6 0.0 1.5e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND92780.1 - 1.4e-05 25.5 0.3 0.036 14.4 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KND92780.1 - 4.2e-05 23.3 0.0 0.091 12.5 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.6 KND92780.1 - 4.3e-05 23.4 0.0 0.002 17.9 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KND92780.1 - 4.6e-05 22.9 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND92780.1 - 0.00043 20.3 0.1 0.0067 16.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KND92780.1 - 0.002 18.1 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KND92780.1 - 0.005 16.9 0.1 0.93 9.5 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 KND92780.1 - 0.0056 15.9 0.0 0.0082 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain SKI PF01202.22 KND92780.1 - 0.0077 16.4 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase DUF815 PF05673.13 KND92780.1 - 0.0097 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KND92780.1 - 0.015 15.2 0.0 0.073 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND92780.1 - 0.024 14.9 0.6 1.2 9.4 0.4 2.5 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.6 KND92780.1 - 0.041 14.4 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KND92780.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) zf_UBZ PF18439.1 KND92780.1 - 0.06 13.0 0.3 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger AAA_33 PF13671.6 KND92780.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain TRAF6_Z2 PF18048.1 KND92780.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 Herpes_BLLF1 PF05109.13 KND92780.1 - 0.12 10.4 1.4 0.16 9.9 1.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-WRNIP1_ubi PF18279.1 KND92780.1 - 0.38 11.5 1.6 0.51 11.1 0.1 2.0 2 0 0 2 2 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain tRNA-synt_2b PF00587.25 KND92781.1 - 3.4e-20 72.8 0.0 5.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KND92781.1 - 8.7e-10 38.8 0.6 1.6e-09 37.9 0.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 KND92782.1 - 1.1e-74 251.1 0.0 1.6e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92782.1 - 1.6e-30 106.3 0.0 7.3e-22 77.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KND92782.1 - 1.1e-05 25.0 0.1 1.4 8.2 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KND92782.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KND92782.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thump_like PF18096.1 KND92782.1 - 0.029 14.3 0.0 0.099 12.6 0.0 1.9 1 0 0 1 1 1 0 THUMP domain-like APH PF01636.23 KND92782.1 - 0.042 13.8 0.0 0.83 9.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND92782.1 - 0.18 10.7 0.1 0.71 8.8 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain C2 PF00168.30 KND92783.1 - 3e-25 88.5 0.0 1e-14 54.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain Amidohydro_1 PF01979.20 KND92784.1 - 2.2e-13 50.3 0.0 3.9e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KND92784.1 - 1.7e-05 24.5 0.1 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family AA_permease PF00324.21 KND92785.1 - 3e-30 105.2 29.3 1.1e-18 67.2 10.5 2.9 2 1 0 2 2 2 2 Amino acid permease APH PF01636.23 KND92787.1 - 3.9e-05 23.7 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PALP PF00291.25 KND92789.1 - 2e-53 181.7 2.3 2.9e-53 181.2 2.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_Phos_1 PF00300.22 KND92789.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Alpha-amylase PF00128.24 KND92790.1 - 1.4e-51 176.1 0.0 3.6e-50 171.4 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KND92790.1 - 0.037 12.2 1.1 0.84 7.7 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 70 DUF1966 PF09260.11 KND92790.1 - 0.063 13.6 0.1 0.15 12.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1966) NOA36 PF06524.12 KND92792.1 - 5 6.3 10.9 8.7 5.6 10.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4646 PF15496.6 KND92793.1 - 0.055 14.1 0.0 0.087 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) AbiEii PF08843.11 KND92794.1 - 0.0054 16.7 0.2 0.018 15.0 0.2 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system CysG_dimeriser PF10414.9 KND92794.1 - 0.032 13.9 3.2 0.71 9.6 0.1 2.4 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Lung_7-TM_R PF06814.13 KND92795.1 - 9.9e-72 241.7 15.8 1.2e-71 241.4 15.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 KND92795.1 - 2.6 7.8 5.2 4.6 7.0 0.1 3.2 3 1 1 4 4 4 0 SurA N-terminal domain Pro_isomerase PF00160.21 KND92796.1 - 1e-48 165.6 0.0 1.9e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KND92796.1 - 0.00068 19.8 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 KND92796.1 - 0.0042 17.2 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Pkinase PF00069.25 KND92797.1 - 1.1e-44 152.8 0.0 1.4e-44 152.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92797.1 - 6e-17 61.8 0.0 9.4e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND92797.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND92797.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND92797.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_28 PF02636.17 KND92798.1 - 3.5e-81 272.7 0.0 4.3e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Glyco_hydro_16 PF00722.21 KND92800.1 - 4.7e-12 45.7 0.1 6.8e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KND92801.1 - 6.7e-08 31.9 3.8 3.9e-05 22.8 1.1 2.6 2 1 1 3 3 3 2 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KND92801.1 - 0.0014 18.9 9.0 0.087 13.3 1.1 3.0 1 1 1 2 2 2 2 Zinc-finger double domain TackOD1 PF18551.1 KND92801.1 - 0.011 15.4 0.7 0.011 15.4 0.7 1.7 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-C2H2_4 PF13894.6 KND92801.1 - 0.023 15.5 8.3 0.73 10.8 1.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KND92801.1 - 0.099 13.1 9.8 0.94 10.1 1.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 KND92801.1 - 0.11 13.1 0.5 7.2 7.3 0.0 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Fungal_trans_2 PF11951.8 KND92802.1 - 4e-09 35.8 0.1 2.1e-07 30.1 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92802.1 - 1.6e-07 31.3 11.9 3e-07 30.4 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_64 PF16483.5 KND92803.1 - 2.1e-131 438.6 0.0 2.4e-131 438.4 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase CDC45 PF02724.14 KND92804.1 - 0.8 7.9 7.0 1.1 7.4 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KND92804.1 - 1.7 7.9 9.4 2.4 7.4 9.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KND92804.1 - 2.2 6.4 12.9 2.9 6.0 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family RasGEF PF00617.19 KND92806.1 - 2.6e-59 200.4 0.1 5e-59 199.5 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KND92806.1 - 7.4e-29 100.1 0.2 1.9e-28 98.8 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KND92806.1 - 1.7e-15 56.3 0.1 3.5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KND92806.1 - 3.6e-14 52.3 0.2 8.1e-14 51.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KND92806.1 - 2e-13 49.8 0.1 5.3e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KND92806.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 WW domain PPR_2 PF13041.6 KND92809.1 - 1e-21 76.8 0.0 8.7e-15 54.7 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KND92809.1 - 9.8e-11 41.6 0.1 0.00097 19.2 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 KND92809.1 - 2e-07 30.6 0.1 4.2e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KND92809.1 - 9.5e-06 25.5 0.8 0.96 9.8 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 KND92809.1 - 0.00011 21.8 0.1 6.1 6.6 0.0 4.5 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.7 KND92809.1 - 0.032 14.1 0.2 0.59 10.0 0.0 2.8 2 1 2 4 4 4 0 Mitochondrial ATPase expression Btz PF09405.10 KND92810.1 - 0.0053 17.0 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Pkinase PF00069.25 KND92811.1 - 1e-49 169.3 0.2 3.9e-49 167.4 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92811.1 - 6.3e-24 84.7 0.0 1.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND92811.1 - 0.00025 21.0 1.5 0.00034 20.6 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KND92811.1 - 0.003 17.2 0.2 0.0078 15.8 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KND92811.1 - 0.52 9.9 2.5 0.42 10.1 0.2 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aquarius_N PF16399.5 KND92812.1 - 0 1082.0 0.0 0 1081.7 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KND92812.1 - 8.2e-28 97.4 0.0 1.5e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KND92812.1 - 9e-21 74.8 0.0 7.3e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND92812.1 - 2.1e-07 30.9 0.0 0.00071 19.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KND92812.1 - 6.1e-06 26.3 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KND92812.1 - 3.1e-05 24.3 0.0 6.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND92812.1 - 0.0017 18.8 2.7 0.0033 17.8 0.0 2.8 4 0 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 KND92812.1 - 0.0041 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KND92812.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 KND92812.1 - 0.032 14.5 0.4 0.19 12.0 0.1 2.5 2 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 KND92812.1 - 0.054 13.2 0.1 5.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KND92812.1 - 0.072 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 KND92812.1 - 0.073 12.2 0.0 9.8 5.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 KND92812.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KND92812.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RecA PF00154.21 KND92812.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NACHT PF05729.12 KND92812.1 - 0.88 9.5 3.1 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain MIF4G PF02854.19 KND92813.1 - 1.1e-51 175.5 0.0 1.8e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KND92813.1 - 5.6e-21 74.5 0.6 2.3e-20 72.5 0.6 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 HSP70 PF00012.20 KND92813.1 - 3.2 5.8 19.3 6.4 4.8 19.3 1.4 1 0 0 1 1 1 0 Hsp70 protein FUSC PF04632.12 KND92813.1 - 7.5 4.9 5.1 16 3.9 5.1 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family DNA_pol_B PF00136.21 KND92814.1 - 2.3e-114 382.7 0.1 4.6e-114 381.7 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KND92814.1 - 1.7e-65 220.2 0.2 3e-65 219.4 0.2 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KND92814.1 - 8.4e-41 140.2 0.0 1.9e-40 139.0 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KND92814.1 - 1.8e-24 85.5 9.2 1.8e-24 85.5 9.2 2.9 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KND92814.1 - 0.0048 15.8 0.0 0.027 13.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Med2 PF11214.8 KND92816.1 - 0.051 13.7 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Cellulase PF00150.18 KND92817.1 - 6.8e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S10 PF00338.22 KND92818.1 - 6.4e-25 87.3 0.0 1e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3984 PF13136.6 KND92819.1 - 1e-62 212.5 21.5 1.5e-61 208.7 21.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) Lipase_GDSL_2 PF13472.6 KND92820.1 - 4.4e-17 63.0 0.3 6.5e-17 62.5 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND92820.1 - 9.9e-08 32.2 0.0 1.8e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AIP3 PF03915.13 KND92821.1 - 6.3e-156 519.6 6.8 9.6e-156 519.0 6.8 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1664 PF07889.12 KND92821.1 - 0.0012 18.9 3.5 1.4 9.0 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KND92821.1 - 0.088 13.3 6.2 1.5 9.4 0.1 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MIP-T3_C PF17749.1 KND92821.1 - 0.11 12.5 3.5 0.33 10.9 0.9 3.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DivIC PF04977.15 KND92821.1 - 0.33 10.7 2.5 10 6.0 0.4 3.6 3 0 0 3 3 3 0 Septum formation initiator FliL PF03748.14 KND92821.1 - 0.48 11.0 0.1 0.48 11.0 0.1 2.8 3 1 0 3 3 3 0 Flagellar basal body-associated protein FliL CK2S PF15011.6 KND92821.1 - 2.6 7.9 9.5 0.44 10.4 0.3 3.6 4 1 0 4 4 4 0 Casein Kinase 2 substrate COG2 PF06148.11 KND92821.1 - 3 7.9 8.7 7.5 6.6 0.2 4.2 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.6 KND92821.1 - 4.1 7.8 6.8 18 5.8 0.0 4.4 4 1 1 5 5 5 0 Syntaxin-like protein CorA PF01544.18 KND92821.1 - 4.7 6.4 5.3 2.8 7.2 0.6 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein IKI3 PF04762.12 KND92822.1 - 1.4e-295 983.1 0.0 1.7e-295 982.8 0.0 1.0 1 0 0 1 1 1 1 IKI3 family TPR_7 PF13176.6 KND92822.1 - 5.4 7.3 6.2 6.4 7.0 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EPSP_synthase PF00275.20 KND92823.1 - 2.1e-130 435.2 0.0 4.1e-130 434.2 0.0 1.5 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KND92823.1 - 4.6e-102 340.7 0.0 9.3e-102 339.7 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KND92823.1 - 7.6e-55 186.7 0.0 1.8e-54 185.4 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase RasGAP PF00616.19 KND92823.1 - 3.8e-32 111.7 0.2 4.1e-29 101.8 0.2 2.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase SKI PF01202.22 KND92823.1 - 7.8e-32 110.6 0.0 1.7e-30 106.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KND92823.1 - 1.2e-24 86.3 0.0 3.5e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KND92823.1 - 8.4e-06 25.7 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KND92823.1 - 9.9e-06 25.7 0.0 3.1e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CRAL_TRIO_2 PF13716.6 KND92823.1 - 2.7e-05 24.3 0.0 8.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SDH_C PF18317.1 KND92823.1 - 0.0007 19.3 0.0 0.0029 17.3 0.0 2.2 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KND92823.1 - 0.11 12.8 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 KND92823.1 - 0.12 12.5 0.0 0.41 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 KND92824.1 - 4.4e-07 30.0 24.1 0.0046 17.3 1.9 4.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type Eapp_C PF10238.9 KND92824.1 - 0.3 11.1 9.0 0.083 13.0 5.3 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein zf-C2H2_4 PF13894.6 KND92824.1 - 2.6 9.1 27.1 1.1 10.3 1.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger ARD PF03079.14 KND92825.1 - 4.3e-43 147.2 0.0 5.3e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KND92825.1 - 1e-07 31.5 0.2 1.7e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KND92825.1 - 1.4e-05 25.0 0.1 2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short PF00106.25 KND92826.1 - 3.5e-27 95.1 0.0 4.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND92826.1 - 3.7e-19 69.2 0.0 5.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND92826.1 - 2e-09 37.6 0.0 3.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND92826.1 - 4e-05 23.2 0.0 7.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND92826.1 - 0.0043 16.2 0.0 0.0094 15.1 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KND92826.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KND92826.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DER1 PF04511.15 KND92827.1 - 4.8e-50 170.2 6.6 5.6e-50 169.9 6.6 1.0 1 0 0 1 1 1 1 Der1-like family PHO4 PF01384.20 KND92828.1 - 4.4e-99 331.7 20.1 5.4e-99 331.4 20.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 KND92828.1 - 0.73 10.1 6.1 1.9 8.8 0.3 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DUF1290 PF06947.12 KND92829.1 - 0.21 11.7 2.1 0.53 10.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) SPC12 PF06645.13 KND92829.1 - 0.4 10.8 2.3 1.1 9.4 1.3 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FUN14 PF04930.15 KND92829.1 - 0.78 10.2 5.2 0.92 10.0 3.4 1.9 2 0 0 2 2 2 0 FUN14 family tRNA-synt_1b PF00579.25 KND92831.1 - 6.1e-73 245.7 0.0 7.5e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Creatinase_N_2 PF16189.5 KND92832.1 - 9e-49 165.7 0.0 2e-48 164.5 0.0 1.6 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KND92832.1 - 2.8e-44 151.3 0.0 4.2e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KND92832.1 - 1.7e-19 69.7 0.1 4.5e-19 68.3 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KND92832.1 - 1.5e-16 61.3 0.0 7.3e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain PAD_porph PF04371.15 KND92833.1 - 9.9e-99 330.6 0.0 1.1e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 KND92833.1 - 0.042 12.9 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Amidinotransferase Fungal_trans PF04082.18 KND92834.1 - 6.2e-13 48.4 0.3 9.9e-13 47.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fer4_9 PF13187.6 KND92834.1 - 0.13 12.5 0.6 0.35 11.1 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Abhydrolase_2 PF02230.16 KND92835.1 - 2.7e-24 86.2 0.0 9.1e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 KND92835.1 - 0.002 17.7 0.1 0.0047 16.5 0.0 1.6 1 1 1 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KND92835.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND92835.1 - 0.054 12.8 0.1 0.12 11.7 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 MCRA PF06100.11 KND92836.1 - 4.5e-220 731.6 0.0 5.4e-220 731.4 0.0 1.1 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 KND92836.1 - 9.7e-07 28.9 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND92836.1 - 0.0012 18.5 0.2 0.19 11.3 0.2 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND92836.1 - 0.0077 16.8 0.1 1.7 9.3 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND92836.1 - 0.01 15.1 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND92836.1 - 0.041 13.0 0.3 0.17 10.9 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 KND92836.1 - 0.099 11.9 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Ish1 PF10281.9 KND92836.1 - 0.12 12.7 0.0 3.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein FAD_binding_7 PF03441.14 KND92837.1 - 3.3e-46 157.3 0.4 5.1e-46 156.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KND92837.1 - 1.1e-19 71.1 0.0 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Cu_bind_like PF02298.17 KND92838.1 - 0.0028 17.6 0.2 0.007 16.4 0.2 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.6 KND92838.1 - 0.0033 17.5 0.0 0.0081 16.3 0.0 1.6 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 KND92838.1 - 0.018 15.4 0.5 0.13 12.7 0.5 2.2 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cu-oxidase_2 PF07731.14 KND92838.1 - 0.037 13.8 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Multicopper oxidase DUF2076 PF09849.9 KND92838.1 - 0.91 9.5 5.3 1.2 9.1 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MmgE_PrpD PF03972.14 KND92839.1 - 7.8e-142 472.9 0.0 8.8e-142 472.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Glyco_hydro_79C PF16862.5 KND92840.1 - 2e-14 54.3 0.1 5.8e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RIBIOP_C PF04950.12 KND92841.1 - 8.5e-109 363.5 0.0 1.5e-108 362.6 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KND92841.1 - 5.3e-16 58.5 0.0 1.4e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Asp PF00026.23 KND92842.1 - 1.7e-71 241.3 5.6 2.2e-71 240.9 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND92842.1 - 1.5e-11 44.8 8.4 5.3e-10 39.8 5.2 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 KND92842.1 - 0.00052 20.5 0.0 0.0061 17.1 0.0 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KND92842.1 - 0.0019 18.8 1.3 0.034 14.8 0.0 3.1 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 KND92842.1 - 0.0071 16.1 0.0 0.036 13.8 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal CLU PF13236.6 KND92843.1 - 4.1e-75 252.4 0.0 6.6e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 KND92843.1 - 9e-56 188.7 0.0 2.1e-55 187.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KND92843.1 - 1.6e-23 82.8 5.1 6.3e-11 42.4 0.1 4.1 2 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 KND92843.1 - 5.8e-22 77.8 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 KND92843.1 - 3.6e-19 68.0 0.7 8.6e-06 25.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND92843.1 - 0.00033 20.6 3.9 0.005 17.0 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND92843.1 - 0.00053 19.9 1.8 0.056 13.6 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 KND92843.1 - 0.032 14.3 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_17 PF13431.6 KND92843.1 - 0.2 12.1 2.6 34 5.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Nuc_sug_transp PF04142.15 KND92845.1 - 8.7e-09 35.0 0.3 1.6e-08 34.1 0.2 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KND92845.1 - 2.3e-08 34.3 27.3 4.8e-05 23.5 3.9 2.7 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 KND92845.1 - 0.0003 20.2 0.8 0.0003 20.2 0.8 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family WBS28 PF15164.6 KND92845.1 - 0.11 11.7 2.6 0.2 10.9 2.6 1.5 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF2985 PF11204.8 KND92846.1 - 3.4e-40 136.1 1.4 3.4e-40 136.1 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 KND92846.1 - 0.029 14.4 3.3 0.037 14.1 0.1 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ADH_N PF08240.12 KND92847.1 - 1.9e-30 105.0 1.6 1.9e-30 105.0 1.6 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND92847.1 - 1.9e-15 57.0 0.0 2.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND92847.1 - 6.7e-07 29.0 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KND92847.1 - 8.8e-05 21.9 0.2 0.00012 21.4 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KND92847.1 - 0.00051 21.1 0.0 0.00085 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KND92847.1 - 0.033 14.1 0.1 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated AP_endonuc_2 PF01261.24 KND92847.1 - 0.041 13.3 0.0 6.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel TrkA_N PF02254.18 KND92847.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sen15 PF09631.10 KND92848.1 - 5.1e-28 97.3 0.0 6.3e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Peptidase_C2 PF00648.21 KND92850.1 - 9.6e-23 80.6 0.0 1.5e-21 76.8 0.0 2.0 1 1 1 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 KND92850.1 - 6.9e-08 32.9 0.1 9.3e-06 25.9 0.0 3.1 2 2 0 2 2 2 1 Calpain large subunit, domain III zf-C2H2 PF00096.26 KND92852.1 - 0.00063 20.1 6.8 0.73 10.4 0.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND92852.1 - 0.066 13.7 2.5 7.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain GHMP_kinases_N PF00288.26 KND92853.1 - 5.4e-16 58.6 0.1 1.4e-15 57.3 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND92853.1 - 5.5e-10 39.5 0.0 1.9e-09 37.7 0.0 1.9 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KND92853.1 - 0.0058 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature XPC-binding PF09280.11 KND92853.1 - 0.14 11.9 0.1 6.2 6.6 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain RCDG1 PF15725.5 KND92853.1 - 0.44 11.0 2.0 2.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein 2OG-FeII_Oxy_3 PF13640.6 KND92854.1 - 2.1e-09 38.1 0.0 4.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PNP_UDP_1 PF01048.20 KND92855.1 - 1.2e-10 41.0 0.0 1.3e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 KND92855.1 - 0.014 14.6 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) cobW PF02492.19 KND92856.1 - 4.1e-31 107.9 0.0 6.8e-31 107.2 0.0 1.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KND92856.1 - 5.9e-05 22.2 0.0 0.039 12.9 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 KND92856.1 - 0.0042 17.6 0.0 0.0065 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KND92856.1 - 0.031 14.4 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KND92856.1 - 0.079 13.3 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cnn_1N PF07989.11 KND92857.1 - 9.2 6.5 8.4 8.2 6.7 2.2 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 BING4CT PF08149.11 KND92858.1 - 2.4e-40 136.2 0.1 1.6e-36 123.9 0.0 3.8 4 0 0 4 4 4 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 KND92858.1 - 1.4e-07 31.7 2.6 2.2 8.6 0.0 6.0 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND92858.1 - 2.4e-06 28.1 0.0 0.46 11.4 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 KND92858.1 - 4.5e-06 26.0 0.1 0.00067 18.8 0.0 2.2 2 0 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 KND92858.1 - 0.053 12.0 0.0 7.7 4.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ras PF00071.22 KND92859.1 - 1.1e-55 187.7 0.0 1.2e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND92859.1 - 7.7e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92859.1 - 3.5e-07 29.9 0.0 5.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KND92859.1 - 0.0026 17.2 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Skp1 PF01466.19 KND92859.1 - 0.012 15.7 0.6 0.069 13.3 0.1 2.3 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Gtr1_RagA PF04670.12 KND92859.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Aa_trans PF01490.18 KND92860.1 - 6.9e-68 229.2 30.6 8.3e-68 229.0 30.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.6 KND92860.1 - 0.0078 16.0 4.4 0.0078 16.0 4.4 2.8 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction PPTA PF01239.22 KND92861.1 - 0.00015 21.4 11.2 0.019 14.7 0.6 4.2 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat MIEAP PF16026.5 KND92862.1 - 0.0043 17.3 0.1 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Mitochondria-eating protein Lebercilin PF15619.6 KND92862.1 - 0.0049 16.6 10.8 0.29 10.8 1.9 2.6 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease HrpB7 PF09486.10 KND92862.1 - 0.0056 17.1 7.0 0.013 15.9 7.0 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 KND92862.1 - 0.021 15.0 5.2 0.021 15.0 5.2 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 KND92862.1 - 0.033 13.1 6.8 0.053 12.4 6.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 KND92862.1 - 0.057 13.5 6.3 0.11 12.6 6.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UPF0242 PF06785.11 KND92862.1 - 0.099 12.7 6.9 0.24 11.5 6.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 KND92862.1 - 0.13 12.2 3.9 2.4 8.2 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 KND92862.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 KND92862.1 - 0.16 11.4 11.3 0.25 10.8 11.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 KND92862.1 - 0.89 9.8 11.2 1 9.6 3.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3824 PF12868.7 KND92862.1 - 1.6 9.4 7.4 3.7 8.2 7.4 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PKcGMP_CC PF16808.5 KND92862.1 - 1.8 8.5 16.8 0.93 9.4 1.4 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM184 PF15665.5 KND92862.1 - 3.6 7.3 13.5 1.1 9.0 9.9 1.8 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B AKAP7_NLS PF10469.9 KND92863.1 - 1.1e-26 94.0 0.0 1.3e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 KND92863.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Ras PF00071.22 KND92864.1 - 3.9e-52 176.1 0.0 4.7e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND92864.1 - 5.6e-19 68.5 0.0 7.5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92864.1 - 7.8e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.21 KND92865.1 - 5.1e-87 291.9 0.0 1.2e-85 287.4 0.0 2.5 2 0 0 2 2 2 1 Arginase family tRNA-synt_2 PF00152.20 KND92865.1 - 2.8e-78 263.2 0.8 8.3e-71 238.6 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KND92865.1 - 7.8e-08 32.2 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KND92865.1 - 0.0096 16.1 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain UPF0489 PF12640.7 KND92865.1 - 0.054 13.7 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 UPF0489 domain MFS_1 PF07690.16 KND92866.1 - 5.7e-47 160.3 32.7 1.9e-39 135.6 18.3 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND92866.1 - 6.9e-11 41.3 16.0 1.6e-06 27.0 4.0 3.0 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 KND92866.1 - 6.8e-07 28.0 13.0 0.00079 17.9 5.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.24 KND92866.1 - 4.8e-05 22.4 14.7 0.0023 16.9 1.1 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 KND92866.1 - 0.00017 20.1 1.3 0.0039 15.6 1.0 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 KND92866.1 - 0.0027 16.4 2.5 0.52 8.9 0.1 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 KND92866.1 - 1.3 7.8 19.7 0.089 11.6 7.0 3.7 2 2 2 4 4 4 0 MFS_1 like family COX7C PF02935.16 KND92866.1 - 3.9 7.8 7.5 1.8 8.8 0.8 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc SURF1 PF02104.15 KND92867.1 - 2.3e-46 158.3 0.1 3.1e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 KND92868.1 - 5.1e-21 74.8 0.1 8e-11 42.0 0.0 3.0 2 1 1 3 3 3 2 Centromere kinetochore component CENP-T histone fold CTU2 PF10288.9 KND92870.1 - 3.9e-10 40.0 0.0 1.2e-07 31.9 0.0 2.9 2 1 1 3 3 3 2 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 KND92870.1 - 0.016 15.0 0.0 0.051 13.3 0.0 2.0 1 1 0 1 1 1 0 PP-loop family DZR PF12773.7 KND92870.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Ras PF00071.22 KND92871.1 - 2e-49 167.3 0.0 1e-33 116.3 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 KND92871.1 - 1.5e-18 67.2 0.0 6.5e-17 61.9 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92871.1 - 8.8e-06 25.3 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family RRM_1 PF00076.22 KND92872.1 - 3e-09 36.5 0.0 8.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Reticulon PF02453.17 KND92873.1 - 9.9e-29 100.3 2.7 9.9e-29 100.3 2.7 2.1 1 1 1 2 2 2 1 Reticulon TAP42 PF04177.12 KND92874.1 - 1.3e-94 316.9 0.0 1.5e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Pkinase PF00069.25 KND92875.1 - 1.1e-13 51.2 0.0 2.9e-08 33.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KND92875.1 - 0.00058 19.3 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND92875.1 - 0.0032 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KND92875.1 - 0.026 13.8 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 KND92875.1 - 0.088 12.1 0.0 1.3 8.3 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Ion_trans PF00520.31 KND92876.1 - 3.8e-07 29.6 29.3 6.5e-07 28.8 29.3 1.3 1 0 0 1 1 1 1 Ion transport protein RabGAP-TBC PF00566.18 KND92877.1 - 1.8e-44 152.0 0.0 3.8e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GAS PF13851.6 KND92877.1 - 0.0095 15.3 2.5 0.0095 15.3 2.5 3.6 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 KND92877.1 - 0.022 14.7 0.7 0.022 14.7 0.7 3.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 KND92877.1 - 1.3 9.0 6.8 0.26 11.3 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 KND92877.1 - 1.3 8.5 3.9 4.5 6.8 3.9 1.9 1 0 0 1 1 1 0 fzo-like conserved region TssO PF17561.2 KND92877.1 - 1.6 8.8 4.2 0.37 10.9 0.4 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF1284 PF06935.11 KND92877.1 - 1.9 9.0 3.9 0.78 10.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Utp12 PF04003.12 KND92877.1 - 3.2 8.1 6.7 1.1 9.6 0.6 3.1 3 0 0 3 3 3 0 Dip2/Utp12 Family SOAR PF16533.5 KND92877.1 - 4.1 7.4 10.7 3 7.9 0.0 3.2 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF641 PF04859.12 KND92877.1 - 6.8 7.0 9.7 0.56 10.6 3.0 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 KND92877.1 - 7.9 6.7 14.2 0.23 11.7 3.4 2.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4574 PF15141.6 KND92877.1 - 9.6 6.2 7.2 23 5.0 1.1 2.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DNA_topoisoIV PF00521.20 KND92878.1 - 6.7e-121 404.1 0.0 2.1e-120 402.5 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KND92878.1 - 2.7e-49 166.7 4.1 8.7e-49 165.1 4.1 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KND92878.1 - 5.1e-25 87.9 0.3 1.1e-24 86.9 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KND92878.1 - 3.3e-12 46.9 0.1 9.9e-12 45.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KND92878.1 - 2.8e-06 27.5 0.0 1.2e-05 25.4 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 KND92878.1 - 0.011 15.6 0.2 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DEAD PF00270.29 KND92880.1 - 4.6e-43 147.0 0.2 6.7e-43 146.5 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND92880.1 - 1.4e-20 73.7 0.4 5.3e-20 71.8 0.2 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KND92880.1 - 0.0043 16.3 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KND92880.1 - 0.0048 16.9 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KND92880.1 - 0.054 13.8 0.1 0.24 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain RIBIOP_C PF04950.12 KND92881.1 - 1.7e-92 310.0 0.1 1.7e-92 310.0 0.1 2.2 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KND92881.1 - 5.2e-27 93.8 0.0 2e-26 91.9 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KND92881.1 - 5.4e-05 23.6 0.0 0.00021 21.7 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 KND92881.1 - 0.00013 22.2 0.0 0.00037 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KND92881.1 - 0.00027 21.5 0.2 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KND92881.1 - 0.00032 20.7 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND92881.1 - 0.00045 19.8 0.0 0.096 12.2 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 KND92881.1 - 0.00091 19.7 0.2 0.0029 18.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KND92881.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 KND92881.1 - 0.0015 18.9 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KND92881.1 - 0.002 18.3 1.1 0.0034 17.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KND92881.1 - 0.0083 16.5 0.1 0.047 14.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KND92881.1 - 0.0099 15.1 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain PduV-EutP PF10662.9 KND92881.1 - 0.011 15.5 0.0 0.046 13.5 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 KND92881.1 - 0.014 14.9 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KND92881.1 - 0.014 15.1 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KND92881.1 - 0.027 14.4 0.1 0.063 13.2 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KND92881.1 - 0.028 14.5 0.3 0.087 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 KND92881.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KND92881.1 - 0.036 14.0 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KND92881.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND92881.1 - 0.046 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 KND92881.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Roc PF08477.13 KND92881.1 - 0.068 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KND92881.1 - 0.097 12.6 0.2 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KND92881.1 - 0.098 12.9 0.0 0.098 12.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 KND92881.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KND92881.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KND92881.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.9 5 0 0 5 5 3 0 AAA domain AAA_23 PF13476.6 KND92881.1 - 2.5 8.6 0.0 2.5 8.6 0.0 4.1 3 1 0 3 3 2 0 AAA domain 2OG-FeII_Oxy_2 PF13532.6 KND92882.1 - 1.2e-33 117.0 0.0 1.6e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KND92882.1 - 8.6e-10 38.6 5.0 1.8e-09 37.5 5.0 1.5 1 0 0 1 1 1 1 GRF zinc finger PfkB PF00294.24 KND92883.1 - 1e-57 195.7 0.2 1.3e-57 195.5 0.2 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CHAT PF12770.7 KND92883.1 - 0.048 13.1 0.9 0.46 9.8 0.2 2.1 1 1 1 2 2 2 0 CHAT domain SUR7 PF06687.12 KND92884.1 - 9.7e-24 84.2 0.0 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KND92884.1 - 0.00023 21.2 2.8 0.00023 21.2 2.8 2.4 3 0 0 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 Ras PF00071.22 KND92885.1 - 1.4e-40 138.5 0.0 8.8e-40 135.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KND92885.1 - 2.7e-31 108.3 0.0 4.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND92885.1 - 4.9e-10 39.1 0.0 8.2e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND92885.1 - 0.00019 21.5 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KND92885.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 KND92885.1 - 0.016 15.6 0.1 0.03 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain RTP1_C2 PF10304.9 KND92885.1 - 0.034 13.8 0.3 0.063 13.0 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 AAA_5 PF07728.14 KND92885.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) P68HR PF08061.11 KND92885.1 - 0.082 13.1 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 P68HR (NUC004) repeat DLIC PF05783.11 KND92885.1 - 0.22 10.3 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) UPF0560 PF10577.9 KND92886.1 - 0.064 11.7 0.0 0.067 11.7 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 HA2 PF04408.23 KND92887.1 - 9.1e-23 80.6 0.0 9.1e-23 80.6 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KND92887.1 - 2.4e-20 72.7 0.0 4.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KND92887.1 - 1.1e-13 51.4 0.0 3.8e-13 49.8 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KND92887.1 - 5.7e-09 36.2 0.1 1.1e-08 35.2 0.1 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 KND92887.1 - 3.4e-05 24.1 0.0 9.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KND92887.1 - 7.9e-05 22.5 1.3 0.00042 20.1 1.3 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KND92887.1 - 0.00016 20.8 0.1 0.00048 19.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KND92887.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KND92887.1 - 0.022 14.2 0.2 0.065 12.7 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KND92887.1 - 0.024 14.7 0.1 0.21 11.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND92887.1 - 0.029 13.6 0.0 0.14 11.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KND92887.1 - 0.063 13.6 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND92887.1 - 0.092 13.3 0.3 0.41 11.1 0.3 2.1 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KND92887.1 - 0.14 11.3 0.1 0.7 9.0 0.1 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Spem1 PF15670.5 KND92887.1 - 0.29 10.7 1.6 0.57 9.7 1.6 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 AAA PF00004.29 KND92888.1 - 2.5e-51 173.5 0.2 3.6e-38 131.0 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND92888.1 - 1.1e-10 41.1 2.2 3e-10 39.7 2.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KND92888.1 - 9.5e-08 32.6 0.0 0.0044 17.4 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KND92888.1 - 4.7e-05 23.4 0.1 0.2 11.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KND92888.1 - 9e-05 22.3 0.0 0.00078 19.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KND92888.1 - 0.00071 19.9 0.0 1.2 9.4 0.0 3.4 2 1 0 3 3 3 1 AAA domain Vps4_C PF09336.10 KND92888.1 - 0.00079 19.4 0.0 0.18 11.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KND92888.1 - 0.0041 16.5 0.9 1.6 8.0 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KND92888.1 - 0.0058 16.2 0.0 12 5.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 KND92888.1 - 0.012 15.9 0.0 0.71 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 KND92888.1 - 0.016 15.0 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KND92888.1 - 0.017 15.5 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.14 KND92888.1 - 0.018 15.2 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KND92888.1 - 0.021 15.0 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KND92888.1 - 0.021 15.2 1.2 0.24 11.7 0.0 3.2 5 0 0 5 5 4 0 AAA domain Rad17 PF03215.15 KND92888.1 - 0.032 14.1 0.0 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 KND92888.1 - 0.091 12.5 0.2 15 5.3 0.0 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 KND92888.1 - 0.1 12.3 0.0 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KND92888.1 - 0.12 12.1 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Glyco_hydro_61 PF03443.14 KND92889.1 - 5e-54 183.4 0.0 7.5e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 KND92890.1 - 3.7e-48 164.2 0.0 1.4e-47 162.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92890.1 - 1.4e-21 76.9 0.0 2.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND92890.1 - 0.0093 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KND92890.1 - 0.046 12.7 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pyr_redox_2 PF07992.14 KND92892.1 - 6.3e-34 117.5 0.1 8.1e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND92892.1 - 0.00027 21.4 1.8 0.0005 20.6 0.7 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND92892.1 - 0.0015 17.7 0.0 0.0039 16.4 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KND92892.1 - 0.0022 17.1 0.4 0.077 12.0 0.2 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KND92892.1 - 0.046 13.7 0.5 4.2 7.3 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 KND92892.1 - 0.11 11.7 5.0 1.3 8.2 0.8 3.1 2 1 1 3 3 3 0 Thi4 family Thioesterase PF00975.20 KND92893.1 - 9.2e-09 35.7 0.0 5.5e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KND92893.1 - 0.0024 18.5 0.3 0.0035 18.0 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KND92893.1 - 0.061 13.2 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KND92893.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TPR_12 PF13424.6 KND92895.1 - 4e-07 30.2 0.3 0.0077 16.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KND92895.1 - 1.4e-05 25.2 2.4 0.014 15.9 0.9 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KND92895.1 - 6e-05 22.8 0.4 0.16 11.8 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND92895.1 - 8.6e-05 23.0 0.5 0.43 11.5 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND92895.1 - 0.00042 20.9 0.4 0.11 13.2 0.8 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND92895.1 - 0.0022 17.9 0.0 3.6 7.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND92895.1 - 0.0078 16.7 0.2 0.1 13.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Cortex-I_coil PF09304.10 KND92895.1 - 0.055 13.7 0.5 0.16 12.2 0.5 1.9 1 0 0 1 1 1 0 Cortexillin I, coiled coil TPR_7 PF13176.6 KND92895.1 - 0.071 13.2 0.9 24 5.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND92895.1 - 0.18 11.7 0.0 9.2 6.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Xan_ur_permease PF00860.20 KND92896.1 - 0.00019 20.3 0.5 0.00024 19.9 0.5 1.1 1 0 0 1 1 1 1 Permease family Glyco_tranf_2_3 PF13641.6 KND92898.1 - 1.8e-09 37.9 0.0 2.5e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HNH_2 PF13391.6 KND92899.1 - 3.4e-13 49.5 0.2 7.6e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease Acetyltransf_10 PF13673.7 KND92900.1 - 3.3e-11 43.2 0.0 1.3e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND92900.1 - 4.9e-08 33.2 0.0 1e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND92900.1 - 1.7e-07 31.6 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND92900.1 - 4.6e-06 26.5 0.0 8.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KND92900.1 - 1.5e-05 25.1 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_tranf_2_3 PF13641.6 KND92901.1 - 3.1e-05 24.0 0.2 3.8e-05 23.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YqjK PF13997.6 KND92902.1 - 0.054 13.7 0.1 4.7 7.5 0.0 2.2 2 0 0 2 2 2 0 YqjK-like protein Ank_2 PF12796.7 KND92903.1 - 3.5e-43 146.1 0.1 1e-17 64.5 0.1 5.0 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 KND92903.1 - 2.7e-40 135.1 0.2 9.8e-06 25.8 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 KND92903.1 - 7.4e-37 125.3 0.6 5.3e-11 42.8 0.0 5.9 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND92903.1 - 1.1e-29 99.1 0.5 0.00024 21.3 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KND92903.1 - 3.5e-29 100.5 0.7 1.2e-10 41.5 0.0 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) HET PF06985.11 KND92903.1 - 2.4e-07 31.2 4.3 5.6e-06 26.8 0.3 2.8 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-C2H2_2 PF12756.7 KND92904.1 - 1.8e-24 86.0 1.3 2.3e-23 82.4 0.5 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KND92904.1 - 0.0011 19.3 0.1 0.0027 18.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND92904.1 - 0.017 15.4 0.5 0.12 12.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4554 PF15091.6 KND92904.1 - 0.073 11.9 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) zf-C2H2_4 PF13894.6 KND92904.1 - 0.076 13.9 3.4 33 5.7 0.1 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_2 PF12796.7 KND92905.1 - 3.9e-59 197.2 17.2 4.5e-14 52.8 0.5 8.2 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND92905.1 - 5.6e-39 132.0 14.9 2e-06 28.2 0.2 10.3 5 3 7 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND92905.1 - 1.1e-35 117.6 18.7 3.8e-05 23.7 0.0 12.1 13 1 0 13 13 13 7 Ankyrin repeat Ank PF00023.30 KND92905.1 - 2.5e-34 116.2 17.1 0.0001 22.6 0.0 12.1 12 1 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 KND92905.1 - 8.3e-27 92.9 14.4 2.5e-05 24.5 0.1 9.2 6 2 3 9 9 9 6 Ankyrin repeats (many copies) ADH_N PF08240.12 KND92906.1 - 1.3e-25 89.4 4.5 2.7e-25 88.4 4.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND92906.1 - 1.1e-15 57.7 0.2 4.1e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase WD40 PF00400.32 KND92906.1 - 1.5e-09 38.3 0.6 0.14 13.1 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND92906.1 - 1.6e-05 25.1 0.0 0.12 12.7 0.0 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain 2-Hacid_dh_C PF02826.19 KND92906.1 - 0.00063 19.2 0.6 0.0011 18.3 0.6 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PD40 PF07676.12 KND92906.1 - 0.055 13.4 0.0 15 5.6 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 KND92907.1 - 1.1e-30 105.2 17.9 1.9e-06 28.5 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KND92907.1 - 6.7e-10 38.7 0.3 1.8e-09 37.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KND92907.1 - 3.3e-06 27.3 0.3 0.14 12.5 0.0 4.8 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KND92907.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KND92907.1 - 0.00041 19.1 2.5 2.8 6.5 0.0 4.0 2 2 2 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KND92907.1 - 0.006 15.2 0.2 0.014 14.0 0.1 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KND92907.1 - 0.085 11.8 0.1 0.55 9.1 0.0 2.2 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallophos PF00149.28 KND92908.1 - 6.5e-10 39.8 0.8 1.3e-09 38.8 0.8 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND92908.1 - 5.1e-09 36.5 0.0 6.8e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_10 PF13374.6 KND92910.1 - 7.7e-25 86.0 0.1 2.5e-10 39.9 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND92910.1 - 8.1e-25 86.9 0.3 7.4e-15 55.0 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND92910.1 - 2.9e-09 36.3 0.2 0.09 12.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KND92910.1 - 0.00038 21.0 0.0 1.4 9.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND92910.1 - 0.0019 18.2 0.0 13 6.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Ntox21 PF15526.6 KND92910.1 - 0.014 15.7 0.2 11 6.3 0.0 2.8 3 0 0 3 3 3 0 Novel toxin 21 TPR_4 PF07721.14 KND92910.1 - 0.048 14.3 0.0 12 6.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND92910.1 - 0.058 13.2 0.0 34 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.7 KND92910.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.7 1 1 1 2 2 2 0 Tetratrico peptide repeat DUF4119 PF13494.6 KND92910.1 - 0.13 12.4 0.6 5.1 7.3 0.2 2.3 1 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Pkinase PF00069.25 KND92911.1 - 7.7e-10 38.6 0.0 1.5e-09 37.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND92911.1 - 2.5e-05 23.7 0.0 3.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND92911.1 - 0.0016 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND92911.1 - 0.0045 16.9 0.5 0.011 15.7 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KND92911.1 - 0.006 16.1 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pectate_lyase_3 PF12708.7 KND92912.1 - 1.8e-94 315.6 28.5 3.2e-85 285.4 11.6 3.6 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KND92912.1 - 6.7e-06 25.7 2.1 0.051 13.3 0.4 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Thiolase_N PF00108.23 KND92914.1 - 1.6e-85 286.6 2.2 2.8e-85 285.8 2.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND92914.1 - 1.4e-38 131.3 1.2 1.4e-38 131.3 1.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KND92914.1 - 4e-05 23.3 0.9 0.00011 21.8 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KND92914.1 - 1.4 8.8 6.7 2.1 8.3 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 KND92915.1 - 6.7e-52 174.9 0.1 9.3e-52 174.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND92915.1 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND92915.1 - 0.016 15.5 0.0 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 RWD domain SUN PF03856.13 KND92916.1 - 3.5e-75 252.6 12.3 4.9e-75 252.1 12.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PCI PF01399.27 KND92917.1 - 0.0091 16.5 0.0 0.086 13.4 0.0 2.1 2 0 0 2 2 2 1 PCI domain LCM PF04072.14 KND92918.1 - 1.2e-21 77.5 0.0 5.2e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 KND92919.1 - 1.5e-28 98.7 2.4 4.2e-28 97.2 0.2 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Kinesin PF00225.23 KND92920.1 - 7.7e-114 380.1 0.4 7.7e-114 380.1 0.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KND92920.1 - 9.2e-27 93.8 0.1 3.3e-26 92.0 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding Peptidase_S49 PF01343.18 KND92920.1 - 1.4 8.9 7.1 0.12 12.3 1.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 ATG16 PF08614.11 KND92920.1 - 6.3 7.0 62.3 0.12 12.6 17.7 3.8 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) ArAE_2_N PF10337.9 KND92922.1 - 2.7e-10 39.9 6.4 7.4e-07 28.6 0.1 3.2 4 0 0 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KND92922.1 - 6.8e-09 35.9 22.3 6.8e-09 35.9 22.3 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KND92922.1 - 3.4e-06 26.2 13.9 2.4e-05 23.4 11.4 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter ArAE_2 PF10334.9 KND92922.1 - 0.00081 19.3 0.1 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 GWT1 PF06423.12 KND92922.1 - 0.19 11.8 0.7 0.66 10.1 0.7 1.9 1 0 0 1 1 1 0 GWT1 Clat_adaptor_s PF01217.20 KND92923.1 - 3.5e-56 189.1 1.8 4e-56 188.9 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CSN8_PSD8_EIF3K PF10075.9 KND92924.1 - 3.2e-38 130.9 0.0 4.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DNA_ligase_A_M PF01068.21 KND92925.1 - 1.8e-49 168.2 0.0 6.4e-47 159.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KND92925.1 - 6.9e-35 120.9 0.0 1.3e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KND92925.1 - 3.6e-19 69.2 0.0 2e-18 66.8 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KND92925.1 - 0.0003 21.2 0.0 0.00055 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase Sugar_tr PF00083.24 KND92926.1 - 4.7e-67 226.8 16.3 6.9e-67 226.3 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND92926.1 - 8.4e-08 31.5 44.5 1.7e-05 24.0 14.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2715 PF10895.8 KND92926.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Glyco_hydro_5_C PF18564.1 KND92927.1 - 2.3e-22 79.3 0.0 7.2e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KND92927.1 - 6.1e-12 45.5 1.6 1.4e-08 34.5 0.5 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KND92927.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KND92927.1 - 0.021 14.2 0.1 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase RMI1_N PF08585.12 KND92928.1 - 3.4e-55 187.1 0.0 3.9e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 KND92929.1 - 8.7e-29 99.9 44.0 1.3e-05 25.7 0.7 12.9 11 2 2 13 13 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 KND92929.1 - 1.9e-28 96.2 42.0 0.034 14.3 0.0 16.5 18 0 0 18 18 16 9 Tetratricopeptide repeat TPR_1 PF00515.28 KND92929.1 - 8.6e-25 85.5 23.8 0.0019 18.0 0.0 13.7 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 KND92929.1 - 6.6e-24 82.1 20.7 0.46 10.8 0.0 15.4 17 0 0 17 17 16 6 Tetratricopeptide repeat TPR_19 PF14559.6 KND92929.1 - 1.1e-22 80.3 34.9 6.1e-05 23.5 0.1 10.5 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 KND92929.1 - 1.1e-22 78.7 34.6 0.37 11.7 0.0 15.9 13 4 4 17 17 16 7 Tetratricopeptide repeat TPR_17 PF13431.6 KND92929.1 - 3.8e-18 64.5 20.0 0.11 12.9 0.0 13.9 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 KND92929.1 - 5.8e-18 64.3 11.5 0.014 15.1 2.3 10.4 9 1 1 10 10 10 3 TPR repeat TPR_12 PF13424.6 KND92929.1 - 4.5e-16 58.9 46.3 0.0037 17.5 0.2 13.0 11 3 2 14 14 12 5 Tetratricopeptide repeat TPR_7 PF13176.6 KND92929.1 - 8.1e-11 41.2 32.9 0.0014 18.5 0.0 13.2 15 1 1 16 16 14 3 Tetratricopeptide repeat TPR_22 PF18833.1 KND92929.1 - 6e-07 29.5 0.0 2e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND92929.1 - 1.6e-06 28.3 11.9 0.77 10.0 0.0 7.5 8 0 0 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 KND92929.1 - 0.0017 18.8 19.1 2.7 8.9 0.2 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 KND92929.1 - 0.0017 18.8 33.2 49 4.9 0.0 14.9 17 0 0 17 17 15 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND92929.1 - 0.002 18.2 21.8 1.7 8.8 0.0 8.6 8 3 2 10 10 9 1 Tetratricopeptide repeat HemY_N PF07219.13 KND92929.1 - 0.0053 16.9 14.5 0.071 13.3 0.1 6.0 5 1 1 6 6 6 1 HemY protein N-terminus PglL_A PF15864.5 KND92929.1 - 0.011 15.4 1.6 1.5 8.6 0.1 2.8 2 0 0 2 2 2 0 Protein glycosylation ligase Coatomer_WDAD PF04053.14 KND92929.1 - 0.031 13.3 0.1 0.092 11.8 0.0 1.7 2 0 0 2 2 2 0 Coatomer WD associated region DUF4919 PF16266.5 KND92929.1 - 0.044 13.7 0.7 0.71 9.8 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 KND92929.1 - 0.057 13.3 27.6 2.7 8.0 0.0 8.9 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_20 PF14561.6 KND92929.1 - 0.51 10.7 24.7 0.72 10.2 0.5 7.1 6 2 0 8 8 7 0 Tetratricopeptide repeat RPN6_N PF18055.1 KND92929.1 - 0.77 10.1 4.0 4.7 7.6 0.1 3.8 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain NIF3 PF01784.18 KND92930.1 - 9.4e-37 126.9 0.0 1.4e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.11 KND92931.1 - 9.9e-27 92.9 0.0 1.5e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KND92931.1 - 6.2e-05 21.8 0.0 7.5e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Dor1-like family SVIP PF15811.5 KND92931.1 - 0.36 11.3 9.5 0.71 10.4 9.5 1.5 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Adaptin_N PF01602.20 KND92932.1 - 1.4e-137 459.4 2.7 2e-137 458.9 2.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND92932.1 - 3.5e-64 215.7 0.8 3.7e-61 205.9 0.1 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND92932.1 - 1.4e-16 60.7 0.8 5.6e-07 29.9 0.0 5.2 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 KND92932.1 - 1.9e-11 43.2 2.5 0.02 15.1 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KND92932.1 - 5.2e-05 23.6 0.2 0.64 10.6 0.0 4.9 3 1 1 4 4 4 1 HEAT-like repeat Arm PF00514.23 KND92932.1 - 0.0021 18.0 1.1 2.1 8.5 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 KND92932.1 - 0.028 14.0 0.1 1.5 8.3 0.0 3.1 2 1 1 3 3 3 0 CLASP N terminal BolA PF01722.18 KND92933.1 - 5.4e-21 74.6 0.0 1.4e-20 73.3 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein T7SS_ESX1_EccB PF05108.13 KND92934.1 - 0.11 11.2 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B WD40 PF00400.32 KND92935.1 - 3.9e-11 43.3 1.0 0.00017 22.3 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KND92935.1 - 0.0044 16.0 0.1 2.1 7.3 0.1 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KND92935.1 - 0.055 13.8 0.0 4.6 7.6 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Sulfate_transp PF00916.20 KND92936.1 - 2.8e-101 339.0 14.3 3.8e-101 338.6 14.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KND92936.1 - 1.6e-06 27.7 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KND92936.1 - 0.014 15.7 7.5 0.014 15.7 7.5 3.9 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF996 PF06195.13 KND92936.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF996) SGTA_dimer PF16546.5 KND92937.1 - 0.041 13.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Homodimerisation domain of SGTA 7tm_1 PF00001.21 KND92938.1 - 3.5e-07 29.8 4.5 4.8e-07 29.4 4.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KND92938.1 - 1.5e-05 24.5 9.4 2.1e-05 23.9 7.5 1.9 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KND92938.1 - 0.0053 16.5 9.4 0.0098 15.7 9.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 L6_membrane PF05805.12 KND92938.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 1 1 1 2 2 2 0 L6 membrane protein Peptidase_U4 PF03419.13 KND92938.1 - 1.3 8.3 9.2 0.44 9.8 6.1 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Sugar_tr PF00083.24 KND92939.1 - 3.3e-05 22.9 2.4 3.5e-05 22.9 0.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_M3 PF01432.20 KND92940.1 - 3.7e-143 478.1 0.0 4.7e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KND92940.1 - 0.04 12.6 0.0 5.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Angiotensin-converting enzyme MFS_1 PF07690.16 KND92941.1 - 2.2e-35 122.2 21.6 3.2e-35 121.7 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2985 PF11204.8 KND92941.1 - 0.13 12.4 1.6 0.81 9.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) Methyltransf_11 PF08241.12 KND92942.1 - 2.6e-21 76.1 0.0 4.3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92942.1 - 5.5e-19 68.7 0.0 9.3e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND92942.1 - 8.8e-11 42.4 0.0 1.5e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND92942.1 - 8.9e-11 41.8 0.0 1.2e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND92942.1 - 4.9e-09 36.2 0.0 1.3e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND92942.1 - 1.6e-07 30.9 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KND92942.1 - 0.00067 19.2 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KND92942.1 - 0.0047 16.1 0.0 0.0077 15.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 KND92942.1 - 0.012 15.5 0.0 0.055 13.3 0.0 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase MetW PF07021.12 KND92942.1 - 0.032 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KND92942.1 - 0.038 13.3 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 KND92942.1 - 0.049 13.6 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 KND92943.1 - 9.2e-14 51.7 0.3 5.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 KND92943.1 - 1.4e-13 51.0 0.0 3.8e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 KND92943.1 - 3.4e-11 42.1 0.6 0.00016 21.4 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 KND92943.1 - 2.4e-10 39.2 0.5 0.0009 18.6 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 KND92943.1 - 2e-08 33.9 0.1 7.6e-05 22.5 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_14 PF17959.1 KND92943.1 - 0.17 12.3 0.0 19 5.7 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain Adaptin_N PF01602.20 KND92945.1 - 3.7e-124 415.2 10.7 5.4e-124 414.6 10.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND92945.1 - 4.7e-55 186.0 8.1 5.1e-54 182.7 0.2 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND92945.1 - 1.5e-14 54.1 6.4 0.00017 21.9 0.1 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KND92945.1 - 3e-11 42.6 3.3 0.0005 20.1 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KND92945.1 - 8.3e-06 26.2 1.6 20 5.8 0.1 6.3 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 KND92945.1 - 0.00071 19.2 1.9 0.27 10.8 0.0 2.8 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KND92945.1 - 0.0067 16.6 1.3 1.2 9.3 0.0 3.5 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 KND92945.1 - 0.0079 16.2 2.0 1 9.5 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF1077 PF06417.12 KND92946.1 - 6.5e-48 161.6 6.1 8e-48 161.3 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MFS_1 PF07690.16 KND92947.1 - 9.7e-54 182.6 22.4 1.7e-52 178.5 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND92947.1 - 1.8e-07 30.4 9.1 1.8e-07 30.4 9.1 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KND92947.1 - 0.0083 14.6 7.4 0.011 14.1 1.7 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.20 KND92947.1 - 0.062 11.6 0.7 0.12 10.6 0.7 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.29 KND92948.1 - 6.9e-44 149.7 0.0 1.1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND92948.1 - 9.4e-19 67.8 0.0 3.4e-18 66.0 0.0 2.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KND92948.1 - 9.1e-17 61.0 0.0 1.8e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KND92948.1 - 0.0053 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF202 PF02656.15 KND92949.1 - 9e-17 61.3 2.2 4.6e-16 59.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) GWT1 PF06423.12 KND92949.1 - 0.14 12.2 0.3 0.24 11.5 0.3 1.5 1 1 0 1 1 1 0 GWT1 PMT_4TMC PF16192.5 KND92949.1 - 0.42 10.2 3.4 0.25 10.9 0.4 2.0 3 0 0 3 3 3 0 C-terminal four TMM region of protein-O-mannosyltransferase ABC_tran PF00005.27 KND92950.1 - 3.1e-21 76.3 0.0 9.4e-10 39.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KND92950.1 - 1.4e-07 31.6 1.6 0.0046 16.8 0.2 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KND92950.1 - 5.3e-07 29.8 0.1 0.00053 20.2 0.1 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KND92950.1 - 0.0003 21.1 0.0 0.83 9.9 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.6 KND92950.1 - 0.0017 18.9 0.0 0.77 10.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KND92950.1 - 0.002 17.9 0.0 2.9 7.5 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KND92950.1 - 0.0045 17.4 0.1 3.4 8.0 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KND92950.1 - 0.0047 16.6 0.1 0.82 9.5 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KND92950.1 - 0.0098 16.1 0.1 7.4 6.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND92950.1 - 0.017 15.6 0.0 2.9 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KND92950.1 - 0.049 13.4 0.1 3.8 7.2 0.0 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Ploopntkinase1 PF18748.1 KND92950.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 RNA_helicase PF00910.22 KND92950.1 - 0.068 13.6 0.0 13 6.3 0.0 2.6 3 0 0 3 3 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 KND92950.1 - 0.22 10.8 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family UMP1 PF05348.11 KND92951.1 - 1.3e-43 148.0 0.0 1.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 KND92952.1 - 3.7e-12 46.3 0.0 7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KND92952.1 - 0.00017 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KND92952.1 - 0.00099 19.6 0.0 0.0025 18.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 KND92953.1 - 6.6e-42 141.5 6.9 1.6e-08 34.6 0.0 13.7 11 3 5 16 16 16 7 PPR repeat family PPR_3 PF13812.6 KND92953.1 - 1.7e-28 98.5 0.0 0.0025 17.8 0.0 10.9 8 4 4 12 12 12 6 Pentatricopeptide repeat domain PPR PF01535.20 KND92953.1 - 1.8e-26 90.5 25.7 0.00038 20.5 0.0 14.1 17 0 0 17 17 17 5 PPR repeat PPR_1 PF12854.7 KND92953.1 - 2.5e-21 75.0 0.0 1.4e-07 31.1 0.0 9.3 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 KND92953.1 - 1.2e-18 67.3 5.4 2.6e-06 26.9 0.0 6.3 3 2 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KND92953.1 - 0.0027 17.5 0.4 0.4 10.5 0.1 3.5 3 1 1 4 4 4 1 Mitochondrial ATPase expression RPM2 PF08579.11 KND92953.1 - 0.029 14.8 0.0 0.27 11.6 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) COMMD1_N PF17221.3 KND92953.1 - 0.068 13.5 0.1 0.7 10.2 0.0 2.6 2 0 0 2 2 2 0 COMMD1 N-terminal domain SelB-wing_2 PF09106.11 KND92953.1 - 0.15 12.3 0.5 5.5 7.3 0.0 3.9 4 0 0 4 4 4 0 Elongation factor SelB, winged helix DUF3721 PF12518.8 KND92953.1 - 0.16 11.8 0.4 0.42 10.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function GHMP_kinases_N PF00288.26 KND92954.1 - 1e-15 57.7 3.2 2.6e-15 56.4 3.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND92954.1 - 2.1e-08 34.4 0.0 5.8e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Phage-scaffold PF09306.10 KND92954.1 - 0.055 12.8 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein SpoVIF PF14069.6 KND92954.1 - 0.21 11.4 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 Stage VI sporulation protein F Kinesin PF00225.23 KND92955.1 - 2.4e-81 273.2 0.0 3.1e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND92955.1 - 1.6e-22 80.0 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Antimicrobial22 PF16047.5 KND92955.1 - 0.014 15.3 1.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide RNA_pol_Rpo13 PF12136.8 KND92955.1 - 0.065 13.2 0.1 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain HHH_5 PF14520.6 KND92955.1 - 0.13 12.9 0.0 0.39 11.4 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain AIM24 PF01987.17 KND92956.1 - 2.8e-49 167.7 0.1 3.5e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 KND92957.1 - 2.2e-31 109.0 75.5 9.2e-25 87.3 35.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 KND92957.1 - 8.9e-06 24.5 33.5 2.4e-05 23.1 30.7 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Acetyltransf_10 PF13673.7 KND92958.1 - 3.2e-09 36.8 0.0 6e-09 35.9 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND92958.1 - 7.8e-08 32.6 0.0 1.5e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND92958.1 - 4.2e-07 30.3 0.0 8.6e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KND92958.1 - 0.00097 19.2 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KND92958.1 - 0.013 15.4 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 KND92958.1 - 0.018 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zip PF02535.22 KND92961.1 - 8.4e-29 100.8 43.1 2.6e-12 46.6 7.5 3.8 3 1 1 4 4 4 3 ZIP Zinc transporter Peptidase_S8 PF00082.22 KND92962.1 - 1.1e-40 139.8 2.6 1.6e-40 139.3 2.6 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 KND92962.1 - 4.8e-05 24.0 0.0 9.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Tim17 PF02466.19 KND92964.1 - 7e-05 23.2 5.6 0.00015 22.1 5.6 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Wzy_C PF04932.15 KND92964.1 - 0.03 14.0 0.0 0.072 12.7 0.0 1.6 1 1 1 2 2 2 0 O-Antigen ligase MutS_V PF00488.21 KND92965.1 - 5.2e-83 277.7 0.3 8e-83 277.1 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND92965.1 - 3.5e-38 131.8 0.4 1.8e-37 129.4 0.5 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KND92965.1 - 2.6e-22 79.6 1.0 5.2e-20 72.1 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KND92965.1 - 2.5e-18 66.4 0.0 1.9e-17 63.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KND92965.1 - 6.5e-13 48.8 2.6 2.9e-12 46.8 1.9 2.5 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 KND92965.1 - 0.058 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KND92965.1 - 3.1 8.3 4.8 20 5.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.24 KND92966.1 - 4.2e-150 500.6 9.6 4.9e-150 500.4 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 KND92967.1 - 5.1e-22 77.9 0.0 9.6e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 KND92967.1 - 9.7e-21 74.5 0.0 2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KND92967.1 - 2.9e-16 59.4 0.0 8.6e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain MT0933_antitox PF14013.6 KND92967.1 - 0.5 10.7 8.1 1.6 9.1 8.1 1.8 1 0 0 1 1 1 0 MT0933-like antitoxin protein zf_C2H2_10 PF18414.1 KND92968.1 - 0.062 12.8 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger Zn_clus PF00172.18 KND92969.1 - 3.7e-05 23.8 5.8 6.8e-05 22.9 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND92969.1 - 0.12 11.2 0.3 0.27 10.0 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Sld5 PF05916.11 KND92970.1 - 1.4e-30 106.0 0.0 2.1e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Peptidase_M28 PF04389.17 KND92971.1 - 2e-26 93.0 0.1 4.8e-26 91.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KND92971.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Gar1 PF04410.14 KND92972.1 - 4.4e-50 169.5 0.4 9.6e-50 168.3 0.4 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Alpha_GJ PF03229.13 KND92972.1 - 7 7.2 5.8 23 5.5 5.8 1.9 1 0 0 1 1 1 0 Alphavirus glycoprotein J Glyco_transf_22 PF03901.17 KND92973.1 - 7.6e-88 295.5 22.2 8.8e-88 295.3 22.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.25 KND92974.1 - 0.047 13.0 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Asp_protease PF09668.10 KND92975.1 - 2.7e-60 201.6 0.2 4.1e-60 201.0 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KND92975.1 - 3.2e-25 88.5 0.1 9.2e-25 87.0 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KND92975.1 - 5.6e-13 49.3 0.1 1.8e-12 47.7 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KND92975.1 - 2.3e-10 40.1 0.0 4.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 KND92975.1 - 1.5e-05 24.8 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 KND92975.1 - 0.0001 22.1 0.6 0.00022 21.1 0.6 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 KND92975.1 - 0.00019 21.7 0.0 0.0005 20.3 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KND92975.1 - 0.0063 16.3 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 KND92975.1 - 0.013 16.0 0.0 0.027 15.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Acyl-CoA_ox_N PF14749.6 KND92975.1 - 0.35 11.4 1.8 0.66 10.5 1.8 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Acetyltransf_1 PF00583.25 KND92976.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND92976.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND92976.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GATase_6 PF13522.6 KND92977.1 - 1.8e-11 44.4 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KND92977.1 - 6.5e-09 35.8 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KND92977.1 - 2.5e-06 27.1 0.1 5.8e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Methyltransf_8 PF05148.15 KND92978.1 - 9.2e-59 198.9 0.0 4.6e-56 190.1 0.0 3.0 3 1 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KND92978.1 - 0.00012 22.7 0.0 0.00033 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND92978.1 - 0.0049 17.6 0.0 0.17 12.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KND92978.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DUF4100 PF13352.6 KND92978.1 - 0.74 9.6 11.8 1.2 8.8 11.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Proteasome PF00227.26 KND92979.1 - 2.5e-55 186.9 0.1 3.2e-55 186.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KND92979.1 - 1.6e-12 46.8 0.0 3.6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 KND92980.1 - 8.5e-14 51.2 0.0 1.4e-12 47.1 0.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92980.1 - 1.5e-05 25.0 11.7 2.7e-05 24.2 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND92980.1 - 0.04 13.0 0.8 0.092 11.8 0.8 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain SNF2_N PF00176.23 KND92981.1 - 4.5e-71 239.4 0.0 6.4e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND92981.1 - 1e-10 41.9 0.0 3.2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KND92981.1 - 2.7e-06 27.2 2.9 5e-06 26.4 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 KND92981.1 - 7.8e-06 25.8 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KND92981.1 - 0.00062 19.8 0.0 0.0026 17.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KND92981.1 - 0.0031 17.4 2.2 0.01 15.7 2.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND92981.1 - 0.013 15.3 1.3 0.038 13.9 1.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KND92981.1 - 0.076 12.9 0.2 0.076 12.9 0.2 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND92981.1 - 0.098 13.0 2.8 0.065 13.6 0.5 1.9 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KND92981.1 - 0.12 12.5 1.3 0.37 11.0 1.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KND92981.1 - 0.16 11.8 3.2 0.19 11.6 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND92981.1 - 0.2 11.7 2.3 0.27 11.3 0.8 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 KND92981.1 - 0.64 10.4 2.5 1.6 9.0 2.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain GCP_N_terminal PF17681.1 KND92982.1 - 2.6e-62 211.2 0.1 5.5e-62 210.1 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KND92982.1 - 9.9e-60 202.6 4.2 9.9e-60 202.6 4.2 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal HSP70 PF00012.20 KND92983.1 - 1.4e-263 875.5 14.8 1.6e-263 875.3 14.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KND92983.1 - 1e-12 47.5 4.4 9.7e-11 41.1 1.3 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KND92983.1 - 0.00024 20.9 0.1 0.00063 19.5 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SET PF00856.28 KND92983.1 - 0.32 11.4 2.2 0.84 10.0 2.2 1.7 1 0 0 1 1 1 0 SET domain SMBP PF16785.5 KND92983.1 - 0.75 10.0 4.5 0.86 9.8 2.9 2.0 2 0 0 2 2 2 0 Small metal-binding protein SRP68 PF16969.5 KND92984.1 - 1.5e-204 681.1 1.1 1.7e-204 681.0 1.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 HisKA_3 PF07730.13 KND92984.1 - 0.025 15.1 4.5 4.6 7.8 0.0 3.6 4 0 0 4 4 4 0 Histidine kinase YqjK PF13997.6 KND92984.1 - 0.052 13.8 0.1 8.3 6.7 0.0 3.2 2 1 1 3 3 3 0 YqjK-like protein PilJ PF13675.6 KND92984.1 - 0.15 12.0 2.4 0.21 11.6 0.3 2.4 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ribonuclease_T2 PF00445.18 KND92985.1 - 2.5e-31 109.3 0.0 4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Beta-lactamase PF00144.24 KND92986.1 - 3.5e-38 131.7 4.0 5.2e-38 131.1 4.0 1.1 1 0 0 1 1 1 1 Beta-lactamase ABC_membrane PF00664.23 KND92987.1 - 1.4e-42 146.3 11.3 1.7e-42 146.0 11.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KND92987.1 - 1.8e-33 116.0 0.0 8.4e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KND92987.1 - 7.3e-05 23.2 0.1 0.0002 21.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KND92987.1 - 0.00027 20.4 0.0 0.015 14.8 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND92987.1 - 0.0014 18.9 0.0 0.0039 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KND92987.1 - 0.0031 17.4 0.1 0.094 12.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 KND92987.1 - 0.0033 17.5 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND92987.1 - 0.0049 16.8 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KND92987.1 - 0.014 15.5 0.0 0.069 13.2 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KND92987.1 - 0.021 15.3 0.0 0.1 13.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KND92987.1 - 0.023 14.8 0.0 0.061 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KND92987.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KND92987.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KND92987.1 - 0.073 12.8 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KND92987.1 - 0.087 12.1 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 KND92987.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KND92987.1 - 0.095 13.3 0.0 0.4 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KND92987.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin SbcCD_C PF13558.6 KND92987.1 - 0.18 12.1 1.3 1.8 8.9 0.4 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Myb_DNA-bind_6 PF13921.6 KND92988.1 - 1.8e-15 56.9 9.4 1.7e-12 47.4 0.6 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KND92988.1 - 2.6e-15 56.3 4.6 1.3e-08 34.8 0.1 4.0 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KND92988.1 - 0.17 12.3 1.6 0.77 10.2 0.9 2.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 KND92989.1 - 2.7e-10 40.9 0.0 8.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KND92989.1 - 0.00087 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KND92989.1 - 0.02 14.5 0.1 0.21 11.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND92989.1 - 0.039 13.5 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KND92989.1 - 0.054 12.6 0.1 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 KND92989.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KND92989.1 - 0.13 12.5 0.3 0.43 10.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF2859 PF11072.8 KND92989.1 - 0.17 11.6 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) FMO-like PF00743.19 KND92990.1 - 3.9e-38 131.2 0.0 6.3e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND92990.1 - 1.3e-10 41.0 0.0 3.4e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND92990.1 - 1.5e-08 34.2 0.0 8.5e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND92990.1 - 1.5e-06 28.3 0.0 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND92990.1 - 6.1e-05 22.3 0.0 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_2 PF03446.15 KND92990.1 - 0.0021 18.2 1.2 0.0097 16.1 0.3 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Amino_oxidase PF01593.24 KND92990.1 - 0.0033 16.8 0.0 2.8 7.1 0.0 3.0 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 KND92990.1 - 0.016 14.8 0.1 0.27 10.7 0.0 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND92990.1 - 0.053 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KND92990.1 - 0.072 13.1 1.1 5.5 7.0 0.1 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KND92990.1 - 0.39 11.0 1.6 18 5.6 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain QueH PF02677.14 KND92992.1 - 0.072 13.2 0.3 0.072 13.2 0.3 2.0 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH MFS_1 PF07690.16 KND92993.1 - 2.2e-31 109.1 43.2 2.5e-30 105.6 42.5 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily SieB PF14163.6 KND92993.1 - 0.053 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B Orf78 PF06024.12 KND92993.1 - 0.061 13.6 1.2 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) CCSMST1 PF15013.6 KND92993.1 - 0.065 13.4 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 0 CCSMST1 family DUF1772 PF08592.11 KND92993.1 - 1 9.7 10.8 2 8.7 0.1 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF1772) Fringe PF02434.16 KND92994.1 - 2.2e-07 30.6 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 KND92994.1 - 0.0036 17.2 1.7 0.0078 16.1 1.7 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 KND92994.1 - 0.026 14.5 0.1 0.054 13.5 0.1 1.4 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 KND92994.1 - 0.074 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain Cyt_bd_oxida_II PF02322.15 KND92994.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Fungal_trans_2 PF11951.8 KND92995.1 - 3.9e-33 114.8 0.2 1.6e-23 83.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND92995.1 - 1.5e-08 34.6 12.2 2.7e-08 33.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 KND92995.1 - 0.11 12.4 5.1 0.31 11.0 5.1 1.8 1 0 0 1 1 1 0 AT hook motif INCENP_ARK-bind PF03941.15 KND92997.1 - 3.7e-23 81.2 1.7 1.6e-22 79.2 1.7 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region RibD_C PF01872.17 KND92998.1 - 2.4e-35 122.2 0.0 3.9e-35 121.5 0.0 1.3 1 1 0 1 1 1 1 RibD C-terminal domain GTSE1_N PF15259.6 KND92998.1 - 0.03 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 SH3_18 PF18354.1 KND92998.1 - 0.082 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 CarS bacterial SH3 domain G-alpha PF00503.20 KND93000.1 - 5e-113 377.9 2.2 5.7e-113 377.7 2.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KND93000.1 - 1.4e-14 53.9 0.5 1e-08 34.9 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND93000.1 - 9.8e-05 21.8 0.2 0.063 12.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KND93000.1 - 0.0039 17.4 0.1 0.98 9.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 KND93000.1 - 0.04 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 KND93000.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cullin PF00888.22 KND93001.1 - 1e-194 648.7 7.8 1.3e-194 648.4 7.8 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KND93001.1 - 3.6e-25 87.8 6.4 4.8e-25 87.4 2.4 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 KND93001.1 - 0.012 16.2 2.4 0.058 13.9 0.4 3.1 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF2877 PF11392.8 KND93001.1 - 0.17 12.6 0.1 0.83 10.4 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) ABC_tran PF00005.27 KND93002.1 - 2.7e-51 173.7 0.0 6.6e-29 101.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KND93002.1 - 3.9e-38 131.7 27.4 4.3e-20 72.5 15.3 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KND93002.1 - 4.4e-10 39.4 2.0 0.014 14.8 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND93002.1 - 1.2e-08 34.6 0.8 0.0013 18.4 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KND93002.1 - 6.3e-08 33.4 0.1 3.7e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND93002.1 - 3.4e-06 27.1 0.1 0.0085 16.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 KND93002.1 - 4.1e-06 26.5 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KND93002.1 - 5.8e-06 26.3 0.1 0.037 13.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KND93002.1 - 1.6e-05 25.2 0.3 0.66 10.3 0.0 3.7 6 0 0 6 6 3 2 AAA domain AAA_16 PF13191.6 KND93002.1 - 1.9e-05 25.1 0.1 0.17 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KND93002.1 - 7.1e-05 22.9 0.5 0.07 13.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 KND93002.1 - 9.3e-05 21.7 0.9 0.47 9.6 0.1 3.8 2 2 0 2 2 2 1 NB-ARC domain DUF87 PF01935.17 KND93002.1 - 0.0002 21.5 2.8 0.0053 16.9 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 KND93002.1 - 0.00028 21.0 1.7 0.19 11.8 0.1 2.5 2 0 0 2 2 2 2 Dynamin family SbcCD_C PF13558.6 KND93002.1 - 0.0027 17.9 0.0 1.5 9.1 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KND93002.1 - 0.0027 17.6 0.2 2.6 8.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.18 KND93002.1 - 0.0032 16.9 0.1 0.42 9.9 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 KND93002.1 - 0.0036 17.1 0.0 2.8 7.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KND93002.1 - 0.0054 15.8 0.9 1.4 7.9 0.2 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.19 KND93002.1 - 0.013 15.1 1.1 2.2 7.8 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KND93002.1 - 0.024 14.5 0.6 6.7 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase Septin PF00735.18 KND93002.1 - 0.038 13.3 0.1 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 KND93002.1 - 0.04 13.6 2.1 1.4 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 KND93002.1 - 0.054 13.7 0.1 8.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KND93002.1 - 0.058 13.6 0.1 9.3 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KND93002.1 - 0.069 12.4 0.2 0.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KND93002.1 - 0.089 12.3 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KND93002.1 - 0.1 12.0 2.9 0.77 9.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein CbiA PF01656.23 KND93002.1 - 0.11 12.6 0.1 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.6 KND93002.1 - 0.14 11.8 0.0 5.6 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 KND93002.1 - 0.16 11.7 0.4 19 4.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KND93002.1 - 0.16 11.2 0.4 2.9 7.1 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 KND93002.1 - 0.16 11.7 0.6 6.9 6.4 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 KND93002.1 - 0.17 11.2 0.3 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 AIG1 family DAP3 PF10236.9 KND93002.1 - 0.23 10.6 1.9 6.2 5.9 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CorA PF01544.18 KND93003.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SPW PF03779.14 KND93004.1 - 0.59 9.8 6.1 4.8 6.8 2.0 2.5 1 1 1 2 2 2 0 SPW repeat Pkinase PF00069.25 KND93005.1 - 7.5e-44 150.1 0.0 1.1e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93005.1 - 2.4e-16 59.8 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND93005.1 - 0.00014 21.0 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KND93005.1 - 0.0011 18.9 1.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND93005.1 - 0.039 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPTA PF01239.22 KND93006.1 - 6.2e-38 127.4 4.3 2.7e-08 33.3 0.1 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Ank_5 PF13857.6 KND93006.1 - 0.043 14.1 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3950 PF13132.6 KND93006.1 - 0.14 11.9 0.3 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) Sec34 PF04136.15 KND93008.1 - 1.2e-48 164.8 0.4 3.1e-48 163.4 0.4 1.8 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 KND93008.1 - 0.2 11.5 3.4 2.8 7.7 0.1 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 RCC1 PF00415.18 KND93009.1 - 4.6e-22 78.4 5.6 7.7e-07 29.6 0.0 7.0 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KND93009.1 - 3.3e-11 42.7 0.1 3.2e-08 33.2 0.0 6.7 8 1 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat Y_phosphatase PF00102.27 KND93010.1 - 4.9e-48 163.8 0.0 7.6e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KND93010.1 - 0.00014 22.1 0.0 0.00059 20.0 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KND93010.1 - 0.0049 16.9 0.0 0.0085 16.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KND93010.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Prefoldin PF02996.17 KND93013.1 - 2.5e-34 117.8 0.1 2.5e-34 117.8 0.1 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KND93013.1 - 0.0013 18.7 3.9 0.019 14.9 0.0 2.9 1 1 1 3 3 3 1 Prefoldin subunit DUF4201 PF13870.6 KND93013.1 - 0.011 15.4 3.7 0.5 10.1 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Filament PF00038.21 KND93013.1 - 0.013 15.1 4.0 0.29 10.7 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein VanZ PF04892.12 KND93014.1 - 3e-05 24.7 2.0 4.3e-05 24.2 2.0 1.2 1 0 0 1 1 1 1 VanZ like family Phage_holin_2_4 PF16082.5 KND93014.1 - 0.035 13.8 0.1 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Bromodomain PF00439.25 KND93015.1 - 1.3e-19 70.1 1.4 3e-19 68.9 0.4 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 KND93015.1 - 7e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PSII_Pbs27 PF13326.6 KND93015.1 - 0.026 14.8 0.1 0.074 13.4 0.1 1.8 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF2870 PF11069.8 KND93015.1 - 0.068 13.6 0.0 0.43 11.0 0.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) ING PF12998.7 KND93015.1 - 0.12 12.9 4.5 3.2 8.4 1.0 2.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SHMT PF00464.19 KND93016.1 - 2.6e-203 675.0 0.0 3e-203 674.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KND93016.1 - 6.8e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND93016.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND93016.1 - 0.08 12.2 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Ferric_reduct PF01794.19 KND93017.1 - 1e-15 58.0 12.5 2.2e-15 56.9 12.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KND93017.1 - 5e-13 49.4 0.0 1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KND93017.1 - 3.9e-08 33.3 0.0 1.4e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Serglycin PF04360.12 KND93017.1 - 1.8e-06 27.9 0.3 3.3e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Serglycin NAD_binding_1 PF00175.21 KND93017.1 - 0.00051 20.7 0.1 0.031 14.9 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain AF-4 PF05110.13 KND93017.1 - 0.32 9.0 0.0 0.41 8.7 0.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ADH_zinc_N PF00107.26 KND93018.1 - 3.3e-17 62.7 0.6 4.9e-17 62.1 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND93018.1 - 7.2e-10 40.0 0.1 2.1e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND93018.1 - 0.0002 21.2 0.0 0.0007 19.5 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.6 KND93018.1 - 0.2 12.1 0.3 0.42 11.1 0.3 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding KH_8 PF17903.1 KND93019.1 - 1.4e-30 105.2 0.0 2.7e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KND93019.1 - 0.026 14.4 0.0 0.14 12.0 0.0 2.3 1 1 0 1 1 1 0 KH domain Acyltransf_C PF16076.5 KND93019.1 - 0.087 12.9 0.7 0.99 9.5 0.6 2.4 2 0 0 2 2 2 0 Acyltransferase C-terminus PI3_PI4_kinase PF00454.27 KND93020.1 - 3e-45 155.0 0.0 4.5e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_25 PF13649.6 KND93021.1 - 6.8e-15 55.6 0.0 1.5e-14 54.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND93021.1 - 1.2e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND93021.1 - 1.7e-12 47.8 0.0 2.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND93021.1 - 5.4e-10 39.3 0.0 1.3e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND93021.1 - 1.6e-09 38.4 0.0 2.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND93021.1 - 0.0002 20.9 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KND93021.1 - 0.00054 19.4 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KND93021.1 - 0.0031 16.9 0.0 0.0096 15.2 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KND93021.1 - 0.036 13.6 0.0 0.047 13.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KND93021.1 - 0.11 12.6 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KND93021.1 - 0.29 9.6 0.3 0.9 8.0 0.3 1.7 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_3 PF13302.7 KND93022.1 - 6.7e-10 39.8 0.0 9e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND93022.1 - 4.9e-09 36.4 0.0 8.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KND93022.1 - 1.1e-06 28.9 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND93022.1 - 0.0025 18.2 0.0 0.004 17.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND93022.1 - 0.0041 17.1 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KND93022.1 - 0.017 14.8 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 KND93023.1 - 7.7e-20 71.1 0.1 1.7e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND93023.1 - 6.5e-10 39.0 0.2 1.2e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Ribonuc_L-PSP PF01042.21 KND93024.1 - 1.3e-26 93.0 0.0 1.4e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulf_transp PF04143.14 KND93025.1 - 1.6e-29 103.5 29.3 1.6e-29 103.5 29.3 1.5 1 1 0 1 1 1 1 Sulphur transport YqeY PF09424.10 KND93027.1 - 9.9e-23 80.8 6.3 1.2e-22 80.6 6.3 1.1 1 0 0 1 1 1 1 Yqey-like protein POTRA_2 PF08479.11 KND93027.1 - 0.084 12.7 0.1 0.99 9.3 0.0 2.3 1 1 1 2 2 2 0 POTRA domain, ShlB-type Sec62 PF03839.16 KND93028.1 - 3.3e-67 226.2 5.2 3.3e-67 226.2 5.2 2.0 2 0 0 2 2 2 1 Translocation protein Sec62 DUF2207 PF09972.9 KND93028.1 - 0.11 11.3 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Zip PF02535.22 KND93028.1 - 0.25 10.5 4.4 21 4.2 0.0 2.3 2 1 1 3 3 3 0 ZIP Zinc transporter SelP_N PF04592.14 KND93028.1 - 1.8 7.9 10.6 3.9 6.8 10.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AC_N PF16214.5 KND93028.1 - 2.3 7.3 4.3 0.91 8.6 0.2 2.2 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TFIIA PF03153.13 KND93028.1 - 5.4 6.9 15.3 0.29 11.1 9.5 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Corona_M PF01635.18 KND93028.1 - 6.8 5.9 8.3 11 5.3 8.3 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Acetyltransf_1 PF00583.25 KND93029.1 - 1.9e-09 37.8 0.0 2.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND93029.1 - 3.1e-08 33.6 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND93029.1 - 3.4e-08 33.3 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KND93029.1 - 2.9e-06 27.6 0.0 4.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND93029.1 - 6.9e-05 23.5 0.0 8.5e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 KND93030.1 - 5.2e-13 49.3 3.3 2.1e-08 34.4 0.5 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KND93030.1 - 0.00024 21.3 0.0 0.41 10.9 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MerR_1 PF13411.6 KND93030.1 - 0.19 11.8 0.0 6.4 7.0 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein p450 PF00067.22 KND93031.1 - 6.1e-67 226.3 0.0 1.9e-40 139.0 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 FYRC PF05965.14 KND93031.1 - 0.042 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 F/Y rich C-terminus Aldedh PF00171.22 KND93032.1 - 9.3e-165 548.6 0.3 2.6e-152 507.6 0.1 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family FAD_binding_3 PF01494.19 KND93033.1 - 4.4e-81 272.8 0.0 5.7e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KND93033.1 - 0.002 17.4 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND93033.1 - 0.045 14.0 1.1 0.12 12.6 1.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 KND93033.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 KND93033.1 - 0.099 11.7 0.1 0.22 10.5 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KND93033.1 - 0.33 10.1 0.8 0.53 9.5 0.8 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KND93034.1 - 7.1e-15 54.4 0.1 9.4e-14 50.7 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND93034.1 - 1.1e-09 38.0 0.0 8.6e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND93034.1 - 9e-08 31.7 0.0 1.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND93034.1 - 1.6e-07 30.8 0.0 2.4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KND93034.1 - 2.7e-07 30.7 0.0 6.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND93034.1 - 0.00043 19.5 0.1 0.83 8.7 0.1 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KND93034.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KND93034.1 - 0.02 14.2 0.5 0.071 12.3 0.1 2.0 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 KND93034.1 - 0.02 14.5 0.2 0.39 10.2 0.1 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KND93034.1 - 0.044 13.1 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain N2227 PF07942.12 KND93034.1 - 0.061 12.5 1.0 0.26 10.4 1.0 1.8 1 1 0 1 1 1 0 N2227-like protein Shikimate_DH PF01488.20 KND93034.1 - 0.064 13.3 0.1 5.7 7.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 KND93035.1 - 1.8e-55 188.1 2.6 6.8e-27 94.5 0.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND93035.1 - 7.2e-40 136.5 4.1 1.3e-24 86.8 0.6 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KND93035.1 - 1.5e-06 28.2 3.2 1.4e-05 25.1 1.0 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 KND93035.1 - 0.0028 17.2 0.3 0.01 15.3 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KND93035.1 - 0.13 12.1 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2463 PF09591.10 KND93036.1 - 0.0042 17.0 1.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2463) HSF_DNA-bind PF00447.17 KND93037.1 - 2.8e-29 101.6 0.4 5.1e-29 100.7 0.4 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KND93037.1 - 9.3e-19 67.7 0.0 9.5e-18 64.4 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain NPV_P10 PF05531.12 KND93037.1 - 0.049 14.1 0.8 0.096 13.2 0.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MIS13 PF08202.11 KND93037.1 - 0.063 12.6 0.1 0.092 12.0 0.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family PCRF PF03462.18 KND93037.1 - 0.13 12.1 0.5 14 5.5 0.0 2.3 2 0 0 2 2 2 0 PCRF domain CENP-H PF05837.12 KND93037.1 - 0.14 12.6 1.8 0.27 11.6 1.8 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) partial_CstF PF15861.5 KND93037.1 - 0.15 11.8 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain YabA PF06156.13 KND93037.1 - 0.2 12.3 2.5 0.41 11.3 2.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA W2 PF02020.18 KND93038.1 - 9.7e-22 76.9 2.0 2.4e-21 75.7 2.0 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KND93038.1 - 7.4e-11 41.3 8.1 1.5e-06 27.7 3.3 3.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KND93038.1 - 5.1e-05 22.9 6.6 0.0015 18.2 1.9 2.9 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KND93038.1 - 0.00024 19.4 0.1 0.00037 18.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KND93038.1 - 0.0011 18.1 0.5 0.0017 17.4 0.5 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 KND93038.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KND93038.1 - 0.0021 18.4 0.0 0.007 16.7 0.0 2.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain UDPGT PF00201.18 KND93039.1 - 7.4e-11 41.5 0.0 9.2e-09 34.6 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 KND93039.1 - 0.0032 17.5 1.5 0.0078 16.2 1.5 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_28 PF03033.20 KND93039.1 - 0.0064 16.5 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.6 KND93039.1 - 0.012 16.0 6.1 0.012 16.0 6.1 2.5 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Glyco_trans_1_3 PF13528.6 KND93039.1 - 0.067 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 KND93039.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ribosomal_S17 PF00366.20 KND93040.1 - 2.3e-21 75.7 1.1 2.3e-21 75.7 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 EMG1 PF03587.14 KND93041.1 - 1.2e-79 266.5 0.1 1.4e-79 266.3 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DnaJ PF00226.31 KND93042.1 - 1.2e-21 76.5 2.4 1.2e-21 76.5 2.4 2.3 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 KND93042.1 - 7.9e-21 72.9 0.1 0.0037 17.0 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KND93042.1 - 4.4e-17 60.7 9.9 0.012 15.7 0.1 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 KND93042.1 - 1.7e-16 60.1 5.5 0.0007 19.7 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KND93042.1 - 1.3e-13 50.0 2.6 0.034 14.4 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND93042.1 - 2.8e-13 50.2 8.1 1.3e-05 25.6 0.1 5.5 2 1 5 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KND93042.1 - 3.3e-11 43.0 12.4 0.083 13.7 0.2 7.7 4 4 4 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KND93042.1 - 3.5e-11 42.7 4.2 0.00024 21.3 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND93042.1 - 2.1e-08 34.7 8.2 2.4 8.9 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KND93042.1 - 8.8e-08 32.3 6.8 0.66 10.2 0.6 4.8 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KND93042.1 - 5.6e-07 29.1 14.0 0.043 13.5 0.2 5.9 5 2 2 7 7 7 4 TPR repeat TPR_6 PF13174.6 KND93042.1 - 5e-06 26.8 10.7 4.9 8.0 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KND93042.1 - 2.5e-05 23.2 0.7 0.005 15.6 0.2 3.3 2 1 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 KND93042.1 - 8.5e-05 22.8 9.8 0.35 11.2 0.7 5.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND93042.1 - 0.00038 20.3 5.3 2.3 8.5 0.1 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 KND93042.1 - 0.11 12.8 2.1 3.2 8.1 0.2 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KND93042.1 - 0.19 11.9 1.6 12 6.1 0.0 3.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KND93042.1 - 0.93 9.9 9.2 10 6.5 0.0 4.6 3 2 2 5 5 5 0 Bacterial transcriptional activator domain APG9 PF04109.16 KND93043.1 - 3.5e-194 646.3 14.5 4.1e-194 646.1 14.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.11 KND93044.1 - 1.5e-197 657.8 0.1 1.7e-197 657.6 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG5 PF10392.9 KND93044.1 - 0.01 16.0 0.3 0.061 13.5 0.1 2.5 3 0 0 3 3 3 0 Golgi transport complex subunit 5 KfrA_N PF11740.8 KND93044.1 - 0.07 13.8 0.4 1.6 9.4 0.4 2.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term AAA PF00004.29 KND93045.1 - 2.9e-38 131.3 0.0 5.5e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KND93045.1 - 1.1e-06 28.5 0.0 3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 KND93045.1 - 1.2e-05 25.6 0.6 0.00076 19.8 0.1 3.3 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 KND93045.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND93045.1 - 0.00051 20.5 1.2 0.0033 17.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KND93045.1 - 0.00056 19.2 0.0 0.0009 18.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KND93045.1 - 0.00089 19.3 0.2 0.0035 17.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 KND93045.1 - 0.0014 18.4 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KND93045.1 - 0.0027 17.8 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KND93045.1 - 0.0036 17.0 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KND93045.1 - 0.0037 16.7 0.1 0.0099 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KND93045.1 - 0.0073 16.3 0.0 0.097 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND93045.1 - 0.02 15.1 0.0 0.062 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KND93045.1 - 0.02 14.1 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 KND93045.1 - 0.046 13.6 0.1 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 KND93045.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KND93045.1 - 0.056 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND93045.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KND93045.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND93045.1 - 0.18 11.0 0.1 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 KND93045.1 - 0.2 11.3 0.0 0.47 10.1 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 KND93045.1 - 0.24 10.8 0.0 0.51 9.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein FA_desaturase PF00487.24 KND93046.1 - 4.3e-29 102.1 25.2 7.7e-29 101.3 25.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KND93046.1 - 4.2e-11 42.8 0.0 1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Vac14_Fig4_bd PF11916.8 KND93047.1 - 3.2e-79 264.8 5.0 3.2e-79 264.8 5.0 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KND93047.1 - 7.5e-47 157.9 0.1 8.3e-41 138.5 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KND93047.1 - 1.3e-09 37.5 0.1 0.00066 19.7 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 KND93047.1 - 1.2e-08 35.2 2.7 0.0023 18.4 0.2 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KND93047.1 - 6.4e-07 29.5 0.8 0.013 15.6 0.3 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KND93047.1 - 0.00026 21.3 0.5 1.2 9.6 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats Arm PF00514.23 KND93047.1 - 0.002 18.1 0.0 0.74 9.9 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 KND93047.1 - 0.044 13.3 0.4 7 6.1 0.0 3.6 4 0 0 4 4 4 0 Tti2 family BUD22 PF09073.10 KND93047.1 - 0.11 11.9 1.5 0.16 11.3 1.5 1.2 1 0 0 1 1 1 0 BUD22 CENP-F_leu_zip PF10473.9 KND93048.1 - 0.048 13.7 1.0 2.2 8.3 0.1 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRISPR_Cas2 PF09827.9 KND93048.1 - 0.17 12.1 0.0 0.49 10.6 0.0 1.7 2 0 0 2 2 2 0 CRISPR associated protein Cas2 Mito_carr PF00153.27 KND93049.1 - 7.2e-51 170.1 6.4 6.4e-22 77.3 0.1 4.8 3 2 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 KND93049.1 - 0.085 12.0 2.1 1.6 7.8 0.1 2.8 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Goodbye PF17109.5 KND93052.1 - 5.2e-06 26.9 0.0 8.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain Methyltransf_PK PF05891.12 KND93053.1 - 5.3e-77 258.2 0.0 6.1e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KND93053.1 - 1.1e-05 26.1 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND93053.1 - 0.00013 22.6 0.0 0.0002 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND93053.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KND93053.1 - 0.059 12.7 0.1 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase domain COA2 PF17051.5 KND93054.1 - 0.00018 21.5 0.0 0.00026 21.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Presenilin PF01080.17 KND93055.1 - 0.024 13.4 6.2 0.024 13.4 6.2 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 KND93055.1 - 0.067 12.4 3.0 0.086 12.0 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 KND93055.1 - 0.08 12.3 9.2 0.11 11.9 9.2 1.1 1 0 0 1 1 1 0 FAM76 protein Tim54 PF11711.8 KND93055.1 - 0.08 11.7 6.3 0.093 11.5 6.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 KND93055.1 - 0.089 12.8 1.4 0.11 12.5 1.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region REC114-like PF15165.6 KND93055.1 - 0.17 11.7 2.7 0.27 11.0 2.7 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like CDC45 PF02724.14 KND93055.1 - 0.28 9.4 6.3 0.3 9.3 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 KND93055.1 - 0.37 9.8 8.4 0.44 9.5 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 KND93055.1 - 0.42 9.3 10.1 0.48 9.2 10.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 KND93055.1 - 0.99 9.1 3.9 1.3 8.7 3.9 1.2 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 KND93055.1 - 1.4 8.6 6.0 2.4 7.8 6.0 1.4 1 0 0 1 1 1 0 FAM176 family RP-C_C PF11800.8 KND93055.1 - 2.9 7.9 6.4 4.3 7.4 6.4 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region ALMT PF11744.8 KND93055.1 - 3.3 6.4 5.0 4 6.2 5.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Stomoxyn PF11585.8 KND93056.1 - 0.52 10.4 2.6 3.5 7.7 1.0 2.3 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn AFG1_ATPase PF03969.16 KND93058.1 - 2.8e-94 316.0 0.0 2.2e-90 303.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 KND93058.1 - 0.0013 18.6 0.0 1.7 8.5 0.0 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.6 KND93058.1 - 0.0017 18.7 0.0 0.48 10.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND93058.1 - 0.011 16.0 0.0 0.045 14.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND93058.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tom37_C PF11801.8 KND93058.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain SH3_9 PF14604.6 KND93059.1 - 8e-11 41.6 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND93059.1 - 2e-06 27.3 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KND93059.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CVNH PF08881.10 KND93060.1 - 7.6e-12 45.8 0.1 1.1e-11 45.4 0.1 1.3 1 0 0 1 1 1 1 CVNH domain Casein_kappa PF00997.18 KND93060.1 - 0.2 11.7 0.0 0.29 11.2 0.0 1.1 1 0 0 1 1 1 0 Kappa casein Metallophos PF00149.28 KND93062.1 - 1.3e-30 107.4 0.0 5.7e-22 79.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PKHD_C PF18331.1 KND93062.1 - 0.068 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain RPAP1_C PF08620.10 KND93063.1 - 1e-26 92.8 1.0 1.8e-26 92.1 0.1 1.9 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KND93063.1 - 6.2e-18 64.3 2.2 1.1e-17 63.5 2.2 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal NPH-II PF12011.8 KND93063.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NPH-II eIF2A PF08662.11 KND93064.1 - 4e-76 255.2 0.0 8.7e-76 254.1 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KND93064.1 - 0.068 14.1 0.4 3.9 8.5 0.0 3.6 3 1 1 4 4 4 0 WD domain, G-beta repeat CP2 PF04516.15 KND93065.1 - 3e-79 265.5 0.0 4.8e-79 264.9 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KND93065.1 - 0.081 11.7 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Tektin family SesA PF17107.5 KND93066.1 - 3.3e-07 30.5 0.1 3.5e-06 27.2 0.0 2.8 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KND93066.1 - 3.1e-06 27.2 0.0 9.5e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND93066.1 - 0.00017 22.0 3.1 0.0063 16.9 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain NB-ARC PF00931.22 KND93066.1 - 0.018 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma70_ner PF04546.13 KND93066.1 - 0.023 14.6 2.1 1.6 8.6 1.6 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region ABC_tran PF00005.27 KND93066.1 - 0.027 15.0 0.1 0.069 13.7 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KND93066.1 - 0.034 14.7 0.2 7.9 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KND93066.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KND93066.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KND93066.1 - 0.07 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 KND93067.1 - 2.3e-33 115.6 34.2 2.3e-33 115.6 34.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93067.1 - 1.3e-08 34.2 8.5 1.3e-08 34.2 8.5 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Nucleocapsid-N PF11030.8 KND93069.1 - 0.54 10.2 5.2 0.67 9.9 5.2 1.1 1 0 0 1 1 1 0 Nucleocapsid protein N Zn_clus PF00172.18 KND93071.1 - 7.4e-06 26.0 12.8 1.2e-05 25.3 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 KND93072.1 - 5.5e-78 261.2 47.2 1.4e-41 142.2 21.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KND93072.1 - 1.8e-36 125.7 0.0 3.6e-17 63.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KND93072.1 - 2.3e-35 120.4 2.4 7.7e-31 105.8 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KND93072.1 - 5.9e-16 58.8 0.0 1.7e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KND93072.1 - 3.2e-07 30.9 0.2 0.0045 17.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KND93072.1 - 5.4e-07 29.4 0.8 1.7e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KND93072.1 - 9.5e-07 28.9 0.2 0.00027 20.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KND93072.1 - 2.7e-06 27.6 0.1 0.0018 18.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KND93072.1 - 4.1e-06 26.1 33.6 0.00016 20.9 17.8 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KND93072.1 - 6.6e-06 26.7 0.0 0.0019 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KND93072.1 - 3.5e-05 23.4 1.1 0.012 15.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KND93072.1 - 6.8e-05 22.8 0.0 0.34 10.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 KND93072.1 - 0.00036 21.0 0.2 1.1 9.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KND93072.1 - 0.0013 19.0 0.2 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KND93072.1 - 0.0013 18.2 0.0 0.56 9.6 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KND93072.1 - 0.0058 16.4 0.3 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KND93072.1 - 0.013 15.1 0.7 0.49 10.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KND93072.1 - 0.022 14.7 2.5 1.7 8.5 0.2 2.9 3 0 0 3 3 2 0 NACHT domain AAA_22 PF13401.6 KND93072.1 - 0.025 14.8 1.9 1.8 8.8 0.2 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KND93072.1 - 0.037 14.1 0.1 9.6 6.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KND93072.1 - 0.067 13.6 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pax2_C PF12403.8 KND93072.1 - 0.074 13.1 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Paired-box protein 2 C terminal AAA_23 PF13476.6 KND93072.1 - 0.15 12.5 0.1 0.49 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DinB_2 PF12867.7 KND93072.1 - 0.18 12.3 1.2 16 6.0 0.1 3.2 3 0 0 3 3 3 0 DinB superfamily Evr1_Alr PF04777.13 KND93073.1 - 1.5e-30 105.6 0.1 5.7e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family Ldh_2 PF02615.14 KND93073.1 - 0.37 9.9 1.8 0.85 8.7 0.0 1.9 1 1 1 2 2 2 0 Malate/L-lactate dehydrogenase TPP_enzyme_N PF02776.18 KND93074.1 - 2.2e-32 112.0 0.2 4e-32 111.2 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KND93074.1 - 1.3e-21 76.8 0.0 3.1e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KND93074.1 - 2.4e-15 56.6 0.1 3.1e-14 53.0 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain THUMP PF02926.17 KND93074.1 - 5.9e-11 42.7 2.0 6.4e-10 39.3 1.5 2.7 2 1 0 2 2 2 1 THUMP domain Pkinase PF00069.25 KND93075.1 - 7.5e-50 169.7 0.0 1.1e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93075.1 - 8.4e-20 71.1 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KND93075.1 - 0.0028 17.0 0.2 0.0044 16.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gag_p6 PF08705.11 KND93075.1 - 0.014 15.7 0.2 0.025 14.8 0.2 1.4 1 0 0 1 1 1 0 Gag protein p6 Kinase-like PF14531.6 KND93075.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like S_100 PF01023.19 KND93075.1 - 0.02 14.6 0.2 0.056 13.1 0.2 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Haspin_kinase PF12330.8 KND93075.1 - 0.025 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 KND93075.1 - 0.026 14.4 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KND93075.1 - 0.067 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.15 KND93076.1 - 2.1e-35 122.2 0.0 2.7e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Sec23_trunk PF04811.15 KND93078.1 - 9.5e-71 238.2 0.0 2.7e-70 236.7 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KND93078.1 - 5.5e-23 80.8 0.0 2.5e-22 78.6 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KND93078.1 - 6e-18 65.4 0.0 1.3e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KND93078.1 - 5.6e-17 61.5 4.7 1e-16 60.7 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KND93078.1 - 5.8e-09 35.7 0.0 1.9e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KND93078.1 - 0.016 14.6 0.1 0.034 13.5 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF917 PF06032.12 KND93079.1 - 1.3e-123 412.3 1.0 2.2e-123 411.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 KND93079.1 - 4.7e-27 95.0 9.9 4.7e-26 91.7 1.4 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KND93079.1 - 7.3e-23 81.2 8.9 8.1e-23 81.0 0.4 3.5 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MreB_Mbl PF06723.13 KND93079.1 - 0.0077 15.1 0.1 0.018 13.9 0.1 1.6 1 0 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 KND93079.1 - 0.057 12.6 1.1 3 7.0 0.1 3.3 4 0 0 4 4 4 0 StbA protein MutL PF13941.6 KND93079.1 - 1.2 7.7 7.5 4 5.9 0.2 2.9 3 0 0 3 3 3 0 MutL protein Zn_clus PF00172.18 KND93080.1 - 5.3e-06 26.4 11.4 5.3e-06 26.4 11.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc42p PF11544.8 KND93080.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Spindle pole body component Spc42p SGT1 PF07093.11 KND93082.1 - 9.4e-91 305.0 20.4 1.4e-86 291.2 0.0 2.2 1 1 1 2 2 2 2 SGT1 protein CDC45 PF02724.14 KND93082.1 - 2.3 6.4 13.1 4.2 5.5 13.1 1.5 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 KND93083.1 - 3.8e-68 229.8 0.1 5.8e-68 229.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND93083.1 - 9.1e-16 58.2 0.0 2.5e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 KND93083.1 - 4.7e-12 45.7 0.1 1.6e-10 40.8 0.0 2.9 2 1 0 2 2 2 1 HIRAN domain zf-C3HC4_2 PF13923.6 KND93083.1 - 2.5e-08 33.6 12.0 8.9e-08 31.9 12.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND93083.1 - 2.8e-08 33.5 12.4 1.7e-07 31.0 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND93083.1 - 5.4e-07 29.4 13.7 5.4e-07 29.4 13.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND93083.1 - 5.5e-07 29.4 11.3 5.5e-07 29.4 11.3 2.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND93083.1 - 9.4e-07 29.1 13.4 1.7e-06 28.2 11.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KND93083.1 - 1e-06 28.6 6.9 4.7e-06 26.5 6.8 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KND93083.1 - 3e-05 24.2 6.0 7.5e-05 22.9 6.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND93083.1 - 5.4e-05 23.0 11.8 5.4e-05 23.0 11.8 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 ResIII PF04851.15 KND93083.1 - 0.00022 21.3 0.0 0.00063 19.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_10 PF16685.5 KND93083.1 - 0.0021 18.2 9.9 0.0021 18.2 9.9 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 KND93083.1 - 0.0039 17.3 11.1 0.0039 17.3 11.1 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KND93083.1 - 0.0096 16.0 2.7 0.021 14.8 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND93083.1 - 0.022 14.5 4.3 0.058 13.2 4.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KND93083.1 - 0.032 14.1 4.7 0.092 12.6 4.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HAD_SAK_2 PF18143.1 KND93083.1 - 0.084 13.2 0.2 0.62 10.4 0.0 2.6 1 1 1 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins zf-P11 PF03854.14 KND93083.1 - 0.76 9.5 6.5 5.1 6.9 6.3 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-Nse PF11789.8 KND93083.1 - 5.5 6.9 9.1 18 5.2 8.5 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Filament_head PF04732.14 KND93083.1 - 5.9 7.8 7.5 70 4.4 6.7 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region NCA2 PF08637.10 KND93084.1 - 6.6e-107 357.0 0.0 1.2e-106 356.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.6 KND93084.1 - 0.18 10.8 0.2 0.28 10.1 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FA_hydroxylase PF04116.13 KND93085.1 - 1.2e-24 87.1 12.9 1.2e-24 87.1 12.9 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily CDO_I PF05995.12 KND93086.1 - 1.4e-43 148.1 0.0 1.8e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 KND93086.1 - 0.051 13.0 0.3 0.08 12.4 0.3 1.5 1 1 0 1 1 1 0 PCO_ADO SLAC1 PF03595.17 KND93087.1 - 6.1e-75 252.5 44.0 1.8e-62 211.5 31.5 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel AHL_synthase PF17327.2 KND93088.1 - 0.31 10.0 0.0 0.43 9.5 0.0 1.1 1 0 0 1 1 1 0 Acyl homoserine lactone synthase Aminotran_1_2 PF00155.21 KND93092.1 - 4.6e-61 207.0 0.0 5.6e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KND93092.1 - 0.062 12.2 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Allinase Glyco_hydro_76 PF03663.14 KND93093.1 - 4.5e-138 460.7 7.0 5.6e-138 460.4 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND93093.1 - 0.0003 20.0 6.1 0.26 10.3 0.1 3.2 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KND93093.1 - 0.015 13.8 0.4 0.72 8.3 0.0 2.4 2 1 1 3 3 3 0 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 KND93093.1 - 0.067 12.4 1.0 0.9 8.7 0.2 2.3 1 1 1 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Nrap_D4 PF17405.2 KND93096.1 - 5.3e-61 205.7 0.0 9.2e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 KND93096.1 - 1.4e-60 203.7 0.9 6.7e-60 201.5 0.6 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 KND93096.1 - 1.3e-51 174.3 0.3 2e-48 164.0 0.0 2.6 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 KND93096.1 - 1.3e-45 155.2 0.0 2.2e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 KND93096.1 - 3.1e-44 150.9 0.0 7.1e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 KND93096.1 - 2e-36 125.2 0.0 7.3e-36 123.4 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 6 I-set PF07679.16 KND93097.1 - 7.4e-06 25.9 0.3 0.6 10.2 0.0 4.2 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.11 KND93097.1 - 0.001 18.6 3.3 4.6 6.9 0.0 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF1918) SelP_N PF04592.14 KND93097.1 - 8.5 5.7 8.4 17 4.7 8.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_C12 PF01088.21 KND93098.1 - 6.6e-45 153.4 0.0 2.9e-44 151.3 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF445 PF04286.12 KND93098.1 - 0.072 12.9 1.8 0.12 12.1 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2877 PF11392.8 KND93098.1 - 0.4 11.4 1.9 20 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2877) Transglut_core2 PF13369.6 KND93099.1 - 6.6e-20 71.2 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 KND93099.1 - 7.4e-13 48.8 0.0 1.7e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 KND93099.1 - 1.9e-06 27.6 1.2 4.4e-06 26.5 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND93099.1 - 3.6e-05 23.5 1.0 6.8e-05 22.6 1.0 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_C14 PF00656.22 KND93100.1 - 1.8e-64 218.1 0.0 2.5e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Cnn_1N PF07989.11 KND93103.1 - 8.9e-27 93.1 3.0 8.9e-27 93.1 3.0 14.9 7 4 6 13 13 13 4 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KND93103.1 - 1.2e-12 48.2 15.8 4.9e-07 30.2 0.1 5.9 3 1 1 4 4 4 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 KND93103.1 - 0.0074 16.3 1.8 0.0074 16.3 1.8 12.7 6 4 6 13 13 13 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.6 KND93103.1 - 0.0078 16.6 13.5 0.0078 16.6 13.5 12.2 5 3 6 12 12 12 2 Domain of unknown function (DUF4200) Spc7 PF08317.11 KND93103.1 - 0.18 10.7 188.4 0.0067 15.4 14.6 9.5 1 1 7 9 9 9 0 Spc7 kinetochore protein Acetyltransf_7 PF13508.7 KND93104.1 - 5e-06 26.9 0.0 7.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND93104.1 - 0.00011 22.4 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND93104.1 - 0.00094 19.1 0.1 0.0024 17.8 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FMO-like PF00743.19 KND93105.1 - 6.2e-47 160.2 0.0 1.7e-37 129.0 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND93105.1 - 4.3e-13 49.2 0.0 7.7e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND93105.1 - 2e-12 47.0 0.0 5e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND93105.1 - 2.6e-06 27.5 0.1 0.0098 15.9 0.0 3.4 4 1 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND93105.1 - 3.6e-06 26.4 0.0 4.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) RNase_T PF00929.24 KND93105.1 - 0.00049 20.7 0.0 0.019 15.5 0.0 2.3 2 0 0 2 2 2 1 Exonuclease DAO PF01266.24 KND93105.1 - 0.00069 19.3 0.0 3.6 7.1 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND93105.1 - 0.039 14.2 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2457 PF10446.9 KND93105.1 - 0.089 11.9 1.9 0.14 11.3 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) APH PF01636.23 KND93106.1 - 0.025 14.5 0.4 0.028 14.3 0.4 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Profilin PF00235.19 KND93107.1 - 2.9e-44 150.4 0.9 3.5e-44 150.1 0.9 1.1 1 0 0 1 1 1 1 Profilin Synaptobrevin PF00957.21 KND93109.1 - 1.7e-14 53.4 0.7 2.5e-14 52.8 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KND93109.1 - 3.6e-13 49.4 0.0 7e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec63 PF02889.16 KND93110.1 - 1.1e-133 444.1 0.0 1.1e-79 267.2 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KND93110.1 - 7.2e-50 169.2 0.1 8.4e-26 90.8 0.3 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 KND93110.1 - 4.6e-22 78.8 0.0 4e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND93110.1 - 1.4e-15 57.6 0.4 2e-06 28.1 0.0 4.5 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KND93110.1 - 2e-08 34.6 0.3 0.0011 19.3 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KND93110.1 - 1.1e-05 25.8 0.4 0.0054 17.1 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KND93110.1 - 0.00032 21.1 0.1 1.5 9.2 0.0 4.3 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KND93110.1 - 0.013 14.6 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 KND93110.1 - 0.11 12.3 0.3 17 5.1 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein Helicase_PWI PF18149.1 KND93110.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 N-terminal helicase PWI domain Actin PF00022.19 KND93111.1 - 3.1e-53 180.9 0.0 4.8e-51 173.7 0.0 2.3 1 1 0 1 1 1 1 Actin DASH_Dad4 PF08650.10 KND93112.1 - 4.7e-19 68.1 2.9 6.4e-19 67.7 2.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF5545 PF17699.1 KND93112.1 - 0.06 13.2 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5545) YL1_C PF08265.11 KND93113.1 - 5.8e-15 54.7 0.1 9.8e-15 54.0 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pterin_4a PF01329.19 KND93114.1 - 1.1e-24 86.4 0.1 1.4e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase bZIP_1 PF00170.21 KND93115.1 - 4.6e-08 33.0 9.4 2.6e-07 30.6 9.4 2.1 1 1 0 1 1 1 1 bZIP transcription factor Leu_zip PF15294.6 KND93115.1 - 0.016 14.7 0.2 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 Leucine zipper U1snRNP70_N PF12220.8 KND93115.1 - 0.093 13.4 4.2 6.8 7.4 1.3 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF501 PF04417.12 KND93115.1 - 0.16 11.7 0.6 0.38 10.6 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Ribosomal_L30_N PF08079.12 KND93115.1 - 0.7 10.2 12.4 1.7 9.0 12.4 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PRKG1_interact PF15898.5 KND93115.1 - 6.2 7.8 11.5 0.43 11.5 2.3 2.8 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain MFS_1 PF07690.16 KND93116.1 - 1.8e-23 83.1 40.2 1.5e-16 60.3 24.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily HIT PF01230.23 KND93116.1 - 2.4e-17 63.5 0.0 4.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain PUCC PF03209.15 KND93116.1 - 0.00082 18.5 6.9 0.04 12.9 5.8 2.3 2 0 0 2 2 2 2 PUCC protein DUF5326 PF17260.2 KND93116.1 - 0.034 14.3 0.8 0.034 14.3 0.8 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5326) OATP PF03137.20 KND93116.1 - 0.68 8.1 6.5 0.22 9.8 1.8 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Golgin_A5 PF09787.9 KND93117.1 - 0.00027 20.5 0.5 0.0003 20.4 0.5 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF2959 PF11172.8 KND93117.1 - 0.0086 16.2 0.7 0.012 15.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Tropomyosin_1 PF12718.7 KND93117.1 - 0.0088 16.2 1.5 0.01 16.0 1.5 1.1 1 0 0 1 1 1 1 Tropomyosin like HisKA_3 PF07730.13 KND93117.1 - 0.037 14.5 1.0 7.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase Seryl_tRNA_N PF02403.22 KND93117.1 - 0.077 13.2 0.7 0.11 12.8 0.6 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 KND93117.1 - 0.13 12.4 3.7 0.2 11.8 3.7 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 KND93117.1 - 0.14 11.8 3.2 4.3 6.9 0.4 2.0 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HalX PF08663.10 KND93117.1 - 3.5 8.0 8.6 1.9 8.9 2.0 2.4 1 1 0 2 2 2 0 HalX domain Myb_Cef PF11831.8 KND93118.1 - 2.5e-52 177.8 9.1 2.5e-52 177.8 9.1 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KND93118.1 - 3.7e-21 75.1 5.7 7.2e-11 42.1 0.9 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND93118.1 - 1.5e-19 70.0 9.3 7.1e-15 55.0 2.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KND93118.1 - 0.0071 16.4 1.3 0.092 12.9 0.0 3.1 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DcpS PF05652.12 KND93119.1 - 8.1e-34 116.6 0.0 1.2e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KND93119.1 - 6.5e-33 113.6 0.0 9.2e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding MFS_1 PF07690.16 KND93120.1 - 5.3e-41 140.7 47.0 5.3e-41 140.7 47.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93120.1 - 2.5e-11 43.1 12.5 2.5e-11 43.1 12.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KND93120.1 - 0.00025 19.6 12.8 0.00025 19.6 12.8 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) SH3_9 PF14604.6 KND93121.1 - 4.7e-05 23.2 0.2 9.4e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain Glycophorin_A PF01102.18 KND93121.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A SH3_1 PF00018.28 KND93121.1 - 0.0002 20.9 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Mid2 PF04478.12 KND93121.1 - 0.03 14.2 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4690 PF15756.5 KND93121.1 - 0.03 14.9 1.4 0.082 13.5 0.1 2.4 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 KND93121.1 - 0.037 14.1 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 KND93121.1 - 0.038 13.9 1.1 0.075 13.0 1.1 1.4 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 KND93121.1 - 0.072 13.5 0.1 0.072 13.5 0.1 1.8 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF5518 PF17647.1 KND93121.1 - 0.78 9.9 12.3 1.3 9.2 3.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5518) GILT PF03227.16 KND93122.1 - 1.9e-18 66.7 0.0 3.7e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Got1 PF04178.12 KND93123.1 - 2.8e-14 53.5 13.2 3.7e-14 53.1 13.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family End3 PF12761.7 KND93124.1 - 1.9e-77 260.0 3.1 2.6e-77 259.5 3.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KND93124.1 - 3.5e-46 155.4 0.0 1.1e-45 153.9 0.0 1.9 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KND93124.1 - 4.6e-06 25.8 0.1 1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KND93124.1 - 5e-05 23.7 0.4 0.00025 21.4 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KND93124.1 - 0.0042 16.9 0.1 0.024 14.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 KND93124.1 - 0.0098 15.7 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 KND93124.1 - 0.024 14.1 0.2 0.068 12.7 0.2 1.8 1 0 0 1 1 1 0 EF hand NPV_P10 PF05531.12 KND93124.1 - 0.12 12.9 0.4 16 6.1 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 KND93124.1 - 0.66 10.1 3.3 0.46 10.6 0.3 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM NUDIX PF00293.28 KND93125.1 - 6.1e-27 94.2 0.0 9.1e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.7 KND93126.1 - 6.2e-07 29.7 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND93126.1 - 2e-06 28.0 0.0 3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KND93126.1 - 1.2e-05 25.4 0.1 2.7e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KND93126.1 - 9.2e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND93126.1 - 0.00046 20.1 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND93126.1 - 0.0033 17.5 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RPA_C PF08784.11 KND93127.1 - 7.3e-21 74.8 0.4 1.7e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KND93127.1 - 4.5e-09 36.2 0.1 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DUF4766 PF15973.5 KND93127.1 - 3.1 8.4 15.2 0.81 10.3 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Zn_clus PF00172.18 KND93128.1 - 0.47 10.6 5.7 0.4 10.8 0.9 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mlh1_C PF16413.5 KND93129.1 - 2.5e-100 335.3 0.0 4e-100 334.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KND93129.1 - 1e-34 118.7 0.1 1.6e-34 118.1 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KND93129.1 - 1.6e-12 47.5 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KND93129.1 - 3.8e-06 27.4 0.0 9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FHA PF00498.26 KND93130.1 - 3.8e-09 36.8 0.4 5.4e-09 36.3 0.4 1.4 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND93130.1 - 2.8e-05 24.4 0.0 3.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 KND93131.1 - 2e-13 50.3 0.0 2.8e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93131.1 - 2.3e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C2H2_4 PF13894.6 KND93132.1 - 1.2e-12 47.5 28.0 0.012 16.4 0.3 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND93132.1 - 2.2e-11 43.7 25.5 7.1e-05 23.0 3.4 6.0 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KND93132.1 - 7.5e-10 38.6 24.4 0.0072 16.3 1.5 6.7 6 1 0 6 6 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 KND93132.1 - 2.6e-08 33.9 32.7 0.0091 16.4 0.2 7.5 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-met PF12874.7 KND93132.1 - 5.9e-08 32.8 24.7 0.012 16.0 2.1 6.1 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KND93132.1 - 1e-07 32.2 21.9 0.086 13.2 0.5 6.2 2 2 4 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KND93132.1 - 2.2e-07 31.0 26.6 1.2 9.7 0.6 6.5 6 0 0 6 6 6 4 Zinc-finger double domain Trm112p PF03966.16 KND93132.1 - 0.017 15.7 3.8 7.2 7.3 0.0 3.6 2 1 0 2 2 2 0 Trm112p-like protein HypA PF01155.19 KND93132.1 - 0.029 14.4 9.4 0.39 10.7 1.2 3.5 2 2 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Di19 PF05605.12 KND93132.1 - 0.039 14.3 0.0 0.039 14.3 0.0 4.9 3 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KND93132.1 - 0.05 13.5 11.2 3 7.9 0.4 4.8 4 0 0 4 4 4 0 zinc-finger of a C2HC-type RIG-I_C-RD PF11648.8 KND93132.1 - 0.099 12.9 1.1 0.26 11.5 1.1 1.7 1 0 0 1 1 1 0 C-terminal domain of RIG-I Baculo_IE-1 PF05290.11 KND93132.1 - 0.1 12.5 5.4 0.63 10.0 0.4 2.8 3 1 1 4 4 4 0 Baculovirus immediate-early protein (IE-0) zf_ZIC PF18366.1 KND93132.1 - 0.24 11.6 7.8 5.1 7.3 0.0 4.5 3 1 2 5 5 5 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 KND93132.1 - 0.76 10.3 18.6 5.4 7.5 0.4 5.5 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-RRPl_C4 PF17026.5 KND93132.1 - 2.4 8.3 10.6 0.16 12.1 1.2 3.0 2 1 1 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-RING_7 PF02591.15 KND93132.1 - 7.1 6.9 7.6 5.6 7.2 0.1 3.5 4 0 0 4 4 2 0 C4-type zinc ribbon domain AKAP95 PF04988.12 KND93132.1 - 8.4 6.6 9.9 4.2 7.6 1.4 3.3 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF5596 PF18082.1 KND93133.1 - 0.069 13.0 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) SPX PF03105.19 KND93134.1 - 0.49 10.2 33.4 13 5.6 0.0 2.1 1 1 1 2 2 2 0 SPX domain Pkinase PF00069.25 KND93135.1 - 2.2e-17 63.3 0.0 2.2e-11 43.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND93135.1 - 6.2e-06 25.7 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KND93135.1 - 0.0082 15.5 0.0 0.38 10.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like EB1 PF03271.17 KND93136.1 - 2.7e-16 59.5 2.8 5.5e-16 58.5 2.8 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KND93136.1 - 1.3e-06 28.6 0.6 2.5e-06 27.6 0.6 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 KND93136.1 - 0.014 15.5 0.2 0.025 14.7 0.2 1.5 1 1 0 1 1 1 0 CH-like domain in sperm protein PepSY_like PF11396.8 KND93136.1 - 0.079 13.5 0.1 0.39 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like Suppressor_APC PF11414.8 KND93136.1 - 0.084 12.9 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Syja_N PF02383.18 KND93136.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain PX PF00787.24 KND93137.1 - 1.5e-14 53.9 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Orbi_VP5 PF00901.17 KND93137.1 - 0.084 11.3 0.0 0.15 10.4 0.0 1.4 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF16 PF01519.16 KND93137.1 - 1.7 9.2 8.4 2.2 8.8 7.2 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 adh_short_C2 PF13561.6 KND93138.1 - 2.1e-55 187.8 0.5 2.7e-55 187.5 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND93138.1 - 3.9e-48 163.5 0.3 4.8e-48 163.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND93138.1 - 1.6e-12 47.7 0.4 5.2e-12 46.0 0.4 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KND93138.1 - 0.00052 19.5 0.2 0.0028 17.2 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND93138.1 - 0.043 12.9 0.1 0.089 11.9 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Ribosomal_S11 PF00411.19 KND93138.1 - 0.078 13.4 0.2 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S11 AdoHcyase_NAD PF00670.21 KND93138.1 - 0.11 12.6 0.9 0.26 11.4 0.9 1.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TLP1_add_C PF18313.1 KND93138.1 - 0.14 12.1 0.2 0.47 10.4 0.1 1.9 2 0 0 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain DEAD PF00270.29 KND93139.1 - 3.3e-48 163.8 0.0 6.5e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2183 PF09949.9 KND93139.1 - 1.4e-30 105.5 0.0 3.4e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Helicase_C PF00271.31 KND93139.1 - 2.2e-27 95.6 0.1 8.9e-27 93.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KND93139.1 - 0.18 10.5 0.6 0.57 8.9 0.1 2.1 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Lon_C PF05362.13 KND93140.1 - 1.5e-66 223.8 0.7 2.9e-66 222.9 0.7 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KND93140.1 - 1.3e-23 84.0 0.0 2.4e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KND93140.1 - 1.4e-22 80.5 0.0 3.6e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KND93140.1 - 3e-08 33.8 0.0 7.7e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KND93140.1 - 2.7e-06 27.3 0.1 2.3e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 KND93140.1 - 8.1e-06 26.3 0.0 3.3e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KND93140.1 - 1.6e-05 25.1 0.0 4.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 KND93140.1 - 2.9e-05 23.9 0.0 9.5e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KND93140.1 - 0.00013 21.7 0.0 0.00039 20.2 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 KND93140.1 - 0.00015 22.1 0.0 0.01 16.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KND93140.1 - 0.00022 21.0 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KND93140.1 - 0.004 16.4 0.1 0.01 15.1 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KND93140.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KND93140.1 - 0.018 15.5 0.2 0.22 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KND93140.1 - 0.021 14.8 0.1 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SOAR PF16533.5 KND93140.1 - 0.025 14.6 0.2 0.063 13.3 0.2 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region RNA_helicase PF00910.22 KND93140.1 - 0.03 14.7 0.0 0.087 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KND93140.1 - 0.046 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND93140.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 KND93140.1 - 0.065 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.21 KND93140.1 - 0.075 12.4 0.2 0.17 11.2 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KND93140.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 KND93140.1 - 0.088 12.4 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KND93140.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND93140.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 KND93140.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND93140.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 KND93140.1 - 0.16 12.4 0.9 0.91 9.9 0.1 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KND93140.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Arm PF00514.23 KND93142.1 - 0.084 13.0 3.5 5.2 7.3 0.1 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KND93142.1 - 0.23 11.8 3.9 0.96 9.9 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Astro_capsid_p PF12226.8 KND93142.1 - 2.2 7.4 7.9 0.97 8.5 5.5 1.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF3112 PF11309.8 KND93144.1 - 3.5e-10 39.7 5.6 3.8e-08 33.0 0.8 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) DUF4234 PF14018.6 KND93144.1 - 0.23 11.6 2.6 2.6 8.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) MIG-14_Wnt-bd PF06664.12 KND93144.1 - 0.38 9.9 9.9 0.79 8.9 9.9 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Metallophos PF00149.28 KND93145.1 - 9.4e-36 124.2 0.8 1.4e-35 123.6 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KND93145.1 - 0.025 15.0 0.1 0.051 14.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Wyosine_form PF08608.12 KND93146.1 - 3.8e-25 88.0 0.0 7.8e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KND93146.1 - 1.7e-24 87.0 0.1 6.9e-24 85.1 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 KND93146.1 - 1.9e-09 37.9 0.1 1.2e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin Exo84_C PF16528.5 KND93147.1 - 1.9e-76 256.5 0.1 1.9e-76 256.5 0.1 2.3 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KND93147.1 - 3.4e-12 46.3 0.2 3.4e-12 46.3 0.2 2.2 3 0 0 3 3 3 1 Vps51/Vps67 HMMR_C PF15908.5 KND93147.1 - 0.013 15.7 0.8 0.013 15.7 0.8 2.5 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DUF2383 PF09537.10 KND93147.1 - 0.11 12.9 2.4 0.23 11.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) MAS20 PF02064.15 KND93148.1 - 2.8e-33 114.8 5.1 2e-31 108.8 5.1 2.1 1 1 0 1 1 1 1 MAS20 protein import receptor Rhabdo_ncap PF00945.18 KND93148.1 - 0.22 10.3 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Glyco_hydro_47 PF01532.20 KND93149.1 - 9.1e-166 552.3 0.0 1.1e-165 551.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 KND93150.1 - 8.9e-58 195.7 0.0 1.4e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93150.1 - 6.1e-44 150.2 0.0 9.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93150.1 - 1.4e-07 31.1 0.0 2.4e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KND93150.1 - 0.002 17.5 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND93150.1 - 0.0099 14.7 0.0 0.025 13.4 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KND93150.1 - 0.063 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 KND93151.1 - 2.9e-50 168.2 3.7 8.9e-19 67.2 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 KND93152.1 - 6.3e-170 566.3 0.0 9.7e-170 565.7 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family RasGAP_C PF03836.15 KND93152.1 - 0.016 15.4 0.2 0.042 14.0 0.2 1.7 1 0 0 1 1 1 0 RasGAP C-terminus DHR10 PF18595.1 KND93152.1 - 0.018 15.1 3.9 0.03 14.4 1.8 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4164 PF13747.6 KND93152.1 - 0.056 13.7 9.8 0.078 13.3 5.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) LRV PF01816.17 KND93152.1 - 0.058 13.8 0.2 0.3 11.5 0.2 2.3 1 0 0 1 1 1 0 Leucine rich repeat variant FliD_C PF07195.12 KND93152.1 - 0.087 12.2 0.9 0.16 11.4 0.9 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4527 PF15030.6 KND93152.1 - 0.24 10.8 6.7 0.025 14.0 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Trimer_CC PF08954.11 KND93152.1 - 0.3 10.7 3.3 0.41 10.2 0.1 2.8 3 0 0 3 3 3 0 Trimerisation motif Orthopox_A5L PF06193.11 KND93152.1 - 0.34 10.3 2.6 0.55 9.6 2.6 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like DUF4407 PF14362.6 KND93152.1 - 0.37 10.1 3.9 0.79 9.0 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 KND93152.1 - 0.46 10.8 3.7 1 9.7 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4763 PF15960.5 KND93152.1 - 0.59 9.4 3.9 0.97 8.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF1664 PF07889.12 KND93152.1 - 1.1 9.4 3.8 1.2 9.2 2.1 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) COG2 PF06148.11 KND93152.1 - 1.1 9.4 5.8 4.1 7.5 1.3 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YscO PF07321.12 KND93152.1 - 2.6 8.0 9.9 0.47 10.4 3.9 2.4 1 1 1 2 2 2 0 Type III secretion protein YscO Baculo_PEP_C PF04513.12 KND93152.1 - 3.1 7.8 7.2 3.2 7.8 3.6 2.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 KND93152.1 - 4.8 7.5 8.8 18 5.7 8.8 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 KND93152.1 - 7.3 6.7 13.2 0.03 14.4 2.5 2.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein GFA PF04828.14 KND93153.1 - 3.3e-09 37.0 8.2 3.8e-06 27.1 0.0 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KND93153.1 - 0.039 13.6 0.2 0.039 13.6 0.2 3.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.6 KND93153.1 - 0.05 13.5 0.2 0.05 13.5 0.2 3.3 4 0 0 4 4 4 0 Nudix N-terminal Rsm1 PF08600.10 KND93153.1 - 0.18 12.0 1.2 5.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Rsm1-like ANAPC4_WD40 PF12894.7 KND93154.1 - 0.00022 21.5 0.0 0.3 11.4 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND93154.1 - 0.029 15.2 0.7 8.7 7.4 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat PucR PF07905.11 KND93155.1 - 0.049 13.9 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Hpt PF01627.23 KND93155.1 - 0.08 13.2 0.1 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Hpt domain GFO_IDH_MocA PF01408.22 KND93156.1 - 6.7e-10 39.8 0.2 9.8e-10 39.3 0.1 1.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fructosamin_kin PF03881.14 KND93158.1 - 4.9e-08 32.5 0.0 5.9e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase CoA_binding_2 PF13380.6 KND93159.1 - 5.4e-20 72.0 0.0 8.2e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 CoA binding domain PAAR_motif PF05488.13 KND93159.1 - 0.083 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 PAAR motif CIMR PF00878.18 KND93161.1 - 9.4e-07 29.0 0.2 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 KND93161.1 - 2.8e-05 24.1 0.0 6.9e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KND93161.1 - 2.9e-05 23.3 0.0 6.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Myb_DNA-bind_4 PF13837.6 KND93162.1 - 0.00051 20.4 0.1 0.00093 19.5 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 KND93162.1 - 0.056 13.7 0.4 1.3 9.2 1.1 2.6 2 1 0 2 2 2 0 Myb-like DNA-binding domain Scs3p PF10261.9 KND93163.1 - 5.7e-76 255.3 4.1 7.6e-76 254.9 4.1 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.9 KND93163.1 - 1.2e-21 76.6 0.1 2.4e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase AAA_16 PF13191.6 KND93164.1 - 2.4e-07 31.3 0.0 2.9e-06 27.8 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain Ank PF00023.30 KND93164.1 - 3.7e-05 24.0 0.0 0.065 13.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.12 KND93164.1 - 6.3e-05 22.9 0.0 0.00021 21.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 KND93164.1 - 7e-05 23.3 0.0 0.093 13.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND93164.1 - 0.00025 21.6 0.1 0.12 12.9 0.0 3.5 2 2 1 3 3 3 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 KND93164.1 - 0.0022 18.3 0.1 0.0081 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 KND93164.1 - 0.0029 17.9 0.0 0.28 11.6 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93164.1 - 0.0035 17.7 0.1 2.8 8.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat AAA PF00004.29 KND93164.1 - 0.007 16.8 0.1 0.059 13.8 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Glyco_hydro_3_C PF01915.22 KND93167.1 - 4.5e-41 141.1 0.0 8.5e-41 140.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KND93167.1 - 1.8e-36 126.1 0.0 3e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KND93167.1 - 7.5e-18 64.4 0.4 1.6e-17 63.3 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.17 KND93168.1 - 7.7e-163 542.2 0.6 8.8e-163 542.0 0.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Ist1 PF03398.14 KND93169.1 - 1.4e-60 204.0 1.4 1.7e-60 203.7 1.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_4 PF14392.6 KND93170.1 - 0.7 9.7 7.4 5.1 6.9 2.0 2.4 2 0 0 2 2 2 0 Zinc knuckle DTHCT PF08070.11 KND93171.1 - 4.8 8.0 12.6 76 4.1 1.2 3.1 1 1 1 2 2 2 0 DTHCT (NUC029) region PDZ_1 PF12812.7 KND93172.1 - 1.4e-57 191.6 0.1 7.3e-37 125.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KND93172.1 - 9.3e-20 72.1 1.7 4.6e-17 63.3 0.4 2.6 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 KND93172.1 - 4.3e-14 52.6 0.3 1e-06 29.0 0.0 4.4 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 KND93172.1 - 2.3e-13 49.8 0.1 4.1e-05 23.3 0.1 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 KND93172.1 - 4e-09 36.7 0.0 0.00036 20.8 0.0 3.9 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 KND93172.1 - 0.001 19.0 1.2 0.23 11.4 0.2 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KND93172.1 - 0.0084 15.8 0.1 0.028 14.1 0.1 2.0 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Trypsin PF00089.26 KND93172.1 - 0.021 14.7 0.6 0.14 11.9 0.6 2.2 1 1 0 1 1 1 0 Trypsin Peptidase_S46 PF10459.9 KND93172.1 - 0.031 12.9 0.3 0.21 10.2 0.1 1.9 2 0 0 2 2 2 0 Peptidase S46 CUE PF02845.16 KND93173.1 - 3.4e-10 39.4 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 KND93173.1 - 0.25 11.4 1.5 0.42 10.7 1.5 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 DnaJ PF00226.31 KND93174.1 - 1.6e-20 73.0 0.6 3e-20 72.1 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.19 KND93175.1 - 1.6e-45 154.9 0.3 2.1e-45 154.5 0.3 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KND93175.1 - 1.6e-05 24.9 0.3 0.17 11.8 0.1 2.7 2 1 1 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 KND93175.1 - 0.00011 22.8 0.1 0.00019 22.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KND93175.1 - 0.0029 16.6 1.3 2.1 7.3 0.1 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KND93175.1 - 0.0046 16.7 0.1 0.073 12.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 KND93175.1 - 0.0083 16.0 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KND93175.1 - 0.0098 15.4 0.1 3.4 7.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KND93175.1 - 0.033 13.9 1.1 0.1 12.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 KND93175.1 - 0.037 13.8 0.8 4.5 7.0 0.3 2.3 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KND93175.1 - 0.057 13.5 0.3 0.24 11.5 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KND93175.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KND93175.1 - 0.065 13.5 0.3 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KND93175.1 - 0.1 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KND93175.1 - 0.1 12.0 0.3 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 KND93175.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KND93175.1 - 0.15 12.6 0.1 0.44 11.0 0.1 1.8 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KND93175.1 - 0.19 10.7 1.2 0.27 10.2 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NOT2_3_5 PF04153.18 KND93176.1 - 2.4e-30 105.3 2.2 4.4e-30 104.4 2.2 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Fungal_trans_2 PF11951.8 KND93177.1 - 3.2e-10 39.4 0.9 1e-09 37.7 0.2 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Mob1_phocein PF03637.17 KND93178.1 - 3.6e-23 82.4 0.2 5.3e-23 81.9 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KND93178.1 - 0.19 12.0 1.9 0.38 11.1 1.9 1.4 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Ank_2 PF12796.7 KND93179.1 - 4.1e-12 46.5 0.0 5.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND93179.1 - 8.4e-12 45.4 0.2 1.3e-05 25.6 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 KND93179.1 - 1.4e-11 44.3 0.2 8.4e-09 35.5 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KND93179.1 - 7.3e-11 42.1 0.1 3.4e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93179.1 - 4.6e-10 38.9 0.0 9e-07 28.7 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat XFP_N PF09364.10 KND93180.1 - 4.6e-166 552.1 0.0 6.2e-166 551.7 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 KND93180.1 - 9.8e-81 269.7 0.0 1.6e-80 269.0 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 KND93180.1 - 7e-79 264.0 0.0 9.8e-79 263.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Ribosomal_S2 PF00318.20 KND93181.1 - 8.7e-63 211.4 2.7 4.2e-62 209.2 0.2 2.6 2 1 0 2 2 2 1 Ribosomal protein S2 CBS PF00571.28 KND93181.1 - 9.8e-32 109.2 8.3 1.5e-07 31.7 0.0 5.8 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 KND93181.1 - 1.7e-07 31.1 0.2 6e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 PB1 domain zf-H2C2 PF09337.10 KND93182.1 - 5e-15 55.4 2.0 9.9e-15 54.5 2.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KND93182.1 - 1.2e-10 41.3 0.1 1.2e-10 41.3 0.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KND93182.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KND93182.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND93182.1 - 0.094 13.4 0.0 0.21 12.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.24 KND93183.1 - 8.7e-154 512.8 6.2 1e-153 512.6 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 KND93183.1 - 0.1 13.1 0.1 0.48 10.9 0.0 2.2 3 0 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 KND93183.1 - 0.53 10.7 2.0 1.2 9.5 2.1 2.0 1 1 0 1 1 1 0 Cell division protein FtsA AAA_33 PF13671.6 KND93184.1 - 0.12 12.5 2.9 0.2 11.8 0.3 2.2 2 1 1 3 3 3 0 AAA domain PDCD2_C PF04194.13 KND93185.1 - 3.4e-43 147.7 0.0 3.8e-42 144.3 0.0 2.3 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zinc_ribbon_4 PF13717.6 KND93185.1 - 0.16 11.9 0.8 12 5.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Cpn60_TCP1 PF00118.24 KND93186.1 - 1e-161 538.9 0.6 1.1e-161 538.8 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KND93186.1 - 0.021 13.3 0.0 0.031 12.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4470 PF14737.6 KND93187.1 - 1.5e-11 44.3 1.1 1.7e-08 34.5 1.1 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KND93187.1 - 2e-10 40.6 15.5 4.2e-10 39.5 15.5 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KND93187.1 - 6.9 7.1 11.0 19 5.6 11.0 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2H2 PF00096.26 KND93188.1 - 6.4e-10 38.9 18.7 0.00041 20.6 7.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND93188.1 - 8.3e-07 29.2 12.5 0.0038 17.6 3.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND93188.1 - 8e-05 23.2 17.2 0.2 12.6 6.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KND93188.1 - 0.066 13.0 7.9 0.67 9.8 2.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KND93188.1 - 0.83 9.7 9.4 8.4 6.5 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.19 KND93188.1 - 1.5 8.9 5.2 4.5 7.5 5.2 1.8 1 0 0 1 1 1 0 AT hook motif MOSC PF03473.17 KND93189.1 - 2.7e-11 43.6 0.0 4.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KND93189.1 - 1.6e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SHR3_chaperone PF08229.11 KND93189.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 SMC_N PF02463.19 KND93190.1 - 1.8e-67 227.0 8.7 3.3e-36 124.8 0.6 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND93190.1 - 2.4e-20 73.0 0.4 2.4e-20 73.0 0.4 3.1 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KND93190.1 - 4.1e-08 33.4 9.6 0.0027 17.5 0.2 3.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND93190.1 - 0.001 18.7 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 KND93190.1 - 0.0042 16.7 19.8 0.0042 16.7 19.8 6.3 3 2 2 5 5 5 2 Mechanosensitive ion channel porin domain Tup_N PF08581.10 KND93190.1 - 0.0052 17.1 2.7 0.0052 17.1 2.7 7.7 4 3 4 8 8 8 1 Tup N-terminal COG2 PF06148.11 KND93190.1 - 0.012 15.7 2.4 0.012 15.7 2.4 7.7 5 2 3 8 8 8 0 COG (conserved oligomeric Golgi) complex component, COG2 HSBP1 PF06825.12 KND93190.1 - 0.11 12.3 10.7 0.26 11.2 0.3 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2316 PF10078.9 KND93190.1 - 8.5 6.7 9.2 1.4 9.2 1.4 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) ABC_tran PF00005.27 KND93190.1 - 9.8 6.7 27.4 1.6 9.2 0.1 5.7 3 2 0 3 3 3 0 ABC transporter WD40 PF00400.32 KND93191.1 - 2.3e-16 59.9 14.8 0.0011 19.8 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND93191.1 - 0.00029 21.1 0.1 1.7 9.0 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND93191.1 - 0.094 11.3 0.9 0.3 9.7 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ccdc124 PF06244.12 KND93192.1 - 3.5e-30 105.2 6.3 3.5e-30 105.2 6.3 2.5 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 SbsC_C PF18058.1 KND93192.1 - 0.043 14.0 0.6 0.043 14.0 0.6 2.4 2 1 1 3 3 3 0 SbsC C-terminal domain DUF3235 PF11574.8 KND93192.1 - 0.72 10.7 0.0 0.72 10.7 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3235) Rieske PF00355.26 KND93193.1 - 8.6e-11 41.6 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 KND93193.1 - 3.3e-10 40.3 0.8 3.3e-10 40.3 0.8 2.0 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region MMS1_N PF10433.9 KND93194.1 - 7.8e-117 390.9 0.0 1.2e-116 390.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KND93194.1 - 4.7e-62 210.2 0.0 1.5e-61 208.5 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Peptidase_C1 PF00112.23 KND93195.1 - 0.00053 20.1 0.3 0.0014 18.7 0.1 1.7 2 0 0 2 2 2 1 Papain family cysteine protease PQ-loop PF04193.14 KND93196.1 - 6.1e-22 77.1 14.3 5.1e-13 48.6 0.5 3.1 3 1 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KND93196.1 - 0.00084 20.2 2.5 0.01 16.7 0.6 2.2 2 0 0 2 2 2 1 ER lumen protein retaining receptor Wzy_C PF04932.15 KND93196.1 - 0.018 14.7 2.3 0.37 10.4 0.4 2.9 2 1 0 2 2 2 0 O-Antigen ligase CrgA PF06781.12 KND93196.1 - 2.2 8.4 11.0 0.24 11.5 1.7 3.4 2 1 1 4 4 4 0 Cell division protein CrgA R3H-assoc PF13902.6 KND93198.1 - 2.3e-22 79.8 3.5 2.3e-22 79.8 3.5 1.6 2 0 0 2 2 2 1 R3H-associated N-terminal domain Apt1 PF10351.9 KND93199.1 - 1 8.1 4.0 1.2 7.9 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRCC PF10253.9 KND93199.1 - 1.1 10.0 8.7 1.4 9.6 8.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting QWRF PF04484.12 KND93199.1 - 6.3 6.4 12.5 8.6 6.0 12.5 1.1 1 0 0 1 1 1 0 QWRF family SOG2 PF10428.9 KND93199.1 - 7.8 5.6 20.9 11 5.1 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FA_desaturase PF00487.24 KND93200.1 - 1.2e-17 64.6 11.5 1.2e-17 64.6 11.5 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 KND93200.1 - 2.5e-17 62.8 0.1 8.4e-17 61.1 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain SKG6 PF08693.10 KND93202.1 - 0.02 14.3 0.1 0.041 13.3 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KND93202.1 - 0.072 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 KND93202.1 - 0.073 13.3 0.0 8.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) GTP_EFTU PF00009.27 KND93203.1 - 1.5e-49 168.2 0.0 2.9e-49 167.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KND93203.1 - 5e-20 71.4 0.0 1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KND93203.1 - 3.4e-13 49.4 0.0 2.3e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KND93203.1 - 0.00019 21.8 0.0 0.00053 20.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KND93203.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain COPI_assoc PF08507.10 KND93204.1 - 5.8e-25 87.8 5.3 7.7e-25 87.4 5.3 1.1 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 KND93204.1 - 0.24 10.8 0.2 0.24 10.8 0.2 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cg6151-P PF10233.9 KND93204.1 - 0.27 11.6 7.9 0.57 10.5 7.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF4225 PF13988.6 KND93204.1 - 6.1 6.4 6.0 0.39 10.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) NMD3 PF04981.13 KND93205.1 - 1.7e-75 253.7 4.1 2.5e-75 253.1 4.1 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KND93205.1 - 3.3 7.8 9.8 6e+02 0.6 9.9 2.8 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 KND93206.1 - 7.1e-06 25.8 0.0 0.00086 19.1 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldedh PF00171.22 KND93207.1 - 6.8e-131 437.0 0.0 7.6e-131 436.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KND93207.1 - 0.0027 16.8 0.0 0.0044 16.1 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) CN_hydrolase PF00795.22 KND93209.1 - 2e-27 96.2 0.0 2.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KND93209.1 - 9.7e-16 57.6 0.2 3.8e-15 55.7 0.2 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 KND93209.1 - 0.041 13.6 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Syntaxin-18_N PF10496.9 KND93210.1 - 4.5e-09 36.4 0.0 5.5e-08 32.9 0.0 2.7 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KND93210.1 - 0.026 14.5 0.0 0.075 13.0 0.0 1.8 1 0 0 1 1 1 0 SNARE domain Beach PF02138.18 KND93210.1 - 0.18 11.1 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 Beige/BEACH domain Aminotran_1_2 PF00155.21 KND93211.1 - 7.8e-82 275.3 0.0 1e-81 275.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NICE-1 PF15845.5 KND93211.1 - 2 9.2 5.3 3.9 8.3 5.3 1.4 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family DEC-1_N PF04625.13 KND93211.1 - 2.9 6.8 7.5 4.3 6.2 7.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF908 PF06012.12 KND93212.1 - 6.7 6.0 16.5 0.069 12.6 3.6 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Methyltransf_25 PF13649.6 KND93215.1 - 4.8e-08 33.6 0.0 1.7e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND93215.1 - 2.1e-06 27.7 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KND93215.1 - 0.00025 20.9 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KND93215.1 - 0.001 19.8 0.0 0.0048 17.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 KND93215.1 - 0.0023 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 KND93215.1 - 0.0046 17.6 0.0 0.013 16.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KND93215.1 - 0.0089 15.6 0.0 0.081 12.5 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 KND93215.1 - 0.0096 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KND93215.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.5 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 KND93215.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.7 1 1 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 KND93215.1 - 0.076 14.1 0.0 0.56 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Mpv17_PMP22 PF04117.12 KND93215.1 - 0.14 12.4 0.1 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Mpv17 / PMP22 family Ubie_methyltran PF01209.18 KND93215.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Amidase PF01425.21 KND93216.1 - 1.1e-88 298.2 0.1 1.8e-88 297.5 0.1 1.3 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 KND93216.1 - 9.4e-86 287.7 0.0 1.7e-85 286.8 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KND93216.1 - 1.2e-62 211.1 0.0 2.2e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KND93216.1 - 2.9e-39 134.0 0.2 1.5e-38 131.7 0.1 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 KND93216.1 - 2e-36 125.6 0.0 4.4e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 KND93216.1 - 7.6e-31 106.4 0.0 2.2e-30 104.9 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KND93216.1 - 2e-12 46.8 0.3 4.6e-12 45.6 0.3 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KND93216.1 - 9.8e-11 41.6 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KND93216.1 - 1.1e-09 38.0 0.0 0.00014 21.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 KND93216.1 - 0.00039 20.0 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain NUDIX_5 PF16705.5 KND93216.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Fungal_trans PF04082.18 KND93217.1 - 9.9e-16 57.6 0.0 1.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93217.1 - 4.8e-05 23.4 6.2 9.1e-05 22.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_trans_3N PF02885.17 KND93217.1 - 0.046 13.6 0.8 0.092 12.6 0.8 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Peptidase_M3 PF01432.20 KND93220.1 - 1.2e-85 288.5 0.0 2e-85 287.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 KND93220.1 - 0.007 15.1 0.2 0.023 13.3 0.1 1.8 2 0 0 2 2 2 1 Angiotensin-converting enzyme Peptidase_S48 PF03574.15 KND93220.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase family S48 HydF_dimer PF18128.1 KND93220.1 - 0.043 13.9 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain Pkinase_C PF00433.24 KND93221.1 - 0.00012 22.7 0.1 0.00032 21.3 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Melibiase_2 PF16499.5 KND93222.1 - 1.4e-09 37.6 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Alpha galactosidase A CAP59_mtransfer PF11735.8 KND93223.1 - 9.8e-71 238.2 0.0 1.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.22 KND93225.1 - 2.2e-49 168.4 0.0 4.1e-49 167.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Amidase PF01425.21 KND93226.1 - 6.5e-65 219.9 0.0 1.3e-64 218.9 0.0 1.5 1 1 0 1 1 1 1 Amidase 2OG-FeII_Oxy_3 PF13640.6 KND93228.1 - 4.8e-09 37.0 0.0 7.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1235 PF06822.12 KND93228.1 - 0.017 14.4 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) Ion_trans PF00520.31 KND93229.1 - 5.5e-07 29.1 25.5 5.7e-06 25.7 25.5 2.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 KND93229.1 - 0.00035 19.4 12.7 0.013 14.2 2.8 2.2 1 1 1 2 2 2 2 Polycystin cation channel SlyX PF04102.12 KND93229.1 - 0.013 16.0 0.4 0.032 14.9 0.4 1.6 1 0 0 1 1 1 0 SlyX PNTB_4TM PF12769.7 KND93229.1 - 0.023 15.2 0.4 0.023 15.2 0.4 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch p450 PF00067.22 KND93231.1 - 7.3e-33 114.0 0.0 1.2e-28 100.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF3494 PF11999.8 KND93232.1 - 5.6e-42 143.7 20.7 7.5e-42 143.3 20.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Dicer_N PF17895.1 KND93232.1 - 0.015 15.1 1.4 0.12 12.2 0.1 2.2 1 1 1 2 2 2 0 Giardia Dicer N-terminal domain APH PF01636.23 KND93233.1 - 1.4e-09 38.3 0.1 7.2e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND93233.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase ACBP PF00887.19 KND93234.1 - 2.4e-19 69.3 0.7 2.9e-19 69.0 0.7 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein SOG2 PF10428.9 KND93235.1 - 8.8 5.4 19.4 12 5.0 19.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Bromodomain PF00439.25 KND93236.1 - 7.6e-17 61.2 0.1 3.2e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Bromodomain BTB PF00651.31 KND93236.1 - 0.001 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GvpO PF05800.11 KND93237.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Ribosomal_L11 PF00298.19 KND93238.1 - 1.4e-28 99.1 0.5 4.3e-28 97.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KND93238.1 - 4e-25 87.4 0.2 6.4e-25 86.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain PLDc_2 PF13091.6 KND93239.1 - 1.1e-15 57.6 0.0 1.3e-06 28.3 0.0 3.4 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 KND93239.1 - 3e-14 52.5 1.2 1e-06 28.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.20 KND93240.1 - 5.1e-45 151.7 3.5 1.9e-25 88.8 0.1 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KND93240.1 - 6e-10 39.3 0.0 0.00032 20.7 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KND93240.1 - 8.4e-09 35.7 2.0 0.0021 18.4 0.0 4.9 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KND93240.1 - 1.9e-07 31.5 3.0 0.019 15.4 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KND93240.1 - 5e-06 26.6 0.8 0.089 13.0 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 KND93240.1 - 0.00055 19.8 0.4 0.041 13.7 0.0 2.9 3 0 0 3 3 3 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KND93240.1 - 0.00063 19.2 0.3 0.92 8.8 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KND93240.1 - 0.0068 16.3 1.8 0.06 13.3 0.0 2.9 3 0 0 3 3 3 1 AhpC/TSA family UBN_AB PF14075.6 KND93240.1 - 5.2 6.7 6.7 0.17 11.6 0.3 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Actin PF00022.19 KND93241.1 - 9.9e-15 54.0 0.0 4.6e-13 48.6 0.0 2.3 2 0 0 2 2 2 2 Actin FtsA PF14450.6 KND93241.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA Ysc84 PF04366.12 KND93242.1 - 7.9e-30 103.2 0.0 2e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator Tyr-DNA_phospho PF06087.12 KND93243.1 - 1e-136 456.3 0.0 1.2e-136 456.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase MatE PF01554.18 KND93244.1 - 4.7e-49 166.1 25.5 1.1e-31 109.7 8.4 3.4 3 0 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 KND93244.1 - 0.0015 18.6 15.5 0.0015 18.6 15.5 3.5 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain NOG1_N PF17835.1 KND93245.1 - 2.7e-48 164.0 0.0 2.7e-48 164.0 0.0 2.0 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KND93245.1 - 1e-28 99.0 2.4 2.7e-28 97.7 2.4 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KND93245.1 - 1.1e-25 89.1 0.3 2.7e-25 87.9 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KND93245.1 - 2.8e-16 59.6 0.0 7.1e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND93245.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KND93245.1 - 0.008 16.6 0.0 0.26 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KND93245.1 - 0.012 15.5 2.9 0.92 9.4 0.1 3.3 4 1 0 4 4 4 0 RsgA GTPase AAA_23 PF13476.6 KND93245.1 - 0.017 15.7 0.8 5.5 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KND93245.1 - 0.022 14.8 1.2 9 6.3 0.0 3.0 2 1 1 3 3 3 0 Dynamin family NTP_transf_6 PF06042.11 KND93245.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase Roc PF08477.13 KND93245.1 - 0.13 12.5 0.0 0.84 9.9 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pribosyltran PF00156.27 KND93246.1 - 0.025 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Fungal_trans PF04082.18 KND93247.1 - 1.7e-18 66.6 0.1 3e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KND93247.1 - 1.7e-06 28.2 7.3 1.8e-05 24.9 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-Di19 PF05605.12 KND93247.1 - 0.00061 20.0 4.4 0.0016 18.7 4.4 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KND93247.1 - 0.0012 19.4 15.1 0.063 14.1 5.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND93247.1 - 0.17 12.2 3.1 8.8 6.8 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KND93247.1 - 0.35 11.4 14.6 0.37 11.3 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type GDI PF00996.18 KND93248.1 - 1.9e-185 616.5 0.0 8.1e-115 383.8 0.0 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KND93248.1 - 0.037 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 KND93249.1 - 3.4e-10 39.9 4.2 1e-09 38.4 4.2 1.8 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Myb_DNA-binding PF00249.31 KND93251.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF3435 PF11917.8 KND93252.1 - 2.1e-57 194.9 0.0 2.7e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) NACHT PF05729.12 KND93256.1 - 1.8e-06 28.0 4.1 8.3e-05 22.6 0.1 3.2 4 0 0 4 4 4 2 NACHT domain AAA_22 PF13401.6 KND93256.1 - 3e-05 24.3 0.2 0.0094 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND93256.1 - 0.0082 16.5 2.8 0.096 13.1 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KND93256.1 - 0.023 14.0 0.3 0.13 11.5 0.0 2.2 3 0 0 3 3 3 0 KAP family P-loop domain DNA_ligase_ZBD PF03119.16 KND93258.1 - 0.0015 18.5 2.2 0.0025 17.8 2.2 1.3 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain Nudix_N_2 PF14803.6 KND93258.1 - 0.33 10.9 2.7 0.58 10.1 2.7 1.3 1 0 0 1 1 1 0 Nudix N-terminal ECM11 PF15463.6 KND93259.1 - 7.1e-42 143.1 3.8 1.9e-41 141.8 3.8 1.8 1 0 0 1 1 1 1 Extracellular mutant protein 11 Acyl-CoA_dh_1 PF00441.24 KND93261.1 - 4.4e-25 88.6 0.3 8.3e-25 87.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KND93261.1 - 1.2e-23 83.9 0.1 2.9e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KND93261.1 - 3.8e-15 55.8 0.0 7.2e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND93261.1 - 6.6e-07 29.7 0.1 1.2e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 KND93261.1 - 0.14 12.7 0.0 0.39 11.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal RRM_1 PF00076.22 KND93262.1 - 2.5e-09 36.8 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND93262.1 - 0.00026 20.6 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dabb PF07876.12 KND93264.1 - 1.5e-19 70.4 0.0 3.2e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain MFS_1 PF07690.16 KND93266.1 - 2.6e-30 105.6 27.6 2.6e-30 105.6 27.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PCMT PF01135.19 KND93268.1 - 0.083 12.6 1.3 7.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_6 PF08030.12 KND93269.1 - 3.9e-33 114.8 0.0 6.7e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KND93269.1 - 6.7e-19 68.0 0.2 2.5e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 KND93269.1 - 9.6e-18 64.5 11.1 9.6e-18 64.5 11.1 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KND93269.1 - 0.13 12.9 0.0 0.51 11.0 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain UQ_con PF00179.26 KND93271.1 - 4.2e-52 175.5 0.0 4.8e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND93271.1 - 0.0042 16.8 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KND93271.1 - 0.039 14.2 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 KND93271.1 - 0.044 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain SGL PF08450.12 KND93275.1 - 0.0012 18.5 1.4 0.12 12.0 0.0 3.2 2 1 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region RCC1_2 PF13540.6 KND93275.1 - 0.023 14.5 1.7 4.5 7.2 0.3 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat PD40 PF07676.12 KND93275.1 - 0.053 13.5 2.8 0.91 9.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.21 KND93275.1 - 0.086 12.9 0.3 5.2 7.3 0.0 3.6 4 0 0 4 4 4 0 NHL repeat GSDH PF07995.11 KND93275.1 - 0.42 9.9 2.8 0.97 8.7 1.7 2.2 1 1 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Fungal_trans PF04082.18 KND93276.1 - 9.4e-21 74.0 0.0 3.4e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93276.1 - 6.5e-09 35.8 9.8 1e-08 35.1 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KND93277.1 - 1e-38 133.2 10.3 1e-38 133.2 10.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93277.1 - 2e-09 36.9 1.4 2e-09 36.9 1.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KND93277.1 - 0.0019 17.1 2.9 0.0019 17.1 2.9 2.7 2 1 0 2 2 2 2 MFS_1 like family DUF2415 PF10313.9 KND93279.1 - 2.5e-10 40.1 0.0 5.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) DAO PF01266.24 KND93280.1 - 7e-59 200.2 6.9 7.9e-59 200.0 6.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND93280.1 - 0.0011 19.1 0.3 0.0029 17.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND93280.1 - 0.0071 15.6 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 KND93280.1 - 0.02 13.5 0.0 0.63 8.5 0.0 2.5 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 KND93280.1 - 0.071 12.5 0.8 0.33 10.2 0.8 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND93280.1 - 0.085 12.1 0.1 0.33 10.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Avl9 PF09794.9 KND93281.1 - 4.1e-144 479.9 0.0 5.1e-144 479.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KND93281.1 - 8.8e-07 28.8 0.1 9.4e-05 22.1 0.1 2.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KND93281.1 - 2.5e-05 24.2 0.1 0.002 18.1 0.0 2.4 1 1 0 2 2 2 1 Stabilization of polarity axis Pyr_redox_2 PF07992.14 KND93282.1 - 5.3e-35 121.1 0.0 8e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND93282.1 - 6.7e-09 36.2 1.2 3e-08 34.1 0.9 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND93282.1 - 0.00012 21.4 0.4 0.00032 19.9 0.1 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KND93282.1 - 0.00017 20.6 0.5 0.11 11.3 0.1 2.5 2 1 1 3 3 3 2 Tryptophan halogenase DAO PF01266.24 KND93282.1 - 0.00062 19.5 2.9 0.1 12.2 0.0 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND93282.1 - 0.0026 17.1 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND93282.1 - 0.018 14.1 0.5 1.2 8.1 0.1 3.3 5 0 0 5 5 5 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KND93282.1 - 0.068 12.2 2.1 1.5 7.8 2.6 2.3 2 1 0 2 2 2 0 FAD binding domain TPP_enzyme_M PF00205.22 KND93282.1 - 0.084 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain TrkA_N PF02254.18 KND93282.1 - 0.089 13.1 0.0 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 KND93282.1 - 0.11 11.8 2.8 0.1 11.9 1.3 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CoA_binding_2 PF13380.6 KND93282.1 - 0.13 12.8 0.3 10 6.6 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain DUF1067 PF06362.11 KND93282.1 - 0.16 12.8 0.1 0.34 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1067) HI0933_like PF03486.14 KND93282.1 - 1.5 7.5 3.7 2.8 6.6 1.6 2.3 2 1 1 3 3 3 0 HI0933-like protein GIDA PF01134.22 KND93282.1 - 2.4 7.2 5.4 2.2 7.3 3.3 2.0 2 1 1 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 KND93284.1 - 5.9e-30 105.0 0.3 7.6e-30 104.7 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND93284.1 - 0.024 14.9 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AA_permease_2 PF13520.6 KND93285.1 - 1.3e-45 156.1 45.8 1.6e-45 155.8 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND93285.1 - 1.3e-23 83.4 36.4 1.9e-23 82.9 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KND93286.1 - 4.3e-36 124.6 0.0 6.4e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93286.1 - 3.3e-18 65.9 0.0 4.9e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND93286.1 - 0.016 15.2 0.0 0.31 10.9 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KND93286.1 - 0.055 12.8 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Aconitase PF00330.20 KND93287.1 - 1.8e-106 356.9 0.0 1.6e-105 353.8 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KND93287.1 - 2.5e-22 79.6 0.0 1.1e-21 77.5 0.0 2.0 2 0 0 2 2 2 1 Aconitase C-terminal domain Fungal_trans PF04082.18 KND93288.1 - 6.8e-20 71.2 1.4 1.1e-19 70.6 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_MalT PF17874.1 KND93288.1 - 0.058 12.8 0.3 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 MalT-like TPR region DUF2464 PF10240.9 KND93288.1 - 0.2 11.2 1.0 0.53 9.8 0.7 1.8 2 0 0 2 2 2 0 Multivesicular body subunit 12 FAA_hydrolase PF01557.18 KND93289.1 - 2.7e-59 200.5 0.0 3.6e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PNP_phzG_C PF10590.9 KND93290.1 - 1.3e-21 76.4 3.4 9.5e-21 73.6 3.8 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 KND93290.1 - 9.6e-18 64.2 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 KND93290.1 - 0.078 13.6 0.0 0.15 12.7 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cyclin_N PF00134.23 KND93291.1 - 4.1e-06 26.6 0.1 3.8e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain 2-oxoacid_dh PF00198.23 KND93292.1 - 2.4e-77 259.5 0.0 3.5e-77 259.0 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KND93292.1 - 1.1e-15 57.2 3.0 2.2e-15 56.2 3.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 KND93292.1 - 0.031 15.0 0.2 1.4 9.6 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 KND93292.1 - 0.046 13.5 0.1 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like DUF4834 PF16118.5 KND93292.1 - 0.064 14.2 0.9 14 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3614 PF12267.8 KND93292.1 - 0.22 12.0 0.0 0.22 12.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Presenilin PF01080.17 KND93292.1 - 1.1 7.9 7.4 1.6 7.4 7.4 1.1 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 KND93292.1 - 1.4 8.2 8.0 31 3.8 0.0 2.1 2 0 0 2 2 2 0 FAM76 protein Coilin_N PF15862.5 KND93292.1 - 1.9 8.3 5.1 3.4 7.5 5.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 KND93292.1 - 9.4 6.0 10.6 14 5.4 10.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Complex1_LYR PF05347.15 KND93293.1 - 1.3e-07 31.5 0.9 2.4e-07 30.7 0.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cys_Met_Meta_PP PF01053.20 KND93294.1 - 3e-35 121.5 0.0 4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KND93294.1 - 0.0045 16.2 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DnaJ PF00226.31 KND93296.1 - 2.8e-24 85.0 1.1 9.4e-24 83.3 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_2 PF12756.7 KND93296.1 - 7.9e-10 39.0 2.5 6.8e-05 23.1 0.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KND93296.1 - 1.6e-09 37.8 1.4 1.6e-09 37.8 1.4 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND93296.1 - 6e-09 36.0 5.4 3.6e-08 33.5 1.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KND93296.1 - 1.3e-07 31.8 3.8 0.014 16.2 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KND93296.1 - 1.5e-07 31.5 6.1 0.004 17.5 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KND93296.1 - 0.00023 21.1 5.1 0.013 15.5 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2256 PF10013.9 KND93296.1 - 0.013 15.6 1.7 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 KND93296.1 - 0.05 14.3 0.1 3 8.5 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HE PF16278.5 KND93296.1 - 0.097 13.1 0.2 7 7.2 0.0 2.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 KND93296.1 - 0.27 11.7 1.7 3.6 8.2 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-met2 PF12907.7 KND93296.1 - 5 7.3 6.4 19 5.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding SPX PF03105.19 KND93297.1 - 5.1e-55 188.0 0.0 1.5e-53 183.1 0.0 2.4 2 1 0 2 2 2 1 SPX domain zf-C3HC4 PF00097.25 KND93297.1 - 4.2e-08 32.9 9.7 4.2e-08 32.9 9.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND93297.1 - 7.9e-08 32.0 9.4 7.9e-08 32.0 9.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND93297.1 - 2.4e-07 30.5 10.1 8.9e-07 28.7 10.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND93297.1 - 1.7e-06 28.0 11.4 2.1e-06 27.8 9.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KND93297.1 - 1.2e-05 25.5 11.6 1.2e-05 25.5 11.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KND93297.1 - 3.1e-05 23.9 8.1 0.00011 22.2 8.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND93297.1 - 0.00024 21.0 9.6 0.00024 21.0 9.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KND93297.1 - 0.0028 17.5 8.3 0.0089 15.9 8.3 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KND93297.1 - 0.0041 17.4 4.5 0.016 15.5 4.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KND93297.1 - 0.015 15.1 4.8 0.015 15.1 4.8 2.6 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain HTH_Tnp_1 PF01527.20 KND93297.1 - 0.052 13.9 0.3 0.18 12.1 0.3 2.0 1 0 0 1 1 1 0 Transposase zf-RING_10 PF16685.5 KND93297.1 - 0.67 10.1 7.6 1.8 8.8 7.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 KND93297.1 - 6.9 6.8 12.2 1.3 9.1 7.8 2.3 2 1 0 2 2 2 0 Double zinc ribbon R3H PF01424.22 KND93298.1 - 1.5e-12 47.3 0.0 3.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KND93298.1 - 1.2e-09 37.8 0.5 3.2e-09 36.5 0.5 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KND93298.1 - 0.012 15.7 0.6 0.047 13.8 0.6 2.1 1 0 0 1 1 1 0 G-patch domain Peptidase_C54 PF03416.19 KND93299.1 - 1e-91 307.2 0.0 1.5e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Histone_H2A_C PF16211.5 KND93300.1 - 1.5e-21 75.9 2.9 2.6e-21 75.1 2.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KND93300.1 - 6.9e-17 62.0 0.0 9.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KND93300.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 KND93300.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 KND93301.1 - 4.6e-22 78.8 1.9 5.8e-22 78.5 1.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KND93301.1 - 4.7e-05 23.6 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KND93301.1 - 0.00026 21.4 0.0 0.00044 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KND93301.1 - 0.044 13.4 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain TP_methylase PF00590.20 KND93302.1 - 1.7e-23 83.7 0.0 2.9e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 KND93303.1 - 4.3e-07 30.0 0.2 7.3e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND93303.1 - 5e-05 23.5 0.3 9.5e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KND93303.1 - 0.00048 20.1 1.1 0.0012 18.9 1.1 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KND93303.1 - 0.0082 16.2 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 DBF zinc finger pPIWI_RE_X PF13111.6 KND93303.1 - 0.073 12.3 2.5 0.11 11.7 2.5 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain zf-C2H2 PF00096.26 KND93303.1 - 0.087 13.3 0.4 0.16 12.5 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-U1 PF06220.12 KND93303.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger TERB2 PF15101.6 KND93303.1 - 0.3 11.1 4.0 0.51 10.4 4.0 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDHD PF02862.17 KND93303.1 - 9 6.4 6.1 2.3 8.4 3.3 1.4 2 0 0 2 2 2 0 DDHD domain UQ_con PF00179.26 KND93304.1 - 1.2e-34 119.0 0.0 1.3e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_trans_1_4 PF13692.6 KND93305.1 - 2.8e-07 31.0 0.0 1.3e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KND93305.1 - 0.00099 19.5 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KND93305.1 - 0.0021 17.6 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-TFIIIC PF12660.7 KND93306.1 - 4.8e-12 45.7 1.1 3.3e-11 43.0 1.4 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex zf-TFIIIC PF12660.7 KND93307.1 - 0.00059 19.7 0.9 0.006 16.5 1.1 2.5 2 1 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex Peptidase_C13 PF01650.18 KND93308.1 - 3.7e-40 138.0 0.3 4.8e-40 137.7 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Pyrid_ox_like PF16242.5 KND93310.1 - 1.8e-25 89.3 0.0 2.7e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KND93310.1 - 6.3e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 KND93310.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain Cation_efflux PF01545.21 KND93311.1 - 7.3e-47 159.7 2.3 9.8e-47 159.3 2.3 1.2 1 0 0 1 1 1 1 Cation efflux family Mito_carr PF00153.27 KND93312.1 - 1.3e-56 188.5 3.9 3.3e-18 65.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.6 KND93313.1 - 1.8e-07 31.8 0.2 6.3e-07 30.0 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND93313.1 - 7.5e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF167 PF02594.16 KND93314.1 - 2e-19 69.4 0.1 2.7e-19 69.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 HAD_SAK_1 PF10307.9 KND93316.1 - 1.9e-76 256.4 0.0 2.4e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins GRP PF07172.11 KND93316.1 - 3.8 8.3 33.4 0.094 13.4 23.6 2.3 2 0 0 2 2 2 0 Glycine rich protein family Pkinase PF00069.25 KND93317.1 - 8.4e-25 87.6 0.0 4.8e-24 85.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93317.1 - 2.3e-06 27.1 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase tRNA_m1G_MT PF01746.21 KND93318.1 - 1.5e-24 86.8 0.0 2e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DNA_primase_S PF01896.19 KND93319.1 - 2.4e-66 223.1 0.1 3.5e-66 222.6 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit COQ9 PF08511.11 KND93322.1 - 5.6e-31 106.1 0.0 8.2e-31 105.6 0.0 1.3 1 0 0 1 1 1 1 COQ9 SMC_N PF02463.19 KND93324.1 - 9e-23 80.9 0.4 5.1e-22 78.4 0.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KND93324.1 - 3.7e-18 66.7 7.8 3.7e-18 66.7 7.8 4.5 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KND93324.1 - 2.3e-11 44.0 8.6 2.3e-11 44.0 8.6 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KND93324.1 - 0.0011 18.9 7.5 0.0026 17.6 0.1 3.5 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 KND93324.1 - 0.0016 17.4 10.1 0.0016 17.4 10.1 5.4 3 2 2 5 5 5 2 Spc7 kinetochore protein AAA_29 PF13555.6 KND93324.1 - 0.0072 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1664 PF07889.12 KND93324.1 - 0.0074 16.3 30.6 0.37 10.8 0.5 6.3 4 2 1 6 6 6 4 Protein of unknown function (DUF1664) SMC_hinge PF06470.13 KND93324.1 - 0.015 15.6 0.1 0.09 13.1 0.0 2.4 3 0 0 3 3 3 0 SMC proteins Flexible Hinge Domain ABC_tran PF00005.27 KND93324.1 - 0.61 10.6 24.4 0.3 11.6 1.7 5.2 4 2 0 4 4 4 0 ABC transporter Sec34 PF04136.15 KND93324.1 - 3.1 7.7 21.2 1.9 8.3 0.1 5.0 4 1 0 5 5 5 0 Sec34-like family MIF4G PF02854.19 KND93326.1 - 2e-20 73.4 0.1 2.6e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 MIF4G domain COPI_C PF06957.11 KND93326.1 - 0.39 9.4 5.4 0.69 8.6 5.4 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Cwf_Cwc_15 PF04889.12 KND93326.1 - 5.8 6.6 23.5 6.3 6.5 2.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SRP14 PF02290.15 KND93327.1 - 3.7e-28 97.7 0.0 5.2e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein SF3a60_bindingd PF12108.8 KND93327.1 - 0.072 13.0 0.0 6.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain RRM_1 PF00076.22 KND93329.1 - 3.3e-45 151.8 0.0 1.3e-17 63.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KND93329.1 - 8e-05 22.6 0.3 5.2 7.2 0.0 4.2 3 2 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.10 KND93329.1 - 0.0011 18.6 0.0 0.064 12.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RRM_3 PF08777.11 KND93329.1 - 0.0026 17.8 0.0 3.7 7.6 0.0 3.9 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 KND93329.1 - 0.031 14.1 0.0 8.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KND93329.1 - 0.11 12.3 0.0 23 4.8 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PknH_C PF14032.6 KND93329.1 - 0.19 11.6 0.3 39 4.0 0.0 3.0 3 0 0 3 3 3 0 PknH-like extracellular domain Pyr_redox_2 PF07992.14 KND93330.1 - 3.7e-66 223.3 5.3 5e-66 222.9 5.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KND93330.1 - 2.8e-39 133.8 1.7 8.7e-39 132.2 0.0 2.7 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KND93330.1 - 5.4e-25 87.8 10.4 2.1e-21 76.3 1.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND93330.1 - 2e-11 43.9 1.9 1.5e-06 28.3 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND93330.1 - 5.7e-10 38.8 9.6 4.8e-08 32.5 3.9 2.4 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 KND93330.1 - 1e-09 38.3 9.4 4.1e-09 36.3 0.3 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND93330.1 - 2.6e-08 33.4 7.2 1.1e-06 28.0 2.3 2.8 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 KND93330.1 - 8e-08 31.8 2.9 0.0065 15.8 0.0 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KND93330.1 - 9e-08 32.1 13.6 0.0018 17.9 0.5 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 KND93330.1 - 4.6e-07 28.9 13.1 0.00012 21.0 2.0 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 KND93330.1 - 4.4e-06 26.1 3.2 0.0003 20.1 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 KND93330.1 - 3.6e-05 23.2 6.3 0.0046 16.2 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND93330.1 - 0.0001 21.5 3.6 0.0072 15.4 0.2 2.6 2 1 0 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 KND93330.1 - 0.00011 21.6 9.1 0.05 12.8 1.4 2.8 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 KND93330.1 - 0.00036 19.8 0.8 0.4 9.8 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) RuBisCO_large PF00016.20 KND93330.1 - 0.025 13.8 1.0 2.1 7.5 0.0 3.0 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain NAD_binding_7 PF13241.6 KND93330.1 - 0.062 13.8 6.5 1.5 9.3 0.6 3.2 2 2 1 3 3 3 0 Putative NAD(P)-binding XdhC_C PF13478.6 KND93330.1 - 0.13 12.8 0.1 5 7.6 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain Trp_halogenase PF04820.14 KND93330.1 - 0.15 10.9 7.2 0.059 12.2 0.7 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 KND93330.1 - 0.16 11.4 2.6 3.2 7.1 0.7 2.5 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KND93330.1 - 0.23 11.3 7.3 0.083 12.8 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KND93330.1 - 1.6 8.3 5.9 3.4 7.2 0.4 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MA3 PF02847.17 KND93331.1 - 5.8e-11 42.4 0.0 2.2e-10 40.5 0.0 1.9 1 1 0 1 1 1 1 MA3 domain MFS_1 PF07690.16 KND93333.1 - 2.5e-33 115.5 25.0 8e-27 94.1 5.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93333.1 - 6.2e-10 38.5 5.0 6.2e-10 38.5 5.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KND93333.1 - 1.4 7.7 21.5 0.23 10.3 4.4 3.8 2 2 1 3 3 3 0 MFS_1 like family LCAT PF02450.15 KND93334.1 - 5.4e-107 358.3 0.0 7.2e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2013 PF09431.10 KND93334.1 - 1.1e-49 168.2 3.1 2.3e-49 167.1 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF1749 PF08538.10 KND93334.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF1917 PF08939.10 KND93336.1 - 1.5e-79 267.6 0.0 1.9e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TIR_2 PF13676.6 KND93336.1 - 0.017 15.8 0.3 0.061 13.9 0.3 1.7 1 1 1 2 2 2 0 TIR domain Acetyltransf_1 PF00583.25 KND93337.1 - 6.2e-18 65.1 0.0 8e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KND93337.1 - 5.7e-10 39.0 0.0 9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KND93337.1 - 4.9e-09 36.2 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND93337.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KND93337.1 - 1.2e-05 25.1 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KND93337.1 - 1.9e-05 25.4 0.0 2.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KND93337.1 - 0.0003 20.9 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KND93337.1 - 0.045 13.9 0.1 0.088 13.0 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallopep PF12044.8 KND93338.1 - 5.6e-157 522.7 0.0 1.1e-156 521.8 0.0 1.4 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 KND93338.1 - 0.00076 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 KND93338.1 - 0.07 13.3 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Whi5 PF08528.11 KND93339.1 - 2.2e-10 39.9 0.2 4e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Whi5 like PH PF00169.29 KND93340.1 - 5.7e-05 23.6 0.2 0.00018 22.0 0.1 2.0 2 0 0 2 2 2 1 PH domain WEMBL PF05701.11 KND93340.1 - 0.038 12.7 2.3 0.075 11.7 2.3 1.4 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Prominin PF05478.11 KND93340.1 - 0.15 10.0 0.4 0.22 9.5 0.4 1.1 1 0 0 1 1 1 0 Prominin CDP-OH_P_transf PF01066.21 KND93341.1 - 4.1e-14 53.1 0.3 9.2e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Transp_cyt_pur PF02133.15 KND93342.1 - 3.7e-94 316.0 33.5 4.2e-94 315.8 33.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin IBN_N PF03810.19 KND93343.1 - 3.1e-07 30.2 0.1 1.4e-06 28.2 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KND93343.1 - 1.5e-06 28.3 0.7 4.1e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IFRD PF05004.13 KND93343.1 - 0.0041 16.3 0.0 0.0088 15.2 0.0 1.5 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) MOR2-PAG1_N PF14222.6 KND93343.1 - 0.11 11.4 0.1 0.31 9.9 0.0 1.7 2 0 0 2 2 2 0 Cell morphogenesis N-terminal IPPT PF01715.17 KND93343.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 IPP transferase DASH_Ask1 PF08655.10 KND93344.1 - 2.1e-30 104.4 0.1 3.7e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 GCP_C_terminal PF04130.13 KND93345.1 - 7.6e-77 258.8 0.0 1.6e-76 257.7 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KND93345.1 - 2.7e-19 69.9 0.0 4.9e-09 36.3 0.0 2.4 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal CHD5 PF04420.14 KND93345.1 - 0.055 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF3782 PF12644.7 KND93345.1 - 0.13 12.4 0.4 0.43 10.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Eaf7 PF07904.13 KND93346.1 - 5.3e-27 94.3 0.1 5.3e-27 94.3 0.1 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 PPP4R2 PF09184.11 KND93346.1 - 0.034 13.7 7.8 0.056 13.0 7.8 1.3 1 0 0 1 1 1 0 PPP4R2 Sin_N PF04801.13 KND93346.1 - 0.52 9.5 4.7 1 8.5 4.7 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Pol_alpha_B_N PF08418.10 KND93346.1 - 3.3 7.6 15.2 1.7 8.5 7.1 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.12 KND93346.1 - 4.6 7.0 8.2 8.6 6.1 8.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ResIII PF04851.15 KND93347.1 - 4.9e-26 91.7 0.0 9.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND93347.1 - 2.6e-15 56.7 0.0 1.6e-13 51.0 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND93347.1 - 7.4e-14 51.9 0.1 1.6e-13 50.8 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KND93347.1 - 1.4e-06 28.1 0.1 2.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KND93347.1 - 0.003 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 KND93347.1 - 0.008 15.1 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ERCC3_RAD25_C PF16203.5 KND93347.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase KH_1 PF00013.29 KND93348.1 - 1.3e-30 105.0 0.6 7.5e-07 28.9 0.0 7.4 8 0 0 8 8 8 5 KH domain PRRSV_Env PF02340.15 KND93348.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 PRRSV putative envelope protein HAD_2 PF13419.6 KND93351.1 - 3.3e-11 43.6 0.0 4.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND93351.1 - 2.1e-09 38.0 0.0 9.9e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND93351.1 - 0.052 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Med21 PF11221.8 KND93352.1 - 7.9e-48 162.4 6.9 8.8e-48 162.2 6.9 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 KND93352.1 - 0.0039 16.6 7.4 0.29 10.5 0.6 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CtIP_N PF10482.9 KND93352.1 - 0.0058 16.7 2.8 0.0078 16.3 1.4 1.8 1 1 1 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain Med9 PF07544.13 KND93352.1 - 0.016 15.3 3.5 0.016 15.3 3.5 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Med26_C PF15693.5 KND93352.1 - 0.034 14.3 0.4 0.038 14.1 0.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Phi-29_GP16_7 PF06720.11 KND93352.1 - 0.039 13.8 1.5 0.072 12.9 0.8 1.8 1 1 1 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 Fib_alpha PF08702.10 KND93352.1 - 0.084 13.1 2.0 0.23 11.7 2.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 KND93352.1 - 0.086 11.3 0.4 0.086 11.3 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spore_III_AB PF09548.10 KND93352.1 - 0.13 12.3 2.5 0.18 11.9 2.5 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TMPIT PF07851.13 KND93352.1 - 0.14 11.3 0.4 0.22 10.7 0.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4455 PF14643.6 KND93352.1 - 0.32 9.6 6.0 0.14 10.8 3.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) Tropomyosin_1 PF12718.7 KND93352.1 - 0.42 10.8 8.8 0.86 9.8 7.6 1.9 1 1 1 2 2 2 0 Tropomyosin like OmpH PF03938.14 KND93352.1 - 1 9.7 9.6 2.4 8.5 9.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) BST2 PF16716.5 KND93352.1 - 1.6 9.4 8.9 14 6.4 0.7 2.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 APG6_N PF17675.1 KND93352.1 - 1.7 9.2 11.9 5.5 7.5 11.9 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region PP28 PF10252.9 KND93353.1 - 1.3e-27 96.0 14.4 1.3e-27 96.0 14.4 3.2 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 PACT_coil_coil PF10495.9 KND93353.1 - 0.8 10.3 10.5 1.5 9.4 7.8 2.4 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein SURF6 PF04935.12 KND93354.1 - 1.4e-48 165.4 37.9 1.4e-48 165.4 37.9 3.5 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 KND93354.1 - 1.8e-15 57.3 0.3 1.8e-15 57.3 0.3 7.5 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.11 KND93355.1 - 2.3e-67 227.0 0.2 3e-67 226.6 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) GTP_EFTU PF00009.27 KND93358.1 - 7.5e-34 117.0 4.7 2.2e-32 112.2 4.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KND93358.1 - 3.5e-27 94.6 0.3 9.2e-27 93.2 0.3 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KND93358.1 - 1.9e-09 37.6 0.4 5.8e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND93358.1 - 1.2e-05 25.3 1.3 0.0003 20.7 0.2 2.4 1 1 1 2 2 2 1 RsgA GTPase IF2_N PF04760.15 KND93358.1 - 7.3e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 KND93358.1 - 0.00021 20.8 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KND93358.1 - 0.00068 19.1 0.1 0.0018 17.8 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KND93358.1 - 0.0011 18.7 0.2 0.0027 17.4 0.2 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 KND93358.1 - 0.0019 17.8 0.2 0.004 16.7 0.2 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 KND93358.1 - 0.0053 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 KND93358.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ras PF00071.22 KND93358.1 - 0.02 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Ras family GTP_EFTU_D2 PF03144.25 KND93358.1 - 0.054 13.9 0.1 23 5.5 0.0 3.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Ribo_biogen_C PF04034.13 KND93359.1 - 1.1e-48 164.1 0.1 1.5e-48 163.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KND93359.1 - 4.6e-12 45.5 0.7 9.8e-12 44.5 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI HUN PF08729.10 KND93360.1 - 1.2e-07 31.6 0.2 2.5e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF2457 PF10446.9 KND93362.1 - 0.49 9.5 4.7 0.58 9.2 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) VHS PF00790.19 KND93363.1 - 5.2e-45 152.8 0.0 1.7e-44 151.1 0.0 1.9 3 0 0 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 KND93363.1 - 2.9e-19 69.4 0.1 6.2e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 KND93363.1 - 8.6e-19 67.6 0.6 2.2e-18 66.3 0.1 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KND93363.1 - 2e-07 30.5 0.1 6.2e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain Pro-kuma_activ PF09286.11 KND93365.1 - 4.6e-39 133.9 0.0 9e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KND93365.1 - 0.004 16.5 0.1 0.0062 15.8 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Metallophos PF00149.28 KND93368.1 - 2.6e-14 54.2 0.1 4.7e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_N PF01213.19 KND93368.1 - 0.12 11.9 1.2 0.17 11.3 1.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fungal_trans_2 PF11951.8 KND93369.1 - 9.2e-09 34.6 0.6 1.3e-08 34.0 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93369.1 - 0.00018 21.6 3.9 0.0003 20.8 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Frizzled PF01534.17 KND93369.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DHO_dh PF01180.21 KND93371.1 - 5.8e-65 219.4 0.1 7.7e-54 182.9 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 KND93371.1 - 0.00025 20.6 0.5 0.52 9.7 0.1 2.5 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.18 KND93371.1 - 0.04 12.9 2.6 0.16 10.9 0.9 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase TOM13 PF08219.11 KND93372.1 - 6.2e-38 128.6 0.0 8.2e-38 128.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 KND93373.1 - 1.2e-13 51.3 5.7 1.2e-13 51.3 5.7 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein Cep57_MT_bd PF06657.13 KND93373.1 - 0.033 14.6 4.9 0.57 10.7 1.5 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PEP_mutase PF13714.6 KND93374.1 - 3.1e-58 197.1 0.2 3.5e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF2848 PF11010.8 KND93374.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) tRNA_int_endo PF01974.17 KND93375.1 - 2.3e-18 66.0 0.0 4.5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KND93375.1 - 8.6e-06 25.3 0.0 0.021 14.5 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.6 KND93376.1 - 1e-12 47.9 0.2 2.5e-06 27.1 0.0 3.4 2 1 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KND93376.1 - 5.4e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KND93376.1 - 0.00047 20.0 0.1 0.0032 17.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 SGS PF05002.15 KND93377.1 - 5e-29 100.2 1.2 5e-29 100.2 1.2 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 KND93377.1 - 1.5e-06 29.1 0.0 3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KND93377.1 - 0.0025 17.8 2.3 0.2 11.9 0.2 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND93377.1 - 0.032 14.1 0.2 0.13 12.2 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KND93377.1 - 0.046 14.4 3.6 0.41 11.3 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat OPT PF03169.15 KND93378.1 - 8.1e-139 464.1 46.7 9.4e-139 463.8 46.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 KND93379.1 - 8.2e-32 110.5 30.1 4e-27 95.1 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93379.1 - 3.4e-31 108.6 24.7 2.2e-23 82.9 8.4 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter ABC2_membrane PF01061.24 KND93380.1 - 1.7e-87 292.3 57.1 1.1e-48 165.4 21.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KND93380.1 - 7.6e-38 128.3 11.2 2e-34 117.3 0.1 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 KND93380.1 - 1e-29 103.8 0.0 1e-15 58.5 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 KND93380.1 - 2.8e-18 66.3 0.1 8.8e-18 64.7 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KND93380.1 - 3.4e-06 27.3 0.2 0.037 14.2 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KND93380.1 - 1.4e-05 24.8 0.3 0.00064 19.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KND93380.1 - 2.1e-05 25.0 0.3 0.017 15.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND93380.1 - 3.3e-05 23.9 0.2 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 KND93380.1 - 0.00021 20.5 15.6 0.00021 20.5 15.6 3.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KND93380.1 - 0.00033 20.3 0.6 0.035 13.8 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KND93380.1 - 0.0004 20.3 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KND93380.1 - 0.00077 20.0 0.1 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KND93380.1 - 0.004 16.6 0.0 0.13 11.7 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 KND93380.1 - 0.0071 16.8 0.6 1.3 9.5 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND93380.1 - 0.019 15.2 0.8 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KND93380.1 - 0.021 14.7 0.0 0.88 9.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 KND93380.1 - 0.036 13.8 0.5 2.2 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KND93380.1 - 0.037 13.6 2.0 0.26 10.9 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KND93380.1 - 0.072 13.5 0.2 11 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 KND93380.1 - 0.19 11.7 1.9 4.8 7.1 0.4 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KND93380.1 - 0.23 11.1 0.9 23 4.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KND93380.1 - 0.31 10.8 0.7 11 5.7 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase adh_short PF00106.25 KND93381.1 - 4.1e-05 23.1 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND93381.1 - 0.0019 18.2 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 KND93382.1 - 3.3e-53 181.1 0.0 4.2e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 VCBS PF13517.6 KND93383.1 - 2.3e-32 111.4 39.7 3.4e-09 37.2 5.0 7.4 3 1 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KND93383.1 - 1.7e-26 93.7 0.0 3.9e-16 59.9 0.0 2.7 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND93383.1 - 7.3e-15 55.5 0.0 2e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KND93383.1 - 2.7e-11 43.1 6.7 1.7 8.0 0.0 8.1 6 2 2 8 8 8 4 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KND93383.1 - 7.7e-07 29.1 28.0 2.5 8.3 0.7 7.9 7 0 0 7 7 7 3 FG-GAP repeat Dockerin_1 PF00404.18 KND93383.1 - 2.9e-06 27.4 8.9 6.1 7.1 0.0 7.3 7 0 0 7 7 7 1 Dockerin type I domain PliI PF16743.5 KND93383.1 - 0.0024 17.6 2.0 5.2 6.8 0.0 5.4 7 0 0 7 7 7 1 Periplasmic lysozyme inhibitor of I-type lysozyme Lipase_GDSL_3 PF14606.6 KND93383.1 - 0.2 11.8 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SPC22 PF04573.12 KND93384.1 - 2.4e-38 131.3 0.3 3.1e-37 127.7 0.3 2.0 1 1 0 1 1 1 1 Signal peptidase subunit Peptidase_C48 PF02902.19 KND93385.1 - 1e-33 117.0 0.0 1.8e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 KND93386.1 - 7.5e-23 80.4 4.9 0.0001 23.0 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 KND93386.1 - 0.00092 18.0 0.0 0.12 11.0 0.0 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KND93386.1 - 0.017 15.4 0.0 1.4 9.3 0.0 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND93386.1 - 0.02 14.2 0.0 0.39 10.0 0.0 2.8 4 0 0 4 4 4 0 WD40-like domain Proteasome PF00227.26 KND93387.1 - 2.9e-38 131.3 0.0 4.6e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit zf-RanBP PF00641.18 KND93388.1 - 1.4e-18 65.9 12.5 5.3e-11 41.6 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 KND93388.1 - 2e-08 33.9 0.0 6.4e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 KND93388.1 - 2.3e-06 28.2 0.0 3.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 KND93390.1 - 5.7e-27 93.4 2.7 2.8e-06 28.0 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 KND93390.1 - 5.3e-26 90.7 0.1 5.6e-25 87.4 0.1 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 KND93390.1 - 6.5e-05 23.2 0.8 0.092 13.1 0.2 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain XRN_M PF17846.1 KND93391.1 - 3.8e-99 332.6 2.2 7e-99 331.8 2.2 1.4 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KND93391.1 - 5.6e-80 268.3 0.0 8.7e-80 267.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KND93391.1 - 1.7e-71 240.0 0.0 2.9e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KND93391.1 - 8e-36 122.1 0.1 2.6e-35 120.5 0.1 2.0 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KND93391.1 - 2.8e-18 65.8 0.0 5.7e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KND93391.1 - 7.4e-07 29.2 0.1 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DEAD PF00270.29 KND93392.1 - 2.7e-47 160.8 0.0 1e-46 158.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND93392.1 - 4.8e-32 110.6 0.0 1e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND93392.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 KND93392.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sugar_tr PF00083.24 KND93393.1 - 1.1e-111 373.9 20.7 1.2e-111 373.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND93393.1 - 8.3e-30 103.9 21.2 8.3e-30 103.9 21.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ADH_N PF08240.12 KND93394.1 - 1.3e-07 31.5 0.1 1.7e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KND93394.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CarboxypepD_reg PF13620.6 KND93394.1 - 0.11 12.8 1.4 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain GCD14 PF08704.10 KND93395.1 - 7.3e-64 215.8 0.0 9.2e-47 159.8 0.0 2.6 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit tRNA-synt_1e PF01406.19 KND93396.1 - 1.2e-113 379.5 0.0 2e-113 378.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KND93396.1 - 8.2e-06 24.8 0.2 0.05 12.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 KND93396.1 - 0.072 12.0 0.0 0.072 12.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain UQ_con PF00179.26 KND93397.1 - 1.3e-50 170.7 0.0 1.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND93397.1 - 0.059 13.1 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_hydro_18 PF00704.28 KND93398.1 - 4e-12 46.5 0.0 9e-12 45.3 0.0 1.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 ThrE PF06738.12 KND93399.1 - 1.7e-50 171.6 19.3 8.9e-48 162.8 0.9 2.9 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KND93399.1 - 4e-12 46.4 12.0 4e-12 46.4 12.0 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE LSM PF01423.22 KND93401.1 - 5.5e-17 61.2 0.2 7.9e-17 60.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND93401.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain TPR_2 PF07719.17 KND93402.1 - 6.9e-06 25.8 0.5 2.4 8.5 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KND93402.1 - 1.7e-05 25.0 0.1 0.0027 18.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND93402.1 - 9.2e-05 22.1 0.8 0.82 9.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat UBA PF00627.31 KND93402.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DIOX_N PF14226.6 KND93403.1 - 2e-31 109.2 0.0 3.5e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND93403.1 - 8e-18 64.8 0.1 1.7e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KND93404.1 - 2.4e-09 37.2 4.2 2.4e-09 37.2 4.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KND93405.1 - 4.2e-10 39.4 0.6 3.8e-07 29.7 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND93405.1 - 3.6e-08 33.5 0.4 7.9e-07 29.2 0.4 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND93405.1 - 2.4e-07 30.7 1.4 4.5e-06 26.5 0.9 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND93405.1 - 8.6e-06 25.2 1.2 9.2e-05 21.8 1.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND93405.1 - 2.5e-05 23.6 1.5 4.1e-05 22.8 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KND93405.1 - 0.00038 19.3 0.5 0.00061 18.6 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KND93405.1 - 0.0077 15.6 0.1 0.072 12.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KND93405.1 - 0.011 15.2 1.1 0.016 14.6 1.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KND93405.1 - 0.016 14.3 1.8 0.15 11.1 1.8 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 KND93405.1 - 0.031 13.3 1.1 0.047 12.8 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KND93405.1 - 0.035 13.4 0.4 0.059 12.6 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KND93405.1 - 0.089 11.6 0.9 0.22 10.3 0.2 1.9 1 1 1 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 KND93405.1 - 0.16 11.6 0.2 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 KND93405.1 - 0.16 11.9 1.5 6.4 6.7 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KND93405.1 - 0.18 12.4 1.0 0.45 11.1 1.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KND93405.1 - 0.28 10.4 0.7 0.57 9.4 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 KND93406.1 - 1.2e-20 73.8 39.9 4e-17 62.2 19.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF805 PF05656.14 KND93406.1 - 4.4 7.8 6.7 0.51 10.8 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Nop16 PF09420.10 KND93408.1 - 6e-64 215.9 0.3 6.8e-64 215.7 0.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Rit1_C PF17184.4 KND93409.1 - 1.8e-36 126.0 0.0 2.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain GFO_IDH_MocA PF01408.22 KND93410.1 - 4.3e-10 40.5 0.0 9.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 KND93410.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain LSM PF01423.22 KND93411.1 - 2.3e-23 81.7 0.2 2.5e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND93411.1 - 0.033 14.3 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KND93411.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain DNA_pol_A_exo1 PF01612.20 KND93412.1 - 4.2e-09 36.4 0.0 6.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Peptidase_M41 PF01434.18 KND93413.1 - 7.9e-68 228.1 0.4 2e-67 226.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KND93413.1 - 2.8e-41 141.0 0.0 6e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND93413.1 - 2.8e-13 49.4 0.0 7.5e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KND93413.1 - 1.5e-08 35.0 0.0 3.3e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 KND93413.1 - 0.0028 16.9 0.1 0.0081 15.4 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 KND93413.1 - 0.0034 17.4 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KND93413.1 - 0.0058 17.2 0.2 2.9 8.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KND93413.1 - 0.01 16.0 0.0 0.084 13.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KND93413.1 - 0.016 15.4 0.1 1.5 9.1 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KND93413.1 - 0.017 15.5 0.5 0.59 10.5 0.1 3.0 2 1 0 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 KND93413.1 - 0.033 13.9 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND93413.1 - 0.085 13.0 0.1 0.6 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KND93413.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_L_2 PF13656.6 KND93414.1 - 7.6e-22 76.9 0.1 9.8e-22 76.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KND93414.1 - 0.00018 20.9 0.0 0.0012 18.3 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HCO3_cotransp PF00955.21 KND93415.1 - 2.2e-47 162.0 2.8 1.8e-36 126.1 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family HCO3_cotransp PF00955.21 KND93416.1 - 1.6e-07 30.5 0.1 2.1e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 HCO3- transporter family 3HCDH_N PF02737.18 KND93417.1 - 1e-51 175.4 1.3 1.3e-51 175.1 1.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KND93417.1 - 3.2e-33 114.2 0.0 6.5e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 KND93417.1 - 0.00039 20.7 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 KND93417.1 - 0.0017 18.5 0.3 0.0041 17.3 0.2 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 KND93417.1 - 0.019 14.2 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND93417.1 - 0.04 13.5 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_32 PF13679.6 KND93417.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KND93417.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phasin_2 PF09361.10 KND93417.1 - 0.12 12.7 1.8 18 5.7 0.0 2.5 2 1 0 2 2 2 0 Phasin protein F420_oxidored PF03807.17 KND93417.1 - 0.24 12.0 1.7 1 10.0 1.7 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 KND93417.1 - 0.24 10.4 0.6 0.36 9.8 0.6 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TIMELESS PF04821.14 KND93418.1 - 2e-89 299.5 0.6 6.9e-89 297.8 0.0 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KND93418.1 - 1.2e-29 104.0 3.7 1.2e-29 104.0 3.7 3.9 3 1 1 4 4 4 1 Timeless protein C terminal region MIEAP PF16026.5 KND93418.1 - 0.018 15.3 0.3 0.06 13.6 0.3 1.9 1 0 0 1 1 1 0 Mitochondria-eating protein Hormone_1 PF00103.20 KND93418.1 - 0.33 10.7 2.4 1 9.1 1.3 2.2 2 0 0 2 2 2 0 Somatotropin hormone family Homeodomain PF00046.29 KND93419.1 - 7e-18 64.2 3.0 1.4e-17 63.3 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KND93419.1 - 0.0014 18.5 1.6 0.01 15.7 0.1 2.8 2 0 0 2 2 2 1 Homeobox KN domain TRAPPC9-Trs120 PF08626.11 KND93421.1 - 0 1288.6 0.0 0 1288.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Pneumo_att_G PF05539.11 KND93421.1 - 1.8 8.1 3.3 3.2 7.3 3.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Sugar_tr PF00083.24 KND93422.1 - 7.5e-118 394.2 27.0 8.7e-118 394.0 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND93422.1 - 6.6e-20 71.3 29.7 6.6e-20 71.3 29.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Trehalase PF01204.18 KND93422.1 - 0.18 10.6 0.8 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Trehalase BRCT PF00533.26 KND93423.1 - 8.1e-08 32.5 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND93423.1 - 6.3e-06 26.5 0.0 1.2e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KND93423.1 - 0.00029 20.7 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 KND93423.1 - 0.017 15.2 0.0 7.5 6.7 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain PGA_cap PF09587.10 KND93425.1 - 0.1 12.0 0.4 0.19 11.1 0.4 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Ribosomal_L28e PF01778.17 KND93426.1 - 2e-40 138.1 2.5 2e-40 138.1 2.5 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KND93426.1 - 2e-28 98.9 13.1 2e-28 98.9 13.1 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KND93426.1 - 0.00024 20.6 15.7 0.00033 20.1 15.7 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 KND93426.1 - 0.0092 14.6 22.4 0.013 14.2 22.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 KND93426.1 - 0.026 14.3 2.2 0.051 13.3 1.9 1.7 1 1 0 1 1 1 0 Conserved carboxylase domain Reovirus_cap PF00979.17 KND93426.1 - 0.097 11.8 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 DUF305 PF03713.13 KND93426.1 - 5.7 7.1 8.1 0.46 10.6 2.4 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF305) Nop14 PF04147.12 KND93426.1 - 9.8 4.2 27.5 13 3.8 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.22 KND93427.1 - 7e-45 152.5 0.0 8.8e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND93427.1 - 4.9e-16 59.0 0.0 7.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND93427.1 - 9.3e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KND93427.1 - 1.6e-05 24.5 0.0 6.4e-05 22.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KND93427.1 - 0.00029 20.3 0.0 0.0007 19.1 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KND93427.1 - 0.00032 20.7 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND93427.1 - 0.0027 17.6 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 KND93427.1 - 0.03 14.3 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KND93427.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KND93427.1 - 0.15 11.5 0.0 1.9 8.0 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.25 KND93428.1 - 7.5e-36 123.8 0.0 1.2e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KND93428.1 - 1.2e-18 67.3 7.8 2.5e-18 66.3 7.8 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Peptidase_C54 PF03416.19 KND93428.1 - 0.02 14.3 0.4 0.036 13.5 0.4 1.3 1 0 0 1 1 1 0 Peptidase family C54 TssO PF17561.2 KND93428.1 - 0.049 13.7 4.1 0.092 12.9 4.1 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO NPIP PF06409.11 KND93428.1 - 0.24 10.4 4.0 0.37 9.8 4.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Peptidase_C78 PF07910.13 KND93429.1 - 4.5e-30 104.7 0.0 5.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C78 PF07910.13 KND93430.1 - 2.2e-07 30.6 0.0 2.3e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 TctC PF03401.14 KND93430.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Ham1p_like PF01725.16 KND93431.1 - 6.2e-58 195.8 0.0 7e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 KND93432.1 - 7.3e-12 46.0 1.3 3.9e-11 43.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KND93432.1 - 1.4e-06 28.8 0.2 2.2e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KND93432.1 - 2.7e-05 24.6 0.0 0.001 19.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KND93432.1 - 7.2e-05 23.1 0.4 0.00032 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND93432.1 - 0.00059 20.0 0.1 0.00094 19.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KND93432.1 - 0.0012 18.8 0.3 0.0021 18.0 0.1 1.5 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KND93432.1 - 0.0013 19.0 0.2 0.0062 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND93432.1 - 0.0014 19.1 0.1 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Hydin_ADK PF17213.3 KND93432.1 - 0.0014 18.9 0.1 0.011 16.1 0.0 2.0 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain ADK PF00406.22 KND93432.1 - 0.0028 17.8 0.0 0.0066 16.6 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.10 KND93432.1 - 0.0087 15.5 0.1 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 KND93432.1 - 0.014 15.2 1.0 0.02 14.7 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KND93432.1 - 0.014 15.7 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 KND93432.1 - 0.018 14.8 0.1 0.036 13.8 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KND93432.1 - 0.029 14.7 0.6 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND93432.1 - 0.03 14.3 0.0 0.067 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KND93432.1 - 0.063 12.9 0.1 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_2 PF07261.11 KND93432.1 - 0.08 12.7 0.5 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment AAA_24 PF13479.6 KND93432.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 KND93432.1 - 0.084 13.0 0.2 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family MeaB PF03308.16 KND93432.1 - 0.093 11.7 0.0 0.23 10.4 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Thymidylate_kin PF02223.17 KND93432.1 - 0.15 11.8 1.6 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Myosin_head PF00063.21 KND93433.1 - 2.5e-214 713.4 0.6 9.1e-214 711.6 0.6 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KND93433.1 - 7.9e-26 90.4 2.6 7.9e-26 90.4 2.6 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KND93433.1 - 1e-11 43.5 40.4 5.4e-05 22.6 2.8 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif DUF812 PF05667.11 KND93433.1 - 0.0008 18.4 22.2 0.0013 17.7 22.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Myosin_N PF02736.19 KND93433.1 - 0.003 17.3 0.2 0.0086 15.9 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KND93433.1 - 0.0058 16.9 0.0 0.021 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.6 KND93433.1 - 0.0068 16.1 14.2 0.0068 16.1 14.2 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) HSF_DNA-bind PF00447.17 KND93433.1 - 0.082 13.5 0.4 0.31 11.7 0.4 2.0 1 0 0 1 1 1 0 HSF-type DNA-binding Baculo_PEP_C PF04513.12 KND93433.1 - 0.13 12.3 3.7 0.52 10.3 3.7 2.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.6 KND93433.1 - 0.19 12.1 1.9 0.37 11.1 0.0 2.5 3 0 0 3 3 2 0 AAA ATPase domain Flagellin_N PF00669.20 KND93433.1 - 0.21 11.7 7.4 0.84 9.7 6.7 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Sec34 PF04136.15 KND93433.1 - 0.29 11.0 5.8 0.93 9.4 5.8 2.0 1 0 0 1 1 1 0 Sec34-like family Dna2 PF08696.11 KND93433.1 - 0.46 10.3 3.9 1.4 8.7 3.9 1.8 1 0 0 1 1 1 0 DNA replication factor Dna2 GAS PF13851.6 KND93433.1 - 0.58 9.5 28.2 0.045 13.1 14.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 KND93433.1 - 1 9.6 24.7 0.14 12.4 9.2 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 zf-C4H2 PF10146.9 KND93433.1 - 1.9 8.7 7.8 7 6.9 7.8 2.0 1 0 0 1 1 1 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 KND93433.1 - 2.5 8.3 27.8 4.8 7.4 4.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 KND93433.1 - 2.9 8.4 26.4 5.1 7.5 7.1 3.1 2 1 1 3 3 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 KND93433.1 - 5 6.9 26.6 23 4.7 22.7 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ING PF12998.7 KND93433.1 - 7.2 7.3 11.0 0.95 10.1 2.1 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding 2-Hacid_dh_C PF02826.19 KND93434.1 - 1.1e-51 174.8 0.0 1.6e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND93434.1 - 1.7e-37 128.1 0.1 2.2e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND93434.1 - 4.9e-05 23.5 0.2 0.00014 22.0 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KND93434.1 - 0.0013 18.3 0.0 0.0052 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 KND93434.1 - 0.0056 16.8 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KND93434.1 - 0.018 15.6 0.0 0.085 13.4 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain ACT PF01842.25 KND93434.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.8 1 0 0 1 1 1 0 ACT domain Oxidored_nitro PF00148.19 KND93434.1 - 0.056 12.2 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Serglycin PF04360.12 KND93435.1 - 0.23 11.4 4.5 0.46 10.4 4.5 1.5 1 0 0 1 1 1 0 Serglycin WAPL PF07814.13 KND93436.1 - 1.4e-54 185.4 0.0 1.8e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin FAA_hydro_N_2 PF18288.1 KND93436.1 - 0.021 15.2 0.6 0.072 13.5 0.6 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 RRM_1 PF00076.22 KND93437.1 - 2.6e-33 113.7 0.0 9.3e-16 57.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND93437.1 - 0.0025 17.4 0.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND93437.1 - 0.02 15.0 0.0 0.079 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 KND93437.1 - 0.022 14.4 1.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KND93437.1 - 0.026 14.5 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 KND93438.1 - 2.4e-57 190.8 3.7 1.3e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 KND93438.1 - 8.3e-20 70.2 0.1 2e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 TOM7 family zf-C2H2 PF00096.26 KND93439.1 - 5.3e-17 61.2 20.9 0.0001 22.6 1.0 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND93439.1 - 3.5e-13 49.3 18.4 2.2e-08 34.2 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND93439.1 - 1e-09 38.4 18.4 0.028 15.3 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 KND93439.1 - 0.007 16.7 11.8 0.32 11.4 0.4 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KND93439.1 - 0.12 12.5 5.0 0.18 11.9 0.1 2.5 1 1 1 2 2 2 0 Aberrant zinc-finger GAGA PF09237.11 KND93439.1 - 0.28 11.0 1.6 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.6 KND93439.1 - 0.45 10.6 12.0 6.8 6.8 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-LYAR PF08790.11 KND93439.1 - 0.51 10.3 5.9 10 6.1 0.3 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger CAML PF14963.6 KND93439.1 - 1.3 9.0 3.8 4 7.5 0.0 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Fer2 PF00111.27 KND93440.1 - 0.0091 15.9 0.7 0.016 15.2 0.7 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WD40 PF00400.32 KND93441.1 - 1.7e-30 104.6 19.7 0.00016 22.4 0.0 11.4 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND93441.1 - 1.8e-08 34.5 0.1 3.2 8.1 0.0 7.4 6 2 3 9 9 9 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND93441.1 - 0.0013 17.8 0.3 4.3 6.2 0.1 4.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Mub_B2 PF17966.1 KND93441.1 - 0.09 13.5 0.2 0.09 13.5 0.2 2.9 3 1 0 3 3 3 0 Mub B2-like domain SASA PF03629.18 KND93441.1 - 0.1 12.2 0.1 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate esterase, sialic acid-specific acetylesterase Epimerase PF01370.21 KND93442.1 - 3.9e-18 65.8 0.1 5e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KND93442.1 - 1.6e-09 37.3 0.4 2e-09 37.0 0.4 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KND93442.1 - 7.8e-09 35.7 2.2 9e-09 35.5 1.5 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KND93442.1 - 2.1e-08 34.0 0.0 0.00035 20.1 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KND93442.1 - 7.7e-07 28.9 0.2 1.2e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KND93442.1 - 5.8e-06 25.5 0.0 1e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KND93442.1 - 0.0012 18.0 0.1 0.022 13.9 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 KND93442.1 - 0.09 13.0 0.1 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 KND93442.1 - 0.15 12.2 0.4 0.56 10.3 0.4 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RF-1 PF00472.20 KND93444.1 - 7.4e-24 83.9 3.6 9.2e-24 83.6 3.0 1.4 1 1 0 1 1 1 1 RF-1 domain WDCP PF15390.6 KND93444.1 - 0.37 9.1 3.8 0.46 8.8 3.8 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family GcrA PF07750.11 KND93444.1 - 1.8 9.0 8.0 0.35 11.3 3.0 2.0 1 1 1 2 2 2 0 GcrA cell cycle regulator Actin PF00022.19 KND93445.1 - 1.3e-150 501.5 0.0 5.2e-150 499.6 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_L5_C PF00673.21 KND93446.1 - 1.9e-28 98.4 0.0 6.2e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KND93446.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 SQHop_cyclase_C PF13243.6 KND93447.1 - 7.8e-47 159.9 0.6 1.2e-44 152.8 0.5 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KND93447.1 - 2.4e-42 145.0 1.1 3.7e-36 124.7 0.1 3.1 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KND93447.1 - 1.1e-27 95.5 8.5 5.9e-10 38.7 0.2 5.7 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 KND93447.1 - 0.00041 19.5 0.1 0.0071 15.4 0.2 2.4 2 1 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 KND93447.1 - 0.081 12.2 0.3 1.4 8.1 0.0 3.1 3 1 0 3 3 3 0 Pectic acid lyase TP6A_N PF04406.14 KND93448.1 - 2.3e-22 78.7 0.8 7.1e-22 77.2 0.4 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase SBF PF01758.16 KND93449.1 - 2.3e-50 171.0 10.2 4.3e-50 170.1 10.2 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family HKR_ArcB_TM PF18415.1 KND93449.1 - 0.83 10.5 14.7 2.4 9.0 0.2 3.7 3 0 0 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain Peptidase_M48_N PF16491.5 KND93449.1 - 3 7.7 0.0 3 7.7 0.0 3.6 4 1 0 4 4 4 0 CAAX prenyl protease N-terminal, five membrane helices PLU-1 PF08429.11 KND93450.1 - 2e-111 372.5 12.0 1e-107 360.2 12.1 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KND93450.1 - 7.5e-43 145.6 0.3 1.6e-42 144.5 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KND93450.1 - 3.1e-21 75.8 0.0 8.3e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KND93450.1 - 1.1e-15 57.2 27.7 1.4e-09 37.7 3.4 3.5 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 KND93450.1 - 7.6e-15 54.6 0.6 1.7e-14 53.4 0.6 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 KND93450.1 - 2e-10 40.9 5.5 5.7e-10 39.4 5.5 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger Prok-JAB PF14464.6 KND93450.1 - 0.0023 17.7 0.1 0.0065 16.2 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-PHD-like PF15446.6 KND93450.1 - 0.0029 17.2 5.2 0.066 12.8 0.2 2.8 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KND93450.1 - 2.1 8.0 11.2 0.067 12.8 0.7 2.9 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 KND93450.1 - 2.4 8.1 20.1 2.4 8.1 0.2 3.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 KND93450.1 - 4.1 7.6 17.2 0.73 10.0 5.4 3.1 2 0 0 2 2 2 0 PHD-finger PAF-AH_p_II PF03403.13 KND93451.1 - 2.2e-35 121.9 0.0 2.3e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KND93451.1 - 0.00032 19.7 0.0 0.001 18.0 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KND93451.1 - 0.021 14.1 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KND93451.1 - 0.036 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_6 PF12697.7 KND93451.1 - 0.83 10.2 7.9 0.19 12.3 0.8 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 KND93452.1 - 1.6e-11 44.3 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND93452.1 - 1.6e-11 44.2 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND93452.1 - 8.1e-11 42.5 0.0 1.7e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND93452.1 - 7.2e-08 33.0 0.2 5e-07 30.3 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND93452.1 - 7.6e-08 33.0 0.2 9.2e-07 29.5 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND93452.1 - 0.00068 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KND93452.1 - 0.023 14.3 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_19 PF04672.12 KND93452.1 - 0.054 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase AAA PF00004.29 KND93453.1 - 4.2e-18 66.1 0.0 7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND93453.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KND93453.1 - 0.011 16.1 0.0 0.027 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.6 KND93453.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 KND93453.1 - 0.11 12.2 0.1 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ATPase PF06745.13 KND93453.1 - 0.18 11.1 0.2 0.73 9.1 0.2 1.8 2 0 0 2 2 2 0 KaiC Ank_4 PF13637.6 KND93454.1 - 1.1e-14 54.6 0.1 8.1e-08 32.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND93454.1 - 5.1e-14 52.1 0.4 8.3e-08 32.4 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND93454.1 - 6.9e-14 52.2 0.0 5e-11 43.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KND93454.1 - 7.3e-09 35.7 0.5 4e-05 23.9 0.8 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 KND93454.1 - 8.1e-09 35.0 0.0 0.00016 21.8 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1110 PF06533.12 KND93454.1 - 0.042 13.8 0.3 2.7 7.9 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1110) DUF4120 PF13496.6 KND93454.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) GATase_4 PF13230.6 KND93455.1 - 1.5e-15 56.9 0.1 8.3e-14 51.1 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 KND93455.1 - 3.2e-09 37.1 0.0 5.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain SoxD PF04267.12 KND93455.1 - 0.18 11.9 1.4 3.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family WD40 PF00400.32 KND93456.1 - 2.2e-11 44.1 8.4 0.0016 19.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND93456.1 - 0.00013 22.2 0.3 3.6 7.9 0.0 5.0 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain CREPT PF16566.5 KND93456.1 - 0.027 14.6 0.1 0.052 13.7 0.1 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Heme_oxygenase PF01126.20 KND93457.1 - 4.3e-09 36.4 0.0 1.7e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Heme oxygenase GSHPx PF00255.19 KND93459.1 - 1.3e-41 140.5 0.0 1.7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KND93459.1 - 0.0055 16.6 0.0 0.0087 16.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KND93459.1 - 0.03 14.0 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Redoxin F-box PF00646.33 KND93461.1 - 0.00037 20.3 0.4 0.0011 18.8 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KND93461.1 - 0.00052 19.8 0.1 0.0011 18.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like polyprenyl_synt PF00348.17 KND93463.1 - 1.9e-20 73.0 0.0 1.1e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KND93463.1 - 1.9e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ANTAR PF03861.14 KND93463.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 ANTAR domain Coleoptericin PF06286.11 KND93464.1 - 0.08 13.1 0.0 0.087 12.9 0.0 1.1 1 0 0 1 1 1 0 Coleoptericin FAD_binding_3 PF01494.19 KND93465.1 - 5.1e-10 39.1 2.1 0.00028 20.3 0.8 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KND93465.1 - 9.5e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KND93465.1 - 2.3e-05 23.7 0.3 0.00038 19.7 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KND93465.1 - 2.3e-05 23.8 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND93465.1 - 6.2e-05 22.7 0.2 0.00069 19.3 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND93465.1 - 7.5e-05 21.6 0.2 0.096 11.4 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 KND93465.1 - 0.0032 16.8 0.0 0.047 13.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KND93465.1 - 0.036 13.1 0.5 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 KND93465.1 - 0.12 12.9 0.1 6.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Polbeta PF18765.1 KND93466.1 - 0.00069 19.6 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 KND93466.1 - 0.01 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain RNA_pol_Rpc4 PF05132.14 KND93467.1 - 1.5e-33 116.3 0.1 1.5e-33 116.3 0.1 3.1 3 1 0 3 3 3 1 RNA polymerase III RPC4 Keratin_2_head PF16208.5 KND93467.1 - 0.019 15.1 15.6 0.019 15.1 15.6 1.7 2 0 0 2 2 2 0 Keratin type II head UreD PF01774.17 KND93468.1 - 2.9e-72 243.0 0.0 3.5e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein DUF1148 PF06618.11 KND93468.1 - 0.075 13.2 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) Mito_carr PF00153.27 KND93469.1 - 7.4e-71 234.2 1.1 2e-25 88.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KND93469.1 - 2e-16 60.2 3.2 2.5e-08 34.3 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 KND93469.1 - 4e-16 57.3 7.2 2.9e-07 29.6 0.2 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KND93469.1 - 2.2e-14 52.1 4.5 1.6e-06 27.6 0.1 5.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 KND93469.1 - 3.3e-11 42.8 2.0 0.22 11.4 0.1 5.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 KND93469.1 - 4.6e-10 38.5 4.4 1.2e-05 24.6 0.2 4.5 4 0 0 4 4 4 3 EF hand Dockerin_1 PF00404.18 KND93469.1 - 0.045 13.9 0.0 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain Cyclin_N PF00134.23 KND93470.1 - 1.1e-43 148.0 0.2 2.3e-43 147.0 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KND93470.1 - 4.8e-35 120.2 0.0 1e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.22 KND93471.1 - 3.4e-49 167.6 0.0 1.4e-27 96.2 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KND93471.1 - 1.6e-39 135.4 0.0 6.7e-39 133.3 0.0 2.1 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KND93471.1 - 5.5e-30 104.4 0.1 9.8e-22 77.2 0.0 4.8 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KND93471.1 - 1.3e-11 44.7 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KND93471.1 - 0.044 13.1 0.0 8.6 5.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 KND93471.1 - 0.18 11.3 2.1 5.8 6.5 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KND93471.1 - 0.45 10.7 1.3 1.8 8.7 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain PQ-loop PF04193.14 KND93472.1 - 4.9e-32 109.5 11.2 9.3e-16 57.4 3.6 2.5 2 0 0 2 2 2 2 PQ loop repeat MFS_1 PF07690.16 KND93473.1 - 1e-29 103.6 44.5 1e-29 103.6 44.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3593 PF12159.8 KND93474.1 - 0.037 14.1 1.7 0.076 13.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) Zn_clus PF00172.18 KND93475.1 - 0.00086 19.4 12.3 0.0015 18.6 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KND93475.1 - 0.044 13.3 0.1 0.044 13.3 0.1 2.3 3 0 0 3 3 3 0 Histone chaperone domain CHZ Abhydrolase_3 PF07859.13 KND93476.1 - 9.3e-09 35.4 1.2 2.3e-07 30.9 1.2 2.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND93476.1 - 8.3e-07 29.8 3.4 1.2e-06 29.3 3.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND93476.1 - 0.0012 18.4 0.0 0.025 14.1 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 KND93476.1 - 0.0042 17.2 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 KND93476.1 - 0.01 15.1 0.0 0.37 10.0 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 KND93476.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.8 KND93476.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 KND93476.1 - 0.21 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) IGR PF09597.10 KND93477.1 - 2.2e-25 88.5 0.1 3.9e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif DUF4661 PF15576.6 KND93477.1 - 0.04 13.8 0.0 0.062 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PhoLip_ATPase_C PF16212.5 KND93478.1 - 2.8e-49 168.1 4.8 2.8e-49 168.1 4.8 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND93478.1 - 2.8e-16 58.9 1.3 5.8e-16 57.9 1.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KND93478.1 - 4.4e-13 50.0 0.3 1.1e-06 29.1 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND93478.1 - 5.8e-08 32.5 0.1 0.004 16.7 0.0 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 KND93478.1 - 1.3e-06 28.4 0.0 9.2e-05 22.5 0.0 3.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KND93478.1 - 0.00096 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec16_C PF12931.7 KND93479.1 - 1.6e-110 369.5 0.1 2.2e-110 369.0 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KND93479.1 - 1e-30 106.7 0.0 3.9e-30 104.9 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KND93479.1 - 3.6e-14 53.5 14.1 3.6e-14 53.5 14.1 4.8 4 0 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Nup96 PF12110.8 KND93479.1 - 0.11 11.5 0.0 0.36 9.9 0.0 1.8 2 0 0 2 2 2 0 Nuclear protein 96 Glyco_hydro_63 PF03200.16 KND93480.1 - 4.8e-141 470.9 4.1 5.8e-141 470.6 0.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KND93480.1 - 1.7e-48 165.7 0.0 2.5e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KND93480.1 - 0.0012 17.8 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Trehalase MnmE_helical PF12631.7 KND93482.1 - 1.6e-29 103.6 0.1 1.9e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KND93482.1 - 4.3e-24 85.1 0.0 8.5e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KND93482.1 - 3.7e-18 65.7 0.0 7.4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND93482.1 - 5e-05 22.9 0.0 0.00011 21.8 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KND93482.1 - 0.0024 17.9 0.0 0.0099 16.0 0.0 1.9 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KND93482.1 - 0.0042 17.0 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 KND93482.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KND93482.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Proteasome PF00227.26 KND93483.1 - 3.5e-49 166.9 0.1 4.3e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KND93483.1 - 4.7e-11 42.1 0.2 7.8e-11 41.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Hus1 PF04005.12 KND93484.1 - 7.4e-82 274.7 0.0 9e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein SOG2 PF10428.9 KND93485.1 - 0.092 11.9 10.9 0.1 11.8 10.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 KND93485.1 - 0.44 10.4 4.6 0.52 10.2 4.6 1.1 1 0 0 1 1 1 0 SPX domain FH2 PF02181.23 KND93486.1 - 1.9e-85 287.2 4.8 3.9e-85 286.2 4.8 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.13 KND93486.1 - 4.3e-62 209.0 0.1 1.5e-61 207.3 0.1 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KND93486.1 - 6e-51 172.8 3.9 1.2e-50 171.9 1.4 2.8 2 1 1 3 3 3 1 Diaphanous FH3 Domain SNRNP27 PF08648.12 KND93487.1 - 1.3e-29 102.0 1.0 2.9e-29 100.9 1.0 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Peptidase_M19 PF01244.21 KND93488.1 - 2.5e-100 335.8 0.0 3.1e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GMC_oxred_N PF00732.19 KND93489.1 - 4.7e-51 173.9 0.0 6.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND93489.1 - 3.9e-34 118.3 0.0 5.9e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND93489.1 - 1.7e-05 24.1 1.1 0.017 14.2 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KND93489.1 - 0.0014 17.9 0.6 0.0024 17.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KND93489.1 - 0.0027 16.8 0.1 0.0052 15.9 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KND93489.1 - 0.017 14.4 0.1 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND93489.1 - 0.025 14.2 2.4 0.067 12.8 2.4 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND93489.1 - 0.032 13.5 0.1 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND93489.1 - 0.035 14.3 0.5 0.098 12.9 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Catalase PF00199.19 KND93490.1 - 3.7e-147 490.4 0.0 6.1e-99 331.7 0.0 2.0 1 1 1 2 2 2 2 Catalase Catalase-rel PF06628.12 KND93490.1 - 8.8e-14 51.5 0.0 2.1e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 KND93491.1 - 4e-12 45.7 40.0 7.2e-12 44.9 38.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KND93491.1 - 1e-08 35.1 8.2 1e-08 35.1 8.2 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Arylesterase PF01731.20 KND93492.1 - 4e-05 23.7 0.2 7.2e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Arylesterase S1-P1_nuclease PF02265.16 KND93495.1 - 8.2e-69 232.2 0.5 9.4e-69 232.0 0.5 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease F-box-like PF12937.7 KND93496.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like Acetyltransf_3 PF13302.7 KND93497.1 - 2.1e-27 96.5 0.0 2.9e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND93497.1 - 6.3e-08 32.9 0.0 8.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KND93497.1 - 9.7e-05 22.5 0.0 0.00012 22.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidase PF01425.21 KND93498.1 - 6.2e-101 338.6 0.0 3.3e-99 332.9 0.0 2.1 1 1 0 1 1 1 1 Amidase TauD PF02668.16 KND93499.1 - 3.1e-34 119.0 0.1 5.3e-34 118.2 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KND93499.1 - 6.1e-07 30.0 0.1 8.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF971) Alk_phosphatase PF00245.20 KND93500.1 - 3.2e-67 227.3 0.0 6.1e-67 226.4 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 KND93500.1 - 5.6e-07 29.5 0.0 9.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KND93500.1 - 9.9e-07 28.4 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KND93500.1 - 0.0021 16.7 0.3 0.004 15.8 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KND93500.1 - 0.0043 16.5 0.7 0.18 11.2 0.1 2.8 3 0 0 3 3 3 1 Metalloenzyme superfamily DUF1501 PF07394.12 KND93500.1 - 0.044 12.8 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CutC PF03932.14 KND93501.1 - 3.2e-31 108.4 0.1 9.8e-31 106.8 0.1 1.6 1 1 0 1 1 1 1 CutC family Septin PF00735.18 KND93502.1 - 3.6e-115 384.1 0.3 5.5e-115 383.5 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND93502.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND93502.1 - 4.8e-06 26.6 2.1 1.5e-05 25.0 0.1 2.5 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KND93502.1 - 1.7e-05 24.4 4.6 7e-05 22.4 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KND93502.1 - 0.0016 18.7 1.0 0.0046 17.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 KND93502.1 - 0.0028 17.8 0.1 0.0062 16.7 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 KND93502.1 - 0.0037 16.8 0.1 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 KND93502.1 - 0.0054 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family KAP_NTPase PF07693.14 KND93502.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Casc1_N PF15927.5 KND93502.1 - 0.013 15.2 10.6 0.035 13.8 10.6 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 KND93502.1 - 0.014 15.0 0.6 0.049 13.2 0.5 1.9 2 1 0 2 2 1 0 Ras family IIGP PF05049.13 KND93502.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 KND93502.1 - 0.018 14.8 0.5 0.048 13.4 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KND93502.1 - 0.02 14.4 0.2 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KND93502.1 - 0.022 15.3 0.4 0.076 13.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KND93502.1 - 0.027 14.9 1.2 0.062 13.7 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KND93502.1 - 0.049 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 KND93502.1 - 0.051 12.6 0.5 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 KND93502.1 - 0.059 14.0 1.1 0.059 14.0 1.1 2.5 3 1 1 4 4 1 0 FOXP coiled-coil domain RNA_helicase PF00910.22 KND93502.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Val_tRNA-synt_C PF10458.9 KND93502.1 - 0.12 12.7 0.6 0.12 12.7 0.6 2.6 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PduV-EutP PF10662.9 KND93502.1 - 0.18 11.5 1.3 4.8 6.9 0.4 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KND93502.1 - 0.48 10.5 7.4 3.6 7.6 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 KND93502.1 - 0.73 10.4 7.4 2.8 8.5 0.3 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 KND93502.1 - 2.2 8.0 7.0 19 5.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KND93503.1 - 1e-36 124.3 32.9 6.4e-07 30.0 0.1 12.8 15 0 0 15 15 15 7 WD domain, G-beta repeat Utp12 PF04003.12 KND93503.1 - 5.3e-24 84.6 0.0 8.5e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KND93503.1 - 1.1e-17 64.1 0.0 0.0045 17.3 0.0 9.1 4 2 5 11 11 11 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND93503.1 - 2.9e-06 26.5 0.3 2.6 6.9 0.0 5.3 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND93503.1 - 1.7e-05 24.8 1.8 0.079 12.8 0.1 4.7 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KND93503.1 - 0.00037 19.9 0.0 0.13 11.6 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 KND93503.1 - 0.0092 15.3 0.1 16 4.7 0.0 3.9 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KND93503.1 - 0.013 14.1 2.4 2 7.0 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 KND93503.1 - 0.15 12.6 0.7 54 4.4 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Questin_oxidase PF14027.6 KND93504.1 - 6.9e-88 295.4 2.6 8.3e-88 295.2 2.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAP PF00956.18 KND93505.1 - 8.9e-26 90.7 13.4 5.5e-25 88.1 6.4 2.3 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) cwf18 PF08315.12 KND93505.1 - 0.014 16.0 4.3 0.014 16.0 4.3 1.9 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor DUF3042 PF11240.8 KND93505.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3042) MscS_TM PF12794.7 KND93505.1 - 0.54 9.1 1.7 0.89 8.3 1.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Presenilin PF01080.17 KND93505.1 - 4.7 5.9 3.9 6.3 5.5 3.9 1.2 1 0 0 1 1 1 0 Presenilin Asparaginase PF00710.20 KND93506.1 - 1.5e-56 191.0 0.0 2.1e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KND93506.1 - 2.6e-24 85.6 0.0 4.7e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KND93506.1 - 2.7e-16 59.9 0.1 2e-08 34.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND93506.1 - 5.3e-07 29.5 0.0 0.004 17.5 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KND93506.1 - 9.4e-06 26.1 0.0 0.00019 21.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KND93506.1 - 0.00013 22.3 0.0 0.072 13.6 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KND93506.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) USP7_ICP0_bdg PF12436.8 KND93507.1 - 2.2e-86 289.1 0.4 1.3e-84 283.3 0.1 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KND93507.1 - 2.2e-71 239.8 3.8 1.4e-68 230.7 0.9 3.8 2 1 1 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KND93507.1 - 3e-47 161.3 2.0 5.1e-47 160.5 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND93507.1 - 1.6e-21 77.3 0.8 4.1e-21 75.9 0.2 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KND93507.1 - 2.9e-07 30.6 0.0 1.3e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 MATH domain YukD PF08817.10 KND93507.1 - 0.0012 19.5 0.1 4.2 8.1 0.0 3.4 3 0 0 3 3 3 2 WXG100 protein secretion system (Wss), protein YukD BAF250_C PF12031.8 KND93508.1 - 0.065 12.5 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa BCDHK_Adom3 PF10436.9 KND93509.1 - 4.6e-45 153.4 0.0 1e-44 152.2 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KND93509.1 - 1e-06 29.2 0.0 4e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KND93509.1 - 0.032 14.0 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 KND93509.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 KND93510.1 - 0.0032 18.0 0.0 0.0062 17.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AA_permease PF00324.21 KND93511.1 - 4.6e-132 441.0 50.0 3.3e-123 411.8 32.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KND93511.1 - 6.3e-27 94.5 49.4 3e-25 88.9 49.4 2.1 1 1 0 1 1 1 1 Amino acid permease SVM_signal PF12113.8 KND93511.1 - 1.4 8.9 6.3 0.5 10.3 1.8 2.6 2 0 0 2 2 2 0 SVM protein signal sequence Acyl-CoA_dh_1 PF00441.24 KND93512.1 - 7.1e-27 94.5 0.3 1.3e-26 93.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KND93512.1 - 1.9e-20 72.9 0.0 3.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KND93512.1 - 6.6e-14 52.5 0.1 1.6e-13 51.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KND93512.1 - 1.3e-10 41.7 0.1 1.3e-10 41.7 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.20 KND93513.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KND93513.1 - 0.038 13.9 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.12 KND93513.1 - 0.042 13.5 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.20 KND93513.1 - 0.05 13.7 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain ARL6IP6 PF15062.6 KND93513.1 - 0.14 12.3 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix DUF1769 PF08588.10 KND93514.1 - 7.2e-28 96.6 0.5 1.6e-27 95.4 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) Peptidase_A4 PF01828.17 KND93515.1 - 1.5e-32 112.8 0.6 2.1e-32 112.3 0.6 1.2 1 0 0 1 1 1 1 Peptidase A4 family APCDDC PF14921.6 KND93515.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 Lustrin_cystein PF14625.6 KND93516.1 - 2.1 8.8 10.4 13 6.2 10.1 2.1 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain FYDLN_acid PF09538.10 KND93517.1 - 0.051 14.2 0.7 0.15 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Macoilin PF09726.9 KND93517.1 - 0.16 10.5 4.6 0.24 9.9 4.6 1.1 1 0 0 1 1 1 0 Macoilin family Polysacc_synt_4 PF04669.13 KND93518.1 - 4.9e-21 75.1 0.6 2e-19 69.9 0.6 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 KND93518.1 - 0.028 14.1 1.0 0.061 13.0 1.0 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain MFS_1 PF07690.16 KND93520.1 - 5.2e-23 81.5 27.6 5.2e-23 81.5 27.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.6 KND93521.1 - 1.9e-26 93.7 0.1 3.9e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KND93521.1 - 4.6e-13 49.3 0.1 8.3e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND93521.1 - 5.5e-07 29.5 0.1 1.5e-05 24.8 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.15 KND93521.1 - 0.095 12.6 0.2 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus GIT_CC PF16559.5 KND93522.1 - 0.063 13.2 1.5 0.11 12.4 1.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cwf_Cwc_15 PF04889.12 KND93522.1 - 0.099 12.4 0.5 0.14 11.9 0.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP5 PF08321.12 KND93523.1 - 5.5e-33 113.1 1.6 6.3e-33 112.9 0.4 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 KND93523.1 - 1.8e-30 107.0 0.1 3e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KND93523.1 - 1.5e-18 65.7 1.0 1.6e-05 24.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND93523.1 - 3.4e-13 48.6 0.7 0.0033 17.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND93523.1 - 6.1e-11 41.8 1.3 0.0019 17.8 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 KND93523.1 - 4.5e-07 29.6 0.9 0.13 12.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KND93523.1 - 1.6e-05 25.0 0.7 0.19 12.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KND93523.1 - 2.2e-05 24.9 0.1 0.0084 16.6 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KND93523.1 - 0.0002 21.4 0.0 0.0012 19.0 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND93523.1 - 0.00057 20.5 0.1 3.7 8.6 0.0 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND93523.1 - 0.0008 20.0 0.8 0.18 12.5 1.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 KND93523.1 - 0.012 14.9 0.1 0.14 11.4 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KND93523.1 - 0.12 11.8 0.0 24 4.5 0.0 2.7 2 0 0 2 2 2 0 SHNi-TPR Kin17_mid PF10357.9 KND93525.1 - 3.7e-52 175.5 1.0 3.7e-52 175.5 1.0 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KND93525.1 - 0.00013 22.3 3.3 0.00043 20.6 3.3 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND93525.1 - 0.00021 21.5 1.8 0.00021 21.5 1.8 2.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KND93525.1 - 0.0069 16.7 2.1 0.012 16.0 0.3 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Spt4 PF06093.13 KND93526.1 - 1.2e-31 108.6 0.2 1.5e-31 108.3 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Serglycin PF04360.12 KND93527.1 - 0.0042 17.0 1.6 0.0042 17.0 1.6 1.1 1 0 0 1 1 1 1 Serglycin DUF572 PF04502.13 KND93528.1 - 1.1e-67 229.0 8.9 1.3e-67 228.8 8.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) RNA_pol_N PF01194.17 KND93528.1 - 0.17 12.2 1.5 7.8 6.9 0.3 2.6 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Methyltransf_25 PF13649.6 KND93529.1 - 0.0087 16.7 0.0 0.0092 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND93529.1 - 0.036 14.7 0.0 0.04 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain FAM177 PF14774.6 KND93529.1 - 0.17 12.2 0.3 0.23 11.8 0.3 1.3 1 0 0 1 1 1 0 FAM177 family Pyr_redox_2 PF07992.14 KND93530.1 - 5.2e-33 114.5 0.4 6.1e-33 114.3 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND93530.1 - 2.4e-09 37.6 1.0 5.6e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND93530.1 - 2e-05 23.9 1.7 0.019 14.1 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NTPase_I-T PF01931.18 KND93530.1 - 0.017 14.9 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF84 DAO PF01266.24 KND93530.1 - 0.19 11.3 1.5 42 3.6 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Es2 PF09751.9 KND93531.1 - 8.2e-103 345.4 10.1 8.2e-103 345.4 10.1 2.0 2 0 0 2 2 2 1 Nuclear protein Es2 ABC1 PF03109.16 KND93531.1 - 1.6e-32 112.2 0.0 3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RRP36 PF06102.12 KND93532.1 - 5.5e-57 192.4 30.9 5.5e-57 192.4 30.9 2.0 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 MIF4G_like PF09088.11 KND93533.1 - 4.3e-75 251.7 0.0 7.1e-75 251.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KND93533.1 - 2.7e-67 227.0 0.0 3.8e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 MIF4G like Patatin PF01734.22 KND93534.1 - 1.9e-18 67.4 0.3 2e-17 64.1 0.2 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_12 PF13424.6 KND93534.1 - 1.3e-14 54.2 0.1 2.1e-07 31.1 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND93534.1 - 8.4e-13 47.8 1.8 4.8e-05 23.1 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.22 KND93534.1 - 9.2e-11 41.4 0.1 1.8e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 KND93534.1 - 2e-07 31.4 0.8 0.00089 19.7 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KND93534.1 - 0.00022 21.2 0.0 0.54 10.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KND93534.1 - 0.00026 21.6 0.7 1.5 9.9 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KND93534.1 - 0.00031 20.9 0.0 1.6 9.0 0.0 3.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KND93534.1 - 0.00041 20.2 0.2 3.6 7.8 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 KND93534.1 - 0.00048 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 KND93534.1 - 0.0025 17.8 0.0 0.83 9.9 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.6 KND93534.1 - 0.003 17.8 0.0 0.012 15.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain TPR_6 PF13174.6 KND93534.1 - 0.0047 17.5 0.4 11 6.9 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 KND93534.1 - 0.0057 16.8 0.0 14 6.1 0.1 3.7 3 0 0 3 3 3 0 PPR repeat AAA_16 PF13191.6 KND93534.1 - 0.0082 16.5 0.0 0.049 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain TPR_20 PF14561.6 KND93534.1 - 0.0088 16.4 1.7 1.4 9.3 0.1 3.2 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND93534.1 - 0.04 14.6 0.2 0.81 10.4 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SRP54 PF00448.22 KND93534.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CAF1A PF12253.8 KND93535.1 - 4.9e-21 74.7 2.7 4.9e-21 74.7 2.7 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Hamartin PF04388.12 KND93535.1 - 0.025 13.3 19.5 0.037 12.7 19.5 1.3 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 KND93535.1 - 0.21 11.3 20.8 0.38 10.4 20.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Raftlin PF15250.6 KND93535.1 - 2 7.1 14.8 3.4 6.3 14.8 1.4 1 0 0 1 1 1 0 Raftlin SLC12 PF03522.15 KND93535.1 - 7.9 5.4 15.0 12 4.8 15.0 1.5 1 0 0 1 1 1 0 Solute carrier family 12 NEMO PF11577.8 KND93536.1 - 0.047 13.7 0.4 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Pkinase PF00069.25 KND93537.1 - 6.9e-41 140.3 0.0 1.1e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93537.1 - 3e-26 92.3 0.0 4.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KND93537.1 - 1.7e-06 28.2 0.1 4e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KND93537.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND93537.1 - 0.037 13.9 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND93537.1 - 0.077 11.8 0.6 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KND93537.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Stm1_N PF09598.10 KND93537.1 - 5.4 7.9 7.7 0.33 11.8 1.4 2.3 2 0 0 2 2 2 0 Stm1 DUF4690 PF15756.5 KND93539.1 - 0.041 14.5 0.0 0.041 14.5 0.0 2.2 3 0 0 3 3 3 0 Small Novel Rich in Cartilage CYYR1 PF10873.8 KND93539.1 - 0.12 12.8 2.2 0.2 12.1 0.2 2.4 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF2613 PF11021.8 KND93539.1 - 2 8.6 6.1 5.1 7.3 6.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Cupin_8 PF13621.6 KND93540.1 - 2.7e-12 46.9 0.0 3.4e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain PAP2_3 PF14378.6 KND93540.1 - 0.011 15.5 0.1 0.014 15.1 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily DUF2826 PF11442.8 KND93540.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) NPCC PF08058.11 KND93541.1 - 4.4e-26 91.5 0.0 6.4e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component ERG2_Sigma1R PF04622.12 KND93543.1 - 4.9e-95 316.8 0.0 6.1e-95 316.5 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 KND93543.1 - 0.097 12.6 0.1 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein NmrA PF05368.13 KND93544.1 - 2.7e-80 269.3 0.0 3.5e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND93544.1 - 6.6e-07 29.4 0.0 1.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF2498 PF10692.9 KND93544.1 - 0.08 12.8 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2498) DUF3798 PF12683.7 KND93544.1 - 0.094 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Fcf1 PF04900.12 KND93545.1 - 1.4e-32 112.0 0.1 3.9e-32 110.6 0.1 1.8 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KND93545.1 - 3.1e-11 43.6 0.0 7.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 PIN like domain Fungal_trans PF04082.18 KND93545.1 - 7.9e-11 41.5 0.7 1.3e-10 40.7 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93545.1 - 4.1e-06 26.8 10.0 8.3e-06 25.8 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4080 PF13311.6 KND93545.1 - 0.13 12.5 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Rep_fac_C PF08542.11 KND93546.1 - 2.2e-22 79.2 0.0 6.5e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KND93546.1 - 3.3e-12 46.5 0.0 1.1e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 KND93546.1 - 1.6e-11 44.8 0.0 3.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KND93546.1 - 1.4e-06 28.4 0.0 2.9e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND93546.1 - 6.8e-06 26.6 0.0 0.00031 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 KND93546.1 - 3.3e-05 23.7 0.0 8.6e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KND93546.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND93546.1 - 0.00026 21.3 0.1 0.2 11.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KND93546.1 - 0.00028 20.7 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KND93546.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 KND93546.1 - 0.0029 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 KND93546.1 - 0.0039 16.6 0.1 0.04 13.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 KND93546.1 - 0.0044 17.3 0.0 0.016 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 KND93546.1 - 0.0071 15.8 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 KND93546.1 - 0.0083 15.1 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KND93546.1 - 0.0098 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KND93546.1 - 0.01 15.6 0.1 0.44 10.3 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 KND93546.1 - 0.016 15.6 0.1 0.054 13.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KND93546.1 - 0.019 15.0 0.0 0.067 13.2 0.0 2.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KND93546.1 - 0.021 14.4 0.1 0.17 11.4 0.1 2.3 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 KND93546.1 - 0.026 14.2 0.0 0.075 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KND93546.1 - 0.027 13.9 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 KND93546.1 - 0.043 13.7 0.5 0.13 12.2 0.1 2.0 2 1 0 3 3 2 0 NTPase AAA_30 PF13604.6 KND93546.1 - 0.057 13.1 0.1 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 KND93546.1 - 0.073 13.0 0.2 0.75 9.7 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III DER1 PF04511.15 KND93548.1 - 3.7e-24 85.7 6.6 4.3e-24 85.5 6.6 1.0 1 0 0 1 1 1 1 Der1-like family NAP PF00956.18 KND93549.1 - 2.9e-99 331.6 5.0 2.9e-99 331.6 5.0 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Eisosome1 PF12757.7 KND93550.1 - 3.4e-43 146.9 13.8 3.4e-43 146.9 13.8 5.1 3 2 0 3 3 3 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 KND93551.1 - 3.3e-42 145.0 0.0 4.8e-42 144.5 0.0 1.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KND93551.1 - 1.6e-05 24.6 0.0 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 KND93551.1 - 0.00015 20.8 0.1 0.011 14.6 0.0 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 KND93551.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KND93551.1 - 0.19 11.6 0.1 0.57 10.0 0.1 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KND93551.1 - 0.22 11.8 0.3 1.3 9.4 0.0 2.1 2 1 0 2 2 2 0 Rit1 DUSP-like domain Pkinase PF00069.25 KND93552.1 - 2.3e-62 210.8 0.0 2.9e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93552.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93552.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND93552.1 - 0.21 10.9 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KND93552.1 - 0.23 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Frag1 PF10277.9 KND93553.1 - 1.5e-43 148.9 16.5 1.7e-43 148.7 16.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 KND93553.1 - 0.013 14.2 4.9 0.021 13.5 4.9 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 GWT1 PF06423.12 KND93553.1 - 1.9 8.6 4.7 3 7.9 4.5 1.8 1 1 0 1 1 1 0 GWT1 ABC_tran PF00005.27 KND93554.1 - 2.6e-10 40.9 0.0 8.9e-10 39.2 0.0 1.9 3 0 0 3 3 3 1 ABC transporter AAA_23 PF13476.6 KND93554.1 - 0.00026 21.6 0.0 0.00043 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND93554.1 - 0.00054 20.4 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 KND93554.1 - 0.0045 16.4 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KND93554.1 - 0.016 15.0 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND93554.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 KND93554.1 - 0.11 11.5 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_25 PF13649.6 KND93556.1 - 1.1e-15 58.1 0.0 2.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND93556.1 - 3.1e-15 56.7 0.1 1.2e-14 54.9 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND93556.1 - 1.1e-12 48.4 0.0 2.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND93556.1 - 1.5e-10 41.2 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND93556.1 - 1.6e-08 34.5 0.0 6.3e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND93556.1 - 7.4e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 KND93556.1 - 1.6e-05 24.8 0.0 0.00051 19.9 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 KND93556.1 - 6.5e-05 23.9 0.1 0.00025 22.0 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KND93556.1 - 0.00069 18.9 0.0 0.47 9.6 0.0 2.2 1 1 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.14 KND93556.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF3298 PF11738.8 KND93556.1 - 0.036 15.1 0.6 1.1 10.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Methyltransf_16 PF10294.9 KND93556.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_20 PF12147.8 KND93556.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DUF3419 PF11899.8 KND93556.1 - 0.043 13.0 0.1 0.11 11.7 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3419) Methyltransf_32 PF13679.6 KND93556.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Questin_oxidase PF14027.6 KND93558.1 - 5.8e-70 236.5 2.4 7.2e-70 236.2 2.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like CMD PF02627.20 KND93558.1 - 0.066 13.3 0.5 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Lipase_GDSL_2 PF13472.6 KND93559.1 - 1.5e-09 38.5 0.8 2.8e-09 37.6 0.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND93559.1 - 1.2e-06 28.6 0.0 2.2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KND93559.1 - 0.00094 19.4 0.0 0.0021 18.2 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF1996 PF09362.10 KND93560.1 - 4.2e-85 285.5 0.8 5.9e-85 285.0 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fungal_trans PF04082.18 KND93561.1 - 1.9e-09 36.9 0.2 3.3e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93561.1 - 7.1e-05 22.9 7.3 7.1e-05 22.9 7.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3367 PF11847.8 KND93561.1 - 0.011 13.7 0.0 0.018 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Oxidored_q2 PF00420.24 KND93561.1 - 0.03 13.9 0.1 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DAO PF01266.24 KND93562.1 - 1.4e-67 228.8 2.1 1.6e-67 228.6 2.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND93562.1 - 1.1e-05 25.9 0.1 0.017 15.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND93562.1 - 2.5e-05 24.4 0.2 7.3e-05 22.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND93562.1 - 0.00047 19.5 0.7 0.0032 16.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 KND93562.1 - 0.0029 16.3 0.1 0.68 8.4 0.1 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 KND93562.1 - 0.0065 15.7 0.2 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KND93562.1 - 0.0083 15.3 0.7 0.014 14.5 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GMC_oxred_N PF00732.19 KND93562.1 - 0.0088 15.4 0.2 2.1 7.6 0.1 2.1 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.14 KND93562.1 - 0.013 14.4 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 KND93562.1 - 0.025 13.4 1.0 0.24 10.2 0.1 2.0 2 0 0 2 2 2 0 MCRA family NAD_binding_9 PF13454.6 KND93562.1 - 0.15 12.0 0.3 0.58 10.1 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Prenylcys_lyase PF07156.14 KND93562.1 - 0.23 10.5 0.0 0.34 10.0 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase HAD_2 PF13419.6 KND93563.1 - 1.5e-20 74.0 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND93563.1 - 3.5e-07 30.7 0.1 7.8e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KND93563.1 - 4.6e-06 26.5 0.0 0.0046 16.7 0.0 2.1 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 KND93563.1 - 8.1e-05 22.6 0.1 0.00014 21.9 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Rit1_C PF17184.4 KND93564.1 - 5.7e-47 160.4 0.0 7.7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KND93564.1 - 2.4e-33 114.7 0.0 3.7e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain MARVEL PF01284.23 KND93565.1 - 0.00032 20.7 16.1 0.00052 20.1 16.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF5134 PF17197.4 KND93565.1 - 0.018 15.0 1.0 0.024 14.6 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF2304 PF10066.9 KND93565.1 - 0.47 10.7 3.2 0.88 9.8 3.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) COX8 PF02285.15 KND93565.1 - 6.7 6.7 7.0 6.8 6.6 2.6 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII MFS_1 PF07690.16 KND93566.1 - 2.1e-42 145.3 42.1 2.1e-42 145.3 42.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93566.1 - 1.1e-16 60.8 8.9 1.1e-16 60.8 8.9 3.7 2 1 2 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 KND93566.1 - 9.7e-07 27.6 17.6 4.7e-06 25.3 15.9 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyoxalase_2 PF12681.7 KND93567.1 - 1.3e-11 44.5 0.0 1.5e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 KND93567.1 - 1.8e-10 41.1 0.0 3.6e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KND93567.1 - 0.00018 22.3 0.7 0.00023 21.9 0.7 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KND93567.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily bZIP_2 PF07716.15 KND93568.1 - 0.0034 17.4 11.0 0.0066 16.5 11.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KND93568.1 - 0.049 13.7 8.7 0.12 12.5 8.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF4692 PF15763.5 KND93568.1 - 0.83 10.1 9.5 0.7 10.4 8.1 1.5 1 1 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) CDC45 PF02724.14 KND93568.1 - 2.1 6.5 11.8 2.8 6.1 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KND93568.1 - 3.2 6.4 7.2 3.8 6.2 7.2 1.2 1 0 0 1 1 1 0 Presenilin adh_short PF00106.25 KND93569.1 - 2.5e-20 72.8 0.0 2.5e-18 66.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND93569.1 - 2.1e-10 40.6 0.0 2.3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND93569.1 - 5.1e-07 29.8 0.1 7.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KND93569.1 - 0.18 11.9 0.2 0.63 10.1 0.1 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Med5 PF08689.10 KND93570.1 - 9.2e-95 318.5 0.0 1e-93 315.0 0.0 2.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 TRAP_alpha PF03896.16 KND93571.1 - 8.5e-11 41.6 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.23 KND93572.1 - 6.9e-58 196.0 0.0 1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 KND93572.1 - 5.1e-08 33.1 11.4 5.1e-08 33.1 11.4 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND93572.1 - 9.7e-08 31.8 8.3 9.7e-08 31.8 8.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND93572.1 - 1.6e-06 27.8 12.7 1.6e-06 27.8 12.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND93572.1 - 9e-06 25.5 10.9 9e-06 25.5 10.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KND93572.1 - 6.4e-05 23.3 0.0 0.00026 21.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 KND93572.1 - 9.9e-05 22.6 8.4 0.00025 21.3 8.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND93572.1 - 0.00011 21.9 8.5 0.00028 20.7 8.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KND93572.1 - 0.0011 18.8 11.3 0.0011 18.8 11.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND93572.1 - 0.0017 18.3 5.4 0.0017 18.3 5.4 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-P11 PF03854.14 KND93572.1 - 0.14 11.8 7.6 1 9.1 7.6 2.3 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 KND93572.1 - 0.18 11.6 4.6 0.54 10.1 4.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KND93572.1 - 0.62 9.7 10.8 0.79 9.4 7.9 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KND93572.1 - 0.79 9.9 13.0 1.4 9.2 10.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KND93572.1 - 1.7 8.8 5.5 5.3 7.2 5.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 TBCA PF02970.16 KND93572.1 - 8.8 6.7 7.0 23 5.4 0.1 3.7 2 1 1 3 3 3 0 Tubulin binding cofactor A CN_hydrolase PF00795.22 KND93573.1 - 1.4e-13 50.8 0.0 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase DKCLD PF08068.12 KND93575.1 - 1.3e-34 118.0 0.3 9.9e-33 112.0 0.3 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KND93575.1 - 1e-23 84.4 0.2 1e-20 74.6 0.2 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KND93575.1 - 1.8e-22 79.3 1.1 3.3e-22 78.4 1.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KND93575.1 - 8.2e-21 73.8 0.5 1.4e-20 73.0 0.5 1.4 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KND93575.1 - 0.00069 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Sec2p PF06428.11 KND93577.1 - 4.1e-12 45.9 9.9 5.1e-12 45.6 4.6 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p GOLGA2L5 PF15070.6 KND93577.1 - 0.0095 14.6 2.0 0.0095 14.6 2.0 2.1 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 DUF4763 PF15960.5 KND93577.1 - 0.022 14.1 4.4 0.28 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) BST2 PF16716.5 KND93577.1 - 0.024 15.2 7.1 0.93 10.1 0.4 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 KND93577.1 - 0.027 14.7 15.5 0.12 12.6 6.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 KND93577.1 - 0.044 14.4 11.2 0.92 10.2 1.9 3.1 2 1 1 3 3 3 0 SlyX HR1 PF02185.16 KND93577.1 - 0.057 13.5 1.6 0.057 13.5 1.6 3.1 3 1 1 4 4 4 0 Hr1 repeat Casein PF00363.18 KND93577.1 - 0.065 13.6 0.7 0.12 12.7 0.7 1.5 1 0 0 1 1 1 0 Casein OCD_Mu_crystall PF02423.15 KND93577.1 - 0.096 11.6 1.1 0.17 10.8 1.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family BLOC1_2 PF10046.9 KND93577.1 - 0.19 12.0 2.5 0.53 10.6 0.4 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 KND93577.1 - 0.36 11.0 1.3 6.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Atg14 PF10186.9 KND93577.1 - 0.97 8.5 11.2 0.65 9.0 0.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3138 PF11336.8 KND93577.1 - 2 7.0 7.2 2.9 6.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2076 PF09849.9 KND93577.1 - 2.2 8.3 9.6 5.4 7.0 9.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) HrpB7 PF09486.10 KND93577.1 - 2.2 8.6 29.3 2 8.8 8.4 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) MbeD_MobD PF04899.12 KND93577.1 - 2.4 8.3 8.3 5.5 7.2 0.8 2.7 2 1 1 3 3 3 0 MbeD/MobD like HAUS-augmin3 PF14932.6 KND93577.1 - 2.8 7.4 9.1 4.4 6.8 2.4 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 KND93577.1 - 3.6 8.3 6.4 2 9.1 0.4 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 KND93577.1 - 3.7 7.9 14.2 4.9 7.5 5.4 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CCDC53 PF10152.9 KND93577.1 - 4.9 7.6 8.2 0.42 11.0 2.3 2.1 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex Spc7 PF08317.11 KND93577.1 - 8.2 5.2 13.8 0.68 8.8 1.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 KND93577.1 - 9.5 5.7 12.9 5e+02 0.0 12.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 KND93577.1 - 9.9 6.0 12.1 0.17 11.7 3.2 2.3 2 1 0 2 2 2 0 Septum formation initiator TruB_N PF01509.18 KND93578.1 - 1.4e-43 148.8 0.0 3.3e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KND93578.1 - 3.3e-06 27.2 0.0 6.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UCH_1 PF13423.6 KND93579.1 - 8.4e-40 137.3 0.0 7.8e-39 134.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fes1 PF08609.10 KND93580.1 - 2.1e-30 105.5 1.5 2.1e-30 105.5 1.5 2.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KND93580.1 - 1e-07 31.8 0.0 0.024 14.7 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KND93580.1 - 2.2e-07 31.2 0.4 6.1e-05 23.4 0.1 2.6 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KND93580.1 - 6.9e-06 26.4 0.1 1.8e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 KND93580.1 - 0.00017 21.5 0.2 0.14 12.5 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat Atx10homo_assoc PF09759.9 KND93580.1 - 0.018 15.1 0.2 0.14 12.2 0.1 2.0 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain 6PF2K PF01591.18 KND93581.1 - 6e-58 195.8 0.0 8.5e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KND93581.1 - 1.1e-22 80.8 0.7 1.7e-21 76.8 0.7 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KND93581.1 - 0.013 15.6 0.1 0.41 10.8 0.1 2.5 1 1 0 1 1 1 0 AAA domain ZnuA PF01297.17 KND93581.1 - 0.017 14.6 0.0 0.039 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic IstB_IS21 PF01695.17 KND93581.1 - 0.032 13.9 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Hydin_ADK PF17213.3 KND93581.1 - 0.16 12.2 0.7 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Porin_3 PF01459.22 KND93582.1 - 3.5e-85 285.7 0.0 4.1e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.25 KND93583.1 - 7.5e-65 218.9 0.0 8.8e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93583.1 - 2e-25 89.5 0.0 2.7e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93583.1 - 1.6e-06 27.7 0.0 7.9e-06 25.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KND93583.1 - 0.0025 17.8 0.2 0.0092 15.9 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 KND93583.1 - 0.006 16.8 0.2 0.0095 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Seadorna_VP7 PF07387.11 KND93583.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KND93583.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KND93583.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DNMT1-RFD PF12047.8 KND93585.1 - 0.00073 19.6 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MFS_1 PF07690.16 KND93588.1 - 3.7e-32 111.6 47.5 4.8e-28 98.1 32.7 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93588.1 - 0.0001 21.3 15.4 0.00018 20.5 6.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter PUCC PF03209.15 KND93588.1 - 0.038 13.0 14.6 0.014 14.5 11.1 1.8 1 1 0 2 2 2 0 PUCC protein Abhydrolase_2 PF02230.16 KND93590.1 - 2.5e-24 86.3 0.0 9.7e-23 81.1 0.0 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KND93590.1 - 4.4e-06 27.5 0.9 2.2e-05 25.2 0.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KND93590.1 - 5.4e-05 22.8 0.0 0.0004 19.9 0.0 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 KND93590.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 KND93590.1 - 0.016 15.1 0.0 2.4 7.9 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KND93590.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KND93590.1 - 0.13 11.5 0.0 34 3.6 0.0 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 GKAP PF03359.13 KND93593.1 - 0.03 13.9 2.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein SEP PF08059.13 KND93594.1 - 1.3e-22 80.1 0.0 2.4e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 KND93594.1 - 7e-10 38.6 0.3 1.1e-09 38.0 0.3 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KND93594.1 - 1.6e-09 37.8 0.0 3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Sporozoite_P67 PF05642.11 KND93594.1 - 0.019 13.1 2.1 0.028 12.5 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 KND93595.1 - 1.7e-08 34.1 0.0 3e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93595.1 - 0.00045 19.6 0.0 0.00066 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KND93595.1 - 0.0062 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KND93595.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CHAD PF05235.14 KND93595.1 - 0.047 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 CHAD domain Kdo PF06293.14 KND93595.1 - 0.085 12.2 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 KND93596.1 - 0.00056 20.2 0.0 0.29 11.5 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 KND93596.1 - 0.0054 15.4 17.7 0.0071 15.0 17.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nup160 PF11715.8 KND93596.1 - 0.061 12.0 0.0 0.095 11.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CDC45 PF02724.14 KND93596.1 - 0.14 10.5 12.1 0.19 10.0 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 KND93596.1 - 0.44 10.2 3.8 0.64 9.7 3.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 KND93596.1 - 0.46 9.9 13.8 0.64 9.4 13.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KND93596.1 - 0.57 8.3 12.6 0.75 7.9 12.6 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KND93596.1 - 0.93 7.9 13.6 1.3 7.4 13.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Antimicrobial22 PF16047.5 KND93596.1 - 1.4 8.8 5.2 2.9 7.9 5.2 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Cwf_Cwc_15 PF04889.12 KND93596.1 - 1.5 8.5 17.2 2.2 8.0 17.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 KND93596.1 - 1.9 8.5 17.2 2.9 7.9 17.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 KND93596.1 - 2.2 6.3 21.3 3.1 5.8 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 KND93596.1 - 3.6 8.6 10.1 15 6.7 0.0 4.9 6 0 0 6 6 5 0 WD domain, G-beta repeat Xan_ur_permease PF00860.20 KND93597.1 - 1.2e-61 208.6 28.3 4e-59 200.3 28.3 2.1 1 1 0 1 1 1 1 Permease family GDPD PF03009.17 KND93598.1 - 5.4e-12 46.0 0.0 7.1e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2782 PF11191.8 KND93598.1 - 0.1 12.8 0.0 2 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) Glyco_hydro_18 PF00704.28 KND93599.1 - 9.8e-63 212.7 0.0 1.1e-62 212.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 KND93599.1 - 0.049 14.0 0.1 0.24 11.8 0.0 2.0 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family GHL15 PF14885.6 KND93599.1 - 0.078 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Oxidored_molyb PF00174.19 KND93600.1 - 1.8e-56 190.5 0.0 2.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KND93600.1 - 3.3e-22 79.0 0.0 1.5e-11 44.5 0.0 3.2 3 0 0 3 3 3 2 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KND93600.1 - 5.8e-11 42.4 0.1 1.1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain mRNA_triPase PF02940.15 KND93602.1 - 1.9e-53 181.5 0.0 3.2e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Macoilin PF09726.9 KND93602.1 - 0.15 10.6 3.2 0.33 9.5 3.2 1.5 1 0 0 1 1 1 0 Macoilin family RPN2_C PF18004.1 KND93603.1 - 1.5e-52 177.8 4.2 3.7e-51 173.2 4.3 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KND93603.1 - 9.7e-41 136.2 15.3 2.1e-09 37.4 0.0 8.4 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KND93603.1 - 1.7e-22 79.6 0.1 4.2e-14 52.7 0.0 5.5 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 KND93603.1 - 2.3e-06 27.3 0.6 1.8 9.0 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KND93603.1 - 1e-05 25.9 0.6 0.011 16.2 0.0 5.3 4 1 1 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 KND93603.1 - 0.003 17.6 0.0 1.5 8.9 0.0 3.2 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 GHMP_kinases_N PF00288.26 KND93603.1 - 0.77 10.0 8.1 6.3 7.1 0.9 3.1 3 0 0 3 3 3 0 GHMP kinases N terminal domain TPR_5 PF12688.7 KND93603.1 - 1 9.6 4.6 1.2e+02 3.0 0.1 4.9 5 1 1 6 6 6 0 Tetratrico peptide repeat Ribosomal_S13 PF00416.22 KND93604.1 - 1.8e-16 60.7 1.6 2.2e-14 53.9 1.6 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 RhoGAP PF00620.27 KND93605.1 - 1.8e-15 57.1 0.0 4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 KND93605.1 - 8.4e-12 45.0 0.0 1.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LTV PF04180.14 KND93606.1 - 3.6e-131 438.4 17.6 4.1e-131 438.3 17.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein ATP-synt_S1 PF05827.12 KND93607.1 - 1.4e-06 28.2 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Trm112p PF03966.16 KND93608.1 - 1.2e-15 57.9 0.1 1.5e-15 57.5 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 KND93608.1 - 0.053 14.0 0.3 0.098 13.2 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Pro_isomerase PF00160.21 KND93609.1 - 2e-49 167.9 0.8 2.4e-49 167.6 0.8 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAC3_GANP PF03399.16 KND93610.1 - 4.2e-83 279.1 0.1 8.2e-83 278.2 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP family EMP24_GP25L PF01105.24 KND93611.1 - 1.8e-46 158.4 2.0 2.1e-46 158.1 2.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Tail_VII PF17091.5 KND93611.1 - 0.12 12.2 1.1 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Inovirus G7P protein SKIP_SNW PF02731.15 KND93612.1 - 1.2e-68 229.8 8.5 1.2e-68 229.8 8.5 2.5 3 0 0 3 3 3 1 SKIP/SNW domain PI3K_1B_p101 PF10486.9 KND93612.1 - 0.26 9.0 12.6 0.44 8.3 12.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sulfatase PF00884.23 KND93613.1 - 8.6e-75 252.0 0.0 1.1e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KND93613.1 - 0.0042 17.3 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KND93613.1 - 0.01 15.5 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase An_peroxidase PF03098.15 KND93613.1 - 0.18 10.4 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase DUF1289 PF06945.13 KND93613.1 - 0.18 11.6 0.2 0.5 10.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) PhoD PF09423.10 KND93614.1 - 2.5e-43 148.4 0.1 5.6e-43 147.3 0.1 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase DUF1772 PF08592.11 KND93616.1 - 1.7e-12 47.9 0.8 1.7e-12 47.9 0.8 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Rrp15p PF07890.12 KND93617.1 - 1.5e-37 129.0 11.0 1.5e-37 129.0 11.0 2.4 2 1 0 2 2 2 1 Rrp15p SDA1 PF05285.12 KND93617.1 - 2.2 7.6 32.1 3.3 7.0 32.1 1.3 1 0 0 1 1 1 0 SDA1 HAGH_C PF16123.5 KND93618.1 - 2e-21 76.2 0.3 3.1e-21 75.7 0.3 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KND93618.1 - 3.7e-16 59.7 0.6 3.2e-09 37.1 0.1 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KND93618.1 - 0.011 15.2 0.4 0.1 12.1 0.4 2.2 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1236 PF06823.12 KND93618.1 - 0.074 12.9 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Las1 PF04031.13 KND93619.1 - 2.2e-58 196.7 3.8 3.3e-58 196.2 3.8 1.3 1 0 0 1 1 1 1 Las1-like PfkB PF00294.24 KND93621.1 - 7.2e-10 38.6 0.0 7.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase NAD_kinase PF01513.21 KND93622.1 - 3.7e-69 233.2 0.0 5.8e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KND93622.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain EBP PF05241.12 KND93623.1 - 4.5e-72 241.2 7.5 5.2e-72 241.0 7.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein Grg1 PF11034.8 KND93624.1 - 1.2e-32 112.0 11.7 1.3e-32 111.8 11.7 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 PAP2 PF01569.21 KND93626.1 - 9.1e-11 41.7 6.9 9.1e-11 41.7 6.9 2.4 2 1 0 2 2 2 1 PAP2 superfamily UbiA PF01040.18 KND93626.1 - 0.00031 20.1 3.1 0.00031 20.1 3.1 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 KND93626.1 - 0.014 15.5 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Divergent PAP2 family DUF2909 PF11137.8 KND93626.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) GTP_EFTU PF00009.27 KND93628.1 - 1.4e-56 191.2 0.1 1.9e-56 190.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KND93628.1 - 1.5e-25 89.7 0.0 3.4e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KND93628.1 - 6.6e-15 55.3 3.2 2.9e-14 53.2 3.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KND93628.1 - 1.8e-05 24.8 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND93628.1 - 0.0014 18.6 0.1 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KND93628.1 - 0.043 13.4 0.1 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KND93628.1 - 0.085 12.6 0.1 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PGA2 PF07543.12 KND93629.1 - 2.5e-38 131.2 3.0 3.2e-38 130.8 3.0 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 TetR_C_13 PF16925.5 KND93630.1 - 0.2 11.6 2.6 2 8.4 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FAM178 PF14816.6 KND93630.1 - 0.55 9.1 2.7 0.77 8.7 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 CLPTM1 PF05602.12 KND93631.1 - 1.1e-148 495.9 0.0 1.4e-148 495.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Longin PF13774.6 KND93632.1 - 6.9e-26 90.1 0.1 1.2e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KND93632.1 - 1.1e-15 57.2 0.0 2.1e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 KND93632.1 - 0.014 15.1 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5435) DUF1664 PF07889.12 KND93632.1 - 0.026 14.5 0.8 0.52 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APH PF01636.23 KND93633.1 - 7.5e-13 48.9 4.3 2.8e-12 47.1 4.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND93633.1 - 9.9e-07 28.6 0.0 1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 KND93633.1 - 0.00066 19.1 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KND93633.1 - 0.002 17.8 0.0 0.026 14.1 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 KND93633.1 - 0.21 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_4 PF13637.6 KND93634.1 - 3.5e-13 49.8 0.0 2.5e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND93634.1 - 6.1e-10 39.6 0.0 9.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND93634.1 - 1.8e-06 28.1 0.0 0.02 15.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93634.1 - 8.4e-06 25.8 0.0 0.027 15.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 KND93634.1 - 1.5e-05 25.2 0.1 0.0025 18.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat LAGLIDADG_WhiA PF14527.6 KND93634.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain IGPD PF00475.18 KND93636.1 - 7.5e-54 182.0 0.3 3.5e-53 179.8 0.3 1.9 1 1 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase PGM_PMM_II PF02879.16 KND93636.1 - 0.089 13.4 0.0 0.26 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ArgJ PF01960.18 KND93637.1 - 6e-148 492.6 0.0 6.9e-148 492.4 0.0 1.0 1 0 0 1 1 1 1 ArgJ family IF-2B PF01008.17 KND93638.1 - 3.9e-48 164.1 0.5 1.2e-47 162.5 0.5 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family SARS_lipid_bind PF09399.10 KND93638.1 - 0.12 12.5 0.0 0.38 11.0 0.0 1.8 2 0 0 2 2 2 0 SARS lipid binding protein IHABP4_N PF16174.5 KND93638.1 - 3.1 8.4 15.5 5.2 7.6 15.5 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF3684 PF12449.8 KND93640.1 - 0 1448.1 0.0 0 1447.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KND93640.1 - 0.0001 22.1 0.0 0.0003 20.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reprolysin_5 PF13688.6 KND93640.1 - 0.015 15.4 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 WLM PF08325.10 KND93640.1 - 0.046 13.8 0.2 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 WLM domain Radial_spoke_3 PF06098.11 KND93640.1 - 5.7 6.1 7.0 12 5.1 7.0 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 MMtag PF10159.9 KND93641.1 - 6.2e-32 109.7 3.1 1.3e-31 108.7 3.1 1.5 1 0 0 1 1 1 1 Multiple myeloma tumor-associated Hamartin PF04388.12 KND93641.1 - 0.28 9.8 1.2 0.3 9.7 1.2 1.0 1 0 0 1 1 1 0 Hamartin protein Med6 PF04934.14 KND93642.1 - 9e-38 129.1 0.0 1.3e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Glyco_hydro_31 PF01055.26 KND93643.1 - 7e-140 467.1 6.7 9.4e-140 466.7 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KND93643.1 - 2.8e-26 91.6 1.3 3.4e-25 88.1 0.3 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KND93643.1 - 8.7e-07 29.1 0.2 3.7e-06 27.1 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) FLILHELTA PF10306.9 KND93645.1 - 1.5e-30 105.4 0.5 2.7e-30 104.6 0.5 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 KND93645.1 - 0.019 15.5 0.2 0.028 14.9 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.19 KND93646.1 - 1.3e-53 180.6 0.0 1.6e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase LTD PF00932.19 KND93647.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Lamin Tail Domain NHL PF01436.21 KND93649.1 - 0.11 12.6 0.4 0.46 10.6 0.0 2.3 3 0 0 3 3 3 0 NHL repeat Peptidase_M18 PF02127.15 KND93650.1 - 1.2e-128 429.6 0.0 1.4e-128 429.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Tim17 PF02466.19 KND93651.1 - 2.7e-37 127.5 9.6 3.9e-37 127.0 9.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 KND93651.1 - 0.0095 15.9 0.1 0.083 12.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF543) ATP-synt_ab PF00006.25 KND93652.1 - 4.4e-107 356.6 0.0 5.9e-107 356.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KND93652.1 - 6.9e-47 158.3 0.0 1.6e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KND93652.1 - 2.6e-09 37.4 2.4 6.8e-09 36.1 2.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hid1 PF12722.7 KND93653.1 - 6.4e-295 980.5 0.0 7.3e-295 980.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KND93653.1 - 2.6e-93 313.6 0.0 3.1e-93 313.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ACT_7 PF13840.6 KND93654.1 - 7.9e-23 80.0 0.1 1.4e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.19 KND93655.1 - 4.5e-33 113.7 0.1 8.5e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KND93655.1 - 0.0007 19.9 0.0 0.0019 18.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain Syntaxin-6_N PF09177.11 KND93656.1 - 6.7e-25 87.5 0.3 5.3e-24 84.7 0.0 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KND93656.1 - 3.4e-07 30.2 1.5 7.5e-07 29.1 0.6 2.1 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 KND93656.1 - 0.0015 18.3 0.1 0.0036 17.0 0.1 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 Prominin PF05478.11 KND93656.1 - 0.01 13.9 0.2 0.026 12.5 0.1 1.6 2 0 0 2 2 2 0 Prominin Pox_EPC_I2-L1 PF12575.8 KND93656.1 - 0.029 14.6 0.9 2.9 8.2 0.3 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 PCRF PF03462.18 KND93656.1 - 0.041 13.8 1.5 0.76 9.6 0.5 2.1 2 0 0 2 2 2 0 PCRF domain HemX PF04375.14 KND93656.1 - 0.071 12.4 4.1 0.11 11.8 1.3 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1664 PF07889.12 KND93656.1 - 0.25 11.4 4.7 7.8 6.6 1.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 KND93656.1 - 0.26 11.4 8.5 1.6 8.8 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 KND93656.1 - 0.46 10.6 6.1 4.3 7.4 0.0 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 KND93656.1 - 0.57 10.7 3.3 4.9 7.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 CENP-Q PF13094.6 KND93656.1 - 0.57 10.4 5.2 1.1 9.5 0.8 2.3 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.9 KND93656.1 - 1.3 9.0 7.8 5.4 7.0 3.7 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 KND93656.1 - 1.3 9.3 5.8 1.5 9.1 0.2 2.9 2 2 0 2 2 2 0 Spc24 subunit of Ndc80 DUF745 PF05335.13 KND93656.1 - 4 7.1 6.8 1.5 8.5 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TBCA PF02970.16 KND93656.1 - 8.4 6.8 8.4 8.3 6.8 4.1 2.7 2 2 1 3 3 3 0 Tubulin binding cofactor A Methyltransf_32 PF13679.6 KND93657.1 - 6.7e-22 78.2 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RNB PF00773.19 KND93658.1 - 1.5e-76 257.8 0.0 2.5e-76 257.1 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KND93658.1 - 1e-25 89.5 0.0 2.4e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KND93658.1 - 2.1e-25 88.9 0.0 7.3e-25 87.1 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KND93658.1 - 1.1e-05 25.5 0.0 0.017 15.3 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KND93658.1 - 0.075 12.8 0.0 0.075 12.8 0.0 1.8 2 0 0 2 2 2 0 Rrp44-like cold shock domain NPR3 PF03666.13 KND93658.1 - 2.3 6.9 11.5 0.076 11.8 1.8 2.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GLE1 PF07817.13 KND93659.1 - 6.7e-62 209.0 0.0 1e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein TetR_C_24 PF17932.1 KND93659.1 - 0.34 11.2 2.7 0.63 10.3 2.7 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ferritin_2 PF13668.6 KND93660.1 - 2e-38 131.7 0.0 3.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain EST1_DNA_bind PF10373.9 KND93661.1 - 0.0013 18.3 0.0 0.002 17.6 0.0 1.4 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain DUF515 PF04415.12 KND93661.1 - 3.9 5.8 10.3 5.1 5.4 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Gtr1_RagA PF04670.12 KND93662.1 - 6.3e-93 310.4 0.0 8.3e-93 310.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KND93662.1 - 9.1e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KND93662.1 - 2e-07 30.8 0.0 3.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 KND93662.1 - 2.2e-07 30.5 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND93662.1 - 2.4e-07 30.8 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KND93662.1 - 0.00039 19.7 2.5 0.29 10.3 0.4 2.8 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 KND93662.1 - 0.0023 17.7 0.3 0.038 13.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KND93662.1 - 0.0065 17.0 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KND93662.1 - 0.012 15.5 0.2 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KND93662.1 - 0.013 15.0 0.0 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KND93662.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glyco_trans_2_3 PF13632.6 KND93663.1 - 1.8e-49 168.4 1.6 1.8e-49 168.4 1.6 2.0 1 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KND93663.1 - 0.00042 20.2 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KND93663.1 - 0.059 12.8 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 DIOX_N PF14226.6 KND93665.1 - 4.3e-23 82.3 0.0 6.9e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND93665.1 - 6.9e-15 55.4 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 KND93666.1 - 1.5e-71 240.4 0.0 2.1e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KND93666.1 - 1.8e-31 108.3 0.0 3.8e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KND93666.1 - 1.1e-05 25.8 0.0 2.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF4048 PF13257.6 KND93667.1 - 5.8e-06 26.3 0.6 5.8e-06 26.3 0.6 4.4 2 1 2 4 4 4 2 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.21 KND93668.1 - 4.8e-23 81.9 0.0 7.8e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KND93668.1 - 3.2e-16 60.1 0.0 1.3e-15 58.2 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KND93668.1 - 2.2e-07 31.3 0.0 8.1e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 RNA ligase DUF4188 PF13826.6 KND93670.1 - 1.4e-29 102.8 0.5 1.9e-29 102.4 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 KND93670.1 - 0.0007 19.1 0.0 0.00082 18.9 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Glyco_hydro_76 PF03663.14 KND93672.1 - 9e-152 505.8 10.6 1.1e-151 505.6 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND93672.1 - 1.4e-06 27.7 7.7 0.033 13.3 3.9 3.5 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 ECH_2 PF16113.5 KND93673.1 - 1.5e-126 422.4 0.0 1.8e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KND93673.1 - 9.7e-26 90.6 0.1 5.8e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Dak1 PF02733.17 KND93674.1 - 1.3e-100 336.3 8.1 2e-100 335.7 8.1 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KND93674.1 - 1.1e-46 158.9 1.2 9.5e-46 155.9 0.1 2.4 2 0 0 2 2 2 1 DAK2 domain Caps_synth PF05704.12 KND93675.1 - 1.6e-09 37.5 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KND93675.1 - 3.4e-05 24.4 0.0 6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dynamin_N PF00350.23 KND93676.1 - 1.8e-31 109.5 0.0 4.4e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND93676.1 - 5.8e-21 75.0 0.1 4.5e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KND93676.1 - 4.2e-07 30.0 0.1 8.6e-06 25.8 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 KND93676.1 - 4.6e-06 26.7 0.2 1.9e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Roc PF08477.13 KND93676.1 - 0.001 19.3 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 KND93676.1 - 0.027 15.0 0.0 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_27 PF13514.6 KND93676.1 - 0.049 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KND93676.1 - 0.063 12.8 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Ras PF00071.22 KND93676.1 - 0.12 11.9 0.1 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_15 PF13175.6 KND93676.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ank_4 PF13637.6 KND93677.1 - 2.1e-15 56.9 0.1 1.1e-09 38.6 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND93677.1 - 6.8e-13 49.0 0.0 4.8e-12 46.3 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 KND93677.1 - 1.3e-09 38.1 0.1 0.0039 17.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 KND93677.1 - 3.6e-07 29.9 0.0 0.043 14.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KND93677.1 - 1.3e-05 25.4 0.0 5.7e-05 23.3 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NACHT PF05729.12 KND93677.1 - 1.7e-05 24.8 0.2 4.4e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KND93677.1 - 0.00051 20.5 0.3 0.013 15.9 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 KND93677.1 - 0.0021 17.4 0.6 0.012 14.9 0.1 2.1 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 KND93677.1 - 0.0025 18.1 0.0 0.0079 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KND93677.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 KND93679.1 - 2.8e-21 76.0 0.0 1.4e-12 47.5 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND93679.1 - 9.9e-10 38.1 0.0 0.00025 20.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KND93679.1 - 0.0063 16.5 0.0 0.022 14.7 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KND93679.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mid2 PF04478.12 KND93682.1 - 0.045 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PTP_tm PF18861.1 KND93682.1 - 0.16 12.0 1.7 0.32 11.0 1.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 KND93682.1 - 6.2 7.5 5.5 19 5.9 5.5 1.9 1 1 0 1 1 1 0 Small Novel Rich in Cartilage MFS_1 PF07690.16 KND93683.1 - 1.9e-18 66.5 55.3 9.1e-18 64.3 50.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KND93683.1 - 1e-06 27.5 18.2 1e-06 27.5 18.2 1.9 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_72 PF03198.14 KND93684.1 - 9.8e-122 406.1 3.2 1.4e-121 405.6 3.2 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 KND93684.1 - 1.9e-23 82.9 6.7 6e-23 81.3 6.7 1.9 1 0 0 1 1 1 1 X8 domain adh_short PF00106.25 KND93685.1 - 4e-17 62.3 0.0 6.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND93685.1 - 3.6e-13 49.6 0.0 5.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TSCPD PF12637.7 KND93685.1 - 0.0067 16.6 0.2 0.013 15.7 0.2 1.5 1 0 0 1 1 1 1 TSCPD domain KR PF08659.10 KND93685.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 KR domain DUF1776 PF08643.10 KND93685.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PAD PF03068.15 KND93686.1 - 9.1e-127 423.3 0.0 1.2e-126 422.9 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) DUF4908 PF16252.5 KND93686.1 - 0.095 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4908) HET PF06985.11 KND93687.1 - 9e-09 35.8 0.1 3.9e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 KND93688.1 - 0.02 13.9 0.2 0.032 13.3 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ank_2 PF12796.7 KND93690.1 - 3.3e-37 126.9 0.0 4.1e-15 56.1 0.0 4.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND93690.1 - 1.1e-22 77.6 0.0 8.6e-05 22.7 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KND93690.1 - 4.4e-22 78.1 0.0 1e-07 32.3 0.0 4.7 4 1 1 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KND93690.1 - 1.1e-21 76.3 0.0 1.7e-05 25.1 0.0 5.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KND93690.1 - 1.7e-20 72.8 0.0 4e-07 30.2 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 KND93690.1 - 0.00017 21.9 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KND93690.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KND93690.1 - 0.023 15.1 0.1 0.07 13.5 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KND93690.1 - 0.058 13.7 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain VWA_3_C PF18571.1 KND93690.1 - 0.068 13.0 1.4 3.6 7.5 0.0 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain DUF2075 PF09848.9 KND93690.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_S8 PF00082.22 KND93691.1 - 0.00018 20.9 0.0 0.0004 19.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family zinc_ribbon_11 PF11682.8 KND93691.1 - 0.07 13.1 0.8 0.25 11.4 0.7 1.9 1 1 1 2 2 2 0 Probable zinc-ribbon Pmp3 PF01679.17 KND93692.1 - 1.8e-20 72.9 8.9 2.4e-20 72.5 8.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator NapE PF06796.11 KND93692.1 - 0.66 9.5 2.9 1 8.9 2.9 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE UCH PF00443.29 KND93694.1 - 3e-26 92.5 0.0 4.2e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KND93694.1 - 6.1e-13 48.9 0.1 6.1e-13 48.9 0.1 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KND93694.1 - 0.00022 20.9 1.0 0.0093 15.6 1.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 KND93694.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) Utp13 PF08625.11 KND93695.1 - 9.9e-52 174.6 0.9 1.5e-51 174.0 0.9 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 KND93695.1 - 3.4e-46 154.3 29.7 2.9e-05 24.7 0.4 11.9 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND93695.1 - 8.4e-14 51.6 10.8 0.0038 17.5 0.1 8.7 6 3 2 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND93695.1 - 9.5e-08 31.1 3.4 0.21 10.2 0.2 5.5 5 1 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KND93695.1 - 0.042 12.6 3.6 13 4.4 0.0 4.5 5 0 0 5 5 5 0 Nup133 N terminal like Ge1_WD40 PF16529.5 KND93695.1 - 0.1 11.6 2.9 31 3.4 0.0 4.6 5 0 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MCM PF00493.23 KND93697.1 - 2.1e-105 350.8 0.1 2.4e-104 347.3 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KND93697.1 - 4.9e-37 126.6 0.7 9.1e-37 125.7 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND93697.1 - 1.8e-27 95.6 2.1 4.5e-27 94.3 2.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND93697.1 - 3e-16 59.9 0.7 7.3e-16 58.6 0.7 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND93697.1 - 2.4e-06 27.1 0.0 0.00021 20.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND93697.1 - 1.5e-05 25.0 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KND93697.1 - 0.00028 20.8 0.1 0.0014 18.5 0.0 2.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KND93697.1 - 0.05 13.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 KND93697.1 - 0.08 13.4 0.1 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND93697.1 - 0.3 11.4 1.4 3.6 7.9 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.25 KND93698.1 - 1.2e-69 234.6 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93698.1 - 5.9e-35 120.8 0.0 1.4e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93698.1 - 0.001 18.4 0.0 0.0027 17.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KND93698.1 - 0.0019 17.6 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND93698.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KND93698.1 - 0.23 10.3 0.0 0.5 9.3 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Abhydrolase_1 PF00561.20 KND93700.1 - 7.3e-12 45.5 0.0 1.8e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND93700.1 - 7.7e-07 28.6 0.0 2.3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND93700.1 - 0.00053 20.7 0.0 0.001 19.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family IF4E PF01652.18 KND93701.1 - 1.6e-52 177.5 0.1 2.6e-52 176.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ketoacyl-synt PF00109.26 KND93702.1 - 9.9e-73 244.8 3.1 4.7e-72 242.6 1.3 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND93702.1 - 2.2e-32 111.5 0.2 8.6e-21 74.1 0.0 2.9 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 KND93702.1 - 5.7e-23 80.6 0.0 1.6e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain PS-DH PF14765.6 KND93702.1 - 4.2e-20 72.2 0.0 8.5e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 KND93702.1 - 4.9e-17 62.5 0.0 2.1e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 KND93702.1 - 1.2e-15 57.6 1.2 1.2e-15 57.6 1.2 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 KND93702.1 - 3.1e-14 53.2 2.2 1.4e-13 51.1 0.6 2.7 2 1 0 2 2 2 1 Acyl transferase domain Methyltransf_23 PF13489.6 KND93702.1 - 2.8e-11 43.5 0.0 1.3e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_3 PF07859.13 KND93702.1 - 3.1e-11 43.6 0.0 1.7e-07 31.3 0.0 2.8 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 KND93702.1 - 7.5e-11 42.6 0.0 4.3e-10 40.2 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 KND93702.1 - 3.4e-10 40.1 8.7 5.7e-10 39.3 0.4 3.7 4 0 0 4 4 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S9 PF00326.21 KND93702.1 - 3.8e-08 33.1 0.1 6.5e-06 25.8 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family KAsynt_C_assoc PF16197.5 KND93702.1 - 4.4e-08 33.6 0.0 1.2e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KND93702.1 - 5.1e-08 33.5 0.0 3.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND93702.1 - 1.5e-06 28.1 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 KND93702.1 - 0.024 13.8 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Hydrolase_4 PF12146.8 KND93702.1 - 0.027 13.8 0.3 0.22 10.7 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Ubie_methyltran PF01209.18 KND93702.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 KND93702.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Thiolase_N PF00108.23 KND93702.1 - 0.16 11.3 0.2 0.31 10.4 0.2 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain SGL PF08450.12 KND93703.1 - 1.9e-11 44.0 0.2 2.6e-10 40.3 0.2 2.3 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region NAD_binding_8 PF13450.6 KND93704.1 - 7.9e-11 42.0 0.2 1.7e-10 41.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KND93704.1 - 1.3e-06 28.1 0.1 2.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND93704.1 - 2.4e-05 23.7 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KND93704.1 - 2.5e-05 23.7 0.0 4.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KND93704.1 - 0.00021 20.1 0.1 0.00036 19.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KND93704.1 - 0.00024 20.8 0.5 0.0067 16.0 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KND93704.1 - 0.0019 18.7 0.0 0.0054 17.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND93704.1 - 0.011 14.8 0.3 0.019 14.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KND93704.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Transp_inhibit PF18791.1 KND93705.1 - 0.011 15.2 0.4 0.028 13.9 0.1 1.8 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain GTP_EFTU PF00009.27 KND93705.1 - 0.06 12.9 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Zn_clus PF00172.18 KND93706.1 - 4e-09 36.4 8.7 4e-09 36.4 8.7 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KND93707.1 - 1e-29 103.4 0.0 8.3e-22 77.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND93707.1 - 4.7e-20 72.1 0.0 2.5e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND93707.1 - 1.1e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KND93709.1 - 3.6e-24 85.3 0.0 5.1e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KND93709.1 - 4.1e-09 36.3 0.0 6.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KND93709.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain CHAD PF05235.14 KND93709.1 - 0.014 15.4 0.0 34 4.3 0.0 3.2 3 0 0 3 3 3 0 CHAD domain Polysacc_synt_2 PF02719.15 KND93709.1 - 0.021 14.0 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.12 KND93709.1 - 0.023 15.4 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KND93709.1 - 0.064 13.9 0.0 3.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 KND93709.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ketoacyl-synt PF00109.26 KND93710.1 - 1.8e-71 240.7 2.5 4.2e-71 239.5 2.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND93710.1 - 1.9e-30 105.3 0.0 4.4e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KND93710.1 - 5.2e-28 98.5 0.0 2e-27 96.5 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain HTH_51 PF18558.1 KND93710.1 - 1.1e-25 89.3 0.0 3.6e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain SAT PF16073.5 KND93710.1 - 6e-18 65.5 8.8 1.8e-14 54.1 0.3 4.6 3 3 1 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KND93710.1 - 4.4e-12 45.8 0.1 8.9e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 KND93710.1 - 1.1e-11 44.8 1.2 2.5e-11 43.8 0.2 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 KND93710.1 - 3.3e-07 29.9 0.1 6.3e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KND93710.1 - 2.9e-05 24.5 0.0 0.00065 20.1 0.0 2.5 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KND93710.1 - 0.0012 19.5 0.0 0.004 17.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND93710.1 - 0.034 14.9 0.0 0.23 12.2 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.19 KND93711.1 - 2.4e-17 63.2 6.1 4.6e-16 59.0 5.5 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KND93711.1 - 0.00011 22.2 0.2 0.00044 20.3 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding SE PF08491.10 KND93711.1 - 0.12 11.3 0.0 4 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KND93711.1 - 0.23 11.0 9.8 0.61 9.6 7.1 2.8 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND93711.1 - 0.33 11.2 3.1 0.6 10.4 0.7 2.5 2 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lysine_decarbox PF03641.14 KND93712.1 - 6.9e-31 107.1 0.1 9.7e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KND93712.1 - 6.6e-07 29.0 1.8 2e-06 27.5 1.8 1.9 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 KND93712.1 - 0.00046 19.5 0.1 0.00076 18.8 0.1 1.4 1 1 0 1 1 1 1 SLOG in TRPM, prokaryote DAGK_cat PF00781.24 KND93712.1 - 0.023 14.3 0.8 6.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain HET PF06985.11 KND93714.1 - 1.2e-31 110.1 0.0 3.1e-31 108.7 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pox_H7 PF04787.12 KND93714.1 - 0.19 12.2 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 Late protein H7 Toxin_23 PF08093.11 KND93714.1 - 0.23 11.6 0.5 0.45 10.7 0.5 1.5 1 0 0 1 1 1 0 Magi 5 toxic peptide family ASXH PF13919.6 KND93715.1 - 1.2e-36 125.8 2.7 1.4e-36 125.6 2.7 1.0 1 0 0 1 1 1 1 Asx homology domain Elong_Iki1 PF10483.9 KND93716.1 - 2.3e-82 276.8 0.0 3.1e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 FTHFS PF01268.19 KND93716.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase COesterase PF00135.28 KND93717.1 - 2.5e-17 63.0 0.0 4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Fic PF02661.18 KND93717.1 - 7.7e-15 55.6 0.0 1.5e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Abhydrolase_1 PF00561.20 KND93718.1 - 5.6e-21 75.3 0.1 5e-20 72.2 0.1 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND93718.1 - 9.1e-16 59.1 0.8 1.1e-15 58.9 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND93718.1 - 1.1e-08 34.6 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 KND93718.1 - 0.023 15.1 0.4 0.039 14.3 0.4 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Fungal_trans PF04082.18 KND93720.1 - 5.1e-22 78.2 0.4 8e-22 77.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3948 PF13134.6 KND93720.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) adh_short_C2 PF13561.6 KND93722.1 - 4.9e-43 147.4 2.4 1.4e-32 113.2 0.3 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND93722.1 - 3.6e-28 98.4 0.3 3.3e-19 69.1 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase AMP-binding PF00501.28 KND93723.1 - 1.6e-84 284.0 0.0 2.8e-83 279.9 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND93723.1 - 3.5e-13 50.3 0.2 8.2e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain INSC_LBD PF16748.5 KND93723.1 - 0.18 11.3 0.5 0.37 10.3 0.5 1.5 1 0 0 1 1 1 0 Inscuteable LGN-binding domain AAA_2 PF07724.14 KND93723.1 - 0.22 11.6 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Spt5-NGN PF03439.13 KND93725.1 - 6.9e-23 80.4 0.0 1.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 KND93725.1 - 8.4e-22 77.5 32.3 1.9e-17 63.6 20.5 4.6 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 KND93725.1 - 1.3e-21 77.4 10.9 1.3e-21 77.4 10.9 3.5 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 KND93725.1 - 8.1e-05 22.4 17.5 0.0034 17.3 1.1 5.2 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KND93725.1 - 0.0016 18.6 0.1 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 KND93725.1 - 2.4 8.4 5.3 4.9 7.4 5.3 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family YajC PF02699.15 KND93725.1 - 7 6.6 9.2 2.1 8.3 1.0 3.5 3 1 1 4 4 4 0 Preprotein translocase subunit UCH PF00443.29 KND93726.1 - 3e-33 115.4 0.0 4.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND93726.1 - 1.8e-06 27.8 0.0 5.5e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 KND93727.1 - 7.7e-35 120.1 0.0 1.8e-34 118.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND93727.1 - 1.3e-23 83.8 0.1 2.4e-23 82.9 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND93727.1 - 3.7e-06 27.0 0.1 5.2e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KND93727.1 - 3.4e-05 23.4 0.0 3.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Rox3 PF08633.10 KND93728.1 - 6.4e-72 242.1 0.0 9.9e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Rox3 mediator complex subunit TDA11 PF17084.5 KND93728.1 - 0.082 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 Fungal_trans PF04082.18 KND93729.1 - 3.2e-23 82.1 0.1 7.7e-23 80.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93729.1 - 1.2e-10 41.3 11.3 2.1e-10 40.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.8 KND93729.1 - 0.022 13.4 0.1 0.054 12.2 0.1 1.5 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor UbiA PF01040.18 KND93730.1 - 6.7e-06 25.6 10.7 0.00076 18.9 10.6 2.8 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KND93731.1 - 6.5e-26 91.1 0.0 8.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KND93733.1 - 1.5e-13 50.1 0.0 7.4e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF998 PF06197.13 KND93734.1 - 0.0078 15.8 1.4 0.02 14.5 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Alpha_GJ PF03229.13 KND93734.1 - 0.011 16.3 6.1 0.011 16.3 6.1 3.5 3 1 0 3 3 3 0 Alphavirus glycoprotein J DUF676 PF05057.14 KND93735.1 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND93735.1 - 1.2e-05 25.1 0.1 9.4e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND93735.1 - 0.0002 22.0 1.0 0.0002 22.0 1.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND93735.1 - 0.035 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KND93735.1 - 0.067 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.20 KND93735.1 - 2.3 8.3 7.6 0.28 11.2 0.2 2.4 2 1 0 2 2 2 0 Thioesterase domain COG2 PF06148.11 KND93736.1 - 4.7e-25 88.2 0.2 8.4e-25 87.4 0.2 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KND93736.1 - 5.4e-05 23.4 0.6 0.00014 22.1 0.2 1.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KND93736.1 - 0.00041 20.4 0.1 0.0075 16.3 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 KND93736.1 - 0.021 13.7 0.3 0.037 12.9 0.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ArAE_1_C PF11728.8 KND93736.1 - 0.043 13.8 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain DUF4611 PF15387.6 KND93736.1 - 0.067 13.4 2.6 0.16 12.2 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NPV_P10 PF05531.12 KND93736.1 - 0.082 13.4 3.6 0.38 11.2 0.2 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Vps54_N PF10475.9 KND93736.1 - 0.094 12.0 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DLP_helical PF18709.1 KND93736.1 - 0.12 11.6 0.6 0.26 10.5 0.4 1.6 2 0 0 2 2 2 0 Dynamin-like helical domain Sec8_exocyst PF04048.14 KND93736.1 - 0.15 11.9 0.8 1.3 8.9 0.8 2.2 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 KND93736.1 - 0.19 11.8 3.5 0.4 10.8 1.7 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein F-box-like PF12937.7 KND93737.1 - 0.00076 19.3 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND93737.1 - 0.0065 16.3 0.1 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KND93737.1 - 0.039 13.8 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box Imm50 PF15594.6 KND93737.1 - 0.2 11.9 0.0 5.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 50 DUF2065 PF09838.9 KND93737.1 - 2.5 8.2 7.8 3.3 7.8 0.5 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2065) PARP PF00644.20 KND93738.1 - 1.3e-54 184.8 0.0 2.4e-54 183.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KND93738.1 - 2.3e-44 150.8 0.4 3.5e-44 150.2 0.4 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KND93738.1 - 8.5e-21 73.8 0.2 2e-20 72.6 0.2 1.6 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 KND93738.1 - 6.5e-12 45.7 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KND93738.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 KND93738.1 - 0.0001 22.2 0.1 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain Zn_clus PF00172.18 KND93739.1 - 1.8e-18 66.4 23.0 1.5e-09 37.8 5.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND93739.1 - 8.8e-17 61.0 0.3 1.3e-16 60.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_tranf_2_2 PF10111.9 KND93740.1 - 0.2 11.1 0.0 0.65 9.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DNA_pol_B PF00136.21 KND93741.1 - 6.4e-142 473.5 2.4 9.6e-142 472.9 2.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KND93741.1 - 5.8e-79 265.7 0.0 1.3e-78 264.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KND93741.1 - 2.2e-17 63.3 5.7 5e-17 62.1 5.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 KND93741.1 - 0.00043 20.3 0.2 0.0046 17.0 0.2 2.6 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 KND93741.1 - 0.0043 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 KND93741.1 - 0.01 14.7 0.6 0.87 8.4 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF2614 PF11023.8 KND93741.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rhomboid PF01694.22 KND93742.1 - 2.2e-32 112.2 7.5 2.2e-32 112.2 7.5 2.0 3 0 0 3 3 3 1 Rhomboid family Zn_clus PF00172.18 KND93743.1 - 2.6e-09 37.1 11.9 6e-09 35.9 11.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND93743.1 - 0.0057 15.5 0.8 0.015 14.2 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4685 PF15737.5 KND93743.1 - 0.22 11.9 1.5 4 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4685) zf-rbx1 PF12678.7 KND93744.1 - 5.7e-10 39.3 0.6 5.7e-10 39.3 0.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND93744.1 - 7.1e-07 29.5 8.1 3.8e-06 27.1 8.1 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KND93744.1 - 9.1e-07 28.6 0.5 1.7e-06 27.8 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KND93744.1 - 4.7e-06 26.5 0.6 9.2e-06 25.5 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KND93744.1 - 6.5e-06 26.1 0.7 7.1e-05 22.8 0.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KND93744.1 - 9.8e-06 25.3 5.8 3.4e-05 23.6 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND93744.1 - 0.00018 21.3 1.4 0.00039 20.2 1.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KND93744.1 - 0.0021 17.9 1.1 0.0021 17.9 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND93744.1 - 0.0021 17.6 0.8 0.0059 16.2 0.8 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KND93744.1 - 0.015 15.3 1.3 0.029 14.4 0.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KND93744.1 - 0.017 14.9 0.5 0.017 14.9 0.5 3.2 3 0 0 3 3 3 0 RING-like zinc finger DUF2921 PF11145.8 KND93744.1 - 0.018 12.9 0.1 0.026 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 KND93744.1 - 0.74 9.9 4.6 2.6 8.2 1.4 2.5 2 0 0 2 2 2 0 Zinc-finger HSBP1 PF06825.12 KND93745.1 - 1.8e-10 40.5 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Pkinase PF00069.25 KND93746.1 - 7.2e-62 209.1 0.0 9.7e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93746.1 - 1.3e-26 93.5 0.0 4.7e-18 65.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Fibrillin_U_N PF18193.1 KND93746.1 - 0.065 13.4 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain Kinase-like PF14531.6 KND93746.1 - 0.066 12.5 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KND93746.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KND93746.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KND93746.1 - 0.26 10.2 0.0 1.5 7.7 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain DUF2613 PF11021.8 KND93747.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) RAI1 PF08652.11 KND93748.1 - 3.3e-27 94.5 0.0 9.3e-27 93.0 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease HDA2-3 PF11496.8 KND93749.1 - 0.007 15.6 0.0 0.098 11.8 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Transglut_prok PF09017.10 KND93749.1 - 0.0074 15.7 0.7 0.015 14.7 0.7 1.4 1 0 0 1 1 1 1 Microbial transglutaminase COX5A PF02284.16 KND93750.1 - 1.3e-40 137.6 0.2 1.7e-40 137.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Secapin PF17521.2 KND93750.1 - 0.0096 15.7 0.2 0.02 14.7 0.2 1.4 1 0 0 1 1 1 1 Honey bee peptides DUF3144 PF11342.8 KND93750.1 - 1.5 9.2 5.5 5.6 7.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3144) ELO PF01151.18 KND93751.1 - 6.9e-62 209.2 20.3 8.2e-62 209.0 20.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family F-box-like PF12937.7 KND93752.1 - 1.8e-05 24.5 0.2 3.5e-05 23.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND93752.1 - 0.095 12.6 1.2 0.6 10.1 1.2 2.2 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KND93752.1 - 0.11 13.0 0.5 97 3.6 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Glycogen_syn PF05693.13 KND93754.1 - 0 1165.4 0.0 0 1165.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KND93754.1 - 1.2e-05 25.0 0.0 0.002 17.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KND93754.1 - 1.6e-05 25.3 0.0 0.014 15.8 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KND93754.1 - 2.5e-05 24.3 0.1 5.1e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 KND93754.1 - 7e-05 22.6 0.1 0.00015 21.6 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KND93754.1 - 0.00035 21.1 0.0 0.00078 19.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain WD40 PF00400.32 KND93755.1 - 1.2e-21 76.6 10.9 6.6e-05 23.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 KND93755.1 - 5.6e-12 46.0 0.1 9.9e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KND93755.1 - 0.012 14.3 3.2 0.17 10.5 0.2 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Cohesin_load PF10345.9 KND93756.1 - 2.5e-120 402.8 1.4 3.7e-120 402.2 1.4 1.2 1 0 0 1 1 1 1 Cohesin loading factor Transglut_core PF01841.19 KND93756.1 - 1.1e-11 45.2 0.3 3.2e-11 43.7 0.3 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KND93756.1 - 8e-08 31.9 0.2 1.7e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND93756.1 - 0.0003 20.3 1.0 0.00067 19.2 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KND93756.1 - 0.042 13.7 0.2 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 Variant SH3 domain Pkinase PF00069.25 KND93757.1 - 4.5e-69 232.7 0.0 6.5e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93757.1 - 1.2e-48 165.7 0.0 1.8e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93757.1 - 4.1e-06 26.3 0.0 2.1e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KND93757.1 - 6.2e-06 25.3 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KND93757.1 - 0.033 13.5 0.1 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MS_channel PF00924.18 KND93758.1 - 1.1e-20 74.1 0.5 1.8e-20 73.4 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KND93758.1 - 0.00066 19.0 1.7 0.0017 17.8 1.7 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KND93758.1 - 0.0014 19.1 0.1 0.0033 17.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KND93758.1 - 0.0029 17.4 0.3 0.0076 16.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KND93758.1 - 0.027 13.9 0.6 0.069 12.7 0.6 1.7 1 0 0 1 1 1 0 EF hand Ribosomal_L1 PF00687.21 KND93760.1 - 5.4e-26 91.6 0.6 2e-25 89.7 0.0 1.8 1 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Hap4_Hap_bind PF10297.9 KND93761.1 - 6.7e-09 35.6 6.9 1.5e-08 34.5 6.9 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KND93761.1 - 9.8e-05 22.4 5.0 0.0002 21.4 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor RBM39linker PF15519.6 KND93761.1 - 0.36 12.0 3.8 0.64 11.1 0.0 3.1 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF4200 PF13863.6 KND93761.1 - 0.79 10.1 10.7 1.4 9.4 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) OEP PF02321.18 KND93761.1 - 4.1 7.2 5.8 6.9 6.4 5.8 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein DUF3052 PF11253.8 KND93762.1 - 0.094 12.6 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) Herpes_U44 PF04533.13 KND93763.1 - 0.00082 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Herpes virus U44 protein DUF3425 PF11905.8 KND93764.1 - 2.1e-27 95.6 0.0 3.2e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KND93764.1 - 0.0044 17.1 1.6 0.0083 16.2 1.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor Spem1 PF15670.5 KND93764.1 - 0.032 13.8 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Fungal_trans_2 PF11951.8 KND93765.1 - 7e-11 41.6 0.4 5.1e-10 38.7 0.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93765.1 - 2e-06 27.8 5.8 4e-06 26.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 KND93766.1 - 2.4e-14 52.7 0.0 4.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 KND93766.1 - 3.7e-07 31.0 3.6 3.7e-07 31.0 3.6 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND93766.1 - 1.4e-06 27.7 0.0 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KND93766.1 - 3.1e-06 26.3 0.0 7e-06 25.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KND93766.1 - 6.5e-06 26.0 0.0 2.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 KND93766.1 - 4.7e-05 23.2 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Lipase_3 PF01764.25 KND93766.1 - 0.0079 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF4350 PF14258.6 KND93766.1 - 0.024 15.0 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Chlorophyllase PF07224.11 KND93766.1 - 0.073 12.1 0.0 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase PGAP1 PF07819.13 KND93766.1 - 0.085 12.6 0.2 0.13 12.0 0.2 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF982 PF06169.12 KND93768.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) GLEYA PF10528.9 KND93769.1 - 1.8e-17 63.5 0.6 3.7e-17 62.5 0.6 1.5 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 KND93769.1 - 2e-09 37.4 0.1 4.3e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 PA14 domain p450 PF00067.22 KND93770.1 - 6.4e-47 160.3 0.0 1e-46 159.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KND93770.1 - 0.078 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 Fungal_trans_2 PF11951.8 KND93771.1 - 4.1e-10 39.0 0.2 1.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93771.1 - 9.6e-06 25.6 12.2 1.6e-05 24.9 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HCBP_related PF06594.11 KND93773.1 - 0.031 14.2 0.1 0.082 12.9 0.0 1.7 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain NPP1 PF05630.11 KND93775.1 - 5.5e-50 170.2 1.7 6.4e-50 170.0 1.7 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Ank PF00023.30 KND93776.1 - 4.7e-16 58.4 1.9 0.033 14.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KND93776.1 - 6.2e-14 52.2 0.3 0.0014 19.2 0.0 4.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND93776.1 - 8.1e-14 52.0 0.0 0.00015 22.3 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KND93776.1 - 5.6e-09 36.1 1.5 0.0098 16.2 0.2 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93776.1 - 2.6e-08 33.5 0.2 2.3 9.1 0.0 5.5 5 1 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 KND93777.1 - 3.1e-24 85.3 1.0 2e-11 44.3 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KND93777.1 - 5.3e-16 58.3 1.3 0.00035 20.9 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KND93777.1 - 8.9e-13 48.5 0.2 8.3e-06 26.3 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93777.1 - 2.4e-12 45.9 0.1 0.0061 17.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 KND93777.1 - 1.1e-10 41.6 0.3 2.2e-07 31.0 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Peptidase_M54 PF07998.11 KND93778.1 - 2.2e-10 40.9 2.0 2.6e-10 40.6 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M54 DUF4953 PF16313.5 KND93778.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Peptidase_M10 PF00413.24 KND93778.1 - 0.0098 15.8 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 KND93778.1 - 0.04 13.5 0.1 0.064 12.8 0.1 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 KND93778.1 - 0.047 13.8 0.1 0.074 13.2 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KND93778.1 - 0.051 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KND93778.1 - 0.052 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Zincin_1 PF06262.11 KND93778.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M43 PF05572.13 KND93778.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.9 KND93778.1 - 0.12 11.3 0.1 0.26 10.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase M66 HTH_32 PF13565.6 KND93778.1 - 0.16 12.6 1.3 2 9.1 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain Metallopep PF12044.8 KND93778.1 - 0.22 10.1 0.1 0.35 9.4 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family PUL PF08324.11 KND93779.1 - 9.1e-60 202.2 0.1 1.2e-59 201.9 0.1 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KND93779.1 - 1.1e-34 119.5 0.0 1.7e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KND93779.1 - 2.7e-12 46.6 0.0 5.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KND93779.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KND93779.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KND93779.1 - 0.027 14.9 0.1 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain EAV_GS PF01309.18 KND93779.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein Aa_trans PF01490.18 KND93780.1 - 1.4e-84 284.2 30.6 1.8e-84 283.8 30.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Suc_Fer-like PF06999.12 KND93780.1 - 4.2e-33 114.9 0.0 7.5e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 KND93780.1 - 9.5e-08 32.3 0.0 2.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND93780.1 - 0.0009 19.9 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KND93780.1 - 0.22 11.6 0.1 0.52 10.4 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain AA_permease PF00324.21 KND93781.1 - 1.8e-57 195.0 31.5 2.3e-57 194.6 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KND93781.1 - 2e-22 79.9 2.9 1.2e-08 34.5 0.0 3.1 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 KND93781.1 - 1.7e-21 76.6 37.4 2.5e-21 76.0 37.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2406 PF10295.9 KND93781.1 - 0.14 12.9 0.3 0.35 11.6 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein (DUF2406) Hamartin PF04388.12 KND93782.1 - 0.11 11.1 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Hamartin protein DZR PF12773.7 KND93782.1 - 0.17 11.9 1.6 0.28 11.3 0.2 2.0 2 0 0 2 2 2 0 Double zinc ribbon cobW PF02492.19 KND93783.1 - 1.5e-40 138.6 0.0 4.9e-40 137.0 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KND93783.1 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KND93783.1 - 0.0085 16.4 0.1 0.12 12.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KND93783.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KND93783.1 - 0.019 14.7 0.3 0.37 10.6 0.1 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF463 PF04317.12 KND93783.1 - 0.05 12.5 0.1 0.093 11.6 0.1 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 RsgA_GTPase PF03193.16 KND93783.1 - 0.058 13.3 0.0 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 KND93783.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 KND93783.1 - 0.071 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 KND93783.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KND93783.1 - 0.08 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GDA1_CD39 PF01150.17 KND93784.1 - 3.2e-83 279.8 0.0 4e-83 279.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GDA1_CD39 PF01150.17 KND93785.1 - 1.2e-13 50.6 0.0 1.2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family UIM PF02809.20 KND93786.1 - 0.46 10.5 5.3 1.2 9.2 5.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Myb_DNA-binding PF00249.31 KND93787.1 - 2.1e-05 24.6 0.1 7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND93787.1 - 0.00063 19.9 0.3 0.0028 17.9 0.2 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.8 KND93787.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.18 KND93788.1 - 1.7e-58 197.9 16.3 1.7e-58 197.9 16.3 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Pkinase PF00069.25 KND93789.1 - 6.7e-18 65.0 0.0 2.6e-08 33.6 0.1 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND93789.1 - 1.7e-06 27.5 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 KND93789.1 - 0.0099 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KND93789.1 - 0.018 13.9 0.0 0.02 13.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Aldedh PF00171.22 KND93790.1 - 1.3e-182 607.4 0.8 1.5e-182 607.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 KND93791.1 - 1.2e-53 182.5 39.5 1.2e-53 182.5 39.5 1.6 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 KND93791.1 - 1.1e-19 70.4 31.6 1.8e-19 69.7 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.13 KND93791.1 - 0.0027 17.4 1.4 0.0027 17.4 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1182) DUF3493 PF11998.8 KND93791.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.4 5 0 0 5 5 5 0 Low psii accumulation1 / Rep27 Cu_amine_oxid PF01179.20 KND93792.1 - 2.6e-155 517.4 0.0 3.2e-155 517.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KND93792.1 - 2.4e-14 53.5 0.0 5.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KND93792.1 - 2.2e-12 47.0 0.4 4.7e-12 46.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain NACHT_N PF17100.5 KND93793.1 - 3.9e-61 206.7 0.1 5.6e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KND93793.1 - 4.3e-06 26.7 0.1 9.6e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 NACHT domain VirJ PF06057.11 KND93796.1 - 0.022 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) TPR_2 PF07719.17 KND93797.1 - 3.5e-31 104.8 26.9 0.00015 21.6 0.0 10.7 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 KND93797.1 - 3.7e-28 96.1 14.5 0.00012 21.7 0.6 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KND93797.1 - 2.1e-24 85.6 17.4 2.9e-23 81.9 0.4 5.3 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KND93797.1 - 4.6e-24 84.7 20.3 0.00081 19.9 0.3 7.9 5 2 4 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KND93797.1 - 8.7e-24 81.7 9.2 0.0053 16.9 0.2 9.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 KND93797.1 - 1.8e-19 69.8 22.8 1.5e-07 31.6 0.1 9.0 7 3 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 KND93797.1 - 6.8e-16 57.6 28.2 0.0011 19.7 0.1 10.0 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 KND93797.1 - 2.3e-13 50.5 29.6 0.00029 21.4 0.6 9.2 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 KND93797.1 - 3.6e-12 45.7 13.3 0.0015 18.3 0.2 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KND93797.1 - 2.6e-10 40.3 6.2 1e-05 25.6 0.5 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND93797.1 - 9e-10 38.1 11.7 0.0021 17.7 0.0 7.5 7 1 1 8 8 8 4 TPR repeat TPR_7 PF13176.6 KND93797.1 - 1.1e-09 37.6 20.2 0.8 9.9 0.1 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 KND93797.1 - 2.2e-08 34.2 12.0 0.76 10.5 0.1 8.9 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_4 PF07721.14 KND93797.1 - 0.01 16.4 16.3 5.2 8.0 0.0 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat MIT PF04212.18 KND93797.1 - 0.02 14.9 2.0 26 5.0 0.0 4.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 KND93797.1 - 0.053 13.6 0.4 49 4.1 0.0 4.1 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region RPN7 PF10602.9 KND93797.1 - 0.058 13.1 2.1 11 5.6 0.0 4.1 3 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 KND93797.1 - 0.38 10.4 12.1 3 7.5 0.1 4.9 6 1 0 6 6 5 0 Tetratricopeptide repeat-like domain TPR_5 PF12688.7 KND93797.1 - 0.45 10.8 3.6 0.36 11.1 0.2 2.7 3 1 0 3 3 1 0 Tetratrico peptide repeat TPR_20 PF14561.6 KND93797.1 - 5 7.5 8.8 13 6.2 0.2 4.7 3 2 2 5 5 5 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 KND93798.1 - 8.1e-55 185.9 0.0 1.1e-54 185.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND93798.1 - 4e-46 156.9 0.0 5.1e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND93798.1 - 1.7e-07 31.3 0.0 3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND93798.1 - 0.0039 16.4 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KND93798.1 - 0.052 13.0 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HEPN_LA2681 PF18733.1 KND93798.1 - 0.053 12.8 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 LA2681-like HEPN ThiF PF00899.21 KND93798.1 - 0.2 11.0 0.3 0.39 10.0 0.2 1.5 1 1 0 1 1 1 0 ThiF family HA2 PF04408.23 KND93799.1 - 1.2e-25 89.9 0.0 5.4e-25 87.8 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KND93799.1 - 3.6e-11 43.4 0.0 1.6e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KND93799.1 - 1.3e-10 41.5 0.0 2.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KND93799.1 - 3.3e-08 33.5 0.0 1.5e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KND93799.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND93799.1 - 0.00054 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KND93799.1 - 0.00082 19.7 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KND93799.1 - 0.0081 15.6 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 KND93799.1 - 0.023 13.7 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KND93799.1 - 0.054 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 KND93799.1 - 0.055 14.0 0.0 0.055 14.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain DHDPS PF00701.22 KND93800.1 - 2.9e-34 118.1 0.0 3.9e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family EcKinase PF02958.20 KND93801.1 - 1.7e-10 40.7 0.0 0.00018 20.9 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 KND93801.1 - 4.4e-08 33.4 1.4 1.3e-07 31.8 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND93801.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_9 PF14658.6 KND93802.1 - 0.0044 17.3 0.0 0.41 11.0 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KND93802.1 - 0.092 13.2 0.0 3.6 8.1 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 KND93802.1 - 0.14 12.1 0.0 20 5.4 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain POT1PC PF16686.5 KND93803.1 - 7.3e-48 162.4 0.0 2.5e-47 160.6 0.0 2.0 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KND93803.1 - 5.5e-16 58.7 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 KND93803.1 - 0.01 15.7 0.3 0.045 13.7 0.0 2.2 2 0 0 2 2 2 0 Replication protein A OB domain STAG PF08514.11 KND93804.1 - 7.3e-33 112.9 1.3 2.6e-32 111.1 0.1 2.7 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 KND93804.1 - 6.1e-06 26.5 0.0 0.0017 18.7 0.0 3.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KND93804.1 - 0.0035 17.5 0.1 25 5.5 0.0 4.9 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KND93804.1 - 0.0036 17.4 0.0 9 6.3 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF724 PF05266.14 KND93804.1 - 0.21 11.4 3.1 0.23 11.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) zf-C2HE PF16278.5 KND93805.1 - 5.7e-18 65.1 0.0 9.3e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KND93805.1 - 9.4e-15 55.1 1.0 9.6e-08 32.5 0.3 2.2 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KND93805.1 - 7.2e-14 52.3 0.1 1.8e-13 51.0 0.1 1.6 1 1 0 1 1 1 1 HIT domain Arm PF00514.23 KND93806.1 - 3e-93 303.4 15.1 1.2e-12 47.4 0.2 8.7 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KND93806.1 - 3.6e-27 94.6 1.3 1.3e-26 92.9 1.3 2.0 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KND93806.1 - 1.2e-22 79.2 2.2 3.2e-22 77.8 2.2 1.8 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KND93806.1 - 6.8e-20 71.2 7.0 3.4e-08 33.8 0.1 6.2 5 1 1 6 6 6 3 HEAT-like repeat HA2 PF04408.23 KND93806.1 - 2e-17 63.4 0.3 1.3e-15 57.5 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) HEAT_2 PF13646.6 KND93806.1 - 2.3e-17 63.1 0.0 1.2e-07 32.1 0.0 5.3 2 2 1 4 4 4 3 HEAT repeats Helicase_C PF00271.31 KND93806.1 - 1.4e-16 60.8 0.0 5.2e-16 59.0 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KND93806.1 - 4e-16 57.7 0.2 7.4e-05 22.7 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat OB_NTP_bind PF07717.16 KND93806.1 - 6.7e-15 55.2 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KND93806.1 - 5.1e-09 36.1 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 KND93806.1 - 1.3e-06 28.7 1.5 2.6e-06 27.7 1.5 1.5 1 0 0 1 1 1 1 RWD domain Arm_2 PF04826.13 KND93806.1 - 3.1e-05 23.6 0.0 0.13 11.7 0.0 3.6 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 KND93806.1 - 0.00032 19.4 0.0 0.0048 15.5 0.0 2.3 1 1 2 3 3 3 1 Adaptin N terminal region AAA_25 PF13481.6 KND93806.1 - 0.00039 20.1 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KND93806.1 - 0.017 14.5 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC DND1_DSRM PF14709.7 KND93806.1 - 0.025 14.8 0.4 0.059 13.6 0.0 1.8 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 HEAT_PBS PF03130.16 KND93806.1 - 0.025 15.2 0.1 7.1 7.6 0.0 4.2 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat dsRBD2 PF17842.1 KND93806.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 V-ATPase_H_C PF11698.8 KND93806.1 - 0.026 14.6 0.1 10 6.3 0.0 4.1 4 2 1 5 5 4 0 V-ATPase subunit H Cnd1 PF12717.7 KND93806.1 - 0.032 14.3 0.0 14 5.7 0.0 2.9 3 0 0 3 3 2 0 non-SMC mitotic condensation complex subunit 1 AAA_29 PF13555.6 KND93806.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KND93806.1 - 0.056 13.7 2.6 0.59 10.4 2.6 2.4 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 KND93806.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RICTOR_V PF14668.6 KND93806.1 - 0.22 11.8 2.4 15 5.9 0.0 3.9 3 2 2 5 5 4 0 Rapamycin-insensitive companion of mTOR, domain 5 AAA_23 PF13476.6 KND93806.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.3 3 0 0 3 3 1 0 AAA domain Kinesin PF00225.23 KND93807.1 - 9.8e-115 383.0 0.0 1.6e-114 382.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KND93807.1 - 2.8e-26 92.3 0.4 6.6e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 KND93807.1 - 0.0033 16.4 10.1 0.004 16.1 8.9 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein YabA PF06156.13 KND93807.1 - 0.0074 16.9 4.5 4.6 7.9 2.1 3.2 2 1 0 2 2 2 2 Initiation control protein YabA Noggin PF05806.12 KND93807.1 - 0.14 12.1 0.9 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Noggin Tau95 PF09734.9 KND93807.1 - 0.15 12.9 1.5 0.32 11.8 1.5 1.5 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain HlyD_2 PF12700.7 KND93807.1 - 0.26 10.0 3.9 0.38 9.4 3.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF87 PF01935.17 KND93807.1 - 0.76 9.8 0.0 0.76 9.8 0.0 3.2 3 1 0 3 3 3 0 Helicase HerA, central domain DUF2018 PF09442.10 KND93807.1 - 0.92 10.5 5.9 5 8.2 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF5094 PF17015.5 KND93807.1 - 1 9.5 5.6 2.7 8.1 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Cwf_Cwc_15 PF04889.12 KND93808.1 - 0.058 13.1 3.2 0.084 12.6 3.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TAF1D PF15333.6 KND93808.1 - 0.84 9.3 3.6 12 5.5 0.5 2.5 1 1 1 2 2 2 0 TATA box-binding protein-associated factor 1D IF4E PF01652.18 KND93809.1 - 8.4e-35 119.9 0.0 1.1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.25 KND93811.1 - 3.6e-44 151.1 0.0 3.7e-43 147.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93811.1 - 2e-31 109.2 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93811.1 - 0.00039 19.8 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND93811.1 - 0.0005 19.5 0.0 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_trans_1_4 PF13692.6 KND93811.1 - 0.14 12.6 0.0 0.69 10.3 0.0 2.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 NUP PF06516.11 KND93812.1 - 1.4e-130 435.1 0.0 1.6e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MFS_1 PF07690.16 KND93813.1 - 5.4e-44 150.6 27.7 5.4e-44 150.6 27.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND93813.1 - 2.6e-08 33.2 6.7 2.6e-08 33.2 6.7 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 KND93813.1 - 1.7e-05 24.3 5.2 1.7e-05 24.3 5.2 1.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 KND93813.1 - 0.00015 20.1 1.6 0.0012 17.2 1.1 2.1 1 1 1 2 2 2 1 BT1 family TRI12 PF06609.13 KND93813.1 - 0.00047 18.7 0.4 0.00047 18.7 0.4 2.5 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) DUF4191 PF13829.6 KND93813.1 - 0.69 9.2 4.2 3.8 6.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Zn_clus PF00172.18 KND93814.1 - 7.8e-06 25.9 4.0 1.4e-05 25.1 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1748 PF08520.10 KND93815.1 - 7e-28 96.3 0.0 1.1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KND93816.1 - 1.3e-170 566.9 4.7 1.6e-170 566.6 4.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KND93816.1 - 1.1e-36 125.6 0.0 2.8e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KND93816.1 - 0.00015 21.0 1.1 0.00056 19.1 0.4 2.1 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KND93816.1 - 0.032 13.2 0.0 0.58 9.1 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain WD40 PF00400.32 KND93817.1 - 1.4e-13 51.0 6.2 1.2e-05 26.0 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat FliD_N PF02465.18 KND93818.1 - 0.0082 16.8 0.7 0.13 13.0 0.1 2.6 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 N-terminus GTP-bdg_M PF16360.5 KND93818.1 - 2.1 9.0 13.6 0.086 13.4 2.9 3.6 3 1 1 4 4 4 0 GTP-binding GTPase Middle Region Cation_ATPase_C PF00689.21 KND93819.1 - 7.6e-43 146.3 5.8 7.6e-43 146.3 5.8 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KND93819.1 - 1.4e-33 116.0 1.6 4.1e-33 114.4 1.6 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KND93819.1 - 1.2e-21 76.6 0.0 2.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND93819.1 - 3e-16 60.3 0.2 4.5e-15 56.5 0.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND93819.1 - 1.7e-06 28.0 0.6 1.2e-05 25.2 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND93819.1 - 4.1e-06 26.4 0.2 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Dak1_2 PF13684.6 KND93819.1 - 0.01 14.9 1.7 0.017 14.2 1.7 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Hol_Tox PF16935.5 KND93819.1 - 0.03 14.4 0.0 1.6 8.8 0.0 2.8 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) ABC_membrane PF00664.23 KND93820.1 - 1.9e-85 286.8 22.3 4.6e-46 157.7 0.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND93820.1 - 1.6e-58 197.1 0.0 4e-28 98.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND93820.1 - 1.7e-14 53.8 1.3 0.00016 21.2 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KND93820.1 - 3.7e-11 43.4 0.1 0.0053 16.6 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KND93820.1 - 1.9e-07 30.7 1.0 0.006 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KND93820.1 - 1.8e-06 27.9 0.3 0.078 12.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KND93820.1 - 3.1e-06 27.7 2.1 0.035 14.5 0.9 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND93820.1 - 5.9e-06 26.6 1.7 0.23 11.7 0.3 3.8 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KND93820.1 - 0.00014 20.8 0.2 0.0032 16.3 0.0 2.6 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 KND93820.1 - 0.00018 21.2 0.3 1.2 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 KND93820.1 - 0.00071 19.7 0.9 0.65 10.1 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain SbcCD_C PF13558.6 KND93820.1 - 0.001 19.2 0.8 0.25 11.6 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 KND93820.1 - 0.0045 16.9 0.0 3.4 7.6 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_5 PF07728.14 KND93820.1 - 0.008 16.2 0.5 8.7 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KND93820.1 - 0.015 15.0 0.2 7.5 6.2 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 KND93820.1 - 0.017 14.9 0.0 5.2 6.7 0.0 3.2 4 0 0 4 4 4 0 AAA domain DUF3987 PF13148.6 KND93820.1 - 0.017 14.2 0.1 0.44 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 KND93820.1 - 0.021 14.9 2.8 0.47 10.5 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KND93820.1 - 0.021 15.0 1.4 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KND93820.1 - 0.025 15.1 0.5 0.97 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KND93820.1 - 0.029 14.9 0.2 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 KND93820.1 - 0.033 13.9 0.0 3.7 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain DEAD PF00270.29 KND93820.1 - 0.056 13.2 0.0 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KND93820.1 - 0.062 13.7 0.2 11 6.4 0.1 2.6 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 KND93820.1 - 8.4 5.7 6.0 24 4.2 0.1 3.2 4 0 0 4 4 4 0 KaiC tRNA-synt_1c PF00749.21 KND93821.1 - 7.5e-104 347.0 0.4 2.4e-102 342.0 0.1 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KND93821.1 - 7.4e-38 130.1 0.0 1.3e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain SurE PF01975.17 KND93822.1 - 1e-28 100.4 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 KND93822.1 - 0.009 16.5 1.6 0.019 15.4 1.6 1.6 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain GIY-YIG PF01541.24 KND93823.1 - 1.7e-12 47.4 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 KND93823.1 - 0.01 16.0 2.5 0.017 15.3 2.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KND93823.1 - 0.025 14.8 3.9 0.04 14.2 3.9 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain T5orf172 PF10544.9 KND93823.1 - 0.053 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain Prok-RING_1 PF14446.6 KND93823.1 - 1.2 9.1 8.9 0.35 10.8 2.2 2.2 1 1 2 3 3 3 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 KND93823.1 - 1.5 9.2 8.4 3.6 8.0 8.4 1.7 1 1 0 1 1 1 0 RING-like domain C1_1 PF00130.22 KND93823.1 - 2.7 7.9 8.3 0.11 12.4 2.5 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3449 PF11931.8 KND93824.1 - 3.8e-26 92.0 2.1 4.2e-24 85.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KND93824.1 - 5.7e-25 87.6 0.7 5.7e-25 87.6 0.7 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KND93824.1 - 9.1e-11 41.4 0.1 1.9e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 KND93824.1 - 9.1e-07 29.0 0.2 1.8e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KND93824.1 - 6.3e-06 26.4 0.2 1.3e-05 25.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP9_N PF16958.5 KND93824.1 - 0.011 15.8 16.2 0.016 15.2 0.8 3.4 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KND93824.1 - 0.031 14.6 0.1 0.11 12.8 0.1 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C4H2 PF10146.9 KND93824.1 - 0.048 14.0 0.3 0.048 14.0 0.3 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein DUF4088 PF13317.6 KND93824.1 - 0.095 12.2 0.7 0.19 11.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) GCP_N_terminal PF17681.1 KND93825.1 - 1.2e-39 136.8 0.2 2.5e-39 135.8 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KND93825.1 - 3.4e-28 99.0 0.2 8.7e-28 97.7 0.2 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KND93825.1 - 2.4e-12 46.0 0.1 3.5e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Atypical_Card PF18461.1 KND93825.1 - 0.012 15.9 0.5 0.16 12.2 0.1 2.6 2 0 0 2 2 2 0 Atypical caspase recruitment domain Abhydrolase_2 PF02230.16 KND93826.1 - 2.2e-10 40.7 0.0 2.8e-09 37.1 0.0 2.4 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase LCCL PF03815.19 KND93827.1 - 4.9e-20 71.5 0.3 7.7e-20 70.8 0.3 1.3 1 0 0 1 1 1 1 LCCL domain Peptidase_U4 PF03419.13 KND93827.1 - 0.2 10.9 7.9 0.35 10.1 7.9 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA TGT PF01702.18 KND93828.1 - 7.6e-65 219.3 0.0 9.2e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PQ-loop PF04193.14 KND93829.1 - 3.4e-17 62.0 3.4 1.4e-11 44.0 0.7 2.7 2 1 0 2 2 2 2 PQ loop repeat Fungal_trans PF04082.18 KND93830.1 - 4.5e-14 52.1 0.0 7.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93830.1 - 8.5e-07 29.0 8.7 1.5e-06 28.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KND93831.1 - 2.5e-21 75.6 5.7 6.6e-07 29.9 0.5 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND93831.1 - 8.5e-09 35.6 0.1 0.014 15.6 0.0 5.1 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KND93831.1 - 0.073 13.0 1.4 34 4.6 0.1 4.1 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 KND93831.1 - 0.086 13.4 13.1 1.9 9.1 0.1 5.7 6 0 0 6 6 6 0 PQQ-like domain MTHFR PF02219.17 KND93832.1 - 2.3e-98 329.1 0.0 3.2e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase eIF3_subunit PF08597.10 KND93833.1 - 0.1 12.5 3.6 0.23 11.4 3.6 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Metallophos PF00149.28 KND93834.1 - 1.3e-36 127.0 0.1 2.3e-36 126.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin PF00085.20 KND93835.1 - 1.1e-55 186.0 0.3 2.3e-29 101.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 KND93835.1 - 3.4e-24 85.5 0.4 3.4e-24 85.5 0.4 2.2 3 0 0 3 3 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KND93835.1 - 3.2e-18 66.2 0.0 1.3e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KND93835.1 - 3.5e-15 56.1 0.0 4.4e-07 29.5 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KND93835.1 - 8e-09 35.6 0.0 0.0015 18.7 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KND93835.1 - 6.6e-08 32.8 0.0 0.0016 18.8 0.0 3.5 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KND93835.1 - 2.6e-06 27.3 1.5 0.023 14.6 0.0 2.6 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_6 PF13848.6 KND93835.1 - 0.0001 22.3 0.2 0.77 9.6 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like domain HyaE PF07449.11 KND93835.1 - 0.00029 20.8 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 KND93835.1 - 0.0012 18.6 0.2 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.6 KND93835.1 - 0.0033 17.6 0.3 3.7 7.7 0.0 3.6 2 2 2 4 4 4 1 Thioredoxin Thioredoxin_9 PF14595.6 KND93835.1 - 0.0036 17.1 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 KND93835.1 - 0.0066 16.3 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 KND93835.1 - 0.023 14.9 3.7 6.9 7.0 0.0 3.8 3 2 0 3 3 3 0 Glutaredoxin Ribosomal_S14 PF00253.21 KND93836.1 - 7e-16 57.7 4.0 7.7e-16 57.6 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 KND93836.1 - 0.0049 16.8 1.5 0.0059 16.5 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) CAF-1_p150 PF11600.8 KND93837.1 - 0.0029 17.3 0.5 0.0052 16.5 0.5 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal HEPN_SAV2148 PF18725.1 KND93837.1 - 0.2 11.0 2.8 0.35 10.2 2.8 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN bZIP_2 PF07716.15 KND93837.1 - 0.3 11.2 11.8 0.72 10.0 5.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KND93837.1 - 0.44 10.7 7.0 0.6 10.2 5.7 1.8 1 1 1 2 2 2 0 bZIP transcription factor TAFII28 PF04719.14 KND93838.1 - 1.8e-32 111.2 0.0 3.6e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF3682 PF12446.8 KND93838.1 - 1.5 9.3 18.6 0.28 11.7 12.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) NAM-associated PF14303.6 KND93838.1 - 2.8 8.7 9.8 2.3 8.9 6.6 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Diphthamide_syn PF01866.17 KND93840.1 - 9.7e-89 297.8 0.0 1.2e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PSDC PF12588.8 KND93841.1 - 1.1e-51 174.5 0.1 1.7e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KND93841.1 - 2.8e-32 111.9 0.0 3.9e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MutS_V PF00488.21 KND93842.1 - 1.7e-66 223.9 0.6 2.9e-66 223.1 0.6 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND93842.1 - 1.6e-42 145.9 0.1 3.5e-42 144.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KND93842.1 - 1.2e-33 115.7 0.2 2.5e-33 114.7 0.2 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KND93842.1 - 4.8e-15 56.1 0.0 2e-14 54.1 0.0 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KND93842.1 - 3e-13 49.9 0.2 8e-13 48.5 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 KND93842.1 - 0.0032 18.0 1.0 0.1 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KND93842.1 - 0.082 12.5 0.3 0.31 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KND93842.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KND93842.1 - 0.26 11.1 3.1 0.13 12.0 0.2 2.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FAD_binding_3 PF01494.19 KND93843.1 - 6e-11 42.2 0.0 1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Sirohm_synth_C PF14823.6 KND93843.1 - 0.21 11.2 2.0 0.48 10.1 2.0 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DEAD PF00270.29 KND93844.1 - 5.2e-42 143.6 0.2 8.5e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND93844.1 - 6.5e-32 110.2 0.0 2.4e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KND93844.1 - 0.00051 19.8 0.1 0.00076 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KND93844.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KND93844.1 - 0.0014 18.9 0.1 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 KND93844.1 - 0.057 13.4 0.3 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain DUF5393 PF17371.2 KND93844.1 - 0.061 11.4 0.1 0.084 11.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) TniB PF05621.11 KND93844.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 KND93844.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 KND93844.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 KND93844.1 - 0.13 12.5 0.8 0.65 10.3 0.8 2.0 1 1 0 1 1 1 0 AAA domain DUF1688 PF07958.11 KND93845.1 - 3e-179 596.2 0.0 3.4e-179 596.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) EPL1 PF10513.9 KND93846.1 - 1.5e-20 74.2 2.4 1.5e-20 74.2 2.4 2.5 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 KND93847.1 - 6.6e-27 91.0 10.3 1.7e-07 30.3 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KND93847.1 - 1.4e-22 79.9 12.3 3.1e-13 50.0 0.5 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KND93847.1 - 5e-20 69.7 4.2 9e-05 22.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KND93847.1 - 2.8e-18 64.5 9.6 1.7e-06 27.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KND93847.1 - 1.6e-13 50.3 8.8 0.00021 21.1 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KND93847.1 - 6.1e-07 29.8 0.1 0.0014 18.9 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KND93847.1 - 6.1e-06 26.1 6.8 0.0021 18.0 0.2 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KND93847.1 - 0.024 14.8 0.5 0.096 12.9 0.5 2.1 1 1 0 1 1 1 0 Dockerin type I domain Peptidase_M22 PF00814.25 KND93848.1 - 1.1e-76 258.1 0.1 1.4e-76 257.8 0.1 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.15 KND93849.1 - 3.9e-26 91.1 2.7 1.8e-25 89.0 2.7 2.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KND93849.1 - 4.7e-25 87.6 0.0 9.1e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CDC27 PF09507.10 KND93849.1 - 3.7 6.8 7.3 6.1 6.1 7.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NIF PF03031.18 KND93850.1 - 8.7e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.19 KND93851.1 - 2.1e-43 146.7 0.1 3.6e-43 146.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KND93851.1 - 1.1e-14 54.4 0.0 2.9e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KND93851.1 - 3e-09 37.1 0.0 1.3e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND93851.1 - 2.9e-08 33.6 0.3 1.1e-07 31.7 0.1 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND93851.1 - 1.1e-05 25.6 0.0 3.4e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND93851.1 - 0.00062 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_S9 PF00380.19 KND93853.1 - 6e-41 139.8 0.3 9.6e-41 139.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Chorismate_bind PF00425.18 KND93854.1 - 1.4e-64 218.2 0.0 3.6e-63 213.5 0.0 2.5 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KND93854.1 - 1e-22 80.8 0.0 2.3e-21 76.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KND93854.1 - 1.2e-11 45.0 0.0 4.5e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KND93854.1 - 1.6e-05 24.8 0.2 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 RabGAP-TBC PF00566.18 KND93855.1 - 5.4e-36 124.3 0.7 1.2e-35 123.2 0.7 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 KND93855.1 - 1.1e-06 28.2 0.0 0.0067 15.9 0.0 3.0 3 0 0 3 3 3 2 Rab-binding domain (RBD) DUF1754 PF08555.10 KND93856.1 - 3.8e-15 56.5 9.9 6.5e-15 55.7 9.9 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) FBA PF04300.13 KND93856.1 - 0.12 12.0 0.5 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 F-box associated region PBP1_TM PF14812.6 KND93856.1 - 9.2 6.7 12.3 22 5.5 12.3 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LamB_YcsF PF03746.16 KND93857.1 - 5.3e-77 258.7 0.1 6e-77 258.5 0.1 1.0 1 0 0 1 1 1 1 LamB/YcsF family Alpha_GJ PF03229.13 KND93858.1 - 0.011 16.3 2.8 0.011 16.3 2.8 2.9 3 0 0 3 3 3 0 Alphavirus glycoprotein J EphA2_TM PF14575.6 KND93858.1 - 0.2 12.6 0.0 0.35 11.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adaptin_N PF01602.20 KND93859.1 - 2.4e-63 214.5 0.0 4.7e-63 213.5 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KND93859.1 - 0.014 15.4 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UQ_con PF00179.26 KND93861.1 - 4.9e-19 68.4 0.0 7.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KND93861.1 - 0.025 14.9 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain B-block_TFIIIC PF04182.12 KND93862.1 - 3.1e-13 49.7 0.0 6.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KND93862.1 - 0.023 14.6 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 MarR family BSP_II PF05432.11 KND93863.1 - 0.0053 16.5 3.4 0.0074 16.0 3.4 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Spc29 PF17082.5 KND93863.1 - 0.027 14.3 0.4 0.027 14.3 0.4 2.2 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF678 PF05077.12 KND93863.1 - 0.13 12.4 0.3 0.42 10.8 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Ebp2 PF05890.12 KND93864.1 - 1e-95 320.3 11.8 1e-95 320.3 11.8 2.4 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 BUD22 PF09073.10 KND93864.1 - 0.76 9.1 44.9 0.11 11.8 28.6 2.3 2 0 0 2 2 2 0 BUD22 zf-MYND PF01753.18 KND93865.1 - 3.9e-08 33.3 19.6 1.3e-07 31.6 19.6 2.0 1 0 0 1 1 1 1 MYND finger zf-TAZ PF02135.16 KND93865.1 - 0.16 12.5 8.5 0.44 11.0 8.5 1.8 1 0 0 1 1 1 0 TAZ zinc finger CAF20 PF17052.5 KND93865.1 - 1.3 9.1 3.7 0.6 10.2 0.9 1.7 2 0 0 2 2 2 0 Cap associated factor PIG-Y PF15159.6 KND93866.1 - 1.6e-22 80.2 8.4 2.4e-22 79.6 8.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KND93866.1 - 0.038 14.5 1.1 3.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Cation_efflux PF01545.21 KND93867.1 - 3.8e-13 49.6 16.8 5.4e-13 49.1 16.8 1.1 1 0 0 1 1 1 1 Cation efflux family Dynamin_N PF00350.23 KND93868.1 - 4.6e-44 150.4 0.0 9.6e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KND93868.1 - 1.2e-12 47.6 0.0 1.3e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KND93868.1 - 7.4e-07 29.3 0.0 0.088 12.9 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KND93868.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KND93868.1 - 0.059 13.8 0.5 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KND93868.1 - 0.12 12.1 0.6 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 KND93868.1 - 0.17 12.1 0.0 0.63 10.3 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Spb1_C PF07780.12 KND93869.1 - 6.8e-86 287.3 20.5 6.8e-86 287.3 20.5 3.8 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KND93869.1 - 2.6e-55 187.2 0.0 4.9e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KND93869.1 - 2.5e-51 173.7 12.6 2.5e-51 173.7 12.6 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltr_RsmB-F PF01189.17 KND93869.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Voldacs PF03517.13 KND93870.1 - 2.6e-20 73.0 0.3 8.2e-20 71.3 0.3 1.8 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling UQ_con PF00179.26 KND93871.1 - 6.3e-30 103.7 0.0 8.8e-30 103.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spo12 PF05032.12 KND93872.1 - 2.5e-16 59.3 0.9 5.4e-16 58.2 0.9 1.6 1 0 0 1 1 1 1 Spo12 family Sec10 PF07393.11 KND93873.1 - 2.5e-155 518.8 0.0 3.1e-155 518.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KND93873.1 - 2.9e-05 23.9 0.0 7.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND93873.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain AA_kinase PF00696.28 KND93874.1 - 2.3e-38 132.2 0.1 1.1e-37 130.0 0.0 2.1 2 1 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 KND93874.1 - 1.2e-12 47.3 1.1 1.8e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KND93874.1 - 3.3e-12 46.0 2.2 1.2e-07 31.4 0.1 2.5 2 0 0 2 2 2 2 ACT domain CBM_17_28 PF03424.14 KND93874.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) RAMP4 PF06624.12 KND93875.1 - 7e-19 67.7 0.1 8.8e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 KND93876.1 - 3e-08 34.5 5.5 3e-08 34.5 5.5 4.8 3 2 1 4 4 4 1 Small acidic protein family DUF4692 PF15763.5 KND93876.1 - 0.0098 16.4 4.1 0.0098 16.4 4.1 3.3 2 1 0 3 3 3 1 Regulator of human erythroid cell expansion (RHEX) Glyco_hydro_3 PF00933.21 KND93877.1 - 6.3e-39 134.2 0.0 1.2e-38 133.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KND93877.1 - 1.4e-37 129.6 0.0 5.1e-37 127.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KND93877.1 - 3.9e-26 90.9 0.2 7.2e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Mid1 PF12929.7 KND93879.1 - 3.9e-149 497.5 7.5 4.5e-149 497.3 7.5 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KND93879.1 - 0.00026 21.6 6.3 0.027 15.1 2.1 2.6 2 0 0 2 2 2 2 Fz domain EcpB_C PF18649.1 KND93879.1 - 0.081 12.9 0.2 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 EcpB C-terminal domain adh_short PF00106.25 KND93880.1 - 1e-42 145.8 0.6 1.3e-42 145.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND93880.1 - 8.1e-37 127.0 3.3 1.4e-36 126.2 3.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND93880.1 - 2.9e-08 33.8 1.7 6.9e-08 32.6 1.5 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KND93880.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND93880.1 - 6.7e-05 22.9 2.6 0.0027 17.6 2.6 2.1 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KND93880.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KND93880.1 - 0.0027 16.9 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 KND93880.1 - 0.026 14.4 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEM4 PF02602.15 KND93880.1 - 0.047 13.0 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD YjeF_N PF03853.15 KND93880.1 - 0.052 13.4 1.1 0.22 11.4 0.0 2.2 2 1 0 2 2 2 0 YjeF-related protein N-terminus DFP PF04127.15 KND93880.1 - 0.11 12.4 0.5 4.7 7.0 0.1 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 KND93880.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family LDcluster4 PF18306.1 KND93880.1 - 0.2 11.2 2.6 5 6.7 0.0 2.3 2 0 0 2 2 2 0 SLOG cluster4 family RFX_DNA_binding PF02257.15 KND93881.1 - 1.1e-27 96.4 0.2 3.7e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 KND93882.1 - 5.5e-28 96.7 9.2 8.2e-28 96.2 9.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4407 PF14362.6 KND93882.1 - 1.8 7.8 3.2 2.9 7.2 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FAD_binding_4 PF01565.23 KND93883.1 - 2.8e-12 46.6 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain TPALS PF18178.1 KND93884.1 - 0.063 12.7 0.4 0.071 12.5 0.4 1.1 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family DUF410 PF04190.13 KND93885.1 - 1.4e-91 306.9 0.0 1.6e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) AAA_lid_9 PF17871.1 KND93885.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain UPF0220 PF05255.11 KND93887.1 - 5e-65 218.1 3.0 5.6e-65 217.9 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) BNIP3 PF06553.12 KND93887.1 - 0.059 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 BNIP3 DUF5337 PF17272.2 KND93887.1 - 0.31 10.9 3.9 0.27 11.1 1.1 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5337) ABC_membrane PF00664.23 KND93889.1 - 8.3e-53 179.8 36.4 2.6e-34 119.1 17.5 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KND93889.1 - 6.5e-45 153.0 0.0 8e-25 88.0 0.0 2.9 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KND93889.1 - 1.1e-05 25.4 1.1 0.069 13.2 0.4 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KND93889.1 - 1.6e-05 25.4 0.7 0.084 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KND93889.1 - 0.00087 19.2 0.6 0.35 10.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 KND93889.1 - 0.001 18.4 0.0 0.07 12.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SMC_N PF02463.19 KND93889.1 - 0.0018 17.8 1.8 4.9 6.5 0.1 3.4 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain MeaB PF03308.16 KND93889.1 - 0.002 17.1 1.0 0.78 8.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KND93889.1 - 0.002 17.8 1.8 1.1 9.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Presenilin PF01080.17 KND93889.1 - 0.0035 16.2 0.2 0.0035 16.2 0.2 2.8 3 0 0 3 3 3 1 Presenilin AAA_22 PF13401.6 KND93889.1 - 0.0064 16.8 2.0 5.5 7.3 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KND93889.1 - 0.0097 15.6 3.2 1.5 8.5 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KND93889.1 - 0.033 14.0 0.9 9.1 6.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Ploopntkinase3 PF18751.1 KND93889.1 - 0.042 13.8 0.1 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TrwB_AAD_bind PF10412.9 KND93889.1 - 0.058 12.3 2.9 1.9 7.3 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Zip PF02535.22 KND93889.1 - 0.062 12.5 0.1 0.062 12.5 0.1 2.7 3 0 0 3 3 3 0 ZIP Zinc transporter DDHD PF02862.17 KND93889.1 - 0.12 12.5 0.3 1.4 9.1 0.2 2.3 2 0 0 2 2 2 0 DDHD domain NACHT PF05729.12 KND93889.1 - 0.13 12.2 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KND93889.1 - 0.15 11.6 0.9 2.7 7.4 0.2 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KND93889.1 - 0.16 11.3 0.9 16 4.7 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.6 KND93889.1 - 1.5 9.3 4.6 6.4 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP11 PF06644.11 KND93889.1 - 5.1 6.8 7.2 25 4.5 5.0 2.3 2 0 0 2 2 2 0 ATP11 protein TP53IP5 PF15331.6 KND93889.1 - 5.9 7.0 13.5 4 7.5 0.1 2.5 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Dynamin_N PF00350.23 KND93889.1 - 6.5 6.8 18.0 0.15 12.1 0.5 3.7 4 0 0 4 4 3 0 Dynamin family DUF87 PF01935.17 KND93889.1 - 6.9 6.7 15.0 0.29 11.2 0.8 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Cutinase PF01083.22 KND93890.1 - 1.1e-42 145.9 0.1 1.4e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 KND93890.1 - 0.0036 16.9 0.0 0.005 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KND93890.1 - 0.0091 16.6 1.5 0.011 16.3 0.6 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND93890.1 - 0.011 15.5 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 KND93890.1 - 0.023 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 KND93890.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KND93890.1 - 0.045 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_9 PF10081.9 KND93890.1 - 0.05 12.7 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Hydrolase_4 PF12146.8 KND93890.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KND93890.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) 3-dmu-9_3-mt PF06983.13 KND93891.1 - 1.4e-46 157.7 0.0 1.9e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DSX_dimer PF08828.10 KND93891.1 - 0.022 14.4 0.2 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 Doublesex dimerisation domain FG-GAP PF01839.23 KND93892.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat EamA PF00892.20 KND93893.1 - 1e-10 41.9 37.2 1.4e-08 35.0 2.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 KND93893.1 - 2.1e-07 30.5 0.0 2.1e-07 30.5 0.0 2.1 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 KND93893.1 - 7.1e-06 25.7 9.8 3.2e-05 23.6 7.2 3.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3955) UAA PF08449.11 KND93893.1 - 1.2e-05 24.7 11.8 1.2e-05 24.7 11.8 1.6 2 0 0 2 2 2 1 UAA transporter family SLC35F PF06027.12 KND93893.1 - 0.0013 18.3 12.6 0.0013 18.3 12.6 1.5 2 0 0 2 2 2 1 Solute carrier family 35 CRT-like PF08627.10 KND93893.1 - 0.035 13.1 0.0 0.035 13.1 0.0 2.6 3 0 0 3 3 3 0 CRT-like, chloroquine-resistance transporter-like SBP_bac_3 PF00497.20 KND93894.1 - 0.00065 19.2 0.0 0.0018 17.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 KND93894.1 - 0.0018 18.3 0.0 0.0088 16.0 0.0 1.9 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_2 PF13379.6 KND93894.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family NMT1_3 PF16868.5 KND93894.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Fungal_trans_2 PF11951.8 KND93895.1 - 7.3e-49 166.6 1.0 9.8e-48 162.9 1.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93895.1 - 4.3e-07 29.9 7.3 1e-06 28.7 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND93896.1 - 1e-52 178.8 0.1 1.6e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND93896.1 - 1.4e-08 34.8 7.6 0.00083 19.7 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND93896.1 - 0.0005 20.7 6.0 0.57 11.2 1.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND93896.1 - 0.022 15.2 0.2 0.022 15.2 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain TPR_10 PF13374.6 KND93897.1 - 2.3e-32 109.9 0.4 1.9e-09 37.1 0.0 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 KND93897.1 - 1.5e-26 92.5 1.3 1.3e-14 54.2 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KND93897.1 - 1.8e-10 40.1 1.8 0.0097 15.9 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 KND93897.1 - 8e-08 31.8 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 KND93897.1 - 2.8e-05 24.7 2.1 0.057 14.1 0.0 4.2 3 2 0 3 3 2 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KND93897.1 - 0.00019 22.1 1.2 0.0008 20.1 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_1 PF00515.28 KND93897.1 - 0.0027 17.5 0.3 16 5.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 KND93897.1 - 0.0027 18.0 0.0 0.01 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain TPR_4 PF07721.14 KND93897.1 - 0.0031 18.0 0.4 5.7 7.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KND93897.1 - 0.0038 17.2 2.7 21 5.6 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND93897.1 - 0.0057 17.1 0.2 0.04 14.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF676 PF05057.14 KND93897.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 KND93897.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 KND93897.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 KND93897.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) HTH_17 PF12728.7 KND93897.1 - 0.059 13.6 0.2 0.16 12.2 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_16 PF13191.6 KND93897.1 - 0.11 12.8 0.3 0.54 10.6 0.3 2.1 1 1 0 1 1 1 0 AAA ATPase domain Hydrolase_4 PF12146.8 KND93897.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF3506 PF12014.8 KND93898.1 - 2.4e-53 179.9 0.0 6.2e-53 178.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KND93898.1 - 3e-07 30.2 0.4 5.6e-07 29.4 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND93898.1 - 0.00015 21.6 0.2 0.00027 20.7 0.2 1.4 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.18 KND93899.1 - 1.4e-05 25.2 14.2 3.3e-05 23.9 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Stork_head PF10264.9 KND93899.1 - 0.17 12.0 0.0 0.78 10.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Lyase_1 PF00206.20 KND93900.1 - 6.3e-13 48.8 0.2 1.1e-12 48.1 0.2 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KND93900.1 - 1e-12 48.4 0.0 3.8e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Cupin_2 PF07883.11 KND93901.1 - 8e-09 35.1 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KND93901.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KND93901.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain FAA_hydrolase PF01557.18 KND93902.1 - 3.8e-38 131.3 0.0 5.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KND93902.1 - 2.9e-19 69.2 0.0 5.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Pkinase PF00069.25 KND93903.1 - 9.7e-24 84.1 0.0 1.2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND93903.1 - 1.1e-17 64.2 0.0 1.9e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND93903.1 - 0.00015 21.2 0.0 0.00034 20.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KND93903.1 - 0.0024 17.8 0.1 0.0062 16.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KND93903.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND93903.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family VHL_C PF17211.3 KND93903.1 - 0.13 12.3 0.2 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 VHL box domain HET PF06985.11 KND93904.1 - 5.4e-13 49.5 0.4 5.4e-13 49.5 0.4 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S15 PF02129.18 KND93905.1 - 4.7e-40 137.9 0.0 6.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KND93905.1 - 4.3e-35 121.7 0.0 6.2e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 KND93905.1 - 0.0088 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND93905.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Fungal_trans PF04082.18 KND93906.1 - 7.4e-09 35.0 1.1 1.7e-08 33.9 1.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93906.1 - 0.17 12.0 4.4 0.49 10.6 4.4 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_lid_2 PF17863.1 KND93907.1 - 1.5e-06 28.0 0.2 3.7e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain DUF5529 PF17669.1 KND93907.1 - 0.022 14.8 1.3 0.04 13.9 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5529) AMNp_N PF10423.9 KND93907.1 - 0.17 11.5 0.1 1.3 8.6 0.0 2.0 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Ras PF00071.22 KND93908.1 - 1.6e-54 183.8 0.0 2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND93908.1 - 1.4e-30 106.0 0.1 2.5e-30 105.1 0.1 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND93908.1 - 6.4e-12 45.3 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND93908.1 - 5.9e-08 32.8 0.0 9.5e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KND93908.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KND93908.1 - 0.00024 21.1 0.6 0.0039 17.1 0.1 2.5 2 1 1 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 KND93908.1 - 0.00029 20.4 0.4 0.02 14.4 0.4 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KND93908.1 - 0.0012 18.6 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KND93908.1 - 0.0034 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 KND93908.1 - 0.0036 17.3 0.0 0.0081 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KND93908.1 - 0.0074 16.7 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KND93908.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KND93908.1 - 0.015 14.9 0.1 0.085 12.4 0.0 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 KND93908.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND93908.1 - 0.026 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 KND93908.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KND93908.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 KND93908.1 - 0.09 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 KND93908.1 - 0.097 11.8 0.1 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain FeoB_N PF02421.18 KND93908.1 - 0.11 12.0 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 KND93908.1 - 0.13 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KND93908.1 - 0.13 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KND93908.1 - 0.19 12.3 0.0 0.5 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter N-SET PF11764.8 KND93909.1 - 2e-54 184.3 8.2 4.3e-54 183.2 0.0 3.2 3 0 0 3 3 3 2 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KND93909.1 - 1e-26 92.3 0.6 2.2e-26 91.3 0.1 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KND93909.1 - 7.2e-18 65.5 0.1 7.2e-18 65.5 0.1 3.6 3 2 0 3 3 3 1 SET domain DUF3811 PF11656.8 KND93910.1 - 9.4 6.7 7.4 0.33 11.4 0.3 2.2 2 1 1 3 3 3 0 YjbD family (DUF3811) Tropomyosin_1 PF12718.7 KND93911.1 - 7.7e-48 162.3 34.7 3.6e-33 114.7 24.2 2.1 2 0 0 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 KND93911.1 - 4.4e-06 26.2 30.7 0.012 14.9 2.3 3.0 2 1 1 3 3 3 3 Tropomyosin ERM PF00769.19 KND93911.1 - 0.00021 21.2 25.7 0.00028 20.8 25.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TACC_C PF05010.14 KND93911.1 - 0.00029 20.7 19.9 0.00036 20.4 11.0 2.1 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BRE1 PF08647.11 KND93911.1 - 0.0025 17.8 26.9 0.018 15.1 1.8 2.8 2 1 1 3 3 3 2 BRE1 E3 ubiquitin ligase Cep57_CLD_2 PF14197.6 KND93911.1 - 0.0033 17.5 28.7 0.15 12.2 2.1 4.3 3 1 1 4 4 4 2 Centrosome localisation domain of PPC89 GAS PF13851.6 KND93911.1 - 0.0062 15.9 30.6 0.021 14.2 18.2 2.4 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 KND93911.1 - 0.0085 16.3 23.3 0.26 11.5 14.8 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.9 KND93911.1 - 0.0096 16.1 22.0 0.068 13.4 7.7 3.1 2 1 1 3 3 3 2 Predicted coiled-coil domain-containing protein APG6_N PF17675.1 KND93911.1 - 0.011 16.3 36.0 0.039 14.5 9.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region CALCOCO1 PF07888.11 KND93911.1 - 0.013 14.4 19.6 0.093 11.6 10.0 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 KND93911.1 - 0.023 14.8 28.8 0.035 14.2 7.7 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 KND93911.1 - 0.026 13.7 25.1 0.17 11.0 1.1 2.9 2 1 1 3 3 3 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 KND93911.1 - 0.039 14.0 27.9 0.042 13.9 1.2 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 KND93911.1 - 0.046 13.8 32.9 0.15 12.1 10.0 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4686 PF15742.5 KND93911.1 - 0.05 12.7 27.4 0.47 9.5 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) DUF4200 PF13863.6 KND93911.1 - 0.051 14.0 30.1 0.064 13.7 3.1 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) ATG16 PF08614.11 KND93911.1 - 0.052 13.8 32.5 0.37 11.0 21.7 2.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 KND93911.1 - 0.066 13.6 18.5 0.35 11.3 6.4 4.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 KND93911.1 - 0.072 13.5 26.7 0.15 12.5 26.7 1.4 1 1 0 1 1 1 0 Fez1 HMMR_N PF15905.5 KND93911.1 - 0.072 12.5 21.5 0.083 12.3 12.5 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 KND93911.1 - 0.078 13.2 23.4 0.76 10.0 1.5 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KND93911.1 - 0.09 13.9 21.7 1.7 9.8 8.7 3.8 1 1 3 4 4 4 0 Protein SOGA KASH_CCD PF14662.6 KND93911.1 - 0.11 12.4 29.4 4.2 7.1 28.8 2.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Mod_r PF07200.13 KND93911.1 - 0.14 12.3 23.8 0.19 11.9 1.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_GPO PF05929.11 KND93911.1 - 0.14 11.7 15.4 0.12 12.0 8.8 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.12 KND93911.1 - 0.15 12.1 17.3 1.7 8.6 0.4 3.1 1 1 2 3 3 3 0 Laminin Domain II bZIP_1 PF00170.21 KND93911.1 - 0.16 12.1 27.2 2 8.6 6.1 4.5 2 1 2 4 4 4 0 bZIP transcription factor NPV_P10 PF05531.12 KND93911.1 - 0.25 11.8 11.1 4.9 7.7 0.1 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MAD PF05557.13 KND93911.1 - 0.29 9.5 26.6 0.033 12.6 15.5 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein CENP-Q PF13094.6 KND93911.1 - 0.33 11.1 27.0 0.31 11.2 5.4 3.1 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.6 KND93911.1 - 0.36 9.4 22.0 6.5 5.3 22.0 2.1 1 1 0 1 1 1 0 AAA domain Serine_rich PF08824.10 KND93911.1 - 0.4 10.7 10.8 0.12 12.3 7.0 1.9 1 1 1 2 2 2 0 Serine rich protein interaction domain Uso1_p115_C PF04871.13 KND93911.1 - 0.51 10.7 31.7 1.3e+02 2.9 2.6 3.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CLZ PF16526.5 KND93911.1 - 0.7 10.3 22.0 1.7 9.0 0.7 3.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Surfac_D-trimer PF09006.11 KND93911.1 - 0.71 9.8 5.5 2.7 8.0 0.0 3.1 4 0 0 4 4 2 0 Lung surfactant protein D coiled-coil trimerisation TANGO2 PF05742.12 KND93911.1 - 0.74 9.8 6.1 0.6 10.1 5.0 1.5 1 1 0 1 1 1 0 Transport and Golgi organisation 2 SHE3 PF17078.5 KND93911.1 - 0.78 9.4 22.1 0.2 11.3 0.8 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 KND93911.1 - 0.81 9.0 26.7 1.9 7.7 14.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) JAKMIP_CC3 PF16034.5 KND93911.1 - 0.82 9.6 27.1 0.17 11.8 6.3 3.1 1 1 2 3 3 3 0 JAKMIP CC3 domain Alanine_zipper PF11839.8 KND93911.1 - 0.97 9.8 10.1 1.9 8.9 0.3 3.5 3 1 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein CEP209_CC5 PF16574.5 KND93911.1 - 0.99 9.6 21.5 0.63 10.2 5.6 2.9 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 Spc7 PF08317.11 KND93911.1 - 1.2 8.0 30.2 0.92 8.3 10.0 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein HOOK PF05622.12 KND93911.1 - 1.2 7.2 27.2 1.8 6.6 3.0 2.2 1 1 0 2 2 2 0 HOOK protein CtIP_N PF10482.9 KND93911.1 - 1.3 9.1 20.6 3.2 7.8 0.9 2.9 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Lebercilin PF15619.6 KND93911.1 - 1.3 8.6 31.8 91 2.6 31.8 2.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Syntaxin-6_N PF09177.11 KND93911.1 - 1.4 9.5 16.5 0.66 10.6 8.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3287 PF11690.8 KND93911.1 - 1.5 8.6 6.0 13 5.6 0.2 3.1 2 2 1 4 4 4 0 Protein of unknown function (DUF3287) DUF724 PF05266.14 KND93911.1 - 1.5 8.7 23.9 0.3 10.9 6.0 2.9 1 1 1 2 2 1 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 KND93911.1 - 1.6 9.1 22.5 4.4 7.7 1.2 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF677 PF05055.12 KND93911.1 - 1.9 7.3 10.8 0.48 9.3 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DUF2730 PF10805.8 KND93911.1 - 2.3 8.4 9.7 5.9 7.1 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Prefoldin_2 PF01920.20 KND93911.1 - 2.4 8.1 32.6 2.3 8.2 14.7 3.7 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 KND93911.1 - 3.2 6.9 18.1 5.6 6.1 11.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 KND93911.1 - 3.7 8.0 23.9 3.9 7.9 0.6 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) GIT_CC PF16559.5 KND93911.1 - 3.9 7.4 20.4 5.9 6.8 6.8 4.2 2 2 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4472 PF14739.6 KND93911.1 - 3.9 8.2 25.5 6.5 7.5 1.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) YabA PF06156.13 KND93911.1 - 4 8.1 21.7 12 6.6 0.6 3.0 2 1 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KND93911.1 - 4 7.9 40.3 3.1 8.3 3.4 3.9 1 1 2 3 3 3 0 Cell division protein ZapB Dynamitin PF04912.14 KND93911.1 - 4.6 6.5 25.5 3.1 7.0 1.7 2.4 1 1 0 1 1 1 0 Dynamitin Leu_zip PF15294.6 KND93911.1 - 4.9 6.6 23.5 1.4 8.3 15.5 2.0 1 1 1 2 2 2 0 Leucine zipper UPF0242 PF06785.11 KND93911.1 - 5.9 6.9 30.1 0.46 10.6 12.0 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus T3SSipB PF16535.5 KND93911.1 - 6 7.3 19.5 10 6.6 1.5 3.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB TMF_DNA_bd PF12329.8 KND93911.1 - 6.5 6.8 32.1 6.6 6.8 1.3 3.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.9 KND93911.1 - 6.7 6.6 29.7 6.1 6.7 5.8 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain DHR10 PF18595.1 KND93911.1 - 7.3 6.7 33.6 13 5.9 22.8 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain PilJ PF13675.6 KND93911.1 - 7.7 6.6 12.9 1.2 9.2 1.3 3.1 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_2 PF07716.15 KND93911.1 - 7.7 6.7 33.0 2 8.5 4.1 5.1 3 2 2 5 5 5 0 Basic region leucine zipper SlyX PF04102.12 KND93911.1 - 8 7.2 23.8 5.7 7.6 4.9 3.5 2 1 1 3 3 3 0 SlyX Paralemmin PF03285.15 KND93911.1 - 8 5.9 19.8 5.4 6.5 1.8 2.2 2 0 0 2 2 2 0 Paralemmin V_ATPase_I PF01496.19 KND93911.1 - 8.2 4.2 18.1 1.8 6.4 5.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Nop25 PF09805.9 KND93912.1 - 4.9e-42 143.6 12.9 4.9e-42 143.6 12.9 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Dickkopf_N PF04706.12 KND93913.1 - 0.011 16.2 2.9 0.027 15.0 2.9 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF4202 PF13875.6 KND93914.1 - 9e-68 227.8 0.0 1e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) CCDC24 PF15669.5 KND93915.1 - 0.042 13.7 1.7 0.075 12.9 1.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Sterol-sensing PF12349.8 KND93917.1 - 2.7e-35 121.5 10.9 5.5e-35 120.5 10.9 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KND93917.1 - 8.6e-11 40.7 2.1 1.1e-10 40.3 2.1 1.1 1 0 0 1 1 1 1 Patched family 14-3-3 PF00244.20 KND93918.1 - 1.4e-06 28.0 0.1 2.1e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 14-3-3 protein 2-Hacid_dh_C PF02826.19 KND93920.1 - 6.6e-52 175.4 0.0 1.4e-51 174.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KND93920.1 - 2e-14 53.4 0.0 3.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KND93920.1 - 5e-05 23.5 0.0 9.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.6 KND93921.1 - 6.9e-63 212.9 38.3 8.7e-63 212.6 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND93921.1 - 1.2e-25 90.0 25.8 1.2e-25 90.0 25.8 2.1 2 1 0 2 2 2 1 Amino acid permease EXS PF03124.14 KND93922.1 - 1.5e-99 333.4 34.1 1.9e-99 333.1 34.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KND93922.1 - 2e-77 261.7 2.4 2e-77 261.7 2.4 1.8 2 0 0 2 2 2 1 SPX domain Cwf_Cwc_15 PF04889.12 KND93922.1 - 0.11 12.2 8.9 0.19 11.4 8.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EF-1_beta_acid PF10587.9 KND93922.1 - 3.4 8.2 7.4 8.3 7.0 7.4 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region ORC2 PF04084.14 KND93924.1 - 1.5e-111 372.5 0.0 2.7e-111 371.7 0.0 1.4 1 1 0 1 1 1 1 Origin recognition complex subunit 2 DDE_5 PF13546.6 KND93924.1 - 0.035 13.5 1.6 0.1 11.9 1.6 1.9 1 0 0 1 1 1 0 DDE superfamily endonuclease AT_hook PF02178.19 KND93924.1 - 0.094 12.6 7.9 0.059 13.3 4.5 2.6 2 0 0 2 2 2 0 AT hook motif RNA_pol_Rpb1_5 PF04998.17 KND93925.1 - 5.9e-88 294.7 0.0 1e-87 294.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KND93925.1 - 1.9e-67 226.6 0.8 3.8e-67 225.6 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 KND93925.1 - 9.9e-38 130.2 0.7 1.1e-36 126.8 0.1 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 KND93925.1 - 5.4e-31 107.7 0.0 1.7e-30 106.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KND93925.1 - 9.3e-17 60.9 0.0 2.8e-16 59.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Fungal_trans PF04082.18 KND93926.1 - 9.6e-34 116.6 2.3 2.9e-33 115.0 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND93926.1 - 1.5e-06 28.2 9.8 2.8e-06 27.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KND93926.1 - 0.0032 17.5 3.7 0.0032 17.5 3.7 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 KND93926.1 - 0.26 11.4 7.6 0.094 12.8 4.1 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3744 PF12558.8 KND93926.1 - 0.28 12.0 1.8 0.51 11.1 0.9 1.9 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter Malic_M PF03949.15 KND93927.1 - 8.9e-89 297.2 0.0 1.4e-88 296.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KND93927.1 - 8.9e-72 240.7 0.0 1.4e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_16 PF00722.21 KND93928.1 - 2.9e-17 62.7 0.5 5.5e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 GAS2 PF02187.17 KND93929.1 - 4.8e-07 29.8 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Ribosomal_L4 PF00573.22 KND93930.1 - 7.2e-36 123.7 0.0 9.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KND93930.1 - 1e-27 96.0 1.2 2.5e-27 94.7 1.2 1.7 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Shadoo PF14999.6 KND93931.1 - 0.5 10.5 5.6 1.2 9.2 5.6 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective POT1 PF02765.17 KND93932.1 - 5.2e-12 45.8 0.0 1.7e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 KND93933.1 - 2.4e-32 112.1 0.1 2.4e-17 62.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KND93933.1 - 6.6e-14 51.8 0.0 1.2e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND93933.1 - 9.6e-14 51.3 1.2 5.8e-07 29.1 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND93933.1 - 3.5e-09 36.7 0.0 0.00031 20.4 0.0 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KND93933.1 - 1.3e-08 34.9 0.0 1.5e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KND93933.1 - 1.9e-08 33.9 0.0 4.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KND93933.1 - 1.7e-07 30.7 0.1 8e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 KND93933.1 - 1.8e-07 31.3 0.9 1.5e-05 25.0 0.0 3.3 3 2 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KND93933.1 - 3.6e-06 25.9 0.1 0.019 13.7 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 KND93933.1 - 3.8e-05 23.1 0.1 0.00046 19.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KND93933.1 - 0.0001 22.8 0.3 0.055 14.0 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KND93933.1 - 0.00056 19.3 0.0 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 KND93933.1 - 0.0012 18.0 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 KND93933.1 - 0.0015 17.7 0.3 0.021 13.9 0.0 2.6 2 1 1 3 3 3 1 FAD binding domain Glu_dehyd_C PF16912.5 KND93933.1 - 0.0028 17.2 0.0 0.61 9.5 0.0 2.3 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KND93933.1 - 0.0047 17.0 0.0 0.37 10.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KND93933.1 - 0.029 14.0 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 KND93933.1 - 0.083 12.2 0.2 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KND93933.1 - 0.093 12.1 0.1 7.8 5.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MMR_HSR1 PF01926.23 KND93934.1 - 2.2e-16 59.9 0.1 3.4e-15 56.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND93934.1 - 8.5e-08 31.9 0.2 9.8e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KND93934.1 - 3.9e-07 30.1 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KND93934.1 - 0.0057 16.7 0.1 0.11 12.6 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AIG1 PF04548.16 KND93934.1 - 0.025 13.9 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 AIG1 family DUF3046 PF11248.8 KND93934.1 - 0.89 10.0 3.1 46 4.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3046) DUF3320 PF11784.8 KND93935.1 - 3.5e-05 23.6 0.1 0.00024 21.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3320) HAD PF12710.7 KND93936.1 - 0.0003 21.3 0.0 0.0036 17.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_10 PF13374.6 KND93937.1 - 1.4e-56 186.9 13.4 2.1e-10 40.1 0.1 6.6 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 KND93937.1 - 7.5e-49 163.9 24.2 1.4e-15 57.3 1.2 5.2 2 1 4 6 6 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 KND93937.1 - 2.9e-27 93.3 26.9 0.00023 20.9 0.2 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 KND93937.1 - 7e-23 78.9 15.2 0.002 18.0 0.0 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 KND93937.1 - 9.4e-21 72.3 20.0 0.0085 16.2 0.3 7.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 KND93937.1 - 1.3e-18 65.5 18.0 0.019 15.0 0.2 6.8 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KND93937.1 - 1.9e-14 53.8 1.9 2.9e-07 30.2 0.1 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_17 PF13431.6 KND93937.1 - 1.3e-09 37.8 7.8 3.6 8.2 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KND93937.1 - 2.4e-08 33.8 0.0 5.6 7.9 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KND93937.1 - 7.3e-08 32.9 13.8 0.0051 17.4 1.3 5.7 3 2 1 4 4 4 3 Tetratricopeptide repeat DUF676 PF05057.14 KND93937.1 - 5.3e-06 26.1 0.0 9.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_19 PF14559.6 KND93937.1 - 1.6e-05 25.4 8.3 0.66 10.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat PGAP1 PF07819.13 KND93937.1 - 0.0002 21.2 0.1 0.0004 20.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein TPR_11 PF13414.6 KND93937.1 - 0.00025 20.7 16.6 5 6.9 0.2 6.4 6 0 0 6 6 6 1 TPR repeat TPR_3 PF07720.12 KND93937.1 - 0.0024 17.8 2.1 1.7 8.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 KND93937.1 - 0.0034 17.5 5.5 40 4.8 0.0 5.5 5 0 0 5 5 5 0 PPR repeat TPR_14 PF13428.6 KND93937.1 - 0.0052 17.5 18.3 6.6 7.8 0.3 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KND93937.1 - 0.016 15.8 1.1 0.097 13.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4810 PF16068.5 KND93937.1 - 0.028 15.0 3.7 1.1e+02 3.5 0.0 5.2 6 0 0 6 6 5 0 Domain of unknown function (DUF4810) NB-ARC PF00931.22 KND93937.1 - 0.072 12.3 0.0 0.22 10.7 0.0 1.8 1 1 1 2 2 2 0 NB-ARC domain RPN6_C_helix PF18503.1 KND93937.1 - 0.073 12.8 4.9 65 3.4 0.1 4.5 4 0 0 4 4 4 0 26S proteasome subunit RPN6 C-terminal helix domain TPR_21 PF09976.9 KND93937.1 - 0.076 12.7 9.8 20 4.8 0.0 5.2 1 1 4 5 5 5 0 Tetratricopeptide repeat-like domain YjeF_N PF03853.15 KND93937.1 - 0.14 12.0 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus Phage_T4_Ndd PF06591.11 KND93937.1 - 0.15 11.9 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) AAA_16 PF13191.6 KND93937.1 - 0.26 11.7 2.1 1.1 9.6 0.4 2.8 2 2 0 2 2 2 0 AAA ATPase domain Methyltransf_11 PF08241.12 KND93938.1 - 1.4e-11 44.9 0.1 2.5e-11 44.1 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND93938.1 - 1.4e-10 41.7 0.1 4.1e-10 40.2 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND93938.1 - 3.2e-05 23.8 0.0 7.8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND93938.1 - 0.00018 21.4 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND93938.1 - 0.00042 19.7 0.0 0.00059 19.2 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KND93938.1 - 0.019 15.7 0.0 0.037 14.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KND93938.1 - 0.087 12.4 0.1 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain PAC3 PF10178.9 KND93939.1 - 0.0018 18.4 0.0 0.0031 17.6 0.0 1.4 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 Mito_carr PF00153.27 KND93940.1 - 5.1e-14 51.9 2.1 3.4e-05 23.7 0.0 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein COMPASS-Shg1 PF05205.12 KND93941.1 - 4.7e-24 85.1 0.4 4.7e-24 85.1 0.4 2.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 TPT PF03151.16 KND93942.1 - 4.3e-24 85.4 15.9 5.8e-24 84.9 15.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 KND93942.1 - 0.067 12.4 17.3 0.19 10.9 17.3 1.7 1 1 0 1 1 1 0 UAA transporter family EamA PF00892.20 KND93942.1 - 2.1 8.6 39.6 1 9.5 12.5 2.9 3 0 0 3 3 3 0 EamA-like transporter family TauD PF02668.16 KND93943.1 - 3.1e-38 132.1 0.1 4.2e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KND93943.1 - 1.9e-11 44.5 0.5 5.2e-11 43.0 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 KND93943.1 - 0.04 13.0 0.1 0.081 12.0 0.0 1.5 2 0 0 2 2 2 0 CsiD adh_short_C2 PF13561.6 KND93944.1 - 1.5e-23 83.6 8.6 1.6e-22 80.2 8.6 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND93944.1 - 2.1e-21 76.3 8.9 1.1e-19 70.7 8.9 2.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND93944.1 - 4.5e-05 23.4 0.4 0.00011 22.2 0.1 1.7 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KND93944.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KND93944.1 - 0.14 12.1 0.5 0.28 11.0 0.5 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 KND93945.1 - 1.7e-20 73.6 0.0 1.8e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CENP-S PF15630.6 KND93946.1 - 3.7e-34 116.9 0.0 5.1e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KND93946.1 - 6.2e-07 29.5 0.0 7.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 KND93946.1 - 0.049 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit WSC PF01822.19 KND93947.1 - 3.5e-52 174.5 48.6 1.5e-17 63.5 9.8 3.6 3 0 0 3 3 3 3 WSC domain peroxidase PF00141.23 KND93947.1 - 4.8e-23 82.1 0.0 1e-22 81.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Caskin-Pro-rich PF16907.5 KND93947.1 - 0.19 12.3 3.3 0.5 10.9 3.3 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins MARVEL PF01284.23 KND93948.1 - 0.022 14.8 21.3 0.051 13.6 21.6 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF3422 PF11902.8 KND93948.1 - 0.6 9.2 3.0 1.9 7.5 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) Phage_holin_8 PF16931.5 KND93948.1 - 9.3 6.2 11.3 44 4.1 0.4 2.4 1 1 1 2 2 2 0 Putative phage holin DUF3402 PF11882.8 KND93949.1 - 1.5e-205 683.7 0.0 2e-205 683.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KND93949.1 - 1.7e-92 309.7 0.1 2.6e-92 309.1 0.1 1.2 1 0 0 1 1 1 1 N1221-like protein CDC45 PF02724.14 KND93949.1 - 0.32 9.2 5.4 0.5 8.6 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KND93949.1 - 9.2 5.6 13.6 20 4.5 13.6 1.5 1 0 0 1 1 1 0 SDA1 DUF2011 PF09428.10 KND93950.1 - 6e-21 74.5 0.9 4e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Arr-ms PF12120.8 KND93950.1 - 0.048 13.9 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Rifampin ADP-ribosyl transferase DUF4407 PF14362.6 KND93950.1 - 0.22 10.9 4.3 0.28 10.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDT80_PhoG PF05224.12 KND93952.1 - 9.5e-33 114.0 0.0 1.6e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family IBR PF01485.21 KND93953.1 - 3.2e-22 78.5 33.2 3.4e-15 56.0 2.5 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KND93953.1 - 6.3e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 KND93953.1 - 4.3e-05 23.5 29.8 0.00022 21.2 6.4 3.7 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 KND93953.1 - 0.00018 21.8 8.0 0.00018 21.8 8.0 4.0 3 1 1 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 KND93953.1 - 0.00067 19.4 8.1 0.0023 17.6 8.1 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KND93953.1 - 0.0049 17.0 2.4 0.0049 17.0 2.4 4.1 4 1 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KND93953.1 - 0.0077 16.2 8.4 0.0077 16.2 8.4 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KND93953.1 - 0.016 15.1 8.9 0.016 15.1 8.9 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PALP PF00291.25 KND93955.1 - 2.3e-66 224.2 0.0 2.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4679 PF15728.5 KND93955.1 - 0.084 11.9 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) ELFV_dehydrog PF00208.21 KND93956.1 - 3.6e-84 282.3 3.7 4.6e-84 282.0 3.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KND93956.1 - 7.6e-51 171.4 0.0 2.7e-50 169.6 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 KND93956.1 - 0.008 16.6 0.1 0.018 15.4 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding CoA_transf_3 PF02515.17 KND93957.1 - 5.5e-69 233.1 0.1 7e-69 232.7 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF2484 PF10658.9 KND93957.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) Dynamin_M PF01031.20 KND93958.1 - 2.3e-100 335.5 0.3 3.8e-100 334.8 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KND93958.1 - 2.3e-56 190.5 0.0 4.5e-56 189.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KND93958.1 - 9.5e-30 102.6 6.0 2.2e-29 101.5 6.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KND93958.1 - 6.7e-06 26.2 0.2 0.00012 22.1 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KND93958.1 - 0.28 10.8 3.3 5.9 6.5 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain WD40 PF00400.32 KND93960.1 - 3.6e-09 37.1 11.8 0.0019 19.0 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40_3 PF15911.5 KND93960.1 - 0.041 13.9 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat ANAPC9 PF12856.7 KND93961.1 - 0.33 11.2 1.5 0.84 9.8 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 CAS_CSE1 PF03378.15 KND93962.1 - 2.2e-158 527.4 0.0 1e-157 525.2 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 KND93962.1 - 4.5e-149 496.3 1.5 6.4e-149 495.8 1.5 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 KND93962.1 - 1.8e-13 50.2 0.0 5.8e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_N PF14500.6 KND93962.1 - 0.1 12.2 0.5 8.9 5.8 0.0 3.2 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 KND93962.1 - 0.24 10.6 2.8 1.4 8.2 0.0 3.2 3 1 1 4 4 4 0 V-ATPase subunit H DUF3384 PF11864.8 KND93963.1 - 7.8e-150 499.9 0.9 2.7e-149 498.1 0.2 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KND93963.1 - 4.7e-54 182.8 0.0 8.4e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KND93963.1 - 2e-36 125.8 0.2 3.2e-30 105.5 0.0 4.2 4 0 0 4 4 4 3 Tuberin ABC_tran PF00005.27 KND93964.1 - 3.5e-14 53.5 0.0 2.3e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KND93964.1 - 2.8e-11 43.8 1.7 0.00013 21.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 KND93964.1 - 0.00058 17.5 0.2 0.00077 17.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 KND93964.1 - 0.00096 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KND93964.1 - 0.0037 17.8 0.0 0.0054 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KND93964.1 - 0.0047 16.4 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KND93964.1 - 0.01 16.2 0.5 0.039 14.3 0.5 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KND93964.1 - 0.011 16.1 0.0 0.07 13.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KND93964.1 - 0.012 15.8 0.2 0.026 14.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KND93964.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 KND93964.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KND93964.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KND93964.1 - 0.021 15.1 0.1 0.041 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 KND93964.1 - 0.033 14.4 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 KND93964.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KND93964.1 - 0.06 13.4 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 KND93964.1 - 0.077 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KND93964.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 KND93964.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_33 PF13671.6 KND93964.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KND93964.1 - 0.12 12.3 0.2 0.78 9.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KND93964.1 - 0.19 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain CENP-I PF07778.11 KND93965.1 - 2.4e-30 105.8 0.0 1.4e-28 99.9 0.0 2.1 1 1 0 1 1 1 1 Mis6 DNA_pol_E_B PF04042.16 KND93966.1 - 5.4e-48 163.1 0.0 7e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KND93966.1 - 1.7e-39 134.9 0.0 2.5e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain HGTP_anticodon2 PF12745.7 KND93967.1 - 6.1e-80 268.5 3.2 6.1e-80 268.5 3.2 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 KND93967.1 - 7.1e-74 248.5 2.1 3.9e-35 121.5 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 KND93967.1 - 4e-45 154.1 0.0 2.8e-20 72.7 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KND93967.1 - 2.7e-15 56.5 0.5 3.7e-14 52.7 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 KND93967.1 - 6.1e-10 39.4 0.0 1.8e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.23 KND93967.1 - 0.00013 21.9 4.7 0.042 13.8 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KND93967.1 - 0.056 13.0 1.7 1 8.8 0.0 3.0 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Med21 PF11221.8 KND93967.1 - 0.27 11.5 11.0 0.035 14.4 6.2 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Cut12 PF11500.8 KND93968.1 - 7.6e-43 145.9 13.3 7.6e-43 145.9 13.3 3.2 3 0 0 3 3 3 1 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.12 KND93968.1 - 0.34 10.8 12.3 7.8 6.5 0.7 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Rootletin PF15035.6 KND93968.1 - 4.8 7.2 38.0 0.14 12.2 3.4 4.3 2 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion MMR_HSR1_Xtn PF16897.5 KND93969.1 - 4.7e-35 119.8 2.1 8.8e-35 118.9 0.8 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KND93969.1 - 2.3e-20 72.8 0.0 4.6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KND93969.1 - 4.2e-19 68.3 0.2 9.1e-19 67.3 0.0 1.6 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 KND93969.1 - 1.6e-12 47.2 0.0 2.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KND93969.1 - 0.00019 21.6 0.4 0.046 13.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 KND93969.1 - 0.11 11.5 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KND93969.1 - 0.13 11.3 0.0 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain Torus PF16131.5 KND93970.1 - 1e-41 142.0 0.2 1e-41 142.0 0.2 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 KND93970.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KND93970.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 KND93970.1 - 0.011 15.8 0.6 0.011 15.8 0.6 1.9 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 KND93970.1 - 0.12 12.3 0.5 0.23 11.4 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAT PF02259.23 KND93972.1 - 6.5e-74 249.2 8.4 1.4e-73 248.1 8.4 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KND93972.1 - 5.1e-30 105.1 0.0 1.3e-29 103.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KND93972.1 - 2.1e-06 27.4 0.2 4.9e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 KND93972.1 - 0.0024 17.8 1.5 0.55 10.5 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KND93972.1 - 0.025 14.4 1.6 4.6 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KND93972.1 - 0.052 14.0 0.7 99 3.7 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND93972.1 - 0.18 12.1 1.8 1 9.7 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.22 KND93972.1 - 0.21 11.9 0.9 3 8.4 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Urb2 PF10441.9 KND93972.1 - 0.89 9.4 7.6 2 8.3 0.0 4.8 5 2 0 5 5 5 0 Urb2/Npa2 family GGACT PF06094.12 KND93973.1 - 1.2e-19 71.1 0.4 1.4e-19 70.8 0.4 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF1757 PF08560.10 KND93974.1 - 0.013 15.5 0.8 0.079 13.0 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1757) DUF3137 PF11335.8 KND93974.1 - 0.24 11.3 0.0 0.34 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) AMP-binding PF00501.28 KND93975.1 - 7.4e-35 120.3 0.0 9.7e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KND93975.1 - 9.8e-08 31.8 1.3 2e-07 30.8 1.3 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KND93975.1 - 0.0001 23.2 0.2 0.0003 21.7 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMI1_KNR4 PF09346.10 KND93976.1 - 1.2e-32 113.1 0.0 2.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.14 KND93977.1 - 3.9e-48 162.9 2.2 9.9e-48 161.6 0.9 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KND93977.1 - 1.2e-10 41.2 1.2 2.7e-10 40.0 1.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 KND93977.1 - 0.0014 17.3 0.8 0.0014 17.3 0.8 2.3 3 0 0 3 3 3 1 Centromere/kinetochore Zw10 YcbB PF08664.10 KND93977.1 - 0.015 15.4 0.2 0.037 14.1 0.2 1.7 1 0 0 1 1 1 0 YcbB domain Swi5 PF07061.11 KND93977.1 - 0.14 12.3 0.2 0.45 10.6 0.2 2.0 1 0 0 1 1 1 0 Swi5 Glyco_hydro_61 PF03443.14 KND93978.1 - 2.9e-05 24.1 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 KND93978.1 - 0.0072 17.0 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF3433 PF11915.8 KND93979.1 - 5e-40 135.9 13.6 1.9e-23 82.7 0.2 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_transf_9 PF01075.17 KND93979.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Metallophos PF00149.28 KND93980.1 - 1.9e-15 57.9 0.6 2.7e-15 57.4 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Latarcin PF10279.9 KND93980.1 - 0.059 13.8 0.0 13 6.3 0.0 2.4 2 1 0 2 2 2 0 Latarcin precursor Pet127 PF08634.10 KND93981.1 - 7.4e-118 392.9 1.6 1.1e-117 392.4 1.6 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Iso_dh PF00180.20 KND93982.1 - 6.5e-84 282.0 0.0 7.5e-84 281.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pol_alpha_B_N PF08418.10 KND93983.1 - 5.3e-76 255.8 0.0 7.1e-76 255.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KND93983.1 - 1.3e-40 139.0 0.0 2.4e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Rop-like PF05082.13 KND93983.1 - 0.091 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 Rop-like MFAP1 PF06991.11 KND93984.1 - 9e-69 231.6 29.4 9e-69 231.6 29.4 3.0 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing DNA_pol_phi PF04931.13 KND93984.1 - 0.51 8.4 24.8 0.95 7.5 24.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi GATA PF00320.27 KND93985.1 - 0.00056 19.5 1.8 0.87 9.2 0.1 2.6 2 0 0 2 2 2 2 GATA zinc finger polyprenyl_synt PF00348.17 KND93987.1 - 2.8e-88 295.3 0.1 3.5e-88 295.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase YkyB PF14177.6 KND93987.1 - 0.046 14.0 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 YkyB-like protein ANAPC8 PF04049.13 KND93988.1 - 7.2e-58 194.6 0.3 1.9e-57 193.2 0.0 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 KND93988.1 - 1.5e-19 68.5 9.8 0.00059 19.8 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 KND93988.1 - 2.4e-19 68.3 5.4 9.2e-05 22.1 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND93988.1 - 4.7e-11 41.9 16.0 0.049 13.8 0.0 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 KND93988.1 - 5.8e-08 32.3 0.6 3e-06 26.8 0.1 3.2 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 KND93988.1 - 6.3e-07 29.7 24.0 0.017 15.9 0.1 9.0 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND93988.1 - 6.6e-07 29.9 19.6 4.8e-05 23.9 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 KND93988.1 - 0.0001 22.5 22.3 0.18 12.1 0.1 7.1 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KND93988.1 - 0.00024 21.3 0.2 6.5 7.4 0.0 4.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KND93988.1 - 0.0013 18.6 7.3 0.032 14.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 KND93988.1 - 0.0025 17.9 2.6 0.076 13.1 0.1 3.2 2 1 0 3 3 2 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 KND93988.1 - 0.009 16.5 18.2 5.9 7.5 0.0 7.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KND93988.1 - 0.038 13.4 0.3 0.038 13.4 0.3 2.8 3 0 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 KND93988.1 - 0.04 13.8 2.4 7.4 6.6 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KND93988.1 - 0.059 13.6 10.7 0.88 9.8 0.6 5.0 4 1 2 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Say1_Mug180 PF10340.9 KND93988.1 - 0.088 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase JHD PF17811.1 KND93988.1 - 0.16 12.5 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 Jumonji helical domain TPR_6 PF13174.6 KND93988.1 - 0.78 10.5 21.3 17 6.3 0.3 8.3 11 0 0 11 11 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND93988.1 - 3.2 8.0 19.3 13 6.0 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat RmlD_sub_bind PF04321.17 KND93989.1 - 1.2e-51 175.6 0.1 1.5e-51 175.2 0.1 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KND93989.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND93989.1 - 3.9e-09 36.4 0.1 1e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KND93989.1 - 4.4e-09 35.9 0.6 4.5e-06 26.0 0.1 3.3 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KND93989.1 - 3.6e-08 32.9 0.1 1.6e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KND93989.1 - 0.00019 20.5 0.0 0.00068 18.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 KND93989.1 - 0.13 12.2 2.7 2.1 8.2 0.2 2.4 1 1 1 2 2 2 0 KR domain PH PF00169.29 KND93990.1 - 7e-05 23.3 0.1 0.00015 22.3 0.1 1.5 1 0 0 1 1 1 1 PH domain DHFR_2 PF06442.11 KND93991.1 - 0.1 12.5 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 R67 dihydrofolate reductase Vps54 PF07928.12 KND93992.1 - 1e-51 174.8 1.0 2e-51 173.9 0.1 2.0 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KND93992.1 - 8.3e-06 25.3 0.5 2e-05 24.1 0.5 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KND93992.1 - 7.2e-05 22.7 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 KND93992.1 - 0.07 13.0 0.4 0.67 9.8 0.2 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Helo_like_N PF17111.5 KND93992.1 - 0.071 12.5 3.0 0.66 9.3 0.2 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins COG2 PF06148.11 KND93992.1 - 0.31 11.1 2.2 1 9.4 0.9 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Troponin-I_N PF11636.8 KND93992.1 - 7.1 6.7 7.8 0.96 9.4 1.2 2.7 2 0 0 2 2 2 0 Troponin I residues 1-32 MSL2-CXC PF16682.5 KND93993.1 - 0.56 10.4 3.8 0.29 11.3 0.6 2.1 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Y_phosphatase2 PF03162.13 KND93994.1 - 5.6e-42 143.1 0.0 8.3e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KND93994.1 - 1.3e-09 38.4 0.0 3.1e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KND93994.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 KND93994.1 - 0.039 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain NAD_binding_6 PF08030.12 KND93995.1 - 1.3e-11 44.9 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Iron_permease PF04120.12 KND93996.1 - 7.7e-38 129.2 15.0 5.5e-20 71.4 0.1 4.2 3 1 1 4 4 4 4 Low affinity iron permease DUF2839 PF10999.8 KND93996.1 - 0.0028 18.0 0.5 0.0028 18.0 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2839) V_ATPase_I PF01496.19 KND93996.1 - 0.58 8.0 4.1 5.7 4.7 0.1 2.4 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Ank_2 PF12796.7 KND93997.1 - 3.2e-115 376.9 16.1 7.5e-20 71.3 0.0 5.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND93997.1 - 2.5e-53 177.8 0.8 9.8e-09 35.6 0.0 7.3 7 2 1 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND93997.1 - 8.3e-43 139.5 1.1 0.00057 20.1 0.0 11.7 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KND93997.1 - 4e-42 141.7 7.4 1.2e-05 25.5 0.1 9.9 2 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 KND93997.1 - 8.7e-40 133.5 1.2 0.0022 18.4 0.0 11.3 12 0 0 12 12 12 9 Ankyrin repeat Clr5 PF14420.6 KND93997.1 - 2.9e-12 46.6 2.7 6.1e-12 45.6 2.7 1.5 1 0 0 1 1 1 1 Clr5 domain R3H PF01424.22 KND93997.1 - 0.01 15.8 1.3 4.7 7.3 0.0 4.5 5 0 0 5 5 5 1 R3H domain DUF1843 PF08898.10 KND93997.1 - 0.02 15.4 4.4 50 4.5 0.1 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF1843) FliT PF05400.13 KND93997.1 - 0.52 11.2 2.8 90 4.0 0.0 4.4 4 1 0 4 4 4 0 Flagellar protein FliT AAA PF00004.29 KND93998.1 - 5.2e-34 117.5 0.0 7.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND93998.1 - 8.7e-10 39.2 0.6 1.8e-06 28.5 0.1 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 KND93998.1 - 7.2e-07 29.3 0.0 2.6e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND93998.1 - 3.5e-06 27.2 0.0 6.4e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KND93998.1 - 7.1e-06 25.7 0.1 1.6e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KND93998.1 - 8.3e-06 26.1 0.3 0.0041 17.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KND93998.1 - 5.1e-05 22.6 0.0 7.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 KND93998.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 KND93998.1 - 0.0004 19.9 0.2 0.0082 15.7 0.1 2.5 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 KND93998.1 - 0.00042 20.4 0.0 0.00079 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND93998.1 - 0.00049 19.9 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KND93998.1 - 0.00087 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KND93998.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KND93998.1 - 0.0013 18.2 0.0 0.017 14.5 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 KND93998.1 - 0.0014 18.9 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KND93998.1 - 0.0021 17.8 0.0 0.0034 17.2 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KND93998.1 - 0.0047 16.3 0.1 0.0095 15.3 0.0 1.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KND93998.1 - 0.013 15.8 0.2 0.035 14.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KND93998.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KND93998.1 - 0.015 14.8 0.1 0.03 13.8 0.0 1.5 2 0 0 2 2 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KND93998.1 - 0.017 15.7 0.0 0.056 13.9 0.0 1.9 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 KND93998.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 KND93998.1 - 0.022 14.7 0.0 0.3 11.0 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 KND93998.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KND93998.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 KND93998.1 - 0.035 14.0 0.0 0.078 12.8 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND93998.1 - 0.064 13.2 0.1 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KND93998.1 - 0.067 12.8 0.1 0.2 11.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KND93998.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KND93998.1 - 0.094 12.4 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 KND93998.1 - 0.098 12.6 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KND93998.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 KND93998.1 - 0.15 11.6 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.25 KND93999.1 - 3.7e-16 59.3 0.0 3.6e-14 52.8 0.0 2.5 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND93999.1 - 0.015 14.6 0.0 0.059 12.6 0.0 1.9 2 1 1 3 3 3 0 Protein tyrosine kinase adh_short PF00106.25 KND94000.1 - 9.4e-24 83.9 0.1 1.2e-23 83.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND94000.1 - 1.3e-13 51.1 0.4 1.9e-09 37.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND94000.1 - 4.6e-06 26.7 0.0 6.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KND94000.1 - 5.5e-06 26.4 0.1 7.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND94000.1 - 0.0023 17.5 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KND94000.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family FMN_bind_2 PF04299.12 KND94001.1 - 3e-58 196.3 0.0 3.5e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Arc_PepC_II PF06847.11 KND94001.1 - 0.11 13.1 0.0 5.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II NmrA PF05368.13 KND94002.1 - 9.3e-19 67.9 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND94002.1 - 7.1e-14 52.1 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND94002.1 - 0.0088 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APOBEC_C PF05240.14 KND94002.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Cnl2_NKP2 PF09447.10 KND94003.1 - 9.2e-24 83.4 0.2 1.7e-23 82.6 0.2 1.4 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Citrate_synt PF00285.21 KND94004.1 - 2.2e-20 73.0 0.0 2.6e-17 62.9 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 KND94004.1 - 1e-18 67.8 0.1 3.1e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KND94004.1 - 8.9e-15 54.8 0.1 1.6e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KND94004.1 - 4e-05 23.4 0.0 0.00055 19.7 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.20 KND94005.1 - 8.4e-16 57.6 0.1 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_bind PF16114.5 KND94006.1 - 3.5e-87 290.5 0.0 4.9e-87 290.0 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KND94006.1 - 4.8e-07 29.6 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KND94006.1 - 0.0017 16.5 0.0 0.0026 16.0 0.0 1.2 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Guanylate_kin PF00625.21 KND94007.1 - 3.6e-62 209.3 0.0 4.3e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 KND94007.1 - 0.00075 19.7 0.5 0.021 15.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KND94007.1 - 0.0022 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 KND94007.1 - 0.0028 18.1 0.0 0.0056 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KND94007.1 - 0.0033 17.7 0.1 0.15 12.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND94007.1 - 0.0061 17.1 0.5 0.045 14.3 0.5 2.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KND94007.1 - 0.0079 16.3 0.0 0.036 14.2 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KND94007.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KND94007.1 - 0.053 13.4 0.3 2.5 7.9 0.0 2.4 2 1 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 KND94007.1 - 0.066 13.7 0.0 0.59 10.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SSE PF00437.20 KND94007.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Nop PF01798.18 KND94008.1 - 2.6e-80 269.2 0.2 2.6e-80 269.2 0.2 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KND94008.1 - 3.6e-19 68.9 2.0 3.6e-19 68.9 2.0 2.8 4 0 0 4 4 4 1 NOP5NT (NUC127) domain PBP1_TM PF14812.6 KND94008.1 - 0.72 10.3 23.4 0.33 11.4 7.7 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal vATP-synt_AC39 PF01992.16 KND94009.1 - 1.1e-106 357.2 0.0 1.2e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SNRNP27 PF08648.12 KND94010.1 - 5.2e-06 26.4 0.1 8.3e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins KxDL PF10241.9 KND94011.1 - 5.9e-22 77.7 0.2 1.1e-21 76.8 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein Cir_N PF10197.9 KND94013.1 - 9.7e-07 28.9 2.9 9.7e-07 28.9 2.9 5.0 5 1 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR RasGEF PF00617.19 KND94015.1 - 3e-47 161.1 0.9 4.7e-47 160.5 0.9 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KND94015.1 - 7.7e-12 45.4 0.1 2.3e-11 43.9 0.1 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif AAA PF00004.29 KND94016.1 - 9.9e-49 165.1 0.0 2.4e-37 128.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND94016.1 - 1.7e-09 37.3 0.1 4.9e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KND94016.1 - 1.9e-09 37.9 0.0 6.9e-05 23.1 0.0 3.6 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND94016.1 - 8.9e-09 36.0 0.0 0.0035 17.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain ATPase_2 PF01637.18 KND94016.1 - 2.2e-07 31.0 0.1 0.15 12.0 0.0 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea TIP49 PF06068.13 KND94016.1 - 9.2e-07 28.4 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KND94016.1 - 3.1e-06 27.3 0.0 0.058 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KND94016.1 - 5.5e-06 26.6 0.0 9.2e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 KND94016.1 - 6.2e-06 25.9 0.4 0.00014 21.6 0.1 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 KND94016.1 - 7.6e-06 26.0 0.0 0.00099 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 KND94016.1 - 4e-05 24.0 0.0 0.067 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 KND94016.1 - 8.5e-05 22.4 0.1 0.069 12.9 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND94016.1 - 9.1e-05 22.7 0.0 0.36 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KND94016.1 - 9.9e-05 22.9 0.0 0.065 13.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KND94016.1 - 0.00043 20.1 0.0 0.0088 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KND94016.1 - 0.00053 19.4 1.1 0.007 15.8 0.2 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KND94016.1 - 0.00076 19.0 0.5 0.083 12.4 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KND94016.1 - 0.00079 19.2 0.1 0.51 10.0 0.0 2.7 3 0 0 3 3 2 1 IstB-like ATP binding protein TsaE PF02367.17 KND94016.1 - 0.0024 17.9 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KND94016.1 - 0.0036 17.5 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KND94016.1 - 0.0042 17.0 0.6 11 5.9 0.0 3.6 3 0 0 3 3 3 0 NACHT domain ATPase PF06745.13 KND94016.1 - 0.005 16.2 0.6 0.012 15.0 0.2 1.8 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 KND94016.1 - 0.0057 15.8 0.0 1.4 7.9 0.1 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 KND94016.1 - 0.021 14.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KND94016.1 - 0.022 14.3 0.7 2.1 7.9 0.0 2.8 2 2 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KND94016.1 - 0.035 13.3 0.2 1.5 7.9 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 KND94016.1 - 0.053 14.0 0.2 0.55 10.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 KND94016.1 - 0.092 12.2 0.1 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein IPT PF01745.16 KND94016.1 - 0.16 11.4 0.1 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase TniB PF05621.11 KND94016.1 - 0.2 11.0 0.1 9.2 5.6 0.0 3.0 2 1 0 3 3 3 0 Bacterial TniB protein Ribosomal_S15 PF00312.22 KND94017.1 - 1.6e-24 85.9 0.5 6.5e-24 83.9 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KND94018.1 - 1.8e-25 89.4 0.4 4.1e-14 52.3 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KND94018.1 - 2.8e-05 25.4 15.1 4.8e-05 24.6 15.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S5_C PF03719.15 KND94021.1 - 1.5e-20 72.4 0.2 1.3e-19 69.4 0.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KND94021.1 - 1e-16 60.7 0.2 2e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain OAD_gamma PF04277.13 KND94022.1 - 0.0005 20.6 0.0 0.00071 20.1 0.0 1.3 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Proton_antipo_N PF00662.20 KND94022.1 - 0.0095 16.0 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Nckap1 PF09735.9 KND94022.1 - 0.022 12.7 0.0 0.024 12.6 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein TMEM154 PF15102.6 KND94022.1 - 0.059 13.3 0.0 0.065 13.1 0.0 1.0 1 0 0 1 1 1 0 TMEM154 protein family RNA_pol_Rpc82 PF05645.13 KND94023.1 - 1.2e-48 166.2 0.1 2.6e-48 165.0 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KND94023.1 - 2.2e-12 46.9 1.0 1.7e-09 37.7 0.0 4.2 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KND94023.1 - 0.014 15.2 0.0 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 TFIIE alpha subunit RIIa PF02197.17 KND94023.1 - 0.025 14.3 0.2 0.074 12.7 0.2 1.7 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit APC_u15 PF16636.5 KND94023.1 - 0.063 13.7 1.0 0.18 12.3 1.0 1.8 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Mito_carr PF00153.27 KND94024.1 - 9.3e-20 70.4 0.1 2.3e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein Apolipoprotein PF01442.18 KND94024.1 - 0.0054 16.6 7.3 0.0054 16.6 7.3 9.6 4 2 4 10 10 10 3 Apolipoprotein A1/A4/E domain MIF4G PF02854.19 KND94024.1 - 0.0083 15.8 0.1 0.054 13.1 0.1 2.4 1 0 0 1 1 1 1 MIF4G domain Rbsn PF11464.8 KND94024.1 - 0.045 13.5 1.8 0.36 10.6 0.2 3.3 3 0 0 3 3 3 0 Rabenosyn Rab binding domain UBA_2 PF08587.11 KND94024.1 - 0.15 12.2 10.8 80 3.5 0.0 7.1 5 1 2 7 7 7 0 Ubiquitin associated domain (UBA) Fe_dep_repress PF01325.19 KND94024.1 - 0.15 12.3 0.6 0.7 10.1 0.3 2.4 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain LsmAD PF06741.13 KND94025.1 - 1.3e-26 92.9 0.5 1.3e-26 92.9 0.5 2.7 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.20 KND94026.1 - 1.3e-13 51.2 0.0 2.2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND94026.1 - 6.8e-13 49.0 0.0 1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Cas9_Topo PF17894.1 KND94026.1 - 0.15 12.1 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 WW PF00397.26 KND94027.1 - 8.4e-11 41.8 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 WW domain SPX PF03105.19 KND94027.1 - 0.046 13.7 6.9 0.052 13.5 6.9 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KND94027.1 - 0.19 10.9 11.9 0.24 10.5 11.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KND94027.1 - 0.4 9.5 7.9 0.53 9.1 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 KND94027.1 - 0.73 9.8 2.1 1 9.4 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 KND94027.1 - 0.86 8.1 3.9 1.1 7.8 3.9 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 KND94027.1 - 1.1 9.2 13.7 0.089 12.8 9.4 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM76 PF16046.5 KND94027.1 - 3.3 7.0 7.5 4.7 6.5 7.5 1.1 1 0 0 1 1 1 0 FAM76 protein Glyco_hydro_61 PF03443.14 KND94028.1 - 0.012 15.5 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 IMUP PF15761.5 KND94028.1 - 3.5 8.4 11.2 7.6 7.3 11.2 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein AT_hook PF02178.19 KND94029.1 - 0.13 12.2 23.3 0.53 10.3 5.9 3.2 2 0 0 2 2 2 0 AT hook motif Meth_synt_2 PF01717.18 KND94030.1 - 1.9e-152 507.2 0.0 4.8e-148 492.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KND94030.1 - 3.5e-101 338.8 1.7 3.3e-92 309.4 0.1 4.4 4 1 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KND94030.1 - 7.6e-05 22.0 0.0 0.0052 16.0 0.0 2.6 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) Bac_small_YrzI PF09501.10 KND94030.1 - 0.12 12.5 4.1 0.37 10.9 4.1 1.8 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) MFS_1 PF07690.16 KND94032.1 - 1.9e-36 125.8 42.2 1.9e-36 125.8 42.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94032.1 - 4.2e-13 49.0 6.6 4.2e-13 49.0 6.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.20 KND94032.1 - 0.63 9.7 13.0 0.14 11.9 3.4 2.8 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Ost4 PF10215.9 KND94033.1 - 1.4e-16 60.0 1.6 1.5e-16 59.9 1.6 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase DFRP_C PF16543.5 KND94034.1 - 2e-26 92.3 6.4 2e-26 92.3 6.4 3.5 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 KND94034.1 - 3.1e-06 26.9 1.0 3.1e-06 26.9 1.0 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KND94034.1 - 2.8e-05 24.8 4.6 2.8e-05 24.8 4.6 3.6 2 2 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 KND94034.1 - 4.9e-05 23.0 7.6 0.0015 18.3 1.8 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KND94034.1 - 0.00041 20.3 5.6 0.00041 20.3 5.6 2.9 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_2 PF14608.6 KND94034.1 - 0.0012 19.2 10.5 0.034 14.6 4.2 2.6 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KND94034.1 - 0.006 16.8 0.1 0.3 11.3 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger containing family Mito_carr PF00153.27 KND94035.1 - 1.4e-37 127.5 8.7 4.5e-14 52.1 0.4 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Thr_synth_N PF14821.6 KND94036.1 - 1.1e-28 99.3 0.0 2.9e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KND94036.1 - 3.3e-18 66.1 0.0 2.3e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CS PF04969.16 KND94037.1 - 1e-07 32.8 0.0 1.7e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4202 PF13875.6 KND94037.1 - 0.014 15.3 0.6 0.021 14.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Cwf_Cwc_15 PF04889.12 KND94037.1 - 0.025 14.3 0.7 0.035 13.8 0.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRM_1 PF00076.22 KND94038.1 - 3.2e-17 62.1 0.0 5.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KND94038.1 - 3.2e-05 24.4 3.0 3.2e-05 24.4 3.0 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KND94038.1 - 0.0088 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 KND94038.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif WYL_2 PF10902.8 KND94038.1 - 0.087 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold DUF2470 PF10615.9 KND94039.1 - 2.1e-20 73.1 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KND94039.1 - 0.057 13.7 0.8 0.097 13.0 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Helicase_C PF00271.31 KND94040.1 - 1.8e-17 63.7 0.0 2.7e-15 56.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 KND94040.1 - 1.1e-14 54.6 0.0 2.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KND94040.1 - 1.6e-11 44.8 2.3 4.1e-11 43.4 2.3 1.7 1 0 0 1 1 1 1 RecQ zinc-binding SOG2 PF10428.9 KND94041.1 - 1.9e-77 261.6 2.4 9.9e-53 180.1 0.6 3.2 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_8 PF13855.6 KND94041.1 - 1.2e-15 57.0 5.1 5e-08 32.6 0.3 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KND94041.1 - 8.1e-13 48.3 7.1 4.3e-05 23.8 0.2 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KND94041.1 - 0.00023 20.9 4.0 0.51 10.5 0.0 4.5 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 KND94041.1 - 0.00097 19.4 5.5 5.5 7.9 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat DUF2408 PF10303.9 KND94041.1 - 0.002 18.7 0.1 0.0074 16.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) GCN5L1 PF06320.13 KND94042.1 - 6.5e-14 52.0 0.2 9.9e-14 51.5 0.2 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) TFIIA PF03153.13 KND94042.1 - 0.0011 19.0 2.3 0.0017 18.4 2.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 KND94042.1 - 0.038 12.7 2.7 0.041 12.6 2.7 1.1 1 0 0 1 1 1 0 Hamartin protein CDC45 PF02724.14 KND94042.1 - 0.84 7.9 4.9 1 7.5 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 KND94042.1 - 1.8 7.9 11.1 2.6 7.3 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 KND94042.1 - 3 7.7 8.4 3.5 7.4 6.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 KND94042.1 - 4.9 6.5 11.0 6.2 6.2 11.0 1.3 1 0 0 1 1 1 0 SDA1 ZapB PF06005.12 KND94043.1 - 0.00023 21.6 8.3 0.054 13.9 3.3 3.0 2 1 1 3 3 3 2 Cell division protein ZapB KASH_CCD PF14662.6 KND94043.1 - 0.00038 20.3 10.4 0.033 14.0 4.8 2.4 1 1 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 KND94043.1 - 0.00045 20.8 7.8 0.0021 18.7 2.6 2.5 1 1 2 3 3 3 1 Initiation control protein YabA TSC22 PF01166.18 KND94043.1 - 0.00074 19.8 9.0 0.026 14.8 3.5 3.7 4 0 0 4 4 4 1 TSC-22/dip/bun family Filament PF00038.21 KND94043.1 - 0.00088 19.0 6.4 0.015 14.9 6.4 2.1 1 1 0 1 1 1 1 Intermediate filament protein Fungal_TACC PF12709.7 KND94043.1 - 0.0013 19.1 6.6 0.75 10.3 0.1 2.7 2 1 0 2 2 2 2 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_1 PF00170.21 KND94043.1 - 0.0017 18.4 17.9 0.086 12.9 6.6 4.1 3 2 1 4 4 4 2 bZIP transcription factor Shugoshin_N PF07558.11 KND94043.1 - 0.0018 18.1 2.1 0.0018 18.1 2.1 3.4 4 0 0 4 4 4 1 Shugoshin N-terminal coiled-coil region KxDL PF10241.9 KND94043.1 - 0.0023 18.2 0.9 0.0051 17.0 0.3 1.8 2 0 0 2 2 1 1 Uncharacterized conserved protein HAP1_N PF04849.13 KND94043.1 - 0.0024 17.1 11.9 0.022 14.0 11.9 2.4 1 1 0 1 1 1 1 HAP1 N-terminal conserved region HALZ PF02183.18 KND94043.1 - 0.0026 17.9 8.4 0.43 10.8 2.6 3.3 3 0 0 3 3 3 2 Homeobox associated leucine zipper DivIC PF04977.15 KND94043.1 - 0.0047 16.7 8.9 0.042 13.6 2.9 3.2 2 1 1 3 3 3 1 Septum formation initiator ADIP PF11559.8 KND94043.1 - 0.0065 16.6 9.1 1.8 8.7 0.1 2.6 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 KND94043.1 - 0.0092 15.8 3.1 5.8 6.9 0.3 3.3 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 KND94043.1 - 0.014 15.4 7.2 0.029 14.4 2.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 KND94043.1 - 0.016 15.6 4.5 0.82 10.1 2.7 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CC2-LZ PF16516.5 KND94043.1 - 0.018 15.4 8.4 0.04 14.3 1.9 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4795 PF16043.5 KND94043.1 - 0.019 14.6 4.4 0.077 12.6 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF2570 PF10828.8 KND94043.1 - 0.027 14.3 4.5 0.036 13.9 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Prominin PF05478.11 KND94043.1 - 0.03 12.3 1.0 0.041 11.8 1.0 1.3 1 0 0 1 1 1 0 Prominin Ax_dynein_light PF10211.9 KND94043.1 - 0.043 13.8 8.3 0.56 10.1 3.1 3.0 1 1 2 3 3 3 0 Axonemal dynein light chain ApoLp-III PF07464.11 KND94043.1 - 0.066 13.3 3.8 0.73 9.9 0.8 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Cnn_1N PF07989.11 KND94043.1 - 0.15 12.3 8.7 0.53 10.5 4.0 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 KND94043.1 - 0.18 12.3 12.5 0.093 13.3 4.6 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region Tho2 PF11262.8 KND94043.1 - 0.26 10.4 6.9 0.097 11.8 3.4 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF948 PF06103.11 KND94043.1 - 0.27 11.5 0.7 1.9 8.8 0.1 2.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-H PF05837.12 KND94043.1 - 0.29 11.5 8.5 1.6 9.2 4.1 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF1090 PF06476.12 KND94043.1 - 0.32 11.1 12.1 0.055 13.6 7.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) Leu_zip PF15294.6 KND94043.1 - 0.33 10.4 7.9 1 8.8 3.3 2.2 1 1 1 2 2 2 0 Leucine zipper MbeD_MobD PF04899.12 KND94043.1 - 0.39 10.9 0.2 0.39 10.9 0.2 3.0 1 1 2 3 3 3 0 MbeD/MobD like Spc7 PF08317.11 KND94043.1 - 0.43 9.4 8.5 0.7 8.7 3.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KND94043.1 - 0.52 10.4 3.8 1.4 8.9 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) K-box PF01486.17 KND94043.1 - 0.53 10.5 11.4 2.5 8.4 3.5 3.9 3 2 2 5 5 5 0 K-box region GAS PF13851.6 KND94043.1 - 0.58 9.5 9.6 0.84 8.9 4.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 KND94043.1 - 0.58 10.5 9.5 3.9 7.9 3.4 2.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3450 PF11932.8 KND94043.1 - 0.59 9.4 5.8 0.28 10.4 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) LPP PF04728.13 KND94043.1 - 0.83 10.1 7.9 14 6.1 0.2 4.0 2 1 2 4 4 4 0 Lipoprotein leucine-zipper Prefoldin PF02996.17 KND94043.1 - 2.1 8.3 5.8 27 4.7 3.1 3.0 1 1 2 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 KND94043.1 - 2.1 7.6 7.7 5.2 6.3 7.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIVA PF05103.13 KND94043.1 - 2.5 8.2 7.0 5.5 7.1 2.6 3.0 1 1 2 3 3 2 0 DivIVA protein PRKG1_interact PF15898.5 KND94043.1 - 2.7 9.0 11.2 5.2 8.0 7.5 2.9 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 KND94043.1 - 2.7 8.0 13.9 0.34 11.0 4.1 2.6 2 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein NRBF2 PF08961.10 KND94043.1 - 3.6 7.1 8.9 2.9 7.5 2.7 2.7 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 KND94043.1 - 3.7 7.6 11.0 42 4.2 11.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KND94043.1 - 6.3 7.2 9.6 39 4.7 4.4 2.9 2 1 0 2 2 2 0 Csm1 N-terminal domain RTA1 PF04479.13 KND94044.1 - 6.4e-06 25.9 4.4 1.1e-05 25.2 4.4 1.6 1 1 0 1 1 1 1 RTA1 like protein TMEM37 PF15108.6 KND94044.1 - 0.015 15.2 0.7 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF1304 PF06993.12 KND94045.1 - 1.8e-40 137.4 4.8 2e-40 137.2 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Fungal_trans PF04082.18 KND94046.1 - 1.8e-12 46.9 1.1 3e-12 46.1 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94046.1 - 3.3e-07 30.3 8.4 6.7e-07 29.3 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4516 PF14990.6 KND94046.1 - 0.29 10.9 1.5 0.61 9.9 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Smg4_UPF3 PF03467.15 KND94047.1 - 3e-47 160.9 0.0 3e-47 160.9 0.0 2.9 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 KND94047.1 - 6.1e-06 26.0 0.0 0.00031 20.5 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.9 KND94048.1 - 0.0023 18.1 7.7 0.0023 18.1 7.7 2.2 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 NACHT_N PF17100.5 KND94048.1 - 0.0034 17.3 1.6 0.0034 17.3 1.6 2.1 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Dynactin_p22 PF07426.11 KND94048.1 - 0.0056 16.6 3.9 0.33 10.8 0.4 2.4 1 1 1 2 2 2 2 Dynactin subunit p22 DUF572 PF04502.13 KND94048.1 - 0.019 14.6 12.9 0.024 14.3 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCC-bdg_PDZ PF10506.9 KND94048.1 - 0.057 13.4 1.7 0.19 11.8 0.2 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Spc7 PF08317.11 KND94048.1 - 5.3 5.8 19.8 0.18 10.6 7.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Asp-B-Hydro_N PF05279.11 KND94048.1 - 5.4 7.0 13.1 8.4 6.4 13.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HSP70 PF00012.20 KND94049.1 - 7.8e-16 57.4 0.1 1.2e-13 50.1 0.1 2.1 2 0 0 2 2 2 2 Hsp70 protein Peptidase_M22 PF00814.25 KND94049.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family BcrAD_BadFG PF01869.20 KND94049.1 - 0.089 12.3 3.0 0.59 9.6 0.0 2.7 2 2 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family MUG113 PF13455.6 KND94049.1 - 0.16 12.7 0.0 0.89 10.3 0.0 2.3 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 SR-25 PF10500.9 KND94051.1 - 3.1 7.4 8.1 4.9 6.7 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-F_leu_zip PF10473.9 KND94052.1 - 0.00036 20.6 5.1 0.00064 19.8 5.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SF-assemblin PF06705.11 KND94052.1 - 0.0054 16.1 1.1 0.0084 15.5 1.1 1.2 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF5082 PF16888.5 KND94052.1 - 0.013 15.8 1.4 0.019 15.2 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HAUS-augmin3 PF14932.6 KND94052.1 - 0.017 14.7 1.1 0.032 13.8 1.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 KND94052.1 - 0.052 13.8 5.0 0.095 12.9 5.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FTCD_C PF04961.12 KND94052.1 - 0.059 13.1 1.2 0.093 12.5 0.3 1.7 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF3450 PF11932.8 KND94052.1 - 0.084 12.2 2.5 0.15 11.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 KND94052.1 - 0.094 12.1 4.0 0.12 11.7 2.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 KND94052.1 - 0.18 11.4 5.2 0.36 10.4 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 KND94052.1 - 0.42 9.4 4.9 0.66 8.8 4.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 KND94052.1 - 0.77 8.8 3.4 0.54 9.3 1.8 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 KND94052.1 - 1.3 9.4 4.5 17 5.9 2.1 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper FUSC PF04632.12 KND94052.1 - 1.9 6.9 3.6 2.8 6.4 3.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 KND94052.1 - 7.2 7.1 9.3 2.1 8.9 0.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB Ribosomal_S7 PF00177.21 KND94053.1 - 3.2e-37 127.5 1.7 4e-37 127.1 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DOCK_N PF16172.5 KND94054.1 - 8.2e-120 400.2 0.0 1.2e-119 399.7 0.0 1.2 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KND94054.1 - 3.7e-33 115.0 0.0 7.8e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 KND94054.1 - 5.4e-06 25.9 0.0 1.4e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KND94054.1 - 0.00037 20.3 0.0 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KND94054.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain zf-CSL PF05207.13 KND94055.1 - 1.2e-23 82.6 0.8 1.5e-23 82.3 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KND94055.1 - 0.0013 18.8 0.4 0.002 18.2 0.4 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-RING_4 PF14570.6 KND94055.1 - 0.037 13.8 0.7 0.063 13.1 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Terminase_GpA PF05876.12 KND94055.1 - 0.14 10.7 0.2 0.16 10.5 0.2 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) VapB_antitoxin PF09957.9 KND94055.1 - 0.15 12.0 0.1 0.57 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Prok-RING_1 PF14446.6 KND94055.1 - 0.38 10.7 3.4 0.81 9.7 3.4 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 KND94057.1 - 2.8e-18 65.9 18.9 2.3e-11 43.7 3.3 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KND94057.1 - 0.03 14.2 1.7 0.03 14.2 1.7 3.6 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF5526 PF17664.1 KND94057.1 - 0.045 13.3 6.9 0.079 12.5 6.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5526) zf-ribbon_3 PF13248.6 KND94057.1 - 1.1 8.8 7.6 3.3 7.3 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain rRNA_processing PF08524.11 KND94057.1 - 1.6 8.8 7.5 2.6 8.1 7.5 1.2 1 0 0 1 1 1 0 rRNA processing DUF1179 PF06678.11 KND94057.1 - 2.7 8.0 5.9 0.27 11.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DZR PF12773.7 KND94057.1 - 7.8 6.6 15.1 0.98 9.5 1.6 3.4 3 0 0 3 3 3 0 Double zinc ribbon ABC_membrane_2 PF06472.15 KND94058.1 - 3.4e-101 338.2 1.3 5.4e-101 337.5 1.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KND94058.1 - 9.6e-17 61.8 0.0 2.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KND94058.1 - 0.00031 20.6 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KND94058.1 - 0.033 14.7 0.3 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 KND94058.1 - 0.1 12.0 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KND94058.1 - 0.11 11.8 0.0 0.76 9.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KND94058.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KND94058.1 - 0.55 10.6 3.0 1 9.7 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain Ribosomal_S25 PF03297.15 KND94059.1 - 8.2e-38 128.7 4.4 8.9e-38 128.6 4.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KND94059.1 - 0.036 13.9 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 MarR family Acetyltransf_1 PF00583.25 KND94060.1 - 0.0012 19.1 0.0 0.0049 17.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 KND94060.1 - 0.0044 17.7 0.1 0.23 12.2 0.0 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4191 PF13829.6 KND94061.1 - 0.0069 15.8 1.8 0.014 14.8 1.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) Occludin_ELL PF07303.13 KND94061.1 - 2.6 8.8 11.7 1.3 9.8 1.3 2.8 1 1 1 2 2 2 0 Occludin homology domain Cyt-b5 PF00173.28 KND94062.1 - 2.8e-11 43.4 0.0 4.4e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.29 KND94063.1 - 1.6e-16 60.9 0.0 2.8e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KND94063.1 - 3.6e-15 56.1 0.0 9e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KND94063.1 - 6.3e-12 45.6 0.0 2.3e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KND94063.1 - 2.5e-08 34.1 0.0 4.8e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KND94063.1 - 6.3e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KND94063.1 - 8e-07 29.3 0.0 3e-06 27.5 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 KND94063.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND94063.1 - 4.6e-06 27.1 0.0 2.1e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 KND94063.1 - 5.5e-06 26.4 0.2 3.8e-05 23.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND94063.1 - 3e-05 23.8 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KND94063.1 - 4.9e-05 23.3 0.2 0.00021 21.3 0.1 2.1 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 KND94063.1 - 5e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 KND94063.1 - 7.2e-05 22.8 0.0 0.00043 20.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KND94063.1 - 8.6e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KND94063.1 - 0.00014 21.8 0.0 0.002 18.0 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND94063.1 - 0.00021 21.1 0.0 0.0008 19.2 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KND94063.1 - 0.00042 20.7 0.1 0.0018 18.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KND94063.1 - 0.00069 19.7 0.0 0.033 14.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KND94063.1 - 0.0051 16.5 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.16 KND94063.1 - 0.0056 16.2 0.9 1.3 8.4 0.0 2.6 2 1 1 3 3 3 1 PhoH-like protein AAA_18 PF13238.6 KND94063.1 - 0.0087 16.6 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KND94063.1 - 0.0092 15.8 0.1 0.049 13.4 0.2 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase TniB PF05621.11 KND94063.1 - 0.01 15.3 0.0 0.085 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 KND94063.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KND94063.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 KND94063.1 - 0.021 14.2 0.1 0.17 11.3 0.1 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KND94063.1 - 0.03 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KND94063.1 - 0.035 13.7 0.1 0.22 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 KND94063.1 - 0.037 13.9 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KND94063.1 - 0.039 14.3 0.0 0.09 13.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 KND94063.1 - 0.081 12.6 0.0 0.68 9.6 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein BTB_2 PF02214.22 KND94064.1 - 2.7e-06 27.6 0.1 0.001 19.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Mito_carr PF00153.27 KND94065.1 - 3.2e-65 216.1 5.2 7.7e-24 83.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KND94065.1 - 0.055 13.2 1.3 0.21 11.4 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) RhlB PF12300.8 KND94067.1 - 0.83 9.8 7.4 1.5 8.9 7.4 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB CENP-X PF09415.10 KND94068.1 - 2.6e-22 78.9 0.2 2.6e-22 78.9 0.2 1.7 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Carbpep_Y_N PF05388.11 KND94069.1 - 0.0073 16.8 4.0 0.063 13.8 0.1 2.5 2 1 1 3 3 3 2 Carboxypeptidase Y pro-peptide Peptidase_S10 PF00450.22 KND94069.1 - 0.052 13.0 0.0 0.06 12.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Peptidase_S10 PF00450.22 KND94070.1 - 1.5e-93 314.5 0.0 1.7e-93 314.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pro_isomerase PF00160.21 KND94071.1 - 1.4e-40 139.2 0.0 1.9e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 KND94072.1 - 1.5e-15 57.8 0.1 2.2e-14 54.1 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 KND94073.1 - 2.6e-43 148.1 0.0 5.5e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 KND94073.1 - 0.0018 18.7 0.7 0.0018 18.7 0.7 4.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) HSF_DNA-bind PF00447.17 KND94074.1 - 5.6e-28 97.4 0.7 1.2e-27 96.3 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 KND94074.1 - 0.15 12.5 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Ets-domain zf-ZPR1 PF03367.13 KND94075.1 - 4e-112 371.3 0.0 3.1e-57 192.9 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 KND94075.1 - 0.13 12.3 4.0 2.1 8.4 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2491 PF10679.9 KND94075.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF866 PF05907.13 KND94076.1 - 2.3e-56 190.0 0.1 2.3e-41 141.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) tRNA_int_end_N2 PF12928.7 KND94077.1 - 3.5e-24 84.8 0.2 6.8e-24 83.8 0.2 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KND94077.1 - 0.0054 16.4 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Aldedh PF00171.22 KND94079.1 - 3.4e-182 606.1 0.9 3.8e-182 605.9 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RTP1_C1 PF10363.9 KND94080.1 - 3.4e-24 85.2 0.3 2.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KND94080.1 - 1.2e-13 50.4 1.3 2.7e-13 49.3 1.3 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Adaptin_N PF01602.20 KND94080.1 - 0.00091 17.9 0.3 0.27 9.7 0.0 2.6 2 0 0 2 2 2 2 Adaptin N terminal region HTH_9 PF08221.11 KND94080.1 - 0.021 14.9 0.2 4.3 7.5 0.0 3.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain CENP-Q PF13094.6 KND94082.1 - 2.4e-48 164.5 6.1 2.4e-48 164.5 6.1 2.4 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit CDC45 PF02724.14 KND94082.1 - 2.7 6.2 5.3 4.9 5.3 5.3 1.6 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.10 KND94082.1 - 7.3 5.9 25.0 61 2.8 22.9 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MRG PF05712.13 KND94084.1 - 1.9e-59 200.3 0.2 2.8e-59 199.8 0.2 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KND94084.1 - 2.4e-07 30.6 0.3 4.8e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_hydro_72 PF03198.14 KND94085.1 - 3.8e-109 364.7 0.1 4.7e-109 364.4 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KND94085.1 - 0.016 14.7 0.3 0.089 12.2 0.3 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RNase_H PF00075.24 KND94086.1 - 6.2e-37 127.0 0.0 1.1e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KND94086.1 - 3.6e-33 113.6 11.4 5.5e-18 65.0 1.7 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin dCMP_cyt_deam_1 PF00383.23 KND94087.1 - 3e-08 33.5 0.0 6.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KND94087.1 - 0.0021 17.8 0.1 0.0048 16.7 0.1 1.5 1 0 0 1 1 1 1 MafB19-like deaminase 6PF2K PF01591.18 KND94088.1 - 1.9e-65 220.3 0.0 2.6e-45 154.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KND94088.1 - 1.1e-29 103.5 0.0 9.4e-24 84.2 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) CARD PF00619.21 KND94088.1 - 0.0029 17.6 0.1 0.0088 16.1 0.1 1.8 1 1 0 1 1 1 1 Caspase recruitment domain AAA_33 PF13671.6 KND94088.1 - 0.0053 16.9 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 KND94088.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Lipase_GDSL_3 PF14606.6 KND94088.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 KND94089.1 - 1.1e-32 111.5 7.4 7e-06 26.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.14 KND94089.1 - 1.6e-30 105.2 15.6 3.8e-30 104.0 15.6 1.6 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 KND94089.1 - 4.6e-09 36.4 0.5 0.081 13.2 0.1 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND94089.1 - 1e-05 24.7 0.1 0.06 12.3 0.0 3.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KND94089.1 - 0.0024 16.5 0.4 0.42 9.1 0.1 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain RNA_pol_A_bac PF01000.26 KND94090.1 - 1.6e-32 112.2 0.0 2.4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KND94090.1 - 1.4e-15 56.5 0.0 1.8e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calycin_like PF13944.6 KND94090.1 - 0.021 15.1 0.1 0.042 14.2 0.1 1.4 1 0 0 1 1 1 0 Calycin-like beta-barrel domain PriA_CRR PF18319.1 KND94090.1 - 0.079 13.0 1.3 0.15 12.1 1.3 1.4 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain Mito_carr PF00153.27 KND94091.1 - 2e-49 165.4 1.1 1.6e-16 60.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 KND94092.1 - 9.6e-47 159.5 0.6 2.8e-23 82.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KND94092.1 - 1e-25 89.9 0.0 5.2e-25 87.7 0.0 2.2 2 1 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.12 KND94093.1 - 2.7e-51 174.0 0.0 3.3e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Neugrin PF06413.11 KND94094.1 - 1.9e-11 44.4 0.4 1.9e-11 44.4 0.4 2.2 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 KND94094.1 - 9.1e-07 29.2 5.2 1.7e-06 28.3 5.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 KND94094.1 - 0.088 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain adh_short PF00106.25 KND94095.1 - 7.2e-39 133.3 0.1 1e-38 132.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND94095.1 - 3.6e-33 115.1 0.0 5.1e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND94095.1 - 3.8e-11 43.2 3.8 3.9e-10 39.9 3.8 2.1 1 1 0 1 1 1 1 KR domain CENP-N PF05238.13 KND94096.1 - 1.5e-134 449.4 0.0 1.7e-134 449.2 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like CDPS PF16715.5 KND94096.1 - 0.044 13.4 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase bZIP_2 PF07716.15 KND94097.1 - 2.4e-12 46.7 9.8 4.3e-12 45.9 9.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper XhlA PF10779.9 KND94097.1 - 0.025 14.8 3.2 0.056 13.6 3.2 1.6 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_1 PF00170.21 KND94097.1 - 0.033 14.3 12.3 0.066 13.3 11.3 1.9 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 KND94097.1 - 0.43 10.9 2.2 0.34 11.3 0.3 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 KND94097.1 - 1.4 9.6 4.8 1.2 9.9 2.8 2.0 2 1 1 3 3 3 0 Initiation control protein YabA Ribonuc_red_lgC PF02867.15 KND94098.1 - 2e-192 640.4 0.0 3.2e-192 639.7 0.0 1.3 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KND94098.1 - 6.9e-25 86.9 0.0 1.8e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KND94098.1 - 1.1e-15 57.9 0.0 2.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain TatD_DNase PF01026.21 KND94099.1 - 6.7e-50 169.8 0.0 1.3e-49 168.9 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Pirin PF02678.16 KND94100.1 - 2.4e-29 101.5 0.0 1e-28 99.4 0.0 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 KND94100.1 - 7.6e-25 87.3 0.0 3.4e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KND94100.1 - 1.8e-07 30.7 2.8 1.7e-05 24.4 1.0 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KND94100.1 - 0.016 14.9 0.2 0.24 11.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CFEM PF05730.11 KND94101.1 - 8.8e-08 32.1 6.4 1.6e-07 31.3 6.4 1.5 1 0 0 1 1 1 1 CFEM domain DENN PF02141.21 KND94102.1 - 7.8e-40 136.8 0.1 1.4e-39 136.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KND94102.1 - 6.7e-07 30.0 0.1 3.2e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 KND94102.1 - 0.79 10.3 11.9 0.048 14.2 5.7 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cnn_1N PF07989.11 KND94102.1 - 7.3 6.8 16.3 1.5 9.0 4.9 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 PCRF PF03462.18 KND94102.1 - 7.4 6.4 12.6 1.1 9.1 5.3 2.6 1 1 2 3 3 3 0 PCRF domain Perilipin PF03036.16 KND94103.1 - 0.022 13.8 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Perilipin family EF-hand_4 PF12763.7 KND94104.1 - 1.8e-34 117.8 0.0 1.9e-12 47.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 KND94104.1 - 3e-07 30.2 0.1 6.7e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 KND94104.1 - 7.6e-05 23.1 0.0 0.033 14.6 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair DUF3584 PF12128.8 KND94104.1 - 0.0034 15.0 21.5 0.005 14.5 21.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) EF-hand_6 PF13405.6 KND94104.1 - 0.038 13.9 0.0 29 5.0 0.0 3.7 3 0 0 3 3 3 0 EF-hand domain Golgin_A5 PF09787.9 KND94104.1 - 0.044 13.3 22.1 0.084 12.3 22.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 KND94104.1 - 0.057 12.3 25.6 0.43 9.4 11.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KND94104.1 - 0.11 12.6 28.8 0.85 9.7 15.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KND94104.1 - 0.14 11.5 26.2 0.28 10.5 5.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KND94104.1 - 0.24 11.4 24.7 0.24 11.4 5.2 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KND94104.1 - 0.34 11.1 23.2 1.3 9.3 4.4 3.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KND94104.1 - 0.41 10.7 31.6 0.19 11.8 4.9 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 KND94104.1 - 0.56 10.4 32.6 2.7 8.2 23.5 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 KND94104.1 - 0.81 7.6 10.0 1.2 7.0 10.0 1.2 1 0 0 1 1 1 0 Prominin YkyA PF10368.9 KND94104.1 - 0.82 9.3 20.9 2.2 7.9 4.5 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Fez1 PF06818.15 KND94104.1 - 1.1 9.7 24.7 46 4.4 24.6 2.2 1 1 0 1 1 1 0 Fez1 FUSC PF04632.12 KND94104.1 - 1.4 7.4 7.5 2.1 6.8 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 KND94104.1 - 1.7 8.8 20.1 0.19 11.9 11.9 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 KND94104.1 - 2.1 8.7 21.2 11 6.5 15.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 KND94104.1 - 2.4 9.1 25.5 0.11 13.4 8.7 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 KND94104.1 - 2.9 7.9 15.5 1.3 9.0 7.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KND94104.1 - 3.9 8.0 28.6 1.4e+02 3.0 23.9 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 KND94104.1 - 4.3 6.1 17.2 0.5 9.1 1.1 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Pannexin_like PF12534.8 KND94104.1 - 6 5.8 4.7 11 5.1 4.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF724 PF05266.14 KND94104.1 - 6.4 6.6 18.8 1.8 8.4 7.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF724) Exonuc_VII_L PF02601.15 KND94104.1 - 6.4 6.3 15.2 11 5.5 15.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KND94104.1 - 7.4 5.8 29.9 1 8.6 7.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Occludin_ELL PF07303.13 KND94104.1 - 7.5 7.3 11.4 4.7 8.0 2.2 2.6 1 1 1 2 2 2 0 Occludin homology domain Tup_N PF08581.10 KND94104.1 - 9.1 6.7 16.5 2.2 8.6 7.4 2.7 1 1 1 2 2 2 0 Tup N-terminal SOGA PF11365.8 KND94104.1 - 9.4 7.4 18.6 6.9 7.9 0.7 2.8 1 1 1 3 3 2 0 Protein SOGA zf-HIT PF04438.16 KND94105.1 - 5.5e-08 32.6 9.6 1.1e-07 31.6 9.6 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KND94105.1 - 0.43 10.7 9.1 0.81 9.8 9.1 1.4 1 0 0 1 1 1 0 MYND finger VTC PF09359.10 KND94106.1 - 2.7e-87 292.7 0.2 4.4e-87 292.0 0.2 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KND94106.1 - 9.7e-11 42.0 3.2 9.7e-11 42.0 3.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 KND94106.1 - 3.6e-07 30.5 17.7 0.00058 19.9 0.1 3.9 3 1 0 5 5 5 2 SPX domain T3SSipB PF16535.5 KND94106.1 - 0.024 15.1 0.6 0.024 15.1 0.6 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB AXIN1_TNKS_BD PF16646.5 KND94106.1 - 0.06 14.3 2.8 5 8.1 0.7 2.6 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain GATase_2 PF00310.21 KND94107.1 - 7e-182 604.8 0.0 1e-181 604.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KND94107.1 - 2.5e-147 490.9 0.0 5.7e-147 489.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KND94107.1 - 5.3e-111 370.6 0.0 3.2e-109 364.8 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KND94107.1 - 1.3e-85 285.8 1.6 2e-85 285.2 1.6 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 KND94107.1 - 1.6e-22 80.1 0.0 1.4e-21 77.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 KND94107.1 - 2.5e-21 75.6 0.1 4.7e-21 74.7 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 KND94107.1 - 4e-08 33.4 0.0 1.5e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KND94107.1 - 1.3e-07 32.1 0.0 0.00025 21.5 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND94107.1 - 7.9e-06 25.7 0.5 0.00085 19.0 0.2 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KND94107.1 - 3.6e-05 23.3 0.1 6.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 KND94107.1 - 8.2e-05 21.5 0.1 0.00016 20.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KND94107.1 - 0.0002 20.8 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND94107.1 - 0.00045 19.6 0.8 0.18 11.0 0.1 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KND94107.1 - 0.0055 15.8 0.0 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FMN_dh PF01070.18 KND94107.1 - 0.014 14.4 1.5 0.09 11.8 1.5 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase FAD_binding_3 PF01494.19 KND94107.1 - 0.032 13.5 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KND94107.1 - 0.039 13.2 0.0 0.13 11.5 0.0 1.8 1 0 0 1 1 1 0 Thi4 family GATase_6 PF13522.6 KND94107.1 - 0.058 13.6 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF1048 PF06304.11 KND94107.1 - 0.079 13.4 0.2 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) NAD_Gly3P_dh_N PF01210.23 KND94107.1 - 0.087 12.8 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 KND94107.1 - 0.11 11.6 0.3 0.86 8.6 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FMO-like PF00743.19 KND94107.1 - 0.12 10.8 0.1 2.6 6.4 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KND94107.1 - 0.13 11.3 1.1 0.24 10.4 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KND94107.1 - 0.17 11.5 0.1 0.47 10.1 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KND94107.1 - 0.18 12.2 0.5 41 4.7 0.0 3.0 3 0 0 3 3 2 0 Putative NAD(P)-binding FGGY_C PF02782.16 KND94108.1 - 5.1e-49 166.7 0.9 7.2e-49 166.2 0.1 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KND94108.1 - 5e-25 88.5 0.4 6.1e-24 84.9 0.0 2.6 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KND94108.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Hexokinase BcrAD_BadFG PF01869.20 KND94108.1 - 0.16 11.4 0.2 0.75 9.2 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3425 PF11905.8 KND94110.1 - 2.6e-23 82.3 0.2 3.9e-23 81.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KND94110.1 - 0.0058 16.7 6.2 0.012 15.7 6.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Nic96 PF04097.14 KND94111.1 - 2.9e-223 742.8 0.0 3.9e-223 742.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 KND94111.1 - 2.2e-11 44.5 63.7 3.3e-11 43.9 39.5 4.7 3 1 2 5 5 5 2 Nucleoporin FG repeat region DUF1129 PF06570.11 KND94111.1 - 3.9 6.9 4.9 34 3.9 4.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Cation_ATPase_N PF00690.26 KND94112.1 - 4.3e-10 39.1 0.8 2.8e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 KND94113.1 - 2.9e-49 167.0 8.3 4.1e-49 166.5 5.8 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KND94113.1 - 3.2e-16 60.3 0.0 9.5e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KND94113.1 - 0.002 17.9 0.0 0.0074 16.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase O-antigen_lig PF13425.6 KND94113.1 - 0.029 13.2 4.4 0.21 10.4 5.1 1.9 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Citrate_synt PF00285.21 KND94114.1 - 9.6e-99 330.9 0.0 1.2e-98 330.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 KND94114.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 KND94115.1 - 3.5e-09 37.3 0.0 6.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 KND94115.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Casc1_N PF15927.5 KND94116.1 - 0.011 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus TPR_17 PF13431.6 KND94116.1 - 0.015 15.6 0.2 0.28 11.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L27e PF01777.18 KND94117.1 - 3.4e-35 120.2 1.7 3.4e-35 120.2 1.7 1.6 2 0 0 2 2 2 1 Ribosomal L27e protein family KOW PF00467.29 KND94117.1 - 0.025 14.5 0.9 0.025 14.5 0.9 1.9 2 0 0 2 2 2 0 KOW motif PuR_N PF09182.10 KND94117.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal DUF469 PF04320.14 KND94117.1 - 0.12 13.3 0.0 1.8 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein with unknown function (DUF469) DUF3666 PF12408.8 KND94117.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase RabGAP-TBC PF00566.18 KND94120.1 - 9.5e-35 120.2 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.19 KND94121.1 - 9.6e-33 112.6 0.8 2.1e-32 111.5 0.8 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KND94121.1 - 5.3e-22 78.2 0.1 7.5e-13 48.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND94121.1 - 1.1e-12 48.2 0.0 3.1e-07 30.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KND94121.1 - 6.1e-10 39.1 0.0 0.0003 21.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KND94121.1 - 6.7e-08 32.7 0.0 4e-05 23.8 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND94121.1 - 5.8e-07 29.3 0.0 0.52 11.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat TPT PF03151.16 KND94122.1 - 1.1e-23 84.0 26.5 1.1e-23 84.0 26.5 1.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KND94122.1 - 0.00049 20.3 41.4 0.0086 16.2 14.8 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 KND94122.1 - 0.0023 17.2 27.8 0.0056 15.9 27.8 1.6 1 1 0 1 1 1 1 UAA transporter family Amino_oxidase PF01593.24 KND94123.1 - 1.3e-07 31.3 0.0 2.6e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND94123.1 - 1.3e-06 28.5 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND94123.1 - 0.045 13.0 0.1 2 7.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.11 KND94123.1 - 0.049 13.5 0.3 0.13 12.2 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) PRIMA1 PF16101.5 KND94124.1 - 6.6 6.8 6.2 0.85 9.7 2.1 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HATPase_c PF02518.26 KND94125.1 - 9.8e-32 109.8 0.0 2.7e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KND94125.1 - 7.8e-21 74.3 0.1 1.8e-20 73.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KND94125.1 - 3.7e-18 65.3 0.5 1.5e-17 63.3 0.5 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KND94125.1 - 1.8e-12 47.7 0.0 9.6e-12 45.4 0.0 2.3 2 0 0 2 2 1 1 GAF domain AAA_16 PF13191.6 KND94125.1 - 4.5e-12 46.7 1.2 2.3e-11 44.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain GAF PF01590.26 KND94125.1 - 2.1e-07 31.6 0.0 1e-06 29.4 0.0 2.3 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KND94125.1 - 4.1e-06 26.3 0.0 7.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HATPase_c_3 PF13589.6 KND94125.1 - 0.0002 21.2 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_19 PF14559.6 KND94125.1 - 0.009 16.5 1.4 1.7 9.2 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NB-ARC PF00931.22 KND94125.1 - 0.012 14.8 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain GAF_3 PF13492.6 KND94125.1 - 0.023 15.0 0.0 0.085 13.2 0.0 2.0 1 0 0 1 1 1 0 GAF domain Alanine_zipper PF11839.8 KND94125.1 - 2.2 8.7 14.1 0.67 10.4 10.1 2.3 2 0 0 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein TPR_12 PF13424.6 KND94125.1 - 2.3 8.6 8.8 2 8.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KND94125.1 - 2.6 8.5 6.6 20 5.7 0.0 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KND94125.1 - 2.8 8.3 6.0 6.1 7.2 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND94125.1 - 6.3 6.8 5.6 2.7 8.0 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PUF PF00806.19 KND94126.1 - 1.9e-39 131.1 0.1 3.4e-06 26.4 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 KND94126.1 - 0.29 11.3 0.8 0.65 10.2 0.0 2.1 3 0 0 3 3 3 0 RasGEF domain MRP-S33 PF08293.11 KND94127.1 - 6.5e-27 93.6 0.0 7.4e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Amidoligase_2 PF12224.8 KND94128.1 - 0.00018 21.3 0.1 0.00036 20.3 0.1 1.5 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribonuclease_3 PF00636.26 KND94130.1 - 3.2e-14 53.4 0.1 1.1e-13 51.7 0.0 1.9 1 1 1 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KND94130.1 - 3.7e-07 30.4 0.0 6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KND94130.1 - 0.085 13.6 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif F-box PF00646.33 KND94131.1 - 0.0017 18.2 0.2 0.0039 17.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KND94131.1 - 0.0022 17.8 0.1 0.0049 16.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF2722 PF10846.8 KND94132.1 - 0.0014 17.7 16.2 0.0017 17.4 8.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) EPL1 PF10513.9 KND94132.1 - 0.037 14.4 10.9 0.37 11.2 0.2 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Maf1 PF09174.10 KND94132.1 - 0.052 13.7 1.3 3 8.0 0.4 2.2 2 0 0 2 2 2 0 Maf1 regulator Eapp_C PF10238.9 KND94132.1 - 0.083 13.0 3.8 0.35 10.9 0.6 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.8 KND94132.1 - 0.2 10.4 9.8 1.4 7.7 5.3 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.13 KND94132.1 - 0.62 10.7 28.2 2.8 8.6 0.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 KND94132.1 - 0.69 9.8 31.5 2.5 8.0 0.7 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rxt3 PF08642.10 KND94132.1 - 1.2 10.0 7.3 4.5 8.1 3.0 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CAP_N PF01213.19 KND94132.1 - 1.8 8.0 22.4 1.3 8.4 17.4 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4834 PF16118.5 KND94132.1 - 3 8.9 14.5 26 5.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 KND94132.1 - 4 7.8 6.8 15 5.9 2.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 KND94132.1 - 4.6 6.6 8.6 3.4 7.1 4.3 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF702 PF05142.12 KND94132.1 - 5.1 7.6 12.6 3.8 8.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF4770 PF15994.5 KND94132.1 - 6 7.1 11.4 4.9 7.4 6.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF775 PF05603.12 KND94132.1 - 6.5 6.2 8.5 0.44 10.0 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Molybdopterin PF00384.22 KND94133.1 - 9.3e-75 252.2 0.0 4.2e-73 246.8 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KND94133.1 - 1.7e-20 72.9 0.3 5.7e-20 71.2 0.3 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 KND94133.1 - 4.6e-19 68.8 0.0 1.5e-18 67.2 0.0 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 KND94133.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KND94133.1 - 1.1e-08 34.9 0.6 1.1e-08 34.9 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KND94133.1 - 0.055 13.2 0.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 KND94133.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 KND94133.1 - 0.12 12.3 1.1 3.5 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ACBP PF00887.19 KND94135.1 - 2.7e-24 85.2 0.0 6.2e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein BatD PF13584.6 KND94135.1 - 0.12 11.2 0.4 0.16 10.7 0.4 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 KND94135.1 - 3.9 7.7 9.5 0.63 10.3 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Fungal_trans PF04082.18 KND94136.1 - 7.8e-20 71.0 0.2 1.1e-19 70.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5557 PF17712.1 KND94136.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5557) Zn_clus PF00172.18 KND94136.1 - 0.056 13.6 6.0 0.14 12.3 6.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 KND94137.1 - 2.5e-17 63.1 0.0 1.1e-15 57.7 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KND94137.1 - 1.4e-10 40.8 1.6 2.9e-10 39.9 0.2 2.3 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KND94137.1 - 1.6e-06 27.9 0.1 4.5e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 KND94137.1 - 0.0018 18.3 1.2 0.11 12.5 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 KND94137.1 - 0.0025 17.4 1.2 0.0064 16.1 0.4 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 KND94137.1 - 0.028 13.1 0.2 0.13 11.0 0.2 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Amino_oxidase PF01593.24 KND94138.1 - 1.6e-21 77.2 0.1 1.8e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND94138.1 - 2.7e-09 37.1 0.1 5.4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND94138.1 - 7.2e-05 22.5 0.1 0.0057 16.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND94138.1 - 0.00046 19.5 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KND94138.1 - 0.0013 18.8 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 KND94138.1 - 0.0099 14.6 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KND94138.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KND94138.1 - 0.1 11.9 0.0 6.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CtaG_Cox11 PF04442.14 KND94139.1 - 7.4e-60 201.4 0.0 4.4e-59 198.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 NAD_binding_10 PF13460.6 KND94140.1 - 2.7e-26 92.6 0.0 7.5e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KND94140.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KND94140.1 - 0.026 14.0 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family LSM14 PF12701.7 KND94141.1 - 1.2e-29 102.2 0.1 2.4e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KND94141.1 - 8.6e-22 78.0 2.2 2.1e-21 76.7 2.2 1.7 1 0 0 1 1 1 1 FDF domain V-SNARE_C PF12352.8 KND94141.1 - 1.6e-18 66.7 2.4 3.8e-18 65.5 2.4 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 KND94141.1 - 2.7e-18 66.1 2.7 6.4e-18 64.9 2.7 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus FAM219A PF15260.6 KND94141.1 - 0.0079 16.6 0.7 0.031 14.7 0.7 2.0 1 0 0 1 1 1 1 Protein family FAM219A Sec20 PF03908.13 KND94141.1 - 0.014 15.3 0.3 0.03 14.2 0.3 1.5 1 0 0 1 1 1 0 Sec20 SET PF00856.28 KND94143.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.7 2 0 0 2 2 2 0 SET domain FTCD_N PF07837.12 KND94144.1 - 0.09 12.6 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase domain, N-terminal subdomain RNA_pol_Rpb2_6 PF00562.28 KND94146.1 - 2e-123 412.3 0.0 3.3e-123 411.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KND94146.1 - 2e-54 184.2 0.2 3.7e-54 183.3 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 KND94146.1 - 3.3e-33 114.0 0.6 7.2e-33 112.9 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 KND94146.1 - 4.7e-29 101.4 0.1 1.3e-28 99.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KND94146.1 - 2.1e-22 79.2 0.2 5.6e-22 77.8 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KND94146.1 - 1.7e-20 73.0 0.0 3.5e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KND94146.1 - 1.6e-10 41.4 0.5 5.5e-10 39.6 0.5 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNase_HII PF01351.18 KND94147.1 - 1.8e-45 155.2 0.0 4.1e-45 154.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII Adeno_VII PF03228.14 KND94147.1 - 0.12 13.0 0.7 0.33 11.6 0.2 2.0 2 0 0 2 2 2 0 Adenoviral core protein VII Mif2_N PF15624.6 KND94148.1 - 5.6e-35 121.0 1.5 5.6e-35 121.0 1.5 3.4 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KND94148.1 - 1.7e-33 114.7 0.1 2.7e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KND94148.1 - 5.3e-06 26.0 0.0 1.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KND94148.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF3128 PF11326.8 KND94149.1 - 1.6e-27 95.7 2.8 3e-27 94.8 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SR-25 PF10500.9 KND94149.1 - 1.1 8.8 9.3 2.1 7.9 9.3 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_pp85 PF04637.12 KND94149.1 - 5 5.4 7.6 6.9 5.0 7.6 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SOG2 PF10428.9 KND94149.1 - 5.5 6.1 11.1 7.5 5.6 11.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein HSP70 PF00012.20 KND94150.1 - 2.2e-247 822.1 8.2 4.7e-124 414.8 0.9 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KND94150.1 - 3.1e-15 55.8 0.0 1e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 MreB/Mbl protein Actin PF00022.19 KND94150.1 - 0.0044 15.7 0.0 0.31 9.6 0.0 2.4 1 1 0 1 1 1 1 Actin FGGY_C PF02782.16 KND94150.1 - 0.0099 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 KND94150.1 - 0.032 13.5 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 KND94150.1 - 0.052 14.0 1.0 13 6.2 0.1 3.3 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 KND94150.1 - 0.053 12.7 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 StbA protein MFS_1 PF07690.16 KND94152.1 - 9.1e-20 70.9 10.8 1.1e-19 70.5 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94152.1 - 1.5e-05 24.0 8.0 2e-05 23.7 8.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Carn_acyltransf PF00755.20 KND94153.1 - 1.7e-206 687.4 0.0 3.6e-206 686.3 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase FTR1 PF03239.14 KND94155.1 - 1.3e-80 270.8 9.1 1.6e-80 270.6 9.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Ferlin_C PF16165.5 KND94155.1 - 0.16 11.9 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ferlin C-terminus DUF2721 PF11026.8 KND94155.1 - 0.2 11.5 4.0 17 5.3 1.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4293 PF14126.6 KND94155.1 - 0.29 11.4 2.9 2.1 8.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) DUF3464 PF11947.8 KND94155.1 - 4.2 7.1 5.1 3.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Cu-oxidase_3 PF07732.15 KND94156.1 - 1.7e-45 153.9 3.8 2.1e-42 143.9 0.8 3.5 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND94156.1 - 1.7e-43 147.6 6.5 2.8e-39 134.0 0.1 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KND94156.1 - 1.6e-42 145.3 1.2 2.2e-37 128.6 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KND94156.1 - 0.00021 21.3 0.0 2.3 8.4 0.0 3.7 2 1 0 2 2 2 2 Cupredoxin-like domain C1q PF00386.21 KND94156.1 - 0.053 13.7 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 C1q domain OMPdecase PF00215.24 KND94157.1 - 2.7e-104 347.7 0.0 4e-104 347.1 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.18 KND94157.1 - 5.6e-10 38.7 0.0 8.7e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94157.1 - 3.1e-07 30.4 10.8 6.7e-07 29.3 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.8 KND94157.1 - 1.7 8.7 5.3 4 7.6 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) zf_CCCH_4 PF18345.1 KND94158.1 - 0.00014 21.8 5.6 0.0044 17.0 0.3 3.7 2 1 1 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 KND94158.1 - 0.002 18.0 0.8 0.002 18.0 0.8 3.2 3 1 1 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KND94158.1 - 0.0071 17.0 0.3 0.0071 17.0 0.3 2.5 1 1 1 2 2 2 1 Torus domain AAA_lid_7 PF17867.1 KND94158.1 - 0.1 12.8 1.4 0.24 11.6 1.4 1.6 1 0 0 1 1 1 0 Midasin AAA lid domain Atg14 PF10186.9 KND94158.1 - 0.21 10.6 3.9 0.33 10.0 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CCCH_3 PF15663.5 KND94158.1 - 2.6 8.3 5.8 0.55 10.5 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger containing family Dynactin PF12455.8 KND94159.1 - 4.1e-108 360.9 4.8 4.1e-108 360.9 4.8 3.4 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 KND94159.1 - 2e-22 79.0 0.4 3.6e-22 78.2 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF2353 PF09789.9 KND94159.1 - 0.00024 20.6 23.4 0.00024 20.6 23.4 4.6 3 1 1 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) TolA_bind_tri PF16331.5 KND94159.1 - 0.0075 16.3 1.5 0.0075 16.3 1.5 8.5 4 2 4 8 8 8 2 TolA binding protein trimerisation HMG_box PF00505.19 KND94160.1 - 5.1e-22 78.1 3.8 1e-21 77.1 3.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND94160.1 - 2.7e-07 31.1 2.1 7.2e-07 29.7 2.1 1.7 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-bind_2 PF08914.11 KND94160.1 - 0.053 13.7 0.8 0.12 12.6 0.8 1.5 1 0 0 1 1 1 0 Rap1 Myb domain CHDNT PF08073.12 KND94160.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain TIP49 PF06068.13 KND94161.1 - 8.6e-167 554.7 0.0 1.1e-166 554.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KND94161.1 - 2.9e-25 88.2 0.3 6.5e-25 87.0 0.3 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KND94161.1 - 2.2e-11 44.3 1.3 4.5e-07 30.3 0.1 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND94161.1 - 8.9e-09 35.3 0.0 2.6e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KND94161.1 - 0.00021 21.6 0.4 0.21 11.8 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KND94161.1 - 0.00042 20.7 0.5 0.12 12.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND94161.1 - 0.00066 20.1 0.1 0.0063 16.9 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KND94161.1 - 0.00069 19.9 0.1 0.0022 18.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND94161.1 - 0.005 16.8 0.1 0.14 12.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KND94161.1 - 0.0073 16.8 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KND94161.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 KND94161.1 - 0.021 14.1 0.2 0.062 12.6 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 KND94161.1 - 0.024 14.4 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KND94161.1 - 0.026 14.1 0.1 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KND94161.1 - 0.029 13.7 0.1 0.84 9.0 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KND94161.1 - 0.03 14.0 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 KND94161.1 - 0.055 12.7 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KND94161.1 - 0.078 12.5 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 KND94161.1 - 0.11 12.2 0.2 3 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2204 PF09970.9 KND94162.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) TraD PF06412.11 KND94162.1 - 0.04 13.7 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 Conjugal transfer protein TraD Coa1 PF08695.10 KND94165.1 - 1.1e-39 134.8 0.0 1.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ALMS_repeat PF18727.1 KND94165.1 - 0.11 12.4 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat CUE PF02845.16 KND94166.1 - 3.2e-12 45.9 0.0 5.6e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ank_4 PF13637.6 KND94167.1 - 1.2e-30 105.5 12.4 2e-09 37.8 0.0 6.0 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND94167.1 - 1.5e-26 92.8 2.2 2e-09 37.9 0.1 4.3 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) SPX PF03105.19 KND94167.1 - 7.7e-21 75.5 17.8 2.7e-09 37.4 1.5 3.3 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 KND94167.1 - 1.5e-17 63.4 9.0 0.00012 22.3 0.1 6.8 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND94167.1 - 1.7e-15 55.6 5.4 9.1e-05 22.6 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KND94167.1 - 1.4e-12 47.5 7.2 0.00088 19.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat GDPD PF03009.17 KND94167.1 - 7.2e-09 35.7 0.0 1.6e-07 31.3 0.0 2.8 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family EzrA PF06160.12 KND94167.1 - 0.079 11.1 6.0 0.14 10.3 6.0 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rrn6 PF10214.9 KND94169.1 - 1.9e-156 522.9 1.5 2.4e-156 522.6 1.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 KND94170.1 - 3.6e-25 88.0 0.5 8e-25 86.8 0.1 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 S6PP PF05116.13 KND94170.1 - 0.01 15.4 0.2 0.022 14.3 0.1 1.5 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase DUF4407 PF14362.6 KND94170.1 - 0.096 12.0 5.6 0.12 11.7 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRRM_C PF15230.6 KND94170.1 - 1.1 9.9 5.8 0.16 12.5 0.8 2.2 2 1 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Hom_end_hint PF05203.16 KND94170.1 - 1.1 9.1 4.4 2.4 8.1 4.4 1.6 1 0 0 1 1 1 0 Hom_end-associated Hint V_ATPase_I PF01496.19 KND94170.1 - 1.7 6.5 7.8 2.1 6.1 7.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L3 PF00297.22 KND94171.1 - 2.1e-16 59.9 4.3 8.4e-13 48.0 4.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 GN3L_Grn1 PF08701.11 KND94171.1 - 0.082 13.0 5.3 0.16 12.1 5.3 1.4 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase PITH PF06201.13 KND94172.1 - 2.8e-41 141.2 0.0 3.4e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain MOZART1 PF12554.8 KND94173.1 - 1.1e-23 82.7 0.6 1.3e-23 82.5 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.6 KND94174.1 - 4e-25 87.6 0.3 4e-25 87.6 0.3 3.9 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 KND94174.1 - 4.8e-20 71.8 20.0 4.8e-20 71.8 20.0 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 KND94174.1 - 2.2e-07 31.1 10.0 2.2e-07 31.1 10.0 5.3 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 KND94174.1 - 1.6e-05 24.6 7.8 1.6e-05 24.6 7.8 4.0 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KND94174.1 - 7.5e-05 22.5 8.0 7.5e-05 22.5 8.0 5.5 2 1 5 7 7 7 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KND94174.1 - 0.018 15.0 4.6 0.018 15.0 4.6 6.1 3 3 4 7 7 7 0 Prokaryotic RING finger family 1 DUF773 PF05600.12 KND94176.1 - 0.046 12.4 0.9 0.049 12.4 0.9 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 DUF1178 PF06676.11 KND94176.1 - 3.1 8.2 6.9 1.5e+02 2.7 6.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) TIP49 PF06068.13 KND94177.1 - 1.9e-153 510.8 1.1 2.5e-153 510.4 1.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KND94177.1 - 1.8e-20 72.8 0.3 7.9e-20 70.8 0.2 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KND94177.1 - 1.2e-07 32.2 0.4 0.0002 21.8 0.0 2.8 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KND94177.1 - 1.8e-07 31.0 0.4 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KND94177.1 - 3.8e-06 26.4 0.7 6.9e-06 25.6 0.7 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KND94177.1 - 0.00065 20.1 0.1 0.0017 18.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KND94177.1 - 0.0055 16.1 0.5 0.13 11.6 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KND94177.1 - 0.043 13.6 1.0 0.55 10.0 1.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KND94177.1 - 0.062 13.6 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND94177.1 - 0.089 12.8 0.1 21 5.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF2594 PF10769.9 KND94178.1 - 0.076 13.1 0.2 0.28 11.3 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF2935 PF11155.8 KND94178.1 - 0.08 13.3 1.3 0.33 11.3 0.0 2.7 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) DUF3915 PF13054.6 KND94178.1 - 0.91 9.5 8.2 2.6 8.1 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FlaC_arch PF05377.11 KND94178.1 - 1.9 8.9 10.3 0.56 10.6 0.6 4.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Gp_dh_C PF02800.20 KND94180.1 - 1.2e-69 233.0 0.1 1.7e-69 232.4 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KND94180.1 - 2.3e-38 130.6 0.1 4.5e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 KND94180.1 - 0.01 16.0 0.8 0.031 14.4 0.2 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 KND94180.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GYF PF02213.16 KND94181.1 - 3.8e-10 39.3 2.5 1e-09 37.9 2.5 1.7 1 0 0 1 1 1 1 GYF domain RAP1 PF07218.11 KND94181.1 - 7 4.8 7.5 10 4.3 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UFD1 PF03152.14 KND94182.1 - 3.6e-63 212.1 0.0 4.7e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PRCC PF10253.9 KND94184.1 - 0.051 14.4 5.7 0.096 13.5 5.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF5476 PF17570.2 KND94184.1 - 5.5 7.5 8.5 2.4 8.6 2.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5476) PRCC PF10253.9 KND94185.1 - 0.051 14.4 5.7 0.096 13.5 5.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF5476 PF17570.2 KND94185.1 - 5.5 7.5 8.5 2.4 8.6 2.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Ribosomal_L3 PF00297.22 KND94186.1 - 3.1e-184 612.1 11.0 3.5e-184 612.0 11.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SPO22 PF08631.10 KND94187.1 - 2e-63 214.5 0.9 9.4e-63 212.3 0.5 2.4 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 KND94187.1 - 0.0022 18.2 5.4 0.06 13.6 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 KND94187.1 - 0.012 16.3 0.3 0.92 10.3 0.0 2.8 2 0 0 2 2 2 0 Sel1 repeat Malate_synthase PF01274.22 KND94187.1 - 0.04 12.2 0.0 0.69 8.1 0.0 2.1 2 0 0 2 2 2 0 Malate synthase Nterm_IS4 PF13006.7 KND94187.1 - 0.055 13.7 0.4 25 5.2 0.0 3.9 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal TetR_C_11 PF16859.5 KND94187.1 - 1.3 9.4 5.9 10 6.5 0.1 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Zn_clus PF00172.18 KND94188.1 - 0.68 10.1 7.0 0.077 13.1 1.7 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ald_Xan_dh_C2 PF02738.18 KND94189.1 - 5.2e-205 682.1 0.6 8e-205 681.4 0.6 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Aminotran_1_2 PF00155.21 KND94189.1 - 1.3e-63 215.4 0.0 2.3e-63 214.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_5 PF00941.21 KND94189.1 - 5e-46 156.5 0.0 1.1e-45 155.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Pkinase PF00069.25 KND94189.1 - 1.7e-33 116.1 0.0 3e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ald_Xan_dh_C PF01315.22 KND94189.1 - 6.2e-32 110.2 0.2 1.5e-31 109.0 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KND94189.1 - 2.2e-30 104.5 0.1 5.3e-30 103.3 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 KND94189.1 - 6.7e-29 100.1 0.9 5.2e-28 97.2 0.1 2.7 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Pkinase_Tyr PF07714.17 KND94189.1 - 1.6e-20 73.5 0.0 2.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fer2 PF00111.27 KND94189.1 - 4.6e-07 29.7 2.0 5e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Kinase-like PF14531.6 KND94189.1 - 1.1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Beta_elim_lyase PF01212.21 KND94189.1 - 0.0014 18.0 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KND94189.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Kdo PF06293.14 KND94189.1 - 0.0076 15.6 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cys_Met_Meta_PP PF01053.20 KND94189.1 - 0.037 12.6 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme T2SSI PF02501.17 KND94189.1 - 0.079 13.1 0.0 0.86 9.8 0.0 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein I JmjC PF02373.22 KND94190.1 - 8.1e-38 129.4 0.3 2.6e-37 127.7 0.3 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KND94190.1 - 8.9e-20 70.9 6.5 1.6e-19 70.1 6.5 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KND94190.1 - 1.3e-18 67.0 5.2 1.3e-18 67.0 5.2 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 KND94190.1 - 2.6e-13 49.7 1.4 8e-13 48.1 1.4 1.9 1 0 0 1 1 1 1 jmjN domain Astro_capsid_p PF12226.8 KND94190.1 - 0.047 12.9 0.5 0.58 9.3 0.1 2.5 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Abhydrolase_3 PF07859.13 KND94191.1 - 5.4e-34 117.9 0.0 1.6e-22 80.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KND94191.1 - 0.056 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Ufd2P_core PF10408.9 KND94194.1 - 3.8e-207 689.8 12.7 1.2e-206 688.1 12.3 1.9 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 KND94194.1 - 1.6e-25 89.1 7.4 2.4e-25 88.5 0.9 3.4 3 0 0 3 3 3 1 U-box domain zf-TRAF PF02176.18 KND94194.1 - 3.2e-09 37.3 25.9 8.4e-07 29.6 1.5 3.6 1 1 2 3 3 3 2 TRAF-type zinc finger zf-RING_UBOX PF13445.6 KND94194.1 - 1.6e-08 34.4 7.8 1.4e-06 28.2 8.5 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KND94194.1 - 5.4e-08 32.6 5.6 5.4e-08 32.6 5.6 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND94194.1 - 5.9e-08 32.5 4.9 5.9e-08 32.5 4.9 3.0 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KND94194.1 - 3.5e-07 30.3 6.5 3.5e-07 30.3 6.5 3.1 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KND94194.1 - 1.2e-06 28.3 2.2 1.2e-06 28.3 2.2 3.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND94194.1 - 3.7e-06 27.2 5.5 3.7e-06 27.2 5.5 3.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KND94194.1 - 1.5e-05 24.8 2.5 1.5e-05 24.8 2.5 2.9 2 1 1 3 3 1 1 zinc-RING finger domain zf-Nse PF11789.8 KND94194.1 - 0.029 14.2 7.4 0.72 9.7 5.8 3.0 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KND94194.1 - 0.056 13.5 1.0 0.17 11.9 1.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CCDC-167 PF15188.6 KND94194.1 - 0.64 10.4 6.9 0.55 10.6 0.9 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Remorin_C PF03763.13 KND94194.1 - 3.7 7.5 10.5 1.4 8.8 0.1 3.3 3 0 0 3 3 3 0 Remorin, C-terminal region zf-RING_10 PF16685.5 KND94194.1 - 4.8 7.4 11.8 0.12 12.6 4.3 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 OmpH PF03938.14 KND94194.1 - 5.4 7.3 6.7 6.1 7.2 1.4 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-TRAF_2 PF15965.5 KND94194.1 - 8.6 6.9 23.5 2.4 8.7 0.1 3.5 1 1 2 3 3 3 0 TRAF-like zinc-finger A_deaminase PF00962.22 KND94195.1 - 2.7e-29 102.5 0.0 2.3e-26 92.9 0.0 2.0 1 1 1 2 2 2 2 Adenosine/AMP deaminase PIN_10 PF18478.1 KND94195.1 - 0.092 13.0 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 PIN like domain Fungal_trans PF04082.18 KND94196.1 - 3.4e-24 85.3 0.4 6.6e-24 84.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94196.1 - 7.1e-08 32.5 13.7 1.4e-07 31.5 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KND94197.1 - 7e-31 107.5 0.0 1.3e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) His_Phos_2 PF00328.22 KND94197.1 - 0.00079 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_1 PF00170.21 KND94198.1 - 1.1e-07 31.9 11.0 1.1e-07 31.9 11.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KND94198.1 - 0.001 19.1 10.2 0.0026 17.8 10.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.6 KND94198.1 - 5 6.4 8.0 9.5 5.5 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNAP PF14938.6 KND94199.1 - 3.9e-93 312.0 12.6 4.3e-93 311.8 12.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KND94199.1 - 5.1e-10 39.5 7.3 6.7e-05 23.1 0.3 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KND94199.1 - 0.0011 18.9 12.4 3 8.2 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KND94199.1 - 0.0011 19.4 7.0 2.9 8.7 0.1 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND94199.1 - 0.0025 17.9 6.1 2.1 8.8 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND94199.1 - 0.013 16.3 9.2 2.9 8.9 0.2 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KND94199.1 - 0.059 13.9 0.4 0.059 13.9 0.4 4.0 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF2521 PF10730.9 KND94199.1 - 0.061 13.4 0.1 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) TPR_7 PF13176.6 KND94199.1 - 0.061 13.4 4.8 2.5 8.3 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KND94199.1 - 0.2 11.8 6.2 1.6 8.9 0.3 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND94199.1 - 0.32 10.9 8.7 13 5.8 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 KND94200.1 - 6.2e-12 45.6 1.5 1.5e-11 44.4 1.5 1.6 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit tRNA-synt_1d PF00750.19 KND94201.1 - 7.7e-95 317.8 3.2 1.3e-94 317.0 3.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KND94201.1 - 3.2e-24 85.4 0.0 6.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KND94201.1 - 0.0004 20.9 0.0 0.00095 19.7 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain AMP-binding PF00501.28 KND94202.1 - 1.1e-21 77.0 0.1 1.3e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme L51_S25_CI-B8 PF05047.16 KND94203.1 - 1e-15 57.4 0.1 1.6e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PPI_Ypi1 PF07491.11 KND94205.1 - 4.4e-25 87.3 2.8 1.5e-24 85.5 2.8 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor SPESP1 PF15754.5 KND94205.1 - 0.0051 16.0 1.2 0.009 15.2 1.2 1.4 1 0 0 1 1 1 1 Sperm equatorial segment protein 1 SAPS PF04499.15 KND94205.1 - 0.49 9.1 3.4 0.51 9.1 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.9 KND94205.1 - 3.9 5.9 6.1 4.7 5.6 6.1 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KND94205.1 - 8.8 4.5 5.6 9.9 4.3 5.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TP53IP5 PF15331.6 KND94205.1 - 9.4 6.3 9.8 0.33 11.1 1.6 2.0 1 1 1 2 2 2 0 Cellular tumour antigen p53-inducible 5 MMR_HSR1 PF01926.23 KND94206.1 - 7.8e-05 22.7 0.0 0.45 10.6 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase HECT PF00632.25 KND94207.1 - 2.5e-75 253.8 0.0 3.7e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.22 KND94207.1 - 0.23 11.4 1.0 0.47 10.4 1.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3712 PF12505.8 KND94208.1 - 1.5e-06 28.5 0.0 5.8e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3712) Na_Ca_ex PF01699.24 KND94209.1 - 5.7e-22 78.3 28.3 8.9e-15 54.9 12.7 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 KND94209.1 - 2.3e-15 57.0 12.2 2.3e-15 57.0 12.2 4.3 3 0 0 3 3 3 1 Inner membrane component domain Curto_V2 PF07325.11 KND94209.1 - 0.25 11.2 1.2 0.47 10.3 1.2 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF1989 PF09347.10 KND94211.1 - 3e-61 205.9 0.0 3.8e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AAA PF00004.29 KND94212.1 - 1.5e-43 148.4 0.0 2.4e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND94212.1 - 4.5e-15 55.2 0.0 9.7e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KND94212.1 - 3.6e-07 30.2 0.0 9.7e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KND94212.1 - 5.7e-07 29.8 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 KND94212.1 - 9.4e-07 28.7 2.1 2.4e-06 27.4 2.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 KND94212.1 - 5.8e-06 26.8 0.0 0.00011 22.6 0.1 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KND94212.1 - 6.2e-05 23.3 0.3 0.016 15.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KND94212.1 - 9.6e-05 22.2 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KND94212.1 - 0.00059 20.4 0.1 0.015 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KND94212.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KND94212.1 - 0.0014 18.8 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 KND94212.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KND94212.1 - 0.0028 17.3 0.1 0.01 15.4 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain ATPase PF06745.13 KND94212.1 - 0.0067 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KND94212.1 - 0.0072 15.7 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KND94212.1 - 0.0099 15.7 0.0 0.029 14.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KND94212.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KND94212.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KND94212.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KND94212.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 KND94212.1 - 0.023 14.1 0.0 0.096 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 KND94212.1 - 0.027 14.2 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 KND94212.1 - 0.03 14.0 0.0 0.077 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 KND94212.1 - 0.033 14.6 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 KND94212.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND94212.1 - 0.049 13.1 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2072 PF09845.9 KND94212.1 - 0.049 13.9 0.1 0.098 12.9 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Parvo_NS1 PF01057.17 KND94212.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HR1 PF02185.16 KND94212.1 - 0.11 12.7 1.0 0.26 11.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat Zeta_toxin PF06414.12 KND94212.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 KND94212.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KND94212.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 1 1 2 2 2 0 NACHT domain Tcp11 PF05794.13 KND94213.1 - 9.2e-99 331.5 0.2 9.2e-99 331.5 0.2 2.5 3 1 1 4 4 4 1 T-complex protein 11 DUF2274 PF10038.9 KND94213.1 - 0.077 13.5 1.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) UPF0242 PF06785.11 KND94213.1 - 1.5 8.9 7.3 2.9 7.9 7.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Y_phosphatase PF00102.27 KND94214.1 - 3.3e-59 200.3 0.0 8.3e-50 169.5 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 KND94214.1 - 8e-10 39.2 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KND94214.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KND94214.1 - 0.097 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain ERAP1_C PF11838.8 KND94215.1 - 6.9e-86 288.6 0.0 1.7e-85 287.3 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KND94215.1 - 8.5e-80 267.4 1.4 1.2e-79 266.9 1.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KND94215.1 - 9.1e-48 162.9 0.9 1.5e-47 162.2 0.4 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 KND94215.1 - 0.013 15.5 0.0 0.057 13.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DUF45 PF01863.17 KND94215.1 - 0.02 15.0 0.1 0.12 12.4 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function DUF45 zf-FCS PF06467.14 KND94216.1 - 0.023 14.6 1.6 0.036 14.0 0.6 1.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF1467 PF07330.12 KND94217.1 - 1.3 9.0 7.7 0.11 12.5 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) COesterase PF00135.28 KND94218.1 - 7.2e-78 262.7 0.0 9.9e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KND94218.1 - 2.4e-05 24.3 0.4 0.00016 21.6 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF5525 PF17663.1 KND94218.1 - 0.16 10.0 7.1 0.23 9.5 7.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) S36_mt PF10937.8 KND94219.1 - 1.2e-39 136.4 1.8 1.2e-39 136.4 1.8 1.5 2 0 0 2 2 2 1 Ribosomal protein S36, mitochondrial DUF4701 PF15773.5 KND94219.1 - 0.051 12.6 0.2 0.064 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) AA_permease PF00324.21 KND94221.1 - 3.4e-146 487.6 43.4 5.8e-138 460.5 29.5 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KND94221.1 - 2e-32 112.6 32.6 2e-32 112.6 32.6 2.9 1 1 2 3 3 3 3 Amino acid permease LSM PF01423.22 KND94221.1 - 0.23 11.2 0.1 0.43 10.3 0.1 1.3 1 0 0 1 1 1 0 LSM domain DUF4579 PF15158.6 KND94221.1 - 1.4 8.6 3.0 22 4.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) MFS_1 PF07690.16 KND94222.1 - 1.6e-19 70.1 25.7 2.7e-19 69.3 25.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KND94222.1 - 2e-09 37.3 5.8 2e-09 37.3 5.8 2.9 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2208 PF09973.9 KND94222.1 - 0.049 13.3 0.5 0.34 10.5 0.1 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) DUF1345 PF07077.11 KND94222.1 - 0.13 11.9 4.1 0.39 10.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1345) DUF3493 PF11998.8 KND94222.1 - 0.17 12.1 0.9 3.8 7.8 1.6 2.8 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF2304 PF10066.9 KND94222.1 - 9 6.6 7.7 4.3 7.6 0.8 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Aminotran_1_2 PF00155.21 KND94223.1 - 7.6e-80 268.8 0.0 9.5e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GHMP_kinases_N PF00288.26 KND94224.1 - 3.7e-16 59.1 0.0 8e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KND94224.1 - 3.2e-08 33.8 0.0 8.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KND94224.1 - 0.003 17.1 0.1 0.006 16.1 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PKcGMP_CC PF16808.5 KND94224.1 - 0.91 9.4 4.1 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1992 PF09350.10 KND94225.1 - 9.6e-19 67.3 0.4 2.1e-18 66.2 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Sugar_tr PF00083.24 KND94226.1 - 2.3e-86 290.5 17.7 2.6e-86 290.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND94226.1 - 2.3e-13 49.8 30.2 1.1e-09 37.8 8.5 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KND94226.1 - 0.0016 17.3 5.1 0.0016 17.3 5.1 2.4 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 KND94226.1 - 0.0055 15.3 1.6 0.0055 15.3 1.6 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF1478 PF07349.11 KND94226.1 - 0.12 12.3 1.7 1.9 8.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1478) DUF4131 PF13567.6 KND94226.1 - 2.9 7.5 13.1 2 8.0 2.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.16 KND94228.1 - 4.7e-27 94.8 39.3 4.4e-25 88.3 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94228.1 - 1.2e-16 60.7 27.7 2e-16 60.0 27.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter LacAB_rpiB PF02502.18 KND94228.1 - 0.081 12.9 0.9 0.14 12.2 0.9 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase TPR_1 PF00515.28 KND94230.1 - 1.8e-46 154.1 31.9 1.2e-07 31.3 0.1 10.4 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 KND94230.1 - 8.7e-41 134.8 22.4 8e-06 25.6 0.0 10.0 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 KND94230.1 - 3.2e-27 92.4 19.9 9.1e-05 22.4 0.0 10.6 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KND94230.1 - 4.4e-23 81.7 16.3 1.6e-06 28.6 0.5 6.8 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KND94230.1 - 8.7e-23 79.0 20.8 0.0019 18.4 0.1 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 KND94230.1 - 2.1e-22 77.9 12.4 0.00013 22.5 0.0 8.7 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KND94230.1 - 2.5e-20 72.8 21.2 0.00033 21.1 0.4 7.1 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KND94230.1 - 2.5e-16 59.0 30.6 6.1e-05 22.6 1.5 9.3 5 3 4 9 9 9 5 TPR repeat TPR_6 PF13174.6 KND94230.1 - 2e-15 56.3 18.1 0.021 15.5 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 KND94230.1 - 2.5e-15 56.5 25.8 0.0026 18.0 0.8 7.2 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 KND94230.1 - 1.6e-12 47.4 12.0 0.021 15.0 0.1 5.7 2 2 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KND94230.1 - 1e-09 37.7 12.2 0.73 10.0 0.0 8.8 9 1 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KND94230.1 - 1e-09 38.5 9.5 3.2e-07 30.5 1.2 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KND94230.1 - 1.5e-08 34.2 8.9 0.19 10.9 1.1 5.3 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_21 PF09976.9 KND94230.1 - 0.0021 17.8 12.6 0.067 12.9 1.4 4.3 4 2 0 4 4 4 2 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 KND94230.1 - 0.025 14.3 3.4 0.13 11.9 0.2 2.8 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 KND94230.1 - 0.046 13.8 0.4 20 5.4 0.0 4.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 KND94230.1 - 0.28 11.1 14.5 8.5 6.4 0.1 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat NuiA PF07924.11 KND94231.1 - 0.0027 18.1 0.1 1.3 9.4 0.0 2.4 1 1 0 2 2 2 2 Nuclease A inhibitor-like protein Reprolysin_5 PF13688.6 KND94232.1 - 6e-58 196.2 2.5 1.8e-57 194.7 2.5 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KND94232.1 - 6.1e-49 166.4 0.5 1.1e-48 165.6 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KND94232.1 - 2.5e-48 164.6 0.9 5.5e-48 163.4 0.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 KND94232.1 - 5.8e-17 62.3 29.7 5.8e-17 62.3 29.7 4.9 3 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 KND94232.1 - 4.4e-10 40.1 0.0 1.1e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KND94232.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KND94232.1 - 0.0031 18.0 9.1 0.0031 18.0 9.1 5.1 2 1 2 4 4 4 1 ADAM cysteine-rich domain WD40 PF00400.32 KND94233.1 - 1e-09 38.8 9.9 0.013 16.4 0.0 7.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94233.1 - 7.7e-08 32.5 0.1 0.0027 18.0 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1751 PF08551.10 KND94236.1 - 9.1e-26 90.3 5.4 1.8e-25 89.4 5.4 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KND94236.1 - 0.17 11.9 10.3 0.3 11.1 10.3 1.3 1 0 0 1 1 1 0 Rhomboid family Chorismate_bind PF00425.18 KND94237.1 - 4.2e-91 305.1 0.0 1.2e-89 300.3 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KND94237.1 - 2.3e-25 89.5 0.0 2.7e-21 76.3 0.0 3.8 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.18 KND94237.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Hexapep PF00132.24 KND94240.1 - 7.3e-07 28.7 1.1 0.0018 18.0 0.2 3.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KND94240.1 - 0.00014 20.9 0.1 0.00022 20.3 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 KND94240.1 - 0.0013 17.0 0.0 0.0019 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KND94240.1 - 0.0015 18.9 0.0 0.0037 17.6 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KND94240.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase DUF5554 PF17709.1 KND94240.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Hexapep_2 PF14602.6 KND94240.1 - 1.1 9.1 5.5 3.8 7.3 0.1 3.0 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase ATG27 PF09451.10 KND94241.1 - 1.5e-99 333.1 0.0 1.9e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KND94241.1 - 0.00025 21.1 0.1 0.29 11.2 0.0 2.9 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Spt20 PF12090.8 KND94242.1 - 4.4e-45 154.1 0.0 4.4e-45 154.1 0.0 7.2 5 1 2 7 7 7 1 Spt20 family RdRP PF05183.12 KND94243.1 - 1.8e-186 621.3 0.0 2.4e-186 620.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Abhydrolase_1 PF00561.20 KND94244.1 - 1.9e-12 47.4 0.0 1.2e-11 44.8 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 KND94244.1 - 4.3e-08 32.2 0.0 6.5e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 KND94244.1 - 7.5e-06 25.4 0.0 1.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 KND94244.1 - 0.0059 16.3 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-C2H2 PF00096.26 KND94245.1 - 0.0028 18.0 24.4 0.011 16.1 7.4 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND94245.1 - 0.004 17.9 14.5 0.13 13.2 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND94245.1 - 0.012 16.0 1.4 0.012 16.0 1.4 3.6 4 0 0 4 4 4 0 Zinc-finger double domain FOXP-CC PF16159.5 KND94245.1 - 0.6 10.8 4.6 0.26 11.9 1.7 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Gpr1_Fun34_YaaH PF01184.19 KND94246.1 - 4.3e-18 65.7 22.2 5.9e-17 62.0 22.2 2.0 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Tmemb_14 PF03647.13 KND94246.1 - 7.8 7.3 11.9 7 7.5 10.2 1.9 1 1 1 2 2 2 0 Transmembrane proteins 14C Amidohydro_2 PF04909.14 KND94247.1 - 1.7e-31 110.1 0.1 2.2e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF1965 PF09248.10 KND94247.1 - 0.15 11.9 0.2 0.78 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1965) Mre11_DNA_bind PF04152.14 KND94249.1 - 3.6e-54 183.6 0.8 3.6e-54 183.6 0.8 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KND94249.1 - 3.1e-16 60.5 1.5 5.6e-16 59.7 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND94249.1 - 1.1e-05 25.7 0.0 7.3e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Stm1_N PF09598.10 KND94249.1 - 2.3 9.1 25.9 5.5 7.9 8.9 2.7 2 0 0 2 2 2 0 Stm1 BHD_2 PF10404.9 KND94249.1 - 6.7 7.8 11.1 1 10.4 2.3 3.1 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 2 MFS_1 PF07690.16 KND94250.1 - 8.2e-15 54.6 26.4 8.2e-15 54.6 26.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KND94250.1 - 9.9e-05 21.9 7.3 9.9e-05 21.9 7.3 2.7 2 1 0 2 2 2 1 Nodulin-like NACHT_N PF17100.5 KND94251.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KND94251.1 - 0.0001 22.3 0.3 0.00039 20.4 0.3 2.0 1 1 0 1 1 1 1 NACHT domain Viral_helicase1 PF01443.18 KND94251.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KND94251.1 - 0.034 14.5 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PDEase_I_N PF08499.12 KND94251.1 - 0.18 11.7 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal F-box PF00646.33 KND94252.1 - 0.00023 21.0 1.7 0.00081 19.2 0.2 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KND94252.1 - 0.065 13.1 3.3 0.064 13.2 1.2 2.2 1 1 1 2 2 2 0 F-box-like Inositol_P PF00459.25 KND94253.1 - 2.4e-34 119.1 0.1 8.2e-34 117.4 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family TetR_C_14 PF17754.1 KND94253.1 - 0.097 12.6 1.3 0.44 10.5 0.3 2.3 2 0 0 2 2 2 0 MftR C-terminal domain Epimerase PF01370.21 KND94254.1 - 1.3e-20 73.9 0.0 3.8e-20 72.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND94254.1 - 2.9e-18 66.4 0.2 1e-12 48.1 0.1 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KND94254.1 - 3.3e-08 33.0 0.0 5.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KND94254.1 - 1.3e-07 31.1 1.7 1.7e-05 24.1 0.1 2.9 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KND94254.1 - 3.6e-05 23.1 1.2 7.1e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein RCDG1 PF15725.5 KND94254.1 - 9.3 6.8 18.0 0.22 12.0 3.0 3.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Band_7 PF01145.25 KND94255.1 - 1.8e-15 57.4 0.1 1.8e-15 57.4 0.1 3.3 2 2 0 2 2 2 1 SPFH domain / Band 7 family Amidohydro_1 PF01979.20 KND94255.1 - 0.0031 16.9 2.7 0.0053 16.1 2.7 1.4 1 0 0 1 1 1 1 Amidohydrolase family BRO1 PF03097.18 KND94256.1 - 3e-115 385.2 0.1 7.4e-115 383.9 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KND94256.1 - 9.5e-61 205.7 9.9 1.7e-56 191.7 0.9 3.1 2 2 1 3 3 3 2 ALIX V-shaped domain binding to HIV K-box PF01486.17 KND94256.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 K-box region LSM PF01423.22 KND94257.1 - 5.5e-13 48.4 0.0 9.3e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain MMU163 PF17119.5 KND94258.1 - 5.5e-70 235.4 2.5 1e-50 172.2 0.9 2.1 2 0 0 2 2 2 2 Mitochondrial protein up-regulated during meiosis Ras PF00071.22 KND94259.1 - 3.4e-65 218.6 0.4 4e-65 218.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND94259.1 - 9.1e-36 122.7 0.1 1.7e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND94259.1 - 4.9e-16 58.7 0.1 5.9e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KND94259.1 - 2.2e-05 24.5 0.0 0.0001 22.3 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND94259.1 - 2.8e-05 24.1 0.6 0.13 12.1 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KND94259.1 - 0.00011 21.8 0.3 0.0003 20.4 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KND94259.1 - 0.00032 20.1 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KND94259.1 - 0.00074 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KND94259.1 - 0.00096 19.6 0.0 0.22 11.9 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KND94259.1 - 0.0043 16.6 0.0 0.027 14.0 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KND94259.1 - 0.01 16.2 0.0 0.014 15.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KND94259.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KND94259.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 KND94259.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 KND94259.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 KND94259.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND94259.1 - 0.081 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KND94259.1 - 0.094 13.2 0.0 0.16 12.5 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KND94259.1 - 0.13 11.8 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNase_PH PF01138.21 KND94262.1 - 1.3e-12 48.4 0.0 2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KND94262.1 - 0.0014 18.6 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 ATE_C PF04377.15 KND94263.1 - 1.6e-45 155.1 0.3 2.6e-45 154.3 0.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KND94263.1 - 2e-21 76.1 0.1 4.2e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KND94263.1 - 0.08 13.1 0.1 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NUDIX PF00293.28 KND94264.1 - 3.7e-17 62.6 0.6 4.6e-17 62.3 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 KND94265.1 - 9.2e-64 213.8 0.0 1.8e-45 154.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND94265.1 - 8.1e-15 54.4 1.2 2.4e-06 27.2 0.0 3.3 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KND94265.1 - 4.9e-11 43.3 0.4 0.00021 21.7 0.0 4.1 3 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KND94265.1 - 3.8e-10 39.9 0.1 2.6e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND94265.1 - 1.3e-08 35.1 0.0 0.0019 18.3 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_2 PF07724.14 KND94265.1 - 2.9e-08 34.0 0.0 1.3e-06 28.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KND94265.1 - 1.4e-07 31.4 0.0 0.00043 20.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KND94265.1 - 2.9e-07 30.8 0.0 0.0017 18.7 0.0 3.9 3 1 0 3 3 2 1 AAA domain AAA_25 PF13481.6 KND94265.1 - 1.7e-05 24.5 0.5 2.3 7.8 0.0 4.5 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.6 KND94265.1 - 2.2e-05 24.9 0.4 0.11 12.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 KND94265.1 - 2.8e-05 23.4 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_18 PF13238.6 KND94265.1 - 3.1e-05 24.5 0.0 0.36 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KND94265.1 - 8.2e-05 22.0 0.0 0.073 12.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 KND94265.1 - 0.00029 20.8 0.1 0.36 10.7 0.0 2.7 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 KND94265.1 - 0.0003 20.5 0.0 0.19 11.4 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KND94265.1 - 0.00035 20.9 0.0 0.078 13.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 KND94265.1 - 0.00073 19.3 0.1 0.09 12.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 KND94265.1 - 0.00074 19.8 0.1 1.9 8.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain TsaE PF02367.17 KND94265.1 - 0.00076 19.5 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 KND94265.1 - 0.00086 19.3 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 KND94265.1 - 0.0015 19.0 0.0 0.39 11.2 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 KND94265.1 - 0.002 17.7 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 KND94265.1 - 0.0023 17.2 2.3 0.033 13.5 0.0 3.5 4 0 0 4 4 4 1 Zeta toxin Cytidylate_kin PF02224.18 KND94265.1 - 0.0024 17.6 0.1 0.29 10.8 0.1 2.4 2 0 0 2 2 2 1 Cytidylate kinase Mg_chelatase PF01078.21 KND94265.1 - 0.004 16.6 0.3 0.16 11.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KND94265.1 - 0.0044 16.8 0.1 0.23 11.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KND94265.1 - 0.0047 16.9 0.3 1.8 8.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.6 KND94265.1 - 0.0063 16.6 0.0 0.098 12.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 KND94265.1 - 0.015 15.1 0.1 0.66 9.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KND94265.1 - 0.062 13.0 0.2 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 KND94265.1 - 0.093 12.1 0.0 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein IPT PF01745.16 KND94265.1 - 0.094 12.1 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase ResIII PF04851.15 KND94265.1 - 0.094 12.7 0.0 0.29 11.1 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 KND94265.1 - 0.12 12.2 0.1 22 4.9 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KND94265.1 - 0.15 11.2 0.0 3.4 6.8 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_3 PF07726.11 KND94265.1 - 0.16 11.8 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KND94265.1 - 0.21 11.9 0.4 8.7 6.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 KND94265.1 - 0.21 10.9 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC Cytochrom_C PF00034.21 KND94266.1 - 1.2e-12 48.8 0.1 1.6e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KND94266.1 - 9.4e-09 35.5 2.6 2.7e-08 34.0 2.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KND94266.1 - 0.0015 18.2 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 KND94266.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Porphobil_deam PF01379.20 KND94267.1 - 5.3e-07 29.4 0.1 5.4e-07 29.3 0.1 1.0 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain CN_hydrolase PF00795.22 KND94268.1 - 2e-41 142.1 0.1 3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3433 PF11915.8 KND94268.1 - 0.34 11.4 1.7 1.7 9.1 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) CPSF73-100_C PF11718.8 KND94269.1 - 7.5e-88 293.7 0.0 1.1e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KND94269.1 - 6.4e-30 103.7 0.0 1.6e-29 102.4 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KND94269.1 - 1.3e-18 67.1 0.1 2.7e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KND94269.1 - 4.4e-18 66.0 1.0 9e-18 65.0 1.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KND94269.1 - 5.1e-11 42.3 0.1 9.9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KND94269.1 - 2.3e-06 27.3 0.7 5.3e-06 26.1 0.7 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KND94269.1 - 5.1e-06 26.5 0.2 1.2e-05 25.3 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.14 KND94270.1 - 1.6e-29 103.6 4.8 1.1e-24 87.7 3.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family LRR_6 PF13516.6 KND94271.1 - 0.0051 16.8 5.1 0.59 10.3 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 KND94271.1 - 0.011 16.1 0.1 0.87 10.1 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KND94271.1 - 0.12 13.0 2.7 1.5e+02 3.6 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat V_ATPase_I PF01496.19 KND94272.1 - 0 1041.5 0.1 0 1041.3 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DASH_Dam1 PF08653.10 KND94272.1 - 0.024 14.4 4.9 16 5.4 0.1 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 YojJ PF10372.9 KND94272.1 - 0.082 13.0 0.3 38 4.5 0.2 3.5 3 1 1 4 4 3 0 Bacterial membrane-spanning protein N-terminus EzrA PF06160.12 KND94272.1 - 0.09 10.9 7.7 0.85 7.7 0.8 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Tnp_22_trimer PF17489.2 KND94272.1 - 0.094 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain CheZ PF04344.13 KND94272.1 - 0.098 12.6 3.6 0.34 10.8 0.4 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Spc7 PF08317.11 KND94272.1 - 0.13 11.1 4.9 3 6.6 0.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Serine_rich PF08824.10 KND94272.1 - 0.16 11.9 2.3 0.54 10.2 0.3 2.3 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF3552 PF12072.8 KND94272.1 - 0.23 10.8 4.0 6.2 6.2 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF1664 PF07889.12 KND94272.1 - 0.26 11.3 4.3 3.6 7.6 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 KND94272.1 - 0.27 11.3 1.3 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DHR10 PF18595.1 KND94272.1 - 0.45 10.6 8.1 6.2 6.9 3.5 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain DUF16 PF01519.16 KND94272.1 - 0.49 10.9 4.5 32 5.1 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 KND94272.1 - 0.54 10.2 3.6 13 5.8 0.2 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF4988 PF16378.5 KND94272.1 - 0.56 9.9 2.1 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function Laminin_II PF06009.12 KND94272.1 - 0.6 10.1 6.0 7 6.7 0.2 2.5 2 0 0 2 2 2 0 Laminin Domain II Phage_GP20 PF06810.11 KND94272.1 - 0.61 9.9 2.8 20 5.0 0.1 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 Filament PF00038.21 KND94272.1 - 0.64 9.5 11.8 2 7.9 1.0 2.7 2 1 0 2 2 2 0 Intermediate filament protein Fmp27_WPPW PF10359.9 KND94272.1 - 1 8.1 4.6 2.5 6.9 0.4 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain HMMR_N PF15905.5 KND94272.1 - 1.1 8.7 4.6 10 5.5 0.8 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CLZ PF16526.5 KND94272.1 - 1.1 9.6 7.8 2.4 8.6 0.4 2.7 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 KND94272.1 - 1.7 8.1 7.7 0.85 9.0 1.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 KND94272.1 - 2 8.5 7.2 1.1 9.3 1.1 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 KND94272.1 - 2.3 8.7 5.6 9.4 6.8 0.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 KND94272.1 - 2.4 8.7 6.6 7.6 7.0 1.1 3.1 2 1 1 3 3 3 0 Snapin/Pallidin BLOC1_2 PF10046.9 KND94272.1 - 8.1 6.8 6.7 6.6 7.1 0.7 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prenyltransf PF01255.19 KND94273.1 - 5.3e-80 268.1 0.0 7.2e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 KND94273.1 - 0.096 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ING PF12998.7 KND94274.1 - 3.2e-07 30.9 0.1 0.00082 19.9 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KND94274.1 - 9.9e-07 28.6 7.4 1.6e-06 27.9 7.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KND94274.1 - 0.14 12.5 0.9 0.29 11.4 0.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SelP_N PF04592.14 KND94274.1 - 3.7 6.9 7.4 8.6 5.7 7.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region OSCP PF00213.18 KND94275.1 - 9.8e-48 162.5 0.4 1.2e-47 162.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit rve PF00665.26 KND94275.1 - 0.086 13.0 1.1 0.25 11.5 0.9 1.8 2 0 0 2 2 2 0 Integrase core domain Glyco_hydro_63 PF03200.16 KND94276.1 - 1.2e-08 34.2 10.2 3e-07 29.6 0.3 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 KND94276.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Histone PF00125.24 KND94277.1 - 3.9e-14 53.1 0.1 3.9e-14 53.1 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KND94277.1 - 4.2e-12 45.6 0.1 8.9e-12 44.5 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KND94277.1 - 0.00022 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KND94278.1 - 1.2e-18 67.7 0.0 1.6e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KND94278.1 - 8.8e-13 47.8 0.1 1.9e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KND94278.1 - 2.7e-05 24.4 0.0 4.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 KND94279.1 - 6.5e-11 42.0 0.2 1.2e-10 41.2 0.2 1.4 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KND94279.1 - 2.5e-05 24.0 0.0 5.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NR_Repeat PF14046.6 KND94279.1 - 0.57 10.4 3.0 0.94 9.7 1.6 2.1 1 1 1 2 2 2 0 Nuclear receptor repeat Acetyltransf_10 PF13673.7 KND94280.1 - 4.3e-11 42.9 0.0 5.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KND94280.1 - 3e-07 30.7 0.0 4.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KND94280.1 - 9.2e-06 26.0 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 KND94280.1 - 0.013 15.6 4.6 0.017 15.2 2.5 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DUF445 PF04286.12 KND94281.1 - 0.017 15.0 5.1 0.048 13.5 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) HEPN_Swt1 PF18731.1 KND94281.1 - 0.028 14.8 0.9 0.1 12.9 0.3 2.3 2 0 0 2 2 2 0 Swt1-like HEPN BC10 PF06726.12 KND94282.1 - 1.3e-13 51.0 7.5 2.7e-13 49.9 7.5 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Fungal_trans_2 PF11951.8 KND94286.1 - 3.1e-45 154.6 0.0 3.9e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94286.1 - 2.1e-05 24.5 3.7 3.7e-05 23.8 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2183 PF09949.9 KND94288.1 - 1.2e-10 41.6 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Uso1_p115_head PF04869.14 KND94290.1 - 9.4e-113 376.4 0.0 1.9e-112 375.4 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KND94290.1 - 1.9e-13 50.9 10.9 1.9e-13 50.9 10.9 3.2 2 1 1 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Methyltransf_25 PF13649.6 KND94290.1 - 4.7e-11 43.3 0.3 2.3e-10 41.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND94290.1 - 1.7e-09 38.2 1.3 8.3e-09 36.0 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 KND94290.1 - 1.3e-08 34.6 0.1 4.2e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KND94290.1 - 2.7e-08 33.8 0.1 1.1e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND94290.1 - 2.9e-05 24.0 0.0 7.9e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KND94290.1 - 0.00013 21.5 0.3 0.00013 21.5 0.3 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KND94290.1 - 0.00015 22.4 0.0 0.00051 20.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 KND94290.1 - 0.00089 19.2 0.1 0.0023 17.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Mo25 PF08569.11 KND94290.1 - 0.042 13.2 4.0 8 5.7 0.0 3.1 3 0 0 3 3 3 0 Mo25-like TehB PF03848.14 KND94290.1 - 0.057 12.8 0.1 0.25 10.7 0.0 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TehB zf-C2H2_6 PF13912.6 KND94290.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger TFIIA PF03153.13 KND94290.1 - 1.7 8.5 11.9 2.7 7.9 11.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OPT PF03169.15 KND94291.1 - 1.7e-122 410.1 11.7 2.1e-121 406.5 11.7 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Vps55 PF04133.14 KND94291.1 - 0.0081 16.1 4.1 0.14 12.1 2.9 2.8 2 0 0 2 2 2 1 Vacuolar protein sorting 55 XRN_M PF17846.1 KND94292.1 - 1.1e-134 449.8 0.0 3.7e-134 448.0 0.0 1.8 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KND94292.1 - 6e-97 323.8 0.0 8.8e-97 323.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 KND94292.1 - 0.14 12.3 2.7 0.3 11.2 2.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KND94292.1 - 0.18 11.7 2.4 0.41 10.5 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle LtrA PF06772.11 KND94293.1 - 9.5e-52 176.4 19.2 1.2e-51 176.0 19.2 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2189 PF09955.9 KND94293.1 - 0.0094 16.2 3.5 0.39 11.0 0.4 2.9 2 0 0 2 2 2 2 Predicted integral membrane protein (DUF2189) Zn_clus PF00172.18 KND94295.1 - 6.2e-08 32.6 9.4 1.1e-07 31.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND94295.1 - 1.1e-06 27.7 0.3 1.9e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 KND94297.1 - 7.9e-57 192.6 0.4 1.5e-56 191.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core MIG-14_Wnt-bd PF06664.12 KND94298.1 - 0.072 12.3 12.5 0.14 11.3 12.5 1.5 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion TspO_MBR PF03073.15 KND94298.1 - 6.6 6.8 12.6 1.6 8.8 4.6 2.5 2 0 0 2 2 2 0 TspO/MBR family zf-RING_2 PF13639.6 KND94299.1 - 9.6e-13 48.2 4.5 1.7e-12 47.5 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KND94299.1 - 9.7e-12 44.4 2.2 2e-11 43.4 2.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND94299.1 - 8.6e-08 31.9 4.0 1.4e-07 31.2 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND94299.1 - 6.1e-07 29.2 2.1 1e-06 28.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KND94299.1 - 5.6e-06 26.6 4.8 1.7e-05 25.0 4.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KND94299.1 - 6.2e-05 22.9 1.7 0.00011 22.1 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KND94299.1 - 6.7e-05 22.7 3.5 0.00012 21.9 3.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KND94299.1 - 0.00031 20.5 1.8 0.00053 19.8 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND94299.1 - 0.0037 17.3 4.6 0.0083 16.1 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KND94299.1 - 0.0079 16.2 1.4 0.021 14.9 1.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 KND94299.1 - 0.061 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_4 PF14570.6 KND94299.1 - 0.077 12.8 2.9 0.14 12.0 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HC5HC2H PF13771.6 KND94299.1 - 0.17 12.2 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 KND94299.1 - 0.37 10.7 2.5 0.58 10.1 1.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KND94299.1 - 0.52 10.3 3.0 1 9.3 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 KND94299.1 - 2.2 8.4 4.9 4.5 7.4 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 KND94299.1 - 5.3 7.3 6.5 13 6.1 4.2 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain CAP_GLY PF01302.25 KND94300.1 - 6.2e-22 77.4 3.3 9.6e-22 76.8 3.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KND94300.1 - 7.4e-20 71.2 0.0 1.1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KND94300.1 - 4.3e-06 26.4 0.0 8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 KND94301.1 - 1e-13 51.2 3.3 7.5e-11 42.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND94301.1 - 5.5e-05 23.3 3.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.12 KND94302.1 - 2.4e-11 44.1 0.0 3.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND94302.1 - 1.3e-09 38.6 0.0 2.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND94302.1 - 0.00012 22.7 0.0 0.00026 21.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND94302.1 - 0.00068 19.5 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND94302.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DS PF01916.17 KND94303.1 - 2.3e-126 420.9 0.0 2.6e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RabGAP-TBC PF00566.18 KND94304.1 - 1.7e-48 165.1 0.0 2.6e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 KND94304.1 - 0.01 16.2 0.0 0.036 14.4 0.0 1.9 1 1 1 2 2 2 0 Porphobilinogen deaminase, C-terminal domain Filament PF00038.21 KND94305.1 - 0.062 12.9 0.4 0.095 12.3 0.4 1.2 1 0 0 1 1 1 0 Intermediate filament protein Pkinase PF00069.25 KND94306.1 - 1.8e-49 168.5 0.2 3.2e-33 115.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND94306.1 - 3.5e-22 78.9 0.6 5.9e-20 71.6 0.6 3.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND94306.1 - 5.8e-05 22.5 0.0 0.00018 20.9 0.0 1.7 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 KND94306.1 - 0.0066 16.4 0.1 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glycos_transf_1 PF00534.20 KND94307.1 - 1.7e-32 112.4 0.0 2.6e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KND94307.1 - 1.2e-14 54.9 0.0 2.6e-14 53.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KND94307.1 - 5.6e-13 49.2 2.5 1.4e-12 48.0 2.5 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 KND94307.1 - 2.8e-06 27.9 10.7 2.8e-06 27.9 10.7 2.5 3 0 0 3 3 3 2 Glycosyl transferase 4-like domain tRNA-synt_1c PF00749.21 KND94308.1 - 7.4e-93 310.9 0.0 1e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KND94308.1 - 2e-35 122.2 0.0 3.6e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KND94308.1 - 3.7e-06 26.9 0.0 9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND94308.1 - 2.2e-05 24.5 0.0 9.2e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND94308.1 - 0.00012 22.2 0.1 0.00028 21.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pentapeptide_4 PF13599.6 KND94308.1 - 0.077 13.2 0.9 1.7 8.9 0.1 2.9 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) DUF3836 PF12930.7 KND94309.1 - 0.079 12.7 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Ank_2 PF12796.7 KND94310.1 - 1.5e-81 269.0 0.0 8.6e-15 55.1 0.0 7.9 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND94310.1 - 7.8e-64 211.3 0.5 1.3e-08 35.2 0.0 11.5 5 3 6 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KND94310.1 - 7e-62 203.3 4.6 0.00032 21.0 0.1 14.9 15 1 0 15 15 15 12 Ankyrin repeat Ank_3 PF13606.6 KND94310.1 - 6.5e-60 192.0 0.0 0.00018 21.7 0.0 15.6 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 KND94310.1 - 4.7e-51 170.2 3.1 5.9e-06 26.5 0.0 10.7 4 3 8 12 12 12 10 Ankyrin repeats (many copies) GATase_7 PF13537.6 KND94310.1 - 0.032 14.1 0.0 78 3.2 0.0 5.3 6 1 0 7 7 7 0 Glutamine amidotransferase domain VWA_3_C PF18571.1 KND94310.1 - 0.93 9.4 12.9 1.6 8.7 0.4 5.8 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain Beta-lactamase PF00144.24 KND94311.1 - 5.2e-40 137.7 0.2 7.1e-40 137.2 0.2 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 KND94311.1 - 1.4e-05 25.5 0.1 2.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) ANAPC4_WD40 PF12894.7 KND94312.1 - 9.7e-09 35.4 0.5 0.062 13.6 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KND94312.1 - 0.00073 20.3 15.8 0.0043 17.9 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Glyco_hydro_18 PF00704.28 KND94314.1 - 1.2e-90 304.5 1.7 1.4e-90 304.2 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PPTA PF01239.22 KND94315.1 - 1e-36 123.6 14.3 2.7e-07 30.1 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Calc_CGRP_IAPP PF00214.19 KND94316.1 - 0.0037 17.6 0.0 0.0076 16.6 0.0 1.5 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family JmjC PF02373.22 KND94317.1 - 1.7e-09 38.1 0.0 5.4e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 KND94317.1 - 5.6e-06 26.5 14.9 5.6e-06 26.5 14.9 2.7 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 KND94317.1 - 0.026 14.2 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 KND94318.1 - 7.2e-39 133.6 20.7 9.4e-39 133.2 20.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 KND94319.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 KND94320.1 - 1.4e-28 98.6 0.7 3.5e-28 97.2 0.7 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) DUF3696 PF12476.8 KND94321.1 - 0.17 12.3 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) rRNA_proc-arch PF13234.6 KND94323.1 - 4.2e-85 286.0 0.0 9.8e-85 284.7 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KND94323.1 - 2.7e-50 170.2 1.4 7.8e-50 168.7 1.4 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KND94323.1 - 3e-18 66.2 0.0 8.9e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94323.1 - 6.5e-07 29.7 0.1 2.7e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND94323.1 - 8.3e-05 22.7 0.0 0.0003 20.8 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KND94323.1 - 0.02 14.0 0.0 0.044 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KND94323.1 - 0.051 13.8 0.0 0.25 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain TPR_6 PF13174.6 KND94323.1 - 0.058 14.1 0.0 0.24 12.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 KND94323.1 - 6.1 5.3 17.4 0.014 14.0 7.3 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) APH PF01636.23 KND94324.1 - 2.7e-11 43.9 0.1 6e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 KND94324.1 - 0.0014 18.8 5.1 0.0023 18.1 5.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Glyco_hydro_65m PF03632.15 KND94325.1 - 1.1e-26 93.6 4.1 1.2e-22 80.3 0.4 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 KND94325.1 - 1.3e-23 83.8 0.0 2.2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain UCR_TM PF02921.14 KND94326.1 - 0.017 15.6 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Period_C PF12114.8 KND94326.1 - 0.2 11.2 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FAD_binding_4 PF01565.23 KND94327.1 - 3e-23 82.1 0.5 4.7e-23 81.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KND94327.1 - 0.011 15.8 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like DUF2407_C PF13373.6 KND94328.1 - 4.4e-30 104.7 0.0 6.1e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 KND94328.1 - 3.1e-29 101.6 0.0 4.5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KND94328.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF4589 PF15252.6 KND94328.1 - 0.015 15.3 0.2 0.022 14.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Ima1_N PF09779.9 KND94329.1 - 3e-35 122.0 4.4 6.6e-35 120.9 4.4 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KND94329.1 - 0.014 15.4 3.4 0.49 10.5 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon Casein_kappa PF00997.18 KND94329.1 - 0.021 14.9 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 Kappa casein MFS_1 PF07690.16 KND94330.1 - 1.6e-28 99.7 56.2 2.5e-22 79.3 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KND94330.1 - 0.014 14.7 28.7 0.038 13.3 28.7 1.6 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB Acyl-CoA_dh_1 PF00441.24 KND94331.1 - 1e-29 103.7 4.1 1.6e-29 103.0 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KND94331.1 - 1.9e-14 53.6 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KND94331.1 - 0.00068 19.9 1.8 0.0014 18.9 1.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KND94331.1 - 0.19 11.4 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acetyltransf_1 PF00583.25 KND94332.1 - 7.3e-13 48.8 0.0 9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND94332.1 - 2.9e-11 43.4 0.0 3.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND94332.1 - 1.6e-07 31.6 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KND94332.1 - 0.00089 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 KND94332.1 - 0.016 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 KND94332.1 - 0.03 15.0 0.0 0.04 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KND94332.1 - 0.097 12.8 0.0 0.52 10.4 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FMO-like PF00743.19 KND94334.1 - 3.9e-32 111.4 0.0 2.2e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KND94334.1 - 4.1e-11 42.7 0.3 2.9e-07 30.0 0.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KND94334.1 - 1.4e-08 34.3 0.0 1.2e-06 28.0 0.0 2.9 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND94334.1 - 9.2e-08 31.6 0.0 1.1e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KND94334.1 - 0.0024 18.1 0.0 0.0065 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND94334.1 - 0.0039 16.8 0.4 0.28 10.7 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND94334.1 - 0.0056 16.7 0.0 0.053 13.5 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KND94334.1 - 0.23 10.6 0.2 0.37 10.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain PHO4 PF01384.20 KND94335.1 - 1.3e-113 379.5 16.7 1.5e-113 379.3 16.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family P21-Arc PF04062.14 KND94336.1 - 2.3e-71 239.4 0.0 2.9e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 KND94337.1 - 9.7e-127 422.2 0.0 1.1e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Gcd10p family FlxA PF14282.6 KND94339.1 - 0.048 13.6 20.9 0.77 9.8 15.4 2.8 2 1 0 2 2 2 0 FlxA-like protein GrpE PF01025.19 KND94339.1 - 0.11 12.1 16.7 0.048 13.3 9.8 2.8 1 1 2 3 3 3 0 GrpE Metal_hydrol PF10118.9 KND94339.1 - 0.13 12.0 1.3 0.2 11.3 1.3 1.2 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase LMBR1 PF04791.16 KND94339.1 - 3.8 6.3 6.6 5 5.9 6.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prefoldin_2 PF01920.20 KND94340.1 - 1.6e-24 85.9 12.1 2.4e-24 85.3 12.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF1640 PF07798.11 KND94340.1 - 0.07 13.2 7.8 0.3 11.1 7.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Prominin PF05478.11 KND94340.1 - 0.071 11.1 3.3 0.072 11.1 3.3 1.1 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 KND94340.1 - 0.14 12.7 8.1 1.9 9.1 0.9 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal THOC7 PF05615.13 KND94340.1 - 1.6 9.0 12.8 3.1 8.1 12.8 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 AAA_23 PF13476.6 KND94340.1 - 3.2 8.2 11.9 4.3 7.8 11.9 1.2 1 0 0 1 1 1 0 AAA domain Ntox1 PF15500.6 KND94340.1 - 6.7 7.1 6.8 1.8e+02 2.6 6.0 2.3 1 1 0 1 1 1 0 Putative RNase-like toxin, toxin_1 2OG-FeII_Oxy_3 PF13640.6 KND94341.1 - 7.1e-10 39.6 0.0 1.2e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 KND94342.1 - 9.8e-14 51.7 0.0 3.5e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 KND94342.1 - 3.4e-09 36.6 0.0 1.4e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Baculo_LEF-11 PF06385.12 KND94342.1 - 0.14 12.6 0.0 1.7 9.2 0.0 2.2 1 1 0 1 1 1 0 Baculovirus LEF-11 protein Band_7 PF01145.25 KND94343.1 - 7.5e-28 97.7 2.8 1.2e-27 97.1 2.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 KND94343.1 - 0.0099 15.6 0.2 0.016 15.0 0.2 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family ANAPC10 PF03256.16 KND94344.1 - 2e-48 164.5 0.0 3.2e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Cwf_Cwc_15 PF04889.12 KND94344.1 - 0.27 10.9 7.9 0.39 10.4 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 KND94344.1 - 2 7.9 6.2 2.8 7.5 6.2 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 KND94344.1 - 5.2 5.0 8.7 6.9 4.6 8.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Asp PF00026.23 KND94345.1 - 8.5e-53 179.8 0.0 1e-52 179.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KND94345.1 - 2.2e-12 47.5 1.0 8.4e-10 39.2 0.0 3.8 3 2 1 4 4 4 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KND94345.1 - 9.7e-06 25.4 0.0 2.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KND94345.1 - 0.025 15.2 0.1 21 5.8 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KND94345.1 - 0.078 13.5 0.1 29 5.3 0.0 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease HSP70 PF00012.20 KND94346.1 - 1.5e-55 188.6 23.0 1.3e-51 175.5 2.3 3.5 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 KND94346.1 - 0.0099 14.7 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Allexi_40kDa PF05549.11 KND94346.1 - 0.051 13.1 1.7 0.55 9.7 0.0 2.8 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3484 PF11983.8 KND94346.1 - 2.4 9.3 7.6 4.9 8.3 0.0 3.9 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Fringe PF02434.16 KND94347.1 - 0.0042 16.5 5.9 0.0079 15.7 2.9 2.6 2 1 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 KND94347.1 - 0.097 12.5 0.1 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 Galactosyltransferase Glyco_tranf_2_4 PF13704.6 KND94347.1 - 0.11 13.0 2.0 0.13 12.8 0.2 2.1 2 1 0 2 2 2 0 Glycosyl transferase family 2 MscS_porin PF12795.7 KND94348.1 - 0.0036 16.9 3.0 0.0045 16.6 3.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain SKA1 PF07160.12 KND94348.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Tropomyosin PF00261.20 KND94348.1 - 0.021 14.2 0.7 0.025 14.0 0.7 1.1 1 0 0 1 1 1 0 Tropomyosin Csm1_N PF18504.1 KND94348.1 - 0.034 14.5 1.3 0.05 14.0 1.3 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain GreA_GreB_N PF03449.15 KND94348.1 - 0.046 13.9 1.5 0.073 13.2 0.7 1.7 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Fib_alpha PF08702.10 KND94348.1 - 0.056 13.6 0.3 0.077 13.2 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 KND94348.1 - 0.057 13.5 0.1 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 EzrA PF06160.12 KND94348.1 - 0.068 11.3 0.1 0.075 11.2 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Herpes_UL6 PF01763.16 KND94348.1 - 0.088 11.3 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like XhlA PF10779.9 KND94348.1 - 0.11 12.7 1.2 0.17 12.1 1.2 1.2 1 0 0 1 1 1 0 Haemolysin XhlA DUF4446 PF14584.6 KND94348.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SlyX PF04102.12 KND94348.1 - 0.16 12.6 5.3 0.41 11.3 5.3 1.7 1 1 0 1 1 1 0 SlyX UNC45-central PF11701.8 KND94349.1 - 1.2e-54 184.5 0.0 8.4e-54 181.7 0.0 2.5 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.23 KND94349.1 - 0.0024 17.8 10.1 0.13 12.3 0.0 6.0 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KND94349.1 - 1 9.8 7.7 99 3.6 0.1 5.8 6 0 0 6 6 6 0 HEAT repeat Fungal_trans PF04082.18 KND94350.1 - 5.7e-13 48.5 0.3 1.8e-12 46.9 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94350.1 - 3.3e-07 30.3 12.7 6.2e-07 29.4 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 KND94350.1 - 1.2 9.0 9.2 1.8 8.5 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 KND94350.1 - 6.8 7.3 16.3 15 6.2 16.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Steroid_dh PF02544.16 KND94353.1 - 6.9e-27 94.3 0.4 1e-26 93.8 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KND94353.1 - 6.3e-05 22.6 0.7 9.3e-05 22.0 0.2 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) Diphthamide_syn PF01866.17 KND94354.1 - 9.5e-115 383.2 0.0 1.4e-114 382.6 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Aldose_epim PF01263.20 KND94354.1 - 1.7e-46 158.9 0.0 3.1e-46 158.1 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase HMGL-like PF00682.19 KND94355.1 - 9.6e-43 146.6 0.1 1.1e-41 143.1 0.1 1.9 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.25 KND94356.1 - 2.6e-65 220.0 0.0 4.1e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KND94356.1 - 2.6e-14 53.5 0.9 5.2e-14 52.5 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KND94356.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Mesothelin PF06060.12 KND94356.1 - 0.15 10.3 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) DUF913 PF06025.12 KND94357.1 - 1.8e-132 441.8 0.0 1.8e-132 441.8 0.0 6.2 8 1 0 8 8 8 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 KND94357.1 - 1.5e-128 429.2 0.0 1.5e-128 429.2 0.0 3.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.25 KND94357.1 - 5.3e-94 315.2 0.1 9.1e-94 314.4 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KND94357.1 - 4.4e-20 70.4 27.1 2.8e-08 32.9 0.3 4.2 4 0 0 4 4 4 3 Ubiquitin binding region DUF3385 PF11865.8 KND94357.1 - 0.29 11.0 9.5 28 4.6 0.0 5.9 6 1 0 7 7 7 0 Domain of unknown function (DUF3385) RabGAP-TBC PF00566.18 KND94359.1 - 6.2e-48 163.3 0.0 8.6e-47 159.6 0.0 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KASH_CCD PF14662.6 KND94359.1 - 0.00051 19.9 27.6 0.00088 19.2 26.6 2.1 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 KND94359.1 - 0.0034 17.6 19.2 0.0034 17.6 19.2 2.9 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 Cnn_1N PF07989.11 KND94359.1 - 0.013 15.6 23.6 0.026 14.7 6.2 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 KND94359.1 - 0.092 13.0 23.3 0.11 12.7 0.3 4.1 5 0 0 5 5 5 0 Homeobox associated leucine zipper YabA PF06156.13 KND94359.1 - 2.2 9.0 23.0 0.07 13.8 3.7 3.5 2 1 1 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 KND94359.1 - 4.9 7.3 21.5 3.1 8.0 3.7 3.8 2 1 1 3 3 3 0 bZIP transcription factor Mod_r PF07200.13 KND94359.1 - 5.5 7.1 26.7 0.64 10.1 11.2 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 KND94359.1 - 9.9 6.6 15.4 4.8 7.7 0.8 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ctf8 PF09696.10 KND94360.1 - 7.1e-41 139.9 0.4 5.3e-40 137.1 0.4 1.9 1 1 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.19 KND94361.1 - 4e-57 191.6 0.0 8.2e-57 190.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 KND94361.1 - 0.95 8.5 6.9 1.2 8.2 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pribosyl_synth PF14572.6 KND94362.1 - 8.4e-43 146.5 0.5 1.1e-36 126.6 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KND94362.1 - 2.1e-30 105.0 0.0 4.6e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KND94362.1 - 2.6e-13 49.8 0.1 4.4e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PARP PF00644.20 KND94363.1 - 4.9e-10 39.3 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KND94363.1 - 5.4e-07 29.3 0.0 1.4e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Opiods_neuropep PF01160.18 KND94363.1 - 0.071 13.2 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide PIG-H PF10181.9 KND94364.1 - 4.2e-26 90.6 0.1 6.1e-26 90.1 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 KND94365.1 - 9.4e-34 116.1 0.0 5.6e-33 113.6 0.0 2.1 2 0 0 2 2 2 1 tRNA pseudouridine synthase RNA_pol_Rpb4 PF03874.16 KND94366.1 - 5.5e-23 81.6 0.0 7.1e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ras PF00071.22 KND94367.1 - 4.3e-17 62.2 0.0 1.4e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 Ras family Arf PF00025.21 KND94367.1 - 0.00018 21.0 0.0 0.036 13.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KND94367.1 - 0.00044 20.5 0.0 0.0022 18.2 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 KND94367.1 - 0.046 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KND94367.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PduV-EutP PF10662.9 KND94367.1 - 0.1 12.3 0.0 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KND94367.1 - 0.12 11.9 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 KND94367.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snf7 PF03357.21 KND94368.1 - 2.8e-19 69.4 2.5 2.8e-19 69.4 2.5 1.9 2 0 0 2 2 2 1 Snf7 GAS PF13851.6 KND94368.1 - 0.057 12.8 1.5 0.12 11.7 1.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KND94368.1 - 4.8 7.2 8.0 0.78 9.8 2.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1263 PF06882.12 KND94369.1 - 0.01 15.9 0.2 0.019 15.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) GDPD PF03009.17 KND94373.1 - 1.1e-69 235.1 0.0 1.9e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 KND94373.1 - 1.1e-23 83.3 2.9 2.3e-07 31.2 0.1 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND94373.1 - 1.5e-23 83.2 0.2 8.9e-14 51.8 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) SPX PF03105.19 KND94373.1 - 2.3e-19 70.6 12.1 8.2e-11 42.4 0.1 4.4 3 2 1 4 4 4 3 SPX domain Ank_5 PF13857.6 KND94373.1 - 1.3e-17 63.6 0.1 2.1e-05 24.7 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND94373.1 - 6.5e-14 50.7 0.7 0.0046 17.4 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 KND94373.1 - 3.8e-12 46.1 1.1 0.019 15.4 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat RebB PF11747.8 KND94373.1 - 0.058 13.5 0.1 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Killing trait adh_short_C2 PF13561.6 KND94374.1 - 5.3e-59 199.6 3.9 6.5e-59 199.3 3.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND94374.1 - 7.4e-51 172.4 1.5 9.6e-51 172.0 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KND94374.1 - 1.1e-09 38.5 1.8 2.9e-09 37.1 1.8 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND94374.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4448 PF14610.6 KND94375.1 - 0.004 16.9 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 KND94375.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 KND94375.1 - 8.3 5.9 8.3 0.12 11.8 0.7 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_M41 PF01434.18 KND94376.1 - 2.9e-54 183.8 2.0 4.7e-54 183.1 2.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KND94376.1 - 4.7e-42 143.5 0.0 1.2e-41 142.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND94376.1 - 1.9e-07 30.8 0.1 3.7e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KND94376.1 - 1.4e-06 28.3 0.0 3.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND94376.1 - 1.2e-05 25.7 0.1 0.063 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KND94376.1 - 5.1e-05 23.7 2.4 0.00031 21.2 0.6 3.0 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 KND94376.1 - 8e-05 22.0 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KND94376.1 - 0.00037 20.3 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KND94376.1 - 0.0012 19.0 0.0 0.0035 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KND94376.1 - 0.0028 17.2 0.7 1.5 8.3 0.2 3.0 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 KND94376.1 - 0.009 15.8 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KND94376.1 - 0.011 15.2 0.2 0.075 12.5 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KND94376.1 - 0.02 14.3 0.9 0.045 13.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KND94376.1 - 0.046 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KND94376.1 - 0.069 13.3 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RVT_1 PF00078.27 KND94376.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TsaE PF02367.17 KND94376.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KND94376.1 - 0.098 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KND94376.1 - 0.15 12.0 0.6 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KND94376.1 - 0.15 12.5 0.4 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KND94376.1 - 0.16 11.7 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KND94376.1 - 0.2 11.1 0.3 0.48 9.8 0.3 1.5 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.12 KND94376.1 - 0.28 10.5 1.6 0.82 8.9 0.4 2.2 1 1 1 2 2 2 0 Zeta toxin zf-C2H2 PF00096.26 KND94377.1 - 1.1e-20 72.8 29.7 4.7e-06 26.8 0.1 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND94377.1 - 1.6e-18 66.2 28.7 2.1e-06 27.9 0.6 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND94377.1 - 1.6e-09 37.8 26.7 0.011 16.5 1.0 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND94377.1 - 0.00019 21.6 2.7 0.45 10.9 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KND94377.1 - 0.0094 16.2 9.7 0.92 9.8 6.4 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 KND94377.1 - 0.014 15.1 2.0 0.014 15.1 2.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 KND94377.1 - 0.018 15.4 0.6 0.018 15.4 0.6 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 KND94377.1 - 0.023 15.4 2.5 0.023 15.4 2.5 3.4 1 1 2 3 3 3 0 TRAF-type zinc finger Rz1 PF06085.11 KND94377.1 - 1.2 9.0 6.4 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor CHORD PF04968.12 KND94377.1 - 2.4 9.0 14.9 4.9 7.9 0.2 4.3 3 1 1 4 4 4 0 CHORD FOXP-CC PF16159.5 KND94377.1 - 5.7 7.7 18.9 7.2 7.3 0.3 4.9 3 1 2 5 5 5 0 FOXP coiled-coil domain Metallophos PF00149.28 KND94378.1 - 5e-33 115.3 0.0 2.4e-28 100.0 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KND94378.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KND94378.1 - 0.054 14.0 0.1 0.13 12.7 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Met_10 PF02475.16 KND94379.1 - 4.9e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein LIME1 PF15332.6 KND94379.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 EF-hand_6 PF13405.6 KND94380.1 - 7.4e-09 34.8 0.2 0.0017 18.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KND94380.1 - 2e-05 23.9 0.1 0.00058 19.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KND94380.1 - 5.2e-05 23.6 0.1 0.00014 22.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 KND94380.1 - 0.00037 19.8 0.1 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KND94380.1 - 0.15 11.9 0.7 0.46 10.4 0.2 2.1 2 1 0 2 2 2 0 EF-hand domain pair DUF5484 PF17583.2 KND94380.1 - 0.2 11.3 0.8 4.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5484) ORC6 PF05460.13 KND94381.1 - 5.3e-30 104.9 3.0 5.3e-30 104.9 3.0 1.8 2 0 0 2 2 2 1 Origin recognition complex subunit 6 (ORC6) Frataxin_Cyay PF01491.16 KND94382.1 - 6e-37 126.0 0.0 7.4e-37 125.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Clat_adaptor_s PF01217.20 KND94383.1 - 8.6e-39 132.7 0.0 3.2e-38 130.8 0.0 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sugar_tr PF00083.24 KND94385.1 - 1.9e-104 350.1 14.9 2.3e-104 349.8 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND94385.1 - 3.9e-25 88.5 50.8 9.4e-24 84.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KND94385.1 - 9.1e-08 31.1 20.4 2.5e-06 26.3 6.6 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KND94385.1 - 0.0057 15.6 2.7 0.0092 14.9 2.7 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TB2_DP1_HVA22 PF03134.19 KND94385.1 - 0.077 12.9 1.6 0.23 11.4 1.6 1.8 1 0 0 1 1 1 0 TB2/DP1, HVA22 family DUF2530 PF10745.9 KND94385.1 - 0.43 10.8 3.9 0.88 9.8 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_3 PF05977.13 KND94385.1 - 0.67 8.3 6.3 0.21 9.9 0.9 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Chs7 PF12271.8 KND94387.1 - 1.5e-102 342.9 7.0 1.9e-102 342.5 7.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2070 PF09843.9 KND94387.1 - 0.33 9.2 13.1 0.15 10.4 10.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) HisKA_7TM PF16927.5 KND94387.1 - 0.56 10.2 19.3 0.82 9.7 19.3 1.2 1 0 0 1 1 1 0 N-terminal 7TM region of histidine kinase Glyoxalase PF00903.25 KND94389.1 - 6.8e-21 74.8 0.0 4.5e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KND94389.1 - 3.5e-10 40.1 0.1 0.00071 19.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KND94389.1 - 0.0012 19.0 0.0 0.071 13.2 0.0 2.8 3 0 0 3 3 3 1 Glyoxalase-like domain Ssl1 PF04056.14 KND94390.1 - 7.8e-74 247.7 0.0 1e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 KND94390.1 - 9.6e-18 64.2 9.7 9.6e-18 64.2 9.7 2.5 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 KND94390.1 - 8.6e-17 61.7 0.0 3.1e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KND94390.1 - 0.00021 21.6 0.0 0.00029 21.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain PolyA_pol_arg_C PF12626.7 KND94391.1 - 0.0062 16.6 2.7 0.0094 16.0 2.7 1.2 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus tRNA-synt_1 PF00133.22 KND94392.1 - 4.1e-34 117.8 0.0 8.6e-25 87.0 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KND94392.1 - 6.7e-14 51.4 0.2 1.5e-08 33.9 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KND94392.1 - 9.4e-12 45.1 0.2 1.9e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KND94392.1 - 7.4e-07 28.8 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Herpes_UL49_5 PF05702.11 KND94392.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein MC1 PF05854.11 KND94392.1 - 0.55 10.6 3.3 7.7 6.9 0.1 3.4 3 0 0 3 3 3 0 Non-histone chromosomal protein MC1 Q_salvage PF10343.9 KND94393.1 - 3.4e-119 397.6 0.0 5.9e-119 396.8 0.0 1.4 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family DNA_pol_delta_4 PF04081.13 KND94394.1 - 6e-43 146.3 1.7 7.5e-43 146.0 1.7 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 NYD-SP28 PF14772.6 KND94394.1 - 0.0023 18.0 1.9 0.0023 18.0 1.9 1.7 2 0 0 2 2 2 1 Sperm tail adh_short_C2 PF13561.6 KND94395.1 - 5.7e-21 75.2 0.0 8.9e-21 74.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND94395.1 - 1.5e-12 47.4 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ThiF PF00899.21 KND94396.1 - 5.6e-71 238.7 0.0 1.1e-70 237.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KND94396.1 - 1.9e-23 82.8 1.4 2.4e-23 82.5 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KND94396.1 - 5.2e-07 29.9 1.3 0.0001 22.4 0.1 2.7 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KND94396.1 - 0.00088 19.7 0.1 0.0023 18.3 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KND94396.1 - 0.019 15.0 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KND94396.1 - 0.055 13.7 0.9 0.31 11.3 0.9 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 KND94396.1 - 0.075 13.6 0.6 0.6 10.7 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.21 KND94397.1 - 8.1e-20 71.0 3.2 2.7e-19 69.3 3.2 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KND94397.1 - 0.00064 19.5 4.0 0.00064 19.5 4.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily DUF4383 PF14325.6 KND94397.1 - 0.0095 16.2 1.5 1.3 9.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4383) adh_short PF00106.25 KND94398.1 - 1.4e-10 41.0 0.0 2.3e-05 24.0 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KND94398.1 - 4.2e-09 36.3 0.1 0.00022 20.9 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KND94398.1 - 8.9e-05 22.1 0.0 0.00022 20.8 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KND94398.1 - 0.0011 18.9 0.1 0.014 15.3 0.1 2.3 2 1 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KND94398.1 - 0.003 17.4 0.1 0.0043 17.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KND94398.1 - 0.085 13.3 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KND94398.1 - 0.097 12.0 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 KND94398.1 - 0.1 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Ank_4 PF13637.6 KND94399.1 - 2e-15 56.9 1.2 7.1e-05 23.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KND94399.1 - 2.4e-14 53.7 0.0 3.6e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KND94399.1 - 2.6e-14 51.9 0.2 0.0046 17.4 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 KND94399.1 - 1.4e-08 34.8 1.2 0.032 14.5 0.0 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KND94399.1 - 1.4e-07 31.6 3.2 0.011 16.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat PTR2 PF00854.21 KND94400.1 - 3.9e-87 292.6 6.4 7.1e-87 291.8 6.0 1.6 1 1 0 1 1 1 1 POT family Septin PF00735.18 KND94401.1 - 1.9e-113 378.4 0.3 2.2e-113 378.2 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KND94401.1 - 1.6e-07 31.4 0.0 3.1e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND94401.1 - 1.8e-06 28.0 0.1 0.00022 21.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KND94401.1 - 4.2e-06 26.3 0.0 8.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KND94401.1 - 1.7e-05 24.5 0.5 0.012 15.2 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KND94401.1 - 0.0013 18.8 0.3 1.8 8.6 0.1 2.6 1 1 0 2 2 2 2 Dynamin family NB-ARC PF00931.22 KND94401.1 - 0.0034 16.6 0.1 0.0058 15.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 KND94401.1 - 0.0045 16.5 0.1 0.034 13.7 0.0 2.3 2 1 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 KND94401.1 - 0.0049 17.3 0.1 0.028 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 KND94401.1 - 0.0075 15.6 0.1 0.35 10.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 KND94401.1 - 0.0078 16.5 0.1 0.022 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KND94401.1 - 0.0092 16.5 0.2 0.016 15.7 0.2 1.7 1 1 0 1 1 1 1 ABC transporter Microtub_bd PF16796.5 KND94401.1 - 0.06 13.3 0.2 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Microtubule binding G-alpha PF00503.20 KND94401.1 - 0.081 12.1 0.7 0.3 10.2 0.7 1.9 1 1 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KND94401.1 - 0.081 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1542 PF07564.11 KND94401.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) AAA_29 PF13555.6 KND94401.1 - 0.14 12.0 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 KND94401.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TRF PF08558.10 KND94402.1 - 2e-18 66.9 0.0 3.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 KND94402.1 - 1.7e-05 24.9 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND94402.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fic PF02661.18 KND94403.1 - 3e-18 66.5 0.0 8.2e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family Bromodomain PF00439.25 KND94404.1 - 3.6e-05 23.7 0.0 0.00013 22.0 0.0 1.9 1 1 0 1 1 1 1 Bromodomain Myelin-PO_C PF10570.9 KND94404.1 - 0.12 12.8 0.1 0.3 11.6 0.1 1.7 1 0 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region PIGA PF08288.12 KND94405.1 - 6.1e-46 154.9 1.4 6.1e-46 154.9 1.4 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 KND94405.1 - 4e-27 94.8 0.0 6.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KND94405.1 - 7e-27 94.5 0.6 1.1e-26 93.9 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KND94405.1 - 9.5e-23 81.1 0.0 2e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KND94405.1 - 5.2e-12 46.5 0.0 8e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KND94405.1 - 3.5e-05 23.8 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KND94405.1 - 0.0015 18.9 0.0 0.0049 17.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Rgp1 PF08737.10 KND94406.1 - 2e-155 518.1 0.0 5.2e-155 516.7 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.29 KND94406.1 - 0.0052 16.8 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain WD40 PF00400.32 KND94407.1 - 3.8e-13 49.7 13.8 0.00045 21.0 0.1 7.8 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94407.1 - 3.3e-06 27.3 0.1 0.12 12.7 0.0 5.8 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 KND94409.1 - 2.3e-35 122.0 0.0 6.8e-35 120.4 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94409.1 - 2.3e-22 79.4 0.0 5.4e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KND94409.1 - 3.8e-22 78.3 0.0 6.7e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KND94409.1 - 0.02 14.9 0.1 0.082 12.9 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3984 PF13136.6 KND94410.1 - 2 7.7 21.1 0.59 9.5 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) DUF2244 PF10003.9 KND94410.1 - 2.3 7.9 4.4 0.71 9.5 1.2 1.8 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) PRMT5_TIM PF17285.2 KND94411.1 - 4.2e-68 229.3 0.0 5.6e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KND94411.1 - 4.4e-62 209.0 0.0 7.5e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KND94411.1 - 1.2e-43 149.0 0.0 5.3e-41 140.4 0.0 2.3 1 1 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 KND94411.1 - 0.23 11.2 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CRM1_C PF08767.11 KND94412.1 - 5.9e-123 410.1 4.2 5.9e-123 410.1 4.2 3.7 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 KND94412.1 - 6.6e-41 139.8 13.5 2.2e-40 138.1 8.6 3.9 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KND94412.1 - 9.6e-34 114.8 4.1 3.2e-33 113.2 4.1 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KND94412.1 - 7.9e-28 96.3 4.7 2.3e-27 94.8 0.8 3.4 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KND94412.1 - 1.1e-19 69.6 2.8 3e-19 68.2 2.8 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KND94412.1 - 1.8e-11 43.8 0.0 7.3e-11 41.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KND94412.1 - 0.0016 18.4 1.1 0.88 9.5 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KND94412.1 - 0.0019 17.4 0.4 0.0019 17.4 0.4 2.8 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Hemocyanin_M PF00372.19 KND94412.1 - 0.039 13.1 0.0 0.22 10.6 0.0 2.1 1 1 0 1 1 1 0 Hemocyanin, copper containing domain Ribosomal_L26 PF16906.5 KND94413.1 - 6.9e-37 125.8 3.1 9.4e-37 125.3 3.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KND94413.1 - 1.2e-07 31.4 1.6 3.1e-07 30.1 1.6 1.7 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KND94413.1 - 0.017 15.1 0.2 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GHL5 PF14872.6 KND94413.1 - 0.12 10.4 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Use1 PF09753.9 KND94414.1 - 0.0019 18.0 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 KND94415.1 - 1.9e-22 80.4 1.4 2.1e-20 73.8 1.4 2.6 1 1 0 1 1 1 1 Apc15p protein Tub_N PF16322.5 KND94415.1 - 2.9 8.3 13.9 0.027 14.9 4.3 2.1 2 0 0 2 2 2 0 Tubby N-terminal Na_H_Exchanger PF00999.21 KND94416.1 - 1.3e-48 165.7 19.4 1.9e-48 165.2 19.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KND94416.1 - 0.095 12.8 1.0 0.24 11.5 0.2 2.1 2 0 0 2 2 2 0 YrhC-like protein EthD PF07110.11 KND94418.1 - 5.7e-10 40.2 1.7 9.7e-10 39.5 1.6 1.4 1 1 0 1 1 1 1 EthD domain DUF1918 PF08940.11 KND94418.1 - 0.053 13.1 0.8 2.2 8.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) MmlI PF09448.10 KND94418.1 - 0.11 12.9 2.1 0.5 10.8 2.1 1.9 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Ank_5 PF13857.6 KND94419.1 - 5.1e-13 49.0 1.1 3.9e-10 39.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KND94419.1 - 1.5e-12 47.3 1.4 2.7e-05 24.4 0.6 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KND94419.1 - 8e-11 42.4 0.1 1.5e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND94419.1 - 5.8e-10 39.5 0.2 1.5e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TIG PF01833.24 KND94419.1 - 2e-09 37.4 0.0 6.7e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_3 PF13606.6 KND94419.1 - 2.2e-08 33.7 0.5 0.014 15.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Velvet PF11754.8 KND94420.1 - 2.1e-54 185.1 1.5 9.2e-34 117.5 0.0 3.2 2 1 1 3 3 3 2 Velvet factor Arm PF00514.23 KND94421.1 - 1.4e-06 28.1 0.8 0.011 15.7 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KND94421.1 - 0.0015 18.6 11.3 0.79 10.1 0.1 7.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 KND94421.1 - 0.0089 16.5 13.5 3.1 8.4 0.1 6.1 6 0 0 6 6 6 2 HEAT-like repeat PUL PF08324.11 KND94421.1 - 0.016 14.5 0.1 0.93 8.7 0.0 2.5 2 0 0 2 2 2 0 PUL domain V-ATPase_H_C PF11698.8 KND94421.1 - 0.061 13.4 0.7 5.5 7.1 0.1 3.3 2 1 1 3 3 3 0 V-ATPase subunit H DUF747 PF05346.11 KND94421.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family Cyclin PF08613.11 KND94422.1 - 3.7e-30 105.4 0.0 6.8e-30 104.6 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KND94422.1 - 0.0029 17.3 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPX PF03105.19 KND94422.1 - 0.34 10.8 3.5 0.45 10.4 3.5 1.3 1 0 0 1 1 1 0 SPX domain DUF2556 PF10831.8 KND94423.1 - 0.28 11.2 0.7 0.46 10.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) Het-C PF07217.11 KND94424.1 - 4.4e-280 930.1 0.0 5.3e-280 929.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.21 KND94425.1 - 3.4e-39 135.0 0.0 1.1e-32 113.8 0.0 2.5 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 KND94425.1 - 0.00065 19.4 0.0 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Metallophos PF00149.28 KND94427.1 - 4e-09 37.3 2.0 9.7e-09 36.0 2.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND94427.1 - 2.4e-05 24.6 0.1 0.00023 21.4 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CtsR_C PF17727.1 KND94428.1 - 0.034 14.3 0.4 0.089 12.9 0.4 1.6 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain MREG PF15812.5 KND94428.1 - 0.13 12.6 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 Melanoregulin VWA PF00092.28 KND94429.1 - 0.033 14.4 0.0 0.094 13.0 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Cyt-b5 PF00173.28 KND94430.1 - 1.3e-17 63.7 1.0 2.5e-17 62.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KND94430.1 - 5.2e-12 46.3 18.8 5.2e-12 46.3 18.8 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KND94430.1 - 0.033 14.4 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region COX14 PF14880.6 KND94430.1 - 0.18 11.7 1.7 0.43 10.5 0.4 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RRM_1 PF00076.22 KND94431.1 - 3.9e-41 138.7 2.8 1.8e-18 66.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KND94431.1 - 1.1e-22 80.9 0.2 3.4e-22 79.3 0.2 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KND94431.1 - 0.00035 20.4 0.0 5 7.1 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KND94431.1 - 0.046 13.7 0.0 3 7.9 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KND94431.1 - 0.05 13.6 1.1 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif RRM_7 PF16367.5 KND94431.1 - 0.094 12.8 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Aminotran_1_2 PF00155.21 KND94432.1 - 7.1e-34 117.5 0.0 9.4e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DLH PF01738.18 KND94434.1 - 1e-21 77.5 0.0 1.4e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KND94434.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MS_channel PF00924.18 KND94435.1 - 1.8e-18 66.8 2.1 2.5e-18 66.4 2.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel Mito_carr PF00153.27 KND94436.1 - 4.7e-30 103.4 4.4 5.5e-13 48.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KND94437.1 - 6.6e-06 26.8 10.7 1.9 9.5 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Abp2 PF09441.10 KND94438.1 - 3.7e-79 264.7 0.0 5.6e-79 264.1 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 PRIMA1 PF16101.5 KND94438.1 - 3.8 7.6 9.4 11 6.1 9.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KND94438.1 - 9 6.3 8.9 8.3 6.4 7.2 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Sugar_tr PF00083.24 KND94440.1 - 3.8e-88 296.3 17.9 4.7e-88 296.0 17.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND94440.1 - 2.7e-10 39.7 44.1 2.4e-07 30.0 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 KND94441.1 - 1.8e-30 106.3 0.0 2.7e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KND94441.1 - 1.1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KND94441.1 - 0.00077 19.0 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KND94441.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KND94441.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KND94441.1 - 0.2 11.0 0.0 0.28 10.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sds3 PF08598.11 KND94442.1 - 1.6e-22 80.6 7.7 1.6e-22 80.6 7.7 1.4 1 1 0 1 1 1 1 Sds3-like Cpn60_TCP1 PF00118.24 KND94444.1 - 1.5e-169 564.8 1.0 1.7e-169 564.6 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 KND94444.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 KND94445.1 - 2.5e-37 127.7 7.5 2.5e-37 127.7 7.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 KND94445.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic Peptidase_S49_N PF08496.10 KND94445.1 - 4 7.5 5.8 5.7 7.0 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.14 KND94445.1 - 7.6 4.7 7.5 9 4.5 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_1 PF00300.22 KND94446.1 - 1.3e-28 100.0 0.1 5.7e-28 97.9 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) HATPase_c PF02518.26 KND94447.1 - 4.9e-26 91.4 0.3 1.2e-25 90.2 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KND94447.1 - 1.2e-21 76.8 0.3 3.7e-12 46.4 0.2 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 KND94447.1 - 8e-21 74.3 0.2 2.6e-20 72.7 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KND94447.1 - 1.1e-19 70.3 0.4 4.1e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KND94447.1 - 4.4e-06 26.9 0.0 0.0001 22.5 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 KND94447.1 - 5.5e-06 26.6 0.0 0.56 10.5 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KND94447.1 - 1.8e-05 24.7 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KND94447.1 - 0.0082 16.2 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain CPT PF07931.12 KND94447.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UvrA_inter PF17760.1 KND94447.1 - 2.9 8.0 7.8 0.14 12.2 0.5 2.5 4 0 0 4 4 4 0 UvrA interaction domain Sec6 PF06046.13 KND94448.1 - 2.6e-166 554.4 10.6 4.1e-166 553.7 10.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 KND94448.1 - 0.00019 20.5 2.4 0.00029 19.9 0.3 2.3 2 0 0 2 2 2 1 Vps53-like, N-terminal FAD_binding_2 PF00890.24 KND94448.1 - 0.0011 18.1 0.5 0.0034 16.5 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain OmdA PF13376.6 KND94448.1 - 0.13 12.3 5.0 0.15 12.1 0.0 3.2 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF2018 PF09442.10 KND94448.1 - 0.15 13.0 2.4 4.7 8.3 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) KapB PF08810.10 KND94448.1 - 0.48 10.6 3.5 25 5.1 1.0 2.9 2 0 0 2 2 2 0 Kinase associated protein B DUF327 PF03885.13 KND94448.1 - 0.55 10.2 3.8 4.4 7.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Pyr_redox_2 PF07992.14 KND94449.1 - 1.5e-62 211.5 0.2 2e-62 211.1 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KND94449.1 - 1.8e-30 105.4 0.2 5.7e-30 103.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KND94449.1 - 1.9e-20 73.2 1.5 3.4e-19 69.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KND94449.1 - 2.2e-13 50.1 1.2 1e-12 47.9 1.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND94449.1 - 0.00016 20.9 0.0 0.002 17.3 0.0 2.0 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KND94449.1 - 0.0061 15.9 0.7 0.6 9.4 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KND94449.1 - 0.01 14.6 3.1 0.2 10.3 0.1 2.8 2 1 1 3 3 3 0 HI0933-like protein Thi4 PF01946.17 KND94449.1 - 0.012 14.8 0.4 0.029 13.6 0.4 1.6 1 0 0 1 1 1 0 Thi4 family Ntox47 PF15540.6 KND94449.1 - 0.05 13.9 1.6 0.095 13.0 0.0 2.3 3 0 0 3 3 3 0 Bacterial toxin 47 3HCDH_N PF02737.18 KND94449.1 - 0.055 13.3 0.0 0.055 13.3 0.0 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KND94449.1 - 0.22 10.7 1.2 11 5.2 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KND94449.1 - 1.6 8.2 6.3 3.2 7.2 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KND94449.1 - 5.1 6.4 5.9 0.7 9.2 0.1 2.5 3 1 1 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ecl1 PF12855.7 KND94450.1 - 8e-18 66.2 22.1 9.7e-18 65.9 22.1 1.0 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Metallothio_Pro PF02069.16 KND94450.1 - 0.022 15.0 2.0 0.045 14.0 2.0 1.5 1 0 0 1 1 1 0 Prokaryotic metallothionein PLATZ PF04640.14 KND94450.1 - 0.046 14.3 2.5 0.08 13.6 1.1 1.9 2 0 0 2 2 2 0 PLATZ transcription factor DUF2116 PF09889.9 KND94450.1 - 0.34 10.9 1.8 0.62 10.1 0.9 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Allantoicase PF03561.15 KND94452.1 - 5.2e-93 308.6 0.1 5.3e-46 156.2 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Aldo_ket_red PF00248.21 KND94453.1 - 1.6e-39 135.9 0.0 3.4e-38 131.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 KND94454.1 - 8.1e-128 427.1 0.0 1e-127 426.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family XRCC4 PF06632.12 KND94456.1 - 1.4e-08 33.9 16.2 3.1e-08 32.9 16.2 1.5 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Blt1 PF12754.7 KND94457.1 - 8e-39 133.4 0.9 8e-39 133.4 0.9 1.6 2 0 0 2 2 2 1 Blt1 N-terminal domain Blt1_C PF17183.4 KND94457.1 - 5.1e-17 61.2 0.3 9.4e-17 60.4 0.3 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 KND94457.1 - 6.8e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Methyltr_RsmB-F PF01189.17 KND94458.1 - 3.2e-77 258.7 0.0 4.7e-77 258.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KND94458.1 - 6.1e-08 33.1 0.0 1.7e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Toprim_Crpt PF13342.6 KND94458.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Methyltransf_25 PF13649.6 KND94458.1 - 0.03 15.0 0.0 0.077 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 KND94458.1 - 0.041 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) FtsJ PF01728.19 KND94458.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 KND94458.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KND94458.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Prominin PF05478.11 KND94459.1 - 0.0012 16.9 0.2 0.0015 16.6 0.2 1.1 1 0 0 1 1 1 1 Prominin CorA PF01544.18 KND94459.1 - 0.033 13.5 1.7 0.049 12.9 1.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF148 PF02520.17 KND94459.1 - 2.5 8.2 7.4 1.6 8.8 1.6 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF148 Cpn60_TCP1 PF00118.24 KND94460.1 - 9.4e-88 295.0 10.7 2.1e-87 293.9 10.7 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 KND94460.1 - 4.4e-36 123.3 0.2 9.4e-36 122.3 0.2 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4805 PF16063.5 KND94462.1 - 0.018 14.4 0.4 0.02 14.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Alpha_GJ PF03229.13 KND94462.1 - 0.63 10.6 3.5 0.76 10.3 3.1 1.4 1 1 0 1 1 1 0 Alphavirus glycoprotein J Pox_Ag35 PF03286.14 KND94462.1 - 4.4 7.0 15.3 2.9 7.6 13.2 1.6 1 1 1 2 2 2 0 Pox virus Ag35 surface protein tRNA_U5-meth_tr PF05958.11 KND94463.1 - 4e-12 45.8 0.0 1.3e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KND94463.1 - 3.2e-07 30.1 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TRAM PF01938.20 KND94463.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_25 PF13649.6 KND94463.1 - 0.00022 21.9 0.0 0.00047 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND94463.1 - 0.00023 21.0 0.1 0.00041 20.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND94463.1 - 0.095 13.4 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain G_glu_transpept PF01019.21 KND94464.1 - 8.2e-159 529.6 3.2 9.4e-159 529.4 3.2 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Asparaginase_2 PF01112.18 KND94466.1 - 3.6e-41 141.2 7.7 5.5e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 KND94467.1 - 1e-96 323.6 0.0 1.2e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Rogdi_lz PF10259.9 KND94467.1 - 0.0099 15.4 0.9 0.0099 15.4 0.9 1.7 2 0 0 2 2 2 1 Rogdi leucine zipper containing protein ADH_N PF08240.12 KND94468.1 - 4.6e-28 97.3 0.2 7.8e-28 96.5 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND94468.1 - 1.6e-25 89.6 0.3 2.5e-25 89.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND94468.1 - 3e-05 25.1 0.1 4.7e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KND94468.1 - 0.0094 15.3 0.7 0.013 14.8 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KND94468.1 - 0.018 14.4 0.2 0.039 13.3 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 KND94468.1 - 0.019 14.4 0.3 0.034 13.6 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Actin PF00022.19 KND94469.1 - 6e-79 265.5 0.0 3.5e-76 256.4 0.0 2.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KND94469.1 - 0.039 12.8 0.1 1.8 7.3 0.1 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Agglutinin PF07468.11 KND94469.1 - 0.21 11.8 0.0 0.33 11.2 0.0 1.2 1 0 0 1 1 1 0 Agglutinin domain DUF5572 PF17733.1 KND94470.1 - 1.5e-17 63.1 0.6 4e-17 61.8 0.6 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF4880 PF16220.5 KND94470.1 - 0.061 13.2 3.3 0.14 12.1 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) PP2C PF00481.21 KND94471.1 - 2.5e-40 138.8 0.0 4.6e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KND94471.1 - 0.0055 16.6 0.1 0.075 13.0 0.0 2.4 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KND94471.1 - 0.008 15.8 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SLAC1 PF03595.17 KND94472.1 - 0.00016 21.1 14.9 0.0018 17.6 11.2 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel Rhomboid PF01694.22 KND94473.1 - 0.13 12.2 5.4 0.35 10.9 5.4 1.7 1 1 0 1 1 1 0 Rhomboid family Gly-zipper_Omp PF13488.6 KND94473.1 - 0.51 10.4 3.9 0.88 9.6 3.9 1.4 1 0 0 1 1 1 0 Glycine zipper Uds1 PF15456.6 KND94474.1 - 3.8e-39 133.8 0.3 3.8e-39 133.8 0.3 6.0 2 1 2 4 4 4 2 Up-regulated During Septation Atg14 PF10186.9 KND94474.1 - 0.00012 21.3 13.9 0.00012 21.3 13.9 4.2 2 1 2 4 4 4 1 Vacuolar sorting 38 and autophagy-related subunit 14 HR1 PF02185.16 KND94474.1 - 0.0016 18.5 32.9 0.9 9.7 1.0 7.7 6 2 0 6 6 6 4 Hr1 repeat HMG_box PF00505.19 KND94474.1 - 0.064 13.7 0.1 0.31 11.5 0.1 2.2 1 0 0 1 1 1 0 HMG (high mobility group) box DUF4407 PF14362.6 KND94474.1 - 0.27 10.5 60.5 0.089 12.1 5.1 4.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 KND94474.1 - 0.28 11.6 0.0 0.28 11.6 0.0 8.7 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 KND94474.1 - 0.37 8.9 0.0 0.37 8.9 0.0 5.0 3 1 0 3 3 3 0 HOOK protein Tcp11 PF05794.13 KND94475.1 - 1.2e-110 370.7 0.3 1.8e-110 370.1 0.3 1.2 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_M75 PF09375.10 KND94475.1 - 0.048 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Imelysin DUF1242 PF06842.12 KND94477.1 - 6.5e-18 64.2 0.2 9.6e-18 63.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 KND94478.1 - 1.8e-18 66.3 0.1 2.8e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 KND94478.1 - 0.0032 17.4 0.0 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 KND94478.1 - 0.0051 17.2 0.7 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DGF-1_C PF11040.8 KND94478.1 - 0.047 13.7 1.4 0.079 13.0 1.4 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CENP-T_C PF15511.6 KND94478.1 - 0.048 13.8 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KND94478.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit EamA PF00892.20 KND94479.1 - 3.2e-20 72.7 24.8 2.4e-10 40.7 5.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family NMN_transporter PF04973.12 KND94479.1 - 0.46 10.4 7.0 9.6 6.1 0.5 3.3 1 1 2 3 3 3 0 Nicotinamide mononucleotide transporter RasGEF PF00617.19 KND94480.1 - 5.4e-47 160.3 0.5 1e-46 159.4 0.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KND94480.1 - 6.2e-10 39.3 0.4 1.6e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif FtsK_SpoIIIE PF01580.18 KND94480.1 - 0.048 13.0 0.2 22 4.3 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KND94480.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-HIT PF04438.16 KND94482.1 - 6.5e-10 38.7 11.7 1.2e-09 37.9 11.7 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KND94482.1 - 0.00012 22.1 6.6 0.00012 22.1 6.6 1.7 2 0 0 2 2 2 1 MYND finger Nfu_N PF08712.11 KND94483.1 - 8.9e-29 99.4 0.0 2.4e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KND94483.1 - 1.1e-27 95.9 0.0 2e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.12 KND94484.1 - 2.5e-28 98.2 1.2 2.5e-28 98.2 1.2 1.8 2 0 0 2 2 2 1 PSP1 C-terminal conserved region SUIM_assoc PF16619.5 KND94484.1 - 0.0035 17.4 20.7 0.014 15.5 9.5 3.8 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 DUF853 PF05872.12 KND94484.1 - 0.14 10.7 1.1 0.22 10.1 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4834 PF16118.5 KND94484.1 - 1.5 9.8 6.8 15 6.6 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 KND94484.1 - 4.7 6.2 6.1 9.4 5.2 6.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Uricase PF01014.18 KND94486.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Uricase CDC14 PF08045.11 KND94486.1 - 0.43 9.6 4.3 0.71 8.9 4.3 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Ribosomal_L15e PF00827.17 KND94487.1 - 2.5e-90 301.4 11.3 3e-90 301.1 11.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.19 KND94488.1 - 6.1e-57 186.2 10.6 4e-07 29.4 0.1 8.6 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat PUF PF00806.19 KND94489.1 - 4e-57 186.8 10.6 3.8e-07 29.4 0.1 8.6 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Rad51 PF08423.11 KND94490.1 - 1.8e-43 148.7 0.0 3.9e-43 147.6 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KND94490.1 - 3.3e-07 30.1 0.0 6.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KND94490.1 - 1.5e-05 24.6 0.2 0.00014 21.4 0.2 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KND94490.1 - 0.0086 15.4 0.1 0.043 13.2 0.1 1.9 1 1 0 1 1 1 1 KaiC Speriolin_N PF15058.6 KND94490.1 - 0.015 15.4 2.1 0.027 14.5 2.1 1.4 1 0 0 1 1 1 0 Speriolin N terminus AAA_24 PF13479.6 KND94490.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KND94491.1 - 2.3e-31 108.9 0.0 2.4e-15 56.7 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94491.1 - 2e-18 66.8 0.0 5.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND94491.1 - 1.7e-07 31.4 0.0 7.3e-07 29.3 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4692 PF15763.5 KND94491.1 - 0.022 15.2 2.2 0.022 15.2 2.2 2.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) UvrD-helicase PF00580.21 KND94491.1 - 0.35 10.3 0.1 0.35 10.3 0.1 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Tetraspanin PF00335.20 KND94492.1 - 4.6e-05 23.2 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF4203 PF13886.6 KND94492.1 - 0.0022 17.7 3.8 0.0022 17.7 3.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) YGGT PF02325.17 KND94492.1 - 0.021 15.3 0.7 0.062 13.7 0.0 2.1 2 1 0 2 2 2 0 YGGT family AzlD PF05437.12 KND94492.1 - 0.066 13.4 0.5 0.066 13.4 0.5 2.8 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Glyco_hydro_72 PF03198.14 KND94493.1 - 3.2e-92 309.2 0.1 4.9e-92 308.5 0.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KND94493.1 - 0.022 14.2 0.1 0.069 12.6 0.1 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Ras PF00071.22 KND94494.1 - 7.3e-51 172.0 0.0 1.6e-39 135.2 0.1 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KND94494.1 - 2.2e-29 102.1 0.0 1.1e-18 67.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND94494.1 - 1.4e-11 44.2 0.0 4.7e-11 42.4 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KND94494.1 - 1.2e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KND94494.1 - 1.2e-06 28.2 0.1 1.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KND94494.1 - 7.4e-05 22.8 0.0 0.00023 21.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND94494.1 - 0.00018 21.5 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 KND94494.1 - 0.018 14.8 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KND94494.1 - 0.021 15.1 0.1 0.85 9.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 KND94494.1 - 0.13 12.8 1.0 0.58 10.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter PMT PF02366.18 KND94495.1 - 6.1e-85 284.7 13.9 6.1e-85 284.7 13.9 2.5 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KND94495.1 - 3.5e-65 219.3 14.1 3.5e-65 219.3 14.1 1.8 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KND94495.1 - 1.9e-36 125.7 0.4 2.9e-36 125.1 0.4 1.1 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KND94495.1 - 3.2 7.6 12.3 0.036 13.9 1.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) WW PF00397.26 KND94496.1 - 2.8e-09 36.9 5.6 5.2e-09 36.0 5.6 1.5 1 0 0 1 1 1 1 WW domain Choline_transpo PF04515.12 KND94497.1 - 1.6e-31 109.8 23.2 1.6e-31 109.8 23.2 2.8 1 1 0 2 2 2 1 Plasma-membrane choline transporter Cys_Met_Meta_PP PF01053.20 KND94498.1 - 3.9e-150 499.6 0.0 4.4e-150 499.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KND94498.1 - 9e-10 38.4 0.1 1.6e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KND94498.1 - 2.3e-08 33.6 0.0 4.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KND94498.1 - 1.1e-07 31.1 0.4 1.9e-07 30.4 0.4 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND94498.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KND94498.1 - 0.0013 17.4 0.1 0.0016 17.0 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 KND94498.1 - 0.042 12.5 0.0 0.063 12.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 KND94498.1 - 0.056 13.7 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain AMP-binding PF00501.28 KND94500.1 - 1.2e-85 287.7 0.0 1.4e-85 287.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.23 KND94501.1 - 2.5e-17 63.3 12.5 2.9e-17 63.0 12.5 1.0 1 0 0 1 1 1 1 Membrane-associating domain RHD3 PF05879.12 KND94502.1 - 0 1037.2 0.0 0 1037.0 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KND94502.1 - 7e-09 35.3 0.1 1.1e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KND94502.1 - 7.8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KND94502.1 - 4.4e-05 23.5 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KND94502.1 - 0.00057 20.2 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cys_Met_Meta_PP PF01053.20 KND94502.1 - 0.01 14.4 0.2 0.016 13.8 0.2 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Septin PF00735.18 KND94502.1 - 0.05 12.9 0.1 0.084 12.1 0.1 1.3 1 0 0 1 1 1 0 Septin HLH PF00010.26 KND94504.1 - 1.3e-08 34.6 0.0 5.9e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CAP_N PF01213.19 KND94504.1 - 0.029 13.9 3.5 0.056 12.9 2.5 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CDC45 PF02724.14 KND94504.1 - 0.72 8.1 13.4 1.1 7.4 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PRIMA1 PF16101.5 KND94504.1 - 2.5 8.2 4.5 0.79 9.8 1.3 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 VIR_N PF15912.5 KND94504.1 - 3.6 7.1 21.0 0.51 9.9 1.1 2.3 2 0 0 2 2 2 0 Virilizer, N-terminal GET2 PF08690.10 KND94505.1 - 1.9e-47 162.5 0.0 2.2e-47 162.2 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Sec16_C PF12931.7 KND94507.1 - 1.9e-10 40.9 0.2 1.3e-09 38.2 0.2 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KND94507.1 - 2.2e-10 40.5 0.0 2.2e-10 40.5 0.0 3.9 4 1 1 5 5 5 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KND94507.1 - 2.8e-06 28.0 3.3 0.023 15.6 0.2 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_N PF14781.6 KND94507.1 - 0.12 12.3 0.0 2.4 8.1 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Phytochelatin_C PF09328.10 KND94507.1 - 0.2 11.0 0.1 0.34 10.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) RRM_1 PF00076.22 KND94508.1 - 6.1e-17 61.2 0.0 8.2e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND94508.1 - 9.6e-05 22.4 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KND94508.1 - 0.004 17.1 0.0 0.0078 16.2 0.0 1.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KND94508.1 - 0.056 13.4 0.0 0.093 12.7 0.0 1.5 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KND94508.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif B12D PF06522.11 KND94509.1 - 0.00067 19.4 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 KND94510.1 - 1.3e-17 63.8 4.6 1.5e-17 63.6 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 KND94510.1 - 0.029 14.4 1.4 0.048 13.7 1.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 KND94510.1 - 0.045 13.7 1.6 0.047 13.6 0.9 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 KND94510.1 - 0.23 11.0 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 KND94511.1 - 9.2e-70 233.7 0.3 1.7e-69 232.8 0.3 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain LacI PF00356.21 KND94511.1 - 0.078 12.8 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2407 PF10302.9 KND94511.1 - 0.57 10.8 5.4 9.9 6.8 0.1 2.8 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain S10_plectin PF03501.15 KND94512.1 - 6.5e-42 141.5 0.1 7.8e-42 141.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 KND94513.1 - 2.1e-25 88.7 1.0 5.5e-25 87.4 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KND94513.1 - 3.3e-16 59.4 0.0 5.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KND94513.1 - 1.7e-12 47.3 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KND94513.1 - 4.4e-08 34.2 0.0 9.5e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KND94513.1 - 0.00084 19.6 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KND94513.1 - 0.0019 17.5 0.1 0.003 16.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Staph_opine_DH PF10100.9 KND94513.1 - 0.039 12.6 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase NAD_binding_8 PF13450.6 KND94513.1 - 0.079 13.2 0.1 0.18 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KND94513.1 - 0.096 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HA2 PF04408.23 KND94514.1 - 3.4e-17 62.7 0.1 8.3e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KND94514.1 - 8.8e-16 58.1 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KND94514.1 - 4.2e-13 49.6 0.0 1.1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KND94514.1 - 0.00079 19.7 0.2 0.0041 17.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 KND94514.1 - 0.0032 17.3 1.5 0.038 13.8 1.5 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KND94514.1 - 0.0043 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND94514.1 - 0.0092 16.3 0.0 0.031 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KND94514.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein HIRAN PF08797.11 KND94514.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain AAA_14 PF13173.6 KND94514.1 - 0.17 11.9 0.3 15 5.6 0.0 2.6 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 KND94514.1 - 0.22 11.1 0.2 4 7.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KND94514.1 - 0.68 10.4 2.5 1.8 9.0 2.5 1.7 1 1 0 1 1 1 0 AAA domain SKG6 PF08693.10 KND94515.1 - 0.051 13.0 2.7 0.089 12.2 2.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 KND94515.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KND94515.1 - 0.16 12.8 0.0 0.65 10.9 0.0 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3827 PF12877.7 KND94515.1 - 0.19 10.1 0.2 0.33 9.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Shugoshin_N PF07558.11 KND94516.1 - 1.4e-15 56.9 5.9 3.1e-15 55.8 5.9 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KND94516.1 - 1.3e-10 40.8 4.7 1.3e-10 40.8 4.7 2.7 3 0 0 3 3 3 1 Shugoshin C terminus Fez1 PF06818.15 KND94516.1 - 3 8.3 7.2 4.5 7.7 0.5 2.5 2 0 0 2 2 2 0 Fez1 Metallophos_2 PF12850.7 KND94517.1 - 7.9e-11 42.4 0.0 1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NUC173 PF08161.12 KND94518.1 - 1.1e-76 257.1 1.5 1.8e-74 249.8 0.2 3.2 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 KND94518.1 - 0.027 14.8 0.4 23 5.5 0.0 4.1 3 1 0 3 3 3 0 HEAT repeats HEAT PF02985.22 KND94518.1 - 0.19 12.0 0.3 68 4.1 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DUF2293 PF10056.9 KND94519.1 - 4.3e-33 113.4 0.2 1.3e-32 111.9 0.2 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Hydrolase_6 PF13344.6 KND94519.1 - 0.044 13.9 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SKG6 PF08693.10 KND94520.1 - 4.5e-07 29.2 3.8 1.2e-06 27.8 3.8 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 KND94520.1 - 0.0032 17.4 0.1 0.0032 17.4 0.1 3.3 1 1 1 2 2 2 1 TMEM154 protein family CcmD PF04995.14 KND94520.1 - 0.022 14.8 1.4 0.035 14.2 1.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KND94520.1 - 0.049 13.9 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CD34_antigen PF06365.12 KND94520.1 - 0.079 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF2681 PF10883.8 KND94520.1 - 0.15 12.5 0.1 0.26 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF5305 PF17231.2 KND94520.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ndc1_Nup PF09531.10 KND94520.1 - 8.5 4.9 17.5 14 4.2 17.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COesterase PF00135.28 KND94521.1 - 3e-61 207.8 0.0 3.8e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KND94521.1 - 1.8e-08 34.5 2.9 1.9e-06 27.9 1.6 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold DASH_Dad2 PF08654.10 KND94523.1 - 1.3e-32 112.1 0.4 1.3e-32 112.1 0.4 1.5 2 0 0 2 2 2 1 DASH complex subunit Dad2 HAUS2 PF15003.6 KND94523.1 - 0.044 13.5 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 RasGEF PF00617.19 KND94524.1 - 3.3e-51 174.0 0.0 6.1e-51 173.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KND94524.1 - 1.7e-15 57.2 0.0 5.5e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KND94524.1 - 2.1e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KND94524.1 - 6.1e-05 22.5 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain ATP-grasp_2 PF08442.10 KND94526.1 - 3.3e-77 258.6 0.6 3.3e-77 258.6 0.6 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KND94526.1 - 1.8e-27 96.0 0.6 3.7e-27 95.0 0.6 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KND94526.1 - 3.9e-07 29.8 0.2 8.4e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KND94526.1 - 0.00032 20.5 1.6 0.0073 16.1 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 KND94526.1 - 0.026 14.8 0.1 0.62 10.4 0.0 2.8 2 1 1 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain PSD1 PF07587.11 KND94526.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Tai4 PF16695.5 KND94526.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein p450 PF00067.22 KND94527.1 - 2e-20 73.0 0.0 1.3e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Snf7 PF03357.21 KND94528.1 - 2.1e-34 118.6 9.1 2.8e-34 118.2 9.1 1.1 1 0 0 1 1 1 1 Snf7 DUF2203 PF09969.9 KND94528.1 - 0.55 11.0 0.1 0.55 11.0 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.8 KND94528.1 - 2.5 8.5 12.3 1.1 9.6 4.5 2.3 2 0 0 2 2 2 0 YlqD protein Fructosamin_kin PF03881.14 KND94529.1 - 4.3e-65 219.8 0.0 8.4e-65 218.8 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KND94529.1 - 4.1e-05 23.6 0.0 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1741 PF08427.10 KND94530.1 - 2.9e-88 295.5 0.2 4.8e-88 294.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DNA_binding_1 PF01035.20 KND94532.1 - 5.3e-28 97.0 0.0 8.3e-28 96.3 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fe-S_biosyn PF01521.20 KND94533.1 - 7.1e-19 68.0 0.0 9.3e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.7 KND94533.1 - 0.11 12.7 0.2 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF726 PF05277.12 KND94534.1 - 2.4e-99 332.5 0.0 3.1e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) IMS PF00817.20 KND94535.1 - 4.4e-38 130.6 0.0 6.6e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KND94535.1 - 9.5e-13 48.9 0.0 1.7e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KND94535.1 - 0.066 12.8 0.3 0.14 11.8 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DUF974 PF06159.13 KND94536.1 - 3.1e-83 279.4 0.0 3.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 KND94537.1 - 4.3e-49 167.0 0.1 8.2e-49 166.1 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KND94537.1 - 3.3e-14 53.4 0.0 1e-13 51.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KND94537.1 - 3.9e-14 52.4 0.9 7.9e-14 51.4 0.9 1.6 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.22 KND94537.1 - 6.3e-05 22.8 4.4 0.00012 21.9 4.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KND94537.1 - 0.0035 17.6 6.3 0.0068 16.7 6.3 1.5 1 0 0 1 1 1 1 C1 domain PHD PF00628.29 KND94537.1 - 0.02 14.8 5.3 0.046 13.6 5.3 1.7 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KND94537.1 - 0.062 13.4 1.9 0.13 12.4 1.9 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 KND94537.1 - 0.24 11.4 4.2 0.45 10.5 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 KND94537.1 - 2.6 8.5 4.7 5.3 7.5 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain DENN PF02141.21 KND94538.1 - 3.3e-53 180.4 0.1 4.6e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KND94538.1 - 2.5e-14 53.8 0.0 4.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 KND94538.1 - 0.02 14.9 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis ALS_ss_C PF10369.9 KND94539.1 - 1.7e-13 50.6 0.0 1.4e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KND94539.1 - 2e-13 49.8 0.1 3.8e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KND94539.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KND94539.1 - 0.096 12.7 0.1 11 6.1 0.0 2.7 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.29 KND94540.1 - 3.9e-05 23.4 0.1 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 KH domain DUF3712 PF12505.8 KND94541.1 - 4.4e-08 33.4 0.4 3.1e-06 27.5 0.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF2417 PF10329.9 KND94541.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Region of unknown function (DUF2417) OTCace_N PF02729.21 KND94542.1 - 3e-44 150.6 0.3 4.3e-44 150.1 0.3 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KND94542.1 - 1e-43 149.1 0.0 1.6e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_hydro_15 PF00723.21 KND94543.1 - 1.1e-95 321.1 0.0 1.5e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KND94543.1 - 6.8e-32 109.2 0.5 1.5e-31 108.2 0.5 1.6 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 KND94544.1 - 9.3e-178 592.7 63.2 1.1e-177 592.5 63.2 1.0 1 0 0 1 1 1 1 SART-1 family Pyridoxal_deC PF00282.19 KND94545.1 - 1.2e-72 244.7 0.0 1.6e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_3 PF00202.21 KND94546.1 - 8.6e-108 360.6 0.0 1.1e-107 360.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KND94546.1 - 6.2e-05 22.3 0.0 0.00012 21.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II NHase_beta PF02211.15 KND94546.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Mcl1_mid PF12341.8 KND94547.1 - 4.5e-101 338.1 0.3 2e-99 332.7 0.0 2.5 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KND94547.1 - 7.5e-20 70.9 0.7 1.9e-07 31.6 0.0 7.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94547.1 - 1e-15 57.8 0.0 5.9e-05 23.3 0.1 6.6 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KND94547.1 - 1.7e-06 27.4 0.0 7.2e-06 25.3 0.0 1.8 1 1 1 2 2 2 1 Coatomer WD associated region Ge1_WD40 PF16529.5 KND94547.1 - 0.0024 16.9 0.2 0.37 9.7 0.0 3.5 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KND94547.1 - 0.014 15.2 0.6 0.044 13.7 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 KND94547.1 - 0.02 14.9 1.6 0.065 13.3 1.6 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.32 KND94548.1 - 8.4e-17 61.3 7.0 0.0026 18.6 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KND94548.1 - 0.0014 17.4 1.6 0.095 11.3 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF627 PF04781.12 KND94548.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Ndc1_Nup PF09531.10 KND94549.1 - 2.7e-167 558.1 12.0 5e-89 299.7 13.4 2.1 1 1 1 2 2 2 2 Nucleoporin protein Ndc1-Nup DUF4129 PF13559.6 KND94550.1 - 2.9e-05 24.2 0.0 9.4e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 KND94550.1 - 0.00024 21.1 0.1 0.028 14.4 0.0 2.3 2 0 0 2 2 2 2 NICE-3 protein HSF_DNA-bind PF00447.17 KND94552.1 - 4.8e-28 97.6 1.2 8e-28 96.9 1.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Sugarporin_N PF11471.8 KND94552.1 - 0.15 12.0 1.0 0.35 10.9 1.0 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pyr_redox_2 PF07992.14 KND94553.1 - 1.1e-36 126.6 0.1 1.3e-36 126.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND94553.1 - 2.9e-12 47.0 0.1 3.4e-09 37.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND94553.1 - 2.7e-07 30.5 5.1 0.051 13.2 0.6 4.1 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KND94553.1 - 3.7e-07 30.3 2.0 0.44 10.5 0.0 4.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KND94553.1 - 1.1e-06 28.0 0.4 0.0031 16.6 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KND94553.1 - 1.7e-05 24.3 0.1 9.2e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND94553.1 - 8.2e-05 21.9 0.4 0.00091 18.5 0.1 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KND94553.1 - 0.00056 20.1 0.3 0.55 10.5 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 KND94553.1 - 0.0013 19.0 0.0 0.19 12.0 0.1 2.7 2 0 0 2 2 2 1 TrkA-N domain PALP PF00291.25 KND94553.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arylsulfotran_N PF17425.2 KND94553.1 - 0.0034 17.4 0.0 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Arylsulfotransferase Ig-like domain ThiF PF00899.21 KND94553.1 - 0.021 14.2 0.7 0.067 12.5 0.1 1.9 2 0 0 2 2 2 0 ThiF family ApbA PF02558.16 KND94553.1 - 0.022 14.4 0.1 0.81 9.3 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KND94553.1 - 0.042 14.1 0.1 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 KND94553.1 - 0.071 12.0 1.2 9.6 4.9 0.3 3.0 3 0 0 3 3 3 0 Tryptophan halogenase SIS PF01380.22 KND94553.1 - 0.18 11.6 0.4 17 5.3 0.0 2.5 2 0 0 2 2 2 0 SIS domain Zn_clus PF00172.18 KND94554.1 - 5.5e-10 39.2 10.7 1.2e-09 38.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND94554.1 - 2.2e-06 26.9 0.0 4.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 60KD_IMP PF02096.20 KND94555.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Syntaxin_2 PF14523.6 KND94556.1 - 7.3e-24 84.1 5.4 7.3e-24 84.1 5.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KND94556.1 - 6.9e-13 48.4 2.7 6.9e-13 48.4 2.7 2.4 3 0 0 3 3 3 1 SNARE domain DUF883 PF05957.13 KND94556.1 - 0.0073 16.9 11.3 0.02 15.5 0.1 3.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF883) Elf4 PF07011.11 KND94556.1 - 0.069 13.1 4.3 2.7 7.9 0.2 2.9 2 1 0 2 2 2 0 Early Flowering 4 domain Prominin PF05478.11 KND94556.1 - 0.49 8.3 8.8 0.67 7.8 6.2 1.9 1 1 1 2 2 2 0 Prominin T2SSF PF00482.23 KND94556.1 - 0.99 9.4 3.9 1.3 9.0 0.3 2.6 2 2 1 3 3 3 0 Type II secretion system (T2SS), protein F Syntaxin PF00804.25 KND94556.1 - 1.5 8.4 18.9 1.1 8.9 14.1 2.8 2 1 0 2 2 2 0 Syntaxin T3SSipB PF16535.5 KND94556.1 - 2 8.8 16.4 0.059 13.9 7.4 2.4 3 0 0 3 3 3 0 Type III cell invasion protein SipB Occludin_ELL PF07303.13 KND94556.1 - 2.8 8.7 6.9 1 10.1 1.7 2.5 2 1 0 2 2 2 0 Occludin homology domain AMP-binding PF00501.28 KND94557.1 - 9.5e-85 284.7 0.1 1.2e-84 284.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND94557.1 - 4.3e-26 91.7 2.3 3.5e-25 88.8 1.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KND94557.1 - 5.8e-20 71.0 0.3 1.5e-19 69.6 0.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 KND94557.1 - 0.14 12.1 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) DNA_pol3_delta2 PF13177.6 KND94559.1 - 2.5e-11 43.6 0.1 5.9e-11 42.4 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KND94559.1 - 5.5e-07 30.1 0.1 1.2e-06 28.9 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND94559.1 - 2.2e-06 28.0 0.1 5.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KND94559.1 - 7.2e-05 23.2 0.7 0.00088 19.7 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KND94559.1 - 0.0007 19.4 0.3 0.002 17.9 0.3 1.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 KND94559.1 - 0.0012 19.2 0.0 0.0058 17.0 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain Sigma54_activ_2 PF14532.6 KND94559.1 - 0.011 15.9 0.3 0.59 10.2 0.3 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KND94559.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 KND94559.1 - 0.025 15.1 0.2 0.049 14.1 0.2 1.8 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KND94559.1 - 0.053 12.3 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ATPase_2 PF01637.18 KND94559.1 - 0.083 12.8 0.1 0.29 11.0 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta PF06144.13 KND94559.1 - 0.085 12.6 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF4025 PF13217.6 KND94559.1 - 0.091 12.6 0.5 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4025) Prenyltransf PF01255.19 KND94559.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase RPN6_N PF18055.1 KND94560.1 - 2.5e-42 143.9 1.8 2.5e-42 143.9 1.8 2.4 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KND94560.1 - 1.2e-20 74.0 0.1 5.9e-20 71.7 0.1 2.2 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 KND94560.1 - 4.4e-10 39.1 1.2 1.1e-09 37.8 1.2 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KND94560.1 - 6.4e-05 22.6 0.1 6.4e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 DDRGK domain TPR_MalT PF17874.1 KND94560.1 - 0.00026 20.5 0.6 0.00026 20.5 0.6 2.3 3 0 0 3 3 3 1 MalT-like TPR region TPR_12 PF13424.6 KND94560.1 - 0.0011 19.2 16.4 0.026 14.8 1.7 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KND94560.1 - 0.019 14.8 0.0 32 4.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 KND94560.1 - 0.022 14.7 2.4 1.3 9.2 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DprA_WH PF17782.1 KND94560.1 - 0.04 14.0 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 DprA winged helix domain SesA PF17107.5 KND94560.1 - 0.16 12.2 2.6 18 5.5 0.1 3.5 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_2 PF07719.17 KND94560.1 - 0.16 12.1 6.8 13 6.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KND94560.1 - 0.43 11.5 6.6 18 6.4 0.1 5.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KND94560.1 - 4 8.3 8.2 14 6.5 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 KND94562.1 - 3.6e-48 161.4 4.8 1.1e-16 60.6 0.0 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein UcrQ PF02939.16 KND94562.1 - 0.018 15.0 0.1 0.07 13.1 0.1 2.0 1 0 0 1 1 1 0 UcrQ family Mak10 PF04112.13 KND94563.1 - 3.5e-64 215.3 0.0 6.9e-64 214.4 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase MCR_alpha_N PF02745.15 KND94563.1 - 0.057 12.8 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Ribosomal_L16 PF00252.18 KND94564.1 - 1.7e-30 105.7 1.2 2.4e-30 105.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KND94565.1 - 1e-57 194.7 0.0 2.9e-57 193.2 0.0 1.8 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KND94565.1 - 9.6e-15 54.7 0.0 2.8e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KND94565.1 - 3.3e-08 34.0 0.1 2.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KND94565.1 - 0.00024 21.1 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 KND94565.1 - 0.00083 19.9 0.1 0.013 16.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KND94565.1 - 0.0021 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KND94565.1 - 0.0021 18.3 0.0 0.025 14.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KND94565.1 - 0.011 16.2 2.8 0.016 15.6 0.1 2.6 2 1 0 2 2 1 0 AAA ATPase domain AAA_30 PF13604.6 KND94565.1 - 0.016 14.9 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KND94565.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KND94565.1 - 0.036 14.0 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 KND94565.1 - 0.037 14.0 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND94565.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KND94565.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KND94565.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 KND94565.1 - 0.45 10.7 0.0 0.45 10.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain GrpE PF01025.19 KND94567.1 - 3.4e-48 163.4 3.7 4.4e-48 163.1 3.7 1.1 1 0 0 1 1 1 1 GrpE ApoLp-III PF07464.11 KND94567.1 - 0.052 13.6 0.5 0.1 12.7 0.5 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) GCIP PF13324.6 KND94567.1 - 0.08 12.5 2.9 0.11 12.0 2.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glyco_hydro_67C PF07477.12 KND94567.1 - 0.14 11.7 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus CN_hydrolase PF00795.22 KND94568.1 - 3.6e-30 105.2 0.0 5e-29 101.4 0.0 2.1 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Pro_racemase PF05544.11 KND94569.1 - 1.3e-124 415.5 0.0 1.5e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Phage_cap_E PF03864.15 KND94569.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein E Peptidase_S28 PF05577.12 KND94570.1 - 3.3e-42 144.8 0.1 5.2e-42 144.2 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mito_carr PF00153.27 KND94571.1 - 1.4e-66 220.5 0.7 4.2e-22 77.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MINDY_DUB PF04424.13 KND94572.1 - 8.4e-27 93.5 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase Steroid_dh PF02544.16 KND94572.1 - 5.1e-20 72.0 0.1 7e-14 52.1 0.2 2.3 2 0 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KND94572.1 - 0.00018 21.1 0.4 0.00032 20.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1977 PF09320.11 KND94573.1 - 6.1e-29 100.4 0.0 1.5e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KND94573.1 - 5.9e-19 68.0 0.1 1e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S19 PF00203.21 KND94574.1 - 1e-27 95.8 0.0 1.2e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 KND94575.1 - 5.2e-26 90.4 0.4 7.7e-26 89.8 0.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TAF4 PF05236.14 KND94575.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family VIR_N PF15912.5 KND94575.1 - 0.32 10.6 2.8 0.4 10.2 2.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal FoP_duplication PF13865.6 KND94575.1 - 1.4 9.6 6.8 3.4 8.3 6.6 1.8 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF4603 PF15376.6 KND94576.1 - 1.9 5.8 7.9 2.4 5.4 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) WLM PF08325.10 KND94577.1 - 8.7e-50 169.5 0.3 1.4e-49 168.8 0.1 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KND94577.1 - 0.0017 18.5 0.5 0.004 17.2 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 ubiquitin PF00240.23 KND94577.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Sde2_N_Ubi PF13019.6 KND94577.1 - 0.17 11.7 4.7 2.5 7.9 0.0 3.2 2 1 1 3 3 3 0 Silencing defective 2 N-terminal ubiquitin domain SprT-like PF10263.9 KND94577.1 - 1.7 8.5 6.4 3.6 7.5 6.3 1.6 1 1 0 1 1 1 0 SprT-like family OB_NTP_bind PF07717.16 KND94579.1 - 1.8e-24 85.9 0.0 1.5e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KND94579.1 - 8.1e-19 67.9 0.0 2.1e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KND94579.1 - 1.7e-11 44.4 0.0 1.3e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND94579.1 - 3.7e-09 36.6 0.1 7.9e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND94579.1 - 1e-06 29.1 0.0 2.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KND94579.1 - 7.5e-05 22.4 0.3 0.00033 20.4 0.3 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 KND94579.1 - 0.00051 19.8 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND94579.1 - 0.0018 18.6 0.1 0.0035 17.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KND94579.1 - 0.0088 16.5 1.1 0.086 13.3 0.1 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KND94579.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 KND94579.1 - 0.015 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 KND94579.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 KND94579.1 - 0.031 14.3 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 KND94579.1 - 0.066 12.9 0.0 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 KND94579.1 - 0.13 12.8 0.0 0.34 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 KND94580.1 - 3.5e-23 82.2 0.0 4.2e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V B12-binding PF02310.19 KND94580.1 - 0.018 15.1 0.1 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain RusA PF05866.11 KND94580.1 - 0.18 12.4 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA Ribonuc_L-PSP PF01042.21 KND94581.1 - 1.8e-14 53.8 0.0 2.1e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aim19 PF10315.9 KND94582.1 - 0.0014 18.9 1.5 0.011 16.0 0.3 2.1 1 1 1 2 2 2 1 Altered inheritance of mitochondria protein 19 Zn_clus PF00172.18 KND94583.1 - 2.5e-07 30.7 13.0 4e-07 30.1 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 KND94583.1 - 4.9 5.6 6.0 5.2 5.5 6.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF2975 PF11188.8 KND94585.1 - 0.2 11.6 1.5 3.5 7.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) adh_short PF00106.25 KND94587.1 - 1.9e-21 76.5 0.0 2.7e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND94587.1 - 2.2e-17 63.4 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KND94587.1 - 9.7e-05 22.3 0.1 0.00088 19.2 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KND94587.1 - 0.00011 22.1 0.0 0.00026 21.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND94587.1 - 0.00077 19.0 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KND94587.1 - 0.01 15.3 0.0 0.061 12.7 0.0 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KND94587.1 - 0.018 14.2 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Fringe PF02434.16 KND94588.1 - 5e-08 32.7 0.0 8.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 KND94588.1 - 5.4e-06 26.0 0.0 8.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF604 tRNA-synt_1 PF00133.22 KND94591.1 - 5.2e-220 731.8 0.0 6.9e-220 731.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND94591.1 - 1.4e-23 83.5 0.0 3.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KND94591.1 - 1.7e-14 53.4 0.0 1.4e-06 27.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KND94591.1 - 0.01 15.2 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain SWIB PF02201.18 KND94593.1 - 1e-20 73.3 0.0 2.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Mo25 PF08569.11 KND94594.1 - 2e-124 415.3 0.1 2.2e-124 415.1 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Sec7_N PF12783.7 KND94594.1 - 0.032 14.1 0.6 1 9.2 0.0 2.9 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ANAPC_CDC26 PF10471.9 KND94595.1 - 0.021 15.7 0.8 0.081 13.8 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 CENP-B_dimeris PF09026.10 KND94595.1 - 0.31 11.5 9.7 0.64 10.4 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KND94595.1 - 0.48 8.5 4.1 0.6 8.1 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KND94595.1 - 1.7 6.7 3.6 2.1 6.5 3.6 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 KND94596.1 - 1e-67 228.3 0.0 1.4e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94596.1 - 7.2e-35 120.5 0.0 1.1e-24 87.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KND94596.1 - 0.00014 21.3 0.3 0.046 13.0 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Haspin_kinase PF12330.8 KND94596.1 - 0.00027 20.0 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KND94596.1 - 0.0049 16.3 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND94596.1 - 0.0054 16.7 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KND94596.1 - 0.015 14.9 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SNARE PF05739.19 KND94597.1 - 7.5e-07 29.0 1.2 1.6e-06 28.0 1.2 1.6 1 0 0 1 1 1 1 SNARE domain DUF812 PF05667.11 KND94597.1 - 0.0027 16.7 0.1 0.0032 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Not3 PF04065.15 KND94597.1 - 0.0031 17.0 0.7 1.2 8.6 0.0 2.1 2 0 0 2 2 2 2 Not1 N-terminal domain, CCR4-Not complex component DUF16 PF01519.16 KND94597.1 - 0.007 16.8 1.3 0.16 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 DUF4407 PF14362.6 KND94597.1 - 0.025 13.9 7.7 0.1 11.9 7.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 KND94597.1 - 0.22 11.8 5.0 6.2 7.1 0.7 3.3 2 2 1 3 3 3 0 Proteins of 100 residues with WXG PilJ PF13675.6 KND94597.1 - 0.5 10.4 9.4 0.09 12.8 3.4 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term ADIP PF11559.8 KND94597.1 - 2.9 7.9 9.8 2 8.5 2.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Sfi1 PF08457.10 KND94599.1 - 2.5e-22 79.1 69.4 2.1e-16 59.6 28.7 2.1 2 0 0 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.8 KND94600.1 - 9e-274 909.8 0.0 1.1e-273 909.5 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Mob1_phocein PF03637.17 KND94601.1 - 2.3e-69 232.7 0.0 3.3e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family HET PF06985.11 KND94602.1 - 8.8e-23 81.3 0.0 2.9e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 KND94602.1 - 7.9e-09 36.0 0.0 1.9e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND94602.1 - 6.9e-07 29.7 0.0 1.8e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KND94602.1 - 0.00058 20.1 0.1 0.0025 18.1 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KND94602.1 - 0.096 13.2 0.0 12 6.5 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_23 PF13489.6 KND94603.1 - 6.6e-12 45.6 0.0 8.2e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND94603.1 - 1.8e-07 31.7 0.0 3.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND94603.1 - 0.0001 23.0 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND94603.1 - 0.00017 21.5 0.0 0.00055 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND94603.1 - 0.00049 20.7 0.0 0.001 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KND94603.1 - 0.0028 17.1 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KND94603.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KND94603.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 KND94603.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Skp1_POZ PF03931.15 KND94604.1 - 9.8e-08 32.1 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.13 KND94605.1 - 7.6e-49 165.7 1.3 1.7e-48 164.6 0.0 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KND94605.1 - 1.7e-05 25.4 0.3 2.9e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.29 KND94606.1 - 9.9e-14 51.9 0.0 1.8e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND94606.1 - 3.3e-05 24.3 0.1 0.00014 22.3 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KND94606.1 - 0.00042 20.6 0.3 0.0073 16.6 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 KND94606.1 - 0.014 15.7 0.1 1.5 9.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KND94606.1 - 0.019 15.0 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND94606.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KND94606.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KND94606.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Myb_DNA-binding PF00249.31 KND94607.1 - 4.2e-11 42.8 0.0 8.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND94607.1 - 0.01 16.1 0.7 0.86 9.9 0.1 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KND94607.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like PA26 PF04636.13 KND94607.1 - 7.7 5.3 8.1 15 4.4 8.1 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Aldo_ket_red PF00248.21 KND94608.1 - 1.5e-14 53.9 0.0 2e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.22 KND94609.1 - 5.8e-47 159.3 0.0 7.5e-47 158.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KND94609.1 - 9.8e-21 74.2 0.0 1.7e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KND94609.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 KND94609.1 - 0.054 13.0 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 KND94609.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.10 KND94610.1 - 4.9e-27 93.9 1.4 6.1e-27 93.6 1.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KND94610.1 - 0.077 13.0 0.3 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 CytochromB561_N PF09786.9 KND94611.1 - 0.00024 20.3 0.2 0.00038 19.6 0.2 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal MFS_1 PF07690.16 KND94612.1 - 6.6e-42 143.7 40.3 6.6e-42 143.7 40.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 KND94613.1 - 1.8e-14 54.1 0.0 9.9e-09 35.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KND94613.1 - 1.3e-11 44.4 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 KND94613.1 - 7.8e-08 31.5 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KND94613.1 - 3.5e-05 23.2 0.0 0.00098 18.4 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KND94613.1 - 0.00021 21.0 0.2 0.00084 19.0 0.2 2.1 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KND94613.1 - 0.0029 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 KND94613.1 - 0.0068 16.2 0.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 KND94613.1 - 0.014 14.9 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2920 PF11144.8 KND94613.1 - 0.033 13.4 0.0 5.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DLH PF01738.18 KND94613.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family p450 PF00067.22 KND94614.1 - 1.4e-30 106.4 0.0 8.3e-30 103.9 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.19 KND94615.1 - 5.2e-05 23.2 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family p450 PF00067.22 KND94617.1 - 3.3e-42 144.8 0.0 4.3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chorismate_synt PF01264.21 KND94619.1 - 1.1e-137 458.2 0.0 1.2e-137 458.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Fungal_trans PF04082.18 KND94620.1 - 1.6e-23 83.1 0.0 2.6e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94620.1 - 6.5e-09 35.8 9.0 1.2e-08 34.9 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND94620.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain POX PF07526.11 KND94620.1 - 0.17 12.5 0.1 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 Associated with HOX ADK PF00406.22 KND94621.1 - 1.4e-58 197.3 0.0 1.8e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KND94621.1 - 1.1e-22 80.9 0.0 2.3e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KND94621.1 - 1.4e-17 63.4 0.0 5.4e-17 61.5 0.0 2.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KND94621.1 - 2.9e-05 24.6 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND94621.1 - 0.0017 18.5 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain BLOC1_2 PF10046.9 KND94621.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HOOK PF05622.12 KND94622.1 - 1.1e-11 43.7 50.2 1.1e-11 43.7 50.2 2.4 1 1 1 2 2 2 2 HOOK protein Alliinase_C PF04864.13 KND94622.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Allinase DUF3015 PF11220.8 KND94622.1 - 5.4 6.9 5.7 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3015) Sas6_CC PF18594.1 KND94622.1 - 7 6.5 12.6 9.2 6.2 0.6 4.6 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain DUF2183 PF09949.9 KND94623.1 - 7e-31 106.5 0.0 1.3e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Ribosomal_L28 PF00830.19 KND94625.1 - 3.3e-13 49.6 0.9 6.8e-13 48.6 0.9 1.5 1 0 0 1 1 1 1 Ribosomal L28 family Trp_syntA PF00290.20 KND94626.1 - 1.9e-95 318.6 0.0 3.4e-95 317.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KND94626.1 - 6.4e-48 163.7 1.6 6.4e-48 163.7 1.6 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ATG_C PF09333.11 KND94627.1 - 0.057 13.8 0.6 12 6.3 0.2 3.2 2 1 0 2 2 2 0 Autophagy-related protein C terminal domain Baculo_PEP_C PF04513.12 KND94627.1 - 0.072 13.1 3.1 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg8 PF02991.16 KND94628.1 - 3.2e-50 168.6 0.2 4.6e-50 168.1 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KND94628.1 - 3e-05 24.4 0.0 5.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 KND94629.1 - 2.7e-143 476.1 0.0 3.1e-143 475.9 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase MitMem_reg PF13012.6 KND94630.1 - 1.3e-37 128.7 0.1 3.3e-37 127.3 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KND94630.1 - 1.2e-31 109.2 0.0 2.5e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 KND94630.1 - 0.017 14.8 2.1 0.024 14.3 2.1 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Aminotran_1_2 PF00155.21 KND94631.1 - 9e-25 87.6 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND94631.1 - 4.2e-07 28.9 0.1 6.1e-07 28.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND94631.1 - 7.6e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KND94631.1 - 0.0088 15.4 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase PS-DH PF14765.6 KND94632.1 - 1.6e-68 231.1 0.0 2.5e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 KND94632.1 - 6e-59 199.7 0.3 1.7e-58 198.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KND94632.1 - 3.6e-58 196.4 0.2 7.4e-58 195.4 0.2 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 KND94632.1 - 6.3e-47 160.6 2.1 1e-46 160.0 2.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND94632.1 - 2.3e-31 108.3 0.5 7.3e-31 106.6 0.1 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KND94632.1 - 5.5e-25 88.0 0.0 1.3e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 KND94632.1 - 5.4e-18 65.6 0.0 2.7e-17 63.3 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 KND94632.1 - 2.9e-14 53.2 0.1 1.5e-13 50.9 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KND94632.1 - 5.8e-14 53.3 0.0 9.5e-13 49.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KND94632.1 - 3e-10 40.2 0.0 6.2e-09 35.9 0.0 3.0 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND94632.1 - 3.2e-09 37.4 0.2 5.1e-07 30.3 0.0 4.0 4 0 0 4 4 3 1 Methyltransferase domain adh_short PF00106.25 KND94632.1 - 5.7e-09 35.7 0.3 1.2e-07 31.4 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 KND94632.1 - 2.5e-08 33.8 0.0 7.1e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 KND94632.1 - 1.8e-06 27.7 0.3 1.2e-05 25.0 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_11 PF08241.12 KND94632.1 - 2.5e-05 24.8 0.0 0.00017 22.2 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.12 KND94632.1 - 3e-05 23.9 0.1 7.5e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KND94632.1 - 4.1e-05 23.9 0.1 0.00012 22.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 KND94632.1 - 0.00022 21.0 0.0 0.0008 19.2 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase SAT PF16073.5 KND94632.1 - 0.0077 16.0 0.7 0.016 14.9 0.7 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis GCP_C_terminal PF04130.13 KND94632.1 - 0.049 13.1 0.3 0.12 11.8 0.3 1.6 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal Methyltransf_24 PF13578.6 KND94632.1 - 0.14 13.1 0.3 1.6 9.8 0.0 3.1 4 0 0 4 4 1 0 Methyltransferase domain DREV PF05219.12 KND94632.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase P16-Arc PF04699.14 KND94634.1 - 4.1e-52 176.6 0.0 5e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Methyltransf_11 PF08241.12 KND94635.1 - 2e-09 38.0 0.0 4.2e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND94635.1 - 7.2e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND94635.1 - 2.8e-07 31.2 0.0 5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND94635.1 - 5.2e-07 30.3 0.0 1.6e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND94635.1 - 0.00047 20.0 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND94635.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ala_racemase_N PF01168.20 KND94636.1 - 1.9e-21 76.7 0.0 2.4e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 KND94638.1 - 1.9e-124 416.1 5.5 2.3e-124 415.8 5.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KND94638.1 - 1.2e-44 151.1 0.0 3.6e-44 149.6 0.0 1.9 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KND94638.1 - 5.2e-15 55.7 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 KND94638.1 - 0.0066 16.6 0.1 0.025 14.8 0.1 2.0 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KND94638.1 - 0.016 14.7 0.7 0.058 13.0 0.8 1.9 2 0 0 2 2 2 0 CLASP N terminal AP4E_app_platf PF14807.6 KND94638.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform COG5 PF10392.9 KND94639.1 - 0.0026 17.9 1.0 0.0068 16.6 0.1 2.3 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF812 PF05667.11 KND94639.1 - 0.014 14.3 0.5 0.021 13.7 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4795 PF16043.5 KND94639.1 - 0.083 12.5 1.5 1.1 8.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) COG7 PF10191.9 KND94639.1 - 0.15 10.2 0.0 0.37 9.0 0.0 1.5 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) DUF3486 PF11985.8 KND94639.1 - 1.2 9.5 7.5 0.08 13.4 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3486) Amino_oxidase PF01593.24 KND94640.1 - 1.3e-20 74.1 0.6 1e-12 48.1 0.1 3.1 1 1 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KND94640.1 - 2.4e-13 50.1 0.4 1.7e-12 47.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KND94640.1 - 2.9e-05 23.8 0.7 5.6e-05 22.9 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND94640.1 - 4.2e-05 22.8 0.3 8.5e-05 21.8 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KND94640.1 - 8.6e-05 23.0 0.2 0.00032 21.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KND94640.1 - 0.00075 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 KND94640.1 - 0.002 17.5 0.3 0.0038 16.5 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KND94640.1 - 0.0022 17.3 0.3 0.0068 15.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND94640.1 - 0.0024 17.1 0.1 0.0045 16.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KND94640.1 - 0.0044 15.8 0.4 0.0084 14.9 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KND94640.1 - 0.059 12.7 0.2 0.09 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KND94640.1 - 0.097 11.9 0.0 5.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KND94640.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.13 KND94641.1 - 6.1e-66 222.0 9.0 7.8e-66 221.6 9.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Dynamin_N PF00350.23 KND94642.1 - 1.3e-31 109.9 0.1 2.9e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KND94642.1 - 3.5e-20 72.4 0.0 2.8e-14 53.0 0.0 2.7 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KND94642.1 - 1.4e-06 28.4 0.0 1.2e-05 25.4 0.0 2.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 KND94642.1 - 0.022 15.0 0.0 0.19 11.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KND94642.1 - 0.023 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KND94642.1 - 0.029 14.2 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KND94642.1 - 0.046 14.1 0.3 0.29 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 KND94642.1 - 0.05 13.3 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KND94642.1 - 0.068 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KND94642.1 - 0.074 12.6 0.0 9.9 5.7 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B ATP-synt_F6 PF05511.11 KND94642.1 - 0.11 12.9 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Pkinase_fungal PF17667.1 KND94644.1 - 0.00078 18.3 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KND94644.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KND94644.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PPR_2 PF13041.6 KND94646.1 - 3.1e-15 56.1 1.6 0.00032 20.8 0.1 5.1 2 1 3 5 5 5 4 PPR repeat family PPR PF01535.20 KND94646.1 - 1.1e-10 41.0 8.5 0.00035 20.6 0.0 5.5 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 KND94646.1 - 6.5e-09 35.7 0.7 0.021 14.9 0.0 3.7 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 KND94646.1 - 3.8e-05 23.2 0.7 0.013 14.9 0.1 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP DUF3579 PF12112.8 KND94646.1 - 0.088 13.4 0.6 2.5 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3579) PPR_1 PF12854.7 KND94646.1 - 0.47 10.2 5.2 14 5.5 0.1 4.2 4 0 0 4 4 4 0 PPR repeat MRP-S25 PF13741.6 KND94647.1 - 6.9e-68 228.6 5.3 7.5e-63 212.2 1.6 2.0 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KND94647.1 - 0.013 15.8 0.3 0.036 14.3 0.2 1.9 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 Alg14 PF08660.11 KND94648.1 - 8.4e-40 136.6 0.0 1.5e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ras PF00071.22 KND94648.1 - 0.018 14.6 0.0 2.9 7.5 0.0 2.5 2 1 1 3 3 3 0 Ras family IPK PF03770.16 KND94649.1 - 1.5e-51 175.1 0.0 2.4e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.7 KND94650.1 - 1.2e-20 73.3 35.8 1.2e-05 25.6 3.2 8.6 5 1 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND94650.1 - 9.8e-11 41.3 34.9 0.0001 22.0 3.3 6.7 6 1 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.6 KND94650.1 - 5e-05 23.0 14.1 4.6 7.6 0.1 6.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.6 KND94650.1 - 0.00015 21.3 14.0 0.11 12.0 0.7 4.3 2 2 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 KND94650.1 - 0.24 12.1 18.1 32 5.6 0.2 8.0 8 0 0 8 8 8 0 Leucine Rich Repeat DUF2012 PF09430.10 KND94652.1 - 2.1e-22 79.5 0.0 2.8e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 KND94652.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein DUF202 PF02656.15 KND94653.1 - 3.8e-21 75.3 3.9 3.8e-21 75.3 3.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3382 PF11862.8 KND94653.1 - 0.1 12.9 2.1 0.19 12.0 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) AAA_11 PF13086.6 KND94654.1 - 7.2e-61 206.3 0.6 2.7e-60 204.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KND94654.1 - 4.1e-55 186.5 0.0 6.9e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND94654.1 - 8.3e-13 48.5 0.0 1.5e-11 44.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND94654.1 - 4e-09 37.0 0.0 2e-08 34.7 0.0 2.3 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KND94654.1 - 9.2e-07 28.8 0.0 0.51 10.0 0.0 3.8 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KND94654.1 - 9.9e-06 25.0 0.1 5.4e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KND94654.1 - 1.2e-05 25.0 0.0 3.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KND94654.1 - 2e-05 24.7 0.0 0.00011 22.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND94654.1 - 0.00043 20.1 0.1 0.0053 16.5 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 KND94654.1 - 0.00047 19.3 0.0 0.00088 18.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KND94654.1 - 0.00054 20.2 0.3 0.0054 17.0 0.3 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KND94654.1 - 0.00097 19.0 0.0 0.043 13.7 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 KND94654.1 - 0.0016 18.8 0.1 0.005 17.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KND94654.1 - 0.0017 18.0 0.2 0.11 12.1 0.0 3.4 3 1 1 4 4 3 1 AAA domain Flavi_DEAD PF07652.14 KND94654.1 - 0.0033 17.4 0.0 0.014 15.4 0.1 2.0 2 0 0 2 2 2 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 KND94654.1 - 0.0059 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 KND94654.1 - 0.0073 15.8 0.0 0.04 13.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.6 KND94654.1 - 0.013 14.9 0.0 2.1 7.6 0.0 3.2 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.29 KND94654.1 - 0.014 15.8 0.1 0.089 13.2 0.0 2.4 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KND94654.1 - 0.017 15.6 0.0 0.054 14.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 KND94654.1 - 0.028 14.2 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain 4HB_MCP_1 PF12729.7 KND94654.1 - 0.029 13.9 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction UvrD_C_2 PF13538.6 KND94654.1 - 0.032 14.1 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 KND94654.1 - 0.04 13.9 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KND94654.1 - 0.044 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.7 KND94654.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.15 KND94654.1 - 0.073 13.0 0.6 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 NTPase PIF1 PF05970.14 KND94654.1 - 0.093 11.9 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase MbeD_MobD PF04899.12 KND94655.1 - 0.15 12.1 0.9 19 5.4 0.1 2.3 2 0 0 2 2 2 0 MbeD/MobD like Peptidase_M3 PF01432.20 KND94656.1 - 2.3e-119 399.7 0.0 3.1e-119 399.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KND94656.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Topoisom_I PF01028.20 KND94657.1 - 7e-98 326.5 7.5 7e-98 326.5 7.5 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KND94657.1 - 2.8e-92 308.1 4.0 2.8e-92 308.1 4.0 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KND94657.1 - 1e-30 105.4 0.5 1e-30 105.4 0.5 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Glyco_hydro_16 PF00722.21 KND94658.1 - 9.3e-41 139.2 0.2 1.5e-40 138.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PEPcase PF00311.17 KND94658.1 - 0.32 9.0 0.1 0.43 8.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase zf-C2H2 PF00096.26 KND94659.1 - 5.7e-13 48.5 10.9 1.8e-06 28.1 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND94659.1 - 1.6e-08 34.6 11.3 1.9e-07 31.2 4.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND94659.1 - 3.5e-08 33.6 9.3 0.0018 18.9 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KND94659.1 - 4.3e-07 30.1 3.9 0.0001 22.6 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND94659.1 - 4.1e-06 26.9 4.4 0.0014 18.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KND94659.1 - 0.00036 20.5 9.4 0.0047 16.9 0.5 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KND94659.1 - 0.003 17.2 3.4 0.4 10.3 0.2 2.5 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 KND94659.1 - 0.026 14.6 1.4 0.026 14.6 1.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf_UBZ PF18439.1 KND94659.1 - 0.062 12.9 2.0 2.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KND94659.1 - 0.19 12.4 2.6 2.9 8.6 0.4 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 KND94659.1 - 0.32 10.8 5.7 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 KND94659.1 - 1.8 8.7 5.6 9.5 6.4 0.8 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-CHY PF05495.12 KND94659.1 - 4.7 7.8 6.3 3.6 8.1 3.1 2.2 2 0 0 2 2 2 0 CHY zinc finger zf-C2HC_2 PF13913.6 KND94659.1 - 7 6.7 8.0 6 6.9 2.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 KND94659.1 - 7.9 7.0 7.3 85 3.7 7.3 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 KND94659.1 - 9.2 6.4 6.8 23 5.1 1.7 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Diphthami_syn_2 PF01902.17 KND94660.1 - 1.1e-22 80.6 0.0 2.7e-14 53.2 0.0 4.1 2 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KND94660.1 - 1.3e-11 44.5 0.0 1.1e-06 28.7 0.0 3.2 3 0 0 3 3 3 2 Endoribonuclease L-PSP Sec1 PF00995.23 KND94661.1 - 2.8e-120 403.3 0.0 4e-120 402.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.24 KND94661.1 - 3.6e-80 270.5 0.0 6.7e-79 266.3 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 KND94661.1 - 1.5e-13 50.9 0.0 3.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KND94661.1 - 9.9e-08 32.3 2.5 9.9e-08 32.3 2.5 2.4 1 1 1 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 KND94661.1 - 1.2e-07 31.8 0.1 5.2e-07 29.8 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 KND94661.1 - 2.7e-07 31.1 1.9 7.1e-07 29.7 1.9 1.7 1 0 0 1 1 1 1 HMG-box domain DAO PF01266.24 KND94661.1 - 0.004 16.8 0.3 0.012 15.2 0.3 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND94661.1 - 0.01 15.1 0.4 0.074 12.3 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ATP-synt PF00231.19 KND94662.1 - 1.1e-79 268.0 5.5 1.4e-79 267.7 5.5 1.0 1 0 0 1 1 1 1 ATP synthase KAR9 PF08580.10 KND94664.1 - 1.2e-179 599.1 1.4 1.2e-179 599.1 1.4 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.11 KND94664.1 - 0.42 11.2 10.8 2.4 8.8 0.2 4.6 3 1 0 4 4 4 0 Syntaxin 6, N-terminal CdvA PF18822.1 KND94664.1 - 7.9 6.3 7.8 20 5.0 0.0 3.6 4 0 0 4 4 4 0 CdvA-like coiled-coil domain DEAD PF00270.29 KND94665.1 - 1.6e-21 76.9 0.0 3.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94665.1 - 2e-17 63.5 0.0 4e-14 52.9 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KND94665.1 - 4.4e-16 59.4 3.5 1.4e-15 57.7 3.5 2.0 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KND94665.1 - 3.3e-12 46.2 0.1 6.8e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 KND94665.1 - 7.5e-10 39.1 0.2 3.2e-09 37.0 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 KND94665.1 - 0.0025 17.1 0.0 0.0068 15.7 0.0 1.6 1 0 0 1 1 1 1 SecA DEAD-like domain XPC-binding PF09280.11 KND94665.1 - 0.0043 16.7 3.0 0.11 12.2 1.2 2.9 2 1 0 2 2 2 1 XPC-binding domain HRDC PF00570.23 KND94665.1 - 0.0086 16.0 1.1 0.034 14.1 0.1 2.6 3 0 0 3 3 3 1 HRDC domain ChaC PF04752.12 KND94665.1 - 0.16 12.0 0.3 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 ChaC-like protein DUF1275 PF06912.11 KND94666.1 - 2.9e-39 135.0 13.1 3.6e-39 134.7 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Hairy_orange PF07527.13 KND94666.1 - 0.07 13.3 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange DUF4131 PF13567.6 KND94666.1 - 1.9 8.1 12.6 1.5 8.5 4.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 7tm_2 PF00002.24 KND94668.1 - 0.0003 20.1 15.4 0.0012 18.2 15.4 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Haemocyan_bet_s PF14830.6 KND94668.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Haemocyanin beta-sandwich DUF4181 PF13789.6 KND94668.1 - 0.32 11.3 6.7 1.3 9.4 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) Pox_A14 PF05767.12 KND94668.1 - 0.44 10.7 5.4 0.65 10.2 0.3 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Cellulase PF00150.18 KND94669.1 - 6.9e-34 117.6 0.0 8.3e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.10 KND94670.1 - 1.6e-19 69.6 0.0 5.8e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 CRT10 Ammonium_transp PF00909.21 KND94672.1 - 6.5e-118 393.9 30.5 7.5e-118 393.7 30.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.8 KND94672.1 - 3.1 7.9 7.6 15 5.7 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) ECH_1 PF00378.20 KND94673.1 - 3.5e-74 249.3 0.2 4.4e-74 249.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND94673.1 - 3.5e-34 118.8 0.4 2.8e-31 109.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PALP PF00291.25 KND94675.1 - 1.1e-64 218.7 0.2 1.6e-64 218.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 KND94675.1 - 2.5e-06 27.3 1.4 2.5e-06 27.3 1.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 KND94675.1 - 1.5e-05 24.5 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-C3HC4_2 PF13923.6 KND94675.1 - 1.9e-05 24.4 1.0 1.9e-05 24.4 1.0 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND94675.1 - 2.2e-05 24.4 1.5 2.2e-05 24.4 1.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger SH3_9 PF14604.6 KND94675.1 - 4.8e-05 23.1 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-RING_2 PF13639.6 KND94675.1 - 0.00094 19.5 2.4 0.00094 19.5 2.4 2.8 3 0 0 3 3 2 1 Ring finger domain zf-RING_5 PF14634.6 KND94675.1 - 0.0036 17.2 1.5 0.0036 17.2 1.5 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KND94675.1 - 0.0067 16.6 3.2 0.0067 16.6 3.2 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 KND94675.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ZZ PF00569.17 KND94675.1 - 3.4 7.5 14.8 2.3 8.1 0.1 3.2 4 0 0 4 4 4 0 Zinc finger, ZZ type Proteasome PF00227.26 KND94677.1 - 3.6e-41 140.8 0.7 8.5e-39 133.0 0.7 2.1 1 1 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KND94677.1 - 7.9e-13 47.6 0.1 7.9e-13 47.6 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Ribosomal_L19 PF01245.20 KND94678.1 - 1.4e-11 44.3 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Sel1 PF08238.12 KND94679.1 - 1.1e-11 45.0 5.9 0.0063 17.2 0.4 3.8 3 0 0 3 3 3 3 Sel1 repeat Anillin PF08174.11 KND94680.1 - 1.4e-11 45.0 0.0 3.7e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KND94680.1 - 7.3e-09 36.1 0.0 2.1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KND94680.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain CDC45 PF02724.14 KND94680.1 - 5.6 5.1 8.3 9.9 4.3 8.3 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_A_bac PF01000.26 KND94681.1 - 7.5e-26 90.7 0.0 1.6e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KND94681.1 - 3.9e-21 74.3 0.0 5.5e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ANAPC4_WD40 PF12894.7 KND94682.1 - 6.8e-06 26.3 0.0 7.6e-05 22.9 0.0 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NUP214 PF16755.5 KND94682.1 - 7.7e-05 22.1 0.0 0.00026 20.4 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 WD40 PF00400.32 KND94682.1 - 0.17 12.8 1.0 0.55 11.2 0.2 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat STE PF02200.16 KND94683.1 - 2.9e-56 188.6 0.1 4.7e-56 187.9 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KND94683.1 - 0.00092 19.5 4.2 0.0024 18.2 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND94683.1 - 0.042 14.7 3.1 0.12 13.3 3.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger CorA PF01544.18 KND94684.1 - 3.8e-38 131.5 0.2 1.3e-37 129.7 0.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1899 PF08953.11 KND94685.1 - 1.8e-34 117.4 0.0 3.8e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 KND94685.1 - 3.9e-18 65.1 0.4 8.8e-18 63.9 0.4 1.7 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 KND94685.1 - 4e-15 56.0 7.8 0.0022 18.8 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94685.1 - 5.2e-07 29.9 0.1 0.0019 18.5 0.2 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND94685.1 - 0.0035 16.1 0.0 0.28 9.8 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SlyX PF04102.12 KND94685.1 - 1.3 9.7 5.6 0.69 10.6 1.9 2.2 2 0 0 2 2 2 0 SlyX CBF PF03914.17 KND94686.1 - 2.8e-35 121.9 4.0 5.3e-35 121.0 1.3 2.5 2 1 1 3 3 3 1 CBF/Mak21 family COPIIcoated_ERV PF07970.12 KND94687.1 - 1.2e-87 293.5 0.0 2e-87 292.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KND94687.1 - 7.1e-30 103.2 0.0 1.6e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.6 KND94688.1 - 1.2e-32 112.2 4.3 3.3e-32 110.8 1.0 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KND94688.1 - 3.8e-21 74.7 0.0 5.7e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KND94688.1 - 1.5e-11 43.6 3.8 1.5e-11 43.6 3.8 3.5 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 KND94688.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 KND94688.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 Telomere_reg-2 PF10193.9 KND94689.1 - 1.1e-36 125.6 0.0 5.6e-36 123.3 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.21 KND94690.1 - 6.5e-55 186.1 0.9 3.3e-46 157.6 0.1 2.2 2 0 0 2 2 2 2 ThiF family E2_bind PF08825.10 KND94690.1 - 4.1e-29 100.6 0.2 7.1e-29 99.8 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 KND94690.1 - 0.017 15.7 0.2 0.048 14.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_9 PF13454.6 KND94690.1 - 0.16 11.9 0.4 1.1 9.2 0.1 2.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding E1_UFD PF09358.10 KND94690.1 - 0.19 12.4 0.0 0.68 10.7 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin fold domain Pkinase PF00069.25 KND94691.1 - 3.7e-49 167.5 0.0 5e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94691.1 - 4.3e-28 98.3 0.0 5.6e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND94691.1 - 0.0039 16.5 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND94691.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KND94691.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FLYWCH_u PF16662.5 KND94692.1 - 0.25 11.4 5.6 3.1 7.9 0.6 2.6 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 EST1_DNA_bind PF10373.9 KND94693.1 - 1e-41 143.3 0.8 1e-41 143.3 0.8 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KND94693.1 - 1.7e-23 83.8 0.3 7e-23 81.8 0.1 2.2 3 0 0 3 3 3 1 Telomerase activating protein Est1 PfkB PF00294.24 KND94694.1 - 5e-65 219.8 0.0 5.6e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase G10 PF01125.17 KND94695.1 - 1.3e-61 206.7 3.0 1.4e-61 206.5 3.0 1.0 1 0 0 1 1 1 1 G10 protein Ribosomal_L10 PF00466.20 KND94697.1 - 1.2e-20 73.5 0.0 1.9e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KND94697.1 - 5.9e-20 71.0 0.0 9.6e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P U1snRNP70_N PF12220.8 KND94698.1 - 2.2e-25 89.1 3.4 4.6e-25 88.1 3.4 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KND94698.1 - 4.8e-16 58.3 0.1 2e-15 56.3 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KND94698.1 - 7.9e-06 25.9 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 KND94699.1 - 3e-14 52.7 0.0 6.5e-14 51.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 KND94700.1 - 1.9e-85 286.1 0.2 2.3e-85 285.9 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-C2H2 PF00096.26 KND94701.1 - 0.0012 19.2 0.7 0.95 10.0 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND94701.1 - 0.0066 17.2 1.8 7.7 7.6 0.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF753 PF05444.12 KND94701.1 - 0.17 11.9 2.5 0.32 11.0 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF753) BURP PF03181.15 KND94702.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 BURP domain Zn_clus PF00172.18 KND94703.1 - 0.00035 20.6 13.0 0.00062 19.8 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF543 PF04418.12 KND94705.1 - 1.4e-29 101.9 0.0 1.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 KND94706.1 - 4.6e-63 212.9 3.1 4.8e-63 212.8 0.8 2.3 2 0 0 2 2 2 1 Urb2/Npa2 family Abhydrolase_6 PF12697.7 KND94707.1 - 0.013 16.2 2.1 0.028 15.0 2.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 KND94708.1 - 9e-41 139.5 0.0 1.3e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND94708.1 - 1.3e-22 80.6 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND94708.1 - 5.5e-07 29.7 0.0 7.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KND94708.1 - 0.00082 19.9 0.3 0.0016 19.0 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KND94708.1 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KND94708.1 - 0.0049 16.9 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 KND94708.1 - 0.0052 15.9 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KND94708.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase VIR_N PF15912.5 KND94709.1 - 0.16 11.5 1.1 0.2 11.2 1.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Pkinase PF00069.25 KND94710.1 - 1.8e-26 93.1 0.0 1.2e-13 51.0 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND94710.1 - 6.6e-05 22.3 0.1 0.048 13.0 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase GST_N_2 PF13409.6 KND94711.1 - 3.4e-23 81.7 0.0 6.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KND94711.1 - 7.1e-18 64.4 0.1 1.9e-17 63.0 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KND94711.1 - 1.8e-08 34.5 0.0 3.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KND94711.1 - 2.1e-06 27.8 0.1 4.3e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KND94711.1 - 9.2e-06 26.0 0.0 7.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KND94711.1 - 0.066 13.0 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-LYAR PF08790.11 KND94712.1 - 7e-09 35.4 0.7 1.8e-08 34.1 0.7 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Menin PF05053.13 KND94712.1 - 0.089 11.1 5.1 0.016 13.6 0.4 1.8 2 0 0 2 2 2 0 Menin Pex2_Pex12 PF04757.14 KND94713.1 - 1.9e-40 138.9 2.7 2.3e-40 138.6 2.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KND94713.1 - 3.8e-12 45.8 8.5 5.7e-12 45.3 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KND94713.1 - 1.4e-11 44.6 8.7 2e-11 44.0 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 KND94713.1 - 1.5e-10 40.8 6.6 2.2e-10 40.2 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KND94713.1 - 5.7e-10 38.9 6.5 8.6e-10 38.3 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND94713.1 - 4.5e-08 33.0 6.7 8.5e-08 32.1 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND94713.1 - 2.2e-07 30.7 5.5 3.6e-07 30.0 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KND94713.1 - 2.5e-07 30.9 6.4 4.2e-07 30.1 6.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KND94713.1 - 3.2e-07 30.1 6.7 5e-07 29.5 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KND94713.1 - 1e-06 28.7 7.6 1.7e-06 28.1 7.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KND94713.1 - 0.00025 21.1 5.2 0.0004 20.5 5.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KND94713.1 - 0.00031 20.6 1.9 0.00059 19.6 1.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 KND94713.1 - 0.003 17.3 1.1 0.0055 16.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KND94713.1 - 0.024 14.7 2.6 0.042 13.9 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KND94713.1 - 0.051 13.4 6.7 0.11 12.3 6.7 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KND94713.1 - 0.15 11.9 3.3 0.32 10.8 3.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger R3H PF01424.22 KND94714.1 - 9.5e-14 51.1 0.1 1.6e-13 50.4 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KND94714.1 - 0.00043 20.3 16.3 0.00043 20.3 16.3 12.1 11 3 2 13 13 13 3 NF-X1 type zinc finger Hydrolase_4 PF12146.8 KND94715.1 - 1.5e-12 47.3 0.0 1.7e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KND94715.1 - 3.6e-05 23.3 0.0 0.00066 19.2 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KND94715.1 - 0.00019 21.2 0.2 0.044 13.4 0.0 2.5 2 1 0 3 3 3 2 alpha/beta hydrolase fold FSH1 PF03959.13 KND94715.1 - 0.00021 21.0 0.0 0.00062 19.5 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 KND94715.1 - 0.00092 18.8 0.0 0.76 9.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.12 KND94715.1 - 0.0015 17.3 0.0 1 8.0 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KND94715.1 - 0.0035 17.2 0.0 0.61 9.9 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KND94715.1 - 0.25 11.1 0.8 8.2 6.1 0.1 2.4 2 1 1 3 3 3 0 PGAP1-like protein WSC PF01822.19 KND94716.1 - 9.5e-70 230.8 69.9 8e-19 67.6 12.9 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KND94716.1 - 3.1e-27 95.3 0.0 7.2e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KND94716.1 - 1.9e-22 79.4 0.0 3.5e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) MPC PF03650.13 KND94718.1 - 2.1e-36 124.4 0.0 2.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Translin PF01997.16 KND94718.1 - 0.16 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Translin family COesterase PF00135.28 KND94719.1 - 0.00074 18.5 0.0 0.00083 18.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Alpha_E2_glycop PF00943.19 KND94719.1 - 0.0058 15.4 0.0 0.0078 15.0 0.0 1.1 1 0 0 1 1 1 1 Alphavirus E2 glycoprotein CPSase_L_D2 PF02786.17 KND94721.1 - 5.9e-81 271.0 0.3 9.8e-81 270.3 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KND94721.1 - 7.9e-69 231.4 0.0 1.4e-68 230.6 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KND94721.1 - 1.3e-38 131.9 0.0 2.6e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KND94721.1 - 1.1e-31 109.1 0.0 4.5e-31 107.2 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KND94721.1 - 1.6e-26 93.5 0.0 3.2e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KND94721.1 - 3.8e-19 68.3 1.0 1e-18 66.9 1.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KND94721.1 - 1.4e-11 44.0 0.2 2.4e-06 27.3 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KND94721.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KND94721.1 - 3.9e-08 33.1 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KND94721.1 - 7e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KND94721.1 - 0.00013 21.3 0.1 0.043 13.0 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 KND94721.1 - 0.00014 21.5 0.0 0.00056 19.5 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 KND94721.1 - 0.00048 20.8 0.1 3.2 8.5 0.0 3.3 4 0 0 4 4 2 2 HlyD family secretion protein ATP-grasp_4 PF13535.6 KND94721.1 - 0.0048 16.5 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.9 KND94721.1 - 0.0098 15.9 0.4 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) ATPgrasp_ST PF14397.6 KND94721.1 - 0.02 14.1 0.0 0.094 11.9 0.0 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 KND94721.1 - 0.021 14.6 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 KND94721.1 - 0.021 14.2 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 KND94721.1 - 0.073 13.0 0.3 0.22 11.5 0.3 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 KND94721.1 - 0.22 11.4 0.5 0.65 9.9 0.2 1.9 2 0 0 2 2 1 0 Glycine cleavage H-protein Metallophos PF00149.28 KND94722.1 - 1e-39 137.1 0.1 2.6e-39 135.8 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KND94722.1 - 5.4e-23 81.2 1.0 1.2e-22 80.0 1.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Mito_fiss_reg PF05308.11 KND94722.1 - 0.56 10.3 3.1 1.1 9.3 3.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Catalase PF00199.19 KND94723.1 - 8.6e-194 643.9 0.6 1.1e-193 643.6 0.6 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KND94723.1 - 9.3e-11 41.8 0.0 2.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive zf-CCCH PF00642.24 KND94725.1 - 1.2e-08 34.6 18.6 5.3e-07 29.4 2.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KND94725.1 - 0.0025 17.6 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 KND94725.1 - 0.0089 16.7 3.4 0.4 11.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KND94725.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 KND94725.1 - 0.38 11.0 0.2 0.38 11.0 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 KND94726.1 - 1.1e-72 244.9 0.1 9.7e-63 212.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Peptidase_S8 PF00082.22 KND94727.1 - 3.2e-38 131.7 3.5 6e-38 130.8 3.6 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KND94727.1 - 3e-12 47.0 0.1 1.5e-11 44.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF2922 PF11148.8 KND94727.1 - 0.18 11.5 2.4 3.9 7.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2922) zf-GRF PF06839.12 KND94728.1 - 1.3e-05 25.1 5.7 2.6e-05 24.2 5.7 1.5 1 0 0 1 1 1 1 GRF zinc finger zf-C4_Topoisom PF01396.19 KND94728.1 - 0.0049 16.6 0.3 0.0087 15.8 0.3 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Prefoldin_2 PF01920.20 KND94728.1 - 0.078 12.9 1.3 0.12 12.3 1.3 1.2 1 0 0 1 1 1 0 Prefoldin subunit TMF_DNA_bd PF12329.8 KND94728.1 - 0.37 10.8 2.5 0.64 10.1 2.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DnaJ PF00226.31 KND94729.1 - 1.9e-10 40.7 1.0 6.3e-10 39.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Ada3 PF10198.9 KND94729.1 - 6.5 6.9 9.2 0.44 10.7 0.3 2.4 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 RAMP4 PF06624.12 KND94729.1 - 7.3 6.7 6.0 60 3.8 2.8 2.8 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 DUF2235 PF09994.9 KND94731.1 - 5.3e-64 216.3 0.0 7.8e-44 150.1 0.0 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3605 PF12239.8 KND94733.1 - 1.3e-55 187.9 0.1 1.6e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KND94734.1 - 2.6e-12 47.3 0.0 5.2e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase Pkinase PF00069.25 KND94735.1 - 2.2e-55 187.9 0.0 2.9e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94735.1 - 1.2e-42 146.0 0.0 1.7e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND94735.1 - 0.0023 16.9 0.1 0.14 11.0 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 KND94735.1 - 0.0028 17.0 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like ABC1 PF03109.16 KND94735.1 - 0.07 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family zf_UBZ PF18439.1 KND94736.1 - 0.63 9.7 3.3 26 4.5 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Aldo_ket_red PF00248.21 KND94737.1 - 7.2e-49 166.6 0.0 3.1e-46 157.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HRDC PF00570.23 KND94737.1 - 0.061 13.3 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 HRDC domain DRMBL PF07522.14 KND94738.1 - 2.1e-34 118.0 0.0 3.9e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KND94738.1 - 3.1e-07 30.1 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AMP-binding PF00501.28 KND94739.1 - 1.2e-71 241.6 0.0 1.4e-71 241.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KND94739.1 - 6.7e-20 71.9 0.2 1.4e-19 70.8 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ifi-6-16 PF06140.13 KND94739.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 6-16 family LSM PF01423.22 KND94740.1 - 3.2e-18 65.2 0.3 4.1e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KND94740.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Hfq protein AEP1 PF17049.5 KND94740.1 - 0.026 13.6 0.1 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 SM-ATX PF14438.6 KND94740.1 - 0.052 13.7 0.0 0.07 13.3 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain WD40 PF00400.32 KND94741.1 - 3.3e-47 157.5 31.5 1.9e-07 31.6 0.3 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 KND94741.1 - 1.4e-17 64.0 0.2 2.8e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KND94741.1 - 1.5e-17 63.7 6.1 0.066 13.5 0.1 8.9 5 2 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KND94741.1 - 3.7e-06 26.5 0.0 0.21 10.9 0.0 4.2 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 KND94741.1 - 4.5e-06 25.6 0.9 0.83 8.2 0.1 4.7 5 1 0 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 KND94741.1 - 0.0036 17.2 0.1 0.17 11.7 0.0 3.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 KND94741.1 - 0.017 13.9 6.2 1.2 7.8 0.1 4.6 4 1 1 6 6 6 0 Nup133 N terminal like Frtz PF11768.8 KND94741.1 - 0.033 12.5 0.0 0.33 9.2 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 KND94741.1 - 0.15 11.8 0.4 5.1 6.8 0.0 3.5 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF4558 PF15104.6 KND94741.1 - 0.67 10.0 4.6 5 7.3 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) P34-Arc PF04045.14 KND94742.1 - 2.3e-104 348.4 0.6 2.7e-104 348.1 0.6 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Protamine_3 PF08188.11 KND94742.1 - 0.18 12.0 1.5 0.35 11.1 1.5 1.5 1 0 0 1 1 1 0 Spermatozal protamine family ERCC3_RAD25_C PF16203.5 KND94743.1 - 6.4e-122 405.5 0.2 1.4e-121 404.3 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KND94743.1 - 3.9e-34 117.5 0.0 2.7e-33 114.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND94743.1 - 9.7e-15 55.0 0.0 2e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KND94743.1 - 6e-12 45.9 0.1 1.5e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KND94743.1 - 2.6e-07 29.7 0.0 3.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Biotin_lipoyl_2 PF13533.6 KND94743.1 - 0.12 12.2 2.0 0.3 11.0 2.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like SNase PF00565.17 KND94744.1 - 3.1e-26 92.0 0.0 4.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue zf-CHY PF05495.12 KND94745.1 - 2.5e-12 47.1 16.5 5.6e-12 46.0 16.5 1.5 1 1 0 1 1 1 1 CHY zinc finger zf-RRPl_C4 PF17026.5 KND94745.1 - 0.0036 17.4 1.8 0.0036 17.4 1.8 2.0 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type RNA_POL_M_15KD PF02150.16 KND94745.1 - 0.097 12.6 10.8 3.2 7.7 1.3 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 KND94745.1 - 3.5 7.7 12.2 17 5.5 12.2 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_4 PF07975.12 KND94745.1 - 10 6.5 17.3 3.3 8.0 0.6 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain Rax2 PF12768.7 KND94746.1 - 2.5e-77 259.2 0.9 3.1e-76 255.6 0.1 3.0 3 0 0 3 3 3 1 Cortical protein marker for cell polarity stn_TNFRSF12A PF12191.8 KND94746.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LapA_dom PF06305.11 KND94746.1 - 0.17 11.8 0.3 0.33 10.8 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TrkH PF02386.16 KND94747.1 - 4.3e-132 441.1 0.2 6.7e-132 440.5 0.2 1.2 1 0 0 1 1 1 1 Cation transport protein CH PF00307.31 KND94748.1 - 6.3e-47 158.3 0.1 6.5e-23 81.0 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KND94748.1 - 3.6e-26 91.1 2.8 3.2e-25 88.0 0.2 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KND94748.1 - 1e-12 47.7 0.2 9.8e-08 31.7 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KND94748.1 - 7.6e-06 25.5 0.5 0.00023 20.9 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 KND94748.1 - 0.00016 22.1 3.5 0.0006 20.2 2.9 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KND94748.1 - 0.0017 17.7 0.3 0.12 12.0 0.1 2.8 2 0 0 2 2 2 1 EF hand CH_2 PF06294.11 KND94748.1 - 0.0026 17.8 0.1 0.1 12.7 0.0 3.0 3 0 0 3 3 3 1 CH-like domain in sperm protein Spectrin PF00435.21 KND94748.1 - 0.0028 18.1 1.6 1.2 9.7 0.3 2.6 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.6 KND94748.1 - 0.0038 17.1 1.2 0.23 11.3 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair Ribonuc_2-5A PF06479.12 KND94748.1 - 0.095 12.9 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease 2-5A DUF4508 PF14969.6 KND94748.1 - 0.67 10.2 4.3 7.1 7.0 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) Proteasome PF00227.26 KND94750.1 - 1.7e-54 184.2 0.1 2.4e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KND94750.1 - 0.00014 21.5 0.6 0.0004 20.0 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FAD-oxidase_C PF02913.19 KND94751.1 - 7.5e-57 192.8 0.0 1.2e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KND94751.1 - 1.5e-34 118.7 0.5 3.1e-34 117.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain DEC-1_N PF04625.13 KND94751.1 - 0.17 10.9 2.7 0.34 9.9 2.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Zn_clus PF00172.18 KND94751.1 - 0.43 10.7 16.1 0.3 11.2 6.7 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1682 PF07946.14 KND94753.1 - 3.6e-108 361.6 0.2 4.4e-108 361.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2985 PF11204.8 KND94753.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) Sacchrp_dh_NADP PF03435.18 KND94754.1 - 2.3e-18 66.7 0.0 3.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KND94754.1 - 0.004 17.6 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KND94754.1 - 0.074 12.2 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L37ae PF01780.19 KND94755.1 - 4.6e-39 132.4 10.1 7.2e-39 131.8 10.1 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KND94755.1 - 0.00084 19.3 4.1 0.0015 18.5 4.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 KND94755.1 - 0.0067 16.5 1.0 0.01 15.9 1.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain Sgf11 PF08209.11 KND94755.1 - 0.013 15.0 0.7 0.079 12.5 0.1 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-RING_13 PF17977.1 KND94755.1 - 0.045 13.9 2.6 0.045 13.9 2.6 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KND94755.1 - 0.053 13.6 0.9 0.053 13.6 0.9 2.3 1 1 1 2 2 2 0 BED zinc finger Zn_ribbon_SprT PF17283.2 KND94755.1 - 0.091 12.7 4.2 0.24 11.3 4.2 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain C1_2 PF03107.16 KND94755.1 - 0.19 12.1 2.2 3.2 8.2 2.2 2.2 1 1 0 1 1 1 0 C1 domain A2L_zn_ribbon PF08792.10 KND94755.1 - 0.2 11.4 1.9 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 KND94755.1 - 3.2 8.4 6.3 2.4 8.7 0.8 2.5 1 1 1 2 2 2 0 Zinc-finger double domain DUF155 PF02582.14 KND94756.1 - 1.8e-52 178.0 0.3 2.6e-52 177.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF4642 PF15484.6 KND94756.1 - 0.089 13.0 0.1 0.64 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) Ank_2 PF12796.7 KND94757.1 - 3e-112 367.4 0.1 2e-16 60.3 0.0 10.3 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND94757.1 - 6.6e-84 275.3 6.0 5.4e-09 36.4 0.0 12.9 4 4 11 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND94757.1 - 5.9e-78 247.5 0.0 0.0011 19.2 0.0 19.4 19 0 0 19 19 19 17 Ankyrin repeat Ank PF00023.30 KND94757.1 - 4.8e-62 203.9 15.8 0.00082 19.7 0.0 18.3 18 0 0 18 18 18 14 Ankyrin repeat Ank_5 PF13857.6 KND94757.1 - 2.7e-58 193.2 19.9 6.6e-09 35.9 0.0 13.2 5 3 9 14 14 14 11 Ankyrin repeats (many copies) F-box-like PF12937.7 KND94757.1 - 0.00067 19.5 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 KND94757.1 - 3.8 7.5 8.1 15 5.6 0.0 5.3 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain CAF1 PF04857.20 KND94758.1 - 2e-70 237.5 0.0 2e-70 237.5 0.0 4.1 3 2 0 3 3 1 1 CAF1 family ribonuclease SMC_N PF02463.19 KND94758.1 - 8.9e-63 211.7 2.8 1.6e-62 210.8 2.8 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KND94758.1 - 2.4e-25 89.1 0.0 1.5e-24 86.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KND94758.1 - 1.8e-18 67.7 0.2 1.8e-18 67.7 0.2 6.9 2 2 4 6 6 2 1 AAA domain AAA_15 PF13175.6 KND94758.1 - 5e-17 62.7 31.1 4.9e-16 59.4 0.0 4.0 2 2 2 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 KND94758.1 - 1.4e-13 51.3 3.1 6.7e-06 26.1 0.1 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KND94758.1 - 0.0012 19.0 0.1 0.0041 17.3 0.1 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KND94758.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 KND94758.1 - 0.019 15.0 0.7 0.019 15.0 0.7 8.2 4 3 2 8 8 8 0 Laminin Domain II PCI PF01399.27 KND94758.1 - 0.3 11.6 2.7 0.63 10.6 0.3 2.9 2 0 0 2 2 2 0 PCI domain ABC_tran PF00005.27 KND94758.1 - 0.85 10.1 0.0 0.85 10.1 0.0 5.9 3 2 0 3 3 1 0 ABC transporter DUF3535 PF12054.8 KND94759.1 - 2.3e-126 422.6 2.0 3.2e-125 418.8 1.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KND94759.1 - 9.5e-66 221.9 0.1 2.6e-65 220.5 0.0 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain CDC37_N PF03234.14 KND94759.1 - 9e-49 165.7 0.1 9e-49 165.7 0.1 4.2 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KND94759.1 - 7.5e-39 132.3 1.5 1.1e-37 128.5 0.3 2.8 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KND94759.1 - 1.9e-32 111.3 3.7 1.9e-32 111.3 3.7 2.8 2 0 0 2 2 1 1 Cdc37 C terminal domain Helicase_C PF00271.31 KND94759.1 - 5.2e-19 68.6 0.0 2.5e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 KND94759.1 - 3.8e-17 60.9 1.9 0.005 17.0 0.0 7.8 7 0 0 7 7 7 4 HEAT repeat Vac14_Fab1_bd PF12755.7 KND94759.1 - 9.4e-08 32.6 0.4 0.7 10.5 0.0 4.1 3 0 0 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KND94759.1 - 1.7e-06 28.4 5.5 0.0021 18.4 0.1 5.8 6 0 0 6 6 5 1 HEAT repeats CLASP_N PF12348.8 KND94759.1 - 0.012 15.2 0.3 1.8 8.1 0.2 3.3 3 1 0 3 3 3 0 CLASP N terminal LPD39 PF18858.1 KND94759.1 - 0.031 14.4 3.3 6.8 6.7 0.2 3.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 SAPS PF04499.15 KND94759.1 - 0.064 12.0 6.9 4.4 6.0 0.0 2.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein ERCC3_RAD25_C PF16203.5 KND94759.1 - 0.072 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HEAT_EZ PF13513.6 KND94759.1 - 0.099 13.2 12.8 33 5.1 0.0 7.7 8 0 0 8 8 8 0 HEAT-like repeat MecA_N PF05223.11 KND94759.1 - 0.9 9.8 4.3 3.8 7.8 4.3 2.1 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain zf-rbx1 PF12678.7 KND94760.1 - 6.9e-10 39.1 11.5 1.4e-06 28.5 3.7 3.0 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KND94760.1 - 3.6e-09 36.8 19.1 1.6e-07 31.5 0.9 3.6 3 1 0 3 3 3 2 Ring finger domain PHD PF00628.29 KND94760.1 - 2.4e-08 33.8 6.6 2.4e-08 33.8 6.6 2.7 2 1 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 KND94760.1 - 4.1e-06 26.3 3.0 4.1e-06 26.3 3.0 2.3 2 0 0 2 2 2 1 PHD-finger zf-C3HC4 PF00097.25 KND94760.1 - 7.9e-06 25.7 0.1 7.9e-06 25.7 0.1 2.8 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND94760.1 - 3.7e-05 23.5 1.5 3.7e-05 23.5 1.5 2.8 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KND94760.1 - 0.00018 21.5 8.8 0.0041 17.1 0.3 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KND94760.1 - 0.00034 20.5 0.8 0.00034 20.5 0.8 3.5 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KND94760.1 - 0.0004 20.2 0.8 0.0004 20.2 0.8 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND94760.1 - 0.00091 18.8 1.7 0.00091 18.8 1.7 2.7 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KND94760.1 - 0.0038 17.1 1.0 0.0038 17.1 1.0 3.7 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 KND94760.1 - 0.0068 16.3 2.5 0.0068 16.3 2.5 2.7 3 0 0 3 3 2 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KND94760.1 - 0.049 13.3 4.0 0.069 12.8 1.2 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CTU2 PF10288.9 KND94760.1 - 0.26 11.5 2.3 3 8.1 2.3 2.8 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PHD_3 PF13922.6 KND94760.1 - 0.77 10.2 6.1 1.6 9.1 1.7 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_9 PF13901.6 KND94760.1 - 0.81 9.6 8.7 5.1 7.0 0.5 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon C1_1 PF00130.22 KND94760.1 - 5.6 6.9 7.2 3.9 7.4 0.3 3.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_6 PF14835.6 KND94760.1 - 6.8 6.6 7.7 0.14 12.1 0.3 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.11 KND94760.1 - 9 6.7 15.6 0.79 10.1 2.5 2.5 2 0 0 2 2 2 0 RING-like domain MRP-L46 PF11788.8 KND94761.1 - 1.1e-26 94.0 0.0 1.9e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KND94761.1 - 0.023 14.7 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 NUDIX domain VTC PF09359.10 KND94762.1 - 2.9e-100 335.2 0.6 3.7e-100 334.9 0.0 1.5 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 KND94762.1 - 1.6e-13 50.9 2.7 3e-13 50.0 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KND94762.1 - 2.8e-10 40.7 8.0 1.1e-05 25.5 0.0 3.3 3 1 1 4 4 4 2 SPX domain TrmB PF01978.19 KND94762.1 - 0.028 14.3 0.1 0.09 12.7 0.1 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 KND94762.1 - 0.061 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain 7TMR-DISM_7TM PF07695.11 KND94762.1 - 0.31 10.9 4.2 0.48 10.3 4.2 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling MCM PF00493.23 KND94763.1 - 4.1e-100 333.5 0.0 6e-100 332.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KND94763.1 - 3.9e-37 126.9 2.1 7.2e-37 126.0 2.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KND94763.1 - 1.2e-27 96.2 2.9 2.6e-27 95.1 2.9 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND94763.1 - 2.5e-18 66.6 0.1 7.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND94763.1 - 5.4e-05 22.7 0.0 0.00066 19.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND94763.1 - 9.2e-05 22.5 0.1 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KND94763.1 - 0.0023 17.8 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) GGA_N-GAT PF18308.1 KND94763.1 - 0.28 10.9 0.0 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 GGA N-GAT domain Rad21_Rec8_N PF04825.13 KND94764.1 - 5.4e-38 129.6 0.0 1e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KND94764.1 - 4.4e-09 35.5 0.1 9.6e-09 34.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein THOC7 PF05615.13 KND94765.1 - 3e-45 153.7 3.1 3e-45 153.7 3.1 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 CCDC144C PF14915.6 KND94765.1 - 0.067 12.3 12.4 0.098 11.8 12.4 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region TMEM247 PF15444.6 KND94765.1 - 0.083 12.9 0.0 0.083 12.9 0.0 2.7 1 1 0 3 3 3 0 Transmembrane protein 247 FUSC PF04632.12 KND94765.1 - 0.13 10.8 8.2 0.18 10.3 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 KND94765.1 - 0.42 10.9 9.5 1.2 9.5 9.5 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 KND94765.1 - 0.91 8.8 8.5 1.4 8.2 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 KND94765.1 - 1.1 9.9 5.6 13 6.5 1.4 2.4 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 KND94765.1 - 1.4 9.1 9.4 3.8 7.7 0.5 2.5 2 0 0 2 2 2 0 bZIP transcription factor zf-CCCH PF00642.24 KND94768.1 - 1.9e-11 43.6 21.3 6.4e-06 25.9 1.2 4.4 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KND94768.1 - 1e-06 28.6 27.0 0.00088 19.2 1.2 4.4 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_4 PF18044.1 KND94768.1 - 3.8e-05 23.4 4.1 0.0043 16.8 0.5 3.4 4 0 0 4 4 4 2 CCCH-type zinc finger zf-C3H1 PF10650.9 KND94768.1 - 0.0013 18.4 4.3 0.036 13.8 0.1 3.1 2 0 0 2 2 2 1 Putative zinc-finger domain Torus PF16131.5 KND94768.1 - 0.044 14.5 20.3 0.07 13.8 0.2 4.2 2 1 3 5 5 5 0 Torus domain zf-CCCH_3 PF15663.5 KND94768.1 - 0.14 12.4 11.1 0.14 12.4 0.5 3.3 3 1 0 3 3 3 0 Zinc-finger containing family Sua5_yciO_yrdC PF01300.18 KND94769.1 - 2.2e-53 180.4 0.0 3.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KND94769.1 - 5.5e-31 107.9 0.0 8.2e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.20 KND94770.1 - 2.6e-15 56.6 1.0 3.7e-14 52.9 1.0 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain COG4 PF08318.12 KND94771.1 - 4.6e-124 413.9 0.0 6.1e-124 413.5 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HSCB_C PF07743.13 KND94771.1 - 0.019 15.4 8.0 0.065 13.7 0.6 3.9 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain DUF2379 PF09543.10 KND94771.1 - 0.043 14.0 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Cation_ATPase_C PF00689.21 KND94772.1 - 4.5e-46 156.9 1.0 8.4e-46 156.0 1.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KND94772.1 - 1.6e-45 154.9 0.3 5e-45 153.2 0.3 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KND94772.1 - 4.6e-23 82.6 0.1 4.2e-22 79.5 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KND94772.1 - 1.3e-18 66.4 0.0 2.8e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KND94772.1 - 1.2e-11 44.5 0.0 2.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KND94772.1 - 0.00022 21.0 0.3 0.00022 21.0 0.3 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VPS9 PF02204.18 KND94773.1 - 2.2e-24 85.6 0.0 4e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5401 PF17380.2 KND94773.1 - 1.3 7.0 5.2 2 6.4 5.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AA_kinase PF00696.28 KND94775.1 - 6.1e-39 134.0 0.8 8.1e-39 133.6 0.8 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KND94775.1 - 4.9e-17 61.7 1.4 2.4e-16 59.5 0.2 2.3 2 0 0 2 2 2 1 PUA domain HGTP_anticodon PF03129.20 KND94776.1 - 2.8e-23 81.9 0.7 3e-21 75.3 0.0 3.4 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KND94776.1 - 7.9e-09 35.7 0.0 9.4e-08 32.2 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SNF5 PF04855.12 KND94777.1 - 3.5e-65 220.1 0.1 6.2e-64 216.0 0.1 2.5 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 KND94777.1 - 0.00047 20.2 3.8 0.00047 20.2 3.8 3.2 2 1 1 3 3 3 2 INO80 complex subunit Ies4 HEAT PF02985.22 KND94778.1 - 0.00039 20.5 0.1 0.24 11.8 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KND94778.1 - 0.0034 17.9 4.2 0.019 15.5 0.0 4.4 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KND94778.1 - 0.029 14.7 3.0 0.7 10.3 0.1 4.3 5 0 0 5 5 5 0 HEAT repeats Nitr_red_assoc PF09655.10 KND94778.1 - 0.087 13.5 2.2 6.7 7.3 0.0 3.3 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) mRNA_cap_enzyme PF01331.19 KND94780.1 - 3.1e-54 183.8 0.1 4.1e-54 183.4 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KND94780.1 - 2.8e-34 118.0 0.2 5.1e-34 117.2 0.2 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KND94780.1 - 5e-08 32.8 0.0 1.6e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 KND94780.1 - 0.0002 21.7 0.0 0.00032 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Vip3A_N PF12495.8 KND94780.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Pkinase PF00069.25 KND94781.1 - 7.1e-68 228.8 2.3 7.1e-68 228.8 2.3 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94781.1 - 5.8e-53 179.8 0.1 1.2e-52 178.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KND94781.1 - 7.7e-24 83.8 0.0 2.5e-23 82.2 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.6 KND94781.1 - 5.9e-06 26.6 0.1 2e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 KND94781.1 - 1.4e-05 24.6 0.0 1.4e-05 24.6 0.0 1.6 2 0 0 2 2 1 1 Kinase-like Pkinase_fungal PF17667.1 KND94781.1 - 5.8e-05 22.0 0.0 5.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 KND94781.1 - 0.0035 17.8 0.1 0.0087 16.6 0.1 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 KND94781.1 - 0.0045 16.0 0.9 0.0045 16.0 0.9 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KND94781.1 - 0.015 14.7 0.1 0.033 13.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND94781.1 - 0.017 15.0 0.2 0.017 15.0 0.2 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family DDRGK PF09756.9 KND94781.1 - 4.4 6.9 13.5 10 5.7 13.5 1.5 1 0 0 1 1 1 0 DDRGK domain PUF PF00806.19 KND94782.1 - 2.9e-26 89.6 0.0 0.00012 21.5 0.0 6.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 KND94782.1 - 1.4e-13 50.5 0.0 2.8e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 KND94783.1 - 3.7e-15 55.5 20.0 5.1e-09 35.9 10.2 2.4 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 KND94783.1 - 0.0045 16.8 11.3 0.35 10.8 2.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KND94783.1 - 0.13 12.6 12.7 0.59 10.5 1.0 2.6 2 0 0 2 2 2 0 C1 domain zf-PHD-like PF15446.6 KND94783.1 - 0.38 10.3 8.7 0.93 9.1 2.2 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KND94783.1 - 0.81 9.3 15.6 0.076 12.6 5.2 3.1 3 0 0 3 3 3 0 PHD-finger Zf_RING PF16744.5 KND94783.1 - 1.7 8.8 14.2 0.42 10.8 1.1 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 KND94783.1 - 5.8 7.1 18.9 11 6.1 2.4 2.8 2 0 0 2 2 2 0 PHD-finger Peptidase_M24 PF00557.24 KND94784.1 - 8.5e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 SapB_1 PF05184.15 KND94784.1 - 0.79 9.8 0.1 0.79 9.8 0.1 2.8 4 0 0 4 4 4 0 Saposin-like type B, region 1 Zn_clus PF00172.18 KND94785.1 - 2.2e-08 34.1 6.2 4.3e-08 33.1 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND94785.1 - 3.7e-06 26.0 0.4 4.9e-06 25.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Chromo PF00385.24 KND94786.1 - 1.5e-08 34.4 1.5 0.00011 22.0 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Hamartin PF04388.12 KND94786.1 - 3.6 6.1 9.6 4.8 5.7 9.6 1.1 1 0 0 1 1 1 0 Hamartin protein NOA36 PF06524.12 KND94786.1 - 6.8 5.9 13.4 10 5.3 13.4 1.4 1 0 0 1 1 1 0 NOA36 protein zf-RING_UBOX PF13445.6 KND94787.1 - 0.013 15.5 0.2 0.024 14.6 0.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Rer1 PF03248.13 KND94788.1 - 2.4e-77 258.5 8.0 2.7e-77 258.3 8.0 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 KND94788.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Paf1 PF03985.13 KND94789.1 - 2.1e-100 336.7 0.8 2.4e-100 336.5 0.8 1.0 1 0 0 1 1 1 1 Paf1 Nucleoside_tran PF01733.18 KND94790.1 - 2.6e-39 135.4 11.9 6.6e-36 124.2 11.9 2.2 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 KND94790.1 - 0.52 9.2 42.6 0.057 12.3 6.9 3.0 1 1 1 2 2 2 0 Major Facilitator Superfamily HET PF06985.11 KND94792.1 - 1.3e-19 71.0 0.0 1.8e-17 64.0 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Catalase PF00199.19 KND94793.1 - 3.5e-166 553.1 0.8 4.4e-166 552.7 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KND94793.1 - 2.2e-49 167.0 1.9 3.6e-49 166.3 1.9 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KND94793.1 - 3.3e-18 65.7 0.0 6.3e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive SYF2 PF08231.12 KND94794.1 - 8.8e-56 188.7 14.0 8.8e-56 188.7 14.0 2.7 2 1 0 3 3 3 1 SYF2 splicing factor YEATS PF03366.16 KND94795.1 - 1.9e-29 101.4 0.2 3e-29 100.8 0.2 1.3 1 0 0 1 1 1 1 YEATS family DUF641 PF04859.12 KND94795.1 - 0.11 12.9 2.0 0.14 12.5 1.2 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Ins_P5_2-kin PF06090.12 KND94797.1 - 1.2e-31 110.4 0.0 8.1e-29 101.1 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Phosphoesterase PF04185.14 KND94798.1 - 5.4e-32 111.4 1.5 1.8e-31 109.6 0.7 2.1 1 1 1 2 2 2 1 Phosphoesterase family Far-17a_AIG1 PF04750.14 KND94799.1 - 3e-43 147.5 14.6 3.4e-43 147.3 14.6 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein CPP1-like PF11833.8 KND94799.1 - 0.22 11.2 0.6 0.51 10.0 0.6 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2700 PF10912.8 KND94799.1 - 1.8 8.6 6.6 0.78 9.8 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2700) Ferritin_2 PF13668.6 KND94800.1 - 6e-45 152.8 3.7 9.3e-45 152.2 3.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4439 PF14530.6 KND94800.1 - 0.0029 18.3 0.2 0.0053 17.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4439) WD40 PF00400.32 KND94801.1 - 1.7e-08 34.9 0.0 0.35 11.8 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94801.1 - 6.3e-06 26.4 0.0 0.092 13.0 0.0 4.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Indigoidine_A PF04227.12 KND94802.1 - 9.4e-109 363.3 1.7 1.3e-108 362.8 1.7 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KND94802.1 - 3.4e-21 75.8 0.1 1.1e-13 51.2 0.0 3.0 3 1 0 3 3 3 2 pfkB family carbohydrate kinase HTH_DeoR PF08220.12 KND94802.1 - 0.26 11.1 1.0 1.7 8.5 0.5 2.6 2 1 0 2 2 2 0 DeoR-like helix-turn-helix domain FMN_dh PF01070.18 KND94803.1 - 1.4e-124 415.7 0.0 1.6e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KND94803.1 - 1.2e-07 31.5 2.6 1.9e-07 30.8 2.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KND94803.1 - 1.7e-05 24.0 1.4 0.00022 20.3 0.5 2.2 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KND94803.1 - 0.00021 20.6 0.3 0.00032 20.0 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KND94803.1 - 0.0035 16.7 2.7 0.13 11.5 1.4 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KND94803.1 - 0.013 15.0 0.6 0.045 13.2 0.5 1.8 1 1 1 2 2 2 0 Histidine biosynthesis protein SLD5_C PF16922.5 KND94804.1 - 7.1e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KND94804.1 - 8.3e-10 39.1 0.6 2.3e-09 37.7 0.4 1.8 2 1 0 2 2 2 1 GINS complex protein Calreticulin PF00262.18 KND94805.1 - 2.3e-167 556.4 16.1 3.4e-167 555.9 16.1 1.2 1 0 0 1 1 1 1 Calreticulin family EMC3_TMCO1 PF01956.16 KND94805.1 - 0.26 11.0 0.0 0.43 10.3 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like adh_short PF00106.25 KND94806.1 - 1.3e-37 129.2 0.1 1.7e-37 128.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND94806.1 - 2.8e-27 95.8 0.0 3.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND94806.1 - 1.9e-08 34.4 0.1 5e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KND94806.1 - 0.00093 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KND94806.1 - 0.069 12.2 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PapA_C PF16911.5 KND94806.1 - 0.073 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus FAD_binding_3 PF01494.19 KND94807.1 - 2.6e-75 253.8 0.0 3.2e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KND94807.1 - 1.1e-28 100.3 0.0 2.1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 KND94807.1 - 5.2e-05 23.4 0.1 0.00014 22.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KND94807.1 - 5.9e-05 22.4 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KND94807.1 - 0.0004 19.2 0.1 0.00068 18.5 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 KND94807.1 - 0.0051 15.9 0.5 0.0096 15.0 0.2 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 KND94807.1 - 0.0085 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 KND94807.1 - 0.0094 15.1 0.2 0.015 14.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KND94807.1 - 0.011 16.3 0.0 0.05 14.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KND94807.1 - 0.04 13.5 0.5 0.33 10.5 0.3 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KND94807.1 - 0.081 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A XdhC_C PF13478.6 KND94807.1 - 0.11 13.1 0.1 0.33 11.4 0.0 1.9 2 0 0 2 2 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 KND94807.1 - 0.11 11.7 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 KND94807.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KND94807.1 - 0.17 11.7 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fringe PF02434.16 KND94808.1 - 5.1e-06 26.1 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_1 PF00024.26 KND94808.1 - 0.004 17.1 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 PAN domain HGD-D PF06050.13 KND94808.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DEAD PF00270.29 KND94809.1 - 2.1e-46 157.9 0.0 4.8e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94809.1 - 1.2e-27 96.4 0.0 8.5e-27 93.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND94809.1 - 0.00086 19.4 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 KND94809.1 - 0.0046 17.5 2.8 0.0046 17.5 2.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2986) PRAI PF00697.22 KND94809.1 - 0.04 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3334 PF11813.8 KND94809.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Pkinase PF00069.25 KND94810.1 - 0.0026 17.2 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94810.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PHD PF00628.29 KND94811.1 - 1.5e-06 28.0 7.1 2.8e-06 27.1 7.1 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 KND94811.1 - 0.028 15.0 0.0 0.089 13.4 0.0 2.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 KND94811.1 - 0.094 13.0 1.7 0.19 12.0 1.7 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 KND94811.1 - 0.45 10.1 1.6 0.88 9.2 1.6 1.5 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_2 PF00703.21 KND94814.1 - 9.4e-05 23.1 0.0 0.00017 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KND94814.1 - 0.0043 16.2 0.0 0.0069 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KND94814.1 - 0.029 14.3 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain KorB PF08535.10 KND94815.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 KorB domain DUF2723 PF11028.8 KND94817.1 - 1.3 8.9 13.4 0.22 11.4 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2723) Ribosomal_L10 PF00466.20 KND94818.1 - 2.7e-22 78.8 0.2 6.7e-22 77.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 KND94818.1 - 3.3e-22 78.3 0.0 6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KND94818.1 - 3.2e-18 66.1 4.5 1.9e-17 63.6 3.9 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pkinase PF00069.25 KND94819.1 - 9.1e-76 254.7 0.0 1.8e-75 253.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94819.1 - 4.8e-37 127.6 0.0 9.8e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KND94819.1 - 3.9e-15 56.0 0.1 7.6e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain PCI PF01399.27 KND94819.1 - 4.7e-13 49.6 0.2 1.5e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 KND94819.1 - 4.3e-10 39.1 0.4 8.5e-10 38.2 0.4 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Kinase-like PF14531.6 KND94819.1 - 8e-09 35.2 0.0 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 KND94819.1 - 6.9e-08 32.7 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 KND94819.1 - 2.7e-05 23.1 0.0 5.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KND94819.1 - 0.019 14.3 0.4 0.1 12.0 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps35 PF03635.17 KND94819.1 - 0.072 11.6 0.3 1 7.7 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 ADK PF00406.22 KND94820.1 - 2.4e-45 154.4 0.0 3.7e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KND94820.1 - 1.9e-34 119.0 0.0 1.9e-34 119.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KND94820.1 - 6.1e-07 29.7 0.5 5.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KND94820.1 - 1.1e-06 29.2 0.0 2.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KND94820.1 - 0.026 14.2 3.8 2.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_22 PF13401.6 KND94820.1 - 0.13 12.5 0.4 11 6.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF3446 PF11928.8 KND94820.1 - 0.26 11.6 1.6 0.59 10.5 1.6 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain Pep1_7 PF17232.2 KND94822.1 - 0.061 13.8 1.3 0.061 13.8 1.3 2.5 3 0 0 3 3 3 0 Elicitor peptide 1-7 SR-25 PF10500.9 KND94823.1 - 0.00028 20.6 7.2 0.00028 20.6 7.2 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Cgr1 PF03879.14 KND94825.1 - 5.6e-33 113.6 28.8 6.3e-33 113.4 28.8 1.0 1 0 0 1 1 1 1 Cgr1 family RR_TM4-6 PF06459.12 KND94825.1 - 1.1 9.0 11.2 1.2 8.9 11.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-SAP30 PF13866.6 KND94825.1 - 5.4 7.2 12.1 0.12 12.5 3.5 2.3 1 1 1 2 2 2 0 SAP30 zinc-finger Silic_transp PF03842.13 KND94825.1 - 9.4 4.4 5.6 11 4.2 5.6 1.0 1 0 0 1 1 1 0 Silicon transporter IKBKB_SDD PF18397.1 KND94826.1 - 0.031 13.6 1.3 0.045 13.1 1.3 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Fib_alpha PF08702.10 KND94826.1 - 0.053 13.7 0.3 0.096 12.9 0.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 KND94826.1 - 0.097 13.1 6.2 0.11 12.8 0.9 2.6 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MSC PF09402.10 KND94826.1 - 0.1 12.1 0.8 0.15 11.5 0.8 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF1664 PF07889.12 KND94826.1 - 0.21 11.6 1.4 2.8 8.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 KND94826.1 - 0.24 11.4 3.9 0.51 10.4 0.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 KND94826.1 - 0.38 10.5 0.1 0.38 10.5 0.1 2.2 3 0 0 3 3 3 0 Septum formation initiator SelP_N PF04592.14 KND94826.1 - 1.7 8.0 13.6 3.2 7.1 13.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PTS_2-RNA PF01885.16 KND94827.1 - 5.9e-63 212.2 0.0 7e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Efg1 PF10153.9 KND94829.1 - 1.6e-27 96.1 4.1 1.6e-27 96.1 4.1 2.0 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DMAP_binding PF06464.11 KND94829.1 - 0.0024 18.6 0.2 0.0024 18.6 0.2 2.2 2 0 0 2 2 2 1 DMAP1-binding Domain dsrm PF00035.26 KND94830.1 - 0.00033 21.3 0.0 0.0019 18.8 0.0 2.3 2 1 0 2 2 2 1 Double-stranded RNA binding motif Pkinase PF00069.25 KND94831.1 - 1.3e-57 195.1 0.0 1.9e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94831.1 - 1e-20 74.1 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KND94831.1 - 4.3e-05 22.6 0.0 7.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KND94831.1 - 0.00018 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KND94831.1 - 0.0088 15.7 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KND94831.1 - 0.012 15.6 0.1 0.049 13.5 0.1 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND94831.1 - 0.036 12.8 0.0 0.082 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Bac_rhamnosid PF05592.11 KND94831.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain zinc_ribbon_16 PF17034.5 KND94832.1 - 1.3e-17 64.2 7.4 2.6e-17 63.2 7.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 KND94832.1 - 1.7e-06 27.5 4.4 1.7e-06 27.5 4.4 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-FPG_IleRS PF06827.14 KND94832.1 - 0.69 9.8 7.8 0.67 9.9 0.2 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS His_Phos_1 PF00300.22 KND94833.1 - 9.7e-17 61.3 0.0 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) LRR_6 PF13516.6 KND94834.1 - 2.2e-13 49.1 1.9 0.0068 16.4 0.0 7.4 8 0 0 8 8 8 3 Leucine Rich repeat F-box-like PF12937.7 KND94834.1 - 9e-12 44.7 0.0 3.3e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND94834.1 - 1.6e-07 31.0 0.0 5.4e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KND94834.1 - 2.9e-07 30.7 8.1 0.072 13.5 0.0 5.4 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KND94834.1 - 0.025 15.1 13.5 0.78 10.5 0.0 6.9 9 0 0 9 9 9 0 Leucine Rich Repeat PRANC PF09372.10 KND94834.1 - 0.2 12.0 0.2 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 PRANC domain UAA PF08449.11 KND94835.1 - 2.7e-43 148.3 5.9 3.9e-43 147.8 5.9 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KND94835.1 - 1.5e-09 38.2 24.8 9.1e-06 25.9 8.9 3.5 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 KND94835.1 - 1.4e-06 27.7 2.2 0.018 14.3 0.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 KND94835.1 - 0.05 12.5 5.6 0.51 9.2 0.1 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 KND94835.1 - 0.12 11.7 8.1 0.99 8.7 1.9 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DSPc PF00782.20 KND94836.1 - 1.9e-24 86.0 0.0 5.2e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KND94836.1 - 0.0046 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KND94836.1 - 0.091 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain PVL_ORF50 PF07768.11 KND94837.1 - 0.035 14.4 0.7 0.035 14.4 0.7 2.4 2 0 0 2 2 2 0 PVL ORF-50-like family DUF4756 PF15948.5 KND94838.1 - 0.041 13.7 0.6 0.041 13.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) IU_nuc_hydro PF01156.19 KND94839.1 - 6.7e-44 150.7 0.1 1.1e-43 149.9 0.1 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Cyclin_N PF00134.23 KND94841.1 - 2.1e-10 40.4 0.1 4.5e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 KND94842.1 - 3.4e-38 129.0 21.2 3.7e-09 37.1 1.4 7.8 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94842.1 - 4.6e-16 58.9 2.7 0.029 14.7 0.2 5.8 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KND94842.1 - 1.5e-14 53.2 3.9 2.7e-14 52.4 3.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.6 KND94842.1 - 0.0012 18.2 0.1 0.06 12.7 0.0 2.4 2 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KND94842.1 - 0.0021 16.9 0.1 0.032 13.0 0.0 2.1 2 0 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 KND94842.1 - 0.029 13.7 0.0 3.4 6.9 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain Rad60-SLD PF11976.8 KND94844.1 - 9.9e-19 66.9 0.1 2.6e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KND94844.1 - 0.00059 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RhlB PF12300.8 KND94844.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.4 3 1 0 3 3 3 0 ATP-dependent RNA helicase RhlB Zn_clus PF00172.18 KND94846.1 - 1.4e-06 28.3 10.5 2.8e-06 27.3 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.10 KND94846.1 - 6.9e-05 22.5 11.1 0.00026 20.5 11.1 1.8 1 1 0 1 1 1 1 Aflatoxin regulatory protein PCI PF01399.27 KND94847.1 - 2e-10 41.1 0.7 1.4e-09 38.4 0.0 2.8 2 0 0 2 2 2 1 PCI domain GFA PF04828.14 KND94848.1 - 0.0073 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme APH PF01636.23 KND94849.1 - 1e-45 156.5 0.0 2.1e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KND94849.1 - 8.9e-07 28.5 0.3 1.6e-05 24.4 0.1 2.7 2 1 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 KND94849.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KND94849.1 - 0.013 15.1 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KND94849.1 - 0.055 12.8 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SBF_like PF13593.6 KND94850.1 - 1.7e-78 264.1 18.4 2.7e-78 263.4 18.4 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) CBFB_NFYA PF02045.15 KND94851.1 - 2.9e-28 98.2 5.3 7.1e-28 97.0 5.3 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 KND94851.1 - 0.045 12.9 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Erf4 PF10256.9 KND94852.1 - 7.9e-38 129.1 0.0 1.4e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Shadoo PF14999.6 KND94854.1 - 7 6.8 11.0 0.83 9.8 5.0 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF4203 PF13886.6 KND94856.1 - 5.4e-53 179.7 27.9 7.4e-53 179.2 27.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) STE3 PF02076.15 KND94858.1 - 6.4e-69 232.4 16.6 8e-69 232.0 16.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor CAF1C_H4-bd PF12265.8 KND94858.1 - 0.091 13.0 3.4 1.7 9.0 0.9 3.1 3 0 0 3 3 3 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex VRR_NUC PF08774.11 KND94859.1 - 3.6e-21 75.2 0.0 9.5e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Gar1 PF04410.14 KND94860.1 - 4.6e-36 123.9 0.0 6.6e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Dpy-30 PF05186.13 KND94861.1 - 2.8e-15 55.7 0.0 3.9e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif SSB PF00436.25 KND94862.1 - 1.3e-18 67.0 0.0 1.6e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Ribosomal_S13_N PF08069.12 KND94863.1 - 1.2e-28 98.9 0.1 2.2e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KND94863.1 - 3.3e-15 56.1 0.1 5.5e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KND94863.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain YflT PF11181.8 KND94863.1 - 0.12 12.9 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT OGG_N PF07934.12 KND94864.1 - 2.7e-34 117.9 0.0 4.6e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KND94864.1 - 3.7e-16 59.5 0.0 6.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KND94864.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif ABC_membrane PF00664.23 KND94865.1 - 5.5e-101 337.8 37.7 3.7e-51 174.4 14.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND94865.1 - 2e-67 226.0 0.0 1.6e-32 112.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND94865.1 - 1.9e-13 50.4 0.0 4.2e-05 23.1 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KND94865.1 - 3.8e-08 33.4 0.0 0.005 16.8 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 KND94865.1 - 1.9e-07 30.7 0.9 0.0017 18.0 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KND94865.1 - 8.6e-06 26.2 4.5 0.012 16.0 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 KND94865.1 - 5.1e-05 23.1 0.8 0.43 10.2 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KND94865.1 - 0.00015 20.8 5.2 0.037 12.8 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 KND94865.1 - 0.00025 20.7 0.0 0.35 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KND94865.1 - 0.00033 21.1 1.3 6.7 7.1 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KND94865.1 - 0.00091 19.5 2.3 0.45 10.8 0.1 3.4 2 2 0 2 2 2 1 AAA domain G-alpha PF00503.20 KND94865.1 - 0.0038 16.4 0.1 3.7 6.6 0.0 2.8 2 1 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 KND94865.1 - 0.0045 17.2 2.1 4.8 7.5 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KND94865.1 - 0.0073 15.6 0.3 2.9 7.1 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_5 PF07728.14 KND94865.1 - 0.014 15.4 0.2 12 5.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND94865.1 - 0.015 15.4 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 KND94865.1 - 0.016 15.0 5.2 1.1 9.0 0.0 3.5 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KND94865.1 - 0.02 15.0 3.3 4 7.5 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 KND94865.1 - 0.022 15.3 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KND94865.1 - 0.025 14.3 5.8 4 7.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 KND94865.1 - 0.034 14.7 2.0 4.5 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KND94865.1 - 0.038 13.5 0.0 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KND94865.1 - 0.041 13.0 0.2 9.5 5.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KND94865.1 - 0.072 13.0 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PRK PF00485.18 KND94865.1 - 0.099 12.4 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 KND94865.1 - 0.14 11.9 0.1 8.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KND94865.1 - 0.17 12.3 0.2 20 5.6 0.0 3.3 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 KND94865.1 - 0.19 11.8 1.3 11 6.2 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 KND94865.1 - 0.32 11.2 7.4 0.58 10.4 0.1 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 KND94865.1 - 0.42 9.7 3.2 34 3.5 0.0 3.3 2 1 1 3 3 3 0 NB-ARC domain SARAF PF06682.12 KND94866.1 - 5.2e-101 338.6 0.4 6.2e-101 338.4 0.4 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MFS_1 PF07690.16 KND94868.1 - 1.9e-39 135.6 44.8 1.9e-39 135.6 44.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94868.1 - 1.2e-09 37.6 2.2 1.2e-09 37.6 2.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF1996 PF09362.10 KND94869.1 - 2.1e-63 214.5 0.1 2.9e-63 214.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KND94869.1 - 5.1e-18 65.0 8.6 5.1e-18 65.0 8.6 2.1 2 0 0 2 2 2 1 WSC domain Metallophos PF00149.28 KND94870.1 - 1e-07 32.6 0.1 2.7e-07 31.3 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KND94870.1 - 0.0023 18.1 0.0 0.063 13.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2746 PF10874.8 KND94870.1 - 0.0097 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) WYL_3 PF18488.1 KND94870.1 - 0.21 12.0 0.0 1.1 9.7 0.0 2.0 2 0 0 2 2 2 0 WYL domain Velvet PF11754.8 KND94871.1 - 4.3e-51 174.3 0.1 2.5e-32 112.8 0.0 3.3 2 2 1 3 3 3 2 Velvet factor PSI_integrin PF17205.3 KND94873.1 - 1.7 8.5 4.5 0.37 10.6 0.3 2.2 2 0 0 2 2 2 0 Integrin plexin domain RRM_1 PF00076.22 KND94874.1 - 2e-25 88.4 0.2 8.7e-13 47.9 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND94874.1 - 2.8e-06 27.1 0.2 0.011 15.5 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_9 PF18444.1 KND94874.1 - 0.076 12.9 0.1 0.31 10.9 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif Fungal_trans PF04082.18 KND94875.1 - 4.5e-08 32.4 1.9 1.5e-07 30.7 2.4 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3336 PF11815.8 KND94876.1 - 1.4e-33 115.5 0.2 2.6e-32 111.4 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KND94876.1 - 1.1e-13 51.8 0.1 2.8e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3818 PF12825.7 KND94877.1 - 2.3e-130 434.6 6.2 3.4e-130 434.0 6.2 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KND94877.1 - 2.6e-33 114.8 3.7 5.8e-25 87.8 0.2 2.8 3 0 0 3 3 3 2 PX-associated PX PF00787.24 KND94877.1 - 1.3e-14 54.1 0.0 1.5e-13 50.7 0.0 2.7 3 1 0 3 3 3 1 PX domain Cwf_Cwc_15 PF04889.12 KND94877.1 - 0.032 13.9 3.6 0.093 12.5 3.6 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 KND94877.1 - 0.066 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Myc amino-terminal region GFD1 PF17331.2 KND94877.1 - 0.54 10.5 6.2 1.6 9.0 6.2 1.8 1 0 0 1 1 1 0 GFD1 mRNA transport factor FAD_binding_2 PF00890.24 KND94878.1 - 2e-120 402.7 4.9 2.5e-120 402.4 4.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KND94878.1 - 2.5e-42 143.9 1.1 3.9e-42 143.3 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KND94878.1 - 3e-05 23.4 0.8 0.026 13.7 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KND94878.1 - 3.3e-05 23.2 0.2 0.017 14.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 KND94878.1 - 0.0014 17.7 3.1 0.063 12.3 1.6 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KND94878.1 - 0.014 14.7 1.9 0.016 14.5 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.14 KND94878.1 - 0.23 10.1 0.8 0.71 8.5 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein UBA_4 PF14555.6 KND94879.1 - 9.1e-05 22.2 0.1 0.00016 21.4 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain LysM PF01476.20 KND94879.1 - 0.00032 20.7 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 LysM domain Prok-RING_4 PF14447.6 KND94879.1 - 0.091 12.6 9.8 0.19 11.6 9.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PXA PF02194.15 KND94880.1 - 4.2e-43 147.5 0.1 9.9e-43 146.2 0.1 1.7 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.6 KND94880.1 - 2.6e-28 97.9 6.9 5.1e-28 96.9 6.9 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Nexin_C PF08628.12 KND94880.1 - 6.5e-05 23.5 0.0 0.00029 21.4 0.0 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal zf-MYND PF01753.18 KND94880.1 - 0.0031 17.6 0.7 0.0076 16.3 0.7 1.7 1 0 0 1 1 1 1 MYND finger DEAD PF00270.29 KND94881.1 - 1e-11 44.9 0.0 4.4e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94881.1 - 1.8e-05 25.0 0.0 6.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KND94881.1 - 0.015 15.9 0.0 0.048 14.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4332 PF14229.6 KND94881.1 - 0.073 13.3 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4332) Kisspeptin PF15152.6 KND94881.1 - 0.18 12.6 0.4 0.46 11.3 0.4 1.6 1 0 0 1 1 1 0 Kisspeptin ResIII PF04851.15 KND94881.1 - 0.21 11.6 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase PF00069.25 KND94882.1 - 1.8e-32 112.8 0.0 1.9e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND94882.1 - 1.2e-13 50.9 0.0 0.00011 21.6 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KND94882.1 - 0.00024 21.1 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_38N PF01074.22 KND94883.1 - 6.5e-86 288.3 0.2 1e-85 287.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KND94883.1 - 5.6e-49 167.1 0.0 1.1e-48 166.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KND94883.1 - 7.4e-29 99.8 0.0 1.9e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KND94883.1 - 2.7e-11 43.4 0.0 6.7e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Nucleopor_Nup85 PF07575.13 KND94883.1 - 0.053 12.1 0.0 0.082 11.5 0.0 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Glyco_hydro_15 PF00723.21 KND94883.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 DUF1771 PF08590.10 KND94884.1 - 8.4e-16 58.1 10.6 2.1e-15 56.8 10.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KND94884.1 - 2e-08 34.0 8.3 4.6e-06 26.5 0.6 2.8 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KND94884.1 - 3.7e-08 33.6 0.0 1.5e-07 31.7 0.0 2.1 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KND94884.1 - 1e-06 28.5 3.2 0.001 18.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KND94884.1 - 0.00015 21.5 11.8 0.0015 18.3 0.4 3.1 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KND94884.1 - 0.00016 22.0 4.9 0.11 13.0 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 KND94884.1 - 0.003 17.8 0.2 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.16 KND94884.1 - 0.092 12.5 0.0 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 CUE domain Torus PF16131.5 KND94884.1 - 0.25 12.1 5.0 1.5 9.5 0.5 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KND94884.1 - 0.35 11.1 3.5 8.3 6.7 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger containing family SNARE_assoc PF09335.11 KND94885.1 - 5.2e-18 65.7 5.1 5.2e-18 65.7 5.1 2.9 2 1 2 4 4 4 1 SNARE associated Golgi protein FumaraseC_C PF10415.9 KND94885.1 - 0.099 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Fumarase C C-terminus DUF4134 PF13572.6 KND94885.1 - 0.11 12.8 0.1 0.35 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) MutS_V PF00488.21 KND94887.1 - 1.6e-70 237.0 0.0 3.5e-70 235.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND94887.1 - 1.1e-46 159.5 6.0 1.8e-46 158.8 6.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KND94887.1 - 3.3e-20 72.4 0.0 1.3e-19 70.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 KND94887.1 - 9.4e-09 35.7 0.0 3.4e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 KND94887.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KND94887.1 - 0.17 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 KND94889.1 - 6.4e-17 61.9 0.0 9.7e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KND94889.1 - 4e-13 49.8 0.0 6.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KND94889.1 - 2.2e-10 41.2 0.0 3.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND94889.1 - 2e-08 34.8 0.0 3.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND94889.1 - 2.1e-06 27.6 0.0 4.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KND94889.1 - 2.8e-05 23.2 0.0 3.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KND94889.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HSP20 PF00011.21 KND94890.1 - 8.1e-10 38.8 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KND94890.1 - 0.0065 16.0 0.1 0.054 13.0 0.1 2.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA AIM3 PF17096.5 KND94890.1 - 0.28 12.1 6.4 0.57 11.1 3.6 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 LRR_6 PF13516.6 KND94891.1 - 4.9e-09 35.5 7.9 0.028 14.4 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KND94891.1 - 3.9e-07 30.3 13.9 0.0054 17.1 0.0 5.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND94891.1 - 5.3e-05 22.9 9.1 0.041 13.6 0.0 5.1 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 KND94891.1 - 0.03 14.8 5.2 21 6.1 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat LETM1 PF07766.13 KND94891.1 - 0.086 12.2 0.0 0.086 12.2 0.0 2.0 2 1 1 3 3 3 0 LETM1-like protein 3HBOH PF10605.9 KND94891.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Cytochrom_C1 PF02167.15 KND94894.1 - 1e-91 306.6 0.0 1.2e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KND94894.1 - 0.0045 17.3 0.0 0.0092 16.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KND94894.1 - 0.048 14.8 0.0 0.2 12.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c Cpn60_TCP1 PF00118.24 KND94895.1 - 4.6e-133 444.4 22.2 3.6e-131 438.2 22.2 2.1 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family HECT PF00632.25 KND94895.1 - 0.18 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) AAA PF00004.29 KND94896.1 - 3e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND94896.1 - 7.3e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KND94896.1 - 9.8e-05 22.4 0.1 0.00062 19.8 0.0 2.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND94896.1 - 0.00014 22.1 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 KND94896.1 - 0.00019 21.6 0.0 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KND94896.1 - 0.00072 20.0 0.1 0.014 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KND94896.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KND94896.1 - 0.0091 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KND94896.1 - 0.03 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KND94896.1 - 0.034 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KND94896.1 - 0.052 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KND94896.1 - 0.058 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KND94896.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND94896.1 - 0.09 12.5 0.1 0.28 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KND94896.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KND94896.1 - 0.15 11.8 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KND94896.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UCH PF00443.29 KND94899.1 - 2.7e-67 227.0 0.0 3.8e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND94899.1 - 2.2e-12 47.2 0.1 0.0002 21.1 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KND94899.1 - 6.9e-11 42.6 0.0 4.4e-09 36.8 0.0 2.6 2 0 0 2 2 2 1 DUSP domain ubiquitin PF00240.23 KND94899.1 - 0.01 15.6 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family zf-ribbon_3 PF13248.6 KND94899.1 - 0.25 10.8 1.1 3.1 7.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RNA_pol_L_2 PF13656.6 KND94900.1 - 1.7e-30 104.6 0.0 3.8e-30 103.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KND94900.1 - 3.1e-11 42.6 0.0 6e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Spore_coat_CotO PF14153.6 KND94900.1 - 4.8 7.1 16.8 8 6.3 16.8 1.5 1 1 0 1 1 1 0 Spore coat protein CotO Complex1_LYR PF05347.15 KND94901.1 - 3.9e-06 26.8 0.0 7e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KND94901.1 - 5.3e-06 27.1 0.0 6.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.25 KND94903.1 - 1.6e-54 185.0 0.0 3.1e-49 167.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND94903.1 - 1.4e-32 113.0 0.0 3.4e-31 108.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND94903.1 - 5e-08 32.6 0.0 2.6e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KND94903.1 - 0.0004 20.4 0.3 0.001 19.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND94903.1 - 0.0025 16.7 0.0 0.032 13.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_7 PF13499.6 KND94903.1 - 0.12 12.8 0.1 3.1 8.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair HAMP PF00672.25 KND94904.1 - 1.3e-39 134.3 15.7 2.4e-08 34.2 0.0 7.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 KND94904.1 - 4.9e-31 107.5 0.2 2.5e-30 105.3 0.2 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KND94904.1 - 1.6e-26 92.7 0.3 1.7e-25 89.3 0.3 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KND94904.1 - 1.7e-16 60.0 0.6 1.7e-16 60.0 0.6 3.9 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 KND94904.1 - 2.7e-05 24.5 13.3 5.8 7.4 0.0 7.5 2 2 4 6 6 6 2 Syntaxin-like protein Fib_alpha PF08702.10 KND94904.1 - 0.005 17.0 30.6 1.8 8.7 0.7 6.5 6 0 0 6 6 6 2 Fibrinogen alpha/beta chain family DUF948 PF06103.11 KND94904.1 - 0.0093 16.2 45.9 2 8.7 3.2 9.7 2 2 4 6 6 6 3 Bacterial protein of unknown function (DUF948) DUF4279 PF14106.6 KND94904.1 - 0.012 15.8 0.0 35 4.6 0.0 4.3 6 0 0 6 6 4 0 Domain of unknown function (DUF4279) DUF4795 PF16043.5 KND94904.1 - 0.026 14.1 22.4 0.17 11.5 4.7 5.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4795) DUF3829 PF12889.7 KND94904.1 - 0.039 13.4 11.6 1.1 8.6 0.1 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3829) GatB_Yqey PF02637.18 KND94904.1 - 0.11 12.3 3.1 0.31 10.9 0.1 3.3 3 0 0 3 3 3 0 GatB domain GhoS PF11080.8 KND94904.1 - 0.14 12.1 7.8 0.59 10.2 0.1 4.1 4 0 0 4 4 4 0 Endoribonuclease GhoS BORCS6 PF10157.9 KND94904.1 - 1 9.6 12.8 7.6 6.7 0.2 5.7 3 2 1 5 5 5 0 BLOC-1-related complex sub-unit 6 PMC2NT PF08066.12 KND94904.1 - 3.9 8.2 11.7 2.2 9.1 2.4 4.8 5 1 0 5 5 4 0 PMC2NT (NUC016) domain DUF883 PF05957.13 KND94904.1 - 9.5 6.9 20.5 2.7 8.7 0.6 5.9 4 2 3 7 7 7 0 Bacterial protein of unknown function (DUF883) CLZ PF16526.5 KND94905.1 - 0.15 12.4 0.1 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HMG_box PF00505.19 KND94906.1 - 1.8e-16 60.3 1.1 3.1e-16 59.5 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND94906.1 - 5e-14 52.6 1.7 1e-13 51.6 1.7 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KND94906.1 - 2e-10 41.0 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KND94906.1 - 1.4e-07 31.5 0.3 3e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) WW PF00397.26 KND94907.1 - 2.7e-10 40.1 0.1 6.3e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KND94907.1 - 0.003 16.7 0.7 0.19 10.7 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Fungal_trans PF04082.18 KND94909.1 - 9e-15 54.4 0.0 1.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND94909.1 - 1.6e-06 28.1 13.5 2.5e-06 27.5 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.29 KND94910.1 - 8.9e-37 127.0 0.1 2.2e-32 112.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KND94910.1 - 3e-05 23.8 5.2 0.27 10.8 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.26 KND94911.1 - 8.3e-06 26.0 21.4 0.0013 19.0 0.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND94911.1 - 0.0088 16.8 0.4 0.0088 16.8 0.4 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KND94911.1 - 0.34 10.9 3.6 0.24 11.4 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF202 PF02656.15 KND94912.1 - 3e-05 24.4 3.8 3e-05 24.4 3.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3318 PF11780.8 KND94912.1 - 0.02 14.8 1.5 0.028 14.4 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) RseC_MucC PF04246.12 KND94912.1 - 0.19 11.7 1.2 0.34 10.9 0.4 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC AAA_5 PF07728.14 KND94913.1 - 4.4e-116 383.1 0.0 7.7e-22 77.8 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KND94913.1 - 1.3e-54 182.9 8.3 1.5e-21 76.6 0.0 6.1 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KND94913.1 - 3.1e-32 110.8 0.5 4.5e-31 107.1 0.1 3.1 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 KND94913.1 - 9.1e-29 100.0 0.0 1.3e-09 38.0 0.0 5.9 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KND94913.1 - 6.8e-27 94.5 0.0 0.00035 21.0 0.0 7.0 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KND94913.1 - 1.2e-26 93.3 1.7 0.00019 21.0 0.0 7.0 6 1 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 KND94913.1 - 3.3e-26 92.7 18.0 0.00053 20.4 0.0 9.5 7 2 0 7 7 7 6 AAA ATPase domain Dynein_heavy PF03028.15 KND94913.1 - 8.6e-26 90.4 0.0 0.0013 18.8 0.0 8.2 7 0 0 7 7 7 5 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 KND94913.1 - 1.3e-17 64.4 0.2 0.0098 16.2 0.0 7.8 7 0 0 7 7 7 4 AAA domain Sigma54_activat PF00158.26 KND94913.1 - 5.4e-17 62.0 0.0 0.0048 16.6 0.1 5.7 5 0 0 5 5 5 5 Sigma-54 interaction domain AAA_6 PF12774.7 KND94913.1 - 6.3e-17 61.5 0.0 0.0038 16.3 0.0 8.6 9 1 0 9 9 9 3 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 KND94913.1 - 2.3e-14 53.5 1.5 0.0011 18.9 0.2 5.7 5 0 0 5 5 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KND94913.1 - 2.5e-14 53.6 0.1 0.0073 16.5 0.0 6.8 8 0 0 8 8 5 3 AAA domain AAA_18 PF13238.6 KND94913.1 - 3.4e-14 53.5 0.1 0.14 12.8 0.0 7.5 6 0 0 6 6 6 2 AAA domain T2SSE PF00437.20 KND94913.1 - 5.7e-13 48.6 0.0 0.034 13.2 0.0 5.4 5 0 0 5 5 5 3 Type II/IV secretion system protein AAA_14 PF13173.6 KND94913.1 - 6.8e-13 48.8 0.0 0.017 15.2 0.0 6.1 5 0 0 5 5 5 3 AAA domain NACHT PF05729.12 KND94913.1 - 1.3e-11 44.7 3.6 0.073 13.0 0.1 6.1 6 0 0 6 6 5 3 NACHT domain RsgA_GTPase PF03193.16 KND94913.1 - 1.3e-11 44.7 2.9 0.045 13.7 0.2 6.3 6 0 0 6 6 6 2 RsgA GTPase RuvB_N PF05496.12 KND94913.1 - 2.9e-10 40.1 0.8 0.14 11.9 0.0 6.2 6 0 0 6 6 5 2 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KND94913.1 - 5.7e-10 39.9 0.9 0.14 12.7 0.1 6.7 6 1 0 6 6 6 2 ABC transporter RNA_helicase PF00910.22 KND94913.1 - 7e-10 39.3 1.0 0.58 10.6 0.0 6.2 6 0 0 6 6 5 1 RNA helicase IstB_IS21 PF01695.17 KND94913.1 - 1.6e-09 37.7 0.2 0.5 10.1 0.0 6.0 6 0 0 6 6 5 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 KND94913.1 - 6.8e-09 35.3 0.2 0.023 14.0 0.0 5.5 5 0 0 5 5 5 1 Zeta toxin Sigma54_activ_2 PF14532.6 KND94913.1 - 1e-08 35.4 0.4 0.0038 17.3 0.1 5.5 6 0 0 6 6 5 1 Sigma-54 interaction domain AAA_25 PF13481.6 KND94913.1 - 1.1e-07 31.6 1.8 2.3 7.7 0.0 5.8 6 0 0 6 6 5 1 AAA domain Mg_chelatase PF01078.21 KND94913.1 - 6e-07 29.0 1.2 2.6 7.4 0.0 6.6 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 KND94913.1 - 6.4e-07 29.8 2.4 8.2 6.8 0.1 5.7 6 0 0 6 6 4 0 AAA domain NTPase_1 PF03266.15 KND94913.1 - 8.3e-07 29.1 4.4 1.6 8.6 0.0 6.1 7 0 0 7 7 5 1 NTPase Rad17 PF03215.15 KND94913.1 - 9.2e-07 29.0 0.3 0.68 9.8 0.0 5.8 6 0 0 6 6 6 1 Rad17 P-loop domain ATPase_2 PF01637.18 KND94913.1 - 1.3e-06 28.5 0.0 2.4 8.0 0.0 5.8 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KND94913.1 - 3e-06 27.6 3.3 2.8 8.2 0.0 5.9 6 0 0 6 6 5 1 AAA domain TniB PF05621.11 KND94913.1 - 3.7e-06 26.5 0.3 4.2 6.7 0.0 5.4 5 0 0 5 5 5 0 Bacterial TniB protein Roc PF08477.13 KND94913.1 - 1.3e-05 25.4 0.7 6.3 7.1 0.1 5.4 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KND94913.1 - 1.6e-05 24.5 0.0 14 5.5 0.0 5.8 6 0 0 6 6 6 0 P-loop containing region of AAA domain SRP54 PF00448.22 KND94913.1 - 2e-05 24.3 1.5 0.63 9.6 0.1 4.9 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KND94913.1 - 2e-05 24.4 0.1 0.4 10.4 0.0 5.4 5 0 0 5 5 5 1 AAA domain DUF815 PF05673.13 KND94913.1 - 2.6e-05 23.5 0.4 2.8 7.0 0.0 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 KND94913.1 - 4.8e-05 23.3 0.8 16 5.3 0.0 5.6 6 0 0 6 6 6 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 KND94913.1 - 5.6e-05 23.2 0.1 23 5.1 0.0 5.7 5 0 0 5 5 5 0 50S ribosome-binding GTPase TIP49 PF06068.13 KND94913.1 - 8.2e-05 22.0 0.9 1.3 8.2 0.0 4.0 5 0 0 5 5 4 1 TIP49 P-loop domain PduV-EutP PF10662.9 KND94913.1 - 0.00016 21.4 1.2 2.4 7.9 0.1 4.5 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KND94913.1 - 0.00017 20.9 0.6 1.7 7.8 0.0 4.3 4 0 0 4 4 4 1 NB-ARC domain dNK PF01712.19 KND94913.1 - 0.00043 20.2 0.6 27 4.5 0.0 4.5 4 0 0 4 4 4 0 Deoxynucleoside kinase GAF_2 PF13185.6 KND94913.1 - 0.0012 19.1 0.4 0.5 10.7 0.0 4.2 5 0 0 5 5 3 1 GAF domain Viral_helicase1 PF01443.18 KND94913.1 - 0.0021 17.9 0.1 5.6 6.6 0.0 4.5 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase AAA_9 PF12781.7 KND94913.1 - 0.0078 15.4 0.0 0.43 9.7 0.0 3.7 3 0 0 3 3 3 1 ATP-binding dynein motor region DEAD PF00270.29 KND94913.1 - 0.0082 15.9 0.1 3.6 7.3 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase DnaB_C PF03796.15 KND94913.1 - 0.011 15.1 1.0 0.46 9.8 0.0 3.5 4 0 0 4 4 2 0 DnaB-like helicase C terminal domain CbiA PF01656.23 KND94913.1 - 0.013 15.5 0.0 53 3.9 0.0 4.3 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 KND94913.1 - 0.047 12.7 1.0 2.6 7.0 0.1 3.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 KND94913.1 - 0.07 12.5 0.0 45 3.3 0.0 4.0 4 0 0 4 4 4 0 KaiC FtsK_SpoIIIE PF01580.18 KND94913.1 - 0.073 12.4 0.1 9.5 5.5 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 KND94913.1 - 0.078 12.6 5.5 23 4.5 0.1 4.7 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 KND94913.1 - 0.11 12.5 9.6 2.3 8.2 0.1 5.3 6 0 0 6 6 5 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KND94913.1 - 0.12 11.8 0.2 14 5.0 0.0 3.8 4 0 0 4 4 4 0 PhoH-like protein IPT PF01745.16 KND94913.1 - 0.14 11.5 0.0 6.3 6.1 0.0 2.7 2 0 0 2 2 2 0 Isopentenyl transferase ATP_bind_1 PF03029.17 KND94913.1 - 1.8 8.3 5.9 30 4.3 0.0 4.1 6 0 0 6 6 4 0 Conserved hypothetical ATP binding protein Hpr_kinase_C PF07475.12 KND94913.1 - 2.1 7.9 3.7 2.4 7.7 0.1 2.9 4 0 0 4 4 2 0 HPr Serine kinase C-terminal domain Isochorismatase PF00857.20 KND94914.1 - 9.7e-17 61.7 0.1 1.9e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 KND94916.1 - 8.4e-18 65.4 0.0 1.3e-17 64.7 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KND94916.1 - 4.7e-15 56.1 0.0 6.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF2938 PF11158.8 KND94916.1 - 0.0057 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) BP28CT PF08146.12 KND94917.1 - 7.3e-43 146.1 0.3 1.1e-41 142.3 0.1 2.8 2 1 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KND94917.1 - 2.6e-22 79.4 7.9 8.9e-22 77.6 0.2 5.5 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KND94917.1 - 1.3e-06 28.1 10.6 0.0072 16.5 0.1 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 KND94917.1 - 0.0038 17.6 17.0 0.92 9.9 1.1 6.5 6 1 1 7 7 7 2 HEAT repeats RTP1_C1 PF10363.9 KND94917.1 - 0.046 13.9 0.3 0.77 10.0 0.1 3.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 KND94917.1 - 0.12 12.9 14.0 0.14 12.7 0.4 6.1 5 1 1 6 6 6 0 HEAT-like repeat TMP-TENI PF02581.17 KND94918.1 - 4.7e-42 143.4 0.3 7.7e-42 142.7 0.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase HK PF02110.15 KND94918.1 - 1.3e-36 126.3 6.7 1.8e-36 125.8 6.7 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KND94918.1 - 0.00017 21.2 0.8 0.00017 21.2 0.8 2.0 2 1 0 3 3 3 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KND94918.1 - 0.013 14.9 1.3 0.019 14.4 1.3 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Zn_clus PF00172.18 KND94919.1 - 5.1 7.3 13.1 9.3 6.5 13.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 KND94920.1 - 5.6e-78 262.6 0.0 7.1e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KND94920.1 - 0.00028 19.5 0.0 0.00046 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KND94920.1 - 0.0021 17.4 0.3 0.0037 16.6 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KND94920.1 - 0.0025 16.9 0.0 0.0047 15.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V CTK3 PF12243.8 KND94921.1 - 5.6e-45 152.3 0.1 9.2e-45 151.6 0.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KND94921.1 - 1.3e-19 70.1 12.3 1.3e-19 70.1 12.3 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Ribosomal_L12 PF00542.19 KND94922.1 - 6.8e-21 74.4 8.0 5.8e-20 71.4 5.5 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KND94922.1 - 4.6e-13 48.6 11.9 4.8e-13 48.6 8.6 2.7 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KND94922.1 - 0.021 14.6 0.9 0.079 12.7 0.3 2.2 2 1 0 2 2 2 0 Stage VI sporulation protein F BCNT PF07572.12 KND94923.1 - 6e-23 80.7 1.0 6e-23 80.7 1.0 1.7 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF4602 PF15375.6 KND94924.1 - 6.1e-08 33.1 17.2 1.2e-06 28.8 17.2 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) SspP PF08179.12 KND94924.1 - 0.98 9.9 4.2 14 6.3 0.2 3.0 3 0 0 3 3 3 0 Small acid-soluble spore protein P family SNF2_N PF00176.23 KND94925.1 - 2.7e-71 240.1 0.9 2.7e-71 240.1 0.9 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND94925.1 - 8.5e-21 74.4 0.3 5.6e-18 65.3 0.0 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KND94925.1 - 4.3e-19 68.4 0.1 1e-18 67.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 KND94925.1 - 7e-18 64.7 15.4 7e-18 64.7 15.4 5.7 8 0 0 8 8 8 1 HSA SnAC PF14619.6 KND94925.1 - 3.3e-15 56.5 1.4 3.3e-15 56.5 1.4 4.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KND94925.1 - 6.7e-11 42.5 1.4 3.6e-10 40.1 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.11 KND94925.1 - 1.7e-10 40.5 6.4 1.7e-10 40.5 6.4 2.2 2 0 0 2 2 2 1 QLQ RBR PF17208.3 KND94925.1 - 0.00034 21.3 5.8 0.00034 21.3 5.8 3.3 2 1 1 3 3 3 1 RNA binding Region WD40 PF00400.32 KND94926.1 - 6.3e-07 30.0 11.7 0.022 15.6 0.5 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat PTPLA PF04387.14 KND94927.1 - 5.8e-44 149.7 6.2 9.2e-44 149.1 6.2 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DIOX_N PF14226.6 KND94927.1 - 7.8e-20 71.8 0.0 2.1e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KND94927.1 - 3.2e-17 62.9 0.0 7.7e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APH PF01636.23 KND94927.1 - 8.3e-09 35.7 1.9 8.3e-09 35.7 1.9 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family PGAP1 PF07819.13 KND94928.1 - 0.00063 19.5 0.0 0.00097 18.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KND94928.1 - 0.0021 18.7 5.4 0.0066 17.1 5.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KND94928.1 - 0.0065 16.0 0.0 0.0096 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 KND94928.1 - 0.0095 15.2 0.3 0.042 13.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KND94928.1 - 0.04 12.8 0.0 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme DnaJ PF00226.31 KND94929.1 - 4.3e-14 52.4 0.1 4.3e-14 52.4 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain CDC45 PF02724.14 KND94929.1 - 4.9 5.3 16.7 5.2 5.2 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_2 PF04909.14 KND94930.1 - 3.1e-30 105.9 0.0 3.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KND94930.1 - 0.0014 18.0 0.0 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 TatD related DNase GCV_T PF01571.21 KND94931.1 - 3.7e-08 33.0 0.0 5.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Sds3 PF08598.11 KND94932.1 - 6.8e-15 55.7 1.4 6.8e-15 55.7 1.4 2.1 2 1 0 2 2 2 1 Sds3-like Hpt PF01627.23 KND94932.1 - 0.0085 16.3 0.2 0.03 14.6 0.2 2.0 1 0 0 1 1 1 1 Hpt domain LAM_C PF12544.8 KND94932.1 - 0.77 9.9 5.1 1.2 9.3 0.5 2.6 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Peptidase_M20 PF01546.28 KND94933.1 - 7.9e-07 29.0 0.0 1.3e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KND94933.1 - 0.00078 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CoA_binding PF02629.19 KND94934.1 - 2.2e-20 73.1 0.4 5.8e-20 71.8 0.4 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 KND94934.1 - 8.2e-15 54.9 0.8 1.4e-14 54.1 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KND94934.1 - 3e-11 43.3 0.5 6.9e-11 42.1 0.5 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain DUF1624 PF07786.12 KND94934.1 - 8.3 5.9 18.9 4.7 6.7 11.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1624) DEAD PF00270.29 KND94936.1 - 1.7e-51 174.5 0.0 4e-51 173.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND94936.1 - 1.7e-33 115.3 0.0 8.7e-30 103.3 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain UTP25 PF06862.12 KND94936.1 - 0.011 14.6 0.0 0.04 12.7 0.0 2.0 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SRP1_TIP1 PF00660.17 KND94936.1 - 0.052 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family Abhydrolase_2 PF02230.16 KND94937.1 - 3.4e-17 63.0 0.0 1.5e-10 41.3 0.0 2.0 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KND94937.1 - 0.0015 18.1 0.0 0.014 14.9 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KND94937.1 - 0.0057 15.9 0.0 0.94 8.7 0.0 2.3 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND94937.1 - 0.033 14.8 3.8 0.079 13.6 3.6 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family AMP-binding PF00501.28 KND94938.1 - 1.2e-71 241.5 0.0 1.9e-71 240.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KND94938.1 - 4.3e-62 209.6 0.0 6.4e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KND94938.1 - 1.2e-10 41.2 0.0 2.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KND94938.1 - 6.6e-09 36.0 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 KND94938.1 - 8.4e-06 25.8 0.2 4.1e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KND94938.1 - 9.2e-06 24.9 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 KND94938.1 - 0.0005 21.0 0.0 0.0021 19.0 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rnk_N PF14760.6 KND94938.1 - 0.027 14.9 0.2 2.7 8.5 0.1 3.3 3 0 0 3 3 3 0 Rnk N-terminus GDP_Man_Dehyd PF16363.5 KND94938.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Rft-1 PF04506.13 KND94939.1 - 2.6e-149 498.3 2.7 2.9e-149 498.1 2.7 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KND94939.1 - 0.00016 21.2 11.7 0.00016 21.2 11.7 3.2 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KND94940.1 - 5.6e-25 88.0 48.9 3.6e-17 62.3 31.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Iwr1 PF08574.10 KND94942.1 - 4.1e-15 56.6 8.9 4.1e-15 56.6 8.9 3.3 3 1 0 3 3 3 2 Transcription factor Iwr1 GPI-anchored PF10342.9 KND94943.1 - 5.6e-21 75.1 0.1 5.6e-21 75.1 0.1 2.7 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.16 KND94944.1 - 7.4e-27 94.2 20.5 7.4e-27 94.2 20.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 KND94946.1 - 3.1e-56 186.1 13.5 2.7e-09 37.5 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND94946.1 - 5.6e-21 74.6 0.0 0.00028 21.1 0.0 6.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND94946.1 - 2.7e-07 29.7 2.8 0.035 12.8 0.1 4.7 2 2 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KND94946.1 - 1.3e-06 28.5 0.0 0.00036 20.5 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KND94946.1 - 4.5e-05 22.6 0.1 8.3 5.3 0.0 4.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KND94946.1 - 4.8e-05 22.6 1.1 5.7 5.9 0.0 4.0 1 1 1 4 4 4 3 Protein of unknown function (DUF1513) VID27 PF08553.10 KND94946.1 - 0.0013 17.9 0.0 1.4 7.9 0.0 3.8 2 1 2 5 5 5 2 VID27 C-terminal WD40-like domain WD40_like PF17005.5 KND94946.1 - 0.0071 15.7 0.0 0.22 10.8 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 KND94946.1 - 0.04 14.0 0.0 6.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 KND94946.1 - 0.087 11.1 0.0 0.82 7.9 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 KND94947.1 - 5.3e-67 226.0 0.0 8.9e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94947.1 - 2e-36 125.6 0.0 3.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND94947.1 - 0.00052 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KND94947.1 - 0.0042 17.0 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KND94947.1 - 0.0046 15.8 0.0 0.0096 14.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase NOG1_N PF17835.1 KND94947.1 - 0.082 12.9 3.7 0.24 11.4 0.1 3.3 3 0 0 3 3 3 0 NOG1 N-terminal helical domain ATPase PF06745.13 KND94947.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 KaiC His_Phos_2 PF00328.22 KND94948.1 - 0.0079 15.6 0.0 0.42 9.9 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.16 KND94949.1 - 1.6e-29 103.0 31.5 1.6e-29 103.0 31.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94949.1 - 2.9e-08 33.0 11.0 2.9e-08 33.0 11.0 3.0 3 1 1 4 4 4 1 Sugar (and other) transporter PTR2 PF00854.21 KND94949.1 - 4.1e-05 22.6 2.3 4.1e-05 22.6 2.3 1.9 3 0 0 3 3 3 1 POT family Prenyltrans PF00432.21 KND94950.1 - 6.9e-55 182.5 7.8 1.4e-11 43.9 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KND94950.1 - 0.0004 19.6 0.0 0.16 11.0 0.0 3.1 3 1 1 4 4 4 2 Squalene-hopene cyclase N-terminal domain Glyco_hydro_76 PF03663.14 KND94952.1 - 7.7e-146 486.3 3.4 8.9e-146 486.1 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KND94952.1 - 0.41 9.7 8.1 3.8 6.5 0.4 2.5 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Zn_clus PF00172.18 KND94954.1 - 3.2e-06 27.2 15.3 5.3e-06 26.5 15.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KND94954.1 - 6.1e-05 22.0 0.1 0.0001 21.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_1 PF00583.25 KND94955.1 - 6.3e-07 29.6 0.1 1.3e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KND94955.1 - 1.7e-06 28.0 0.0 3.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KND94955.1 - 2.6e-05 24.6 0.0 5.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RGS PF00615.19 KND94955.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain CinA PF02464.17 KND94956.1 - 1.3e-44 151.5 0.3 1.6e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Competence-damaged protein PARP PF00644.20 KND94957.1 - 1.2e-06 28.2 0.2 1.2e-05 25.0 0.0 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain FYRN PF05964.14 KND94957.1 - 0.032 14.1 0.3 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 F/Y-rich N-terminus MFS_1 PF07690.16 KND94958.1 - 3.1e-08 32.9 0.2 3.9e-08 32.6 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DivIVA PF05103.13 KND94960.1 - 0.0003 20.9 22.0 0.13 12.4 7.6 3.4 2 1 1 3 3 3 2 DivIVA protein HAP1_N PF04849.13 KND94960.1 - 0.015 14.5 0.9 0.015 14.5 0.9 3.5 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF1940 PF09155.10 KND94960.1 - 0.038 14.1 0.8 0.091 12.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) LemA PF04011.12 KND94960.1 - 0.24 11.2 5.3 0.5 10.2 4.1 2.1 1 1 1 2 2 2 0 LemA family Tropomyosin PF00261.20 KND94960.1 - 0.97 8.7 30.3 3.5 6.9 15.7 3.3 1 1 2 3 3 3 0 Tropomyosin KASH_CCD PF14662.6 KND94960.1 - 1.9 8.3 24.7 0.89 9.3 0.0 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 KND94960.1 - 1.9 8.7 17.9 0.17 12.1 0.8 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.13 KND94960.1 - 4.1 5.6 28.3 0.2 10.0 11.3 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 KND94960.1 - 6.2 7.2 23.4 3.2 8.2 20.6 1.9 1 1 1 2 2 2 0 Fez1 Pyr_redox_2 PF07992.14 KND94961.1 - 4.1e-49 167.4 2.6 5.9e-49 166.9 2.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KND94961.1 - 2.9e-14 53.4 2.4 1.5e-11 44.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KND94961.1 - 3.4e-14 52.6 0.0 7.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 KND94961.1 - 1.1e-06 29.1 0.0 4.6e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 Reductase C-terminal Pyr_redox_3 PF13738.6 KND94961.1 - 4.1e-06 26.3 0.0 0.0015 17.8 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KND94961.1 - 0.0001 21.5 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 KND94961.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 KND94961.1 - 0.023 15.1 1.4 0.82 10.1 0.1 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 KND94961.1 - 0.074 13.0 2.5 13 5.7 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KND94961.1 - 0.12 12.7 3.8 0.56 10.5 0.1 2.8 2 0 0 2 2 2 0 TrkA-N domain Cnd2 PF05786.14 KND94962.1 - 0 1049.0 5.1 0 1048.8 5.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KND94962.1 - 0.0052 17.0 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Merozoite_SPAM PF07133.11 KND94962.1 - 0.086 12.8 9.1 0.14 12.2 2.2 2.4 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) tRNA-synt_1b PF00579.25 KND94963.1 - 9.4e-21 74.4 0.3 6.4e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Peptidase_S10 PF00450.22 KND94964.1 - 1.1e-121 407.2 1.0 1.3e-121 406.9 1.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KND94964.1 - 1.6e-21 77.2 0.2 4e-21 75.8 0.2 1.7 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide ELO PF01151.18 KND94965.1 - 1.2e-79 267.3 8.4 1.5e-79 267.0 8.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4141 PF13605.6 KND94965.1 - 0.076 12.3 0.1 0.21 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) MoaC PF01967.21 KND94966.1 - 2.3e-52 176.7 3.5 3.6e-52 176.1 3.5 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KND94966.1 - 4.7e-38 130.0 0.0 1.9e-36 124.8 0.0 2.5 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KND94966.1 - 7.2e-24 85.0 0.0 1.3e-23 84.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily FYVE PF01363.21 KND94966.1 - 3e-14 52.9 7.0 8.2e-14 51.5 7.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger Fer4_12 PF13353.6 KND94966.1 - 3.3e-05 24.2 0.1 0.00011 22.5 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain zf-AN1 PF01428.16 KND94966.1 - 0.98 9.6 7.6 3.5 7.9 7.6 2.0 1 0 0 1 1 1 0 AN1-like Zinc finger tRNA_int_end_N2 PF12928.7 KND94967.1 - 0.078 13.2 0.0 0.44 10.8 0.0 2.3 3 0 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_end_N2 PF12928.7 KND94968.1 - 0.078 13.2 0.0 0.44 10.8 0.0 2.3 3 0 0 3 3 3 0 tRNA-splicing endonuclease subunit sen54 N-term MCM PF00493.23 KND94969.1 - 9.2e-104 345.4 0.0 2.1e-103 344.2 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KND94969.1 - 4.8e-30 104.0 1.7 5.6e-30 103.8 0.6 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KND94969.1 - 1.5e-20 73.4 1.0 3.4e-20 72.2 1.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KND94969.1 - 5.4e-18 65.5 3.8 6.6e-18 65.2 0.6 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 KND94969.1 - 6.4e-08 32.2 0.0 8.4e-06 25.3 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KND94969.1 - 2.5e-06 27.5 0.0 8.8e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 KND94969.1 - 0.0014 18.4 0.1 0.0046 16.8 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 KND94969.1 - 0.0076 16.9 2.7 0.01 16.4 0.2 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KND94969.1 - 0.016 15.1 0.0 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KND94969.1 - 0.032 13.9 0.2 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 KND94969.1 - 0.097 12.4 0.2 0.62 9.7 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain Herpes_UL42 PF02282.16 KND94970.1 - 0.013 15.4 0.1 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase processivity factor (UL42) Prok-E2_A PF14457.6 KND94970.1 - 0.19 11.3 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A HEAT_2 PF13646.6 KND94971.1 - 6.7e-13 48.8 5.3 0.05 14.0 0.0 7.4 8 0 0 8 8 7 4 HEAT repeats HEAT PF02985.22 KND94971.1 - 1.1e-07 31.4 20.7 0.36 11.2 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat Vac14_Fab1_bd PF12755.7 KND94971.1 - 1.7e-07 31.8 0.9 0.038 14.6 0.0 5.2 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KND94971.1 - 0.00015 21.4 0.4 5.1 6.6 0.0 4.7 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 KND94971.1 - 0.0012 19.3 15.1 0.34 11.5 0.0 6.6 5 1 2 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 KND94971.1 - 0.0013 18.8 0.2 3.1 7.8 0.0 5.2 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KND94971.1 - 0.017 13.7 4.1 25 3.3 0.0 5.7 4 2 0 6 6 6 0 Adaptin N terminal region UNC45-central PF11701.8 KND94971.1 - 0.023 14.6 0.1 1.5 8.7 0.0 3.6 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central V-ATPase_H_C PF11698.8 KND94971.1 - 0.039 14.1 0.1 13 6.0 0.0 3.9 3 0 0 3 3 3 0 V-ATPase subunit H IFRD PF05004.13 KND94971.1 - 0.14 11.2 9.5 0.03 13.5 1.2 3.9 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 KND94971.1 - 0.16 12.3 0.3 9.4 6.6 0.1 4.1 4 0 0 4 4 3 0 TAF6 C-terminal HEAT repeat domain Transcrip_reg PF01709.20 KND94972.1 - 3.8e-61 206.6 0.0 4.4e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator RXLR_WY PF18634.1 KND94972.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain PH_9 PF15410.6 KND94973.1 - 9.5e-09 35.7 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KND94973.1 - 0.003 18.0 0.1 0.0055 17.2 0.1 1.5 1 0 0 1 1 1 1 PH domain EXS PF03124.14 KND94973.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 EXS family MutS_V PF00488.21 KND94974.1 - 3.4e-73 245.7 0.1 8.8e-73 244.4 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KND94974.1 - 2.1e-35 122.7 1.9 2.1e-35 122.7 1.9 1.9 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KND94974.1 - 6.7e-29 100.4 0.0 1.9e-28 98.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KND94974.1 - 7.9e-12 45.6 0.7 8.3e-10 39.1 0.0 3.2 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 KND94974.1 - 0.00019 21.7 0.0 0.00062 20.1 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 KND94974.1 - 0.0062 16.5 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4911) MMS19_N PF14500.6 KND94974.1 - 0.027 14.1 0.7 1.5 8.3 0.3 2.4 1 1 1 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II AAA_29 PF13555.6 KND94974.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_E PF05680.12 KND94975.1 - 1.2e-23 83.3 0.0 1.7e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase E chain WD40 PF00400.32 KND94976.1 - 5e-09 36.6 7.1 0.32 11.9 0.8 6.5 6 1 0 6 6 6 3 WD domain, G-beta repeat MerR-DNA-bind PF09278.11 KND94976.1 - 5.4 7.6 7.8 1.1 9.8 2.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding Fcf1 PF04900.12 KND94977.1 - 5.1e-30 103.8 0.2 9.4e-30 102.9 0.2 1.4 1 0 0 1 1 1 1 Fcf1 DNA_pol_phi PF04931.13 KND94977.1 - 0.056 11.6 0.6 0.07 11.2 0.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma_reg_N PF13800.6 KND94977.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CDC45 PF02724.14 KND94977.1 - 2.4 6.3 4.7 3.6 5.8 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PP2C_2 PF13672.6 KND94978.1 - 0.00053 19.7 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KND94978.1 - 0.00065 19.7 0.1 0.0023 17.9 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) VSP PF03302.13 KND94979.1 - 0.00018 20.5 2.1 0.00025 20.0 2.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.6 KND94979.1 - 0.17 12.7 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KND94979.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Podoplanin PF05808.11 KND94979.1 - 0.23 11.5 3.7 0.095 12.8 0.5 2.0 2 0 0 2 2 2 0 Podoplanin DUF726 PF05277.12 KND94980.1 - 7.8e-127 422.9 2.2 1.1e-126 422.4 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) STT3 PF02516.14 KND94981.1 - 5.4e-127 424.7 33.7 1e-82 278.6 22.1 3.1 2 1 1 3 3 3 3 Oligosaccharyl transferase STT3 subunit PH PF00169.29 KND94982.1 - 1.6e-07 31.8 0.0 8.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KND94982.1 - 0.0021 18.4 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.25 KND94984.1 - 1.6e-61 208.0 0.0 5.8e-61 206.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94984.1 - 3.2e-28 98.7 0.0 5.8e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KND94984.1 - 1.9e-10 40.9 0.1 5.2e-10 39.5 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KND94984.1 - 0.0014 18.9 0.0 0.0066 16.7 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KND94984.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE PF01363.21 KND94986.1 - 4.4e-21 74.8 0.4 4.4e-21 74.8 0.4 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KND94986.1 - 3.2e-07 30.6 5.0 3.2e-07 30.6 5.0 3.9 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 KND94986.1 - 0.00032 20.4 4.2 0.00032 20.4 4.2 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KND94986.1 - 0.00052 19.8 4.1 0.00052 19.8 4.1 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND94986.1 - 0.0023 17.9 5.7 0.0023 17.9 5.7 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING-like PF08746.11 KND94986.1 - 0.0044 17.3 2.4 0.0044 17.3 2.4 2.7 2 0 0 2 2 1 1 RING-like domain FYVE_2 PF02318.16 KND94986.1 - 0.016 15.4 8.8 0.022 15.0 1.9 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger Rad50_zn_hook PF04423.14 KND94986.1 - 0.05 13.4 2.5 0.16 11.8 0.6 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 KND94986.1 - 0.25 11.4 8.7 2 8.5 4.8 2.8 2 0 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 KND94986.1 - 0.32 11.2 16.3 0.089 12.9 5.7 3.2 4 0 0 4 4 4 0 Piccolo Zn-finger Zn-C2H2_12 PF18112.1 KND94986.1 - 0.43 11.1 7.4 6.4 7.3 0.2 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Elf1 PF05129.13 KND94986.1 - 5.4 7.1 13.2 4 7.5 4.0 3.6 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like C2 PF00168.30 KND94987.1 - 9.6e-85 279.6 0.4 3.4e-22 78.7 0.0 5.3 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KND94987.1 - 0.0038 16.7 0.0 0.008 15.7 0.0 1.5 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain ABC_membrane PF00664.23 KND94989.1 - 1.5e-72 244.6 35.3 1.4e-43 149.5 8.5 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KND94989.1 - 2.2e-61 206.4 0.0 1.9e-32 112.6 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KND94989.1 - 3e-11 43.2 5.6 0.0013 18.2 2.6 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KND94989.1 - 6.6e-07 29.4 0.1 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KND94989.1 - 1.1e-06 28.3 0.7 0.0012 18.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KND94989.1 - 1.2e-06 28.5 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KND94989.1 - 1.5e-06 28.5 2.0 0.061 13.6 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KND94989.1 - 2.1e-06 28.2 1.4 0.085 13.2 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 KND94989.1 - 2.6e-06 27.5 0.0 0.68 9.7 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KND94989.1 - 2.2e-05 24.3 2.8 0.27 10.9 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 KND94989.1 - 0.00015 22.3 0.0 0.014 15.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KND94989.1 - 0.0011 18.6 0.1 1.6 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KND94989.1 - 0.0028 16.5 0.3 0.5 9.1 0.0 3.3 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 KND94989.1 - 0.0029 17.6 0.0 3.7 7.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 KND94989.1 - 0.0054 16.3 0.0 4.4 6.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATP-synt_ab PF00006.25 KND94989.1 - 0.0088 15.7 0.0 3.6 7.2 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 KND94989.1 - 0.009 15.1 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) PRK PF00485.18 KND94989.1 - 0.016 15.0 0.0 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 KND94989.1 - 0.022 14.7 0.1 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 KND94989.1 - 0.031 14.0 0.7 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KND94989.1 - 0.032 14.7 2.7 24 5.4 0.2 4.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KND94989.1 - 0.041 14.0 0.4 2.8 8.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KND94989.1 - 0.052 12.7 0.3 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.6 KND94989.1 - 0.054 13.7 0.7 2.4 8.4 0.7 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KND94989.1 - 0.075 13.1 0.2 5 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KND94989.1 - 0.1 13.1 0.1 10 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KND94989.1 - 0.14 12.4 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.26 KND94990.1 - 7.7e-26 90.4 0.0 1e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND94990.1 - 3.6e-08 33.2 0.0 1.7e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KND94990.1 - 0.00013 21.9 0.1 0.00025 20.9 0.1 1.5 2 0 0 2 2 2 1 UEV domain RWD PF05773.22 KND94990.1 - 0.003 17.8 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 KND94990.1 - 0.045 13.4 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 KND94991.1 - 4.2e-65 219.7 0.0 6.2e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND94991.1 - 4e-33 114.8 0.1 4.2e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KND94991.1 - 1.9e-06 27.4 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KND94991.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KND94991.1 - 0.23 10.9 0.0 0.23 10.9 0.0 2.1 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Ribosomal_L41 PF05162.13 KND94991.1 - 0.98 9.5 3.5 2.1 8.5 3.5 1.6 1 0 0 1 1 1 0 Ribosomal protein L41 MFS_1 PF07690.16 KND94992.1 - 2.6e-36 125.3 22.7 2.6e-36 125.3 22.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND94992.1 - 4e-13 49.0 9.5 4e-13 49.0 9.5 2.8 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KND94992.1 - 0.0096 14.4 3.1 0.018 13.5 3.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrolase_4 PF12146.8 KND94994.1 - 5.7e-11 42.1 0.1 9.9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KND94994.1 - 5.7e-09 36.9 10.4 5.7e-09 36.9 10.4 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND94994.1 - 5.1e-08 32.9 0.3 9.8e-08 31.9 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 KND94994.1 - 0.0093 15.9 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Fungal_trans PF04082.18 KND94995.1 - 2.2e-15 56.4 0.5 5.7e-15 55.1 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KND94995.1 - 1.2e-12 47.5 8.0 4.6e-06 26.8 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND94995.1 - 5.4e-06 26.8 7.1 0.00044 20.9 0.3 3.4 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_clus PF00172.18 KND94995.1 - 8.4e-06 25.8 10.1 2.5e-05 24.3 10.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KND94995.1 - 0.00042 20.6 6.9 0.02 15.3 0.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 KND94995.1 - 0.021 15.2 2.1 0.12 12.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KND94995.1 - 0.043 14.1 2.8 0.45 10.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Amidohydro_3 PF07969.11 KND94996.1 - 2.1e-15 57.2 2.7 1.3e-08 34.8 0.0 2.7 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KND94996.1 - 2.2e-12 47.0 0.0 7.2e-09 35.4 0.0 3.3 3 0 0 3 3 3 2 Amidohydrolase family Melibiase_2 PF16499.5 KND94997.1 - 8.4e-49 166.2 0.2 2.1e-48 164.9 0.2 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KND94997.1 - 1.7e-12 47.2 1.5 6.1e-12 45.4 0.2 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 KND94997.1 - 8.5e-10 39.0 1.1 1.5e-09 38.1 1.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KND94997.1 - 0.0029 18.3 2.0 0.27 12.0 0.0 3.3 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Melibiase PF02065.18 KND94997.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Melibiase CDtoxinA PF03498.14 KND94997.1 - 0.041 13.5 0.4 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Allantoicase PF03561.15 KND94997.1 - 0.14 12.1 0.0 5 7.1 0.0 2.9 2 1 0 2 2 2 0 Allantoicase repeat Dus PF01207.17 KND94998.1 - 3.3e-48 164.4 0.2 2.5e-47 161.5 0.2 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 KND94998.1 - 0.0072 15.7 0.1 0.1 11.9 0.0 2.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KND94998.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ApoO PF09769.9 KND94999.1 - 1.6e-42 144.6 1.0 3.8e-42 143.3 0.0 2.0 3 0 0 3 3 3 1 Apolipoprotein O Nop14 PF04147.12 KND95000.1 - 1.2e-299 996.6 21.0 1.4e-299 996.3 21.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.6 KND95001.1 - 6.5e-22 77.1 2.0 1.9e-21 75.6 2.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KND95001.1 - 2.1e-09 37.1 4.7 5e-09 35.9 4.7 1.7 1 0 0 1 1 1 1 G-patch domain SecD-TM1 PF13721.6 KND95001.1 - 0.0033 17.9 0.1 0.0087 16.5 0.1 1.7 1 0 0 1 1 1 1 SecD export protein N-terminal TM region FAM183 PF14886.6 KND95001.1 - 0.079 13.7 0.4 0.079 13.7 0.4 1.8 2 0 0 2 2 2 0 FAM183A and FAM183B related BTV_NS2 PF04514.12 KND95001.1 - 0.45 9.3 5.8 0.82 8.4 5.8 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rimk_N PF18030.1 KND95001.1 - 0.83 10.1 2.3 4.6 7.7 0.2 2.3 2 0 0 2 2 2 0 RimK PreATP-grasp domain DUF2868 PF11067.8 KND95001.1 - 2.8 7.4 4.3 0.95 8.9 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) HSP70 PF00012.20 KND95002.1 - 4.5e-05 21.8 0.0 7.2e-05 21.2 0.0 1.3 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 KND95002.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HlyIII PF03006.20 KND95003.1 - 4.4e-51 173.8 11.8 5.2e-51 173.5 11.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related CPSF_A PF03178.15 KND95004.1 - 0.0076 15.6 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region WD40 PF00400.32 KND95004.1 - 0.037 14.9 0.1 29 5.7 0.1 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat CDC45 PF02724.14 KND95004.1 - 0.51 8.6 3.9 0.69 8.1 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ_C PF01556.18 KND95005.1 - 6.9e-37 126.8 0.2 9.1e-37 126.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KND95005.1 - 5.3e-22 77.7 4.1 8.7e-22 77.0 4.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KND95005.1 - 7.3e-17 61.5 17.6 1.3e-16 60.7 17.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KND95005.1 - 0.0027 17.6 17.7 0.11 12.5 3.0 2.7 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KND95005.1 - 0.074 13.1 9.5 0.74 9.9 2.6 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2614 PF11023.8 KND95005.1 - 0.79 9.8 6.6 1.6 8.9 1.2 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain zinc-ribbons_6 PF07191.12 KND95005.1 - 0.84 9.7 8.2 4.6 7.3 2.2 2.4 1 1 1 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.6 KND95005.1 - 2.8 7.3 14.3 20 4.6 0.7 4.4 4 1 0 4 4 4 0 Transcription factor zinc-finger zinc_ribbon_9 PF14369.6 KND95005.1 - 4.7 7.6 7.6 32 4.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon DZR PF12773.7 KND95005.1 - 5.2 7.2 10.3 11 6.2 1.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 KND95005.1 - 8 6.5 6.2 73 3.4 0.3 3.7 4 0 0 4 4 4 0 PhnA Zinc-Ribbon CAP_GLY PF01302.25 KND95006.1 - 5.1e-16 58.4 0.6 1.2e-15 57.2 0.4 1.7 2 0 0 2 2 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KND95006.1 - 5.8e-06 26.0 10.8 0.0014 18.4 1.7 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle Spc7 PF08317.11 KND95006.1 - 0.006 15.5 22.0 1.2 8.0 0.1 3.2 2 1 1 3 3 3 3 Spc7 kinetochore protein DivIC PF04977.15 KND95006.1 - 0.02 14.7 0.2 0.02 14.7 0.2 4.1 5 0 0 5 5 5 0 Septum formation initiator Med4 PF10018.9 KND95006.1 - 0.054 13.2 7.2 0.065 12.9 0.6 2.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 WSD PF15613.6 KND95006.1 - 0.17 12.4 2.1 0.3 11.6 0.1 2.4 3 0 0 3 3 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MscS_porin PF12795.7 KND95006.1 - 0.25 10.9 17.1 0.065 12.8 1.6 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain C1_2 PF03107.16 KND95006.1 - 0.49 10.8 1.4 30 5.0 0.2 2.3 2 0 0 2 2 2 0 C1 domain DUF812 PF05667.11 KND95006.1 - 0.87 8.4 22.5 0.096 11.6 13.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) GspL_C PF12693.7 KND95006.1 - 1.3 8.9 4.9 5.8 6.7 0.3 2.5 1 1 1 2 2 2 0 GspL periplasmic domain FAM76 PF16046.5 KND95006.1 - 2.1 7.6 12.4 28 3.9 7.7 3.0 2 1 0 2 2 2 0 FAM76 protein Fez1 PF06818.15 KND95006.1 - 2.1 8.7 26.5 27 5.1 0.8 3.3 1 1 2 3 3 2 0 Fez1 DUF4407 PF14362.6 KND95006.1 - 2.3 7.5 17.6 26 4.0 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) XLF PF09302.11 KND95006.1 - 2.4 8.3 8.2 40 4.3 0.2 3.7 3 1 1 4 4 4 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component PEARLI-4 PF05278.12 KND95006.1 - 3.2 7.3 11.0 11 5.4 4.9 2.4 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) MAD PF05557.13 KND95006.1 - 3.2 6.0 24.4 0.43 8.9 16.0 2.4 3 0 0 3 3 3 0 Mitotic checkpoint protein Fib_alpha PF08702.10 KND95006.1 - 5.4 7.2 12.9 1.9 8.7 2.3 3.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family BAR PF03114.18 KND95006.1 - 5.8 6.5 13.3 0.045 13.4 0.8 2.8 2 1 1 3 3 3 0 BAR domain DUF1664 PF07889.12 KND95006.1 - 7.9 6.5 10.0 4.8 7.2 2.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF5082 PF16888.5 KND95006.1 - 8.1 6.7 8.8 3.2 8.1 0.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 KND95006.1 - 9.5 6.6 21.4 10 6.5 0.6 4.7 4 1 1 5 5 5 0 Csm1 N-terminal domain HEAT_2 PF13646.6 KND95007.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats HHH_6 PF14579.6 KND95007.1 - 0.071 13.4 0.0 3.7 7.9 0.3 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HEAT PF02985.22 KND95007.1 - 0.08 13.2 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat THF_DHG_CYH PF00763.23 KND95009.1 - 4.7e-25 88.1 0.0 7.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KND95009.1 - 1.7e-13 50.2 0.2 1.2e-08 34.4 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RE_EcoO109I PF14511.6 KND95010.1 - 0.051 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I GMC_oxred_N PF00732.19 KND95011.1 - 9.4e-39 133.5 0.7 1.6e-38 132.8 0.7 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KND95011.1 - 2.6e-29 102.6 0.2 9.1e-29 100.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KND95011.1 - 2.5e-07 30.1 0.5 1.3e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KND95011.1 - 4.2e-07 29.5 0.3 1.6e-05 24.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND95011.1 - 0.00042 20.5 0.1 0.0036 17.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KND95011.1 - 0.001 18.4 0.3 0.0018 17.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND95011.1 - 0.0054 16.4 9.0 0.18 11.3 8.7 3.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KND95011.1 - 0.034 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 KND95011.1 - 0.061 12.6 0.3 0.14 11.3 0.3 1.6 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KND95011.1 - 0.075 12.4 0.5 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KND95011.1 - 0.12 11.9 1.4 0.27 10.8 1.4 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDEase_I PF00233.19 KND95012.1 - 8.3e-62 209.0 0.2 1.2e-61 208.4 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_M16_M PF16187.5 KND95013.1 - 5.5e-94 314.6 0.5 8.5e-94 314.0 0.5 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KND95013.1 - 3.6e-33 114.7 0.3 1e-32 113.2 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KND95013.1 - 6.6e-33 114.3 0.0 3.6e-16 59.7 0.0 3.9 5 0 0 5 5 5 2 Peptidase M16 inactive domain MPP6 PF10175.9 KND95014.1 - 1.6e-06 28.7 14.9 6.4e-06 26.7 11.6 2.7 1 1 1 2 2 2 1 M-phase phosphoprotein 6 NUDIX_2 PF13869.6 KND95015.1 - 6.9e-75 250.8 0.0 6.3e-59 198.7 0.0 2.1 1 1 1 2 2 2 2 Nucleotide hydrolase UPF0047 PF01894.17 KND95016.1 - 1.5e-36 125.1 0.0 2.3e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 KND95016.1 - 4.8e-15 55.3 0.6 7.9e-15 54.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger domain eRF1_2 PF03464.15 KND95017.1 - 1.1e-46 158.4 0.0 1.9e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KND95017.1 - 4.5e-40 136.7 0.4 8.8e-40 135.7 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KND95017.1 - 2.7e-21 75.9 0.0 4.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KND95017.1 - 8.6e-10 39.0 0.7 3.2e-09 37.2 0.0 2.2 3 0 0 3 3 3 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KND95017.1 - 8.5e-09 35.8 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 KND95018.1 - 4e-37 127.1 0.6 5e-37 126.9 0.6 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF2428 PF10350.9 KND95019.1 - 5.7e-29 101.2 0.0 1.2e-28 100.2 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KND95019.1 - 0.017 15.3 0.1 1.8 9.1 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat YmgB PF10798.8 KND95019.1 - 0.13 12.1 0.1 0.34 10.8 0.1 1.7 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF2428 PF10350.9 KND95020.1 - 1.5e-27 96.6 0.2 2.8e-27 95.7 0.2 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_EZ PF13513.6 KND95020.1 - 3.7e-05 24.1 0.8 0.16 12.5 0.1 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.22 KND95020.1 - 0.00011 22.1 4.3 0.46 10.9 0.1 5.1 5 0 0 5 5 5 2 HEAT repeat DUF3074 PF11274.8 KND95021.1 - 9.8e-58 195.2 2.1 2.5e-57 193.9 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) VASt PF16016.5 KND95021.1 - 2e-33 115.9 0.4 6.6e-33 114.3 0.4 2.0 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KND95021.1 - 1.1e-13 51.5 7.6 1.5e-13 51.0 0.0 2.5 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 KND95021.1 - 3.2e-05 24.4 0.1 0.00013 22.4 0.1 2.1 1 0 0 1 1 1 1 PH domain BAR PF03114.18 KND95021.1 - 0.00014 21.6 0.0 0.00014 21.6 0.0 2.4 2 0 0 2 2 2 1 BAR domain GRAM PF02893.20 KND95021.1 - 0.0074 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain VEG PF06257.11 KND95021.1 - 0.13 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Biofilm formation stimulator VEG MCU PF04678.13 KND95021.1 - 1.1 9.3 8.0 3.2 7.8 8.0 1.8 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2151 PF10221.9 KND95021.1 - 5 5.6 10.0 7.5 5.0 10.0 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3729 PF12526.8 KND95021.1 - 8.7 7.9 8.7 1.4 10.5 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) Glyco_transf_22 PF03901.17 KND95022.1 - 8.3e-57 193.3 20.3 1.2e-56 192.8 20.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ribosomal_L1 PF00687.21 KND95023.1 - 1e-38 133.1 0.3 1.3e-38 132.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.21 KND95024.1 - 3.6e-74 248.0 0.0 4e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KND95024.1 - 6.1e-15 55.5 0.0 8.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KND95024.1 - 6.5e-14 51.8 0.0 7.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KND95024.1 - 4e-12 46.0 0.3 3.8e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KND95024.1 - 1.6e-11 44.0 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KND95024.1 - 9.8e-09 34.9 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KND95024.1 - 6.1e-07 29.5 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KND95024.1 - 7.1e-05 22.4 0.0 0.0059 16.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KND95024.1 - 0.0076 15.3 0.1 0.033 13.2 0.1 2.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 KND95024.1 - 0.0089 15.6 0.7 0.034 13.7 0.7 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B TerB_C PF15615.6 KND95024.1 - 0.068 13.5 0.1 0.093 13.0 0.1 1.1 1 0 0 1 1 1 0 TerB-C domain AAA_18 PF13238.6 KND95024.1 - 0.12 12.9 0.1 0.3 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Skp1 PF01466.19 KND95025.1 - 3.5e-29 100.7 0.4 3.5e-29 100.7 0.4 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KND95025.1 - 4e-18 65.3 0.1 9.8e-18 64.1 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain WHIM1 PF15612.6 KND95026.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 NOA36 PF06524.12 KND95026.1 - 1.5 8.0 7.3 2.7 7.2 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L2_C PF03947.18 KND95027.1 - 1.1e-40 138.7 4.9 1.8e-40 138.1 4.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KND95027.1 - 6.8e-09 35.6 0.1 9.7e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 Ribosomal Proteins L2, RNA binding domain NRDE-2 PF08424.10 KND95028.1 - 1.3e-99 333.4 2.8 6.5e-98 327.8 0.8 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 KND95028.1 - 0.00012 22.6 0.6 4.6 8.3 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat adh_short PF00106.25 KND95029.1 - 1.4e-31 109.4 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND95029.1 - 5.3e-23 81.8 0.0 6.8e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KND95029.1 - 7.7e-13 48.7 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KND95029.1 - 0.00061 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 KND95029.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F420_oxidored PF03807.17 KND95029.1 - 0.0038 17.8 0.0 0.79 10.3 0.1 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 KND95029.1 - 0.012 15.6 0.2 0.036 14.0 0.2 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 KND95029.1 - 0.012 15.4 0.9 0.027 14.2 0.4 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 KND95029.1 - 0.012 15.5 0.4 0.012 15.5 0.4 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KND95029.1 - 0.013 16.0 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KND95029.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KND95029.1 - 0.079 12.2 0.1 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KND95029.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KND95029.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 KND95029.1 - 0.12 12.2 0.2 0.21 11.4 0.2 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.15 KND95029.1 - 0.12 12.5 0.4 0.32 11.1 0.0 2.0 2 1 1 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KND95029.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF3669 PF12417.8 KND95030.1 - 1.5e-22 79.6 0.1 2.8e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger protein SURF4 PF02077.15 KND95031.1 - 4.1e-97 324.9 6.3 4.7e-97 324.8 6.3 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.11 KND95031.1 - 1.8 8.8 8.9 0.54 10.4 1.7 2.8 2 1 0 3 3 3 0 HR-like lesion-inducing HhH-GPD PF00730.25 KND95032.1 - 0.00097 19.6 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.22 KND95033.1 - 4.3e-19 68.1 0.3 8.2e-19 67.2 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KND95033.1 - 2.9e-05 23.6 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KND95033.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4523 PF15023.6 KND95033.1 - 0.07 12.9 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) SWIM PF04434.17 KND95034.1 - 0.18 11.5 1.6 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 SWIM zinc finger Pkinase_Tyr PF07714.17 KND95035.1 - 0.0056 16.0 0.3 0.049 12.9 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Zn_clus PF00172.18 KND95037.1 - 4.7 7.4 12.0 0.16 12.1 5.1 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KND95038.1 - 4.7e-28 98.7 0.3 6.2e-28 98.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KND95038.1 - 0.031 13.4 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 CsiD His_Phos_2 PF00328.22 KND95039.1 - 4.4e-46 158.0 0.0 5.3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DSPn PF14671.6 KND95040.1 - 4e-40 137.5 0.0 6.1e-38 130.4 0.0 2.5 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KND95040.1 - 1.7e-16 60.2 0.0 3.9e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KND95040.1 - 5.7e-06 26.1 1.2 1.1e-05 25.2 0.0 1.9 2 1 0 2 2 2 1 Protein-tyrosine phosphatase HeLo PF14479.6 KND95041.1 - 3.5e-54 183.8 0.1 8.8e-54 182.5 0.1 1.6 2 0 0 2 2 2 1 Prion-inhibition and propagation ketoacyl-synt PF00109.26 KND95042.1 - 4.8e-60 203.2 2.6 4.8e-60 203.2 2.6 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KND95042.1 - 7.2e-37 126.0 1.7 2.1e-36 124.5 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KND95042.1 - 9.5e-05 21.9 1.5 0.00026 20.4 0.2 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KND95042.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Hydin_ADK PF17213.3 KND95043.1 - 0.37 11.0 12.1 0.47 10.7 12.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Macoilin PF09726.9 KND95043.1 - 2.2 6.8 15.4 2.7 6.4 15.4 1.0 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 KND95043.1 - 2.3 7.3 11.9 3.1 6.9 11.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1917 PF08939.10 KND95044.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) VP_N-CPKC PF11475.8 KND95044.1 - 0.63 10.0 4.5 5.9 6.9 1.5 2.3 2 0 0 2 2 2 0 Virion protein N terminal domain UDPGP PF01704.18 KND95046.1 - 9.7e-192 637.1 0.0 1.1e-191 636.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Leo1 PF04004.13 KND95047.1 - 7.9e-32 110.4 2.2 8.5e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein NBD_C PF17042.5 KND95047.1 - 0.08 13.4 0.2 0.16 12.5 0.2 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Mob1_phocein PF03637.17 KND95048.1 - 2.1e-42 145.0 0.0 4.7e-42 143.9 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family MTS PF05175.14 KND95049.1 - 0.00037 20.1 0.0 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Cullin PF00888.22 KND95050.1 - 1.6e-194 648.0 6.0 1.9e-194 647.8 6.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KND95050.1 - 6.7e-15 54.9 0.1 2.3e-14 53.2 0.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain SWIM PF04434.17 KND95051.1 - 0.058 13.1 0.4 0.49 10.1 0.1 2.3 2 0 0 2 2 2 0 SWIM zinc finger LSM PF01423.22 KND95052.1 - 1.3e-18 66.5 0.1 1.6e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND95052.1 - 0.0011 19.1 0.1 0.0015 18.6 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain HlyD_D23 PF16576.5 KND95052.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion API5 PF05918.11 KND95052.1 - 8.5 5.1 7.2 11 4.7 7.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ctr PF04145.15 KND95054.1 - 1.9e-33 116.2 5.4 3.1e-33 115.5 5.4 1.3 1 1 0 1 1 1 1 Ctr copper transporter family NUDIX PF00293.28 KND95055.1 - 6.6e-09 35.9 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain FAA_hydrolase PF01557.18 KND95056.1 - 1.8e-52 178.2 0.0 2e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 KND95057.1 - 4.5e-61 204.9 0.0 5.1e-61 204.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KND95057.1 - 2.3e-05 24.0 0.1 3.6e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KND95057.1 - 9e-05 22.4 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DZR PF12773.7 KND95057.1 - 0.065 13.3 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon Cupin_1 PF00190.22 KND95057.1 - 0.091 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Cupin EXS PF03124.14 KND95059.1 - 1.5e-115 386.0 7.7 1.7e-115 385.9 7.7 1.0 1 0 0 1 1 1 1 EXS family Pet100 PF09803.9 KND95060.1 - 5.7e-19 68.4 0.8 7.2e-19 68.1 0.8 1.3 1 0 0 1 1 1 1 Pet100 TMIE PF16038.5 KND95060.1 - 0.41 10.5 1.9 0.53 10.2 1.9 1.2 1 0 0 1 1 1 0 TMIE protein Nnf1 PF03980.14 KND95062.1 - 3.8e-33 114.2 2.5 4.3e-33 114.0 0.9 1.8 1 1 1 2 2 2 1 Nnf1 Sigma70_ner PF04546.13 KND95062.1 - 0.054 13.4 3.1 1.5 8.7 0.0 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region HAUS6_N PF14661.6 KND95062.1 - 0.076 12.6 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PCP PF02429.15 KND95062.1 - 0.15 12.4 1.3 0.47 10.8 1.0 1.8 2 0 0 2 2 2 0 Peridinin-chlorophyll A binding protein DUF1640 PF07798.11 KND95063.1 - 3.2e-47 160.8 7.4 3.2e-47 160.8 7.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) S1FA PF04689.13 KND95063.1 - 0.098 12.8 0.6 0.2 11.8 0.6 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA TMEMspv1-c74-12 PF11044.8 KND95063.1 - 0.2 11.7 0.9 0.44 10.6 0.9 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Connexin PF00029.19 KND95063.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.9 3 1 0 3 3 3 0 Connexin EMC3_TMCO1 PF01956.16 KND95063.1 - 0.63 9.7 4.3 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1664 PF07889.12 KND95063.1 - 1.5 8.9 5.5 1.7 8.7 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PUF PF00806.19 KND95064.1 - 2.8e-60 196.8 9.2 2.2e-07 30.2 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 KND95064.1 - 0.0053 17.1 5.4 9.8 6.5 0.0 4.0 1 1 2 4 4 4 2 CPL (NUC119) domain LOB PF03195.14 KND95064.1 - 0.067 13.8 1.1 11 6.7 0.0 3.2 3 0 0 3 3 3 0 Lateral organ boundaries (LOB) domain DUF445 PF04286.12 KND95064.1 - 0.31 10.8 5.5 0.22 11.3 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF737 PF05300.11 KND95064.1 - 8.4 6.7 9.3 9.5 6.5 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF737) Sid-5 PF17204.3 KND95065.1 - 0.065 13.4 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 Sid-5 family EphA2_TM PF14575.6 KND95065.1 - 0.19 12.6 0.0 0.34 11.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KND95065.1 - 6.7 6.2 5.3 15 5.1 5.1 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Zn_clus PF00172.18 KND95066.1 - 7.6e-13 48.3 29.4 4.6e-08 33.1 11.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KND95066.1 - 1.8e-05 23.9 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_bd PF14376.6 KND95066.1 - 1 9.3 3.1 2.1 8.3 3.1 1.5 1 0 0 1 1 1 0 Haem-binding domain zf-C2H2 PF00096.26 KND95068.1 - 7.5e-07 29.3 22.7 1.8e-05 24.9 3.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KND95068.1 - 4.5e-05 23.9 2.5 4.5e-05 23.9 2.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KND95068.1 - 7.1e-05 23.1 4.2 7.1e-05 23.1 4.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KND95068.1 - 0.00021 21.5 1.1 0.00068 19.9 1.1 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KND95068.1 - 0.002 18.4 5.9 0.0097 16.2 5.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KND95068.1 - 0.014 15.4 2.3 0.031 14.3 2.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 KND95068.1 - 0.039 14.3 3.4 0.14 12.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KND95068.1 - 0.33 11.6 9.3 0.27 11.9 0.8 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-TRAF PF02176.18 KND95068.1 - 0.38 11.5 7.9 0.19 12.4 3.9 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 KND95068.1 - 2.2 8.7 8.2 7.2 7.0 6.2 2.7 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 KND95068.1 - 2.2 8.3 5.3 0.59 10.1 1.8 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ARS2 PF04959.13 KND95068.1 - 7 7.0 7.6 1.8 8.9 1.2 3.0 3 0 0 3 3 3 0 Arsenite-resistance protein 2 DUF629 PF04780.12 KND95068.1 - 7.9 4.9 8.1 3.3 6.1 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) NTF2 PF02136.20 KND95069.1 - 8.1e-25 87.7 0.9 1.3e-24 87.1 0.9 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KND95069.1 - 8.4e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 KND95070.1 - 1.6e-53 180.7 0.0 1.3e-42 145.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 KND95070.1 - 1.6e-25 89.3 0.5 4.2e-25 87.9 0.5 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 KND95070.1 - 1.1e-12 47.5 0.1 6.4e-09 35.5 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KND95070.1 - 2.4e-11 44.3 1.8 0.00013 22.4 0.2 4.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KND95070.1 - 8.6e-07 29.6 0.1 0.004 17.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KND95070.1 - 2.2e-06 27.7 0.2 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KND95070.1 - 2.9e-06 27.6 0.7 0.012 15.9 0.1 3.5 2 2 1 3 3 3 2 AAA domain TsaE PF02367.17 KND95070.1 - 9.9e-06 25.6 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 KND95070.1 - 1.1e-05 25.3 0.0 0.022 14.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KND95070.1 - 1.2e-05 24.9 0.0 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KND95070.1 - 2.6e-05 24.2 0.1 0.084 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KND95070.1 - 4.2e-05 23.7 0.3 0.48 10.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 KND95070.1 - 0.00029 20.9 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KND95070.1 - 0.0014 18.0 0.1 0.34 10.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 KND95070.1 - 0.0023 17.4 0.2 1.1 8.6 0.1 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 KND95070.1 - 0.0024 17.6 0.0 0.09 12.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 KND95070.1 - 0.003 16.8 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activ_2 PF14532.6 KND95070.1 - 0.0032 17.6 0.0 0.092 12.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 KND95070.1 - 0.0045 17.4 0.0 4.7 7.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KND95070.1 - 0.0049 17.0 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) SKI PF01202.22 KND95070.1 - 0.0075 16.4 0.1 0.59 10.2 0.1 2.4 2 0 0 2 2 2 1 Shikimate kinase IstB_IS21 PF01695.17 KND95070.1 - 0.01 15.6 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 KND95070.1 - 0.013 15.0 2.5 1.9 8.0 0.1 3.6 3 1 1 4 4 4 0 AAA domain ATPase PF06745.13 KND95070.1 - 0.021 14.2 0.3 5.6 6.2 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 KND95070.1 - 0.026 14.8 0.0 5 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KND95070.1 - 0.049 14.1 0.1 9.3 6.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 KND95070.1 - 0.069 13.0 0.2 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 KND95070.1 - 0.077 13.4 1.5 3 8.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 KND95070.1 - 0.089 11.9 0.0 0.83 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KND95070.1 - 0.1 12.5 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 KND95070.1 - 0.12 12.0 0.6 13 5.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KND95070.1 - 0.25 10.5 0.1 18 4.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Inositol_P PF00459.25 KND95071.1 - 1.8e-38 132.6 0.1 3.2e-38 131.8 0.1 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family RRS1 PF04939.12 KND95074.1 - 3.5e-59 199.3 1.4 4.1e-59 199.1 1.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 KND95075.1 - 1.9e-29 102.4 0.0 3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DAP3 PF10236.9 KND95076.1 - 1.1e-86 290.9 0.0 1.3e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SET PF00856.28 KND95077.1 - 6.5e-09 36.4 0.0 3.5e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 SET domain KH_1 PF00013.29 KND95078.1 - 2.9e-40 135.9 11.0 1.3e-15 57.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KND95078.1 - 9.8e-09 34.9 10.5 0.021 14.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KND95078.1 - 3.7e-07 29.9 8.6 0.027 14.3 0.3 3.8 3 1 1 4 4 4 3 KH domain KH_5 PF13184.6 KND95078.1 - 0.00017 21.6 5.3 0.38 10.9 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KND95078.1 - 0.035 14.1 0.0 14 5.8 0.1 2.9 3 0 0 3 3 3 0 KH-like RNA-binding domain bZIP_1 PF00170.21 KND95079.1 - 6.4e-10 39.0 16.0 1.8e-09 37.6 12.3 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KND95079.1 - 9.7e-07 28.8 8.6 9.7e-07 28.8 8.6 2.5 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 KND95079.1 - 5.1e-05 23.7 13.5 0.00013 22.4 13.2 1.9 1 1 0 1 1 1 1 bZIP Maf transcription factor HeLo PF14479.6 KND95079.1 - 0.13 12.1 5.8 0.34 10.7 5.8 1.7 1 0 0 1 1 1 0 Prion-inhibition and propagation Jnk-SapK_ap_N PF09744.9 KND95079.1 - 0.45 10.7 21.4 0.5 10.6 17.8 2.4 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 FapA PF03961.13 KND95079.1 - 0.83 8.2 9.7 1.2 7.6 9.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 KND95079.1 - 2.2 7.5 13.0 1.7 7.9 10.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CorA PF01544.18 KND95079.1 - 3.2 7.0 7.2 6.8 5.9 7.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sel1 PF08238.12 KND95080.1 - 3.6e-08 33.8 2.8 1.6 9.5 0.0 5.8 6 0 0 6 6 6 3 Sel1 repeat SecA_DEAD PF07517.14 KND95082.1 - 4.4 6.5 9.9 0.17 11.1 3.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain CorA PF01544.18 KND95085.1 - 0.019 14.3 8.9 0.046 13.0 8.9 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 KND95087.1 - 9.2e-116 387.7 6.9 1.1e-115 387.6 6.9 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein P5CR_dimer PF14748.6 KND95088.1 - 8.7e-33 112.7 2.7 1.6e-32 111.9 2.7 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KND95088.1 - 4.3e-11 43.2 0.6 1.1e-08 35.6 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF2040 PF09745.9 KND95089.1 - 6.9e-39 132.6 23.8 6.9e-39 132.6 23.8 3.6 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) MMS1_N PF10433.9 KND95090.1 - 3.3e-146 487.8 0.0 5.2e-146 487.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KND95090.1 - 2.5e-96 322.8 0.0 3.7e-95 318.9 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region UBM PF14377.6 KND95090.1 - 0.09 12.3 3.5 0.55 9.8 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin binding region ANAPC4_WD40 PF12894.7 KND95090.1 - 0.18 12.1 0.0 0.72 10.2 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Lectin_leg-like PF03388.13 KND95091.1 - 3.4e-66 222.9 0.0 4.6e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 KND95091.1 - 2.2e-05 24.1 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 KND95091.1 - 0.0024 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 zf-HC5HC2H_2 PF13832.6 KND95094.1 - 6e-18 65.0 1.8 6e-18 65.0 1.8 4.3 4 1 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 KND95094.1 - 1.2e-14 54.3 0.0 2.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KND95094.1 - 7.5e-12 45.3 3.2 7.5e-12 45.3 3.2 4.7 4 1 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 KND95094.1 - 5.7e-10 38.9 24.8 1.7e-06 27.8 9.5 6.2 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 KND95094.1 - 3.7e-08 32.8 4.8 3.7e-08 32.8 4.8 4.8 7 0 0 7 7 7 1 PHD-finger C1_1 PF00130.22 KND95094.1 - 0.004 17.0 1.7 0.004 17.0 1.7 5.6 5 1 1 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 KND95094.1 - 0.006 16.8 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain ELM2 PF01448.24 KND95094.1 - 0.015 16.1 2.6 0.027 15.2 0.4 2.6 2 0 0 2 2 2 0 ELM2 domain C1_2 PF03107.16 KND95094.1 - 0.032 14.5 0.4 0.032 14.5 0.4 6.8 8 0 0 8 8 8 0 C1 domain Abhydrolase_1 PF00561.20 KND95095.1 - 1.6e-10 41.1 0.0 4.1e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND95095.1 - 2.2e-08 33.7 0.0 3.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 KND95095.1 - 0.0017 17.3 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KND95095.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KND95095.1 - 0.053 13.1 0.0 0.19 11.3 0.0 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pil1 PF13805.6 KND95096.1 - 3e-110 367.9 0.5 4.9e-110 367.2 0.5 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Pyrophosphatase PF00719.19 KND95096.1 - 1.9e-57 193.6 0.2 2.9e-57 193.0 0.2 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.9 KND95097.1 - 3.3e-22 78.4 1.3 4.6e-22 77.9 1.3 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.13 KND95098.1 - 5.7e-17 61.4 0.9 2.5e-15 56.2 0.2 2.8 3 0 0 3 3 3 1 Sec20 ArAE_2 PF10334.9 KND95098.1 - 0.027 14.3 0.2 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Aldolase_II PF00596.21 KND95099.1 - 3.6e-37 128.1 0.0 4.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LcnG-beta PF11632.8 KND95099.1 - 0.095 12.7 1.3 0.23 11.4 1.3 1.6 1 0 0 1 1 1 0 Lactococcin G-beta Hexokinase_2 PF03727.16 KND95100.1 - 1.4e-83 280.0 0.0 1.9e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KND95100.1 - 1.9e-69 233.5 0.0 5.7e-69 232.0 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Ank_2 PF12796.7 KND95101.1 - 0.15 12.7 0.0 3.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ribophorin_I PF04597.14 KND95102.1 - 2.2e-150 501.7 0.6 2.5e-150 501.5 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I Pkinase PF00069.25 KND95105.1 - 6e-16 58.6 0.0 7.1e-10 38.7 0.0 3.2 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KND95105.1 - 1.2e-08 34.6 0.0 6.7e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase GSH_synth_ATP PF03917.17 KND95106.1 - 2.2e-123 411.8 0.0 1.1e-122 409.5 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KND95106.1 - 4.4e-32 110.6 0.0 7.3e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KND95107.1 - 2.5e-40 138.3 0.0 4.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KND95107.1 - 1.4e-22 80.1 0.0 9e-22 77.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95107.1 - 9.1e-07 29.0 0.0 3e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TAP_C PF03943.13 KND95109.1 - 1.9e-18 65.8 0.3 7.3e-18 64.0 0.2 2.0 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 KND95109.1 - 1.6e-05 25.2 0.0 0.0061 16.9 0.0 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 KND95109.1 - 4.1e-05 24.1 0.0 0.00017 22.1 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 KND95109.1 - 0.00099 18.9 0.1 0.0059 16.4 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif LRR_9 PF14580.6 KND95109.1 - 0.0023 17.4 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KND95109.1 - 0.17 12.0 0.3 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat Ank_2 PF12796.7 KND95110.1 - 9e-46 154.4 2.7 1.1e-13 51.5 0.0 9.1 6 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND95110.1 - 2.3e-33 114.1 2.2 0.00014 22.3 0.0 10.7 9 2 2 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND95110.1 - 3.7e-31 103.7 4.9 0.00065 20.0 0.0 13.7 15 0 0 15 15 15 6 Ankyrin repeat Ank_5 PF13857.6 KND95110.1 - 8.7e-28 96.0 2.5 0.002 18.4 0.0 10.5 10 1 1 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 KND95110.1 - 2.2e-23 81.6 17.2 0.00037 20.8 0.0 10.5 11 0 0 11 11 11 5 Ankyrin repeat DUF1772 PF08592.11 KND95111.1 - 2.2e-06 28.0 1.8 2.2e-06 28.0 1.8 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) RskA PF10099.9 KND95111.1 - 1 9.6 12.1 2.5 8.3 5.5 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA HMG_box_2 PF09011.10 KND95112.1 - 5.2e-05 23.8 0.1 5.2e-05 23.8 0.1 2.3 3 0 0 3 3 3 1 HMG-box domain HMG_box PF00505.19 KND95112.1 - 0.001 19.5 0.1 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box LCD1 PF09798.9 KND95112.1 - 0.056 12.0 0.2 0.073 11.6 0.2 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Cpn60_TCP1 PF00118.24 KND95113.1 - 2.7e-154 514.4 7.2 3.1e-154 514.3 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UBA PF00627.31 KND95114.1 - 3.4e-25 87.5 9.2 4.9e-13 48.7 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 KND95114.1 - 6.7e-24 83.4 15.3 1e-23 82.8 15.3 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 KND95114.1 - 2e-20 72.3 0.1 3.6e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KND95114.1 - 3.3e-07 30.0 0.2 5.6e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 KND95114.1 - 0.0011 18.7 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain MCM_N PF14551.6 KND95114.1 - 0.049 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Rad60-SLD_2 PF13881.6 KND95114.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Clathrin_H_link PF13838.6 KND95114.1 - 0.062 13.2 2.1 0.28 11.1 0.3 2.6 2 0 0 2 2 2 0 Clathrin-H-link Ubiquitin_5 PF18037.1 KND95114.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 KND95114.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain FTCD_C PF04961.12 KND95114.1 - 0.18 11.5 4.8 1.9 8.2 0.6 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase WIYLD PF10440.9 KND95114.1 - 0.26 11.1 0.5 4 7.3 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain MAGE_N PF12440.8 KND95114.1 - 0.69 10.6 0.0 0.69 10.6 0.0 3.4 3 1 1 4 4 2 0 Melanoma associated antigen family N terminal MCPVI PF02993.14 KND95114.1 - 1.2 8.9 6.7 0.39 10.5 2.6 2.1 2 0 0 2 2 2 0 Minor capsid protein VI BRE1 PF08647.11 KND95115.1 - 7e-28 96.6 11.7 7e-28 96.6 11.7 6.9 4 2 3 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KND95115.1 - 8.8e-09 35.1 7.7 1.5e-08 34.4 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KND95115.1 - 1.3e-08 34.6 6.9 2.1e-08 33.9 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KND95115.1 - 3.1e-08 33.4 11.0 5.6e-08 32.5 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KND95115.1 - 1e-07 31.6 9.1 2e-07 30.7 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KND95115.1 - 7.3e-07 29.1 5.7 1.5e-06 28.1 5.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KND95115.1 - 1.6e-06 28.0 10.1 2.7e-06 27.2 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KND95115.1 - 6.5e-06 26.4 8.5 6.5e-06 26.4 8.5 1.7 2 0 0 2 2 1 1 Ring finger domain JIP_LZII PF16471.5 KND95115.1 - 0.0015 18.7 0.9 0.0015 18.7 0.9 6.9 6 2 1 7 7 7 1 JNK-interacting protein leucine zipper II zf-C3HC4_4 PF15227.6 KND95115.1 - 0.008 16.3 6.4 0.016 15.4 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING bZIP_1 PF00170.21 KND95115.1 - 0.039 14.0 0.6 0.039 14.0 0.6 8.9 6 2 5 11 11 10 0 bZIP transcription factor MLD PF11647.8 KND95115.1 - 0.074 13.3 2.6 0.66 10.3 0.3 3.3 2 1 1 3 3 3 0 Membrane Localization Domain zf-RING_6 PF14835.6 KND95115.1 - 0.12 12.2 2.1 0.29 11.0 2.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KND95115.1 - 0.28 11.0 7.1 1.2 9.0 7.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 KND95115.1 - 0.65 10.1 3.6 2 8.6 3.6 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 KND95115.1 - 1.5 8.7 4.2 3.6 7.4 4.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger FYVE PF01363.21 KND95115.1 - 1.8 8.7 11.2 14 5.9 11.1 2.2 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.7 KND95115.1 - 3.1 8.2 13.2 1.9 8.8 8.2 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Retrotrans_gag PF03732.17 KND95115.1 - 3.4 8.0 10.5 2.8 8.3 0.2 4.0 3 0 0 3 3 3 0 Retrotransposon gag protein APG6_N PF17675.1 KND95115.1 - 7.4 7.1 79.7 0.2 12.2 17.4 6.3 3 1 3 6 6 5 0 Apg6 coiled-coil region MnhB PF04039.13 KND95116.1 - 2.8 8.3 5.7 1.1 9.5 1.0 2.1 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Myb_DNA-bind_7 PF15963.5 KND95117.1 - 3.3e-24 84.6 0.4 3.3e-24 84.6 0.4 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 KND95117.1 - 0.00018 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KND95117.1 - 0.02 15.1 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Repressor_Mnt PF11423.8 KND95117.1 - 4 7.3 5.7 0.49 10.2 0.6 2.3 2 0 0 2 2 2 0 Regulatory protein Mnt U3_snoRNA_assoc PF08297.11 KND95118.1 - 2.6e-16 60.1 2.3 2.6e-16 60.1 2.3 4.0 2 1 2 4 4 4 1 U3 snoRNA associated TPR_4 PF07721.14 KND95119.1 - 1.2e-06 28.6 0.7 0.11 13.2 0.0 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KND95119.1 - 1.3e-06 28.8 0.4 6.2e-05 23.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KND95119.1 - 2e-06 27.4 0.5 0.044 13.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KND95119.1 - 6.8e-06 26.2 0.1 1.9e-05 24.8 0.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KND95119.1 - 8.1e-06 26.4 6.6 0.0028 18.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KND95119.1 - 2.6e-05 24.7 6.7 0.06 14.2 0.5 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND95119.1 - 0.00017 21.8 1.1 0.13 12.6 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KND95119.1 - 0.00052 20.0 0.0 1 9.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KND95119.1 - 0.01 15.8 1.4 5.6 7.2 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KND95119.1 - 0.015 15.0 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 KND95119.1 - 0.043 14.5 1.8 15 6.4 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KND95119.1 - 0.061 13.2 0.0 6.4 6.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KND95119.1 - 0.097 12.6 3.3 13 5.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PH_10 PF15411.6 KND95120.1 - 2.4e-29 102.1 0.0 4.7e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KND95120.1 - 2.8e-14 53.8 0.0 4.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KND95120.1 - 1.6e-10 41.1 0.1 5.9e-10 39.3 0.1 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KND95120.1 - 0.00056 20.2 5.8 0.00099 19.4 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KND95120.1 - 0.0029 17.5 5.6 0.0049 16.8 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KND95120.1 - 0.018 15.3 2.7 0.04 14.2 2.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KND95120.1 - 0.022 14.6 4.7 0.041 13.7 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KND95120.1 - 0.082 12.5 6.8 0.02 14.5 3.3 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 KND95120.1 - 0.086 13.2 4.4 0.16 12.3 4.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 KND95120.1 - 0.099 12.5 5.6 0.19 11.7 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KND95120.1 - 0.1 12.4 4.2 0.2 11.4 4.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger PH PF00169.29 KND95120.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF1147 PF06615.11 KND95120.1 - 0.19 11.8 0.6 0.55 10.3 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-C3H2C3 PF17122.5 KND95120.1 - 1.5 8.9 5.1 3.4 7.8 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger Pkinase PF00069.25 KND95122.1 - 1.8e-69 234.1 0.0 2.3e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95122.1 - 1.7e-31 109.5 0.0 2.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KND95122.1 - 2.5e-14 53.7 0.6 8.2e-14 52.0 0.3 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KND95122.1 - 8.8e-10 38.4 0.1 2.7e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KND95122.1 - 0.001 18.1 0.3 0.0022 17.0 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KND95122.1 - 0.0041 16.8 1.2 1.2 8.8 0.1 3.2 3 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KND95122.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KND95122.1 - 0.029 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KND95122.1 - 0.038 13.6 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CDH-cyt PF16010.5 KND95123.1 - 7.8e-22 77.8 0.5 1.7e-21 76.7 0.5 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KND95123.1 - 2.2e-06 27.9 0.1 5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KND95123.1 - 2.9e-06 27.0 4.8 2.9e-06 27.0 4.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) CDH-cyt PF16010.5 KND95124.1 - 7.8e-22 77.8 0.5 1.7e-21 76.7 0.5 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KND95124.1 - 2.2e-06 27.9 0.1 5e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 KND95124.1 - 2.9e-06 27.0 4.8 2.9e-06 27.0 4.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SUZ PF12752.7 KND95125.1 - 0.00022 21.9 4.6 0.00022 21.9 4.6 3.9 2 1 1 3 3 3 1 SUZ domain U1snRNP70_N PF12220.8 KND95125.1 - 4.1 8.1 8.3 0.66 10.7 1.6 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Fe_hyd_lg_C PF02906.14 KND95128.1 - 2.4e-50 171.5 0.0 5.3e-50 170.3 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.6 KND95130.1 - 1.6e-06 28.3 11.3 5e-06 26.7 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KND95130.1 - 3.9e-06 26.7 0.7 0.01 15.8 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KND95130.1 - 9.3e-06 25.8 0.5 9.3e-06 25.8 0.5 3.3 4 0 0 4 4 4 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KND95130.1 - 0.00023 21.7 6.1 0.24 12.1 0.0 2.8 2 1 0 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 KND95130.1 - 0.00028 21.5 4.9 0.0038 18.0 0.4 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger TSCPD PF12637.7 KND95130.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain zf-C2H2_jaz PF12171.8 KND95130.1 - 0.17 12.2 1.5 2.5 8.5 0.3 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 KND95130.1 - 0.2 11.5 2.8 0.6 9.9 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 KND95130.1 - 0.25 11.1 1.9 0.54 10.1 0.1 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type SPX PF03105.19 KND95130.1 - 0.99 9.2 3.9 1.6 8.6 3.9 1.2 1 0 0 1 1 1 0 SPX domain Pro_isomerase PF00160.21 KND95131.1 - 8.2e-51 172.4 0.1 1.8e-50 171.3 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KND95131.1 - 2e-11 44.2 0.1 0.0016 19.2 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND95131.1 - 3.4e-06 27.3 0.0 0.00061 20.0 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KND95131.1 - 0.0029 16.6 0.5 0.46 9.4 0.1 2.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DAHP_synth_1 PF00793.20 KND95132.1 - 3.8e-100 334.3 0.1 4.7e-100 334.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family OPT PF03169.15 KND95134.1 - 3.6e-117 392.5 30.5 8.4e-69 232.8 18.3 2.1 2 0 0 2 2 2 2 OPT oligopeptide transporter protein CcmD PF04995.14 KND95134.1 - 0.17 12.0 2.9 0.18 11.9 0.2 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) His_biosynth PF00977.21 KND95135.1 - 1.4e-35 122.9 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KND95135.1 - 0.051 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Cmc1 PF08583.10 KND95136.1 - 7.4e-16 57.9 4.3 8.7e-16 57.7 4.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tmemb_14 PF03647.13 KND95137.1 - 1.7e-18 67.1 2.8 2.6e-18 66.6 2.8 1.3 1 1 0 1 1 1 1 Transmembrane proteins 14C CBFD_NFYB_HMF PF00808.23 KND95138.1 - 5.1e-07 29.9 0.4 1e-06 28.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone bZIP_1 PF00170.21 KND95139.1 - 0.0068 16.5 7.7 0.017 15.2 7.8 1.6 1 1 0 1 1 1 1 bZIP transcription factor B12-binding PF02310.19 KND95139.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain RRN3 PF05327.11 KND95140.1 - 1.5e-171 571.8 0.0 1.5e-171 571.8 0.0 1.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 AA_permease_2 PF13520.6 KND95141.1 - 1.9e-30 106.1 24.7 2.4e-30 105.8 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND95141.1 - 2.4e-08 33.0 22.6 5.7e-08 31.8 22.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KND95142.1 - 5.5e-06 25.5 11.5 6.9e-06 25.2 11.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KND95142.1 - 0.00032 19.4 10.4 0.00044 19.0 10.4 1.1 1 0 0 1 1 1 1 Amino acid permease Avidin PF01382.17 KND95142.1 - 0.11 13.0 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Avidin family VIT1 PF01988.19 KND95142.1 - 0.32 10.8 3.5 0.46 10.3 3.5 1.4 1 1 0 1 1 1 0 VIT family Phage_holin_3_6 PF07332.11 KND95142.1 - 6.3 6.9 6.3 2.1 8.4 2.9 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pinin_SDK_memA PF04696.13 KND95143.1 - 8.2e-31 106.8 20.1 1.5e-30 105.9 20.1 1.4 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DUF5383 PF17355.2 KND95143.1 - 0.37 11.2 4.7 0.67 10.3 4.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5383) PHF5 PF03660.14 KND95144.1 - 4e-52 174.8 10.4 4.6e-52 174.6 10.4 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 KND95144.1 - 0.7 7.7 7.8 0.71 7.7 7.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 KND95144.1 - 2.5 8.2 15.6 5.6 7.1 1.9 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pex26 PF07163.12 KND95145.1 - 6.1e-05 22.5 6.1 0.00052 19.4 3.0 2.4 2 0 0 2 2 2 1 Pex26 protein Pro-rich_19 PF15455.6 KND95145.1 - 0.0012 18.0 0.9 0.0018 17.5 0.9 1.2 1 0 0 1 1 1 1 Proline-rich 19 CDC45 PF02724.14 KND95145.1 - 0.0015 16.9 4.4 0.002 16.5 4.4 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF572 PF04502.13 KND95145.1 - 0.022 14.4 12.4 0.035 13.7 12.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1451 PF07295.11 KND95145.1 - 1.2 9.2 10.1 2.4 8.2 10.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain Asp-B-Hydro_N PF05279.11 KND95145.1 - 7.7 6.5 12.4 12 5.9 12.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Haspin_kinase PF12330.8 KND95146.1 - 1.1e-33 116.7 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Ecl1 PF12855.7 KND95147.1 - 1.5e-36 127.2 18.7 1.5e-36 127.2 18.7 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 KND95147.1 - 0.063 13.4 1.6 0.14 12.3 1.6 1.5 1 0 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 KND95147.1 - 0.083 12.4 2.6 0.18 11.3 2.6 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 KND95147.1 - 0.098 13.3 1.0 0.17 12.6 1.0 1.3 1 0 0 1 1 1 0 PLATZ transcription factor DUF2947 PF11163.8 KND95147.1 - 0.12 12.2 0.2 0.18 11.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) PhoLip_ATPase_C PF16212.5 KND95148.1 - 2.3e-81 273.3 21.3 2.3e-81 273.3 21.3 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KND95148.1 - 1.3e-27 95.2 4.0 3.9e-27 93.7 4.0 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KND95148.1 - 1.3e-10 41.2 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KND95148.1 - 6.6e-10 39.6 0.3 3.7e-05 24.1 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KND95148.1 - 3e-07 30.1 0.0 6.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KND95148.1 - 0.0032 17.3 0.3 0.0097 15.7 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 KND95149.1 - 7.4e-23 81.5 0.0 9e-19 68.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND95149.1 - 3.2e-13 50.8 0.1 4.2e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND95149.1 - 1e-05 25.0 0.0 3.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Epimerase PF01370.21 KND95151.1 - 0.00011 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KND95151.1 - 0.017 15.0 0.0 0.068 13.0 0.0 2.0 2 1 0 2 2 2 0 NAD(P)H-binding 3Beta_HSD PF01073.19 KND95151.1 - 0.025 13.6 0.0 0.05 12.6 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KND95151.1 - 0.14 11.2 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KND95151.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase SIR2 PF02146.17 KND95153.1 - 4.9e-25 88.5 0.0 1.6e-24 86.8 0.0 1.8 1 1 0 1 1 1 1 Sir2 family LSM PF01423.22 KND95154.1 - 1.6e-17 62.9 0.1 2e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KND95154.1 - 0.0001 22.3 0.1 0.00014 21.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KND95154.1 - 0.00099 19.2 0.1 0.0012 18.9 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain Methyltransf_11 PF08241.12 KND95155.1 - 3e-12 47.0 0.0 8.9e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KND95155.1 - 5.7e-11 43.0 0.0 1.7e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KND95155.1 - 2.7e-06 27.3 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KND95155.1 - 5.5e-06 26.2 0.0 9.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KND95155.1 - 2.6e-05 23.7 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KND95155.1 - 6.5e-05 23.6 0.0 0.00021 21.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KND95155.1 - 0.00045 19.8 0.0 0.0014 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 KND95155.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.19 KND95155.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2178 PF09946.9 KND95156.1 - 0.057 13.6 0.1 0.084 13.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF1180 PF06679.12 KND95156.1 - 0.32 11.4 0.1 0.32 11.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) Cys_Met_Meta_PP PF01053.20 KND95158.1 - 2.6e-58 197.4 0.0 6.3e-58 196.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KND95158.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Polysacc_deac_1 PF01522.21 KND95159.1 - 3.5e-19 68.9 0.0 4.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KND95159.1 - 0.0045 16.2 0.0 0.011 14.9 0.0 1.6 2 0 0 2 2 2 1 Divergent polysaccharide deacetylase SIS PF01380.22 KND95159.1 - 0.031 14.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 SIS domain RP854 PF17460.2 KND95159.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 DUF1611 PF07755.11 KND95159.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Macoilin PF09726.9 KND95160.1 - 0.21 10.1 1.3 0.25 9.9 1.3 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 KND95160.1 - 0.38 9.4 13.7 0.44 9.2 13.7 1.2 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.32 KND95162.1 - 4e-15 55.9 10.9 0.008 17.0 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KND95162.1 - 7.1e-06 26.2 0.6 0.0033 17.7 0.2 4.0 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KND95162.1 - 3.6e-05 22.6 3.2 8.7e-05 21.4 1.2 2.6 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF4791 PF16039.5 KND95162.1 - 0.24 10.9 0.0 0.41 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) DUF4149 PF13664.6 KND95163.1 - 2.3e-16 60.0 0.4 9.3e-16 58.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 KND95163.1 - 0.0048 17.2 0.1 0.0058 17.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Ku_PK_bind PF08785.11 KND95164.1 - 2.1e-34 118.3 0.0 7.1e-34 116.5 0.0 1.9 2 0 0 2 2 2 1 Ku C terminal domain like Ku PF02735.16 KND95164.1 - 1.5e-26 93.4 0.0 2.7e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KND95164.1 - 1.2e-11 44.8 0.1 2.2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KND95164.1 - 0.012 15.9 0.2 0.026 14.8 0.2 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF1295 PF06966.12 KND95165.1 - 1.4e-36 126.2 6.5 1.8e-36 125.8 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KND95165.1 - 0.014 15.8 3.4 0.14 12.6 0.0 2.8 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Hydrolase_6 PF13344.6 KND95166.1 - 2.2e-26 91.9 0.0 3.4e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND95166.1 - 3e-14 52.8 0.0 7.4e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KND95166.1 - 5.2e-11 43.2 0.0 2.8e-10 40.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KND95166.1 - 0.024 14.7 0.1 0.13 12.4 0.0 2.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF3602 PF12223.8 KND95167.1 - 6.9e-08 33.0 19.7 1.4e-05 25.6 6.7 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Host_attach PF10116.9 KND95167.1 - 0.13 12.8 1.7 0.79 10.3 1.2 2.0 1 1 1 2 2 2 0 Protein required for attachment to host cells zf-C2H2 PF00096.26 KND95168.1 - 0.012 16.0 3.1 0.044 14.2 3.1 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3391 PF11871.8 KND95168.1 - 0.053 14.1 0.8 0.12 13.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) zf-BED PF02892.15 KND95168.1 - 0.12 12.4 2.2 0.27 11.3 2.2 1.6 1 0 0 1 1 1 0 BED zinc finger DnaJ PF00226.31 KND95169.1 - 0.00023 21.2 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 KND95169.1 - 0.00023 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Pam16 DUF3918 PF13056.6 KND95169.1 - 0.15 11.7 2.7 0.15 11.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Abhydrolase_1 PF00561.20 KND95170.1 - 7.7e-24 84.7 0.0 5.2e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KND95170.1 - 1.3e-18 66.9 1.1 1.7e-17 63.4 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein NUDIX PF00293.28 KND95171.1 - 0.0059 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Stb3 PF10330.9 KND95172.1 - 3.7e-37 126.2 0.0 6.4e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.20 KND95173.1 - 1.3e-101 340.6 0.0 8.8e-98 328.0 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 KND95173.1 - 1e-18 67.4 0.0 2.1e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain MMR_HSR1_Xtn PF16897.5 KND95175.1 - 4.8e-41 139.1 1.7 3.5e-40 136.3 0.4 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KND95175.1 - 2.3e-22 78.8 0.2 4.6e-22 77.8 0.2 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KND95175.1 - 9e-20 70.9 0.0 3.8e-19 68.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KND95175.1 - 4.6e-09 36.0 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KND95175.1 - 0.00034 20.2 0.1 3.5 7.1 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KND95175.1 - 0.00092 19.3 0.0 0.19 11.8 0.0 2.5 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 KND95175.1 - 0.028 13.4 0.1 0.064 12.2 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KND95175.1 - 0.05 13.5 0.3 5.8 6.8 0.1 2.8 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 KND95175.1 - 0.098 12.9 0.0 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HTH_Tnp_Tc5 PF03221.16 KND95176.1 - 1.1e-10 41.3 0.2 6e-09 35.8 0.1 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 KND95176.1 - 1.9e-08 33.8 0.1 3.3e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 KND95176.1 - 0.031 14.2 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 KND95176.1 - 0.045 13.5 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 KND95176.1 - 0.099 12.5 0.3 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain MarR_2 PF12802.7 KND95176.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.6 KND95176.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Herpes_LAMP2 PF06126.11 KND95176.1 - 0.63 8.6 3.8 0.91 8.1 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Tubulin PF00091.25 KND95177.1 - 4.2e-64 216.4 0.0 5.5e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KND95177.1 - 8.9e-43 145.5 0.0 1.4e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KND95177.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ank_2 PF12796.7 KND95179.1 - 2.1e-19 69.9 0.0 2.6e-13 50.3 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KND95179.1 - 2.7e-13 50.1 0.0 1.1e-07 32.2 0.1 4.7 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KND95179.1 - 1.2e-11 43.7 0.5 0.00062 20.0 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KND95179.1 - 4.8e-11 42.6 4.3 0.00018 21.8 0.2 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KND95179.1 - 6.9e-10 39.0 1.1 0.00043 20.5 0.5 3.5 2 1 2 4 4 4 3 Ankyrin repeats (many copies) RCR PF12273.8 KND95180.1 - 0.041 14.5 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 KND95180.1 - 0.17 12.8 0.0 0.38 11.7 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 KND95180.1 - 8.2 6.6 6.3 1.8 8.7 0.3 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) WSC PF01822.19 KND95181.1 - 8e-34 115.7 27.4 1.1e-18 67.2 9.0 5.5 5 2 0 5 5 5 2 WSC domain SOG2 PF10428.9 KND95181.1 - 3 6.9 17.7 4.7 6.3 17.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S19 PF00203.21 KND95182.1 - 7.3e-33 112.3 0.2 1.2e-32 111.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 KND95182.1 - 0.088 12.5 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor P hydroxylase Steroid_dh PF02544.16 KND95183.1 - 1e-12 48.3 2.3 1e-12 48.3 2.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KND95185.1 - 0.00092 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 KND95185.1 - 0.038 14.7 0.0 0.062 14.0 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-HC5HC2H_2 PF13832.6 KND95186.1 - 3.7e-33 114.0 8.3 3.7e-33 114.0 8.3 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KND95186.1 - 5.7e-31 108.0 0.3 2.5e-30 105.9 0.1 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KND95186.1 - 2.5e-25 88.6 8.0 2.5e-25 88.6 8.0 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 KND95186.1 - 1.1e-14 53.6 2.2 1.1e-14 53.6 2.2 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 KND95186.1 - 5.5e-08 32.6 28.6 6.9e-08 32.3 12.6 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KND95186.1 - 0.013 15.1 2.0 0.013 15.1 2.0 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain HLH PF00010.26 KND95187.1 - 4.7e-10 39.3 0.6 4.7e-10 39.3 0.6 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 KND95187.1 - 0.02 15.3 1.9 0.02 15.3 1.9 4.1 3 1 0 3 3 3 0 Cell division protein ZapB Cnn_1N PF07989.11 KND95187.1 - 0.025 14.7 1.6 0.025 14.7 1.6 3.4 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 DAO PF01266.24 KND95189.1 - 1.1e-26 94.3 0.0 1.3e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND95189.1 - 0.0033 16.7 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND95189.1 - 0.0037 17.5 0.3 0.014 15.6 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KND95189.1 - 0.025 13.7 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KND95189.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 KND95189.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family PPTA PF01239.22 KND95189.1 - 0.22 11.3 0.6 0.51 10.1 0.6 1.6 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat TMEM154 PF15102.6 KND95190.1 - 0.0033 17.3 1.3 0.0088 15.9 1.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family Kelch_3 PF13415.6 KND95190.1 - 0.014 15.7 3.7 1.7 9.0 0.2 4.8 3 1 1 4 4 4 0 Galactose oxidase, central domain Nitrate_red_gam PF02665.14 KND95190.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Rax2 PF12768.7 KND95190.1 - 0.071 12.6 1.6 0.16 11.4 0.3 2.1 2 0 0 2 2 2 0 Cortical protein marker for cell polarity CcmD PF04995.14 KND95190.1 - 0.38 10.9 2.8 0.71 10.0 2.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Mucin PF01456.17 KND95190.1 - 2.9 7.9 17.8 0.6 10.1 12.5 2.7 2 0 0 2 2 2 0 Mucin-like glycoprotein PhyH PF05721.13 KND95191.1 - 1.6e-07 31.8 0.1 8.4e-06 26.2 0.1 2.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.19 KND95191.1 - 0.059 13.3 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 AraC-like ligand binding domain DEAD PF00270.29 KND95192.1 - 2.2e-27 95.9 0.0 3.6e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND95192.1 - 9.6e-19 67.8 0.0 2.3e-17 63.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95192.1 - 2.7e-05 24.3 0.0 5.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KND95192.1 - 0.022 13.5 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain DPCD PF14913.6 KND95192.1 - 0.051 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 DPCD protein family UTP25 PF06862.12 KND95192.1 - 0.27 10.0 0.0 0.57 8.9 0.0 1.4 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AMPK1_CBM PF16561.5 KND95193.1 - 7.4e-09 35.7 0.0 1.4e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AlcCBM31 PF11606.8 KND95193.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Family 31 carbohydrate binding protein Peptidase_M76 PF09768.9 KND95195.1 - 8.6e-70 233.9 1.0 1.1e-69 233.6 1.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KND95195.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KND95195.1 - 0.033 14.5 0.1 0.049 14.0 0.1 1.2 1 0 0 1 1 1 0 Effector protein Cys_knot PF00007.22 KND95195.1 - 0.048 14.0 1.5 1 9.7 0.4 2.2 2 0 0 2 2 2 0 Cystine-knot domain UPF0113 PF03657.13 KND95196.1 - 9.9e-26 89.8 0.0 2.2e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 KND95196.1 - 1.1e-24 86.7 0.0 1.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 KND95196.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain TIP41 PF04176.13 KND95197.1 - 6.9e-68 227.5 1.4 8.5e-68 227.2 1.4 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KND95198.1 - 1.8e-70 237.4 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95198.1 - 6.9e-43 146.8 0.0 9e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND95198.1 - 7e-06 25.6 0.0 1.5e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KND95198.1 - 0.00056 19.3 0.1 0.00091 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KND95198.1 - 0.0088 15.0 3.2 0.18 10.7 3.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KND95198.1 - 0.011 15.4 0.0 0.038 13.6 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 KND95198.1 - 0.065 13.1 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KND95198.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KND95198.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Helicase_C PF00271.31 KND95200.1 - 1.3e-22 80.3 0.1 3.2e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95200.1 - 4.6e-22 78.8 0.0 9.2e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KND95200.1 - 2.2e-16 60.2 0.0 8.8e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND95200.1 - 0.0033 17.7 0.0 0.036 14.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain SWI2_SNF2 PF18766.1 KND95200.1 - 0.0035 17.1 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ArfGap PF01412.18 KND95202.1 - 1.8e-33 115.1 0.0 6.1e-33 113.4 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 KND95202.1 - 2.9e-20 73.0 16.1 4.5e-20 72.4 16.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KND95202.1 - 1.1e-11 45.2 1.5 2.4e-11 44.1 0.1 2.3 3 0 0 3 3 3 1 PH domain AAA_assoc PF14363.6 KND95202.1 - 0.066 13.5 0.8 2.6 8.4 0.9 2.6 2 0 0 2 2 2 0 Domain associated at C-terminal with AAA C2 PF00168.30 KND95203.1 - 9e-16 58.0 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 KND95203.1 - 2.8e-14 53.5 0.7 3.7e-11 43.4 0.7 2.8 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 KND95203.1 - 3.8e-11 42.3 0.1 6.8e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) K_channel_TID PF07941.11 KND95203.1 - 9.9 6.7 8.2 0.9 10.0 2.1 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-C2H2 PF00096.26 KND95204.1 - 3.1e-09 36.8 15.7 2.2e-05 24.6 4.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KND95204.1 - 6.2e-09 35.9 14.2 4.8e-05 23.6 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KND95204.1 - 2.2e-06 28.0 13.8 0.0013 19.4 3.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 KND95204.1 - 1.8e-05 24.9 1.3 1.8e-05 24.9 1.3 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KND95204.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KND95204.1 - 0.00075 19.7 1.8 0.00075 19.7 1.8 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KND95204.1 - 0.06 13.7 1.4 0.06 13.7 1.4 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KND95204.1 - 0.11 12.3 7.4 2.2 8.1 0.6 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KND95204.1 - 0.61 10.1 4.8 12 5.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SF3b1 PF08920.10 KND95205.1 - 1.1e-17 64.6 4.6 1.1e-17 64.6 4.6 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KND95205.1 - 2.3e-11 43.9 0.7 0.099 13.2 0.0 7.4 7 1 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 KND95205.1 - 1.4e-09 37.3 8.7 0.054 13.8 0.1 8.9 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 KND95205.1 - 2.6e-09 37.3 9.4 0.5 10.8 0.0 8.1 6 2 5 11 11 10 1 HEAT repeats Cnd1 PF12717.7 KND95205.1 - 2.8e-07 30.7 2.2 0.025 14.6 0.0 5.7 5 1 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KND95205.1 - 0.00036 21.1 0.0 1.5 9.5 0.0 5.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KND95205.1 - 0.0004 19.1 1.3 0.73 8.3 0.1 3.6 3 1 0 3 3 3 2 Adaptin N terminal region UNC45-central PF11701.8 KND95205.1 - 0.0008 19.4 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central NUC173 PF08161.12 KND95205.1 - 0.0012 18.6 0.3 0.8 9.3 0.0 4.7 4 2 0 5 5 5 1 NUC173 domain CLASP_N PF12348.8 KND95205.1 - 0.014 14.9 0.1 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 CLASP N terminal Dmrt1 PF12374.8 KND95205.1 - 0.38 11.2 3.1 1.2 9.7 3.1 1.9 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Opi1 PF08618.10 KND95205.1 - 0.41 9.8 6.8 0.93 8.7 6.8 1.6 1 0 0 1 1 1 0 Transcription factor Opi1 Na_Ca_ex PF01699.24 KND95206.1 - 6.1e-53 178.8 35.6 8.7e-30 103.7 14.9 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PMM PF03332.13 KND95207.1 - 3.5e-102 340.8 0.0 4.2e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KND95207.1 - 0.0029 17.4 0.0 0.078 12.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 KND95207.1 - 0.045 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Trehalose-phosphatase LGFP PF08310.11 KND95207.1 - 0.16 12.6 0.0 32 5.2 0.0 2.3 2 0 0 2 2 2 0 LGFP repeat NeA_P2 PF12312.8 KND95207.1 - 6.3 6.2 6.7 13 5.2 5.7 1.8 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein NDUFA12 PF05071.16 KND95208.1 - 9.7e-09 36.0 4.0 3.5e-08 34.2 4.0 2.1 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 KND95209.1 - 1.6e-12 47.6 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KND95209.1 - 0.23 11.3 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Siva PF05458.12 KND95211.1 - 0.3 10.8 3.2 0.63 9.7 3.2 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-B_box PF00643.24 KND95211.1 - 3.4 7.9 7.6 8.1 6.7 7.6 1.6 1 1 0 1 1 1 0 B-box zinc finger MFS_1 PF07690.16 KND95212.1 - 4.5e-36 124.5 42.2 4.5e-36 124.5 42.2 2.8 2 1 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KND95212.1 - 2.2e-12 46.6 3.9 2.2e-12 46.6 3.9 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter DAD PF02109.16 KND95212.1 - 0.1 12.9 2.6 0.5 10.7 0.0 3.0 3 0 0 3 3 3 0 DAD family OATP PF03137.20 KND95212.1 - 8 4.6 12.8 1.3 7.2 3.0 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RabGAP-TBC PF00566.18 KND95213.1 - 2e-25 89.7 0.7 5.3e-25 88.3 0.7 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4055 PF13264.6 KND95213.1 - 0.65 10.1 5.2 6.2 7.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) DUF5102 PF17104.5 KND95214.1 - 0.00049 20.2 2.2 0.024 14.7 1.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) DNA_pol_phi PF04931.13 KND95216.1 - 3e-194 647.3 22.0 6.7e-194 646.2 22.0 1.5 1 1 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 KND95216.1 - 4.9e-05 22.9 21.5 8.9e-05 22.1 21.5 1.3 1 0 0 1 1 1 1 SDA1 EB1 PF03271.17 KND95216.1 - 0.037 14.3 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 EB1-like C-terminal motif RTP1_C1 PF10363.9 KND95216.1 - 0.099 12.8 0.1 0.49 10.6 0.1 2.2 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Secretin_N PF03958.17 KND95216.1 - 0.21 12.0 1.1 16 6.0 0.0 4.0 3 1 0 3 3 3 0 Bacterial type II/III secretion system short domain GET2 PF08690.10 KND95216.1 - 0.27 10.8 7.9 0.28 10.8 4.7 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 CDC45 PF02724.14 KND95216.1 - 2.7 6.2 13.6 4.6 5.4 13.6 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KND95216.1 - 5.4 6.2 24.8 0.35 10.1 18.9 2.0 2 0 0 2 2 2 0 BUD22 Proteasome PF00227.26 KND95217.1 - 3.2e-45 153.9 0.0 8.7e-31 106.9 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KND95217.1 - 6.6e-11 41.7 0.7 9.7e-11 41.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DNA_pol_phi PF04931.13 KND95217.1 - 7.3 4.6 9.0 8.9 4.3 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CAP PF00188.26 KND95218.1 - 6.3e-21 75.5 3.2 7.8e-21 75.2 3.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-DNL PF05180.12 KND95219.1 - 2.3e-26 91.5 0.5 2.9e-26 91.2 0.5 1.1 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 KND95219.1 - 0.048 13.4 0.3 0.086 12.6 0.3 1.3 1 0 0 1 1 1 0 CSL zinc finger zf-RING_2 PF13639.6 KND95219.1 - 0.11 12.9 2.1 0.17 12.3 2.1 1.3 1 0 0 1 1 1 0 Ring finger domain zinc_ribbon_4 PF13717.6 KND95219.1 - 0.24 11.4 1.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 KND95219.1 - 0.35 10.7 1.2 24 4.9 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 KND95219.1 - 8.5 6.4 6.4 11 6.1 0.6 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Fungal_trans PF04082.18 KND95220.1 - 3.7e-16 59.0 0.5 5.6e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND95220.1 - 3.1e-07 30.4 9.1 4.9e-07 29.8 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 KND95220.1 - 0.33 11.2 1.3 0.42 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Sugarporin_N PF11471.8 KND95220.1 - 0.72 9.9 2.6 0.73 9.8 0.6 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension SNF5 PF04855.12 KND95221.1 - 4e-92 308.3 0.0 5.1e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 KND95221.1 - 0.00045 19.8 0.9 0.001 18.6 0.9 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KND95221.1 - 0.15 11.8 4.0 0.92 9.3 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Rhodanese PF00581.20 KND95222.1 - 2.2e-12 47.4 0.0 6.4e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain SOG2 PF10428.9 KND95223.1 - 1.8e-11 44.0 0.1 2.3e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein DEC-1_N PF04625.13 KND95223.1 - 0.1 11.6 0.7 0.13 11.2 0.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Arfaptin PF06456.13 KND95223.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain DRIM PF07539.12 KND95224.1 - 1.9e-198 660.7 0.0 9.8e-198 658.4 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 KND95224.1 - 5.7e-07 29.3 2.9 3.5 8.2 0.0 7.9 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 KND95224.1 - 2e-05 24.9 3.6 6.7 7.2 0.0 6.5 7 0 0 7 7 7 3 HEAT repeats Sec7_N PF12783.7 KND95224.1 - 0.12 12.3 1.6 7.9 6.4 0.2 4.5 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CwfJ_C_1 PF04677.15 KND95225.1 - 2.8e-24 85.3 0.0 1.4e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KND95225.1 - 1e-15 58.4 0.8 1.9e-15 57.5 0.8 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 GRASP55_65 PF04495.14 KND95226.1 - 2.3e-46 157.6 0.0 6.4e-45 152.9 0.0 2.0 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KND95226.1 - 0.0016 18.3 0.0 0.074 12.9 0.0 2.3 2 0 0 2 2 2 1 PDZ domain DAD PF02109.16 KND95227.1 - 2.2e-50 169.5 3.8 2.6e-50 169.3 3.8 1.1 1 0 0 1 1 1 1 DAD family HAD_2 PF13419.6 KND95228.1 - 7.4e-22 78.3 0.0 9.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KND95228.1 - 1.5e-08 35.2 0.0 0.00045 20.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KND95228.1 - 0.00061 19.8 0.1 0.00095 19.2 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KND95228.1 - 0.0029 18.0 0.0 0.0045 17.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_C15 PF01470.17 KND95229.1 - 3.3e-13 50.3 0.0 2e-06 28.1 0.0 2.8 3 1 0 3 3 3 2 Pyroglutamyl peptidase DUF5562 PF17717.1 KND95229.1 - 0.02 14.9 0.9 0.031 14.2 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5562) DUF4110 PF13422.6 KND95230.1 - 4.5e-30 103.6 1.1 4.5e-30 103.6 1.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 KND95230.1 - 5.6e-28 96.7 17.7 5e-08 32.8 0.0 7.3 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KND95230.1 - 3.7e-25 87.6 6.2 3e-08 33.8 0.3 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KND95230.1 - 9.7e-19 66.9 3.1 3.4e-06 26.9 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 KND95230.1 - 7.7e-15 54.6 4.4 0.0018 18.5 0.3 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 KND95230.1 - 1.2e-12 47.3 3.6 0.00013 21.8 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KND95230.1 - 3e-10 39.5 4.0 0.002 17.6 0.1 5.0 5 0 0 5 5 5 3 Kelch motif PI3K_1B_p101 PF10486.9 KND95230.1 - 3.4 5.3 7.9 7.2 4.3 7.9 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Methyltransf_15 PF09445.10 KND95231.1 - 2.3e-44 150.9 0.0 3.1e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 KND95231.1 - 0.0035 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_5 PF01795.19 KND95231.1 - 0.013 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family tRNA_U5-meth_tr PF05958.11 KND95231.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 KND95231.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.6 KND95231.1 - 0.19 12.5 0.0 0.64 10.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain FF PF01846.19 KND95232.1 - 2.2e-38 130.2 3.4 2e-11 43.9 1.0 6.4 6 0 0 6 6 6 4 FF domain WW PF00397.26 KND95232.1 - 2.1e-16 59.7 17.5 8.2e-10 38.6 4.9 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 KND95232.1 - 0.00058 20.5 6.9 0.3 11.8 0.0 4.7 3 1 1 4 4 4 1 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 KND95232.1 - 0.87 9.9 7.5 4.2 7.7 1.6 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 KND95233.1 - 3.4e-123 411.1 0.0 5.2e-123 410.5 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 KduI PF04962.12 KND95233.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family SLD3 PF08639.10 KND95234.1 - 5.7e-168 560.0 6.6 5.7e-168 560.0 6.6 2.4 2 1 0 2 2 2 2 DNA replication regulator SLD3 Homeodomain PF00046.29 KND95235.1 - 1.1e-15 57.1 2.4 2.8e-15 55.9 2.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KND95235.1 - 0.0012 18.8 0.6 0.0028 17.5 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF5593 PF18007.1 KND95235.1 - 0.18 12.5 0.1 1.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5593) DUF3584 PF12128.8 KND95235.1 - 0.54 7.7 8.3 0.77 7.2 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rdx PF10262.9 KND95236.1 - 1e-33 115.4 0.0 1.4e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KND95237.1 - 3.2e-24 84.7 0.0 4e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain Cupin_8 PF13621.6 KND95238.1 - 3.4e-19 69.6 0.1 5.1e-17 62.4 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 KND95238.1 - 5.3e-10 39.7 0.1 1.3e-09 38.4 0.1 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 KND95238.1 - 8.1e-07 28.8 0.7 1.9e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND95238.1 - 2e-05 24.3 0.0 4.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.12 KND95238.1 - 0.056 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 KND95238.1 - 0.082 12.6 0.1 0.74 9.6 0.0 2.4 3 0 0 3 3 3 0 Cupin domain DEAD PF00270.29 KND95239.1 - 1e-45 155.7 0.8 1.6e-45 155.0 0.8 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND95239.1 - 7.7e-32 109.9 0.1 1.4e-30 105.9 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95239.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KND95239.1 - 0.00039 20.2 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KND95239.1 - 0.00062 20.1 0.7 0.009 16.3 0.4 2.3 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KND95239.1 - 0.015 15.4 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 KND95239.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KND95239.1 - 0.091 12.7 0.1 0.35 10.8 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain fragilysinNterm PF16376.5 KND95239.1 - 0.1 12.3 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of fragilysin AAA_22 PF13401.6 KND95239.1 - 0.11 12.8 0.4 0.58 10.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain IATP PF04568.12 KND95240.1 - 1.7e-34 118.1 1.8 2e-34 117.9 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.12 KND95240.1 - 0.049 13.6 0.2 0.062 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF2205 PF10224.9 KND95240.1 - 0.15 12.1 5.1 0.2 11.7 5.1 1.2 1 0 0 1 1 1 0 Short coiled-coil protein DUF1003 PF06210.11 KND95240.1 - 1.4 9.1 3.6 2.2 8.4 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) 14-3-3 PF00244.20 KND95242.1 - 6.8e-101 336.4 7.4 1.7e-89 299.1 1.3 2.0 2 0 0 2 2 2 2 14-3-3 protein Mitoc_mL59 PF18126.1 KND95243.1 - 3.1e-41 140.7 6.0 3.1e-41 140.7 6.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KND95243.1 - 7.8e-16 57.6 0.1 1.1e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KND95243.1 - 2.3e-11 43.6 0.0 6.2e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 DnaJ domain MARVEL PF01284.23 KND95244.1 - 0.00066 19.7 8.9 0.00067 19.7 7.8 1.6 1 1 0 1 1 1 1 Membrane-associating domain Vut_1 PF02592.15 KND95244.1 - 0.019 15.3 4.2 0.035 14.4 4.2 1.3 1 0 0 1 1 1 0 Putative vitamin uptake transporter Vma12 PF11712.8 KND95244.1 - 0.11 12.6 0.9 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ninjurin PF04923.12 KND95244.1 - 0.2 11.6 3.0 0.17 11.8 0.3 2.1 1 1 1 2 2 2 0 Ninjurin DUF2721 PF11026.8 KND95244.1 - 1.1 9.2 6.5 6.9 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) eIF2_C PF09173.11 KND95245.1 - 2.6e-34 117.3 0.5 6.1e-34 116.1 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KND95245.1 - 1.7e-22 79.9 1.5 1.1e-21 77.3 1.5 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KND95245.1 - 1e-09 38.6 0.2 2.2e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 KND95245.1 - 0.0048 16.9 0.9 0.017 15.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KND95245.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KND95245.1 - 0.025 14.5 0.2 0.23 11.4 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF5102 PF17104.5 KND95246.1 - 1.2e-112 376.7 0.9 1.2e-112 376.7 0.9 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5102) Papilin_u7 PF16626.5 KND95246.1 - 0.041 14.5 0.6 0.041 14.5 0.6 2.8 3 0 0 3 3 3 0 Linking region between Kunitz_BPTI and I-set on papilin Nsp1_C PF05064.13 KND95247.1 - 2.5e-37 127.2 2.5 2.5e-37 127.2 2.5 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KND95247.1 - 6.3e-07 30.1 111.0 2.7e-06 28.1 32.8 7.8 2 1 7 9 9 9 5 Nucleoporin FG repeat region MAS20 PF02064.15 KND95247.1 - 0.22 11.6 1.5 0.48 10.5 1.5 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor ERM PF00769.19 KND95247.1 - 0.93 9.3 7.3 1.5 8.6 7.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family V-SNARE PF05008.15 KND95247.1 - 3.2 8.2 9.5 1.8 9.0 0.6 3.0 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Laminin_II PF06009.12 KND95247.1 - 7.2 6.6 6.1 76 3.3 0.4 2.6 1 1 1 2 2 2 0 Laminin Domain II Complex1_49kDa PF00346.19 KND95249.1 - 6.5e-124 412.4 0.0 8.8e-124 412.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KND95249.1 - 0.0037 16.2 0.0 0.0068 15.4 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase FAD_binding_3 PF01494.19 KND95250.1 - 1.2e-23 84.0 0.0 3.3e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KND95250.1 - 6.5e-05 22.1 1.0 0.002 17.2 0.1 3.1 4 0 0 4 4 4 1 Lycopene cyclase protein DAO PF01266.24 KND95250.1 - 0.00042 20.0 0.2 0.087 12.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KND95250.1 - 0.0049 16.1 0.0 0.0095 15.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KND95250.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 KND95250.1 - 0.018 15.0 0.0 0.041 13.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 KND95250.1 - 0.022 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KND95250.1 - 0.029 13.3 0.0 0.6 8.9 0.0 2.4 2 1 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KND95250.1 - 0.044 14.0 0.2 0.11 12.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KND95250.1 - 0.15 11.3 0.0 0.51 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family ELMO_CED12 PF04727.13 KND95251.1 - 1e-48 165.8 0.0 2.7e-48 164.4 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KND95251.1 - 1.4e-38 132.4 0.0 2.7e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KND95251.1 - 1.5e-14 54.2 0.0 3.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) VIT1 PF01988.19 KND95252.1 - 1e-60 205.3 4.0 7e-60 202.6 4.0 1.9 1 1 0 1 1 1 1 VIT family DUF4813 PF16072.5 KND95252.1 - 0.18 11.4 3.7 0.3 10.7 3.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4813) DUF1768 PF08719.11 KND95253.1 - 2.9e-15 56.9 0.0 3.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ketoacyl-synt PF00109.26 KND95254.1 - 2.5e-80 269.7 0.0 5.2e-80 268.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KND95254.1 - 5.4e-52 176.9 2.3 5.2e-51 173.7 0.1 2.9 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KND95254.1 - 2.3e-37 129.2 1.7 2.4e-37 129.1 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KND95254.1 - 5.9e-31 106.9 0.5 1.8e-30 105.4 0.5 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KND95254.1 - 2.5e-23 82.5 0.0 4.1e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KND95254.1 - 8e-21 74.2 11.3 2e-10 40.9 1.3 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KND95254.1 - 2.2e-08 33.7 0.1 5.6e-08 32.4 0.1 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.21 KND95254.1 - 1.1e-06 28.3 0.0 2.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 KND95254.1 - 2.4e-05 24.7 0.0 9.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KND95254.1 - 8.4e-05 22.1 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.10 KND95254.1 - 0.0092 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KND95254.1 - 0.012 14.8 0.0 0.078 12.1 0.0 2.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KND95254.1 - 0.032 13.3 0.0 7.6 5.5 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Methyltransf_2 PF00891.18 KND95255.1 - 8.2e-28 97.1 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KND95255.1 - 0.025 15.3 0.0 0.1 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain ATP-grasp_2 PF08442.10 KND95256.1 - 3e-46 157.5 0.0 5.9e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ribul_P_3_epim PF00834.19 KND95256.1 - 1.3e-43 148.7 0.0 5.6e-42 143.4 0.0 2.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Ligase_CoA PF00549.19 KND95256.1 - 4.8e-15 55.7 0.7 1.1e-14 54.5 0.7 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KND95256.1 - 5e-08 32.7 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain OMPdecase PF00215.24 KND95256.1 - 0.12 11.9 0.1 0.36 10.4 0.1 1.8 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family CFEM PF05730.11 KND95257.1 - 3.9e-14 52.5 12.9 6.9e-14 51.7 12.9 1.4 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 KND95257.1 - 1.3 7.1 11.0 1.4 6.9 11.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.11 KND95257.1 - 5.8 5.1 12.1 7 4.8 12.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_6 PF12697.7 KND95258.1 - 1.6e-20 74.7 0.3 3e-20 73.8 0.2 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KND95258.1 - 1.2e-10 41.5 0.0 2.5e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KND95258.1 - 3.5e-07 29.7 0.1 5.3e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KND95258.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KND95258.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 KND95258.1 - 0.097 11.2 0.1 4 5.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 KND95258.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 KND95258.1 - 0.16 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Zn_clus PF00172.18 KND95259.1 - 3.8e-08 33.3 8.3 6.8e-08 32.5 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.15 KND95260.1 - 1.1e-40 138.3 1.9 2.7e-40 137.1 0.2 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KND95260.1 - 1.2e-32 112.5 20.0 3.1e-32 111.2 0.3 4.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 KND95260.1 - 2.7e-30 105.6 0.0 2.1e-29 102.7 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase DUF3324 PF11797.8 KND95260.1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) CW_binding_1 PF01473.20 KND95261.1 - 0.029 14.7 0.4 0.051 13.9 0.4 1.4 1 0 0 1 1 1 0 Putative cell wall binding repeat Fungal_trans PF04082.18 KND95262.1 - 1.1e-19 70.6 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mannosidase_ig PF17786.1 KND95262.1 - 1.6e-14 54.3 0.2 4e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Zn_clus PF00172.18 KND95262.1 - 1.4e-07 31.5 14.2 3.5e-07 30.2 14.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ig_mannosidase PF17753.1 KND95262.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Dus PF01207.17 KND95263.1 - 3.8e-58 197.0 0.0 5.4e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) adh_short PF00106.25 KND95264.1 - 1.2e-08 34.6 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KND95264.1 - 1.3e-06 28.2 0.1 1.5e-06 28.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DHFR_1 PF00186.19 KND95266.1 - 2e-21 76.4 0.0 3.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrofolate reductase DSBA PF01323.20 KND95266.1 - 0.033 14.0 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Ubiq_cyt_C_chap PF03981.12 KND95267.1 - 8.2e-33 113.5 0.0 1.2e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Sugar_tr PF00083.24 KND95268.1 - 1.7e-66 224.9 25.4 2e-66 224.7 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KND95268.1 - 4.9e-20 71.8 49.4 2.1e-15 56.5 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KND95271.1 - 7.2e-10 38.2 0.4 1.1e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND95271.1 - 4.4e-08 33.1 9.1 8.5e-08 32.2 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LYRIC PF15686.5 KND95271.1 - 0.071 12.7 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family AAA PF00004.29 KND95273.1 - 5e-51 172.6 0.0 2.1e-42 144.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KND95273.1 - 2.4e-09 36.8 0.4 8.8e-09 35.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KND95273.1 - 2.9e-08 34.3 0.1 0.00079 19.8 0.3 3.4 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 KND95273.1 - 1.9e-06 27.7 0.0 1.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 KND95273.1 - 2.6e-05 24.4 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KND95273.1 - 0.0009 19.4 0.2 0.027 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KND95273.1 - 0.0016 18.5 0.0 0.008 16.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KND95273.1 - 0.0019 18.5 0.1 0.054 13.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND95273.1 - 0.0084 16.5 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KND95273.1 - 0.0092 16.5 0.4 0.037 14.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KND95273.1 - 0.0096 15.2 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KND95273.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KND95273.1 - 0.03 14.4 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KND95273.1 - 0.062 12.7 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KND95273.1 - 0.077 12.5 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KND95273.1 - 0.088 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KND95273.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 KND95273.1 - 0.11 12.2 0.0 3.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KND95273.1 - 0.15 12.2 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1945 PF09178.10 KND95275.1 - 0.085 13.1 0.4 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) RNase_T PF00929.24 KND95276.1 - 1.9e-24 87.1 0.0 5.5e-24 85.6 0.0 1.7 2 0 0 2 2 2 1 Exonuclease PGM_PMM_III PF02880.16 KND95276.1 - 5.8e-24 84.5 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 KND95276.1 - 5.3e-19 68.3 0.0 3.7e-15 55.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KND95276.1 - 1e-15 58.2 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KND95276.1 - 7.1e-06 26.1 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 KND95277.1 - 7.7e-10 39.6 0.0 2.2e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KND95277.1 - 0.00024 21.1 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Cleaved_Adhesin PF07675.11 KND95277.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Cleaved Adhesin Domain ImpA_N PF06812.12 KND95277.1 - 0.078 13.1 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system F-box-like PF12937.7 KND95278.1 - 0.002 18.0 1.0 0.002 18.0 1.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KND95278.1 - 0.36 10.8 5.6 11 6.1 0.2 3.2 3 0 0 3 3 3 0 F-box domain ATG11 PF10377.9 KND95279.1 - 1.4e-39 135.1 0.2 1.4e-39 135.1 0.2 3.6 4 1 0 4 4 4 1 Autophagy-related protein 11 HOOK PF05622.12 KND95279.1 - 1.6e-05 23.3 57.5 1.6e-05 23.3 57.5 2.9 3 0 0 3 3 3 1 HOOK protein APG17 PF04108.12 KND95279.1 - 6.1e-05 22.3 8.0 6.1e-05 22.3 8.0 4.2 2 2 1 3 3 3 1 Autophagy protein Apg17 DUF4407 PF14362.6 KND95279.1 - 0.0028 17.0 17.2 0.0028 17.0 17.2 5.3 4 2 1 5 5 5 3 Domain of unknown function (DUF4407) Spc7 PF08317.11 KND95279.1 - 0.0043 16.0 13.3 0.0043 16.0 13.3 6.0 4 3 2 7 7 7 3 Spc7 kinetochore protein FERM_f0 PF16511.5 KND95279.1 - 0.0059 16.9 0.2 0.72 10.2 0.0 2.7 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM LOH1CR12 PF10158.9 KND95279.1 - 8.3 6.4 12.5 1.8 8.6 0.3 4.0 3 1 0 3 3 3 0 Tumour suppressor protein CENP-H PF05837.12 KND95281.1 - 1e-30 106.4 3.2 1.9e-29 102.4 0.3 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DivIC PF04977.15 KND95281.1 - 0.056 13.2 6.5 1.3 8.9 1.5 3.0 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.11 KND95281.1 - 0.058 13.6 9.9 0.19 11.9 2.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 KND95281.1 - 0.13 12.7 6.9 5.5 7.4 7.0 2.2 1 1 0 1 1 1 0 Fez1 Biotin_lipoyl PF00364.22 KND95282.1 - 4.1e-21 74.6 1.1 7.6e-21 73.7 1.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KND95282.1 - 3.6e-11 43.2 0.1 1.5e-10 41.2 0.1 2.1 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KND95282.1 - 0.00036 20.3 0.1 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KND95282.1 - 0.00085 20.0 1.6 0.18 12.5 0.0 2.7 1 1 1 2 2 2 2 HlyD family secretion protein YqfD PF06898.11 KND95282.1 - 0.033 13.0 0.9 0.096 11.5 0.7 1.7 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD HMG_box PF00505.19 KND95283.1 - 8.3e-25 87.0 1.0 1.3e-24 86.4 1.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KND95283.1 - 8.7e-18 64.7 2.1 1.7e-17 63.8 2.1 1.5 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 KND95283.1 - 0.0023 18.5 1.4 0.0061 17.1 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 KND95283.1 - 0.016 15.2 0.5 0.033 14.1 0.5 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 SVIP PF15811.5 KND95283.1 - 3.5 8.2 7.0 0.38 11.2 0.7 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein EF-hand_4 PF12763.7 KND95284.1 - 1.3e-25 89.3 0.0 2.6e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KND95284.1 - 9.6e-05 22.1 2.2 0.0028 17.4 0.3 2.7 2 0 0 2 2 2 1 WH2 motif DUF1720 PF08226.11 KND95284.1 - 0.00013 22.3 107.2 0.00057 20.2 19.4 7.8 6 2 2 8 8 8 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 KND95284.1 - 0.0031 17.9 0.0 0.29 11.6 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 KND95284.1 - 0.058 13.3 0.1 6.6 6.9 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain tRNA-synt_1d PF00750.19 KND95285.1 - 8e-60 202.6 3.4 9.2e-43 146.5 1.9 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 KND95285.1 - 2.8e-24 85.5 0.3 1.2e-23 83.5 0.1 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain LRR_4 PF12799.7 KND95286.1 - 7.9e-13 48.4 4.9 0.0005 20.4 0.3 4.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KND95286.1 - 3.2e-11 42.8 5.3 5.3e-07 29.3 1.1 3.6 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 KND95286.1 - 0.008 15.7 0.2 0.017 14.6 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 KND95286.1 - 0.036 14.6 10.1 1e+02 4.1 0.4 6.1 5 2 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 KND95286.1 - 0.082 13.0 6.6 41 4.6 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat DUF2497 PF10691.9 KND95287.1 - 0.072 13.5 0.2 0.4 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) HupH_C PF04809.13 KND95287.1 - 0.19 11.4 0.0 0.7 9.6 0.0 1.8 2 0 0 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region Peroxin-3 PF04882.12 KND95289.1 - 2.7e-171 570.7 0.0 3.2e-171 570.5 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 RPE65 PF03055.15 KND95291.1 - 7.5e-119 397.9 0.0 8.5e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Forkhead PF00250.18 KND95292.1 - 1.2e-33 115.2 0.0 2.1e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Fungal_trans PF04082.18 KND95293.1 - 4.5e-25 88.2 0.5 7.1e-25 87.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UCH PF00443.29 KND95294.1 - 3.4e-36 125.1 0.0 5.3e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 KND95294.1 - 7.7e-23 80.0 0.1 1.9e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 KND95294.1 - 3.7e-22 78.4 3.4 5.3e-20 71.5 1.3 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KND95294.1 - 4.8e-16 58.3 2.0 1.9e-09 37.1 0.0 3.5 3 0 0 3 3 3 2 Variant UBP zinc finger UCH_1 PF13423.6 KND95294.1 - 1.2e-15 58.0 0.0 2e-14 53.9 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ABC_tran PF00005.27 KND95295.1 - 3.6e-32 111.7 0.0 5.1e-15 56.2 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KND95295.1 - 3.9e-12 45.8 4.4 3.9e-12 45.8 4.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KND95295.1 - 6e-11 42.7 6.1 0.19 11.5 1.5 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KND95295.1 - 1.7e-10 40.7 0.4 0.0018 17.8 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KND95295.1 - 2.8e-06 27.7 0.0 0.00059 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KND95295.1 - 3.7e-06 26.9 0.0 0.19 11.4 0.0 3.1 3 1 0 4 4 4 2 AAA ATPase domain Fer4 PF00037.27 KND95295.1 - 9.9e-06 25.2 2.7 9.9e-06 25.2 2.7 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.29 KND95295.1 - 1.4e-05 25.5 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KND95295.1 - 2.3e-05 24.8 0.0 0.029 14.8 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Fer4_10 PF13237.6 KND95295.1 - 8e-05 22.7 8.4 0.0046 17.0 0.1 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Rad17 PF03215.15 KND95295.1 - 9e-05 22.5 0.1 0.036 14.0 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_23 PF13476.6 KND95295.1 - 0.00026 21.6 0.2 0.034 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KND95295.1 - 0.00037 20.8 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 KND95295.1 - 0.00039 20.1 0.1 0.62 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_21 PF14697.6 KND95295.1 - 0.00044 20.3 10.0 0.00086 19.4 10.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 KND95295.1 - 0.00044 20.2 0.0 0.93 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 KND95295.1 - 0.00053 20.5 0.0 1.3 9.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KND95295.1 - 0.0013 18.7 0.4 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KND95295.1 - 0.0013 18.5 0.5 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 KND95295.1 - 0.0019 17.9 1.8 0.099 12.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KND95295.1 - 0.0019 18.4 0.0 0.42 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 KND95295.1 - 0.0024 17.9 11.5 0.0032 17.5 1.7 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 KND95295.1 - 0.0041 17.1 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KND95295.1 - 0.0046 15.7 0.2 0.016 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KND95295.1 - 0.0052 17.3 6.8 0.012 16.2 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_7 PF12775.7 KND95295.1 - 0.0058 16.2 0.6 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Thymidylate_kin PF02223.17 KND95295.1 - 0.0074 16.0 0.5 3.1 7.4 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase AAA_5 PF07728.14 KND95295.1 - 0.011 15.7 0.5 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 KND95295.1 - 0.023 14.9 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KND95295.1 - 0.038 13.7 0.2 3.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KND95295.1 - 0.039 14.1 10.4 0.085 13.0 10.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain NB-ARC PF00931.22 KND95295.1 - 0.053 12.7 0.0 4.1 6.5 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KND95295.1 - 0.094 12.8 0.6 14 5.8 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 KND95295.1 - 0.098 12.4 0.0 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_16 PF13484.6 KND95295.1 - 0.1 13.6 0.3 0.1 13.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain PduV-EutP PF10662.9 KND95295.1 - 0.15 11.8 3.7 0.63 9.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KND95295.1 - 0.22 11.4 1.5 6.1 6.7 0.0 2.6 2 0 0 2 2 2 0 NTPase CLP1_P PF16575.5 KND95295.1 - 0.53 10.0 1.4 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_2 PF12797.7 KND95295.1 - 0.99 9.6 10.2 0.3 11.3 1.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain FTA4 PF13093.6 KND95296.1 - 4.1e-62 209.7 0.0 5.1e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Seryl_tRNA_N PF02403.22 KND95296.1 - 0.016 15.4 1.0 0.65 10.3 0.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HORMA PF02301.18 KND95297.1 - 1.9e-22 79.9 0.0 3.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 HORMA domain DUF3530 PF12048.8 KND95297.1 - 2.6 7.4 8.8 0.051 13.0 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) MA3 PF02847.17 KND95299.1 - 1.8e-24 85.9 0.0 7.7e-24 83.9 0.0 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KND95299.1 - 2.4e-11 43.7 0.3 2.4e-11 43.7 0.3 2.2 2 1 0 2 2 2 1 MIF4G domain FAM176 PF14851.6 KND95299.1 - 0.28 10.9 4.1 0.77 9.4 4.1 1.8 1 0 0 1 1 1 0 FAM176 family Chitin_bind_1 PF00187.19 KND95300.1 - 0.0041 17.6 39.1 0.012 16.1 18.0 4.5 4 0 0 4 4 4 2 Chitin recognition protein FAD_binding_3 PF01494.19 KND95301.1 - 2.8e-15 56.4 0.0 5.3e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KND95301.1 - 4.9e-05 23.1 3.5 0.14 11.7 0.0 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KND95301.1 - 9.9e-05 21.6 0.2 0.00025 20.2 0.0 1.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 KND95301.1 - 0.00011 21.6 0.3 0.0014 17.9 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KND95301.1 - 0.00042 20.5 0.0 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KND95301.1 - 0.045 13.1 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KND95301.1 - 0.048 12.7 2.1 0.14 11.2 0.5 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 KND95301.1 - 0.048 12.3 0.1 0.3 9.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ADH_zinc_N PF00107.26 KND95302.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KND95302.1 - 0.0033 17.3 0.4 0.0065 16.3 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3453 PF11935.8 KND95303.1 - 6.1e-68 228.8 0.1 2.6e-67 226.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.9 KND95304.1 - 2.4e-05 24.3 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 RRM_1 PF00076.22 KND95305.1 - 3.2e-13 49.3 0.5 1.3e-09 37.7 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 KND95305.1 - 0.72 8.1 13.5 1.1 7.4 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.12 KND95305.1 - 1.6 6.7 5.6 2.2 6.1 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein adh_short_C2 PF13561.6 KND95306.1 - 2e-28 99.6 0.5 2.6e-28 99.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KND95306.1 - 8.7e-19 67.7 0.2 1.5e-18 67.0 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KND95306.1 - 0.00011 22.2 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 KND95306.1 - 0.051 14.0 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KND95306.1 - 0.12 11.7 0.1 0.32 10.3 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFMR PF07777.11 KND95306.1 - 0.22 12.0 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Eno-Rase_NADH_b PF12242.8 KND95306.1 - 0.29 10.9 2.0 0.78 9.6 2.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DEAD PF00270.29 KND95308.1 - 1.5e-41 142.1 0.0 5.6e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KND95308.1 - 4.9e-31 107.4 0.1 1.2e-30 106.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KND95308.1 - 4.1e-06 26.9 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KND95308.1 - 0.0059 15.4 0.0 0.0088 14.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 KND95308.1 - 0.012 15.3 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Cwf_Cwc_15 PF04889.12 KND95308.1 - 0.094 12.4 8.6 0.16 11.7 8.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 KND95308.1 - 0.3 11.5 7.6 0.92 9.9 7.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 KND95308.1 - 0.76 10.2 9.3 2.3 8.6 9.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF413 PF04219.12 KND95309.1 - 0.052 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF SAD_SRA PF02182.17 KND95310.1 - 9.5e-07 28.6 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Pkinase PF00069.25 KND95311.1 - 1.6e-63 214.5 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KND95311.1 - 9.9e-35 120.1 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KND95311.1 - 5.7e-06 25.9 0.0 9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KND95311.1 - 0.00024 20.0 0.0 0.00034 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KND95311.1 - 0.11 12.1 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TruD PF01142.18 KND95312.1 - 1.5e-59 201.9 0.2 7.5e-57 193.0 0.0 2.6 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Ribosomal_S8 PF00410.19 KND95313.1 - 4.5e-22 78.4 0.0 6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.12 KND95314.1 - 1.5e-18 66.9 8.1 1.3e-15 57.3 6.3 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 Rotamase_3 PF13616.6 KND95315.1 - 7.3e-17 62.0 0.1 1.4e-16 61.0 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KND95315.1 - 6.9e-14 52.6 0.1 9.6e-14 52.1 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KND95315.1 - 9.3e-05 23.3 1.6 0.00022 22.1 1.6 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.26 KND95316.1 - 1.2e-27 95.5 1.5 1.5e-27 95.1 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KND95316.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RalF_SCD PF18248.1 KND95316.1 - 0.19 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain Mon1 PF03164.14 KND95317.1 - 4.6e-152 506.8 0.0 5.3e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 CblD PF07434.11 KND95317.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator DUF3432 PF11914.8 KND95317.1 - 0.14 12.4 4.7 0.29 11.4 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Dopey_N PF04118.14 KND95318.1 - 5.4e-116 387.0 0.0 1.7e-115 385.4 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal HEAT_EZ PF13513.6 KND95318.1 - 0.004 17.6 4.9 8.4 7.0 0.1 4.8 4 0 0 4 4 4 2 HEAT-like repeat Fungal_trans PF04082.18 KND95319.1 - 8.4e-15 54.5 0.4 1.2e-14 54.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND95319.1 - 1.4e-08 34.7 11.0 3.8e-08 33.3 11.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.14 KND95320.1 - 7.8e-124 413.3 2.9 9.1e-124 413.1 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_1 PF00561.20 KND95323.1 - 5.8e-13 49.1 0.0 1.5e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KND95323.1 - 2.7e-08 34.7 0.2 3.7e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KND95323.1 - 1.6e-07 30.9 0.0 5.8e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KND95323.1 - 8.6e-05 21.4 0.0 0.00036 19.3 0.0 1.9 1 1 0 1 1 1 1 Ndr family Glyco_hydro_18 PF00704.28 KND95324.1 - 8.2e-12 45.5 0.0 4.2e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 AtuA PF07287.11 KND95325.1 - 4.9e-29 101.1 0.1 3.4e-18 65.5 0.0 3.0 2 1 1 3 3 3 3 Acyclic terpene utilisation family protein AtuA ECH_1 PF00378.20 KND95326.1 - 4.2e-44 150.7 0.0 6.4e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KND95326.1 - 2.7e-18 66.6 0.0 4.2e-18 65.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KND95326.1 - 0.0014 18.6 0.1 0.0078 16.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 DUF3005 PF11448.8 KND95326.1 - 0.075 13.1 0.0 11 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) TLP1_add_C PF18313.1 KND95327.1 - 1.9e-21 75.8 0.0 4.3e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Prefoldin_2 PF01920.20 KND95328.1 - 5.2e-19 68.2 10.6 3e-16 59.3 1.4 2.0 2 0 0 2 2 2 2 Prefoldin subunit DUF4757 PF15949.5 KND95328.1 - 0.0086 16.6 1.5 0.021 15.3 1.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4757) FadA PF09403.10 KND95328.1 - 0.19 12.2 7.3 1.5 9.3 1.0 2.2 2 0 0 2 2 2 0 Adhesion protein FadA Tho2 PF11262.8 KND95328.1 - 0.33 10.1 3.2 2.9 7.0 2.9 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Prefoldin PF02996.17 KND95328.1 - 0.7 9.8 6.1 1.8 8.5 0.2 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF148 PF02520.17 KND95328.1 - 1.6 8.8 8.8 1.4 9.0 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 PH PF00169.29 KND95329.1 - 1.1e-05 25.9 0.5 7.8e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 PH domain SAM_2 PF07647.17 KND95329.1 - 2.7e-05 24.2 0.0 5.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sod_Fe_C PF02777.18 KND95330.1 - 1.5e-13 50.8 0.0 9.1e-12 45.1 0.0 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KND95330.1 - 0.0043 17.5 0.0 0.007 16.8 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain STIMATE PF12400.8 KND95331.1 - 3.9e-40 137.3 2.6 6.8e-40 136.5 2.6 1.4 1 0 0 1 1 1 1 STIMATE family IBR PF01485.21 KND95331.1 - 4.4e-10 39.6 50.1 1.2e-06 28.6 7.8 4.0 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain FAD_binding_6 PF00970.24 KND95332.1 - 4.5e-29 100.7 0.0 7.3e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KND95332.1 - 2.9e-27 95.5 0.0 4.2e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KND95332.1 - 0.00068 19.8 0.0 0.047 13.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Fungal_trans PF04082.18 KND95334.1 - 1.6e-30 106.0 0.2 3e-30 105.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND95334.1 - 2.6e-05 24.2 15.5 9.2e-05 22.5 15.5 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.14 KND95334.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Mid2 PF04478.12 KND95335.1 - 0.0003 20.7 0.1 0.00065 19.6 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 KND95335.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 KND95335.1 - 0.00064 20.6 0.0 0.0054 17.6 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.16 KND95335.1 - 0.00077 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 KND95335.1 - 0.009 16.5 5.0 0.009 16.5 5.0 2.5 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM51 PF15345.6 KND95335.1 - 0.041 13.7 1.1 0.069 13.0 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 51 DAP10 PF07213.11 KND95335.1 - 0.048 13.6 0.7 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 DAP10 membrane protein PTP_tm PF18861.1 KND95335.1 - 0.052 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Syndecan PF01034.20 KND95335.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Granulin PF00396.18 KND95335.1 - 1.4 9.3 28.1 0.4 11.0 5.4 3.6 2 1 1 3 3 3 0 Granulin Lustrin_cystein PF14625.6 KND95335.1 - 3.9 7.9 21.9 6.3 7.3 8.5 2.9 2 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain PI-PLC-X PF00388.19 KND95336.1 - 6.8e-09 35.5 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain F-box-like PF12937.7 KND95337.1 - 2.2e-06 27.5 0.1 5.6e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KND95337.1 - 0.029 14.3 0.3 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 F-box domain Fungal_trans_2 PF11951.8 KND95338.1 - 1.4e-84 284.2 0.3 1.7e-84 283.9 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KND95338.1 - 2.5e-08 33.9 6.3 5.2e-08 32.9 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 KND95339.1 - 5e-23 79.9 30.2 0.00011 21.9 0.1 12.5 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 KND95339.1 - 8.9e-23 78.5 33.4 0.00039 20.3 0.2 13.0 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_8 PF13181.6 KND95339.1 - 1.7e-18 65.2 20.6 0.0012 18.9 0.1 11.5 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 KND95339.1 - 6.3e-16 57.2 8.8 0.00097 19.0 0.0 9.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 KND95339.1 - 2.9e-14 53.1 23.1 0.00027 21.1 1.3 9.8 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KND95339.1 - 7.2e-13 48.2 24.3 0.0057 17.4 0.1 12.3 12 2 2 14 14 11 2 Tetratricopeptide repeat TPR_10 PF13374.6 KND95339.1 - 2.7e-11 43.0 9.2 0.032 14.1 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KND95339.1 - 6.7e-10 39.0 23.8 0.029 15.0 0.0 10.5 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 KND95339.1 - 1.1e-09 38.6 31.8 0.019 15.5 0.1 10.1 9 3 4 13 13 12 5 Tetratricopeptide repeat TPR_17 PF13431.6 KND95339.1 - 2.7e-09 36.8 10.1 0.14 12.6 0.1 10.2 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 KND95339.1 - 4.4e-09 36.8 24.0 0.016 15.8 0.1 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 KND95339.1 - 2e-05 24.2 20.8 0.053 13.2 0.2 8.2 8 1 1 9 9 9 2 TPR repeat Cohesin_load PF10345.9 KND95339.1 - 0.0055 15.2 1.2 2.2 6.6 0.1 2.8 2 1 1 3 3 3 2 Cohesin loading factor ANAPC3 PF12895.7 KND95339.1 - 0.012 15.9 18.5 1.8 8.9 0.5 6.9 8 0 0 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 ChpA-C PF03777.13 KND95339.1 - 0.57 10.1 2.2 1.3 8.9 2.2 1.5 1 0 0 1 1 1 0 ChpA-C SNF2_N PF00176.23 KND95340.1 - 1.9e-54 184.7 0.0 3e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KND95340.1 - 3e-26 91.1 8.4 2.1e-16 59.6 1.4 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KND95340.1 - 4.5e-20 71.9 0.0 2.1e-19 69.8 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KND95340.1 - 6.9e-19 68.2 0.0 1.9e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KND95340.1 - 1.6e-07 30.8 0.0 5.4e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KND95340.1 - 2.4e-06 27.9 0.4 2.4e-06 27.9 0.4 4.5 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KND95340.1 - 0.00024 21.2 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KND95340.1 - 0.0037 17.3 4.5 0.0054 16.7 0.0 3.3 3 0 0 3 3 3 1 SLIDE CDH1_2_SANT_HL1 PF18375.1 KND95340.1 - 0.013 16.1 1.2 0.013 16.1 1.2 2.7 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 MaoC_dehydratas PF01575.19 KND95341.1 - 9.1e-21 73.7 0.0 1.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain CAP_GLY PF01302.25 KND95341.1 - 2.2e-19 69.2 0.1 4.5e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 KND95341.1 - 5.3e-11 42.1 3.5 0.0036 17.0 2.7 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KND95341.1 - 9.1e-10 38.6 3.0 0.32 11.5 0.1 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KND95341.1 - 2.9e-07 30.2 0.0 0.00025 20.6 0.0 2.8 2 1 1 3 3 3 3 Leucine-rich repeat MaoC_dehydrat_N PF13452.6 KND95341.1 - 0.00043 20.4 0.0 0.0021 18.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase LRR_6 PF13516.6 KND95341.1 - 0.00043 20.1 7.8 1.2 9.4 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 KND95341.1 - 0.0068 16.8 0.1 73 4.5 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat ATG101 PF07855.12 KND95343.1 - 2.9e-36 124.8 0.0 3.4e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 KND95343.1 - 0.045 13.8 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Spherulin4 PF12138.8 KND95344.1 - 1.8e-44 152.2 0.1 2.2e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 ATP_bind_1 PF03029.17 KND95345.1 - 5.1e-72 242.5 0.0 1.3e-71 241.2 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KND95345.1 - 0.0003 20.7 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KND95345.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KND95345.1 - 0.0041 16.9 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KND95345.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 KND95345.1 - 0.011 15.3 0.0 5.8 6.4 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 KND95345.1 - 0.011 16.3 0.1 0.038 14.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KND95345.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 KND95345.1 - 0.019 14.7 0.1 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase CbiA PF01656.23 KND95345.1 - 0.019 15.0 0.0 0.02 15.0 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 KND95345.1 - 0.023 14.6 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 KND95345.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KND95345.1 - 0.037 14.5 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KND95345.1 - 0.042 14.0 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KND95345.1 - 0.048 13.4 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase MMR_HSR1 PF01926.23 KND95345.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.7 KND95345.1 - 0.068 12.1 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.22 KND95345.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain S-AdoMet_synt_C PF02773.16 KND95346.1 - 1.4e-66 222.7 0.4 3.6e-66 221.4 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KND95346.1 - 7.9e-46 155.2 0.0 1.4e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KND95346.1 - 5.5e-44 148.9 0.5 1.1e-43 147.9 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain MSP1b PF03429.13 KND95346.1 - 0.16 10.0 0.0 0.3 9.1 0.0 1.3 1 0 0 1 1 1 0 Major surface protein 1B PX PF00787.24 KND95347.1 - 8.9e-21 74.0 0.0 5.3e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KND95347.1 - 9.1e-12 45.0 4.8 1.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KND95347.1 - 0.045 13.2 0.3 0.078 12.4 0.3 1.4 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein MSC PF09402.10 KND95349.1 - 1.2e-116 389.9 0.0 1.8e-116 389.3 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 KND95349.1 - 1.5e-15 56.6 0.1 2.7e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 KND95349.1 - 0.0022 17.6 0.1 0.0057 16.2 0.1 1.6 1 0 0 1 1 1 1 Thymopoietin protein EGF_MSP1_1 PF12946.7 KND95349.1 - 0.76 9.9 2.2 1.4 9.0 2.2 1.4 1 0 0 1 1 1 0 MSP1 EGF domain 1 Mt_ATP-synt_B PF05405.14 KND95350.1 - 3.7e-55 186.0 6.7 3.7e-55 186.0 6.7 1.3 2 0 0 2 2 2 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Virul_Fac PF10139.9 KND95350.1 - 0.01 14.1 3.4 0.012 13.9 3.4 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor VPS9 PF02204.18 KND95351.1 - 4.1e-27 94.4 0.0 6.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KND95351.1 - 1e-15 57.8 0.1 2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KND95351.1 - 3.1e-08 33.1 0.1 2.7e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 CUE domain adh_short_C2 PF13561.6 KND95351.1 - 3.6e-05 23.4 0.0 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TRP PF06011.12 KND95352.1 - 8.3e-149 495.9 14.8 1.1e-148 495.6 14.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KND95352.1 - 6e-40 136.8 1.7 1.2e-39 135.9 1.7 1.5 1 0 0 1 1 1 1 ML-like domain TMEM154 PF15102.6 KND95352.1 - 0.12 12.3 4.0 2.3 8.1 0.9 2.7 2 1 0 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 KND95352.1 - 0.95 9.9 3.6 0.95 9.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sod_Cu PF00080.20 KND95353.1 - 1.8e-12 47.6 0.0 2.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) FAM165 PF14981.6 KND95355.1 - 0.25 11.2 0.6 0.67 9.8 0.6 1.7 1 0 0 1 1 1 0 FAM165 family COX14 PF14880.6 KND95355.1 - 0.61 10.0 6.5 0.84 9.5 1.2 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Glucosamine_iso PF01182.20 KND95357.1 - 2.7e-69 233.5 0.0 3.1e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF846 PF05832.12 KND95358.1 - 2.5e-50 170.1 12.7 3.1e-50 169.8 12.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 KND95358.1 - 0.22 10.9 11.4 0.23 10.8 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4870 PF09685.10 KND95358.1 - 3.8 7.7 13.9 1 9.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) HpcH_HpaI PF03328.14 KND95361.1 - 1.2e-46 158.7 0.3 3.2e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KND95361.1 - 9.5e-13 48.0 0.1 1.2e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Malate_synthase PF01274.22 KND95361.1 - 0.16 10.2 0.0 2.1 6.5 0.0 2.3 3 0 0 3 3 3 0 Malate synthase Acylphosphatase PF00708.18 KND95362.1 - 3.7e-22 78.5 0.2 4e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase HA2 PF04408.23 KND95363.1 - 3.7e-22 78.6 0.0 3.7e-22 78.6 0.0 3.7 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KND95363.1 - 1e-19 70.6 0.0 3.4e-19 69.0 0.0 1.9 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KND95363.1 - 3.5e-13 49.9 0.0 8.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KND95363.1 - 7.4e-07 29.1 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KND95363.1 - 2.1e-05 24.8 0.1 5.7e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KND95363.1 - 8.1e-05 22.4 0.1 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KND95363.1 - 0.0013 19.1 0.1 0.0031 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KND95363.1 - 0.0019 17.5 0.0 0.0046 16.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KND95363.1 - 0.0026 17.8 0.0 0.59 10.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KND95363.1 - 0.0031 16.6 0.0 0.0069 15.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 KND95363.1 - 0.0087 15.7 0.3 0.02 14.5 0.3 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KND95363.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain GAD PF02938.14 KND95363.1 - 0.048 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 GAD domain ABC_tran PF00005.27 KND95363.1 - 0.058 13.9 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.6 KND95363.1 - 0.087 12.9 0.1 0.55 10.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF1363 PF07101.11 KND95363.1 - 0.093 13.0 0.2 0.3 11.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1363) AAA_33 PF13671.6 KND95363.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.4 3 1 0 3 3 1 0 AAA domain zf-UDP PF14569.6 KND95364.1 - 0.59 10.3 4.0 1.3 9.2 4.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger C1_2 PF03107.16 KND95364.1 - 4.1 7.8 7.1 1.1 9.6 3.7 1.8 2 0 0 2 2 2 0 C1 domain Hep_59 PF07052.11 KND95365.1 - 2.8e-07 31.3 0.4 1.2e-06 29.2 0.0 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 zf-HYPF PF07503.12 KND95366.1 - 0.029 14.1 0.4 0.068 13.0 0.4 1.6 1 0 0 1 1 1 0 HypF finger EF-hand_1 PF00036.32 KND95367.1 - 1.2e-23 80.8 9.9 1.7e-07 30.2 0.2 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 KND95367.1 - 3.3e-19 69.1 7.8 3e-08 34.0 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KND95367.1 - 1.6e-18 65.0 9.3 0.00019 21.1 0.1 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 KND95367.1 - 2.6e-14 52.8 12.1 5.2e-08 32.6 0.2 4.9 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 KND95367.1 - 4.7e-14 51.1 7.2 0.00071 19.0 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KND95367.1 - 0.0044 17.3 0.5 2.1 8.7 0.0 3.1 3 1 0 3 3 3 2 EF-hand domain GUN4 PF05419.12 KND95367.1 - 0.12 12.5 0.0 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.7 KND95367.1 - 2.4 8.1 4.0 5.6 7.0 0.2 2.7 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Lactamase_B_3 PF13483.6 KND95368.1 - 7.8e-07 29.1 0.0 9.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KND95368.1 - 8.8e-07 28.6 0.1 1.1e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RRM_1 PF00076.22 KND95369.1 - 5.8e-19 67.7 0.0 8.4e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.12 KND95370.1 - 1.5e-38 132.6 0.0 2.4e-38 132.0 0.0 1.4 1 1 0 1 1 1 1 ChaC-like protein SBDS_C PF09377.10 KND95371.1 - 1.4e-45 154.0 0.0 2.7e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KND95371.1 - 1.5e-34 117.9 0.2 2.6e-34 117.1 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.22 KND95372.1 - 5.4e-56 188.5 3.2 6.4e-56 188.2 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KND95372.1 - 0.019 13.8 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin-6_N PF09177.11 KND95372.1 - 0.11 13.1 0.0 0.41 11.2 0.0 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PP28 PF10252.9 KND95372.1 - 0.22 12.0 1.0 0.35 11.3 0.4 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Peptidase_M22 PF00814.25 KND95373.1 - 2.5e-43 148.7 7.5 5.2e-29 101.8 6.2 3.0 2 1 0 2 2 2 2 Glycoprotease family Proteasome PF00227.26 KND95374.1 - 5.1e-47 159.8 0.3 6.1e-47 159.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_129 PF11308.8 KND95374.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 Glyco_hydro_16 PF00722.21 KND95375.1 - 1.4e-08 34.4 0.0 7.6e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.12 KND95376.1 - 1.9e-13 50.7 0.1 2.3e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MFS_2 PF13347.6 KND95377.1 - 1.1e-07 30.7 5.7 1.1e-07 30.7 5.7 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein UPF0154 PF03672.13 KND95377.1 - 0.5 10.4 0.0 0.5 10.4 0.0 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0154) DUF4134 PF13572.6 KND95378.1 - 0.14 12.5 0.5 0.19 12.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Sec62 PF03839.16 KND95380.1 - 0.38 10.2 1.8 0.45 10.0 1.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1932 PF09130.11 KND95381.1 - 4.2e-23 81.1 0.1 1.1e-22 79.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KND95381.1 - 8.3e-08 32.7 0.0 1.7e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KND95381.1 - 3.2e-06 27.4 0.0 5.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KND95381.1 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KND95381.1 - 0.0046 16.8 0.7 0.0087 15.9 0.7 1.4 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 KND95381.1 - 0.0051 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 KND95381.1 - 0.011 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Shikimate_DH PF01488.20 KND95381.1 - 0.052 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.22 KND95384.1 - 5.4e-18 64.6 0.0 9e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KND95384.1 - 0.00023 21.7 19.6 0.00023 21.7 19.6 4.5 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KND95385.1 - 6.1e-18 64.4 0.0 1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KND95385.1 - 3.1e-05 24.4 16.5 3.1e-05 24.4 16.5 4.7 3 2 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 UQ_con PF00179.26 KND95386.1 - 5.8e-31 107.0 0.0 7.1e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KND95386.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B BphX PF06139.12 KND95386.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 BphX-like Anp1 PF03452.14 KND95387.1 - 6.5e-109 363.4 0.0 7.6e-109 363.2 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KND95387.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PRA1 PF03208.19 KND95388.1 - 8.1e-36 122.8 1.0 1.2e-35 122.3 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein tRNA-synt_1 PF00133.22 KND95390.1 - 1.2e-222 740.5 0.1 2.4e-221 736.2 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KND95390.1 - 8.6e-33 113.5 0.7 2.7e-32 111.8 0.7 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 KND95390.1 - 1.9e-13 50.3 0.0 5.8e-10 39.0 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KND95390.1 - 4.3e-13 48.8 0.0 1e-05 24.5 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 KND95390.1 - 2.4e-05 24.5 4.9 2.4e-05 24.5 4.9 2.9 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KND95390.1 - 0.044 13.1 0.6 0.78 9.0 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tolypocladium_ophioglossoides_CBS_100239-Tophv1.0/GCA_001189435.1_Tophv1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tolypocladium_ophioglossoides_CBS_100239-Tophv1.0/GCA_001189435.1_Tophv1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tolypocladium_ophioglossoides_CBS_100239-Tophv1.0/GCA_001189435.1_Tophv1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tolypocladium_ophioglossoides_CBS_100239-Tophv1.0/GCA_001189435.1_Tophv1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:29:50 2019 # [ok]